Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 353
• Symbol: APRT
• Description: adenine phosphoribosyltransferase

DataSource: http://genomecrispr.dkfz.de/#!/results/APRT

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88810118	88810141	16	-	26472758	Jiyoye	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-1.1288775187343365	[86]	[29]	-6	hSpCas9	negative selection	8670
88811572	88811595	16	-	26472758	Jiyoye	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.21731548340192	[36]	[5]	-8	hSpCas9	negative selection	8671
88811608	88811631	16	+	26472758	Jiyoye	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	3.4071753815058727	[0]	[7]	9	hSpCas9	negative selection	8672
88810438	88810461	16	+	26472758	Jiyoye	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.0185885243660289	[179]	[66]	-6	hSpCas9	negative selection	8673
88810069	88810092	16	-	26472758	Jiyoye	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.08681345916779243	[168]	[119]	0	hSpCas9	negative selection	8674
88810056	88810079	16	+	26472758	Jiyoye	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-1.128034084018183	[170]	[58]	-6	hSpCas9	negative selection	8675
88811623	88811646	16	+	26472758	Jiyoye	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-0.8465812107399098	[30]	[12]	-5	hSpCas9	negative selection	8676
88811590	88811613	16	+	26472758	Jiyoye	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	1.4977779302867802	[53]	[114]	8	hSpCas9	negative selection	8677
88810477	88810500	16	-	26472758	Jiyoye	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.019450092048182065	[124]	[92]	0	hSpCas9	negative selection	8678
88811839	88811862	16	+	26472758	Jiyoye	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.6021913639110161	[75]	[86]	4	hSpCas9	negative selection	8679
88810118	88810141	16	-	26472758	KBM7	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-1.47153313755787	[189,119]	[38,13]	-8	hSpCas9	negative selection	199788
88811572	88811595	16	-	26472758	KBM7	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.0132674105167057	[137,140]	[47,18]	-7	hSpCas9	negative selection	199789
88811608	88811631	16	+	26472758	KBM7	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-4.508342867873897	[126,148]	[4,0]	-9	hSpCas9	negative selection	199790
88810438	88810461	16	+	26472758	KBM7	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-0.6848514363253638	[393,257]	[163,30]	-5	hSpCas9	negative selection	199791
88810069	88810092	16	-	26472758	KBM7	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.6547152044141245	[603,340]	[188,91]	-5	hSpCas9	negative selection	199792
88810056	88810079	16	+	26472758	KBM7	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.01270048703749288	[550,232]	[156,192]	0	hSpCas9	negative selection	199793
88811623	88811646	16	+	26472758	KBM7	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.191921330892176	[211,159]	[29,44]	-7	hSpCas9	negative selection	199794
88811590	88811613	16	+	26472758	KBM7	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.27080771434785256	[583,482]	[259,337]	3	hSpCas9	negative selection	199795
88810477	88810500	16	-	26472758	KBM7	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.40637955392202685	[839,1159]	[318,400]	-4	hSpCas9	negative selection	199796
88811839	88811862	16	+	26472758	KBM7	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.6197644572055491	[347,268]	[147,44]	-5	hSpCas9	negative selection	199797
88810118	88810141	16	-	26472758	Raji	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	1.8558447683776351	[49]	[41]	9	hSpCas9	negative selection	390906
88811572	88811595	16	-	26472758	Raji	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.07095370588491301	[85]	[18]	0	hSpCas9	negative selection	390907
88811608	88811631	16	+	26472758	Raji	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-2.846812775013276	[30]	[0]	-9	hSpCas9	negative selection	390908
88810438	88810461	16	+	26472758	Raji	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	0.8399032245086137	[129]	[53]	7	hSpCas9	negative selection	390909
88810069	88810092	16	-	26472758	Raji	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.6053345125459294	[235]	[35]	-5	hSpCas9	negative selection	390910
88810056	88810079	16	+	26472758	Raji	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.12055892412133278	[217]	[54]	1	hSpCas9	negative selection	390911
88811623	88811646	16	+	26472758	Raji	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-2.082441023506418	[218]	[11]	-8	hSpCas9	negative selection	390912
88811590	88811613	16	+	26472758	Raji	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.1667620824525312	[356]	[92]	1	hSpCas9	negative selection	390913
88810477	88810500	16	-	26472758	Raji	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.029381023372326398	[569]	[134]	0	hSpCas9	negative selection	390914
88811839	88811862	16	+	26472758	Raji	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.20434526526068741	[186]	[49]	2	hSpCas9	negative selection	390915
88810118	88810141	16	-	26472758	K562	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.21691242388633203	[94]	[68]	-1	hSpCas9	negative selection	582024
88811572	88811595	16	-	26472758	K562	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.6918777046376681	[76]	[104]	5	hSpCas9	negative selection	582025
88811608	88811631	16	+	26472758	K562	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-3.033566019633318	[96]	[9]	-8	hSpCas9	negative selection	582026
88810438	88810461	16	+	26472758	K562	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-2.8406173761893525	[296]	[34]	-8	hSpCas9	negative selection	582027
88810069	88810092	16	-	26472758	K562	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.2560834199658935	[480]	[169]	-6	hSpCas9	negative selection	582028
88810056	88810079	16	+	26472758	K562	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.34655151270340045	[258]	[277]	2	hSpCas9	negative selection	582029
88811623	88811646	16	+	26472758	K562	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.82958185377733	[159]	[37]	-7	hSpCas9	negative selection	582030
88811590	88811613	16	+	26472758	K562	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.0878783406044607	[383]	[304]	0	hSpCas9	negative selection	582031
88810477	88810500	16	-	26472758	K562	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.04714447582247572	[857]	[700]	0	hSpCas9	negative selection	582032
88811839	88811862	16	+	26472758	K562	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-1.974894300738029	[311]	[66]	-7	hSpCas9	negative selection	582033
88809754	88809777	16	+	26627737	DLD1	viability	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.4722768668130224	[286]	[20,248,110]	5	hSpCas9	negative selection	795885
88810130	88810153	16	+	26627737	DLD1	viability	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.7411181146647141	[448]	[70,111,71]	-6	hSpCas9	negative selection	795886
88810476	88810499	16	-	26627737	DLD1	viability	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.4641073510993038	[1116]	[290,244,226]	-5	hSpCas9	negative selection	795887
88810541	88810564	16	-	26627737	DLD1	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5408332919437441	[1341]	[318,304,247]	-5	hSpCas9	negative selection	795888
88811572	88811595	16	-	26627737	DLD1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.1705162035478052	[156]	[15,52,0]	-8	hSpCas9	negative selection	795889
88811580	88811603	16	+	26627737	DLD1	viability	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.6291737255575469	[288]	[126,32,19]	-6	hSpCas9	negative selection	795890
88809754	88809777	16	+	26627737	GBM cells	viability after 5 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.0020073678497889436	[161]	[89,83]	0	hSpCas9	negative selection	878200
88810130	88810153	16	+	26627737	GBM cells	viability after 5 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.40338645774647386	[171]	[118,124]	6	hSpCas9	negative selection	878201
88810476	88810499	16	-	26627737	GBM cells	viability after 5 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.11258220339849934	[544]	[314,316]	1	hSpCas9	negative selection	878202
88810541	88810564	16	-	26627737	GBM cells	viability after 5 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5362078704364908	[867]	[370,270]	-7	hSpCas9	negative selection	878203
88811572	88811595	16	-	26627737	GBM cells	viability after 5 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.0020073678497891656	[53]	[32,24]	0	hSpCas9	negative selection	878204
88811580	88811603	16	+	26627737	GBM cells	viability after 5 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.49339914972534826	[150]	[113,113]	7	hSpCas9	negative selection	878205
88809754	88809777	16	+	26627737	GBM cells	viability after 13 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.6396656223517672	[161]	[158,118]	7	hSpCas9	negative selection	960515
88810130	88810153	16	+	26627737	GBM cells	viability after 13 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.4971754184713934	[171]	[123,137]	6	hSpCas9	negative selection	960516
88810476	88810499	16	-	26627737	GBM cells	viability after 13 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.10533881547138124	[544]	[318,238]	-1	hSpCas9	negative selection	960517
88810541	88810564	16	-	26627737	GBM cells	viability after 13 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6572924938333	[867]	[366,242]	-6	hSpCas9	negative selection	960518
88811572	88811595	16	-	26627737	GBM cells	viability after 13 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.5261402912254058	[53]	[21,18]	-6	hSpCas9	negative selection	960519
88811580	88811603	16	+	26627737	GBM cells	viability after 13 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.6914638505929255	[150]	[128,134]	8	hSpCas9	negative selection	960520
88809754	88809777	16	+	26627737	GBM cells	viability after 21 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.06063555020919531	[161]	[86,81]	0	hSpCas9	negative selection	1042830
88810130	88810153	16	+	26627737	GBM cells	viability after 21 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	1.1743838298198894	[171]	[224,197]	9	hSpCas9	negative selection	1042831
88810476	88810499	16	-	26627737	GBM cells	viability after 21 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.20868988786012177	[544]	[262,249]	-2	hSpCas9	negative selection	1042832
88810541	88810564	16	-	26627737	GBM cells	viability after 21 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.550201938705208	[867]	[320,322]	-5	hSpCas9	negative selection	1042833
88811572	88811595	16	-	26627737	GBM cells	viability after 21 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-3.289691701826654	[53]	[2,2]	-9	hSpCas9	negative selection	1042834
88811580	88811603	16	+	26627737	GBM cells	viability after 21 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.7305873589552271	[150]	[144,127]	7	hSpCas9	negative selection	1042835
88809754	88809777	16	+	26627737	RPE1	viability after 9 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.3689060483043025	[427]	[77,136]	-3	hSpCas9	negative selection	1125145
88810130	88810153	16	+	26627737	RPE1	viability after 9 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.2756281905483309	[863]	[167,294]	-2	hSpCas9	negative selection	1125146
88810476	88810499	16	-	26627737	RPE1	viability after 9 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.4798973676601588	[2840]	[542,759]	-3	hSpCas9	negative selection	1125147
88810541	88810564	16	-	26627737	RPE1	viability after 9 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7900133506650625	[1823]	[331,327]	-5	hSpCas9	negative selection	1125148
88811572	88811595	16	-	26627737	RPE1	viability after 9 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.33305433286774155	[132]	[58,43]	2	hSpCas9	negative selection	1125149
88811580	88811603	16	+	26627737	RPE1	viability after 9 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-1.2467836367144034	[1093]	[180,96]	-7	hSpCas9	negative selection	1125150
88809754	88809777	16	+	26627737	RPE1	viability after 12 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.18806742680944122	[427]	[79,184]	1	hSpCas9	negative selection	1207460
88810130	88810153	16	+	26627737	RPE1	viability after 12 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.4414057597803416	[863]	[49,298]	-3	hSpCas9	negative selection	1207461
88810476	88810499	16	-	26627737	RPE1	viability after 12 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-1.0156842754981472	[2840]	[445,304]	-6	hSpCas9	negative selection	1207462
88810541	88810564	16	-	26627737	RPE1	viability after 12 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.249677910961844	[1823]	[332,495]	-2	hSpCas9	negative selection	1207463
88811572	88811595	16	-	26627737	RPE1	viability after 12 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.9385601528761147	[132]	[50,86]	6	hSpCas9	negative selection	1207464
88811580	88811603	16	+	26627737	RPE1	viability after 12 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.8342130245315402	[1093]	[176,151]	-5	hSpCas9	negative selection	1207465
88809754	88809777	16	+	26627737	RPE1	viability after 15 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.43466290645947825	[427]	[28,147]	-3	hSpCas9	negative selection	1289775
88810130	88810153	16	+	26627737	RPE1	viability after 15 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.22158454699375907	[863]	[90,323]	-1	hSpCas9	negative selection	1289776
88810476	88810499	16	-	26627737	RPE1	viability after 15 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.19560926572255832	[2840]	[827,579]	-1	hSpCas9	negative selection	1289777
88810541	88810564	16	-	26627737	RPE1	viability after 15 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.4442347482154042	[1823]	[450,309]	-3	hSpCas9	negative selection	1289778
88811572	88811595	16	-	26627737	RPE1	viability after 15 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.0798382527546315	[132]	[0,33]	-6	hSpCas9	negative selection	1289779
88811580	88811603	16	+	26627737	RPE1	viability after 15 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.7481184822790259	[1093]	[141,224]	-5	hSpCas9	negative selection	1289780
88809754	88809777	16	+	26627737	RPE1	viability after 18 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.24935051507061878	[427]	[72,122]	-1	hSpCas9	negative selection	1372090
88810130	88810153	16	+	26627737	RPE1	viability after 18 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.2622082200623017	[863]	[191,196]	-2	hSpCas9	negative selection	1372091
88810476	88810499	16	-	26627737	RPE1	viability after 18 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.6910766637437966	[2840]	[456,493]	-4	hSpCas9	negative selection	1372092
88810541	88810564	16	-	26627737	RPE1	viability after 18 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.35329997592425266	[1823]	[452,312]	-2	hSpCas9	negative selection	1372093
