Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57679
• Symbol: ALS2
• Description: alsin Rho guanine nucleotide exchange factor ALS2

DataSource: http://genomecrispr.dkfz.de/#!/results/ALS2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
201768865	201768888	2	-	26472758	Jiyoye	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	1.1707351856837926	[42]	[72]	7	hSpCas9	negative selection	5698
201767358	201767381	2	-	26472758	Jiyoye	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.4382022771264982	[91]	[93]	3	hSpCas9	negative selection	5699
201767285	201767308	2	-	26472758	Jiyoye	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	3.9921378822270293	[0]	[11]	9	hSpCas9	negative selection	5700
201761157	201761180	2	+	26472758	Jiyoye	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.18418489041343356	[225]	[149]	-1	hSpCas9	negative selection	5701
201761776	201761799	2	-	26472758	Jiyoye	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	5.214530303563477	[0]	[27]	9	hSpCas9	negative selection	5702
201761541	201761564	2	+	26472758	Jiyoye	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.27390885064240933	[135]	[123]	2	hSpCas9	negative selection	5703
201761368	201761391	2	-	26472758	Jiyoye	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	-0.1495902273846309	[227]	[154]	-1	hSpCas9	negative selection	5704
201761339	201761362	2	+	26472758	Jiyoye	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.8696648238529511	[62]	[25]	-6	hSpCas9	negative selection	5705
201760928	201760951	2	+	26472758	Jiyoye	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.2535546268332476	[214]	[135]	-2	hSpCas9	negative selection	5706
201760873	201760896	2	+	26472758	Jiyoye	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.23340831376916685	[140]	[124]	1	hSpCas9	negative selection	5707
201768865	201768888	2	-	26472758	KBM7	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.9120927111762798	[298,315]	[440,124]	8	hSpCas9	negative selection	196816
201767358	201767381	2	-	26472758	KBM7	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.23861802917151748	[499,526]	[314,261]	2	hSpCas9	negative selection	196817
201767285	201767308	2	-	26472758	KBM7	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-0.8303249630375067	[33,99]	[14,21]	-6	hSpCas9	negative selection	196818
201761157	201761180	2	+	26472758	KBM7	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.38742105808403315	[688,664]	[716,149]	4	hSpCas9	negative selection	196819
201761776	201761799	2	-	26472758	KBM7	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-1.2832935733205018	[101,74]	[27,6]	-7	hSpCas9	negative selection	196820
201761541	201761564	2	+	26472758	KBM7	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.8434729749961526	[587,331]	[398,360]	8	hSpCas9	negative selection	196821
201761368	201761391	2	-	26472758	KBM7	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.35118702790160755	[597,658]	[471,298]	4	hSpCas9	negative selection	196822
201761339	201761362	2	+	26472758	KBM7	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.4577850012130401	[340,327]	[164,69]	-4	hSpCas9	negative selection	196823
201760928	201760951	2	+	26472758	KBM7	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.16315771845633753	[909,896]	[277,472]	-1	hSpCas9	negative selection	196824
201760873	201760896	2	+	26472758	KBM7	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.8160036820001253	[536,666]	[595,425]	8	hSpCas9	negative selection	196825
201768865	201768888	2	-	26472758	Raji	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.06739086573010866	[148]	[32]	0	hSpCas9	negative selection	387934
201767358	201767381	2	-	26472758	Raji	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.052559510629078154	[294]	[70]	0	hSpCas9	negative selection	387935
201767285	201767308	2	-	26472758	Raji	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	1.4122381169020204	[67]	[41]	9	hSpCas9	negative selection	387936
201761157	201761180	2	+	26472758	Raji	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.7183412446277002	[274]	[104]	6	hSpCas9	negative selection	387937
201761776	201761799	2	-	26472758	Raji	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	0.6923460360947558	[31]	[11]	6	hSpCas9	negative selection	387938
201761541	201761564	2	+	26472758	Raji	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.7837643236891718	[318]	[42]	-5	hSpCas9	negative selection	387939
201761368	201761391	2	-	26472758	Raji	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.3808668904384242	[320]	[96]	3	hSpCas9	negative selection	387940
201761339	201761362	2	+	26472758	Raji	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	0.1940951685669302	[225]	[59]	1	hSpCas9	negative selection	387941
201760928	201760951	2	+	26472758	Raji	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.2849338874051607	[545]	[103]	-2	hSpCas9	negative selection	387942
201760873	201760896	2	+	26472758	Raji	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.16708978149786718	[283]	[73]	1	hSpCas9	negative selection	387943
201768865	201768888	2	-	26472758	K562	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.26155986048784063	[250]	[253]	2	hSpCas9	negative selection	579052
201767358	201767381	2	-	26472758	K562	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-1.444593643276832	[502]	[155]	-6	hSpCas9	negative selection	579053
201767285	201767308	2	-	26472758	K562	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	0.09686153925258933	[71]	[64]	0	hSpCas9	negative selection	579054
201761157	201761180	2	+	26472758	K562	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.4047084322964577	[433]	[484]	3	hSpCas9	negative selection	579055
201761776	201761799	2	-	26472758	K562	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-0.15291676987893776	[53]	[40]	-1	hSpCas9	negative selection	579056
201761541	201761564	2	+	26472758	K562	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.8046663620350561	[313]	[462]	6	hSpCas9	negative selection	579057
201761368	201761391	2	-	26472758	K562	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.8766869431659599	[419]	[650]	7	hSpCas9	negative selection	579058
201761339	201761362	2	+	26472758	K562	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-2.3710458614520533	[238]	[38]	-8	hSpCas9	negative selection	579059
201760928	201760951	2	+	26472758	K562	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.7526276440617871	[726]	[1033]	6	hSpCas9	negative selection	579060
201760873	201760896	2	+	26472758	K562	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.4449786412896977	[408]	[939]	9	hSpCas9	negative selection	579061
201749711	201749734	2	-	26627737	DLD1	viability	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.05714748368167594	[360]	[118,143,93]	0	hSpCas9	negative selection	809947
201753154	201753177	2	+	26627737	DLD1	viability	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.5742946802142239	[508]	[286,222,204]	6	hSpCas9	negative selection	809948
201757504	201757527	2	-	26627737	DLD1	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	1.085126433903421	[441]	[333,235,304]	8	hSpCas9	negative selection	809949
201761541	201761564	2	+	26627737	DLD1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.19802080778080988	[191]	[55,8,84]	-2	hSpCas9	negative selection	809950
201767242	201767265	2	+	26627737	DLD1	viability	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.6450813877564759	[392]	[79,90,66]	-6	hSpCas9	negative selection	809951
201768865	201768888	2	-	26627737	DLD1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.8876898026903991	[214]	[133,104,131]	8	hSpCas9	negative selection	809952
201749711	201749734	2	-	26627737	GBM cells	viability after 5 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.7228151058231727	[160]	[113,170]	8	hSpCas9	negative selection	892262
201753154	201753177	2	+	26627737	GBM cells	viability after 5 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.14120120245305467	[606]	[341,375]	2	hSpCas9	negative selection	892263
201757504	201757527	2	-	26627737	GBM cells	viability after 5 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.3590110967831811	[393]	[274,266]	5	hSpCas9	negative selection	892264
201761541	201761564	2	+	26627737	GBM cells	viability after 5 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.10108612511431425	[97]	[84,12]	-1	hSpCas9	negative selection	892265
201767242	201767265	2	+	26627737	GBM cells	viability after 5 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.5842951270347374	[129]	[43,48]	-7	hSpCas9	negative selection	892266
201768865	201768888	2	-	26627737	GBM cells	viability after 5 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.6120480443916938	[284]	[67,131]	-7	hSpCas9	negative selection	892267
201749711	201749734	2	-	26627737	GBM cells	viability after 13 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.7143179114058067	[160]	[171,119]	8	hSpCas9	negative selection	974577
201753154	201753177	2	+	26627737	GBM cells	viability after 13 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.2023525272562725	[606]	[384,373]	2	hSpCas9	negative selection	974578
201757504	201757527	2	-	26627737	GBM cells	viability after 13 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.39247542872798247	[393]	[332,237]	5	hSpCas9	negative selection	974579
201761541	201761564	2	+	26627737	GBM cells	viability after 13 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.8269390766545466	[97]	[122,70]	8	hSpCas9	negative selection	974580
201767242	201767265	2	+	26627737	GBM cells	viability after 13 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.29182584843275916	[129]	[50,62]	-3	hSpCas9	negative selection	974581
201768865	201768888	2	-	26627737	GBM cells	viability after 13 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-1.2634626722354603	[284]	[59,67]	-8	hSpCas9	negative selection	974582
201749711	201749734	2	-	26627737	GBM cells	viability after 21 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.6496867465307692	[160]	[131,141]	6	hSpCas9	negative selection	1056892
201753154	201753177	2	+	26627737	GBM cells	viability after 21 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.3692020564233842	[606]	[438,413]	4	hSpCas9	negative selection	1056893
201757504	201757527	2	-	26627737	GBM cells	viability after 21 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.09514353519818519	[393]	[236,220]	1	hSpCas9	negative selection	1056894
201761541	201761564	2	+	26627737	GBM cells	viability after 21 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.20438424496271468	[97]	[64,57]	2	hSpCas9	negative selection	1056895
201767242	201767265	2	+	26627737	GBM cells	viability after 21 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.5274246692975879	[129]	[48,48]	-5	hSpCas9	negative selection	1056896
201768865	201768888	2	-	26627737	GBM cells	viability after 21 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-1.1064420133361428	[284]	[73,69]	-7	hSpCas9	negative selection	1056897
201749711	201749734	2	-	26627737	RPE1	viability after 9 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.24927946292297262	[558]	[152,278]	1	hSpCas9	negative selection	1139207
201753154	201753177	2	+	26627737	RPE1	viability after 9 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.11500673179925358	[2085]	[677,744]	0	hSpCas9	negative selection	1139208
201757504	201757527	2	-	26627737	RPE1	viability after 9 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.056362286178201826	[1497]	[505,463]	0	hSpCas9	negative selection	1139209
201761541	201761564	2	+	26627737	RPE1	viability after 9 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	1.378178253291023	[230]	[118,276]	7	hSpCas9	negative selection	1139210
201767242	201767265	2	+	26627737	RPE1	viability after 9 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-3.7398187025703096	[1278]	[15,47]	-9	hSpCas9	negative selection	1139211
201768865	201768888	2	-	26627737	RPE1	viability after 9 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.5109340046314391	[515]	[77,158]	-4	hSpCas9	negative selection	1139212
201749711	201749734	2	-	26627737	RPE1	viability after 12 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.7337065449128897	[558]	[172,330]	5	hSpCas9	negative selection	1221522
201753154	201753177	2	+	26627737	RPE1	viability after 12 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.3466523263894996	[2085]	[632,796]	2	hSpCas9	negative selection	1221523
201757504	201757527	2	-	26627737	RPE1	viability after 12 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.022238363479965773	[1497]	[381,436]	0	hSpCas9	negative selection	1221524
201761541	201761564	2	+	26627737	RPE1	viability after 12 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.63232735913976	[230]	[51,142]	4	hSpCas9	negative selection	1221525
201767242	201767265	2	+	26627737	RPE1	viability after 12 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-3.0591165696622675	[1278]	[48,32]	-9	hSpCas9	negative selection	1221526
201768865	201768888	2	-	26627737	RPE1	viability after 12 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.3694175130413083	[515]	[66,149]	-3	hSpCas9	negative selection	1221527
201749711	201749734	2	-	26627737	RPE1	viability after 15 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.5920274064097676	[558]	[161,311]	4	hSpCas9	negative selection	1303837
201753154	201753177	2	+	26627737	RPE1	viability after 15 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.5589297581059502	[2085]	[936,803]	3	hSpCas9	negative selection	1303838
201757504	201757527	2	-	26627737	RPE1	viability after 15 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	-0.2314078936982653	[1497]	[222,493]	-1	hSpCas9	negative selection	1303839
201761541	201761564	2	+	26627737	RPE1	viability after 15 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.8443205783822458	[230]	[42,188]	5	hSpCas9	negative selection	1303840
201767242	201767265	2	+	26627737	RPE1	viability after 15 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-3.1673646136600517	[1278]	[24,54]	-9	hSpCas9	negative selection	1303841
201768865	201768888	2	-	26627737	RPE1	viability after 15 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-1.0405129987446933	[515]	[44,95]	-6	hSpCas9	negative selection	1303842
201749711	201749734	2	-	26627737	RPE1	viability after 18 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.6853262474562559	[558]	[215,270]	4	hSpCas9	negative selection	1386152
201753154	201753177	2	+	26627737	RPE1	viability after 18 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.3366678398373999	[2085]	[649,775]	2	hSpCas9	negative selection	1386153
201757504	201757527	2	-	26627737	RPE1	viability after 18 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	-0.19894525963739618	[1497]	[313,392]	-1	hSpCas9	negative selection	1386154
201761541	201761564	2	+	26627737	RPE1	viability after 18 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	1.2807095336762295	[230]	[91,214]	7	hSpCas9	negative selection	1386155
201767242	201767265	2	+	26627737	RPE1	viability after 18 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-3.040606730450828	[1278]	[54,27]	-9	hSpCas9	negative selection	1386156
201768865	201768888	2	-	26627737	RPE1	viability after 18 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.026974691570534337	[515]	[199,68]	0	hSpCas9	negative selection	1386157
201749711	201749734	2	-	26627737	HeLa	viability after 8 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.04436122660437569	[262]	[190,103,77]	0	hSpCas9	negative selection	1468467
201753154	201753177	2	+	26627737	HeLa	viability after 8 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.4553166742527094	[702]	[575,197,511]	4	hSpCas9	negative selection	1468468
201757504	201757527	2	-	26627737	HeLa	viability after 8 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.1747564693046184	[604]	[372,205,326]	1	hSpCas9	negative selection	1468469
201761541	201761564	2	+	26627737	HeLa	viability after 8 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.03207593044513857	[211]	[40,145,73]	0	hSpCas9	negative selection	1468470
201767242	201767265	2	+	26627737	HeLa	viability after 8 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	0.6943685644658157	[128]	[112,67,95]	6	hSpCas9	negative selection	1468471
201768865	201768888	2	-	26627737	HeLa	viability after 8 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.42618183419880273	[600]	[209,237,142]	-4	hSpCas9	negative selection	1468472
201749711	201749734	2	-	26627737	HeLa	viability after 12 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.2582812594442134	[262]	[160,128,100]	2	hSpCas9	negative selection	1550782
201753154	201753177	2	+	26627737	HeLa	viability after 12 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.2898613007539991	[702]	[264,391,401]	2	hSpCas9	negative selection	1550783
201757504	201757527	2	-	26627737	HeLa	viability after 12 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.19575544851695692	[604]	[217,324,309]	1	hSpCas9	negative selection	1550784
