Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 348
• Symbol: APOE
• Description: apolipoprotein E

DataSource: http://genomecrispr.dkfz.de/#!/results/APOE

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
44907767	44907790	19	+	26472758	Jiyoye	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.7179629187880354	[103]	[128]	5	hSpCas9	negative selection	8439
44907826	44907849	19	+	26472758	Jiyoye	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	8440
44907878	44907901	19	-	26472758	Jiyoye	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.11283167737451294	[75]	[52]	-1	hSpCas9	negative selection	8441
44907893	44907916	19	+	26472758	Jiyoye	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	0.35406404504631106	[82]	[79]	2	hSpCas9	negative selection	8442
44907865	44907888	19	+	26472758	Jiyoye	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	2.1330004180668793	[25]	[85]	9	hSpCas9	negative selection	8443
44907752	44907775	19	+	26472758	Jiyoye	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.5115120413206091	[279]	[300]	4	hSpCas9	negative selection	8444
44907839	44907862	19	-	26472758	Jiyoye	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.31971254025553386	[50]	[47]	2	hSpCas9	negative selection	8445
44906617	44906640	19	+	26472758	Jiyoye	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.3501444364694945	[128]	[123]	2	hSpCas9	negative selection	8446
44907779	44907802	19	+	26472758	Jiyoye	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	0.3724099633451967	[41]	[40]	3	hSpCas9	negative selection	8447
44907931	44907954	19	+	26472758	Jiyoye	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	-1.2593170047118811	[272]	[85]	-7	hSpCas9	negative selection	8448
44907767	44907790	19	+	26472758	KBM7	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.25339644708549425	[456,343]	[175,138]	-2	hSpCas9	negative selection	199557
44907826	44907849	19	+	26472758	KBM7	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	1.0816969781589814	[0,0]	[0,0]	9	hSpCas9	negative selection	199558
44907878	44907901	19	-	26472758	KBM7	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.06572112294812338	[280,219]	[115,127]	0	hSpCas9	negative selection	199559
44907893	44907916	19	+	26472758	KBM7	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.7665123392552478	[544,501]	[195,98]	-6	hSpCas9	negative selection	199560
44907865	44907888	19	+	26472758	KBM7	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.129513217371021	[483,255]	[142,222]	1	hSpCas9	negative selection	199561
44907752	44907775	19	+	26472758	KBM7	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.887710716705684	[1014,569]	[842,520]	8	hSpCas9	negative selection	199562
44907839	44907862	19	-	26472758	KBM7	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.6008886379816438	[338,268]	[190,236]	6	hSpCas9	negative selection	199563
44906617	44906640	19	+	26472758	KBM7	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.02647451358270963	[432,533]	[213,237]	0	hSpCas9	negative selection	199564
44907779	44907802	19	+	26472758	KBM7	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.7650544479400525	[270,224]	[90,47]	-6	hSpCas9	negative selection	199565
44907931	44907954	19	+	26472758	KBM7	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.07575106584778252	[489,535]	[178,325]	0	hSpCas9	negative selection	199566
44907767	44907790	19	+	26472758	Raji	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.20876220691975686	[248]	[49]	-2	hSpCas9	negative selection	390675
44907826	44907849	19	+	26472758	Raji	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	390676
44907878	44907901	19	-	26472758	Raji	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.9223638080204526	[97]	[11]	-6	hSpCas9	negative selection	390677
44907893	44907916	19	+	26472758	Raji	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	0.3455432725683641	[155]	[45]	3	hSpCas9	negative selection	390678
44907865	44907888	19	+	26472758	Raji	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.5608951824670791	[110]	[37]	5	hSpCas9	negative selection	390679
44907752	44907775	19	+	26472758	Raji	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.9959622527051764	[295]	[136]	8	hSpCas9	negative selection	390680
44907839	44907862	19	-	26472758	Raji	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.463365106127856	[201]	[33]	-4	hSpCas9	negative selection	390681
44906617	44906640	19	+	26472758	Raji	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.21454455951376306	[299]	[59]	-2	hSpCas9	negative selection	390682
44907779	44907802	19	+	26472758	Raji	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-2.6999713866840045	[167]	[5]	-9	hSpCas9	negative selection	390683
44907931	44907954	19	+	26472758	Raji	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.1475229262268139	[318]	[81]	1	hSpCas9	negative selection	390684
44907767	44907790	19	+	26472758	K562	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.828093772117921	[407]	[193]	-5	hSpCas9	negative selection	581793
44907826	44907849	19	+	26472758	K562	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	581794
44907878	44907901	19	-	26472758	K562	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.3870231231092473	[230]	[254]	3	hSpCas9	negative selection	581795
44907893	44907916	19	+	26472758	K562	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	0.17766990981186076	[375]	[358]	1	hSpCas9	negative selection	581796
44907865	44907888	19	+	26472758	K562	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.059579052212851286	[315]	[277]	0	hSpCas9	negative selection	581797
44907752	44907775	19	+	26472758	K562	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.7266713070415451	[649]	[907]	6	hSpCas9	negative selection	581798
44907839	44907862	19	-	26472758	K562	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.5752986954088763	[292]	[165]	-4	hSpCas9	negative selection	581799
44906617	44906640	19	+	26472758	K562	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.7571363439177231	[388]	[554]	6	hSpCas9	negative selection	581800
44907779	44907802	19	+	26472758	K562	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-1.021861337671001	[355]	[147]	-5	hSpCas9	negative selection	581801
44907931	44907954	19	+	26472758	K562	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.5645970406038494	[494]	[617]	4	hSpCas9	negative selection	581802
44907839	44907862	19	+	26627737	DLD1	viability	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.11301231370988762	[429]	[142,134,155]	1	hSpCas9	negative selection	805364
44907839	44907862	19	-	26627737	DLD1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.6284877509751106	[2453]	[584,388,507]	-6	hSpCas9	negative selection	805365
44908897	44908920	19	-	26627737	DLD1	viability	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.05458365383445951	[1385]	[539,289,415]	0	hSpCas9	negative selection	805366
44909126	44909149	19	-	26627737	DLD1	viability	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.08490687756357462	[695]	[219,202,193]	-1	hSpCas9	negative selection	805367
44909150	44909173	19	-	26627737	DLD1	viability	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.453398227942329	[1376]	[338,352,260]	-4	hSpCas9	negative selection	805368
44909162	44909185	19	+	26627737	DLD1	viability	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.2879215881596906	[303]	[35,54,132]	-3	hSpCas9	negative selection	805369
44907839	44907862	19	+	26627737	GBM cells	viability after 5 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.23530002246673906	[277]	[201,148]	3	hSpCas9	negative selection	887679
44907839	44907862	19	-	26627737	GBM cells	viability after 5 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.18265992626289207	[763]	[393,327]	-3	hSpCas9	negative selection	887680
44908897	44908920	19	-	26627737	GBM cells	viability after 5 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.14723749734403868	[574]	[340,341]	2	hSpCas9	negative selection	887681
44909126	44909149	19	-	26627737	GBM cells	viability after 5 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.04598844917550693	[410]	[217,208]	0	hSpCas9	negative selection	887682
44909150	44909173	19	-	26627737	GBM cells	viability after 5 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.4062538934541007	[812]	[347,309]	-6	hSpCas9	negative selection	887683
44909162	44909185	19	+	26627737	GBM cells	viability after 5 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.6878072610957527	[190]	[148,180]	8	hSpCas9	negative selection	887684
44907839	44907862	19	+	26627737	GBM cells	viability after 13 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.2630139880746424	[277]	[144,109]	-3	hSpCas9	negative selection	969994
44907839	44907862	19	-	26627737	GBM cells	viability after 13 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.0443556452766416	[763]	[550,326]	0	hSpCas9	negative selection	969995
44908897	44908920	19	-	26627737	GBM cells	viability after 13 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.3313959737137453	[574]	[450,344]	4	hSpCas9	negative selection	969996
44909126	44909149	19	-	26627737	GBM cells	viability after 13 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.0760316950823835	[410]	[228,239]	1	hSpCas9	negative selection	969997
44909150	44909173	19	-	26627737	GBM cells	viability after 13 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.3326460348092555	[812]	[432,282]	-4	hSpCas9	negative selection	969998
44909162	44909185	19	+	26627737	GBM cells	viability after 13 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.5812776945978072	[190]	[191,124]	7	hSpCas9	negative selection	969999
44907839	44907862	19	+	26627737	GBM cells	viability after 21 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.3595515502267651	[277]	[198,188]	4	hSpCas9	negative selection	1052309
44907839	44907862	19	-	26627737	GBM cells	viability after 21 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.05916192760592587	[763]	[400,395]	0	hSpCas9	negative selection	1052310
44908897	44908920	19	-	26627737	GBM cells	viability after 21 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.7915886371940648	[574]	[546,534]	7	hSpCas9	negative selection	1052311
44909126	44909149	19	-	26627737	GBM cells	viability after 21 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.7172680201461606	[410]	[399,336]	7	hSpCas9	negative selection	1052312
44909150	44909173	19	-	26627737	GBM cells	viability after 21 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-1.4554636258402849	[812]	[147,172]	-8	hSpCas9	negative selection	1052313
44909162	44909185	19	+	26627737	GBM cells	viability after 21 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.41318627659129914	[190]	[133,141]	4	hSpCas9	negative selection	1052314
44907839	44907862	19	+	26627737	RPE1	viability after 9 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.39243287994667353	[662]	[216,343]	2	hSpCas9	negative selection	1134624
44907839	44907862	19	-	26627737	RPE1	viability after 9 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.3012403194220672	[4238]	[479,613]	-7	hSpCas9	negative selection	1134625
44908897	44908920	19	-	26627737	RPE1	viability after 9 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-1.1539094196170205	[3474]	[570,382]	-7	hSpCas9	negative selection	1134626
44909126	44909149	19	-	26627737	RPE1	viability after 9 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	1.26810677424027	[558]	[448,385]	7	hSpCas9	negative selection	1134627
44909150	44909173	19	-	26627737	RPE1	viability after 9 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.610447137591617	[1094]	[308,799]	4	hSpCas9	negative selection	1134628
44909162	44909185	19	+	26627737	RPE1	viability after 9 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.9960331176360859	[1175]	[198,165]	-6	hSpCas9	negative selection	1134629
44907839	44907862	19	+	26627737	RPE1	viability after 12 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.1301538355765101	[662]	[226,160]	0	hSpCas9	negative selection	1216939
44907839	44907862	19	-	26627737	RPE1	viability after 12 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.8513781417757829	[4238]	[655,604]	-5	hSpCas9	negative selection	1216940
44908897	44908920	19	-	26627737	RPE1	viability after 12 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-1.2390998562209687	[3474]	[429,358]	-7	hSpCas9	negative selection	1216941
44909126	44909149	19	-	26627737	RPE1	viability after 12 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	1.14940408997284	[558]	[405,255]	7	hSpCas9	negative selection	1216942
44909150	44909173	19	-	26627737	RPE1	viability after 12 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.7175780135580561	[1094]	[390,581]	4	hSpCas9	negative selection	1216943
44909162	44909185	19	+	26627737	RPE1	viability after 12 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-1.175161469399427	[1175]	[102,178]	-7	hSpCas9	negative selection	1216944
44907839	44907862	19	+	26627737	RPE1	viability after 15 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.30033609593521715	[662]	[317,146]	2	hSpCas9	negative selection	1299254
44907839	44907862	19	-	26627737	RPE1	viability after 15 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.5795360226333592	[4238]	[332,466]	-7	hSpCas9	negative selection	1299255
44908897	44908920	19	-	26627737	RPE1	viability after 15 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-1.273872611505483	[3474]	[517,298]	-7	hSpCas9	negative selection	1299256
44909126	44909149	19	-	26627737	RPE1	viability after 15 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.47831674642067595	[558]	[231,208]	3	hSpCas9	negative selection	1299257
44909150	44909173	19	-	26627737	RPE1	viability after 15 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	1.149698789033618	[1094]	[701,672]	6	hSpCas9	negative selection	1299258
44909162	44909185	19	+	26627737	RPE1	viability after 15 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.6720800129838226	[1175]	[192,223]	-4	hSpCas9	negative selection	1299259
44907839	44907862	19	+	26627737	RPE1	viability after 18 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.6107620235561828	[662]	[308,234]	4	hSpCas9	negative selection	1381569
44907839	44907862	19	-	26627737	RPE1	viability after 18 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.0382696477795417	[4238]	[469,649]	-6	hSpCas9	negative selection	1381570
