Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 50
• Symbol: ACO2
• Description: aconitase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ACO2

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41523826	41523849	22	+	26472758	Jiyoye	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.1086627585604625	[162]	[56]	-6	hSpCas9	negative selection	1583
41522965	41522988	22	-	26472758	Jiyoye	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-2.578885427536253	[308]	[38]	-9	hSpCas9	negative selection	1584
41508021	41508044	22	+	26472758	Jiyoye	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	1585
41511912	41511935	22	+	26472758	Jiyoye	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-1.662533590305531	[423]	[100]	-8	hSpCas9	negative selection	1586
41524914	41524937	22	+	26472758	Jiyoye	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-2.442929188011068	[273]	[37]	-8	hSpCas9	negative selection	1587
41507950	41507973	22	+	26472758	Jiyoye	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.2284131922852507	[86]	[55]	-2	hSpCas9	negative selection	1590
41515839	41515862	22	+	26472758	Jiyoye	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.114361739073649	[177]	[61]	-6	hSpCas9	negative selection	1591
41520254	41520277	22	+	26472758	Jiyoye	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-0.6302993239127896	[38]	[18]	-4	hSpCas9	negative selection	1592
41523826	41523849	22	+	26472758	KBM7	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.0627332425438551	[1047,853]	[271,159]	-7	hSpCas9	negative selection	192701
41522965	41522988	22	-	26472758	KBM7	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.305514551863941	[1446,1354]	[52,78]	-9	hSpCas9	negative selection	192702
41508021	41508044	22	+	26472758	KBM7	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.361218707376923	[65,45]	[3,5]	-9	hSpCas9	negative selection	192703
41511912	41511935	22	+	26472758	KBM7	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-2.863955672676492	[1195,817]	[80,48]	-9	hSpCas9	negative selection	192704
41524914	41524937	22	+	26472758	KBM7	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-4.792219845199253	[752,488]	[12,7]	-9	hSpCas9	negative selection	192705
41507950	41507973	22	+	26472758	KBM7	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-1.8897954824567518	[294,309]	[44,32]	-8	hSpCas9	negative selection	192708
41515839	41515862	22	+	26472758	KBM7	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.9611008323191907	[765,750]	[158,31]	-8	hSpCas9	negative selection	192709
41520254	41520277	22	+	26472758	KBM7	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.0530752807668116	[305,253]	[97,31]	-7	hSpCas9	negative selection	192710
41523826	41523849	22	+	26472758	Raji	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-2.5303853245222103	[472]	[18]	-9	hSpCas9	negative selection	383819
41522965	41522988	22	-	26472758	Raji	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-0.885311664003167	[787]	[98]	-6	hSpCas9	negative selection	383820
41508021	41508044	22	+	26472758	Raji	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-1.565041806597896	[50]	[3]	-8	hSpCas9	negative selection	383821
41511912	41511935	22	+	26472758	Raji	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.9841148191118966	[536]	[62]	-6	hSpCas9	negative selection	383822
41524914	41524937	22	+	26472758	Raji	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-2.0478946901043114	[391]	[21]	-8	hSpCas9	negative selection	383823
41507950	41507973	22	+	26472758	Raji	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.8835713250233936	[158]	[19]	-6	hSpCas9	negative selection	383826
41515839	41515862	22	+	26472758	Raji	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.813862353211989	[302]	[19]	-8	hSpCas9	negative selection	383827
41520254	41520277	22	+	26472758	Raji	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.507326308741609	[195]	[15]	-8	hSpCas9	negative selection	383828
41523826	41523849	22	+	26472758	K562	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.4358057655650798	[938]	[292]	-6	hSpCas9	negative selection	574937
41522965	41522988	22	-	26472758	K562	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.2396148642039284	[1241]	[110]	-8	hSpCas9	negative selection	574938
41508021	41508044	22	+	26472758	K562	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-5.66247186794207	[59]	[0]	-9	hSpCas9	negative selection	574939
41511912	41511935	22	+	26472758	K562	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-1.338934520193052	[895]	[298]	-6	hSpCas9	negative selection	574940
41524914	41524937	22	+	26472758	K562	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-2.047251546128235	[518]	[105]	-7	hSpCas9	negative selection	574941
41507950	41507973	22	+	26472758	K562	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.7832123913107436	[368]	[180]	-4	hSpCas9	negative selection	574944
41515839	41515862	22	+	26472758	K562	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.8351016119770795	[633]	[149]	-7	hSpCas9	negative selection	574945
41520254	41520277	22	+	26472758	K562	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-3.0775093672209155	[269]	[26]	-8	hSpCas9	negative selection	574946
41507902	41507925	22	+	26627737	DLD1	viability	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-4.6472349090354985	[659]	[1,8,12]	-9	hSpCas9	negative selection	818020
41515951	41515974	22	-	26627737	DLD1	viability	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.7656666933967102	[1589]	[371,183,312]	-6	hSpCas9	negative selection	818021
41517610	41517633	22	+	26627737	DLD1	viability	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-2.8654946355310837	[688]	[84,5,0]	-9	hSpCas9	negative selection	818022
41520258	41520281	22	-	26627737	DLD1	viability	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.7816837890374284	[778]	[4,45,52]	-9	hSpCas9	negative selection	818023
41523267	41523290	22	-	26627737	DLD1	viability	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.7150096174032803	[93]	[0,55,0]	-6	hSpCas9	negative selection	818024
41524897	41524920	22	+	26627737	DLD1	viability	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-1.5950849473320559	[277]	[1,41,40]	-8	hSpCas9	negative selection	818025
41507902	41507925	22	+	26627737	GBM cells	viability after 5 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.023083613113041287	[233]	[103,142]	0	hSpCas9	negative selection	900335
41515951	41515974	22	-	26627737	GBM cells	viability after 5 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.8196731899656661	[779]	[212,260]	-8	hSpCas9	negative selection	900336
41517610	41517633	22	+	26627737	GBM cells	viability after 5 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.009697580650174786	[366]	[226,163]	0	hSpCas9	negative selection	900337
41520258	41520281	22	-	26627737	GBM cells	viability after 5 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-1.0293503715154	[254]	[104,28]	-9	hSpCas9	negative selection	900338
41523267	41523290	22	-	26627737	GBM cells	viability after 5 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	0.4197460381871261	[68]	[52,45]	6	hSpCas9	negative selection	900339
41524897	41524920	22	+	26627737	GBM cells	viability after 5 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	0.17392092238555557	[99]	[66,53]	2	hSpCas9	negative selection	900340
41507902	41507925	22	+	26627737	GBM cells	viability after 13 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.8889911481264302	[233]	[83,55]	-8	hSpCas9	negative selection	982650
41515951	41515974	22	-	26627737	GBM cells	viability after 13 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.2734706245161256	[779]	[412,298]	-3	hSpCas9	negative selection	982651
41517610	41517633	22	+	26627737	GBM cells	viability after 13 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.5758045734157655	[366]	[153,116]	-6	hSpCas9	negative selection	982652
41520258	41520281	22	-	26627737	GBM cells	viability after 13 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-1.2638114722631628	[254]	[50,62]	-8	hSpCas9	negative selection	982653
41523267	41523290	22	-	26627737	GBM cells	viability after 13 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.28666928929022584	[68]	[33,27]	-3	hSpCas9	negative selection	982654
41524897	41524920	22	+	26627737	GBM cells	viability after 13 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-0.7495393525869734	[99]	[23,38]	-7	hSpCas9	negative selection	982655
41507902	41507925	22	+	26627737	GBM cells	viability after 21 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.5792325714472604	[233]	[82,86]	-5	hSpCas9	negative selection	1064965
41515951	41515974	22	-	26627737	GBM cells	viability after 21 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.11210094939665871	[779]	[401,382]	-1	hSpCas9	negative selection	1064966
41517610	41517633	22	+	26627737	GBM cells	viability after 21 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.38107248061512883	[366]	[138,165]	-3	hSpCas9	negative selection	1064967
41520258	41520281	22	-	26627737	GBM cells	viability after 21 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-4.0004937155112055	[254]	[4,11]	-9	hSpCas9	negative selection	1064968
41523267	41523290	22	-	26627737	GBM cells	viability after 21 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.8872542393274436	[68]	[13,25]	-6	hSpCas9	negative selection	1064969
41524897	41524920	22	+	26627737	GBM cells	viability after 21 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	0.24112816808686177	[99]	[70,57]	2	hSpCas9	negative selection	1064970
41507902	41507925	22	+	26627737	RPE1	viability after 9 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.6147969606324163	[946]	[152,245]	-4	hSpCas9	negative selection	1147280
41515951	41515974	22	-	26627737	RPE1	viability after 9 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.24067605630177757	[1973]	[543,495]	-2	hSpCas9	negative selection	1147281
41517610	41517633	22	+	26627737	RPE1	viability after 9 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.2407462031654995	[959]	[324,393]	1	hSpCas9	negative selection	1147282
41520258	41520281	22	-	26627737	RPE1	viability after 9 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	0.2947050301073626	[289]	[106,116]	2	hSpCas9	negative selection	1147283
41523267	41523290	22	-	26627737	RPE1	viability after 9 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-1.30208741115228	[69]	[14,0]	-7	hSpCas9	negative selection	1147284
41524897	41524920	22	+	26627737	RPE1	viability after 9 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-1.6968657573433628	[347]	[23,45]	-8	hSpCas9	negative selection	1147285
41507902	41507925	22	+	26627737	RPE1	viability after 12 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.40872524717586733	[946]	[213,167]	-3	hSpCas9	negative selection	1229595
41515951	41515974	22	-	26627737	RPE1	viability after 12 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.25740057074277933	[1973]	[466,418]	-2	hSpCas9	negative selection	1229596
41517610	41517633	22	+	26627737	RPE1	viability after 12 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.1845402892093682	[959]	[228,360]	1	hSpCas9	negative selection	1229597
41520258	41520281	22	-	26627737	RPE1	viability after 12 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	0.47108982382167175	[289]	[141,71]	3	hSpCas9	negative selection	1229598
41523267	41523290	22	-	26627737	RPE1	viability after 12 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	1.0585582335624308	[69]	[10,68]	6	hSpCas9	negative selection	1229599
41524897	41524920	22	+	26627737	RPE1	viability after 12 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-0.769976104925177	[347]	[82,24]	-5	hSpCas9	negative selection	1229600
41507902	41507925	22	+	26627737	RPE1	viability after 15 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.7155826256326752	[946]	[211,115]	-4	hSpCas9	negative selection	1311910
41515951	41515974	22	-	26627737	RPE1	viability after 15 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.37321959284643	[1973]	[536,328]	-2	hSpCas9	negative selection	1311911
41517610	41517633	22	+	26627737	RPE1	viability after 15 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.1983002920529019	[959]	[197,273]	-1	hSpCas9	negative selection	1311912
41520258	41520281	22	-	26627737	RPE1	viability after 15 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-0.0892557399538636	[289]	[126,28]	0	hSpCas9	negative selection	1311913
41523267	41523290	22	-	26627737	RPE1	viability after 15 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-1.3781886966368577	[69]	[0,13]	-7	hSpCas9	negative selection	1311914
41524897	41524920	22	+	26627737	RPE1	viability after 15 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-1.6924920400329004	[347]	[60,0]	-8	hSpCas9	negative selection	1311915
41507902	41507925	22	+	26627737	RPE1	viability after 18 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-1.252128931042132	[946]	[42,175]	-6	hSpCas9	negative selection	1394225
41515951	41515974	22	-	26627737	RPE1	viability after 18 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.26225247572138954	[1973]	[390,500]	-2	hSpCas9	negative selection	1394226
41517610	41517633	22	+	26627737	RPE1	viability after 18 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.6931434336056312	[959]	[385,453]	4	hSpCas9	negative selection	1394227
41520258	41520281	22	-	26627737	RPE1	viability after 18 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-0.8533615686759453	[289]	[37,48]	-5	hSpCas9	negative selection	1394228
41523267	41523290	22	-	26627737	RPE1	viability after 18 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.5673234881074225	[69]	[19,4]	-4	hSpCas9	negative selection	1394229
41524897	41524920	22	+	26627737	RPE1	viability after 18 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-2.754738171611958	[347]	[25,0]	-9	hSpCas9	negative selection	1394230
41507902	41507925	22	+	26627737	HeLa	viability after 8 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	0.37769948578211593	[357]	[102,378,109]	3	hSpCas9	negative selection	1476540
