Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 367
• Symbol: AR
• Description: androgen receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/AR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67722926	67722949	X	-	26472758	Jiyoye	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.15956037646617194	[576]	[485]	1	hSpCas9	negative selection	8816
67711658	67711681	X	+	26472758	Jiyoye	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.6533359687752711	[42]	[50]	5	hSpCas9	negative selection	8817
67711430	67711453	X	+	26472758	Jiyoye	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.1396950706408875	[129]	[107]	1	hSpCas9	negative selection	8818
67686105	67686128	X	+	26472758	Jiyoye	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.721110685639705	[180]	[224]	5	hSpCas9	negative selection	8819
67717476	67717499	X	+	26472758	Jiyoye	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.18246909433117897	[207]	[177]	1	hSpCas9	negative selection	8820
67717533	67717556	X	+	26472758	Jiyoye	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	1.6989415058829835	[28]	[70]	8	hSpCas9	negative selection	8821
67721832	67721855	X	+	26472758	Jiyoye	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.29036171652312337	[89]	[82]	2	hSpCas9	negative selection	8822
67722813	67722836	X	+	26472758	Jiyoye	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.3652200650644948	[313]	[304]	2	hSpCas9	negative selection	8823
67643308	67643331	X	+	26472758	Jiyoye	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	-0.5470209288810018	[61]	[31]	-4	hSpCas9	negative selection	8824
67711457	67711480	X	+	26472758	Jiyoye	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	2.022834679449946	[30]	[94]	8	hSpCas9	negative selection	8825
67722926	67722949	X	-	26472758	KBM7	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.34022158419268944	[2198,1802]	[1518,885]	3	hSpCas9	negative selection	199934
67711658	67711681	X	+	26472758	KBM7	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.2650540870863036	[211,234]	[116,136]	2	hSpCas9	negative selection	199935
67711430	67711453	X	+	26472758	KBM7	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.36611089042605877	[425,357]	[177,288]	4	hSpCas9	negative selection	199936
67686105	67686128	X	+	26472758	KBM7	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.15659565338157788	[715,716]	[360,391]	1	hSpCas9	negative selection	199937
67717476	67717499	X	+	26472758	KBM7	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.2138758959534791	[1048,639]	[538,372]	2	hSpCas9	negative selection	199938
67717533	67717556	X	+	26472758	KBM7	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.4783278450211186	[258,169]	[105,166]	5	hSpCas9	negative selection	199939
67721832	67721855	X	+	26472758	KBM7	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	-0.32666070753059523	[516,605]	[302,132]	-3	hSpCas9	negative selection	199940
67722813	67722836	X	+	26472758	KBM7	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.4729758149764005	[1570,1499]	[1021,988]	5	hSpCas9	negative selection	199941
67643308	67643331	X	+	26472758	KBM7	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.7384648095698072	[129,88]	[71,95]	7	hSpCas9	negative selection	199942
67711457	67711480	X	+	26472758	KBM7	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	0.030788652596117058	[524,484]	[284,204]	0	hSpCas9	negative selection	199943
67722926	67722949	X	-	26472758	Raji	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.7087022070799773	[993]	[376]	6	hSpCas9	negative selection	391052
67711658	67711681	X	+	26472758	Raji	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.43669116062655944	[155]	[48]	4	hSpCas9	negative selection	391053
67711430	67711453	X	+	26472758	Raji	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.3143128393222429	[200]	[57]	3	hSpCas9	negative selection	391054
67686105	67686128	X	+	26472758	Raji	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.08414792225808798	[369]	[80]	0	hSpCas9	negative selection	391055
67717476	67717499	X	+	26472758	Raji	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.9438848030907201	[279]	[124]	8	hSpCas9	negative selection	391056
67717533	67717556	X	+	26472758	Raji	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	1.1073835353735992	[55]	[27]	8	hSpCas9	negative selection	391057
67721832	67721855	X	+	26472758	Raji	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.18492013584461986	[325]	[85]	1	hSpCas9	negative selection	391058
67722813	67722836	X	+	26472758	Raji	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.32242036930469253	[926]	[268]	3	hSpCas9	negative selection	391059
67643308	67643331	X	+	26472758	Raji	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.40994630539403065	[119]	[36]	4	hSpCas9	negative selection	391060
67711457	67711480	X	+	26472758	Raji	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.0032605283103929183	[297]	[68]	0	hSpCas9	negative selection	391061
67722926	67722949	X	-	26472758	K562	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	-0.08058143147373986	[1997]	[1594]	0	hSpCas9	negative selection	582170
67711658	67711681	X	+	26472758	K562	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.7045747726513226	[180]	[248]	6	hSpCas9	negative selection	582171
67711430	67711453	X	+	26472758	K562	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.7510707114660974	[346]	[492]	6	hSpCas9	negative selection	582172
67686105	67686128	X	+	26472758	K562	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-1.0429709485164367	[680]	[278]	-5	hSpCas9	negative selection	582173
67717476	67717499	X	+	26472758	K562	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.6933773877673971	[640]	[874]	6	hSpCas9	negative selection	582174
67717533	67717556	X	+	26472758	K562	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.2613918062701607	[168]	[170]	2	hSpCas9	negative selection	582175
67721832	67721855	X	+	26472758	K562	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	2.0026320555366923	[336]	[1139]	9	hSpCas9	negative selection	582176
67722813	67722836	X	+	26472758	K562	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.9084771053831471	[1318]	[2089]	7	hSpCas9	negative selection	582177
67643308	67643331	X	+	26472758	K562	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	-0.10040976933099421	[126]	[99]	0	hSpCas9	negative selection	582178
67711457	67711480	X	+	26472758	K562	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.39009959752894163	[384]	[247]	-3	hSpCas9	negative selection	582179
67545890	67545913	X	-	26627737	DLD1	viability	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	-0.32456256190478483	[723]	[153,246,148]	-3	hSpCas9	negative selection	846237
67569004	67569027	X	+	26627737	DLD1	viability	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.433270726645274	[725]	[190,183,134]	-4	hSpCas9	negative selection	846238
67686078	67686101	X	-	26627737	DLD1	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.916621995602487	[243]	[136,236,72]	8	hSpCas9	negative selection	846239
67694680	67694703	X	-	26627737	DLD1	viability	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.7828338112583918	[143]	[95,95,45]	7	hSpCas9	negative selection	846240
67711643	67711666	X	+	26627737	DLD1	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.24845037165391504	[1210]	[573,445,344]	2	hSpCas9	negative selection	846241
67717488	67717511	X	+	26627737	DLD1	viability	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.6929131527195129	[253]	[98,144,139]	7	hSpCas9	negative selection	846242
67545890	67545913	X	-	26627737	GBM cells	viability after 5 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	-0.4026224311704989	[280]	[103,123]	-6	hSpCas9	negative selection	928552
67569004	67569027	X	+	26627737	GBM cells	viability after 5 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.022476290417948068	[249]	[125,137]	0	hSpCas9	negative selection	928553
67686078	67686101	X	-	26627737	GBM cells	viability after 5 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.37581662974938906	[193]	[87,181]	6	hSpCas9	negative selection	928554
67694680	67694703	X	-	26627737	GBM cells	viability after 5 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	-0.8280676307078987	[143]	[43,42]	-8	hSpCas9	negative selection	928555
67711643	67711666	X	+	26627737	GBM cells	viability after 5 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.13299690702335032	[754]	[440,446]	2	hSpCas9	negative selection	928556
67717488	67717511	X	+	26627737	GBM cells	viability after 5 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.4092084204766465	[181]	[55,90]	-6	hSpCas9	negative selection	928557
67545890	67545913	X	-	26627737	GBM cells	viability after 13 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	-0.14379873986430952	[280]	[137,137]	-2	hSpCas9	negative selection	1010867
67569004	67569027	X	+	26627737	GBM cells	viability after 13 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.011405537973392865	[249]	[128,142]	0	hSpCas9	negative selection	1010868
67686078	67686101	X	-	26627737	GBM cells	viability after 13 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.17066494701767052	[193]	[107,126]	2	hSpCas9	negative selection	1010869
67694680	67694703	X	-	26627737	GBM cells	viability after 13 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	-1.26121707194894	[143]	[52,15]	-8	hSpCas9	negative selection	1010870
67711643	67711666	X	+	26627737	GBM cells	viability after 13 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.39573461236470275	[754]	[544,533]	5	hSpCas9	negative selection	1010871
67717488	67717511	X	+	26627737	GBM cells	viability after 13 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.08288723284381871	[181]	[79,103]	-1	hSpCas9	negative selection	1010872
67545890	67545913	X	-	26627737	GBM cells	viability after 21 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.1295112718687846	[280]	[166,166]	1	hSpCas9	negative selection	1093182
67569004	67569027	X	+	26627737	GBM cells	viability after 21 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.3304254632020304	[249]	[175,165]	3	hSpCas9	negative selection	1093183
67686078	67686101	X	-	26627737	GBM cells	viability after 21 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.15792839188247335	[193]	[138,97]	1	hSpCas9	negative selection	1093184
67694680	67694703	X	-	26627737	GBM cells	viability after 21 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.6096987912711136	[143]	[133,105]	6	hSpCas9	negative selection	1093185
67711643	67711666	X	+	26627737	GBM cells	viability after 21 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.2720269116747953	[754]	[511,479]	3	hSpCas9	negative selection	1093186
67717488	67717511	X	+	26627737	GBM cells	viability after 21 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.3703081099531686	[181]	[143,112]	4	hSpCas9	negative selection	1093187
67545890	67545913	X	-	26627737	RPE1	viability after 9 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.3074770848044082	[250]	[221,158]	7	hSpCas9	negative selection	1175497
67569004	67569027	X	+	26627737	RPE1	viability after 9 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.4974370879877972	[1264]	[328,217]	-4	hSpCas9	negative selection	1175498
67686078	67686101	X	-	26627737	RPE1	viability after 9 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.45218559225613864	[877]	[189,214]	-3	hSpCas9	negative selection	1175499
67694680	67694703	X	-	26627737	RPE1	viability after 9 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	1.8515768512814745	[113]	[61,214]	8	hSpCas9	negative selection	1175500
67711643	67711666	X	+	26627737	RPE1	viability after 9 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.4980646051502524	[2742]	[628,580]	-4	hSpCas9	negative selection	1175501
67717488	67717511	X	+	26627737	RPE1	viability after 9 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.4520665310457527	[541]	[201,270]	3	hSpCas9	negative selection	1175502
67545890	67545913	X	-	26627737	RPE1	viability after 12 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.148983049825434	[250]	[218,75]	7	hSpCas9	negative selection	1257812
67569004	67569027	X	+	26627737	RPE1	viability after 12 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.5540309051670647	[1264]	[247,213]	-4	hSpCas9	negative selection	1257813
67686078	67686101	X	-	26627737	RPE1	viability after 12 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.04528412453510462	[877]	[163,296]	0	hSpCas9	negative selection	1257814
67694680	67694703	X	-	26627737	RPE1	viability after 12 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	1.7821700816572472	[113]	[82,128]	8	hSpCas9	negative selection	1257815
67711643	67711666	X	+	26627737	RPE1	viability after 12 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.18246392077641382	[2742]	[730,562]	-1	hSpCas9	negative selection	1257816
67717488	67717511	X	+	26627737	RPE1	viability after 12 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.23926820505193686	[541]	[82,265]	1	hSpCas9	negative selection	1257817
67545890	67545913	X	-	26627737	RPE1	viability after 15 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.6711206643382894	[250]	[303,150]	8	hSpCas9	negative selection	1340127
67569004	67569027	X	+	26627737	RPE1	viability after 15 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-1.190694998349076	[1264]	[197,116]	-6	hSpCas9	negative selection	1340128
67686078	67686101	X	-	26627737	RPE1	viability after 15 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.013992399671829803	[877]	[318,184]	0	hSpCas9	negative selection	1340129
67694680	67694703	X	-	26627737	RPE1	viability after 15 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	2.3850567922247197	[113]	[142,192]	9	hSpCas9	negative selection	1340130
67711643	67711666	X	+	26627737	RPE1	viability after 15 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.24561545853047484	[2742]	[796,516]	-1	hSpCas9	negative selection	1340131
67717488	67717511	X	+	26627737	RPE1	viability after 15 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.04913277181399517	[541]	[94,219]	0	hSpCas9	negative selection	1340132
67545890	67545913	X	-	26627737	RPE1	viability after 18 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.4287342154908922	[250]	[250,108]	7	hSpCas9	negative selection	1422442
67569004	67569027	X	+	26627737	RPE1	viability after 18 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.74004885581583	[1264]	[244,160]	-4	hSpCas9	negative selection	1422443
67686078	67686101	X	-	26627737	RPE1	viability after 18 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.022095330086548792	[877]	[228,252]	0	hSpCas9	negative selection	1422444
67694680	67694703	X	-	26627737	RPE1	viability after 18 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	1.443468257875778	[113]	[44,124]	7	hSpCas9	negative selection	1422445
67711643	67711666	X	+	26627737	RPE1	viability after 18 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3983449080483308	[2742]	[565,556]	-3	hSpCas9	negative selection	1422446
67717488	67717511	X	+	26627737	RPE1	viability after 18 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.24526636141731062	[541]	[125,223]	1	hSpCas9	negative selection	1422447
67545890	67545913	X	-	26627737	HeLa	viability after 8 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.06441984332959305	[280]	[181,33,175]	0	hSpCas9	negative selection	1504757
67569004	67569027	X	+	26627737	HeLa	viability after 8 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.014400069180365583	[385]	[137,253,113]	0	hSpCas9	negative selection	1504758
67686078	67686101	X	-	26627737	HeLa	viability after 8 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.5888785120855954	[338]	[170,51,87]	-5	hSpCas9	negative selection	1504759
67694680	67694703	X	-	26627737	HeLa	viability after 8 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.41012342136517654	[131]	[86,3,135]	4	hSpCas9	negative selection	1504760
67711643	67711666	X	+	26627737	HeLa	viability after 8 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.9707087606913845	[666]	[644,654,432]	7	hSpCas9	negative selection	1504761
67717488	67717511	X	+	26627737	HeLa	viability after 8 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.272090162886384	[270]	[94,108,88]	-3	hSpCas9	negative selection	1504762
67545890	67545913	X	-	26627737	HeLa	viability after 12 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.6220725879430059	[280]	[189,126,224]	5	hSpCas9	negative selection	1587072
67569004	67569027	X	+	26627737	HeLa	viability after 12 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.5343504148944278	[385]	[181,48,107]	-5	hSpCas9	negative selection	1587073
