Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8546
• Symbol: AP3B1
• Description: adaptor related protein complex 3 subunit beta 1

DataSource: http://genomecrispr.dkfz.de/#!/results/AP3B1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
78294531	78294554	5	-	26472758	Jiyoye	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.20386777268537726	[306]	[200]	-1	hSpCas9	negative selection	7797
78162834	78162857	5	+	26472758	Jiyoye	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.6229266502835458	[338]	[165]	-4	hSpCas9	negative selection	7798
78181506	78181529	5	-	26472758	Jiyoye	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.6661515707653137	[177]	[212]	5	hSpCas9	negative selection	7799
78128074	78128097	5	-	26472758	Jiyoye	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	2.8743013919331717	[16]	[93]	9	hSpCas9	negative selection	7800
78113758	78113781	5	-	26472758	Jiyoye	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	1.6363093807213764	[60]	[142]	8	hSpCas9	negative selection	7801
78294460	78294483	5	+	26472758	Jiyoye	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.7905040210573789	[114]	[149]	5	hSpCas9	negative selection	7802
78129123	78129146	5	+	26472758	Jiyoye	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	4.162062883669342	[3]	[53]	9	hSpCas9	negative selection	7803
78113876	78113899	5	-	26472758	Jiyoye	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-1.7992754959615531	[59]	[12]	-8	hSpCas9	negative selection	7804
78015463	78015486	5	+	26472758	Jiyoye	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-1.3171901758806992	[151]	[45]	-7	hSpCas9	negative selection	7805
78267529	78267552	5	-	26472758	Jiyoye	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	4.107615099646965	[0]	[12]	9	hSpCas9	negative selection	7806
78294531	78294554	5	-	26472758	KBM7	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.6054001193929515	[830,569]	[214,211]	-5	hSpCas9	negative selection	198915
78162834	78162857	5	+	26472758	KBM7	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.03424536349043761	[950,1024]	[436,475]	0	hSpCas9	negative selection	198916
78181506	78181529	5	-	26472758	KBM7	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.29475069030777734	[799,671]	[356,212]	-3	hSpCas9	negative selection	198917
78128074	78128097	5	-	26472758	KBM7	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.188980569786671	[499,264]	[150,242]	2	hSpCas9	negative selection	198918
78113758	78113781	5	-	26472758	KBM7	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.23950339533755594	[306,206]	[177,106]	2	hSpCas9	negative selection	198919
78294460	78294483	5	+	26472758	KBM7	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.04121617119840543	[507,311]	[151,211]	0	hSpCas9	negative selection	198920
78129123	78129146	5	+	26472758	KBM7	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.15443565590154967	[340,351]	[172,190]	1	hSpCas9	negative selection	198921
78113876	78113899	5	-	26472758	KBM7	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.7079607138254691	[281,148]	[24,91]	-5	hSpCas9	negative selection	198922
78015463	78015486	5	+	26472758	KBM7	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.15652700102725153	[367,469]	[239,125]	-1	hSpCas9	negative selection	198923
78267529	78267552	5	-	26472758	KBM7	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-1.037436901476339	[125,95]	[11,36]	-7	hSpCas9	negative selection	198924
78294531	78294554	5	-	26472758	Raji	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.41366720152736375	[286]	[49]	-3	hSpCas9	negative selection	390033
78162834	78162857	5	+	26472758	Raji	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.36271500831555403	[542]	[97]	-3	hSpCas9	negative selection	390034
78181506	78181529	5	-	26472758	Raji	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.39895734742131983	[316]	[96]	4	hSpCas9	negative selection	390035
78128074	78128097	5	-	26472758	Raji	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.39785177287682266	[175]	[30]	-3	hSpCas9	negative selection	390036
78113758	78113781	5	-	26472758	Raji	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.734829367416269	[144]	[55]	7	hSpCas9	negative selection	390037
78294460	78294483	5	+	26472758	Raji	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.8059195430459529	[174]	[70]	7	hSpCas9	negative selection	390038
78129123	78129146	5	+	26472758	Raji	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.23902754118407044	[156]	[42]	2	hSpCas9	negative selection	390039
78113876	78113899	5	-	26472758	Raji	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	0.014274130982117939	[63]	[14]	0	hSpCas9	negative selection	390040
78015463	78015486	5	+	26472758	Raji	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.29202331219148026	[152]	[28]	-2	hSpCas9	negative selection	390041
78267529	78267552	5	-	26472758	Raji	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.25518654401110874	[71]	[13]	-2	hSpCas9	negative selection	390042
78294531	78294554	5	-	26472758	K562	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.4569856812768145	[747]	[459]	-3	hSpCas9	negative selection	581151
78162834	78162857	5	+	26472758	K562	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.7828732697632316	[682]	[991]	6	hSpCas9	negative selection	581152
78181506	78181529	5	-	26472758	K562	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.17936817833469765	[498]	[476]	1	hSpCas9	negative selection	581153
78128074	78128097	5	-	26472758	K562	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.43694825700777196	[262]	[163]	-3	hSpCas9	negative selection	581154
78113758	78113781	5	-	26472758	K562	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.8484900513353076	[174]	[265]	7	hSpCas9	negative selection	581155
78294460	78294483	5	+	26472758	K562	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	1.0145511857678524	[257]	[439]	8	hSpCas9	negative selection	581156
78129123	78129146	5	+	26472758	K562	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	1.5066920176604355	[315]	[757]	9	hSpCas9	negative selection	581157
78113876	78113899	5	-	26472758	K562	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.0388880731936081	[128]	[105]	0	hSpCas9	negative selection	581158
78015463	78015486	5	+	26472758	K562	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.3612323926491969	[248]	[269]	3	hSpCas9	negative selection	581159
78267529	78267552	5	-	26472758	K562	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.9526181193931067	[93]	[40]	-5	hSpCas9	negative selection	581160
78089460	78089483	5	+	26627737	DLD1	viability	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	1.0768965324404038	[278]	[244,171,140]	8	hSpCas9	negative selection	829533
78128125	78128148	5	+	26627737	DLD1	viability	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.4710068263985173	[177]	[89,64,75]	5	hSpCas9	negative selection	829534
78228188	78228211	5	-	26627737	DLD1	viability	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.0614064242184837	[137]	[135,82,55]	8	hSpCas9	negative selection	829535
78294460	78294483	5	+	26627737	DLD1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	1.3501830659268212	[78]	[62,115,18]	9	hSpCas9	negative selection	829536
78294535	78294558	5	-	26627737	DLD1	viability	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.919469803886767	[371]	[262,268,141]	8	hSpCas9	negative selection	829537
78089460	78089483	5	+	26627737	GBM cells	viability after 5 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.33187328216179157	[19]	[6,19]	5	hSpCas9	negative selection	911848
78128125	78128148	5	+	26627737	GBM cells	viability after 5 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.08015418955583209	[126]	[42,100]	1	hSpCas9	negative selection	911849
78228188	78228211	5	-	26627737	GBM cells	viability after 5 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.3374868886253183	[151]	[95,109]	5	hSpCas9	negative selection	911850
78294460	78294483	5	+	26627737	GBM cells	viability after 5 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.9443606214268612	[60]	[20,12]	-9	hSpCas9	negative selection	911851
78294535	78294558	5	-	26627737	GBM cells	viability after 5 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.5533832429622405	[352]	[126,130]	-7	hSpCas9	negative selection	911852
78089460	78089483	5	+	26627737	GBM cells	viability after 13 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.6650050019115126	[19]	[14,18]	7	hSpCas9	negative selection	994163
78128125	78128148	5	+	26627737	GBM cells	viability after 13 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.16171961810318136	[126]	[102,55]	2	hSpCas9	negative selection	994164
78228188	78228211	5	-	26627737	GBM cells	viability after 13 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.41755907709638973	[151]	[145,80]	5	hSpCas9	negative selection	994165
78294460	78294483	5	+	26627737	GBM cells	viability after 13 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.2060989926257517	[60]	[15,12]	-8	hSpCas9	negative selection	994166
78294535	78294558	5	-	26627737	GBM cells	viability after 13 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.28673293517454435	[352]	[172,143]	-3	hSpCas9	negative selection	994167
78089460	78089483	5	+	26627737	GBM cells	viability after 21 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.6200814023149861	[19]	[11,20]	6	hSpCas9	negative selection	1076478
78128125	78128148	5	+	26627737	GBM cells	viability after 21 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.6051833366643833	[126]	[105,103]	6	hSpCas9	negative selection	1076479
78228188	78228211	5	-	26627737	GBM cells	viability after 21 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.07042126373237134	[151]	[86,70]	0	hSpCas9	negative selection	1076480
78294460	78294483	5	+	26627737	GBM cells	viability after 21 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.1564947336354416	[60]	[17,11]	-7	hSpCas9	negative selection	1076481
78294535	78294558	5	-	26627737	GBM cells	viability after 21 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.7334863654729619	[352]	[118,111]	-6	hSpCas9	negative selection	1076482
78089460	78089483	5	+	26627737	RPE1	viability after 9 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	-0.6657206217366385	[1008]	[199,197]	-5	hSpCas9	negative selection	1158793
78128125	78128148	5	+	26627737	RPE1	viability after 9 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.26461375887217764	[500]	[68,209]	-2	hSpCas9	negative selection	1158794
78228188	78228211	5	-	26627737	RPE1	viability after 9 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.8940503227070695	[434]	[232,278]	6	hSpCas9	negative selection	1158795
78294460	78294483	5	+	26627737	RPE1	viability after 9 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.3414789089484325	[476]	[54,63]	-7	hSpCas9	negative selection	1158796
78294535	78294558	5	-	26627737	RPE1	viability after 9 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.6989069000386053	[1215]	[213,260]	-5	hSpCas9	negative selection	1158797
78089460	78089483	5	+	26627737	RPE1	viability after 12 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	-0.412600442856264	[1008]	[191,215]	-3	hSpCas9	negative selection	1241108
78128125	78128148	5	+	26627737	RPE1	viability after 12 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.16120619790478274	[500]	[64,178]	-1	hSpCas9	negative selection	1241109
78228188	78228211	5	-	26627737	RPE1	viability after 12 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.9506890438116942	[434]	[187,265]	6	hSpCas9	negative selection	1241110
78294460	78294483	5	+	26627737	RPE1	viability after 12 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.02805717536721608	[476]	[97,154]	0	hSpCas9	negative selection	1241111
78294535	78294558	5	-	26627737	RPE1	viability after 12 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.22091464138923828	[1215]	[307,250]	-1	hSpCas9	negative selection	1241112
78089460	78089483	5	+	26627737	RPE1	viability after 15 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.002407507834454259	[1008]	[403,171]	0	hSpCas9	negative selection	1323423
78128125	78128148	5	+	26627737	RPE1	viability after 15 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.13240378184176205	[500]	[135,173]	0	hSpCas9	negative selection	1323424
78228188	78228211	5	-	26627737	RPE1	viability after 15 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.8128976792378522	[434]	[290,143]	5	hSpCas9	negative selection	1323425
78294460	78294483	5	+	26627737	RPE1	viability after 15 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.6916107011902012	[476]	[80,85]	-4	hSpCas9	negative selection	1323426
78294535	78294558	5	-	26627737	RPE1	viability after 15 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.0443652187721717	[1215]	[285,420]	0	hSpCas9	negative selection	1323427
78089460	78089483	5	+	26627737	RPE1	viability after 18 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.45909489234634693	[1008]	[441,301]	3	hSpCas9	negative selection	1405738
78128125	78128148	5	+	26627737	RPE1	viability after 18 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.10862680528804536	[500]	[136,112]	0	hSpCas9	negative selection	1405739
78228188	78228211	5	-	26627737	RPE1	viability after 18 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.3623861220067251	[434]	[162,137]	2	hSpCas9	negative selection	1405740
78294460	78294483	5	+	26627737	RPE1	viability after 18 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.587009745976252	[476]	[52,31]	-7	hSpCas9	negative selection	1405741
78294535	78294558	5	-	26627737	RPE1	viability after 18 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.11010684238818014	[1215]	[319,286]	0	hSpCas9	negative selection	1405742
78089460	78089483	5	+	26627737	HeLa	viability after 8 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.7492334773202675	[236]	[87,250,162]	6	hSpCas9	negative selection	1488053
78128125	78128148	5	+	26627737	HeLa	viability after 8 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	7.204226020432306	[1]	[172,95,125]	9	hSpCas9	negative selection	1488054
78228188	78228211	5	-	26627737	HeLa	viability after 8 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.23713885930006495	[406]	[165,178,111]	-2	hSpCas9	negative selection	1488055