44908897	44908920	19	-	26627737	RPE1	viability after 18 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-1.091349781084987	[3474]	[472,404]	-6	hSpCas9	negative selection	1381571
44909126	44909149	19	-	26627737	RPE1	viability after 18 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	1.0641890607159483	[558]	[371,254]	6	hSpCas9	negative selection	1381572
44909150	44909173	19	-	26627737	RPE1	viability after 18 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.7500964187205048	[1094]	[409,589]	4	hSpCas9	negative selection	1381573
44909162	44909185	19	+	26627737	RPE1	viability after 18 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-2.2309111469737255	[1175]	[128,1]	-8	hSpCas9	negative selection	1381574
44907839	44907862	19	+	26627737	HeLa	viability after 8 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.2314428345676564	[349]	[219,117,74]	-2	hSpCas9	negative selection	1463884
44907839	44907862	19	-	26627737	HeLa	viability after 8 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.1614671577721163	[1795]	[959,720,487]	-1	hSpCas9	negative selection	1463885
44908897	44908920	19	-	26627737	HeLa	viability after 8 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.4087673781377663	[778]	[339,538,446]	4	hSpCas9	negative selection	1463886
44909126	44909149	19	-	26627737	HeLa	viability after 8 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.06379129071744605	[609]	[413,224,226]	0	hSpCas9	negative selection	1463887
44909150	44909173	19	-	26627737	HeLa	viability after 8 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.32352508315850104	[1035]	[791,600,363]	3	hSpCas9	negative selection	1463888
44909162	44909185	19	+	26627737	HeLa	viability after 8 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.07235530192567022	[426]	[232,124,183]	0	hSpCas9	negative selection	1463889
44907839	44907862	19	+	26627737	HeLa	viability after 12 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	1.0771973218457491	[349]	[394,202,330]	7	hSpCas9	negative selection	1546199
44907839	44907862	19	-	26627737	HeLa	viability after 12 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.7542392420353017	[1795]	[251,530,521]	-6	hSpCas9	negative selection	1546200
44908897	44908920	19	-	26627737	HeLa	viability after 12 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.65384780525677	[778]	[465,594,447]	5	hSpCas9	negative selection	1546201
44909126	44909149	19	-	26627737	HeLa	viability after 12 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.18290093259808204	[609]	[295,302,257]	1	hSpCas9	negative selection	1546202
44909150	44909173	19	-	26627737	HeLa	viability after 12 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.43950753991930624	[1035]	[714,502,535]	4	hSpCas9	negative selection	1546203
44909162	44909185	19	+	26627737	HeLa	viability after 12 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.19934704771196182	[426]	[420,109,92]	1	hSpCas9	negative selection	1546204
44907839	44907862	19	+	26627737	HeLa	viability after 15 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.45832134366625055	[349]	[185,77,333]	4	hSpCas9	negative selection	1628514
44907839	44907862	19	-	26627737	HeLa	viability after 15 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.2986094174231695	[1795]	[496,579,716]	-3	hSpCas9	negative selection	1628515
44908897	44908920	19	-	26627737	HeLa	viability after 15 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.5665331611379831	[778]	[290,315,831]	4	hSpCas9	negative selection	1628516
44909126	44909149	19	-	26627737	HeLa	viability after 15 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.4051638165769105	[609]	[438,387,143]	3	hSpCas9	negative selection	1628517
44909150	44909173	19	-	26627737	HeLa	viability after 15 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.4222458184872855	[1035]	[419,474,821]	3	hSpCas9	negative selection	1628518
44909162	44909185	19	+	26627737	HeLa	viability after 15 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.9061216766878344	[426]	[464,238,266]	7	hSpCas9	negative selection	1628519
44907839	44907862	19	+	26627737	HeLa	viability after 18 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.4079392494485016	[349]	[112,62,333]	3	hSpCas9	negative selection	1710829
44907839	44907862	19	-	26627737	HeLa	viability after 18 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.30922210869715294	[1795]	[329,473,716]	-3	hSpCas9	negative selection	1710830
44908897	44908920	19	-	26627737	HeLa	viability after 18 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.566570344864203	[778]	[198,256,831]	4	hSpCas9	negative selection	1710831
44909126	44909149	19	-	26627737	HeLa	viability after 18 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.38203325455857806	[609]	[286,317,143]	3	hSpCas9	negative selection	1710832
44909150	44909173	19	-	26627737	HeLa	viability after 18 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.39594953311614356	[1035]	[266,386,821]	3	hSpCas9	negative selection	1710833
44909162	44909185	19	+	26627737	HeLa	viability after 18 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.9409458031863833	[426]	[324,200,266]	7	hSpCas9	negative selection	1710834
44907839	44907862	19	+	26627737	HCT116	viability after 6 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	1.1517416241039335	[804]	[431,197]	6	hSpCas9	negative selection	1793144
44907839	44907862	19	-	26627737	HCT116	viability after 6 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.28491234660410125	[3204]	[395,733]	1	hSpCas9	negative selection	1793145
44908897	44908920	19	-	26627737	HCT116	viability after 6 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.7072788479952532	[1399]	[553,251]	4	hSpCas9	negative selection	1793146
44909126	44909149	19	-	26627737	HCT116	viability after 6 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.9860989632463617	[1294]	[105,100]	-5	hSpCas9	negative selection	1793147
44909150	44909173	19	-	26627737	HCT116	viability after 6 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.9134048541140009	[2042]	[379,54]	-5	hSpCas9	negative selection	1793148
44909162	44909185	19	+	26627737	HCT116	viability after 6 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	2.0893666291648323	[747]	[1046,198]	8	hSpCas9	negative selection	1793149
44907839	44907862	19	+	26627737	HCT116	viability after 8 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.3817173269526969	[362]	[127,86,243]	-4	hSpCas9	negative selection	1875459
44907839	44907862	19	-	26627737	HCT116	viability after 8 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.7431645704065142	[1633]	[593,669,352]	-7	hSpCas9	negative selection	1875460
44908897	44908920	19	-	26627737	HCT116	viability after 8 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.25942897642597496	[897]	[367,429,440]	-3	hSpCas9	negative selection	1875461
44909126	44909149	19	-	26627737	HCT116	viability after 8 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.5098047526837749	[425]	[438,266,298]	5	hSpCas9	negative selection	1875462
44909150	44909173	19	-	26627737	HCT116	viability after 8 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.1378566709970932	[837]	[568,425,529]	1	hSpCas9	negative selection	1875463
44909162	44909185	19	+	26627737	HCT116	viability after 8 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.2681197749388357	[284]	[242,192,132]	3	hSpCas9	negative selection	1875464
44907839	44907862	19	+	26627737	HCT116	viability after 9 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.8774587741279518	[804]	[228,525]	6	hSpCas9	negative selection	1957774
44907839	44907862	19	-	26627737	HCT116	viability after 9 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.10080874626530223	[3204]	[749,835]	0	hSpCas9	negative selection	1957775
44908897	44908920	19	-	26627737	HCT116	viability after 9 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.9164007150469593	[1399]	[890,558]	6	hSpCas9	negative selection	1957776
44909126	44909149	19	-	26627737	HCT116	viability after 9 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.49098570019996157	[1294]	[490,481]	3	hSpCas9	negative selection	1957777
44909150	44909173	19	-	26627737	HCT116	viability after 9 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.19192262356972933	[2042]	[619,364]	-1	hSpCas9	negative selection	1957778
44909162	44909185	19	+	26627737	HCT116	viability after 9 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.28590000170506136	[747]	[314,186]	2	hSpCas9	negative selection	1957779
44907839	44907862	19	+	26627737	HCT116	viability after 12 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.4099666455785033	[362]	[167,77,180]	-4	hSpCas9	negative selection	2040089
44907839	44907862	19	-	26627737	HCT116	viability after 12 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.29259663603784913	[1633]	[733,521,839]	-3	hSpCas9	negative selection	2040090
44908897	44908920	19	-	26627737	HCT116	viability after 12 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.3809273899523715	[897]	[394,305,381]	-4	hSpCas9	negative selection	2040091
44909126	44909149	19	-	26627737	HCT116	viability after 12 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.14976793241376102	[425]	[202,230,171]	-1	hSpCas9	negative selection	2040092
44909150	44909173	19	-	26627737	HCT116	viability after 12 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.30520465100757677	[837]	[537,503,589]	3	hSpCas9	negative selection	2040093
44909162	44909185	19	+	26627737	HCT116	viability after 12 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.25287340289951016	[284]	[270,166,88]	2	hSpCas9	negative selection	2040094
44907839	44907862	19	+	26627737	HCT116	viability after 15 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.2524435679303179	[362]	[126,119,270]	-3	hSpCas9	negative selection	2122404
44907839	44907862	19	-	26627737	HCT116	viability after 15 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.5103817483224571	[1633]	[710,718,553]	-5	hSpCas9	negative selection	2122405
44908897	44908920	19	-	26627737	HCT116	viability after 15 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.6152160857629051	[897]	[539,176,317]	-6	hSpCas9	negative selection	2122406
44909126	44909149	19	-	26627737	HCT116	viability after 15 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.4419964475373932	[425]	[543,244,234]	4	hSpCas9	negative selection	2122407
44909150	44909173	19	-	26627737	HCT116	viability after 15 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.09713941958441485	[837]	[589,490,472]	1	hSpCas9	negative selection	2122408
44909162	44909185	19	+	26627737	HCT116	viability after 15 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.5893047485000433	[284]	[316,236,193]	5	hSpCas9	negative selection	2122409
44907839	44907862	19	+	26627737	HCT116	viability after 18 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.47834294364452823	[362]	[107,123,146]	-4	hSpCas9	negative selection	2204719
44907839	44907862	19	-	26627737	HCT116	viability after 18 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.5895959124615429	[1633]	[678,254,664]	-5	hSpCas9	negative selection	2204720
44908897	44908920	19	-	26627737	HCT116	viability after 18 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.6261440435608113	[897]	[235,289,318]	-5	hSpCas9	negative selection	2204721
44909126	44909149	19	-	26627737	HCT116	viability after 18 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.13216387083407777	[425]	[258,190,109]	-1	hSpCas9	negative selection	2204722
44909150	44909173	19	-	26627737	HCT116	viability after 18 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	0.05765334812396605	[837]	[449,323,500]	0	hSpCas9	negative selection	2204723
44909162	44909185	19	+	26627737	HCT116	viability after 18 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.4209806880642222	[284]	[329,93,132]	3	hSpCas9	negative selection	2204724
44907768	44907790	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	1.2261579149327573	[1068,1247,911]	[0,0,0]	4	hSpCas9	positive selection	2380514
44907777	44907802	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GAGCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	1.0226430873314825	[975,1451,1270]	[0,0,0]	3	hSpCas9	positive selection	2380515
44907808	44907831	19	+	24717434	HeLa	essential genes for diphteria toxin toxicity	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	1.6755929552910382	[965,509,901]	[0,0,0]	5	hSpCas9	positive selection	2380516
44907768	44907790	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	1.2252173539277287	[1068,1247,911]	[0,0,0]	3	hSpCas9	positive selection	2381609
44907777	44907802	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	1.0221363860071548	[975,1451,1270]	[0,0,0]	2	hSpCas9	positive selection	2381610
44907808	44907831	19	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	1.6765652324703548	[965,509,901]	[0,0,0]	4	hSpCas9	positive selection	2381611
44908693	44908716	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.6635637174645879	[1,1]	[1,0]	-7	hSpCas9	positive selection	2971013
44908704	44908727	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	-0.3351680808291688	[2,3]	[2,1]	-5	hSpCas9	positive selection	2971014
44908627	44908650	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	0.21873503535020206	[3,3]	[2,4]	4	hSpCas9	positive selection	2971015
44908688	44908711	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	-1.146388427247556	[1,2]	[0,0]	-9	hSpCas9	positive selection	2971016
44908693	44908716	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.49871284885556305	[1,1]	[1,1]	8	hSpCas9	positive selection	3038871
44908704	44908727	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	-0.21782104711459785	[2,2]	[3,0]	-3	hSpCas9	positive selection	3038872
44908627	44908650	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	-0.3384367792413544	[3,3]	[2,1]	-5	hSpCas9	positive selection	3038873
44908688	44908711	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	-0.14170625586352348	[1,1]	[2,0]	-2	hSpCas9	positive selection	3038874
44909234	44909257		-	24336571	A375	resistance to PLX after 7 days	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.059794028731952886	[11,9]	[11,9]	2	hSpCas9	positive selection	3124108
44907769	44907792		-	24336571	A375	resistance to PLX after 7 days	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	0.31075413817125525	[17,14]	[21,18]	8	hSpCas9	positive selection	3124117