41515951	41515974	22	-	26627737	HeLa	viability after 8 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.13354314902606834	[924]	[502,294,334]	-1	hSpCas9	negative selection	1476541
41517610	41517633	22	+	26627737	HeLa	viability after 8 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.014666420585978224	[689]	[557,178,233]	0	hSpCas9	negative selection	1476542
41520258	41520281	22	-	26627737	HeLa	viability after 8 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-1.2429494883614627	[414]	[142,0,97]	-8	hSpCas9	negative selection	1476543
41523267	41523290	22	-	26627737	HeLa	viability after 8 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.3370458531175018	[15]	[0,0,12]	-3	hSpCas9	negative selection	1476544
41524897	41524920	22	+	26627737	HeLa	viability after 8 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-0.6249116929493919	[130]	[31,28,47]	-6	hSpCas9	negative selection	1476545
41507902	41507925	22	+	26627737	HeLa	viability after 12 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.09635655309207197	[357]	[159,211,35]	-1	hSpCas9	negative selection	1558855
41515951	41515974	22	-	26627737	HeLa	viability after 12 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.08800512050288978	[924]	[472,276,340]	0	hSpCas9	negative selection	1558856
41517610	41517633	22	+	26627737	HeLa	viability after 12 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.1752473229670235	[689]	[341,175,463]	1	hSpCas9	negative selection	1558857
41520258	41520281	22	-	26627737	HeLa	viability after 12 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-1.7077230723348709	[414]	[21,48,85]	-9	hSpCas9	negative selection	1558858
41523267	41523290	22	-	26627737	HeLa	viability after 12 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-2.3191457662120367	[15]	[0,0,1]	-9	hSpCas9	negative selection	1558859
41524897	41524920	22	+	26627737	HeLa	viability after 12 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-0.5211565201780897	[130]	[12,41,56]	-5	hSpCas9	negative selection	1558860
41507902	41507925	22	+	26627737	HeLa	viability after 15 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.19026465353897593	[357]	[179,44,159]	-2	hSpCas9	negative selection	1641170
41515951	41515974	22	-	26627737	HeLa	viability after 15 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.5329786559436791	[924]	[335,168,275]	-5	hSpCas9	negative selection	1641171
41517610	41517633	22	+	26627737	HeLa	viability after 15 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.21400450199756782	[689]	[319,60,352]	-2	hSpCas9	negative selection	1641172
41520258	41520281	22	-	26627737	HeLa	viability after 15 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.5858955859670787	[414]	[0,76,4]	-9	hSpCas9	negative selection	1641173
41523267	41523290	22	-	26627737	HeLa	viability after 15 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	0.2726094556436971	[15]	[19,0,1]	2	hSpCas9	negative selection	1641174
41524897	41524920	22	+	26627737	HeLa	viability after 15 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	0.7283050083836935	[130]	[19,180,62]	6	hSpCas9	negative selection	1641175
41507902	41507925	22	+	26627737	HeLa	viability after 18 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.19132826355628535	[357]	[115,42,159]	-2	hSpCas9	negative selection	1723485
41515951	41515974	22	-	26627737	HeLa	viability after 18 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.5542061965613936	[924]	[221,134,275]	-5	hSpCas9	negative selection	1723486
41517610	41517633	22	+	26627737	HeLa	viability after 18 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.20398586882182634	[689]	[215,52,352]	-2	hSpCas9	negative selection	1723487
41520258	41520281	22	-	26627737	HeLa	viability after 18 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.572184983520073	[414]	[0,63,4]	-9	hSpCas9	negative selection	1723488
41523267	41523290	22	-	26627737	HeLa	viability after 18 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.07556185460595266	[15]	[9,0,1]	0	hSpCas9	negative selection	1723489
41524897	41524920	22	+	26627737	HeLa	viability after 18 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	0.8294611520123895	[130]	[16,160,62]	6	hSpCas9	negative selection	1723490
41507902	41507925	22	+	26627737	HCT116	viability after 6 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	0.07482110216569188	[754]	[66,156]	0	hSpCas9	negative selection	1805800
41515951	41515974	22	-	26627737	HCT116	viability after 6 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	1.2767678702975225	[1020]	[696,218]	6	hSpCas9	negative selection	1805801
41517610	41517633	22	+	26627737	HCT116	viability after 6 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.15878089507415727	[1295]	[70,243]	-1	hSpCas9	negative selection	1805802
41520258	41520281	22	-	26627737	HCT116	viability after 6 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.155610467035083	[334]	[25,3]	-8	hSpCas9	negative selection	1805803
41523267	41523290	22	-	26627737	HCT116	viability after 6 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	4.087116908436111	[115]	[6,476]	9	hSpCas9	negative selection	1805804
41524897	41524920	22	+	26627737	HCT116	viability after 6 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-0.11585542439077301	[35]	[1,6]	0	hSpCas9	negative selection	1805805
41507902	41507925	22	+	26627737	HCT116	viability after 8 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-1.2643390451508043	[289]	[41,79,76]	-9	hSpCas9	negative selection	1888115
41515951	41515974	22	-	26627737	HCT116	viability after 8 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.42229661268399266	[844]	[364,437,240]	-5	hSpCas9	negative selection	1888116
41517610	41517633	22	+	26627737	HCT116	viability after 8 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	0.28726469332868276	[261]	[201,68,256]	3	hSpCas9	negative selection	1888117
41520258	41520281	22	-	26627737	HCT116	viability after 8 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.400736426648094	[343]	[0,64,40]	-9	hSpCas9	negative selection	1888118
41523267	41523290	22	-	26627737	HCT116	viability after 8 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	0.8175534182758577	[24]	[33,13,24]	7	hSpCas9	negative selection	1888119
41524897	41524920	22	+	26627737	HCT116	viability after 8 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-1.2101503646000524	[35]	[20,0,3]	-9	hSpCas9	negative selection	1888120
41507902	41507925	22	+	26627737	HCT116	viability after 9 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-2.032170048826499	[754]	[98,9]	-8	hSpCas9	negative selection	1970430
41515951	41515974	22	-	26627737	HCT116	viability after 9 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	0.3859050168491188	[1020]	[353,357]	3	hSpCas9	negative selection	1970431
41517610	41517633	22	+	26627737	HCT116	viability after 9 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.08282671011017972	[1295]	[166,452]	0	hSpCas9	negative selection	1970432
41520258	41520281	22	-	26627737	HCT116	viability after 9 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	0.4986812152034096	[334]	[136,117]	3	hSpCas9	negative selection	1970433
41523267	41523290	22	-	26627737	HCT116	viability after 9 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-2.87089010355921	[115]	[1,5]	-9	hSpCas9	negative selection	1970434
41524897	41524920	22	+	26627737	HCT116	viability after 9 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-2.7374229615515873	[35]	[1,0]	-9	hSpCas9	negative selection	1970435
41507902	41507925	22	+	26627737	HCT116	viability after 12 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-2.150519226961189	[289]	[73,13,10]	-9	hSpCas9	negative selection	2052745
41515951	41515974	22	-	26627737	HCT116	viability after 12 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.18773094258633938	[844]	[200,461,524]	-2	hSpCas9	negative selection	2052746
41517610	41517633	22	+	26627737	HCT116	viability after 12 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.28285122756319325	[261]	[72,110,158]	-3	hSpCas9	negative selection	2052747
41520258	41520281	22	-	26627737	HCT116	viability after 12 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.7721850445129994	[343]	[5,59,15]	-9	hSpCas9	negative selection	2052748
41523267	41523290	22	-	26627737	HCT116	viability after 12 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	0.26867678348290447	[24]	[39,0,3]	2	hSpCas9	negative selection	2052749
41524897	41524920	22	+	26627737	HCT116	viability after 12 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-2.0430921226566467	[35]	[0,0,11]	-9	hSpCas9	negative selection	2052750
41507902	41507925	22	+	26627737	HCT116	viability after 15 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-4.4237227467364875	[289]	[12,9,0]	-9	hSpCas9	negative selection	2135060
41515951	41515974	22	-	26627737	HCT116	viability after 15 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.7796751126794602	[844]	[317,224,308]	-7	hSpCas9	negative selection	2135061
41517610	41517633	22	+	26627737	HCT116	viability after 15 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.031248796612476953	[261]	[201,66,178]	0	hSpCas9	negative selection	2135062
41520258	41520281	22	-	26627737	HCT116	viability after 15 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-1.8930311282265335	[343]	[12,31,108]	-9	hSpCas9	negative selection	2135063
41523267	41523290	22	-	26627737	HCT116	viability after 15 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-1.9427128240106963	[24]	[9,0,0]	-9	hSpCas9	negative selection	2135064
41524897	41524920	22	+	26627737	HCT116	viability after 15 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-1.1912116589740145	[35]	[0,0,23]	-8	hSpCas9	negative selection	2135065
41507902	41507925	22	+	26627737	HCT116	viability after 18 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-3.724978678793806	[289]	[29,0,0]	-9	hSpCas9	negative selection	2217375
41515951	41515974	22	-	26627737	HCT116	viability after 18 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-1.037304854690246	[844]	[132,252,207]	-7	hSpCas9	negative selection	2217376
41517610	41517633	22	+	26627737	HCT116	viability after 18 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.2740728408336548	[261]	[87,10,226]	-3	hSpCas9	negative selection	2217377
41520258	41520281	22	-	26627737	HCT116	viability after 18 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-2.3563522814399493	[343]	[1,22,74]	-9	hSpCas9	negative selection	2217378
41523267	41523290	22	-	26627737	HCT116	viability after 18 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.9970058092784999	[24]	[0,0,16]	-7	hSpCas9	negative selection	2217379
41524897	41524920	22	+	26627737	HCT116	viability after 18 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-4.12137262578689	[35]	[0,0,0]	-9	hSpCas9	negative selection	2217380
41469153	41469176	22	-	24336569	HL60	viability	CGAGTCACCAGTAGGCTGTAGGG	ACO2	ENSG00000100412	-0.3459205815318883	[811]	[1351]	-3	hSpCas9	negative selection	2246373
41469161	41469184	22	+	24336569	HL60	viability	CCTACTGGTGACTCGGCTGCAGG	ACO2	ENSG00000100412	0.1796607151962663	[440]	[1056]	1	hSpCas9	negative selection	2246374
41499713	41499736	22	+	24336569	HL60	viability	TTTCTTCTTGCAGAAAGCTCTGG	ACO2	ENSG00000100412	0.5514784289940816	[206]	[641]	5	hSpCas9	negative selection	2246375
41499778	41499801	22	-	24336569	HL60	viability	AAAGTGGCTCATCGCCACCTTGG	ACO2	ENSG00000100412	0.5978907703672145	[561]	[1799]	5	hSpCas9	negative selection	2246376
41499804	41499827	22	-	24336569	HL60	viability	TCATAATGGATGTACTCGTTGGG	ACO2	ENSG00000100412	-0.4794951746020504	[1517]	[2303]	-4	hSpCas9	negative selection	2246377
41499818	41499841	22	-	24336569	HL60	viability	TCTTCTCTAGCAGGTCATAATGG	ACO2	ENSG00000100412	-0.8781191340292918	[402]	[463]	-7	hSpCas9	negative selection	2246378
41499841	41499864	22	+	24336569	HL60	viability	ACATTAACATTGTTCGCAAACGG	ACO2	ENSG00000100412	0.6402771335527034	[180]	[596]	5	hSpCas9	negative selection	2246379
41507794	41507817	22	+	24336569	HL60	viability	GAACCGGCCGCTGACACTCTCGG	ACO2	ENSG00000100412	-0.451241663984521	[386]	[598]	-4	hSpCas9	negative selection	2246380
41507801	41507824	22	-	24336569	HL60	viability	ATCTTCTCCGAGAGTGTCAGCGG	ACO2	ENSG00000100412	1.0007506626592912	[323]	[1371]	7	hSpCas9	negative selection	2246381
41507810	41507833	22	+	24336569	HL60	viability	CTCTCGGAGAAGATTGTGTATGG	ACO2	ENSG00000100412	0.3254455177665472	[711]	[1887]	3	hSpCas9	negative selection	2246382
41469153	41469176	22	-	24336569	KBM7	viability	CGAGTCACCAGTAGGCTGTAGGG	ACO2	ENSG00000100412	-1.035453292689942	[495]	[659]	-6	hSpCas9	negative selection	2313550
41469161	41469184	22	+	24336569	KBM7	viability	CCTACTGGTGACTCGGCTGCAGG	ACO2	ENSG00000100412	0.8293911161321106	[175]	[852]	7	hSpCas9	negative selection	2313551
41499713	41499736	22	+	24336569	KBM7	viability	TTTCTTCTTGCAGAAAGCTCTGG	ACO2	ENSG00000100412	0.6497578049368234	[196]	[842]	6	hSpCas9	negative selection	2313552
41499778	41499801	22	-	24336569	KBM7	viability	AAAGTGGCTCATCGCCACCTTGG	ACO2	ENSG00000100412	0.8141023559016227	[488]	[2344]	7	hSpCas9	negative selection	2313553
41499804	41499827	22	-	24336569	KBM7	viability	TCATAATGGATGTACTCGTTGGG	ACO2	ENSG00000100412	-0.3435747635728952	[1009]	[2170]	-3	hSpCas9	negative selection	2313554
41499818	41499841	22	-	24336569	KBM7	viability	TCTTCTCTAGCAGGTCATAATGG	ACO2	ENSG00000100412	1.2057113789757008	[188]	[1188]	8	hSpCas9	negative selection	2313555
41499841	41499864	22	+	24336569	KBM7	viability	ACATTAACATTGTTCGCAAACGG	ACO2	ENSG00000100412	0.3168121417567088	[296]	[1008]	3	hSpCas9	negative selection	2313556
41507794	41507817	22	+	24336569	KBM7	viability	GAACCGGCCGCTGACACTCTCGG	ACO2	ENSG00000100412	-2.5427364295892225	[375]	[175]	-8	hSpCas9	negative selection	2313557
41507801	41507824	22	-	24336569	KBM7	viability	ATCTTCTCCGAGAGTGTCAGCGG	ACO2	ENSG00000100412	-0.3573125419262263	[634]	[1351]	-3	hSpCas9	negative selection	2313558