88811572	88811595	16	-	26627737	RPE1	viability after 18 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.7027678923503853	[132]	[8,35]	-4	hSpCas9	negative selection	1372094
88811580	88811603	16	+	26627737	RPE1	viability after 18 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.7684943959432071	[1093]	[94,256]	-5	hSpCas9	negative selection	1372095
88809754	88809777	16	+	26627737	HeLa	viability after 8 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-1.4506837341702492	[328]	[156,12,12]	-9	hSpCas9	negative selection	1454405
88810130	88810153	16	+	26627737	HeLa	viability after 8 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	1.9900687753870325	[109]	[108,318,128]	9	hSpCas9	negative selection	1454406
88810476	88810499	16	-	26627737	HeLa	viability after 8 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.4006969893325796	[817]	[580,247,595]	3	hSpCas9	negative selection	1454407
88810541	88810564	16	-	26627737	HeLa	viability after 8 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	1.0854001186293054	[670]	[618,433,792]	8	hSpCas9	negative selection	1454408
88811572	88811595	16	-	26627737	HeLa	viability after 8 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.6704640281224747	[187]	[0,103,38]	-6	hSpCas9	negative selection	1454409
88811580	88811603	16	+	26627737	HeLa	viability after 8 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.4217919680797537	[130]	[163,46,39]	4	hSpCas9	negative selection	1454410
88809754	88809777	16	+	26627737	HeLa	viability after 12 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-2.037737567437281	[328]	[7,19,71]	-9	hSpCas9	negative selection	1536720
88810130	88810153	16	+	26627737	HeLa	viability after 12 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	2.210486630970673	[109]	[215,260,148]	9	hSpCas9	negative selection	1536721
88810476	88810499	16	-	26627737	HeLa	viability after 12 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.6633410000412681	[817]	[580,388,652]	5	hSpCas9	negative selection	1536722
88810541	88810564	16	-	26627737	HeLa	viability after 12 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.9645576620067234	[670]	[756,443,438]	7	hSpCas9	negative selection	1536723
88811572	88811595	16	-	26627737	HeLa	viability after 12 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.9859700069171238	[187]	[13,25,17]	-9	hSpCas9	negative selection	1536724
88811580	88811603	16	+	26627737	HeLa	viability after 12 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	1.3266237135173657	[130]	[180,160,63]	8	hSpCas9	negative selection	1536725
88809754	88809777	16	+	26627737	HeLa	viability after 15 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.7407117119874708	[328]	[145,44,45]	-6	hSpCas9	negative selection	1619035
88810130	88810153	16	+	26627737	HeLa	viability after 15 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	1.497030477420712	[109]	[145,117,113]	8	hSpCas9	negative selection	1619036
88810476	88810499	16	-	26627737	HeLa	viability after 15 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.6359622174374195	[817]	[389,804,345]	5	hSpCas9	negative selection	1619037
88810541	88810564	16	-	26627737	HeLa	viability after 15 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.5163084455105641	[670]	[224,609,334]	4	hSpCas9	negative selection	1619038
88811572	88811595	16	-	26627737	HeLa	viability after 15 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.3369990872597035	[187]	[2,84,0]	-8	hSpCas9	negative selection	1619039
88811580	88811603	16	+	26627737	HeLa	viability after 15 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	1.1273902800628948	[130]	[148,108,88]	7	hSpCas9	negative selection	1619040
88809754	88809777	16	+	26627737	HeLa	viability after 18 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.6913233024129508	[328]	[105,33,45]	-6	hSpCas9	negative selection	1701350
88810130	88810153	16	+	26627737	HeLa	viability after 18 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	1.440017081165269	[109]	[88,96,113]	8	hSpCas9	negative selection	1701351
88810476	88810499	16	-	26627737	HeLa	viability after 18 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.6294609912967779	[817]	[259,662,345]	5	hSpCas9	negative selection	1701352
88810541	88810564	16	-	26627737	HeLa	viability after 18 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.5207736369314423	[670]	[154,502,334]	4	hSpCas9	negative selection	1701353
88811572	88811595	16	-	26627737	HeLa	viability after 18 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.4051390487648794	[187]	[1,66,0]	-8	hSpCas9	negative selection	1701354
88811580	88811603	16	+	26627737	HeLa	viability after 18 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	1.0901304079472391	[130]	[95,87,88]	7	hSpCas9	negative selection	1701355
88809754	88809777	16	+	26627737	HCT116	viability after 6 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.9923542464863011	[780]	[169,1]	-5	hSpCas9	negative selection	1783665
88810130	88810153	16	+	26627737	HCT116	viability after 6 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.3623400761891813	[335]	[33,44]	-2	hSpCas9	negative selection	1783666
88810476	88810499	16	-	26627737	HCT116	viability after 6 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-1.5808337512169712	[1455]	[178,19]	-7	hSpCas9	negative selection	1783667
88810541	88810564	16	-	26627737	HCT116	viability after 6 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.5691560212361617	[2439]	[173,786]	3	hSpCas9	negative selection	1783668
88811572	88811595	16	-	26627737	HCT116	viability after 6 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.6252525487908371	[114]	[43,18]	3	hSpCas9	negative selection	1783669
88811580	88811603	16	+	26627737	HCT116	viability after 6 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	1.2351983782326768	[406]	[265,86]	6	hSpCas9	negative selection	1783670
88809754	88809777	16	+	26627737	HCT116	viability after 8 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-1.275345458109753	[299]	[56,105,41]	-9	hSpCas9	negative selection	1865980
88810130	88810153	16	+	26627737	HCT116	viability after 8 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.02902028202415602	[209]	[101,140,110]	0	hSpCas9	negative selection	1865981
88810476	88810499	16	-	26627737	HCT116	viability after 8 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.3523924257723483	[775]	[273,336,391]	-4	hSpCas9	negative selection	1865982
88810541	88810564	16	-	26627737	HCT116	viability after 8 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.21565450618113235	[803]	[342,348,450]	-2	hSpCas9	negative selection	1865983
88811572	88811595	16	-	26627737	HCT116	viability after 8 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-3.2083900420746954	[72]	[0,7,3]	-9	hSpCas9	negative selection	1865984
88811580	88811603	16	+	26627737	HCT116	viability after 8 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.9814764499061739	[263]	[68,82,68]	-8	hSpCas9	negative selection	1865985
88809754	88809777	16	+	26627737	HCT116	viability after 9 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.7165280088933177	[780]	[122,129]	-5	hSpCas9	negative selection	1948295
88810130	88810153	16	+	26627737	HCT116	viability after 9 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.17255581584450141	[335]	[37,150]	1	hSpCas9	negative selection	1948296
88810476	88810499	16	-	26627737	HCT116	viability after 9 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.5071939731369532	[1455]	[296,254]	-4	hSpCas9	negative selection	1948297
88810541	88810564	16	-	26627737	HCT116	viability after 9 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.346406916158194	[2439]	[482,76]	-7	hSpCas9	negative selection	1948298
88811572	88811595	16	-	26627737	HCT116	viability after 9 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.02829626087338788	[114]	[13,44]	0	hSpCas9	negative selection	1948299
88811580	88811603	16	+	26627737	HCT116	viability after 9 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.47732700521535243	[406]	[86,70]	-3	hSpCas9	negative selection	1948300
88809754	88809777	16	+	26627737	HCT116	viability after 12 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-1.5867822358110586	[299]	[71,62,20]	-9	hSpCas9	negative selection	2030610
88810130	88810153	16	+	26627737	HCT116	viability after 12 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.2898084187485359	[209]	[80,104,85]	-3	hSpCas9	negative selection	2030611
88810476	88810499	16	-	26627737	HCT116	viability after 12 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.14815875140940205	[775]	[443,394,258]	-1	hSpCas9	negative selection	2030612
88810541	88810564	16	-	26627737	HCT116	viability after 12 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5280421432193059	[803]	[219,314,350]	-5	hSpCas9	negative selection	2030613
88811572	88811595	16	-	26627737	HCT116	viability after 12 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.9374499459718946	[72]	[19,15,23]	-7	hSpCas9	negative selection	2030614
88811580	88811603	16	+	26627737	HCT116	viability after 12 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.7944055486168167	[263]	[69,126,44]	-7	hSpCas9	negative selection	2030615
88809754	88809777	16	+	26627737	HCT116	viability after 15 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-1.3018282384601791	[299]	[73,53,81]	-8	hSpCas9	negative selection	2112925
88810130	88810153	16	+	26627737	HCT116	viability after 15 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.013350088584305642	[209]	[89,154,109]	0	hSpCas9	negative selection	2112926
88810476	88810499	16	-	26627737	HCT116	viability after 15 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.3988043471493793	[775]	[390,331,297]	-4	hSpCas9	negative selection	2112927
88810541	88810564	16	-	26627737	HCT116	viability after 15 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6506698389086113	[803]	[419,293,184]	-6	hSpCas9	negative selection	2112928
88811572	88811595	16	-	26627737	HCT116	viability after 15 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.5076512476133432	[72]	[13,7,0]	-9	hSpCas9	negative selection	2112929
88811580	88811603	16	+	26627737	HCT116	viability after 15 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-1.2333813386107253	[263]	[53,58,78]	-8	hSpCas9	negative selection	2112930
88809754	88809777	16	+	26627737	HCT116	viability after 18 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-1.7482595916960577	[299]	[69,27,31]	-8	hSpCas9	negative selection	2195240
88810130	88810153	16	+	26627737	HCT116	viability after 18 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.08036966565326237	[209]	[99,101,120]	0	hSpCas9	negative selection	2195241
88810476	88810499	16	-	26627737	HCT116	viability after 18 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.3708923972578475	[775]	[285,268,317]	-3	hSpCas9	negative selection	2195242
88810541	88810564	16	-	26627737	HCT116	viability after 18 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.2349126842509497	[803]	[175,323,498]	-2	hSpCas9	negative selection	2195243
88811572	88811595	16	-	26627737	HCT116	viability after 18 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.1605245968118734	[72]	[0,7,14]	-9	hSpCas9	negative selection	2195244
88811580	88811603	16	+	26627737	HCT116	viability after 18 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-1.0769029777993102	[263]	[54,49,77]	-7	hSpCas9	negative selection	2195245
88811547	88811570	16	+	24336569	HL60	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.3017940555084519	[465]	[799]	-3	hSpCas9	negative selection	2248298
88811572	88811595	16	-	24336569	HL60	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.3596570231544345	[691]	[1878]	3	hSpCas9	negative selection	2248299
88811580	88811603	16	+	24336569	HL60	viability	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.8838264852471425	[1225]	[1405]	-7	hSpCas9	negative selection	2248300
88811590	88811613	16	+	24336569	HL60	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.21295944293130176	[1397]	[3428]	2	hSpCas9	negative selection	2248301
88811605	88811628	16	+	24336569	HL60	viability	GCCGATGGCGGCGCGGAAGGAGG	APRT	ENSG00000198931	0.3422821284858756	[639]	[1716]	3	hSpCas9	negative selection	2248302
88811634	88811657	16	-	24336569	HL60	viability	GGACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	-0.3198819458914196	[429]	[728]	-3	hSpCas9	negative selection	2248303
88811814	88811837	16	+	24336569	HL60	viability	GTGCACCTGAATACCACGCCTGG	APRT	ENSG00000198931	1.003190574205111	[483]	[2052]	7	hSpCas9	negative selection	2248304
88811864	88811887	16	-	24336569	HL60	viability	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	-0.537227537679333	[490]	[715]	-5	hSpCas9	negative selection	2248305
88811873	88811896	16	+	24336569	HL60	viability	AACCAGCTGCAGCTCGGAGTCGG	APRT	ENSG00000198931	-0.34282678548665957	[1034]	[1726]	-3	hSpCas9	negative selection	2248306
88811879	88811902	16	+	24336569	HL60	viability	CTGCAGCTCGGAGTCGGCCATGG	APRT	ENSG00000198931	-0.691517582312883	[492]	[645]	-6	hSpCas9	negative selection	2248307
88811547	88811570	16	+	24336569	KBM7	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.0937445884653693	[357]	[1041]	0	hSpCas9	negative selection	2315475
88811572	88811595	16	-	24336569	KBM7	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.7875462626175403	[673]	[1064]	-6	hSpCas9	negative selection	2315476
88811580	88811603	16	+	24336569	KBM7	viability	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-1.1473831701589585	[708]	[872]	-7	hSpCas9	negative selection	2315477
88811590	88811613	16	+	24336569	KBM7	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.8196192903322509	[1189]	[1838]	-6	hSpCas9	negative selection	2315478
88811605	88811628	16	+	24336569	KBM7	viability	GCCGATGGCGGCGCGGAAGGAGG	APRT	ENSG00000198931	-0.06152076424180464	[263]	[689]	0	hSpCas9	negative selection	2315479
88811634	88811657	16	-	24336569	KBM7	viability	GGACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	-0.6873706018706011	[430]	[729]	-5	hSpCas9	negative selection	2315480
88811814	88811837	16	+	24336569	KBM7	viability	GTGCACCTGAATACCACGCCTGG	APRT	ENSG00000198931	0.12244207060079054	[549]	[1632]	1	hSpCas9	negative selection	2315481
88811864	88811887	16	-	24336569	KBM7	viability	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	-0.893801401013252	[264]	[388]	-6	hSpCas9	negative selection	2315482
88811873	88811896	16	+	24336569	KBM7	viability	AACCAGCTGCAGCTCGGAGTCGG	APRT	ENSG00000198931	-0.034840813359626854	[627]	[1671]	0	hSpCas9	negative selection	2315483
88811879	88811902	16	+	24336569	KBM7	viability	CTGCAGCTCGGAGTCGGCCATGG	APRT	ENSG00000198931	-1.0149690678220888	[611]	[825]	-6	hSpCas9	negative selection	2315484
88811864	88811887	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	0.32086633009951604	[3,3]	[3,4]	6	hSpCas9	positive selection	2971075
88811599	88811622	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	0.18539143309431338	[2,1]	[2,1]	4	hSpCas9	positive selection	2971076