44907865	44907888		+	24336571	A375	resistance to PLX after 7 days	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.1952301058684055	[6,6]	[4,6]	-6	hSpCas9	positive selection	3124128
44909234	44909257		-	24336571	A375	resistance to PLX after 14 days	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.17245485145782685	[9,11]	[4,5]	1	hSpCas9	positive selection	3181901
44907769	44907792		-	24336571	A375	resistance to PLX after 14 days	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	-0.19454644327569437	[23,12]	[6,7]	-2	hSpCas9	positive selection	3181910
44907865	44907888		+	24336571	A375	resistance to PLX after 14 days	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	1.8122664023684947	[7,3]	[2,17]	9	hSpCas9	positive selection	3181921
44909234	44909257		-	24336571	A375	viability after 7 days	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.036511901436135946	[10]	[11,9]	0	hSpCas9	negative selection	3239694
44907769	44907792		-	24336571	A375	viability after 7 days	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	-0.26257970409734127	[20]	[17,14]	-4	hSpCas9	negative selection	3239703
44907865	44907888		+	24336571	A375	viability after 7 days	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.8371919161473118	[13]	[6,6]	-8	hSpCas9	negative selection	3239714
44909234	44909257		-	24336571	A375	viability after 14 days	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.0781365905325613	[10]	[9,11]	1	hSpCas9	negative selection	3297487
44907769	44907792		-	24336571	A375	viability after 14 days	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	-0.06621955741887542	[20]	[23,12]	0	hSpCas9	negative selection	3297496
44907865	44907888		+	24336571	A375	viability after 14 days	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.9523567828129137	[13]	[7,3]	-8	hSpCas9	negative selection	3297507
44909234	44909257	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	-0.21692318334470412	[149,205]	[0,0]	-1	hSpCas9	positive selection	3337070
44908692	44908715	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	5.929751553417331	[3,0]	[0,0]	9	hSpCas9	positive selection	3337071
44907815	44907838	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.21880166075690144	[125,136]	[0,0]	1	hSpCas9	positive selection	3337072
44906642	44906665	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-1.6374915518621085	[475,475]	[0,0]	-9	hSpCas9	positive selection	3356316
44907878	44907901	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.4841407749553118	[213,213]	[0,0]	-3	hSpCas9	positive selection	3356317
44906617	44906640	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	1.5568864933047428	[51,51]	[0,0]	6	hSpCas9	positive selection	3356318
44908692	44908715	19	+	26780180	HT29	viability (Avana library 4 designs)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.14076525038168	[]	[]	4	hSpCas9	negative selection	3407121
44908704	44908727	19	-	26780180	HT29	viability (Avana library 4 designs)	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	0.370624652163415	[]	[]	1	hSpCas9	negative selection	3407122
44908626	44908649	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	2.21418893337635	[]	[]	7	hSpCas9	negative selection	3407123
44908687	44908710	19	+	26780180	HT29	viability (Avana library 4 designs)	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	2.11020031365671	[]	[]	7	hSpCas9	negative selection	3407124
44908704	44908727	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	3.10253463796158	[]	[]	5	hSpCas9	negative selection	3480013
44908687	44908710	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	4.2844852364222	[]	[]	7	hSpCas9	negative selection	3480014
44908626	44908649	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	2.56939247333737	[]	[]	4	hSpCas9	negative selection	3480015
44908692	44908715	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	9.26541870215164	[]	[]	9	hSpCas9	negative selection	3480016
44907923	44907946	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAGCTCCCAGGTCACCCAGG	APOE	ENSG00000130203	2.3969091846545	[]	[]	3	hSpCas9	negative selection	3480017
44907808	44907831	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	3.98004690979469	[]	[]	6	hSpCas9	negative selection	3480018
44908704	44908727	19	-	26780180	A375	viability (Avana lentiGuide)	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	5.3270475672335	[]	[]	5	hSpCas9	negative selection	3588672
44908687	44908710	19	+	26780180	A375	viability (Avana lentiGuide)	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	2.59695765983522	[]	[]	2	hSpCas9	negative selection	3588673
44908626	44908649	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	0.829910663086036	[]	[]	1	hSpCas9	negative selection	3588674
44908692	44908715	19	+	26780180	A375	viability (Avana lentiGuide)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.754320812914499	[]	[]	-1	hSpCas9	negative selection	3588675
44907923	44907946	19	+	26780180	A375	viability (Avana lentiGuide)	GCTCAGCTCCCAGGTCACCCAGG	APOE	ENSG00000130203	-2.16712537504461	[]	[]	-4	hSpCas9	negative selection	3588676
44907808	44907831	19	+	26780180	A375	viability (Avana lentiGuide)	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	1.41118532122296	[]	[]	1	hSpCas9	negative selection	3588677
44908704	44908727	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	0.18775358958566207	[4]	[5,5]	5	hSpCas9	positive selection	3697331
44908687	44908710	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	0.26766403514482046	[3]	[5,4]	7	hSpCas9	positive selection	3697332
44908626	44908649	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	0.19479852585267132	[4]	[5,5]	5	hSpCas9	positive selection	3697333
44908692	44908715	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5168591961138085	[3]	[5,5]	9	hSpCas9	positive selection	3697334
44907923	44907946	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAGCTCCCAGGTCACCCAGG	APOE	ENSG00000130203	0.24236616884011145	[4]	[5,4]	7	hSpCas9	positive selection	3697335
44907808	44907831	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	0.2480470438575397	[4]	[5,4]	7	hSpCas9	positive selection	3697336
44908704	44908727	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGGCCTGCACCTCGCCGCGG	APOE	ENSG00000130203	-0.04706078230911246	[5]	[5,3]	0	hSpCas9	positive selection	3805938
44908687	44908710	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCGCCTGGTGCAGTACCGCGG	APOE	ENSG00000130203	-0.22452971975538646	[5]	[4,2]	-3	hSpCas9	positive selection	3805939
44908626	44908649	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTCCAAGGAGCTGCAGGCGG	APOE	ENSG00000130203	-0.2263410970699216	[5]	[2,4]	-3	hSpCas9	positive selection	3805940
44908692	44908715	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.35129701623847653	[3]	[2,0]	-5	hSpCas9	positive selection	3805941
44907923	44907946	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAGCTCCCAGGTCACCCAGG	APOE	ENSG00000130203	0.31776252803806454	[5]	[6,6]	8	hSpCas9	positive selection	3805942
44907808	44907831	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGCGCCAGCAGACCGAGTGG	APOE	ENSG00000130203	0.007835104274424631	[4]	[4,2]	0	hSpCas9	positive selection	3805943
44907878	44907901	19	-	26780180	A375	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	1.26414492325726	[]	[]	6	hSpCas9	negative selection	3914199
44908692	44908715	19	+	26780180	A375	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.293782148044371	[]	[]	0	hSpCas9	negative selection	3914200
44907815	44907838	19	-	26780180	A375	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.825307281649235	[]	[]	3	hSpCas9	negative selection	3914201
44909234	44909257	19	-	26780180	A375	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	1.18553308892134	[]	[]	6	hSpCas9	negative selection	3914202
44906617	44906640	19	+	26780180	A375	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.745907946627962	[]	[]	2	hSpCas9	negative selection	3914203
44906642	44906665	19	+	26780180	A375	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	1.48133823207883	[]	[]	8	hSpCas9	negative selection	3914204
44907878	44907901	19	-	26780180	HT29	viability (GeCKOv2 library)	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	1.39447555537443	[]	[]	7	hSpCas9	negative selection	4022165
44908692	44908715	19	+	26780180	HT29	viability (GeCKOv2 library)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.0150336041457485	[]	[]	0	hSpCas9	negative selection	4022166
44907815	44907838	19	-	26780180	HT29	viability (GeCKOv2 library)	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.41976628280429	[]	[]	1	hSpCas9	negative selection	4022167
44909234	44909257	19	-	26780180	HT29	viability (GeCKOv2 library)	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	1.00120909303283	[]	[]	4	hSpCas9	negative selection	4022168
44906617	44906640	19	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.605894259755099	[]	[]	2	hSpCas9	negative selection	4022169
44906642	44906665	19	+	26780180	HT29	viability (GeCKOv2 library)	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	1.72260281578826	[]	[]	8	hSpCas9	negative selection	4022170
44909234	44909257	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	-0.014622954229663983	[3]	[2,2]	0	hSpCas9	positive selection	4148114
44907769	44907792	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	0.240987307061762	[3]	[3,2]	6	hSpCas9	positive selection	4148125
44907865	44907888	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.20867945943048613	[3]	[2,2]	5	hSpCas9	positive selection	4148136
44909234	44909257	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.9353418122882674	[2]	[0,0,0,4]	6	hSpCas9	positive selection	4212136
44907769	44907792	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCCACCGCTTGCTCCACCTTGG	APOE	ENSG00000130203	0.8462037503383504	[4]	[3,2,3,3]	5	hSpCas9	positive selection	4212147
44907865	44907888	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.5418027704214086	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4212158
44909234	44909257	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.0997962823480282	[3]	[3,2]	2	hSpCas9	positive selection	4256219
44908692	44908715	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.2628736219225598	[0]	[1,0]	5	hSpCas9	positive selection	4256220
44907815	44907838	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	-0.4787051615916808	[2]	[2,0]	-8	hSpCas9	positive selection	4256221
44906642	44906665	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.1972633470072787	[4]	[3,2]	-4	hSpCas9	positive selection	4320503
44907878	44907901	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.04628745154662692	[3]	[2,2]	0	hSpCas9	positive selection	4320504
44906617	44906640	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.006068237224689743	[1]	[1,0]	0	hSpCas9	positive selection	4320505
44907866	44907888	19	+	27760321	OCIAML3	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.360228170567321	[866,689]	[345,634]	-4	hSpCas9	negative selection	4378769
44908567	44908589	19	+	27760321	OCIAML3	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.47845450084780616	[540,463]	[564,520]	6	hSpCas9	negative selection	4378770
44908693	44908715	19	+	27760321	OCIAML3	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.552944842066676	[729,720]	[776,909]	6	hSpCas9	negative selection	4378771
44908824	44908846	19	-	27760321	OCIAML3	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.5502889328740865	[870,663]	[747,1033]	6	hSpCas9	negative selection	4378772
44908914	44908936	19	-	27760321	OCIAML3	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.017770381916126454	[901,674]	[585,661]	0	hSpCas9	negative selection	4378773
44907866	44907888	19	+	27760321	OCIAML2	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.04174098400208037	[866,689]	[510,819]	0	hSpCas9	negative selection	4462232
44908567	44908589	19	+	27760321	OCIAML2	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	-0.17771365124483784	[540,463]	[312,417]	-2	hSpCas9	negative selection	4462233
44908693	44908715	19	+	27760321	OCIAML2	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5144744967476256	[729,720]	[696,1029]	7	hSpCas9	negative selection	4462234
44908824	44908846	19	-	27760321	OCIAML2	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.4807508550053672	[870,663]	[740,1015]	6	hSpCas9	negative selection	4462235
44908914	44908936	19	-	27760321	OCIAML2	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.38291189702030337	[901,674]	[727,951]	5	hSpCas9	negative selection	4462236
44907866	44907888	19	+	27760321	MV411	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.057097951863344765	[866,689]	[338,819]	0	hSpCas9	negative selection	4545695
44908567	44908589	19	+	27760321	MV411	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	-0.20517797802258964	[540,463]	[257,329]	-1	hSpCas9	negative selection	4545696
44908693	44908715	19	+	27760321	MV411	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.25374059716218433	[729,720]	[336,925]	1	hSpCas9	negative selection	4545697
44908824	44908846	19	-	27760321	MV411	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.0560245536962114	[870,663]	[316,830]	0	hSpCas9	negative selection	4545698
44908914	44908936	19	-	27760321	MV411	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.506416335184837	[901,674]	[773,670]	3	hSpCas9	negative selection	4545699
44907866	44907888	19	+	27760321	HL60	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.07763163524593819	[866,689]	[531,669]	-1	hSpCas9	negative selection	4629158
44908567	44908589	19	+	27760321	HL60	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	1.1142791613110472	[540,463]	[685,1097]	9	hSpCas9	negative selection	4629159
44908693	44908715	19	+	27760321	HL60	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.4159275452519311	[729,720]	[854,726]	5	hSpCas9	negative selection	4629160
44908824	44908846	19	-	27760321	HL60	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.24170486948185976	[870,663]	[603,874]	3	hSpCas9	negative selection	4629161
44908914	44908936	19	-	27760321	HL60	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	-0.00989610945090369	[901,674]	[542,730]	0	hSpCas9	negative selection	4629162
44907866	44907888	19	+	27760321	HT1080	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.7458842303232031	[689,538]	[516,293]	4	hSpCas9	negative selection	4712621