41507810	41507833	22	+	24336569	KBM7	viability	CTCTCGGAGAAGATTGTGTATGG	ACO2	ENSG00000100412	0.6894490529286308	[275]	[1213]	6	hSpCas9	negative selection	2313559
41490168	41490191	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTGGTAG	ACO2	ENSG00000100412	-0.7800023955638035	[210,54]	[8,23]	-4	dCas9-VP64	positive selection	2414188
41474568	41474591	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGCCTAG	ACO2	ENSG00000100412	-0.04533809600197003	[16,0]	[1,0]	0	dCas9-VP64	positive selection	2431152
41494686	41494709	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGCCAGG	ACO2	ENSG00000100412	-0.04533809600197003	[16,0]	[1,0]	0	dCas9-VP64	positive selection	2431237
41490168	41490191	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTGGTAG	ACO2	ENSG00000100412	7.182660032259671	[52,50]	[5183,10]	9	dCas9-VP64	positive selection	2509443
41474568	41474591	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGCCTAG	ACO2	ENSG00000100412	-1.0099528387584376	[28,142]	[9,15]	-8	dCas9-VP64	positive selection	2526407
41494686	41494709	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGCCAGG	ACO2	ENSG00000100412	-1.0099528387584376	[28,142]	[9,15]	-8	dCas9-VP64	positive selection	2526492
41469161	41469184	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	-1.2979309733146878	[3,3]	[0,0]	-9	hSpCas9	positive selection	2968505
41520215	41520238	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	-0.16436563597700787	[4,4]	[4,2]	-2	hSpCas9	positive selection	2968506
41515867	41515890	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-0.446894002281634	[3,3]	[1,2]	-6	hSpCas9	positive selection	2968507
41515400	41515423	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	-0.715472391621556	[4,4]	[1,2]	-8	hSpCas9	positive selection	2968508
41469161	41469184	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	-0.5580350441364489	[3,3]	[0,1]	-7	hSpCas9	positive selection	3036363
41520215	41520238	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	-0.15209311849140508	[4,4]	[2,2]	-2	hSpCas9	positive selection	3036364
41515867	41515890	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-0.5414280505551899	[3,3]	[2,0]	-7	hSpCas9	positive selection	3036365
41515400	41515423	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	-0.6383957699144553	[4,4]	[4,0]	-8	hSpCas9	positive selection	3036366
41522968	41522991		-	24336571	A375	resistance to PLX after 7 days	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.1657969555821171	[7,9]	[9,10]	5	hSpCas9	positive selection	3157349
41523893	41523916		-	24336571	A375	resistance to PLX after 7 days	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	0.09242234330248755	[2,3]	[2,3]	3	hSpCas9	positive selection	3157458
41522968	41522991		-	24336571	A375	resistance to PLX after 14 days	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.5176420058843179	[4,7]	[2,4]	5	hSpCas9	positive selection	3215142
41523893	41523916		-	24336571	A375	resistance to PLX after 14 days	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	0.40278830044173164	[3,2]	[1,1]	4	hSpCas9	positive selection	3215251
41522968	41522991		-	24336571	A375	viability after 7 days	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.48451015484089466	[13]	[7,9]	-6	hSpCas9	negative selection	3272935
41523893	41523916		-	24336571	A375	viability after 7 days	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.7835934615713422	[6]	[2,3]	-8	hSpCas9	negative selection	3273044
41522968	41522991		-	24336571	A375	viability after 14 days	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.9075732703080082	[13]	[4,7]	-8	hSpCas9	negative selection	3330728
41523893	41523916		-	24336571	A375	viability after 14 days	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.8147485328214652	[6]	[3,2]	-7	hSpCas9	negative selection	3330837
41522968	41522991	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.6486908817403114	[110,83]	[0,0]	3	hSpCas9	positive selection	3335263
41523893	41523916	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.2858320024596318	[188,183]	[0,0]	-2	hSpCas9	positive selection	3335264
41522943	41522966	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.20140875076830617	[162,188]	[0,0]	-1	hSpCas9	positive selection	3335265
41523920	41523943	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3354514
41525184	41525207	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.6910410201388426	[246,246]	[0,0]	-5	hSpCas9	positive selection	3354515
41525230	41525253	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3354516
41469161	41469184	22	-	26780180	HT29	viability (Avana library 4 designs)	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	4.42234441979597	[]	[]	9	hSpCas9	negative selection	3404451
41520215	41520238	22	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	2.14772588233389	[]	[]	7	hSpCas9	negative selection	3404452
41515866	41515889	22	+	26780180	HT29	viability (Avana library 4 designs)	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	5.47760827753272	[]	[]	9	hSpCas9	negative selection	3404453
41515400	41515423	22	-	26780180	HT29	viability (Avana library 4 designs)	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	5.70284875767793	[]	[]	9	hSpCas9	negative selection	3404454
41515400	41515423	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	-19.6107853613604	[]	[]	-9	hSpCas9	negative selection	3475994
41469161	41469184	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	-14.8555497359388	[]	[]	-9	hSpCas9	negative selection	3475995
41515866	41515889	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-21.3808346654106	[]	[]	-9	hSpCas9	negative selection	3475996
41520215	41520238	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	1.09303926320211	[]	[]	1	hSpCas9	negative selection	3475997
41511912	41511935	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-7.4210445292211	[]	[]	-6	hSpCas9	negative selection	3475998
41507849	41507872	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGCCAGGAAATTGAGCGAGG	ACO2	ENSG00000100412	-2.66779565166755	[]	[]	-3	hSpCas9	negative selection	3475999
41515400	41515423	22	-	26780180	A375	viability (Avana lentiGuide)	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	23.8966815137943	[]	[]	9	hSpCas9	negative selection	3584653
41469161	41469184	22	-	26780180	A375	viability (Avana lentiGuide)	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	24.8591328418706	[]	[]	9	hSpCas9	negative selection	3584654
41515866	41515889	22	+	26780180	A375	viability (Avana lentiGuide)	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	32.5384980929984	[]	[]	9	hSpCas9	negative selection	3584655
41520215	41520238	22	-	26780180	A375	viability (Avana lentiGuide)	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	11.6957088851145	[]	[]	7	hSpCas9	negative selection	3584656
41511912	41511935	22	+	26780180	A375	viability (Avana lentiGuide)	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	23.3661019394743	[]	[]	9	hSpCas9	negative selection	3584657
41507849	41507872	22	+	26780180	A375	viability (Avana lentiGuide)	GCCAGCCAGGAAATTGAGCGAGG	ACO2	ENSG00000100412	10.8966425691772	[]	[]	7	hSpCas9	negative selection	3584658
41515400	41515423	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	-1.705035874030486	[6]	[0,1]	-9	hSpCas9	positive selection	3693312
41469161	41469184	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	-0.928019066206733	[4]	[3,0]	-8	hSpCas9	positive selection	3693313
41515866	41515889	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.5241517588743216	[5]	[2,0]	-9	hSpCas9	positive selection	3693314
41520215	41520238	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	0.09869779896080899	[5]	[5,5]	2	hSpCas9	positive selection	3693315
41511912	41511935	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.010851348052033182	[5]	[5,4]	0	hSpCas9	positive selection	3693316
41507849	41507872	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGCCAGGAAATTGAGCGAGG	ACO2	ENSG00000100412	-0.017448286523219114	[3]	[4,2]	0	hSpCas9	positive selection	3693317
41515400	41515423	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCCAATCAGAAGAACACCAGGG	ACO2	ENSG00000100412	-0.6396231752860003	[6]	[2,4]	-7	hSpCas9	positive selection	3801919
41469161	41469184	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCAGCCGAGTCACCAGTAGG	ACO2	ENSG00000100412	-0.9672115532988299	[5]	[2,0]	-8	hSpCas9	positive selection	3801920
41515866	41515889	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-0.7744806036610035	[6]	[3,2]	-7	hSpCas9	positive selection	3801921
41520215	41520238	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGCCCACTTCTGCCACAGGG	ACO2	ENSG00000100412	-0.12895935636977005	[6]	[3,4]	-2	hSpCas9	positive selection	3801922
41511912	41511935	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.8768080380245629	[6]	[3,2]	-8	hSpCas9	positive selection	3801923
41507849	41507872	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGCCAGGAAATTGAGCGAGG	ACO2	ENSG00000100412	-0.5418212138402068	[4]	[2,1]	-6	hSpCas9	positive selection	3801924
41525230	41525253	22	-	26780180	A375	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.897170266393636	[]	[]	4	hSpCas9	negative selection	3910538
41522968	41522991	22	-	26780180	A375	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	1.2747611331106	[]	[]	7	hSpCas9	negative selection	3910539
41525184	41525207	22	+	26780180	A375	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	2.24536561594916	[]	[]	9	hSpCas9	negative selection	3910540
41522943	41522966	22	-	26780180	A375	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	2.2977598294303	[]	[]	9	hSpCas9	negative selection	3910541
41523893	41523916	22	-	26780180	A375	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	1.97386251794482	[]	[]	9	hSpCas9	negative selection	3910542
41523920	41523943	22	+	26780180	A375	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	1.98671464433419	[]	[]	9	hSpCas9	negative selection	3910543
41525230	41525253	22	-	26780180	HT29	viability (GeCKOv2 library)	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	1.29521401243066	[]	[]	6	hSpCas9	negative selection	4018504
41522968	41522991	22	-	26780180	HT29	viability (GeCKOv2 library)	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.757091793511169	[]	[]	3	hSpCas9	negative selection	4018505
41525184	41525207	22	+	26780180	HT29	viability (GeCKOv2 library)	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	2.88150161574442	[]	[]	9	hSpCas9	negative selection	4018506
41522943	41522966	22	-	26780180	HT29	viability (GeCKOv2 library)	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	2.96223248833248	[]	[]	9	hSpCas9	negative selection	4018507
41523893	41523916	22	-	26780180	HT29	viability (GeCKOv2 library)	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	2.61577870335901	[]	[]	9	hSpCas9	negative selection	4018508
41523920	41523943	22	+	26780180	HT29	viability (GeCKOv2 library)	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	2.61543363645347	[]	[]	9	hSpCas9	negative selection	4018509
41522968	41522991	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.2682767126130008	[2]	[2,1]	6	hSpCas9	positive selection	4184411
41523893	41523916	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.8211459824891212	[2]	[0,0]	-9	hSpCas9	positive selection	4184520
41522968	41522991	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.8608611143277074	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4248433
41523893	41523916	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.6076742641018682	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4248542
41522968	41522991	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.4803072207432899	[2]	[2,2]	8	hSpCas9	positive selection	4254167
41523893	41523916	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	0.12364150691190762	[3]	[2,2]	2	hSpCas9	positive selection	4254168
41522943	41522966	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.49864681603860495	[3]	[2,1]	-8	hSpCas9	positive selection	4254169
41523920	41523943	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.937171591703017	[3]	[1,0]	-9	hSpCas9	positive selection	4318451
41525184	41525207	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.08708353955095269	[3]	[3,2]	-2	hSpCas9	positive selection	4318452
41525230	41525253	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.13075421663551157	[2]	[2,0]	-3	hSpCas9	positive selection	4318453
41499847	41499869	22	+	27760321	OCIAML3	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-0.37405770812570505	[209,154]	[109,107]	-4	hSpCas9	negative selection	4375633
41507866	41507888	22	+	27760321	OCIAML3	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	0.4459832431708496	[534,494]	[569,520]	5	hSpCas9	negative selection	4375634
41515784	41515806	22	+	27760321	OCIAML3	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-0.4027423506611305	[842,650]	[360,539]	-4	hSpCas9	negative selection	4375635
41515867	41515889	22	+	27760321	OCIAML3	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-0.9654955247449617	[402,335]	[162,126]	-7	hSpCas9	negative selection	4375636
41517576	41517598	22	+	27760321	OCIAML3	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-0.14132164926855303	[462,490]	[337,342]	-1	hSpCas9	negative selection	4375637
41499847	41499869	22	+	27760321	OCIAML2	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-2.795291459911721	[209,154]	[30,7]	-9	hSpCas9	negative selection	4459096
41507866	41507888	22	+	27760321	OCIAML2	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-1.1762906048128428	[534,494]	[151,226]	-8	hSpCas9	negative selection	4459097
41515784	41515806	22	+	27760321	OCIAML2	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-1.5603963918886632	[842,650]	[123,307]	-8	hSpCas9	negative selection	4459098
41515867	41515889	22	+	27760321	OCIAML2	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-3.953657207541271	[402,335]	[29,4]	-9	hSpCas9	negative selection	4459099
41517576	41517598	22	+	27760321	OCIAML2	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	0.4083636721816132	[462,490]	[508,522]	5	hSpCas9	negative selection	4459100
