Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 81
• Symbol: ACTN4
• Description: actinin alpha 4

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTN4

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38721554	38721577	19	+	26472758	Jiyoye	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	0.6074740319917049	[46]	[53]	4	hSpCas9	negative selection	2150
38723701	38723724	19	+	26472758	Jiyoye	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.32014004262661333	[148]	[89]	-2	hSpCas9	negative selection	2151
38647742	38647765	19	+	26472758	Jiyoye	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.09532495902330984	[50]	[35]	0	hSpCas9	negative selection	2152
38700601	38700624	19	-	26472758	Jiyoye	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	2.011634057852827	[48]	[148]	8	hSpCas9	negative selection	2153
38700614	38700637	19	+	26472758	Jiyoye	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.2861599805445074	[173]	[159]	2	hSpCas9	negative selection	2154
38701051	38701074	19	+	26472758	Jiyoye	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.937690098204653	[26]	[38]	6	hSpCas9	negative selection	2155
38714516	38714539	19	+	26472758	Jiyoye	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	1.3291728695046003	[37]	[71]	7	hSpCas9	negative selection	2156
38717112	38717135	19	-	26472758	Jiyoye	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-1.625246096186504	[224]	[54]	-8	hSpCas9	negative selection	2157
38717151	38717174	19	+	26472758	Jiyoye	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-1.1073977913238848	[39]	[13]	-6	hSpCas9	negative selection	2158
38723683	38723706	19	-	26472758	Jiyoye	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.02250889373737186	[65]	[48]	0	hSpCas9	negative selection	2159
38721554	38721577	19	+	26472758	KBM7	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-0.5794187231931746	[257,253]	[101,61]	-5	hSpCas9	negative selection	193268
38723701	38723724	19	+	26472758	KBM7	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.8599049517436044	[718,469]	[339,640]	8	hSpCas9	negative selection	193269
38647742	38647765	19	+	26472758	KBM7	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.9425987912646675	[258,211]	[245,180]	8	hSpCas9	negative selection	193270
38700601	38700624	19	-	26472758	KBM7	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.1522477944541824	[611,546]	[282,319]	1	hSpCas9	negative selection	193271
38700614	38700637	19	+	26472758	KBM7	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.08771422982056387	[734,701]	[540,197]	0	hSpCas9	negative selection	193272
38701051	38701074	19	+	26472758	KBM7	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	1.1350557267350558	[279,213]	[208,291]	9	hSpCas9	negative selection	193273
38714516	38714539	19	+	26472758	KBM7	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.5786533908476073	[346,348]	[280,213]	6	hSpCas9	negative selection	193274
38717112	38717135	19	-	26472758	KBM7	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	0.05046499748383819	[412,429]	[146,259]	0	hSpCas9	negative selection	193275
38717151	38717174	19	+	26472758	KBM7	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-2.6168412328785804	[184,292]	[21,15]	-9	hSpCas9	negative selection	193276
38723683	38723706	19	-	26472758	KBM7	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.9832346619770844	[429,265]	[406,236]	9	hSpCas9	negative selection	193277
38721554	38721577	19	+	26472758	Raji	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.1020698302553502	[73]	[7]	-7	hSpCas9	negative selection	384386
38723701	38723724	19	+	26472758	Raji	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.12954518529775838	[322]	[81]	1	hSpCas9	negative selection	384387
38647742	38647765	19	+	26472758	Raji	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.9094441577616906	[77]	[33]	8	hSpCas9	negative selection	384388
38700601	38700624	19	-	26472758	Raji	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.0008839140729206829	[266]	[61]	0	hSpCas9	negative selection	384389
38700614	38700637	19	+	26472758	Raji	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.453379390222792	[320]	[101]	4	hSpCas9	negative selection	384390
38701051	38701074	19	+	26472758	Raji	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.842575782126805	[84]	[10]	-6	hSpCas9	negative selection	384391
38714516	38714539	19	+	26472758	Raji	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	-1.1252772214166755	[187]	[19]	-7	hSpCas9	negative selection	384392
38717112	38717135	19	-	26472758	Raji	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.5497287511033919	[245]	[38]	-4	hSpCas9	negative selection	384393
38717151	38717174	19	+	26472758	Raji	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-3.05248780140479	[142]	[3]	-9	hSpCas9	negative selection	384394
38723683	38723706	19	-	26472758	Raji	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.5047190329189843	[163]	[53]	5	hSpCas9	negative selection	384395
38721554	38721577	19	+	26472758	K562	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-0.7031138524394176	[269]	[139]	-4	hSpCas9	negative selection	575504
38723701	38723724	19	+	26472758	K562	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.07220533536098822	[542]	[435]	0	hSpCas9	negative selection	575505
38647742	38647765	19	+	26472758	K562	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.15374836872638276	[196]	[184]	1	hSpCas9	negative selection	575506
38700601	38700624	19	-	26472758	K562	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.23706091498713228	[510]	[365]	-2	hSpCas9	negative selection	575507
38700614	38700637	19	+	26472758	K562	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.08161510261979876	[580]	[518]	0	hSpCas9	negative selection	575508
38701051	38701074	19	+	26472758	K562	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.3481569571645846	[189]	[125]	-2	hSpCas9	negative selection	575509
38714516	38714539	19	+	26472758	K562	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.552362593118108	[310]	[384]	4	hSpCas9	negative selection	575510
38717112	38717135	19	-	26472758	K562	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.9099094187248469	[344]	[154]	-5	hSpCas9	negative selection	575511
38717151	38717174	19	+	26472758	K562	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-5.413792755085348	[201]	[3]	-9	hSpCas9	negative selection	575512
38723683	38723706	19	-	26472758	K562	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.3174205586093535	[288]	[303]	2	hSpCas9	negative selection	575513
38647826	38647849	19	+	26627737	DLD1	viability	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.6704117396169934	[640]	[77,158,139]	-6	hSpCas9	negative selection	804564
38700658	38700681	19	+	26627737	DLD1	viability	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.16729721992515367	[1006]	[206,510,349]	1	hSpCas9	negative selection	804565
38701005	38701028	19	+	26627737	DLD1	viability	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.5397209630999312	[397]	[91,52,106]	-5	hSpCas9	negative selection	804566
38704944	38704967	19	+	26627737	DLD1	viability	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.04677921904724913	[729]	[229,250,227]	0	hSpCas9	negative selection	804567
38706047	38706070	19	-	26627737	DLD1	viability	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.9863027602074164	[385]	[104,39,39]	-7	hSpCas9	negative selection	804568
38708150	38708173	19	-	26627737	DLD1	viability	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.5819114465243791	[519]	[241,238,247]	6	hSpCas9	negative selection	804569
38647826	38647849	19	+	26627737	GBM cells	viability after 5 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.39254893927462586	[163]	[69,63]	-6	hSpCas9	negative selection	886879
38700658	38700681	19	+	26627737	GBM cells	viability after 5 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.03273953570126542	[606]	[264,400]	0	hSpCas9	negative selection	886880
38701005	38701028	19	+	26627737	GBM cells	viability after 5 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.2199635209662345	[176]	[56,105]	-3	hSpCas9	negative selection	886881
38704944	38704967	19	+	26627737	GBM cells	viability after 5 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.18466835721956276	[314]	[179,203]	3	hSpCas9	negative selection	886882
38706047	38706070	19	-	26627737	GBM cells	viability after 5 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.29123129766444583	[191]	[123,127]	4	hSpCas9	negative selection	886883
38708150	38708173	19	-	26627737	GBM cells	viability after 5 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.46836320717654994	[306]	[102,134]	-6	hSpCas9	negative selection	886884
38647826	38647849	19	+	26627737	GBM cells	viability after 13 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.10399251532238374	[163]	[84,80]	-1	hSpCas9	negative selection	969194
38700658	38700681	19	+	26627737	GBM cells	viability after 13 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	-0.44937228175415556	[606]	[222,255]	-5	hSpCas9	negative selection	969195
38701005	38701028	19	+	26627737	GBM cells	viability after 13 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.7836514453704946	[176]	[41,66]	-7	hSpCas9	negative selection	969196
38704944	38704967	19	+	26627737	GBM cells	viability after 13 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-1.0001211369095901	[314]	[85,84]	-8	hSpCas9	negative selection	969197
38706047	38706070	19	-	26627737	GBM cells	viability after 13 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.1250973503585937	[191]	[105,86]	-1	hSpCas9	negative selection	969198
38708150	38708173	19	-	26627737	GBM cells	viability after 13 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-1.0299625529167191	[306]	[53,103]	-8	hSpCas9	negative selection	969199
38647826	38647849	19	+	26627737	GBM cells	viability after 21 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-1.116642291927904	[163]	[38,42]	-7	hSpCas9	negative selection	1051509
38700658	38700681	19	+	26627737	GBM cells	viability after 21 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	-1.4071211656956524	[606]	[127,120]	-8	hSpCas9	negative selection	1051510
38701005	38701028	19	+	26627737	GBM cells	viability after 21 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.3164280842987814	[176]	[35,40]	-8	hSpCas9	negative selection	1051511
38704944	38704967	19	+	26627737	GBM cells	viability after 21 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-1.6107613051439715	[314]	[66,45]	-8	hSpCas9	negative selection	1051512
38706047	38706070	19	-	26627737	GBM cells	viability after 21 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-1.4304675398484499	[191]	[33,42]	-8	hSpCas9	negative selection	1051513
38708150	38708173	19	-	26627737	GBM cells	viability after 21 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-2.1063577879585105	[306]	[44,32]	-9	hSpCas9	negative selection	1051514
38647826	38647849	19	+	26627737	RPE1	viability after 9 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.9174517246776202	[474]	[100,49]	-6	hSpCas9	negative selection	1133824
38700658	38700681	19	+	26627737	RPE1	viability after 9 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	1.5223172039692454	[733]	[639,685]	8	hSpCas9	negative selection	1133825
38701005	38701028	19	+	26627737	RPE1	viability after 9 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.2497844623563292	[993]	[153,100]	-7	hSpCas9	negative selection	1133826
38704944	38704967	19	+	26627737	RPE1	viability after 9 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.5616807132394015	[442]	[212,193]	4	hSpCas9	negative selection	1133827
38706047	38706070	19	-	26627737	RPE1	viability after 9 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	1.415468248036857	[177]	[35,293]	7	hSpCas9	negative selection	1133828
38708150	38708173	19	-	26627737	RPE1	viability after 9 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-1.4576319904040327	[1634]	[150,231]	-8	hSpCas9	negative selection	1133829
38647826	38647849	19	+	26627737	RPE1	viability after 12 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.7150340672404603	[474]	[102,50]	-5	hSpCas9	negative selection	1216139
38700658	38700681	19	+	26627737	RPE1	viability after 12 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	1.3308376687493713	[733]	[531,457]	7	hSpCas9	negative selection	1216140
38701005	38701028	19	+	26627737	RPE1	viability after 12 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.38937374691381	[993]	[99,103]	-7	hSpCas9	negative selection	1216141
38704944	38704967	19	+	26627737	RPE1	viability after 12 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.3263284945454102	[442]	[122,176]	2	hSpCas9	negative selection	1216142
38706047	38706070	19	-	26627737	RPE1	viability after 12 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	1.3113804646064213	[177]	[124,111]	7	hSpCas9	negative selection	1216143
38708150	38708173	19	-	26627737	RPE1	viability after 12 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-1.494354197284631	[1634]	[152,158]	-7	hSpCas9	negative selection	1216144
38647826	38647849	19	+	26627737	RPE1	viability after 15 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-1.3170223320068764	[474]	[85,22]	-7	hSpCas9	negative selection	1298454
38700658	38700681	19	+	26627737	RPE1	viability after 15 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.9178379493628737	[733]	[432,352]	5	hSpCas9	negative selection	1298455
38701005	38701028	19	+	26627737	RPE1	viability after 15 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.7990940177716142	[993]	[63,96]	-8	hSpCas9	negative selection	1298456
38704944	38704967	19	+	26627737	RPE1	viability after 15 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.4668924123264653	[442]	[189,156]	3	hSpCas9	negative selection	1298457
38706047	38706070	19	-	26627737	RPE1	viability after 15 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.02610045267539407	[177]	[35,65]	0	hSpCas9	negative selection	1298458
38708150	38708173	19	-	26627737	RPE1	viability after 15 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-1.5861792373585701	[1634]	[179,128]	-7	hSpCas9	negative selection	1298459
38647826	38647849	19	+	26627737	RPE1	viability after 18 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-1.5536027492205418	[474]	[33,53]	-7	hSpCas9	negative selection	1380769
38700658	38700681	19	+	26627737	RPE1	viability after 18 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	1.338084530425055	[733]	[581,413]	7	hSpCas9	negative selection	1380770
38701005	38701028	19	+	26627737	RPE1	viability after 18 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-3.041388971981982	[993]	[34,29]	-9	hSpCas9	negative selection	1380771
38704944	38704967	19	+	26627737	RPE1	viability after 18 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.8046208009281282	[442]	[188,229]	5	hSpCas9	negative selection	1380772