78294460	78294483	5	+	26627737	HeLa	viability after 8 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.25952584637390697	[115]	[0,52,61]	-2	hSpCas9	negative selection	1488056
78294535	78294558	5	-	26627737	HeLa	viability after 8 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.1848861463052299	[444]	[335,146,203]	1	hSpCas9	negative selection	1488057
78089460	78089483	5	+	26627737	HeLa	viability after 12 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.05571653888145933	[236]	[95,103,104]	0	hSpCas9	negative selection	1570368
78128125	78128148	5	+	26627737	HeLa	viability after 12 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	7.205755124235517	[1]	[128,95,143]	9	hSpCas9	negative selection	1570369
78228188	78228211	5	-	26627737	HeLa	viability after 12 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.01956120586382481	[406]	[161,134,217]	0	hSpCas9	negative selection	1570370
78294460	78294483	5	+	26627737	HeLa	viability after 12 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.1200690906578945	[115]	[102,49,4]	1	hSpCas9	negative selection	1570371
78294535	78294558	5	-	26627737	HeLa	viability after 12 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.17893366561928478	[444]	[297,105,233]	1	hSpCas9	negative selection	1570372
78089460	78089483	5	+	26627737	HeLa	viability after 15 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.24388285359374423	[236]	[69,150,122]	2	hSpCas9	negative selection	1652683
78128125	78128148	5	+	26627737	HeLa	viability after 15 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	7.007858100115601	[1]	[73,120,120]	9	hSpCas9	negative selection	1652684
78228188	78228211	5	-	26627737	HeLa	viability after 15 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.11638263704782428	[406]	[100,207,149]	-1	hSpCas9	negative selection	1652685
78294460	78294483	5	+	26627737	HeLa	viability after 15 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.7031807055824433	[115]	[115,26,87]	5	hSpCas9	negative selection	1652686
78294535	78294558	5	-	26627737	HeLa	viability after 15 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.6162969693946261	[444]	[83,67,209]	-5	hSpCas9	negative selection	1652687
78089460	78089483	5	+	26627737	HeLa	viability after 18 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.267108667341051	[236]	[48,126,122]	2	hSpCas9	negative selection	1734998
78128125	78128148	5	+	26627737	HeLa	viability after 18 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	6.948585697080799	[1]	[47,91,120]	9	hSpCas9	negative selection	1734999
78228188	78228211	5	-	26627737	HeLa	viability after 18 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.104548662666158	[406]	[67,174,149]	-1	hSpCas9	negative selection	1735000
78294460	78294483	5	+	26627737	HeLa	viability after 18 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.7345025373633087	[115]	[78,24,87]	6	hSpCas9	negative selection	1735001
78294535	78294558	5	-	26627737	HeLa	viability after 18 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.6238849182084198	[444]	[52,58,209]	-5	hSpCas9	negative selection	1735002
78089460	78089483	5	+	26627737	HCT116	viability after 6 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	-1.2174555143654775	[558]	[89,8]	-6	hSpCas9	negative selection	1817313
78128125	78128148	5	+	26627737	HCT116	viability after 6 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	1.2109730791413327	[320]	[266,33]	6	hSpCas9	negative selection	1817314
78228188	78228211	5	-	26627737	HCT116	viability after 6 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.877794463567902	[271]	[1,34]	-5	hSpCas9	negative selection	1817315
78294460	78294483	5	+	26627737	HCT116	viability after 6 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.9535827022224304	[82]	[3,36]	5	hSpCas9	negative selection	1817316
78294535	78294558	5	-	26627737	HCT116	viability after 6 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.9585802493546174	[452]	[35,36]	-5	hSpCas9	negative selection	1817317
78089460	78089483	5	+	26627737	HCT116	viability after 8 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.9838242489219602	[112]	[111,114,141]	8	hSpCas9	negative selection	1899628
78128125	78128148	5	+	26627737	HCT116	viability after 8 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-1.3426902890771886	[191]	[24,70,28]	-9	hSpCas9	negative selection	1899629
78228188	78228211	5	-	26627737	HCT116	viability after 8 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.6515930269502791	[176]	[116,106,233]	6	hSpCas9	negative selection	1899630
78294460	78294483	5	+	26627737	HCT116	viability after 8 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.8016839496228134	[154]	[45,56,43]	-7	hSpCas9	negative selection	1899631
78294535	78294558	5	-	26627737	HCT116	viability after 8 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.23433815888929338	[240]	[184,113,169]	2	hSpCas9	negative selection	1899632
78089460	78089483	5	+	26627737	HCT116	viability after 9 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.17631641248343244	[558]	[23,282]	1	hSpCas9	negative selection	1981943
78128125	78128148	5	+	26627737	HCT116	viability after 9 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-1.9780480683958053	[320]	[4,34]	-8	hSpCas9	negative selection	1981944
78228188	78228211	5	-	26627737	HCT116	viability after 9 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.3592689422251634	[271]	[268,120]	8	hSpCas9	negative selection	1981945
78294460	78294483	5	+	26627737	HCT116	viability after 9 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	1.5400689166516632	[82]	[21,97]	8	hSpCas9	negative selection	1981946
78294535	78294558	5	-	26627737	HCT116	viability after 9 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	1.0928498267304876	[452]	[195,306]	7	hSpCas9	negative selection	1981947
78089460	78089483	5	+	26627737	HCT116	viability after 12 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	1.5409321039129242	[112]	[233,171,106]	9	hSpCas9	negative selection	2064258
78128125	78128148	5	+	26627737	HCT116	viability after 12 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-1.8269842712678201	[191]	[19,25,39]	-9	hSpCas9	negative selection	2064259
78228188	78228211	5	-	26627737	HCT116	viability after 12 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.739391869336382	[176]	[124,91,249]	6	hSpCas9	negative selection	2064260
78294460	78294483	5	+	26627737	HCT116	viability after 12 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.9237154098633484	[154]	[15,25,22]	-9	hSpCas9	negative selection	2064261
78294535	78294558	5	-	26627737	HCT116	viability after 12 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.6502878585119642	[240]	[179,281,137]	6	hSpCas9	negative selection	2064262
78089460	78089483	5	+	26627737	HCT116	viability after 15 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.504078404339419	[112]	[112,101,63]	5	hSpCas9	negative selection	2146573
78128125	78128148	5	+	26627737	HCT116	viability after 15 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-2.156683274368138	[191]	[15,21,34]	-9	hSpCas9	negative selection	2146574
78228188	78228211	5	-	26627737	HCT116	viability after 15 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.2196051443910303	[176]	[285,178,250]	8	hSpCas9	negative selection	2146575
78294460	78294483	5	+	26627737	HCT116	viability after 15 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.011534843163965	[154]	[60,69,3]	-7	hSpCas9	negative selection	2146576
78294535	78294558	5	-	26627737	HCT116	viability after 15 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.5898312865566395	[240]	[175,236,207]	5	hSpCas9	negative selection	2146577
78089460	78089483	5	+	26627737	HCT116	viability after 18 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.5663260114679912	[112]	[85,135,13]	5	hSpCas9	negative selection	2228888
78128125	78128148	5	+	26627737	HCT116	viability after 18 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-1.9218012161891527	[191]	[9,8,56]	-9	hSpCas9	negative selection	2228889
78228188	78228211	5	-	26627737	HCT116	viability after 18 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.4072224975075858	[176]	[385,151,143]	8	hSpCas9	negative selection	2228890
78294460	78294483	5	+	26627737	HCT116	viability after 18 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-1.627210250486158	[154]	[40,23,6]	-8	hSpCas9	negative selection	2228891
78294535	78294558	5	-	26627737	HCT116	viability after 18 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.7371548820622122	[240]	[253,157,171]	6	hSpCas9	negative selection	2228892
78092925	78092948	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCATGCCAAG	AP3B1	ENSG00000132842	0.3888402363631881	[40,30]	[14,4]	1	dCas9-VP64	positive selection	2384317
78009343	78009366	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTCAGCCTCCTGAGTAGCTAG	AP3B1	ENSG00000132842	-0.29935217365489764	[71,81]	[9,16]	-1	dCas9-VP64	positive selection	2389845
78024733	78024756	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGTATTTTAGTAGAGACGAGG	AP3B1	ENSG00000132842	3.172977660691175	[5,24]	[15,48]	8	dCas9-VP64	positive selection	2389988
78152113	78152136	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGGGAGAGGGAGAAGGAGAG	AP3B1	ENSG00000132842	0.49591073393401697	[0,5]	[0,0]	2	dCas9-VP64	positive selection	2403261
78147987	78148010	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCAGG	AP3B1	ENSG00000132842	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416266
78285052	78285075	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCGTGTTAGCCGGG	AP3B1	ENSG00000132842	0.853016361217498	[78,47]	[31,16]	3	dCas9-VP64	positive selection	2418340
78237736	78237759	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTGCCGG	AP3B1	ENSG00000132842	2.0086676745603276	[0,0]	[0,0]	7	dCas9-VP64	positive selection	2421638
78184073	78184096	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGACTCACTTGAACCCTGG	AP3B1	ENSG00000132842	0.500195564350366	[42,188]	[9,64]	2	dCas9-VP64	positive selection	2426414
78167940	78167963	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGGTGATTTCTGAGATTTCGG	AP3B1	ENSG00000132842	1.0469029585009717	[317,416]	[49,294]	4	dCas9-VP64	positive selection	2442121
78074793	78074816	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACAAAACTAGCCGGGCGTGGTGG	AP3B1	ENSG00000132842	-0.03799027843330949	[9,1]	[0,0]	0	dCas9-VP64	positive selection	2449467
78275682	78275705	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCTTAG	AP3B1	ENSG00000132842	-2.0034890161781562	[180,449]	[14,19]	-9	dCas9-VP64	positive selection	2449532
78251959	78251982	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGACTTTGTCTTGCATCTTGG	AP3B1	ENSG00000132842	-0.1766347284998866	[510,198]	[63,72]	0	dCas9-VP64	positive selection	2454355
78092925	78092948	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCATGCCAAG	AP3B1	ENSG00000132842	0.501495088189527	[102,55]	[55,18]	4	dCas9-VP64	positive selection	2479572
78009343	78009366	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTCAGCCTCCTGAGTAGCTAG	AP3B1	ENSG00000132842	0.6576184974956476	[246,231]	[69,172]	5	dCas9-VP64	positive selection	2485100
78024733	78024756	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGTATTTTAGTAGAGACGAGG	AP3B1	ENSG00000132842	0.6298554829582325	[47,33]	[33,7]	4	dCas9-VP64	positive selection	2485243
78152113	78152136	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGGGAGAGGGAGAAGGAGAG	AP3B1	ENSG00000132842	0.05733779863415167	[24,2]	[5,2]	0	dCas9-VP64	positive selection	2498516
78147987	78148010	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCAGG	AP3B1	ENSG00000132842	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511521
78285052	78285075	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCGTGTTAGCCGGG	AP3B1	ENSG00000132842	1.9224239682243596	[76,41]	[141,10]	8	dCas9-VP64	positive selection	2513595
78237736	78237759	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTGCCGG	AP3B1	ENSG00000132842	1.7422137968451281	[0,0]	[0,0]	8	dCas9-VP64	positive selection	2516893
78184073	78184096	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGACTCACTTGAACCCTGG	AP3B1	ENSG00000132842	0.20181402276249916	[106,226]	[30,91]	1	dCas9-VP64	positive selection	2521669
78167940	78167963	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGGTGATTTCTGAGATTTCGG	AP3B1	ENSG00000132842	0.9661199072074318	[327,324]	[329,93]	6	dCas9-VP64	positive selection	2537376
78074793	78074816	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACAAAACTAGCCGGGCGTGGTGG	AP3B1	ENSG00000132842	0.017710828982869575	[11,40]	[4,10]	0	dCas9-VP64	positive selection	2544722
78275682	78275705	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCTTAG	AP3B1	ENSG00000132842	2.1771212462212475	[324,289]	[546,370]	8	dCas9-VP64	positive selection	2544787
78251959	78251982	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGACTTTGTCTTGCATCTTGG	AP3B1	ENSG00000132842	1.172522628723105	[386,325]	[427,107]	7	dCas9-VP64	positive selection	2549610
78216142	78216165	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	-0.1509520213165415	[2,2]	[1,1]	-2	hSpCas9	positive selection	2970806
78216085	78216108	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-1.7210868705825215	[2,3]	[0,0]	-9	hSpCas9	positive selection	2970807
78227397	78227420	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	-0.32669666195452773	[3,3]	[2,1]	-5	hSpCas9	positive selection	2970808
78181506	78181529	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.742729352421067	[3,3]	[0,2]	-8	hSpCas9	positive selection	2970809
78216142	78216165	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	-0.07930849197517142	[2,2]	[0,1]	-1	hSpCas9	positive selection	3038664
78216085	78216108	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.6564751277672094	[2,2]	[1,0]	-8	hSpCas9	positive selection	3038665
78227397	78227420	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	-0.817451119680962	[3,3]	[1,0]	-9	hSpCas9	positive selection	3038666
78181506	78181529	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-1.1552986763797801	[3,3]	[1,0]	-9	hSpCas9	positive selection	3038667
78216082	78216105		-	24336571	A375	resistance to PLX after 7 days	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.17724815233418056	[19,14]	[14,15]	-5	hSpCas9	positive selection	3121937