201761541	201761564	2	+	26627737	HeLa	viability after 12 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.05970624694409399	[211]	[149,87,37]	0	hSpCas9	negative selection	1550785
201767242	201767265	2	+	26627737	HeLa	viability after 12 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	0.43997357482770894	[128]	[27,106,76]	4	hSpCas9	negative selection	1550786
201768865	201768888	2	-	26627737	HeLa	viability after 12 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.9384000246452618	[600]	[155,68,170]	-7	hSpCas9	negative selection	1550787
201749711	201749734	2	-	26627737	HeLa	viability after 15 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.3389514098659575	[262]	[111,153,140]	3	hSpCas9	negative selection	1633097
201753154	201753177	2	+	26627737	HeLa	viability after 15 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.1676103867946005	[702]	[400,268,290]	1	hSpCas9	negative selection	1633098
201757504	201757527	2	-	26627737	HeLa	viability after 15 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.26152847755567565	[604]	[274,339,268]	2	hSpCas9	negative selection	1633099
201761541	201761564	2	+	26627737	HeLa	viability after 15 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.029531278959878615	[211]	[151,37,60]	0	hSpCas9	negative selection	1633100
201767242	201767265	2	+	26627737	HeLa	viability after 15 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	0.8423502523396841	[128]	[72,15,201]	6	hSpCas9	negative selection	1633101
201768865	201768888	2	-	26627737	HeLa	viability after 15 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.21534359477849674	[600]	[277,146,205]	-2	hSpCas9	negative selection	1633102
201749711	201749734	2	-	26627737	HeLa	viability after 18 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.31375229619318007	[262]	[74,121,140]	2	hSpCas9	negative selection	1715412
201753154	201753177	2	+	26627737	HeLa	viability after 18 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.1545168409646902	[702]	[259,226,290]	1	hSpCas9	negative selection	1715413
201757504	201757527	2	-	26627737	HeLa	viability after 18 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.23991663805753594	[604]	[169,288,268]	2	hSpCas9	negative selection	1715414
201761541	201761564	2	+	26627737	HeLa	viability after 18 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.04327178074013416	[211]	[95,36,60]	0	hSpCas9	negative selection	1715415
201767242	201767265	2	+	26627737	HeLa	viability after 18 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	0.7764394681578265	[128]	[40,12,201]	6	hSpCas9	negative selection	1715416
201768865	201768888	2	-	26627737	HeLa	viability after 18 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.15167767394817733	[600]	[203,122,205]	-1	hSpCas9	negative selection	1715417
201749711	201749734	2	-	26627737	HCT116	viability after 6 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	1.309794479295427	[649]	[48,365]	7	hSpCas9	negative selection	1797727
201753154	201753177	2	+	26627737	HCT116	viability after 6 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	-0.17254687543620606	[1051]	[245,91]	-1	hSpCas9	negative selection	1797728
201757504	201757527	2	-	26627737	HCT116	viability after 6 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.2289438876276998	[1154]	[206,215]	1	hSpCas9	negative selection	1797729
201761541	201761564	2	+	26627737	HCT116	viability after 6 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	2.4260205021373045	[79]	[142,25]	9	hSpCas9	negative selection	1797730
201767242	201767265	2	+	26627737	HCT116	viability after 6 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	2.4636065753330225	[30]	[71,1]	9	hSpCas9	negative selection	1797731
201768865	201768888	2	-	26627737	HCT116	viability after 6 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-4.0233262437772055	[500]	[9,1]	-9	hSpCas9	negative selection	1797732
201749711	201749734	2	-	26627737	HCT116	viability after 8 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.670893460512934	[317]	[116,159,53]	-7	hSpCas9	negative selection	1880042
201753154	201753177	2	+	26627737	HCT116	viability after 8 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.13747892322167288	[639]	[375,437,349]	1	hSpCas9	negative selection	1880043
201757504	201757527	2	-	26627737	HCT116	viability after 8 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.2519475058224485	[483]	[350,337,264]	3	hSpCas9	negative selection	1880044
201761541	201761564	2	+	26627737	HCT116	viability after 8 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.07899838418561034	[168]	[109,61,122]	0	hSpCas9	negative selection	1880045
201767242	201767265	2	+	26627737	HCT116	viability after 8 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.8888664073015821	[324]	[67,155,65]	-8	hSpCas9	negative selection	1880046
201768865	201768888	2	-	26627737	HCT116	viability after 8 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.3270927042005611	[241]	[135,173,190]	3	hSpCas9	negative selection	1880047
201749711	201749734	2	-	26627737	HCT116	viability after 9 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.6661223285218744	[649]	[38,164]	-5	hSpCas9	negative selection	1962357
201753154	201753177	2	+	26627737	HCT116	viability after 9 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	-0.6036019337945233	[1051]	[271,115]	-4	hSpCas9	negative selection	1962358
201757504	201757527	2	-	26627737	HCT116	viability after 9 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.2970923387919976	[1154]	[350,400]	2	hSpCas9	negative selection	1962359
201761541	201761564	2	+	26627737	HCT116	viability after 9 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	3.84769450785255	[79]	[206,386]	9	hSpCas9	negative selection	1962360
201767242	201767265	2	+	26627737	HCT116	viability after 9 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	3.502752853544496	[30]	[104,84]	9	hSpCas9	negative selection	1962361
201768865	201768888	2	-	26627737	HCT116	viability after 9 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.47492858755673567	[500]	[131,67]	-3	hSpCas9	negative selection	1962362
201749711	201749734	2	-	26627737	HCT116	viability after 12 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.374377044479166	[317]	[136,167,81]	-4	hSpCas9	negative selection	2044672
201753154	201753177	2	+	26627737	HCT116	viability after 12 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	-0.1868600479503838	[639]	[262,324,301]	-2	hSpCas9	negative selection	2044673
201757504	201757527	2	-	26627737	HCT116	viability after 12 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	-0.11453393072866302	[483]	[240,263,199]	-1	hSpCas9	negative selection	2044674
201761541	201761564	2	+	26627737	HCT116	viability after 12 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.030950089968654337	[168]	[76,100,83]	0	hSpCas9	negative selection	2044675
201767242	201767265	2	+	26627737	HCT116	viability after 12 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.902775095095468	[324]	[67,86,120]	-7	hSpCas9	negative selection	2044676
201768865	201768888	2	-	26627737	HCT116	viability after 12 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.1671499220115518	[241]	[113,186,130]	1	hSpCas9	negative selection	2044677
201749711	201749734	2	-	26627737	HCT116	viability after 15 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.5957850458470904	[317]	[130,131,100]	-6	hSpCas9	negative selection	2126987
201753154	201753177	2	+	26627737	HCT116	viability after 15 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.0058170860504001	[639]	[319,400,379]	0	hSpCas9	negative selection	2126988
201757504	201757527	2	-	26627737	HCT116	viability after 15 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.08741102194506523	[483]	[339,305,245]	0	hSpCas9	negative selection	2126989
201761541	201761564	2	+	26627737	HCT116	viability after 15 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.6905553394051813	[168]	[269,80,132]	6	hSpCas9	negative selection	2126990
201767242	201767265	2	+	26627737	HCT116	viability after 15 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.7947365158903857	[324]	[70,112,133]	-7	hSpCas9	negative selection	2126991
201768865	201768888	2	-	26627737	HCT116	viability after 15 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.25769408021430823	[241]	[150,126,217]	2	hSpCas9	negative selection	2126992
201749711	201749734	2	-	26627737	HCT116	viability after 18 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.7043020302177494	[317]	[107,114,56]	-6	hSpCas9	negative selection	2209302
201753154	201753177	2	+	26627737	HCT116	viability after 18 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.10798246584344917	[639]	[241,416,335]	1	hSpCas9	negative selection	2209303
201757504	201757527	2	-	26627737	HCT116	viability after 18 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.6480164558248273	[483]	[420,429,238]	5	hSpCas9	negative selection	2209304
201761541	201761564	2	+	26627737	HCT116	viability after 18 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.2310466400383313	[168]	[78,12,122]	-2	hSpCas9	negative selection	2209305
201767242	201767265	2	+	26627737	HCT116	viability after 18 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-1.5167153594542215	[324]	[32,112,12]	-8	hSpCas9	negative selection	2209306
201768865	201768888	2	-	26627737	HCT116	viability after 18 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.2651794316411781	[241]	[135,157,125]	2	hSpCas9	negative selection	2209307
201772276	201772299	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTTGTTGTTGTTGTTGTTAAG	ALS2	ENSG00000003393	-1.2553913082042603	[104,179]	[19,4]	-7	dCas9-VP64	positive selection	2401227
201732523	201732546	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCCCAG	ALS2	ENSG00000003393	0.5268875283082193	[1,6]	[1,0]	2	dCas9-VP64	positive selection	2458545
201772276	201772299	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTTGTTGTTGTTGTTGTTAAG	ALS2	ENSG00000003393	-0.6691815338040683	[248,92]	[41,27]	-6	dCas9-VP64	positive selection	2496482
201732523	201732546	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCCCAG	ALS2	ENSG00000003393	1.3449939631950025	[38,32]	[23,34]	7	dCas9-VP64	positive selection	2553800
201761215	201761238	2	-	27260157	DLD1	viability	GACAGTCATTGTTGCCCATTAGG	ALS2	ENSG00000003393	-0.166227582294011	[]	[]	-1	hSpCas9	negative selection	2574580
201767327	201767350	2	-	27260157	DLD1	viability	CTGGTCCATATCTGGCAGGCAGG	ALS2	ENSG00000003393	0.076676991095066	[]	[]	3	hSpCas9	negative selection	2577757
201761541	201761564	2	+	27260157	DLD1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.394930982456867	[]	[]	4	hSpCas9	negative selection	2578236
201761591	201761614	2	+	27260157	DLD1	viability	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	0.18195937574937	[]	[]	3	hSpCas9	negative selection	2578923
201761647	201761670	2	-	27260157	DLD1	viability	AATGGTGTCGCGTACATGTGGGG	ALS2	ENSG00000003393	-0.975614862846468	[]	[]	-7	hSpCas9	negative selection	2584157
201767241	201767264	2	+	27260157	DLD1	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.0748238746402786	[]	[]	3	hSpCas9	negative selection	2584207
201761368	201761391	2	-	27260157	DLD1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.172706286935536	[]	[]	3	hSpCas9	negative selection	2585700
201761766	201761789	2	+	27260157	DLD1	viability	CTCCACTGGTCCACTTCTCCAGG	ALS2	ENSG00000003393	0.10824507480787	[]	[]	3	hSpCas9	negative selection	2587262
201761415	201761438	2	+	27260157	DLD1	viability	TTGCGGCTTTGTCACTGGGAAGG	ALS2	ENSG00000003393	-0.997237252314952	[]	[]	-7	hSpCas9	negative selection	2587604
201768873	201768896	2	+	27260157	DLD1	viability	TCTTTGAGTCCATCGGTCAGTGG	ALS2	ENSG00000003393	-0.322158039298973	[]	[]	-3	hSpCas9	negative selection	2587651
201753180	201753203	2	-	27260157	DLD1	viability	GTAATCCATCTGGAGGCAGGTGG	ALS2	ENSG00000003393	-0.258543369666862	[]	[]	-2	hSpCas9	negative selection	2604203
201746640	201746663	2	-	27260157	DLD1	viability	GTTATATTACAGTGGCCGACAGG	ALS2	ENSG00000003393	-0.223518638576572	[]	[]	-2	hSpCas9	negative selection	2605600
201768882	201768905	2	-	27260157	DLD1	viability	GGAGTGTTCCCACTGACCGATGG	ALS2	ENSG00000003393	-0.511410593316028	[]	[]	-4	hSpCas9	negative selection	2612925
201761609	201761632	2	+	27260157	DLD1	viability	GCTGGTTGGCTACTGCACACTGG	ALS2	ENSG00000003393	-1.65319377649678	[]	[]	-8	hSpCas9	negative selection	2613787
201757504	201757527	2	-	27260157	DLD1	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.644735407203079	[]	[]	8	hSpCas9	negative selection	2616318
201761411	201761434	2	-	27260157	DLD1	viability	CCCAGTGACAAAGCCGCAAAAGG	ALS2	ENSG00000003393	0.201759891198878	[]	[]	3	hSpCas9	negative selection	2620121
201761445	201761468	2	+	27260157	DLD1	viability	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.298711788248991	[]	[]	4	hSpCas9	negative selection	2620547
201760903	201760926	2	-	27260157	DLD1	viability	GTAAGAGAGGACTCAGAGCATGG	ALS2	ENSG00000003393	0.729029586900013	[]	[]	8	hSpCas9	negative selection	2640958
201761516	201761539	2	-	27260157	DLD1	viability	TTTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.819622345004712	[]	[]	-6	hSpCas9	negative selection	2641528
201757632	201757655	2	-	27260157	DLD1	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.400077374938698	[]	[]	4	hSpCas9	negative selection	2647048
201761215	201761238	2	-	27260157	HT1080	viability	GACAGTCATTGTTGCCCATTAGG	ALS2	ENSG00000003393	-0.317223120324775	[]	[]	-7	hSpCas9	negative selection	2650710
201767327	201767350	2	-	27260157	HT1080	viability	CTGGTCCATATCTGGCAGGCAGG	ALS2	ENSG00000003393	0.974621367239193	[]	[]	7	hSpCas9	negative selection	2653887
201761541	201761564	2	+	27260157	HT1080	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.221353937988136	[]	[]	0	hSpCas9	negative selection	2654366
201761591	201761614	2	+	27260157	HT1080	viability	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.408758761701359	[]	[]	-7	hSpCas9	negative selection	2655053
201761647	201761670	2	-	27260157	HT1080	viability	AATGGTGTCGCGTACATGTGGGG	ALS2	ENSG00000003393	-0.755193331691926	[]	[]	-8	hSpCas9	negative selection	2660287
201767241	201767264	2	+	27260157	HT1080	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.591619888879528	[]	[]	-7	hSpCas9	negative selection	2660337
201761368	201761391	2	-	27260157	HT1080	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	-0.236763688435981	[]	[]	0	hSpCas9	negative selection	2661830
201761766	201761789	2	+	27260157	HT1080	viability	CTCCACTGGTCCACTTCTCCAGG	ALS2	ENSG00000003393	0.499450245216867	[]	[]	4	hSpCas9	negative selection	2663392
201761415	201761438	2	+	27260157	HT1080	viability	TTGCGGCTTTGTCACTGGGAAGG	ALS2	ENSG00000003393	-1.08660818905253	[]	[]	-8	hSpCas9	negative selection	2663734
201768873	201768896	2	+	27260157	HT1080	viability	TCTTTGAGTCCATCGGTCAGTGG	ALS2	ENSG00000003393	-1.1177478294612	[]	[]	-8	hSpCas9	negative selection	2663781
201753180	201753203	2	-	27260157	HT1080	viability	GTAATCCATCTGGAGGCAGGTGG	ALS2	ENSG00000003393	-0.253370513538433	[]	[]	0	hSpCas9	negative selection	2680333
201746640	201746663	2	-	27260157	HT1080	viability	GTTATATTACAGTGGCCGACAGG	ALS2	ENSG00000003393	0.572323176097681	[]	[]	5	hSpCas9	negative selection	2681730
201768882	201768905	2	-	27260157	HT1080	viability	GGAGTGTTCCCACTGACCGATGG	ALS2	ENSG00000003393	-0.345301779579107	[]	[]	-7	hSpCas9	negative selection	2689055
201761609	201761632	2	+	27260157	HT1080	viability	GCTGGTTGGCTACTGCACACTGG	ALS2	ENSG00000003393	-0.591351828390556	[]	[]	-7	hSpCas9	negative selection	2689917
201757504	201757527	2	-	27260157	HT1080	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.0786740077424676	[]	[]	0	hSpCas9	negative selection	2692448
201761411	201761434	2	-	27260157	HT1080	viability	CCCAGTGACAAAGCCGCAAAAGG	ALS2	ENSG00000003393	0.0392281012689406	[]	[]	0	hSpCas9	negative selection	2696251
201761445	201761468	2	+	27260157	HT1080	viability	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	1.43518526936698	[]	[]	9	hSpCas9	negative selection	2696677
201760903	201760926	2	-	27260157	HT1080	viability	GTAAGAGAGGACTCAGAGCATGG	ALS2	ENSG00000003393	1.38374741529379	[]	[]	9	hSpCas9	negative selection	2717088
201761516	201761539	2	-	27260157	HT1080	viability	TTTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.92436958158403	[]	[]	7	hSpCas9	negative selection	2717658
201757632	201757655	2	-	27260157	HT1080	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.679466915633031	[]	[]	-8	hSpCas9	negative selection	2723178
201761215	201761238	2	-	27260157	MKN45	viability	GACAGTCATTGTTGCCCATTAGG	ALS2	ENSG00000003393	0.212775670817094	[]	[]	5	hSpCas9	negative selection	2726840
201767327	201767350	2	-	27260157	MKN45	viability	CTGGTCCATATCTGGCAGGCAGG	ALS2	ENSG00000003393	1.13331288883396	[]	[]	8	hSpCas9	negative selection	2730017
201761541	201761564	2	+	27260157	MKN45	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.509740631367415	[]	[]	6	hSpCas9	negative selection	2730496