41499847	41499869	22	+	27760321	MV411	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-0.11776475363579797	[209,154]	[89,139]	-1	hSpCas9	negative selection	4542559
41507866	41507888	22	+	27760321	MV411	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-1.2461759941397887	[534,494]	[0,356]	-7	hSpCas9	negative selection	4542560
41515784	41515806	22	+	27760321	MV411	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	0.7844355081028845	[842,650]	[710,1040]	6	hSpCas9	negative selection	4542561
41515867	41515889	22	+	27760321	MV411	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.3429709278007012	[402,335]	[0,237]	-7	hSpCas9	negative selection	4542562
41517576	41517598	22	+	27760321	MV411	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-1.305105453389695	[462,490]	[20,288]	-7	hSpCas9	negative selection	4542563
41499847	41499869	22	+	27760321	HL60	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-1.606428718360346	[209,154]	[48,47]	-8	hSpCas9	negative selection	4626022
41507866	41507888	22	+	27760321	HL60	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-1.281642319808113	[534,494]	[174,170]	-8	hSpCas9	negative selection	4626023
41515784	41515806	22	+	27760321	HL60	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-1.0013958977055084	[842,650]	[255,351]	-7	hSpCas9	negative selection	4626024
41515867	41515889	22	+	27760321	HL60	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.6376218005628649	[402,335]	[99,92]	-8	hSpCas9	negative selection	4626025
41517576	41517598	22	+	27760321	HL60	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	1.0823182337726942	[462,490]	[423,1259]	9	hSpCas9	negative selection	4626026
41499847	41499869	22	+	27760321	HT1080	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-5.780728180499988	[154,120]	[0,0]	-8	hSpCas9	negative selection	4709485
41507866	41507888	22	+	27760321	HT1080	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-6.892091447118561	[494,385]	[0,1]	-9	hSpCas9	negative selection	4709486
41515784	41515806	22	+	27760321	HT1080	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-7.244250882858732	[650,507]	[1,0]	-9	hSpCas9	negative selection	4709487
41515867	41515889	22	+	27760321	HT1080	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-6.896104309399513	[335,261]	[0,0]	-9	hSpCas9	negative selection	4709488
41517576	41517598	22	+	27760321	HT1080	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-6.837041485332979	[490,382]	[1,0]	-9	hSpCas9	negative selection	4709489
41499847	41499869	22	+	27760321	HT29	viability after 7 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-0.4256703573717622	[154,120]	[87,143,156]	-6	hSpCas9	negative selection	4792948
41507866	41507888	22	+	27760321	HT29	viability after 7 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	0.16401398201965628	[494,385]	[463,642,766]	2	hSpCas9	negative selection	4792949
41515784	41515806	22	+	27760321	HT29	viability after 7 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-0.2569158698507782	[650,507]	[745,576,565]	-4	hSpCas9	negative selection	4792950
41515867	41515889	22	+	27760321	HT29	viability after 7 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-0.02695026161722136	[335,261]	[135,585,374]	0	hSpCas9	negative selection	4792951
41517576	41517598	22	+	27760321	HT29	viability after 7 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-0.8099782466656515	[490,382]	[295,294,364]	-8	hSpCas9	negative selection	4792952
41499847	41499869	22	+	27760321	HT29	viability after 25 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-4.124763702099569	[154,120]	[14,8,1]	-9	hSpCas9	negative selection	4876411
41507866	41507888	22	+	27760321	HT29	viability after 25 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-3.1640345293004493	[494,385]	[33,51,86]	-8	hSpCas9	negative selection	4876412
41515784	41515806	22	+	27760321	HT29	viability after 25 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-3.8745937289971115	[650,507]	[99,11,16]	-9	hSpCas9	negative selection	4876413
41515867	41515889	22	+	27760321	HT29	viability after 25 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-4.589848587198183	[335,261]	[4,24,12]	-9	hSpCas9	negative selection	4876414
41517576	41517598	22	+	27760321	HT29	viability after 25 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-3.566967354702951	[490,382]	[30,62,31]	-9	hSpCas9	negative selection	4876415
41499847	41499869	22	+	27760321	HT29	viability after 22 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-3.2025969656513973	[154,120]	[14,24,11]	-8	hSpCas9	negative selection	4959874
41507866	41507888	22	+	27760321	HT29	viability after 22 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-2.8835956156140075	[494,385]	[56,114,34]	-8	hSpCas9	negative selection	4959875
41515784	41515806	22	+	27760321	HT29	viability after 22 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-3.5097385052679035	[650,507]	[15,60,100]	-9	hSpCas9	negative selection	4959876
41515867	41515889	22	+	27760321	HT29	viability after 22 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-2.6830547013650827	[335,261]	[23,111,25]	-8	hSpCas9	negative selection	4959877
41517576	41517598	22	+	27760321	HT29	viability after 22 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-3.04679276079919	[490,382]	[136,18,24]	-8	hSpCas9	negative selection	4959878
41499847	41499869	22	+	27760321	HT29	viability after 19 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-3.942733041517933	[154,120]	[27,3,0]	-9	hSpCas9	negative selection	5043337
41507866	41507888	22	+	27760321	HT29	viability after 19 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-2.663006772596296	[494,385]	[50,169,16]	-8	hSpCas9	negative selection	5043338
41515784	41515806	22	+	27760321	HT29	viability after 19 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-2.5675713983739343	[650,507]	[131,81,122]	-8	hSpCas9	negative selection	5043339
41515867	41515889	22	+	27760321	HT29	viability after 19 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-2.129096263883712	[335,261]	[26,40,157]	-8	hSpCas9	negative selection	5043340
41517576	41517598	22	+	27760321	HT29	viability after 19 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-1.959622215607442	[490,382]	[223,5,163]	-8	hSpCas9	negative selection	5043341
41499847	41499869	22	+	27760321	HT29	viability after 16 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-2.256063321614506	[154,120]	[45,41,9]	-8	hSpCas9	negative selection	5126800
41507866	41507888	22	+	27760321	HT29	viability after 16 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-2.9786460164563042	[494,385]	[31,87,63]	-9	hSpCas9	negative selection	5126801
41515784	41515806	22	+	27760321	HT29	viability after 16 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-2.738681968718489	[650,507]	[117,110,63]	-9	hSpCas9	negative selection	5126802
41515867	41515889	22	+	27760321	HT29	viability after 16 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.4048015303282486	[335,261]	[80,37,257]	-7	hSpCas9	negative selection	5126803
41517576	41517598	22	+	27760321	HT29	viability after 16 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-2.0398500717851697	[490,382]	[144,123,89]	-8	hSpCas9	negative selection	5126804
41499847	41499869	22	+	27760321	HT29	viability after 13 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-1.7837116835200106	[154,120]	[77,41,20]	-8	hSpCas9	negative selection	5210263
41507866	41507888	22	+	27760321	HT29	viability after 13 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-1.1660332737500694	[494,385]	[246,240,196]	-8	hSpCas9	negative selection	5210264
41515784	41515806	22	+	27760321	HT29	viability after 13 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-1.7513752397091802	[650,507]	[216,165,214]	-8	hSpCas9	negative selection	5210265
41515867	41515889	22	+	27760321	HT29	viability after 13 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.8951897085836629	[335,261]	[63,91,121]	-8	hSpCas9	negative selection	5210266
41517576	41517598	22	+	27760321	HT29	viability after 13 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-1.4909292232051359	[490,382]	[185,207,148]	-8	hSpCas9	negative selection	5210267
41499847	41499869	22	+	27760321	HT29	viability after 10 days	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-2.0159672932931194	[154,120]	[52,41,32]	-9	hSpCas9	negative selection	5293726
41507866	41507888	22	+	27760321	HT29	viability after 10 days	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	-0.26706779305599704	[494,385]	[331,392,639]	-3	hSpCas9	negative selection	5293727
41515784	41515806	22	+	27760321	HT29	viability after 10 days	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-0.8220892494625822	[650,507]	[479,263,477]	-7	hSpCas9	negative selection	5293728
41515867	41515889	22	+	27760321	HT29	viability after 10 days	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	-1.251397455304837	[335,261]	[141,195,133]	-8	hSpCas9	negative selection	5293729
41517576	41517598	22	+	27760321	HT29	viability after 10 days	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	-1.0387955307841112	[490,382]	[349,254,192]	-8	hSpCas9	negative selection	5293730
41499847	41499869	22	+	27760321	MOLM13	viability	ACATTGTTCGCAAACGGTAAGG	ACO2	ENSG00000100412	-1.1552835085631439	[209,154]	[81,14]	-6	hSpCas9	negative selection	5377189
41507866	41507888	22	+	27760321	MOLM13	viability	GCGAGGCAAGTCGTACCTGCGG	ACO2	ENSG00000100412	0.03139934752342283	[534,494]	[424,187]	0	hSpCas9	negative selection	5377190
41515784	41515806	22	+	27760321	MOLM13	viability	GACGGGCTCTCTCTCCGGTTGG	ACO2	ENSG00000100412	-0.366509524636965	[842,650]	[498,175]	-2	hSpCas9	negative selection	5377191
41515867	41515889	22	+	27760321	MOLM13	viability	GTGCAATCGTGGAATACCACGG	ACO2	ENSG00000100412	0.4547946981730805	[402,335]	[88,450]	3	hSpCas9	negative selection	5377192
41517576	41517598	22	+	27760321	MOLM13	viability	CGTGTTCCCTTACAACCACAGG	ACO2	ENSG00000100412	0.907733994245208	[462,490]	[604,424]	6	hSpCas9	negative selection	5377193
41469509	41469532	22	+	27661255	K562	viability	GTGAGGACAAGGTGACTAGGGGG	ACO2	ENSG00000100412	0.30301771061795824	[496,537]	[498,517]	8	dCas9-KRAB	negative selection	5460498
41469342	41469365	22	-	27661255	K562	viability	GCCGGGGACGCCTTGACCTAGGG	ACO2	ENSG00000100412	-0.09995521857259315	[1118,1307]	[1017,802]	-4	dCas9-KRAB	negative selection	5460499
41469481	41469504	22	-	27661255	K562	viability	GGAATGGAAACACACCCCACGGG	ACO2	ENSG00000100412	-0.21333139443006877	[1779,1796]	[1325,1151]	-6	dCas9-KRAB	negative selection	5460500
41469557	41469580	22	-	27661255	K562	viability	GAAGTGAGGCCTCAGGAACTGGG	ACO2	ENSG00000100412	-0.01604883230244747	[1699,1952]	[1543,1349]	0	dCas9-KRAB	negative selection	5460501
41522968	41522991	22	-	27260156	BXPC3	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.22753671531658087	[287]	[307,236,373,521]	5	hSpCas9	negative selection	5526627
41523893	41523916	22	-	27260156	BXPC3	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.042555063807706406	[658]	[647,665,559,815]	-1	hSpCas9	negative selection	5526628
41522943	41522966	22	-	27260156	BXPC3	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.2669101481270232	[765]	[583,555,755,794]	-6	hSpCas9	negative selection	5526629
41523920	41523943	22	+	27260156	BXPC3	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.2946076517408833	[489]	[417,377,422,455]	-6	hSpCas9	negative selection	5590911
41525184	41525207	22	+	27260156	BXPC3	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.29724061906508625	[824]	[552,535,750,1030]	-6	hSpCas9	negative selection	5590912
41525230	41525253	22	-	27260156	BXPC3	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.2549356936164684	[274]	[396,276,310,387]	5	hSpCas9	negative selection	5590913
41522968	41522991	22	-	27260156	A673	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.07100245004584926	[287]	[409,409,277,358]	1	hSpCas9	negative selection	5647878
41523893	41523916	22	-	27260156	A673	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.023088073270734977	[658]	[743,705,797,867]	0	hSpCas9	negative selection	5647879
41522943	41522966	22	-	27260156	A673	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.13177304534891887	[765]	[912,608,1068,773]	-3	hSpCas9	negative selection	5647880
41523920	41523943	22	+	27260156	A673	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.4038999653140846	[489]	[456,355,506,461]	-7	hSpCas9	negative selection	5712162
41525184	41525207	22	+	27260156	A673	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.31116745927157796	[824]	[695,824,727,938]	-6	hSpCas9	negative selection	5712163
41525230	41525253	22	-	27260156	A673	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.19701445594591005	[274]	[368,226,258,308]	-5	hSpCas9	negative selection	5712164
41522968	41522991	22	-	27260156	A375	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-1.0372509709317757	[287]	[197,170,222,74]	-8	hSpCas9	negative selection	5769129
41523893	41523916	22	-	27260156	A375	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.7755241032591382	[658]	[178,218,271,226]	-9	hSpCas9	negative selection	5769130
41522943	41522966	22	-	27260156	A375	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.4007301162598173	[765]	[1044,748,463,485]	-5	hSpCas9	negative selection	5769131
41523920	41523943	22	+	27260156	A375	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.0471223160381484	[489]	[134,96,106,200]	-9	hSpCas9	negative selection	5833413
41525184	41525207	22	+	27260156	A375	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.41289267273096963	[824]	[655,926,760,591]	-5	hSpCas9	negative selection	5833414
41525230	41525253	22	-	27260156	A375	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.6575090803012104	[274]	[186,237,176,214]	-7	hSpCas9	negative selection	5833415
41522968	41522991	22	-	27260156	COLO741	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.27288256661655164	[287]	[289,319,301]	-5	hSpCas9	negative selection	5890380