38706047	38706070	19	-	26627737	RPE1	viability after 18 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.8569569138454587	[177]	[57,117]	5	hSpCas9	negative selection	1380773
38708150	38708173	19	-	26627737	RPE1	viability after 18 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-2.5265448337690595	[1634]	[107,42]	-8	hSpCas9	negative selection	1380774
38647826	38647849	19	+	26627737	HeLa	viability after 8 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.7381249741672256	[244]	[162,215,152]	6	hSpCas9	negative selection	1463084
38700658	38700681	19	+	26627737	HeLa	viability after 8 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.31038990658662124	[784]	[428,390,449]	3	hSpCas9	negative selection	1463085
38701005	38701028	19	+	26627737	HeLa	viability after 8 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.22635514907731952	[374]	[188,80,157]	-2	hSpCas9	negative selection	1463086
38704944	38704967	19	+	26627737	HeLa	viability after 8 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.40961369849881213	[691]	[164,326,177]	-4	hSpCas9	negative selection	1463087
38706047	38706070	19	-	26627737	HeLa	viability after 8 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.2657340680691036	[389]	[176,107,145]	-3	hSpCas9	negative selection	1463088
38708150	38708173	19	-	26627737	HeLa	viability after 8 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.3381158205096676	[388]	[219,264,161]	3	hSpCas9	negative selection	1463089
38647826	38647849	19	+	26627737	HeLa	viability after 12 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.9761041811313661	[244]	[250,189,158]	7	hSpCas9	negative selection	1545399
38700658	38700681	19	+	26627737	HeLa	viability after 12 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.20498303181942734	[784]	[413,203,522]	1	hSpCas9	negative selection	1545400
38701005	38701028	19	+	26627737	HeLa	viability after 12 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.15983927264084907	[374]	[108,150,153]	-1	hSpCas9	negative selection	1545401
38704944	38704967	19	+	26627737	HeLa	viability after 12 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-1.3905172161254569	[691]	[158,58,115]	-8	hSpCas9	negative selection	1545402
38706047	38706070	19	-	26627737	HeLa	viability after 12 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.3920387217006828	[389]	[220,114,308]	3	hSpCas9	negative selection	1545403
38708150	38708173	19	-	26627737	HeLa	viability after 12 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.1552100302196001	[388]	[213,141,185]	1	hSpCas9	negative selection	1545404
38647826	38647849	19	+	26627737	HeLa	viability after 15 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.8749376846437344	[244]	[277,104,162]	6	hSpCas9	negative selection	1627714
38700658	38700681	19	+	26627737	HeLa	viability after 15 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.38137342899887405	[784]	[460,228,569]	3	hSpCas9	negative selection	1627715
38701005	38701028	19	+	26627737	HeLa	viability after 15 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.4363838092008538	[374]	[15,170,155]	-4	hSpCas9	negative selection	1627716
38704944	38704967	19	+	26627737	HeLa	viability after 15 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.8644352219267128	[691]	[133,108,226]	-6	hSpCas9	negative selection	1627717
38706047	38706070	19	-	26627737	HeLa	viability after 15 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.28304802127805534	[389]	[111,60,225]	-2	hSpCas9	negative selection	1627718
38708150	38708173	19	-	26627737	HeLa	viability after 15 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.2323988531853824	[388]	[146,39,386]	2	hSpCas9	negative selection	1627719
38647826	38647849	19	+	26627737	HeLa	viability after 18 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.8582855738346	[244]	[179,89,162]	6	hSpCas9	negative selection	1710029
38700658	38700681	19	+	26627737	HeLa	viability after 18 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.38881892177776967	[784]	[313,188,569]	3	hSpCas9	negative selection	1710030
38701005	38701028	19	+	26627737	HeLa	viability after 18 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.37593141352040527	[374]	[14,147,155]	-3	hSpCas9	negative selection	1710031
38704944	38704967	19	+	26627737	HeLa	viability after 18 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.8196658329666676	[691]	[97,91,226]	-6	hSpCas9	negative selection	1710032
38706047	38706070	19	-	26627737	HeLa	viability after 18 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.33016846490036794	[389]	[68,47,225]	-3	hSpCas9	negative selection	1710033
38708150	38708173	19	-	26627737	HeLa	viability after 18 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.21422910773810205	[388]	[94,31,386]	1	hSpCas9	negative selection	1710034
38647826	38647849	19	+	26627737	HCT116	viability after 6 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.4531705197314242	[244]	[73,40]	2	hSpCas9	negative selection	1792344
38700658	38700681	19	+	26627737	HCT116	viability after 6 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	1.0089623541636557	[1076]	[332,344]	5	hSpCas9	negative selection	1792345
38701005	38701028	19	+	26627737	HCT116	viability after 6 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.4793519443455223	[270]	[7,42]	-3	hSpCas9	negative selection	1792346
38704944	38704967	19	+	26627737	HCT116	viability after 6 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.6780578555306556	[990]	[120,319]	4	hSpCas9	negative selection	1792347
38706047	38706070	19	-	26627737	HCT116	viability after 6 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.9584282108507256	[535]	[262,108]	5	hSpCas9	negative selection	1792348
38708150	38708173	19	-	26627737	HCT116	viability after 6 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.12255836467511685	[600]	[167,41]	0	hSpCas9	negative selection	1792349
38647826	38647849	19	+	26627737	HCT116	viability after 8 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.37734615224636225	[324]	[98,100,211]	-4	hSpCas9	negative selection	1874659
38700658	38700681	19	+	26627737	HCT116	viability after 8 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.5723567154879389	[483]	[313,376,495]	6	hSpCas9	negative selection	1874660
38701005	38701028	19	+	26627737	HCT116	viability after 8 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.1922894681163307	[327]	[42,144,48]	-9	hSpCas9	negative selection	1874661
38704944	38704967	19	+	26627737	HCT116	viability after 8 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.13467209562633115	[324]	[157,223,206]	1	hSpCas9	negative selection	1874662
38706047	38706070	19	-	26627737	HCT116	viability after 8 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	1.3542267487746507	[158]	[257,224,189]	9	hSpCas9	negative selection	1874663
38708150	38708173	19	-	26627737	HCT116	viability after 8 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.3792867501525807	[290]	[273,237,115]	4	hSpCas9	negative selection	1874664
38647826	38647849	19	+	26627737	HCT116	viability after 9 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	2.4890855682570923	[244]	[335,391]	9	hSpCas9	negative selection	1956974
38700658	38700681	19	+	26627737	HCT116	viability after 9 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.508843259134854	[1076]	[454,372]	4	hSpCas9	negative selection	1956975
38701005	38701028	19	+	26627737	HCT116	viability after 9 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	0.12068652849341288	[270]	[76,79]	0	hSpCas9	negative selection	1956976
38704944	38704967	19	+	26627737	HCT116	viability after 9 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.6311916244567302	[990]	[281,82]	-4	hSpCas9	negative selection	1956977
38706047	38706070	19	-	26627737	HCT116	viability after 9 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-1.240196693123061	[535]	[116,15]	-7	hSpCas9	negative selection	1956978
38708150	38708173	19	-	26627737	HCT116	viability after 9 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	1.2998064805590044	[600]	[460,342]	8	hSpCas9	negative selection	1956979
38647826	38647849	19	+	26627737	HCT116	viability after 12 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.414220105659466	[324]	[325,179,166]	4	hSpCas9	negative selection	2039289
38700658	38700681	19	+	26627737	HCT116	viability after 12 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.7291694517149817	[483]	[425,481,357]	6	hSpCas9	negative selection	2039290
38701005	38701028	19	+	26627737	HCT116	viability after 12 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.2592457822621554	[327]	[78,95,40]	-8	hSpCas9	negative selection	2039291
38704944	38704967	19	+	26627737	HCT116	viability after 12 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.09794836393589457	[324]	[235,235,72]	1	hSpCas9	negative selection	2039292
38706047	38706070	19	-	26627737	HCT116	viability after 12 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	1.4413090152225234	[158]	[223,308,149]	9	hSpCas9	negative selection	2039293
38708150	38708173	19	-	26627737	HCT116	viability after 12 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.8600996167748673	[290]	[268,255,307]	7	hSpCas9	negative selection	2039294
38647826	38647849	19	+	26627737	HCT116	viability after 15 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.2617089221412584	[324]	[222,159,92]	-3	hSpCas9	negative selection	2121604
38700658	38700681	19	+	26627737	HCT116	viability after 15 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.7780893978681486	[483]	[303,547,555]	6	hSpCas9	negative selection	2121605
38701005	38701028	19	+	26627737	HCT116	viability after 15 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.6762614284723332	[327]	[171,134,53]	-6	hSpCas9	negative selection	2121606
38704944	38704967	19	+	26627737	HCT116	viability after 15 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.31063230216450566	[324]	[352,269,87]	3	hSpCas9	negative selection	2121607
38706047	38706070	19	-	26627737	HCT116	viability after 15 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	1.000321399197181	[158]	[226,193,132]	8	hSpCas9	negative selection	2121608
38708150	38708173	19	-	26627737	HCT116	viability after 15 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.7541067787909201	[290]	[295,243,306]	6	hSpCas9	negative selection	2121609
38647826	38647849	19	+	26627737	HCT116	viability after 18 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.43816516936430855	[324]	[78,155,109]	-4	hSpCas9	negative selection	2203919
38700658	38700681	19	+	26627737	HCT116	viability after 18 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.8679077839428121	[483]	[254,412,622]	7	hSpCas9	negative selection	2203920
38701005	38701028	19	+	26627737	HCT116	viability after 18 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.2499085830818948	[327]	[65,109,18]	-8	hSpCas9	negative selection	2203921
38704944	38704967	19	+	26627737	HCT116	viability after 18 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.9676749611107802	[324]	[440,310,162]	7	hSpCas9	negative selection	2203922
38706047	38706070	19	-	26627737	HCT116	viability after 18 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.6351115147998483	[158]	[142,50,170]	5	hSpCas9	negative selection	2203923
38708150	38708173	19	-	26627737	HCT116	viability after 18 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.5560702669002439	[290]	[162,314,131]	5	hSpCas9	negative selection	2203924
38647742	38647765	19	+	24336569	HL60	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.1826433398701237	[447]	[1075]	1	hSpCas9	negative selection	2246463
38647757	38647780	19	-	24336569	HL60	viability	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	0.08103426523861715	[540]	[1210]	0	hSpCas9	negative selection	2246464
38647764	38647787	19	+	24336569	HL60	viability	GCGAACCAGTCGTACCAGTACGG	ACTN4	ENSG00000130402	0.5302002851052754	[570]	[1744]	5	hSpCas9	negative selection	2246465
38647788	38647811	19	-	24336569	HL60	viability	GCGCCATTGCCCGCGCTGCTGGG	ACTN4	ENSG00000130402	1.3327680985783044	[111]	[596]	8	hSpCas9	negative selection	2246466
38647794	38647817	19	+	24336569	HL60	viability	AGCGCGGGCAATGGCGCTGGCGG	ACTN4	ENSG00000130402	0.38040656345981827	[590]	[1627]	3	hSpCas9	negative selection	2246467
38647820	38647843	19	+	24336569	HL60	viability	GGGCAGCATGGGCGACTACATGG	ACTN4	ENSG00000130402	-0.25863418436430874	[1072]	[1897]	-2	hSpCas9	negative selection	2246468
38647826	38647849	19	+	24336569	HL60	viability	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.5085639899655385	[1160]	[1726]	-4	hSpCas9	negative selection	2246469
38647837	38647860	19	+	24336569	HL60	viability	ACATGGCCCAGGAGGACGACTGG	ACTN4	ENSG00000130402	1.367247487700276	[306]	[1675]	8	hSpCas9	negative selection	2246470
38647843	38647866	19	+	24336569	HL60	viability	CCCAGGAGGACGACTGGGACCGG	ACTN4	ENSG00000130402	0.36604669635421583	[927]	[2530]	3	hSpCas9	negative selection	2246471
38647885	38647908	19	-	24336569	HL60	viability	CTTGCGCTGCTGCTTCTCCCAGG	ACTN4	ENSG00000130402	0.35910849075708495	[146]	[398]	3	hSpCas9	negative selection	2246472
38647742	38647765	19	+	24336569	KBM7	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.5674125736948106	[358]	[1450]	5	hSpCas9	negative selection	2313640
38647757	38647780	19	-	24336569	KBM7	viability	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	0.6623523863628359	[400]	[1730]	6	hSpCas9	negative selection	2313641
38647764	38647787	19	+	24336569	KBM7	viability	GCGAACCAGTCGTACCAGTACGG	ACTN4	ENSG00000130402	0.3046277832014588	[837]	[2822]	3	hSpCas9	negative selection	2313642
38647788	38647811	19	-	24336569	KBM7	viability	GCGCCATTGCCCGCGCTGCTGGG	ACTN4	ENSG00000130402	0.6020515711757183	[149]	[620]	5	hSpCas9	negative selection	2313643
38647794	38647817	19	+	24336569	KBM7	viability	AGCGCGGGCAATGGCGCTGGCGG	ACTN4	ENSG00000130402	0.3864850857224049	[473]	[1689]	3	hSpCas9	negative selection	2313644
38647820	38647843	19	+	24336569	KBM7	viability	GGGCAGCATGGGCGACTACATGG	ACTN4	ENSG00000130402	-0.1468694673666242	[1136]	[2800]	-1	hSpCas9	negative selection	2313645
38647826	38647849	19	+	24336569	KBM7	viability	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.4228057041157026	[610]	[2233]	4	hSpCas9	negative selection	2313646
38647837	38647860	19	+	24336569	KBM7	viability	ACATGGCCCAGGAGGACGACTGG	ACTN4	ENSG00000130402	1.2207390506677536	[268]	[1709]	8	hSpCas9	negative selection	2313647
38647843	38647866	19	+	24336569	KBM7	viability	CCCAGGAGGACGACTGGGACCGG	ACTN4	ENSG00000130402	0.9025687719859381	[566]	[2890]	7	hSpCas9	negative selection	2313648
38647885	38647908	19	-	24336569	KBM7	viability	CTTGCGCTGCTGCTTCTCCCAGG	ACTN4	ENSG00000130402	-1.867910995497239	[90]	[67]	-8	hSpCas9	negative selection	2313649
38726069	38726092	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTTGAACTCCTGGGCTCAAG	ACTN4	ENSG00000130402	4.2770735618878515	[141,50]	[775,15]	9	dCas9-VP64	positive selection	2397356
