Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 431705
• Symbol: ASTL
• Description: astacin like metalloendopeptidase

DataSource: http://genomecrispr.dkfz.de/#!/results/ASTL

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
96133510	96133533	2	+	26472758	Jiyoye	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.9419741821165133	[213]	[83]	-6	hSpCas9	negative selection	11360
96137661	96137684	2	+	26472758	Jiyoye	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	-0.7703628040463142	[94]	[41]	-5	hSpCas9	negative selection	11361
96137588	96137611	2	+	26472758	Jiyoye	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.7442103687834442	[189]	[239]	5	hSpCas9	negative selection	11362
96137574	96137597	2	-	26472758	Jiyoye	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.16540339475945026	[173]	[116]	-1	hSpCas9	negative selection	11363
96134032	96134055	2	+	26472758	Jiyoye	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-0.10739779132388483	[9]	[6]	-1	hSpCas9	negative selection	11364
96133992	96134015	2	-	26472758	Jiyoye	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	0.4071753815058736	[14]	[14]	3	hSpCas9	negative selection	11365
96129908	96129931	2	+	26472758	Jiyoye	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.14963607890113373	[202]	[137]	-1	hSpCas9	negative selection	11366
96129875	96129898	2	-	26472758	Jiyoye	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.07533181775342834	[72]	[57]	0	hSpCas9	negative selection	11367
96129837	96129860	2	-	26472758	Jiyoye	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.7052567344388679	[60]	[74]	5	hSpCas9	negative selection	11368
96138390	96138413	2	+	26472758	Jiyoye	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.28431863372034005	[48]	[44]	2	hSpCas9	negative selection	11369
96133510	96133533	2	+	26472758	KBM7	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.10441937729451256	[707,607]	[287,285]	-1	hSpCas9	negative selection	202478
96137661	96137684	2	+	26472758	KBM7	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.3014883621966821	[412,366]	[211,237]	3	hSpCas9	negative selection	202479
96137588	96137611	2	+	26472758	KBM7	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.15324155452315646	[1452,679]	[705,390]	1	hSpCas9	negative selection	202480
96137574	96137597	2	-	26472758	KBM7	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.4169596278398817	[684,718]	[219,274]	-4	hSpCas9	negative selection	202481
96134032	96134055	2	+	26472758	KBM7	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-0.6093981857399036	[47,25]	[8,12]	-5	hSpCas9	negative selection	202482
96133992	96134015	2	-	26472758	KBM7	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	0.22111842046683705	[86,74]	[57,31]	2	hSpCas9	negative selection	202483
96129908	96129931	2	+	26472758	KBM7	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.24402385168646698	[607,480]	[299,301]	2	hSpCas9	negative selection	202484
96129875	96129898	2	-	26472758	KBM7	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.3120600159900005	[301,297]	[206,147]	3	hSpCas9	negative selection	202485
96129837	96129860	2	-	26472758	KBM7	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.8407687471386813	[339,239]	[295,191]	8	hSpCas9	negative selection	202486
96138390	96138413	2	+	26472758	KBM7	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.6083870671504781	[243,161]	[157,129]	6	hSpCas9	negative selection	202487
96133510	96133533	2	+	26472758	Raji	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.4578157105261267	[289]	[48]	-4	hSpCas9	negative selection	393596
96137661	96137684	2	+	26472758	Raji	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	-0.717044900042946	[254]	[35]	-5	hSpCas9	negative selection	393597
96137588	96137611	2	+	26472758	Raji	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.3946654874540705	[471]	[143]	4	hSpCas9	negative selection	393598
96137574	96137597	2	-	26472758	Raji	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.3016301762774741	[238]	[44]	-3	hSpCas9	negative selection	393599
96134032	96134055	2	+	26472758	Raji	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-1.8622428155828823	[46]	[2]	-8	hSpCas9	negative selection	393600
96133992	96134015	2	-	26472758	Raji	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	1.6923460360947558	[7]	[5]	9	hSpCas9	negative selection	393601
96129908	96129931	2	+	26472758	Raji	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.6528176719081182	[221]	[80]	6	hSpCas9	negative selection	393602
96129875	96129898	2	-	26472758	Raji	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.2849338874051607	[125]	[23]	-2	hSpCas9	negative selection	393603
96129837	96129860	2	-	26472758	Raji	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.24678659203901598	[137]	[37]	2	hSpCas9	negative selection	393604
96138390	96138413	2	+	26472758	Raji	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.07496205768122222	[89]	[21]	0	hSpCas9	negative selection	393605
96133510	96133533	2	+	26472758	K562	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-3.002375037160136	[635]	[66]	-8	hSpCas9	negative selection	584714
96137661	96137684	2	+	26472758	K562	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.23988906918593284	[318]	[317]	1	hSpCas9	negative selection	584715
96137588	96137611	2	+	26472758	K562	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.16988699627797132	[656]	[492]	-1	hSpCas9	negative selection	584716
96137574	96137597	2	-	26472758	K562	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.05757388500909588	[460]	[404]	0	hSpCas9	negative selection	584717
96134032	96134055	2	+	26472758	K562	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-0.3030690676360459	[18]	[12]	-2	hSpCas9	negative selection	584718
96133992	96134015	2	-	26472758	K562	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	2.071269825349848	[83]	[297]	9	hSpCas9	negative selection	584719
96129908	96129931	2	+	26472758	K562	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.14750153198774357	[453]	[345]	-1	hSpCas9	negative selection	584720
96129875	96129898	2	-	26472758	K562	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.6789599907306405	[274]	[144]	-4	hSpCas9	negative selection	584721
96129837	96129860	2	-	26472758	K562	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	-0.46607465513856816	[197]	[120]	-3	hSpCas9	negative selection	584722
96138390	96138413	2	+	26472758	K562	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.35133393158295867	[155]	[167]	2	hSpCas9	negative selection	584723
96129875	96129898	2	-	26627737	DLD1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.479750648049148	[156]	[43,24,35]	-5	hSpCas9	negative selection	813122
96132654	96132677	2	+	26627737	DLD1	viability	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.6739775966706868	[245]	[128,99,135]	6	hSpCas9	negative selection	813123
96133469	96133492	2	+	26627737	DLD1	viability	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.5423034086070566	[219]	[62,65,17]	-5	hSpCas9	negative selection	813124
96133996	96134019	2	+	26627737	DLD1	viability	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.10848550997521134	[2057]	[503,882,439]	-1	hSpCas9	negative selection	813125
96135365	96135388	2	-	26627737	DLD1	viability	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-2.4723917394583035	[425]	[6,13,46]	-9	hSpCas9	negative selection	813126
96137682	96137705	2	+	26627737	DLD1	viability	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.9383744303555689	[211]	[99,147,132]	8	hSpCas9	negative selection	813127
96129875	96129898	2	-	26627737	GBM cells	viability after 5 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.30753700258174055	[44]	[17,20]	-5	hSpCas9	negative selection	895437
96132654	96132677	2	+	26627737	GBM cells	viability after 5 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.8164517146937125	[71]	[54,80]	9	hSpCas9	negative selection	895438
96133469	96133492	2	+	26627737	GBM cells	viability after 5 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.7140630020050673	[77]	[26,23]	-8	hSpCas9	negative selection	895439
96133996	96134019	2	+	26627737	GBM cells	viability after 5 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.05522418833074805	[773]	[399,398]	-1	hSpCas9	negative selection	895440
96135365	96135388	2	-	26627737	GBM cells	viability after 5 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.6574794736386997	[174]	[82,35]	-8	hSpCas9	negative selection	895441
96137682	96137705	2	+	26627737	GBM cells	viability after 5 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	1.0915589528280814	[69]	[71,87]	9	hSpCas9	negative selection	895442
96129875	96129898	2	-	26627737	GBM cells	viability after 13 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.4963142089631223	[44]	[13,19]	-5	hSpCas9	negative selection	977752
96132654	96132677	2	+	26627737	GBM cells	viability after 13 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.5953604631524607	[71]	[106,19]	7	hSpCas9	negative selection	977753
96133469	96133492	2	+	26627737	GBM cells	viability after 13 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.3324678329301054	[77]	[10,51]	-4	hSpCas9	negative selection	977754
96133996	96134019	2	+	26627737	GBM cells	viability after 13 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.1510305925678539	[773]	[466,305]	-2	hSpCas9	negative selection	977755
96135365	96135388	2	-	26627737	GBM cells	viability after 13 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.29257300714585577	[174]	[87,68]	-3	hSpCas9	negative selection	977756
96137682	96137705	2	+	26627737	GBM cells	viability after 13 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.576936506785289	[69]	[54,57]	7	hSpCas9	negative selection	977757
96129875	96129898	2	-	26627737	GBM cells	viability after 21 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-1.6116197967140162	[44]	[7,7]	-8	hSpCas9	negative selection	1060067
96132654	96132677	2	+	26627737	GBM cells	viability after 21 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.8709020676867025	[71]	[23,18]	-6	hSpCas9	negative selection	1060068
96133469	96133492	2	+	26627737	GBM cells	viability after 21 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-1.5538363001283833	[77]	[15,12]	-8	hSpCas9	negative selection	1060069
96133996	96134019	2	+	26627737	GBM cells	viability after 21 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.44045269873274173	[773]	[312,306]	-4	hSpCas9	negative selection	1060070
96135365	96135388	2	-	26627737	GBM cells	viability after 21 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.5436861205489305	[174]	[59,69]	-5	hSpCas9	negative selection	1060071
96137682	96137705	2	+	26627737	GBM cells	viability after 21 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.3109858422463945	[69]	[42,50]	3	hSpCas9	negative selection	1060072
96129875	96129898	2	-	26627737	RPE1	viability after 9 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.23548760541799219	[116]	[24,38]	-2	hSpCas9	negative selection	1142382
96132654	96132677	2	+	26627737	RPE1	viability after 9 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.5417798098892317	[420]	[159,232]	3	hSpCas9	negative selection	1142383
96133469	96133492	2	+	26627737	RPE1	viability after 9 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-1.5441364851646646	[618]	[41,97]	-8	hSpCas9	negative selection	1142384
96133996	96134019	2	+	26627737	RPE1	viability after 9 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.6323761770820564	[3180]	[803,433]	-4	hSpCas9	negative selection	1142385
96135365	96135388	2	-	26627737	RPE1	viability after 9 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.0932292688573485	[561]	[126,265]	0	hSpCas9	negative selection	1142386
96137682	96137705	2	+	26627737	RPE1	viability after 9 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.4722681469083485	[398]	[79,102]	-3	hSpCas9	negative selection	1142387
96129875	96129898	2	-	26627737	RPE1	viability after 12 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.547030270183305	[116]	[21,20]	-4	hSpCas9	negative selection	1224697
96132654	96132677	2	+	26627737	RPE1	viability after 12 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.5435802640934931	[420]	[97,55]	-4	hSpCas9	negative selection	1224698
96133469	96133492	2	+	26627737	RPE1	viability after 12 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-6.031233773519696	[618]	[3,0]	-9	hSpCas9	negative selection	1224699
96133996	96134019	2	+	26627737	RPE1	viability after 12 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.6335440040535671	[3180]	[563,536]	-4	hSpCas9	negative selection	1224700
96135365	96135388	2	-	26627737	RPE1	viability after 12 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.24388801774816718	[561]	[154,203]	1	hSpCas9	negative selection	1224701
96137682	96137705	2	+	26627737	RPE1	viability after 12 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.06606161943657018	[398]	[149,51]	0	hSpCas9	negative selection	1224702
96129875	96129898	2	-	26627737	RPE1	viability after 15 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-1.501407236678081	[116]	[0,21]	-7	hSpCas9	negative selection	1307012
96132654	96132677	2	+	26627737	RPE1	viability after 15 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.652473512330224	[420]	[88,62]	-4	hSpCas9	negative selection	1307013
96133469	96133492	2	+	26627737	RPE1	viability after 15 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-2.804930206404059	[618]	[49,0]	-9	hSpCas9	negative selection	1307014
96133996	96134019	2	+	26627737	RPE1	viability after 15 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.5856330802966079	[3180]	[733,469]	-4	hSpCas9	negative selection	1307015
96135365	96135388	2	-	26627737	RPE1	viability after 15 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.4180791293724065	[561]	[119,117]	-3	hSpCas9	negative selection	1307016
96137682	96137705	2	+	26627737	RPE1	viability after 15 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.10211950726746621	[398]	[140,101]	0	hSpCas9	negative selection	1307017
96129875	96129898	2	-	26627737	RPE1	viability after 18 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.36798974679345475	[116]	[47,32]	2	hSpCas9	negative selection	1389327
96132654	96132677	2	+	26627737	RPE1	viability after 18 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.1910056442319915	[420]	[143,51]	-1	hSpCas9	negative selection	1389328