201761591	201761614	2	+	27260157	MKN45	viability	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.600918530084577	[]	[]	-6	hSpCas9	negative selection	2731183
201761647	201761670	2	-	27260157	MKN45	viability	AATGGTGTCGCGTACATGTGGGG	ALS2	ENSG00000003393	-1.75588822804046	[]	[]	-9	hSpCas9	negative selection	2736417
201767241	201767264	2	+	27260157	MKN45	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.279175070939277	[]	[]	-1	hSpCas9	negative selection	2736467
201761368	201761391	2	-	27260157	MKN45	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.619379143134563	[]	[]	7	hSpCas9	negative selection	2737960
201761766	201761789	2	+	27260157	MKN45	viability	CTCCACTGGTCCACTTCTCCAGG	ALS2	ENSG00000003393	0.183088633458639	[]	[]	5	hSpCas9	negative selection	2739522
201761415	201761438	2	+	27260157	MKN45	viability	TTGCGGCTTTGTCACTGGGAAGG	ALS2	ENSG00000003393	-1.40573746858384	[]	[]	-8	hSpCas9	negative selection	2739864
201768873	201768896	2	+	27260157	MKN45	viability	TCTTTGAGTCCATCGGTCAGTGG	ALS2	ENSG00000003393	0.0615989596337052	[]	[]	0	hSpCas9	negative selection	2739911
201753180	201753203	2	-	27260157	MKN45	viability	GTAATCCATCTGGAGGCAGGTGG	ALS2	ENSG00000003393	0.0209785516309101	[]	[]	0	hSpCas9	negative selection	2756463
201746640	201746663	2	-	27260157	MKN45	viability	GTTATATTACAGTGGCCGACAGG	ALS2	ENSG00000003393	-0.0616273054892798	[]	[]	0	hSpCas9	negative selection	2757860
201768882	201768905	2	-	27260157	MKN45	viability	GGAGTGTTCCCACTGACCGATGG	ALS2	ENSG00000003393	-0.0567080472191916	[]	[]	0	hSpCas9	negative selection	2765185
201761609	201761632	2	+	27260157	MKN45	viability	GCTGGTTGGCTACTGCACACTGG	ALS2	ENSG00000003393	-0.218238444418805	[]	[]	-1	hSpCas9	negative selection	2766047
201757504	201757527	2	-	27260157	MKN45	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.497154684366068	[]	[]	6	hSpCas9	negative selection	2768578
201761411	201761434	2	-	27260157	MKN45	viability	CCCAGTGACAAAGCCGCAAAAGG	ALS2	ENSG00000003393	0.0133931070613322	[]	[]	0	hSpCas9	negative selection	2772381
201761445	201761468	2	+	27260157	MKN45	viability	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.991966554869204	[]	[]	8	hSpCas9	negative selection	2772807
201760903	201760926	2	-	27260157	MKN45	viability	GTAAGAGAGGACTCAGAGCATGG	ALS2	ENSG00000003393	0.721436213263394	[]	[]	7	hSpCas9	negative selection	2793218
201761516	201761539	2	-	27260157	MKN45	viability	TTTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.947960101199401	[]	[]	8	hSpCas9	negative selection	2793788
201757632	201757655	2	-	27260157	MKN45	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.415092392815059	[]	[]	-6	hSpCas9	negative selection	2799308
201761215	201761238	2	-	27260157	RKO	viability	GACAGTCATTGTTGCCCATTAGG	ALS2	ENSG00000003393	0.324540375873846	[]	[]	1	hSpCas9	negative selection	2802970
201767327	201767350	2	-	27260157	RKO	viability	CTGGTCCATATCTGGCAGGCAGG	ALS2	ENSG00000003393	0.610798752258245	[]	[]	3	hSpCas9	negative selection	2806147
201761541	201761564	2	+	27260157	RKO	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.152670334106483	[]	[]	0	hSpCas9	negative selection	2806626
201761591	201761614	2	+	27260157	RKO	viability	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.482994221648004	[]	[]	-6	hSpCas9	negative selection	2807313
201761647	201761670	2	-	27260157	RKO	viability	AATGGTGTCGCGTACATGTGGGG	ALS2	ENSG00000003393	-0.511742090544633	[]	[]	-6	hSpCas9	negative selection	2812547
201767241	201767264	2	+	27260157	RKO	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.603909494239987	[]	[]	3	hSpCas9	negative selection	2812597
201761368	201761391	2	-	27260157	RKO	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.555742584834383	[]	[]	3	hSpCas9	negative selection	2814090
201761766	201761789	2	+	27260157	RKO	viability	CTCCACTGGTCCACTTCTCCAGG	ALS2	ENSG00000003393	0.313452525090149	[]	[]	1	hSpCas9	negative selection	2815652
201761415	201761438	2	+	27260157	RKO	viability	TTGCGGCTTTGTCACTGGGAAGG	ALS2	ENSG00000003393	-0.366515941194815	[]	[]	-6	hSpCas9	negative selection	2815994
201768873	201768896	2	+	27260157	RKO	viability	TCTTTGAGTCCATCGGTCAGTGG	ALS2	ENSG00000003393	0.484316047355353	[]	[]	2	hSpCas9	negative selection	2816041
201753180	201753203	2	-	27260157	RKO	viability	GTAATCCATCTGGAGGCAGGTGG	ALS2	ENSG00000003393	0.195667399582679	[]	[]	1	hSpCas9	negative selection	2832593
201746640	201746663	2	-	27260157	RKO	viability	GTTATATTACAGTGGCCGACAGG	ALS2	ENSG00000003393	0.696566736289904	[]	[]	8	hSpCas9	negative selection	2833990
201768882	201768905	2	-	27260157	RKO	viability	GGAGTGTTCCCACTGACCGATGG	ALS2	ENSG00000003393	-0.128038240187249	[]	[]	0	hSpCas9	negative selection	2841315
201761609	201761632	2	+	27260157	RKO	viability	GCTGGTTGGCTACTGCACACTGG	ALS2	ENSG00000003393	-0.0239508135993514	[]	[]	0	hSpCas9	negative selection	2842177
201757504	201757527	2	-	27260157	RKO	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.355273091571461	[]	[]	2	hSpCas9	negative selection	2844708
201761411	201761434	2	-	27260157	RKO	viability	CCCAGTGACAAAGCCGCAAAAGG	ALS2	ENSG00000003393	0.0955561779622919	[]	[]	0	hSpCas9	negative selection	2848511
201761445	201761468	2	+	27260157	RKO	viability	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.651302663365669	[]	[]	3	hSpCas9	negative selection	2848937
201760903	201760926	2	-	27260157	RKO	viability	GTAAGAGAGGACTCAGAGCATGG	ALS2	ENSG00000003393	0.337865324766912	[]	[]	1	hSpCas9	negative selection	2869348
201761516	201761539	2	-	27260157	RKO	viability	TTTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.285376119837646	[]	[]	1	hSpCas9	negative selection	2869918
201757632	201757655	2	-	27260157	RKO	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.389239008814165	[]	[]	-6	hSpCas9	negative selection	2875438
201761215	201761238	2	-	27260157	SF268	viability	GACAGTCATTGTTGCCCATTAGG	ALS2	ENSG00000003393	-0.228150570275416	[]	[]	-2	hSpCas9	negative selection	2879100
201767327	201767350	2	-	27260157	SF268	viability	CTGGTCCATATCTGGCAGGCAGG	ALS2	ENSG00000003393	-0.425064126230403	[]	[]	-3	hSpCas9	negative selection	2882277
201761541	201761564	2	+	27260157	SF268	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.269641340373683	[]	[]	4	hSpCas9	negative selection	2882756
201761591	201761614	2	+	27260157	SF268	viability	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.0100796170840912	[]	[]	0	hSpCas9	negative selection	2883443
201761647	201761670	2	-	27260157	SF268	viability	AATGGTGTCGCGTACATGTGGGG	ALS2	ENSG00000003393	-0.40742065772847	[]	[]	-3	hSpCas9	negative selection	2888677
201767241	201767264	2	+	27260157	SF268	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.50455374157111	[]	[]	7	hSpCas9	negative selection	2888727
201761368	201761391	2	-	27260157	SF268	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	-0.696320084995827	[]	[]	-5	hSpCas9	negative selection	2890220
201761766	201761789	2	+	27260157	SF268	viability	CTCCACTGGTCCACTTCTCCAGG	ALS2	ENSG00000003393	0.317667831889961	[]	[]	4	hSpCas9	negative selection	2891782
201761415	201761438	2	+	27260157	SF268	viability	TTGCGGCTTTGTCACTGGGAAGG	ALS2	ENSG00000003393	-0.823619033542506	[]	[]	-6	hSpCas9	negative selection	2892124
201768873	201768896	2	+	27260157	SF268	viability	TCTTTGAGTCCATCGGTCAGTGG	ALS2	ENSG00000003393	0.236890242598255	[]	[]	3	hSpCas9	negative selection	2892171
201753180	201753203	2	-	27260157	SF268	viability	GTAATCCATCTGGAGGCAGGTGG	ALS2	ENSG00000003393	-0.542296761419105	[]	[]	-4	hSpCas9	negative selection	2908723
201746640	201746663	2	-	27260157	SF268	viability	GTTATATTACAGTGGCCGACAGG	ALS2	ENSG00000003393	0.442248991525279	[]	[]	7	hSpCas9	negative selection	2910120
201768882	201768905	2	-	27260157	SF268	viability	GGAGTGTTCCCACTGACCGATGG	ALS2	ENSG00000003393	-0.00695469267439653	[]	[]	0	hSpCas9	negative selection	2917445
201761609	201761632	2	+	27260157	SF268	viability	GCTGGTTGGCTACTGCACACTGG	ALS2	ENSG00000003393	-0.304708836387545	[]	[]	-2	hSpCas9	negative selection	2918307
201757504	201757527	2	-	27260157	SF268	viability	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.420354488563372	[]	[]	4	hSpCas9	negative selection	2920838
201761411	201761434	2	-	27260157	SF268	viability	CCCAGTGACAAAGCCGCAAAAGG	ALS2	ENSG00000003393	0.580844968167508	[]	[]	8	hSpCas9	negative selection	2924641
201761445	201761468	2	+	27260157	SF268	viability	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.279135033860053	[]	[]	4	hSpCas9	negative selection	2925067
201760903	201760926	2	-	27260157	SF268	viability	GTAAGAGAGGACTCAGAGCATGG	ALS2	ENSG00000003393	0.499539981035249	[]	[]	7	hSpCas9	negative selection	2945478
201761516	201761539	2	-	27260157	SF268	viability	TTTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.292651658647053	[]	[]	-2	hSpCas9	negative selection	2946048
201757632	201757655	2	-	27260157	SF268	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.153045989941829	[]	[]	-1	hSpCas9	negative selection	2951568
201761713	201761736	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.36372696904125895	[5,5]	[4,6]	7	hSpCas9	positive selection	2970017
201767294	201767317	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	0.26021126467601974	[6,6]	[5,7]	5	hSpCas9	positive selection	2970018
201767246	201767269	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	-0.042082244130553004	[4,4]	[4,3]	0	hSpCas9	positive selection	2970019
201761768	201761791	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	0.0447330777624535	[4,4]	[5,3]	0	hSpCas9	positive selection	2970020
201761713	201761736	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.04967344820455255	[5,5]	[4,2]	0	hSpCas9	positive selection	3037875
201767294	201767317	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	0.24748442477215593	[6,6]	[6,4]	4	hSpCas9	positive selection	3037876
201767246	201767269	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	-0.044284375981604285	[4,4]	[4,1]	0	hSpCas9	positive selection	3037877
201761768	201761791	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	0.22345843391718245	[4,4]	[4,3]	4	hSpCas9	positive selection	3037878
201761453	201761476		-	24336571	A375	resistance to PLX after 7 days	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	0.02451225584470188	[10,13]	[9,14]	0	hSpCas9	positive selection	3115025
201767241	201767264		+	24336571	A375	resistance to PLX after 7 days	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.035184025246684014	[15,16]	[15,16]	1	hSpCas9	positive selection	3115037
201767268	201767291		-	24336571	A375	resistance to PLX after 7 days	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	-0.011082646657151418	[19,20]	[19,19]	0	hSpCas9	positive selection	3115048
201757632	201757655		-	24336571	A375	resistance to PLX after 7 days	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.276841890518817	[3,4]	[4,4]	7	hSpCas9	positive selection	3115059
201757694	201757717		+	24336571	A375	resistance to PLX after 7 days	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	0.04338983154166015	[9,8]	[11,7]	1	hSpCas9	positive selection	3115070
201757398	201757421		+	24336571	A375	resistance to PLX after 7 days	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	0.17474141986974606	[9,9]	[10,11]	5	hSpCas9	positive selection	3115081
201761591	201761614		+	24336571	A375	resistance to PLX after 7 days	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.38128578755441744	[17,12]	[11,10]	-9	hSpCas9	positive selection	3115092
201761453	201761476		-	24336571	A375	resistance to PLX after 14 days	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	-1.076734877545799	[24,19]	[5,2]	-9	hSpCas9	positive selection	3172818
201767241	201767264		+	24336571	A375	resistance to PLX after 14 days	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.5617614194770398	[12,16]	[5,2]	-6	hSpCas9	positive selection	3172830
201767268	201767291		-	24336571	A375	resistance to PLX after 14 days	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	0.07610857242319535	[17,17]	[8,7]	0	hSpCas9	positive selection	3172841
201757632	201757655		-	24336571	A375	resistance to PLX after 14 days	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.09742416065089954	[4,7]	[2,2]	1	hSpCas9	positive selection	3172852
201757694	201757717		+	24336571	A375	resistance to PLX after 14 days	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	-0.5559333619278096	[18,8]	[3,3]	-6	hSpCas9	positive selection	3172863
201757398	201757421		+	24336571	A375	resistance to PLX after 14 days	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	-0.677672428928645	[10,13]	[2,3]	-7	hSpCas9	positive selection	3172874
201761591	201761614		+	24336571	A375	resistance to PLX after 14 days	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.5258904784109898	[12,10]	[2,3]	-6	hSpCas9	positive selection	3172885
201761453	201761476		-	24336571	A375	viability after 7 days	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	0.42981026071315226	[9]	[10,13]	6	hSpCas9	negative selection	3230611
201767241	201767264		+	24336571	A375	viability after 7 days	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.4716357385392692	[23]	[15,16]	-6	hSpCas9	negative selection	3230623
201767268	201767291		-	24336571	A375	viability after 7 days	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	0.02517420225261069	[20]	[19,20]	0	hSpCas9	negative selection	3230634
201757632	201757655		-	24336571	A375	viability after 7 days	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.018860540208982313	[4]	[3,4]	0	hSpCas9	negative selection	3230645
201757694	201757717		+	24336571	A375	viability after 7 days	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	0.4410592452043956	[6]	[9,8]	6	hSpCas9	negative selection	3230656
201757398	201757421		+	24336571	A375	viability after 7 days	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	-0.27606093898616757	[12]	[9,9]	-4	hSpCas9	negative selection	3230667
201761591	201761614		+	24336571	A375	viability after 7 days	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	0.16603184744681732	[13]	[17,12]	2	hSpCas9	negative selection	3230678
201761453	201761476		-	24336571	A375	viability after 14 days	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	1.243609862507612	[9]	[24,19]	9	hSpCas9	negative selection	3288404
201767241	201767264		+	24336571	A375	viability after 14 days	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.6053381799768269	[23]	[12,16]	-6	hSpCas9	negative selection	3288416
201767268	201767291		-	24336571	A375	viability after 14 days	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	-0.1379287255777749	[20]	[17,17]	-1	hSpCas9	negative selection	3288427
201757632	201757655		-	24336571	A375	viability after 14 days	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.5837033029187202	[4]	[4,7]	7	hSpCas9	negative selection	3288438
201757694	201757717		+	24336571	A375	viability after 14 days	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	0.9644336020277341	[6]	[18,8]	9	hSpCas9	negative selection	3288449
201757398	201757421		+	24336571	A375	viability after 14 days	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	0.046755760988686695	[12]	[10,13]	0	hSpCas9	negative selection	3288460
201761591	201761614		+	24336571	A375	viability after 14 days	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	-0.1192753238983858	[13]	[12,10]	-1	hSpCas9	negative selection	3288471
201767241	201767264	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.3458879938315436	[185,202]	[0,0]	-2	hSpCas9	positive selection	3336374
201754502	201754525	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.45929714132288196	[186,233]	[0,0]	-3	hSpCas9	positive selection	3336375
201757632	201757655	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.35665668430348674	[116,121]	[0,0]	1	hSpCas9	positive selection	3336376
201767328	201767351	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-1.3901322150090851	[400,400]	[0,0]	-8	hSpCas9	positive selection	3355630
201757669	201757692	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.4244361972810935	[113,113]	[0,0]	2	hSpCas9	positive selection	3355631
201754648	201754671	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3355632
201761712	201761735	2	+	26780180	HT29	viability (Avana library 4 designs)	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.373173635133541	[]	[]	1	hSpCas9	negative selection	3406101
201767294	201767317	2	-	26780180	HT29	viability (Avana library 4 designs)	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	0.115046416632117	[]	[]	0	hSpCas9	negative selection	3406102
201767246	201767269	2	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	0.193452365916927	[]	[]	0	hSpCas9	negative selection	3406103
201761767	201761790	2	+	26780180	HT29	viability (Avana library 4 designs)	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	0.325364846294	[]	[]	1	hSpCas9	negative selection	3406104
201761712	201761735	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-5.526479570619	[]	[]	-6	hSpCas9	negative selection	3478443