38718297	38718320	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCAAG	ACTN4	ENSG00000130402	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469710
38726069	38726092	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTTGAACTCCTGGGCTCAAG	ACTN4	ENSG00000130402	0.8672449668792414	[148,204]	[104,104]	6	dCas9-VP64	positive selection	2492611
38718297	38718320	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCAAG	ACTN4	ENSG00000130402	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2564965
38647743	38647766	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.02768587432194969	[4,4]	[5,2]	0	hSpCas9	positive selection	2968734
38704961	38704984	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	0.17655477044612422	[4,4]	[4,4]	4	hSpCas9	positive selection	2968735
38717957	38717980	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	-0.14989014916693955	[2,2]	[1,2]	-2	hSpCas9	positive selection	2968736
38647757	38647780	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	0.2781262557780563	[3,3]	[3,3]	6	hSpCas9	positive selection	2968737
38647743	38647766	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.2626309199456091	[4,4]	[2,4]	4	hSpCas9	positive selection	3036592
38704961	38704984	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	0.2955256435338613	[4,4]	[4,3]	5	hSpCas9	positive selection	3036593
38717957	38717980	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	-0.7633163381401167	[2,2]	[1,0]	-8	hSpCas9	positive selection	3036594
38647757	38647780	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	0.09907900791566109	[3,3]	[3,1]	1	hSpCas9	positive selection	3036595
38701000	38701023		+	24336571	A375	resistance to PLX after 7 days	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	0.04390143327081375	[6,7]	[5,8]	1	hSpCas9	positive selection	3159959
38700671	38700694		-	24336571	A375	resistance to PLX after 7 days	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.2853687665677782	[14,14]	[17,18]	7	hSpCas9	positive selection	3159968
38701081	38701104		+	24336571	A375	resistance to PLX after 7 days	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	0.2575578189493461	[13,13]	[15,17]	7	hSpCas9	positive selection	3159974
38701000	38701023		+	24336571	A375	resistance to PLX after 14 days	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	-0.17308082789216095	[3,5]	[1,1]	-2	hSpCas9	positive selection	3217752
38700671	38700694		-	24336571	A375	resistance to PLX after 14 days	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.3820009055771387	[18,24]	[13,11]	4	hSpCas9	positive selection	3217761
38701081	38701104		+	24336571	A375	resistance to PLX after 14 days	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	0.8178429904111197	[13,16]	[12,11]	7	hSpCas9	positive selection	3217767
38701000	38701023		+	24336571	A375	viability after 7 days	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	0.10128538224695283	[6]	[6,7]	1	hSpCas9	negative selection	3275545
38700671	38700694		-	24336571	A375	viability after 7 days	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.06453575841806819	[16]	[14,14]	-1	hSpCas9	negative selection	3275554
38701081	38701104		+	24336571	A375	viability after 7 days	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	0.24455476247675395	[11]	[13,13]	4	hSpCas9	negative selection	3275560
38701000	38701023		+	24336571	A375	viability after 14 days	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	-0.34225895668220596	[6]	[3,5]	-4	hSpCas9	negative selection	3333338
38700671	38700694		-	24336571	A375	viability after 14 days	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.4544964121127307	[16]	[18,24]	6	hSpCas9	negative selection	3333347
38701081	38701104		+	24336571	A375	viability after 14 days	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	0.38122224063241633	[11]	[13,16]	5	hSpCas9	negative selection	3333353
38700671	38700694	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.9028418235425233	[294,276]	[0,0]	-6	hSpCas9	positive selection	3335428
38700601	38700624	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.9733753961676606	[65,89]	[0,0]	4	hSpCas9	positive selection	3335429
38706094	38706117	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	3.1715283386906057	[13,19]	[0,0]	8	hSpCas9	positive selection	3335430
38701051	38701074	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	6.206700138375867	[57,57]	[27,27]	9	hSpCas9	positive selection	3354678
38701019	38701042	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-1.2102793386371622	[353,353]	[0,0]	-7	hSpCas9	positive selection	3354679
38704983	38705006	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	-0.40088527130595963	[403,403]	[1,1]	-3	hSpCas9	positive selection	3354680
38647742	38647765	19	+	26780180	HT29	viability (Avana library 4 designs)	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.857747794427729	[]	[]	3	hSpCas9	negative selection	3404682
38704961	38704984	19	-	26780180	HT29	viability (Avana library 4 designs)	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	0.470376893974178	[]	[]	1	hSpCas9	negative selection	3404683
38717956	38717979	19	+	26780180	HT29	viability (Avana library 4 designs)	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	1.57775426867922	[]	[]	6	hSpCas9	negative selection	3404684
38647757	38647780	19	-	26780180	HT29	viability (Avana library 4 designs)	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	1.21831675951189	[]	[]	5	hSpCas9	negative selection	3404685
38647742	38647765	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	8.44375098300397	[]	[]	9	hSpCas9	negative selection	3476339
38647757	38647780	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	6.47587997657901	[]	[]	9	hSpCas9	negative selection	3476340
38704961	38704984	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	2.92947959856021	[]	[]	4	hSpCas9	negative selection	3476341
38717956	38717979	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	6.31492664732949	[]	[]	9	hSpCas9	negative selection	3476342
38701008	38701031	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTACCTAAGCCGGAGCGGGGG	ACTN4	ENSG00000130402	4.89683233671916	[]	[]	8	hSpCas9	negative selection	3476343
38704924	38704947	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTGTGCAGAGATTGTGGACGG	ACTN4	ENSG00000130402	5.57473753422783	[]	[]	8	hSpCas9	negative selection	3476344
38647742	38647765	19	+	26780180	A375	viability (Avana lentiGuide)	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-3.8352038955859	[]	[]	-6	hSpCas9	negative selection	3584998
38647757	38647780	19	-	26780180	A375	viability (Avana lentiGuide)	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	-0.853864543382188	[]	[]	-1	hSpCas9	negative selection	3584999
38704961	38704984	19	-	26780180	A375	viability (Avana lentiGuide)	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	-1.9996667825304	[]	[]	-3	hSpCas9	negative selection	3585000
38717956	38717979	19	+	26780180	A375	viability (Avana lentiGuide)	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	0.221733030995242	[]	[]	0	hSpCas9	negative selection	3585001
38701008	38701031	19	+	26780180	A375	viability (Avana lentiGuide)	GGTTACCTAAGCCGGAGCGGGGG	ACTN4	ENSG00000130402	1.90887463202437	[]	[]	2	hSpCas9	negative selection	3585002
38704924	38704947	19	+	26780180	A375	viability (Avana lentiGuide)	CTGTGTGCAGAGATTGTGGACGG	ACTN4	ENSG00000130402	-10.9601001447778	[]	[]	-9	hSpCas9	negative selection	3585003
38647742	38647765	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.4670834054032686	[5]	[7,7]	9	hSpCas9	positive selection	3693657
38647757	38647780	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	0.3383114358021059	[4]	[5,4]	8	hSpCas9	positive selection	3693658
38704961	38704984	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	0.13036488697570597	[6]	[7,6]	3	hSpCas9	positive selection	3693659
38717956	38717979	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	0.6148034556953984	[4]	[7,6]	9	hSpCas9	positive selection	3693660
38701008	38701031	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTACCTAAGCCGGAGCGGGGG	ACTN4	ENSG00000130402	0.5436546540646121	[5]	[7,8]	9	hSpCas9	positive selection	3693661
38704924	38704947	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTGTGCAGAGATTGTGGACGG	ACTN4	ENSG00000130402	0.45497111382705435	[5]	[6,7]	9	hSpCas9	positive selection	3693662
38647742	38647765	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.37570289405200774	[6]	[7,7]	9	hSpCas9	positive selection	3802264
38647757	38647780	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTACGACTGGTTCGCCGCGTGG	ACTN4	ENSG00000130402	-0.2043242086644439	[5]	[3,3]	-3	hSpCas9	positive selection	3802265
38704961	38704984	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGTCCAGATCATTCCCAGGG	ACTN4	ENSG00000130402	0.4782253445357323	[6]	[7,8]	9	hSpCas9	positive selection	3802266
38717956	38717979	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGCTGAGAAGGGCTACGAGG	ACTN4	ENSG00000130402	0.5437872330406535	[4]	[6,6]	9	hSpCas9	positive selection	3802267
38701008	38701031	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTACCTAAGCCGGAGCGGGGG	ACTN4	ENSG00000130402	0.5382255008169863	[6]	[7,8]	9	hSpCas9	positive selection	3802268
38704924	38704947	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTGTGCAGAGATTGTGGACGG	ACTN4	ENSG00000130402	0.6938221796238657	[5]	[7,7]	9	hSpCas9	positive selection	3802269
38701019	38701042	19	-	26780180	A375	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.334418740050821	[]	[]	0	hSpCas9	negative selection	3910871
38701051	38701074	19	+	26780180	A375	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	1.27753059906012	[]	[]	7	hSpCas9	negative selection	3910872
38704983	38705006	19	+	26780180	A375	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.710875143721719	[]	[]	2	hSpCas9	negative selection	3910873
38700671	38700694	19	-	26780180	A375	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.802250367285331	[]	[]	3	hSpCas9	negative selection	3910874
38700601	38700624	19	-	26780180	A375	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.348483262507665	[]	[]	0	hSpCas9	negative selection	3910875
38706094	38706117	19	-	26780180	A375	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.214606903054955	[]	[]	0	hSpCas9	negative selection	3910876
38701019	38701042	19	-	26780180	HT29	viability (GeCKOv2 library)	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	1.50294213335353	[]	[]	7	hSpCas9	negative selection	4018837
38701051	38701074	19	+	26780180	HT29	viability (GeCKOv2 library)	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	2.08536909548445	[]	[]	9	hSpCas9	negative selection	4018838
38704983	38705006	19	+	26780180	HT29	viability (GeCKOv2 library)	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	1.33775990819635	[]	[]	6	hSpCas9	negative selection	4018839
38700671	38700694	19	-	26780180	HT29	viability (GeCKOv2 library)	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	1.23435485768644	[]	[]	6	hSpCas9	negative selection	4018840
38700601	38700624	19	-	26780180	HT29	viability (GeCKOv2 library)	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.860155488318686	[]	[]	3	hSpCas9	negative selection	4018841
38706094	38706117	19	-	26780180	HT29	viability (GeCKOv2 library)	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.660591522269512	[]	[]	2	hSpCas9	negative selection	4018842
38701000	38701023	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	-0.630344564338318	[2]	[0,0]	-9	hSpCas9	positive selection	4187988
38700671	38700694	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.11638578599962515	[3]	[2,3]	3	hSpCas9	positive selection	4187999
38701081	38701104	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	0.1455966563690434	[3]	[2,3]	4	hSpCas9	positive selection	4188009
38701000	38701023	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGGAGCGGTTACCTAAGCCGG	ACTN4	ENSG00000130402	0.0878275770565301	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4252010
38700671	38700694	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	1.2381615277816276	[2]	[5,3,4,1]	8	hSpCas9	positive selection	4252021
38701081	38701104	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCAGCAAAGGCGTCAAGCTGG	ACTN4	ENSG00000130402	1.297362945250777	[2]	[4,0,1,4]	9	hSpCas9	positive selection	4252031
38700671	38700694	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.4092986743405143	[4]	[4,3]	8	hSpCas9	positive selection	4254347
38700601	38700624	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.15060889181116674	[2]	[1,2]	3	hSpCas9	positive selection	4254348
38706094	38706117	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.47119173771669287	[1]	[1,0]	8	hSpCas9	positive selection	4254349
38701051	38701074	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.5601003158599797	[2]	[0,0]	-8	hSpCas9	positive selection	4318630
38701019	38701042	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.5010509832875956	[4]	[4,4]	9	hSpCas9	positive selection	4318631
38704983	38705006	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.15925614634381563	[3]	[4,2]	3	hSpCas9	positive selection	4318632
38706092	38706114	19	-	27760321	OCIAML3	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.5856863892748887	[83,80]	[59,20]	-5	hSpCas9	negative selection	4375916
38708163	38708185	19	-	27760321	OCIAML3	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.09232197023813807	[587,468]	[308,484]	-1	hSpCas9	negative selection	4375917
38709401	38709423	19	-	27760321	OCIAML3	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.6937194993676723	[683,604]	[723,930]	7	hSpCas9	negative selection	4375918
38710268	38710290	19	+	27760321	OCIAML3	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	0.18364429927620013	[389,319]	[305,323]	2	hSpCas9	negative selection	4375919
38714468	38714490	19	+	27760321	OCIAML3	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	0.6207652760640281	[667,586]	[743,764]	7	hSpCas9	negative selection	4375920
38706092	38706114	19	-	27760321	OCIAML2	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.2625527127837217	[83,80]	[31,86]	-3	hSpCas9	negative selection	4459379
38708163	38708185	19	-	27760321	OCIAML2	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.33816545241417384	[587,468]	[308,371]	-4	hSpCas9	negative selection	4459380
38709401	38709423	19	-	27760321	OCIAML2	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.46248708992340615	[683,604]	[610,856]	6	hSpCas9	negative selection	4459381
38710268	38710290	19	+	27760321	OCIAML2	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.6376156596672478	[389,319]	[184,181]	-6	hSpCas9	negative selection	4459382
38714468	38714490	19	+	27760321	OCIAML2	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	0.14046382148321257	[667,586]	[415,745]	1	hSpCas9	negative selection	4459383
38706092	38706114	19	-	27760321	MV411	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.004799940791992974	[83,80]	[3,129]	0	hSpCas9	negative selection	4542842