88811584	88811607	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	0.5007214085881874	[4,4]	[4,6]	8	hSpCas9	positive selection	2971077
88810541	88810564	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.9324694443326337	[3,3]	[1,0]	-9	hSpCas9	positive selection	2971078
88811864	88811887	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	-0.006621101065743186	[3,3]	[2,1]	0	hSpCas9	positive selection	3038933
88811599	88811622	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	-0.6988206997016062	[2,2]	[1,0]	-8	hSpCas9	positive selection	3038934
88811584	88811607	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	-0.1930736182386279	[4,4]	[3,2]	-3	hSpCas9	positive selection	3038935
88810541	88810564	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.33181030928342786	[3,3]	[2,0]	-5	hSpCas9	positive selection	3038936
88811547	88811570		+	24336571	A375	resistance to PLX after 7 days	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.02506276049577494	[20,17]	[18,18]	0	hSpCas9	positive selection	3124686
88810541	88810564		-	24336571	A375	resistance to PLX after 7 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.2800928490782376	[10,11]	[14,12]	7	hSpCas9	positive selection	3124697
88810477	88810500		-	24336571	A375	resistance to PLX after 7 days	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.17774226181452646	[8,9]	[7,7]	-5	hSpCas9	positive selection	3124708
88811549	88811572		-	24336571	A375	resistance to PLX after 7 days	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.45055599414871983	[35,32]	[43,49]	9	hSpCas9	positive selection	3124719
88811547	88811570		+	24336571	A375	resistance to PLX after 14 days	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.19725497755289156	[10,14]	[5,3]	-2	hSpCas9	positive selection	3182479
88810541	88810564		-	24336571	A375	resistance to PLX after 14 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.22230895221293168	[8,9]	[2,2]	-2	hSpCas9	positive selection	3182490
88810477	88810500		-	24336571	A375	resistance to PLX after 14 days	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.5175132952623019	[9,4]	[1,1]	-6	hSpCas9	positive selection	3182501
88811549	88811572		-	24336571	A375	resistance to PLX after 14 days	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	1.6284926668284747	[27,36]	[49,42]	9	hSpCas9	positive selection	3182512
88811547	88811570		+	24336571	A375	viability after 7 days	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.13511065929181	[22]	[20,17]	-2	hSpCas9	negative selection	3240272
88810541	88810564		-	24336571	A375	viability after 7 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6659457189849605	[19]	[10,11]	-7	hSpCas9	negative selection	3240283
88810477	88810500		-	24336571	A375	viability after 7 days	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.07768302812380806	[10]	[8,9]	-1	hSpCas9	negative selection	3240294
88811549	88811572		-	24336571	A375	viability after 7 days	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.47878349018473454	[50]	[35,32]	-6	hSpCas9	negative selection	3240305
88811547	88811570		+	24336571	A375	viability after 14 days	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.6933250284776881	[22]	[10,14]	-7	hSpCas9	negative selection	3298065
88810541	88810564		-	24336571	A375	viability after 14 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.9571893888294765	[19]	[8,9]	-8	hSpCas9	negative selection	3298076
88810477	88810500		-	24336571	A375	viability after 14 days	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.3854587266660308	[10]	[9,4]	-4	hSpCas9	negative selection	3298087
88811549	88811572		-	24336571	A375	viability after 14 days	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.561424579158365	[50]	[27,36]	-6	hSpCas9	negative selection	3298098
88811547	88811570	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.3359123243230635	[208,176]	[0,0]	-2	hSpCas9	positive selection	3337119
88811549	88811572	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.22179358074001385	[165,190]	[0,0]	-1	hSpCas9	positive selection	3337120
88810093	88810116	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.46032781387104155	[209,210]	[0,0]	-3	hSpCas9	positive selection	3337121
88810477	88810500	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.2915419267837481	[124,124]	[0,0]	1	hSpCas9	positive selection	3356367
88810091	88810114	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3356368
88810541	88810564	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6495643841626835	[239,239]	[0,0]	-4	hSpCas9	positive selection	3356369
88811864	88811887	16	-	26780180	HT29	viability (Avana library 4 designs)	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	1.0274625549822	[]	[]	4	hSpCas9	negative selection	3407185
88811598	88811621	16	+	26780180	HT29	viability (Avana library 4 designs)	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	2.44540364010584	[]	[]	8	hSpCas9	negative selection	3407186
88811583	88811606	16	+	26780180	HT29	viability (Avana library 4 designs)	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	1.03657239016644	[]	[]	4	hSpCas9	negative selection	3407187
88810541	88810564	16	-	26780180	HT29	viability (Avana library 4 designs)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	1.71597735202416	[]	[]	6	hSpCas9	negative selection	3407188
88811864	88811887	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	-0.441200826322316	[]	[]	0	hSpCas9	negative selection	3480107
88811583	88811606	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	3.73800307644019	[]	[]	6	hSpCas9	negative selection	3480108
88810541	88810564	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	2.66269953592506	[]	[]	4	hSpCas9	negative selection	3480109
88811598	88811621	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	6.9103550042066	[]	[]	9	hSpCas9	negative selection	3480110
88811610	88811633	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCGGCGCGGAAGGAGGCGGGG	APRT	ENSG00000198931	0.572885106519677	[]	[]	0	hSpCas9	negative selection	3480111
88811571	88811594	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCTGAAGGCGACCCACGGGG	APRT	ENSG00000198931	4.13208257376724	[]	[]	6	hSpCas9	negative selection	3480112
88811864	88811887	16	-	26780180	A375	viability (Avana lentiGuide)	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	9.11446392918132	[]	[]	6	hSpCas9	negative selection	3588766
88811583	88811606	16	+	26780180	A375	viability (Avana lentiGuide)	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	2.76568152178481	[]	[]	3	hSpCas9	negative selection	3588767
88810541	88810564	16	-	26780180	A375	viability (Avana lentiGuide)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	7.78517454750531	[]	[]	6	hSpCas9	negative selection	3588768
88811598	88811621	16	+	26780180	A375	viability (Avana lentiGuide)	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	-1.26862007198142	[]	[]	-2	hSpCas9	negative selection	3588769
88811610	88811633	16	+	26780180	A375	viability (Avana lentiGuide)	TGGCGGCGCGGAAGGAGGCGGGG	APRT	ENSG00000198931	13.3556200495821	[]	[]	7	hSpCas9	negative selection	3588770
88811571	88811594	16	-	26780180	A375	viability (Avana lentiGuide)	ACACCTGAAGGCGACCCACGGGG	APRT	ENSG00000198931	0.613890830193332	[]	[]	0	hSpCas9	negative selection	3588771
88811864	88811887	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	0.1718058839925094	[4]	[5,4]	5	hSpCas9	positive selection	3697425
88811583	88811606	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	0.14616890406501257	[5]	[6,5]	4	hSpCas9	positive selection	3697426
88810541	88810564	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.17028482551464164	[4]	[3,3]	-3	hSpCas9	positive selection	3697427
88811598	88811621	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	0.4641817192398775	[4]	[6,5]	9	hSpCas9	positive selection	3697428
88811610	88811633	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCGGCGCGGAAGGAGGCGGGG	APRT	ENSG00000198931	0.08512146871109266	[3]	[4,3]	2	hSpCas9	positive selection	3697429
88811571	88811594	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCTGAAGGCGACCCACGGGG	APRT	ENSG00000198931	-0.08100272491189325	[4]	[4,2]	-1	hSpCas9	positive selection	3697430
88811864	88811887	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGCAGCTGGTTGAGCAGCGG	APRT	ENSG00000198931	-0.03464391665747304	[5]	[4,4]	0	hSpCas9	positive selection	3806032
88811583	88811606	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTCAGGTGTCGCGCCAGGAGG	APRT	ENSG00000198931	0.14628528149198539	[6]	[6,6]	3	hSpCas9	positive selection	3806033
88810541	88810564	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5960426476069063	[5]	[0,4]	-6	hSpCas9	positive selection	3806034
88811598	88811621	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGAGGCCGATGGCGGCGCGG	APRT	ENSG00000198931	0.31082395915981065	[3]	[3,4]	8	hSpCas9	positive selection	3806035
88811610	88811633	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCGGCGCGGAAGGAGGCGGGG	APRT	ENSG00000198931	-0.44192534865460853	[4]	[0,4]	-5	hSpCas9	positive selection	3806036
88811571	88811594	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCTGAAGGCGACCCACGGGG	APRT	ENSG00000198931	-0.5046184334008503	[4]	[1,2]	-6	hSpCas9	positive selection	3806037
88810093	88810116	16	+	26780180	A375	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	2.05604537252898	[]	[]	9	hSpCas9	negative selection	3914299
88810091	88810114	16	-	26780180	A375	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.957879901625865	[]	[]	4	hSpCas9	negative selection	3914300
88811547	88811570	16	+	26780180	A375	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	1.13089439256628	[]	[]	5	hSpCas9	negative selection	3914301
88810541	88810564	16	-	26780180	A375	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	1.97847627871518	[]	[]	9	hSpCas9	negative selection	3914302
88810477	88810500	16	-	26780180	A375	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	1.32169256632288	[]	[]	7	hSpCas9	negative selection	3914303
88811549	88811572	16	-	26780180	A375	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	1.69927135860922	[]	[]	9	hSpCas9	negative selection	3914304
88810093	88810116	16	+	26780180	HT29	viability (GeCKOv2 library)	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	1.83258508727019	[]	[]	8	hSpCas9	negative selection	4022265
88810091	88810114	16	-	26780180	HT29	viability (GeCKOv2 library)	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	1.17930417289735	[]	[]	6	hSpCas9	negative selection	4022266
88811547	88811570	16	+	26780180	HT29	viability (GeCKOv2 library)	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.933842129941862	[]	[]	4	hSpCas9	negative selection	4022267
88810541	88810564	16	-	26780180	HT29	viability (GeCKOv2 library)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	1.70646567819458	[]	[]	8	hSpCas9	negative selection	4022268
88810477	88810500	16	-	26780180	HT29	viability (GeCKOv2 library)	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	1.141491370327	[]	[]	5	hSpCas9	negative selection	4022269
88811549	88811572	16	-	26780180	HT29	viability (GeCKOv2 library)	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	1.55792956118167	[]	[]	8	hSpCas9	negative selection	4022270
88811547	88811570	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.06026693634058847	[4]	[3,2]	-1	hSpCas9	positive selection	4148762
88810541	88810564	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.35694604289310483	[4]	[2,1]	-7	hSpCas9	positive selection	4148773
88810477	88810500	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.5867338331104963	[3]	[1,0]	-9	hSpCas9	positive selection	4148784
88811549	88811572	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.33043794219878775	[4]	[2,5]	7	hSpCas9	positive selection	4148795
88811547	88811570	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.5170931622796839	[4]	[0,1,1,3]	3	hSpCas9	positive selection	4212784
88810541	88810564	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7371764308918675	[3]	[1,0,0,0]	-8	hSpCas9	positive selection	4212795
88810477	88810500	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.6028060861405424	[2]	[4,0,4,0]	4	hSpCas9	positive selection	4212806
88811549	88811572	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.2254945276013509	[5]	[5,2,4,0]	1	hSpCas9	positive selection	4212817
88811547	88811570	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.2106316371103984	[3]	[2,1]	-4	hSpCas9	positive selection	4256273
88811549	88811572	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.061447770910933064	[3]	[2,2]	-1	hSpCas9	positive selection	4256274
88810093	88810116	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.31489238916295925	[4]	[2,2]	-6	hSpCas9	positive selection	4256275
88810477	88810500	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.2047091115203137	[2]	[2,0]	-4	hSpCas9	positive selection	4320557
88810091	88810114	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.38217619195751606	[2]	[1,0]	-7	hSpCas9	positive selection	4320558
88810541	88810564	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.0006338847280652482	[3]	[2,2]	0	hSpCas9	positive selection	4320559
88810477	88810499	16	-	27760321	OCIAML3	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.28428571393589364	[504,396]	[368,501]	3	hSpCas9	negative selection	4378855
88810541	88810563	16	-	27760321	OCIAML3	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6261268148899737	[589,419]	[214,302]	-6	hSpCas9	negative selection	4378856
88811549	88811571	16	-	27760321	OCIAML3	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.5975415497766919	[1330,1003]	[436,808]	-5	hSpCas9	negative selection	4378857
88811581	88811603	16	+	27760321	OCIAML3	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.21278338906355176	[782,677]	[540,815]	2	hSpCas9	negative selection	4378858
88811634	88811656	16	-	27760321	OCIAML3	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.09035123397374112	[1186,1050]	[762,1147]	1	hSpCas9	negative selection	4378859
88810477	88810499	16	-	27760321	OCIAML2	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.3614256508720206	[504,396]	[241,334]	-4	hSpCas9	negative selection	4462318
88810541	88810563	16	-	27760321	OCIAML2	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.051095564867403	[589,419]	[141,264]	-7	hSpCas9	negative selection	4462319
88811549	88811571	16	-	27760321	OCIAML2	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.6148023208100574	[1330,1003]	[552,688]	-6	hSpCas9	negative selection	4462320
88811581	88811603	16	+	27760321	OCIAML2	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.08529745728940508	[782,677]	[514,608]	-1	hSpCas9	negative selection	4462321
88811634	88811656	16	-	27760321	OCIAML2	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.023395170241292007	[1186,1050]	[892,951]	0	hSpCas9	negative selection	4462322