67686078	67686101	X	-	26627737	HeLa	viability after 12 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.4897240166069373	[338]	[94,91,112]	-4	hSpCas9	negative selection	1587074
67694680	67694703	X	-	26627737	HeLa	viability after 12 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.8323955478194807	[131]	[106,131,48]	6	hSpCas9	negative selection	1587075
67711643	67711666	X	+	26627737	HeLa	viability after 12 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.5953276699014447	[666]	[436,349,469]	5	hSpCas9	negative selection	1587076
67717488	67717511	X	+	26627737	HeLa	viability after 12 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.868410286120212	[270]	[5,121,47]	-7	hSpCas9	negative selection	1587077
67545890	67545913	X	-	26627737	HeLa	viability after 15 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.23163017653388834	[280]	[68,185,149]	2	hSpCas9	negative selection	1669387
67569004	67569027	X	+	26627737	HeLa	viability after 15 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.16664157392573586	[385]	[113,109,200]	-1	hSpCas9	negative selection	1669388
67686078	67686101	X	-	26627737	HeLa	viability after 15 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.6901884049004585	[338]	[55,78,124]	-6	hSpCas9	negative selection	1669389
67694680	67694703	X	-	26627737	HeLa	viability after 15 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	1.1552349058990723	[131]	[50,103,211]	7	hSpCas9	negative selection	1669390
67711643	67711666	X	+	26627737	HeLa	viability after 15 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.8707336686203424	[666]	[452,457,585]	6	hSpCas9	negative selection	1669391
67717488	67717511	X	+	26627737	HeLa	viability after 15 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.6303855696966095	[270]	[147,273,83]	5	hSpCas9	negative selection	1669392
67545890	67545913	X	-	26627737	HeLa	viability after 18 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.24751719619564486	[280]	[45,157,149]	2	hSpCas9	negative selection	1751702
67569004	67569027	X	+	26627737	HeLa	viability after 18 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.2105135208515096	[385]	[69,88,200]	-2	hSpCas9	negative selection	1751703
67686078	67686101	X	-	26627737	HeLa	viability after 18 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.7226822456221126	[338]	[34,63,124]	-6	hSpCas9	negative selection	1751704
67694680	67694703	X	-	26627737	HeLa	viability after 18 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	1.1458402463259159	[131]	[35,81,211]	7	hSpCas9	negative selection	1751705
67711643	67711666	X	+	26627737	HeLa	viability after 18 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.8821351006495535	[666]	[306,384,585]	6	hSpCas9	negative selection	1751706
67717488	67717511	X	+	26627737	HeLa	viability after 18 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.6014053196588316	[270]	[94,223,83]	5	hSpCas9	negative selection	1751707
67545890	67545913	X	-	26627737	HCT116	viability after 6 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.493139598417259	[547]	[237,244]	7	hSpCas9	negative selection	1834017
67569004	67569027	X	+	26627737	HCT116	viability after 6 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.4194691703894168	[801]	[72,105]	-2	hSpCas9	negative selection	1834018
67686078	67686101	X	-	26627737	HCT116	viability after 6 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-1.5813594859825102	[271]	[12,14]	-7	hSpCas9	negative selection	1834019
67694680	67694703	X	-	26627737	HCT116	viability after 6 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	-0.3064679219158173	[168]	[54,2]	-2	hSpCas9	negative selection	1834020
67711643	67711666	X	+	26627737	HCT116	viability after 6 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.5564790105949751	[1961]	[354,507]	3	hSpCas9	negative selection	1834021
67717488	67717511	X	+	26627737	HCT116	viability after 6 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.5752215864802996	[549]	[126,19]	-3	hSpCas9	negative selection	1834022
67545890	67545913	X	-	26627737	HCT116	viability after 8 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.0969570230972958	[196]	[263,187,244]	8	hSpCas9	negative selection	1916332
67569004	67569027	X	+	26627737	HCT116	viability after 8 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.16195635827398458	[305]	[246,132,186]	1	hSpCas9	negative selection	1916333
67686078	67686101	X	-	26627737	HCT116	viability after 8 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	1.119105889701274	[104]	[91,123,159]	8	hSpCas9	negative selection	1916334
67694680	67694703	X	-	26627737	HCT116	viability after 8 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.27180210374179015	[97]	[81,57,55]	3	hSpCas9	negative selection	1916335
67711643	67711666	X	+	26627737	HCT116	viability after 8 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.01613632407279053	[884]	[451,580,413]	0	hSpCas9	negative selection	1916336
67717488	67717511	X	+	26627737	HCT116	viability after 8 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.3647388122348869	[266]	[78,136,125]	-4	hSpCas9	negative selection	1916337
67545890	67545913	X	-	26627737	HCT116	viability after 9 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.7010653830016367	[547]	[114,334]	5	hSpCas9	negative selection	1998647
67569004	67569027	X	+	26627737	HCT116	viability after 9 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-1.4436319945900529	[801]	[128,38]	-7	hSpCas9	negative selection	1998648
67686078	67686101	X	-	26627737	HCT116	viability after 9 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-1.2316347542897201	[271]	[64,3]	-7	hSpCas9	negative selection	1998649
67694680	67694703	X	-	26627737	HCT116	viability after 9 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.6450437517551764	[168]	[150,6]	5	hSpCas9	negative selection	1998650
67711643	67711666	X	+	26627737	HCT116	viability after 9 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.007555920293212504	[1961]	[657,412]	0	hSpCas9	negative selection	1998651
67717488	67717511	X	+	26627737	HCT116	viability after 9 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-3.4691519073516464	[549]	[5,18]	-9	hSpCas9	negative selection	1998652
67545890	67545913	X	-	26627737	HCT116	viability after 12 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.6692115770573422	[196]	[190,181,118]	6	hSpCas9	negative selection	2080962
67569004	67569027	X	+	26627737	HCT116	viability after 12 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.12877544481605466	[305]	[227,138,154]	1	hSpCas9	negative selection	2080963
67686078	67686101	X	-	26627737	HCT116	viability after 12 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.9962300305264576	[104]	[86,99,144]	8	hSpCas9	negative selection	2080964
67694680	67694703	X	-	26627737	HCT116	viability after 12 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.9233938659323967	[97]	[106,88,95]	7	hSpCas9	negative selection	2080965
67711643	67711666	X	+	26627737	HCT116	viability after 12 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.09262946399770877	[884]	[415,420,655]	1	hSpCas9	negative selection	2080966
67717488	67717511	X	+	26627737	HCT116	viability after 12 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.40937119227192587	[266]	[35,143,143]	-4	hSpCas9	negative selection	2080967
67545890	67545913	X	-	26627737	HCT116	viability after 15 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.2834748107171285	[196]	[323,222,284]	8	hSpCas9	negative selection	2163277
67569004	67569027	X	+	26627737	HCT116	viability after 15 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	-0.41246487389931413	[305]	[202,90,110]	-4	hSpCas9	negative selection	2163278
67686078	67686101	X	-	26627737	HCT116	viability after 15 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.8491318065842901	[104]	[90,62,168]	7	hSpCas9	negative selection	2163279
67694680	67694703	X	-	26627737	HCT116	viability after 15 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.6560582835730002	[97]	[113,54,99]	6	hSpCas9	negative selection	2163280
67711643	67711666	X	+	26627737	HCT116	viability after 15 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.17674732867280074	[884]	[419,530,394]	-2	hSpCas9	negative selection	2163281
67717488	67717511	X	+	26627737	HCT116	viability after 15 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.06531777446847643	[266]	[109,189,174]	0	hSpCas9	negative selection	2163282
67545890	67545913	X	-	26627737	HCT116	viability after 18 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.0541530586446626	[196]	[265,197,125]	7	hSpCas9	negative selection	2245592
67569004	67569027	X	+	26627737	HCT116	viability after 18 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.48987471235458135	[305]	[272,165,185]	4	hSpCas9	negative selection	2245593
67686078	67686101	X	-	26627737	HCT116	viability after 18 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5989728671360316	[104]	[39,71,120]	5	hSpCas9	negative selection	2245594
67694680	67694703	X	-	26627737	HCT116	viability after 18 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.9535116353862305	[97]	[208,2,67]	7	hSpCas9	negative selection	2245595
67711643	67711666	X	+	26627737	HCT116	viability after 18 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.45039505467301044	[884]	[707,395,665]	4	hSpCas9	negative selection	2245596
67717488	67717511	X	+	26627737	HCT116	viability after 18 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.6428820849369532	[266]	[26,96,124]	-5	hSpCas9	negative selection	2245597
67643249	67643272	X	+	24336569	HL60	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	1.0057952144814584	[416]	[1771]	7	hSpCas9	negative selection	2248338
67643284	67643307	X	-	24336569	HL60	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	1.757439657303529	[167]	[1201]	9	hSpCas9	negative selection	2248339
67643306	67643329	X	-	24336569	HL60	viability	ACAGATCAGGCAGGTCTTCTGGG	AR	ENSG00000169083	1.5337809670283025	[219]	[1347]	9	hSpCas9	negative selection	2248340
67643315	67643338	X	-	24336569	HL60	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	-0.6930617278535192	[737]	[965]	-6	hSpCas9	negative selection	2248341
67643323	67643346	X	+	24336569	HL60	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	0.7395657583257844	[479]	[1695]	6	hSpCas9	negative selection	2248342
67643335	67643358	X	+	24336569	HL60	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	-0.010683745484558665	[526]	[1106]	0	hSpCas9	negative selection	2248343
67643350	67643373	X	+	24336569	HL60	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	-0.7524581745010012	[487]	[612]	-6	hSpCas9	negative selection	2248344
67643361	67643384	X	+	24336569	HL60	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	0.6426611477638854	[552]	[1826]	5	hSpCas9	negative selection	2248345
67643399	67643422	X	-	24336569	HL60	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-1.0814641006288976	[0]	[0]	-7	hSpCas9	negative selection	2248346
67686006	67686029	X	-	24336569	HL60	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.268867709262132	[683]	[1743]	2	hSpCas9	negative selection	2248347
67643249	67643272	X	+	24336569	KBM7	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	0.9740555478366066	[449]	[2410]	8	hSpCas9	negative selection	2315515
67643284	67643307	X	-	24336569	KBM7	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.934291438794762	[263]	[1375]	7	hSpCas9	negative selection	2315516
67643306	67643329	X	-	24336569	KBM7	viability	ACAGATCAGGCAGGTCTTCTGGG	AR	ENSG00000169083	1.0638579578611445	[425]	[2428]	8	hSpCas9	negative selection	2315517
67643315	67643338	X	-	24336569	KBM7	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	0.11167204806944897	[584]	[1723]	1	hSpCas9	negative selection	2315518
67643323	67643346	X	+	24336569	KBM7	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	0.1893259359332758	[490]	[1526]	1	hSpCas9	negative selection	2315519
67643335	67643358	X	+	24336569	KBM7	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	-0.3262939396075132	[552]	[1202]	-3	hSpCas9	negative selection	2315520
67643350	67643373	X	+	24336569	KBM7	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	-0.0032955942322454024	[469]	[1278]	0	hSpCas9	negative selection	2315521
67643361	67643384	X	+	24336569	KBM7	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	0.8948130008981954	[321]	[1632]	7	hSpCas9	negative selection	2315522
67643399	67643422	X	-	24336569	KBM7	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-1.4475791965488813	[0]	[0]	-7	hSpCas9	negative selection	2315523
67686006	67686029	X	-	24336569	KBM7	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	1.0167295650849246	[348]	[1925]	8	hSpCas9	negative selection	2315524
67568700	67568723	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAATTAACAAGGCAGTAATTGG	AR	ENSG00000169083	0.1319348583869311	[497,98]	[128,8]	0	dCas9-VP64	positive selection	2388586
67568711	67568734	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGTAATTGGCATCAGGAGGG	AR	ENSG00000169083	2.1456622554353237	[41,8]	[42,4]	7	dCas9-VP64	positive selection	2388587
67568690	67568713	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGAATCTTGGCAATTAACAAGG	AR	ENSG00000169083	1.5771919268497123	[192,48]	[146,4]	6	dCas9-VP64	positive selection	2388588
67695792	67695815	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGAGTGTGTGTGTGTTGGGG	AR	ENSG00000169083	0.9390149814451021	[19,54]	[6,23]	4	dCas9-VP64	positive selection	2405161
67546512	67546535	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGCGGCGGCGGCGGCGGCGG	AR	ENSG00000169083	-1.372313513123184	[1,24]	[0,0]	-7	dCas9-VP64	positive selection	2468443
67568700	67568723	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAATTAACAAGGCAGTAATTGG	AR	ENSG00000169083	0.2678923639463332	[239,168]	[68,91]	2	dCas9-VP64	positive selection	2483841
67568711	67568734	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGTAATTGGCATCAGGAGGG	AR	ENSG00000169083	-1.870140977569866	[18,179]	[3,11]	-9	dCas9-VP64	positive selection	2483842
67568690	67568713	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGAATCTTGGCAATTAACAAGG	AR	ENSG00000169083	0.9214285138905755	[353,73]	[243,30]	6	dCas9-VP64	positive selection	2483843
67695792	67695815	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGAGTGTGTGTGTGTTGGGG	AR	ENSG00000169083	0.960334299848963	[58,78]	[13,70]	6	dCas9-VP64	positive selection	2500416
67546512	67546535	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGCGGCGGCGGCGGCGGCGG	AR	ENSG00000169083	1.0093040069059924	[1,1]	[0,0]	6	dCas9-VP64	positive selection	2563698
67643350	67643373	X	+	27260157	DLD1	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	-0.547972381795346	[]	[]	-4	hSpCas9	negative selection	2575026
67545227	67545250	X	-	27260157	DLD1	viability	GGATCACTTCGCGCACGCTCTGG	AR	ENSG00000169083	-0.851012571187051	[]	[]	-6	hSpCas9	negative selection	2575756
67545135	67545158	X	-	27260157	DLD1	viability	TGCACTTCCATCCTTGAGCTTGG	AR	ENSG00000169083	0.0407910134318948	[]	[]	0	hSpCas9	negative selection	2576771
67686006	67686029	X	-	27260157	DLD1	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.30624471059561	[]	[]	4	hSpCas9	negative selection	2577596
67643323	67643346	X	+	27260157	DLD1	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	1.25410778039843	[]	[]	9	hSpCas9	negative selection	2581775
67643335	67643358	X	+	27260157	DLD1	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	0.546119226310728	[]	[]	8	hSpCas9	negative selection	2604311
67545189	67545212	X	-	27260157	DLD1	viability	GCTCCTCGGTAGGTCTTGGACGG	AR	ENSG00000169083	0.168111749840664	[]	[]	3	hSpCas9	negative selection	2605607
67545659	67545682	X	-	27260157	DLD1	viability	CGGAGCAGCTGCTTAAGCCGGGG	AR	ENSG00000169083	0.575949747979798	[]	[]	8	hSpCas9	negative selection	2606926
67545594	67545617	X	-	27260157	DLD1	viability	TCATCCTCGTCCGGAGGTGCTGG	AR	ENSG00000169083	-1.22443684517826	[]	[]	-7	hSpCas9	negative selection	2609076
67545151	67545174	X	+	27260157	DLD1	viability	AAGTGCAGTTAGGGCTGGGAAGG	AR	ENSG00000169083	1.13150288147752	[]	[]	9	hSpCas9	negative selection	2611703
67643249	67643272	X	+	27260157	DLD1	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	1.28184823775375	[]	[]	9	hSpCas9	negative selection	2612231
67545524	67545547	X	-	27260157	DLD1	viability	CTGGGACGCAACCTCTCTCGGGG	AR	ENSG00000169083	0.334285268445206	[]	[]	4	hSpCas9	negative selection	2612971
67643399	67643422	X	-	27260157	DLD1	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-0.127220429596745	[]	[]	-1	hSpCas9	negative selection	2616730
67643361	67643384	X	+	27260157	DLD1	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	1.08675899310083	[]	[]	9	hSpCas9	negative selection	2618820
67545236	67545259	X	+	27260157	DLD1	viability	GCGCGAAGTGATCCAGAACCCGG	AR	ENSG00000169083	0.824271951469355	[]	[]	9	hSpCas9	negative selection	2619081