38708163	38708185	19	-	27760321	MV411	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.22493079673101926	[587,468]	[93,600]	-2	hSpCas9	negative selection	4542843
38709401	38709423	19	-	27760321	MV411	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.2945737052643237	[683,604]	[443,635]	2	hSpCas9	negative selection	4542844
38710268	38710290	19	+	27760321	MV411	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-1.1187977779127394	[389,319]	[52,188]	-6	hSpCas9	negative selection	4542845
38714468	38714490	19	+	27760321	MV411	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.38904333465919533	[667,586]	[285,359]	-3	hSpCas9	negative selection	4542846
38706092	38706114	19	-	27760321	HL60	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	0.6811967981054117	[83,80]	[66,151]	7	hSpCas9	negative selection	4626305
38708163	38708185	19	-	27760321	HL60	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.3844330371784892	[587,468]	[237,424]	-4	hSpCas9	negative selection	4626306
38709401	38709423	19	-	27760321	HL60	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.3143238938784697	[683,604]	[586,723]	4	hSpCas9	negative selection	4626307
38710268	38710290	19	+	27760321	HL60	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.628472983250234	[389,319]	[142,232]	-6	hSpCas9	negative selection	4626308
38714468	38714490	19	+	27760321	HL60	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.3756461249956603	[667,586]	[320,471]	-4	hSpCas9	negative selection	4626309
38706092	38706114	19	-	27760321	HT1080	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	0.6675955409649377	[80,62]	[14,78]	3	hSpCas9	negative selection	4709768
38708163	38708185	19	-	27760321	HT1080	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	2.641353447009255	[468,365]	[988,1090]	9	hSpCas9	negative selection	4709769
38709401	38709423	19	-	27760321	HT1080	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	2.4576076666098245	[604,471]	[1090,1273]	9	hSpCas9	negative selection	4709770
38710268	38710290	19	+	27760321	HT1080	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	1.4971758130613986	[319,249]	[341,296]	7	hSpCas9	negative selection	4709771
38714468	38714490	19	+	27760321	HT1080	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	2.2689020140074048	[586,457]	[679,1356]	9	hSpCas9	negative selection	4709772
38706092	38706114	19	-	27760321	HT29	viability after 7 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.7413841567112862	[80,62]	[36,26,97]	-8	hSpCas9	negative selection	4793231
38708163	38708185	19	-	27760321	HT29	viability after 7 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.02744622860622098	[468,365]	[690,490,423]	0	hSpCas9	negative selection	4793232
38709401	38709423	19	-	27760321	HT29	viability after 7 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.40412460642964965	[604,471]	[1027,751,980]	6	hSpCas9	negative selection	4793233
38710268	38710290	19	+	27760321	HT29	viability after 7 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	0.29890949959851054	[319,249]	[379,488,471]	4	hSpCas9	negative selection	4793234
38714468	38714490	19	+	27760321	HT29	viability after 7 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.1372642731773615	[586,457]	[684,542,613]	-2	hSpCas9	negative selection	4793235
38706092	38706114	19	-	27760321	HT29	viability after 25 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-1.7620925099697842	[80,62]	[37,16,15]	-7	hSpCas9	negative selection	4876694
38708163	38708185	19	-	27760321	HT29	viability after 25 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.37178585566933453	[468,365]	[318,444,341]	-4	hSpCas9	negative selection	4876695
38709401	38709423	19	-	27760321	HT29	viability after 25 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	-0.1527683654532629	[604,471]	[620,468,566]	-1	hSpCas9	negative selection	4876696
38710268	38710290	19	+	27760321	HT29	viability after 25 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.9140507945891757	[319,249]	[152,189,176]	-6	hSpCas9	negative selection	4876697
38714468	38714490	19	+	27760321	HT29	viability after 25 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.30127650705405995	[586,457]	[320,668,471]	-3	hSpCas9	negative selection	4876698
38706092	38706114	19	-	27760321	HT29	viability after 22 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.7667069128630728	[80,62]	[6,77,62]	-6	hSpCas9	negative selection	4960157
38708163	38708185	19	-	27760321	HT29	viability after 22 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.11328367981522922	[468,365]	[392,606,338]	-1	hSpCas9	negative selection	4960158
38709401	38709423	19	-	27760321	HT29	viability after 22 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	-0.4466412511480068	[604,471]	[574,554,234]	-4	hSpCas9	negative selection	4960159
38710268	38710290	19	+	27760321	HT29	viability after 22 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.19106547864839163	[319,249]	[406,235,218]	-2	hSpCas9	negative selection	4960160
38714468	38714490	19	+	27760321	HT29	viability after 22 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.45998782492885676	[586,457]	[513,395,404]	-4	hSpCas9	negative selection	4960161
38706092	38706114	19	-	27760321	HT29	viability after 19 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	0.2655299719056514	[80,62]	[91,182,23]	2	hSpCas9	negative selection	5043620
38708163	38708185	19	-	27760321	HT29	viability after 19 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.19455427949713633	[468,365]	[800,297,200]	-2	hSpCas9	negative selection	5043621
38709401	38709423	19	-	27760321	HT29	viability after 19 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	-0.16824153919169987	[604,471]	[609,885,168]	-1	hSpCas9	negative selection	5043622
38710268	38710290	19	+	27760321	HT29	viability after 19 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.7573371390413682	[319,249]	[208,202,168]	-6	hSpCas9	negative selection	5043623
38714468	38714490	19	+	27760321	HT29	viability after 19 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.38534937433908445	[586,457]	[576,519,293]	-4	hSpCas9	negative selection	5043624
38706092	38706114	19	-	27760321	HT29	viability after 16 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-1.2651302889926148	[80,62]	[45,21,33]	-7	hSpCas9	negative selection	5127083
38708163	38708185	19	-	27760321	HT29	viability after 16 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	0.06817352692668172	[468,365]	[652,391,441]	0	hSpCas9	negative selection	5127084
38709401	38709423	19	-	27760321	HT29	viability after 16 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	-0.254470082156609	[604,471]	[658,335,538]	-3	hSpCas9	negative selection	5127085
38710268	38710290	19	+	27760321	HT29	viability after 16 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	0.1474537869116921	[319,249]	[462,425,178]	1	hSpCas9	negative selection	5127086
38714468	38714490	19	+	27760321	HT29	viability after 16 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	0.05971726229381302	[586,457]	[848,622,377]	0	hSpCas9	negative selection	5127087
38706092	38706114	19	-	27760321	HT29	viability after 13 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-0.1430905151670725	[80,62]	[7,108,107]	-2	hSpCas9	negative selection	5210546
38708163	38708185	19	-	27760321	HT29	viability after 13 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.1906884240412301	[468,365]	[551,385,339]	-2	hSpCas9	negative selection	5210547
38709401	38709423	19	-	27760321	HT29	viability after 13 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	-0.01960474469032225	[604,471]	[749,628,477]	0	hSpCas9	negative selection	5210548
38710268	38710290	19	+	27760321	HT29	viability after 13 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	0.22850098122975526	[319,249]	[543,370,254]	3	hSpCas9	negative selection	5210549
38714468	38714490	19	+	27760321	HT29	viability after 13 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	-0.05419045061332095	[586,457]	[669,546,536]	0	hSpCas9	negative selection	5210550
38706092	38706114	19	-	27760321	HT29	viability after 10 days	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	-2.3419154077090414	[80,62]	[46,0,4]	-9	hSpCas9	negative selection	5294009
38708163	38708185	19	-	27760321	HT29	viability after 10 days	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.15508294387517316	[468,365]	[595,403,403]	-2	hSpCas9	negative selection	5294010
38709401	38709423	19	-	27760321	HT29	viability after 10 days	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	0.26540472760135103	[604,471]	[736,754,927]	3	hSpCas9	negative selection	5294011
38710268	38710290	19	+	27760321	HT29	viability after 10 days	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	0.6849785738854848	[319,249]	[435,467,803]	8	hSpCas9	negative selection	5294012
38714468	38714490	19	+	27760321	HT29	viability after 10 days	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	0.08346424892849191	[586,457]	[666,891,523]	1	hSpCas9	negative selection	5294013
38706092	38706114	19	-	27760321	MOLM13	viability	ACATTGACGTTCTTATACGGGG	ACTN4	ENSG00000130402	1.242739546082891	[83,80]	[219,16]	8	hSpCas9	negative selection	5377472
38708163	38708185	19	-	27760321	MOLM13	viability	TGTCATACTCAATCAGCTCTGG	ACTN4	ENSG00000130402	-0.1298640551268831	[587,468]	[184,343]	-1	hSpCas9	negative selection	5377473
38709401	38709423	19	-	27760321	MOLM13	viability	CATTGTTCAGGTTGGTGACAGG	ACTN4	ENSG00000130402	1.3221570786322925	[683,604]	[589,1177]	8	hSpCas9	negative selection	5377474
38710268	38710290	19	+	27760321	MOLM13	viability	ACGGCCCGGCCCGACGAGAAGG	ACTN4	ENSG00000130402	-0.6182449611349765	[389,319]	[151,110]	-4	hSpCas9	negative selection	5377475
38714468	38714490	19	+	27760321	MOLM13	viability	GGCTGAAACTGCCGCCAACCGG	ACTN4	ENSG00000130402	0.3089602684784032	[667,586]	[582,313]	2	hSpCas9	negative selection	5377476
38647642	38647665	19	+	27661255	K562	viability	GCGGGCTGAAGCAGCTGAAGCGG	ACTN4	ENSG00000130402	0.036590745197763785	[938,946]	[900,662]	1	dCas9-KRAB	negative selection	5460754
38647697	38647720	19	+	27661255	K562	viability	GAGCTGAGGCGGGAGCGGACAGG	ACTN4	ENSG00000130402	0.33751128630412763	[1149,1108]	[1163,1120]	9	dCas9-KRAB	negative selection	5460755
38648014	38648037	19	+	27661255	K562	viability	GGGTCCCGAGAAGGAATTGGCGG	ACTN4	ENSG00000130402	-0.009823619692955643	[588,667]	[537,462]	0	dCas9-KRAB	negative selection	5460756
38648026	38648049	19	+	27661255	K562	viability	GGAATTGGCGGGTCCGGGAAGGG	ACTN4	ENSG00000130402	0.39704056236165863	[1439,1553]	[1822,1358]	9	dCas9-KRAB	negative selection	5460757
38648042	38648065	19	+	27661255	K562	viability	GGAAGGGAATTGGAGTCCTGAGG	ACTN4	ENSG00000130402	-0.059245868268743895	[1393,1258]	[1081,964]	-2	dCas9-KRAB	negative selection	5460758
38648066	38648089	19	+	27661255	K562	viability	GGAATCGCCGAGCTAGAGGAAGG	ACTN4	ENSG00000130402	-0.03460013151808494	[1295,1420]	[1088,1030]	-1	dCas9-KRAB	negative selection	5460759
38700671	38700694	19	-	27260156	BXPC3	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.26577124004951314	[1095]	[1293,1409,1404,1402]	6	hSpCas9	negative selection	5526807
38700601	38700624	19	-	27260156	BXPC3	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.2521183777405881	[264]	[448,256,327,266]	5	hSpCas9	negative selection	5526808
38706094	38706117	19	-	27260156	BXPC3	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.7090005435143638	[71]	[191,90,110,86]	9	hSpCas9	negative selection	5526809
38701051	38701074	19	+	27260156	BXPC3	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.3568175987358416	[256]	[251,171,203,206]	-7	hSpCas9	negative selection	5591090
38701019	38701042	19	-	27260156	BXPC3	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.33080047715920147	[1025]	[1187,1189,1467,1601]	7	hSpCas9	negative selection	5591091
38704983	38705006	19	+	27260156	BXPC3	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.17073814843081092	[900]	[1149,797,1127,1179]	4	hSpCas9	negative selection	5591092
38700671	38700694	19	-	27260156	A673	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.10345162569982747	[1095]	[1254,1240,1073,1337]	-3	hSpCas9	negative selection	5648058
38700601	38700624	19	-	27260156	A673	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.07860436571086116	[264]	[397,286,242,287]	-2	hSpCas9	negative selection	5648059
38706094	38706117	19	-	27260156	A673	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.3357558812308552	[71]	[136,84,138,76]	7	hSpCas9	negative selection	5648060
38701051	38701074	19	+	27260156	A673	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.721805592097773	[256]	[225,117,164,248]	-9	hSpCas9	negative selection	5712341
38701019	38701042	19	-	27260156	A673	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.08844900751033058	[1025]	[1212,1124,1138,1162]	-2	hSpCas9	negative selection	5712342
38704983	38705006	19	+	27260156	A673	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.06540818532212034	[900]	[1280,1013,1020,1236]	1	hSpCas9	negative selection	5712343
38700671	38700694	19	-	27260156	A375	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.1838687653657236	[1095]	[936,1448,1257,926]	-3	hSpCas9	negative selection	5769309
38700601	38700624	19	-	27260156	A375	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.8180235413997271	[264]	[189,139,128,230]	-8	hSpCas9	negative selection	5769310
38706094	38706117	19	-	27260156	A375	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.690333947801276	[71]	[80,113,190,150]	8	hSpCas9	negative selection	5769311
38701051	38701074	19	+	27260156	A375	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.40514549676244427	[256]	[223,380,203,129]	-5	hSpCas9	negative selection	5833592
38701019	38701042	19	-	27260156	A375	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.11647999516874608	[1025]	[1193,1553,1168,1307]	1	hSpCas9	negative selection	5833593
38704983	38705006	19	+	27260156	A375	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.1459875949252728	[900]	[1131,1425,908,1215]	2	hSpCas9	negative selection	5833594
38700671	38700694	19	-	27260156	COLO741	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.05829890761526513	[1095]	[1688,1407,1304]	1	hSpCas9	negative selection	5890560
38700601	38700624	19	-	27260156	COLO741	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.2641437500194721	[264]	[394,304,509]	5	hSpCas9	negative selection	5890561
38706094	38706117	19	-	27260156	COLO741	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.8034799981496663	[71]	[90,243,141]	9	hSpCas9	negative selection	5890562
38701051	38701074	19	+	27260156	COLO741	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.35400223041376877	[256]	[391,224,170]	-6	hSpCas9	negative selection	5954843
38701019	38701042	19	-	27260156	COLO741	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.20205713639717704	[1025]	[1701,1358,1477]	4	hSpCas9	negative selection	5954844
38704983	38705006	19	+	27260156	COLO741	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.10536385386064107	[900]	[1381,1181,1165]	2	hSpCas9	negative selection	5954845