88810477	88810499	16	-	27760321	MV411	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.5606780965181681	[504,396]	[269,95]	-4	hSpCas9	negative selection	4545781
88810541	88810563	16	-	27760321	MV411	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.04925076706190676	[589,419]	[165,547]	0	hSpCas9	negative selection	4545782
88811549	88811571	16	-	27760321	MV411	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.19574158095128813	[1330,1003]	[860,375]	-1	hSpCas9	negative selection	4545783
88811581	88811603	16	+	27760321	MV411	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.3117142368223632	[782,677]	[543,675]	2	hSpCas9	negative selection	4545784
88811634	88811656	16	-	27760321	MV411	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	-0.32572282915932305	[1186,1050]	[331,972]	-2	hSpCas9	negative selection	4545785
88810477	88810499	16	-	27760321	HL60	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.3659339917207576	[504,396]	[250,318]	-4	hSpCas9	negative selection	4629244
88810541	88810563	16	-	27760321	HL60	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.004421129447350264	[589,419]	[373,446]	0	hSpCas9	negative selection	4629245
88811549	88811571	16	-	27760321	HL60	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.6655645359531004	[1330,1003]	[639,549]	-6	hSpCas9	negative selection	4629246
88811581	88811603	16	+	27760321	HL60	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.0686353037545494	[782,677]	[695,547]	0	hSpCas9	negative selection	4629247
88811634	88811656	16	-	27760321	HL60	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	-0.22528075894633326	[1186,1050]	[899,653]	-3	hSpCas9	negative selection	4629248
88810477	88810499	16	-	27760321	HT1080	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-1.8083456146420573	[396,309]	[12,69]	-6	hSpCas9	negative selection	4712707
88810541	88810563	16	-	27760321	HT1080	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.57900177464181	[419,327]	[4,98]	-5	hSpCas9	negative selection	4712708
88811549	88811571	16	-	27760321	HT1080	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.8027043252045124	[1003,783]	[112,303]	-3	hSpCas9	negative selection	4712709
88811581	88811603	16	+	27760321	HT1080	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.0232560813720879	[677,528]	[237,234]	0	hSpCas9	negative selection	4712710
88811634	88811656	16	-	27760321	HT1080	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	-0.6262326278478749	[1050,819]	[197,288]	-3	hSpCas9	negative selection	4712711
88810477	88810499	16	-	27760321	HT29	viability after 7 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.4640969508363846	[396,309]	[493,864,505]	7	hSpCas9	negative selection	4796170
88810541	88810563	16	-	27760321	HT29	viability after 7 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.1698479869599992	[419,327]	[694,501,449]	2	hSpCas9	negative selection	4796171
88811549	88811571	16	-	27760321	HT29	viability after 7 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.05641550032667175	[1003,783]	[1478,979,914]	-1	hSpCas9	negative selection	4796172
88811581	88811603	16	+	27760321	HT29	viability after 7 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.3387598286877981	[677,528]	[779,455,626]	-5	hSpCas9	negative selection	4796173
88811634	88811656	16	-	27760321	HT29	viability after 7 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.2807587658321229	[1050,819]	[1406,1167,1787]	4	hSpCas9	negative selection	4796174
88810477	88810499	16	-	27760321	HT29	viability after 25 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.2125600741113927	[396,309]	[479,393,535]	2	hSpCas9	negative selection	4879633
88810541	88810563	16	-	27760321	HT29	viability after 25 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7314170209541425	[419,327]	[186,274,320]	-6	hSpCas9	negative selection	4879634
88811549	88811571	16	-	27760321	HT29	viability after 25 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.19662696744888142	[1003,783]	[893,810,976]	-2	hSpCas9	negative selection	4879635
88811581	88811603	16	+	27760321	HT29	viability after 25 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.018745236100540574	[677,528]	[653,733,651]	0	hSpCas9	negative selection	4879636
88811634	88811656	16	-	27760321	HT29	viability after 25 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.33222737281073766	[1050,819]	[1333,1498,1186]	3	hSpCas9	negative selection	4879637
88810477	88810499	16	-	27760321	HT29	viability after 22 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.08160721160192455	[396,309]	[384,443,469]	0	hSpCas9	negative selection	4963096
88810541	88810563	16	-	27760321	HT29	viability after 22 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6337769960718214	[419,327]	[211,323,301]	-5	hSpCas9	negative selection	4963097
88811549	88811571	16	-	27760321	HT29	viability after 22 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3558956197997897	[1003,783]	[809,771,840]	-4	hSpCas9	negative selection	4963098
88811581	88811603	16	+	27760321	HT29	viability after 22 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.20325199090580892	[677,528]	[543,627,647]	-2	hSpCas9	negative selection	4963099
88811634	88811656	16	-	27760321	HT29	viability after 22 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.3314306368112716	[1050,819]	[941,1638,1513]	3	hSpCas9	negative selection	4963100
88810477	88810499	16	-	27760321	HT29	viability after 19 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.044386026232236725	[396,309]	[421,383,443]	0	hSpCas9	negative selection	5046559
88810541	88810563	16	-	27760321	HT29	viability after 19 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.2117778713716199	[419,327]	[623,235,277]	-2	hSpCas9	negative selection	5046560
88811549	88811571	16	-	27760321	HT29	viability after 19 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.020339907707547233	[1003,783]	[1038,1449,636]	0	hSpCas9	negative selection	5046561
88811581	88811603	16	+	27760321	HT29	viability after 19 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.03773360946098203	[677,528]	[655,499,851]	0	hSpCas9	negative selection	5046562
88811634	88811656	16	-	27760321	HT29	viability after 19 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.6618002670683334	[1050,819]	[1527,1691,1833]	6	hSpCas9	negative selection	5046563
88810477	88810499	16	-	27760321	HT29	viability after 16 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.0003749587048297101	[396,309]	[456,202,536]	0	hSpCas9	negative selection	5130022
88810541	88810563	16	-	27760321	HT29	viability after 16 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.26592606483744835	[419,327]	[225,479,322]	-3	hSpCas9	negative selection	5130023
88811549	88811571	16	-	27760321	HT29	viability after 16 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.07979244638097893	[1003,783]	[1109,1102,961]	0	hSpCas9	negative selection	5130024
88811581	88811603	16	+	27760321	HT29	viability after 16 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.021119669223721327	[677,528]	[469,456,1055]	0	hSpCas9	negative selection	5130025
88811634	88811656	16	-	27760321	HT29	viability after 16 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.3251847169465787	[1050,819]	[1368,1423,1142]	3	hSpCas9	negative selection	5130026
88810477	88810499	16	-	27760321	HT29	viability after 13 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.04606390723855114	[396,309]	[233,492,460]	0	hSpCas9	negative selection	5213485
88810541	88810563	16	-	27760321	HT29	viability after 13 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.2612010567966063	[419,327]	[332,371,379]	-3	hSpCas9	negative selection	5213486
88811549	88811571	16	-	27760321	HT29	viability after 13 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3475734327114709	[1003,783]	[689,897,854]	-4	hSpCas9	negative selection	5213487
88811581	88811603	16	+	27760321	HT29	viability after 13 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.06896585401056088	[677,528]	[867,570,761]	0	hSpCas9	negative selection	5213488
88811634	88811656	16	-	27760321	HT29	viability after 13 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.35802771051895976	[1050,819]	[1563,1435,1184]	4	hSpCas9	negative selection	5213489
88810477	88810499	16	-	27760321	HT29	viability after 10 days	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.21135493205561642	[396,309]	[499,676,363]	3	hSpCas9	negative selection	5296948
88810541	88810563	16	-	27760321	HT29	viability after 10 days	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.09149357127508817	[419,327]	[282,561,645]	1	hSpCas9	negative selection	5296949
88811549	88811571	16	-	27760321	HT29	viability after 10 days	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.24888053045376202	[1003,783]	[909,892,1011]	-3	hSpCas9	negative selection	5296950
88811581	88811603	16	+	27760321	HT29	viability after 10 days	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.1079883862387877	[677,528]	[546,940,617]	-1	hSpCas9	negative selection	5296951
88811634	88811656	16	-	27760321	HT29	viability after 10 days	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.3875765176697359	[1050,819]	[1777,1442,1363]	5	hSpCas9	negative selection	5296952
88810477	88810499	16	-	27760321	MOLM13	viability	CTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.9911530840074464	[504,396]	[23,214]	-5	hSpCas9	negative selection	5380411
88810541	88810563	16	-	27760321	MOLM13	viability	TGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.8541346801016616	[589,419]	[84,71]	-7	hSpCas9	negative selection	5380412
88811549	88811571	16	-	27760321	MOLM13	viability	GCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.017481860622451606	[1330,1003]	[1049,300]	0	hSpCas9	negative selection	5380413
88811581	88811603	16	+	27760321	MOLM13	viability	CGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.23853622219007087	[782,677]	[409,295]	-2	hSpCas9	negative selection	5380414
88811634	88811656	16	-	27760321	MOLM13	viability	GACATCTCGCCCGTCCTGAAGG	APRT	ENSG00000198931	0.09981230237740846	[1186,1050]	[521,805]	0	hSpCas9	negative selection	5380415
88811520	88811543	16	+	27661255	K562	viability	GCGCCCTAGATGCGGCCACTGGG	APRT	ENSG00000198931	0.037226419932318955	[911,995]	[824,742]	1	dCas9-KRAB	negative selection	5462930
88811678	88811701	16	+	27661255	K562	viability	GTGACGCCGGGGCCGAAGGAGGG	APRT	ENSG00000198931	0.08774012596645786	[1791,1785]	[1670,1388]	3	dCas9-KRAB	negative selection	5462931
88811485	88811508	16	-	27661255	K562	viability	GCGCGCCGAGGGCAGCACGTGGG	APRT	ENSG00000198931	0.055362703507774835	[418,367]	[355,302]	2	dCas9-KRAB	negative selection	5462932
88811523	88811546	16	-	27661255	K562	viability	GTGCCCAGTGGCCGCATCTAGGG	APRT	ENSG00000198931	0.04585567155201198	[1860,2000]	[1823,1390]	1	dCas9-KRAB	negative selection	5462933
88811547	88811570	16	+	27260156	BXPC3	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.06281178984749747	[664]	[844,546,692,823]	1	hSpCas9	negative selection	5528733
88811549	88811572	16	-	27260156	BXPC3	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.26615616396109565	[757]	[512,644,705,802]	-6	hSpCas9	negative selection	5528734
88810093	88810116	16	+	27260156	BXPC3	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.015616823339672736	[1051]	[1051,1063,1031,1216]	0	hSpCas9	negative selection	5528735
88810477	88810500	16	-	27260156	BXPC3	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.26309163971384564	[304]	[237,240,301,287]	-5	hSpCas9	negative selection	5593017
88810091	88810114	16	-	27260156	BXPC3	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.16687227034727137	[234]	[198,172,182,337]	-4	hSpCas9	negative selection	5593018
88810541	88810564	16	-	27260156	BXPC3	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.3353781067267571	[671]	[452,448,510,865]	-6	hSpCas9	negative selection	5593019
88811547	88811570	16	+	27260156	A673	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.1671761177028372	[664]	[818,655,733,643]	-4	hSpCas9	negative selection	5649984
88811549	88811572	16	-	27260156	A673	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.2496299871694152	[757]	[849,751,707,760]	-6	hSpCas9	negative selection	5649985
88810093	88810116	16	+	27260156	A673	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.1162707921904782	[1051]	[1251,944,1216,1265]	-3	hSpCas9	negative selection	5649986
88810477	88810500	16	-	27260156	A673	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.23668959832329073	[304]	[317,305,258,363]	-5	hSpCas9	negative selection	5714268
88810091	88810114	16	-	27260156	A673	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.3034249691719417	[234]	[211,249,187,263]	-6	hSpCas9	negative selection	5714269
88810541	88810564	16	-	27260156	A673	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6589509708610798	[671]	[555,495,513,480]	-9	hSpCas9	negative selection	5714270
88811547	88811570	16	+	27260156	A375	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.19544242656919836	[664]	[670,777,805,491]	-3	hSpCas9	negative selection	5771235
88811549	88811572	16	-	27260156	A375	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.1108711364928957	[757]	[780,959,924,649]	-2	hSpCas9	negative selection	5771236
88810093	88810116	16	+	27260156	A375	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.23273044268330878	[1051]	[1115,1318,1030,782]	-3	hSpCas9	negative selection	5771237
88810477	88810500	16	-	27260156	A375	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.49572366015090585	[304]	[263,193,322,223]	-6	hSpCas9	negative selection	5835519
88810091	88810114	16	-	27260156	A375	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.4655705921469948	[234]	[234,129,294,132]	-6	hSpCas9	negative selection	5835520
88810541	88810564	16	-	27260156	A375	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.2874615090097965	[671]	[406,267,335,272]	-9	hSpCas9	negative selection	5835521
88811547	88811570	16	+	27260156	COLO741	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.05695959507845927	[664]	[860,980,624]	-1	hSpCas9	negative selection	5892486
88811549	88811572	16	-	27260156	COLO741	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.1446131196829581	[757]	[843,906,872]	-3	hSpCas9	negative selection	5892487
88810093	88810116	16	+	27260156	COLO741	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.14179280613872858	[1051]	[1502,1499,1446]	3	hSpCas9	negative selection	5892488
88810477	88810500	16	-	27260156	COLO741	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.15772080441154646	[304]	[349,301,391]	-3	hSpCas9	negative selection	5956770
88810091	88810114	16	-	27260156	COLO741	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.4522314587130325	[234]	[256,281,128]	-7	hSpCas9	negative selection	5956771
88810541	88810564	16	-	27260156	COLO741	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.8660391462613077	[671]	[531,410,473]	-9	hSpCas9	negative selection	5956772