44908567	44908589	19	+	27760321	HT1080	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.31566410220777036	[463,361]	[125,290]	1	hSpCas9	negative selection	4712622
44908693	44908715	19	+	27760321	HT1080	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.9729158210069315	[720,562]	[438,570]	5	hSpCas9	negative selection	4712623
44908824	44908846	19	-	27760321	HT1080	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.5580249480027117	[663,517]	[348,343]	3	hSpCas9	negative selection	4712624
44908914	44908936	19	-	27760321	HT1080	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.7580319303180459	[674,526]	[381,429]	4	hSpCas9	negative selection	4712625
44907866	44907888	19	+	27760321	HT29	viability after 7 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.5289787534750483	[689,538]	[505,358,763]	-6	hSpCas9	negative selection	4796084
44908567	44908589	19	+	27760321	HT29	viability after 7 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.22617601680411897	[463,361]	[809,541,539]	3	hSpCas9	negative selection	4796085
44908693	44908715	19	+	27760321	HT29	viability after 7 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.12086694629636019	[720,562]	[1100,782,450]	-2	hSpCas9	negative selection	4796086
44908824	44908846	19	-	27760321	HT29	viability after 7 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.976504794873049	[663,517]	[1538,1281,1662]	9	hSpCas9	negative selection	4796087
44908914	44908936	19	-	27760321	HT29	viability after 7 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.2899895897353767	[674,526]	[1140,968,756]	4	hSpCas9	negative selection	4796088
44907866	44907888	19	+	27760321	HT29	viability after 25 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-1.1774358437943069	[689,538]	[253,185,515]	-7	hSpCas9	negative selection	4879547
44908567	44908589	19	+	27760321	HT29	viability after 25 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.15424198141710865	[463,361]	[398,484,718]	1	hSpCas9	negative selection	4879548
44908693	44908715	19	+	27760321	HT29	viability after 25 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.007091258082812413	[720,562]	[524,808,907]	0	hSpCas9	negative selection	4879549
44908824	44908846	19	-	27760321	HT29	viability after 25 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.5737330030954921	[663,517]	[884,1068,1074]	6	hSpCas9	negative selection	4879550
44908914	44908936	19	-	27760321	HT29	viability after 25 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.19550530641999253	[674,526]	[699,832,835]	2	hSpCas9	negative selection	4879551
44907866	44907888	19	+	27760321	HT29	viability after 22 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-1.0266044776452987	[689,538]	[186,256,608]	-6	hSpCas9	negative selection	4963010
44908567	44908589	19	+	27760321	HT29	viability after 22 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.15743688755968754	[463,361]	[625,531,435]	1	hSpCas9	negative selection	4963011
44908693	44908715	19	+	27760321	HT29	viability after 22 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.20147295461915027	[720,562]	[461,764,714]	-2	hSpCas9	negative selection	4963012
44908824	44908846	19	-	27760321	HT29	viability after 22 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.5310104245362299	[663,517]	[762,1070,1134]	6	hSpCas9	negative selection	4963013
44908914	44908936	19	-	27760321	HT29	viability after 22 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.48769749628145076	[674,526]	[922,1037,962]	5	hSpCas9	negative selection	4963014
44907866	44907888	19	+	27760321	HT29	viability after 19 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.7906238054667879	[689,538]	[381,371,459]	-6	hSpCas9	negative selection	5046473
44908567	44908589	19	+	27760321	HT29	viability after 19 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.0723005529024578	[463,361]	[519,423,545]	0	hSpCas9	negative selection	5046474
44908693	44908715	19	+	27760321	HT29	viability after 19 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.33297228578323534	[720,562]	[684,622,455]	-3	hSpCas9	negative selection	5046475
44908824	44908846	19	-	27760321	HT29	viability after 19 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.6320036027103286	[663,517]	[1040,517,1561]	6	hSpCas9	negative selection	5046476
44908914	44908936	19	-	27760321	HT29	viability after 19 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.5670945799800883	[674,526]	[1092,1186,790]	6	hSpCas9	negative selection	5046477
44907866	44907888	19	+	27760321	HT29	viability after 16 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.6920656190535199	[689,538]	[566,386,336]	-6	hSpCas9	negative selection	5129936
44908567	44908589	19	+	27760321	HT29	viability after 16 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.4772253116599136	[463,361]	[530,448,943]	5	hSpCas9	negative selection	5129937
44908693	44908715	19	+	27760321	HT29	viability after 16 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.1589469548181196	[720,562]	[802,948,649]	1	hSpCas9	negative selection	5129938
44908824	44908846	19	-	27760321	HT29	viability after 16 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.8917142001311489	[663,517]	[1188,1438,1042]	9	hSpCas9	negative selection	5129939
44908914	44908936	19	-	27760321	HT29	viability after 16 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.6520257930002099	[674,526]	[1110,1087,974]	7	hSpCas9	negative selection	5129940
44907866	44907888	19	+	27760321	HT29	viability after 13 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-1.0464852525036554	[689,538]	[241,300,483]	-7	hSpCas9	negative selection	5213399
44908567	44908589	19	+	27760321	HT29	viability after 13 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.4959590576957085	[463,361]	[537,843,646]	6	hSpCas9	negative selection	5213400
44908693	44908715	19	+	27760321	HT29	viability after 13 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.00796438253510845	[720,562]	[648,845,727]	0	hSpCas9	negative selection	5213401
44908824	44908846	19	-	27760321	HT29	viability after 13 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	1.1133774869311603	[663,517]	[1776,1546,1145]	9	hSpCas9	negative selection	5213402
44908914	44908936	19	-	27760321	HT29	viability after 13 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.5970139291150011	[674,526]	[1381,897,892]	7	hSpCas9	negative selection	5213403
44907866	44907888	19	+	27760321	HT29	viability after 10 days	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-1.1723423752320814	[689,538]	[181,445,394]	-8	hSpCas9	negative selection	5296862
44908567	44908589	19	+	27760321	HT29	viability after 10 days	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.19944000628060832	[463,361]	[544,649,582]	2	hSpCas9	negative selection	5296863
44908693	44908715	19	+	27760321	HT29	viability after 10 days	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.2935522697139209	[720,562]	[716,606,636]	-4	hSpCas9	negative selection	5296864
44908824	44908846	19	-	27760321	HT29	viability after 10 days	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.9053808978171538	[663,517]	[1268,1432,1443]	9	hSpCas9	negative selection	5296865
44908914	44908936	19	-	27760321	HT29	viability after 10 days	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	0.38991665407626874	[674,526]	[1003,680,1249]	5	hSpCas9	negative selection	5296866
44907866	44907888	19	+	27760321	MOLM13	viability	CTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.7441247310772382	[866,689]	[411,1002]	5	hSpCas9	negative selection	5380325
44908567	44908589	19	+	27760321	MOLM13	viability	GCCTACAAATCGGAACTGGAGG	APOE	ENSG00000130203	0.7098497281227942	[540,463]	[457,465]	5	hSpCas9	negative selection	5380326
44908693	44908715	19	+	27760321	MOLM13	viability	CTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.019874721381948568	[729,720]	[440,394]	0	hSpCas9	negative selection	5380327
44908824	44908846	19	-	27760321	MOLM13	viability	CCCGGCCTGGTACACTGCCAGG	APOE	ENSG00000130203	0.24263688374595804	[870,663]	[375,620]	1	hSpCas9	negative selection	5380328
44908914	44908936	19	-	27760321	MOLM13	viability	CACAGTGGCGGCCCGCACGCGG	APOE	ENSG00000130203	-0.5819788998945705	[901,674]	[305,284]	-4	hSpCas9	negative selection	5380329
44905859	44905882	19	+	27661255	K562	viability	GGGCACGGGGATGAGCTCAGGGG	APOE	ENSG00000130203	0.1143199593140205	[892,650]	[761,593]	4	dCas9-KRAB	negative selection	5462870
44906027	44906050	19	+	27661255	K562	viability	GACCCGACCCGCTAGAAGGTGGG	APOE	ENSG00000130203	-0.37178082645010424	[567,451]	[408,236]	-7	dCas9-KRAB	negative selection	5462871
44906241	44906264	19	+	27661255	K562	viability	GAACACGGCGCTTAACTGTGAGG	APOE	ENSG00000130203	-0.19401760137446789	[188,204]	[118,152]	-6	dCas9-KRAB	negative selection	5462872
44905804	44905827	19	-	27661255	K562	viability	GACGTCCTTCACCTCCGCTGGGG	APOE	ENSG00000130203	0.009291837849917828	[2617,2399]	[2421,1677]	0	dCas9-KRAB	negative selection	5462873
44905917	44905940	19	-	27661255	K562	viability	GCTCTCCTGAGACTACCTGGAGG	APOE	ENSG00000130203	0.041712252133248695	[441,414]	[369,337]	1	dCas9-KRAB	negative selection	5462874
44909234	44909257	19	-	27260156	BXPC3	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.15031262290730762	[798]	[788,789,1048,1123]	3	hSpCas9	negative selection	5528679
44908692	44908715	19	+	27260156	BXPC3	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.11373199625003316	[30]	[23,43,6,45]	-3	hSpCas9	negative selection	5528680
44907815	44907838	19	-	27260156	BXPC3	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5226393437224205	[411]	[514,659,679,626]	9	hSpCas9	negative selection	5528681
44906642	44906665	19	+	27260156	BXPC3	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.14956357278859933	[1213]	[1073,972,1232,1331]	-3	hSpCas9	negative selection	5592963
44907878	44907901	19	-	27260156	BXPC3	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.29085744979922057	[641]	[457,511,690,543]	-6	hSpCas9	negative selection	5592964
44906617	44906640	19	+	27260156	BXPC3	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.43495860977257683	[81]	[108,131,116,102]	8	hSpCas9	negative selection	5592965
44909234	44909257	19	-	27260156	A673	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.11763873043073825	[798]	[1057,1044,1041,1016]	3	hSpCas9	negative selection	5649930
44908692	44908715	19	+	27260156	A673	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.2802092128598268	[30]	[53,47,30,48]	6	hSpCas9	negative selection	5649931
44907815	44907838	19	-	27260156	A673	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5137553592102582	[411]	[752,664,695,716]	9	hSpCas9	negative selection	5649932
44906642	44906665	19	+	27260156	A673	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.18436677503768184	[1213]	[1423,1222,1233,1264]	-4	hSpCas9	negative selection	5714214
44907878	44907901	19	-	27260156	A673	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.06690114886862941	[641]	[856,740,668,686]	-2	hSpCas9	negative selection	5714215
44906617	44906640	19	+	27260156	A673	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.20090277251219746	[81]	[95,131,79,143]	5	hSpCas9	negative selection	5714216
44909234	44909257	19	-	27260156	A375	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.4498888480362392	[798]	[1236,1193,1492,1170]	6	hSpCas9	negative selection	5771181
44908692	44908715	19	+	27260156	A375	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5244114523819059	[30]	[30,96,22,61]	7	hSpCas9	negative selection	5771182
44907815	44907838	19	-	27260156	A375	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5640682013814802	[411]	[560,1057,632,645]	8	hSpCas9	negative selection	5771183
44906642	44906665	19	+	27260156	A375	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.3240504848631751	[1213]	[1865,2149,1622,1535]	5	hSpCas9	negative selection	5835465
44907878	44907901	19	-	27260156	A375	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.178130141522103	[641]	[666,594,713,662]	-3	hSpCas9	negative selection	5835466
44906617	44906640	19	+	27260156	A375	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.4538642648294884	[81]	[116,134,116,152]	6	hSpCas9	negative selection	5835467
44909234	44909257	19	-	27260156	COLO741	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.12945691005094062	[798]	[1165,1155,1035]	2	hSpCas9	negative selection	5892432
44908692	44908715	19	+	27260156	COLO741	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.23654844130463815	[30]	[77,24,39]	5	hSpCas9	negative selection	5892433
44907815	44907838	19	-	27260156	COLO741	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.08007213326450238	[411]	[677,496,506]	1	hSpCas9	negative selection	5892434
44906642	44906665	19	+	27260156	COLO741	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.22992624677607965	[1213]	[1755,1106,1150]	-5	hSpCas9	negative selection	5956716
44907878	44907901	19	-	27260156	COLO741	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.03259813914373788	[641]	[845,888,681]	0	hSpCas9	negative selection	5956717
44906617	44906640	19	+	27260156	COLO741	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.23149213589115458	[81]	[149,153,70]	5	hSpCas9	negative selection	5956718
44909234	44909257	19	-	27260156	CAL120	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.2074835323509998	[798]	[1254,957,1244]	3	hSpCas9	negative selection	6013683
44908692	44908715	19	+	27260156	CAL120	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.3297532969406003	[30]	[40,37,64]	5	hSpCas9	negative selection	6013684
44907815	44907838	19	-	27260156	CAL120	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.6984119347307889	[411]	[1113,483,937]	8	hSpCas9	negative selection	6013685
44906642	44906665	19	+	27260156	CAL120	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.0434870855001539	[1213]	[2049,1288,1407]	0	hSpCas9	negative selection	6077967
44907878	44907901	19	-	27260156	CAL120	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.11435821832056142	[641]	[519,1259,763]	1	hSpCas9	negative selection	6077968
44906617	44906640	19	+	27260156	CAL120	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.1483995665789295	[81]	[60,134,134]	2	hSpCas9	negative selection	6077969
44909234	44909257	19	-	27260156	CADOES1	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.48106036548084885	[798]	[1115,1010,1025,993]	7	hSpCas9	negative selection	6134934
44908692	44908715	19	+	27260156	CADOES1	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.3957253479313878	[30]	[28,191,27,53]	9	hSpCas9	negative selection	6134935