38700671	38700694	19	-	27260156	CAL120	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.003997584841393564	[1095]	[1666,1091,1387]	0	hSpCas9	negative selection	6011811
38700601	38700624	19	-	27260156	CAL120	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	1.2725280296103163	[264]	[1413,745,330]	9	hSpCas9	negative selection	6011812
38706094	38706117	19	-	27260156	CAL120	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.1482343729973505	[71]	[254,141,206]	9	hSpCas9	negative selection	6011813
38701051	38701074	19	+	27260156	CAL120	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.13250460258774355	[256]	[469,255,177]	-2	hSpCas9	negative selection	6076094
38701019	38701042	19	-	27260156	CAL120	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.006391451621543975	[1025]	[1406,1310,1117]	0	hSpCas9	negative selection	6076095
38704983	38705006	19	+	27260156	CAL120	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.13853592359407407	[900]	[1619,1066,1075]	2	hSpCas9	negative selection	6076096
38700671	38700694	19	-	27260156	CADOES1	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.22281832772120835	[1095]	[741,985,699,1073]	-4	hSpCas9	negative selection	6133062
38700601	38700624	19	-	27260156	CADOES1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.10989755745155605	[264]	[273,253,169,214]	-2	hSpCas9	negative selection	6133063
38706094	38706117	19	-	27260156	CADOES1	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.8054207636388715	[71]	[76,97,154,138]	9	hSpCas9	negative selection	6133064
38701051	38701074	19	+	27260156	CADOES1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.6131373189115331	[256]	[126,147,145,205]	-8	hSpCas9	negative selection	6197345
38701019	38701042	19	-	27260156	CADOES1	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.09442616689618588	[1025]	[903,1092,1048,1029]	1	hSpCas9	negative selection	6197346
38704983	38705006	19	+	27260156	CADOES1	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.15999582089518072	[900]	[910,1019,783,1033]	2	hSpCas9	negative selection	6197347
38700671	38700694	19	-	27260156	EWS502	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.07209289815357556	[1095]	[1194,1116,1188,1394]	1	hSpCas9	negative selection	6254313
38700601	38700624	19	-	27260156	EWS502	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.21254678789080006	[264]	[183,373,341,421]	4	hSpCas9	negative selection	6254314
38706094	38706117	19	-	27260156	EWS502	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.2695010221433014	[71]	[275,70,201,178]	9	hSpCas9	negative selection	6254315
38701051	38701074	19	+	27260156	EWS502	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.12805828573283284	[256]	[233,343,183,228]	-2	hSpCas9	negative selection	6318596
38701019	38701042	19	-	27260156	EWS502	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.38059154254129424	[1025]	[1438,1096,1520,1622]	6	hSpCas9	negative selection	6318597
38704983	38705006	19	+	27260156	EWS502	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.1827571972438785	[900]	[1186,963,1036,1135]	3	hSpCas9	negative selection	6318598
38700671	38700694	19	-	27260156	EW8	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.196990714044448	[1095]	[892,931,664,639]	-4	hSpCas9	negative selection	6375564
38700601	38700624	19	-	27260156	EW8	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.21863389314304904	[264]	[192,130,179,234]	-4	hSpCas9	negative selection	6375565
38706094	38706117	19	-	27260156	EW8	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.0177569543728	[71]	[122,99,73,182]	9	hSpCas9	negative selection	6375566
38701051	38701074	19	+	27260156	EW8	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.9925284354500895	[256]	[120,121,112,62]	-9	hSpCas9	negative selection	6439847
38701019	38701042	19	-	27260156	EW8	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.07406874876322567	[1025]	[1049,698,770,668]	-1	hSpCas9	negative selection	6439848
38704983	38705006	19	+	27260156	EW8	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	-0.0007474842666488346	[900]	[553,745,803,780]	0	hSpCas9	negative selection	6439849
38700671	38700694	19	-	27260156	CORL105	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.14469525794520988	[1095]	[1231,1023,1360,1061]	-3	hSpCas9	negative selection	6496815
38700601	38700624	19	-	27260156	CORL105	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.02400011981454553	[264]	[297,315,286,315]	0	hSpCas9	negative selection	6496816
38706094	38706117	19	-	27260156	CORL105	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.6887767883770932	[71]	[157,102,230,67]	9	hSpCas9	negative selection	6496817
38701051	38701074	19	+	27260156	CORL105	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.10797710944862882	[256]	[232,264,309,483]	2	hSpCas9	negative selection	6561098
38701019	38701042	19	-	27260156	CORL105	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.08567857478119723	[1025]	[1164,1192,1216,965]	-1	hSpCas9	negative selection	6561099
38704983	38705006	19	+	27260156	CORL105	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.0795084459215879	[900]	[1141,1082,1199,1047]	1	hSpCas9	negative selection	6561100
38700671	38700694	19	-	27260156	HS294T	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.11981611299347361	[1095]	[337,431,463,650]	1	hSpCas9	negative selection	6618066
38700601	38700624	19	-	27260156	HS294T	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.005644329298723827	[264]	[90,139,82,91]	0	hSpCas9	negative selection	6618067
38706094	38706117	19	-	27260156	HS294T	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.163386061303152	[71]	[108,40,39,53]	9	hSpCas9	negative selection	6618068
38701051	38701074	19	+	27260156	HS294T	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.17920723647574366	[256]	[37,91,124,102]	-3	hSpCas9	negative selection	6682349
38701019	38701042	19	-	27260156	HS294T	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.1020878043960114	[1025]	[319,361,391,415]	-1	hSpCas9	negative selection	6682350
38704983	38705006	19	+	27260156	HS294T	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.052426790141537616	[900]	[352,402,316,371]	0	hSpCas9	negative selection	6682351
38700671	38700694	19	-	27260156	HCC44	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.1272429260536776	[1095]	[1839,1159,1464,1040]	2	hSpCas9	negative selection	6739317
38700601	38700624	19	-	27260156	HCC44	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.27893564281118377	[264]	[382,276,402,407]	4	hSpCas9	negative selection	6739318
38706094	38706117	19	-	27260156	HCC44	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.9965342663733128	[71]	[166,125,312,76]	9	hSpCas9	negative selection	6739319
38701051	38701074	19	+	27260156	HCC44	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.1636075132573992	[256]	[334,184,309,232]	-3	hSpCas9	negative selection	6803600
38701019	38701042	19	-	27260156	HCC44	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.34843747607251996	[1025]	[1518,1128,2005,1390]	5	hSpCas9	negative selection	6803601
38704983	38705006	19	+	27260156	HCC44	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.5266041463243271	[900]	[2032,819,1779,1425]	8	hSpCas9	negative selection	6803602
38700671	38700694	19	-	27260156	G402	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.6841802551466568	[1095]	[888,718,789,924]	-7	hSpCas9	negative selection	6860568
38700601	38700624	19	-	27260156	G402	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.09323202532270936	[264]	[725,206,98,237]	-1	hSpCas9	negative selection	6860569
38706094	38706117	19	-	27260156	G402	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.061475475855174	[71]	[211,154,349,25]	9	hSpCas9	negative selection	6860570
38701051	38701074	19	+	27260156	G402	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-1.5866403618764013	[256]	[92,138,110,75]	-9	hSpCas9	negative selection	6924851
38701019	38701042	19	-	27260156	G402	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.5487356680157821	[1025]	[1364,678,640,800]	-6	hSpCas9	negative selection	6924852
38704983	38705006	19	+	27260156	G402	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	-0.2806140626819237	[900]	[964,1226,734,725]	-4	hSpCas9	negative selection	6924853
38700671	38700694	19	-	27260156	L33	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.466374390133925	[1095]	[1573,684,828,1489]	8	hSpCas9	negative selection	6981819
38700601	38700624	19	-	27260156	L33	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.17470071968363543	[264]	[234,143,170,338]	4	hSpCas9	negative selection	6981820
38706094	38706117	19	-	27260156	L33	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.4753847513149658	[71]	[103,26,53,143]	8	hSpCas9	negative selection	6981821
38701051	38701074	19	+	27260156	L33	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.12479899972989483	[256]	[207,140,181,280]	2	hSpCas9	negative selection	7046102
38701019	38701042	19	-	27260156	L33	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.3675545568441754	[1025]	[1336,545,777,1385]	7	hSpCas9	negative selection	7046103
38704983	38705006	19	+	27260156	L33	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.040219072708638115	[900]	[686,489,546,957]	0	hSpCas9	negative selection	7046104
38700671	38700694	19	-	27260156	K562	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.23911625222962318	[1095]	[596,1104,659,915]	-3	hSpCas9	negative selection	7103070
38700601	38700624	19	-	27260156	K562	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.44909922217273934	[264]	[378,54,110,155]	-5	hSpCas9	negative selection	7103071
38706094	38706117	19	-	27260156	K562	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.9461629940265714	[71]	[58,69,298,62]	9	hSpCas9	negative selection	7103072
38701051	38701074	19	+	27260156	K562	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.46838025019836704	[256]	[273,127,167,102]	-5	hSpCas9	negative selection	7167353
38701019	38701042	19	-	27260156	K562	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.048838077735654295	[1025]	[776,609,1383,739]	0	hSpCas9	negative selection	7167354
38704983	38705006	19	+	27260156	K562	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.3016808570778492	[900]	[1365,1139,681,809]	4	hSpCas9	negative selection	7167355
38700671	38700694	19	-	27260156	HT29	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.1175547801670127	[1095]	[1271,1527,1708,1276]	2	hSpCas9	negative selection	7224321
38700601	38700624	19	-	27260156	HT29	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.22259267990738651	[264]	[303,359,463,366]	4	hSpCas9	negative selection	7224322
38706094	38706117	19	-	27260156	HT29	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.41345257829258397	[71]	[78,174,91,120]	7	hSpCas9	negative selection	7224323
38701051	38701074	19	+	27260156	HT29	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.6608981459306135	[256]	[331,179,197,99]	-8	hSpCas9	negative selection	7288604
38701019	38701042	19	-	27260156	HT29	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.26557132067833455	[1025]	[1765,1532,1196,1511]	5	hSpCas9	negative selection	7288605
38704983	38705006	19	+	27260156	HT29	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.25106423522371946	[900]	[1375,1314,1378,1158]	5	hSpCas9	negative selection	7288606
38700671	38700694	19	-	27260156	MHHES1	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.16866581042988682	[1095]	[1896,1260,1226,1219]	3	hSpCas9	negative selection	7345572
38700601	38700624	19	-	27260156	MHHES1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.1683788730735737	[264]	[311,318,222,222]	-3	hSpCas9	negative selection	7345573
38706094	38706117	19	-	27260156	MHHES1	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.6115578212558539	[71]	[66,218,149,71]	9	hSpCas9	negative selection	7345574
38701051	38701074	19	+	27260156	MHHES1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.055472910170659695	[256]	[319,300,252,247]	-1	hSpCas9	negative selection	7409855
38701019	38701042	19	-	27260156	MHHES1	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.2446234066360189	[1025]	[1310,1512,1469,1198]	4	hSpCas9	negative selection	7409856
38704983	38705006	19	+	27260156	MHHES1	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.3122129852300898	[900]	[1575,1051,1251,1168]	5	hSpCas9	negative selection	7409857
38700671	38700694	19	-	27260156	MEWO	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.07903666155409206	[1095]	[1097,884,953]	-2	hSpCas9	negative selection	7466823
38700601	38700624	19	-	27260156	MEWO	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.3108471422809528	[264]	[336,356,233]	6	hSpCas9	negative selection	7466824
38706094	38706117	19	-	27260156	MEWO	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.23651051274845925	[71]	[155,60,35]	5	hSpCas9	negative selection	7466825
38701051	38701074	19	+	27260156	MEWO	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.5150205166079181	[256]	[204,136,169]	-8	hSpCas9	negative selection	7531106
38701019	38701042	19	-	27260156	MEWO	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.1281301655072271	[1025]	[1064,1247,835]	3	hSpCas9	negative selection	7531107
38704983	38705006	19	+	27260156	MEWO	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.07465762745907989	[900]	[999,823,860]	1	hSpCas9	negative selection	7531108
38700671	38700694	19	-	27260156	LNCAPCLONEFGC	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.33115860037078004	[1095]	[665,903,842,745]	-5	hSpCas9	negative selection	7588074
38700601	38700624	19	-	27260156	LNCAPCLONEFGC	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.6511593484633641	[264]	[160,142,207,107]	-7	hSpCas9	negative selection	7588075
38706094	38706117	19	-	27260156	LNCAPCLONEFGC	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.1374946814873068	[71]	[179,131,96,157]	9	hSpCas9	negative selection	7588076
38701051	38701074	19	+	27260156	LNCAPCLONEFGC	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.3818986558011662	[256]	[167,65,136,344]	-5	hSpCas9	negative selection	7652357
38701019	38701042	19	-	27260156	LNCAPCLONEFGC	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.19110779135009393	[1025]	[614,836,987,843]	-3	hSpCas9	negative selection	7652358
38704983	38705006	19	+	27260156	LNCAPCLONEFGC	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.19541185519255266	[900]	[903,1047,821,939]	3	hSpCas9	negative selection	7652359
38700671	38700694	19	-	27260156	PANC0327	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.6394733909635193	[1095]	[1512,1235,1638,1713]	8	hSpCas9	negative selection	7709325
38700601	38700624	19	-	27260156	PANC0327	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.6576651173381323	[264]	[183,540,350,371]	8	hSpCas9	negative selection	7709326