78225579	78225602		+	24336571	A375	resistance to PLX after 7 days	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-0.3452849825127329	[7,7]	[6,5]	-8	hSpCas9	positive selection	3121947
78216084	78216107		+	24336571	A375	resistance to PLX after 7 days	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.05507985537407334	[13,13]	[12,15]	2	hSpCas9	positive selection	3121958
78225589	78225612		-	24336571	A375	resistance to PLX after 7 days	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.02389301171980529	[4,6]	[4,6]	0	hSpCas9	positive selection	3121966
78216082	78216105		-	24336571	A375	resistance to PLX after 14 days	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.5979539932678499	[12,17]	[4,3]	-7	hSpCas9	positive selection	3179730
78225579	78225602		+	24336571	A375	resistance to PLX after 14 days	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-0.23495779667444971	[9,5]	[2,2]	-3	hSpCas9	positive selection	3179740
78216084	78216107		+	24336571	A375	resistance to PLX after 14 days	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.5168180469987402	[15,13]	[9,9]	5	hSpCas9	positive selection	3179751
78225589	78225612		-	24336571	A375	resistance to PLX after 14 days	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.8319111282019994	[2,4]	[2,3]	7	hSpCas9	positive selection	3179759
78216082	78216105		-	24336571	A375	viability after 7 days	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.019019949975340844	[18]	[19,14]	0	hSpCas9	negative selection	3237523
78225579	78225602		+	24336571	A375	viability after 7 days	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-0.43165747089709783	[11]	[7,7]	-6	hSpCas9	negative selection	3237533
78216084	78216107		+	24336571	A375	viability after 7 days	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.1429670128385507	[15]	[13,13]	-2	hSpCas9	negative selection	3237544
78225589	78225612		-	24336571	A375	viability after 7 days	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.13803988233011677	[4]	[4,6]	2	hSpCas9	negative selection	3237552
78216082	78216105		-	24336571	A375	viability after 14 days	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.20948059144034298	[18]	[12,17]	-2	hSpCas9	negative selection	3295316
78225579	78225602		+	24336571	A375	viability after 14 days	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-0.42555274529048015	[11]	[9,5]	-5	hSpCas9	negative selection	3295326
78216084	78216107		+	24336571	A375	viability after 14 days	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.027998697290668728	[15]	[15,13]	0	hSpCas9	negative selection	3295337
78225589	78225612		-	24336571	A375	viability after 14 days	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.22258981354677476	[4]	[2,4]	-3	hSpCas9	negative selection	3295345
78216082	78216105	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.02843863027640673	[161,149]	[0,0]	0	hSpCas9	positive selection	3336898
78216084	78216107	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	2.009646860906601	[36,38]	[0,0]	7	hSpCas9	positive selection	3336899
78181569	78181592	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	4.01287686923619	[5,12]	[0,0]	9	hSpCas9	positive selection	3336900
78181605	78181628	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	0.7442566292064644	[273,273]	[2,2]	3	hSpCas9	positive selection	3356146
78225589	78225612	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.3746831620839938	[117,117]	[0,0]	2	hSpCas9	positive selection	3356147
78225579	78225602	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-1.8327862082184536	[544,544]	[0,0]	-9	hSpCas9	positive selection	3356148
78216141	78216164	5	+	26780180	HT29	viability (Avana library 4 designs)	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	3.2104245010735	[]	[]	8	hSpCas9	negative selection	3406902
78216084	78216107	5	+	26780180	HT29	viability (Avana library 4 designs)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	3.28114203711826	[]	[]	8	hSpCas9	negative selection	3406903
78227396	78227419	5	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	3.40588789020492	[]	[]	8	hSpCas9	negative selection	3406904
78181506	78181529	5	-	26780180	HT29	viability (Avana library 4 designs)	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	2.35898905641041	[]	[]	8	hSpCas9	negative selection	3406905
78181506	78181529	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-2.59535447515593	[]	[]	-3	hSpCas9	negative selection	3479694
78216084	78216107	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.214047160790666	[]	[]	0	hSpCas9	negative selection	3479695
78227396	78227419	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	-5.38020656434599	[]	[]	-5	hSpCas9	negative selection	3479696
78216141	78216164	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	-3.73938247997454	[]	[]	-4	hSpCas9	negative selection	3479697
78216121	78216144	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTGGATGTTGAAGAGTGGGGG	AP3B1	ENSG00000132842	-2.47587775993298	[]	[]	-3	hSpCas9	negative selection	3479698
78162933	78162956	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGACCTATGTGAAAAGCCAGG	AP3B1	ENSG00000132842	-0.557088149263891	[]	[]	0	hSpCas9	negative selection	3479699
78181506	78181529	5	-	26780180	A375	viability (Avana lentiGuide)	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	6.76899500203025	[]	[]	5	hSpCas9	negative selection	3588353
78216084	78216107	5	+	26780180	A375	viability (Avana lentiGuide)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	11.2647340130672	[]	[]	7	hSpCas9	negative selection	3588354
78227396	78227419	5	+	26780180	A375	viability (Avana lentiGuide)	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	0.767531196823886	[]	[]	0	hSpCas9	negative selection	3588355
78216141	78216164	5	+	26780180	A375	viability (Avana lentiGuide)	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	10.7264823262169	[]	[]	7	hSpCas9	negative selection	3588356
78216121	78216144	5	-	26780180	A375	viability (Avana lentiGuide)	TAGTGGATGTTGAAGAGTGGGGG	AP3B1	ENSG00000132842	5.37778904204681	[]	[]	5	hSpCas9	negative selection	3588357
78162933	78162956	5	-	26780180	A375	viability (Avana lentiGuide)	TTAGACCTATGTGAAAAGCCAGG	AP3B1	ENSG00000132842	2.79264898447592	[]	[]	3	hSpCas9	negative selection	3588358
78181506	78181529	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.0057470580610395686	[5]	[5,4]	0	hSpCas9	positive selection	3697012
78216084	78216107	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.12053129368701228	[5]	[6,5]	3	hSpCas9	positive selection	3697013
78227396	78227419	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	-0.6538245308576375	[5]	[2,3]	-7	hSpCas9	positive selection	3697014
78216141	78216164	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	-0.08903564166609845	[6]	[5,5]	-1	hSpCas9	positive selection	3697015
78216121	78216144	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTGGATGTTGAAGAGTGGGGG	AP3B1	ENSG00000132842	-0.1473779228081695	[4]	[4,3]	-2	hSpCas9	positive selection	3697016
78162933	78162956	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGACCTATGTGAAAAGCCAGG	AP3B1	ENSG00000132842	-0.009419728856105813	[5]	[5,5]	0	hSpCas9	positive selection	3697017
78181506	78181529	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.008233299225962915	[5]	[4,4]	0	hSpCas9	positive selection	3805619
78216084	78216107	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.7090051196218724	[5]	[1,2]	-7	hSpCas9	positive selection	3805620
78227396	78227419	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCATTCTTCCTAACATATGG	AP3B1	ENSG00000132842	0.3794027097587712	[5]	[6,6]	9	hSpCas9	positive selection	3805621
78216141	78216164	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGTAAGTTACATAGCTTGCGG	AP3B1	ENSG00000132842	-0.3336408161150495	[4]	[4,1]	-4	hSpCas9	positive selection	3805622
78216121	78216144	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTGGATGTTGAAGAGTGGGGG	AP3B1	ENSG00000132842	0.13552476429798033	[5]	[5,4]	3	hSpCas9	positive selection	3805623
78162933	78162956	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGACCTATGTGAAAAGCCAGG	AP3B1	ENSG00000132842	-0.014294496173724427	[5]	[4,5]	0	hSpCas9	positive selection	3805624
78181569	78181592	5	-	26780180	A375	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.800698544308954	[]	[]	3	hSpCas9	negative selection	3913847
78216082	78216105	5	-	26780180	A375	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	1.14898474140939	[]	[]	6	hSpCas9	negative selection	3913848
78225579	78225602	5	+	26780180	A375	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.978511636394203	[]	[]	4	hSpCas9	negative selection	3913849
78181605	78181628	5	-	26780180	A375	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	1.28344512098006	[]	[]	7	hSpCas9	negative selection	3913850
78216084	78216107	5	+	26780180	A375	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	1.18904739740061	[]	[]	6	hSpCas9	negative selection	3913851
78225589	78225612	5	-	26780180	A375	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.950514136260094	[]	[]	4	hSpCas9	negative selection	3913852
78181569	78181592	5	-	26780180	HT29	viability (GeCKOv2 library)	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.815729357880167	[]	[]	3	hSpCas9	negative selection	4021813
78216082	78216105	5	-	26780180	HT29	viability (GeCKOv2 library)	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	1.76756726396851	[]	[]	8	hSpCas9	negative selection	4021814
78225579	78225602	5	+	26780180	HT29	viability (GeCKOv2 library)	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.440860163167627	[]	[]	1	hSpCas9	negative selection	4021815
78181605	78181628	5	-	26780180	HT29	viability (GeCKOv2 library)	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	0.847061973261775	[]	[]	3	hSpCas9	negative selection	4021816
78216084	78216107	5	+	26780180	HT29	viability (GeCKOv2 library)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	1.32189233658291	[]	[]	6	hSpCas9	negative selection	4021817
78225589	78225612	5	-	26780180	HT29	viability (GeCKOv2 library)	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	1.72296327691579	[]	[]	8	hSpCas9	negative selection	4021818
78216082	78216105	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.23703691505184582	[3]	[1,1]	-5	hSpCas9	positive selection	4145665
78225579	78225602	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	-0.0023297978364298366	[3]	[2,1]	0	hSpCas9	positive selection	4145676
78216084	78216107	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.16449309291505604	[3]	[2,3]	4	hSpCas9	positive selection	4145687
78225589	78225612	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.0470998014343077	[2]	[1,1]	-1	hSpCas9	positive selection	4145698
78216082	78216105	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.3542651657920976	[4]	[4,4,4,0]	2	hSpCas9	positive selection	4209687
78225579	78225602	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.1626720243118435	[3]	[2,3,1,0]	1	hSpCas9	positive selection	4209698
78216084	78216107	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5987630299611588	[4]	[2,0,0,0]	-8	hSpCas9	positive selection	4209709
78225589	78225612	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.7589995232941791	[1]	[0,0,3,0]	5	hSpCas9	positive selection	4209720
78216082	78216105	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.018790354591982805	[3]	[3,2]	0	hSpCas9	positive selection	4256021
78216084	78216107	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.7526428605302079	[1]	[0,0]	-9	hSpCas9	positive selection	4256022
78181569	78181592	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.883854120784768	[1]	[0,0]	-9	hSpCas9	positive selection	4256023
78181605	78181628	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.3168910525638087	[4]	[4,0]	-6	hSpCas9	positive selection	4320305
78225589	78225612	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.3839865378054719	[2]	[2,3]	7	hSpCas9	positive selection	4320306
78225579	78225602	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.24873061415745062	[4]	[3,3]	5	hSpCas9	positive selection	4320307
78141295	78141317	5	+	27760321	OCIAML3	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.6989210518017955	[250,236]	[98,141]	-6	hSpCas9	negative selection	4378485
78162893	78162915	5	+	27760321	OCIAML3	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-0.7167337552887023	[161,118]	[80,46]	-6	hSpCas9	negative selection	4378486
78175680	78175702	5	+	27760321	OCIAML3	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	0.04513172416739364	[113,97]	[73,99]	0	hSpCas9	negative selection	4378487
78177338	78177360	5	-	27760321	OCIAML3	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	0.6484358277172597	[317,355]	[418,412]	7	hSpCas9	negative selection	4378488
78228156	78228178	5	+	27760321	OCIAML3	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.0852358530872686	[398,378]	[110,185]	-7	hSpCas9	negative selection	4378489
78141295	78141317	5	+	27760321	OCIAML2	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	0.1950421272216355	[250,236]	[138,340]	2	hSpCas9	negative selection	4461948
78162893	78162915	5	+	27760321	OCIAML2	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.08716892805326304	[161,118]	[91,155]	1	hSpCas9	negative selection	4461949
78175680	78175702	5	+	27760321	OCIAML2	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	1.6741078356546708	[113,97]	[252,298]	9	hSpCas9	negative selection	4461950
78177338	78177360	5	-	27760321	OCIAML2	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	0.10121285869080582	[317,355]	[289,300]	1	hSpCas9	negative selection	4461951
78228156	78228178	5	+	27760321	OCIAML2	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-0.15802476352037392	[398,378]	[186,407]	-2	hSpCas9	negative selection	4461952
78141295	78141317	5	+	27760321	MV411	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.2179223513053542	[250,236]	[102,191]	-1	hSpCas9	negative selection	4545411
78162893	78162915	5	+	27760321	MV411	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.12289017342462216	[161,118]	[127,57]	0	hSpCas9	negative selection	4545412
78175680	78175702	5	+	27760321	MV411	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	0.1267850750392181	[113,97]	[18,161]	0	hSpCas9	negative selection	4545413