67643284	67643307	X	-	27260157	DLD1	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.0754869739150186	[]	[]	3	hSpCas9	negative selection	2621623
67545492	67545515	X	-	27260157	DLD1	viability	AGGGCCGACTGCGGCTGTGAAGG	AR	ENSG00000169083	0.0291778379871916	[]	[]	0	hSpCas9	negative selection	2644804
67643315	67643338	X	-	27260157	DLD1	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	-0.142255656302008	[]	[]	-1	hSpCas9	negative selection	2648084
67643350	67643373	X	+	27260157	HT1080	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	0.458298336372614	[]	[]	4	hSpCas9	negative selection	2651156
67545227	67545250	X	-	27260157	HT1080	viability	GGATCACTTCGCGCACGCTCTGG	AR	ENSG00000169083	-1.07366866575514	[]	[]	-8	hSpCas9	negative selection	2651886
67545135	67545158	X	-	27260157	HT1080	viability	TGCACTTCCATCCTTGAGCTTGG	AR	ENSG00000169083	1.29554508895868	[]	[]	9	hSpCas9	negative selection	2652901
67686006	67686029	X	-	27260157	HT1080	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.192823592257458	[]	[]	1	hSpCas9	negative selection	2653726
67643323	67643346	X	+	27260157	HT1080	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	0.745812059381036	[]	[]	6	hSpCas9	negative selection	2657905
67643335	67643358	X	+	27260157	HT1080	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	-0.120146708796878	[]	[]	0	hSpCas9	negative selection	2680441
67545189	67545212	X	-	27260157	HT1080	viability	GCTCCTCGGTAGGTCTTGGACGG	AR	ENSG00000169083	-0.260144347147588	[]	[]	0	hSpCas9	negative selection	2681737
67545659	67545682	X	-	27260157	HT1080	viability	CGGAGCAGCTGCTTAAGCCGGGG	AR	ENSG00000169083	0.270997892137239	[]	[]	2	hSpCas9	negative selection	2683056
67545594	67545617	X	-	27260157	HT1080	viability	TCATCCTCGTCCGGAGGTGCTGG	AR	ENSG00000169083	0.105914574180506	[]	[]	1	hSpCas9	negative selection	2685206
67545151	67545174	X	+	27260157	HT1080	viability	AAGTGCAGTTAGGGCTGGGAAGG	AR	ENSG00000169083	0.649257110841392	[]	[]	5	hSpCas9	negative selection	2687833
67643249	67643272	X	+	27260157	HT1080	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	1.44557041686731	[]	[]	9	hSpCas9	negative selection	2688361
67545524	67545547	X	-	27260157	HT1080	viability	CTGGGACGCAACCTCTCTCGGGG	AR	ENSG00000169083	0.160226720190318	[]	[]	1	hSpCas9	negative selection	2689101
67643399	67643422	X	-	27260157	HT1080	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.54421789295027	[]	[]	5	hSpCas9	negative selection	2692860
67643361	67643384	X	+	27260157	HT1080	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	1.54178766654858	[]	[]	9	hSpCas9	negative selection	2694950
67545236	67545259	X	+	27260157	HT1080	viability	GCGCGAAGTGATCCAGAACCCGG	AR	ENSG00000169083	0.946238153046707	[]	[]	7	hSpCas9	negative selection	2695211
67643284	67643307	X	-	27260157	HT1080	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.705661130445352	[]	[]	6	hSpCas9	negative selection	2697753
67545492	67545515	X	-	27260157	HT1080	viability	AGGGCCGACTGCGGCTGTGAAGG	AR	ENSG00000169083	0.52649334330357	[]	[]	4	hSpCas9	negative selection	2720934
67643315	67643338	X	-	27260157	HT1080	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	0.905912686103606	[]	[]	7	hSpCas9	negative selection	2724214
67643350	67643373	X	+	27260157	MKN45	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	-0.334006554707499	[]	[]	-1	hSpCas9	negative selection	2727286
67545227	67545250	X	-	27260157	MKN45	viability	GGATCACTTCGCGCACGCTCTGG	AR	ENSG00000169083	-1.0188550255599	[]	[]	-8	hSpCas9	negative selection	2728016
67545135	67545158	X	-	27260157	MKN45	viability	TGCACTTCCATCCTTGAGCTTGG	AR	ENSG00000169083	0.837416221758524	[]	[]	8	hSpCas9	negative selection	2729031
67686006	67686029	X	-	27260157	MKN45	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.429340282672106	[]	[]	6	hSpCas9	negative selection	2729856
67643323	67643346	X	+	27260157	MKN45	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	1.99763009021633	[]	[]	9	hSpCas9	negative selection	2734035
67643335	67643358	X	+	27260157	MKN45	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	0.839446402072107	[]	[]	8	hSpCas9	negative selection	2756571
67545189	67545212	X	-	27260157	MKN45	viability	GCTCCTCGGTAGGTCTTGGACGG	AR	ENSG00000169083	0.447077865546507	[]	[]	6	hSpCas9	negative selection	2757867
67545659	67545682	X	-	27260157	MKN45	viability	CGGAGCAGCTGCTTAAGCCGGGG	AR	ENSG00000169083	-0.0296978399627522	[]	[]	0	hSpCas9	negative selection	2759186
67545594	67545617	X	-	27260157	MKN45	viability	TCATCCTCGTCCGGAGGTGCTGG	AR	ENSG00000169083	-0.700301848059984	[]	[]	-7	hSpCas9	negative selection	2761336
67545151	67545174	X	+	27260157	MKN45	viability	AAGTGCAGTTAGGGCTGGGAAGG	AR	ENSG00000169083	1.08425948565594	[]	[]	8	hSpCas9	negative selection	2763963
67643249	67643272	X	+	27260157	MKN45	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	0.824716360899709	[]	[]	8	hSpCas9	negative selection	2764491
67545524	67545547	X	-	27260157	MKN45	viability	CTGGGACGCAACCTCTCTCGGGG	AR	ENSG00000169083	-0.365072304383539	[]	[]	-1	hSpCas9	negative selection	2765231
67643399	67643422	X	-	27260157	MKN45	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.443435145649394	[]	[]	6	hSpCas9	negative selection	2768990
67643361	67643384	X	+	27260157	MKN45	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	0.592326749984704	[]	[]	7	hSpCas9	negative selection	2771080
67545236	67545259	X	+	27260157	MKN45	viability	GCGCGAAGTGATCCAGAACCCGG	AR	ENSG00000169083	1.40691963991253	[]	[]	9	hSpCas9	negative selection	2771341
67643284	67643307	X	-	27260157	MKN45	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	-1.30438788309398	[]	[]	-8	hSpCas9	negative selection	2773883
67545492	67545515	X	-	27260157	MKN45	viability	AGGGCCGACTGCGGCTGTGAAGG	AR	ENSG00000169083	0.440986095231577	[]	[]	6	hSpCas9	negative selection	2797064
67643315	67643338	X	-	27260157	MKN45	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	0.10414872856106	[]	[]	0	hSpCas9	negative selection	2800344
67643350	67643373	X	+	27260157	RKO	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	0.442600938402675	[]	[]	2	hSpCas9	negative selection	2803416
67545227	67545250	X	-	27260157	RKO	viability	GGATCACTTCGCGCACGCTCTGG	AR	ENSG00000169083	-0.979846539201326	[]	[]	-8	hSpCas9	negative selection	2804146
67545135	67545158	X	-	27260157	RKO	viability	TGCACTTCCATCCTTGAGCTTGG	AR	ENSG00000169083	1.27440210747574	[]	[]	9	hSpCas9	negative selection	2805161
67686006	67686029	X	-	27260157	RKO	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.208603980199704	[]	[]	1	hSpCas9	negative selection	2805986
67643323	67643346	X	+	27260157	RKO	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	0.845604226869562	[]	[]	8	hSpCas9	negative selection	2810165
67643335	67643358	X	+	27260157	RKO	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	0.626227325393352	[]	[]	3	hSpCas9	negative selection	2832701
67545189	67545212	X	-	27260157	RKO	viability	GCTCCTCGGTAGGTCTTGGACGG	AR	ENSG00000169083	0.025908694129847	[]	[]	0	hSpCas9	negative selection	2833997
67545659	67545682	X	-	27260157	RKO	viability	CGGAGCAGCTGCTTAAGCCGGGG	AR	ENSG00000169083	0.677942608627989	[]	[]	7	hSpCas9	negative selection	2835316
67545594	67545617	X	-	27260157	RKO	viability	TCATCCTCGTCCGGAGGTGCTGG	AR	ENSG00000169083	-0.433776241787967	[]	[]	-6	hSpCas9	negative selection	2837466
67545151	67545174	X	+	27260157	RKO	viability	AAGTGCAGTTAGGGCTGGGAAGG	AR	ENSG00000169083	0.773213889535965	[]	[]	8	hSpCas9	negative selection	2840093
67643249	67643272	X	+	27260157	RKO	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	1.51100548812979	[]	[]	9	hSpCas9	negative selection	2840621
67545524	67545547	X	-	27260157	RKO	viability	CTGGGACGCAACCTCTCTCGGGG	AR	ENSG00000169083	0.350989997624099	[]	[]	1	hSpCas9	negative selection	2841361
67643399	67643422	X	-	27260157	RKO	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.462189794432454	[]	[]	2	hSpCas9	negative selection	2845120
67643361	67643384	X	+	27260157	RKO	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	0.730793597431692	[]	[]	8	hSpCas9	negative selection	2847210
67545236	67545259	X	+	27260157	RKO	viability	GCGCGAAGTGATCCAGAACCCGG	AR	ENSG00000169083	1.21078828752676	[]	[]	9	hSpCas9	negative selection	2847471
67643284	67643307	X	-	27260157	RKO	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	-0.671864453681732	[]	[]	-7	hSpCas9	negative selection	2850013
67545492	67545515	X	-	27260157	RKO	viability	AGGGCCGACTGCGGCTGTGAAGG	AR	ENSG00000169083	1.01937423651105	[]	[]	9	hSpCas9	negative selection	2873194
67643315	67643338	X	-	27260157	RKO	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	0.0802791844845994	[]	[]	0	hSpCas9	negative selection	2876474
67643350	67643373	X	+	27260157	SF268	viability	CACTATGGAGCTCTCACATGTGG	AR	ENSG00000169083	-0.0617110532867959	[]	[]	0	hSpCas9	negative selection	2879546
67545227	67545250	X	-	27260157	SF268	viability	GGATCACTTCGCGCACGCTCTGG	AR	ENSG00000169083	-0.647418650049434	[]	[]	-5	hSpCas9	negative selection	2880276
67545135	67545158	X	-	27260157	SF268	viability	TGCACTTCCATCCTTGAGCTTGG	AR	ENSG00000169083	0.628779204537083	[]	[]	8	hSpCas9	negative selection	2881291
67686006	67686029	X	-	27260157	SF268	viability	CACAGGTACTTCTGTTTCCCTGG	AR	ENSG00000169083	0.483986836662256	[]	[]	7	hSpCas9	negative selection	2882116
67643323	67643346	X	+	27260157	SF268	viability	ATCTGTGGAGATGAAGCTTCTGG	AR	ENSG00000169083	1.26656796284111	[]	[]	9	hSpCas9	negative selection	2886295
67643335	67643358	X	+	27260157	SF268	viability	GAAGCTTCTGGGTGTCACTATGG	AR	ENSG00000169083	-0.400650188155939	[]	[]	-3	hSpCas9	negative selection	2908831
67545189	67545212	X	-	27260157	SF268	viability	GCTCCTCGGTAGGTCTTGGACGG	AR	ENSG00000169083	1.1801203662741	[]	[]	9	hSpCas9	negative selection	2910127
67545659	67545682	X	-	27260157	SF268	viability	CGGAGCAGCTGCTTAAGCCGGGG	AR	ENSG00000169083	0.58520157826021	[]	[]	8	hSpCas9	negative selection	2911446
67545594	67545617	X	-	27260157	SF268	viability	TCATCCTCGTCCGGAGGTGCTGG	AR	ENSG00000169083	0.657328780545405	[]	[]	8	hSpCas9	negative selection	2913596
67545151	67545174	X	+	27260157	SF268	viability	AAGTGCAGTTAGGGCTGGGAAGG	AR	ENSG00000169083	1.15603951811918	[]	[]	9	hSpCas9	negative selection	2916223
67643249	67643272	X	+	27260157	SF268	viability	TTTCCAGTTTGGAGACTGCCAGG	AR	ENSG00000169083	1.11088434732954	[]	[]	9	hSpCas9	negative selection	2916751
67545524	67545547	X	-	27260157	SF268	viability	CTGGGACGCAACCTCTCTCGGGG	AR	ENSG00000169083	0.24703287524006	[]	[]	3	hSpCas9	negative selection	2917491
67643399	67643422	X	-	27260157	SF268	viability	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.893752701647802	[]	[]	9	hSpCas9	negative selection	2921250
67643361	67643384	X	+	27260157	SF268	viability	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	0.639101616958577	[]	[]	8	hSpCas9	negative selection	2923340
67545236	67545259	X	+	27260157	SF268	viability	GCGCGAAGTGATCCAGAACCCGG	AR	ENSG00000169083	0.885127815905283	[]	[]	9	hSpCas9	negative selection	2923601
67643284	67643307	X	-	27260157	SF268	viability	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	-0.448294689304305	[]	[]	-4	hSpCas9	negative selection	2926143
67545492	67545515	X	-	27260157	SF268	viability	AGGGCCGACTGCGGCTGTGAAGG	AR	ENSG00000169083	0.804044272037963	[]	[]	8	hSpCas9	negative selection	2949324
67643315	67643338	X	-	27260157	SF268	viability	TTCATCTCCACAGATCAGGCAGG	AR	ENSG00000169083	-0.138025643590006	[]	[]	-1	hSpCas9	negative selection	2952604
67643399	67643422	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-0.042395028251259806	[3,2]	[3,1]	0	hSpCas9	positive selection	2971132
67686047	67686070	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.0076456284552903	[3,3]	[3,2]	0	hSpCas9	positive selection	2971133
67711653	67711676	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-0.43629933284697475	[2,2]	[1,0]	-6	hSpCas9	positive selection	2971134
67711422	67711445	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	0.6894918200743221	[3,3]	[4,6]	9	hSpCas9	positive selection	2971135
67643399	67643422	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.32518505891242006	[3,3]	[3,2]	6	hSpCas9	positive selection	3038990
67686047	67686070	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.016449379120781926	[3,3]	[3,1]	0	hSpCas9	positive selection	3038991
67711653	67711676	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-0.44885218498047896	[2,2]	[1,0]	-6	hSpCas9	positive selection	3038992
67711422	67711445	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	0.18371576797630437	[3,3]	[2,3]	3	hSpCas9	positive selection	3038993
67643319	67643342		-	24336571	A375	resistance to PLX after 7 days	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.27006852404970194	[21,25]	[16,21]	-7	hSpCas9	positive selection	3125199
67686078	67686101		-	24336571	A375	resistance to PLX after 7 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.033304250265477786	[6,6]	[6,5]	-1	hSpCas9	positive selection	3125204
67686046	67686069		+	24336571	A375	resistance to PLX after 7 days	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.2379137020474692	[8,10]	[9,12]	7	hSpCas9	positive selection	3125215
67643285	67643308		-	24336571	A375	resistance to PLX after 7 days	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	-0.19789480384509828	[9,13]	[9,9]	-6	hSpCas9	positive selection	3125223
67643319	67643342		-	24336571	A375	resistance to PLX after 14 days	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.7418552159909553	[27,19]	[5,5]	-8	hSpCas9	positive selection	3182992
67686078	67686101		-	24336571	A375	resistance to PLX after 14 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.47731792928853156	[10,9]	[2,2]	-5	hSpCas9	positive selection	3182997
67686046	67686069		+	24336571	A375	resistance to PLX after 14 days	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	1.214079813024215	[5,10]	[4,12]	8	hSpCas9	positive selection	3183008
67643285	67643308		-	24336571	A375	resistance to PLX after 14 days	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	0.6994288005969136	[10,7]	[5,6]	6	hSpCas9	positive selection	3183016
67643319	67643342		-	24336571	A375	viability after 7 days	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.12566845952349326	[22]	[21,25]	2	hSpCas9	negative selection	3240785
67686078	67686101		-	24336571	A375	viability after 7 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.7105702252689168	[11]	[6,6]	-8	hSpCas9	negative selection	3240790
67686046	67686069		+	24336571	A375	viability after 7 days	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.8983420555533664	[19]	[8,10]	-8	hSpCas9	negative selection	3240801
67643285	67643308		-	24336571	A375	viability after 7 days	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	0.17861353079797626	[10]	[9,13]	2	hSpCas9	negative selection	3240809
67643319	67643342		-	24336571	A375	viability after 14 days	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.1499705692023826	[22]	[27,19]	2	hSpCas9	negative selection	3298578
67686078	67686101		-	24336571	A375	viability after 14 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.1512207825282327	[11]	[10,9]	-2	hSpCas9	negative selection	3298583
67686046	67686069		+	24336571	A375	viability after 14 days	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-1.0786153855157643	[19]	[5,10]	-8	hSpCas9	negative selection	3298594
67643285	67643308		-	24336571	A375	viability after 14 days	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	-0.13294319791897435	[10]	[10,7]	-1	hSpCas9	negative selection	3298602
67686078	67686101	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	1.3872032910821182	[56,59]	[0,0]	6	hSpCas9	positive selection	3337162
67711563	67711586	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	8.110879815191556	[210,237]	[809,0]	9	hSpCas9	positive selection	3337163
67686046	67686069	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	1.8824003915523604	[40,41]	[0,0]	7	hSpCas9	positive selection	3337164
67643386	67643409	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.10757909194115295	[141,141]	[0,0]	0	hSpCas9	positive selection	3356408
67711643	67711666	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3356409
67643319	67643342	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3356410
67643399	67643422	X	-	26780180	HT29	viability (Avana library 4 designs)	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-0.375450476504447	[]	[]	-6	hSpCas9	negative selection	3407244
67686046	67686069	X	+	26780180	HT29	viability (Avana library 4 designs)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	1.98067961988025	[]	[]	7	hSpCas9	negative selection	3407245
67711652	67711675	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-0.180819486992625	[]	[]	-3	hSpCas9	negative selection	3407246