38706094	38706117	19	-	27260156	PANC0327	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.488650594844402	[71]	[71,47,160,81]	7	hSpCas9	negative selection	7709327
38701051	38701074	19	+	27260156	PANC0327	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.03830917948838952	[256]	[381,218,295,54]	0	hSpCas9	negative selection	7773608
38701019	38701042	19	-	27260156	PANC0327	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.463195354691037	[1025]	[1362,1048,1736,912]	6	hSpCas9	negative selection	7773609
38704983	38705006	19	+	27260156	PANC0327	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.6751038243530093	[900]	[1638,1270,793,1436]	8	hSpCas9	negative selection	7773610
38700671	38700694	19	-	27260156	NCIH2009	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.22925953314662206	[1095]	[1922,1646,1839]	3	hSpCas9	negative selection	7830576
38700601	38700624	19	-	27260156	NCIH2009	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.035499038067660194	[264]	[358,363,410]	0	hSpCas9	negative selection	7830577
38706094	38706117	19	-	27260156	NCIH2009	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.23035308051516568	[71]	[106,98,145]	3	hSpCas9	negative selection	7830578
38701051	38701074	19	+	27260156	NCIH2009	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.1487979768660126	[256]	[516,401,297]	2	hSpCas9	negative selection	7894859
38701019	38701042	19	-	27260156	NCIH2009	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.0973003380425268	[1025]	[1710,1586,1333]	1	hSpCas9	negative selection	7894860
38704983	38705006	19	+	27260156	NCIH2009	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.4619807756267288	[900]	[2066,1390,1812]	6	hSpCas9	negative selection	7894861
38700671	38700694	19	-	27260156	NCIH1373	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.14379514102346658	[1095]	[1147,1126,867,346]	-1	hSpCas9	negative selection	7951827
38700601	38700624	19	-	27260156	NCIH1373	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-1.0432452504246865	[264]	[173,188,79,34]	-8	hSpCas9	negative selection	7951828
38706094	38706117	19	-	27260156	NCIH1373	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	1.173094368563789	[71]	[425,91,128,32]	9	hSpCas9	negative selection	7951829
38701051	38701074	19	+	27260156	NCIH1373	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.4560104383475646	[256]	[365,164,181,39]	-4	hSpCas9	negative selection	8016110
38701019	38701042	19	-	27260156	NCIH1373	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.3174698401370466	[1025]	[1121,1050,1948,418]	3	hSpCas9	negative selection	8016111
38704983	38705006	19	+	27260156	NCIH1373	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.5302937961790647	[900]	[1287,1302,1792,373]	5	hSpCas9	negative selection	8016112
38700671	38700694	19	-	27260156	PATU8902	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.6380019365498119	[1095]	[863,1475,536,1180]	-6	hSpCas9	negative selection	8073078
38700601	38700624	19	-	27260156	PATU8902	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.007756985074698353	[264]	[419,310,214,583]	0	hSpCas9	negative selection	8073079
38706094	38706117	19	-	27260156	PATU8902	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.5440258261841486	[71]	[69,235,106,186]	5	hSpCas9	negative selection	8073080
38701051	38701074	19	+	27260156	PATU8902	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.2911823260784753	[256]	[254,396,387,77]	-3	hSpCas9	negative selection	8137361
38701019	38701042	19	-	27260156	PATU8902	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.3796111561359746	[1025]	[1385,897,676,1586]	-4	hSpCas9	negative selection	8137362
38704983	38705006	19	+	27260156	PATU8902	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.42501791618241114	[900]	[1870,1541,1378,2053]	4	hSpCas9	negative selection	8137363
38700671	38700694	19	-	27260156	PANC1	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.8058144155459845	[1095]	[509,622,467,557]	-8	hSpCas9	negative selection	8194329
38700601	38700624	19	-	27260156	PANC1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-1.7854883204388967	[264]	[47,53,78,77]	-9	hSpCas9	negative selection	8194330
38706094	38706117	19	-	27260156	PANC1	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	-0.04026246019235469	[71]	[46,48,56,80]	0	hSpCas9	negative selection	8194331
38701051	38701074	19	+	27260156	PANC1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-1.1015399251223128	[256]	[60,87,102,147]	-8	hSpCas9	negative selection	8258612
38701019	38701042	19	-	27260156	PANC1	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-1.0735322373375609	[1025]	[479,474,401,334]	-8	hSpCas9	negative selection	8258613
38704983	38705006	19	+	27260156	PANC1	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	-0.08219369213330219	[900]	[617,892,709,726]	-1	hSpCas9	negative selection	8258614
38700671	38700694	19	-	27260156	PANC0813	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.5832335227040688	[1095]	[1691,2352,2181,1488]	8	hSpCas9	negative selection	8315580
38700601	38700624	19	-	27260156	PANC0813	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.6919264082554455	[264]	[451,413,438,689]	9	hSpCas9	negative selection	8315581
38706094	38706117	19	-	27260156	PANC0813	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.9687869488208087	[71]	[102,208,176,166]	9	hSpCas9	negative selection	8315582
38701051	38701074	19	+	27260156	PANC0813	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.5350482466461467	[256]	[255,151,177,248]	-7	hSpCas9	negative selection	8379863
38701019	38701042	19	-	27260156	PANC0813	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.1923537769697523	[1025]	[1473,1410,1400,1236]	3	hSpCas9	negative selection	8379864
38704983	38705006	19	+	27260156	PANC0813	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.36815509016793546	[900]	[1765,1309,1358,1079]	6	hSpCas9	negative selection	8379865
38700671	38700694	19	-	27260156	RDES	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.0795090567160277	[1095]	[899,1119,1358,1477]	-1	hSpCas9	negative selection	8436831
38700601	38700624	19	-	27260156	RDES	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.0865730728183356	[264]	[286,267,278,308]	-1	hSpCas9	negative selection	8436832
38706094	38706117	19	-	27260156	RDES	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.7955774160683422	[71]	[128,161,137,141]	9	hSpCas9	negative selection	8436833
38701051	38701074	19	+	27260156	RDES	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.23711594352831444	[256]	[227,286,200,282]	-4	hSpCas9	negative selection	8501114
38701019	38701042	19	-	27260156	RDES	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.053164460499099286	[1025]	[1042,1093,1257,1569]	0	hSpCas9	negative selection	8501115
38704983	38705006	19	+	27260156	RDES	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.22303408335875885	[900]	[1073,1257,1168,1339]	3	hSpCas9	negative selection	8501116
38700671	38700694	19	-	27260156	PC3	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.041865496093657306	[1095]	[762,1157,1481,1278]	0	hSpCas9	negative selection	8558082
38700601	38700624	19	-	27260156	PC3	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.036005953382725164	[264]	[229,187,483,195]	-1	hSpCas9	negative selection	8558083
38706094	38706117	19	-	27260156	PC3	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.6431451234660832	[71]	[80,75,246,99]	9	hSpCas9	negative selection	8558084
38701051	38701074	19	+	27260156	PC3	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.33905476965204373	[256]	[114,187,285,277]	-6	hSpCas9	negative selection	8622365
38701019	38701042	19	-	27260156	PC3	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.05223358830021341	[1025]	[633,1171,1520,1178]	1	hSpCas9	negative selection	8622366
38704983	38705006	19	+	27260156	PC3	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.10286769261432471	[900]	[731,955,1515,853]	2	hSpCas9	negative selection	8622367
38700671	38700694	19	-	27260156	PATU8988T	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.6855134499072927	[1095]	[335,962,486,897]	-8	hSpCas9	negative selection	8679333
38700601	38700624	19	-	27260156	PATU8988T	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-1.414890037313909	[264]	[50,131,42,167]	-9	hSpCas9	negative selection	8679334
38706094	38706117	19	-	27260156	PATU8988T	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.7172394836026004	[71]	[100,206,94,58]	9	hSpCas9	negative selection	8679335
38701051	38701074	19	+	27260156	PATU8988T	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-1.1109447425594987	[256]	[122,90,132,109]	-9	hSpCas9	negative selection	8743616
38701019	38701042	19	-	27260156	PATU8988T	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.23270647768715902	[1025]	[769,1178,570,893]	-4	hSpCas9	negative selection	8743617
38704983	38705006	19	+	27260156	PATU8988T	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.2658375047922704	[900]	[978,874,1245,1069]	4	hSpCas9	negative selection	8743618
38700671	38700694	19	-	27260156	T47D	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.16933913229020958	[1095]	[1146,1114,1123,1157]	-4	hSpCas9	negative selection	8800584
38700601	38700624	19	-	27260156	T47D	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.02181000150142931	[264]	[367,256,348,243]	0	hSpCas9	negative selection	8800585
38706094	38706117	19	-	27260156	T47D	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.9043426298302384	[71]	[107,227,168,114]	9	hSpCas9	negative selection	8800586
38701051	38701074	19	+	27260156	T47D	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.5022784841425659	[256]	[205,248,189,196]	-8	hSpCas9	negative selection	8864867
38701019	38701042	19	-	27260156	T47D	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	-0.0228027206404553	[1025]	[1059,1095,1276,1280]	0	hSpCas9	negative selection	8864868
38704983	38705006	19	+	27260156	T47D	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.10479532699044325	[900]	[1177,1038,1192,1110]	2	hSpCas9	negative selection	8864869
38700671	38700694	19	-	27260156	SU8686	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.1860140753322721	[1095]	[1007,1038,1465,1527]	3	hSpCas9	negative selection	8921835
38700601	38700624	19	-	27260156	SU8686	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.38908065596841	[264]	[161,158,231,269]	-6	hSpCas9	negative selection	8921836
38706094	38706117	19	-	27260156	SU8686	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.9417490033237301	[71]	[60,64,246,206]	9	hSpCas9	negative selection	8921837
38701051	38701074	19	+	27260156	SU8686	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.2775859017131076	[256]	[192,161,293,198]	-5	hSpCas9	negative selection	8986118
38701019	38701042	19	-	27260156	SU8686	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.26605299481512024	[1025]	[1024,1061,1414,1470]	4	hSpCas9	negative selection	8986119
38704983	38705006	19	+	27260156	SU8686	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.11243254572651551	[900]	[817,913,1176,977]	2	hSpCas9	negative selection	8986120
38700671	38700694	19	-	27260156	SKES1	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.05009784725892441	[1095]	[950,1318,1084,893]	-1	hSpCas9	negative selection	9043086
38700601	38700624	19	-	27260156	SKES1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.12106473289514874	[264]	[276,324,237,154]	-3	hSpCas9	negative selection	9043087
38706094	38706117	19	-	27260156	SKES1	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.7407096718287749	[71]	[117,152,134,80]	9	hSpCas9	negative selection	9043088
38701051	38701074	19	+	27260156	SKES1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.4852969812582578	[256]	[155,216,205,154]	-8	hSpCas9	negative selection	9107369
38701019	38701042	19	-	27260156	SKES1	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.3504182560833542	[1025]	[1676,1411,1040,1160]	7	hSpCas9	negative selection	9107370
38704983	38705006	19	+	27260156	SKES1	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.126927435383544	[900]	[1028,1034,1064,817]	2	hSpCas9	negative selection	9107371
38700671	38700694	19	-	27260156	TOV112D	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.030452040350323673	[1095]	[1060,918,1064,1208]	0	hSpCas9	negative selection	9164337
38700601	38700624	19	-	27260156	TOV112D	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.6586045206249559	[264]	[401,385,290,581]	9	hSpCas9	negative selection	9164338
38706094	38706117	19	-	27260156	TOV112D	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.4318308527734338	[71]	[73,127,111,80]	7	hSpCas9	negative selection	9164339
38701051	38701074	19	+	27260156	TOV112D	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.6694155792298221	[256]	[139,203,162,148]	-8	hSpCas9	negative selection	9228620
38701019	38701042	19	-	27260156	TOV112D	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.21423275443422773	[1025]	[1136,1231,971,1423]	4	hSpCas9	negative selection	9228621
38704983	38705006	19	+	27260156	TOV112D	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.09560748193458457	[900]	[655,1381,1032,863]	1	hSpCas9	negative selection	9228622
38700671	38700694	19	-	27260156	TC71	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	-0.04046824452859821	[1095]	[1187,1244,987,1152]	-1	hSpCas9	negative selection	9285588
38700601	38700624	19	-	27260156	TC71	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.06359886461526709	[264]	[370,296,274,239]	1	hSpCas9	negative selection	9285589
38706094	38706117	19	-	27260156	TC71	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.446630230807993	[71]	[69,185,90,72]	8	hSpCas9	negative selection	9285590
38701051	38701074	19	+	27260156	TC71	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.9342583196913669	[256]	[152,123,145,153]	-9	hSpCas9	negative selection	9349871
38701019	38701042	19	-	27260156	TC71	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.14524162994843404	[1025]	[1081,1105,1298,1388]	3	hSpCas9	negative selection	9349872
38704983	38705006	19	+	27260156	TC71	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.07226606029480076	[900]	[715,1200,957,1206]	1	hSpCas9	negative selection	9349873
38700671	38700694	19	-	27260156	TC32	viability	GCATGAGCTTGAGCCCGTCTCGG	ACTN4	ENSG00000130402	0.05881760065918451	[1095]	[854,972,1391,1128]	1	hSpCas9	negative selection	9406839
38700601	38700624	19	-	27260156	TC32	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.3644617889138121	[264]	[205,88,262,258]	-6	hSpCas9	negative selection	9406840
38706094	38706117	19	-	27260156	TC32	viability	TGCACATTGACGTTCTTATACGG	ACTN4	ENSG00000130402	0.6800620123268262	[71]	[101,168,70,50]	9	hSpCas9	negative selection	9406841
38701051	38701074	19	+	27260156	TC32	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.9189548450918043	[256]	[162,76,157,124]	-9	hSpCas9	negative selection	9471122
38701019	38701042	19	-	27260156	TC32	viability	ACTCTCATCTTCCCCCGCTCCGG	ACTN4	ENSG00000130402	0.08210127280187285	[1025]	[1010,753,1332,1082]	1	hSpCas9	negative selection	9471123