201761767	201761790	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	2.33543062011172	[]	[]	3	hSpCas9	negative selection	3478444
201767294	201767317	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	2.17894763139702	[]	[]	3	hSpCas9	negative selection	3478445
201767246	201767269	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	4.1920934733806	[]	[]	7	hSpCas9	negative selection	3478446
201761445	201761468	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-5.58647267965113	[]	[]	-6	hSpCas9	negative selection	3478447
201761665	201761688	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGGAGCAGTGACAGACAATGG	ALS2	ENSG00000003393	2.83169787825686	[]	[]	4	hSpCas9	negative selection	3478448
201761712	201761735	2	+	26780180	A375	viability (Avana lentiGuide)	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-1.95244917171615	[]	[]	-3	hSpCas9	negative selection	3587102
201761767	201761790	2	+	26780180	A375	viability (Avana lentiGuide)	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	-3.06450739180736	[]	[]	-5	hSpCas9	negative selection	3587103
201767294	201767317	2	-	26780180	A375	viability (Avana lentiGuide)	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	-1.05198238005738	[]	[]	-2	hSpCas9	negative selection	3587104
201767246	201767269	2	-	26780180	A375	viability (Avana lentiGuide)	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	-1.78489969157022	[]	[]	-3	hSpCas9	negative selection	3587105
201761445	201761468	2	+	26780180	A375	viability (Avana lentiGuide)	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.681112135555018	[]	[]	-1	hSpCas9	negative selection	3587106
201761665	201761688	2	-	26780180	A375	viability (Avana lentiGuide)	AGTGGAGCAGTGACAGACAATGG	ALS2	ENSG00000003393	-2.33995343248395	[]	[]	-4	hSpCas9	negative selection	3587107
201761712	201761735	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.2821939618777703	[7]	[5,5]	-4	hSpCas9	positive selection	3695761
201761767	201761790	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	0.10856066247975671	[6]	[6,6]	3	hSpCas9	positive selection	3695762
201767294	201767317	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	-0.03089060760906026	[6]	[6,5]	0	hSpCas9	positive selection	3695763
201767246	201767269	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	0.3746077894125308	[4]	[5,6]	9	hSpCas9	positive selection	3695764
201761445	201761468	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.1853872769229422	[6]	[5,4]	-3	hSpCas9	positive selection	3695765
201761665	201761688	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGGAGCAGTGACAGACAATGG	ALS2	ENSG00000003393	0.03206377761518782	[4]	[5,4]	0	hSpCas9	positive selection	3695766
201761712	201761735	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.24473582479067785	[6]	[6,6]	6	hSpCas9	positive selection	3804368
201761767	201761790	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCACTGGTCCACTTCTCCAGGG	ALS2	ENSG00000003393	-0.11745822110581078	[6]	[5,3]	-2	hSpCas9	positive selection	3804369
201767294	201767317	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAACACCAGAGAGATTGCCAGG	ALS2	ENSG00000003393	0.27425602966771706	[7]	[8,7]	7	hSpCas9	positive selection	3804370
201767246	201767269	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCCTCGGAGTGAAACATGG	ALS2	ENSG00000003393	0.2223918516260311	[5]	[5,6]	5	hSpCas9	positive selection	3804371
201761445	201761468	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.2698876528430473	[7]	[7,7]	7	hSpCas9	positive selection	3804372
201761665	201761688	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGGAGCAGTGACAGACAATGG	ALS2	ENSG00000003393	0.050420494238882396	[5]	[3,5]	1	hSpCas9	positive selection	3804373
201757669	201757692	2	+	26780180	A375	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	2.10878993383191	[]	[]	9	hSpCas9	negative selection	3912779
201767328	201767351	2	+	26780180	A375	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.8738055285461	[]	[]	3	hSpCas9	negative selection	3912780
201767241	201767264	2	+	26780180	A375	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.255395310776333	[]	[]	0	hSpCas9	negative selection	3912781
201754502	201754525	2	-	26780180	A375	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	1.1909805520561	[]	[]	6	hSpCas9	negative selection	3912782
201757632	201757655	2	-	26780180	A375	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	1.29348512663608	[]	[]	7	hSpCas9	negative selection	3912783
201754648	201754671	2	-	26780180	A375	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.604921418996505	[]	[]	2	hSpCas9	negative selection	3912784
201757669	201757692	2	+	26780180	HT29	viability (GeCKOv2 library)	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	1.76905897947762	[]	[]	8	hSpCas9	negative selection	4020745
201767328	201767351	2	+	26780180	HT29	viability (GeCKOv2 library)	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	1.27404196097013	[]	[]	6	hSpCas9	negative selection	4020746
201767241	201767264	2	+	26780180	HT29	viability (GeCKOv2 library)	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	1.22014777881969	[]	[]	6	hSpCas9	negative selection	4020747
201754502	201754525	2	-	26780180	HT29	viability (GeCKOv2 library)	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.882907880973674	[]	[]	4	hSpCas9	negative selection	4020748
201757632	201757655	2	-	26780180	HT29	viability (GeCKOv2 library)	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	1.17647469676254	[]	[]	6	hSpCas9	negative selection	4020749
201754648	201754671	2	-	26780180	HT29	viability (GeCKOv2 library)	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.970323267596316	[]	[]	4	hSpCas9	negative selection	4020750
201761453	201761476	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	0.10123882941901209	[3]	[3,1]	2	hSpCas9	positive selection	4138095
201767241	201767264	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.18196139582929177	[4]	[2,1]	-4	hSpCas9	positive selection	4138107
201767268	201767291	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	0.04423757195746267	[4]	[2,3]	1	hSpCas9	positive selection	4138118
201757632	201757655	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.07988442199829582	[2]	[1,1]	2	hSpCas9	positive selection	4138129
201757694	201757717	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	0.026606618478292432	[3]	[2,1]	0	hSpCas9	positive selection	4138140
201757398	201757421	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	-0.10041466296424398	[3]	[1,1]	-2	hSpCas9	positive selection	4138151
201761591	201761614	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	0.3571743989637502	[3]	[4,1]	8	hSpCas9	positive selection	4138162
201761453	201761476	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGGGGTACCGGTTGTCAGTTGG	ALS2	ENSG00000003393	1.7131790635446067	[2]	[3,3,4,4]	9	hSpCas9	positive selection	4202117
201767241	201767264	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.5013541177173702	[4]	[4,2,4,0]	3	hSpCas9	positive selection	4202129
201767268	201767291	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGAGGAAAGACTGTTTTGCAGG	ALS2	ENSG00000003393	1.0946421244633975	[3]	[3,3,0,3]	8	hSpCas9	positive selection	4202140
201757632	201757655	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.09989994741185759	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4202151
201757694	201757717	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTTAGGGCTGAGGTGCTTGTGG	ALS2	ENSG00000003393	1.6729087310150974	[1]	[0,1,0,3]	9	hSpCas9	positive selection	4202162
201757398	201757421	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACCTTGTGACAACAATCCAGG	ALS2	ENSG00000003393	-0.4545470025829343	[4]	[2,0,0,0]	-6	hSpCas9	positive selection	4202173
201761591	201761614	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGGTTCCGGCACATACTGCTGG	ALS2	ENSG00000003393	0.7193960300067697	[4]	[1,3,1,3]	4	hSpCas9	positive selection	4202184
201767241	201767264	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.08288529758534971	[3]	[3,1]	-2	hSpCas9	positive selection	4255421
201754502	201754525	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.6528991131941073	[3]	[4,5]	9	hSpCas9	positive selection	4255422
201757632	201757655	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.4839137144124535	[2]	[2,0]	-8	hSpCas9	positive selection	4255423
201767328	201767351	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.010881148101693938	[3]	[3,1]	0	hSpCas9	positive selection	4319703
201757669	201757692	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.38838889514233077	[3]	[3,0]	-7	hSpCas9	positive selection	4319704
201754648	201754671	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.3933968292095827	[2]	[3,1]	7	hSpCas9	positive selection	4319705
201761446	201761468	2	+	27760321	OCIAML3	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.9018846281985049	[343,336]	[480,521]	9	hSpCas9	negative selection	4377552
201761516	201761538	2	-	27760321	OCIAML3	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.10698012908692389	[1183,1028]	[735,886]	-1	hSpCas9	negative selection	4377553
201761649	201761671	2	-	27760321	OCIAML3	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.9107390161037632	[551,404]	[158,246]	-7	hSpCas9	negative selection	4377554
201761670	201761692	2	+	27760321	OCIAML3	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	-0.23738701146306995	[692,644]	[433,456]	-3	hSpCas9	negative selection	4377555
201761713	201761735	2	+	27760321	OCIAML3	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.549004966793226	[172,137]	[66,102]	-5	hSpCas9	negative selection	4377556
201761446	201761468	2	+	27760321	OCIAML2	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.7398009138749244	[343,336]	[423,509]	8	hSpCas9	negative selection	4461015
201761516	201761538	2	-	27760321	OCIAML2	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.06229023755981489	[1183,1028]	[745,998]	-1	hSpCas9	negative selection	4461016
201761649	201761671	2	-	27760321	OCIAML2	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.09251540681906953	[551,404]	[325,403]	-1	hSpCas9	negative selection	4461017
201761670	201761692	2	+	27760321	OCIAML2	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.4524771922742309	[692,644]	[600,924]	6	hSpCas9	negative selection	4461018
201761713	201761735	2	+	27760321	OCIAML2	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.26785598284459056	[172,137]	[131,174]	3	hSpCas9	negative selection	4461019
201761446	201761468	2	+	27760321	MV411	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.2340303390606841	[343,336]	[160,420]	1	hSpCas9	negative selection	4544478
201761516	201761538	2	-	27760321	MV411	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.5113101303336751	[1183,1028]	[1028,1051]	3	hSpCas9	negative selection	4544479
201761649	201761671	2	-	27760321	MV411	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.5830924823385644	[551,404]	[227,179]	-4	hSpCas9	negative selection	4544480
201761670	201761692	2	+	27760321	MV411	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	1.1437675912437864	[692,644]	[1215,614]	8	hSpCas9	negative selection	4544481
201761713	201761735	2	+	27760321	MV411	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.6549387649540557	[172,137]	[43,95]	-4	hSpCas9	negative selection	4544482
201761446	201761468	2	+	27760321	HL60	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.6479941608928126	[343,336]	[208,144]	-6	hSpCas9	negative selection	4627941
201761516	201761538	2	-	27760321	HL60	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.24047543756902634	[1183,1028]	[819,702]	-3	hSpCas9	negative selection	4627942
201761649	201761671	2	-	27760321	HL60	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.051464020307565764	[551,404]	[494,244]	0	hSpCas9	negative selection	4627943
201761670	201761692	2	+	27760321	HL60	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.6011145744403369	[692,644]	[853,802]	7	hSpCas9	negative selection	4627944
201761713	201761735	2	+	27760321	HL60	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.10668389884053275	[172,137]	[92,142]	-1	hSpCas9	negative selection	4627945
201761446	201761468	2	+	27760321	HT1080	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.46326218084194304	[336,262]	[58,116]	-2	hSpCas9	negative selection	4711404
201761516	201761538	2	-	27760321	HT1080	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.8193926139200505	[1028,802]	[768,506]	4	hSpCas9	negative selection	4711405
201761649	201761671	2	-	27760321	HT1080	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.815282287062861	[404,315]	[83,78]	-3	hSpCas9	negative selection	4711406
201761670	201761692	2	+	27760321	HT1080	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.4131411658155588	[644,503]	[436,159]	2	hSpCas9	negative selection	4711407
201761713	201761735	2	+	27760321	HT1080	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-3.0854916104149934	[137,107]	[0,10]	-7	hSpCas9	negative selection	4711408
201761446	201761468	2	+	27760321	HT29	viability after 7 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.03628827501302356	[336,262]	[626,267,271]	0	hSpCas9	negative selection	4794867
201761516	201761538	2	-	27760321	HT29	viability after 7 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.15308845976691	[1028,802]	[1157,1100,934]	-2	hSpCas9	negative selection	4794868
201761649	201761671	2	-	27760321	HT29	viability after 7 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.0034050532731355705	[404,315]	[352,684,336]	0	hSpCas9	negative selection	4794869
201761670	201761692	2	+	27760321	HT29	viability after 7 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.10646101235372818	[644,503]	[756,629,985]	1	hSpCas9	negative selection	4794870
201761713	201761735	2	+	27760321	HT29	viability after 7 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.5217673667894032	[137,107]	[312,210,170]	7	hSpCas9	negative selection	4794871
201761446	201761468	2	+	27760321	HT29	viability after 25 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.27146986705267023	[336,262]	[397,445,395]	3	hSpCas9	negative selection	4878330
201761516	201761538	2	-	27760321	HT29	viability after 25 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.3429369841263368	[1028,802]	[842,1639,1551]	3	hSpCas9	negative selection	4878331
201761649	201761671	2	-	27760321	HT29	viability after 25 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	0.19538918557536628	[404,315]	[430,350,653]	2	hSpCas9	negative selection	4878332
201761670	201761692	2	+	27760321	HT29	viability after 25 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	-0.10789727817555184	[644,503]	[512,546,791]	-1	hSpCas9	negative selection	4878333
201761713	201761735	2	+	27760321	HT29	viability after 25 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.6902796184315168	[137,107]	[91,220,392]	7	hSpCas9	negative selection	4878334
201761446	201761468	2	+	27760321	HT29	viability after 22 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.3145814898995329	[336,262]	[481,541,266]	3	hSpCas9	negative selection	4961793
201761516	201761538	2	-	27760321	HT29	viability after 22 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.06915716484413847	[1028,802]	[1078,1102,1151]	0	hSpCas9	negative selection	4961794
201761649	201761671	2	-	27760321	HT29	viability after 22 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.04700236829843478	[404,315]	[500,356,348]	0	hSpCas9	negative selection	4961795
201761670	201761692	2	+	27760321	HT29	viability after 22 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.24083189253817439	[644,503]	[758,734,861]	2	hSpCas9	negative selection	4961796
201761713	201761735	2	+	27760321	HT29	viability after 22 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	1.2313139226537948	[137,107]	[272,326,403]	9	hSpCas9	negative selection	4961797
201761446	201761468	2	+	27760321	HT29	viability after 19 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.4973875680169214	[336,262]	[623,430,414]	5	hSpCas9	negative selection	5045256
201761516	201761538	2	-	27760321	HT29	viability after 19 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.41269045442503605	[1028,802]	[1038,1914,1198]	4	hSpCas9	negative selection	5045257
201761649	201761671	2	-	27760321	HT29	viability after 19 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.306802044462366	[404,315]	[370,576,65]	-3	hSpCas9	negative selection	5045258
201761670	201761692	2	+	27760321	HT29	viability after 19 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.355486902550177	[644,503]	[858,865,799]	3	hSpCas9	negative selection	5045259
201761713	201761735	2	+	27760321	HT29	viability after 19 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.2573683783202616	[137,107]	[197,287,26]	2	hSpCas9	negative selection	5045260
201761446	201761468	2	+	27760321	HT29	viability after 16 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.39157493139978244	[336,262]	[692,428,222]	4	hSpCas9	negative selection	5128719