96133469	96133492	2	+	26627737	RPE1	viability after 18 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-3.1300950708993676	[618]	[35,0]	-9	hSpCas9	negative selection	1389329
96133996	96134019	2	+	26627737	RPE1	viability after 18 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-1.0321487980665807	[3180]	[514,317]	-6	hSpCas9	negative selection	1389330
96135365	96135388	2	-	26627737	RPE1	viability after 18 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.4413441159217404	[561]	[145,269]	3	hSpCas9	negative selection	1389331
96137682	96137705	2	+	26627737	RPE1	viability after 18 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.4747610904833084	[398]	[76,77]	-3	hSpCas9	negative selection	1389332
96129875	96129898	2	-	26627737	HeLa	viability after 8 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.7967313447493831	[15]	[0,0,8]	-7	hSpCas9	negative selection	1471642
96132654	96132677	2	+	26627737	HeLa	viability after 8 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.4263618143461386	[260]	[141,167,145]	4	hSpCas9	negative selection	1471643
96133469	96133492	2	+	26627737	HeLa	viability after 8 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-1.8623703239357823	[389]	[86,1,58]	-9	hSpCas9	negative selection	1471644
96133996	96134019	2	+	26627737	HeLa	viability after 8 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.3715745222235016	[1187]	[925,734,419]	3	hSpCas9	negative selection	1471645
96135365	96135388	2	-	26627737	HeLa	viability after 8 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.7144311161753705	[658]	[190,36,58]	-9	hSpCas9	negative selection	1471646
96137682	96137705	2	+	26627737	HeLa	viability after 8 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.3258300736536762	[212]	[89,129,9]	-3	hSpCas9	negative selection	1471647
96129875	96129898	2	-	26627737	HeLa	viability after 12 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	2.1142935941202787	[15]	[0,19,64]	9	hSpCas9	negative selection	1553957
96132654	96132677	2	+	26627737	HeLa	viability after 12 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.660533642114063	[260]	[11,68,121]	-5	hSpCas9	negative selection	1553958
96133469	96133492	2	+	26627737	HeLa	viability after 12 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-1.113255080449757	[389]	[118,15,95]	-7	hSpCas9	negative selection	1553959
96133996	96134019	2	+	26627737	HeLa	viability after 12 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.21926473347353959	[1187]	[920,512,296]	2	hSpCas9	negative selection	1553960
96135365	96135388	2	-	26627737	HeLa	viability after 12 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.3054634856527307	[658]	[50,136,137]	-8	hSpCas9	negative selection	1553961
96137682	96137705	2	+	26627737	HeLa	viability after 12 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.12281118143750047	[212]	[78,56,108]	-1	hSpCas9	negative selection	1553962
96129875	96129898	2	-	26627737	HeLa	viability after 15 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	2.7335267307590962	[15]	[7,59,63]	9	hSpCas9	negative selection	1636272
96132654	96132677	2	+	26627737	HeLa	viability after 15 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-1.318158113223587	[260]	[56,47,20]	-8	hSpCas9	negative selection	1636273
96133469	96133492	2	+	26627737	HeLa	viability after 15 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.4887400623931821	[389]	[99,0,248]	-4	hSpCas9	negative selection	1636274
96133996	96134019	2	+	26627737	HeLa	viability after 15 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.07870313619419278	[1187]	[420,535,413]	0	hSpCas9	negative selection	1636275
96135365	96135388	2	-	26627737	HeLa	viability after 15 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.6579002473246258	[658]	[95,96,59]	-8	hSpCas9	negative selection	1636276
96137682	96137705	2	+	26627737	HeLa	viability after 15 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-1.4549821212349685	[212]	[0,53,40]	-8	hSpCas9	negative selection	1636277
96129875	96129898	2	-	26627737	HeLa	viability after 18 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	2.7003978711761176	[15]	[3,48,63]	9	hSpCas9	negative selection	1718587
96132654	96132677	2	+	26627737	HeLa	viability after 18 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-1.3720890343267431	[260]	[34,39,20]	-8	hSpCas9	negative selection	1718588
96133469	96133492	2	+	26627737	HeLa	viability after 18 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.4689438286675298	[389]	[69,0,248]	-4	hSpCas9	negative selection	1718589
96133996	96134019	2	+	26627737	HeLa	viability after 18 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.11003029922192087	[1187]	[267,437,413]	-1	hSpCas9	negative selection	1718590
96135365	96135388	2	-	26627737	HeLa	viability after 18 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.6291185869623588	[658]	[71,74,59]	-8	hSpCas9	negative selection	1718591
96137682	96137705	2	+	26627737	HeLa	viability after 18 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-1.4606602340187096	[212]	[0,43,40]	-8	hSpCas9	negative selection	1718592
96129875	96129898	2	-	26627737	HCT116	viability after 6 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-2.9494772138899403	[118]	[4,0]	-9	hSpCas9	negative selection	1800902
96132654	96132677	2	+	26627737	HCT116	viability after 6 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	1.0077335131526286	[254]	[39,102]	5	hSpCas9	negative selection	1800903
96133469	96133492	2	+	26627737	HCT116	viability after 6 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.19655514513503514	[239]	[88,1]	-1	hSpCas9	negative selection	1800904
96133996	96134019	2	+	26627737	HCT116	viability after 6 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	1.1495257884476249	[1616]	[454,623]	6	hSpCas9	negative selection	1800905
96135365	96135388	2	-	26627737	HCT116	viability after 6 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.7243357301294235	[744]	[139,222]	4	hSpCas9	negative selection	1800906
96137682	96137705	2	+	26627737	HCT116	viability after 6 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	1.6271738111800864	[496]	[105,315]	8	hSpCas9	negative selection	1800907
96129875	96129898	2	-	26627737	HCT116	viability after 8 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	5.512627347537192	[0]	[47,12,14]	9	hSpCas9	negative selection	1883217
96132654	96132677	2	+	26627737	HCT116	viability after 8 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	2.5215970860240065	[59]	[273,103,192]	9	hSpCas9	negative selection	1883218
96133469	96133492	2	+	26627737	HCT116	viability after 8 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.8250289289031494	[247]	[66,67,95]	-7	hSpCas9	negative selection	1883219
96133996	96134019	2	+	26627737	HCT116	viability after 8 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.305302353988528	[901]	[633,524,682]	3	hSpCas9	negative selection	1883220
96135365	96135388	2	-	26627737	HCT116	viability after 8 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.5062162532872149	[285]	[84,102,143]	-6	hSpCas9	negative selection	1883221
96137682	96137705	2	+	26627737	HCT116	viability after 8 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.8669209071752088	[189]	[35,91,43]	-8	hSpCas9	negative selection	1883222
96129875	96129898	2	-	26627737	HCT116	viability after 9 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-3.907726871739581	[118]	[0,2]	-9	hSpCas9	negative selection	1965532
96132654	96132677	2	+	26627737	HCT116	viability after 9 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.5353279544483673	[254]	[70,27]	-4	hSpCas9	negative selection	1965533
96133469	96133492	2	+	26627737	HCT116	viability after 9 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	0.5233554703418384	[239]	[195,9]	4	hSpCas9	negative selection	1965534
96133996	96134019	2	+	26627737	HCT116	viability after 9 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.06744438968856303	[1616]	[495,417]	0	hSpCas9	negative selection	1965535
96135365	96135388	2	-	26627737	HCT116	viability after 9 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.1509120892936764	[744]	[83,93]	-7	hSpCas9	negative selection	1965536
96137682	96137705	2	+	26627737	HCT116	viability after 9 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.06045642145064961	[496]	[86,178]	0	hSpCas9	negative selection	1965537
96129875	96129898	2	-	26627737	HCT116	viability after 12 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	5.483095685030577	[0]	[13,8,47]	9	hSpCas9	negative selection	2047847
96132654	96132677	2	+	26627737	HCT116	viability after 12 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	1.9913548768605602	[59]	[133,192,49]	9	hSpCas9	negative selection	2047848
96133469	96133492	2	+	26627737	HCT116	viability after 12 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.25289304406383645	[247]	[105,91,129]	-3	hSpCas9	negative selection	2047849
96133996	96134019	2	+	26627737	HCT116	viability after 12 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.3133802692618084	[901]	[518,743,513]	3	hSpCas9	negative selection	2047850
96135365	96135388	2	-	26627737	HCT116	viability after 12 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.043489755728632	[285]	[88,99,28]	-8	hSpCas9	negative selection	2047851
96137682	96137705	2	+	26627737	HCT116	viability after 12 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.7129145226370036	[189]	[44,95,43]	-6	hSpCas9	negative selection	2047852
96129875	96129898	2	-	26627737	HCT116	viability after 15 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	3.8116004861026944	[0]	[13,9,0]	9	hSpCas9	negative selection	2130162
96132654	96132677	2	+	26627737	HCT116	viability after 15 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	2.2397970194856773	[59]	[244,150,102]	9	hSpCas9	negative selection	2130163
96133469	96133492	2	+	26627737	HCT116	viability after 15 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.5185689607229751	[247]	[97,92,106]	-5	hSpCas9	negative selection	2130164
96133996	96134019	2	+	26627737	HCT116	viability after 15 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.33914123405874563	[901]	[633,567,759]	3	hSpCas9	negative selection	2130165
96135365	96135388	2	-	26627737	HCT116	viability after 15 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.8584454478010567	[285]	[88,126,55]	-7	hSpCas9	negative selection	2130166
96137682	96137705	2	+	26627737	HCT116	viability after 15 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.11538068776170252	[189]	[101,162,87]	1	hSpCas9	negative selection	2130167
96129875	96129898	2	-	26627737	HCT116	viability after 18 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	5.763892966491053	[0]	[62,0,15]	9	hSpCas9	negative selection	2212477
96132654	96132677	2	+	26627737	HCT116	viability after 18 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	1.275014088940365	[59]	[65,76,66]	8	hSpCas9	negative selection	2212478
96133469	96133492	2	+	26627737	HCT116	viability after 18 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	0.034421514600370545	[247]	[130,173,56]	0	hSpCas9	negative selection	2212479
96133996	96134019	2	+	26627737	HCT116	viability after 18 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.4969687399456806	[901]	[563,509,786]	4	hSpCas9	negative selection	2212480
96135365	96135388	2	-	26627737	HCT116	viability after 18 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.7668155645587088	[285]	[167,0,79]	-6	hSpCas9	negative selection	2212481
96137682	96137705	2	+	26627737	HCT116	viability after 18 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.19508171982402267	[189]	[48,141,43]	-2	hSpCas9	negative selection	2212482
96133998	96134021	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.07378439566723416	[3,3]	[3,3]	1	hSpCas9	positive selection	2972058
96132644	96132667	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	-0.3197057061398906	[4,4]	[3,2]	-4	hSpCas9	positive selection	2972059
96135336	96135359	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	0.22620498157661623	[2,3]	[3,3]	5	hSpCas9	positive selection	2972060
96135350	96135373	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	-0.04786145240045911	[2,2]	[3,1]	0	hSpCas9	positive selection	2972061
96133998	96134021	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.3595956444487104	[3,3]	[4,3]	6	hSpCas9	positive selection	3039916
96132644	96132667	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	-0.22632737933294717	[4,4]	[2,2]	-3	hSpCas9	positive selection	3039917
96135336	96135359	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	-0.2317025527325399	[2,2]	[2,1]	-3	hSpCas9	positive selection	3039918
96135350	96135373	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	0.5695516151090133	[2,2]	[3,2]	8	hSpCas9	positive selection	3039919
96135368	96135391		-	24336571	A375	resistance to PLX after 7 days	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.104718718982372	[7,7]	[8,8]	3	hSpCas9	positive selection	3134045
96137568	96137591		+	24336571	A375	resistance to PLX after 7 days	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.1269492386368778	[30,28]	[29,24]	-4	hSpCas9	positive selection	3134055
96135356	96135379		+	24336571	A375	resistance to PLX after 7 days	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	0.5212825217771094	[3,4]	[6,6]	9	hSpCas9	positive selection	3134066
96135401	96135424		-	24336571	A375	resistance to PLX after 7 days	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	-0.07478153637245644	[1,2]	[1,1]	-2	hSpCas9	positive selection	3134074
96135368	96135391		-	24336571	A375	resistance to PLX after 14 days	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.9161937556493432	[13,7]	[2,1]	-9	hSpCas9	positive selection	3191838
96137568	96137591		+	24336571	A375	resistance to PLX after 14 days	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.1329293332046535	[32,20]	[11,14]	1	hSpCas9	positive selection	3191848
96135356	96135379		+	24336571	A375	resistance to PLX after 14 days	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	0.6754203097315641	[4,3]	[2,3]	6	hSpCas9	positive selection	3191859
96135401	96135424		-	24336571	A375	resistance to PLX after 14 days	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	0.8881179138926127	[2,1]	[1,1]	7	hSpCas9	positive selection	3191867
96135368	96135391		-	24336571	A375	viability after 7 days	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.31635444472747354	[6]	[7,7]	5	hSpCas9	negative selection	3249631