38704983	38705006	19	+	27260156	TC32	viability	CATCCTTAGGTTCGCCATCCAGG	ACTN4	ENSG00000130402	0.16813428886058868	[900]	[1160,601,1204,927]	3	hSpCas9	negative selection	9471124
38647826	38647849	19	+	27869803	HPAFII	viability after 27 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.2567534496525381	[262]	[166,72,NaN]	-2	hSpCas9	negative selection	9567600
38700658	38700681	19	+	27869803	HPAFII	viability after 27 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.6424311193841552	[550]	[359,528,NaN]	5	hSpCas9	negative selection	9567601
38701005	38701028	19	+	27869803	HPAFII	viability after 27 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.3678754291504678	[188]	[58,91,NaN]	-3	hSpCas9	negative selection	9567602
38704944	38704967	19	+	27869803	HPAFII	viability after 27 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-1.0224524643818091	[404]	[100,107,NaN]	-6	hSpCas9	negative selection	9567603
38706047	38706070	19	-	27869803	HPAFII	viability after 27 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.7772269035988811	[202]	[64,59,NaN]	-5	hSpCas9	negative selection	9567604
38708150	38708173	19	-	27869803	HPAFII	viability after 27 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.13998225424494984	[238]	[210,77,NaN]	1	hSpCas9	negative selection	9567605
38647826	38647849	19	+	27869803	HPAFII	viability after 15 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.1758052186484733	[262]	[330,311,NaN]	2	hSpCas9	negative selection	9650049
38700658	38700681	19	+	27869803	HPAFII	viability after 15 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.04257369621086249	[550]	[731,533,NaN]	0	hSpCas9	negative selection	9650050
38701005	38701028	19	+	27869803	HPAFII	viability after 15 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	0.4793509373908633	[188]	[580,97,NaN]	5	hSpCas9	negative selection	9650051
38704944	38704967	19	+	27869803	HPAFII	viability after 15 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.6736676428591503	[404]	[336,232,NaN]	-6	hSpCas9	negative selection	9650052
38706047	38706070	19	-	27869803	HPAFII	viability after 15 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.09711682432111374	[202]	[360,153,NaN]	1	hSpCas9	negative selection	9650053
38708150	38708173	19	-	27869803	HPAFII	viability after 15 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	0.3759832411349298	[238]	[513,220,NaN]	4	hSpCas9	negative selection	9650054
38647826	38647849	19	+	27869803	ASPC1	viability after 36 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.31655000609263684	[541]	[207,98,152]	-3	hSpCas9	negative selection	9732498
38700658	38700681	19	+	27869803	ASPC1	viability after 36 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	-0.597856377791883	[1131]	[269,298,221]	-5	hSpCas9	negative selection	9732499
38701005	38701028	19	+	27869803	ASPC1	viability after 36 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	0.3266348880047769	[567]	[267,315,178]	3	hSpCas9	negative selection	9732500
38704944	38704967	19	+	27869803	ASPC1	viability after 36 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	0.4274427878042637	[742]	[406,454,219]	4	hSpCas9	negative selection	9732501
38706047	38706070	19	-	27869803	ASPC1	viability after 36 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	0.7917500900646937	[551]	[311,256,405]	7	hSpCas9	negative selection	9732502
38708150	38708173	19	-	27869803	ASPC1	viability after 36 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.1211699652276283	[805]	[141,391,231]	-1	hSpCas9	negative selection	9732503
38647826	38647849	19	+	27869803	PATU8988S	viability after 35 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.9828875984589887	[345]	[238,311,NaN]	8	hSpCas9	negative selection	9814947
38700658	38700681	19	+	27869803	PATU8988S	viability after 35 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.8226349301182633	[966]	[605,771,NaN]	8	hSpCas9	negative selection	9814948
38701005	38701028	19	+	27869803	PATU8988S	viability after 35 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.8599897868256356	[425]	[106,81,NaN]	-7	hSpCas9	negative selection	9814949
38704944	38704967	19	+	27869803	PATU8988S	viability after 35 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.017683829126054984	[700]	[229,327,NaN]	0	hSpCas9	negative selection	9814950
38706047	38706070	19	-	27869803	PATU8988S	viability after 35 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.4965814738242561	[552]	[96,218,NaN]	-5	hSpCas9	negative selection	9814951
38708150	38708173	19	-	27869803	PATU8988S	viability after 35 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.8882358270624808	[714]	[190,119,NaN]	-7	hSpCas9	negative selection	9814952
38647826	38647849	19	+	27869803	PATU8988S	viability after 31 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.9500945854084888	[345]	[211,335,NaN]	9	hSpCas9	negative selection	9897396
38700658	38700681	19	+	27869803	PATU8988S	viability after 31 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.665862748808434	[966]	[499,753,NaN]	7	hSpCas9	negative selection	9897397
38701005	38701028	19	+	27869803	PATU8988S	viability after 31 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-1.0920507034376166	[425]	[91,63,NaN]	-8	hSpCas9	negative selection	9897398
38704944	38704967	19	+	27869803	PATU8988S	viability after 31 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.21899986522423295	[700]	[200,289,NaN]	-2	hSpCas9	negative selection	9897399
38706047	38706070	19	-	27869803	PATU8988S	viability after 31 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.6501373838775847	[552]	[92,200,NaN]	-6	hSpCas9	negative selection	9897400
38708150	38708173	19	-	27869803	PATU8988S	viability after 31 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.7050935343117704	[714]	[184,161,NaN]	-6	hSpCas9	negative selection	9897401
38647826	38647849	19	+	27869803	HPAFII	viability after 35 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	0.15216050237037335	[262]	[170,121,NaN]	0	hSpCas9	negative selection	9979845
38700658	38700681	19	+	27869803	HPAFII	viability after 35 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.9271471122503996	[550]	[290,799,NaN]	6	hSpCas9	negative selection	9979846
38701005	38701028	19	+	27869803	HPAFII	viability after 35 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	-0.885978388202593	[188]	[71,28,NaN]	-5	hSpCas9	negative selection	9979847
38704944	38704967	19	+	27869803	HPAFII	viability after 35 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.9385423518676176	[404]	[58,160,NaN]	-5	hSpCas9	negative selection	9979848
38706047	38706070	19	-	27869803	HPAFII	viability after 35 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-1.2107852792244254	[202]	[18,72,NaN]	-6	hSpCas9	negative selection	9979849
38708150	38708173	19	-	27869803	HPAFII	viability after 35 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.28522298589939415	[238]	[87,111,NaN]	-2	hSpCas9	negative selection	9979850
38647826	38647849	19	+	27869803	HPAFII	viability after 31 days	CATGGGCGACTACATGGCCCAGG	ACTN4	ENSG00000130402	-0.2464566237676116	[262]	[144,101,NaN]	-2	hSpCas9	negative selection	10062294
38700658	38700681	19	+	27869803	HPAFII	viability after 31 days	TTGATGAGGACTTCCGAGACGGG	ACTN4	ENSG00000130402	0.9307058051354076	[550]	[420,772,NaN]	7	hSpCas9	negative selection	10062295
38701005	38701028	19	+	27869803	HPAFII	viability after 31 days	AGCGGTTACCTAAGCCGGAGCGG	ACTN4	ENSG00000130402	0.07811561611142825	[188]	[155,63,NaN]	0	hSpCas9	negative selection	10062296
38704944	38704967	19	+	27869803	HPAFII	viability after 31 days	CGGCAACGCAAAGATGACCCTGG	ACTN4	ENSG00000130402	-0.8458206917634172	[404]	[80,175,NaN]	-5	hSpCas9	negative selection	10062297
38706047	38706070	19	-	27869803	HPAFII	viability after 31 days	AAGGAGCCCTTCCTTGGCCGAGG	ACTN4	ENSG00000130402	-0.6777252488108593	[202]	[64,77,NaN]	-4	hSpCas9	negative selection	10062298
38708150	38708173	19	-	27869803	HPAFII	viability after 31 days	TCAGCTCTGGTCTGTGCCGGTGG	ACTN4	ENSG00000130402	-0.08165367130215015	[238]	[109,144,NaN]	0	hSpCas9	negative selection	10062299
38721554	38721577	19	+	28162770	P31FUJ	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	0.004889353304951882	[66]	[78]	0	hSpCas9	negative selection	10106472
38723701	38723724	19	+	28162770	P31FUJ	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.37917324794449747	[387]	[592]	4	hSpCas9	negative selection	10106473
38647742	38647765	19	+	28162770	P31FUJ	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.36018151089060646	[141]	[129]	-3	hSpCas9	negative selection	10106474
38700601	38700624	19	-	28162770	P31FUJ	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.25943733091784527	[163]	[160]	-2	hSpCas9	negative selection	10106475
38700614	38700637	19	+	28162770	P31FUJ	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.3521602963067776	[251]	[377]	4	hSpCas9	negative selection	10106476
38701051	38701074	19	+	28162770	P31FUJ	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.10898631283382676	[100]	[127]	1	hSpCas9	negative selection	10106477
38714516	38714539	19	+	28162770	P31FUJ	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	-0.12427774763620969	[127]	[137]	-1	hSpCas9	negative selection	10106478
38717112	38717135	19	-	28162770	P31FUJ	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.3463647632375785	[250]	[231]	-3	hSpCas9	negative selection	10106479
38717151	38717174	19	+	28162770	P31FUJ	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-4.787391056092016	[93]	[3]	-9	hSpCas9	negative selection	10106480
38723683	38723706	19	-	28162770	P31FUJ	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.058472023852065215	[217]	[245]	0	hSpCas9	negative selection	10106481
38721554	38721577	19	+	28162770	TF1	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10275838
38723701	38723724	19	+	28162770	TF1	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10275839
38647742	38647765	19	+	28162770	TF1	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10275840
38700601	38700624	19	-	28162770	TF1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10275841
38700614	38700637	19	+	28162770	TF1	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10275842
38701051	38701074	19	+	28162770	TF1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10275843
38714516	38714539	19	+	28162770	TF1	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10275844
38717112	38717135	19	-	28162770	TF1	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10275845
38717151	38717174	19	+	28162770	TF1	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10275846
38723683	38723706	19	-	28162770	TF1	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10275847
38721554	38721577	19	+	28162770	SKM1	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10445204
38723701	38723724	19	+	28162770	SKM1	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.3155018257279293	[79]	[175]	3	hSpCas9	negative selection	10445205
38647742	38647765	19	+	28162770	SKM1	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.359658483964805	[44]	[61]	-3	hSpCas9	negative selection	10445206
38700601	38700624	19	-	28162770	SKM1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.33657487085176374	[49]	[69]	-3	hSpCas9	negative selection	10445207
38700614	38700637	19	+	28162770	SKM1	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.13868537795316838	[92]	[180]	1	hSpCas9	negative selection	10445208
38701051	38701074	19	+	28162770	SKM1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.2581008128286788	[22]	[33]	-2	hSpCas9	negative selection	10445209
38714516	38714539	19	+	28162770	SKM1	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.2381192944155654	[46]	[97]	2	hSpCas9	negative selection	10445210
38717112	38717135	19	-	28162770	SKM1	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.8458484399763732	[60]	[59]	-6	hSpCas9	negative selection	10445211
38717151	38717174	19	+	28162770	SKM1	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-3.576889200185474	[26]	[3]	-9	hSpCas9	negative selection	10445212
38723683	38723706	19	-	28162770	SKM1	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.27837999268174884	[58]	[85]	-2	hSpCas9	negative selection	10445213
38721554	38721577	19	+	28162770	SKM1	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10614570
38723701	38723724	19	+	28162770	SKM1	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.3155018257279293	[79]	[175]	3	hSpCas9	negative selection	10614571
38647742	38647765	19	+	28162770	SKM1	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.359658483964805	[44]	[61]	-3	hSpCas9	negative selection	10614572
38700601	38700624	19	-	28162770	SKM1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.33657487085176374	[49]	[69]	-3	hSpCas9	negative selection	10614573
38700614	38700637	19	+	28162770	SKM1	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.13868537795316838	[92]	[180]	1	hSpCas9	negative selection	10614574
38701051	38701074	19	+	28162770	SKM1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.2581008128286788	[22]	[33]	-2	hSpCas9	negative selection	10614575
38714516	38714539	19	+	28162770	SKM1	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.2381192944155654	[46]	[97]	2	hSpCas9	negative selection	10614576
38717112	38717135	19	-	28162770	SKM1	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.8458484399763732	[60]	[59]	-6	hSpCas9	negative selection	10614577
38717151	38717174	19	+	28162770	SKM1	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-3.576889200185474	[26]	[3]	-9	hSpCas9	negative selection	10614578
38723683	38723706	19	-	28162770	SKM1	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.27837999268174884	[58]	[85]	-2	hSpCas9	negative selection	10614579
38721554	38721577	19	+	28162770	PL21	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	0.8425876098712363	[122]	[95]	7	hSpCas9	negative selection	10783936
38723701	38723724	19	+	28162770	PL21	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.7502783566601195	[285]	[73]	-5	hSpCas9	negative selection	10783937
38647742	38647765	19	+	28162770	PL21	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.6151771137681639	[140]	[93]	5	hSpCas9	negative selection	10783938
38700601	38700624	19	-	28162770	PL21	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.5046187386204655	[182]	[112]	4	hSpCas9	negative selection	10783939
38700614	38700637	19	+	28162770	PL21	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	-0.3158755325143446	[285]	[99]	-2	hSpCas9	negative selection	10783940
38701051	38701074	19	+	28162770	PL21	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-1.0177654158548135	[106]	[22]	-6	hSpCas9	negative selection	10783941
38714516	38714539	19	+	28162770	PL21	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.02081591504475827	[153]	[67]	0	hSpCas9	negative selection	10783942