67711421	67711444	X	+	26780180	HT29	viability (Avana library 4 designs)	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	0.260066753598884	[]	[]	0	hSpCas9	negative selection	3407247
67711421	67711444	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	-4.04283226792823	[]	[]	-4	hSpCas9	negative selection	3480194
67643399	67643422	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	2.64029603053414	[]	[]	4	hSpCas9	negative selection	3480195
67686046	67686069	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-6.2604072815976	[]	[]	-6	hSpCas9	negative selection	3480196
67711652	67711675	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-7.77564941924422	[]	[]	-7	hSpCas9	negative selection	3480197
67643361	67643384	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	-8.30191547327219	[]	[]	-7	hSpCas9	negative selection	3480198
67643284	67643307	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.365478999059505	[]	[]	0	hSpCas9	negative selection	3480199
67711421	67711444	X	+	26780180	A375	viability (Avana lentiGuide)	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	0.534656171210953	[]	[]	0	hSpCas9	negative selection	3588853
67643399	67643422	X	-	26780180	A375	viability (Avana lentiGuide)	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-5.49616048245977	[]	[]	-8	hSpCas9	negative selection	3588854
67686046	67686069	X	+	26780180	A375	viability (Avana lentiGuide)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-4.14984743466256	[]	[]	-7	hSpCas9	negative selection	3588855
67711652	67711675	X	+	26780180	A375	viability (Avana lentiGuide)	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-4.30889380749225	[]	[]	-7	hSpCas9	negative selection	3588856
67643361	67643384	X	+	26780180	A375	viability (Avana lentiGuide)	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	6.46143511170516	[]	[]	5	hSpCas9	negative selection	3588857
67643284	67643307	X	-	26780180	A375	viability (Avana lentiGuide)	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.334481347611675	[]	[]	0	hSpCas9	negative selection	3588858
67711421	67711444	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	-0.6274847366433944	[5]	[3,2]	-7	hSpCas9	positive selection	3697512
67643399	67643422	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	0.05118755227035961	[4]	[5,3]	1	hSpCas9	positive selection	3697513
67686046	67686069	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.6648507847665317	[5]	[3,2]	-7	hSpCas9	positive selection	3697514
67711652	67711675	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	-0.7327449200863954	[4]	[1,2]	-8	hSpCas9	positive selection	3697515
67643361	67643384	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	-0.406142374999263	[0]	[0,0]	-6	hSpCas9	positive selection	3697516
67643284	67643307	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	-0.06748602112837077	[6]	[5,5]	-1	hSpCas9	positive selection	3697517
67711421	67711444	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTAATCTGAAACTACAGGAGG	AR	ENSG00000169083	0.30161313489574754	[5]	[6,5]	8	hSpCas9	positive selection	3806119
67643399	67643422	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGACCCTTTACCTTCAGCGG	AR	ENSG00000169083	-0.2545522394040122	[4]	[5,1]	-3	hSpCas9	positive selection	3806120
67686046	67686069	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.19318926572948522	[4]	[4,4]	5	hSpCas9	positive selection	3806121
67711652	67711675	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGTACACGTGGTCAAGTGGG	AR	ENSG00000169083	0.136755006878797	[3]	[2,4]	3	hSpCas9	positive selection	3806122
67643361	67643384	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCACATGTGGAAGCTGCAAGG	AR	ENSG00000169083	-0.47854437827596563	[3]	[0,2]	-6	hSpCas9	positive selection	3806123
67643284	67643307	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGAAAGTAATAGTCAATGGG	AR	ENSG00000169083	0.23956404459590752	[5]	[5,5]	6	hSpCas9	positive selection	3806124
67643319	67643342	X	-	26780180	A375	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	1.42994163371055	[]	[]	8	hSpCas9	negative selection	3914380
67711643	67711666	X	+	26780180	A375	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	1.02215224015883	[]	[]	5	hSpCas9	negative selection	3914381
67686078	67686101	X	-	26780180	A375	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.53761914434198	[]	[]	1	hSpCas9	negative selection	3914382
67686046	67686069	X	+	26780180	A375	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.932410558463437	[]	[]	4	hSpCas9	negative selection	3914383
67711563	67711586	X	-	26780180	A375	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.464372064694391	[]	[]	1	hSpCas9	negative selection	3914384
67643386	67643409	X	+	26780180	A375	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.692043431707708	[]	[]	2	hSpCas9	negative selection	3914385
67643319	67643342	X	-	26780180	HT29	viability (GeCKOv2 library)	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	1.79090658420746	[]	[]	8	hSpCas9	negative selection	4022346
67711643	67711666	X	+	26780180	HT29	viability (GeCKOv2 library)	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	1.09526355405969	[]	[]	5	hSpCas9	negative selection	4022347
67686078	67686101	X	-	26780180	HT29	viability (GeCKOv2 library)	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.363125890557599	[]	[]	1	hSpCas9	negative selection	4022348
67686046	67686069	X	+	26780180	HT29	viability (GeCKOv2 library)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	1.22744878411738	[]	[]	6	hSpCas9	negative selection	4022349
67711563	67711586	X	-	26780180	HT29	viability (GeCKOv2 library)	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	1.75556280084565	[]	[]	8	hSpCas9	negative selection	4022350
67643386	67643409	X	+	26780180	HT29	viability (GeCKOv2 library)	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.668631646324898	[]	[]	2	hSpCas9	negative selection	4022351
67643319	67643342	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.16987559915419245	[4]	[2,2]	-4	hSpCas9	positive selection	4149314
67686078	67686101	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.33030231693830026	[2]	[0,1]	-7	hSpCas9	positive selection	4149325
67686046	67686069	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.07888983641684134	[3]	[1,2]	2	hSpCas9	positive selection	4149336
67643285	67643308	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	-0.023428128962528535	[4]	[2,2]	0	hSpCas9	positive selection	4149347
67643319	67643342	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.8278378884380577	[4]	[1,2,5,3]	5	hSpCas9	positive selection	4213336
67686078	67686101	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.7274290622114916	[2]	[3,3,1,0]	5	hSpCas9	positive selection	4213347
67686046	67686069	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.06998118791319655	[4]	[3,2,1,0]	0	hSpCas9	positive selection	4213358
67643285	67643308	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTGGAAAGTAATAGTCAATGG	AR	ENSG00000169083	-0.8988885835062635	[4]	[1,0,0,0]	-9	hSpCas9	positive selection	4213369
67686078	67686101	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.4105013424647953	[2]	[2,2]	8	hSpCas9	positive selection	4256320
67711563	67711586	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.24513117189518982	[3]	[3,2]	5	hSpCas9	positive selection	4256321
67686046	67686069	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.11124812859825073	[1]	[1,0]	-2	hSpCas9	positive selection	4256322
67643386	67643409	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.19333704643148567	[2]	[3,2]	4	hSpCas9	positive selection	4320604
67711643	67711666	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.32897415813150543	[3]	[3,3]	6	hSpCas9	positive selection	4320605
67643319	67643342	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.006223778533800635	[3]	[2,1]	0	hSpCas9	positive selection	4320606
67643393	67643415	X	+	27760321	OCIAML3	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	0.47736643317185806	[317,213]	[268,307]	6	hSpCas9	negative selection	4378926
67686023	67686045	X	-	27760321	OCIAML3	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.4914837117496995	[949,961]	[841,1332]	6	hSpCas9	negative selection	4378927
67686091	67686113	X	+	27760321	OCIAML3	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.6009325529860086	[254,232]	[87,174]	-5	hSpCas9	negative selection	4378928
67711402	67711424	X	-	27760321	OCIAML3	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	-0.7540489501950787	[709,534]	[330,227]	-6	hSpCas9	negative selection	4378929
67711419	67711441	X	+	27760321	OCIAML3	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	0.4619937782765755	[121,104]	[71,186]	5	hSpCas9	negative selection	4378930
67643393	67643415	X	+	27760321	OCIAML2	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.199730824056192	[317,213]	[430,562]	9	hSpCas9	negative selection	4462389
67686023	67686045	X	-	27760321	OCIAML2	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.39710070707231937	[949,961]	[938,1131]	5	hSpCas9	negative selection	4462390
67686091	67686113	X	+	27760321	OCIAML2	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.5191011063778537	[254,232]	[100,185]	-5	hSpCas9	negative selection	4462391
67711402	67711424	X	-	27760321	OCIAML2	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.18778851506165906	[709,534]	[444,731]	2	hSpCas9	negative selection	4462392
67711419	67711441	X	+	27760321	OCIAML2	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.512074081831225	[121,104]	[55,74]	-5	hSpCas9	negative selection	4462393
67643393	67643415	X	+	27760321	MV411	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.721920520930504	[317,213]	[633,477]	9	hSpCas9	negative selection	4545852
67686023	67686045	X	-	27760321	MV411	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.7822325485701209	[949,961]	[700,1671]	6	hSpCas9	negative selection	4545853
67686091	67686113	X	+	27760321	MV411	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.6283854265886326	[254,232]	[4,252]	-4	hSpCas9	negative selection	4545854
67711402	67711424	X	-	27760321	MV411	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	1.3562091997225914	[709,534]	[1265,707]	8	hSpCas9	negative selection	4545855
67711419	67711441	X	+	27760321	MV411	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-1.7256258091394088	[121,104]	[0,54]	-8	hSpCas9	negative selection	4545856
67643393	67643415	X	+	27760321	HL60	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	2.6048501265711184	[317,213]	[1137,1481]	9	hSpCas9	negative selection	4629315
67686023	67686045	X	-	27760321	HL60	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.09983857026908116	[949,961]	[858,819]	1	hSpCas9	negative selection	4629316
67686091	67686113	X	+	27760321	HL60	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.9925412041393002	[254,232]	[87,112]	-7	hSpCas9	negative selection	4629317
67711402	67711424	X	-	27760321	HL60	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	1.0090288848095526	[709,534]	[946,1086]	9	hSpCas9	negative selection	4629318
67711419	67711441	X	+	27760321	HL60	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	1.3398132589677454	[121,104]	[283,180]	9	hSpCas9	negative selection	4629319
67643393	67643415	X	+	27760321	HT1080	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.0849408884568164	[213,166]	[128,195]	6	hSpCas9	negative selection	4712778
67686023	67686045	X	-	27760321	HT1080	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.42780202684606294	[961,750]	[521,389]	2	hSpCas9	negative selection	4712779
67686091	67686113	X	+	27760321	HT1080	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-1.3642070049812118	[232,181]	[44,17]	-5	hSpCas9	negative selection	4712780
67711402	67711424	X	-	27760321	HT1080	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	1.279858308397131	[534,417]	[480,438]	7	hSpCas9	negative selection	4712781
67711419	67711441	X	+	27760321	HT1080	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.21583824011000208	[104,81]	[1,64]	-1	hSpCas9	negative selection	4712782
67643393	67643415	X	+	27760321	HT29	viability after 7 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	0.9101014420648572	[213,166]	[604,406,390]	9	hSpCas9	negative selection	4796241
67686023	67686045	X	-	27760321	HT29	viability after 7 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.30925812175521794	[961,750]	[1309,1575,1202]	5	hSpCas9	negative selection	4796242
67686091	67686113	X	+	27760321	HT29	viability after 7 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.8387782522958126	[232,181]	[175,121,152]	-8	hSpCas9	negative selection	4796243
67711402	67711424	X	-	27760321	HT29	viability after 7 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.5642779759251868	[534,417]	[907,1067,745]	8	hSpCas9	negative selection	4796244
67711419	67711441	X	+	27760321	HT29	viability after 7 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.951142430750546	[104,81]	[43,113,26]	-8	hSpCas9	negative selection	4796245
67643393	67643415	X	+	27760321	HT29	viability after 25 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.232550083742216	[213,166]	[435,622,475]	9	hSpCas9	negative selection	4879704
67686023	67686045	X	-	27760321	HT29	viability after 25 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.34731558918134886	[961,750]	[1331,1163,1230]	3	hSpCas9	negative selection	4879705
67686091	67686113	X	+	27760321	HT29	viability after 25 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.877788599181564	[232,181]	[109,141,136]	-6	hSpCas9	negative selection	4879706
67711402	67711424	X	-	27760321	HT29	viability after 25 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.5776716672204444	[534,417]	[708,840,902]	6	hSpCas9	negative selection	4879707
67711419	67711441	X	+	27760321	HT29	viability after 25 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.45850154127186094	[104,81]	[51,42,146]	-4	hSpCas9	negative selection	4879708
67643393	67643415	X	+	27760321	HT29	viability after 22 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.3323474577046444	[213,166]	[530,607,524]	9	hSpCas9	negative selection	4963167
67686023	67686045	X	-	27760321	HT29	viability after 22 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.09677388657372887	[961,750]	[950,1219,1007]	0	hSpCas9	negative selection	4963168
67686091	67686113	X	+	27760321	HT29	viability after 22 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.3165607618653782	[232,181]	[56,179,345]	-3	hSpCas9	negative selection	4963169
67711402	67711424	X	-	27760321	HT29	viability after 22 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.5345021435348131	[534,417]	[739,893,760]	6	hSpCas9	negative selection	4963170
67711419	67711441	X	+	27760321	HT29	viability after 22 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.5501226761647355	[104,81]	[84,79,55]	-5	hSpCas9	negative selection	4963171
67643393	67643415	X	+	27760321	HT29	viability after 19 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.6996805732827118	[213,166]	[658,709,746]	9	hSpCas9	negative selection	5046630
67686023	67686045	X	-	27760321	HT29	viability after 19 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.42663614603783184	[961,750]	[1523,1297,1154]	4	hSpCas9	negative selection	5046631
67686091	67686113	X	+	27760321	HT29	viability after 19 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.8856667648593436	[232,181]	[356,25,29]	-6	hSpCas9	negative selection	5046632
67711402	67711424	X	-	27760321	HT29	viability after 19 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.21998810074398367	[534,417]	[447,604,823]	2	hSpCas9	negative selection	5046633
67711419	67711441	X	+	27760321	HT29	viability after 19 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-1.805716340531659	[104,81]	[23,34,31]	-8	hSpCas9	negative selection	5046634
67643393	67643415	X	+	27760321	HT29	viability after 16 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.207550351432562	[213,166]	[516,526,433]	9	hSpCas9	negative selection	5130093
67686023	67686045	X	-	27760321	HT29	viability after 16 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.4347465849403158	[961,750]	[1284,1510,1082]	5	hSpCas9	negative selection	5130094
67686091	67686113	X	+	27760321	HT29	viability after 16 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	0.08310188049403744	[232,181]	[333,171,241]	0	hSpCas9	negative selection	5130095
67711402	67711424	X	-	27760321	HT29	viability after 16 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.5259145778638269	[534,417]	[904,644,768]	6	hSpCas9	negative selection	5130096
67711419	67711441	X	+	27760321	HT29	viability after 16 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.2689200751072691	[104,81]	[208,9,54]	-3	hSpCas9	negative selection	5130097