78177338	78177360	5	-	27760321	MV411	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	1.070530200999295	[317,355]	[654,193]	7	hSpCas9	negative selection	4545414
78228156	78228178	5	+	27760321	MV411	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-0.07330549398766584	[398,378]	[87,478]	0	hSpCas9	negative selection	4545415
78141295	78141317	5	+	27760321	HL60	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.5612637442378271	[250,236]	[141,127]	-6	hSpCas9	negative selection	4628874
78162893	78162915	5	+	27760321	HL60	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-0.6001109678095666	[161,118]	[91,56]	-6	hSpCas9	negative selection	4628875
78175680	78175702	5	+	27760321	HL60	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-0.39356084173223627	[113,97]	[39,92]	-4	hSpCas9	negative selection	4628876
78177338	78177360	5	-	27760321	HL60	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.1585176478773585	[317,355]	[201,297]	-2	hSpCas9	negative selection	4628877
78228156	78228178	5	+	27760321	HL60	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	0.15712720751989095	[398,378]	[279,433]	2	hSpCas9	negative selection	4628878
78141295	78141317	5	+	27760321	HT1080	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.42707010811826085	[236,184]	[83,38]	-2	hSpCas9	negative selection	4712337
78162893	78162915	5	+	27760321	HT1080	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-5.400223352591345	[118,92]	[0,0]	-8	hSpCas9	negative selection	4712338
78175680	78175702	5	+	27760321	HT1080	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-5.123992925797117	[97,76]	[0,0]	-8	hSpCas9	negative selection	4712339
78177338	78177360	5	-	27760321	HT1080	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.4178240950295833	[355,277]	[168,12]	-2	hSpCas9	negative selection	4712340
78228156	78228178	5	+	27760321	HT1080	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-3.3806373978213693	[378,295]	[10,14]	-7	hSpCas9	negative selection	4712341
78141295	78141317	5	+	27760321	HT29	viability after 7 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.35605377595595944	[236,184]	[293,132,219]	-5	hSpCas9	negative selection	4795800
78162893	78162915	5	+	27760321	HT29	viability after 7 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.30142582610645063	[118,92]	[185,144,174]	4	hSpCas9	negative selection	4795801
78175680	78175702	5	+	27760321	HT29	viability after 7 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	0.4807510870483669	[97,76]	[117,114,229]	7	hSpCas9	negative selection	4795802
78177338	78177360	5	-	27760321	HT29	viability after 7 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.2531480725382008	[355,277]	[312,291,413]	-4	hSpCas9	negative selection	4795803
78228156	78228178	5	+	27760321	HT29	viability after 7 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-0.31442341337631957	[378,295]	[338,325,378]	-4	hSpCas9	negative selection	4795804
78141295	78141317	5	+	27760321	HT29	viability after 25 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-2.4568721118139027	[236,184]	[78,27,19]	-8	hSpCas9	negative selection	4879263
78162893	78162915	5	+	27760321	HT29	viability after 25 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-0.8115235874480871	[118,92]	[72,70,61]	-6	hSpCas9	negative selection	4879264
78175680	78175702	5	+	27760321	HT29	viability after 25 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-0.660446201096597	[97,76]	[92,4,92]	-5	hSpCas9	negative selection	4879265
78177338	78177360	5	-	27760321	HT29	viability after 25 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.723093159381826	[355,277]	[151,310,196]	-6	hSpCas9	negative selection	4879266
78228156	78228178	5	+	27760321	HT29	viability after 25 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-2.312911567639654	[378,295]	[49,93,91]	-8	hSpCas9	negative selection	4879267
78141295	78141317	5	+	27760321	HT29	viability after 22 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-2.228299437030815	[236,184]	[119,16,16]	-8	hSpCas9	negative selection	4962726
78162893	78162915	5	+	27760321	HT29	viability after 22 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-0.7146369115996107	[118,92]	[70,91,60]	-6	hSpCas9	negative selection	4962727
78175680	78175702	5	+	27760321	HT29	viability after 22 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-2.180285820091668	[97,76]	[24,9,31]	-8	hSpCas9	negative selection	4962728
78177338	78177360	5	-	27760321	HT29	viability after 22 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-1.628076646495812	[355,277]	[128,149,75]	-7	hSpCas9	negative selection	4962729
78228156	78228178	5	+	27760321	HT29	viability after 22 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.2108909427788062	[378,295]	[113,239,152]	-7	hSpCas9	negative selection	4962730
78141295	78141317	5	+	27760321	HT29	viability after 19 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-2.8782361349508427	[236,184]	[49,10,38]	-8	hSpCas9	negative selection	5046189
78162893	78162915	5	+	27760321	HT29	viability after 19 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	-0.1853315587994253	[118,92]	[18,194,96]	-2	hSpCas9	negative selection	5046190
78175680	78175702	5	+	27760321	HT29	viability after 19 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-0.4253075841776326	[97,76]	[74,2,142]	-4	hSpCas9	negative selection	5046191
78177338	78177360	5	-	27760321	HT29	viability after 19 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-1.0732226396379998	[355,277]	[53,373,79]	-6	hSpCas9	negative selection	5046192
78228156	78228178	5	+	27760321	HT29	viability after 19 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.6907048657730948	[378,295]	[161,105,95]	-7	hSpCas9	negative selection	5046193
78141295	78141317	5	+	27760321	HT29	viability after 16 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-1.872823269795458	[236,184]	[149,42,8]	-8	hSpCas9	negative selection	5129652
78162893	78162915	5	+	27760321	HT29	viability after 16 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.014195065180493405	[118,92]	[75,202,73]	0	hSpCas9	negative selection	5129653
78175680	78175702	5	+	27760321	HT29	viability after 16 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-1.3982095519007025	[97,76]	[75,3,35]	-7	hSpCas9	negative selection	5129654
78177338	78177360	5	-	27760321	HT29	viability after 16 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.993337695029241	[355,277]	[227,183,126]	-7	hSpCas9	negative selection	5129655
78228156	78228178	5	+	27760321	HT29	viability after 16 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.1217503874478851	[378,295]	[130,193,190]	-7	hSpCas9	negative selection	5129656
78141295	78141317	5	+	27760321	HT29	viability after 13 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-1.3704412269102872	[236,184]	[116,72,93]	-8	hSpCas9	negative selection	5213115
78162893	78162915	5	+	27760321	HT29	viability after 13 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.27559027073716424	[118,92]	[147,190,109]	3	hSpCas9	negative selection	5213116
78175680	78175702	5	+	27760321	HT29	viability after 13 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-0.4574009872287754	[97,76]	[43,70,104]	-5	hSpCas9	negative selection	5213117
78177338	78177360	5	-	27760321	HT29	viability after 13 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.9590777262832353	[355,277]	[206,282,83]	-7	hSpCas9	negative selection	5213118
78228156	78228178	5	+	27760321	HT29	viability after 13 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.296637210689034	[378,295]	[174,175,128]	-8	hSpCas9	negative selection	5213119
78141295	78141317	5	+	27760321	HT29	viability after 10 days	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-1.1108027589732137	[236,184]	[229,114,22]	-8	hSpCas9	negative selection	5296578
78162893	78162915	5	+	27760321	HT29	viability after 10 days	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.17439052964097645	[118,92]	[144,169,133]	2	hSpCas9	negative selection	5296579
78175680	78175702	5	+	27760321	HT29	viability after 10 days	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	-0.7686128398442804	[97,76]	[86,84,21]	-7	hSpCas9	negative selection	5296580
78177338	78177360	5	-	27760321	HT29	viability after 10 days	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	-0.8564096391694513	[355,277]	[226,318,114]	-7	hSpCas9	negative selection	5296581
78228156	78228178	5	+	27760321	HT29	viability after 10 days	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-1.1527470454754976	[378,295]	[84,304,181]	-8	hSpCas9	negative selection	5296582
78141295	78141317	5	+	27760321	MOLM13	viability	GAATACTTGCTCTAGCAACAGG	AP3B1	ENSG00000132842	-0.17900399033807501	[250,236]	[212,43]	-1	hSpCas9	negative selection	5380041
78162893	78162915	5	+	27760321	MOLM13	viability	CTGCCTATAGTCTGAATAGTGG	AP3B1	ENSG00000132842	0.7633236234941209	[161,118]	[256,27]	5	hSpCas9	negative selection	5380042
78175680	78175702	5	+	27760321	MOLM13	viability	ATAAGGTTCAAACATCCCCTGG	AP3B1	ENSG00000132842	0.7846067646717076	[113,97]	[166,47]	5	hSpCas9	negative selection	5380043
78177338	78177360	5	-	27760321	MOLM13	viability	GCGTTTACTTCGTAGCAATAGG	AP3B1	ENSG00000132842	0.15324549471864332	[317,355]	[298,139]	1	hSpCas9	negative selection	5380044
78228156	78228178	5	+	27760321	MOLM13	viability	CTGAAAAGTGCTTATGGACAGG	AP3B1	ENSG00000132842	-0.9705998693526166	[398,378]	[22,187]	-5	hSpCas9	negative selection	5380045
78294299	78294322	5	-	27661255	K562	viability	GTCCCGCGGGTGGGTAGGTGGGG	AP3B1	ENSG00000132842	-0.02545838992744287	[439,553]	[422,358]	-1	dCas9-KRAB	negative selection	5462649
78216082	78216105	5	-	27260156	BXPC3	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.07652911291037212	[919]	[909,834,930,979]	-2	hSpCas9	negative selection	5528481
78216084	78216107	5	+	27260156	BXPC3	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.3738308727829962	[135]	[77,125,85,155]	-7	hSpCas9	negative selection	5528482
78181569	78181592	5	-	27260156	BXPC3	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.24029127838673459	[107]	[61,145,78,94]	-5	hSpCas9	negative selection	5528483
78181605	78181628	5	-	27260156	BXPC3	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.1976291167449009	[1040]	[746,789,1213,1092]	-4	hSpCas9	negative selection	5592765
78225589	78225612	5	-	27260156	BXPC3	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.32930691145829344	[454]	[359,417,338,395]	-6	hSpCas9	negative selection	5592766
78225579	78225602	5	+	27260156	BXPC3	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.41878043348465166	[1010]	[1306,1364,1505,1489]	8	hSpCas9	negative selection	5592767
78216082	78216105	5	-	27260156	A673	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.13878931085314195	[919]	[1272,785,859,1137]	-3	hSpCas9	negative selection	5649732
78216084	78216107	5	+	27260156	A673	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.08333377071842896	[135]	[168,167,94,187]	-2	hSpCas9	negative selection	5649733
78181569	78181592	5	-	27260156	A673	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.37183939814082523	[107]	[111,103,71,114]	-7	hSpCas9	negative selection	5649734
78181605	78181628	5	-	27260156	A673	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5073292633561405	[1040]	[919,796,898,907]	-8	hSpCas9	negative selection	5714016
78225589	78225612	5	-	27260156	A673	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.20561945787177122	[454]	[611,424,327,551]	-5	hSpCas9	negative selection	5714017
78225579	78225602	5	+	27260156	A673	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.42816355042750387	[1010]	[1759,1447,1780,1554]	8	hSpCas9	negative selection	5714018
78216082	78216105	5	-	27260156	A375	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.2067131366116879	[919]	[850,1161,906,842]	-3	hSpCas9	negative selection	5770983
78216084	78216107	5	+	27260156	A375	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-1.3541229212402606	[135]	[45,88,73,44]	-9	hSpCas9	negative selection	5770984
78181569	78181592	5	-	27260156	A375	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.33308278962981896	[107]	[115,145,56,88]	-5	hSpCas9	negative selection	5770985
78181605	78181628	5	-	27260156	A375	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5227750722517652	[1040]	[768,1035,971,653]	-6	hSpCas9	negative selection	5835267
78225589	78225612	5	-	27260156	A375	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.9957851070545135	[454]	[316,353,227,187]	-8	hSpCas9	negative selection	5835268
78225579	78225602	5	+	27260156	A375	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.66907236565354	[1010]	[1943,2278,1732,1632]	8	hSpCas9	negative selection	5835269
78216082	78216105	5	-	27260156	COLO741	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.11901420473279423	[919]	[1214,1086,962]	-3	hSpCas9	negative selection	5892234
78216084	78216107	5	+	27260156	COLO741	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.19072649571354572	[135]	[249,138,80]	-4	hSpCas9	negative selection	5892235
78181569	78181592	5	-	27260156	COLO741	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.16351915163150643	[107]	[101,175,91]	-4	hSpCas9	negative selection	5892236
78181605	78181628	5	-	27260156	COLO741	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5258869058960542	[1040]	[944,803,1014]	-8	hSpCas9	negative selection	5956518
78225589	78225612	5	-	27260156	COLO741	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.06245912568353988	[454]	[595,518,696]	1	hSpCas9	negative selection	5956519
78225579	78225602	5	+	27260156	COLO741	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.4800736154293026	[1010]	[2259,1834,1376]	8	hSpCas9	negative selection	5956520
78216082	78216105	5	-	27260156	CAL120	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.6340787485004638	[919]	[1030,551,674]	-7	hSpCas9	negative selection	6013485
78216084	78216107	5	+	27260156	CAL120	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.7684810414248473	[135]	[38,98,149]	-8	hSpCas9	negative selection	6013486
78181569	78181592	5	-	27260156	CAL120	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.1252008249087757	[107]	[211,117,119]	1	hSpCas9	negative selection	6013487
78181605	78181628	5	-	27260156	CAL120	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4776142374075468	[1040]	[1471,745,658]	-6	hSpCas9	negative selection	6077769