96137568	96137591		+	24336571	A375	viability after 7 days	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.35305391871161274	[24]	[30,28]	5	hSpCas9	negative selection	3249641
96135356	96135379		+	24336571	A375	viability after 7 days	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	-0.7195913079242306	[8]	[3,4]	-8	hSpCas9	negative selection	3249652
96135401	96135424		-	24336571	A375	viability after 7 days	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	0.10873340364772943	[1]	[1,2]	1	hSpCas9	negative selection	3249660
96135368	96135391		-	24336571	A375	viability after 14 days	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.7349110052828576	[6]	[13,7]	8	hSpCas9	negative selection	3307424
96137568	96137591		+	24336571	A375	viability after 14 days	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.23464648904316243	[24]	[32,20]	3	hSpCas9	negative selection	3307434
96135356	96135379		+	24336571	A375	viability after 14 days	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	-0.8117389431534221	[8]	[4,3]	-7	hSpCas9	negative selection	3307445
96135401	96135424		-	24336571	A375	viability after 14 days	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	-0.05166748142567634	[1]	[2,1]	0	hSpCas9	negative selection	3307453
96133478	96133501	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.8003969759931505	[269,256]	[0,4]	4	hSpCas9	positive selection	3337838
96137568	96137591	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.3163952212185342	[191,188]	[0,0]	-2	hSpCas9	positive selection	3337839
96133954	96133977	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	4.350932972309017	[751,754]	[3,196]	9	hSpCas9	positive selection	3337840
96133498	96133521	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3357089
96135368	96135391	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.9906013019977503	[303,303]	[0,0]	-6	hSpCas9	positive selection	3357090
96133995	96134018	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3357091
96133997	96134020	2	+	26780180	HT29	viability (Avana library 4 designs)	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	1.92616555527841	[]	[]	7	hSpCas9	negative selection	3408196
96132644	96132667	2	-	26780180	HT29	viability (Avana library 4 designs)	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	0.635779135166574	[]	[]	2	hSpCas9	negative selection	3408197
96135335	96135358	2	+	26780180	HT29	viability (Avana library 4 designs)	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	1.60797071190071	[]	[]	6	hSpCas9	negative selection	3408198
96135350	96135373	2	-	26780180	HT29	viability (Avana library 4 designs)	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	1.84909771920875	[]	[]	7	hSpCas9	negative selection	3408199
96132644	96132667	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	4.86738773283718	[]	[]	8	hSpCas9	negative selection	3481618
96133997	96134020	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.136319948624821	[]	[]	0	hSpCas9	negative selection	3481619
96135350	96135373	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	4.43906442511396	[]	[]	7	hSpCas9	negative selection	3481620
96135335	96135358	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	4.60063223407325	[]	[]	7	hSpCas9	negative selection	3481621
96132627	96132650	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCATGAAGGACAATGCCCCGG	ASTL	ENSG00000188886	2.00434873392755	[]	[]	3	hSpCas9	negative selection	3481622
96132589	96132612	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTGGCACGAGCACACGCGG	ASTL	ENSG00000188886	6.3955736344839	[]	[]	9	hSpCas9	negative selection	3481623
96132644	96132667	2	-	26780180	A375	viability (Avana lentiGuide)	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	-2.35799227913274	[]	[]	-4	hSpCas9	negative selection	3590277
96133997	96134020	2	+	26780180	A375	viability (Avana lentiGuide)	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-4.18620980242432	[]	[]	-7	hSpCas9	negative selection	3590278
96135350	96135373	2	-	26780180	A375	viability (Avana lentiGuide)	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	-0.0392887523865433	[]	[]	0	hSpCas9	negative selection	3590279
96135335	96135358	2	+	26780180	A375	viability (Avana lentiGuide)	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	18.6414605498999	[]	[]	8	hSpCas9	negative selection	3590280
96132627	96132650	2	+	26780180	A375	viability (Avana lentiGuide)	GCTCATGAAGGACAATGCCCCGG	ASTL	ENSG00000188886	5.1235345130727	[]	[]	4	hSpCas9	negative selection	3590281
96132589	96132612	2	-	26780180	A375	viability (Avana lentiGuide)	GCTTCTGGCACGAGCACACGCGG	ASTL	ENSG00000188886	-2.99744317472294	[]	[]	-5	hSpCas9	negative selection	3590282
96132644	96132667	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	0.22974547977834883	[5]	[7,6]	6	hSpCas9	positive selection	3698936
96133997	96134020	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.09731810697139237	[4]	[5,4]	2	hSpCas9	positive selection	3698937
96135350	96135373	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	-0.1674597273541705	[4]	[4,2]	-3	hSpCas9	positive selection	3698938
96135335	96135358	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	0.15790059821456098	[4]	[5,4]	4	hSpCas9	positive selection	3698939
96132627	96132650	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCATGAAGGACAATGCCCCGG	ASTL	ENSG00000188886	0.18053681102451202	[4]	[5,5]	5	hSpCas9	positive selection	3698940
96132589	96132612	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTGGCACGAGCACACGCGG	ASTL	ENSG00000188886	0.3497940731090888	[3]	[4,5]	9	hSpCas9	positive selection	3698941
96132644	96132667	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGTGTCTCCAGAAGGGCCGGGG	ASTL	ENSG00000188886	0.07994888874439357	[6]	[4,5]	1	hSpCas9	positive selection	3807543
96133997	96134020	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.3552544266359667	[5]	[3,3]	-5	hSpCas9	positive selection	3807544
96135350	96135373	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGGGGGACATCATCCGGCCGG	ASTL	ENSG00000188886	-0.39752988092363073	[5]	[3,2]	-5	hSpCas9	positive selection	3807545
96135335	96135358	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGTGTGTGCACTCACCGGCCGG	ASTL	ENSG00000188886	0.1209138582194467	[5]	[4,4]	2	hSpCas9	positive selection	3807546
96132627	96132650	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCATGAAGGACAATGCCCCGG	ASTL	ENSG00000188886	-0.7578612652433185	[5]	[3,0]	-7	hSpCas9	positive selection	3807547
96132589	96132612	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTGGCACGAGCACACGCGG	ASTL	ENSG00000188886	0.384056123956506	[4]	[6,4]	9	hSpCas9	positive selection	3807548
96135368	96135391	2	-	26780180	A375	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.803885910293099	[]	[]	3	hSpCas9	negative selection	3915782
96133498	96133521	2	+	26780180	A375	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	1.71149903427044	[]	[]	9	hSpCas9	negative selection	3915783
96133995	96134018	2	-	26780180	A375	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.781300284731564	[]	[]	3	hSpCas9	negative selection	3915784
96137568	96137591	2	+	26780180	A375	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.754690625755336	[]	[]	3	hSpCas9	negative selection	3915785
96133954	96133977	2	+	26780180	A375	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.696759952860238	[]	[]	2	hSpCas9	negative selection	3915786
96133478	96133501	2	-	26780180	A375	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.676244109729366	[]	[]	2	hSpCas9	negative selection	3915787
96135368	96135391	2	-	26780180	HT29	viability (GeCKOv2 library)	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.813743861159244	[]	[]	3	hSpCas9	negative selection	4023748
96133498	96133521	2	+	26780180	HT29	viability (GeCKOv2 library)	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	1.92637608177604	[]	[]	9	hSpCas9	negative selection	4023749
96133995	96134018	2	-	26780180	HT29	viability (GeCKOv2 library)	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	1.31437780085494	[]	[]	6	hSpCas9	negative selection	4023750
96137568	96137591	2	+	26780180	HT29	viability (GeCKOv2 library)	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.668196846206909	[]	[]	2	hSpCas9	negative selection	4023751
96133954	96133977	2	+	26780180	HT29	viability (GeCKOv2 library)	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	1.43378877079537	[]	[]	7	hSpCas9	negative selection	4023752
96133478	96133501	2	-	26780180	HT29	viability (GeCKOv2 library)	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.305894672177219	[]	[]	0	hSpCas9	negative selection	4023753
96135368	96135391	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.4422199316013299	[3]	[1,0]	-8	hSpCas9	positive selection	4158910
96137568	96137591	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.07804185355535048	[4]	[2,3]	2	hSpCas9	positive selection	4158921
96135356	96135379	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	0.07697045707924188	[2]	[1,1]	2	hSpCas9	positive selection	4158932
96135401	96135424	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	-0.13781944087420528	[0]	[0,0]	-3	hSpCas9	positive selection	4158943
96135368	96135391	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.34124492327333966	[1]	[0,0,0,0]	-5	hSpCas9	positive selection	4222932
96137568	96137591	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.18491098066704104	[4]	[3,3,3,0]	1	hSpCas9	positive selection	4222943
96135356	96135379	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATGATGTCCCCCTCGATGAGG	ASTL	ENSG00000188886	0.5850119323893272	[3]	[0,0,0,3]	4	hSpCas9	positive selection	4222954
96135401	96135424	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTTTCCCAGGGCTCATCCTGG	ASTL	ENSG00000188886	1.171992066908884	[0]	[0,0,0,0]	8	hSpCas9	positive selection	4222965
96133478	96133501	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.14678469992506754	[3]	[3,1]	-3	hSpCas9	positive selection	4257078
96137568	96137591	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.2492326889221764	[3]	[4,2]	5	hSpCas9	positive selection	4257079
96133954	96133977	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.09290030335471389	[5]	[5,3]	2	hSpCas9	positive selection	4257080
96133498	96133521	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.23673373004553594	[2]	[1,0]	-5	hSpCas9	positive selection	4321362
96135368	96135391	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.33975369271636835	[3]	[3,3]	7	hSpCas9	positive selection	4321363
96133995	96134018	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.33252905729486026	[2]	[1,0]	-6	hSpCas9	positive selection	4321364
96132556	96132578	2	-	27760321	OCIAML3	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.10493590988243223	[670,516]	[433,421]	-1	hSpCas9	negative selection	4380090
96132580	96132602	2	-	27760321	OCIAML3	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.07743579290321842	[526,407]	[228,493]	-1	hSpCas9	negative selection	4380091
96132647	96132669	2	+	27760321	OCIAML3	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	-0.056138569779116576	[732,653]	[434,632]	0	hSpCas9	negative selection	4380092
96133478	96133500	2	-	27760321	OCIAML3	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.13184950939119447	[470,412]	[301,476]	1	hSpCas9	negative selection	4380093
96133998	96134020	2	+	27760321	OCIAML3	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.18211816268986286	[567,506]	[375,606]	2	hSpCas9	negative selection	4380094
96132556	96132578	2	-	27760321	OCIAML2	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.6175605544183433	[670,516]	[243,398]	-6	hSpCas9	negative selection	4463553
96132580	96132602	2	-	27760321	OCIAML2	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.09742239807275033	[526,407]	[293,425]	-1	hSpCas9	negative selection	4463554
96132647	96132669	2	+	27760321	OCIAML2	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.36238845559718535	[732,653]	[626,842]	5	hSpCas9	negative selection	4463555
96133478	96133500	2	-	27760321	OCIAML2	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.5397936737145651	[470,412]	[434,628]	7	hSpCas9	negative selection	4463556
96133998	96134020	2	+	27760321	OCIAML2	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.11805015763847793	[567,506]	[497,435]	1	hSpCas9	negative selection	4463557
96132556	96132578	2	-	27760321	MV411	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	0.6702756198382628	[670,516]	[860,255]	5	hSpCas9	negative selection	4547016
96132580	96132602	2	-	27760321	MV411	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.6431105225159013	[526,407]	[110,323]	-4	hSpCas9	negative selection	4547017
96132647	96132669	2	+	27760321	MV411	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.8338222390978577	[732,653]	[772,876]	6	hSpCas9	negative selection	4547018
96133478	96133500	2	-	27760321	MV411	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.048828475331786275	[470,412]	[400,150]	0	hSpCas9	negative selection	4547019
96133998	96134020	2	+	27760321	MV411	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.538905529668591	[567,506]	[538,477]	4	hSpCas9	negative selection	4547020
96132556	96132578	2	-	27760321	HL60	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	0.1457601909148828	[670,516]	[461,607]	1	hSpCas9	negative selection	4630479
96132580	96132602	2	-	27760321	HL60	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	0.0926445292117481	[526,407]	[463,340]	1	hSpCas9	negative selection	4630480
96132647	96132669	2	+	27760321	HL60	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.35494357313200753	[732,653]	[723,722]	4	hSpCas9	negative selection	4630481
96133478	96133500	2	-	27760321	HL60	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	1.353277469769535	[470,412]	[954,883]	9	hSpCas9	negative selection	4630482
96133998	96134020	2	+	27760321	HL60	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.22640339538680623	[567,506]	[433,311]	-3	hSpCas9	negative selection	4630483
96132556	96132578	2	-	27760321	HT1080	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	0.48237597571092267	[516,403]	[188,329]	2	hSpCas9	negative selection	4713942
96132580	96132602	2	-	27760321	HT1080	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	1.179458851941412	[407,318]	[380,269]	6	hSpCas9	negative selection	4713943
96132647	96132669	2	+	27760321	HT1080	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.3887520843392386	[653,510]	[331,272]	2	hSpCas9	negative selection	4713944