41523893	41523916	22	-	27260156	COLO741	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.5241544051348956	[658]	[717,557,496]	-8	hSpCas9	negative selection	5890381
41522943	41522966	22	-	27260156	COLO741	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.21545608376382447	[765]	[918,753,858]	-4	hSpCas9	negative selection	5890382
41523920	41523943	22	+	27260156	COLO741	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.4559018044863905	[489]	[329,209,157]	-9	hSpCas9	negative selection	5954664
41525184	41525207	22	+	27260156	COLO741	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.3484976996410044	[824]	[917,822,753]	-6	hSpCas9	negative selection	5954665
41525230	41525253	22	-	27260156	COLO741	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.10288890835026798	[274]	[305,344,327]	-2	hSpCas9	negative selection	5954666
41522968	41522991	22	-	27260156	CAL120	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.06409288301872851	[287]	[283,367,366]	-1	hSpCas9	negative selection	6011631
41523893	41523916	22	-	27260156	CAL120	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.1229981263737692	[658]	[611,241,311]	-9	hSpCas9	negative selection	6011632
41522943	41522966	22	-	27260156	CAL120	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	0.07878534923973046	[765]	[837,1411,748]	1	hSpCas9	negative selection	6011633
41523920	41523943	22	+	27260156	CAL120	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.3952235520228986	[489]	[111,169,65]	-9	hSpCas9	negative selection	6075915
41525184	41525207	22	+	27260156	CAL120	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.6054023467242385	[824]	[839,537,670]	-7	hSpCas9	negative selection	6075916
41525230	41525253	22	-	27260156	CAL120	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.039357550329928825	[274]	[408,363,238]	0	hSpCas9	negative selection	6075917
41522968	41522991	22	-	27260156	CADOES1	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.27939611909294015	[287]	[190,260,157,274]	-5	hSpCas9	negative selection	6132882
41523893	41523916	22	-	27260156	CADOES1	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.601618805437631	[658]	[336,498,376,402]	-8	hSpCas9	negative selection	6132883
41522943	41522966	22	-	27260156	CADOES1	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.3188509285636586	[765]	[578,579,544,580]	-5	hSpCas9	negative selection	6132884
41523920	41523943	22	+	27260156	CADOES1	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.4203552992399812	[489]	[287,399,267,408]	-6	hSpCas9	negative selection	6197166
41525184	41525207	22	+	27260156	CADOES1	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.11142109661351918	[824]	[556,761,647,880]	-2	hSpCas9	negative selection	6197167
41525230	41525253	22	-	27260156	CADOES1	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.2527142785172287	[274]	[437,286,228,262]	4	hSpCas9	negative selection	6197168
41522968	41522991	22	-	27260156	EWS502	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.391098259645807	[287]	[216,196,216,306]	-6	hSpCas9	negative selection	6254133
41523893	41523916	22	-	27260156	EWS502	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.7073994830957767	[658]	[356,470,418,470]	-8	hSpCas9	negative selection	6254134
41522943	41522966	22	-	27260156	EWS502	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.40612957714338743	[765]	[499,714,682,554]	-6	hSpCas9	negative selection	6254135
41523920	41523943	22	+	27260156	EWS502	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.0047987595096373	[489]	[180,278,276,308]	-8	hSpCas9	negative selection	6318417
41525184	41525207	22	+	27260156	EWS502	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.4013323750118497	[824]	[595,651,637,773]	-6	hSpCas9	negative selection	6318418
41525230	41525253	22	-	27260156	EWS502	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.5325123044220164	[274]	[399,273,545,477]	8	hSpCas9	negative selection	6318419
41522968	41522991	22	-	27260156	EW8	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.1705908070518899	[287]	[205,256,165,206]	-3	hSpCas9	negative selection	6375384
41523893	41523916	22	-	27260156	EW8	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.26261490261196196	[658]	[525,455,328,496]	-5	hSpCas9	negative selection	6375385
41522943	41522966	22	-	27260156	EW8	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.2922897159116022	[765]	[482,675,451,422]	-5	hSpCas9	negative selection	6375386
41523920	41523943	22	+	27260156	EW8	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.5939549054168878	[489]	[268,248,209,332]	-8	hSpCas9	negative selection	6439668
41525184	41525207	22	+	27260156	EW8	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.05919867124721767	[824]	[877,627,500,607]	-1	hSpCas9	negative selection	6439669
41525230	41525253	22	-	27260156	EW8	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.059445098754143055	[274]	[216,233,167,243]	-1	hSpCas9	negative selection	6439670
41522968	41522991	22	-	27260156	CORL105	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.7585431352303864	[287]	[150,244,270,138]	-8	hSpCas9	negative selection	6496635
41523893	41523916	22	-	27260156	CORL105	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.334948215426353	[658]	[237,304,345,337]	-9	hSpCas9	negative selection	6496636
41522943	41522966	22	-	27260156	CORL105	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.6605607715247456	[765]	[512,492,747,542]	-8	hSpCas9	negative selection	6496637
41523920	41523943	22	+	27260156	CORL105	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.2145102757951824	[489]	[313,221,186,258]	-9	hSpCas9	negative selection	6560919
41525184	41525207	22	+	27260156	CORL105	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.4520465805112568	[824]	[612,603,950,692]	-7	hSpCas9	negative selection	6560920
41525230	41525253	22	-	27260156	CORL105	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.5043467083729415	[274]	[187,243,301,183]	-7	hSpCas9	negative selection	6560921
41522968	41522991	22	-	27260156	HS294T	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.6105398104988384	[287]	[45,61,75,117]	-7	hSpCas9	negative selection	6617886
41523893	41523916	22	-	27260156	HS294T	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.3586015288250373	[658]	[259,163,158,207]	-5	hSpCas9	negative selection	6617887
41522943	41522966	22	-	27260156	HS294T	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.09017318997665658	[765]	[307,201,316,285]	-1	hSpCas9	negative selection	6617888
41523920	41523943	22	+	27260156	HS294T	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.189933199653858	[489]	[46,60,100,135]	-9	hSpCas9	negative selection	6682170
41525184	41525207	22	+	27260156	HS294T	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	0.019584644985535693	[824]	[410,323,263,276]	0	hSpCas9	negative selection	6682171
41525230	41525253	22	-	27260156	HS294T	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.4050881280751595	[274]	[144,111,131,180]	5	hSpCas9	negative selection	6682172
41522968	41522991	22	-	27260156	HCC44	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.2819716511895704	[287]	[716,170,302,433]	4	hSpCas9	negative selection	6739137
41523893	41523916	22	-	27260156	HCC44	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.6483083430446627	[658]	[506,379,689,377]	-7	hSpCas9	negative selection	6739138
41522943	41522966	22	-	27260156	HCC44	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.3033813545954912	[765]	[879,597,751,614]	-5	hSpCas9	negative selection	6739139
41523920	41523943	22	+	27260156	HCC44	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.4766723456768265	[489]	[181,145,261,220]	-9	hSpCas9	negative selection	6803421
41525184	41525207	22	+	27260156	HCC44	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.49848290918685656	[824]	[785,454,662,769]	-6	hSpCas9	negative selection	6803422
41525230	41525253	22	-	27260156	HCC44	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.000757657581243687	[274]	[284,260,243,440]	0	hSpCas9	negative selection	6803423
41522968	41522991	22	-	27260156	G402	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.12352700368700675	[287]	[86,596,433,160]	-1	hSpCas9	negative selection	6860388
41523893	41523916	22	-	27260156	G402	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.099016833301511	[658]	[197,417,528,333]	-8	hSpCas9	negative selection	6860389
41522943	41522966	22	-	27260156	G402	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.7872919902963939	[765]	[422,485,547,679]	-7	hSpCas9	negative selection	6860390
41523920	41523943	22	+	27260156	G402	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.183105400900011	[489]	[106,121,118,171]	-9	hSpCas9	negative selection	6924672
41525184	41525207	22	+	27260156	G402	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.804388280225081	[824]	[822,779,406,351]	-7	hSpCas9	negative selection	6924673
41525230	41525253	22	-	27260156	G402	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.18649885699729074	[274]	[372,312,301,206]	-2	hSpCas9	negative selection	6924674
41522968	41522991	22	-	27260156	L33	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.1891661573564951	[287]	[219,98,183,256]	-4	hSpCas9	negative selection	6981639
41523893	41523916	22	-	27260156	L33	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	0.1737994698053381	[658]	[735,293,462,782]	4	hSpCas9	negative selection	6981640
41522943	41522966	22	-	27260156	L33	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.1457387667081007	[765]	[669,305,470,604]	-3	hSpCas9	negative selection	6981641
41523920	41523943	22	+	27260156	L33	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.6221323358014059	[489]	[366,135,216,228]	-9	hSpCas9	negative selection	7045923
41525184	41525207	22	+	27260156	L33	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.11232939881698956	[824]	[799,280,544,699]	-3	hSpCas9	negative selection	7045924
41525230	41525253	22	-	27260156	L33	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.08539762247953453	[274]	[325,87,187,195]	-2	hSpCas9	negative selection	7045925
41522968	41522991	22	-	27260156	K562	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.15584610365850915	[287]	[343,353,302,159]	2	hSpCas9	negative selection	7102890
41523893	41523916	22	-	27260156	K562	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.9948150629929509	[658]	[295,329,323,231]	-8	hSpCas9	negative selection	7102891
41522943	41522966	22	-	27260156	K562	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.30831993815223613	[765]	[645,665,387,511]	-4	hSpCas9	negative selection	7102892
41523920	41523943	22	+	27260156	K562	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.2050625457596063	[489]	[126,122,389,113]	-8	hSpCas9	negative selection	7167174
41525184	41525207	22	+	27260156	K562	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.23886497897516756	[824]	[658,394,707,698]	-3	hSpCas9	negative selection	7167175
41525230	41525253	22	-	27260156	K562	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.42475846028589315	[274]	[297,193,408,390]	5	hSpCas9	negative selection	7167176
41522968	41522991	22	-	27260156	HT29	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.31006922912126544	[287]	[418,192,259,260]	-6	hSpCas9	negative selection	7224141
41523893	41523916	22	-	27260156	HT29	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.2697768773106715	[658]	[462,339,244,293]	-9	hSpCas9	negative selection	7224142
41522943	41522966	22	-	27260156	HT29	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.527033942258242	[765]	[668,757,603,569]	-7	hSpCas9	negative selection	7224143
41523920	41523943	22	+	27260156	HT29	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.395624351300765	[489]	[124,77,134,111]	-9	hSpCas9	negative selection	7288425
41525184	41525207	22	+	27260156	HT29	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.5328100831348651	[824]	[721,628,823,600]	-7	hSpCas9	negative selection	7288426
41525230	41525253	22	-	27260156	HT29	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.021221540818511464	[274]	[394,391,305,277]	0	hSpCas9	negative selection	7288427
41522968	41522991	22	-	27260156	MHHES1	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.15398328610958134	[287]	[302,331,255,276]	-3	hSpCas9	negative selection	7345392
41523893	41523916	22	-	27260156	MHHES1	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.5885845941614937	[658]	[627,449,427,472]	-8	hSpCas9	negative selection	7345393
41522943	41522966	22	-	27260156	MHHES1	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.23427667109566486	[765]	[899,747,818,521]	-4	hSpCas9	negative selection	7345394
41523920	41523943	22	+	27260156	MHHES1	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.80023771332113	[489]	[288,408,246,319]	-9	hSpCas9	negative selection	7409676
41525184	41525207	22	+	27260156	MHHES1	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.07022834318234683	[824]	[1240,998,814,588]	-1	hSpCas9	negative selection	7409677
41525230	41525253	22	-	27260156	MHHES1	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.136485784653816	[274]	[241,383,553,200]	2	hSpCas9	negative selection	7409678
41522968	41522991	22	-	27260156	MEWO	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.14596456278300007	[287]	[265,211,256]	-3	hSpCas9	negative selection	7466643
41523893	41523916	22	-	27260156	MEWO	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.5132199720808888	[658]	[581,412,329]	-8	hSpCas9	negative selection	7466644
41522943	41522966	22	-	27260156	MEWO	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.21337952529302984	[765]	[697,551,619]	-5	hSpCas9	negative selection	7466645
41523920	41523943	22	+	27260156	MEWO	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.473716233841927	[489]	[163,150,179]	-9	hSpCas9	negative selection	7530927
41525184	41525207	22	+	27260156	MEWO	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.33794421022675425	[824]	[718,572,560]	-6	hSpCas9	negative selection	7530928