78225589	78225612	5	-	27260156	CAL120	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.13931664947767472	[454]	[649,483,429]	-2	hSpCas9	negative selection	6077770
78225579	78225602	5	+	27260156	CAL120	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.8335884936870461	[1010]	[2563,1765,2439]	9	hSpCas9	negative selection	6077771
78216082	78216105	5	-	27260156	CADOES1	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.02929564639312865	[919]	[944,781,1030,728]	0	hSpCas9	negative selection	6134736
78216084	78216107	5	+	27260156	CADOES1	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5083291400140999	[135]	[45,59,204,42]	-7	hSpCas9	negative selection	6134737
78181569	78181592	5	-	27260156	CADOES1	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.6750053656943553	[107]	[41,93,46,68]	-8	hSpCas9	negative selection	6134738
78181605	78181628	5	-	27260156	CADOES1	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.482849884029554	[1040]	[560,704,749,757]	-7	hSpCas9	negative selection	6199020
78225589	78225612	5	-	27260156	CADOES1	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.4607219500577506	[454]	[340,350,229,307]	-7	hSpCas9	negative selection	6199021
78225579	78225602	5	+	27260156	CADOES1	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.6656068470572138	[1010]	[1509,1416,1390,1653]	9	hSpCas9	negative selection	6199022
78216082	78216105	5	-	27260156	EWS502	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.6110573474679597	[919]	[580,552,740,689]	-7	hSpCas9	negative selection	6255987
78216084	78216107	5	+	27260156	EWS502	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5335046223495115	[135]	[149,47,105,88]	-7	hSpCas9	negative selection	6255988
78181569	78181592	5	-	27260156	EWS502	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.8354655661492996	[107]	[71,19,125,37]	-8	hSpCas9	negative selection	6255989
78181605	78181628	5	-	27260156	EWS502	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.7532495936391372	[1040]	[567,568,718,781]	-8	hSpCas9	negative selection	6320271
78225589	78225612	5	-	27260156	EWS502	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.6187111072026982	[454]	[285,281,309,385]	-7	hSpCas9	negative selection	6320272
78225579	78225602	5	+	27260156	EWS502	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5884115630092184	[1010]	[1677,1478,1615,1661]	8	hSpCas9	negative selection	6320273
78216082	78216105	5	-	27260156	EW8	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.10149775665953897	[919]	[721,685,530,868]	-2	hSpCas9	negative selection	6377238
78216084	78216107	5	+	27260156	EW8	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.04562603532970644	[135]	[52,185,102,79]	-1	hSpCas9	negative selection	6377239
78181569	78181592	5	-	27260156	EW8	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.15571837007238698	[107]	[80,83,113,105]	3	hSpCas9	negative selection	6377240
78181605	78181628	5	-	27260156	EW8	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4151200149333394	[1040]	[445,571,742,727]	-6	hSpCas9	negative selection	6441522
78225589	78225612	5	-	27260156	EW8	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.35754713649047115	[454]	[341,317,207,301]	-6	hSpCas9	negative selection	6441523
78225579	78225602	5	+	27260156	EW8	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.37945851521065843	[1010]	[952,1225,967,1117]	7	hSpCas9	negative selection	6441524
78216082	78216105	5	-	27260156	CORL105	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.0225629516990683	[919]	[1027,1044,1169,1142]	0	hSpCas9	negative selection	6498489
78216084	78216107	5	+	27260156	CORL105	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.13304265910339774	[135]	[199,124,192,184]	2	hSpCas9	negative selection	6498490
78181569	78181592	5	-	27260156	CORL105	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.49612136161246045	[107]	[123,135,69,25]	-7	hSpCas9	negative selection	6498491
78181605	78181628	5	-	27260156	CORL105	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4428869715293885	[1040]	[931,651,1127,915]	-7	hSpCas9	negative selection	6562773
78225589	78225612	5	-	27260156	CORL105	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.28195551196378865	[454]	[328,271,627,551]	-5	hSpCas9	negative selection	6562774
78225579	78225602	5	+	27260156	CORL105	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.3739828023732501	[1010]	[1617,1296,1898,1385]	7	hSpCas9	negative selection	6562775
78216082	78216105	5	-	27260156	HS294T	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.1278520832132355	[919]	[253,397,335,315]	-2	hSpCas9	negative selection	6619740
78216084	78216107	5	+	27260156	HS294T	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.020320156482741547	[135]	[31,32,96,46]	0	hSpCas9	negative selection	6619741
78181569	78181592	5	-	27260156	HS294T	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.322365177611069	[107]	[31,24,27,51]	-4	hSpCas9	negative selection	6619742
78181605	78181628	5	-	27260156	HS294T	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.06125039541305388	[1040]	[417,279,354,509]	-1	hSpCas9	negative selection	6684024
78225589	78225612	5	-	27260156	HS294T	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.11715010180220492	[454]	[124,249,170,226]	1	hSpCas9	negative selection	6684025
78225579	78225602	5	+	27260156	HS294T	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.2846664887477617	[1010]	[379,570,507,444]	4	hSpCas9	negative selection	6684026
78216082	78216105	5	-	27260156	HCC44	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.8743264508825549	[919]	[590,348,733,650]	-8	hSpCas9	negative selection	6740991
78216084	78216107	5	+	27260156	HCC44	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.11455492369495479	[135]	[142,136,127,156]	-2	hSpCas9	negative selection	6740992
78181569	78181592	5	-	27260156	HCC44	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.6813431411227602	[107]	[75,64,64,96]	-7	hSpCas9	negative selection	6740993
78181605	78181628	5	-	27260156	HCC44	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4462200165881456	[1040]	[1020,534,816,1120]	-6	hSpCas9	negative selection	6805275
78225589	78225612	5	-	27260156	HCC44	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.9801452090035973	[454]	[279,209,405,181]	-8	hSpCas9	negative selection	6805276
78225579	78225602	5	+	27260156	HCC44	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.35854657927714717	[1010]	[1950,1262,1242,1430]	6	hSpCas9	negative selection	6805277
78216082	78216105	5	-	27260156	G402	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.3655354413927103	[919]	[925,735,779,1031]	-4	hSpCas9	negative selection	6862242
78216084	78216107	5	+	27260156	G402	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.09660748355602533	[135]	[14,373,117,107]	-1	hSpCas9	negative selection	6862243
78181569	78181592	5	-	27260156	G402	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-1.3215685538544526	[107]	[67,25,35,79]	-9	hSpCas9	negative selection	6862244
78181605	78181628	5	-	27260156	G402	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.7021478855416929	[1040]	[774,1161,416,786]	-7	hSpCas9	negative selection	6926526
78225589	78225612	5	-	27260156	G402	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.6962277411952932	[454]	[217,478,526,144]	-7	hSpCas9	negative selection	6926527
78225579	78225602	5	+	27260156	G402	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.7746328400550986	[1010]	[2975,1878,1620,2070]	8	hSpCas9	negative selection	6926528
78216082	78216105	5	-	27260156	L33	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.17333589791669657	[919]	[828,369,508,721]	-4	hSpCas9	negative selection	6983493
78216084	78216107	5	+	27260156	L33	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.25912623170762994	[135]	[135,55,45,107]	-6	hSpCas9	negative selection	6983494
78181569	78181592	5	-	27260156	L33	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.19961875190869294	[107]	[92,87,34,132]	4	hSpCas9	negative selection	6983495
78181605	78181628	5	-	27260156	L33	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.27103257664460956	[1040]	[829,409,498,826]	-6	hSpCas9	negative selection	7047777
78225589	78225612	5	-	27260156	L33	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.22766700531987305	[454]	[409,152,231,400]	-5	hSpCas9	negative selection	7047778
78225579	78225602	5	+	27260156	L33	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.21813674150576068	[1010]	[1376,418,696,1189]	5	hSpCas9	negative selection	7047779
78216082	78216105	5	-	27260156	K562	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.4516957266143632	[919]	[657,780,354,604]	-5	hSpCas9	negative selection	7104744
78216084	78216107	5	+	27260156	K562	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-2.481852420420945	[135]	[19,20,21,22]	-9	hSpCas9	negative selection	7104745
78181569	78181592	5	-	27260156	K562	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.7793953110918048	[107]	[42,32,61,79]	-7	hSpCas9	negative selection	7104746
78181605	78181628	5	-	27260156	K562	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.7175614263339962	[1040]	[485,629,562,562]	-7	hSpCas9	negative selection	7169028
78225589	78225612	5	-	27260156	K562	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.4325034283656894	[454]	[297,298,455,158]	-5	hSpCas9	negative selection	7169029
78225579	78225602	5	+	27260156	K562	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5445175411633025	[1010]	[1022,1504,1221,1448]	7	hSpCas9	negative selection	7169030
78216082	78216105	5	-	27260156	HT29	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.30439904858380085	[919]	[1206,1090,711,673]	-5	hSpCas9	negative selection	7225995
78216084	78216107	5	+	27260156	HT29	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5349435052002633	[135]	[101,152,88,113]	-7	hSpCas9	negative selection	7225996
78181569	78181592	5	-	27260156	HT29	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.6687719799898435	[107]	[88,110,79,55]	-8	hSpCas9	negative selection	7225997
78181605	78181628	5	-	27260156	HT29	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4291503827708659	[1040]	[1062,950,979,787]	-7	hSpCas9	negative selection	7290279
78225589	78225612	5	-	27260156	HT29	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.33881687851070313	[454]	[403,621,399,344]	-6	hSpCas9	negative selection	7290280
78225579	78225602	5	+	27260156	HT29	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.3399913348446699	[1010]	[1652,1750,1488,1365]	6	hSpCas9	negative selection	7290281
78216082	78216105	5	-	27260156	MHHES1	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.04866332177275967	[919]	[1227,983,1001,834]	-1	hSpCas9	negative selection	7347246
78216084	78216107	5	+	27260156	MHHES1	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.328045781246151	[135]	[111,115,125,127]	-6	hSpCas9	negative selection	7347247
78181569	78181592	5	-	27260156	MHHES1	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.18134243322707366	[107]	[75,95,122,122]	-3	hSpCas9	negative selection	7347248
78181605	78181628	5	-	27260156	MHHES1	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.7471774923190754	[1040]	[762,843,837,421]	-8	hSpCas9	negative selection	7411530
78225589	78225612	5	-	27260156	MHHES1	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.3163132685725924	[454]	[238,746,368,316]	-5	hSpCas9	negative selection	7411531
78225579	78225602	5	+	27260156	MHHES1	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.4917172163442034	[1010]	[2016,1881,1202,1390]	8	hSpCas9	negative selection	7411532
78216082	78216105	5	-	27260156	MEWO	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.22947984677823674	[919]	[674,693,821]	-5	hSpCas9	negative selection	7468497
78216084	78216107	5	+	27260156	MEWO	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.25326354925772354	[135]	[182,106,44]	-5	hSpCas9	negative selection	7468498
78181569	78181592	5	-	27260156	MEWO	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.7498706488127884	[107]	[73,46,61]	-9	hSpCas9	negative selection	7468499
78181605	78181628	5	-	27260156	MEWO	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.3030349206245301	[1040]	[785,662,918]	-6	hSpCas9	negative selection	7532781
78225589	78225612	5	-	27260156	MEWO	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.08016152697769649	[454]	[361,412,424]	-2	hSpCas9	negative selection	7532782
78225579	78225602	5	+	27260156	MEWO	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.41929868998162334	[1010]	[1518,1173,1150]	8	hSpCas9	negative selection	7532783
78216082	78216105	5	-	27260156	LNCAPCLONEFGC	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.41123691496089787	[919]	[700,529,671,614]	-6	hSpCas9	negative selection	7589748
78216084	78216107	5	+	27260156	LNCAPCLONEFGC	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.3821340244728504	[135]	[37,27,292,53]	-5	hSpCas9	negative selection	7589749
78181569	78181592	5	-	27260156	LNCAPCLONEFGC	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.325313259768214	[107]	[83,77,49,95]	-5	hSpCas9	negative selection	7589750
78181605	78181628	5	-	27260156	LNCAPCLONEFGC	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.7092445100417524	[1040]	[686,588,564,460]	-8	hSpCas9	negative selection	7654032
78225589	78225612	5	-	27260156	LNCAPCLONEFGC	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.9362880596968273	[454]	[177,142,343,220]	-8	hSpCas9	negative selection	7654033
78225579	78225602	5	+	27260156	LNCAPCLONEFGC	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.597474675500443	[1010]	[1163,1202,1619,1605]	8	hSpCas9	negative selection	7654034
78216082	78216105	5	-	27260156	PANC0327	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.36738861391432964	[919]	[611,507,549,877]	-5	hSpCas9	negative selection	7710999
78216084	78216107	5	+	27260156	PANC0327	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.17971064851549734	[135]	[214,132,29,175]	2	hSpCas9	negative selection	7711000
78181569	78181592	5	-	27260156	PANC0327	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.23666163462158263	[107]	[22,79,71,145]	-4	hSpCas9	negative selection	7711001
78181605	78181628	5	-	27260156	PANC0327	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.07594253378313787	[1040]	[720,737,900,1153]	-1	hSpCas9	negative selection	7775283