44907815	44907838	19	-	27260156	CADOES1	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.7021253665724081	[411]	[584,677,500,733]	9	hSpCas9	negative selection	6134936
44906642	44906665	19	+	27260156	CADOES1	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.03162337072005683	[1213]	[1100,1008,1183,1124]	0	hSpCas9	negative selection	6199218
44907878	44907901	19	-	27260156	CADOES1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.254638786032526	[641]	[507,483,480,529]	-4	hSpCas9	negative selection	6199219
44906617	44906640	19	+	27260156	CADOES1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.04213396296802241	[81]	[66,60,49,119]	0	hSpCas9	negative selection	6199220
44909234	44909257	19	-	27260156	EWS502	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.4132509412190458	[798]	[1134,1239,995,1124]	7	hSpCas9	negative selection	6256185
44908692	44908715	19	+	27260156	EWS502	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.4363031596595186	[30]	[10,77,18,73]	7	hSpCas9	negative selection	6256186
44907815	44907838	19	-	27260156	EWS502	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.68315669432008	[411]	[587,796,660,767]	9	hSpCas9	negative selection	6256187
44906642	44906665	19	+	27260156	EWS502	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.13022597370297184	[1213]	[926,1301,1329,1161]	-2	hSpCas9	negative selection	6320469
44907878	44907901	19	-	27260156	EWS502	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.09903703334879116	[641]	[654,773,774,712]	1	hSpCas9	negative selection	6320470
44906617	44906640	19	+	27260156	EWS502	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.003332492250645025	[81]	[88,118,67,66]	0	hSpCas9	negative selection	6320471
44909234	44909257	19	-	27260156	EW8	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.4137676019954458	[798]	[955,965,803,742]	7	hSpCas9	negative selection	6377436
44908692	44908715	19	+	27260156	EW8	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.21231465354629986	[30]	[23,35,21,34]	4	hSpCas9	negative selection	6377437
44907815	44907838	19	-	27260156	EW8	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.7891620923507899	[411]	[649,554,500,620]	9	hSpCas9	negative selection	6377438
44906642	44906665	19	+	27260156	EW8	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.0074159694939286425	[1213]	[1280,880,832,974]	0	hSpCas9	negative selection	6441720
44907878	44907901	19	-	27260156	EW8	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.13897552912681815	[641]	[473,550,498,360]	-3	hSpCas9	negative selection	6441721
44906617	44906640	19	+	27260156	EW8	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.09412503621775592	[81]	[69,92,61,24]	-2	hSpCas9	negative selection	6441722
44909234	44909257	19	-	27260156	CORL105	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.1978530339929756	[798]	[1304,890,1148,969]	3	hSpCas9	negative selection	6498687
44908692	44908715	19	+	27260156	CORL105	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.6011528935789769	[30]	[52,50,103,19]	9	hSpCas9	negative selection	6498688
44907815	44907838	19	-	27260156	CORL105	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.738706152062441	[411]	[925,736,799,760]	9	hSpCas9	negative selection	6498689
44906642	44906665	19	+	27260156	CORL105	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.0902500136034452	[1213]	[1404,1142,1526,1300]	-2	hSpCas9	negative selection	6562971
44907878	44907901	19	-	27260156	CORL105	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.45587970353460616	[641]	[535,479,452,707]	-7	hSpCas9	negative selection	6562972
44906617	44906640	19	+	27260156	CORL105	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.07025869645329186	[81]	[117,86,73,84]	-1	hSpCas9	negative selection	6562973
44909234	44909257	19	-	27260156	HS294T	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.3189526726502069	[798]	[470,373,282,407]	4	hSpCas9	negative selection	6619938
44908692	44908715	19	+	27260156	HS294T	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.13736345680668727	[30]	[12,6,14,7]	-2	hSpCas9	negative selection	6619939
44907815	44907838	19	-	27260156	HS294T	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.9455502407978109	[411]	[215,264,350,423]	9	hSpCas9	negative selection	6619940
44906642	44906665	19	+	27260156	HS294T	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.1547692403540588	[1213]	[422,446,511,757]	2	hSpCas9	negative selection	6684222
44907878	44907901	19	-	27260156	HS294T	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.4663762050626605	[641]	[185,101,177,268]	-6	hSpCas9	negative selection	6684223
44906617	44906640	19	+	27260156	HS294T	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-1.0232982477925665	[81]	[15,6,21,17]	-9	hSpCas9	negative selection	6684224
44909234	44909257	19	-	27260156	HCC44	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.1842261272607707	[798]	[1312,978,1119,744]	3	hSpCas9	negative selection	6741189
44908692	44908715	19	+	27260156	HCC44	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.2298496973667934	[30]	[99,62,89,80]	9	hSpCas9	negative selection	6741190
44907815	44907838	19	-	27260156	HCC44	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5252097957055715	[411]	[746,526,838,621]	8	hSpCas9	negative selection	6741191
44906642	44906665	19	+	27260156	HCC44	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.24613591353660613	[1213]	[1774,1638,1997,1178]	4	hSpCas9	negative selection	6805473
44907878	44907901	19	-	27260156	HCC44	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.11273877423668094	[641]	[646,595,682,761]	-2	hSpCas9	negative selection	6805474
44906617	44906640	19	+	27260156	HCC44	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.1870929214538637	[81]	[162,94,147,31]	3	hSpCas9	negative selection	6805475
44909234	44909257	19	-	27260156	G402	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.4261470283704746	[798]	[1207,1176,1361,1457]	5	hSpCas9	negative selection	6862440
44908692	44908715	19	+	27260156	G402	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.46767623107726086	[30]	[57,13,69,64]	6	hSpCas9	negative selection	6862441
44907815	44907838	19	-	27260156	G402	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	1.0614666408643978	[411]	[1174,1207,1250,607]	9	hSpCas9	negative selection	6862442
44906642	44906665	19	+	27260156	G402	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.17985501703619966	[1213]	[1405,1179,1285,1357]	-2	hSpCas9	negative selection	6926724
44907878	44907901	19	-	27260156	G402	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.4454263018745369	[641]	[687,536,407,674]	-5	hSpCas9	negative selection	6926725
44906617	44906640	19	+	27260156	G402	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.6137724719544315	[81]	[303,137,190,6]	7	hSpCas9	negative selection	6926726
44909234	44909257	19	-	27260156	L33	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.1928953972824785	[798]	[856,363,633,900]	4	hSpCas9	negative selection	6983691
44908692	44908715	19	+	27260156	L33	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.12010004757355652	[30]	[69,7,22,7]	2	hSpCas9	negative selection	6983692
44907815	44907838	19	-	27260156	L33	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5336710236271487	[411]	[487,210,416,720]	9	hSpCas9	negative selection	6983693
44906642	44906665	19	+	27260156	L33	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.03845144005065548	[1213]	[1210,466,819,1331]	0	hSpCas9	negative selection	7047975
44907878	44907901	19	-	27260156	L33	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.2196107802811749	[641]	[433,276,334,564]	-5	hSpCas9	negative selection	7047976
44906617	44906640	19	+	27260156	L33	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.19431179939821108	[81]	[105,31,65,85]	4	hSpCas9	negative selection	7047977
44909234	44909257	19	-	27260156	K562	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.6675824934417861	[798]	[1042,1082,1906,528]	8	hSpCas9	negative selection	7104942
44908692	44908715	19	+	27260156	K562	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.1712577794284833	[30]	[17,52,6,20]	-2	hSpCas9	negative selection	7104943
44907815	44907838	19	-	27260156	K562	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.6239279498383907	[411]	[721,554,546,452]	7	hSpCas9	negative selection	7104944
44906642	44906665	19	+	27260156	K562	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.09841392088053302	[1213]	[1871,1146,851,833]	1	hSpCas9	negative selection	7169226
44907878	44907901	19	-	27260156	K562	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.8881069353240191	[641]	[300,544,267,146]	-7	hSpCas9	negative selection	7169227
44906617	44906640	19	+	27260156	K562	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-1.5344585739802867	[81]	[52,2,43,3]	-9	hSpCas9	negative selection	7169228
44909234	44909257	19	-	27260156	HT29	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.23838390548868438	[798]	[908,1359,1348,977]	4	hSpCas9	negative selection	7226193
44908692	44908715	19	+	27260156	HT29	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.6408447895242944	[30]	[52,49,58,69]	9	hSpCas9	negative selection	7226194
44907815	44907838	19	-	27260156	HT29	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5456964870679514	[411]	[898,764,756,537]	9	hSpCas9	negative selection	7226195
44906642	44906665	19	+	27260156	HT29	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.11615408727206988	[1213]	[1493,1471,1387,1130]	-2	hSpCas9	negative selection	7290477
44907878	44907901	19	-	27260156	HT29	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.396332541484947	[641]	[607,603,657,509]	-6	hSpCas9	negative selection	7290478
44906617	44906640	19	+	27260156	HT29	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.17624215647181085	[81]	[79,39,170,59]	-4	hSpCas9	negative selection	7290479
44909234	44909257	19	-	27260156	MHHES1	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.0075570613022134525	[798]	[1211,962,805,705]	0	hSpCas9	negative selection	7347444
44908692	44908715	19	+	27260156	MHHES1	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.6879312376166071	[30]	[106,45,46,33]	9	hSpCas9	negative selection	7347445
44907815	44907838	19	-	27260156	MHHES1	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.7886075979276025	[411]	[1083,1018,666,535]	9	hSpCas9	negative selection	7347446
44906642	44906665	19	+	27260156	MHHES1	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.10856551376232537	[1213]	[1672,1630,1284,1342]	2	hSpCas9	negative selection	7411728
44907878	44907901	19	-	27260156	MHHES1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.09910061672049963	[641]	[639,772,835,486]	-2	hSpCas9	negative selection	7411729
44906617	44906640	19	+	27260156	MHHES1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	1.0640464597381418	[81]	[218,265,196,114]	9	hSpCas9	negative selection	7411730
44909234	44909257	19	-	27260156	MEWO	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	-0.12510625932907393	[798]	[939,569,595]	-3	hSpCas9	negative selection	7468695
44908692	44908715	19	+	27260156	MEWO	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.0436176373972903	[30]	[0,44,37]	1	hSpCas9	negative selection	7468696
44907815	44907838	19	-	27260156	MEWO	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.2537328429995495	[411]	[511,410,465]	5	hSpCas9	negative selection	7468697
44906642	44906665	19	+	27260156	MEWO	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.05824778327451141	[1213]	[1058,1311,893]	-1	hSpCas9	negative selection	7532979
44907878	44907901	19	-	27260156	MEWO	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.34459899657869575	[641]	[510,532,381]	-6	hSpCas9	negative selection	7532980
44906617	44906640	19	+	27260156	MEWO	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.4505541080457718	[81]	[106,85,121]	8	hSpCas9	negative selection	7532981
44909234	44909257	19	-	27260156	LNCAPCLONEFGC	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.27673245202073626	[798]	[858,940,911,795]	4	hSpCas9	negative selection	7589946
44908692	44908715	19	+	27260156	LNCAPCLONEFGC	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.0441921619610461	[30]	[29,94,59,44]	9	hSpCas9	negative selection	7589947
44907815	44907838	19	-	27260156	LNCAPCLONEFGC	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.8527753327543891	[411]	[492,618,823,788]	9	hSpCas9	negative selection	7589948
44906642	44906665	19	+	27260156	LNCAPCLONEFGC	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.07598331024799165	[1213]	[901,853,1361,1116]	-1	hSpCas9	negative selection	7654230
44907878	44907901	19	-	27260156	LNCAPCLONEFGC	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.017680859700849094	[641]	[520,420,562,801]	0	hSpCas9	negative selection	7654231
44906617	44906640	19	+	27260156	LNCAPCLONEFGC	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.5923943612360525	[81]	[94,74,194,97]	8	hSpCas9	negative selection	7654232
44909234	44909257	19	-	27260156	PANC0327	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.08919392033495	[798]	[685,541,964,848]	1	hSpCas9	negative selection	7711197
44908692	44908715	19	+	27260156	PANC0327	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.22127915775617524	[30]	[12,45,15,49]	3	hSpCas9	negative selection	7711198
44907815	44907838	19	-	27260156	PANC0327	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	1.018408918902937	[411]	[1235,486,848,466]	9	hSpCas9	negative selection	7711199
44906642	44906665	19	+	27260156	PANC0327	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.1930657044658124	[1213]	[1061,708,979,1061]	-3	hSpCas9	negative selection	7775481
44907878	44907901	19	-	27260156	PANC0327	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.43753450046957476	[641]	[449,408,326,501]	-6	hSpCas9	negative selection	7775482
44906617	44906640	19	+	27260156	PANC0327	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.3124735631571345	[81]	[17,227,21,69]	4	hSpCas9	negative selection	7775483
44909234	44909257	19	-	27260156	NCIH2009	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.5807881671930387	[798]	[2146,1640,1312]	7	hSpCas9	negative selection	7832448
44908692	44908715	19	+	27260156	NCIH2009	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.9227694918930527	[30]	[90,78,77]	9	hSpCas9	negative selection	7832449