41525230	41525253	22	-	27260156	MEWO	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.2345893543589066	[274]	[333,326,252]	5	hSpCas9	negative selection	7530929
41522968	41522991	22	-	27260156	LNCAPCLONEFGC	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.27802051825054275	[287]	[191,136,328,224]	-4	hSpCas9	negative selection	7587894
41523893	41523916	22	-	27260156	LNCAPCLONEFGC	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.5312893092636982	[658]	[432,316,507,413]	-7	hSpCas9	negative selection	7587895
41522943	41522966	22	-	27260156	LNCAPCLONEFGC	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.12972616798177872	[765]	[511,617,998,464]	-2	hSpCas9	negative selection	7587896
41523920	41523943	22	+	27260156	LNCAPCLONEFGC	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.8532741182564637	[489]	[270,180,269,267]	-8	hSpCas9	negative selection	7652178
41525184	41525207	22	+	27260156	LNCAPCLONEFGC	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.41622822669300974	[824]	[514,463,795,506]	-6	hSpCas9	negative selection	7652179
41525230	41525253	22	-	27260156	LNCAPCLONEFGC	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.02576606303248441	[274]	[298,228,300,192]	0	hSpCas9	negative selection	7652180
41522968	41522991	22	-	27260156	PANC0327	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.49482828645409493	[287]	[353,152,156,79]	-6	hSpCas9	negative selection	7709145
41523893	41523916	22	-	27260156	PANC0327	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.5315327458066633	[658]	[429,278,377,550]	-6	hSpCas9	negative selection	7709146
41522943	41522966	22	-	27260156	PANC0327	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.3852248122891385	[765]	[519,561,329,665]	-5	hSpCas9	negative selection	7709147
41523920	41523943	22	+	27260156	PANC0327	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.4343310604148267	[489]	[25,47,180,66]	-9	hSpCas9	negative selection	7773429
41525184	41525207	22	+	27260156	PANC0327	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.5360470804154114	[824]	[537,721,328,406]	-6	hSpCas9	negative selection	7773430
41525230	41525253	22	-	27260156	PANC0327	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.24968320219505735	[274]	[108,320,207,160]	-4	hSpCas9	negative selection	7773431
41522968	41522991	22	-	27260156	NCIH2009	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.08277778834808158	[287]	[413,387,473]	1	hSpCas9	negative selection	7830396
41523893	41523916	22	-	27260156	NCIH2009	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.2507380557835258	[658]	[825,691,813]	-3	hSpCas9	negative selection	7830397
41522943	41522966	22	-	27260156	NCIH2009	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	0.014610107509632542	[765]	[1412,976,918]	0	hSpCas9	negative selection	7830398
41523920	41523943	22	+	27260156	NCIH2009	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.2578658754643832	[489]	[318,330,213]	-8	hSpCas9	negative selection	7894680
41525184	41525207	22	+	27260156	NCIH2009	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.08902104589529414	[824]	[1477,815,1037]	-1	hSpCas9	negative selection	7894681
41525230	41525253	22	-	27260156	NCIH2009	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.19046044372661353	[274]	[443,530,338]	2	hSpCas9	negative selection	7894682
41522968	41522991	22	-	27260156	NCIH1373	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.5693190647872881	[287]	[378,711,287,130]	5	hSpCas9	negative selection	7951647
41523893	41523916	22	-	27260156	NCIH1373	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.49099799602845623	[658]	[757,231,523,173]	-5	hSpCas9	negative selection	7951648
41522943	41522966	22	-	27260156	NCIH1373	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.12794673073509888	[765]	[1005,534,1058,152]	-1	hSpCas9	negative selection	7951649
41523920	41523943	22	+	27260156	NCIH1373	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.467209579157806	[489]	[288,137,115,72]	-9	hSpCas9	negative selection	8015931
41525184	41525207	22	+	27260156	NCIH1373	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	0.00766604708760199	[824]	[1429,661,907,213]	0	hSpCas9	negative selection	8015932
41525230	41525253	22	-	27260156	NCIH1373	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.30014178788957313	[274]	[286,460,290,120]	3	hSpCas9	negative selection	8015933
41522968	41522991	22	-	27260156	PATU8902	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-1.5899693709900886	[287]	[158,107,128,136]	-8	hSpCas9	negative selection	8072898
41523893	41523916	22	-	27260156	PATU8902	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-2.186543884714533	[658]	[126,331,107,271]	-9	hSpCas9	negative selection	8072899
41522943	41522966	22	-	27260156	PATU8902	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.33500672030694767	[765]	[615,886,920,947]	-3	hSpCas9	negative selection	8072900
41523920	41523943	22	+	27260156	PATU8902	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-3.1879339071620216	[489]	[150,6,77,58]	-9	hSpCas9	negative selection	8137182
41525184	41525207	22	+	27260156	PATU8902	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.579836921805277	[824]	[934,463,1053,506]	-5	hSpCas9	negative selection	8137183
41525230	41525253	22	-	27260156	PATU8902	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.9176386868931524	[274]	[225,160,107,356]	-7	hSpCas9	negative selection	8137184
41522968	41522991	22	-	27260156	PANC1	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.23311511102467875	[287]	[223,123,290,185]	-4	hSpCas9	negative selection	8194149
41523893	41523916	22	-	27260156	PANC1	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.7876456074197352	[658]	[416,431,239,248]	-8	hSpCas9	negative selection	8194150
41522943	41522966	22	-	27260156	PANC1	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.37213733683526495	[765]	[578,554,522,394]	-5	hSpCas9	negative selection	8194151
41523920	41523943	22	+	27260156	PANC1	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.1032546058132435	[489]	[197,290,139,173]	-8	hSpCas9	negative selection	8258433
41525184	41525207	22	+	27260156	PANC1	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.24483315015644636	[824]	[666,660,563,514]	-4	hSpCas9	negative selection	8258434
41525230	41525253	22	-	27260156	PANC1	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.09469491439229938	[274]	[239,316,169,284]	1	hSpCas9	negative selection	8258435
41522968	41522991	22	-	27260156	PANC0813	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.30359018436759033	[287]	[393,280,200,232]	-5	hSpCas9	negative selection	8315400
41523893	41523916	22	-	27260156	PANC0813	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.1156456471548222	[658]	[627,321,241,265]	-8	hSpCas9	negative selection	8315401
41522943	41522966	22	-	27260156	PANC0813	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.2728409687287141	[765]	[751,578,847,796]	-4	hSpCas9	negative selection	8315402
41523920	41523943	22	+	27260156	PANC0813	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-2.0750793707570816	[489]	[147,151,91,153]	-9	hSpCas9	negative selection	8379684
41525184	41525207	22	+	27260156	PANC0813	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.375967025049095	[824]	[845,663,686,794]	-5	hSpCas9	negative selection	8379685
41525230	41525253	22	-	27260156	PANC0813	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.14827711351037542	[274]	[297,293,588,251]	2	hSpCas9	negative selection	8379686
41522968	41522991	22	-	27260156	RDES	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.3316841693767867	[287]	[183,331,230,314]	-5	hSpCas9	negative selection	8436651
41523893	41523916	22	-	27260156	RDES	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.397242850432448	[658]	[511,515,636,651]	-6	hSpCas9	negative selection	8436652
41522943	41522966	22	-	27260156	RDES	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.20257409282119954	[765]	[670,823,599,983]	-3	hSpCas9	negative selection	8436653
41523920	41523943	22	+	27260156	RDES	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.5812955371750419	[489]	[368,325,367,447]	-7	hSpCas9	negative selection	8500935
41525184	41525207	22	+	27260156	RDES	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.11816561235125111	[824]	[811,970,740,953]	-2	hSpCas9	negative selection	8500936
41525230	41525253	22	-	27260156	RDES	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.2668696886618216	[274]	[353,423,397,326]	4	hSpCas9	negative selection	8500937
41522968	41522991	22	-	27260156	PC3	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.14752521290722242	[287]	[207,394,393,314]	3	hSpCas9	negative selection	8557902
41523893	41523916	22	-	27260156	PC3	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.21900387920479458	[658]	[361,458,1001,647]	-5	hSpCas9	negative selection	8557903
41522943	41522966	22	-	27260156	PC3	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.3514989425989138	[765]	[363,691,903,591]	-7	hSpCas9	negative selection	8557904
41523920	41523943	22	+	27260156	PC3	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.5904820489112657	[489]	[79,187,242,191]	-9	hSpCas9	negative selection	8622186
41525184	41525207	22	+	27260156	PC3	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.34522528388275564	[824]	[369,651,1062,732]	-7	hSpCas9	negative selection	8622187
41525230	41525253	22	-	27260156	PC3	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.1625423049107	[274]	[83,330,658,374]	3	hSpCas9	negative selection	8622188
41522968	41522991	22	-	27260156	PATU8988T	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.4977104127548353	[287]	[173,350,114,160]	-7	hSpCas9	negative selection	8679153
41523893	41523916	22	-	27260156	PATU8988T	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.7116423144384663	[658]	[289,122,157,200]	-9	hSpCas9	negative selection	8679154
41522943	41522966	22	-	27260156	PATU8988T	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.7620100281007074	[765]	[411,515,446,372]	-8	hSpCas9	negative selection	8679155
41523920	41523943	22	+	27260156	PATU8988T	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.2260220592326292	[489]	[225,267,138,181]	-9	hSpCas9	negative selection	8743437
41525184	41525207	22	+	27260156	PATU8988T	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.6872846898017021	[824]	[443,559,500,479]	-8	hSpCas9	negative selection	8743438
41525230	41525253	22	-	27260156	PATU8988T	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.2921251827132213	[274]	[232,326,199,109]	-5	hSpCas9	negative selection	8743439
41522968	41522991	22	-	27260156	T47D	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.14203072724405008	[287]	[392,346,308,436]	3	hSpCas9	negative selection	8800404
41523893	41523916	22	-	27260156	T47D	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.18720247039911442	[658]	[733,565,624,785]	-4	hSpCas9	negative selection	8800405
41522943	41522966	22	-	27260156	T47D	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.2240077910941078	[765]	[898,736,689,732]	-5	hSpCas9	negative selection	8800406
41523920	41523943	22	+	27260156	T47D	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.7274875491871841	[489]	[279,400,341,350]	-8	hSpCas9	negative selection	8864688
41525184	41525207	22	+	27260156	T47D	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.06675371965120513	[824]	[958,858,903,954]	-1	hSpCas9	negative selection	8864689
41525230	41525253	22	-	27260156	T47D	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.013056711769131923	[274]	[365,288,295,321]	0	hSpCas9	negative selection	8864690
41522968	41522991	22	-	27260156	SU8686	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.5264532859384015	[287]	[165,206,177,250]	-7	hSpCas9	negative selection	8921655
41523893	41523916	22	-	27260156	SU8686	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-1.148571886783036	[658]	[282,259,295,352]	-9	hSpCas9	negative selection	8921656
41522943	41522966	22	-	27260156	SU8686	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.561649205424452	[765]	[586,361,451,691]	-7	hSpCas9	negative selection	8921657
41523920	41523943	22	+	27260156	SU8686	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.7692922896599759	[489]	[117,231,120,77]	-9	hSpCas9	negative selection	8985939
41525184	41525207	22	+	27260156	SU8686	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.36270667923432987	[824]	[688,599,603,645]	-6	hSpCas9	negative selection	8985940
41525230	41525253	22	-	27260156	SU8686	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.004612217485274961	[274]	[349,228,238,260]	0	hSpCas9	negative selection	8985941
41522968	41522991	22	-	27260156	SKES1	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.1313548241062007	[287]	[221,327,246,252]	-3	hSpCas9	negative selection	9042906
41523893	41523916	22	-	27260156	SKES1	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.4376450249404265	[658]	[528,460,581,378]	-7	hSpCas9	negative selection	9042907
41522943	41522966	22	-	27260156	SKES1	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.30129102610864605	[765]	[764,645,581,516]	-6	hSpCas9	negative selection	9042908
41523920	41523943	22	+	27260156	SKES1	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.8879807681781068	[489]	[284,295,235,245]	-9	hSpCas9	negative selection	9107190
41525184	41525207	22	+	27260156	SKES1	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.3592385487741892	[824]	[736,716,635,507]	-7	hSpCas9	negative selection	9107191
41525230	41525253	22	-	27260156	SKES1	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.2023250309471598	[274]	[427,295,249,300]	4	hSpCas9	negative selection	9107192
41522968	41522991	22	-	27260156	TOV112D	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	-0.08308840754094449	[287]	[399,262,189,244]	-2	hSpCas9	negative selection	9164157
41523893	41523916	22	-	27260156	TOV112D	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.11587967279025296	[658]	[462,788,631,583]	-2	hSpCas9	negative selection	9164158