96133478	96133500	2	-	27760321	HT1080	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.39372992587043315	[412,321]	[135,253]	2	hSpCas9	negative selection	4713945
96133998	96134020	2	+	27760321	HT1080	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	1.7549423626634113	[506,395]	[861,327]	8	hSpCas9	negative selection	4713946
96132556	96132578	2	-	27760321	HT29	viability after 7 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.6500827048794481	[516,403]	[499,337,312]	-7	hSpCas9	negative selection	4797405
96132580	96132602	2	-	27760321	HT29	viability after 7 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	0.33216189474019814	[407,318]	[597,681,488]	5	hSpCas9	negative selection	4797406
96132647	96132669	2	+	27760321	HT29	viability after 7 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.36178796084352294	[653,510]	[974,703,1200]	5	hSpCas9	negative selection	4797407
96133478	96133500	2	-	27760321	HT29	viability after 7 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.3284453483808998	[412,321]	[589,295,275]	-5	hSpCas9	negative selection	4797408
96133998	96134020	2	+	27760321	HT29	viability after 7 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.33200046715218967	[506,395]	[525,463,403]	-5	hSpCas9	negative selection	4797409
96132556	96132578	2	-	27760321	HT29	viability after 25 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.8389257236213591	[516,403]	[343,198,340]	-6	hSpCas9	negative selection	4880868
96132580	96132602	2	-	27760321	HT29	viability after 25 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	0.07823310118018423	[407,318]	[397,452,469]	0	hSpCas9	negative selection	4880869
96132647	96132669	2	+	27760321	HT29	viability after 25 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.19101544238746648	[653,510]	[604,738,965]	2	hSpCas9	negative selection	4880870
96133478	96133500	2	-	27760321	HT29	viability after 25 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.048156824709756435	[412,321]	[306,451,471]	0	hSpCas9	negative selection	4880871
96133998	96134020	2	+	27760321	HT29	viability after 25 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.05632934140644125	[506,395]	[465,552,600]	0	hSpCas9	negative selection	4880872
96132556	96132578	2	-	27760321	HT29	viability after 22 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.7828206302159673	[516,403]	[324,283,318]	-6	hSpCas9	negative selection	4964331
96132580	96132602	2	-	27760321	HT29	viability after 22 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.11718661363262811	[407,318]	[322,471,368]	-1	hSpCas9	negative selection	4964332
96132647	96132669	2	+	27760321	HT29	viability after 22 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.21810949895617704	[653,510]	[889,585,871]	2	hSpCas9	negative selection	4964333
96133478	96133500	2	-	27760321	HT29	viability after 22 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.12218355811902777	[412,321]	[670,398,309]	1	hSpCas9	negative selection	4964334
96133998	96134020	2	+	27760321	HT29	viability after 22 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.09676697504325438	[506,395]	[557,462,440]	-1	hSpCas9	negative selection	4964335
96132556	96132578	2	-	27760321	HT29	viability after 19 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.7620958489992666	[516,403]	[453,114,374]	-6	hSpCas9	negative selection	5047794
96132580	96132602	2	-	27760321	HT29	viability after 19 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.13144321118974162	[407,318]	[412,350,377]	-1	hSpCas9	negative selection	5047795
96132647	96132669	2	+	27760321	HT29	viability after 19 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.38642152601084	[653,510]	[664,1309,624]	4	hSpCas9	negative selection	5047796
96133478	96133500	2	-	27760321	HT29	viability after 19 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.38852185997387	[412,321]	[558,540,550]	4	hSpCas9	negative selection	5047797
96133998	96134020	2	+	27760321	HT29	viability after 19 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.017063914730842178	[506,395]	[694,546,349]	0	hSpCas9	negative selection	5047798
96132556	96132578	2	-	27760321	HT29	viability after 16 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.46872119221697806	[516,403]	[299,489,316]	-5	hSpCas9	negative selection	5131257
96132580	96132602	2	-	27760321	HT29	viability after 16 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	0.17851117077674578	[407,318]	[496,356,532]	2	hSpCas9	negative selection	5131258
96132647	96132669	2	+	27760321	HT29	viability after 16 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.26429189146951537	[653,510]	[594,915,815]	3	hSpCas9	negative selection	5131259
96133478	96133500	2	-	27760321	HT29	viability after 16 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.729816896416841	[412,321]	[377,284,91]	-6	hSpCas9	negative selection	5131260
96133998	96134020	2	+	27760321	HT29	viability after 16 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.16594369940848225	[506,395]	[558,412,389]	-2	hSpCas9	negative selection	5131261
96132556	96132578	2	-	27760321	HT29	viability after 13 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.5999551233022365	[516,403]	[413,285,356]	-6	hSpCas9	negative selection	5214720
96132580	96132602	2	-	27760321	HT29	viability after 13 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.25255087581852836	[407,318]	[273,345,436]	-3	hSpCas9	negative selection	5214721
96132647	96132669	2	+	27760321	HT29	viability after 13 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.12927483783497373	[653,510]	[1015,568,637]	1	hSpCas9	negative selection	5214722
96133478	96133500	2	-	27760321	HT29	viability after 13 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.2661751923963557	[412,321]	[394,427,246]	-3	hSpCas9	negative selection	5214723
96133998	96134020	2	+	27760321	HT29	viability after 13 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	-0.2011358962702167	[506,395]	[457,540,372]	-2	hSpCas9	negative selection	5214724
96132556	96132578	2	-	27760321	HT29	viability after 10 days	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.9857613929901525	[516,403]	[224,158,478]	-8	hSpCas9	negative selection	5298183
96132580	96132602	2	-	27760321	HT29	viability after 10 days	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	0.3746537139661892	[407,318]	[217,505,1028]	5	hSpCas9	negative selection	5298184
96132647	96132669	2	+	27760321	HT29	viability after 10 days	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.27494880257070853	[653,510]	[571,1278,801]	3	hSpCas9	negative selection	5298185
96133478	96133500	2	-	27760321	HT29	viability after 10 days	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.0872198303229989	[412,321]	[593,406,296]	-1	hSpCas9	negative selection	5298186
96133998	96134020	2	+	27760321	HT29	viability after 10 days	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.27745694047948094	[506,395]	[824,443,771]	4	hSpCas9	negative selection	5298187
96132556	96132578	2	-	27760321	MOLM13	viability	CCGCTATATCCGTGTCAACTGG	ASTL	ENSG00000188886	-0.4018814413905355	[670,516]	[368,151]	-3	hSpCas9	negative selection	5381646
96132580	96132602	2	-	27760321	MOLM13	viability	CGAGCACACGCGGGCCGACCGG	ASTL	ENSG00000188886	-0.02711336423698984	[526,407]	[404,130]	0	hSpCas9	negative selection	5381647
96132647	96132669	2	+	27760321	MOLM13	viability	CGGCCCTTCTGGAGACACGTGG	ASTL	ENSG00000188886	0.6507416697793881	[732,653]	[452,749]	4	hSpCas9	negative selection	5381648
96133478	96133500	2	-	27760321	MOLM13	viability	TGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.4861906192542886	[470,412]	[434,274]	3	hSpCas9	negative selection	5381649
96133998	96134020	2	+	27760321	MOLM13	viability	CGACACCACTACCACCCATGGG	ASTL	ENSG00000188886	0.09766255321037404	[567,506]	[161,461]	0	hSpCas9	negative selection	5381650
96138363	96138386	2	+	27661255	K562	viability	GGACAGGCAGCCAGCTTACCTGG	ASTL	ENSG00000188886	0.4702180842329453	[388,402]	[519,367]	9	dCas9-KRAB	negative selection	5463875
96138390	96138413	2	+	27661255	K562	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.14497690756649056	[826,1252]	[961,868]	5	dCas9-KRAB	negative selection	5463876
96138416	96138439	2	+	27661255	K562	viability	GAGACCCCCTACACCCTCCATGG	ASTL	ENSG00000188886	-1.1182194384506263	[1584,1708]	[716,509]	-8	dCas9-KRAB	negative selection	5463877
96137987	96138010	2	-	27661255	K562	viability	GTCACGGGCGTCAGAACCCGAGG	ASTL	ENSG00000188886	0.26228950270438856	[1085,1200]	[1200,1001]	8	dCas9-KRAB	negative selection	5463878
96138079	96138102	2	-	27661255	K562	viability	GGTCAGGCAGGGAGTCATCCAGG	ASTL	ENSG00000188886	-0.04092783234800571	[729,899]	[725,548]	-2	dCas9-KRAB	negative selection	5463879
96138423	96138446	2	-	27661255	K562	viability	GGCTCTACCATGGAGGGTGTAGG	ASTL	ENSG00000188886	0.13217594820141532	[318,339]	[326,254]	4	dCas9-KRAB	negative selection	5463880
96133478	96133501	2	-	27260156	BXPC3	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.23265773686058155	[740]	[837,918,872,1025]	5	hSpCas9	negative selection	5529538
96137568	96137591	2	+	27260156	BXPC3	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.17797740956436842	[594]	[696,679,746,686]	4	hSpCas9	negative selection	5529539
96133954	96133977	2	+	27260156	BXPC3	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.1577159434804094	[2590]	[2915,2802,2953,3472]	3	hSpCas9	negative selection	5529540
96133498	96133521	2	+	27260156	BXPC3	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.13916438620755256	[293]	[351,208,274,273]	-3	hSpCas9	negative selection	5593822
96135368	96135391	2	-	27260156	BXPC3	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.2177706454514743	[823]	[742,630,895,690]	-5	hSpCas9	negative selection	5593823
96133995	96134018	2	-	27260156	BXPC3	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.06792235346330233	[256]	[236,220,230,349]	-1	hSpCas9	negative selection	5593824
96133478	96133501	2	-	27260156	A673	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.09993339701299098	[740]	[997,851,979,991]	2	hSpCas9	negative selection	5650789
96137568	96137591	2	+	27260156	A673	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.1692869337566963	[594]	[879,764,817,755]	4	hSpCas9	negative selection	5650790
96133954	96133977	2	+	27260156	A673	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.10173435558624577	[2590]	[3571,3050,3267,3499]	2	hSpCas9	negative selection	5650791
96133498	96133521	2	+	27260156	A673	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.3350176319522734	[293]	[319,310,216,274]	-7	hSpCas9	negative selection	5715073
96135368	96135391	2	-	27260156	A673	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.16934378787805804	[823]	[987,828,947,758]	-4	hSpCas9	negative selection	5715074
96133995	96134018	2	-	27260156	A673	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.04873382982621588	[256]	[326,244,362,344]	1	hSpCas9	negative selection	5715075
96133478	96133501	2	-	27260156	A375	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.28133626113294663	[740]	[1196,1184,1030,835]	4	hSpCas9	negative selection	5772040
96137568	96137591	2	+	27260156	A375	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.4234785168528386	[594]	[1072,927,828,898]	6	hSpCas9	negative selection	5772041
96133954	96133977	2	+	27260156	A375	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.3209985925426899	[2590]	[3843,4315,3511,3538]	5	hSpCas9	negative selection	5772042
96133498	96133521	2	+	27260156	A375	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.10904627570064596	[293]	[345,446,239,263]	-1	hSpCas9	negative selection	5836324
96135368	96135391	2	-	27260156	A375	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.2197251544881318	[823]	[989,1223,1156,1120]	3	hSpCas9	negative selection	5836325
96133995	96134018	2	-	27260156	A375	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.21017146052031677	[256]	[218,294,262,263]	-3	hSpCas9	negative selection	5836326
96133478	96133501	2	-	27260156	COLO741	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.36152333382796653	[740]	[1038,974,1588]	7	hSpCas9	negative selection	5893291
96137568	96137591	2	+	27260156	COLO741	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.08255915594289948	[594]	[796,760,850]	1	hSpCas9	negative selection	5893292
96133954	96133977	2	+	27260156	COLO741	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.3284972734283742	[2590]	[4182,3566,4673]	6	hSpCas9	negative selection	5893293
96133498	96133521	2	+	27260156	COLO741	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.5695097753081962	[293]	[285,214,259]	-8	hSpCas9	negative selection	5957575
96135368	96135391	2	-	27260156	COLO741	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.12894526927005878	[823]	[1052,1006,842]	-3	hSpCas9	negative selection	5957576
96133995	96134018	2	-	27260156	COLO741	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.15346811530983007	[256]	[437,368,298]	3	hSpCas9	negative selection	5957577
96133478	96133501	2	-	27260156	CAL120	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.2951295789416304	[740]	[1158,1057,1179]	4	hSpCas9	negative selection	6014542
96137568	96137591	2	+	27260156	CAL120	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.944503190219953	[594]	[1646,1311,1349]	9	hSpCas9	negative selection	6014543
96133954	96133977	2	+	27260156	CAL120	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.36896047627468764	[2590]	[5255,4070,3341]	5	hSpCas9	negative selection	6014544
96133498	96133521	2	+	27260156	CAL120	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.3106115530657343	[293]	[483,230,199]	-4	hSpCas9	negative selection	6078826
96135368	96135391	2	-	27260156	CAL120	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.3496440347731287	[823]	[963,852,623]	-5	hSpCas9	negative selection	6078827
96133995	96134018	2	-	27260156	CAL120	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.1436604053464121	[256]	[758,132,230]	2	hSpCas9	negative selection	6078828
96133478	96133501	2	-	27260156	CADOES1	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.18360014235617494	[740]	[724,833,841,727]	3	hSpCas9	negative selection	6135793
96137568	96137591	2	+	27260156	CADOES1	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.25074230105263745	[594]	[647,613,550,826]	4	hSpCas9	negative selection	6135794
96133954	96133977	2	+	27260156	CADOES1	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.30788736455249	[2590]	[2700,2931,2978,3333]	5	hSpCas9	negative selection	6135795