88811547	88811570	16	+	27260156	CAL120	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.3601090554154833	[664]	[628,515,783]	-5	hSpCas9	negative selection	6013737
88811549	88811572	16	-	27260156	CAL120	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.20590123073845623	[757]	[1000,851,630]	-3	hSpCas9	negative selection	6013738
88810093	88810116	16	+	27260156	CAL120	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.06801992439101534	[1051]	[1800,891,1137]	-1	hSpCas9	negative selection	6013739
88810477	88810500	16	-	27260156	CAL120	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.4655159652037526	[304]	[410,160,272]	-6	hSpCas9	negative selection	6078021
88810091	88810114	16	-	27260156	CAL120	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.3442703135348604	[234]	[154,147,373]	-5	hSpCas9	negative selection	6078022
88810541	88810564	16	-	27260156	CAL120	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.013126985657389	[671]	[496,385,372]	-8	hSpCas9	negative selection	6078023
88811547	88811570	16	+	27260156	CADOES1	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.18270307894826443	[664]	[432,527,594,626]	-3	hSpCas9	negative selection	6134988
88811549	88811572	16	-	27260156	CADOES1	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3016847388704343	[757]	[564,546,470,709]	-5	hSpCas9	negative selection	6134989
88810093	88810116	16	+	27260156	CADOES1	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.03846316716741227	[1051]	[915,936,769,1196]	0	hSpCas9	negative selection	6134990
88810477	88810500	16	-	27260156	CADOES1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.20420379710489378	[304]	[211,193,252,328]	-4	hSpCas9	negative selection	6199272
88810091	88810114	16	-	27260156	CADOES1	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.2908827758310655	[234]	[278,112,174,145]	-5	hSpCas9	negative selection	6199273
88810541	88810564	16	-	27260156	CADOES1	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6518654667384735	[671]	[453,341,444,347]	-8	hSpCas9	negative selection	6199274
88811547	88811570	16	+	27260156	EWS502	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.29438489392275224	[664]	[586,566,577,560]	-5	hSpCas9	negative selection	6256239
88811549	88811572	16	-	27260156	EWS502	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.18355168069567074	[757]	[760,516,667,892]	-3	hSpCas9	negative selection	6256240
88810093	88810116	16	+	27260156	EWS502	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.019049632429160468	[1051]	[970,985,1156,1445]	0	hSpCas9	negative selection	6256241
88810477	88810500	16	-	27260156	EWS502	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.2371673794724497	[304]	[308,262,277,238]	-4	hSpCas9	negative selection	6320523
88810091	88810114	16	-	27260156	EWS502	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.027130596184566258	[234]	[242,243,265,221]	0	hSpCas9	negative selection	6320524
88810541	88810564	16	-	27260156	EWS502	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.8498074729050278	[671]	[274,292,223,833]	-8	hSpCas9	negative selection	6320525
88811547	88811570	16	+	27260156	EW8	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.028779208816044677	[664]	[514,540,564,569]	0	hSpCas9	negative selection	6377490
88811549	88811572	16	-	27260156	EW8	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.10444592649244955	[757]	[763,530,494,887]	2	hSpCas9	negative selection	6377491
88810093	88810116	16	+	27260156	EW8	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.29583085818791566	[1051]	[1156,933,739,1414]	5	hSpCas9	negative selection	6377492
88810477	88810500	16	-	27260156	EW8	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.4442144482398487	[304]	[238,150,165,178]	-7	hSpCas9	negative selection	6441774
88810091	88810114	16	-	27260156	EW8	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.08235098636900107	[234]	[287,161,185,181]	1	hSpCas9	negative selection	6441775
88810541	88810564	16	-	27260156	EW8	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.29172247036976234	[671]	[524,511,251,530]	-5	hSpCas9	negative selection	6441776
88811547	88811570	16	+	27260156	CORL105	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.2573765247972679	[664]	[636,597,780,609]	-5	hSpCas9	negative selection	6498741
88811549	88811572	16	-	27260156	CORL105	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.2857463215659878	[757]	[782,690,726,712]	-5	hSpCas9	negative selection	6498742
88810093	88810116	16	+	27260156	CORL105	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.018818933302175544	[1051]	[1169,1267,1452,1128]	0	hSpCas9	negative selection	6498743
88810477	88810500	16	-	27260156	CORL105	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.1709649761717874	[304]	[393,249,363,271]	-3	hSpCas9	negative selection	6563025
88810091	88810114	16	-	27260156	CORL105	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.245325220316988	[234]	[277,145,310,208]	-4	hSpCas9	negative selection	6563026
88810541	88810564	16	-	27260156	CORL105	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7944606067007248	[671]	[442,435,490,449]	-8	hSpCas9	negative selection	6563027
88811547	88811570	16	+	27260156	HS294T	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.018681359099537054	[664]	[241,252,237,319]	0	hSpCas9	negative selection	6619992
88811549	88811572	16	-	27260156	HS294T	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.07869668475035951	[757]	[279,315,261,243]	-1	hSpCas9	negative selection	6619993
88810093	88810116	16	+	27260156	HS294T	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.24963441159025823	[1051]	[377,375,477,760]	3	hSpCas9	negative selection	6619994
88810477	88810500	16	-	27260156	HS294T	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.7632533235474181	[304]	[103,27,87,52]	-8	hSpCas9	negative selection	6684276
88810091	88810114	16	-	27260156	HS294T	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.4936458240064219	[234]	[53,98,38,65]	-6	hSpCas9	negative selection	6684277
88810541	88810564	16	-	27260156	HS294T	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.8585064973406545	[671]	[85,121,187,190]	-8	hSpCas9	negative selection	6684278
88811547	88811570	16	+	27260156	HCC44	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.48609406099437535	[664]	[689,342,844,365]	-6	hSpCas9	negative selection	6741243
88811549	88811572	16	-	27260156	HCC44	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.6319090810913807	[757]	[557,618,652,391]	-7	hSpCas9	negative selection	6741244
88810093	88810116	16	+	27260156	HCC44	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.30057141941387344	[1051]	[1353,836,860,843]	-5	hSpCas9	negative selection	6741245
88810477	88810500	16	-	27260156	HCC44	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.8484282978199047	[304]	[237,169,147,207]	-8	hSpCas9	negative selection	6805527
88810091	88810114	16	-	27260156	HCC44	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.6720594051138773	[234]	[230,74,164,211]	-7	hSpCas9	negative selection	6805528
88810541	88810564	16	-	27260156	HCC44	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.4351939379590866	[671]	[299,189,401,265]	-9	hSpCas9	negative selection	6805529
88811547	88811570	16	+	27260156	G402	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.25468663051321794	[664]	[759,518,887,558]	-3	hSpCas9	negative selection	6862494
88811549	88811572	16	-	27260156	G402	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.20347247319858913	[757]	[667,1218,767,570]	-3	hSpCas9	negative selection	6862495
88810093	88810116	16	+	27260156	G402	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.11078608537045875	[1051]	[1471,1120,1229,974]	-1	hSpCas9	negative selection	6862496
88810477	88810500	16	-	27260156	G402	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.3243791742727826	[304]	[340,232,184,424]	-4	hSpCas9	negative selection	6926778
88810091	88810114	16	-	27260156	G402	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.07119226745067198	[234]	[568,211,98,250]	-1	hSpCas9	negative selection	6926779
88810541	88810564	16	-	27260156	G402	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.8354343914780389	[671]	[218,223,258,214]	-9	hSpCas9	negative selection	6926780
88811547	88811570	16	+	27260156	L33	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.03208557711290899	[664]	[614,251,399,734]	0	hSpCas9	negative selection	6983745
88811549	88811572	16	-	27260156	L33	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.06542406029286507	[757]	[789,234,485,758]	-1	hSpCas9	negative selection	6983746
88810093	88810116	16	+	27260156	L33	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.11825838324143523	[1051]	[1158,461,696,1170]	2	hSpCas9	negative selection	6983747
88810477	88810500	16	-	27260156	L33	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.25595833637070076	[304]	[301,75,184,238]	-5	hSpCas9	negative selection	7048029
88810091	88810114	16	-	27260156	L33	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.5323964305910602	[234]	[187,79,98,108]	-8	hSpCas9	negative selection	7048030
88810541	88810564	16	-	27260156	L33	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.41032210682088643	[671]	[476,226,346,440]	-7	hSpCas9	negative selection	7048031
88811547	88811570	16	+	27260156	K562	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.726528238608885	[664]	[625,206,312,299]	-7	hSpCas9	negative selection	7104996
88811549	88811572	16	-	27260156	K562	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.13214286662634867	[757]	[860,553,745,340]	-2	hSpCas9	negative selection	7104997
88810093	88810116	16	+	27260156	K562	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.6133531277390416	[1051]	[727,687,518,526]	-6	hSpCas9	negative selection	7104998
88810477	88810500	16	-	27260156	K562	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.03969508211370243	[304]	[164,158,501,217]	0	hSpCas9	negative selection	7169280
88810091	88810114	16	-	27260156	K562	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-1.8375217788136933	[234]	[88,71,3,69]	-9	hSpCas9	negative selection	7169281
88810541	88810564	16	-	27260156	K562	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.249653435035131	[671]	[175,389,145,286]	-8	hSpCas9	negative selection	7169282
88811547	88811570	16	+	27260156	HT29	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.018850622917631454	[664]	[545,1007,819,808]	0	hSpCas9	negative selection	7226247
88811549	88811572	16	-	27260156	HT29	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.32298796523052525	[757]	[711,782,817,641]	-6	hSpCas9	negative selection	7226248
88810093	88810116	16	+	27260156	HT29	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.06146241733531288	[1051]	[1368,1209,1396,959]	-1	hSpCas9	negative selection	7226249
88810477	88810500	16	-	27260156	HT29	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.35590673735850753	[304]	[289,304,272,289]	-6	hSpCas9	negative selection	7290531
88810091	88810114	16	-	27260156	HT29	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.14370811919572268	[234]	[417,246,316,283]	2	hSpCas9	negative selection	7290532
88810541	88810564	16	-	27260156	HT29	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.9305872295262883	[671]	[443,383,482,400]	-8	hSpCas9	negative selection	7290533
88811547	88811570	16	+	27260156	MHHES1	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.04167005131523449	[664]	[827,756,786,712]	0	hSpCas9	negative selection	7347498
88811549	88811572	16	-	27260156	MHHES1	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.09944872083050804	[757]	[923,710,737,800]	-2	hSpCas9	negative selection	7347499
88810093	88810116	16	+	27260156	MHHES1	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.296482046554291	[1051]	[1484,1785,1649,1009]	5	hSpCas9	negative selection	7347500
88810477	88810500	16	-	27260156	MHHES1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.23915332210898493	[304]	[370,451,496,314]	4	hSpCas9	negative selection	7411782
88810091	88810114	16	-	27260156	MHHES1	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.014308272675097489	[234]	[332,480,171,136]	0	hSpCas9	negative selection	7411783
88810541	88810564	16	-	27260156	MHHES1	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.029448499495149	[671]	[389,453,347,307]	-9	hSpCas9	negative selection	7411784
88811547	88811570	16	+	27260156	MEWO	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.22756050485007623	[664]	[749,393,492]	-5	hSpCas9	negative selection	7468749
88811549	88811572	16	-	27260156	MEWO	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3330797716848291	[757]	[714,603,398]	-6	hSpCas9	negative selection	7468750
88810093	88810116	16	+	27260156	MEWO	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.009732836558853375	[1051]	[1027,1044,868]	0	hSpCas9	negative selection	7468751
88810477	88810500	16	-	27260156	MEWO	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.03998054079087632	[304]	[416,194,247]	-1	hSpCas9	negative selection	7533033
88810091	88810114	16	-	27260156	MEWO	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.28840541170220324	[234]	[128,207,192]	-6	hSpCas9	negative selection	7533034
88810541	88810564	16	-	27260156	MEWO	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.37745116314369925	[671]	[427,474,537]	-7	hSpCas9	negative selection	7533035
88811547	88811570	16	+	27260156	LNCAPCLONEFGC	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.23041269292634164	[664]	[474,547,600,440]	-4	hSpCas9	negative selection	7590000
88811549	88811572	16	-	27260156	LNCAPCLONEFGC	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.2918259929571814	[757]	[571,532,487,640]	-4	hSpCas9	negative selection	7590001
88810093	88810116	16	+	27260156	LNCAPCLONEFGC	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.07426307737726545	[1051]	[800,906,905,1007]	-1	hSpCas9	negative selection	7590002
88810477	88810500	16	-	27260156	LNCAPCLONEFGC	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.4066959051955903	[304]	[171,144,400,148]	-6	hSpCas9	negative selection	7654284
88810091	88810114	16	-	27260156	LNCAPCLONEFGC	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.18454821155725964	[234]	[204,194,144,196]	-3	hSpCas9	negative selection	7654285
88810541	88810564	16	-	27260156	LNCAPCLONEFGC	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.0038805348328055	[671]	[289,268,400,270]	-8	hSpCas9	negative selection	7654286
88811547	88811570	16	+	27260156	PANC0327	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.08909710930019404	[664]	[756,623,526,320]	-1	hSpCas9	negative selection	7711251
88811549	88811572	16	-	27260156	PANC0327	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.16571896892389415	[757]	[1142,542,651,741]	2	hSpCas9	negative selection	7711252
88810093	88810116	16	+	27260156	PANC0327	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.07624474853437913	[1051]	[1199,959,754,1045]	1	hSpCas9	negative selection	7711253