44907815	44907838	19	-	27260156	NCIH2009	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.7878177203350242	[411]	[888,1158,907]	9	hSpCas9	negative selection	7832450
44906642	44906665	19	+	27260156	NCIH2009	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.09848219081303755	[1213]	[2360,1571,1623]	1	hSpCas9	negative selection	7896732
44907878	44907901	19	-	27260156	NCIH2009	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.5411167406735802	[641]	[585,684,569]	-6	hSpCas9	negative selection	7896733
44906617	44906640	19	+	27260156	NCIH2009	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.6530600033461147	[81]	[174,132,231]	8	hSpCas9	negative selection	7896734
44909234	44909257	19	-	27260156	NCIH1373	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.7606355719436123	[798]	[1291,1565,1672,389]	7	hSpCas9	negative selection	7953699
44908692	44908715	19	+	27260156	NCIH1373	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.1473686154428542	[30]	[286,27,12,3]	9	hSpCas9	negative selection	7953700
44907815	44907838	19	-	27260156	NCIH1373	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	1.0745728049503804	[411]	[1116,1171,902,177]	9	hSpCas9	negative selection	7953701
44906642	44906665	19	+	27260156	NCIH1373	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.2750156681518867	[1213]	[2052,1572,2090,229]	2	hSpCas9	negative selection	8017983
44907878	44907901	19	-	27260156	NCIH1373	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.005519205554854634	[641]	[1018,548,947,101]	0	hSpCas9	negative selection	8017984
44906617	44906640	19	+	27260156	NCIH1373	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.198422523078579	[81]	[176,90,7,42]	2	hSpCas9	negative selection	8017985
44909234	44909257	19	-	27260156	PATU8902	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.6826922330299577	[798]	[1573,2281,1005,2568]	7	hSpCas9	negative selection	8074950
44908692	44908715	19	+	27260156	PATU8902	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.07243115566341007	[30]	[5,4,122,24]	0	hSpCas9	negative selection	8074951
44907815	44907838	19	-	27260156	PATU8902	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	1.1475861967551246	[411]	[746,1629,1221,1526]	9	hSpCas9	negative selection	8074952
44906642	44906665	19	+	27260156	PATU8902	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.08188439601049002	[1213]	[1930,1679,919,2074]	-1	hSpCas9	negative selection	8139234
44907878	44907901	19	-	27260156	PATU8902	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.5435355066437151	[641]	[971,546,285,738]	-5	hSpCas9	negative selection	8139235
44906617	44906640	19	+	27260156	PATU8902	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.6162546661272574	[81]	[153,350,57,165]	6	hSpCas9	negative selection	8139236
44909234	44909257	19	-	27260156	PANC1	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.2361503048621315	[798]	[940,841,966,522]	4	hSpCas9	negative selection	8196201
44908692	44908715	19	+	27260156	PANC1	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.2958965698805187	[30]	[14,2,28,70]	5	hSpCas9	negative selection	8196202
44907815	44907838	19	-	27260156	PANC1	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.4500465357562701	[411]	[636,568,520,251]	7	hSpCas9	negative selection	8196203
44906642	44906665	19	+	27260156	PANC1	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.2689590207738306	[1213]	[1115,1628,1367,1012]	4	hSpCas9	negative selection	8260485
44907878	44907901	19	-	27260156	PANC1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.1339505854330018	[641]	[571,1039,620,315]	2	hSpCas9	negative selection	8260486
44906617	44906640	19	+	27260156	PANC1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	1.0947674871761264	[81]	[182,217,62,147]	9	hSpCas9	negative selection	8260487
44909234	44909257	19	-	27260156	PANC0813	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.24698241666670684	[798]	[1359,971,965,1173]	4	hSpCas9	negative selection	8317452
44908692	44908715	19	+	27260156	PANC0813	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.5614129495578952	[30]	[24,31,22,18]	-7	hSpCas9	negative selection	8317453
44907815	44907838	19	-	27260156	PANC0813	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.908283365990669	[411]	[861,704,1038,1015]	9	hSpCas9	negative selection	8317454
44906642	44906665	19	+	27260156	PANC0813	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.15469457893444183	[1213]	[1831,2058,1299,1198]	2	hSpCas9	negative selection	8381736
44907878	44907901	19	-	27260156	PANC0813	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.5568522661648267	[641]	[568,439,480,561]	-7	hSpCas9	negative selection	8381737
44906617	44906640	19	+	27260156	PANC0813	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.414291129105147	[81]	[71,117,29,278]	6	hSpCas9	negative selection	8381738
44909234	44909257	19	-	27260156	RDES	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.34406782730871177	[798]	[908,1051,1297,1493]	5	hSpCas9	negative selection	8438703
44908692	44908715	19	+	27260156	RDES	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.1425441102816456	[30]	[37,55,19,39]	2	hSpCas9	negative selection	8438704
44907815	44907838	19	-	27260156	RDES	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5885362153407255	[411]	[550,767,831,710]	8	hSpCas9	negative selection	8438705
44906642	44906665	19	+	27260156	RDES	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.08475054776702962	[1213]	[1226,1342,1694,1725]	1	hSpCas9	negative selection	8502987
44907878	44907901	19	-	27260156	RDES	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.06305893525730649	[641]	[537,735,603,1002]	-1	hSpCas9	negative selection	8502988
44906617	44906640	19	+	27260156	RDES	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.6183893337602542	[81]	[44,41,80,85]	-8	hSpCas9	negative selection	8502989
44909234	44909257	19	-	27260156	PC3	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.14429627199060424	[798]	[475,944,1349,1036]	3	hSpCas9	negative selection	8559954
44908692	44908715	19	+	27260156	PC3	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	-0.2676020408380433	[30]	[5,23,23,56]	-6	hSpCas9	negative selection	8559955
44907815	44907838	19	-	27260156	PC3	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	-0.034503068817363064	[411]	[258,314,797,414]	-1	hSpCas9	negative selection	8559956
44906642	44906665	19	+	27260156	PC3	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.15228495293086008	[1213]	[897,1142,2446,1392]	3	hSpCas9	negative selection	8624238
44907878	44907901	19	-	27260156	PC3	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.3174426526730433	[641]	[333,591,736,498]	-6	hSpCas9	negative selection	8624239
44906617	44906640	19	+	27260156	PC3	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.28422696210150544	[81]	[64,24,88,92]	-6	hSpCas9	negative selection	8624240
44909234	44909257	19	-	27260156	PATU8988T	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.4409170583184715	[798]	[883,1074,1025,1223]	7	hSpCas9	negative selection	8681205
44908692	44908715	19	+	27260156	PATU8988T	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.8123669131482978	[30]	[94,25,45,39]	9	hSpCas9	negative selection	8681206
44907815	44907838	19	-	27260156	PATU8988T	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.6871269313578877	[411]	[686,882,497,509]	9	hSpCas9	negative selection	8681207
44906642	44906665	19	+	27260156	PATU8988T	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.34445907152250044	[1213]	[854,984,1103,739]	-5	hSpCas9	negative selection	8745489
44907878	44907901	19	-	27260156	PATU8988T	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.24595367013969377	[641]	[428,509,536,622]	-4	hSpCas9	negative selection	8745490
44906617	44906640	19	+	27260156	PATU8988T	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.865609010913772	[81]	[323,58,110,69]	9	hSpCas9	negative selection	8745491
44909234	44909257	19	-	27260156	T47D	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.1041940649254891	[798]	[946,966,968,1125]	2	hSpCas9	negative selection	8802456
44908692	44908715	19	+	27260156	T47D	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.4656503388501232	[30]	[58,50,30,58]	8	hSpCas9	negative selection	8802457
44907815	44907838	19	-	27260156	T47D	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.5625343330862238	[411]	[804,528,861,650]	9	hSpCas9	negative selection	8802458
44906642	44906665	19	+	27260156	T47D	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.2213495637413454	[1213]	[1147,1202,1155,1350]	-5	hSpCas9	negative selection	8866740
44907878	44907901	19	-	27260156	T47D	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.4593023694751652	[641]	[624,439,548,571]	-7	hSpCas9	negative selection	8866741
44906617	44906640	19	+	27260156	T47D	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.08228055334771289	[81]	[150,69,78,107]	1	hSpCas9	negative selection	8866742
44909234	44909257	19	-	27260156	SU8686	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.2899693816838719	[798]	[792,890,1213,1012]	5	hSpCas9	negative selection	8923707
44908692	44908715	19	+	27260156	SU8686	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5059064297468394	[30]	[23,33,43,81]	8	hSpCas9	negative selection	8923708
44907815	44907838	19	-	27260156	SU8686	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.6019846124967017	[411]	[606,501,662,740]	8	hSpCas9	negative selection	8923709
44906642	44906665	19	+	27260156	SU8686	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	0.07342877552293459	[1213]	[1096,969,1385,1741]	1	hSpCas9	negative selection	8987991
44907878	44907901	19	-	27260156	SU8686	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.17747865060729773	[641]	[566,472,433,822]	-3	hSpCas9	negative selection	8987992
44906617	44906640	19	+	27260156	SU8686	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.3531594920331549	[81]	[41,85,71,51]	-5	hSpCas9	negative selection	8987993
44909234	44909257	19	-	27260156	SKES1	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.24244555274462887	[798]	[1246,1042,987,580]	5	hSpCas9	negative selection	9044958
44908692	44908715	19	+	27260156	SKES1	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5189150322200398	[30]	[74,50,29,27]	9	hSpCas9	negative selection	9044959
44907815	44907838	19	-	27260156	SKES1	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.4843226271784109	[411]	[706,653,481,489]	8	hSpCas9	negative selection	9044960
44906642	44906665	19	+	27260156	SKES1	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.18821106726169612	[1213]	[1253,1147,1040,858]	-4	hSpCas9	negative selection	9109242
44907878	44907901	19	-	27260156	SKES1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.3697586637200423	[641]	[537,579,424,455]	-7	hSpCas9	negative selection	9109243
44906617	44906640	19	+	27260156	SKES1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.1302306341747519	[81]	[60,164,48,87]	3	hSpCas9	negative selection	9109244
44909234	44909257	19	-	27260156	TOV112D	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.282670652797231	[798]	[887,1010,1158,839]	5	hSpCas9	negative selection	9166209
44908692	44908715	19	+	27260156	TOV112D	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.5453383914098366	[30]	[102,27,13,36]	8	hSpCas9	negative selection	9166210
44907815	44907838	19	-	27260156	TOV112D	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.4400133339556065	[411]	[643,563,428,607]	7	hSpCas9	negative selection	9166211
44906642	44906665	19	+	27260156	TOV112D	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.1490247809561105	[1213]	[1137,1280,979,1035]	-3	hSpCas9	negative selection	9230493
44907878	44907901	19	-	27260156	TOV112D	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.1806750047444064	[641]	[602,474,690,481]	-4	hSpCas9	negative selection	9230494
44906617	44906640	19	+	27260156	TOV112D	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.11571065979011319	[81]	[53,98,101,99]	2	hSpCas9	negative selection	9230495
44909234	44909257	19	-	27260156	TC71	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	-0.05803465896100757	[798]	[732,812,975,761]	-1	hSpCas9	negative selection	9287460
44908692	44908715	19	+	27260156	TC71	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	0.14685764706299453	[30]	[48,9,44,42]	3	hSpCas9	negative selection	9287461
44907815	44907838	19	-	27260156	TC71	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.2704844146657242	[411]	[531,480,564,552]	6	hSpCas9	negative selection	9287462
44906642	44906665	19	+	27260156	TC71	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.10551888966986533	[1213]	[1183,1150,1171,1340]	-3	hSpCas9	negative selection	9351744
44907878	44907901	19	-	27260156	TC71	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.12790661243411594	[641]	[624,625,617,651]	-3	hSpCas9	negative selection	9351745
44906617	44906640	19	+	27260156	TC71	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.29924256275241135	[81]	[90,82,155,100]	7	hSpCas9	negative selection	9351746
44909234	44909257	19	-	27260156	TC32	viability	CGGCGTTCAGTGATTGTCGCTGG	APOE	ENSG00000130203	0.3580835329047921	[798]	[975,637,1126,1215]	6	hSpCas9	negative selection	9408711
44908692	44908715	19	+	27260156	TC32	viability	CCTGGTGCAGTACCGCGGCGAGG	APOE	ENSG00000130203	1.565916375787459	[30]	[68,91,72,103]	9	hSpCas9	negative selection	9408712
44907815	44907838	19	-	27260156	TC32	viability	CGCTCTGCCACTCGGTCTGCTGG	APOE	ENSG00000130203	0.7628026260988044	[411]	[555,471,821,862]	9	hSpCas9	negative selection	9408713
44906642	44906665	19	+	27260156	TC32	viability	TGCGTTGCTGGTCACATTCCTGG	APOE	ENSG00000130203	-0.13593020396605104	[1213]	[963,863,1352,1037]	-2	hSpCas9	negative selection	9472995
44907878	44907901	19	-	27260156	TC32	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.20029528893009083	[641]	[519,326,734,604]	-4	hSpCas9	negative selection	9472996
44906617	44906640	19	+	27260156	TC32	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.3276719666283787	[81]	[63,32,56,99]	-6	hSpCas9	negative selection	9472997
44907839	44907862	19	+	27869803	HPAFII	viability after 27 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.4329494234692026	[222]	[244,85,NaN]	3	hSpCas9	negative selection	9568399
44907839	44907862	19	-	27869803	HPAFII	viability after 27 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.273144537668983	[778]	[295,63,NaN]	-7	hSpCas9	negative selection	9568400