96133498	96133521	2	+	27260156	CADOES1	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.3492332669287549	[293]	[286,211,129,229]	-6	hSpCas9	negative selection	6200077
96135368	96135391	2	-	27260156	CADOES1	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.09270067652485448	[823]	[684,708,954,923]	1	hSpCas9	negative selection	6200078
96133995	96134018	2	-	27260156	CADOES1	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.09577540699574627	[256]	[157,298,259,306]	1	hSpCas9	negative selection	6200079
96133478	96133501	2	-	27260156	EWS502	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.05866589937758937	[740]	[731,814,886,845]	1	hSpCas9	negative selection	6257044
96137568	96137591	2	+	27260156	EWS502	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.06892900556249615	[594]	[612,857,605,553]	1	hSpCas9	negative selection	6257045
96133954	96133977	2	+	27260156	EWS502	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.19577887423380025	[2590]	[2972,3210,3107,3296]	3	hSpCas9	negative selection	6257046
96133498	96133521	2	+	27260156	EWS502	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.5397004681021184	[293]	[151,132,193,400]	-7	hSpCas9	negative selection	6321328
96135368	96135391	2	-	27260156	EWS502	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.1983814296381996	[823]	[757,841,632,804]	-4	hSpCas9	negative selection	6321329
96133995	96134018	2	-	27260156	EWS502	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.14570071568112242	[256]	[241,326,227,419]	2	hSpCas9	negative selection	6321330
96133478	96133501	2	-	27260156	EW8	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.3964414663423087	[740]	[1183,862,600,587]	7	hSpCas9	negative selection	6378295
96137568	96137591	2	+	27260156	EW8	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.15857905510447773	[594]	[452,372,405,500]	-3	hSpCas9	negative selection	6378296
96133954	96133977	2	+	27260156	EW8	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.1446317132097561	[2590]	[2581,2405,1889,2501]	2	hSpCas9	negative selection	6378297
96133498	96133521	2	+	27260156	EW8	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.14327948564350823	[293]	[338,212,210,113]	-3	hSpCas9	negative selection	6442579
96135368	96135391	2	-	27260156	EW8	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.1209058350768688	[823]	[618,785,466,608]	-2	hSpCas9	negative selection	6442580
96133995	96134018	2	-	27260156	EW8	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.31122940345784034	[256]	[351,270,225,199]	6	hSpCas9	negative selection	6442581
96133478	96133501	2	-	27260156	CORL105	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.38251175269513593	[740]	[998,1170,1378,1007]	7	hSpCas9	negative selection	6499546
96137568	96137591	2	+	27260156	CORL105	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.1523088020910176	[594]	[582,1022,767,709]	3	hSpCas9	negative selection	6499547
96133954	96133977	2	+	27260156	CORL105	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.24259402496697424	[2590]	[3493,3535,3884,3482]	4	hSpCas9	negative selection	6499548
96133498	96133521	2	+	27260156	CORL105	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.4592166423209426	[293]	[284,277,273,168]	-7	hSpCas9	negative selection	6563830
96135368	96135391	2	-	27260156	CORL105	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.3597642891593551	[823]	[632,678,768,924]	-6	hSpCas9	negative selection	6563831
96133995	96134018	2	-	27260156	CORL105	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.004688359986195323	[256]	[224,346,247,374]	0	hSpCas9	negative selection	6563832
96133478	96133501	2	-	27260156	HS294T	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.4326396381491514	[740]	[475,323,326,416]	6	hSpCas9	negative selection	6620797
96137568	96137591	2	+	27260156	HS294T	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.5376859151763931	[594]	[195,261,401,521]	7	hSpCas9	negative selection	6620798
96133954	96133977	2	+	27260156	HS294T	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.4276181712496765	[2590]	[1204,1025,1567,1663]	6	hSpCas9	negative selection	6620799
96133498	96133521	2	+	27260156	HS294T	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.35790782785846587	[293]	[117,74,55,105]	-5	hSpCas9	negative selection	6685081
96135368	96135391	2	-	27260156	HS294T	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.24837106610006188	[823]	[245,284,231,318]	-3	hSpCas9	negative selection	6685082
96133995	96134018	2	-	27260156	HS294T	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.14426788474685592	[256]	[51,232,81,65]	2	hSpCas9	negative selection	6685083
96133478	96133501	2	-	27260156	HCC44	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.3063790761703692	[740]	[1259,850,1127,962]	5	hSpCas9	negative selection	6742048
96137568	96137591	2	+	27260156	HCC44	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.4687900188455501	[594]	[1011,938,1047,750]	7	hSpCas9	negative selection	6742049
96133954	96133977	2	+	27260156	HCC44	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.1392447466018738	[2590]	[3388,2473,3860,3384]	2	hSpCas9	negative selection	6742050
96133498	96133521	2	+	27260156	HCC44	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.24384991378432308	[293]	[192,333,226,339]	-4	hSpCas9	negative selection	6806332
96135368	96135391	2	-	27260156	HCC44	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.6211995669232344	[823]	[809,381,966,379]	-7	hSpCas9	negative selection	6806333
96133995	96134018	2	-	27260156	HCC44	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.048942012184649886	[256]	[159,310,346,298]	-1	hSpCas9	negative selection	6806334
96133478	96133501	2	-	27260156	G402	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.3882299201973477	[740]	[1266,1772,928,823]	5	hSpCas9	negative selection	6863299
96137568	96137591	2	+	27260156	G402	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.15578584131034226	[594]	[419,614,845,685]	-2	hSpCas9	negative selection	6863300
96133954	96133977	2	+	27260156	G402	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.1288620804222913	[2590]	[3533,3030,3637,3590]	1	hSpCas9	negative selection	6863301
96133498	96133521	2	+	27260156	G402	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.14123071573679935	[293]	[538,244,405,144]	-2	hSpCas9	negative selection	6927583
96135368	96135391	2	-	27260156	G402	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.442715081178601	[823]	[786,743,475,945]	-5	hSpCas9	negative selection	6927584
96133995	96134018	2	-	27260156	G402	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.85648836949933	[256]	[315,154,137,105]	-7	hSpCas9	negative selection	6927585
96133478	96133501	2	-	27260156	L33	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.2979671784042469	[740]	[835,364,592,974]	6	hSpCas9	negative selection	6984550
96137568	96137591	2	+	27260156	L33	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.43157032708956095	[594]	[824,350,488,749]	8	hSpCas9	negative selection	6984551
96133954	96133977	2	+	27260156	L33	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.2443542238109222	[2590]	[2853,1219,2071,3153]	5	hSpCas9	negative selection	6984552
96133498	96133521	2	+	27260156	L33	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.17882593789867895	[293]	[316,104,131,253]	-4	hSpCas9	negative selection	7048834
96135368	96135391	2	-	27260156	L33	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.010842765556996148	[823]	[742,475,368,829]	0	hSpCas9	negative selection	7048835
96133995	96134018	2	-	27260156	L33	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.02998311979380286	[256]	[377,76,181,191]	0	hSpCas9	negative selection	7048836
96133478	96133501	2	-	27260156	K562	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.492808043642868	[740]	[800,1434,665,823]	6	hSpCas9	negative selection	7105801
96137568	96137591	2	+	27260156	K562	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.26557268017619634	[594]	[654,934,482,496]	3	hSpCas9	negative selection	7105802
96133954	96133977	2	+	27260156	K562	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.3039773767120555	[2590]	[3590,3296,1927,2635]	4	hSpCas9	negative selection	7105803
96133498	96133521	2	+	27260156	K562	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.7976565693649581	[293]	[187,135,211,74]	-7	hSpCas9	negative selection	7170085
96135368	96135391	2	-	27260156	K562	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.600948840124846	[823]	[415,559,748,229]	-6	hSpCas9	negative selection	7170086
96133995	96134018	2	-	27260156	K562	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.9604963236935216	[256]	[279,220,800,445]	9	hSpCas9	negative selection	7170087
96133478	96133501	2	-	27260156	HT29	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.0456687287172447	[740]	[871,972,878,980]	0	hSpCas9	negative selection	7227052
96137568	96137591	2	+	27260156	HT29	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.20446960372496698	[594]	[902,953,775,723]	4	hSpCas9	negative selection	7227053
96133954	96133977	2	+	27260156	HT29	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.23621130462960194	[2590]	[3936,4077,3515,3372]	4	hSpCas9	negative selection	7227054
96133498	96133521	2	+	27260156	HT29	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.5253388173828922	[293]	[381,237,169,214]	-7	hSpCas9	negative selection	7291336
96135368	96135391	2	-	27260156	HT29	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.015036651673663859	[823]	[1213,983,1050,754]	0	hSpCas9	negative selection	7291337
96133995	96134018	2	-	27260156	HT29	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.27267389055145685	[256]	[287,262,205,275]	-5	hSpCas9	negative selection	7291338
96133478	96133501	2	-	27260156	MHHES1	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.2769865459740941	[740]	[1069,1175,1061,789]	5	hSpCas9	negative selection	7348303
96137568	96137591	2	+	27260156	MHHES1	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.010554954997947119	[594]	[767,553,840,550]	0	hSpCas9	negative selection	7348304
96133954	96133977	2	+	27260156	MHHES1	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.29384909668102255	[2590]	[3770,4142,3530,2998]	5	hSpCas9	negative selection	7348305
96133498	96133521	2	+	27260156	MHHES1	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.44459180188166736	[293]	[265,305,215,198]	-7	hSpCas9	negative selection	7412587
96135368	96135391	2	-	27260156	MHHES1	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.3312518848075653	[823]	[650,895,838,588]	-6	hSpCas9	negative selection	7412588
96133995	96134018	2	-	27260156	MHHES1	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.014683678429915803	[256]	[151,246,509,225]	0	hSpCas9	negative selection	7412589
96133478	96133501	2	-	27260156	MEWO	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.1430023994837386	[740]	[886,731,700]	3	hSpCas9	negative selection	7469554
96137568	96137591	2	+	27260156	MEWO	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.21717433371879408	[594]	[801,675,492]	5	hSpCas9	negative selection	7469555
96133954	96133977	2	+	27260156	MEWO	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.2060192804213421	[2590]	[3173,2587,2699]	4	hSpCas9	negative selection	7469556
96133498	96133521	2	+	27260156	MEWO	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.18545160766530666	[293]	[187,269,256]	-4	hSpCas9	negative selection	7533838
96135368	96135391	2	-	27260156	MEWO	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.11388161123504226	[823]	[684,651,794]	-2	hSpCas9	negative selection	7533839
96133995	96134018	2	-	27260156	MEWO	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.13124045514134197	[256]	[271,187,331]	3	hSpCas9	negative selection	7533840
96133478	96133501	2	-	27260156	LNCAPCLONEFGC	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.16185025931629815	[740]	[644,771,953,662]	2	hSpCas9	negative selection	7590805
96137568	96137591	2	+	27260156	LNCAPCLONEFGC	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.3949940616804773	[594]	[577,728,818,725]	6	hSpCas9	negative selection	7590806
96133954	96133977	2	+	27260156	LNCAPCLONEFGC	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.30705059990422745	[2590]	[2780,2539,3311,3066]	5	hSpCas9	negative selection	7590807
96133498	96133521	2	+	27260156	LNCAPCLONEFGC	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.4002745723978053	[293]	[137,228,211,228]	-6	hSpCas9	negative selection	7655089
96135368	96135391	2	-	27260156	LNCAPCLONEFGC	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.015404221937570073	[823]	[528,821,899,724]	0	hSpCas9	negative selection	7655090
96133995	96134018	2	-	27260156	LNCAPCLONEFGC	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.0833618334297741	[256]	[156,256,269,200]	-1	hSpCas9	negative selection	7655091
96133478	96133501	2	-	27260156	PANC0327	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.16577693277497585	[740]	[906,715,679,666]	2	hSpCas9	negative selection	7712056
96137568	96137591	2	+	27260156	PANC0327	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.5631576948433572	[594]	[1104,698,467,887]	8	hSpCas9	negative selection	7712057
96133954	96133977	2	+	27260156	PANC0327	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.21163502282086455	[2590]	[3075,2228,2599,2844]	3	hSpCas9	negative selection	7712058
96133498	96133521	2	+	27260156	PANC0327	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	0.23785968368271004	[293]	[453,382,207,188]	3	hSpCas9	negative selection	7776340
96135368	96135391	2	-	27260156	PANC0327	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.34048471724405016	[823]	[1969,548,675,645]	5	hSpCas9	negative selection	7776341
96133995	96134018	2	-	27260156	PANC0327	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.3221259948059386	[256]	[364,291,168,320]	5	hSpCas9	negative selection	7776342
96133478	96133501	2	-	27260156	NCIH2009	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.5609553928329151	[740]	[1808,1252,1577]	7	hSpCas9	negative selection	7833307
96137568	96137591	2	+	27260156	NCIH2009	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.16204627217322914	[594]	[1370,761,745]	2	hSpCas9	negative selection	7833308
96133954	96133977	2	+	27260156	NCIH2009	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.3882888534536444	[2590]	[5208,4251,4846]	5	hSpCas9	negative selection	7833309