41522943	41522966	22	-	27260156	TOV112D	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.5123756648759703	[765]	[562,886,411,380]	-7	hSpCas9	negative selection	9164159
41523920	41523943	22	+	27260156	TOV112D	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-1.0260698968568842	[489]	[238,241,218,262]	-9	hSpCas9	negative selection	9228441
41525184	41525207	22	+	27260156	TOV112D	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.2107209704263111	[824]	[605,1161,620,570]	-4	hSpCas9	negative selection	9228442
41525230	41525253	22	-	27260156	TOV112D	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.23825214410624163	[274]	[218,191,217,619]	4	hSpCas9	negative selection	9228443
41522968	41522991	22	-	27260156	TC71	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.006350253818178442	[287]	[325,275,330,305]	0	hSpCas9	negative selection	9285408
41523893	41523916	22	-	27260156	TC71	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.11199403864189317	[658]	[608,637,658,712]	-3	hSpCas9	negative selection	9285409
41522943	41522966	22	-	27260156	TC71	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.24626265470080572	[765]	[743,717,638,666]	-6	hSpCas9	negative selection	9285410
41523920	41523943	22	+	27260156	TC71	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.21646130426060067	[489]	[465,407,430,506]	-5	hSpCas9	negative selection	9349692
41525184	41525207	22	+	27260156	TC71	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.1320014662119332	[824]	[783,850,818,771]	-3	hSpCas9	negative selection	9349693
41525230	41525253	22	-	27260156	TC71	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	-0.11382222373501172	[274]	[260,328,281,213]	-3	hSpCas9	negative selection	9349694
41522968	41522991	22	-	27260156	TC32	viability	CACATAGCCGTCCCGCTCAATGG	ACO2	ENSG00000100412	0.0750822389703657	[287]	[207,251,377,325]	1	hSpCas9	negative selection	9406659
41523893	41523916	22	-	27260156	TC32	viability	TCTCGGGGTTTGCGTCGTTGCGG	ACO2	ENSG00000100412	-0.40832658230905805	[658]	[410,442,502,503]	-6	hSpCas9	negative selection	9406660
41522943	41522966	22	-	27260156	TC32	viability	GCGCGGATCTGCTCGGAACCTGG	ACO2	ENSG00000100412	-0.13483863794815554	[765]	[563,383,931,881]	-2	hSpCas9	negative selection	9406661
41523920	41523943	22	+	27260156	TC32	viability	TGCCTTTGTCACGTCCCCAGAGG	ACO2	ENSG00000100412	-0.8766185833130458	[489]	[170,152,348,388]	-9	hSpCas9	negative selection	9470943
41525184	41525207	22	+	27260156	TC32	viability	CTGCTGCAGGAGTTTGACCCAGG	ACO2	ENSG00000100412	-0.3022415398107444	[824]	[529,480,780,789]	-5	hSpCas9	negative selection	9470944
41525230	41525253	22	-	27260156	TC32	viability	ATGCTGCCCGCTGCTGTCCTTGG	ACO2	ENSG00000100412	0.22773809596749128	[274]	[365,186,477,222]	4	hSpCas9	negative selection	9470945
41507902	41507925	22	+	27869803	HPAFII	viability after 27 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-7.701776165703906	[395]	[0,0,NaN]	-9	hSpCas9	negative selection	9581086
41515951	41515974	22	-	27869803	HPAFII	viability after 27 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.37177394877562886	[685]	[395,180,NaN]	-3	hSpCas9	negative selection	9581087
41517610	41517633	22	+	27869803	HPAFII	viability after 27 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-5.728888011321147	[375]	[6,0,NaN]	-9	hSpCas9	negative selection	9581088
41520258	41520281	22	-	27869803	HPAFII	viability after 27 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-6.232290882402686	[272]	[2,0,NaN]	-9	hSpCas9	negative selection	9581089
41523267	41523290	22	-	27869803	HPAFII	viability after 27 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-5.049699469124213	[62]	[0,0,NaN]	-9	hSpCas9	negative selection	9581090
41524897	41524920	22	+	27869803	HPAFII	viability after 27 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-6.291588066086458	[148]	[0,0,NaN]	-9	hSpCas9	negative selection	9581091
41507902	41507925	22	+	27869803	HPAFII	viability after 15 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-4.98373978380143	[395]	[18,9,NaN]	-9	hSpCas9	negative selection	9663535
41515951	41515974	22	-	27869803	HPAFII	viability after 15 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.2964813586962953	[685]	[677,551,NaN]	-3	hSpCas9	negative selection	9663536
41517610	41517633	22	+	27869803	HPAFII	viability after 15 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-2.7641738275323595	[375]	[48,65,NaN]	-9	hSpCas9	negative selection	9663537
41520258	41520281	22	-	27869803	HPAFII	viability after 15 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-4.375605382843816	[272]	[23,7,NaN]	-9	hSpCas9	negative selection	9663538
41523267	41523290	22	-	27869803	HPAFII	viability after 15 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-2.561909687199466	[62]	[8,12,NaN]	-9	hSpCas9	negative selection	9663539
41524897	41524920	22	+	27869803	HPAFII	viability after 15 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-3.559220783035478	[148]	[28,3,NaN]	-9	hSpCas9	negative selection	9663540
41507902	41507925	22	+	27869803	ASPC1	viability after 36 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-0.6629578931733539	[870]	[153,173,230]	-6	hSpCas9	negative selection	9745984
41515951	41515974	22	-	27869803	ASPC1	viability after 36 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.021793165981130125	[1476]	[754,473,355]	0	hSpCas9	negative selection	9745985
41517610	41517633	22	+	27869803	ASPC1	viability after 36 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-0.4905339903479763	[1038]	[173,162,389]	-5	hSpCas9	negative selection	9745986
41520258	41520281	22	-	27869803	ASPC1	viability after 36 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-7.672729340528233	[586]	[0,0,0]	-9	hSpCas9	negative selection	9745987
41523267	41523290	22	-	27869803	ASPC1	viability after 36 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-0.023313232754331725	[152]	[90,73,7]	0	hSpCas9	negative selection	9745988
41524897	41524920	22	+	27869803	ASPC1	viability after 36 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-3.229769650397262	[277]	[6,0,19]	-9	hSpCas9	negative selection	9745989
41507902	41507925	22	+	27869803	PATU8988S	viability after 35 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-4.313763216583107	[739]	[8,20,NaN]	-9	hSpCas9	negative selection	9828433
41515951	41515974	22	-	27869803	PATU8988S	viability after 35 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	0.27436539120457715	[1187]	[441,715,NaN]	3	hSpCas9	negative selection	9828434
41517610	41517633	22	+	27869803	PATU8988S	viability after 35 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-4.007040955363501	[897]	[19,24,NaN]	-9	hSpCas9	negative selection	9828435
41520258	41520281	22	-	27869803	PATU8988S	viability after 35 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-7.618694561489073	[487]	[0,0,NaN]	-9	hSpCas9	negative selection	9828436
41523267	41523290	22	-	27869803	PATU8988S	viability after 35 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-5.388396942067278	[103]	[0,0,NaN]	-9	hSpCas9	negative selection	9828437
41524897	41524920	22	+	27869803	PATU8988S	viability after 35 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-2.971930157169467	[184]	[7,10,NaN]	-9	hSpCas9	negative selection	9828438
41507902	41507925	22	+	27869803	PATU8988S	viability after 31 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-5.7404356619101	[739]	[1,9,NaN]	-9	hSpCas9	negative selection	9910882
41515951	41515974	22	-	27869803	PATU8988S	viability after 31 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.07169546462544463	[1187]	[360,564,NaN]	-1	hSpCas9	negative selection	9910883
41517610	41517633	22	+	27869803	PATU8988S	viability after 31 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-4.056698947610114	[897]	[6,39,NaN]	-9	hSpCas9	negative selection	9910884
41520258	41520281	22	-	27869803	PATU8988S	viability after 31 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-3.520275323457746	[487]	[12,21,NaN]	-9	hSpCas9	negative selection	9910885
41523267	41523290	22	-	27869803	PATU8988S	viability after 31 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-2.4251682893491755	[103]	[12,0,NaN]	-9	hSpCas9	negative selection	9910886
41524897	41524920	22	+	27869803	PATU8988S	viability after 31 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-3.286510725637412	[184]	[7,6,NaN]	-9	hSpCas9	negative selection	9910887
41507902	41507925	22	+	27869803	HPAFII	viability after 35 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-7.647268067082935	[395]	[0,0,NaN]	-9	hSpCas9	negative selection	9993331
41515951	41515974	22	-	27869803	HPAFII	viability after 35 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.475812306096268	[685]	[276,218,NaN]	-3	hSpCas9	negative selection	9993332
41517610	41517633	22	+	27869803	HPAFII	viability after 35 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-7.572500298680962	[375]	[0,0,NaN]	-9	hSpCas9	negative selection	9993333
41520258	41520281	22	-	27869803	HPAFII	viability after 35 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-5.047902501234805	[272]	[6,0,NaN]	-9	hSpCas9	negative selection	9993334
41523267	41523290	22	-	27869803	HPAFII	viability after 35 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-4.995191370503242	[62]	[0,0,NaN]	-9	hSpCas9	negative selection	9993335
41524897	41524920	22	+	27869803	HPAFII	viability after 35 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-6.237079967465487	[148]	[0,0,NaN]	-9	hSpCas9	negative selection	9993336
41507902	41507925	22	+	27869803	HPAFII	viability after 31 days	TGTGGCCATGCAGGATGCGACGG	ACO2	ENSG00000100412	-7.795985420404352	[395]	[0,0,NaN]	-9	hSpCas9	negative selection	10075780
41515951	41515974	22	-	27869803	HPAFII	viability after 31 days	AGACCCATCAGGCCCAGCACAGG	ACO2	ENSG00000100412	-0.42878619882442215	[685]	[341,224,NaN]	-3	hSpCas9	negative selection	10075781
41517610	41517633	22	+	27869803	HPAFII	viability after 31 days	CTGAGCAAGACCGGCCGGGAAGG	ACO2	ENSG00000100412	-7.721217652002379	[375]	[0,0,NaN]	-9	hSpCas9	negative selection	10075782
41520258	41520281	22	-	27869803	HPAFII	viability after 31 days	TCACCCACTCGGATGTCCAGAGG	ACO2	ENSG00000100412	-3.5106180454610247	[272]	[0,26,NaN]	-9	hSpCas9	negative selection	10075783
41523267	41523290	22	-	27869803	HPAFII	viability after 31 days	ACGCCTCTTACCTGTCCCACTGG	ACO2	ENSG00000100412	-5.143908723824659	[62]	[0,0,NaN]	-9	hSpCas9	negative selection	10075784
41524897	41524920	22	+	27869803	HPAFII	viability after 31 days	GACTACCTGACGGGCACGGATGG	ACO2	ENSG00000100412	-6.385797320786904	[148]	[0,0,NaN]	-9	hSpCas9	negative selection	10075785
41523826	41523849	22	+	28162770	P31FUJ	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-0.8632287372919081	[273]	[176]	-6	hSpCas9	negative selection	10105917
41522965	41522988	22	-	28162770	P31FUJ	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-1.05885134216301	[834]	[470]	-6	hSpCas9	negative selection	10105918
41508021	41508044	22	+	28162770	P31FUJ	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-4.232802204414378	[15]	[0]	-9	hSpCas9	negative selection	10105919
41511912	41511935	22	+	28162770	P31FUJ	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	0.40759505140277574	[450]	[702]	4	hSpCas9	negative selection	10105920
41524914	41524937	22	+	28162770	P31FUJ	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-0.4931918889926088	[217]	[181]	-4	hSpCas9	negative selection	10105921
41507950	41507973	22	+	28162770	P31FUJ	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	0.4780042292849729	[255]	[418]	5	hSpCas9	negative selection	10105922
41515839	41515862	22	+	28162770	P31FUJ	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	0.3373125318994641	[292]	[434]	3	hSpCas9	negative selection	10105923
41520254	41520277	22	+	28162770	P31FUJ	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	0.6973466863316499	[200]	[382]	7	hSpCas9	negative selection	10105924
41523826	41523849	22	+	28162770	TF1	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10275283
41522965	41522988	22	-	28162770	TF1	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10275284
41508021	41508044	22	+	28162770	TF1	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10275285
41511912	41511935	22	+	28162770	TF1	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10275286
41524914	41524937	22	+	28162770	TF1	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10275287
41507950	41507973	22	+	28162770	TF1	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10275288
41515839	41515862	22	+	28162770	TF1	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10275289
41520254	41520277	22	+	28162770	TF1	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10275290
41523826	41523849	22	+	28162770	SKM1	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-2.3611605091300367	[92]	[31]	-8	hSpCas9	negative selection	10444649
41522965	41522988	22	-	28162770	SKM1	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-2.143929792909368	[179]	[71]	-8	hSpCas9	negative selection	10444650
41508021	41508044	22	+	28162770	SKM1	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.2814333166593026	[10]	[3]	-8	hSpCas9	negative selection	10444651
41511912	41511935	22	+	28162770	SKM1	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.7595376110753522	[112]	[117]	-5	hSpCas9	negative selection	10444652
41524914	41524937	22	+	28162770	SKM1	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-2.3580545982622154	[57]	[19]	-8	hSpCas9	negative selection	10444653
41507950	41507973	22	+	28162770	SKM1	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.33261685728308055	[51]	[72]	-3	hSpCas9	negative selection	10444654
41515839	41515862	22	+	28162770	SKM1	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.1231712327425705	[68]	[55]	-7	hSpCas9	negative selection	10444655
41520254	41520277	22	+	28162770	SKM1	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.4683647434073053	[35]	[22]	-7	hSpCas9	negative selection	10444656
41523826	41523849	22	+	28162770	SKM1	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-2.3611605091300367	[92]	[31]	-8	hSpCas9	negative selection	10614015