201761516	201761538	2	-	27760321	HT29	viability after 16 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.170167175897751	[1028,802]	[1101,1088,1264]	1	hSpCas9	negative selection	5128720
201761649	201761671	2	-	27760321	HT29	viability after 16 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	-0.15873877651143536	[404,315]	[367,455,257]	-2	hSpCas9	negative selection	5128721
201761670	201761692	2	+	27760321	HT29	viability after 16 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.4858209096207702	[644,503]	[920,835,946]	5	hSpCas9	negative selection	5128722
201761713	201761735	2	+	27760321	HT29	viability after 16 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	0.8811908690743243	[137,107]	[153,371,221]	9	hSpCas9	negative selection	5128723
201761446	201761468	2	+	27760321	HT29	viability after 13 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.5708148045113302	[336,262]	[842,513,211]	7	hSpCas9	negative selection	5212182
201761516	201761538	2	-	27760321	HT29	viability after 13 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	-0.1873384497800883	[1028,802]	[703,1058,1030]	-2	hSpCas9	negative selection	5212183
201761649	201761671	2	-	27760321	HT29	viability after 13 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	0.05926660814677651	[404,315]	[288,539,475]	0	hSpCas9	negative selection	5212184
201761670	201761692	2	+	27760321	HT29	viability after 13 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.1412325344145916	[644,503]	[878,713,618]	1	hSpCas9	negative selection	5212185
201761713	201761735	2	+	27760321	HT29	viability after 13 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.021446321841124494	[137,107]	[57,69,284]	0	hSpCas9	negative selection	5212186
201761446	201761468	2	+	27760321	HT29	viability after 10 days	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	-0.017220710773990733	[336,262]	[470,338,300]	0	hSpCas9	negative selection	5295645
201761516	201761538	2	-	27760321	HT29	viability after 10 days	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.10367743438375343	[1028,802]	[1334,1372,987]	1	hSpCas9	negative selection	5295646
201761649	201761671	2	-	27760321	HT29	viability after 10 days	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	0.3111997407493863	[404,315]	[520,609,545]	4	hSpCas9	negative selection	5295647
201761670	201761692	2	+	27760321	HT29	viability after 10 days	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.24382175404279194	[644,503]	[640,1079,833]	3	hSpCas9	negative selection	5295648
201761713	201761735	2	+	27760321	HT29	viability after 10 days	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-0.10154355063974907	[137,107]	[84,119,221]	-1	hSpCas9	negative selection	5295649
201761446	201761468	2	+	27760321	MOLM13	viability	ATGAGACCCAACTGACAACCGG	ALS2	ENSG00000003393	0.614444336452531	[343,336]	[397,206]	4	hSpCas9	negative selection	5379108
201761516	201761538	2	-	27760321	MOLM13	viability	TTACAGTTGGCGTGTGGCGAGG	ALS2	ENSG00000003393	0.03834565534760204	[1183,1028]	[450,799]	0	hSpCas9	negative selection	5379109
201761649	201761671	2	-	27760321	MOLM13	viability	CAATGGTGTCGCGTACATGTGG	ALS2	ENSG00000003393	0.5892822927330846	[551,404]	[208,566]	4	hSpCas9	negative selection	5379110
201761670	201761692	2	+	27760321	MOLM13	viability	GTCTGTCACTGCTCCACTATGG	ALS2	ENSG00000003393	0.3264024118006127	[692,644]	[628,340]	2	hSpCas9	negative selection	5379111
201761713	201761735	2	+	27760321	MOLM13	viability	ATAACATATTGCCCAACCAGGG	ALS2	ENSG00000003393	-1.315978479850314	[172,137]	[74,0]	-6	hSpCas9	negative selection	5379112
201780524	201780547	2	+	27661255	K562	viability	GAATAGCTGGAAGGCAGCGTGGG	ALS2	ENSG00000003393	0.27315129348419165	[1036,1363]	[1265,1056]	8	dCas9-KRAB	negative selection	5461927
201767241	201767264	2	+	27260156	BXPC3	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.0794391945706802	[528]	[455,462,575,618]	-2	hSpCas9	negative selection	5527881
201754502	201754525	2	-	27260156	BXPC3	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.19530985677223056	[769]	[901,817,985,992]	4	hSpCas9	negative selection	5527882
201757632	201757655	2	-	27260156	BXPC3	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.2956712254888214	[383]	[281,331,291,414]	-6	hSpCas9	negative selection	5527883
201767328	201767351	2	+	27260156	BXPC3	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.3202878425350666	[781]	[850,880,1086,1322]	7	hSpCas9	negative selection	5592163
201757669	201757692	2	+	27260156	BXPC3	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.16984727990327486	[531]	[393,536,483,577]	-4	hSpCas9	negative selection	5592164
201754648	201754671	2	-	27260156	BXPC3	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.2993604188572676	[231]	[222,274,320,394]	6	hSpCas9	negative selection	5592165
201767241	201767264	2	+	27260156	A673	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.0921337225012939	[528]	[722,545,707,741]	2	hSpCas9	negative selection	5649132
201754502	201754525	2	-	27260156	A673	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.15481742794998166	[769]	[976,917,667,769]	-4	hSpCas9	negative selection	5649133
201757632	201757655	2	-	27260156	A673	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.11708170448787236	[383]	[425,326,471,479]	-3	hSpCas9	negative selection	5649134
201767328	201767351	2	+	27260156	A673	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.14027059814469456	[781]	[1113,985,982,1066]	3	hSpCas9	negative selection	5713414
201757669	201757692	2	+	27260156	A673	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.40489907792678975	[531]	[559,466,410,501]	-7	hSpCas9	negative selection	5713415
201754648	201754671	2	-	27260156	A673	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.24708988185081304	[231]	[392,332,249,354]	6	hSpCas9	negative selection	5713416
201767241	201767264	2	+	27260156	A375	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.047551636047913515	[528]	[620,542,586,626]	0	hSpCas9	negative selection	5770383
201754502	201754525	2	-	27260156	A375	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.04931632633559058	[769]	[1026,1008,1165,571]	0	hSpCas9	negative selection	5770384
201757632	201757655	2	-	27260156	A375	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.35214304951358577	[383]	[224,413,440,333]	-5	hSpCas9	negative selection	5770385
201767328	201767351	2	+	27260156	A375	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.11881377986677577	[781]	[826,1249,1086,850]	1	hSpCas9	negative selection	5834665
201757669	201757692	2	+	27260156	A375	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.06904043975714375	[531]	[731,734,775,403]	1	hSpCas9	negative selection	5834666
201754648	201754671	2	-	27260156	A375	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.6234487294913916	[231]	[520,344,422,374]	8	hSpCas9	negative selection	5834667
201767241	201767264	2	+	27260156	COLO741	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.06989451628729745	[528]	[922,672,559]	1	hSpCas9	negative selection	5891634
201754502	201754525	2	-	27260156	COLO741	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.023161980113504343	[769]	[1044,1014,944]	0	hSpCas9	negative selection	5891635
201757632	201757655	2	-	27260156	COLO741	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.07745186554196598	[383]	[537,466,399]	-2	hSpCas9	negative selection	5891636
201767328	201767351	2	+	27260156	COLO741	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.10227511958918156	[781]	[909,1162,730]	-2	hSpCas9	negative selection	5955916
201757669	201757692	2	+	27260156	COLO741	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.4320065945816426	[531]	[519,407,577]	-7	hSpCas9	negative selection	5955917
201754648	201754671	2	-	27260156	COLO741	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.4291242834583373	[231]	[372,445,376]	8	hSpCas9	negative selection	5955918
201767241	201767264	2	+	27260156	CAL120	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.0636561302665627	[528]	[852,576,658]	0	hSpCas9	negative selection	6012885
201754502	201754525	2	-	27260156	CAL120	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.1258110196696015	[769]	[1156,748,771]	-2	hSpCas9	negative selection	6012886
201757632	201757655	2	-	27260156	CAL120	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.4125619665400214	[383]	[179,291,573]	-5	hSpCas9	negative selection	6012887
201767328	201767351	2	+	27260156	CAL120	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.11898246854292394	[781]	[1024,771,909]	-2	hSpCas9	negative selection	6077167
201757669	201757692	2	+	27260156	CAL120	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.016724474280056217	[531]	[606,583,805]	0	hSpCas9	negative selection	6077168
201754648	201754671	2	-	27260156	CAL120	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.05232902132242623	[231]	[323,240,335]	0	hSpCas9	negative selection	6077169
201767241	201767264	2	+	27260156	CADOES1	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.0605168457415623	[528]	[538,394,476,645]	1	hSpCas9	negative selection	6134136
201754502	201754525	2	-	27260156	CADOES1	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.1717728548798556	[769]	[659,584,683,612]	-3	hSpCas9	negative selection	6134137
201757632	201757655	2	-	27260156	CADOES1	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.18634194898625478	[383]	[326,158,329,443]	-3	hSpCas9	negative selection	6134138
201767328	201767351	2	+	27260156	CADOES1	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.37325345939392607	[781]	[1083,668,1180,828]	6	hSpCas9	negative selection	6198418
201757669	201757692	2	+	27260156	CADOES1	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.11633863020577728	[531]	[529,497,385,409]	-2	hSpCas9	negative selection	6198419
201754648	201754671	2	-	27260156	CADOES1	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.45150798637374057	[231]	[197,342,384,252]	7	hSpCas9	negative selection	6198420
201767241	201767264	2	+	27260156	EWS502	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.04895071599505543	[528]	[526,570,487,580]	-1	hSpCas9	negative selection	6255387
201754502	201754525	2	-	27260156	EWS502	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.17829156242035415	[769]	[817,581,649,830]	-3	hSpCas9	negative selection	6255388
201757632	201757655	2	-	27260156	EWS502	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.47485587056366985	[383]	[238,311,311,313]	-7	hSpCas9	negative selection	6255389
201767328	201767351	2	+	27260156	EWS502	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.0025433764825372185	[781]	[831,884,885,688]	0	hSpCas9	negative selection	6319669
201757669	201757692	2	+	27260156	EWS502	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.19562858647157816	[531]	[548,502,473,427]	-3	hSpCas9	negative selection	6319670
201754648	201754671	2	-	27260156	EWS502	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.5280986258086313	[231]	[177,364,342,565]	8	hSpCas9	negative selection	6319671
201767241	201767264	2	+	27260156	EW8	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.05253629001377294	[528]	[440,457,309,463]	-1	hSpCas9	negative selection	6376638
201754502	201754525	2	-	27260156	EW8	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.31578727675884527	[769]	[635,413,413,568]	-5	hSpCas9	negative selection	6376639
201757632	201757655	2	-	27260156	EW8	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.24091780199597923	[383]	[301,326,271,154]	-4	hSpCas9	negative selection	6376640
201767328	201767351	2	+	27260156	EW8	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.1767106783318252	[781]	[953,639,634,673]	3	hSpCas9	negative selection	6440920
201757669	201757692	2	+	27260156	EW8	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.31467000798016864	[531]	[435,351,326,283]	-5	hSpCas9	negative selection	6440921
201754648	201754671	2	-	27260156	EW8	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.3592379608253472	[231]	[284,264,223,197]	6	hSpCas9	negative selection	6440922
201767241	201767264	2	+	27260156	CORL105	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.2680467672593315	[528]	[749,649,774,813]	5	hSpCas9	negative selection	6497889
201754502	201754525	2	-	27260156	CORL105	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.0037173052314699584	[769]	[931,828,997,872]	0	hSpCas9	negative selection	6497890
201757632	201757655	2	-	27260156	CORL105	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.21162011024316096	[383]	[501,227,440,396]	-4	hSpCas9	negative selection	6497891
201767328	201767351	2	+	27260156	CORL105	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.14161650352951471	[781]	[996,961,1156,946]	2	hSpCas9	negative selection	6562171
201757669	201757692	2	+	27260156	CORL105	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.009229385395277345	[531]	[502,564,831,635]	0	hSpCas9	negative selection	6562172
201754648	201754671	2	-	27260156	CORL105	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.24504843012057098	[231]	[372,209,364,349]	4	hSpCas9	negative selection	6562173
201767241	201767264	2	+	27260156	HS294T	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.16053861173148085	[528]	[133,227,266,306]	2	hSpCas9	negative selection	6619140
201754502	201754525	2	-	27260156	HS294T	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.20039398972541644	[769]	[196,271,228,359]	-3	hSpCas9	negative selection	6619141
201757632	201757655	2	-	27260156	HS294T	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.09265114817127496	[383]	[55,203,104,208]	-1	hSpCas9	negative selection	6619142
201767328	201767351	2	+	27260156	HS294T	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.2338737587878924	[781]	[269,558,249,340]	3	hSpCas9	negative selection	6683422
201757669	201757692	2	+	27260156	HS294T	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.0846824006581148	[531]	[195,228,148,200]	-1	hSpCas9	negative selection	6683423
201754648	201754671	2	-	27260156	HS294T	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.11095477130669962	[231]	[162,69,54,92]	1	hSpCas9	negative selection	6683424
201767241	201767264	2	+	27260156	HCC44	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.186630776252098	[528]	[703,304,698,469]	-3	hSpCas9	negative selection	6740391
201754502	201754525	2	-	27260156	HCC44	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.27247397852134364	[769]	[941,553,938,530]	-4	hSpCas9	negative selection	6740392
201757632	201757655	2	-	27260156	HCC44	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.22941278876431037	[383]	[501,267,487,270]	-4	hSpCas9	negative selection	6740393
201767328	201767351	2	+	27260156	HCC44	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.07663764960953601	[781]	[1198,681,982,927]	1	hSpCas9	negative selection	6804673
201757669	201757692	2	+	27260156	HCC44	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.20823344488684636	[531]	[397,501,659,533]	-3	hSpCas9	negative selection	6804674
201754648	201754671	2	-	27260156	HCC44	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.22887738682809766	[231]	[282,205,325,423]	3	hSpCas9	negative selection	6804675
201767241	201767264	2	+	27260156	G402	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.02112621381905469	[528]	[714,406,691,790]	0	hSpCas9	negative selection	6861642
201754502	201754525	2	-	27260156	G402	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.38465970289661644	[769]	[1078,719,498,633]	-5	hSpCas9	negative selection	6861643
201757632	201757655	2	-	27260156	G402	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.2893090892527306	[383]	[321,326,380,484]	-4	hSpCas9	negative selection	6861644
201767328	201767351	2	+	27260156	G402	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.06800449823939914	[781]	[875,1054,884,828]	-1	hSpCas9	negative selection	6925924
201757669	201757692	2	+	27260156	G402	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.06417548051740152	[531]	[963,449,616,495]	-1	hSpCas9	negative selection	6925925
201754648	201754671	2	-	27260156	G402	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.16821211063726949	[231]	[426,355,355,157]	2	hSpCas9	negative selection	6925926
201767241	201767264	2	+	27260156	L33	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.259915855813159	[528]	[654,223,391,706]	5	hSpCas9	negative selection	6982893
201754502	201754525	2	-	27260156	L33	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.08159551731318082	[769]	[805,341,550,742]	1	hSpCas9	negative selection	6982894
201757632	201757655	2	-	27260156	L33	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.018026410784258318	[383]	[446,142,221,365]	0	hSpCas9	negative selection	6982895
201767328	201767351	2	+	27260156	L33	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.05587392153334225	[781]	[755,317,408,824]	-1	hSpCas9	negative selection	7047175
201757669	201757692	2	+	27260156	L33	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.29801480175361794	[531]	[374,186,304,415]	-6	hSpCas9	negative selection	7047176