96133498	96133521	2	+	27260156	NCIH2009	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.38355092260928914	[293]	[350,381,216]	-5	hSpCas9	negative selection	7897591
96135368	96135391	2	-	27260156	NCIH2009	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.059022744706172414	[823]	[1358,1117,1151]	0	hSpCas9	negative selection	7897592
96133995	96134018	2	-	27260156	NCIH2009	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.0981963125641876	[256]	[296,282,556]	1	hSpCas9	negative selection	7897593
96133478	96133501	2	-	27260156	NCIH1373	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.6162158861740833	[740]	[1702,1031,1090,357]	6	hSpCas9	negative selection	7954558
96137568	96137591	2	+	27260156	NCIH1373	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.1727832101301356	[594]	[757,644,940,173]	1	hSpCas9	negative selection	7954559
96133954	96133977	2	+	27260156	NCIH1373	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.6400294438586207	[2590]	[4430,4908,4195,1179]	6	hSpCas9	negative selection	7954560
96133498	96133521	2	+	27260156	NCIH1373	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	0.1319277028443745	[293]	[443,573,247,40]	1	hSpCas9	negative selection	8018842
96135368	96135391	2	-	27260156	NCIH1373	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.622470956867647	[823]	[794,770,300,142]	-6	hSpCas9	negative selection	8018843
96133995	96134018	2	-	27260156	NCIH1373	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.004679844099118036	[256]	[518,80,84,141]	0	hSpCas9	negative selection	8018844
96133478	96133501	2	-	27260156	PATU8902	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.807851159527523	[740]	[1948,1838,1502,2023]	8	hSpCas9	negative selection	8075809
96137568	96137591	2	+	27260156	PATU8902	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.014957960224174505	[594]	[906,576,828,1055]	0	hSpCas9	negative selection	8075810
96133954	96133977	2	+	27260156	PATU8902	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.25488205521649565	[2590]	[3550,4192,4153,5479]	2	hSpCas9	negative selection	8075811
96133498	96133521	2	+	27260156	PATU8902	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.9571931602135234	[293]	[190,316,202,122]	-7	hSpCas9	negative selection	8140093
96135368	96135391	2	-	27260156	PATU8902	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.3789993823348646	[823]	[1175,521,847,993]	-4	hSpCas9	negative selection	8140094
96133995	96134018	2	-	27260156	PATU8902	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.2456829652759348	[256]	[211,162,437,364]	-2	hSpCas9	negative selection	8140095
96133478	96133501	2	-	27260156	PANC1	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.21225978270992674	[740]	[554,876,733,793]	3	hSpCas9	negative selection	8197060
96137568	96137591	2	+	27260156	PANC1	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.350128788757937	[594]	[374,477,411,355]	-5	hSpCas9	negative selection	8197061
96133954	96133977	2	+	27260156	PANC1	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.11860781759451822	[2590]	[2488,3242,2413,1756]	1	hSpCas9	negative selection	8197062
96133498	96133521	2	+	27260156	PANC1	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.6180078157610182	[293]	[128,288,156,114]	-7	hSpCas9	negative selection	8261344
96135368	96135391	2	-	27260156	PANC1	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.2147915031053822	[823]	[620,670,513,630]	-3	hSpCas9	negative selection	8261345
96133995	96134018	2	-	27260156	PANC1	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.08286770357219964	[256]	[207,231,180,212]	-1	hSpCas9	negative selection	8261346
96133478	96133501	2	-	27260156	PANC0813	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.40757701600062035	[740]	[1244,1203,1071,1105]	6	hSpCas9	negative selection	8318311
96137568	96137591	2	+	27260156	PANC0813	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.3706194171199007	[594]	[969,738,959,947]	6	hSpCas9	negative selection	8318312
96133954	96133977	2	+	27260156	PANC0813	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.24084134728560436	[2590]	[3874,2743,3936,3837]	4	hSpCas9	negative selection	8318313
96133498	96133521	2	+	27260156	PANC0813	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.759720764670477	[293]	[285,166,166,202]	-8	hSpCas9	negative selection	8382595
96135368	96135391	2	-	27260156	PANC0813	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.09532790836789584	[823]	[997,945,978,718]	-1	hSpCas9	negative selection	8382596
96133995	96134018	2	-	27260156	PANC0813	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.28713822898992725	[256]	[241,229,306,211]	-4	hSpCas9	negative selection	8382597
96133478	96133501	2	-	27260156	RDES	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.23433723550733931	[740]	[820,1059,1030,1118]	4	hSpCas9	negative selection	8439562
96137568	96137591	2	+	27260156	RDES	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.2775176986029468	[594]	[628,793,871,1085]	4	hSpCas9	negative selection	8439563
96133954	96133977	2	+	27260156	RDES	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.22201390296421364	[2590]	[2929,3161,3712,4267]	3	hSpCas9	negative selection	8439564
96133498	96133521	2	+	27260156	RDES	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.17272297201683995	[293]	[276,310,282,325]	-3	hSpCas9	negative selection	8503846
96135368	96135391	2	-	27260156	RDES	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.46937883870615643	[823]	[581,542,682,991]	-7	hSpCas9	negative selection	8503847
96133995	96134018	2	-	27260156	RDES	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.19675226931550538	[256]	[219,264,273,274]	-3	hSpCas9	negative selection	8503848
96133478	96133501	2	-	27260156	PC3	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.14533280788038072	[740]	[506,672,1318,1039]	3	hSpCas9	negative selection	8560813
96137568	96137591	2	+	27260156	PC3	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.26007269342227607	[594]	[577,544,1137,727]	5	hSpCas9	negative selection	8560814
96133954	96133977	2	+	27260156	PC3	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.04637323431683926	[2590]	[1600,2514,4940,2726]	1	hSpCas9	negative selection	8560815
96133498	96133521	2	+	27260156	PC3	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.39170157697929564	[293]	[161,225,388,180]	-7	hSpCas9	negative selection	8625097
96135368	96135391	2	-	27260156	PC3	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.13649421369904002	[823]	[454,766,1064,886]	-3	hSpCas9	negative selection	8625098
96133995	96134018	2	-	27260156	PC3	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.12396735625691002	[256]	[113,218,386,318]	-3	hSpCas9	negative selection	8625099
96133478	96133501	2	-	27260156	PATU8988T	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	-0.08724118632466649	[740]	[672,740,536,759]	-1	hSpCas9	negative selection	8682064
96137568	96137591	2	+	27260156	PATU8988T	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.509604951777419	[594]	[1108,458,890,776]	8	hSpCas9	negative selection	8682065
96133954	96133977	2	+	27260156	PATU8988T	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.10506858295756771	[2590]	[2918,2863,2189,2831]	1	hSpCas9	negative selection	8682066
96133498	96133521	2	+	27260156	PATU8988T	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	0.05569453540108871	[293]	[337,251,213,380]	1	hSpCas9	negative selection	8746348
96135368	96135391	2	-	27260156	PATU8988T	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.1501522275738696	[823]	[633,772,893,558]	-3	hSpCas9	negative selection	8746349
96133995	96134018	2	-	27260156	PATU8988T	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.07714829134850854	[256]	[211,173,280,381]	1	hSpCas9	negative selection	8746350
96133478	96133501	2	-	27260156	T47D	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.0918738414814052	[740]	[935,866,915,966]	2	hSpCas9	negative selection	8803315
96137568	96137591	2	+	27260156	T47D	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.26028575663642733	[594]	[958,792,798,771]	5	hSpCas9	negative selection	8803316
96133954	96133977	2	+	27260156	T47D	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.1447747950741176	[2590]	[3411,3156,3422,3370]	3	hSpCas9	negative selection	8803317
96133498	96133521	2	+	27260156	T47D	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.19328062756145203	[293]	[338,301,252,304]	-4	hSpCas9	negative selection	8867599
96135368	96135391	2	-	27260156	T47D	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.07540520954060892	[823]	[939,859,999,844]	-2	hSpCas9	negative selection	8867600
96133995	96134018	2	-	27260156	T47D	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.1732321857500112	[256]	[349,280,314,411]	3	hSpCas9	negative selection	8867601
96133478	96133501	2	-	27260156	SU8686	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.5968137446992853	[740]	[1051,1064,1178,1162]	8	hSpCas9	negative selection	8924566
96137568	96137591	2	+	27260156	SU8686	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.3664040813177542	[594]	[739,613,766,970]	6	hSpCas9	negative selection	8924567
96133954	96133977	2	+	27260156	SU8686	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.25447489422450076	[2590]	[2766,2634,3557,3438]	4	hSpCas9	negative selection	8924568
96133498	96133521	2	+	27260156	SU8686	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.2519432092888193	[293]	[260,208,213,304]	-4	hSpCas9	negative selection	8988850
96135368	96135391	2	-	27260156	SU8686	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.37121647415232517	[823]	[585,552,701,710]	-6	hSpCas9	negative selection	8988851
96133995	96134018	2	-	27260156	SU8686	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.1758333561549682	[256]	[201,218,270,210]	-3	hSpCas9	negative selection	8988852
96133478	96133501	2	-	27260156	SKES1	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.1526660682487403	[740]	[762,855,928,734]	3	hSpCas9	negative selection	9045817
96137568	96137591	2	+	27260156	SKES1	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.26207385457066495	[594]	[516,791,821,691]	5	hSpCas9	negative selection	9045818
96133954	96133977	2	+	27260156	SKES1	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.09712284443520236	[2590]	[3335,3172,2352,2350]	2	hSpCas9	negative selection	9045819
96133498	96133521	2	+	27260156	SKES1	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.041763522627003	[293]	[348,332,324,158]	-1	hSpCas9	negative selection	9110101
96135368	96135391	2	-	27260156	SKES1	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.13589236809436211	[823]	[805,825,722,657]	-3	hSpCas9	negative selection	9110102
96133995	96134018	2	-	27260156	SKES1	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.22005296909181482	[256]	[214,260,251,160]	-5	hSpCas9	negative selection	9110103
96133478	96133501	2	-	27260156	TOV112D	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.07321104558052338	[740]	[633,850,869,771]	1	hSpCas9	negative selection	9167068
96137568	96137591	2	+	27260156	TOV112D	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	-0.029132899065643758	[594]	[428,879,651,437]	0	hSpCas9	negative selection	9167069
96133954	96133977	2	+	27260156	TOV112D	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.24319034539970907	[2590]	[3203,4306,2446,2649]	4	hSpCas9	negative selection	9167070
96133498	96133521	2	+	27260156	TOV112D	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.4616535477916154	[293]	[287,309,114,172]	-7	hSpCas9	negative selection	9231352
96135368	96135391	2	-	27260156	TOV112D	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.09192866034111813	[823]	[838,670,970,599]	-2	hSpCas9	negative selection	9231353
96133995	96134018	2	-	27260156	TOV112D	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	0.2729081696269374	[256]	[505,354,180,230]	5	hSpCas9	negative selection	9231354
96133478	96133501	2	-	27260156	TC71	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.0127457288319901	[740]	[858,811,686,852]	0	hSpCas9	negative selection	9288319
96137568	96137591	2	+	27260156	TC71	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.1358047360215351	[594]	[642,679,655,834]	3	hSpCas9	negative selection	9288320
96133954	96133977	2	+	27260156	TC71	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.08228454082867831	[2590]	[3042,2939,2703,3088]	2	hSpCas9	negative selection	9288321
96133498	96133521	2	+	27260156	TC71	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.46775638545280074	[293]	[193,215,230,273]	-8	hSpCas9	negative selection	9352603
96135368	96135391	2	-	27260156	TC71	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	-0.1995038861062961	[823]	[667,791,791,829]	-5	hSpCas9	negative selection	9352604
96133995	96134018	2	-	27260156	TC71	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.24375477519755295	[256]	[189,270,221,249]	-6	hSpCas9	negative selection	9352605
96133478	96133501	2	-	27260156	TC32	viability	TTGAACGTTCCACGTGCATCAGG	ASTL	ENSG00000188886	0.3050684640095541	[740]	[773,626,1108,1032]	5	hSpCas9	negative selection	9409570
96137568	96137591	2	+	27260156	TC32	viability	CCCTCACCTTGGTTAATTGCAGG	ASTL	ENSG00000188886	0.2290308761574073	[594]	[556,465,993,712]	4	hSpCas9	negative selection	9409571
96133954	96133977	2	+	27260156	TC32	viability	TGCTCACTCACCGTACTTGCTGG	ASTL	ENSG00000188886	0.3423869456312234	[2590]	[2835,2967,3343,3122]	6	hSpCas9	negative selection	9409572
96133498	96133521	2	+	27260156	TC32	viability	CAAACTCCGCAAGAGCCTCCAGG	ASTL	ENSG00000188886	-0.25055917754929646	[293]	[225,134,366,249]	-4	hSpCas9	negative selection	9473854
96135368	96135391	2	-	27260156	TC32	viability	AGAGAGCAGCTTCCTCATCGAGG	ASTL	ENSG00000188886	0.16390835672898152	[823]	[848,705,1067,892]	3	hSpCas9	negative selection	9473855
96133995	96134018	2	-	27260156	TC32	viability	CATGGGTGGTAGTGGTGTCGTGG	ASTL	ENSG00000188886	-0.14861088997207117	[256]	[195,196,219,257]	-3	hSpCas9	negative selection	9473856
96129875	96129898	2	-	27869803	HPAFII	viability after 27 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.5675730864955553	[91]	[66,3,NaN]	-4	hSpCas9	negative selection	9576182
96132654	96132677	2	+	27869803	HPAFII	viability after 27 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.23984723704932015	[157]	[180,28,NaN]	2	hSpCas9	negative selection	9576183
96133469	96133492	2	+	27869803	HPAFII	viability after 27 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-2.587885199175922	[104]	[0,15,NaN]	-8	hSpCas9	negative selection	9576184