44908897	44908920	19	-	27869803	HPAFII	viability after 27 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.047012472052978094	[700]	[395,323,NaN]	0	hSpCas9	negative selection	9568401
44909126	44909149	19	-	27869803	HPAFII	viability after 27 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.7650926764833457	[331]	[180,392,NaN]	6	hSpCas9	negative selection	9568402
44909150	44909173	19	-	27869803	HPAFII	viability after 27 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.5064658458416802	[844]	[321,304,NaN]	-4	hSpCas9	negative selection	9568403
44909162	44909185	19	+	27869803	HPAFII	viability after 27 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.12283745261051983	[269]	[167,98,NaN]	-1	hSpCas9	negative selection	9568404
44907839	44907862	19	+	27869803	HPAFII	viability after 15 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.1549814061553135	[222]	[383,193,NaN]	1	hSpCas9	negative selection	9650848
44907839	44907862	19	-	27869803	HPAFII	viability after 15 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.077325630158199	[778]	[516,321,NaN]	-8	hSpCas9	negative selection	9650849
44908897	44908920	19	-	27869803	HPAFII	viability after 15 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.3065199900776061	[700]	[1223,749,NaN]	3	hSpCas9	negative selection	9650850
44909126	44909149	19	-	27869803	HPAFII	viability after 15 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.15910874544917702	[331]	[538,310,NaN]	1	hSpCas9	negative selection	9650851
44909150	44909173	19	-	27869803	HPAFII	viability after 15 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.3462377877345386	[844]	[833,639,NaN]	-4	hSpCas9	negative selection	9650852
44909162	44909185	19	+	27869803	HPAFII	viability after 15 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.057665498647884186	[269]	[412,232,NaN]	0	hSpCas9	negative selection	9650853
44907839	44907862	19	+	27869803	ASPC1	viability after 36 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.25673414753478796	[546]	[525,150,77]	2	hSpCas9	negative selection	9733297
44907839	44907862	19	-	27869803	ASPC1	viability after 36 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.05495023728896831	[2101]	[1014,746,588]	0	hSpCas9	negative selection	9733298
44908897	44908920	19	-	27869803	ASPC1	viability after 36 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	1.7057788891656733	[1465]	[1124,640,2849]	9	hSpCas9	negative selection	9733299
44909126	44909149	19	-	27869803	ASPC1	viability after 36 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.40102957750736834	[1139]	[297,160,411]	-4	hSpCas9	negative selection	9733300
44909150	44909173	19	-	27869803	ASPC1	viability after 36 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.2057723234962079	[1860]	[458,835,413]	-2	hSpCas9	negative selection	9733301
44909162	44909185	19	+	27869803	ASPC1	viability after 36 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	-0.6310159915260081	[667]	[182,102,163]	-6	hSpCas9	negative selection	9733302
44907839	44907862	19	+	27869803	PATU8988S	viability after 35 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.22467883226536253	[523]	[226,133,NaN]	-2	hSpCas9	negative selection	9815746
44907839	44907862	19	-	27869803	PATU8988S	viability after 35 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.23254075773483418	[2242]	[938,597,NaN]	-2	hSpCas9	negative selection	9815747
44908897	44908920	19	-	27869803	PATU8988S	viability after 35 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	0.1902018429571335	[1392]	[680,598,NaN]	2	hSpCas9	negative selection	9815748
44909126	44909149	19	-	27869803	PATU8988S	viability after 35 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.02168868523993772	[856]	[342,336,NaN]	0	hSpCas9	negative selection	9815749
44909150	44909173	19	-	27869803	PATU8988S	viability after 35 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.029047164053002783	[1751]	[714,667,NaN]	0	hSpCas9	negative selection	9815750
44909162	44909185	19	+	27869803	PATU8988S	viability after 35 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.07177232593077842	[395]	[221,112,NaN]	0	hSpCas9	negative selection	9815751
44907839	44907862	19	+	27869803	PATU8988S	viability after 31 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	-0.10439790691451098	[523]	[174,218,NaN]	-1	hSpCas9	negative selection	9898195
44907839	44907862	19	-	27869803	PATU8988S	viability after 31 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.22545643445952912	[2242]	[698,848,NaN]	-3	hSpCas9	negative selection	9898196
44908897	44908920	19	-	27869803	PATU8988S	viability after 31 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.27537584170962504	[1392]	[516,384,NaN]	-3	hSpCas9	negative selection	9898197
44909126	44909149	19	-	27869803	PATU8988S	viability after 31 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	-0.20799363255804493	[856]	[312,273,NaN]	-2	hSpCas9	negative selection	9898198
44909150	44909173	19	-	27869803	PATU8988S	viability after 31 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.24371545563477293	[1751]	[461,752,NaN]	-3	hSpCas9	negative selection	9898199
44909162	44909185	19	+	27869803	PATU8988S	viability after 31 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.40978183449119165	[395]	[262,141,NaN]	5	hSpCas9	negative selection	9898200
44907839	44907862	19	+	27869803	HPAFII	viability after 35 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.27254563646384283	[222]	[165,102,NaN]	1	hSpCas9	negative selection	9980644
44907839	44907862	19	-	27869803	HPAFII	viability after 35 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.1648992446083741	[778]	[181,168,NaN]	-6	hSpCas9	negative selection	9980645
44908897	44908920	19	-	27869803	HPAFII	viability after 35 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.3453449527677197	[700]	[236,326,NaN]	-2	hSpCas9	negative selection	9980646
44909126	44909149	19	-	27869803	HPAFII	viability after 35 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.8280916944943455	[331]	[248,353,NaN]	5	hSpCas9	negative selection	9980647
44909150	44909173	19	-	27869803	HPAFII	viability after 35 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.4754513954570043	[844]	[246,375,NaN]	-3	hSpCas9	negative selection	9980648
44909162	44909185	19	+	27869803	HPAFII	viability after 35 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.19585646204351626	[269]	[220,83,NaN]	1	hSpCas9	negative selection	9980649
44907839	44907862	19	+	27869803	HPAFII	viability after 31 days	CCAGCGCTGGGAACTGGCACTGG	APOE	ENSG00000130203	0.0794393627772328	[222]	[170,89,NaN]	0	hSpCas9	negative selection	10063093
44907839	44907862	19	-	27869803	HPAFII	viability after 31 days	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-1.3734256941974237	[778]	[229,101,NaN]	-7	hSpCas9	negative selection	10063094
44908897	44908920	19	-	27869803	HPAFII	viability after 31 days	ACGCGGCCCTGTTCCACCAGGGG	APOE	ENSG00000130203	-0.2617192150150458	[700]	[308,348,NaN]	-2	hSpCas9	negative selection	10063095
44909126	44909149	19	-	27869803	HPAFII	viability after 31 days	CTCGAACCAGCTCTTGAGGCGGG	APOE	ENSG00000130203	0.6513642367711532	[331]	[228,361,NaN]	5	hSpCas9	negative selection	10063096
44909150	44909173	19	-	27869803	HPAFII	viability after 31 days	GCGCTGCATGTCTTCCACCAGGG	APOE	ENSG00000130203	-0.49859179811440435	[844]	[260,416,NaN]	-3	hSpCas9	negative selection	10063097
44909162	44909185	19	+	27869803	HPAFII	viability after 31 days	ACATGCAGCGCCAGTGGGCCGGG	APOE	ENSG00000130203	0.11950133493168182	[269]	[222,100,NaN]	0	hSpCas9	negative selection	10063098
44907767	44907790	19	+	28162770	P31FUJ	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.24088455071223736	[178]	[177]	-2	hSpCas9	negative selection	10112239
44907826	44907849	19	+	28162770	P31FUJ	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10112240
44907878	44907901	19	-	28162770	P31FUJ	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.4655420957245202	[105]	[171]	5	hSpCas9	negative selection	10112241
44907893	44907916	19	+	28162770	P31FUJ	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.778770573519671	[145]	[99]	-6	hSpCas9	negative selection	10112242
44907865	44907888	19	+	28162770	P31FUJ	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.06952133253347242	[162]	[200]	0	hSpCas9	negative selection	10112243
44907752	44907775	19	+	28162770	P31FUJ	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.7901184107275381	[280]	[570]	8	hSpCas9	negative selection	10112244
44907839	44907862	19	-	28162770	P31FUJ	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.051418087597002296	[208]	[236]	0	hSpCas9	negative selection	10112245
44906617	44906640	19	+	28162770	P31FUJ	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.3883804842195309	[235]	[362]	4	hSpCas9	negative selection	10112246
44907779	44907802	19	+	28162770	P31FUJ	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-1.1726812119768077	[187]	[97]	-7	hSpCas9	negative selection	10112247
44907931	44907954	19	+	28162770	P31FUJ	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.10348118345005386	[399]	[504]	1	hSpCas9	negative selection	10112248
44907767	44907790	19	+	28162770	TF1	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10281605
44907826	44907849	19	+	28162770	TF1	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10281606
44907878	44907901	19	-	28162770	TF1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10281607
44907893	44907916	19	+	28162770	TF1	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10281608
44907865	44907888	19	+	28162770	TF1	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10281609
44907752	44907775	19	+	28162770	TF1	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	NaN	[NaN]	[310]	1	hSpCas9	negative selection	10281610
44907839	44907862	19	-	28162770	TF1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10281611
44906617	44906640	19	+	28162770	TF1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10281612
44907779	44907802	19	+	28162770	TF1	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10281613
44907931	44907954	19	+	28162770	TF1	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	NaN	[NaN]	[798]	1	hSpCas9	negative selection	10281614
44907767	44907790	19	+	28162770	SKM1	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.5545213871570196	[53]	[64]	-4	hSpCas9	negative selection	10450971
44907826	44907849	19	+	28162770	SKM1	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10450972
44907878	44907901	19	-	28162770	SKM1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.991229790372268	[34]	[122]	8	hSpCas9	negative selection	10450973
44907893	44907916	19	+	28162770	SKM1	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.5088438127623752	[32]	[40]	-4	hSpCas9	negative selection	10450974
44907865	44907888	19	+	28162770	SKM1	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.7065244806020693	[47]	[51]	-5	hSpCas9	negative selection	10450975
44907752	44907775	19	+	28162770	SKM1	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.27560909860441685	[99]	[213]	2	hSpCas9	negative selection	10450976
44907839	44907862	19	-	28162770	SKM1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.12553088208385882	[55]	[107]	1	hSpCas9	negative selection	10450977
44906617	44906640	19	+	28162770	SKM1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.29930459820012817	[56]	[123]	3	hSpCas9	negative selection	10450978
44907779	44907802	19	+	28162770	SKM1	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.5000736031346431	[31]	[39]	-4	hSpCas9	negative selection	10450979
44907931	44907954	19	+	28162770	SKM1	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.3275118433973465	[86]	[192]	3	hSpCas9	negative selection	10450980
44907767	44907790	19	+	28162770	SKM1	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.5545213871570196	[53]	[64]	-4	hSpCas9	negative selection	10620337
44907826	44907849	19	+	28162770	SKM1	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10620338
44907878	44907901	19	-	28162770	SKM1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.991229790372268	[34]	[122]	8	hSpCas9	negative selection	10620339
44907893	44907916	19	+	28162770	SKM1	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.5088438127623752	[32]	[40]	-4	hSpCas9	negative selection	10620340
44907865	44907888	19	+	28162770	SKM1	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.7065244806020693	[47]	[51]	-5	hSpCas9	negative selection	10620341
44907752	44907775	19	+	28162770	SKM1	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.27560909860441685	[99]	[213]	2	hSpCas9	negative selection	10620342
44907839	44907862	19	-	28162770	SKM1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.12553088208385882	[55]	[107]	1	hSpCas9	negative selection	10620343
44906617	44906640	19	+	28162770	SKM1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.29930459820012817	[56]	[123]	3	hSpCas9	negative selection	10620344
44907779	44907802	19	+	28162770	SKM1	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.5000736031346431	[31]	[39]	-4	hSpCas9	negative selection	10620345
44907931	44907954	19	+	28162770	SKM1	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.3275118433973465	[86]	[192]	3	hSpCas9	negative selection	10620346
44907767	44907790	19	+	28162770	PL21	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.06462464383283906	[144]	[65]	0	hSpCas9	negative selection	10789703
44907826	44907849	19	+	28162770	PL21	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10789704
44907878	44907901	19	-	28162770	PL21	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.1281862515961928	[112]	[44]	-1	hSpCas9	negative selection	10789705
44907893	44907916	19	+	28162770	PL21	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	1.0569449786615295	[126]	[114]	8	hSpCas9	negative selection	10789706
44907865	44907888	19	+	28162770	PL21	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.044020412572038314	[155]	[69]	0	hSpCas9	negative selection	10789707
44907752	44907775	19	+	28162770	PL21	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.9757476155065236	[360]	[308]	7	hSpCas9	negative selection	10789708
44907839	44907862	19	-	28162770	PL21	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.4123036226539431	[158]	[51]	-3	hSpCas9	negative selection	10789709
44906617	44906640	19	+	28162770	PL21	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.1930935144711753	[196]	[74]	-1	hSpCas9	negative selection	10789710