67643393	67643415	X	+	27760321	HT29	viability after 13 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	1.0352706906720213	[213,166]	[523,303,525]	9	hSpCas9	negative selection	5213556
67686023	67686045	X	-	27760321	HT29	viability after 13 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.22010524238119133	[961,750]	[1436,1057,986]	2	hSpCas9	negative selection	5213557
67686091	67686113	X	+	27760321	HT29	viability after 13 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.8287121719008489	[232,181]	[141,67,192]	-7	hSpCas9	negative selection	5213558
67711402	67711424	X	-	27760321	HT29	viability after 13 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.5404902823104883	[534,417]	[776,811,821]	7	hSpCas9	negative selection	5213559
67711419	67711441	X	+	27760321	HT29	viability after 13 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-0.5113902078415717	[104,81]	[65,97,64]	-5	hSpCas9	negative selection	5213560
67643393	67643415	X	+	27760321	HT29	viability after 10 days	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	0.5298253155891421	[213,166]	[184,531,318]	7	hSpCas9	negative selection	5297019
67686023	67686045	X	-	27760321	HT29	viability after 10 days	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	0.00753380245875368	[961,750]	[950,1213,1063]	0	hSpCas9	negative selection	5297020
67686091	67686113	X	+	27760321	HT29	viability after 10 days	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-0.6949593751421838	[232,181]	[170,192,117]	-7	hSpCas9	negative selection	5297021
67711402	67711424	X	-	27760321	HT29	viability after 10 days	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.513833978056744	[534,417]	[780,810,952]	7	hSpCas9	negative selection	5297022
67711419	67711441	X	+	27760321	HT29	viability after 10 days	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-1.5161087021199877	[104,81]	[71,37,12]	-8	hSpCas9	negative selection	5297023
67643393	67643415	X	+	27760321	MOLM13	viability	AAAGAGCCGCTGAAGGTAAAGG	AR	ENSG00000169083	0.9407602580241652	[317,213]	[83,454]	6	hSpCas9	negative selection	5380482
67686023	67686045	X	-	27760321	MOLM13	viability	ATCATTTCTGCTGGCGCACAGG	AR	ENSG00000169083	1.0462733504199435	[949,961]	[537,1611]	7	hSpCas9	negative selection	5380483
67686091	67686113	X	+	27760321	MOLM13	viability	TTCGGAAATGTTATGAAGCAGG	AR	ENSG00000169083	-1.1498774177151971	[254,232]	[81,44]	-6	hSpCas9	negative selection	5380484
67711402	67711424	X	-	27760321	MOLM13	viability	CCAAGTTTCTTCAGCTTCCGGG	AR	ENSG00000169083	0.12174845806201784	[709,534]	[506,269]	0	hSpCas9	negative selection	5380485
67711419	67711441	X	+	27760321	MOLM13	viability	CTTGGTAATCTGAAACTACAGG	AR	ENSG00000169083	-2.3710112404064563	[121,104]	[0,21]	-8	hSpCas9	negative selection	5380486
67544022	67544045	X	+	27661255	K562	viability	GCGCCCCCTCCGAGATCCCGGGG	AR	ENSG00000169083	-0.013044593660441143	[739,779]	[667,543]	0	dCas9-KRAB	negative selection	5462996
67544054	67544077	X	+	27661255	K562	viability	GCTGGGAGAGCGGGACGGTCCGG	AR	ENSG00000169083	0.10136934796451547	[378,449]	[399,314]	3	dCas9-KRAB	negative selection	5462997
67544025	67544048	X	-	27661255	K562	viability	GCTCCCCGGGATCTCGGAGGGGG	AR	ENSG00000169083	0.4334937833462278	[94,108]	[139,83]	9	dCas9-KRAB	negative selection	5462998
67544127	67544150	X	-	27661255	K562	viability	GCTCCTGTACAGCACTGGAGCGG	AR	ENSG00000169083	0.0393095288036836	[584,583]	[522,442]	1	dCas9-KRAB	negative selection	5462999
67686078	67686101	X	-	27260156	BXPC3	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.2863964861885697	[314]	[421,465,322,382]	6	hSpCas9	negative selection	5528780
67711563	67711586	X	-	27260156	BXPC3	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.17742137087944537	[565]	[669,554,720,742]	4	hSpCas9	negative selection	5528781
67686046	67686069	X	+	27260156	BXPC3	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.06518357062397895	[167]	[157,225,196,148]	1	hSpCas9	negative selection	5528782
67643386	67643409	X	+	27260156	BXPC3	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.2928090162431127	[456]	[450,488,698,739]	6	hSpCas9	negative selection	5593064
67711643	67711666	X	+	27260156	BXPC3	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.14920870399866848	[642]	[597,510,665,659]	-3	hSpCas9	negative selection	5593065
67643319	67643342	X	-	27260156	BXPC3	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.05918033760604774	[535]	[442,598,610,708]	1	hSpCas9	negative selection	5593066
67686078	67686101	X	-	27260156	A673	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5393078734319883	[314]	[573,520,615,485]	9	hSpCas9	negative selection	5650031
67711563	67711586	X	-	27260156	A673	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.30997941239442667	[565]	[875,865,788,840]	7	hSpCas9	negative selection	5650032
67686046	67686069	X	+	27260156	A673	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.10310397042750452	[167]	[185,124,233,207]	-3	hSpCas9	negative selection	5650033
67643386	67643409	X	+	27260156	A673	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.30125120009815615	[456]	[678,628,638,762]	7	hSpCas9	negative selection	5714315
67711643	67711666	X	+	27260156	A673	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3221444788702198	[642]	[683,604,547,641]	-7	hSpCas9	negative selection	5714316
67643319	67643342	X	-	27260156	A673	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.07258698836139371	[535]	[687,600,691,730]	1	hSpCas9	negative selection	5714317
67686078	67686101	X	-	27260156	A375	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5827626967800246	[314]	[416,651,686,468]	8	hSpCas9	negative selection	5771282
67711563	67711586	X	-	27260156	A375	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.4313738641729193	[565]	[854,1053,767,905]	6	hSpCas9	negative selection	5771283
67686046	67686069	X	+	27260156	A375	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.21039590629960436	[167]	[140,243,226,85]	-3	hSpCas9	negative selection	5771284
67643386	67643409	X	+	27260156	A375	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.6067387818928681	[456]	[770,1213,536,784]	8	hSpCas9	negative selection	5835566
67711643	67711666	X	+	27260156	A375	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.47982821791399166	[642]	[532,716,648,305]	-6	hSpCas9	negative selection	5835567
67643319	67643342	X	-	27260156	A375	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.30467328794055004	[535]	[720,1186,704,559]	4	hSpCas9	negative selection	5835568
67686078	67686101	X	-	27260156	COLO741	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.3687104056469311	[314]	[714,352,506]	7	hSpCas9	negative selection	5892533
67711563	67711586	X	-	27260156	COLO741	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.41667341966099275	[565]	[1175,821,916]	8	hSpCas9	negative selection	5892534
67686046	67686069	X	+	27260156	COLO741	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.06773539174082965	[167]	[340,117,168]	-1	hSpCas9	negative selection	5892535
67643386	67643409	X	+	27260156	COLO741	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.5631966731094508	[456]	[714,980,876]	9	hSpCas9	negative selection	5956817
67711643	67711666	X	+	27260156	COLO741	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.542433452609123	[642]	[653,473,569]	-8	hSpCas9	negative selection	5956818
67643319	67643342	X	-	27260156	COLO741	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.1800188860130683	[535]	[1080,687,595]	4	hSpCas9	negative selection	5956819
67686078	67686101	X	-	27260156	CAL120	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.18691468296043257	[314]	[489,407,446]	2	hSpCas9	negative selection	6013784
67711563	67711586	X	-	27260156	CAL120	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.48898145735693227	[565]	[1014,795,1154]	7	hSpCas9	negative selection	6013785
67686046	67686069	X	+	27260156	CAL120	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.5085583591320468	[167]	[239,207,432]	7	hSpCas9	negative selection	6013786
67643386	67643409	X	+	27260156	CAL120	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.7581339148456625	[456]	[757,1056,1037]	9	hSpCas9	negative selection	6078068
67711643	67711666	X	+	27260156	CAL120	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.6368565050957532	[642]	[633,496,431]	-7	hSpCas9	negative selection	6078069
67643319	67643342	X	-	27260156	CAL120	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.044169065976256305	[535]	[918,563,615]	0	hSpCas9	negative selection	6078070
67686078	67686101	X	-	27260156	CADOES1	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.28060011050443634	[314]	[348,302,322,451]	5	hSpCas9	negative selection	6135035
67711563	67711586	X	-	27260156	CADOES1	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.06106742796620446	[565]	[590,612,487,502]	1	hSpCas9	negative selection	6135036
67686046	67686069	X	+	27260156	CADOES1	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.08334433083766002	[167]	[127,134,110,292]	1	hSpCas9	negative selection	6135037
67643386	67643409	X	+	27260156	CADOES1	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.38435784131233114	[456]	[546,423,740,504]	6	hSpCas9	negative selection	6199319
67711643	67711666	X	+	27260156	CADOES1	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.10641163055976516	[642]	[612,395,440,779]	-2	hSpCas9	negative selection	6199320
67643319	67643342	X	-	27260156	CADOES1	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.09342217348221077	[535]	[596,491,434,605]	1	hSpCas9	negative selection	6199321
67686078	67686101	X	-	27260156	EWS502	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.6245116331688944	[314]	[434,632,569,415]	9	hSpCas9	negative selection	6256286
67711563	67711586	X	-	27260156	EWS502	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.583333261312077	[565]	[611,1078,1006,921]	8	hSpCas9	negative selection	6256287
67686046	67686069	X	+	27260156	EWS502	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.3145872842342843	[167]	[112,130,117,218]	-5	hSpCas9	negative selection	6256288
67643386	67643409	X	+	27260156	EWS502	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.3440397745447658	[456]	[507,657,772,522]	6	hSpCas9	negative selection	6320570
67711643	67711666	X	+	27260156	EWS502	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.4228947421997541	[642]	[490,411,605,529]	-6	hSpCas9	negative selection	6320571
67643319	67643342	X	-	27260156	EWS502	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.04707799155630912	[535]	[635,445,738,519]	0	hSpCas9	negative selection	6320572
67686078	67686101	X	-	27260156	EW8	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.23484410374951065	[314]	[352,179,310,359]	4	hSpCas9	negative selection	6377537
67711563	67711586	X	-	27260156	EW8	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.34121435704553865	[565]	[787,427,483,660]	6	hSpCas9	negative selection	6377538
67686046	67686069	X	+	27260156	EW8	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.565523330148965	[167]	[109,15,116,121]	-8	hSpCas9	negative selection	6377539
67643386	67643409	X	+	27260156	EW8	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.2586488690365059	[456]	[407,366,379,621]	5	hSpCas9	negative selection	6441821
67711643	67711666	X	+	27260156	EW8	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.5083787733741021	[642]	[412,352,452,235]	-7	hSpCas9	negative selection	6441822
67643319	67643342	X	-	27260156	EW8	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.08398062900378868	[535]	[445,435,381,382]	-1	hSpCas9	negative selection	6441823
67686078	67686101	X	-	27260156	CORL105	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5903861219947254	[314]	[567,364,622,678]	9	hSpCas9	negative selection	6498788
67711563	67711586	X	-	27260156	CORL105	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.36680451606034664	[565]	[686,885,1013,848]	6	hSpCas9	negative selection	6498789
67686046	67686069	X	+	27260156	CORL105	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.3022040228859293	[167]	[87,224,201,125]	-5	hSpCas9	negative selection	6498790
67643386	67643409	X	+	27260156	CORL105	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.19579070390656275	[456]	[706,533,645,573]	3	hSpCas9	negative selection	6563072
67711643	67711666	X	+	27260156	CORL105	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3619986939559945	[642]	[575,649,602,514]	-6	hSpCas9	negative selection	6563073
67643319	67643342	X	-	27260156	CORL105	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.11217784618974475	[535]	[526,739,828,633]	2	hSpCas9	negative selection	6563074
67686078	67686101	X	-	27260156	HS294T	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.4579676358897205	[314]	[214,82,185,185]	6	hSpCas9	negative selection	6620039
67711563	67711586	X	-	27260156	HS294T	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.29841197090722255	[565]	[191,325,299,261]	4	hSpCas9	negative selection	6620040
67686046	67686069	X	+	27260156	HS294T	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.5836939420545184	[167]	[31,31,35,80]	-7	hSpCas9	negative selection	6620041
67643386	67643409	X	+	27260156	HS294T	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.2763014164181123	[456]	[236,209,212,188]	4	hSpCas9	negative selection	6684323
67711643	67711666	X	+	27260156	HS294T	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.039255566714540446	[642]	[123,390,202,257]	0	hSpCas9	negative selection	6684324
67643319	67643342	X	-	27260156	HS294T	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.1341626380723956	[535]	[112,263,228,329]	1	hSpCas9	negative selection	6684325
67686078	67686101	X	-	27260156	HCC44	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.262674206288132	[314]	[381,252,867,303]	4	hSpCas9	negative selection	6741290
67711563	67711586	X	-	27260156	HCC44	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.13149480320833162	[565]	[700,798,841,474]	2	hSpCas9	negative selection	6741291
67686046	67686069	X	+	27260156	HCC44	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.05004596609394074	[167]	[194,165,148,218]	-1	hSpCas9	negative selection	6741292
67643386	67643409	X	+	27260156	HCC44	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.6219563397520032	[456]	[1140,693,725,652]	8	hSpCas9	negative selection	6805574
67711643	67711666	X	+	27260156	HCC44	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.6499319691180855	[642]	[397,418,563,485]	-7	hSpCas9	negative selection	6805575
67643319	67643342	X	-	27260156	HCC44	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.0527150289898983	[535]	[616,572,607,544]	-1	hSpCas9	negative selection	6805576
67686078	67686101	X	-	27260156	G402	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.2532529368617829	[314]	[471,587,443,341]	3	hSpCas9	negative selection	6862541
67711563	67711586	X	-	27260156	G402	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.656674731819139	[565]	[1028,1149,1232,940]	7	hSpCas9	negative selection	6862542
67686046	67686069	X	+	27260156	G402	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.0005670683120830855	[167]	[146,272,179,213]	0	hSpCas9	negative selection	6862543
67643386	67643409	X	+	27260156	G402	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.7876530163941539	[456]	[1349,889,558,1092]	8	hSpCas9	negative selection	6926825
67711643	67711666	X	+	27260156	G402	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.10362979328592403	[642]	[992,1027,576,391]	-1	hSpCas9	negative selection	6926826
67643319	67643342	X	-	27260156	G402	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.20879773764674148	[535]	[482,630,610,529]	-3	hSpCas9	negative selection	6926827
67686078	67686101	X	-	27260156	L33	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5825934269386354	[314]	[479,244,237,429]	9	hSpCas9	negative selection	6983792
67711563	67711586	X	-	27260156	L33	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.22161690614804236	[565]	[659,263,423,660]	5	hSpCas9	negative selection	6983793
67686046	67686069	X	+	27260156	L33	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.14691763662312662	[167]	[248,78,104,133]	3	hSpCas9	negative selection	6983794
67643386	67643409	X	+	27260156	L33	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.0677182057819217	[456]	[462,195,275,534]	1	hSpCas9	negative selection	7048076
67711643	67711666	X	+	27260156	L33	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.2741559636693024	[642]	[632,189,348,472]	-6	hSpCas9	negative selection	7048077
67643319	67643342	X	-	27260156	L33	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.16343792188456346	[535]	[525,157,274,562]	-4	hSpCas9	negative selection	7048078