96133996	96134019	2	+	27869803	HPAFII	viability after 27 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.5478262268683611	[622]	[750,251,NaN]	4	hSpCas9	negative selection	9576185
96135365	96135388	2	-	27869803	HPAFII	viability after 27 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-1.389557281796472	[163]	[63,6,NaN]	-7	hSpCas9	negative selection	9576186
96137682	96137705	2	+	27869803	HPAFII	viability after 27 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-1.0704633486589703	[133]	[32,33,NaN]	-6	hSpCas9	negative selection	9576187
96129875	96129898	2	-	27869803	HPAFII	viability after 15 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.3115466152026445	[91]	[128,48,NaN]	-3	hSpCas9	negative selection	9658631
96132654	96132677	2	+	27869803	HPAFII	viability after 15 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	0.3293818083840041	[157]	[303,156,NaN]	4	hSpCas9	negative selection	9658632
96133469	96133492	2	+	27869803	HPAFII	viability after 15 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-1.4652756574686845	[104]	[67,23,NaN]	-8	hSpCas9	negative selection	9658633
96133996	96134019	2	+	27869803	HPAFII	viability after 15 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.07266954909576828	[622]	[1153,314,NaN]	-1	hSpCas9	negative selection	9658634
96135365	96135388	2	-	27869803	HPAFII	viability after 15 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-0.7491998137354912	[163]	[213,36,NaN]	-7	hSpCas9	negative selection	9658635
96137682	96137705	2	+	27869803	HPAFII	viability after 15 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.7935200364099145	[133]	[116,61,NaN]	-7	hSpCas9	negative selection	9658636
96129875	96129898	2	-	27869803	ASPC1	viability after 36 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-5.269928513768287	[110]	[0,0,0]	-9	hSpCas9	negative selection	9741080
96132654	96132677	2	+	27869803	ASPC1	viability after 36 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.9748653148603044	[197]	[121,0,0]	-7	hSpCas9	negative selection	9741081
96133469	96133492	2	+	27869803	ASPC1	viability after 36 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	0.4700599155982226	[207]	[183,92,46]	5	hSpCas9	negative selection	9741082
96133996	96134019	2	+	27869803	ASPC1	viability after 36 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.7856655317328167	[1719]	[1095,479,1421]	7	hSpCas9	negative selection	9741083
96135365	96135388	2	-	27869803	ASPC1	viability after 36 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.3062472255612352	[497]	[22,261,309]	3	hSpCas9	negative selection	9741084
96137682	96137705	2	+	27869803	ASPC1	viability after 36 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.43131089020472	[405]	[225,127,0]	-4	hSpCas9	negative selection	9741085
96129875	96129898	2	-	27869803	PATU8988S	viability after 35 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-1.7862049149957382	[140]	[0,31,NaN]	-8	hSpCas9	negative selection	9823529
96132654	96132677	2	+	27869803	PATU8988S	viability after 35 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	1.4995461160178905	[268]	[233,378,NaN]	9	hSpCas9	negative selection	9823530
96133469	96133492	2	+	27869803	PATU8988S	viability after 35 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.18928956759684468	[149]	[45,59,NaN]	-2	hSpCas9	negative selection	9823531
96133996	96134019	2	+	27869803	PATU8988S	viability after 35 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	-0.2324522203243915	[1531]	[609,439,NaN]	-2	hSpCas9	negative selection	9823532
96135365	96135388	2	-	27869803	PATU8988S	viability after 35 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.3959329259989398	[457]	[334,149,NaN]	4	hSpCas9	negative selection	9823533
96137682	96137705	2	+	27869803	PATU8988S	viability after 35 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.3391331862505419	[220]	[153,70,NaN]	4	hSpCas9	negative selection	9823534
96129875	96129898	2	-	27869803	PATU8988S	viability after 31 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.9976899725548634	[140]	[10,49,NaN]	-7	hSpCas9	negative selection	9905978
96132654	96132677	2	+	27869803	PATU8988S	viability after 31 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	1.0943514665697112	[268]	[144,335,NaN]	9	hSpCas9	negative selection	9905979
96133469	96133492	2	+	27869803	PATU8988S	viability after 31 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-0.005144007578460563	[149]	[52,67,NaN]	0	hSpCas9	negative selection	9905980
96133996	96134019	2	+	27869803	PATU8988S	viability after 31 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.04171985478172968	[1531]	[425,886,NaN]	0	hSpCas9	negative selection	9905981
96135365	96135388	2	-	27869803	PATU8988S	viability after 31 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	0.1340608684399071	[457]	[239,149,NaN]	1	hSpCas9	negative selection	9905982
96137682	96137705	2	+	27869803	PATU8988S	viability after 31 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.49884244041411585	[220]	[142,100,NaN]	6	hSpCas9	negative selection	9905983
96129875	96129898	2	-	27869803	HPAFII	viability after 35 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.9383308862741602	[91]	[44,0,NaN]	-5	hSpCas9	negative selection	9988427
96132654	96132677	2	+	27869803	HPAFII	viability after 35 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.011070433467052165	[157]	[124,27,NaN]	0	hSpCas9	negative selection	9988428
96133469	96133492	2	+	27869803	HPAFII	viability after 35 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-5.732156964669448	[104]	[0,0,NaN]	-9	hSpCas9	negative selection	9988429
96133996	96134019	2	+	27869803	HPAFII	viability after 35 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.4715723185455192	[622]	[624,225,NaN]	3	hSpCas9	negative selection	9988430
96135365	96135388	2	-	27869803	HPAFII	viability after 35 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-2.714600836540994	[163]	[14,9,NaN]	-8	hSpCas9	negative selection	9988431
96137682	96137705	2	+	27869803	HPAFII	viability after 35 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	-0.1458971240486152	[133]	[97,19,NaN]	-1	hSpCas9	negative selection	9988432
96129875	96129898	2	-	27869803	HPAFII	viability after 31 days	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.5453868676923073	[91]	[54,13,NaN]	-4	hSpCas9	negative selection	10070876
96132654	96132677	2	+	27869803	HPAFII	viability after 31 days	TCTGGAGACACGTGGGCGCCAGG	ASTL	ENSG00000188886	-0.01484747632619976	[157]	[115,56,NaN]	0	hSpCas9	negative selection	10070877
96133469	96133492	2	+	27869803	HPAFII	viability after 31 days	GGTGACAAACCTGATGCACGTGG	ASTL	ENSG00000188886	-4.118373631717521	[104]	[0,5,NaN]	-9	hSpCas9	negative selection	10070878
96133996	96134019	2	+	27869803	HPAFII	viability after 31 days	CACGACACCACTACCACCCATGG	ASTL	ENSG00000188886	0.3211826668033553	[622]	[644,209,NaN]	2	hSpCas9	negative selection	10070879
96135365	96135388	2	-	27869803	HPAFII	viability after 31 days	GAGCAGCTTCCTCATCGAGGGGG	ASTL	ENSG00000188886	-2.1965960835074494	[163]	[32,5,NaN]	-8	hSpCas9	negative selection	10070880
96137682	96137705	2	+	27869803	HPAFII	viability after 31 days	GGCGCTCCTAGGATCACACCTGG	ASTL	ENSG00000188886	0.21578184142350887	[133]	[105,66,NaN]	1	hSpCas9	negative selection	10070881
96133510	96133533	2	+	28162770	P31FUJ	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-1.2646510704537184	[228]	[111]	-7	hSpCas9	negative selection	10114897
96137661	96137684	2	+	28162770	P31FUJ	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.024106098622573832	[235]	[281]	0	hSpCas9	negative selection	10114898
96137588	96137611	2	+	28162770	P31FUJ	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.24389991329770933	[521]	[517]	-2	hSpCas9	negative selection	10114899
96137574	96137597	2	-	28162770	P31FUJ	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.8331947457051407	[281]	[185]	-6	hSpCas9	negative selection	10114900
96134032	96134055	2	+	28162770	P31FUJ	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-4.320265045664717	[16]	[0]	-9	hSpCas9	negative selection	10114901
96133992	96134015	2	-	28162770	P31FUJ	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-1.0292688103292469	[32]	[18]	-6	hSpCas9	negative selection	10114902
96129908	96129931	2	+	28162770	P31FUJ	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.31589782017784085	[267]	[252]	-3	hSpCas9	negative selection	10114903
96129875	96129898	2	-	28162770	P31FUJ	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.34122466430036397	[220]	[204]	-3	hSpCas9	negative selection	10114904
96129837	96129860	2	-	28162770	P31FUJ	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.34606009677035965	[236]	[353]	4	hSpCas9	negative selection	10114905
96138390	96138413	2	+	28162770	P31FUJ	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.1619808672246818	[158]	[166]	-1	hSpCas9	negative selection	10114906
96133510	96133533	2	+	28162770	TF1	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10284263
96137661	96137684	2	+	28162770	TF1	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10284264
96137588	96137611	2	+	28162770	TF1	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10284265
96137574	96137597	2	-	28162770	TF1	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10284266
96134032	96134055	2	+	28162770	TF1	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10284267
96133992	96134015	2	-	28162770	TF1	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10284268
96129908	96129931	2	+	28162770	TF1	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10284269
96129875	96129898	2	-	28162770	TF1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10284270
96129837	96129860	2	-	28162770	TF1	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	NaN	[NaN]	[232]	1	hSpCas9	negative selection	10284271
96138390	96138413	2	+	28162770	TF1	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10284272
96133510	96133533	2	+	28162770	SKM1	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.5740741845784199	[47]	[56]	-4	hSpCas9	negative selection	10453629
96137661	96137684	2	+	28162770	SKM1	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.4675049191729793	[53]	[131]	4	hSpCas9	negative selection	10453630
96137588	96137611	2	+	28162770	SKM1	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.21319245534648157	[119]	[182]	-2	hSpCas9	negative selection	10453631
96137574	96137597	2	-	28162770	SKM1	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.2910609664646304	[91]	[198]	3	hSpCas9	negative selection	10453632
96134032	96134055	2	+	28162770	SKM1	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-1.8220016980220053	[3]	[1]	-8	hSpCas9	negative selection	10453633
96133992	96134015	2	-	28162770	SKM1	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10453634
96129908	96129931	2	+	28162770	SKM1	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.343336033924655	[69]	[156]	3	hSpCas9	negative selection	10453635
96129875	96129898	2	-	28162770	SKM1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.03597929710556669	[31]	[57]	0	hSpCas9	negative selection	10453636
96129837	96129860	2	-	28162770	SKM1	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.6945738277189005	[35]	[102]	6	hSpCas9	negative selection	10453637
96138390	96138413	2	+	28162770	SKM1	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.12685627955042644	[41]	[67]	-1	hSpCas9	negative selection	10453638
96133510	96133533	2	+	28162770	SKM1	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.5740741845784199	[47]	[56]	-4	hSpCas9	negative selection	10622995
96137661	96137684	2	+	28162770	SKM1	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.4675049191729793	[53]	[131]	4	hSpCas9	negative selection	10622996
96137588	96137611	2	+	28162770	SKM1	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.21319245534648157	[119]	[182]	-2	hSpCas9	negative selection	10622997
96137574	96137597	2	-	28162770	SKM1	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.2910609664646304	[91]	[198]	3	hSpCas9	negative selection	10622998
96134032	96134055	2	+	28162770	SKM1	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-1.8220016980220053	[3]	[1]	-8	hSpCas9	negative selection	10622999
96133992	96134015	2	-	28162770	SKM1	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10623000
96129908	96129931	2	+	28162770	SKM1	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.343336033924655	[69]	[156]	3	hSpCas9	negative selection	10623001
96129875	96129898	2	-	28162770	SKM1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.03597929710556669	[31]	[57]	0	hSpCas9	negative selection	10623002
96129837	96129860	2	-	28162770	SKM1	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.6945738277189005	[35]	[102]	6	hSpCas9	negative selection	10623003
96138390	96138413	2	+	28162770	SKM1	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.12685627955042644	[41]	[67]	-1	hSpCas9	negative selection	10623004
96133510	96133533	2	+	28162770	PL21	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	0.02564188325718375	[236]	[104]	0	hSpCas9	negative selection	10792361
96137661	96137684	2	+	28162770	PL21	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.6855664416595617	[109]	[76]	6	hSpCas9	negative selection	10792362
96137588	96137611	2	+	28162770	PL21	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.3287888513175081	[504]	[174]	-2	hSpCas9	negative selection	10792363
96137574	96137597	2	-	28162770	PL21	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.2376691924481818	[297]	[109]	-2	hSpCas9	negative selection	10792364
96134032	96134055	2	+	28162770	PL21	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-0.2404329768966611	[18]	[6]	-2	hSpCas9	negative selection	10792365
96133992	96134015	2	-	28162770	PL21	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	0.39278469243171577	[20]	[11]	3	hSpCas9	negative selection	10792366
96129908	96129931	2	+	28162770	PL21	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.4529056848692868	[234]	[139]	4	hSpCas9	negative selection	10792367
96129875	96129898	2	-	28162770	PL21	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.05076199045109342	[121]	[54]	0	hSpCas9	negative selection	10792368
96129837	96129860	2	-	28162770	PL21	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.8782115196019578	[164]	[131]	7	hSpCas9	negative selection	10792369
96138390	96138413	2	+	28162770	PL21	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.344529523824495	[113]	[62]	3	hSpCas9	negative selection	10792370