88810477	88810500	16	-	27260156	PANC0327	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.8362096851453353	[304]	[196,126,200,88]	-8	hSpCas9	negative selection	7775535
88810091	88810114	16	-	27260156	PANC0327	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.29546983141380756	[234]	[132,156,196,191]	-4	hSpCas9	negative selection	7775536
88810541	88810564	16	-	27260156	PANC0327	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.0010198153963006	[671]	[326,238,326,309]	-8	hSpCas9	negative selection	7775537
88811547	88811570	16	+	27260156	NCIH2009	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.043365035278467856	[664]	[1020,893,811]	0	hSpCas9	negative selection	7832502
88811549	88811572	16	-	27260156	NCIH2009	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.025586898951788672	[757]	[1051,1133,1039]	0	hSpCas9	negative selection	7832503
88810093	88810116	16	+	27260156	NCIH2009	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.1351352814147717	[1051]	[1452,1367,1213]	-2	hSpCas9	negative selection	7832504
88810477	88810500	16	-	27260156	NCIH2009	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.6468778349228297	[304]	[252,283,274]	-7	hSpCas9	negative selection	7896786
88810091	88810114	16	-	27260156	NCIH2009	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.10350297697181543	[234]	[394,192,347]	-1	hSpCas9	negative selection	7896787
88810541	88810564	16	-	27260156	NCIH2009	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6673835583130621	[671]	[971,578,296]	-7	hSpCas9	negative selection	7896788
88811547	88811570	16	+	27260156	NCIH1373	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.13003088317154876	[664]	[983,967,262,283]	1	hSpCas9	negative selection	7953753
88811549	88811572	16	-	27260156	NCIH1373	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.03772215535784429	[757]	[809,947,906,208]	0	hSpCas9	negative selection	7953754
88810093	88810116	16	+	27260156	NCIH1373	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.3423849300958539	[1051]	[2280,729,1856,338]	3	hSpCas9	negative selection	7953755
88810477	88810500	16	-	27260156	NCIH1373	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-1.086513717671693	[304]	[162,160,120,52]	-8	hSpCas9	negative selection	8018037
88810091	88810114	16	-	27260156	NCIH1373	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.18296784052837456	[234]	[224,388,72,58]	-2	hSpCas9	negative selection	8018038
88810541	88810564	16	-	27260156	NCIH1373	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.677826365515275	[671]	[211,205,298,57]	-9	hSpCas9	negative selection	8018039
88811547	88811570	16	+	27260156	PATU8902	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.2965771534180328	[664]	[1077,790,571,592]	-3	hSpCas9	negative selection	8075004
88811549	88811572	16	-	27260156	PATU8902	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.6926299814650105	[757]	[854,470,370,1024]	-6	hSpCas9	negative selection	8075005
88810093	88810116	16	+	27260156	PATU8902	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.12824524792824965	[1051]	[1531,1175,1211,1477]	-1	hSpCas9	negative selection	8075006
88810477	88810500	16	-	27260156	PATU8902	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.11589131660900653	[304]	[260,596,559,387]	1	hSpCas9	negative selection	8139288
88810091	88810114	16	-	27260156	PATU8902	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.08589868876081208	[234]	[96,135,743,303]	0	hSpCas9	negative selection	8139289
88810541	88810564	16	-	27260156	PATU8902	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.590323379685861	[671]	[371,515,166,210]	-8	hSpCas9	negative selection	8139290
88811547	88811570	16	+	27260156	PANC1	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.049354992768210315	[664]	[670,823,496,433]	0	hSpCas9	negative selection	8196255
88811549	88811572	16	-	27260156	PANC1	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.5269797190632581	[757]	[413,792,317,359]	-7	hSpCas9	negative selection	8196256
88810093	88810116	16	+	27260156	PANC1	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.34966516860697827	[1051]	[626,1097,607,591]	-5	hSpCas9	negative selection	8196257
88810477	88810500	16	-	27260156	PANC1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.5597108350090743	[304]	[137,289,221,95]	-7	hSpCas9	negative selection	8260539
88810091	88810114	16	-	27260156	PANC1	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.3089260431773162	[234]	[228,172,90,156]	-5	hSpCas9	negative selection	8260540
88810541	88810564	16	-	27260156	PANC1	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.4802427760837876	[671]	[419,537,422,309]	-6	hSpCas9	negative selection	8260541
88811547	88811570	16	+	27260156	PANC0813	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.367404867025402	[664]	[740,540,539,610]	-5	hSpCas9	negative selection	8317506
88811549	88811572	16	-	27260156	PANC0813	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.02622999888367239	[757]	[952,811,1049,698]	0	hSpCas9	negative selection	8317507
88810093	88810116	16	+	27260156	PANC0813	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.132977872083486	[1051]	[1205,1139,976,1185]	-2	hSpCas9	negative selection	8317508
88810477	88810500	16	-	27260156	PANC0813	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.6118628626177169	[304]	[384,122,170,269]	-7	hSpCas9	negative selection	8381790
88810091	88810114	16	-	27260156	PANC0813	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.12012467470981192	[234]	[306,277,282,157]	-2	hSpCas9	negative selection	8381791
88810541	88810564	16	-	27260156	PANC0813	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.0659566946003851	[671]	[284,301,486,422]	-8	hSpCas9	negative selection	8381792
88811547	88811570	16	+	27260156	RDES	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.11342809337182114	[664]	[698,732,922,994]	1	hSpCas9	negative selection	8438757
88811549	88811572	16	-	27260156	RDES	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.0021722012877916086	[757]	[636,876,1050,961]	0	hSpCas9	negative selection	8438758
88810093	88810116	16	+	27260156	RDES	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.12462268545913413	[1051]	[1148,1393,1166,1587]	2	hSpCas9	negative selection	8438759
88810477	88810500	16	-	27260156	RDES	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.062248975720463395	[304]	[301,374,311,347]	-1	hSpCas9	negative selection	8503041
88810091	88810114	16	-	27260156	RDES	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.08952147014742184	[234]	[250,178,316,273]	-1	hSpCas9	negative selection	8503042
88810541	88810564	16	-	27260156	RDES	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5788264267876134	[671]	[412,525,516,637]	-7	hSpCas9	negative selection	8503043
88811547	88811570	16	+	27260156	PC3	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.12888958340544543	[664]	[377,604,788,771]	-3	hSpCas9	negative selection	8560008
88811549	88811572	16	-	27260156	PC3	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.061327874638440805	[757]	[551,803,1120,551]	-1	hSpCas9	negative selection	8560009
88810093	88810116	16	+	27260156	PC3	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.18566831188193955	[1051]	[516,721,1852,1074]	-4	hSpCas9	negative selection	8560010
88810477	88810500	16	-	27260156	PC3	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.15252209559160512	[304]	[247,270,323,242]	-3	hSpCas9	negative selection	8624292
88810091	88810114	16	-	27260156	PC3	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.13404836333212877	[234]	[174,240,562,174]	3	hSpCas9	negative selection	8624293
88810541	88810564	16	-	27260156	PC3	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.38996780181441826	[671]	[328,532,835,499]	-7	hSpCas9	negative selection	8624294
88811547	88811570	16	+	27260156	PATU8988T	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.08140864525651792	[664]	[678,810,683,546]	1	hSpCas9	negative selection	8681259
88811549	88811572	16	-	27260156	PATU8988T	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.13601320203649947	[757]	[573,856,489,773]	-2	hSpCas9	negative selection	8681260
88810093	88810116	16	+	27260156	PATU8988T	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.1289059640025414	[1051]	[678,1140,815,1118]	-2	hSpCas9	negative selection	8681261
88810477	88810500	16	-	27260156	PATU8988T	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.5610708896303045	[304]	[206,264,114,220]	-7	hSpCas9	negative selection	8745543
88810091	88810114	16	-	27260156	PATU8988T	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.027717333025692903	[234]	[167,483,124,168]	0	hSpCas9	negative selection	8745544
88810541	88810564	16	-	27260156	PATU8988T	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.6218197051974015	[671]	[432,711,295,262]	-7	hSpCas9	negative selection	8745545
88811547	88811570	16	+	27260156	T47D	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.2197584646272006	[664]	[690,567,766,640]	-5	hSpCas9	negative selection	8802510
88811549	88811572	16	-	27260156	T47D	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3524710085423113	[757]	[733,687,601,745]	-6	hSpCas9	negative selection	8802511
88810093	88810116	16	+	27260156	T47D	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.09375023957044948	[1051]	[1281,976,1060,1294]	-2	hSpCas9	negative selection	8802512
88810477	88810500	16	-	27260156	T47D	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.1824047996167042	[304]	[286,275,326,366]	-4	hSpCas9	negative selection	8866794
88810091	88810114	16	-	27260156	T47D	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.14157784862497014	[234]	[244,240,219,288]	-3	hSpCas9	negative selection	8866795
88810541	88810564	16	-	27260156	T47D	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7458013381294148	[671]	[428,398,500,545]	-9	hSpCas9	negative selection	8866796
88811547	88811570	16	+	27260156	SU8686	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.11573626826940242	[664]	[497,437,792,765]	-2	hSpCas9	negative selection	8923761
88811549	88811572	16	-	27260156	SU8686	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.005967579356327635	[757]	[777,659,561,1037]	0	hSpCas9	negative selection	8923762
88810093	88810116	16	+	27260156	SU8686	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.04120956992329372	[1051]	[1026,1005,1041,1251]	0	hSpCas9	negative selection	8923763
88810477	88810500	16	-	27260156	SU8686	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.4770615856201099	[304]	[193,190,253,238]	-6	hSpCas9	negative selection	8988045
88810091	88810114	16	-	27260156	SU8686	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.08783448498609814	[234]	[204,229,236,200]	-1	hSpCas9	negative selection	8988046
88810541	88810564	16	-	27260156	SU8686	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.7498591205707876	[671]	[412,354,383,439]	-8	hSpCas9	negative selection	8988047
88811547	88811570	16	+	27260156	SKES1	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.24099123749015006	[664]	[668,597,573,432]	-5	hSpCas9	negative selection	9045012
88811549	88811572	16	-	27260156	SKES1	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3579020239183874	[757]	[741,709,542,415]	-7	hSpCas9	negative selection	9045013
88810093	88810116	16	+	27260156	SKES1	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.005402602422448055	[1051]	[1142,969,1165,937]	0	hSpCas9	negative selection	9045014
88810477	88810500	16	-	27260156	SKES1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.058733280292658785	[304]	[210,343,322,282]	-1	hSpCas9	negative selection	9109296
88810091	88810114	16	-	27260156	SKES1	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.1557700492603853	[234]	[247,262,212,135]	-3	hSpCas9	negative selection	9109297
88810541	88810564	16	-	27260156	SKES1	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.5580179813522639	[671]	[580,350,500,394]	-8	hSpCas9	negative selection	9109298
88811547	88811570	16	+	27260156	TOV112D	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.15520462091520748	[664]	[869,726,681,694]	3	hSpCas9	negative selection	9166263
88811549	88811572	16	-	27260156	TOV112D	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	0.04133485614001475	[757]	[970,689,812,646]	0	hSpCas9	negative selection	9166264
88810093	88810116	16	+	27260156	TOV112D	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	0.06697827731345174	[1051]	[1151,1143,883,1242]	1	hSpCas9	negative selection	9166265
88810477	88810500	16	-	27260156	TOV112D	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.07982792562939434	[304]	[267,279,254,346]	-1	hSpCas9	negative selection	9230547
88810091	88810114	16	-	27260156	TOV112D	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.07965470985134626	[234]	[108,548,199,199]	1	hSpCas9	negative selection	9230548
88810541	88810564	16	-	27260156	TOV112D	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.36858074194251034	[671]	[460,921,386,410]	-6	hSpCas9	negative selection	9230549
88811547	88811570	16	+	27260156	TC71	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	-0.20375920907796763	[664]	[542,572,514,864]	-5	hSpCas9	negative selection	9287514
88811549	88811572	16	-	27260156	TC71	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.11851291621299043	[757]	[716,844,680,753]	-3	hSpCas9	negative selection	9287515
88810093	88810116	16	+	27260156	TC71	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.18608131130034355	[1051]	[921,1085,958,1000]	-5	hSpCas9	negative selection	9287516
88810477	88810500	16	-	27260156	TC71	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.290156747346894	[304]	[239,301,263,263]	-7	hSpCas9	negative selection	9351798
88810091	88810114	16	-	27260156	TC71	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	-0.27707713373865883	[234]	[224,224,156,226]	-6	hSpCas9	negative selection	9351799
88810541	88810564	16	-	27260156	TC71	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.4046734326015893	[671]	[550,674,507,436]	-8	hSpCas9	negative selection	9351800
88811547	88811570	16	+	27260156	TC32	viability	CGCCTGCGATGTAGTCGATGCGG	APRT	ENSG00000198931	0.17757700575249835	[664]	[660,527,909,799]	3	hSpCas9	negative selection	9408765
88811549	88811572	16	-	27260156	TC32	viability	GGCCGCATCGACTACATCGCAGG	APRT	ENSG00000198931	-0.3489106752756025	[757]	[678,336,792,500]	-6	hSpCas9	negative selection	9408766
88810093	88810116	16	+	27260156	TC32	viability	ACGACGACCACCCTCTGTCCTGG	APRT	ENSG00000198931	-0.0032344194450513175	[1051]	[898,685,1360,1140]	0	hSpCas9	negative selection	9408767
88810477	88810500	16	-	27260156	TC32	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.10064254061813838	[304]	[217,267,337,244]	-2	hSpCas9	negative selection	9473049
88810091	88810114	16	-	27260156	TC32	viability	AGGACAGAGGGTGGTCGTCGTGG	APRT	ENSG00000198931	0.15389406562654495	[234]	[287,176,309,222]	3	hSpCas9	negative selection	9473050