201754648	201754671	2	-	27260156	L33	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.07692535140709367	[231]	[270,111,143,204]	1	hSpCas9	negative selection	7047177
201767241	201767264	2	+	27260156	K562	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.10078737324236262	[528]	[542,382,772,329]	1	hSpCas9	negative selection	7104144
201754502	201754525	2	-	27260156	K562	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.10235802966888474	[769]	[774,962,516,695]	1	hSpCas9	negative selection	7104145
201757632	201757655	2	-	27260156	K562	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.14090757632035367	[383]	[435,376,172,504]	1	hSpCas9	negative selection	7104146
201767328	201767351	2	+	27260156	K562	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.16434623174539875	[781]	[1139,663,745,601]	2	hSpCas9	negative selection	7168426
201757669	201757692	2	+	27260156	K562	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.1469556074937293	[531]	[344,455,304,574]	-2	hSpCas9	negative selection	7168427
201754648	201754671	2	-	27260156	K562	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.6637620423241174	[231]	[272,85,654,277]	8	hSpCas9	negative selection	7168428
201767241	201767264	2	+	27260156	HT29	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.1345671328929515	[528]	[694,846,762,544]	2	hSpCas9	negative selection	7225395
201754502	201754525	2	-	27260156	HT29	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.010499379659534402	[769]	[892,1119,1080,710]	0	hSpCas9	negative selection	7225396
201757632	201757655	2	-	27260156	HT29	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.5110518987351064	[383]	[296,317,409,284]	-7	hSpCas9	negative selection	7225397
201767328	201767351	2	+	27260156	HT29	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.07386735251867749	[781]	[996,868,918,833]	-1	hSpCas9	negative selection	7289677
201757669	201757692	2	+	27260156	HT29	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.40207038868594847	[531]	[445,575,561,386]	-6	hSpCas9	negative selection	7289678
201754648	201754671	2	-	27260156	HT29	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.3796607296709814	[231]	[401,269,425,361]	7	hSpCas9	negative selection	7289679
201767241	201767264	2	+	27260156	MHHES1	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.09977853787647709	[528]	[746,789,598,470]	1	hSpCas9	negative selection	7346646
201754502	201754525	2	-	27260156	MHHES1	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.2311254617990453	[769]	[577,728,874,736]	-4	hSpCas9	negative selection	7346647
201757632	201757655	2	-	27260156	MHHES1	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.3824688591218137	[383]	[483,256,283,309]	-6	hSpCas9	negative selection	7346648
201767328	201767351	2	+	27260156	MHHES1	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.13858494815331923	[781]	[970,1244,1010,716]	2	hSpCas9	negative selection	7410928
201757669	201757692	2	+	27260156	MHHES1	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.17053824853079363	[531]	[773,494,606,317]	-3	hSpCas9	negative selection	7410929
201754648	201754671	2	-	27260156	MHHES1	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.13209968143274897	[231]	[375,329,144,298]	2	hSpCas9	negative selection	7410930
201767241	201767264	2	+	27260156	MEWO	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.23081836296259922	[528]	[502,394,382]	-5	hSpCas9	negative selection	7467897
201754502	201754525	2	-	27260156	MEWO	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.09096624865283587	[769]	[746,598,696]	-2	hSpCas9	negative selection	7467898
201757632	201757655	2	-	27260156	MEWO	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.11166262588031589	[383]	[374,261,368]	-2	hSpCas9	negative selection	7467899
201767328	201767351	2	+	27260156	MEWO	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.08017909306310311	[781]	[895,739,707]	1	hSpCas9	negative selection	7532179
201757669	201757692	2	+	27260156	MEWO	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.10272561634301405	[531]	[549,501,354]	-2	hSpCas9	negative selection	7532180
201754648	201754671	2	-	27260156	MEWO	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	-0.010050882623715118	[231]	[180,192,265]	0	hSpCas9	negative selection	7532181
201767241	201767264	2	+	27260156	LNCAPCLONEFGC	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.16279721322993948	[528]	[385,418,438,470]	-3	hSpCas9	negative selection	7589148
201754502	201754525	2	-	27260156	LNCAPCLONEFGC	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.2220763452678325	[769]	[595,548,753,518]	-4	hSpCas9	negative selection	7589149
201757632	201757655	2	-	27260156	LNCAPCLONEFGC	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.28788966228511537	[383]	[202,366,266,295]	-4	hSpCas9	negative selection	7589150
201767328	201767351	2	+	27260156	LNCAPCLONEFGC	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.1360912583491154	[781]	[702,650,911,876]	2	hSpCas9	negative selection	7653430
201757669	201757692	2	+	27260156	LNCAPCLONEFGC	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.021335484877650884	[531]	[515,397,593,412]	0	hSpCas9	negative selection	7653431
201754648	201754671	2	-	27260156	LNCAPCLONEFGC	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.38321612910296987	[231]	[228,275,361,242]	6	hSpCas9	negative selection	7653432
201767241	201767264	2	+	27260156	PANC0327	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.318271097661296	[528]	[364,472,328,326]	-5	hSpCas9	negative selection	7710399
201754502	201754525	2	-	27260156	PANC0327	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.4728141982656322	[769]	[744,469,470,308]	-6	hSpCas9	negative selection	7710400
201757632	201757655	2	-	27260156	PANC0327	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.15145480970307168	[383]	[314,374,175,353]	-2	hSpCas9	negative selection	7710401
201767328	201767351	2	+	27260156	PANC0327	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.46408586688895515	[781]	[1278,615,919,1087]	7	hSpCas9	negative selection	7774681
201757669	201757692	2	+	27260156	PANC0327	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.035993978478378985	[531]	[411,560,432,515]	0	hSpCas9	negative selection	7774682
201754648	201754671	2	-	27260156	PANC0327	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.5891646086905605	[231]	[179,226,329,502]	8	hSpCas9	negative selection	7774683
201767241	201767264	2	+	27260156	NCIH2009	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.2204352205589112	[528]	[971,683,950]	3	hSpCas9	negative selection	7831650
201754502	201754525	2	-	27260156	NCIH2009	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.001982719995926918	[769]	[1605,886,844]	0	hSpCas9	negative selection	7831651
201757632	201757655	2	-	27260156	NCIH2009	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.0378818091813139	[383]	[552,573,444]	0	hSpCas9	negative selection	7831652
201767328	201767351	2	+	27260156	NCIH2009	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.10123475115132496	[781]	[1557,912,1123]	1	hSpCas9	negative selection	7895932
201757669	201757692	2	+	27260156	NCIH2009	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.1627483062211274	[531]	[804,648,564]	-2	hSpCas9	negative selection	7895933
201754648	201754671	2	-	27260156	NCIH2009	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.15357528968967238	[231]	[532,256,326]	2	hSpCas9	negative selection	7895934
201767241	201767264	2	+	27260156	NCIH1373	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.07430602455156923	[528]	[861,623,340,187]	0	hSpCas9	negative selection	7952901
201754502	201754525	2	-	27260156	NCIH1373	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.1265363238219097	[769]	[1519,477,1070,216]	1	hSpCas9	negative selection	7952902
201757632	201757655	2	-	27260156	NCIH1373	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.3380899639039612	[383]	[320,507,240,69]	-3	hSpCas9	negative selection	7952903
201767328	201767351	2	+	27260156	NCIH1373	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.3936624553203736	[781]	[1768,1043,711,313]	4	hSpCas9	negative selection	8017183
201757669	201757692	2	+	27260156	NCIH1373	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.48905841402268097	[531]	[471,276,297,181]	-5	hSpCas9	negative selection	8017184
201754648	201754671	2	-	27260156	NCIH1373	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	-0.6883311065721112	[231]	[89,210,124,53]	-6	hSpCas9	negative selection	8017185
201767241	201767264	2	+	27260156	PATU8902	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.6031937161176424	[528]	[1155,867,847,1738]	6	hSpCas9	negative selection	8074152
201754502	201754525	2	-	27260156	PATU8902	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.7540342039485297	[769]	[553,744,541,734]	-6	hSpCas9	negative selection	8074153
201757632	201757655	2	-	27260156	PATU8902	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.8105961201109376	[383]	[470,257,232,266]	-6	hSpCas9	negative selection	8074154
201767328	201767351	2	+	27260156	PATU8902	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.3300782569256593	[781]	[860,1218,1181,2378]	3	hSpCas9	negative selection	8138434
201757669	201757692	2	+	27260156	PATU8902	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	0.18512533287566446	[531]	[524,705,1047,1059]	1	hSpCas9	negative selection	8138435
201754648	201754671	2	-	27260156	PATU8902	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.3174902641867108	[231]	[392,233,591,329]	3	hSpCas9	negative selection	8138436
201767241	201767264	2	+	27260156	PANC1	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.22181642370178947	[528]	[600,685,458,413]	3	hSpCas9	negative selection	8195403
201754502	201754525	2	-	27260156	PANC1	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.08103494082138063	[769]	[487,822,763,483]	-1	hSpCas9	negative selection	8195404
201757632	201757655	2	-	27260156	PANC1	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.4266035878362483	[383]	[281,367,219,147]	-6	hSpCas9	negative selection	8195405
201767328	201767351	2	+	27260156	PANC1	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.08257162839923193	[781]	[825,665,601,723]	1	hSpCas9	negative selection	8259685
201757669	201757692	2	+	27260156	PANC1	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.05197379765091978	[531]	[450,578,392,371]	-1	hSpCas9	negative selection	8259686
201754648	201754671	2	-	27260156	PANC1	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.22969217684929344	[231]	[241,373,185,167]	3	hSpCas9	negative selection	8259687
201767241	201767264	2	+	27260156	PANC0813	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.14995348904533404	[528]	[766,642,548,797]	2	hSpCas9	negative selection	8316654
201754502	201754525	2	-	27260156	PANC0813	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.2001454573491651	[769]	[944,1139,1180,888]	3	hSpCas9	negative selection	8316655
201757632	201757655	2	-	27260156	PANC0813	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.4008034247058946	[383]	[472,256,373,277]	-6	hSpCas9	negative selection	8316656
201767328	201767351	2	+	27260156	PANC0813	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.32053087608404884	[781]	[1008,1075,1175,1303]	5	hSpCas9	negative selection	8380936
201757669	201757692	2	+	27260156	PANC0813	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.1980067074259761	[531]	[532,608,493,540]	-3	hSpCas9	negative selection	8380937
201754648	201754671	2	-	27260156	PANC0813	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	-0.07588831140723262	[231]	[214,268,254,288]	-1	hSpCas9	negative selection	8380938
201767241	201767264	2	+	27260156	RDES	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.03309397440931186	[528]	[479,634,604,672]	0	hSpCas9	negative selection	8437905
201754502	201754525	2	-	27260156	RDES	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.17633302565031783	[769]	[623,698,927,930]	-3	hSpCas9	negative selection	8437906
201757632	201757655	2	-	27260156	RDES	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.21822844622564785	[383]	[267,429,387,451]	-4	hSpCas9	negative selection	8437907
201767328	201767351	2	+	27260156	RDES	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.04981279592007837	[781]	[799,716,1103,1165]	0	hSpCas9	negative selection	8502187
201757669	201757692	2	+	27260156	RDES	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.012037161732160656	[531]	[476,433,747,835]	0	hSpCas9	negative selection	8502188
201754648	201754671	2	-	27260156	RDES	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.1534926985789108	[231]	[296,275,222,394]	2	hSpCas9	negative selection	8502189
201767241	201767264	2	+	27260156	PC3	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.01235883220783937	[528]	[396,446,796,595]	0	hSpCas9	negative selection	8559156
201754502	201754525	2	-	27260156	PC3	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.01561376312178131	[769]	[647,719,1118,707]	0	hSpCas9	negative selection	8559157
201757632	201757655	2	-	27260156	PC3	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.2631230589762953	[383]	[200,345,549,285]	-5	hSpCas9	negative selection	8559158
201767328	201767351	2	+	27260156	PC3	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.20262094384555007	[781]	[469,1044,1168,1121]	4	hSpCas9	negative selection	8623438
201757669	201757692	2	+	27260156	PC3	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.3667240722239991	[531]	[244,429,501,541]	-7	hSpCas9	negative selection	8623439
201754648	201754671	2	-	27260156	PC3	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.45800256886656654	[231]	[218,251,465,408]	8	hSpCas9	negative selection	8623440
201767241	201767264	2	+	27260156	PATU8988T	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	-0.005393579857766118	[528]	[455,519,545,515]	0	hSpCas9	negative selection	8680407
201754502	201754525	2	-	27260156	PATU8988T	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.13788468314011326	[769]	[659,809,579,667]	-2	hSpCas9	negative selection	8680408
201757632	201757655	2	-	27260156	PATU8988T	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	0.06575591707081616	[383]	[449,275,303,524]	1	hSpCas9	negative selection	8680409
201767328	201767351	2	+	27260156	PATU8988T	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.15845611473540733	[781]	[717,821,959,871]	2	hSpCas9	negative selection	8744689
201757669	201757692	2	+	27260156	PATU8988T	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.14869896117669032	[531]	[632,394,561,238]	-3	hSpCas9	negative selection	8744690
201754648	201754671	2	-	27260156	PATU8988T	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.29154391934047985	[231]	[145,287,282,390]	5	hSpCas9	negative selection	8744691
201767241	201767264	2	+	27260156	T47D	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.3512225546486746	[528]	[872,675,732,875]	7	hSpCas9	negative selection	8801658
201754502	201754525	2	-	27260156	T47D	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.08162538523987672	[769]	[897,766,846,886]	-2	hSpCas9	negative selection	8801659
201757632	201757655	2	-	27260156	T47D	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.07335665206050318	[383]	[485,366,383,470]	-2	hSpCas9	negative selection	8801660
201767328	201767351	2	+	27260156	T47D	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.008886062598952749	[781]	[928,866,974,850]	0	hSpCas9	negative selection	8865940
201757669	201757692	2	+	27260156	T47D	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.2215647738958656	[531]	[590,490,495,552]	-5	hSpCas9	negative selection	8865941
201754648	201754671	2	-	27260156	T47D	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.2522501910140589	[231]	[342,299,334,310]	5	hSpCas9	negative selection	8865942
201767241	201767264	2	+	27260156	SU8686	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.17262029574719126	[528]	[551,736,404,656]	3	hSpCas9	negative selection	8922909
201754502	201754525	2	-	27260156	SU8686	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.012533791988708853	[769]	[876,660,682,804]	0	hSpCas9	negative selection	8922910
201757632	201757655	2	-	27260156	SU8686	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.5130354279623752	[383]	[252,179,301,358]	-7	hSpCas9	negative selection	8922911
201767328	201767351	2	+	27260156	SU8686	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	-0.07463577236194474	[781]	[592,638,677,1118]	-1	hSpCas9	negative selection	8987191
201757669	201757692	2	+	27260156	SU8686	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.3391193927741649	[531]	[355,435,320,579]	-5	hSpCas9	negative selection	8987192
201754648	201754671	2	-	27260156	SU8686	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.17027235573387556	[231]	[223,248,245,330]	3	hSpCas9	negative selection	8987193