67686078	67686101	X	-	27260156	K562	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.31727899883581057	[314]	[252,522,267,348]	4	hSpCas9	negative selection	7105043
67711563	67711586	X	-	27260156	K562	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.4487075175872988	[565]	[599,676,818,640]	5	hSpCas9	negative selection	7105044
67686046	67686069	X	+	27260156	K562	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.05074171828826879	[167]	[92,58,180,223]	0	hSpCas9	negative selection	7105045
67643386	67643409	X	+	27260156	K562	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.49502781620463576	[456]	[742,634,330,589]	6	hSpCas9	negative selection	7169327
67711643	67711666	X	+	27260156	K562	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.40343935552883176	[642]	[809,834,1129,302]	5	hSpCas9	negative selection	7169328
67643319	67643342	X	-	27260156	K562	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.20662161247619817	[535]	[370,456,471,352]	-3	hSpCas9	negative selection	7169329
67686078	67686101	X	-	27260156	HT29	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5951793245243454	[314]	[600,667,587,474]	9	hSpCas9	negative selection	7226294
67711563	67711586	X	-	27260156	HT29	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.2671632527223186	[565]	[882,857,951,642]	5	hSpCas9	negative selection	7226295
67686046	67686069	X	+	27260156	HT29	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.6473245115992646	[167]	[315,305,336,316]	9	hSpCas9	negative selection	7226296
67643386	67643409	X	+	27260156	HT29	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.6072588247822224	[456]	[832,1175,602,799]	9	hSpCas9	negative selection	7290578
67711643	67711666	X	+	27260156	HT29	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.42470197583394004	[642]	[794,483,597,469]	-7	hSpCas9	negative selection	7290579
67643319	67643342	X	-	27260156	HT29	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.02080438753278588	[535]	[767,720,711,474]	0	hSpCas9	negative selection	7290580
67686078	67686101	X	-	27260156	MHHES1	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.4342033211287724	[314]	[462,602,506,369]	7	hSpCas9	negative selection	7347545
67711563	67711586	X	-	27260156	MHHES1	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.511236512871567	[565]	[753,1164,1026,719]	8	hSpCas9	negative selection	7347546
67686046	67686069	X	+	27260156	MHHES1	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.4069063025089228	[167]	[130,109,158,158]	-6	hSpCas9	negative selection	7347547
67643386	67643409	X	+	27260156	MHHES1	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.2752688352829167	[456]	[639,692,551,604]	5	hSpCas9	negative selection	7411829
67711643	67711666	X	+	27260156	MHHES1	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.05125040366155925	[642]	[1218,824,638,272]	-1	hSpCas9	negative selection	7411830
67643319	67643342	X	-	27260156	MHHES1	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.33128808677794996	[535]	[743,368,416,413]	-6	hSpCas9	negative selection	7411831
67686078	67686101	X	-	27260156	MEWO	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.16929821389826727	[314]	[372,366,261]	4	hSpCas9	negative selection	7468796
67711563	67711586	X	-	27260156	MEWO	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.1272723533543515	[565]	[643,512,590]	3	hSpCas9	negative selection	7468797
67686046	67686069	X	+	27260156	MEWO	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.32810434355165685	[167]	[267,111,225]	7	hSpCas9	negative selection	7468798
67643386	67643409	X	+	27260156	MEWO	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.3107156507239901	[456]	[557,561,475]	6	hSpCas9	negative selection	7533080
67711643	67711666	X	+	27260156	MEWO	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3994262925521745	[642]	[505,418,452]	-7	hSpCas9	negative selection	7533081
67643319	67643342	X	-	27260156	MEWO	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.2927107283589274	[535]	[574,434,249]	-6	hSpCas9	negative selection	7533082
67686078	67686101	X	-	27260156	LNCAPCLONEFGC	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.9726700582454042	[314]	[198,86,122,171]	-8	hSpCas9	negative selection	7590047
67711563	67711586	X	-	27260156	LNCAPCLONEFGC	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	-0.3729261024856618	[565]	[339,443,487,322]	-5	hSpCas9	negative selection	7590048
67686046	67686069	X	+	27260156	LNCAPCLONEFGC	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-1.741282017967315	[167]	[33,91,23,25]	-9	hSpCas9	negative selection	7590049
67643386	67643409	X	+	27260156	LNCAPCLONEFGC	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	-1.272637351600909	[456]	[172,133,233,155]	-9	hSpCas9	negative selection	7654331
67711643	67711666	X	+	27260156	LNCAPCLONEFGC	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.18109669259497646	[642]	[379,474,460,735]	-3	hSpCas9	negative selection	7654332
67643319	67643342	X	-	27260156	LNCAPCLONEFGC	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-1.5272146080656483	[535]	[133,147,176,217]	-9	hSpCas9	negative selection	7654333
67686078	67686101	X	-	27260156	PANC0327	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5420177504190926	[314]	[350,576,358,315]	7	hSpCas9	negative selection	7711298
67711563	67711586	X	-	27260156	PANC0327	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.3387698907560845	[565]	[1142,492,437,528]	5	hSpCas9	negative selection	7711299
67686046	67686069	X	+	27260156	PANC0327	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.15819795935190695	[167]	[155,115,297,101]	2	hSpCas9	negative selection	7711300
67643386	67643409	X	+	27260156	PANC0327	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.27745369743164927	[456]	[330,436,585,607]	4	hSpCas9	negative selection	7775582
67711643	67711666	X	+	27260156	PANC0327	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.15838290946966815	[642]	[317,376,799,553]	-2	hSpCas9	negative selection	7775583
67643319	67643342	X	-	27260156	PANC0327	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.5050640264857088	[535]	[954,643,749,380]	7	hSpCas9	negative selection	7775584
67686078	67686101	X	-	27260156	NCIH2009	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.6581531114809794	[314]	[674,721,680]	8	hSpCas9	negative selection	7832549
67711563	67711586	X	-	27260156	NCIH2009	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.3525117348782541	[565]	[1018,1071,936]	5	hSpCas9	negative selection	7832550
67686046	67686069	X	+	27260156	NCIH2009	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.1698290119559729	[167]	[287,224,127]	-2	hSpCas9	negative selection	7832551
67643386	67643409	X	+	27260156	NCIH2009	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.7847647996084157	[456]	[883,740,1636]	9	hSpCas9	negative selection	7896833
67711643	67711666	X	+	27260156	NCIH2009	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.08816722988151582	[642]	[1012,794,759]	-1	hSpCas9	negative selection	7896834
67643319	67643342	X	-	27260156	NCIH2009	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.11729109064256399	[535]	[967,773,724]	1	hSpCas9	negative selection	7896835
67686078	67686101	X	-	27260156	NCIH1373	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.012804128661910053	[314]	[250,252,418,131]	0	hSpCas9	negative selection	7953800
67711563	67711586	X	-	27260156	NCIH1373	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.34674031146989887	[565]	[821,999,621,199]	3	hSpCas9	negative selection	7953801
67686046	67686069	X	+	27260156	NCIH1373	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.09626884366530164	[167]	[93,120,191,77]	-1	hSpCas9	negative selection	7953802
67643386	67643409	X	+	27260156	NCIH1373	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.11139057715129577	[456]	[661,476,614,124]	1	hSpCas9	negative selection	8018084
67711643	67711666	X	+	27260156	NCIH1373	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.038914637661672025	[642]	[1216,598,639,110]	0	hSpCas9	negative selection	8018085
67643319	67643342	X	-	27260156	NCIH1373	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.5794668431591115	[535]	[409,432,403,92]	-5	hSpCas9	negative selection	8018086
67686078	67686101	X	-	27260156	PATU8902	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5348766978441515	[314]	[450,848,533,745]	5	hSpCas9	negative selection	8075051
67711563	67711586	X	-	27260156	PATU8902	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.5664966950384642	[565]	[1216,1154,1027,1312]	6	hSpCas9	negative selection	8075052
67686046	67686069	X	+	27260156	PATU8902	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.18610037598799312	[167]	[237,121,179,297]	-2	hSpCas9	negative selection	8075053
67643386	67643409	X	+	27260156	PATU8902	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.8851796751001618	[456]	[2053,947,634,1184]	8	hSpCas9	negative selection	8139335
67711643	67711666	X	+	27260156	PATU8902	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.5449140227771814	[642]	[1534,1548,606,1757]	5	hSpCas9	negative selection	8139336
67643319	67643342	X	-	27260156	PATU8902	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.5652495795272363	[535]	[853,866,972,1839]	6	hSpCas9	negative selection	8139337
67686078	67686101	X	-	27260156	PANC1	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.42687739545693837	[314]	[355,471,341,309]	7	hSpCas9	negative selection	8196302
67711563	67711586	X	-	27260156	PANC1	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.31056331149233446	[565]	[615,891,456,509]	5	hSpCas9	negative selection	8196303
67686046	67686069	X	+	27260156	PANC1	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.060843318382171274	[167]	[162,128,174,89]	-1	hSpCas9	negative selection	8196304
67643386	67643409	X	+	27260156	PANC1	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.28068270217388186	[456]	[447,783,310,426]	4	hSpCas9	negative selection	8260586
67711643	67711666	X	+	27260156	PANC1	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.38486109956327075	[642]	[298,547,513,362]	-6	hSpCas9	negative selection	8260587
67643319	67643342	X	-	27260156	PANC1	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.26929800280312327	[535]	[726,550,483,458]	4	hSpCas9	negative selection	8260588
67686078	67686101	X	-	27260156	PANC0813	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.28236814667573845	[314]	[606,468,475,271]	4	hSpCas9	negative selection	8317553
67711563	67711586	X	-	27260156	PANC0813	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.2742820331486108	[565]	[747,896,786,778]	4	hSpCas9	negative selection	8317554
67686046	67686069	X	+	27260156	PANC0813	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.10181147974067528	[167]	[232,132,287,195]	1	hSpCas9	negative selection	8317555
67643386	67643409	X	+	27260156	PANC0813	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.3354230015085543	[456]	[709,611,756,634]	5	hSpCas9	negative selection	8381837
67711643	67711666	X	+	27260156	PANC0813	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.16744494289994277	[642]	[841,526,530,796]	-3	hSpCas9	negative selection	8381838
67643319	67643342	X	-	27260156	PANC0813	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.6158478798754323	[535]	[492,347,547,269]	-7	hSpCas9	negative selection	8381839
67686078	67686101	X	-	27260156	RDES	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.5980241137753873	[314]	[520,482,665,516]	8	hSpCas9	negative selection	8438804
67711563	67711586	X	-	27260156	RDES	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.48708029995534036	[565]	[639,906,1162,994]	7	hSpCas9	negative selection	8438805
67686046	67686069	X	+	27260156	RDES	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.5394082285097384	[167]	[150,115,110,147]	-7	hSpCas9	negative selection	8438806
67643386	67643409	X	+	27260156	RDES	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.3247362257832415	[456]	[515,626,672,862]	5	hSpCas9	negative selection	8503088
67711643	67711666	X	+	27260156	RDES	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.10116490421715202	[642]	[607,739,742,652]	-2	hSpCas9	negative selection	8503089
67643319	67643342	X	-	27260156	RDES	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.04674220430096365	[535]	[591,547,695,723]	0	hSpCas9	negative selection	8503090
67686078	67686101	X	-	27260156	PC3	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.34089705596056213	[314]	[319,304,529,481]	7	hSpCas9	negative selection	8560055
67711563	67711586	X	-	27260156	PC3	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.37250206628809174	[565]	[429,890,1139,670]	7	hSpCas9	negative selection	8560056
67686046	67686069	X	+	27260156	PC3	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.05249875157022532	[167]	[89,149,334,207]	1	hSpCas9	negative selection	8560057
67643386	67643409	X	+	27260156	PC3	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.13704252536454928	[456]	[318,356,1151,467]	3	hSpCas9	negative selection	8624339
67711643	67711666	X	+	27260156	PC3	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.5104911859162427	[642]	[277,500,651,476]	-8	hSpCas9	negative selection	8624340
67643319	67643342	X	-	27260156	PC3	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.04515617688865134	[535]	[362,529,1024,496]	1	hSpCas9	negative selection	8624341
67686078	67686101	X	-	27260156	PATU8988T	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.19561196158997496	[314]	[538,328,195,328]	3	hSpCas9	negative selection	8681306
67711563	67711586	X	-	27260156	PATU8988T	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.13206187863867946	[565]	[392,777,519,734]	2	hSpCas9	negative selection	8681307
67686046	67686069	X	+	27260156	PATU8988T	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.4403682212800586	[167]	[359,93,181,234]	7	hSpCas9	negative selection	8681308
67643386	67643409	X	+	27260156	PATU8988T	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.20843184050723662	[456]	[557,578,428,479]	3	hSpCas9	negative selection	8745590
67711643	67711666	X	+	27260156	PATU8988T	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.45459894892496017	[642]	[536,439,384,450]	-6	hSpCas9	negative selection	8745591
67643319	67643342	X	-	27260156	PATU8988T	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.1335270018754055	[535]	[331,478,489,597]	-2	hSpCas9	negative selection	8745592
67686078	67686101	X	-	27260156	T47D	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.48191748005216173	[314]	[534,492,524,497]	8	hSpCas9	negative selection	8802557
67711563	67711586	X	-	27260156	T47D	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.16572976010523693	[565]	[711,650,780,823]	3	hSpCas9	negative selection	8802558
67686046	67686069	X	+	27260156	T47D	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.18633871755593212	[167]	[213,235,188,251]	4	hSpCas9	negative selection	8802559
67643386	67643409	X	+	27260156	T47D	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.32947983238061307	[456]	[680,638,710,645]	7	hSpCas9	negative selection	8866841
67711643	67711666	X	+	27260156	T47D	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3868955308243286	[642]	[622,561,617,485]	-7	hSpCas9	negative selection	8866842
67643319	67643342	X	-	27260156	T47D	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.03853048254249297	[535]	[632,650,542,741]	0	hSpCas9	negative selection	8866843
67686078	67686101	X	-	27260156	SU8686	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.03399073753882176	[314]	[291,356,370,243]	0	hSpCas9	negative selection	8923808
67711563	67711586	X	-	27260156	SU8686	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.31253006766339914	[565]	[563,646,694,936]	5	hSpCas9	negative selection	8923809
67686046	67686069	X	+	27260156	SU8686	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	0.2547555354308937	[167]	[153,224,109,323]	4	hSpCas9	negative selection	8923810
67643386	67643409	X	+	27260156	SU8686	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.3557499077584187	[456]	[643,529,480,670]	6	hSpCas9	negative selection	8988092
67711643	67711666	X	+	27260156	SU8686	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.48451504404579215	[642]	[477,382,526,436]	-6	hSpCas9	negative selection	8988093
67643319	67643342	X	-	27260156	SU8686	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.05593384770920712	[535]	[531,622,587,437]	0	hSpCas9	negative selection	8988094
67686078	67686101	X	-	27260156	SKES1	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.377231269356076	[314]	[397,373,408,437]	7	hSpCas9	negative selection	9045059
67711563	67711586	X	-	27260156	SKES1	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.163943643008108	[565]	[779,720,575,494]	3	hSpCas9	negative selection	9045060