41522965	41522988	22	-	28162770	SKM1	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-2.143929792909368	[179]	[71]	-8	hSpCas9	negative selection	10614016
41508021	41508044	22	+	28162770	SKM1	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.2814333166593026	[10]	[3]	-8	hSpCas9	negative selection	10614017
41511912	41511935	22	+	28162770	SKM1	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.7595376110753522	[112]	[117]	-5	hSpCas9	negative selection	10614018
41524914	41524937	22	+	28162770	SKM1	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-2.3580545982622154	[57]	[19]	-8	hSpCas9	negative selection	10614019
41507950	41507973	22	+	28162770	SKM1	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.33261685728308055	[51]	[72]	-3	hSpCas9	negative selection	10614020
41515839	41515862	22	+	28162770	SKM1	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.1231712327425705	[68]	[55]	-7	hSpCas9	negative selection	10614021
41520254	41520277	22	+	28162770	SKM1	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.4683647434073053	[35]	[22]	-7	hSpCas9	negative selection	10614022
41523826	41523849	22	+	28162770	PL21	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.5524228347279045	[309]	[45]	-7	hSpCas9	negative selection	10783381
41522965	41522988	22	-	28162770	PL21	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-2.4354489593018043	[521]	[41]	-9	hSpCas9	negative selection	10783382
41508021	41508044	22	+	28162770	PL21	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-1.9697853869529927	[17]	[1]	-8	hSpCas9	negative selection	10783383
41511912	41511935	22	+	28162770	PL21	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	0.020815915044758215	[384]	[169]	0	hSpCas9	negative selection	10783384
41524914	41524937	22	+	28162770	PL21	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-1.5834667047956748	[240]	[34]	-7	hSpCas9	negative selection	10783385
41507950	41507973	22	+	28162770	PL21	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.8377285711011229	[192]	[46]	-5	hSpCas9	negative selection	10783386
41515839	41515862	22	+	28162770	PL21	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-0.5385025574842698	[286]	[85]	-4	hSpCas9	negative selection	10783387
41520254	41520277	22	+	28162770	PL21	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-2.279329757384522	[144]	[12]	-8	hSpCas9	negative selection	10783388
41523826	41523849	22	+	28162770	P31FUJ	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-0.8632287372919081	[273]	[176]	-6	hSpCas9	negative selection	10952747
41522965	41522988	22	-	28162770	P31FUJ	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-1.05885134216301	[834]	[470]	-6	hSpCas9	negative selection	10952748
41508021	41508044	22	+	28162770	P31FUJ	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-4.232802204414378	[15]	[0]	-9	hSpCas9	negative selection	10952749
41511912	41511935	22	+	28162770	P31FUJ	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	0.40759505140277574	[450]	[702]	4	hSpCas9	negative selection	10952750
41524914	41524937	22	+	28162770	P31FUJ	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-0.4931918889926088	[217]	[181]	-4	hSpCas9	negative selection	10952751
41507950	41507973	22	+	28162770	P31FUJ	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	0.4780042292849729	[255]	[418]	5	hSpCas9	negative selection	10952752
41515839	41515862	22	+	28162770	P31FUJ	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	0.3373125318994641	[292]	[434]	3	hSpCas9	negative selection	10952753
41520254	41520277	22	+	28162770	P31FUJ	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	0.6973466863316499	[200]	[382]	7	hSpCas9	negative selection	10952754
41523826	41523849	22	+	28162770	OCIAML5	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-3.8252996613012114	[266]	[33]	-9	hSpCas9	negative selection	11122113
41522965	41522988	22	-	28162770	OCIAML5	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-2.4891175827336074	[422]	[135]	-8	hSpCas9	negative selection	11122114
41508021	41508044	22	+	28162770	OCIAML5	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-3.6594214929216013	[13]	[1]	-9	hSpCas9	negative selection	11122115
41511912	41511935	22	+	28162770	OCIAML5	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-1.1761955739446304	[163]	[130]	-6	hSpCas9	negative selection	11122116
41524914	41524937	22	+	28162770	OCIAML5	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-4.173994665751359	[99]	[9]	-9	hSpCas9	negative selection	11122117
41507950	41507973	22	+	28162770	OCIAML5	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.9516022444149113	[119]	[111]	-5	hSpCas9	negative selection	11122118
41515839	41515862	22	+	28162770	OCIAML5	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-4.3223865056440305	[132]	[11]	-9	hSpCas9	negative selection	11122119
41520254	41520277	22	+	28162770	OCIAML5	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.575548935666581	[70]	[42]	-7	hSpCas9	negative selection	11122120
41523826	41523849	22	+	28162770	EOL1	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.6697224713768497	[621]	[102]	-8	hSpCas9	negative selection	11291479
41522965	41522988	22	-	28162770	EOL1	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-4.4144538366757695	[849]	[20]	-9	hSpCas9	negative selection	11291480
41508021	41508044	22	+	28162770	EOL1	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.162915069679805	[33]	[3]	-8	hSpCas9	negative selection	11291481
41511912	41511935	22	+	28162770	EOL1	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.47472241184999264	[727]	[275]	-4	hSpCas9	negative selection	11291482
41524914	41524937	22	+	28162770	EOL1	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-3.3550017210462757	[368]	[18]	-9	hSpCas9	negative selection	11291483
41507950	41507973	22	+	28162770	EOL1	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-1.7034834510425076	[203]	[32]	-8	hSpCas9	negative selection	11291484
41515839	41515862	22	+	28162770	EOL1	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-3.7712604978389117	[310]	[11]	-9	hSpCas9	negative selection	11291485
41520254	41520277	22	+	28162770	EOL1	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.5990141844864785	[160]	[27]	-7	hSpCas9	negative selection	11291486
41523826	41523849	22	+	28162770	MOLM13	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-0.7020356198977333	[350]	[155]	-4	hSpCas9	negative selection	11460845
41522965	41522988	22	-	28162770	MOLM13	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.497677121391547	[827]	[52]	-8	hSpCas9	negative selection	11460846
41508021	41508044	22	+	28162770	MOLM13	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-4.661393635400389	[34]	[0]	-9	hSpCas9	negative selection	11460847
41511912	41511935	22	+	28162770	MOLM13	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-2.4083044168410233	[557]	[75]	-8	hSpCas9	negative selection	11460848
41524914	41524937	22	+	28162770	MOLM13	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-4.2371669646668835	[312]	[11]	-9	hSpCas9	negative selection	11460849
41507950	41507973	22	+	28162770	MOLM13	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-2.039070607175304	[215]	[37]	-7	hSpCas9	negative selection	11460850
41515839	41515862	22	+	28162770	MOLM13	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-2.8272149252670733	[372]	[37]	-8	hSpCas9	negative selection	11460851
41520254	41520277	22	+	28162770	MOLM13	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-3.0132373081920374	[200]	[17]	-8	hSpCas9	negative selection	11460852
41523826	41523849	22	+	28162770	HEL	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.781068876906219	[439]	[81]	-7	hSpCas9	negative selection	11630211
41522965	41522988	22	-	28162770	HEL	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.903454098556224	[770]	[32]	-9	hSpCas9	negative selection	11630212
41508021	41508044	22	+	28162770	HEL	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.0202261807220725	[18]	[2]	-8	hSpCas9	negative selection	11630213
41511912	41511935	22	+	28162770	HEL	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-2.0202261807220725	[417]	[65]	-8	hSpCas9	negative selection	11630214
41524914	41524937	22	+	28162770	HEL	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-7.374069455686197	[258]	[0]	-9	hSpCas9	negative selection	11630215
41507950	41507973	22	+	28162770	HEL	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-2.5271861694419555	[188]	[20]	-8	hSpCas9	negative selection	11630216
41515839	41515862	22	+	28162770	HEL	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.7068456057898707	[315]	[61]	-7	hSpCas9	negative selection	11630217
41520254	41520277	22	+	28162770	HEL	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-0.24178395057970725	[143]	[77]	-2	hSpCas9	negative selection	11630218
41523826	41523849	22	+	28162770	MV411	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-3.683299786780111	[365]	[23]	-9	hSpCas9	negative selection	11799577
41522965	41522988	22	-	28162770	MV411	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.6711348498733782	[619]	[40]	-9	hSpCas9	negative selection	11799578
41508021	41508044	22	+	28162770	MV411	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-2.4530021673583167	[12]	[1]	-8	hSpCas9	negative selection	11799579
41511912	41511935	22	+	28162770	MV411	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-2.105854715013922	[464]	[90]	-8	hSpCas9	negative selection	11799580
41524914	41524937	22	+	28162770	MV411	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-4.083479327331841	[160]	[7]	-9	hSpCas9	negative selection	11799581
41507950	41507973	22	+	28162770	MV411	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-1.617099031922106	[192]	[52]	-7	hSpCas9	negative selection	11799582
41515839	41515862	22	+	28162770	MV411	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.8283299568351894	[214]	[50]	-8	hSpCas9	negative selection	11799583
41520254	41520277	22	+	28162770	MV411	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.7890883252423386	[159]	[38]	-8	hSpCas9	negative selection	11799584
41523826	41523849	22	+	28162770	MONOMAC1	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-1.3406277006884038	[189]	[85]	-7	hSpCas9	negative selection	11968943
41522965	41522988	22	-	28162770	MONOMAC1	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-1.280909404314574	[300]	[141]	-7	hSpCas9	negative selection	11968944
41508021	41508044	22	+	28162770	MONOMAC1	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-3.656468465696851	[10]	[0]	-9	hSpCas9	negative selection	11968945
41511912	41511935	22	+	28162770	MONOMAC1	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-1.259500934006207	[235]	[112]	-7	hSpCas9	negative selection	11968946
41524914	41524937	22	+	28162770	MONOMAC1	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-3.937277573258621	[146]	[10]	-9	hSpCas9	negative selection	11968947
41507950	41507973	22	+	28162770	MONOMAC1	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-1.7921951148865984	[141]	[46]	-8	hSpCas9	negative selection	11968948
41515839	41515862	22	+	28162770	MONOMAC1	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-0.14676364057832997	[140]	[145]	-1	hSpCas9	negative selection	11968949
41520254	41520277	22	+	28162770	MONOMAC1	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-0.6276712013894159	[61]	[45]	-5	hSpCas9	negative selection	11968950
41523826	41523849	22	+	28162770	OCIAML2	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-2.6811968111818194	[80]	[69]	-9	hSpCas9	negative selection	12138309
41522965	41522988	22	-	28162770	OCIAML2	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-4.155127999514232	[89]	[27]	-9	hSpCas9	negative selection	12138310
41508021	41508044	22	+	28162770	OCIAML2	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	-0.6632749031845577	[1]	[6]	-5	hSpCas9	negative selection	12138311
41511912	41511935	22	+	28162770	OCIAML2	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-1.7400197261157786	[90]	[150]	-8	hSpCas9	negative selection	12138312
41524914	41524937	22	+	28162770	OCIAML2	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-7.896894579944259	[42]	[0]	-9	hSpCas9	negative selection	12138313
41507950	41507973	22	+	28162770	OCIAML2	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-0.9966986369097489	[35]	[99]	-6	hSpCas9	negative selection	12138314
41515839	41515862	22	+	28162770	OCIAML2	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.3496144242807953	[39]	[86]	-7	hSpCas9	negative selection	12138315
41520254	41520277	22	+	28162770	OCIAML2	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-2.4092292805780176	[22]	[23]	-8	hSpCas9	negative selection	12138316
41523826	41523849	22	+	28162770	OCIAML3	viability	GCAGGAAGGACATCAAGAAGGGG	ACO2	ENSG00000100412	-3.163373285994301	[91]	[30]	-9	hSpCas9	negative selection	12307675
41522965	41522988	22	-	28162770	OCIAML3	viability	ATAGCCGTCCCGCTCAATGGTGG	ACO2	ENSG00000100412	-3.9235089549163265	[190]	[37]	-9	hSpCas9	negative selection	12307676
41508021	41508044	22	+	28162770	OCIAML3	viability	GGGGCGAGAAAGACCTGCGCCGG	ACO2	ENSG00000100412	0.8654239783131348	[1]	[10]	7	hSpCas9	negative selection	12307677
41511912	41511935	22	+	28162770	OCIAML3	viability	GCAGGTGCCAAATATGGCGTGGG	ACO2	ENSG00000100412	-0.8042253477145089	[117]	[203]	-5	hSpCas9	negative selection	12307678
41524914	41524937	22	+	28162770	OCIAML3	viability	GGATGGCAAGAAGTTCAGGCTGG	ACO2	ENSG00000100412	-3	[52]	[19]	-9	hSpCas9	negative selection	12307679
41507950	41507973	22	+	28162770	OCIAML3	viability	CAGCAGCGGGCTGTCCAAGGTGG	ACO2	ENSG00000100412	-1.1085808131539214	[49]	[69]	-7	hSpCas9	negative selection	12307680
41515839	41515862	22	+	28162770	OCIAML3	viability	GGCATCCTCACGGTGAAAGGTGG	ACO2	ENSG00000100412	-1.9565777197088714	[80]	[62]	-8	hSpCas9	negative selection	12307681
41520254	41520277	22	+	28162770	OCIAML3	viability	ATGGCCTCTGGACATCCGAGTGG	ACO2	ENSG00000100412	-1.2858853449618315	[41]	[51]	-7	hSpCas9	negative selection	12307682