201767241	201767264	2	+	27260156	SKES1	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.04570201803991189	[528]	[568,549,582,481]	1	hSpCas9	negative selection	9044160
201754502	201754525	2	-	27260156	SKES1	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.0865160004255564	[769]	[817,912,551,649]	-2	hSpCas9	negative selection	9044161
201757632	201757655	2	-	27260156	SKES1	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.21891054077670669	[383]	[398,350,294,285]	-5	hSpCas9	negative selection	9044162
201767328	201767351	2	+	27260156	SKES1	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.13174123463198228	[781]	[1016,941,906,605]	3	hSpCas9	negative selection	9108442
201757669	201757692	2	+	27260156	SKES1	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.3016705086720659	[531]	[494,516,360,371]	-6	hSpCas9	negative selection	9108443
201754648	201754671	2	-	27260156	SKES1	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.04220221463060492	[231]	[259,195,239,250]	0	hSpCas9	negative selection	9108444
201767241	201767264	2	+	27260156	TOV112D	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.04414882369015047	[528]	[633,492,486,563]	0	hSpCas9	negative selection	9165411
201754502	201754525	2	-	27260156	TOV112D	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	0.06244127033605651	[769]	[592,1081,894,702]	1	hSpCas9	negative selection	9165412
201757632	201757655	2	-	27260156	TOV112D	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.16471759737314356	[383]	[378,494,222,315]	-3	hSpCas9	negative selection	9165413
201767328	201767351	2	+	27260156	TOV112D	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.1455535897462925	[781]	[1056,1211,679,622]	3	hSpCas9	negative selection	9229693
201757669	201757692	2	+	27260156	TOV112D	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.3495836721596608	[531]	[391,511,411,377]	-6	hSpCas9	negative selection	9229694
201754648	201754671	2	-	27260156	TOV112D	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.0597516739002969	[231]	[155,347,308,175]	1	hSpCas9	negative selection	9229695
201767241	201767264	2	+	27260156	TC71	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.2712495485179153	[528]	[727,602,711,692]	6	hSpCas9	negative selection	9286662
201754502	201754525	2	-	27260156	TC71	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.10857500880623305	[769]	[708,761,759,836]	-3	hSpCas9	negative selection	9286663
201757632	201757655	2	-	27260156	TC71	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.45798116933968014	[383]	[264,309,329,292]	-8	hSpCas9	negative selection	9286664
201767328	201767351	2	+	27260156	TC71	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.02548892737744446	[781]	[1022,734,855,790]	0	hSpCas9	negative selection	9350944
201757669	201757692	2	+	27260156	TC71	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.27951837492765164	[531]	[502,411,430,537]	-6	hSpCas9	negative selection	9350945
201754648	201754671	2	-	27260156	TC71	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.611678291917682	[231]	[369,440,358,348]	9	hSpCas9	negative selection	9350946
201767241	201767264	2	+	27260156	TC32	viability	GAACTCCATGTTTCACTCCGAGG	ALS2	ENSG00000003393	0.028213377770159864	[528]	[514,303,650,636]	0	hSpCas9	negative selection	9407913
201754502	201754525	2	-	27260156	TC32	viability	GGCACGGCGATGTTCTGCCTAGG	ALS2	ENSG00000003393	-0.18048488279824026	[769]	[601,429,934,687]	-3	hSpCas9	negative selection	9407914
201757632	201757655	2	-	27260156	TC32	viability	GTGGCTGCTACTTATGAAGCTGG	ALS2	ENSG00000003393	-0.2503971098184776	[383]	[213,236,351,445]	-4	hSpCas9	negative selection	9407915
201767328	201767351	2	+	27260156	TC32	viability	CTGCCTGCCAGATATGGACCAGG	ALS2	ENSG00000003393	0.0942090412394021	[781]	[823,554,874,942]	1	hSpCas9	negative selection	9472195
201757669	201757692	2	+	27260156	TC32	viability	CAGATGCACAAGAGACCACCAGG	ALS2	ENSG00000003393	-0.07393155117469313	[531]	[370,441,603,502]	-1	hSpCas9	negative selection	9472196
201754648	201754671	2	-	27260156	TC32	viability	TTCCCCCAGGCTCTTAAGAAAGG	ALS2	ENSG00000003393	0.2920279236538069	[231]	[258,205,385,243]	5	hSpCas9	negative selection	9472197
201749711	201749734	2	-	27869803	HPAFII	viability after 27 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.05124618423999949	[128]	[108,37,NaN]	0	hSpCas9	negative selection	9572995
201753154	201753177	2	+	27869803	HPAFII	viability after 27 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.8257774999404973	[458]	[598,284,NaN]	6	hSpCas9	negative selection	9572996
201757504	201757527	2	-	27869803	HPAFII	viability after 27 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.855195171028031	[456]	[318,530,NaN]	7	hSpCas9	negative selection	9572997
201761541	201761564	2	+	27869803	HPAFII	viability after 27 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-4.2908430647578	[175]	[1,6,NaN]	-9	hSpCas9	negative selection	9572998
201767242	201767265	2	+	27869803	HPAFII	viability after 27 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.2731168958614256	[153]	[42,86,NaN]	-2	hSpCas9	negative selection	9572999
201768865	201768888	2	-	27869803	HPAFII	viability after 27 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.2512300435311449	[247]	[108,109,NaN]	-2	hSpCas9	negative selection	9573000
201749711	201749734	2	-	27869803	HPAFII	viability after 15 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.5847111402066926	[128]	[284,159,NaN]	6	hSpCas9	negative selection	9655444
201753154	201753177	2	+	27869803	HPAFII	viability after 15 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.4799771754765624	[458]	[1221,355,NaN]	5	hSpCas9	negative selection	9655445
201757504	201757527	2	-	27869803	HPAFII	viability after 15 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.25775210251418046	[456]	[704,513,NaN]	3	hSpCas9	negative selection	9655446
201761541	201761564	2	+	27869803	HPAFII	viability after 15 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-1.2896844258583915	[175]	[122,48,NaN]	-8	hSpCas9	negative selection	9655447
201767242	201767265	2	+	27869803	HPAFII	viability after 15 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.2288793539123989	[153]	[258,67,NaN]	-3	hSpCas9	negative selection	9655448
201768865	201768888	2	-	27869803	HPAFII	viability after 15 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.1174497443609172	[247]	[360,173,NaN]	-1	hSpCas9	negative selection	9655449
201749711	201749734	2	-	27869803	ASPC1	viability after 36 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.7524680220824517	[420]	[649,129,55]	7	hSpCas9	negative selection	9737893
201753154	201753177	2	+	27869803	ASPC1	viability after 36 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.15537344407193476	[1011]	[376,430,370]	1	hSpCas9	negative selection	9737894
201757504	201757527	2	-	27869803	ASPC1	viability after 36 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.7502437076939444	[859]	[874,271,424]	7	hSpCas9	negative selection	9737895
201761541	201761564	2	+	27869803	ASPC1	viability after 36 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.26383806665143905	[453]	[186,97,118]	-3	hSpCas9	negative selection	9737896
201767242	201767265	2	+	27869803	ASPC1	viability after 36 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.4353255842836401	[421]	[190,112,46]	-4	hSpCas9	negative selection	9737897
201768865	201768888	2	-	27869803	ASPC1	viability after 36 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.41941044948410144	[519]	[262,272,201]	4	hSpCas9	negative selection	9737898
201749711	201749734	2	-	27869803	PATU8988S	viability after 35 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.2398801936241145	[348]	[159,171,NaN]	2	hSpCas9	negative selection	9820342
201753154	201753177	2	+	27869803	PATU8988S	viability after 35 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.5195688212983016	[881]	[388,629,NaN]	6	hSpCas9	negative selection	9820343
201757504	201757527	2	-	27869803	PATU8988S	viability after 35 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.10789553921744038	[749]	[333,316,NaN]	1	hSpCas9	negative selection	9820344
201761541	201761564	2	+	27869803	PATU8988S	viability after 35 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-1.4012165089558195	[304]	[49,42,NaN]	-8	hSpCas9	negative selection	9820345
201767242	201767265	2	+	27869803	PATU8988S	viability after 35 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	0.03039616965713554	[242]	[78,120,NaN]	0	hSpCas9	negative selection	9820346
201768865	201768888	2	-	27869803	PATU8988S	viability after 35 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.5102551959917957	[398]	[176,280,NaN]	5	hSpCas9	negative selection	9820347
201749711	201749734	2	-	27869803	PATU8988S	viability after 31 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.711039495736751	[348]	[251,196,NaN]	8	hSpCas9	negative selection	9902791
201753154	201753177	2	+	27869803	PATU8988S	viability after 31 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	0.3967572536147501	[881]	[356,597,NaN]	5	hSpCas9	negative selection	9902792
201757504	201757527	2	-	27869803	PATU8988S	viability after 31 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.4150631657628801	[749]	[352,456,NaN]	5	hSpCas9	negative selection	9902793
201761541	201761564	2	+	27869803	PATU8988S	viability after 31 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.892400698314532	[304]	[50,83,NaN]	-7	hSpCas9	negative selection	9902794
201767242	201767265	2	+	27869803	PATU8988S	viability after 31 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.5796562386718069	[242]	[37,98,NaN]	-6	hSpCas9	negative selection	9902795
201768865	201768888	2	-	27869803	PATU8988S	viability after 31 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.28071190181493666	[398]	[154,241,NaN]	3	hSpCas9	negative selection	9902796
201749711	201749734	2	-	27869803	HPAFII	viability after 35 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	0.30018346956921726	[128]	[78,81,NaN]	2	hSpCas9	negative selection	9985240
201753154	201753177	2	+	27869803	HPAFII	viability after 35 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	1.4756933925865505	[458]	[800,471,NaN]	8	hSpCas9	negative selection	9985241
201757504	201757527	2	-	27869803	HPAFII	viability after 35 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	0.901598737413305	[456]	[244,642,NaN]	6	hSpCas9	negative selection	9985242
201761541	201761564	2	+	27869803	HPAFII	viability after 35 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-3.7452326310987645	[175]	[0,12,NaN]	-9	hSpCas9	negative selection	9985243
201767242	201767265	2	+	27869803	HPAFII	viability after 35 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-1.4657811594955064	[153]	[7,50,NaN]	-7	hSpCas9	negative selection	9985244
201768865	201768888	2	-	27869803	HPAFII	viability after 35 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.1671987726930787	[247]	[84,141,NaN]	-1	hSpCas9	negative selection	9985245
201749711	201749734	2	-	27869803	HPAFII	viability after 31 days	AACAGTTCCTCGTCTTGCAAAGG	ALS2	ENSG00000003393	-0.13799699580499758	[128]	[49,82,NaN]	-1	hSpCas9	negative selection	10067689
201753154	201753177	2	+	27869803	HPAFII	viability after 31 days	TCGCAGTAAGTGCAAGAGAATGG	ALS2	ENSG00000003393	1.0860033602393697	[458]	[721,355,NaN]	7	hSpCas9	negative selection	10067690
201757504	201757527	2	-	27869803	HPAFII	viability after 31 days	CAGGGAAGAACAGGTTAAACAGG	ALS2	ENSG00000003393	1.244553283497226	[456]	[455,772,NaN]	8	hSpCas9	negative selection	10067691
201761541	201761564	2	+	27869803	HPAFII	viability after 31 days	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-3.8727003865451652	[175]	[0,12,NaN]	-9	hSpCas9	negative selection	10067692
201767242	201767265	2	+	27869803	HPAFII	viability after 31 days	AACTCCATGTTTCACTCCGAGGG	ALS2	ENSG00000003393	-0.4730823637365056	[153]	[56,67,NaN]	-3	hSpCas9	negative selection	10067693
201768865	201768888	2	-	27869803	HPAFII	viability after 31 days	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.43642712707404585	[247]	[65,142,NaN]	-3	hSpCas9	negative selection	10067694
201768865	201768888	2	-	28162770	P31FUJ	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.617827134626783	[110]	[84]	-5	hSpCas9	negative selection	10109736
201767358	201767381	2	-	28162770	P31FUJ	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.2977125122844011	[251]	[363]	3	hSpCas9	negative selection	10109737
201767285	201767308	2	-	28162770	P31FUJ	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-0.1656880085558412	[20]	[21]	-2	hSpCas9	negative selection	10109738
201761157	201761180	2	+	28162770	P31FUJ	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-1.2328022044143785	[237]	[118]	-7	hSpCas9	negative selection	10109739
201761776	201761799	2	-	28162770	P31FUJ	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	0.6779304574885341	[24]	[46]	7	hSpCas9	negative selection	10109740
201761541	201761564	2	+	28162770	P31FUJ	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	2.5290380583908565	[114]	[779]	9	hSpCas9	negative selection	10109741
201761368	201761391	2	-	28162770	P31FUJ	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.6695492315789725	[381]	[713]	7	hSpCas9	negative selection	10109742
201761339	201761362	2	+	28162770	P31FUJ	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.9483488149456789	[155]	[94]	-6	hSpCas9	negative selection	10109743
201760928	201760951	2	+	28162770	P31FUJ	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.715454220491623	[368]	[711]	7	hSpCas9	negative selection	10109744
201760873	201760896	2	+	28162770	P31FUJ	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.312228824033046	[231]	[676]	9	hSpCas9	negative selection	10109745
201768865	201768888	2	-	28162770	TF1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10279102
201767358	201767381	2	-	28162770	TF1	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10279103
201767285	201767308	2	-	28162770	TF1	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10279104
201761157	201761180	2	+	28162770	TF1	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10279105
201761776	201761799	2	-	28162770	TF1	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10279106
201761541	201761564	2	+	28162770	TF1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10279107
201761368	201761391	2	-	28162770	TF1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10279108
201761339	201761362	2	+	28162770	TF1	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10279109
201760928	201760951	2	+	28162770	TF1	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10279110
201760873	201760896	2	+	28162770	TF1	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	NaN	[NaN]	[386]	1	hSpCas9	negative selection	10279111
201768865	201768888	2	-	28162770	SKM1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	1.0024267373945401	[23]	[84]	8	hSpCas9	negative selection	10448468
201767358	201767381	2	-	28162770	SKM1	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.3662020371386157	[60]	[138]	3	hSpCas9	negative selection	10448469
201767285	201767308	2	-	28162770	SKM1	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	0.7629608026991506	[9]	[29]	7	hSpCas9	negative selection	10448470
201761157	201761180	2	+	28162770	SKM1	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.7631080089684371	[71]	[74]	-5	hSpCas9	negative selection	10448471
201761776	201761799	2	-	28162770	SKM1	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-0.38142910663602425	[13]	[18]	-3	hSpCas9	negative selection	10448472
201761541	201761564	2	+	28162770	SKM1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.07846262842708004	[44]	[83]	0	hSpCas9	negative selection	10448473
201761368	201761391	2	-	28162770	SKM1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.19905991750582436	[67]	[137]	2	hSpCas9	negative selection	10448474
201761339	201761362	2	+	28162770	SKM1	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10448475
201760928	201760951	2	+	28162770	SKM1	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.7581915585512786	[100]	[301]	7	hSpCas9	negative selection	10448476
201760873	201760896	2	+	28162770	SKM1	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.423110799814526	[53]	[255]	9	hSpCas9	negative selection	10448477
201768865	201768888	2	-	28162770	SKM1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	1.0024267373945401	[23]	[84]	8	hSpCas9	negative selection	10617834
201767358	201767381	2	-	28162770	SKM1	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.3662020371386157	[60]	[138]	3	hSpCas9	negative selection	10617835
201767285	201767308	2	-	28162770	SKM1	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	0.7629608026991506	[9]	[29]	7	hSpCas9	negative selection	10617836
201761157	201761180	2	+	28162770	SKM1	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.7631080089684371	[71]	[74]	-5	hSpCas9	negative selection	10617837
201761776	201761799	2	-	28162770	SKM1	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-0.38142910663602425	[13]	[18]	-3	hSpCas9	negative selection	10617838