67686046	67686069	X	+	27260156	SKES1	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.2384219835205561	[167]	[175,185,66,147]	-5	hSpCas9	negative selection	9045061
67643386	67643409	X	+	27260156	SKES1	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.4444048865192672	[456]	[656,612,751,472]	8	hSpCas9	negative selection	9109343
67711643	67711666	X	+	27260156	SKES1	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.5339036065197302	[642]	[446,567,362,409]	-8	hSpCas9	negative selection	9109344
67643319	67643342	X	-	27260156	SKES1	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.12534657749031675	[535]	[512,583,452,427]	-3	hSpCas9	negative selection	9109345
67686078	67686101	X	-	27260156	TOV112D	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.4652063119487773	[314]	[395,456,549,342]	8	hSpCas9	negative selection	9166310
67711563	67711586	X	-	27260156	TOV112D	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.1558020275094732	[565]	[755,703,520,573]	3	hSpCas9	negative selection	9166311
67686046	67686069	X	+	27260156	TOV112D	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.09012292897965324	[167]	[166,160,201,104]	-2	hSpCas9	negative selection	9166312
67643386	67643409	X	+	27260156	TOV112D	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.5771370548703862	[456]	[643,776,712,617]	9	hSpCas9	negative selection	9230594
67711643	67711666	X	+	27260156	TOV112D	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.3430108224122834	[642]	[568,541,328,600]	-6	hSpCas9	negative selection	9230595
67643319	67643342	X	-	27260156	TOV112D	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.41742637126925575	[535]	[653,1025,416,836]	7	hSpCas9	negative selection	9230596
67686078	67686101	X	-	27260156	TC71	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.43140307639612474	[314]	[429,454,431,508]	8	hSpCas9	negative selection	9287561
67711563	67711586	X	-	27260156	TC71	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.15303261611153002	[565]	[574,846,584,697]	4	hSpCas9	negative selection	9287562
67686046	67686069	X	+	27260156	TC71	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.0761407845008728	[167]	[146,173,172,190]	-2	hSpCas9	negative selection	9287563
67643386	67643409	X	+	27260156	TC71	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.2543100208208908	[456]	[519,667,528,625]	6	hSpCas9	negative selection	9351845
67711643	67711666	X	+	27260156	TC71	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.5493220646938283	[642]	[484,429,444,527]	-9	hSpCas9	negative selection	9351846
67643319	67643342	X	-	27260156	TC71	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	-0.15987622344250582	[535]	[453,527,400,689]	-4	hSpCas9	negative selection	9351847
67686078	67686101	X	-	27260156	TC32	viability	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.33763949628146833	[314]	[330,295,495,408]	6	hSpCas9	negative selection	9408812
67711563	67711586	X	-	27260156	TC32	viability	TGTCCAGCACACACTACACCTGG	AR	ENSG00000169083	0.2812284992812037	[565]	[630,423,916,712]	5	hSpCas9	negative selection	9408813
67686046	67686069	X	+	27260156	TC32	viability	GCACTATTGATAAATTCCGAAGG	AR	ENSG00000169083	-0.0972163962803434	[167]	[252,63,182,102]	-2	hSpCas9	negative selection	9408814
67643386	67643409	X	+	27260156	TC32	viability	TTCTTCAAAAGAGCCGCTGAAGG	AR	ENSG00000169083	0.4017565900129804	[456]	[380,520,785,629]	7	hSpCas9	negative selection	9473096
67711643	67711666	X	+	27260156	TC32	viability	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	-0.052387331575953155	[642]	[538,345,950,623]	-1	hSpCas9	negative selection	9473097
67643319	67643342	X	-	27260156	TC32	viability	AAGCTTCATCTCCACAGATCAGG	AR	ENSG00000169083	0.13365647375019146	[535]	[570,332,597,777]	2	hSpCas9	negative selection	9473098
67545890	67545913	X	-	27869803	HPAFII	viability after 27 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.5586548799511718	[194]	[120,175,NaN]	4	hSpCas9	negative selection	9609348
67569004	67569027	X	+	27869803	HPAFII	viability after 27 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.9157428901912006	[177]	[199,156,NaN]	7	hSpCas9	negative selection	9609349
67686078	67686101	X	-	27869803	HPAFII	viability after 27 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.16223305883967476	[139]	[137,35,NaN]	1	hSpCas9	negative selection	9609350
67694680	67694703	X	-	27869803	HPAFII	viability after 27 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.18324524994402158	[112]	[103,36,NaN]	1	hSpCas9	negative selection	9609351
67711643	67711666	X	+	27869803	HPAFII	viability after 27 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.6292257273513591	[526]	[523,348,NaN]	5	hSpCas9	negative selection	9609352
67717488	67717511	X	+	27869803	HPAFII	viability after 27 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.9096557573414622	[152]	[80,10,NaN]	-6	hSpCas9	negative selection	9609353
67545890	67545913	X	-	27869803	HPAFII	viability after 15 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.4142229656554711	[194]	[335,243,NaN]	5	hSpCas9	negative selection	9691797
67569004	67569027	X	+	27869803	HPAFII	viability after 15 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.6046156921643226	[177]	[346,255,NaN]	7	hSpCas9	negative selection	9691798
67686078	67686101	X	-	27869803	HPAFII	viability after 15 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.31529914057197117	[139]	[349,85,NaN]	3	hSpCas9	negative selection	9691799
67694680	67694703	X	-	27869803	HPAFII	viability after 15 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	-0.3532248026591023	[112]	[136,68,NaN]	-4	hSpCas9	negative selection	9691800
67711643	67711666	X	+	27869803	HPAFII	viability after 15 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.6085517597257017	[526]	[997,779,NaN]	7	hSpCas9	negative selection	9691801
67717488	67717511	X	+	27869803	HPAFII	viability after 15 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.41002591883985373	[152]	[169,94,NaN]	-4	hSpCas9	negative selection	9691802
67545890	67545913	X	-	27869803	ASPC1	viability after 36 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	-0.26424844249085405	[622]	[274,125,156]	-3	hSpCas9	negative selection	9774246
67569004	67569027	X	+	27869803	ASPC1	viability after 36 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.12965718545254687	[571]	[323,176,174]	1	hSpCas9	negative selection	9774247
67686078	67686101	X	-	27869803	ASPC1	viability after 36 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.847203948568964	[382]	[199,332,192]	7	hSpCas9	negative selection	9774248
67694680	67694703	X	-	27869803	ASPC1	viability after 36 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.5882559462435206	[217]	[223,8,119]	6	hSpCas9	negative selection	9774249
67711643	67711666	X	+	27869803	ASPC1	viability after 36 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	1.0179975310123928	[1362]	[976,873,1014]	8	hSpCas9	negative selection	9774250
67717488	67717511	X	+	27869803	ASPC1	viability after 36 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.2500909955563322	[238]	[103,104,17]	-3	hSpCas9	negative selection	9774251
67545890	67545913	X	-	27869803	PATU8988S	viability after 35 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.30242719594364126	[548]	[130,414,NaN]	3	hSpCas9	negative selection	9856695
67569004	67569027	X	+	27869803	PATU8988S	viability after 35 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.7654585553470458	[423]	[415,163,NaN]	7	hSpCas9	negative selection	9856696
67686078	67686101	X	-	27869803	PATU8988S	viability after 35 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.9948971124082937	[271]	[40,68,NaN]	-7	hSpCas9	negative selection	9856697
67694680	67694703	X	-	27869803	PATU8988S	viability after 35 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.34233714764520773	[189]	[103,89,NaN]	4	hSpCas9	negative selection	9856698
67711643	67711666	X	+	27869803	PATU8988S	viability after 35 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.18435065792692162	[1442]	[609,710,NaN]	2	hSpCas9	negative selection	9856699
67717488	67717511	X	+	27869803	PATU8988S	viability after 35 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.006908480514001725	[281]	[166,60,NaN]	0	hSpCas9	negative selection	9856700
67545890	67545913	X	-	27869803	PATU8988S	viability after 31 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.3935700112471548	[548]	[137,477,NaN]	5	hSpCas9	negative selection	9939144
67569004	67569027	X	+	27869803	PATU8988S	viability after 31 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.49970096294617883	[423]	[275,191,NaN]	6	hSpCas9	negative selection	9939145
67686078	67686101	X	-	27869803	PATU8988S	viability after 31 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	-0.9881069619283638	[271]	[44,66,NaN]	-7	hSpCas9	negative selection	9939146
67694680	67694703	X	-	27869803	PATU8988S	viability after 31 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.48070001192936984	[189]	[99,112,NaN]	6	hSpCas9	negative selection	9939147
67711643	67711666	X	+	27869803	PATU8988S	viability after 31 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.3342382282916838	[1442]	[709,744,NaN]	4	hSpCas9	negative selection	9939148
67717488	67717511	X	+	27869803	PATU8988S	viability after 31 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.272589260557465	[281]	[122,54,NaN]	-3	hSpCas9	negative selection	9939149
67545890	67545913	X	-	27869803	HPAFII	viability after 35 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	1.1951390407085596	[194]	[170,287,NaN]	7	hSpCas9	negative selection	10021593
67569004	67569027	X	+	27869803	HPAFII	viability after 35 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.865262536853563	[177]	[237,80,NaN]	6	hSpCas9	negative selection	10021594
67686078	67686101	X	-	27869803	HPAFII	viability after 35 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.37872089085139443	[139]	[157,17,NaN]	2	hSpCas9	negative selection	10021595
67694680	67694703	X	-	27869803	HPAFII	viability after 35 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.3772075709793873	[112]	[86,59,NaN]	2	hSpCas9	negative selection	10021596
67711643	67711666	X	+	27869803	HPAFII	viability after 35 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.7421984563026907	[526]	[513,369,NaN]	5	hSpCas9	negative selection	10021597
67717488	67717511	X	+	27869803	HPAFII	viability after 35 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	0.2068270929326812	[152]	[55,126,NaN]	1	hSpCas9	negative selection	10021598
67545890	67545913	X	-	27869803	HPAFII	viability after 31 days	GCTCCAACGCCTCCACACCCAGG	AR	ENSG00000169083	0.9986146809495855	[194]	[199,238,NaN]	7	hSpCas9	negative selection	10104042
67569004	67569027	X	+	27869803	HPAFII	viability after 31 days	TGATACTCTGGCTTCACAGGTGG	AR	ENSG00000169083	0.7821040253086602	[177]	[233,103,NaN]	6	hSpCas9	negative selection	10104043
67686078	67686101	X	-	27869803	HPAFII	viability after 31 days	CATTTCCGAAGACGACAAGATGG	AR	ENSG00000169083	0.8050508173167142	[139]	[243,20,NaN]	6	hSpCas9	negative selection	10104044
67694680	67694703	X	-	27869803	HPAFII	viability after 31 days	GATGCTTGCAATTGCCAACCCGG	AR	ENSG00000169083	0.018977166092920328	[112]	[69,57,NaN]	0	hSpCas9	negative selection	10104045
67711643	67711666	X	+	27869803	HPAFII	viability after 31 days	AGAGAGACAGCTTGTACACGTGG	AR	ENSG00000169083	0.6060656237263409	[526]	[509,384,NaN]	4	hSpCas9	negative selection	10104046
67717488	67717511	X	+	27869803	HPAFII	viability after 31 days	CTTACACGTGGACGACCAGATGG	AR	ENSG00000169083	-0.505494105954771	[152]	[48,72,NaN]	-3	hSpCas9	negative selection	10104047
67722926	67722949	X	-	28162770	P31FUJ	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.17961554647638445	[688]	[916]	2	hSpCas9	negative selection	10112565
67711658	67711681	X	+	28162770	P31FUJ	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	-0.03754591301544474	[137]	[157]	0	hSpCas9	negative selection	10112566
67711430	67711453	X	+	28162770	P31FUJ	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.6940313830236498	[90]	[172]	7	hSpCas9	negative selection	10112567
67686105	67686128	X	+	28162770	P31FUJ	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.12819545515157588	[203]	[261]	1	hSpCas9	negative selection	10112568
67717476	67717499	X	+	28162770	P31FUJ	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.19718563633043662	[287]	[387]	2	hSpCas9	negative selection	10112569
67717533	67717556	X	+	28162770	P31FUJ	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.006385459465047427	[121]	[143]	0	hSpCas9	negative selection	10112570
67721832	67721855	X	+	28162770	P31FUJ	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.9807497294281917	[303]	[704]	9	hSpCas9	negative selection	10112571
67722813	67722836	X	+	28162770	P31FUJ	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.40774705804509237	[890]	[1388]	4	hSpCas9	negative selection	10112572
67643308	67643331	X	+	28162770	P31FUJ	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	1.0634392468093343	[67]	[166]	9	hSpCas9	negative selection	10112573
67711457	67711480	X	+	28162770	P31FUJ	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	0.30163554676397053	[338]	[490]	3	hSpCas9	negative selection	10112574
67722926	67722949	X	-	28162770	TF1	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10281931
67711658	67711681	X	+	28162770	TF1	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10281932
67711430	67711453	X	+	28162770	TF1	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10281933
67686105	67686128	X	+	28162770	TF1	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10281934
67717476	67717499	X	+	28162770	TF1	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	NaN	[NaN]	[391]	1	hSpCas9	negative selection	10281935
67717533	67717556	X	+	28162770	TF1	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10281936
67721832	67721855	X	+	28162770	TF1	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	NaN	[NaN]	[386]	1	hSpCas9	negative selection	10281937
67722813	67722836	X	+	28162770	TF1	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	NaN	[NaN]	[882]	1	hSpCas9	negative selection	10281938
67643308	67643331	X	+	28162770	TF1	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10281939
67711457	67711480	X	+	28162770	TF1	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10281940
67722926	67722949	X	-	28162770	SKM1	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.5977489548798673	[190]	[510]	6	hSpCas9	negative selection	10451297
67711658	67711681	X	+	28162770	SKM1	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.8243613473632941	[22]	[71]	7	hSpCas9	negative selection	10451298
67711430	67711453	X	+	28162770	SKM1	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.2654611432283339	[31]	[67]	2	hSpCas9	negative selection	10451299
67686105	67686128	X	+	28162770	SKM1	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.21713963986314444	[95]	[145]	-2	hSpCas9	negative selection	10451300
67717476	67717499	X	+	28162770	SKM1	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.31865870891511205	[82]	[182]	3	hSpCas9	negative selection	10451301
67717533	67717556	X	+	28162770	SKM1	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.05935380547937541	[37]	[69]	0	hSpCas9	negative selection	10451302
67721832	67721855	X	+	28162770	SKM1	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.30610312772567977	[69]	[152]	3	hSpCas9	negative selection	10451303
67722813	67722836	X	+	28162770	SKM1	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	-0.07178000715353261	[194]	[327]	0	hSpCas9	negative selection	10451304
67643308	67643331	X	+	28162770	SKM1	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	1.0039689022029454	[10]	[38]	8	hSpCas9	negative selection	10451305
67711457	67711480	X	+	28162770	SKM1	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.2516859732652507	[65]	[97]	-2	hSpCas9	negative selection	10451306
67722926	67722949	X	-	28162770	SKM1	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.5977489548798673	[190]	[510]	6	hSpCas9	negative selection	10620663
67711658	67711681	X	+	28162770	SKM1	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.8243613473632941	[22]	[71]	7	hSpCas9	negative selection	10620664
67711430	67711453	X	+	28162770	SKM1	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.2654611432283339	[31]	[67]	2	hSpCas9	negative selection	10620665
67686105	67686128	X	+	28162770	SKM1	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.21713963986314444	[95]	[145]	-2	hSpCas9	negative selection	10620666
67717476	67717499	X	+	28162770	SKM1	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.31865870891511205	[82]	[182]	3	hSpCas9	negative selection	10620667