96133510	96133533	2	+	28162770	P31FUJ	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-1.2646510704537184	[228]	[111]	-7	hSpCas9	negative selection	10961727
96137661	96137684	2	+	28162770	P31FUJ	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.024106098622573832	[235]	[281]	0	hSpCas9	negative selection	10961728
96137588	96137611	2	+	28162770	P31FUJ	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.24389991329770933	[521]	[517]	-2	hSpCas9	negative selection	10961729
96137574	96137597	2	-	28162770	P31FUJ	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.8331947457051407	[281]	[185]	-6	hSpCas9	negative selection	10961730
96134032	96134055	2	+	28162770	P31FUJ	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-4.320265045664717	[16]	[0]	-9	hSpCas9	negative selection	10961731
96133992	96134015	2	-	28162770	P31FUJ	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-1.0292688103292469	[32]	[18]	-6	hSpCas9	negative selection	10961732
96129908	96129931	2	+	28162770	P31FUJ	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.31589782017784085	[267]	[252]	-3	hSpCas9	negative selection	10961733
96129875	96129898	2	-	28162770	P31FUJ	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.34122466430036397	[220]	[204]	-3	hSpCas9	negative selection	10961734
96129837	96129860	2	-	28162770	P31FUJ	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.34606009677035965	[236]	[353]	4	hSpCas9	negative selection	10961735
96138390	96138413	2	+	28162770	P31FUJ	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.1619808672246818	[158]	[166]	-1	hSpCas9	negative selection	10961736
96133510	96133533	2	+	28162770	OCIAML5	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.5957268176042116	[71]	[85]	-4	hSpCas9	negative selection	11131093
96137661	96137684	2	+	28162770	OCIAML5	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	-0.6988203105683152	[115]	[128]	-4	hSpCas9	negative selection	11131094
96137588	96137611	2	+	28162770	OCIAML5	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.4050186766825321	[233]	[318]	-3	hSpCas9	negative selection	11131095
96137574	96137597	2	-	28162770	OCIAML5	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.30296421527862105	[118]	[264]	2	hSpCas9	negative selection	11131096
96134032	96134055	2	+	28162770	OCIAML5	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	0.19855950220597096	[13]	[28]	1	hSpCas9	negative selection	11131097
96133992	96134015	2	-	28162770	OCIAML5	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	0.437440046330988	[17]	[43]	4	hSpCas9	negative selection	11131098
96129908	96129931	2	+	28162770	OCIAML5	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.38473456414294016	[148]	[205]	-3	hSpCas9	negative selection	11131099
96129875	96129898	2	-	28162770	OCIAML5	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.6944217820425236	[75]	[221]	6	hSpCas9	negative selection	11131100
96129837	96129860	2	-	28162770	OCIAML5	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.780201644635516	[109]	[340]	6	hSpCas9	negative selection	11131101
96138390	96138413	2	+	28162770	OCIAML5	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.14039975645059535	[95]	[190]	1	hSpCas9	negative selection	11131102
96133510	96133533	2	+	28162770	EOL1	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	0.02317580429825028	[423]	[226]	0	hSpCas9	negative selection	11300459
96137661	96137684	2	+	28162770	EOL1	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.16966026940706608	[242]	[143]	1	hSpCas9	negative selection	11300460
96137588	96137611	2	+	28162770	EOL1	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.4380223078141736	[863]	[335]	-3	hSpCas9	negative selection	11300461
96137574	96137597	2	-	28162770	EOL1	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.34277354848042574	[451]	[301]	3	hSpCas9	negative selection	11300462
96134032	96134055	2	+	28162770	EOL1	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	0.6615133657367407	[17]	[14]	6	hSpCas9	negative selection	11300463
96133992	96134015	2	-	28162770	EOL1	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	0.2685021727878958	[51]	[32]	2	hSpCas9	negative selection	11300464
96129908	96129931	2	+	28162770	EOL1	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	-0.4411017007461458	[334]	[129]	-3	hSpCas9	negative selection	11300465
96129875	96129898	2	-	28162770	EOL1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-1.4042339943578903	[210]	[41]	-7	hSpCas9	negative selection	11300466
96129837	96129860	2	-	28162770	EOL1	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.24307728999603193	[254]	[158]	2	hSpCas9	negative selection	11300467
96138390	96138413	2	+	28162770	EOL1	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.8828071504870698	[195]	[55]	-6	hSpCas9	negative selection	11300468
96133510	96133533	2	+	28162770	MOLM13	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.01753744562566298	[300]	[214]	0	hSpCas9	negative selection	11469825
96137661	96137684	2	+	28162770	MOLM13	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	-0.1566014833632149	[221]	[143]	-1	hSpCas9	negative selection	11469826
96137588	96137611	2	+	28162770	MOLM13	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.19876270239516103	[616]	[511]	1	hSpCas9	negative selection	11469827
96137574	96137597	2	-	28162770	MOLM13	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.28004733044263036	[439]	[261]	-2	hSpCas9	negative selection	11469828
96134032	96134055	2	+	28162770	MOLM13	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-3.339465540513026	[13]	[0]	-8	hSpCas9	negative selection	11469829
96133992	96134015	2	-	28162770	MOLM13	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	1.8193617520459564	[28]	[73]	9	hSpCas9	negative selection	11469830
96129908	96129931	2	+	28162770	MOLM13	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.7393115728710918	[342]	[413]	5	hSpCas9	negative selection	11469831
96129875	96129898	2	-	28162770	MOLM13	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.7653413844357342	[213]	[262]	6	hSpCas9	negative selection	11469832
96129837	96129860	2	-	28162770	MOLM13	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.3707482231340472	[214]	[200]	2	hSpCas9	negative selection	11469833
96138390	96138413	2	+	28162770	MOLM13	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.2349096094704356	[152]	[93]	-1	hSpCas9	negative selection	11469834
96133510	96133533	2	+	28162770	HEL	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.6931284538448791	[259]	[102]	-4	hSpCas9	negative selection	11639191
96137661	96137684	2	+	28162770	HEL	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.6048706464099138	[192]	[187]	5	hSpCas9	negative selection	11639192
96137588	96137611	2	+	28162770	HEL	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.9240415297631497	[496]	[603]	7	hSpCas9	negative selection	11639193
96137574	96137597	2	-	28162770	HEL	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.7962840902538125	[373]	[415]	7	hSpCas9	negative selection	11639194
96134032	96134055	2	+	28162770	HEL	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-0.001117357774367722	[24]	[15]	0	hSpCas9	negative selection	11639195
96133992	96134015	2	-	28162770	HEL	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	1.872220678123124	[28]	[67]	9	hSpCas9	negative selection	11639196
96129908	96129931	2	+	28162770	HEL	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.48008849435579837	[271]	[242]	4	hSpCas9	negative selection	11639197
96129875	96129898	2	-	28162770	HEL	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.5196804355960187	[158]	[145]	4	hSpCas9	negative selection	11639198
96129837	96129860	2	-	28162770	HEL	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	0.1152266034631006	[159]	[110]	0	hSpCas9	negative selection	11639199
96138390	96138413	2	+	28162770	HEL	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.26872449339798565	[157]	[83]	-2	hSpCas9	negative selection	11639200
96133510	96133533	2	+	28162770	MV411	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-1.0445890583907254	[190]	[77]	-6	hSpCas9	negative selection	11808557
96137661	96137684	2	+	28162770	MV411	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.45275645876028164	[169]	[195]	4	hSpCas9	negative selection	11808558
96137588	96137611	2	+	28162770	MV411	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.06758467441085236	[400]	[353]	0	hSpCas9	negative selection	11808559
96137574	96137597	2	-	28162770	MV411	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.7435907845460753	[267]	[377]	6	hSpCas9	negative selection	11808560
96134032	96134055	2	+	28162770	MV411	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	1.4953650642263607	[7]	[18]	9	hSpCas9	negative selection	11808561
96133992	96134015	2	-	28162770	MV411	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-0.44444015385489255	[20]	[12]	-3	hSpCas9	negative selection	11808562
96129908	96129931	2	+	28162770	MV411	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.6758955658239407	[213]	[287]	6	hSpCas9	negative selection	11808563
96129875	96129898	2	-	28162770	MV411	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.0215561433664474	[137]	[117]	0	hSpCas9	negative selection	11808564
96129837	96129860	2	-	28162770	MV411	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	-0.0054827772868213664	[198]	[166]	0	hSpCas9	negative selection	11808565
96138390	96138413	2	+	28162770	MV411	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.9130185117122159	[115]	[183]	7	hSpCas9	negative selection	11808566
96133510	96133533	2	+	28162770	MONOMAC1	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-1.292961267058089	[170]	[79]	-7	hSpCas9	negative selection	11977923
96137661	96137684	2	+	28162770	MONOMAC1	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	0.20540061543965665	[114]	[151]	2	hSpCas9	negative selection	11977924
96137588	96137611	2	+	28162770	MONOMAC1	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	-0.020539191693754955	[291]	[329]	0	hSpCas9	negative selection	11977925
96137574	96137597	2	-	28162770	MONOMAC1	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	0.5875346793537626	[154]	[266]	6	hSpCas9	negative selection	11977926
96134032	96134055	2	+	28162770	MONOMAC1	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-1.4771447662522887	[16]	[6]	-8	hSpCas9	negative selection	11977927
96133992	96134015	2	-	28162770	MONOMAC1	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	1.1248912478278088	[19]	[49]	8	hSpCas9	negative selection	11977928
96129908	96129931	2	+	28162770	MONOMAC1	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.1227201487861814	[132]	[165]	1	hSpCas9	negative selection	11977929
96129875	96129898	2	-	28162770	MONOMAC1	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.31243545407733914	[84]	[120]	3	hSpCas9	negative selection	11977930
96129837	96129860	2	-	28162770	MONOMAC1	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	-0.5068921096463411	[118]	[95]	-4	hSpCas9	negative selection	11977931
96138390	96138413	2	+	28162770	MONOMAC1	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.3225677291434127	[83]	[76]	-3	hSpCas9	negative selection	11977932
96133510	96133533	2	+	28162770	OCIAML2	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	0.34528711031886694	[23]	[168]	3	hSpCas9	negative selection	12147289
96137661	96137684	2	+	28162770	OCIAML2	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	-0.15984228795999939	[25]	[128]	-1	hSpCas9	negative selection	12147290
96137588	96137611	2	+	28162770	OCIAML2	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.5091922928202083	[62]	[496]	5	hSpCas9	negative selection	12147291
96137574	96137597	2	-	28162770	OCIAML2	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.2709574804057969	[63]	[293]	-2	hSpCas9	negative selection	12147292
96134032	96134055	2	+	28162770	OCIAML2	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	0.6168330160081781	[3]	[33]	6	hSpCas9	negative selection	12147293
96133992	96134015	2	-	28162770	OCIAML2	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	1.2842576769213072	[1]	[26]	9	hSpCas9	negative selection	12147294
96129908	96129931	2	+	28162770	OCIAML2	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.14828000740233271	[48]	[300]	1	hSpCas9	negative selection	12147295
96129875	96129898	2	-	28162770	OCIAML2	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	-0.32519938572059737	[32]	[145]	-3	hSpCas9	negative selection	12147296
96129837	96129860	2	-	28162770	OCIAML2	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	-0.7527730540236595	[37]	[124]	-5	hSpCas9	negative selection	12147297
96138390	96138413	2	+	28162770	OCIAML2	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	0.19233518748026812	[20]	[132]	1	hSpCas9	negative selection	12147298
96133510	96133533	2	+	28162770	OCIAML3	viability	GAGCCTCCAGGATGACCTGGCGG	ASTL	ENSG00000188886	-0.1896173852448279	[50]	[134]	-1	hSpCas9	negative selection	12316655
96137661	96137684	2	+	28162770	OCIAML3	viability	CCTGCGCAGCTGGAGGCCAGGGG	ASTL	ENSG00000188886	1.5687752918741293	[44]	[402]	9	hSpCas9	negative selection	12316656
96137588	96137611	2	+	28162770	OCIAML3	viability	AGGAATGTCCTTGTCCCCGGAGG	ASTL	ENSG00000188886	0.5467173846695748	[121]	[537]	5	hSpCas9	negative selection	12316657
96137574	96137597	2	-	28162770	OCIAML3	viability	GACATTCCTGCAATTAACCAAGG	ASTL	ENSG00000188886	-0.27896593102204087	[83]	[208]	-2	hSpCas9	negative selection	12316658
96134032	96134055	2	+	28162770	OCIAML3	viability	GGTTGCTGACAGCAGTCGGAAGG	ASTL	ENSG00000188886	-2.272079545436801	[7]	[4]	-8	hSpCas9	negative selection	12316659
96133992	96134015	2	-	28162770	OCIAML3	viability	GGGTGGTAGTGGTGTCGTGGAGG	ASTL	ENSG00000188886	-1.2314375609394546	[6]	[8]	-7	hSpCas9	negative selection	12316660
96129908	96129931	2	+	28162770	OCIAML3	viability	GCTGGCCGATGTGGACACTGGGG	ASTL	ENSG00000188886	0.1687419796122758	[60]	[206]	1	hSpCas9	negative selection	12316661
96129875	96129898	2	-	28162770	OCIAML3	viability	GAGTGCCTCGGACATCACCCGGG	ASTL	ENSG00000188886	0.7476837093846291	[28]	[146]	6	hSpCas9	negative selection	12316662
96129837	96129860	2	-	28162770	OCIAML3	viability	GCTGCAGCCCAAGTGGCCCCAGG	ASTL	ENSG00000188886	1.0295761544243005	[42]	[264]	8	hSpCas9	negative selection	12316663
96138390	96138413	2	+	28162770	OCIAML3	viability	GAGAGCAGACCCAGCACCCAAGG	ASTL	ENSG00000188886	-0.50911874273765	[32]	[69]	-4	hSpCas9	negative selection	12316664