78225589	78225612	5	-	27260156	PANC0327	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.29196065949890054	[454]	[270,301,266,478]	-4	hSpCas9	negative selection	7775284
78225579	78225602	5	+	27260156	PANC0327	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.35742297088211106	[1010]	[1125,891,1127,1486]	5	hSpCas9	negative selection	7775285
78216082	78216105	5	-	27260156	NCIH2009	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.31558443151463833	[919]	[1123,1130,857]	-4	hSpCas9	negative selection	7832250
78216084	78216107	5	+	27260156	NCIH2009	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.12065062403748827	[135]	[311,109,219]	1	hSpCas9	negative selection	7832251
78181569	78181592	5	-	27260156	NCIH2009	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-1.9247563823531575	[107]	[42,28,47]	-9	hSpCas9	negative selection	7832252
78181605	78181628	5	-	27260156	NCIH2009	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.46290449596681327	[1040]	[957,1147,1036]	-6	hSpCas9	negative selection	7896534
78225589	78225612	5	-	27260156	NCIH2009	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.566438016591269	[454]	[408,379,494]	-6	hSpCas9	negative selection	7896535
78225579	78225602	5	+	27260156	NCIH2009	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.24848428803869105	[1010]	[2007,1591,1497]	3	hSpCas9	negative selection	7896536
78216082	78216105	5	-	27260156	NCIH1373	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.6644837602249614	[919]	[661,582,668,182]	-6	hSpCas9	negative selection	7953501
78216084	78216107	5	+	27260156	NCIH1373	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-1.8522023575043713	[135]	[23,83,18,8]	-9	hSpCas9	negative selection	7953502
78181569	78181592	5	-	27260156	NCIH1373	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.04820157092866273	[107]	[19,306,16,31]	0	hSpCas9	negative selection	7953503
78181605	78181628	5	-	27260156	NCIH1373	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.6645997404310366	[1040]	[507,831,747,212]	-6	hSpCas9	negative selection	8017785
78225589	78225612	5	-	27260156	NCIH1373	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.977891862573845	[454]	[188,141,389,82]	-7	hSpCas9	negative selection	8017786
78225579	78225602	5	+	27260156	NCIH1373	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.3637217640436974	[1010]	[1453,1393,1404,416]	3	hSpCas9	negative selection	8017787
78216082	78216105	5	-	27260156	PATU8902	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.7997734495211238	[919]	[936,423,847,690]	-6	hSpCas9	negative selection	8074752
78216084	78216107	5	+	27260156	PATU8902	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-1.632686218776701	[135]	[80,64,56,38]	-8	hSpCas9	negative selection	8074753
78181569	78181592	5	-	27260156	PATU8902	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.7094177187111081	[107]	[110,26,188,3]	-6	hSpCas9	negative selection	8074754
78181605	78181628	5	-	27260156	PATU8902	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.24529158263012774	[1040]	[1091,966,793,2266]	-2	hSpCas9	negative selection	8139036
78225589	78225612	5	-	27260156	PATU8902	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-2.9751872901734897	[454]	[62,96,96,57]	-9	hSpCas9	negative selection	8139037
78225579	78225602	5	+	27260156	PATU8902	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.6453897332975875	[1010]	[2952,1440,1788,2771]	6	hSpCas9	negative selection	8139038
78216082	78216105	5	-	27260156	PANC1	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.2443509554508405	[919]	[989,926,1150,698]	4	hSpCas9	negative selection	8196003
78216084	78216107	5	+	27260156	PANC1	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5082034729240739	[135]	[93,108,118,20]	-6	hSpCas9	negative selection	8196004
78181569	78181592	5	-	27260156	PANC1	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.9347282817239329	[107]	[35,126,28,21]	-8	hSpCas9	negative selection	8196005
78181605	78181628	5	-	27260156	PANC1	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.45427519738140143	[1040]	[603,757,826,465]	-6	hSpCas9	negative selection	8260287
78225589	78225612	5	-	27260156	PANC1	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	0.004868860457214283	[454]	[548,379,440,215]	0	hSpCas9	negative selection	8260288
78225579	78225602	5	+	27260156	PANC1	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5295088562714683	[1010]	[1444,1449,1104,1059]	8	hSpCas9	negative selection	8260289
78216082	78216105	5	-	27260156	PANC0813	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.8020105024863662	[919]	[693,551,616,621]	-8	hSpCas9	negative selection	8317254
78216084	78216107	5	+	27260156	PANC0813	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.9084923757671131	[135]	[65,48,124,97]	-8	hSpCas9	negative selection	8317255
78181569	78181592	5	-	27260156	PANC0813	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.9800918585139944	[107]	[67,24,122,42]	-8	hSpCas9	negative selection	8317256
78181605	78181628	5	-	27260156	PANC0813	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-1.0054046875703322	[1040]	[554,764,520,589]	-8	hSpCas9	negative selection	8381538
78225589	78225612	5	-	27260156	PANC0813	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-1.0962013596198177	[454]	[206,268,223,292]	-8	hSpCas9	negative selection	8381539
78225579	78225602	5	+	27260156	PANC0813	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.27535068855922185	[1010]	[1580,1503,1681,1017]	4	hSpCas9	negative selection	8381540
78216082	78216105	5	-	27260156	RDES	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.35641088383662933	[919]	[741,731,754,1119]	-6	hSpCas9	negative selection	8438505
78216084	78216107	5	+	27260156	RDES	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.7331699061068166	[135]	[103,62,88,121]	-8	hSpCas9	negative selection	8438506
78181569	78181592	5	-	27260156	RDES	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.7117147003991238	[107]	[59,53,120,72]	-8	hSpCas9	negative selection	8438507
78181605	78181628	5	-	27260156	RDES	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5204441815472934	[1040]	[694,732,844,1124]	-7	hSpCas9	negative selection	8502789
78225589	78225612	5	-	27260156	RDES	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.3705356343043865	[454]	[291,433,393,526]	-6	hSpCas9	negative selection	8502790
78225579	78225602	5	+	27260156	RDES	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5724180041902227	[1010]	[1588,1668,1867,1781]	8	hSpCas9	negative selection	8502791
78216082	78216105	5	-	27260156	PC3	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	0.02389081955271899	[919]	[653,921,1624,814]	0	hSpCas9	negative selection	8559756
78216084	78216107	5	+	27260156	PC3	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.48572265981317364	[135]	[78,100,126,86]	-8	hSpCas9	negative selection	8559757
78181569	78181592	5	-	27260156	PC3	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	0.2543022234079906	[107]	[41,64,172,292]	5	hSpCas9	negative selection	8559758
78181605	78181628	5	-	27260156	PC3	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.22602370074386702	[1040]	[545,855,1618,878]	-5	hSpCas9	negative selection	8624040
78225589	78225612	5	-	27260156	PC3	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.16835333153784898	[454]	[187,510,503,511]	-4	hSpCas9	negative selection	8624041
78225579	78225602	5	+	27260156	PC3	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.29725484867224283	[1010]	[735,1110,2415,1263]	6	hSpCas9	negative selection	8624042
78216082	78216105	5	-	27260156	PATU8988T	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.2976266307283596	[919]	[725,725,593,859]	-5	hSpCas9	negative selection	8681007
78216084	78216107	5	+	27260156	PATU8988T	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.004941385774270168	[135]	[72,83,220,140]	0	hSpCas9	negative selection	8681008
78181569	78181592	5	-	27260156	PATU8988T	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-1.2747803509767919	[107]	[80,14,50,20]	-9	hSpCas9	negative selection	8681009
78181605	78181628	5	-	27260156	PATU8988T	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.25728929618717644	[1040]	[829,592,1111,800]	-4	hSpCas9	negative selection	8745291
78225589	78225612	5	-	27260156	PATU8988T	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.049518956554975006	[454]	[656,367,279,387]	-1	hSpCas9	negative selection	8745292
78225579	78225602	5	+	27260156	PATU8988T	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.47933810433181745	[1010]	[1550,1372,1177,1347]	7	hSpCas9	negative selection	8745293
78216082	78216105	5	-	27260156	T47D	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.27088068964344403	[919]	[973,874,849,854]	-5	hSpCas9	negative selection	8802258
78216084	78216107	5	+	27260156	T47D	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.3509738699037357	[135]	[126,138,102,126]	-6	hSpCas9	negative selection	8802259
78181569	78181592	5	-	27260156	T47D	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.15591424598726267	[107]	[119,91,113,127]	-3	hSpCas9	negative selection	8802260
78181605	78181628	5	-	27260156	T47D	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.183839088659292	[1040]	[917,1053,1030,1274]	-4	hSpCas9	negative selection	8866542
78225589	78225612	5	-	27260156	T47D	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.1332724136564879	[454]	[444,396,497,603]	-3	hSpCas9	negative selection	8866543
78225579	78225602	5	+	27260156	T47D	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5662426438732104	[1010]	[1806,1516,1828,1843]	9	hSpCas9	negative selection	8866544
78216082	78216105	5	-	27260156	SU8686	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.15917911406311336	[919]	[722,754,820,1012]	-3	hSpCas9	negative selection	8923509
78216084	78216107	5	+	27260156	SU8686	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	0.29213492883729786	[135]	[149,168,155,188]	5	hSpCas9	negative selection	8923510
78181569	78181592	5	-	27260156	SU8686	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.07224084780384876	[107]	[131,79,83,110]	-1	hSpCas9	negative selection	8923511
78181605	78181628	5	-	27260156	SU8686	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.42649800244266667	[1040]	[646,656,908,907]	-6	hSpCas9	negative selection	8987793
78225589	78225612	5	-	27260156	SU8686	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.2483199653992048	[454]	[307,350,444,434]	-4	hSpCas9	negative selection	8987794
78225579	78225602	5	+	27260156	SU8686	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5543676037196064	[1010]	[1384,1333,1562,1654]	8	hSpCas9	negative selection	8987795
78216082	78216105	5	-	27260156	SKES1	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.08301778351854261	[919]	[1141,867,921,594]	-2	hSpCas9	negative selection	9044760
78216084	78216107	5	+	27260156	SKES1	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.2744787965490103	[135]	[149,152,68,88]	-6	hSpCas9	negative selection	9044761
78181569	78181592	5	-	27260156	SKES1	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.5123653618491817	[107]	[40,52,69,123]	-8	hSpCas9	negative selection	9044762
78181605	78181628	5	-	27260156	SKES1	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5566762472164141	[1040]	[598,699,901,608]	-8	hSpCas9	negative selection	9109044
78225589	78225612	5	-	27260156	SKES1	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.3646063560496012	[454]	[365,432,308,314]	-7	hSpCas9	negative selection	9109045
78225579	78225602	5	+	27260156	SKES1	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.47325428219092336	[1010]	[1627,1433,1222,1344]	8	hSpCas9	negative selection	9109046
78216082	78216105	5	-	27260156	TOV112D	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.2023951790984453	[919]	[861,1129,563,733]	-4	hSpCas9	negative selection	9166011
78216084	78216107	5	+	27260156	TOV112D	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.3384432879386139	[135]	[94,203,69,84]	-6	hSpCas9	negative selection	9166012
78181569	78181592	5	-	27260156	TOV112D	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.3462982386590099	[107]	[44,188,28,98]	-6	hSpCas9	negative selection	9166013
78181605	78181628	5	-	27260156	TOV112D	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.5247253408408761	[1040]	[960,675,559,708]	-8	hSpCas9	negative selection	9230295
78225589	78225612	5	-	27260156	TOV112D	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.493366283609643	[454]	[259,563,232,291]	-7	hSpCas9	negative selection	9230296
78225579	78225602	5	+	27260156	TOV112D	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.3052043166198324	[1010]	[1343,1296,1182,1198]	6	hSpCas9	negative selection	9230297
78216082	78216105	5	-	27260156	TC71	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.2442922285112883	[919]	[791,899,746,898]	-6	hSpCas9	negative selection	9287262
78216084	78216107	5	+	27260156	TC71	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.32158335215429923	[135]	[85,145,100,135]	-7	hSpCas9	negative selection	9287263
78181569	78181592	5	-	27260156	TC71	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.06802799227370748	[107]	[141,100,75,123]	-2	hSpCas9	negative selection	9287264
78181605	78181628	5	-	27260156	TC71	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.2348853298492748	[1040]	[874,994,1000,919]	-6	hSpCas9	negative selection	9351546
78225589	78225612	5	-	27260156	TC71	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.03935851901441915	[454]	[464,453,559,412]	-1	hSpCas9	negative selection	9351547
78225579	78225602	5	+	27260156	TC71	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.40015402162030567	[1010]	[1218,1513,1328,1681]	8	hSpCas9	negative selection	9351548
78216082	78216105	5	-	27260156	TC32	viability	ACATGCTAACTCGATATGCTCGG	AP3B1	ENSG00000132842	-0.36082280197929983	[919]	[585,400,1095,765]	-6	hSpCas9	negative selection	9408513
78216084	78216107	5	+	27260156	TC32	viability	GAGCATATCGAGTTAGCATGTGG	AP3B1	ENSG00000132842	-0.5789755203982339	[135]	[96,68,70,102]	-8	hSpCas9	negative selection	9408514
78181569	78181592	5	-	27260156	TC32	viability	AAAGAAGAAGCCGTATACTATGG	AP3B1	ENSG00000132842	-0.4971009560363213	[107]	[69,39,123,70]	-7	hSpCas9	negative selection	9408515