201761541	201761564	2	+	28162770	SKM1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.07846262842708004	[44]	[83]	0	hSpCas9	negative selection	10617839
201761368	201761391	2	-	28162770	SKM1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.19905991750582436	[67]	[137]	2	hSpCas9	negative selection	10617840
201761339	201761362	2	+	28162770	SKM1	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10617841
201760928	201760951	2	+	28162770	SKM1	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.7581915585512786	[100]	[301]	7	hSpCas9	negative selection	10617842
201760873	201760896	2	+	28162770	SKM1	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.423110799814526	[53]	[255]	9	hSpCas9	negative selection	10617843
201768865	201768888	2	-	28162770	PL21	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.9865441413900312	[108]	[93]	8	hSpCas9	negative selection	10787200
201767358	201767381	2	-	28162770	PL21	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.6785540892885462	[227]	[61]	-5	hSpCas9	negative selection	10787201
201767285	201767308	2	-	28162770	PL21	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	0.0022002368774112213	[38]	[16]	0	hSpCas9	negative selection	10787202
201761157	201761180	2	+	28162770	PL21	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.07619161395793157	[217]	[89]	0	hSpCas9	negative selection	10787203
201761776	201761799	2	-	28162770	PL21	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	0.48024753368205575	[27]	[16]	4	hSpCas9	negative selection	10787204
201761541	201761564	2	+	28162770	PL21	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-1.4799801192721762	[140]	[21]	-7	hSpCas9	negative selection	10787205
201761368	201761391	2	-	28162770	PL21	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.5447877858767659	[251]	[159]	5	hSpCas9	negative selection	10787206
201761339	201761362	2	+	28162770	PL21	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.20039831509440853	[131]	[49]	-1	hSpCas9	negative selection	10787207
201760928	201760951	2	+	28162770	PL21	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.222551457332959	[377]	[140]	-2	hSpCas9	negative selection	10787208
201760873	201760896	2	+	28162770	PL21	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.0512762285748376	[203]	[183]	8	hSpCas9	negative selection	10787209
201768865	201768888	2	-	28162770	P31FUJ	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.617827134626783	[110]	[84]	-5	hSpCas9	negative selection	10956566
201767358	201767381	2	-	28162770	P31FUJ	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.2977125122844011	[251]	[363]	3	hSpCas9	negative selection	10956567
201767285	201767308	2	-	28162770	P31FUJ	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-0.1656880085558412	[20]	[21]	-2	hSpCas9	negative selection	10956568
201761157	201761180	2	+	28162770	P31FUJ	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-1.2328022044143785	[237]	[118]	-7	hSpCas9	negative selection	10956569
201761776	201761799	2	-	28162770	P31FUJ	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	0.6779304574885341	[24]	[46]	7	hSpCas9	negative selection	10956570
201761541	201761564	2	+	28162770	P31FUJ	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	2.5290380583908565	[114]	[779]	9	hSpCas9	negative selection	10956571
201761368	201761391	2	-	28162770	P31FUJ	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.6695492315789725	[381]	[713]	7	hSpCas9	negative selection	10956572
201761339	201761362	2	+	28162770	P31FUJ	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.9483488149456789	[155]	[94]	-6	hSpCas9	negative selection	10956573
201760928	201760951	2	+	28162770	P31FUJ	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.715454220491623	[368]	[711]	7	hSpCas9	negative selection	10956574
201760873	201760896	2	+	28162770	P31FUJ	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.312228824033046	[231]	[676]	9	hSpCas9	negative selection	10956575
201768865	201768888	2	-	28162770	OCIAML5	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-1.9248229132993109	[60]	[28]	-7	hSpCas9	negative selection	11125932
201767358	201767381	2	-	28162770	OCIAML5	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.2494020684093817	[161]	[245]	-2	hSpCas9	negative selection	11125933
201767285	201767308	2	-	28162770	OCIAML5	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	2.2140226195937753	[7]	[66]	9	hSpCas9	negative selection	11125934
201761157	201761180	2	+	28162770	OCIAML5	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-1.4460742111881602	[159]	[105]	-7	hSpCas9	negative selection	11125935
201761776	201761799	2	-	28162770	OCIAML5	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-1.9516022444149113	[29]	[13]	-8	hSpCas9	negative selection	11125936
201761541	201761564	2	+	28162770	OCIAML5	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.4995501561432117	[111]	[142]	-3	hSpCas9	negative selection	11125937
201761368	201761391	2	-	28162770	OCIAML5	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.45215952228990625	[163]	[404]	4	hSpCas9	negative selection	11125938
201761339	201761362	2	+	28162770	OCIAML5	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-1.2087600839120358	[104]	[81]	-6	hSpCas9	negative selection	11125939
201760928	201760951	2	+	28162770	OCIAML5	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.18006605007681198	[221]	[453]	1	hSpCas9	negative selection	11125940
201760873	201760896	2	+	28162770	OCIAML5	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.5655448720786733	[139]	[373]	5	hSpCas9	negative selection	11125941
201768865	201768888	2	-	28162770	EOL1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	1.0751074481459157	[199]	[221]	8	hSpCas9	negative selection	11295298
201767358	201767381	2	-	28162770	EOL1	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.9890880237652452	[305]	[319]	8	hSpCas9	negative selection	11295299
201767285	201767308	2	-	28162770	EOL1	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-0.3384866342632593	[47]	[19]	-3	hSpCas9	negative selection	11295300
201761157	201761180	2	+	28162770	EOL1	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.09447277301284673	[399]	[224]	0	hSpCas9	negative selection	11295301
201761776	201761799	2	-	28162770	EOL1	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	2.1901378823080853	[46]	[112]	9	hSpCas9	negative selection	11295302
201761541	201761564	2	+	28162770	EOL1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.249072977943936	[221]	[138]	2	hSpCas9	negative selection	11295303
201761368	201761391	2	-	28162770	EOL1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.3250857011542631	[299]	[197]	3	hSpCas9	negative selection	11295304
201761339	201761362	2	+	28162770	EOL1	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-1.188346284835399	[185]	[42]	-7	hSpCas9	negative selection	11295305
201760928	201760951	2	+	28162770	EOL1	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.7389921184144581	[405]	[356]	6	hSpCas9	negative selection	11295306
201760873	201760896	2	+	28162770	EOL1	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	1.7030556279799245	[266]	[457]	9	hSpCas9	negative selection	11295307
201768865	201768888	2	-	28162770	MOLM13	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.12259729359170612	[248]	[195]	0	hSpCas9	negative selection	11464664
201767358	201767381	2	-	28162770	MOLM13	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.15466990583422877	[310]	[201]	-1	hSpCas9	negative selection	11464665
201767285	201767308	2	-	28162770	MOLM13	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-1.4390012140639392	[44]	[11]	-6	hSpCas9	negative selection	11464666
201761157	201761180	2	+	28162770	MOLM13	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.41845383665985414	[365]	[197]	-2	hSpCas9	negative selection	11464667
201761776	201761799	2	-	28162770	MOLM13	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	1.2669766876185824	[49]	[86]	8	hSpCas9	negative selection	11464668
201761541	201761564	2	+	28162770	MOLM13	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.968582965368131	[187]	[265]	7	hSpCas9	negative selection	11464669
201761368	201761391	2	-	28162770	MOLM13	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	-0.16860341981665944	[341]	[219]	-1	hSpCas9	negative selection	11464670
201761339	201761362	2	+	28162770	MOLM13	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.8835829889567989	[147]	[57]	-5	hSpCas9	negative selection	11464671
201760928	201760951	2	+	28162770	MOLM13	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.675985831017071	[589]	[266]	-4	hSpCas9	negative selection	11464672
201760873	201760896	2	+	28162770	MOLM13	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.5092301769254782	[343]	[353]	4	hSpCas9	negative selection	11464673
201768865	201768888	2	-	28162770	HEL	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.4804674031014799	[140]	[125]	4	hSpCas9	negative selection	11634030
201767358	201767381	2	-	28162770	HEL	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.19832202734421664	[248]	[138]	-1	hSpCas9	negative selection	11634031
201767285	201767308	2	-	28162770	HEL	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	0.8406782096122658	[33]	[38]	7	hSpCas9	negative selection	11634032
201761157	201761180	2	+	28162770	HEL	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.7811223161562793	[297]	[327]	6	hSpCas9	negative selection	11634033
201761776	201761799	2	-	28162770	HEL	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-1.6791892628870055	[44]	[8]	-7	hSpCas9	negative selection	11634034
201761541	201761564	2	+	28162770	HEL	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.6382813193067994	[225]	[92]	-4	hSpCas9	negative selection	11634035
201761368	201761391	2	-	28162770	HEL	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	-0.45302015080507374	[217]	[101]	-3	hSpCas9	negative selection	11634036
201761339	201761362	2	+	28162770	HEL	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.04432185633953545	[160]	[99]	0	hSpCas9	negative selection	11634037
201760928	201760951	2	+	28162770	HEL	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.15664082778107613	[429]	[306]	1	hSpCas9	negative selection	11634038
201760873	201760896	2	+	28162770	HEL	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	2.1728528557258935	[276]	[799]	9	hSpCas9	negative selection	11634039
201768865	201768888	2	-	28162770	MV411	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.11713488151308082	[102]	[79]	-1	hSpCas9	negative selection	11803396
201767358	201767381	2	-	28162770	MV411	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.09071204709532216	[203]	[182]	0	hSpCas9	negative selection	11803397
201767285	201767308	2	-	28162770	MV411	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	1.9319357250548461	[27]	[89]	9	hSpCas9	negative selection	11803398
201761157	201761180	2	+	28162770	MV411	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.051220764781739814	[245]	[199]	0	hSpCas9	negative selection	11803399
201761776	201761799	2	-	28162770	MV411	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-2.384830664716737	[30]	[4]	-8	hSpCas9	negative selection	11803400
201761541	201761564	2	+	28162770	MV411	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	1.520785465225076	[150]	[364]	9	hSpCas9	negative selection	11803401
201761368	201761391	2	-	28162770	MV411	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.8646764545276878	[220]	[338]	7	hSpCas9	negative selection	11803402
201761339	201761362	2	+	28162770	MV411	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-1.267135622046983	[99]	[34]	-7	hSpCas9	negative selection	11803403
201760928	201760951	2	+	28162770	MV411	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.4601248718558901	[276]	[320]	4	hSpCas9	negative selection	11803404
201760873	201760896	2	+	28162770	MV411	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.8022643335306129	[257]	[378]	7	hSpCas9	negative selection	11803405
201768865	201768888	2	-	28162770	MONOMAC1	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	2.3488095233952166	[80]	[472]	9	hSpCas9	negative selection	11972762
201767358	201767381	2	-	28162770	MONOMAC1	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.6424479953819165	[127]	[93]	-5	hSpCas9	negative selection	11972763
201767285	201767308	2	-	28162770	MONOMAC1	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-1.2514846310819303	[26]	[12]	-7	hSpCas9	negative selection	11972764
201761157	201761180	2	+	28162770	MONOMAC1	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.3386979962831448	[138]	[125]	-3	hSpCas9	negative selection	11972765
201761776	201761799	2	-	28162770	MONOMAC1	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-1.4449643605031395	[18]	[7]	-8	hSpCas9	negative selection	11972766
201761541	201761564	2	+	28162770	MONOMAC1	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.6982309900881121	[91]	[64]	-5	hSpCas9	negative selection	11972767
201761368	201761391	2	-	28162770	MONOMAC1	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.7390909697740613	[126]	[242]	7	hSpCas9	negative selection	11972768
201761339	201761362	2	+	28162770	MONOMAC1	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.4315021006965766	[79]	[67]	-4	hSpCas9	negative selection	11972769
201760928	201760951	2	+	28162770	MONOMAC1	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.14428549862111506	[265]	[336]	1	hSpCas9	negative selection	11972770
201760873	201760896	2	+	28162770	MONOMAC1	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.18590702250943672	[124]	[162]	2	hSpCas9	negative selection	11972771
201768865	201768888	2	-	28162770	OCIAML2	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	-0.09211820198843151	[24]	[129]	-1	hSpCas9	negative selection	12142128
201767358	201767381	2	-	28162770	OCIAML2	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	0.7084261879522795	[34]	[316]	7	hSpCas9	negative selection	12142129
201767285	201767308	2	-	28162770	OCIAML2	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-1.03005723385618	[6]	[18]	-6	hSpCas9	negative selection	12142130
201761157	201761180	2	+	28162770	OCIAML2	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	-0.5091039730567969	[37]	[147]	-4	hSpCas9	negative selection	12142131
201761776	201761799	2	-	28162770	OCIAML2	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-1.190521906049426	[6]	[16]	-7	hSpCas9	negative selection	12142132
201761541	201761564	2	+	28162770	OCIAML2	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	0.4449779874674664	[32]	[248]	4	hSpCas9	negative selection	12142133
201761368	201761391	2	-	28162770	OCIAML2	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.48356648514471395	[43]	[340]	5	hSpCas9	negative selection	12142134
201761339	201761362	2	+	28162770	OCIAML2	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-0.10805974585745304	[13]	[71]	-1	hSpCas9	negative selection	12142135
201760928	201760951	2	+	28162770	OCIAML2	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	-0.6368467779069119	[84]	[302]	-5	hSpCas9	negative selection	12142136
201760873	201760896	2	+	28162770	OCIAML2	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.630908201219901	[35]	[308]	6	hSpCas9	negative selection	12142137
201768865	201768888	2	-	28162770	OCIAML3	viability	CGATGGACTCAAAGAAGAGAAGG	ALS2	ENSG00000003393	0.23606735823352443	[26]	[95]	2	hSpCas9	negative selection	12311494
201767358	201767381	2	-	28162770	OCIAML3	viability	AACAGAGGCAGAAGGATCCAAGG	ALS2	ENSG00000003393	-0.5028597522659678	[68]	[146]	-4	hSpCas9	negative selection	12311495
201767285	201767308	2	-	28162770	OCIAML3	viability	GAGAGATTGCCAGGCTGGGGAGG	ALS2	ENSG00000003393	-0.07943446749440497	[6]	[19]	0	hSpCas9	negative selection	12311496
201761157	201761180	2	+	28162770	OCIAML3	viability	GGAGGGGCTGAGAGCAGTGCTGG	ALS2	ENSG00000003393	0.620436027896794	[77]	[361]	5	hSpCas9	negative selection	12311497
201761776	201761799	2	-	28162770	OCIAML3	viability	GGGACTCTTCCCTGGAGAAGTGG	ALS2	ENSG00000003393	-0.009045139603006902	[13]	[41]	0	hSpCas9	negative selection	12311498
201761541	201761564	2	+	28162770	OCIAML3	viability	CCTGACTGCTAACAAAGGGCTGG	ALS2	ENSG00000003393	-0.7460107337692131	[54]	[98]	-5	hSpCas9	negative selection	12311499
201761368	201761391	2	-	28162770	OCIAML3	viability	GTGGTGCTTCAAGTTGCCTGTGG	ALS2	ENSG00000003393	0.6605651867614346	[56]	[271]	6	hSpCas9	negative selection	12311500
201761339	201761362	2	+	28162770	OCIAML3	viability	ATTGTACAAGGGCTAAGCTGTGG	ALS2	ENSG00000003393	-1.1268816298968651	[33]	[46]	-7	hSpCas9	negative selection	12311501
201760928	201760951	2	+	28162770	OCIAML3	viability	AATGATCTGACAGTTTCCGTAGG	ALS2	ENSG00000003393	0.6836311784184025	[85]	[416]	6	hSpCas9	negative selection	12311502
201760873	201760896	2	+	28162770	OCIAML3	viability	GCAGGTACCTGAGATGGCACTGG	ALS2	ENSG00000003393	0.7940096450209717	[63]	[334]	7	hSpCas9	negative selection	12311503