88810541	88810564	16	-	27260156	TC32	viability	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-1.0853798174792084	[671]	[226,246,387,357]	-9	hSpCas9	negative selection	9473051
88809754	88809777	16	+	27869803	HPAFII	viability after 27 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.33257983401705987	[176]	[114,118,NaN]	2	hSpCas9	negative selection	9558903
88810130	88810153	16	+	27869803	HPAFII	viability after 27 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.11318225531397963	[195]	[129,95,NaN]	0	hSpCas9	negative selection	9558904
88810476	88810499	16	-	27869803	HPAFII	viability after 27 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.3978608171438365	[622]	[706,201,NaN]	3	hSpCas9	negative selection	9558905
88810541	88810564	16	-	27869803	HPAFII	viability after 27 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.1007437922879939	[663]	[462,210,NaN]	0	hSpCas9	negative selection	9558906
88811572	88811595	16	-	27869803	HPAFII	viability after 27 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.747579855317031	[80]	[14,33,NaN]	-5	hSpCas9	negative selection	9558907
88811580	88811603	16	+	27869803	HPAFII	viability after 27 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.4808999768148382	[152]	[49,63,NaN]	-4	hSpCas9	negative selection	9558908
88809754	88809777	16	+	27869803	HPAFII	viability after 15 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.18158562865791367	[176]	[303,82,NaN]	-2	hSpCas9	negative selection	9641352
88810130	88810153	16	+	27869803	HPAFII	viability after 15 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.24389514183513805	[195]	[373,171,NaN]	3	hSpCas9	negative selection	9641353
88810476	88810499	16	-	27869803	HPAFII	viability after 15 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.23414144639311196	[622]	[1175,545,NaN]	2	hSpCas9	negative selection	9641354
88810541	88810564	16	-	27869803	HPAFII	viability after 15 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.05370883367577295	[663]	[956,519,NaN]	0	hSpCas9	negative selection	9641355
88811572	88811595	16	-	27869803	HPAFII	viability after 15 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.3563614453884534	[80]	[33,33,NaN]	-8	hSpCas9	negative selection	9641356
88811580	88811603	16	+	27869803	HPAFII	viability after 15 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.08065692516743561	[152]	[255,92,NaN]	-1	hSpCas9	negative selection	9641357
88809754	88809777	16	+	27869803	ASPC1	viability after 36 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.004753453065827057	[547]	[140,315,123]	0	hSpCas9	negative selection	9723801
88810130	88810153	16	+	27869803	ASPC1	viability after 36 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	0.03741288864134429	[388]	[264,133,53]	0	hSpCas9	negative selection	9723802
88810476	88810499	16	-	27869803	ASPC1	viability after 36 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	-0.31667145202946967	[1531]	[630,308,378]	-3	hSpCas9	negative selection	9723803
88810541	88810564	16	-	27869803	ASPC1	viability after 36 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.2796933436407494	[1982]	[863,422,474]	-3	hSpCas9	negative selection	9723804
88811572	88811595	16	-	27869803	ASPC1	viability after 36 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.9183938611895366	[217]	[2,14,10]	-9	hSpCas9	negative selection	9723805
88811580	88811603	16	+	27869803	ASPC1	viability after 36 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.8113607298999932	[394]	[158,403,168]	7	hSpCas9	negative selection	9723806
88809754	88809777	16	+	27869803	PATU8988S	viability after 35 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.3306792962901862	[419]	[136,131,NaN]	-3	hSpCas9	negative selection	9806250
88810130	88810153	16	+	27869803	PATU8988S	viability after 35 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-1.516467072659446	[432]	[41,79,NaN]	-8	hSpCas9	negative selection	9806251
88810476	88810499	16	-	27869803	PATU8988S	viability after 35 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.3244329629167595	[1329]	[554,786,NaN]	3	hSpCas9	negative selection	9806252
88810541	88810564	16	-	27869803	PATU8988S	viability after 35 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	0.09268962179007367	[1450]	[696,548,NaN]	1	hSpCas9	negative selection	9806253
88811572	88811595	16	-	27869803	PATU8988S	viability after 35 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.6070226777822667	[192]	[65,35,NaN]	-6	hSpCas9	negative selection	9806254
88811580	88811603	16	+	27869803	PATU8988S	viability after 35 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.8490073558405778	[251]	[101,263,NaN]	8	hSpCas9	negative selection	9806255
88809754	88809777	16	+	27869803	PATU8988S	viability after 31 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.6817816234071032	[419]	[110,95,NaN]	-6	hSpCas9	negative selection	9888699
88810130	88810153	16	+	27869803	PATU8988S	viability after 31 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-1.4191853228746392	[432]	[64,63,NaN]	-8	hSpCas9	negative selection	9888700
88810476	88810499	16	-	27869803	PATU8988S	viability after 31 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.07486634466573405	[1329]	[441,706,NaN]	0	hSpCas9	negative selection	9888701
88810541	88810564	16	-	27869803	PATU8988S	viability after 31 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.04556935800160722	[1450]	[498,638,NaN]	0	hSpCas9	negative selection	9888702
88811572	88811595	16	-	27869803	PATU8988S	viability after 31 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.767681078260509	[192]	[53,33,NaN]	-7	hSpCas9	negative selection	9888703
88811580	88811603	16	+	27869803	PATU8988S	viability after 31 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	0.5651246671492359	[251]	[83,230,NaN]	6	hSpCas9	negative selection	9888704
88809754	88809777	16	+	27869803	HPAFII	viability after 35 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	-0.49732629937595557	[176]	[78,45,NaN]	-3	hSpCas9	negative selection	9971148
88810130	88810153	16	+	27869803	HPAFII	viability after 35 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.930537600785015	[195]	[52,50,NaN]	-5	hSpCas9	negative selection	9971149
88810476	88810499	16	-	27869803	HPAFII	viability after 35 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.3588339645111627	[622]	[490,306,NaN]	2	hSpCas9	negative selection	9971150
88810541	88810564	16	-	27869803	HPAFII	viability after 35 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.14876099190378111	[663]	[377,218,NaN]	-1	hSpCas9	negative selection	9971151
88811572	88811595	16	-	27869803	HPAFII	viability after 35 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.0020186420083435	[80]	[13,5,NaN]	-7	hSpCas9	negative selection	9971152
88811580	88811603	16	+	27869803	HPAFII	viability after 35 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.2108280910718665	[152]	[33,103,NaN]	-1	hSpCas9	negative selection	9971153
88809754	88809777	16	+	27869803	HPAFII	viability after 31 days	TAAGCGAGGTCAGCTCCACCAGG	APRT	ENSG00000198931	0.018559416892593217	[176]	[147,48,NaN]	0	hSpCas9	negative selection	10053597
88810130	88810153	16	+	27869803	HPAFII	viability after 31 days	TCTGAATCTCCAGCTCAGCCTGG	APRT	ENSG00000198931	-0.8056953575771408	[195]	[38,88,NaN]	-5	hSpCas9	negative selection	10053598
88810476	88810499	16	-	27869803	HPAFII	viability after 31 days	CTGCGTGCTCATCCGAAAGCGGG	APRT	ENSG00000198931	0.3679061041626872	[622]	[611,275,NaN]	2	hSpCas9	negative selection	10053599
88810541	88810564	16	-	27869803	HPAFII	viability after 31 days	CTGACAGGCCTAGACTCCCGAGG	APRT	ENSG00000198931	-0.289746299692313	[663]	[412,186,NaN]	-2	hSpCas9	negative selection	10053600
88811572	88811595	16	-	27869803	HPAFII	viability after 31 days	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.3500706288242408	[80]	[16,55,NaN]	-2	hSpCas9	negative selection	10053601
88811580	88811603	16	+	27869803	HPAFII	viability after 31 days	TCGCCTTCAGGTGTCGCGCCAGG	APRT	ENSG00000198931	-0.24652591531948087	[152]	[24,123,NaN]	-2	hSpCas9	negative selection	10053602
88810118	88810141	16	-	28162770	P31FUJ	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.4586836118307065	[68]	[58]	-4	hSpCas9	negative selection	10112409
88811572	88811595	16	-	28162770	P31FUJ	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.9983369507773558	[101]	[59]	-6	hSpCas9	negative selection	10112410
88811608	88811631	16	+	28162770	P31FUJ	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-0.5864391590290792	[22]	[17]	-5	hSpCas9	negative selection	10112411
88810438	88810461	16	+	28162770	P31FUJ	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.183892603933432	[144]	[74]	-7	hSpCas9	negative selection	10112412
88810069	88810092	16	-	28162770	P31FUJ	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.7652972852413995	[161]	[55]	-8	hSpCas9	negative selection	10112413
88810056	88810079	16	+	28162770	P31FUJ	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.17822223235784201	[269]	[358]	1	hSpCas9	negative selection	10112414
88811623	88811646	16	+	28162770	P31FUJ	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.1780592398199465	[180]	[93]	-7	hSpCas9	negative selection	10112415
88811590	88811613	16	+	28162770	P31FUJ	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.551160869288997	[301]	[519]	6	hSpCas9	negative selection	10112416
88810477	88810500	16	-	28162770	P31FUJ	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.4276463328036424	[452]	[715]	5	hSpCas9	negative selection	10112417
88811839	88811862	16	+	28162770	P31FUJ	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.07095132501298138	[218]	[244]	0	hSpCas9	negative selection	10112418
88810118	88810141	16	-	28162770	TF1	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10281775
88811572	88811595	16	-	28162770	TF1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10281776
88811608	88811631	16	+	28162770	TF1	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10281777
88810438	88810461	16	+	28162770	TF1	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10281778
88810069	88810092	16	-	28162770	TF1	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10281779
88810056	88810079	16	+	28162770	TF1	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10281780
88811623	88811646	16	+	28162770	TF1	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10281781
88811590	88811613	16	+	28162770	TF1	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10281782
88810477	88810500	16	-	28162770	TF1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	NaN	[NaN]	[563]	1	hSpCas9	negative selection	10281783
88811839	88811862	16	+	28162770	TF1	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10281784
88810118	88810141	16	-	28162770	SKM1	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.5868038475453237	[28]	[76]	5	hSpCas9	negative selection	10451141
88811572	88811595	16	-	28162770	SKM1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	1.076118687958781	[10]	[40]	8	hSpCas9	negative selection	10451142
88811608	88811631	16	+	28162770	SKM1	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-2.5000736031346436	[15]	[4]	-9	hSpCas9	negative selection	10451143
88810438	88810461	16	+	28162770	SKM1	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.2564045221677804	[49]	[36]	-7	hSpCas9	negative selection	10451144
88810069	88810092	16	-	28162770	SKM1	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.5396019673212805	[36]	[44]	-4	hSpCas9	negative selection	10451145
88810056	88810079	16	+	28162770	SKM1	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.06527284903436947	[57]	[97]	0	hSpCas9	negative selection	10451146
88811623	88811646	16	+	28162770	SKM1	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	0.1779983019779947	[23]	[47]	1	hSpCas9	negative selection	10451147
88811590	88811613	16	+	28162770	SKM1	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.9724141683281005	[63]	[221]	8	hSpCas9	negative selection	10451148
88810477	88810500	16	-	28162770	SKM1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10451149
88811839	88811862	16	+	28162770	SKM1	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.21534412620153032	[43]	[66]	-2	hSpCas9	negative selection	10451150
88810118	88810141	16	-	28162770	SKM1	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.5868038475453237	[28]	[76]	5	hSpCas9	negative selection	10620507
88811572	88811595	16	-	28162770	SKM1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	1.076118687958781	[10]	[40]	8	hSpCas9	negative selection	10620508
88811608	88811631	16	+	28162770	SKM1	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-2.5000736031346436	[15]	[4]	-9	hSpCas9	negative selection	10620509
88810438	88810461	16	+	28162770	SKM1	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.2564045221677804	[49]	[36]	-7	hSpCas9	negative selection	10620510
88810069	88810092	16	-	28162770	SKM1	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.5396019673212805	[36]	[44]	-4	hSpCas9	negative selection	10620511
88810056	88810079	16	+	28162770	SKM1	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.06527284903436947	[57]	[97]	0	hSpCas9	negative selection	10620512
88811623	88811646	16	+	28162770	SKM1	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	0.1779983019779947	[23]	[47]	1	hSpCas9	negative selection	10620513
88811590	88811613	16	+	28162770	SKM1	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.9724141683281005	[63]	[221]	8	hSpCas9	negative selection	10620514
88810477	88810500	16	-	28162770	SKM1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10620515
88811839	88811862	16	+	28162770	SKM1	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.21534412620153032	[43]	[66]	-2	hSpCas9	negative selection	10620516
88810118	88810141	16	-	28162770	PL21	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.5255399012834876	[82]	[51]	4	hSpCas9	negative selection	10789873
88811572	88811595	16	-	28162770	PL21	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	0.6816725255550709	[52]	[36]	6	hSpCas9	negative selection	10789874
88811608	88811631	16	+	28162770	PL21	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-4.157412390128764	[40]	[0]	-9	hSpCas9	negative selection	10789875
88810438	88810461	16	+	28162770	PL21	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-0.953106645806362	[128]	[28]	-6	hSpCas9	negative selection	10789876
88810069	88810092	16	-	28162770	PL21	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.9956474502649584	[196]	[42]	-6	hSpCas9	negative selection	10789877
88810056	88810079	16	+	28162770	PL21	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.7278349145376258	[196]	[141]	6	hSpCas9	negative selection	10789878
88811623	88811646	16	+	28162770	PL21	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-0.40131100902040506	[87]	[28]	-3	hSpCas9	negative selection	10789879