44907779	44907802	19	+	28162770	PL21	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-1.8408876537707344	[106]	[12]	-8	hSpCas9	negative selection	10789711
44907931	44907954	19	+	28162770	PL21	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.6795363595645422	[273]	[190]	6	hSpCas9	negative selection	10789712
44907767	44907790	19	+	28162770	P31FUJ	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.24088455071223736	[178]	[177]	-2	hSpCas9	negative selection	10959069
44907826	44907849	19	+	28162770	P31FUJ	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10959070
44907878	44907901	19	-	28162770	P31FUJ	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.4655420957245202	[105]	[171]	5	hSpCas9	negative selection	10959071
44907893	44907916	19	+	28162770	P31FUJ	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.778770573519671	[145]	[99]	-6	hSpCas9	negative selection	10959072
44907865	44907888	19	+	28162770	P31FUJ	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.06952133253347242	[162]	[200]	0	hSpCas9	negative selection	10959073
44907752	44907775	19	+	28162770	P31FUJ	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.7901184107275381	[280]	[570]	8	hSpCas9	negative selection	10959074
44907839	44907862	19	-	28162770	P31FUJ	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.051418087597002296	[208]	[236]	0	hSpCas9	negative selection	10959075
44906617	44906640	19	+	28162770	P31FUJ	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.3883804842195309	[235]	[362]	4	hSpCas9	negative selection	10959076
44907779	44907802	19	+	28162770	P31FUJ	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-1.1726812119768077	[187]	[97]	-7	hSpCas9	negative selection	10959077
44907931	44907954	19	+	28162770	P31FUJ	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.10348118345005386	[399]	[504]	1	hSpCas9	negative selection	10959078
44907767	44907790	19	+	28162770	OCIAML5	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.11917064100683761	[70]	[117]	-1	hSpCas9	negative selection	11128435
44907826	44907849	19	+	28162770	OCIAML5	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11128436
44907878	44907901	19	-	28162770	OCIAML5	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.491664328161999	[73]	[94]	-3	hSpCas9	negative selection	11128437
44907893	44907916	19	+	28162770	OCIAML5	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.029525244991716937	[107]	[190]	0	hSpCas9	negative selection	11128438
44907865	44907888	19	+	28162770	OCIAML5	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.060950127541363086	[93]	[176]	0	hSpCas9	negative selection	11128439
44907752	44907775	19	+	28162770	OCIAML5	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.24590858869930043	[184]	[395]	2	hSpCas9	negative selection	11128440
44907839	44907862	19	-	28162770	OCIAML5	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.554161705183151	[108]	[133]	-4	hSpCas9	negative selection	11128441
44906617	44906640	19	+	28162770	OCIAML5	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.11668249515156326	[139]	[273]	1	hSpCas9	negative selection	11128442
44907779	44907802	19	+	28162770	OCIAML5	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.919180766722534	[87]	[83]	-5	hSpCas9	negative selection	11128443
44907931	44907954	19	+	28162770	OCIAML5	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.5440624658647821	[143]	[378]	5	hSpCas9	negative selection	11128444
44907767	44907790	19	+	28162770	EOL1	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.46836691681016923	[301]	[114]	-3	hSpCas9	negative selection	11297801
44907826	44907849	19	+	28162770	EOL1	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11297802
44907878	44907901	19	-	28162770	EOL1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.07210495998439226	[194]	[107]	0	hSpCas9	negative selection	11297803
44907893	44907916	19	+	28162770	EOL1	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	1.5237642559719324	[234]	[355]	9	hSpCas9	negative selection	11297804
44907865	44907888	19	+	28162770	EOL1	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.43054718725202723	[219]	[85]	-3	hSpCas9	negative selection	11297805
44907752	44907775	19	+	28162770	EOL1	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.7174653104043316	[702]	[608]	6	hSpCas9	negative selection	11297806
44907839	44907862	19	-	28162770	EOL1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.20603633823960976	[207]	[94]	-1	hSpCas9	negative selection	11297807
44906617	44906640	19	+	28162770	EOL1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.08094821618431744	[262]	[130]	0	hSpCas9	negative selection	11297808
44907779	44907802	19	+	28162770	EOL1	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.4653987467454792	[75]	[28]	-3	hSpCas9	negative selection	11297809
44907931	44907954	19	+	28162770	EOL1	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	-0.2377236573283425	[375]	[167]	-2	hSpCas9	negative selection	11297810
44907767	44907790	19	+	28162770	MOLM13	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.47428715274272953	[224]	[225]	3	hSpCas9	negative selection	11467167
44907826	44907849	19	+	28162770	MOLM13	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11467168
44907878	44907901	19	-	28162770	MOLM13	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	-0.3476860473179937	[175]	[99]	-2	hSpCas9	negative selection	11467169
44907893	44907916	19	+	28162770	MOLM13	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	1.2348300351562749	[180]	[307]	8	hSpCas9	negative selection	11467170
44907865	44907888	19	+	28162770	MOLM13	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.09783933703904504	[220]	[170]	0	hSpCas9	negative selection	11467171
44907752	44907775	19	+	28162770	MOLM13	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.42676464815837545	[426]	[414]	3	hSpCas9	negative selection	11467172
44907839	44907862	19	-	28162770	MOLM13	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.647373211411736	[233]	[264]	5	hSpCas9	negative selection	11467173
44906617	44906640	19	+	28162770	MOLM13	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.4614343594072794	[223]	[222]	3	hSpCas9	negative selection	11467174
44907779	44907802	19	+	28162770	MOLM13	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-1.0453716538223887	[156]	[54]	-5	hSpCas9	negative selection	11467175
44907931	44907954	19	+	28162770	MOLM13	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.7274348012984927	[344]	[412]	5	hSpCas9	negative selection	11467176
44907767	44907790	19	+	28162770	HEL	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.03799371908866331	[256]	[168]	0	hSpCas9	negative selection	11636533
44907826	44907849	19	+	28162770	HEL	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.6427388320003571	[0]	[0]	5	hSpCas9	negative selection	11636534
44907878	44907901	19	-	28162770	HEL	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	1.1659251351348232	[166]	[239]	8	hSpCas9	negative selection	11636535
44907893	44907916	19	+	28162770	HEL	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.3133178204120461	[193]	[99]	-2	hSpCas9	negative selection	11636536
44907865	44907888	19	+	28162770	HEL	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.5559775200810735	[256]	[241]	5	hSpCas9	negative selection	11636537
44907752	44907775	19	+	28162770	HEL	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	1.0889062287233715	[446]	[608]	8	hSpCas9	negative selection	11636538
44907839	44907862	19	-	28162770	HEL	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.7523633231748552	[151]	[163]	6	hSpCas9	negative selection	11636539
44906617	44906640	19	+	28162770	HEL	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.6160214936245775	[217]	[213]	5	hSpCas9	negative selection	11636540
44907779	44907802	19	+	28162770	HEL	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.785354820103933	[147]	[54]	-5	hSpCas9	negative selection	11636541
44907931	44907954	19	+	28162770	HEL	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.12879579459921847	[326]	[228]	1	hSpCas9	negative selection	11636542
44907767	44907790	19	+	28162770	MV411	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.51220077053332	[138]	[166]	4	hSpCas9	negative selection	11805899
44907826	44907849	19	+	28162770	MV411	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11805900
44907878	44907901	19	-	28162770	MV411	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.29288052154394234	[124]	[128]	2	hSpCas9	negative selection	11805901
44907893	44907916	19	+	28162770	MV411	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	1.7320330929741612	[123]	[346]	9	hSpCas9	negative selection	11805902
44907865	44907888	19	+	28162770	MV411	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.20463067944103563	[170]	[124]	-1	hSpCas9	negative selection	11805903
44907752	44907775	19	+	28162770	MV411	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.2935667215119765	[276]	[285]	2	hSpCas9	negative selection	11805904
44907839	44907862	19	-	28162770	MV411	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.8689259275290455	[116]	[179]	7	hSpCas9	negative selection	11805905
44906617	44906640	19	+	28162770	MV411	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	-0.22829588018362237	[177]	[127]	-2	hSpCas9	negative selection	11805906
44907779	44907802	19	+	28162770	MV411	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.32514122548254853	[57]	[38]	-2	hSpCas9	negative selection	11805907
44907931	44907954	19	+	28162770	MV411	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.4116669465610847	[281]	[315]	3	hSpCas9	negative selection	11805908
44907767	44907790	19	+	28162770	MONOMAC1	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	-0.9612239099607841	[106]	[62]	-6	hSpCas9	negative selection	11975265
44907826	44907849	19	+	28162770	MONOMAC1	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	11975266
44907878	44907901	19	-	28162770	MONOMAC1	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.05294140594879371	[73]	[87]	0	hSpCas9	negative selection	11975267
44907893	44907916	19	+	28162770	MONOMAC1	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	0.05535031457473172	[67]	[80]	0	hSpCas9	negative selection	11975268
44907865	44907888	19	+	28162770	MONOMAC1	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.24810268400870933	[82]	[112]	2	hSpCas9	negative selection	11975269
44907752	44907775	19	+	28162770	MONOMAC1	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.36422139307033385	[224]	[331]	3	hSpCas9	negative selection	11975270
44907839	44907862	19	-	28162770	MONOMAC1	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.2883899801106881	[99]	[139]	3	hSpCas9	negative selection	11975271
44906617	44906640	19	+	28162770	MONOMAC1	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.5517059148830061	[121]	[204]	5	hSpCas9	negative selection	11975272
44907779	44907802	19	+	28162770	MONOMAC1	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.659380061116754	[61]	[44]	-5	hSpCas9	negative selection	11975273
44907931	44907954	19	+	28162770	MONOMAC1	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.40160059055867897	[139]	[211]	4	hSpCas9	negative selection	11975274
44907767	44907790	19	+	28162770	OCIAML2	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	0.6536983097600404	[24]	[217]	6	hSpCas9	negative selection	12144631
44907826	44907849	19	+	28162770	OCIAML2	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12144632
44907878	44907901	19	-	28162770	OCIAML2	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	0.39610364389437447	[16]	[123]	4	hSpCas9	negative selection	12144633
44907893	44907916	19	+	28162770	OCIAML2	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.44893475414284223	[32]	[133]	-4	hSpCas9	negative selection	12144634
44907865	44907888	19	+	28162770	OCIAML2	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	-0.9221932005461191	[39]	[116]	-6	hSpCas9	negative selection	12144635
44907752	44907775	19	+	28162770	OCIAML2	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.20548056353719024	[68]	[440]	2	hSpCas9	negative selection	12144636
44907839	44907862	19	-	28162770	OCIAML2	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	0.40383929267397983	[20]	[153]	4	hSpCas9	negative selection	12144637
44906617	44906640	19	+	28162770	OCIAML2	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.2936563749235569	[33]	[230]	3	hSpCas9	negative selection	12144638
44907779	44907802	19	+	28162770	OCIAML2	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	-0.30070482379984875	[23]	[107]	-2	hSpCas9	negative selection	12144639
44907931	44907954	19	+	28162770	OCIAML2	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.3622601889225806	[39]	[284]	3	hSpCas9	negative selection	12144640
44907767	44907790	19	+	28162770	OCIAML3	viability	GGCCAAGGTGGAGCAAGCGGTGG	APOE	ENSG00000130203	1.4429434958487284	[52]	[434]	9	hSpCas9	negative selection	12313997
44907826	44907849	19	+	28162770	OCIAML3	viability	AGTGGCAGAGCGGCCAGCGCTGG	APOE	ENSG00000130203	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12313998
44907878	44907901	19	-	28162770	OCIAML3	viability	ACAGTGTCTGCACCCAGCGCAGG	APOE	ENSG00000130203	1.8080908032471825	[27]	[295]	9	hSpCas9	negative selection	12313999
44907893	44907916	19	+	28162770	OCIAML3	viability	GACACTGTCTGAGCAGGTGCAGG	APOE	ENSG00000130203	-0.5940076403241631	[35]	[71]	-4	hSpCas9	negative selection	12314000
44907865	44907888	19	+	28162770	OCIAML3	viability	GCTTTTGGGATTACCTGCGCTGG	APOE	ENSG00000130203	0.7969070647545067	[48]	[256]	7	hSpCas9	negative selection	12314001
44907752	44907775	19	+	28162770	OCIAML3	viability	CCACACAGGATGCCAGGCCAAGG	APOE	ENSG00000130203	0.5662283049497153	[82]	[370]	5	hSpCas9	negative selection	12314002
44907839	44907862	19	-	28162770	OCIAML3	viability	CCAGTGCCAGTTCCCAGCGCTGG	APOE	ENSG00000130203	-0.8646552302678321	[37]	[62]	-6	hSpCas9	negative selection	12314003
44906617	44906640	19	+	28162770	OCIAML3	viability	GCAGGAAGATGAAGGTTCTGTGG	APOE	ENSG00000130203	0.2761549220332554	[60]	[222]	2	hSpCas9	negative selection	12314004
44907779	44907802	19	+	28162770	OCIAML3	viability	GCAAGCGGTGGAGACAGAGCCGG	APOE	ENSG00000130203	0.9047982166472783	[22]	[129]	7	hSpCas9	negative selection	12314005
44907931	44907954	19	+	28162770	OCIAML3	viability	CCCAGGTCACCCAGGAACTGAGG	APOE	ENSG00000130203	0.3680245094768164	[76]	[299]	3	hSpCas9	negative selection	12314006