38717112	38717135	19	-	28162770	PL21	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.0541775742433648	[197]	[82]	0	hSpCas9	negative selection	10783943
38717151	38717174	19	+	28162770	PL21	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	0.6827403975807982	[72]	[50]	6	hSpCas9	negative selection	10783944
38723683	38723706	19	-	28162770	PL21	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	1.6430831103380485	[127]	[173]	9	hSpCas9	negative selection	10783945
38721554	38721577	19	+	28162770	P31FUJ	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	0.004889353304951882	[66]	[78]	0	hSpCas9	negative selection	10953302
38723701	38723724	19	+	28162770	P31FUJ	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.37917324794449747	[387]	[592]	4	hSpCas9	negative selection	10953303
38647742	38647765	19	+	28162770	P31FUJ	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.36018151089060646	[141]	[129]	-3	hSpCas9	negative selection	10953304
38700601	38700624	19	-	28162770	P31FUJ	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.25943733091784527	[163]	[160]	-2	hSpCas9	negative selection	10953305
38700614	38700637	19	+	28162770	P31FUJ	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.3521602963067776	[251]	[377]	4	hSpCas9	negative selection	10953306
38701051	38701074	19	+	28162770	P31FUJ	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.10898631283382676	[100]	[127]	1	hSpCas9	negative selection	10953307
38714516	38714539	19	+	28162770	P31FUJ	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	-0.12427774763620969	[127]	[137]	-1	hSpCas9	negative selection	10953308
38717112	38717135	19	-	28162770	P31FUJ	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.3463647632375785	[250]	[231]	-3	hSpCas9	negative selection	10953309
38717151	38717174	19	+	28162770	P31FUJ	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-4.787391056092016	[93]	[3]	-9	hSpCas9	negative selection	10953310
38723683	38723706	19	-	28162770	P31FUJ	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.058472023852065215	[217]	[245]	0	hSpCas9	negative selection	10953311
38721554	38721577	19	+	28162770	OCIAML5	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-0.48949649147928853	[41]	[53]	-3	hSpCas9	negative selection	11122668
38723701	38723724	19	+	28162770	OCIAML5	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.6495110353574982	[183]	[520]	5	hSpCas9	negative selection	11122669
38647742	38647765	19	+	28162770	OCIAML5	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	0.17490047673627218	[52]	[107]	1	hSpCas9	negative selection	11122670
38700601	38700624	19	-	28162770	OCIAML5	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.3680592435005059	[90]	[211]	3	hSpCas9	negative selection	11122671
38700614	38700637	19	+	28162770	OCIAML5	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	1.3298738067351568	[92]	[421]	9	hSpCas9	negative selection	11122672
38701051	38701074	19	+	28162770	OCIAML5	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.763269578900678	[46]	[143]	6	hSpCas9	negative selection	11122673
38714516	38714539	19	+	28162770	OCIAML5	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.9092187024976224	[99]	[338]	7	hSpCas9	negative selection	11122674
38717112	38717135	19	-	28162770	OCIAML5	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	0.22593594113727622	[116]	[246]	2	hSpCas9	negative selection	11122675
38717151	38717174	19	+	28162770	OCIAML5	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-6.099994084307582	[37]	[0]	-9	hSpCas9	negative selection	11122676
38723683	38723706	19	-	28162770	OCIAML5	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.2612749022119478	[103]	[224]	2	hSpCas9	negative selection	11122677
38721554	38721577	19	+	28162770	EOL1	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.23644410510177	[160]	[35]	-7	hSpCas9	negative selection	11292034
38723701	38723724	19	+	28162770	EOL1	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.12866403461579215	[358]	[172]	-1	hSpCas9	negative selection	11292035
38647742	38647765	19	+	28162770	EOL1	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.07545222842946553	[201]	[100]	0	hSpCas9	negative selection	11292036
38700601	38700624	19	-	28162770	EOL1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.6264664186375398	[299]	[243]	5	hSpCas9	negative selection	11292037
38700614	38700637	19	+	28162770	EOL1	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.06640040441476813	[541]	[298]	0	hSpCas9	negative selection	11292038
38701051	38701074	19	+	28162770	EOL1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	1.1818798180401449	[168]	[201]	8	hSpCas9	negative selection	11292039
38714516	38714539	19	+	28162770	EOL1	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.4856635303373231	[182]	[134]	4	hSpCas9	negative selection	11292040
38717112	38717135	19	-	28162770	EOL1	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.47841689540773424	[237]	[89]	-4	hSpCas9	negative selection	11292041
38717151	38717174	19	+	28162770	EOL1	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-4.479174414480475	[126]	[2]	-9	hSpCas9	negative selection	11292042
38723683	38723706	19	-	28162770	EOL1	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	1.6499914958415212	[175]	[290]	9	hSpCas9	negative selection	11292043
38721554	38721577	19	+	28162770	MOLM13	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.290555940032079	[202]	[59]	-6	hSpCas9	negative selection	11461400
38723701	38723724	19	+	28162770	MOLM13	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.09786251521074252	[372]	[251]	0	hSpCas9	negative selection	11461401
38647742	38647765	19	+	28162770	MOLM13	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.4700496503231697	[181]	[94]	-3	hSpCas9	negative selection	11461402
38700601	38700624	19	-	28162770	MOLM13	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.32784142143688216	[226]	[205]	2	hSpCas9	negative selection	11461403
38700614	38700637	19	+	28162770	MOLM13	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.2757384618672948	[416]	[364]	2	hSpCas9	negative selection	11461404
38701051	38701074	19	+	28162770	MOLM13	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	-0.08980018902647391	[130]	[88]	0	hSpCas9	negative selection	11461405
38714516	38714539	19	+	28162770	MOLM13	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.22213296714262043	[248]	[209]	1	hSpCas9	negative selection	11461406
38717112	38717135	19	-	28162770	MOLM13	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.17943900013695085	[259]	[165]	-1	hSpCas9	negative selection	11461407
38717151	38717174	19	+	28162770	MOLM13	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-4.504803272459686	[156]	[4]	-9	hSpCas9	negative selection	11461408
38723683	38723706	19	-	28162770	MOLM13	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.5518288530699266	[220]	[108]	-3	hSpCas9	negative selection	11461409
38721554	38721577	19	+	28162770	HEL	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.4233503584574154	[133]	[31]	-7	hSpCas9	negative selection	11630766
38723701	38723724	19	+	28162770	HEL	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.8596973672861769	[227]	[264]	7	hSpCas9	negative selection	11630767
38647742	38647765	19	+	28162770	HEL	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	1.5438238059276697	[165]	[309]	9	hSpCas9	negative selection	11630768
38700601	38700624	19	-	28162770	HEL	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.18515563775542837	[194]	[141]	1	hSpCas9	negative selection	11630769
38700614	38700637	19	+	28162770	HEL	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	-1.1338229365116441	[393]	[114]	-6	hSpCas9	negative selection	11630770
38701051	38701074	19	+	28162770	HEL	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.13326653086346407	[120]	[84]	1	hSpCas9	negative selection	11630771
38714516	38714539	19	+	28162770	HEL	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.8526619013745884	[165]	[191]	7	hSpCas9	negative selection	11630772
38717112	38717135	19	-	28162770	HEL	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	0.6013980366194573	[176]	[171]	5	hSpCas9	negative selection	11630773
38717151	38717174	19	+	28162770	HEL	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-3.9719710121148513	[97]	[3]	-9	hSpCas9	negative selection	11630774
38723683	38723706	19	-	28162770	HEL	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	3.2034537864748356	[159]	[943]	9	hSpCas9	negative selection	11630775
38721554	38721577	19	+	28162770	MV411	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-1.1585548088930617	[105]	[39]	-6	hSpCas9	negative selection	11800132
38723701	38723724	19	+	28162770	MV411	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	-0.139585572326472	[254]	[194]	-1	hSpCas9	negative selection	11800133
38647742	38647765	19	+	28162770	MV411	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.4895280433834308	[119]	[71]	-4	hSpCas9	negative selection	11800134
38700601	38700624	19	-	28162770	MV411	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	-0.775646062330266	[188]	[92]	-5	hSpCas9	negative selection	11800135
38700614	38700637	19	+	28162770	MV411	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	-0.5787599774868261	[288]	[162]	-4	hSpCas9	negative selection	11800136
38701051	38701074	19	+	28162770	MV411	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.31302589241035217	[85]	[89]	2	hSpCas9	negative selection	11800137
38714516	38714539	19	+	28162770	MV411	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	-0.4765013630871913	[146]	[88]	-4	hSpCas9	negative selection	11800138
38717112	38717135	19	-	28162770	MV411	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.541058344023513	[151]	[87]	-4	hSpCas9	negative selection	11800139
38717151	38717174	19	+	28162770	MV411	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-2.702521766717629	[84]	[10]	-9	hSpCas9	negative selection	11800140
38723683	38723706	19	-	28162770	MV411	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	-0.3412480359810982	[193]	[128]	-3	hSpCas9	negative selection	11800141
38721554	38721577	19	+	28162770	MONOMAC1	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	0.7220431575568789	[54]	[103]	7	hSpCas9	negative selection	11969498
38723701	38723724	19	+	28162770	MONOMAC1	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.06910346964206182	[231]	[278]	0	hSpCas9	negative selection	11969499
38647742	38647765	19	+	28162770	MONOMAC1	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.6171453358858197	[94]	[70]	-5	hSpCas9	negative selection	11969500
38700601	38700624	19	-	28162770	MONOMAC1	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	1.3879256536616025	[128]	[386]	9	hSpCas9	negative selection	11969501
38700614	38700637	19	+	28162770	MONOMAC1	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.10929439277678998	[185]	[229]	1	hSpCas9	negative selection	11969502
38701051	38701074	19	+	28162770	MONOMAC1	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.2757161500755776	[48]	[67]	2	hSpCas9	negative selection	11969503
38714516	38714539	19	+	28162770	MONOMAC1	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.479073541719798	[91]	[146]	5	hSpCas9	negative selection	11969504
38717112	38717135	19	-	28162770	MONOMAC1	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-0.3063842432479146	[136]	[126]	-3	hSpCas9	negative selection	11969505
38717151	38717174	19	+	28162770	MONOMAC1	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-3.5189649419469164	[39]	[3]	-9	hSpCas9	negative selection	11969506
38723683	38723706	19	-	28162770	MONOMAC1	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.5166589677838054	[74]	[122]	5	hSpCas9	negative selection	11969507
38721554	38721577	19	+	28162770	OCIAML2	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-0.041786526438287064	[12]	[69]	0	hSpCas9	negative selection	12138864
38723701	38723724	19	+	28162770	OCIAML2	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.3412978266052669	[44]	[315]	3	hSpCas9	negative selection	12138865
38647742	38647765	19	+	28162770	OCIAML2	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-0.022169324425867054	[23]	[130]	0	hSpCas9	negative selection	12138866
38700601	38700624	19	-	28162770	OCIAML2	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.7517625960942868	[29]	[279]	7	hSpCas9	negative selection	12138867
38700614	38700637	19	+	28162770	OCIAML2	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.4314437540685816	[39]	[298]	4	hSpCas9	negative selection	12138868
38701051	38701074	19	+	28162770	OCIAML2	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	0.9353625344336758	[14]	[158]	8	hSpCas9	negative selection	12138869
38714516	38714539	19	+	28162770	OCIAML2	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	-0.567305844653835	[26]	[100]	-4	hSpCas9	negative selection	12138870
38717112	38717135	19	-	28162770	OCIAML2	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	0.1503119725845617	[32]	[202]	1	hSpCas9	negative selection	12138871
38717151	38717174	19	+	28162770	OCIAML2	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-2.750737744434897	[16]	[13]	-9	hSpCas9	negative selection	12138872
38723683	38723706	19	-	28162770	OCIAML2	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.9530517684459341	[25]	[278]	8	hSpCas9	negative selection	12138873
38721554	38721577	19	+	28162770	OCIAML3	viability	GAAGCACCGGGACTACGAGACGG	ACTN4	ENSG00000130402	-0.40136256238176704	[27]	[63]	-3	hSpCas9	negative selection	12308230
38723701	38723724	19	+	28162770	OCIAML3	viability	TAGTCGCAGGGAAGCCCTGGAGG	ACTN4	ENSG00000130402	0.5710516059463333	[65]	[295]	5	hSpCas9	negative selection	12308231
38647742	38647765	19	+	28162770	OCIAML3	viability	CGGAATGGTGGACTACCACGCGG	ACTN4	ENSG00000130402	-1.6741779890081463	[36]	[34]	-8	hSpCas9	negative selection	12308232
38700601	38700624	19	-	28162770	OCIAML3	viability	GGAGTTGCACCATGCCGTGAAGG	ACTN4	ENSG00000130402	0.5718012526459174	[38]	[174]	5	hSpCas9	negative selection	12308233
38700614	38700637	19	+	28162770	OCIAML3	viability	GTGCAACTCCCACCTGCGGAAGG	ACTN4	ENSG00000130402	0.2103572391276295	[68]	[240]	2	hSpCas9	negative selection	12308234
38701051	38701074	19	+	28162770	OCIAML3	viability	CAACAATGTGAACAAAGCGCTGG	ACTN4	ENSG00000130402	1.4251859249091479	[27]	[226]	9	hSpCas9	negative selection	12308235
38714516	38714539	19	+	28162770	OCIAML3	viability	AGAGAACGAGCACCTGATGGAGG	ACTN4	ENSG00000130402	0.6460434475087914	[28]	[136]	6	hSpCas9	negative selection	12308236
38717112	38717135	19	-	28162770	OCIAML3	viability	GCACACGGTCCTCCAGCCAGGGG	ACTN4	ENSG00000130402	-1.1371499653506922	[50]	[69]	-7	hSpCas9	negative selection	12308237
38717151	38717174	19	+	28162770	OCIAML3	viability	GGAGATGCAGCAGAAGCTGGAGG	ACTN4	ENSG00000130402	-5.681470481574503	[16]	[0]	-9	hSpCas9	negative selection	12308238
38723683	38723706	19	-	28162770	OCIAML3	viability	GACTATGTGTCAGAGAGCCGAGG	ACTN4	ENSG00000130402	0.9232680528854182	[39]	[228]	7	hSpCas9	negative selection	12308239