78181605	78181628	5	-	27260156	TC32	viability	CGAATCTGATGATGATCAGAAGG	AP3B1	ENSG00000132842	-0.4422814241180866	[1040]	[591,677,856,765]	-7	hSpCas9	negative selection	9472797
78225589	78225612	5	-	27260156	TC32	viability	TAGCCTTGATCCAGAGCAGAAGG	AP3B1	ENSG00000132842	-0.4811767518771147	[454]	[305,180,452,342]	-7	hSpCas9	negative selection	9472798
78225579	78225602	5	+	27260156	TC32	viability	ATTAACATTTCCTTCTGCTCTGG	AP3B1	ENSG00000132842	0.5003811611051001	[1010]	[1215,863,2118,1438]	8	hSpCas9	negative selection	9472799
78089460	78089483	5	+	27869803	HPAFII	viability after 27 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.6532981971653251	[198]	[109,209,NaN]	5	hSpCas9	negative selection	9592637
78128125	78128148	5	+	27869803	HPAFII	viability after 27 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.006273085998310668	[119]	[100,31,NaN]	0	hSpCas9	negative selection	9592638
78228188	78228211	5	-	27869803	HPAFII	viability after 27 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.2944868611635831	[150]	[275,126,NaN]	9	hSpCas9	negative selection	9592639
78294460	78294483	5	+	27869803	HPAFII	viability after 27 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.46639692897681373	[102]	[106,47,NaN]	4	hSpCas9	negative selection	9592640
78294535	78294558	5	-	27869803	HPAFII	viability after 27 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.5318511642615936	[284]	[143,69,NaN]	-4	hSpCas9	negative selection	9592641
78089460	78089483	5	+	27869803	HPAFII	viability after 15 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.5064479530036088	[198]	[280,317,NaN]	6	hSpCas9	negative selection	9675086
78128125	78128148	5	+	27869803	HPAFII	viability after 15 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.40053126218513735	[119]	[130,76,NaN]	-4	hSpCas9	negative selection	9675087
78228188	78228211	5	-	27869803	HPAFII	viability after 15 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.0155537167441784	[150]	[361,306,NaN]	9	hSpCas9	negative selection	9675088
78294460	78294483	5	+	27869803	HPAFII	viability after 15 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.6860173718851809	[102]	[285,110,NaN]	7	hSpCas9	negative selection	9675089
78294535	78294558	5	-	27869803	HPAFII	viability after 15 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.31743884344705187	[284]	[267,231,NaN]	-4	hSpCas9	negative selection	9675090
78089460	78089483	5	+	27869803	ASPC1	viability after 36 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	1.3174381482630961	[479]	[289,779,214]	9	hSpCas9	negative selection	9757535
78128125	78128148	5	+	27869803	ASPC1	viability after 36 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.24430111381327335	[299]	[178,54,138]	2	hSpCas9	negative selection	9757536
78228188	78228211	5	-	27869803	ASPC1	viability after 36 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	-0.35339595256519585	[404]	[86,106,128]	-4	hSpCas9	negative selection	9757537
78294460	78294483	5	+	27869803	ASPC1	viability after 36 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.3209290646592309	[201]	[142,40,85]	3	hSpCas9	negative selection	9757538
78294535	78294558	5	-	27869803	ASPC1	viability after 36 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.8540558504749145	[696]	[871,246,284]	7	hSpCas9	negative selection	9757539
78089460	78089483	5	+	27869803	PATU8988S	viability after 35 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.1819526241474515	[489]	[168,278,NaN]	2	hSpCas9	negative selection	9839984
78128125	78128148	5	+	27869803	PATU8988S	viability after 35 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	0.4279695234201601	[297]	[146,175,NaN]	5	hSpCas9	negative selection	9839985
78228188	78228211	5	-	27869803	PATU8988S	viability after 35 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.5483770911216065	[313]	[160,208,NaN]	6	hSpCas9	negative selection	9839986
78294460	78294483	5	+	27869803	PATU8988S	viability after 35 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.07816981169636228	[154]	[22,108,NaN]	0	hSpCas9	negative selection	9839987
78294535	78294558	5	-	27869803	PATU8988S	viability after 35 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.1986931220600946	[590]	[163,250,NaN]	-2	hSpCas9	negative selection	9839988
78089460	78089483	5	+	27869803	PATU8988S	viability after 31 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.3596644021655338	[489]	[167,355,NaN]	4	hSpCas9	negative selection	9922433
78128125	78128148	5	+	27869803	PATU8988S	viability after 31 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.1621291441609276	[297]	[81,136,NaN]	-2	hSpCas9	negative selection	9922434
78228188	78228211	5	-	27869803	PATU8988S	viability after 31 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.6453206307105283	[313]	[157,243,NaN]	7	hSpCas9	negative selection	9922435
78294460	78294483	5	+	27869803	PATU8988S	viability after 31 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.7666120468801336	[154]	[43,182,NaN]	8	hSpCas9	negative selection	9922436
78294535	78294558	5	-	27869803	PATU8988S	viability after 31 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.2203773642722774	[590]	[174,236,NaN]	-3	hSpCas9	negative selection	9922437
78089460	78089483	5	+	27869803	HPAFII	viability after 35 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	1.0643182702926168	[198]	[141,287,NaN]	7	hSpCas9	negative selection	10004882
78128125	78128148	5	+	27869803	HPAFII	viability after 35 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-1.040323810344161	[119]	[45,10,NaN]	-5	hSpCas9	negative selection	10004883
78228188	78228211	5	-	27869803	HPAFII	viability after 35 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	1.2423950852627432	[150]	[249,102,NaN]	8	hSpCas9	negative selection	10004884
78294460	78294483	5	+	27869803	HPAFII	viability after 35 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.9972882901604656	[102]	[168,30,NaN]	6	hSpCas9	negative selection	10004885
78294535	78294558	5	-	27869803	HPAFII	viability after 35 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	0.05582300013781907	[284]	[93,212,NaN]	0	hSpCas9	negative selection	10004886
78089460	78089483	5	+	27869803	HPAFII	viability after 31 days	GCTGGTGTGGGAAGTGCAACTGG	AP3B1	ENSG00000132842	0.7814406964381899	[198]	[112,277,NaN]	6	hSpCas9	negative selection	10087331
78128125	78128148	5	+	27869803	HPAFII	viability after 31 days	TATGAGATAAGGTGCCAAGCTGG	AP3B1	ENSG00000132842	-0.06998140609865433	[119]	[89,35,NaN]	0	hSpCas9	negative selection	10087332
78228188	78228211	5	-	27869803	HPAFII	viability after 31 days	TCGATATGCTGAAGAACAGCAGG	AP3B1	ENSG00000132842	0.9079142252767765	[150]	[214,97,NaN]	6	hSpCas9	negative selection	10087333
78294460	78294483	5	+	27869803	HPAFII	viability after 31 days	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.3912684889586875	[102]	[93,55,NaN]	3	hSpCas9	negative selection	10087334
78294535	78294558	5	-	27869803	HPAFII	viability after 31 days	ACAATGAGCAGTCCGGAGGAGGG	AP3B1	ENSG00000132842	-0.008434337719294943	[284]	[136,182,NaN]	0	hSpCas9	negative selection	10087335
78294531	78294554	5	-	28162770	P31FUJ	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.06148313540385486	[273]	[335]	0	hSpCas9	negative selection	10111675
78162834	78162857	5	+	28162770	P31FUJ	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.22770112038156587	[366]	[504]	2	hSpCas9	negative selection	10111676
78181506	78181529	5	-	28162770	P31FUJ	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.23268431755182284	[280]	[387]	2	hSpCas9	negative selection	10111677
78128074	78128097	5	-	28162770	P31FUJ	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.5017366523572877	[118]	[197]	5	hSpCas9	negative selection	10111678
78113758	78113781	5	-	28162770	P31FUJ	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	1.0697605656060525	[104]	[258]	9	hSpCas9	negative selection	10111679
78294460	78294483	5	+	28162770	P31FUJ	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.3516796002662987	[176]	[162]	-3	hSpCas9	negative selection	10111680
78129123	78129146	5	+	28162770	P31FUJ	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.16171910635289594	[296]	[311]	-1	hSpCas9	negative selection	10111681
78113876	78113899	5	-	28162770	P31FUJ	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	0.8796725248440338	[36]	[79]	8	hSpCas9	negative selection	10111682
78015463	78015486	5	+	28162770	P31FUJ	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.25558703661172455	[277]	[389]	2	hSpCas9	negative selection	10111683
78267529	78267552	5	-	28162770	P31FUJ	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.3886861723318916	[90]	[139]	4	hSpCas9	negative selection	10111684
78294531	78294554	5	-	28162770	TF1	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10281041
78162834	78162857	5	+	28162770	TF1	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10281042
78181506	78181529	5	-	28162770	TF1	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10281043
78128074	78128097	5	-	28162770	TF1	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10281044
78113758	78113781	5	-	28162770	TF1	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10281045
78294460	78294483	5	+	28162770	TF1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10281046
78129123	78129146	5	+	28162770	TF1	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10281047
78113876	78113899	5	-	28162770	TF1	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10281048
78015463	78015486	5	+	28162770	TF1	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10281049
78267529	78267552	5	-	28162770	TF1	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10281050
78294531	78294554	5	-	28162770	SKM1	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.17799830197799454	[76]	[153]	1	hSpCas9	negative selection	10450407
78162834	78162857	5	+	28162770	SKM1	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.07891852826999202	[112]	[210]	0	hSpCas9	negative selection	10450408
78181506	78181529	5	-	28162770	SKM1	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.03650620992814069	[75]	[130]	0	hSpCas9	negative selection	10450409
78128074	78128097	5	-	28162770	SKM1	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10450410
78113758	78113781	5	-	28162770	SKM1	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	-0.3931583992181311	[25]	[34]	-3	hSpCas9	negative selection	10450411
78294460	78294483	5	+	28162770	SKM1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.2370391973008493	[55]	[83]	-2	hSpCas9	negative selection	10450412
78129123	78129146	5	+	28162770	SKM1	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.02302364200165357	[53]	[96]	0	hSpCas9	negative selection	10450413
78113876	78113899	5	-	28162770	SKM1	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	2.145817896228845	[16]	[132]	9	hSpCas9	negative selection	10450414
78015463	78015486	5	+	28162770	SKM1	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.14431517572170577	[64]	[126]	1	hSpCas9	negative selection	10450415
78267529	78267552	5	-	28162770	SKM1	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.75787136060229	[21]	[22]	-5	hSpCas9	negative selection	10450416
78294531	78294554	5	-	28162770	SKM1	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.17799830197799454	[76]	[153]	1	hSpCas9	negative selection	10619773
78162834	78162857	5	+	28162770	SKM1	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.07891852826999202	[112]	[210]	0	hSpCas9	negative selection	10619774
78181506	78181529	5	-	28162770	SKM1	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.03650620992814069	[75]	[130]	0	hSpCas9	negative selection	10619775
78128074	78128097	5	-	28162770	SKM1	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10619776
78113758	78113781	5	-	28162770	SKM1	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	-0.3931583992181311	[25]	[34]	-3	hSpCas9	negative selection	10619777
78294460	78294483	5	+	28162770	SKM1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.2370391973008493	[55]	[83]	-2	hSpCas9	negative selection	10619778
78129123	78129146	5	+	28162770	SKM1	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.02302364200165357	[53]	[96]	0	hSpCas9	negative selection	10619779
78113876	78113899	5	-	28162770	SKM1	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	2.145817896228845	[16]	[132]	9	hSpCas9	negative selection	10619780
78015463	78015486	5	+	28162770	SKM1	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.14431517572170577	[64]	[126]	1	hSpCas9	negative selection	10619781
78267529	78267552	5	-	28162770	SKM1	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.75787136060229	[21]	[22]	-5	hSpCas9	negative selection	10619782
78294531	78294554	5	-	28162770	PL21	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.045070217996486694	[313]	[140]	0	hSpCas9	negative selection	10789139
78162834	78162857	5	+	28162770	PL21	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.39323512604803595	[343]	[113]	-3	hSpCas9	negative selection	10789140
78181506	78181529	5	-	28162770	PL21	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.17022883545579548	[317]	[122]	-1	hSpCas9	negative selection	10789141
78128074	78128097	5	-	28162770	PL21	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.605591064938966	[150]	[99]	5	hSpCas9	negative selection	10789142
78113758	78113781	5	-	28162770	PL21	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.5537765691040206	[107]	[68]	5	hSpCas9	negative selection	10789143
78294460	78294483	5	+	28162770	PL21	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.5345586535598794	[183]	[115]	4	hSpCas9	negative selection	10789144
78129123	78129146	5	+	28162770	PL21	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.05361697775646301	[216]	[90]	0	hSpCas9	negative selection	10789145
78113876	78113899	5	-	28162770	PL21	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	0.7957493594099849	[44]	[33]	6	hSpCas9	negative selection	10789146
78015463	78015486	5	+	28162770	PL21	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.7249811227729055	[195]	[140]	6	hSpCas9	negative selection	10789147
78267529	78267552	5	-	28162770	PL21	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.23490503264999663	[81]	[41]	2	hSpCas9	negative selection	10789148
78294531	78294554	5	-	28162770	P31FUJ	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.06148313540385486	[273]	[335]	0	hSpCas9	negative selection	10958505