67717533	67717556	X	+	28162770	SKM1	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.05935380547937541	[37]	[69]	0	hSpCas9	negative selection	10620668
67721832	67721855	X	+	28162770	SKM1	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.30610312772567977	[69]	[152]	3	hSpCas9	negative selection	10620669
67722813	67722836	X	+	28162770	SKM1	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	-0.07178000715353261	[194]	[327]	0	hSpCas9	negative selection	10620670
67643308	67643331	X	+	28162770	SKM1	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	1.0039689022029454	[10]	[38]	8	hSpCas9	negative selection	10620671
67711457	67711480	X	+	28162770	SKM1	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.2516859732652507	[65]	[97]	-2	hSpCas9	negative selection	10620672
67722926	67722949	X	-	28162770	PL21	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.4185301052682717	[721]	[419]	3	hSpCas9	negative selection	10790029
67711658	67711681	X	+	28162770	PL21	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.030214613047007677	[107]	[47]	0	hSpCas9	negative selection	10790030
67711430	67711453	X	+	28162770	PL21	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	-0.2786945353704927	[130]	[46]	-2	hSpCas9	negative selection	10790031
67686105	67686128	X	+	28162770	PL21	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.6911259670014624	[221]	[155]	6	hSpCas9	negative selection	10790032
67717476	67717499	X	+	28162770	PL21	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.12766997615687503	[346]	[164]	1	hSpCas9	negative selection	10790033
67717533	67717556	X	+	28162770	PL21	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	-0.3417541643399502	[98]	[33]	-2	hSpCas9	negative selection	10790034
67721832	67721855	X	+	28162770	PL21	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.3927846924317159	[279]	[159]	3	hSpCas9	negative selection	10790035
67722813	67722836	X	+	28162770	PL21	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.7820744225129084	[635]	[475]	6	hSpCas9	negative selection	10790036
67643308	67643331	X	+	28162770	PL21	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.8154757642539949	[46]	[35]	7	hSpCas9	negative selection	10790037
67711457	67711480	X	+	28162770	PL21	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.10242315553111125	[258]	[104]	0	hSpCas9	negative selection	10790038
67722926	67722949	X	-	28162770	P31FUJ	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.17961554647638445	[688]	[916]	2	hSpCas9	negative selection	10959395
67711658	67711681	X	+	28162770	P31FUJ	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	-0.03754591301544474	[137]	[157]	0	hSpCas9	negative selection	10959396
67711430	67711453	X	+	28162770	P31FUJ	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.6940313830236498	[90]	[172]	7	hSpCas9	negative selection	10959397
67686105	67686128	X	+	28162770	P31FUJ	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.12819545515157588	[203]	[261]	1	hSpCas9	negative selection	10959398
67717476	67717499	X	+	28162770	P31FUJ	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.19718563633043662	[287]	[387]	2	hSpCas9	negative selection	10959399
67717533	67717556	X	+	28162770	P31FUJ	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.006385459465047427	[121]	[143]	0	hSpCas9	negative selection	10959400
67721832	67721855	X	+	28162770	P31FUJ	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.9807497294281917	[303]	[704]	9	hSpCas9	negative selection	10959401
67722813	67722836	X	+	28162770	P31FUJ	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.40774705804509237	[890]	[1388]	4	hSpCas9	negative selection	10959402
67643308	67643331	X	+	28162770	P31FUJ	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	1.0634392468093343	[67]	[166]	9	hSpCas9	negative selection	10959403
67711457	67711480	X	+	28162770	P31FUJ	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	0.30163554676397053	[338]	[490]	3	hSpCas9	negative selection	10959404
67722926	67722949	X	-	28162770	OCIAML5	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	1.0633556583656383	[280]	[1059]	8	hSpCas9	negative selection	11128761
67711658	67711681	X	+	28162770	OCIAML5	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.3796637150517872	[65]	[154]	3	hSpCas9	negative selection	11128762
67711430	67711453	X	+	28162770	OCIAML5	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	1.3059352632024959	[53]	[240]	9	hSpCas9	negative selection	11128763
67686105	67686128	X	+	28162770	OCIAML5	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.9177051683854509	[99]	[340]	7	hSpCas9	negative selection	11128764
67717476	67717499	X	+	28162770	OCIAML5	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.5888993934053728	[192]	[523]	5	hSpCas9	negative selection	11128765
67717533	67717556	X	+	28162770	OCIAML5	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	-0.3811758368516356	[56]	[78]	-3	hSpCas9	negative selection	11128766
67721832	67721855	X	+	28162770	OCIAML5	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.07966415311897457	[237]	[453]	0	hSpCas9	negative selection	11128767
67722813	67722836	X	+	28162770	OCIAML5	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.36039554463729084	[478]	[1109]	3	hSpCas9	negative selection	11128768
67643308	67643331	X	+	28162770	OCIAML5	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	-0.22552496639144137	[56]	[87]	-2	hSpCas9	negative selection	11128769
67711457	67711480	X	+	28162770	OCIAML5	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.35576168996323754	[150]	[212]	-3	hSpCas9	negative selection	11128770
67722926	67722949	X	-	28162770	EOL1	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.4571215905224628	[1130]	[817]	4	hSpCas9	negative selection	11298127
67711658	67711681	X	+	28162770	EOL1	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.9899708465685833	[193]	[202]	8	hSpCas9	negative selection	11298128
67711430	67711453	X	+	28162770	EOL1	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	-0.23895096071234478	[167]	[74]	-2	hSpCas9	negative selection	11298129
67686105	67686128	X	+	28162770	EOL1	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.5696849529750483	[492]	[174]	-4	hSpCas9	negative selection	11298130
67717476	67717499	X	+	28162770	EOL1	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.7757471101638286	[499]	[450]	6	hSpCas9	negative selection	11298131
67717533	67717556	X	+	28162770	EOL1	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	-0.0933741364267277	[242]	[119]	0	hSpCas9	negative selection	11298132
67721832	67721855	X	+	28162770	EOL1	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.7442808259067633	[314]	[277]	6	hSpCas9	negative selection	11298133
67722813	67722836	X	+	28162770	EOL1	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.7197585067726942	[800]	[694]	6	hSpCas9	negative selection	11298134
67643308	67643331	X	+	28162770	EOL1	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	1.1924809768171676	[48]	[58]	8	hSpCas9	negative selection	11298135
67711457	67711480	X	+	28162770	EOL1	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.8436365532063917	[326]	[95]	-5	hSpCas9	negative selection	11298136
67722926	67722949	X	-	28162770	MOLM13	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	1.06414189548496	[890]	[1346]	7	hSpCas9	negative selection	11467493
67711658	67711681	X	+	28162770	MOLM13	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	-0.9257744669416981	[133]	[50]	-5	hSpCas9	negative selection	11467494
67711430	67711453	X	+	28162770	MOLM13	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.7573959987395635	[179]	[219]	6	hSpCas9	negative selection	11467495
67686105	67686128	X	+	28162770	MOLM13	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.19785577389262354	[302]	[190]	-1	hSpCas9	negative selection	11467496
67717476	67717499	X	+	28162770	MOLM13	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.6745431554388761	[473]	[546]	5	hSpCas9	negative selection	11467497
67717533	67717556	X	+	28162770	MOLM13	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	1.0840465038693292	[121]	[186]	8	hSpCas9	negative selection	11467498
67721832	67721855	X	+	28162770	MOLM13	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.6346139806963944	[350]	[393]	5	hSpCas9	negative selection	11467499
67722813	67722836	X	+	28162770	MOLM13	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.5433849134730042	[1060]	[1117]	4	hSpCas9	negative selection	11467500
67643308	67643331	X	+	28162770	MOLM13	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	-0.4184538366598538	[60]	[32]	-2	hSpCas9	negative selection	11467501
67711457	67711480	X	+	28162770	MOLM13	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.5240282721575624	[355]	[178]	-3	hSpCas9	negative selection	11467502
67722926	67722949	X	-	28162770	HEL	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.5995669978587834	[847]	[822]	5	hSpCas9	negative selection	11636859
67711658	67711681	X	+	28162770	HEL	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.9381947155265282	[109]	[134]	7	hSpCas9	negative selection	11636860
67711430	67711453	X	+	28162770	HEL	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.47968055004631127	[130]	[116]	4	hSpCas9	negative selection	11636861
67686105	67686128	X	+	28162770	HEL	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	1.5315035907059251	[282]	[523]	9	hSpCas9	negative selection	11636862
67717476	67717499	X	+	28162770	HEL	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.9619422895511838	[423]	[528]	8	hSpCas9	negative selection	11636863
67717533	67717556	X	+	28162770	HEL	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.33461653663802504	[129]	[104]	2	hSpCas9	negative selection	11636864
67721832	67721855	X	+	28162770	HEL	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	-0.6697289336379393	[379]	[152]	-4	hSpCas9	negative selection	11636865
67722813	67722836	X	+	28162770	HEL	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	1.2444995838846458	[739]	[1122]	9	hSpCas9	negative selection	11636866
67643308	67643331	X	+	28162770	HEL	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.20216624061437583	[56]	[41]	1	hSpCas9	negative selection	11636867
67711457	67711480	X	+	28162770	HEL	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	0.4901610741219413	[278]	[250]	4	hSpCas9	negative selection	11636868
67722926	67722949	X	-	28162770	MV411	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.6660593874106582	[602]	[805]	6	hSpCas9	negative selection	11806225
67711658	67711681	X	+	28162770	MV411	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.3073090067601741	[117]	[122]	2	hSpCas9	negative selection	11806226
67711430	67711453	X	+	28162770	MV411	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.5953608542030819	[87]	[111]	5	hSpCas9	negative selection	11806227
67686105	67686128	X	+	28162770	MV411	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.36194943190648105	[229]	[248]	3	hSpCas9	negative selection	11806228
67717476	67717499	X	+	28162770	MV411	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.890115549360219	[293]	[458]	7	hSpCas9	negative selection	11806229
67717533	67717556	X	+	28162770	MV411	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	1.261512735994498	[101]	[205]	9	hSpCas9	negative selection	11806230
67721832	67721855	X	+	28162770	MV411	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	-0.4420555334096875	[278]	[172]	-3	hSpCas9	negative selection	11806231
67722813	67722836	X	+	28162770	MV411	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.9289080323572778	[582]	[934]	8	hSpCas9	negative selection	11806232
67643308	67643331	X	+	28162770	MV411	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.6988168971253392	[48]	[66]	6	hSpCas9	negative selection	11806233
67711457	67711480	X	+	28162770	MV411	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.7852286381375467	[267]	[130]	-5	hSpCas9	negative selection	11806234
67722926	67722949	X	-	28162770	MONOMAC1	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.2786965839068438	[383]	[533]	3	hSpCas9	negative selection	11975591
67711658	67711681	X	+	28162770	MONOMAC1	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.05608208990915731	[72]	[86]	0	hSpCas9	negative selection	11975592
67711430	67711453	X	+	28162770	MONOMAC1	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.6289337531653975	[87]	[155]	6	hSpCas9	negative selection	11975593
67686105	67686128	X	+	28162770	MONOMAC1	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.6103180749980504	[123]	[216]	6	hSpCas9	negative selection	11975594
67717476	67717499	X	+	28162770	MONOMAC1	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	1.3805461232960048	[195]	[584]	9	hSpCas9	negative selection	11975595
67717533	67717556	X	+	28162770	MONOMAC1	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	0.987995046772967	[94]	[215]	8	hSpCas9	negative selection	11975596
67721832	67721855	X	+	28162770	MONOMAC1	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	0.6663901000650022	[154]	[281]	6	hSpCas9	negative selection	11975597
67722813	67722836	X	+	28162770	MONOMAC1	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.6824132204584303	[367]	[676]	6	hSpCas9	negative selection	11975598
67643308	67643331	X	+	28162770	MONOMAC1	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.44681934271517076	[31]	[49]	4	hSpCas9	negative selection	11975599
67711457	67711480	X	+	28162770	MONOMAC1	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.047011403054946055	[145]	[161]	0	hSpCas9	negative selection	11975600
67722926	67722949	X	-	28162770	OCIAML2	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.27238020566512144	[130]	[876]	2	hSpCas9	negative selection	12144957
67711658	67711681	X	+	28162770	OCIAML2	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.14604153520633334	[14]	[91]	1	hSpCas9	negative selection	12144958
67711430	67711453	X	+	28162770	OCIAML2	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	0.18758165750963374	[15]	[100]	1	hSpCas9	negative selection	12144959
67686105	67686128	X	+	28162770	OCIAML2	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	0.2510690122707345	[56]	[375]	2	hSpCas9	negative selection	12144960
67717476	67717499	X	+	28162770	OCIAML2	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	0.27105817916644814	[60]	[407]	2	hSpCas9	negative selection	12144961
67717533	67717556	X	+	28162770	OCIAML2	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	1.215870701941057	[7]	[102]	9	hSpCas9	negative selection	12144962
67721832	67721855	X	+	28162770	OCIAML2	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	1.4147276088167162	[35]	[531]	9	hSpCas9	negative selection	12144963
67722813	67722836	X	+	28162770	OCIAML2	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.39653449205074653	[107]	[787]	4	hSpCas9	negative selection	12144964
67643308	67643331	X	+	28162770	OCIAML2	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.09415479354136447	[11]	[70]	0	hSpCas9	negative selection	12144965
67711457	67711480	X	+	28162770	OCIAML2	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	0.6274022577183657	[31]	[273]	6	hSpCas9	negative selection	12144966
67722926	67722949	X	-	28162770	OCIAML3	viability	GAAGCGTCTTGAGCAGGATGTGG	AR	ENSG00000169083	0.9062126601557576	[148]	[842]	7	hSpCas9	negative selection	12314323
67711658	67711681	X	+	28162770	OCIAML3	viability	ACACGTGGTCAAGTGGGCCAAGG	AR	ENSG00000169083	0.04540264441936932	[51]	[161]	0	hSpCas9	negative selection	12314324
67711430	67711453	X	+	28162770	OCIAML3	viability	GAAACTACAGGAGGAAGGAGAGG	AR	ENSG00000169083	-0.435309894305105	[42]	[95]	-3	hSpCas9	negative selection	12314325
67686105	67686128	X	+	28162770	OCIAML3	viability	GAAGCAGGGATGACTCTGGGAGG	AR	ENSG00000169083	-0.6828169072820192	[66]	[125]	-5	hSpCas9	negative selection	12314326
67717476	67717499	X	+	28162770	OCIAML3	viability	AGGCTTCCGCAACTTACACGTGG	AR	ENSG00000169083	-0.2839049808335904	[97]	[242]	-2	hSpCas9	negative selection	12314327
67717533	67717556	X	+	28162770	OCIAML3	viability	GGGGCTCATGGTGTTTGCCATGG	AR	ENSG00000169083	-0.558383730593442	[39]	[81]	-4	hSpCas9	negative selection	12314328
67721832	67721855	X	+	28162770	OCIAML3	viability	GGTACCGCATGCACAAGTCCCGG	AR	ENSG00000169083	-0.5845473110750967	[75]	[152]	-4	hSpCas9	negative selection	12314329
67722813	67722836	X	+	28162770	OCIAML3	viability	TCATCCCACATCAGTTCCAGTGG	AR	ENSG00000169083	0.04687084965066579	[193]	[604]	0	hSpCas9	negative selection	12314330
67643308	67643331	X	+	28162770	OCIAML3	viability	CAGAAGACCTGCCTGATCTGTGG	AR	ENSG00000169083	0.24249362739295743	[13]	[49]	2	hSpCas9	negative selection	12314331
67711457	67711480	X	+	28162770	OCIAML3	viability	CAGCACCACCAGCCCCACTGAGG	AR	ENSG00000169083	-0.39546196094208297	[60]	[139]	-3	hSpCas9	negative selection	12314332