88811590	88811613	16	+	28162770	PL21	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	1.6467036193221076	[214]	[292]	9	hSpCas9	negative selection	10789880
88810477	88810500	16	-	28162770	PL21	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.27819003774060924	[364]	[130]	-2	hSpCas9	negative selection	10789881
88811839	88811862	16	+	28162770	PL21	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-1.0148732764815303	[129]	[27]	-6	hSpCas9	negative selection	10789882
88810118	88810141	16	-	28162770	P31FUJ	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.4586836118307065	[68]	[58]	-4	hSpCas9	negative selection	10959239
88811572	88811595	16	-	28162770	P31FUJ	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.9983369507773558	[101]	[59]	-6	hSpCas9	negative selection	10959240
88811608	88811631	16	+	28162770	P31FUJ	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-0.5864391590290792	[22]	[17]	-5	hSpCas9	negative selection	10959241
88810438	88810461	16	+	28162770	P31FUJ	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.183892603933432	[144]	[74]	-7	hSpCas9	negative selection	10959242
88810069	88810092	16	-	28162770	P31FUJ	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.7652972852413995	[161]	[55]	-8	hSpCas9	negative selection	10959243
88810056	88810079	16	+	28162770	P31FUJ	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.17822223235784201	[269]	[358]	1	hSpCas9	negative selection	10959244
88811623	88811646	16	+	28162770	P31FUJ	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.1780592398199465	[180]	[93]	-7	hSpCas9	negative selection	10959245
88811590	88811613	16	+	28162770	P31FUJ	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.551160869288997	[301]	[519]	6	hSpCas9	negative selection	10959246
88810477	88810500	16	-	28162770	P31FUJ	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.4276463328036424	[452]	[715]	5	hSpCas9	negative selection	10959247
88811839	88811862	16	+	28162770	P31FUJ	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.07095132501298138	[218]	[244]	0	hSpCas9	negative selection	10959248
88810118	88810141	16	-	28162770	OCIAML5	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.4491029638565678	[27]	[68]	4	hSpCas9	negative selection	11128605
88811572	88811595	16	-	28162770	OCIAML5	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	1.1479334291360033	[22]	[91]	8	hSpCas9	negative selection	11128606
88811608	88811631	16	+	28162770	OCIAML5	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-5.552506289005089	[25]	[0]	-9	hSpCas9	negative selection	11128607
88810438	88810461	16	+	28162770	OCIAML5	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.0016429269145068	[131]	[118]	-6	hSpCas9	negative selection	11128608
88810069	88810092	16	-	28162770	OCIAML5	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-2.0219915723063093	[116]	[51]	-8	hSpCas9	negative selection	11128609
88810056	88810079	16	+	28162770	OCIAML5	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.1751548978710275	[104]	[213]	1	hSpCas9	negative selection	11128610
88811623	88811646	16	+	28162770	OCIAML5	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-0.5576192123987418	[52]	[64]	-4	hSpCas9	negative selection	11128611
88811590	88811613	16	+	28162770	OCIAML5	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.4645082895291587	[107]	[268]	4	hSpCas9	negative selection	11128612
88810477	88810500	16	-	28162770	OCIAML5	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.9493308958972078	[207]	[724]	8	hSpCas9	negative selection	11128613
88811839	88811862	16	+	28162770	OCIAML5	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.220341924664053	[67]	[142]	1	hSpCas9	negative selection	11128614
88810118	88810141	16	-	28162770	EOL1	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-2.611505128669675	[173]	[14]	-9	hSpCas9	negative selection	11297971
88811572	88811595	16	-	28162770	EOL1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.6146110395374969	[92]	[15]	-7	hSpCas9	negative selection	11297972
88811608	88811631	16	+	28162770	EOL1	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-4.775891946570558	[51]	[0]	-9	hSpCas9	negative selection	11297973
88810438	88810461	16	+	28162770	EOL1	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-0.6047052965643341	[253]	[87]	-4	hSpCas9	negative selection	11297974
88810069	88810092	16	-	28162770	EOL1	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.1548100200427496	[354]	[83]	-6	hSpCas9	negative selection	11297975
88810056	88810079	16	+	28162770	EOL1	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.4342221449874537	[353]	[251]	4	hSpCas9	negative selection	11297976
88811623	88811646	16	+	28162770	EOL1	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-2.671303045293358	[132]	[10]	-9	hSpCas9	negative selection	11297977
88811590	88811613	16	+	28162770	EOL1	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.9879893871791261	[383]	[101]	-6	hSpCas9	negative selection	11297978
88810477	88810500	16	-	28162770	EOL1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.3578474772421065	[470]	[317]	3	hSpCas9	negative selection	11297979
88811839	88811862	16	+	28162770	EOL1	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-1.4539638516831954	[181]	[34]	-7	hSpCas9	negative selection	11297980
88810118	88810141	16	-	28162770	MOLM13	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.4166334010354851	[119]	[64]	-2	hSpCas9	negative selection	11467337
88811572	88811595	16	-	28162770	MOLM13	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.602499946346819	[104]	[24]	-7	hSpCas9	negative selection	11467338
88811608	88811631	16	+	28162770	MOLM13	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-5.43900121406394	[59]	[0]	-9	hSpCas9	negative selection	11467339
88810438	88810461	16	+	28162770	MOLM13	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.9915422370927187	[197]	[35]	-7	hSpCas9	negative selection	11467340
88810069	88810092	16	-	28162770	MOLM13	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	0.0176371896816771	[234]	[171]	0	hSpCas9	negative selection	11467341
88810056	88810079	16	+	28162770	MOLM13	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.10257354948146229	[296]	[199]	0	hSpCas9	negative selection	11467342
88811623	88811646	16	+	28162770	MOLM13	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.8958588890374104	[174]	[33]	-7	hSpCas9	negative selection	11467343
88811590	88811613	16	+	28162770	MOLM13	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.11707311917657748	[293]	[195]	0	hSpCas9	negative selection	11467344
88810477	88810500	16	-	28162770	MOLM13	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.45119062307185365	[623]	[329]	-3	hSpCas9	negative selection	11467345
88811839	88811862	16	+	28162770	MOLM13	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.3959964630627931	[143]	[136]	3	hSpCas9	negative selection	11467346
88810118	88810141	16	-	28162770	HEL	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.3743346813585844	[84]	[41]	-3	hSpCas9	negative selection	11636703
88811572	88811595	16	-	28162770	HEL	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.579653589336091	[76]	[32]	-4	hSpCas9	negative selection	11636704
88811608	88811631	16	+	28162770	HEL	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-2.589921924789918	[46]	[4]	-8	hSpCas9	negative selection	11636705
88810438	88810461	16	+	28162770	HEL	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.4748307643808192	[229]	[52]	-7	hSpCas9	negative selection	11636706
88810069	88810092	16	-	28162770	HEL	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.314192446107757	[263]	[67]	-6	hSpCas9	negative selection	11636707
88810056	88810079	16	+	28162770	HEL	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.4552062184116026	[258]	[120]	-3	hSpCas9	negative selection	11636708
88811623	88811646	16	+	28162770	HEL	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.5271861694419555	[170]	[37]	-7	hSpCas9	negative selection	11636709
88811590	88811613	16	+	28162770	HEL	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.01019526674509108	[261]	[168]	0	hSpCas9	negative selection	11636710
88810477	88810500	16	-	28162770	HEL	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.6716947263400812	[479]	[192]	-4	hSpCas9	negative selection	11636711
88811839	88811862	16	+	28162770	HEL	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-1.225157631992298	[145]	[39]	-6	hSpCas9	negative selection	11636712
88810118	88810141	16	-	28162770	MV411	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.04713890029694401	[53]	[46]	0	hSpCas9	negative selection	11806069
88811572	88811595	16	-	28162770	MV411	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-2.465280497136754	[58]	[8]	-8	hSpCas9	negative selection	11806070
88811608	88811631	16	+	28162770	MV411	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-5.2761244052742375	[45]	[0]	-9	hSpCas9	negative selection	11806071
88810438	88810461	16	+	28162770	MV411	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	0.1194299384067039	[105]	[96]	1	hSpCas9	negative selection	11806072
88810069	88810092	16	-	28162770	MV411	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.8663823487743867	[144]	[66]	-5	hSpCas9	negative selection	11806073
88810056	88810079	16	+	28162770	MV411	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.19057521382709897	[206]	[198]	1	hSpCas9	negative selection	11806074
88811623	88811646	16	+	28162770	MV411	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-1.4668079668833474	[104]	[31]	-7	hSpCas9	negative selection	11806075
88811590	88811613	16	+	28162770	MV411	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.4895280433834307	[204]	[122]	-4	hSpCas9	negative selection	11806076
88810477	88810500	16	-	28162770	MV411	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.4912723095924778	[352]	[417]	4	hSpCas9	negative selection	11806077
88811839	88811862	16	+	28162770	MV411	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.9682911402726617	[143]	[61]	-6	hSpCas9	negative selection	11806078
88810118	88810141	16	-	28162770	MONOMAC1	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.1424496192121134	[48]	[61]	1	hSpCas9	negative selection	11975435
88811572	88811595	16	-	28162770	MONOMAC1	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-1.7060504945474115	[36]	[12]	-8	hSpCas9	negative selection	11975436
88811608	88811631	16	+	28162770	MONOMAC1	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	1.8029631529404462	[28]	[115]	9	hSpCas9	negative selection	11975437
88810438	88810461	16	+	28162770	MONOMAC1	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.034765418160677	[83]	[46]	-7	hSpCas9	negative selection	11975438
88810069	88810092	16	-	28162770	MONOMAC1	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-1.4466507371310258	[106]	[44]	-8	hSpCas9	negative selection	11975439
88810056	88810079	16	+	28162770	MONOMAC1	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	-0.3490399405046037	[129]	[116]	-3	hSpCas9	negative selection	11975440
88811623	88811646	16	+	28162770	MONOMAC1	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-2.625880145863428	[69]	[12]	-9	hSpCas9	negative selection	11975441
88811590	88811613	16	+	28162770	MONOMAC1	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.9190520997597883	[159]	[96]	-6	hSpCas9	negative selection	11975442
88810477	88810500	16	-	28162770	MONOMAC1	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.46592816566287554	[239]	[379]	4	hSpCas9	negative selection	11975443
88811839	88811862	16	+	28162770	MONOMAC1	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.0038758468664428225	[86]	[99]	0	hSpCas9	negative selection	11975444
88810118	88810141	16	-	28162770	OCIAML2	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	-0.06853138167081563	[20]	[110]	0	hSpCas9	negative selection	12144801
88811572	88811595	16	-	28162770	OCIAML2	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.7825738315569013	[8]	[28]	-5	hSpCas9	negative selection	12144802
88811608	88811631	16	+	28162770	OCIAML2	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-4.277984747299765	[6]	[1]	-9	hSpCas9	negative selection	12144803
88810438	88810461	16	+	28162770	OCIAML2	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-2.4706298252421615	[40]	[40]	-8	hSpCas9	negative selection	12144804
88810069	88810092	16	-	28162770	OCIAML2	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-2.470629825242161	[33]	[33]	-8	hSpCas9	negative selection	12144805
88810056	88810079	16	+	28162770	OCIAML2	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.539354263330461	[35]	[289]	5	hSpCas9	negative selection	12144806
88811623	88811646	16	+	28162770	OCIAML2	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-0.39427893911204637	[22]	[96]	-3	hSpCas9	negative selection	12144807
88811590	88811613	16	+	28162770	OCIAML2	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	-0.2546924260430128	[47]	[222]	-2	hSpCas9	negative selection	12144808
88810477	88810500	16	-	28162770	OCIAML2	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	-0.7752433348273543	[87]	[284]	-5	hSpCas9	negative selection	12144809
88811839	88811862	16	+	28162770	OCIAML2	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	-0.2689959640725106	[19]	[91]	-2	hSpCas9	negative selection	12144810
88810118	88810141	16	-	28162770	OCIAML3	viability	GGAGATTCAGAAAGACGCCCTGG	APRT	ENSG00000198931	0.6337982771986492	[18]	[88]	6	hSpCas9	negative selection	12314167
88811572	88811595	16	-	28162770	OCIAML3	viability	GACACCTGAAGGCGACCCACGGG	APRT	ENSG00000198931	-0.14654866335294203	[21]	[59]	-1	hSpCas9	negative selection	12314168
88811608	88811631	16	+	28162770	OCIAML3	viability	GATGGCGGCGCGGAAGGAGGCGG	APRT	ENSG00000198931	-1.4684767582403042	[10]	[11]	-7	hSpCas9	negative selection	12314169
88810438	88810461	16	+	28162770	OCIAML3	viability	GGAATAGGAGGCCCACAGAGTGG	APRT	ENSG00000198931	-1.0589703649346895	[48]	[70]	-6	hSpCas9	negative selection	12314170
88810069	88810092	16	-	28162770	OCIAML3	viability	GATGATCTGCTGGCCACTGGTGG	APRT	ENSG00000198931	-0.7337324039907762	[64]	[117]	-5	hSpCas9	negative selection	12314171
88810056	88810079	16	+	28162770	OCIAML3	viability	GGGGAGACCCTTACCACCAGTGG	APRT	ENSG00000198931	0.6154457253047865	[39]	[184]	5	hSpCas9	negative selection	12314172
88811623	88811646	16	+	28162770	OCIAML3	viability	GGAGGCGGGGTCCTTCAGGACGG	APRT	ENSG00000198931	-0.5317233620698205	[33]	[70]	-4	hSpCas9	negative selection	12314173
88811590	88811613	16	+	28162770	OCIAML3	viability	GTGTCGCGCCAGGAGGCCGATGG	APRT	ENSG00000198931	0.11154500121058153	[64]	[211]	1	hSpCas9	negative selection	12314174
88810477	88810500	16	-	28162770	OCIAML3	viability	GCTGCGTGCTCATCCGAAAGCGG	APRT	ENSG00000198931	0.053690615744955594	[89]	[281]	0	hSpCas9	negative selection	12314175
88811839	88811862	16	+	28162770	OCIAML3	viability	TGGGGAAGTCGGGGAAGCTGCGG	APRT	ENSG00000198931	0.708555129696268	[44]	[221]	6	hSpCas9	negative selection	12314176