78162834	78162857	5	+	28162770	P31FUJ	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.22770112038156587	[366]	[504]	2	hSpCas9	negative selection	10958506
78181506	78181529	5	-	28162770	P31FUJ	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.23268431755182284	[280]	[387]	2	hSpCas9	negative selection	10958507
78128074	78128097	5	-	28162770	P31FUJ	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.5017366523572877	[118]	[197]	5	hSpCas9	negative selection	10958508
78113758	78113781	5	-	28162770	P31FUJ	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	1.0697605656060525	[104]	[258]	9	hSpCas9	negative selection	10958509
78294460	78294483	5	+	28162770	P31FUJ	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.3516796002662987	[176]	[162]	-3	hSpCas9	negative selection	10958510
78129123	78129146	5	+	28162770	P31FUJ	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.16171910635289594	[296]	[311]	-1	hSpCas9	negative selection	10958511
78113876	78113899	5	-	28162770	P31FUJ	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	0.8796725248440338	[36]	[79]	8	hSpCas9	negative selection	10958512
78015463	78015486	5	+	28162770	P31FUJ	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.25558703661172455	[277]	[389]	2	hSpCas9	negative selection	10958513
78267529	78267552	5	-	28162770	P31FUJ	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.3886861723318916	[90]	[139]	4	hSpCas9	negative selection	10958514
78294531	78294554	5	-	28162770	OCIAML5	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.9667091368051197	[143]	[132]	-6	hSpCas9	negative selection	11127871
78162834	78162857	5	+	28162770	OCIAML5	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.29647867227635427	[214]	[315]	-2	hSpCas9	negative selection	11127872
78181506	78181529	5	-	28162770	OCIAML5	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-1.3342182660013777	[175]	[125]	-6	hSpCas9	negative selection	11127873
78128074	78128097	5	-	28162770	OCIAML5	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.3304114809214001	[88]	[201]	3	hSpCas9	negative selection	11127874
78113758	78113781	5	-	28162770	OCIAML5	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	-0.14878410295407962	[77]	[126]	-1	hSpCas9	negative selection	11127875
78294460	78294483	5	+	28162770	OCIAML5	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.1152672402156808	[66]	[130]	0	hSpCas9	negative selection	11127876
78129123	78129146	5	+	28162770	OCIAML5	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.09476797460078434	[154]	[261]	0	hSpCas9	negative selection	11127877
78113876	78113899	5	-	28162770	OCIAML5	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.9432144589221922	[48]	[45]	-5	hSpCas9	negative selection	11127878
78015463	78015486	5	+	28162770	OCIAML5	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.5264450523897329	[119]	[311]	4	hSpCas9	negative selection	11127879
78267529	78267552	5	-	28162770	OCIAML5	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-1.3045787755615035	[51]	[37]	-6	hSpCas9	negative selection	11127880
78294531	78294554	5	-	28162770	EOL1	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.8842085056636817	[514]	[146]	-6	hSpCas9	negative selection	11297237
78162834	78162857	5	+	28162770	EOL1	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.004274964041268592	[527]	[278]	0	hSpCas9	negative selection	11297238
78181506	78181529	5	-	28162770	EOL1	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-1.02255727999734	[481]	[124]	-6	hSpCas9	negative selection	11297239
78128074	78128097	5	-	28162770	EOL1	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.23785538388555202	[234]	[145]	2	hSpCas9	negative selection	11297240
78113758	78113781	5	-	28162770	EOL1	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.7299003407169908	[205]	[179]	6	hSpCas9	negative selection	11297241
78294460	78294483	5	+	28162770	EOL1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.47940622857929294	[388]	[146]	-4	hSpCas9	negative selection	11297242
78129123	78129146	5	+	28162770	EOL1	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.6652641288120175	[297]	[98]	-5	hSpCas9	negative selection	11297243
78113876	78113899	5	-	28162770	EOL1	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.16034112601597839	[69]	[32]	-1	hSpCas9	negative selection	11297244
78015463	78015486	5	+	28162770	EOL1	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.7819767090315349	[296]	[90]	-5	hSpCas9	negative selection	11297245
78267529	78267552	5	-	28162770	EOL1	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.1492540587452289	[88]	[51]	1	hSpCas9	negative selection	11297246
78294531	78294554	5	-	28162770	MOLM13	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.22984104933852706	[398]	[245]	-1	hSpCas9	negative selection	11466603
78162834	78162857	5	+	28162770	MOLM13	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.4252750374841989	[480]	[466]	3	hSpCas9	negative selection	11466604
78181506	78181529	5	-	28162770	MOLM13	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	1.3770002403782098	[302]	[568]	9	hSpCas9	negative selection	11466605
78128074	78128097	5	-	28162770	MOLM13	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.40234274348509136	[169]	[92]	-2	hSpCas9	negative selection	11466606
78113758	78113781	5	-	28162770	MOLM13	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	-0.4801828264115603	[190]	[98]	-3	hSpCas9	negative selection	11466607
78294460	78294483	5	+	28162770	MOLM13	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.5670647866354143	[266]	[285]	4	hSpCas9	negative selection	11466608
78129123	78129146	5	+	28162770	MOLM13	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-0.05226482354847917	[369]	[257]	0	hSpCas9	negative selection	11466609
78113876	78113899	5	-	28162770	MOLM13	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-1.175966808230146	[74]	[23]	-6	hSpCas9	negative selection	11466610
78015463	78015486	5	+	28162770	MOLM13	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.047498647771528346	[359]	[268]	0	hSpCas9	negative selection	11466611
78267529	78267552	5	-	28162770	MOLM13	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.3606301505110674	[102]	[57]	-2	hSpCas9	negative selection	11466612
78294531	78294554	5	-	28162770	HEL	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.07363028248003789	[361]	[243]	0	hSpCas9	negative selection	11635969
78162834	78162857	5	+	28162770	HEL	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.20592439032626153	[355]	[262]	1	hSpCas9	negative selection	11635970
78181506	78181529	5	-	28162770	HEL	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.11323873069165263	[330]	[195]	-1	hSpCas9	negative selection	11635971
78128074	78128097	5	-	28162770	HEL	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.07185894913739471	[191]	[116]	0	hSpCas9	negative selection	11635972
78113758	78113781	5	-	28162770	HEL	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.4774011000536964	[156]	[139]	4	hSpCas9	negative selection	11635973
78294460	78294483	5	+	28162770	HEL	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.10916171754611209	[261]	[180]	0	hSpCas9	negative selection	11635974
78129123	78129146	5	+	28162770	HEL	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	-1.1072829149912957	[221]	[65]	-6	hSpCas9	negative selection	11635975
78113876	78113899	5	-	28162770	HEL	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	1.1158084526506156	[66]	[92]	8	hSpCas9	negative selection	11635976
78015463	78015486	5	+	28162770	HEL	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.8328402092135376	[291]	[104]	-5	hSpCas9	negative selection	11635977
78267529	78267552	5	-	28162770	HEL	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.9677009869773525	[94]	[118]	8	hSpCas9	negative selection	11635978
78294531	78294554	5	-	28162770	MV411	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.5635286248272076	[299]	[170]	-4	hSpCas9	negative selection	11805335
78162834	78162857	5	+	28162770	MV411	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.4400826287251711	[300]	[343]	4	hSpCas9	negative selection	11805336
78181506	78181529	5	-	28162770	MV411	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.42461056670209246	[238]	[149]	-3	hSpCas9	negative selection	11805337
78128074	78128097	5	-	28162770	MV411	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	1.2367111441897167	[134]	[267]	9	hSpCas9	negative selection	11805338
78113758	78113781	5	-	28162770	MV411	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	1.1231094157805737	[108]	[199]	8	hSpCas9	negative selection	11805339
78294460	78294483	5	+	28162770	MV411	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.6967449521463653	[155]	[212]	6	hSpCas9	negative selection	11805340
78129123	78129146	5	+	28162770	MV411	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.8179295686955983	[166]	[247]	7	hSpCas9	negative selection	11805341
78113876	78113899	5	-	28162770	MV411	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-1.521949521075808	[74]	[21]	-7	hSpCas9	negative selection	11805342
78015463	78015486	5	+	28162770	MV411	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.701750198795059	[153]	[210]	6	hSpCas9	negative selection	11805343
78267529	78267552	5	-	28162770	MV411	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	-0.29570477424375397	[50]	[34]	-2	hSpCas9	negative selection	11805344
78294531	78294554	5	-	28162770	MONOMAC1	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.10791095658657002	[203]	[216]	-1	hSpCas9	negative selection	11974701
78162834	78162857	5	+	28162770	MONOMAC1	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.13765829998062196	[237]	[247]	-1	hSpCas9	negative selection	11974702
78181506	78181529	5	-	28162770	MONOMAC1	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	0.25713904612624827	[199]	[273]	2	hSpCas9	negative selection	11974703
78128074	78128097	5	-	28162770	MONOMAC1	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.36292164753170814	[96]	[142]	3	hSpCas9	negative selection	11974704
78113758	78113781	5	-	28162770	MONOMAC1	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.47615283667333763	[73]	[117]	5	hSpCas9	negative selection	11974705
78294460	78294483	5	+	28162770	MONOMAC1	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.4764192469808313	[141]	[116]	-4	hSpCas9	negative selection	11974706
78129123	78129146	5	+	28162770	MONOMAC1	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.45831498155300054	[119]	[188]	4	hSpCas9	negative selection	11974707
78113876	78113899	5	-	28162770	MONOMAC1	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.08456211780114109	[36]	[39]	0	hSpCas9	negative selection	11974708
78015463	78015486	5	+	28162770	MONOMAC1	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	0.34979052477483136	[114]	[167]	3	hSpCas9	negative selection	11974709
78267529	78267552	5	-	28162770	MONOMAC1	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.41963451338894053	[29]	[45]	4	hSpCas9	negative selection	11974710
78294531	78294554	5	-	28162770	OCIAML2	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	-0.7882015150853876	[61]	[198]	-5	hSpCas9	negative selection	12144067
78162834	78162857	5	+	28162770	OCIAML2	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	0.8323567059917409	[45]	[453]	7	hSpCas9	negative selection	12144068
78181506	78181529	5	-	28162770	OCIAML2	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.09960718082662928	[51]	[268]	-1	hSpCas9	negative selection	12144069
78128074	78128097	5	-	28162770	OCIAML2	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	-0.30070482379984903	[25]	[116]	-2	hSpCas9	negative selection	12144070
78113758	78113781	5	-	28162770	OCIAML2	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	-0.2449170456141019	[30]	[144]	-2	hSpCas9	negative selection	12144071
78294460	78294483	5	+	28162770	OCIAML2	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	0.05483166373033316	[32]	[189]	0	hSpCas9	negative selection	12144072
78129123	78129146	5	+	28162770	OCIAML2	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.2546539638764097	[30]	[204]	2	hSpCas9	negative selection	12144073
78113876	78113899	5	-	28162770	OCIAML2	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	0.37067242873878037	[5]	[42]	3	hSpCas9	negative selection	12144074
78015463	78015486	5	+	28162770	OCIAML2	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.1409243797630796	[36]	[185]	-1	hSpCas9	negative selection	12144075
78267529	78267552	5	-	28162770	OCIAML2	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.6846484002357498	[10]	[97]	6	hSpCas9	negative selection	12144076
78294531	78294554	5	-	28162770	OCIAML3	viability	TGAGCAGTCCGGAGGAGGGGAGG	AP3B1	ENSG00000132842	0.07534704768736533	[82]	[263]	0	hSpCas9	negative selection	12313433
78162834	78162857	5	+	28162770	OCIAML3	viability	GCAGACAGACCAAGCCATTGAGG	AP3B1	ENSG00000132842	-0.7866527182665592	[79]	[139]	-5	hSpCas9	negative selection	12313434
78181506	78181529	5	-	28162770	OCIAML3	viability	GCTTCAGAGCAGGAATGCTGCGG	AP3B1	ENSG00000132842	-0.10722553354191028	[75]	[212]	-1	hSpCas9	negative selection	12313435
78128074	78128097	5	-	28162770	OCIAML3	viability	GGAATTATCTAATTGGCCAGAGG	AP3B1	ENSG00000132842	0.03675855001011785	[30]	[95]	0	hSpCas9	negative selection	12313436
78113758	78113781	5	-	28162770	OCIAML3	viability	AAGAGGAACTCAAAAGCCAAAGG	AP3B1	ENSG00000132842	0.16604156695508432	[30]	[104]	1	hSpCas9	negative selection	12313437
78294460	78294483	5	+	28162770	OCIAML3	viability	ATCGCTGCTAAAGAGGCCGAAGG	AP3B1	ENSG00000132842	-0.9996464416007573	[50]	[76]	-6	hSpCas9	negative selection	12313438
78129123	78129146	5	+	28162770	OCIAML3	viability	TTAAAAGGAGACTCAAGCAGTGG	AP3B1	ENSG00000132842	0.6853285778387311	[54]	[266]	6	hSpCas9	negative selection	12313439
78113876	78113899	5	-	28162770	OCIAML3	viability	AGAACAAGGCGAAAGTGGGGAGG	AP3B1	ENSG00000132842	-0.9159357352115254	[14]	[23]	-6	hSpCas9	negative selection	12313440
78015463	78015486	5	+	28162770	OCIAML3	viability	AACCTTCTGAAAGATCACAGAGG	AP3B1	ENSG00000132842	-0.24442320253393535	[61]	[157]	-2	hSpCas9	negative selection	12313441
78267529	78267552	5	-	28162770	OCIAML3	viability	CTAAACTGGATGCTATGAAGCGG	AP3B1	ENSG00000132842	0.018969236566589665	[16]	[51]	0	hSpCas9	negative selection	12313442