Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 89849
• Symbol: ATG16L2
• Description: autophagy related 16 like 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ATG16L2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
72822092	72822115	11	+	26472758	Jiyoye	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-6.035768114342855	[86]	[0]	-9	hSpCas9	negative selection	11775
72824074	72824097	11	-	26472758	Jiyoye	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	1.319712540255534	[33]	[63]	7	hSpCas9	negative selection	11776
72825310	72825333	11	-	26472758	Jiyoye	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.05289191330612608	[371]	[290]	0	hSpCas9	negative selection	11777
72817801	72817824	11	+	26472758	Jiyoye	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	1.3173787111552275	[115]	[217]	7	hSpCas9	negative selection	11778
72821664	72821687	11	+	26472758	Jiyoye	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.8949692232200313	[86]	[121]	6	hSpCas9	negative selection	11779
72822113	72822136	11	+	26472758	Jiyoye	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.13471839732339685	[197]	[135]	-1	hSpCas9	negative selection	11780
72822268	72822291	11	+	26472758	Jiyoye	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	1.4375490305493923	[46]	[95]	8	hSpCas9	negative selection	11781
72822472	72822495	11	+	26472758	Jiyoye	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.21162457238806653	[70]	[61]	1	hSpCas9	negative selection	11782
72822493	72822516	11	+	26472758	Jiyoye	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.09031827616593302	[70]	[56]	0	hSpCas9	negative selection	11783
72822849	72822872	11	+	26472758	Jiyoye	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.8391356667367937	[222]	[93]	-5	hSpCas9	negative selection	11784
72822092	72822115	11	+	26472758	KBM7	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-1.02836349098544	[115,69]	[20,20]	-7	hSpCas9	negative selection	202893
72824074	72824097	11	-	26472758	KBM7	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.474461868151529	[346,337]	[204,241]	5	hSpCas9	negative selection	202894
72825310	72825333	11	-	26472758	KBM7	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	-0.3154011777621043	[1030,846]	[343,360]	-3	hSpCas9	negative selection	202895
72817801	72817824	11	+	26472758	KBM7	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.015278349668707003	[918,612]	[285,422]	0	hSpCas9	negative selection	202896
72821664	72821687	11	+	26472758	KBM7	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.1368504735543385	[320,337]	[225,122]	1	hSpCas9	negative selection	202897
72822113	72822136	11	+	26472758	KBM7	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.6474544479782978	[615,480]	[212,118]	-5	hSpCas9	negative selection	202898
72822268	72822291	11	+	26472758	KBM7	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	1.2179028931598996	[390,468]	[496,458]	9	hSpCas9	negative selection	202899
72822472	72822495	11	+	26472758	KBM7	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.866083315536478	[493,198]	[370,208]	8	hSpCas9	negative selection	202900
72822493	72822516	11	+	26472758	KBM7	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.2037601538875149	[302,412]	[228,169]	2	hSpCas9	negative selection	202901
72822849	72822872	11	+	26472758	KBM7	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.0645986094208465	[651,501]	[233,277]	0	hSpCas9	negative selection	202902
72822092	72822115	11	+	26472758	Raji	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	3.609883875902783	[5]	[16]	9	hSpCas9	negative selection	394011
72824074	72824097	11	-	26472758	Raji	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	-0.836907032040113	[253]	[32]	-6	hSpCas9	negative selection	394012
72825310	72825333	11	-	26472758	Raji	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.7124116591488614	[475]	[180]	6	hSpCas9	negative selection	394013
72817801	72817824	11	+	26472758	Raji	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	-0.13596253553808213	[392]	[82]	-1	hSpCas9	negative selection	394014
72821664	72821687	11	+	26472758	Raji	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.3840928781044699	[174]	[52]	3	hSpCas9	negative selection	394015
72822113	72822136	11	+	26472758	Raji	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.31215535614018497	[213]	[39]	-3	hSpCas9	negative selection	394016
72822268	72822291	11	+	26472758	Raji	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.01992069412326014	[169]	[39]	0	hSpCas9	negative selection	394017
72822472	72822495	11	+	26472758	Raji	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.47363178083089374	[364]	[60]	-4	hSpCas9	negative selection	394018
72822493	72822516	11	+	26472758	Raji	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-1.6999713866840047	[223]	[15]	-8	hSpCas9	negative selection	394019
72822849	72822872	11	+	26472758	Raji	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.26155446550135963	[265]	[73]	2	hSpCas9	negative selection	394020
72822092	72822115	11	+	26472758	K562	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-2.8373753634972	[126]	[14]	-8	hSpCas9	negative selection	585129
72824074	72824097	11	-	26472758	K562	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	-0.15767971590489882	[258]	[195]	-1	hSpCas9	negative selection	585130
72825310	72825333	11	-	26472758	K562	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.4416105948777521	[593]	[680]	3	hSpCas9	negative selection	585131
72817801	72817824	11	+	26472758	K562	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	-0.6651659771113348	[602]	[320]	-4	hSpCas9	negative selection	585132
72821664	72821687	11	+	26472758	K562	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.6441663559206956	[331]	[437]	5	hSpCas9	negative selection	585133
72822113	72822136	11	+	26472758	K562	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-2.3287086366177396	[606]	[101]	-8	hSpCas9	negative selection	585134
72822268	72822291	11	+	26472758	K562	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.046355635691739686	[342]	[298]	0	hSpCas9	negative selection	585135
72822472	72822495	11	+	26472758	K562	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.1299767871150509	[349]	[269]	-1	hSpCas9	negative selection	585136
72822493	72822516	11	+	26472758	K562	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.21014713579903435	[332]	[242]	-1	hSpCas9	negative selection	585137
72822849	72822872	11	+	26472758	K562	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.2349790317801413	[459]	[456]	1	hSpCas9	negative selection	585138
72814514	72814537	11	+	26627737	DLD1	viability	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.5535559763653128	[1571]	[831,555,761]	5	hSpCas9	negative selection	780918
72816822	72816845	11	-	26627737	DLD1	viability	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.7001193215763618	[547]	[95,139,84]	-6	hSpCas9	negative selection	780919
72817738	72817761	11	+	26627737	DLD1	viability	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.4035910876457208	[619]	[184,130,125]	-4	hSpCas9	negative selection	780920
72822221	72822244	11	-	26627737	DLD1	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.295627824108353	[174]	[78,37,80]	3	hSpCas9	negative selection	780921
72822466	72822489	11	+	26627737	DLD1	viability	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.0658088930991012	[801]	[196,245,270]	0	hSpCas9	negative selection	780922
72824824	72824847	11	-	26627737	DLD1	viability	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.35417792886660815	[626]	[269,388,118]	3	hSpCas9	negative selection	780923
72814514	72814537	11	+	26627737	GBM cells	viability after 5 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.33964698866859333	[945]	[590,692]	5	hSpCas9	negative selection	863233
72816822	72816845	11	-	26627737	GBM cells	viability after 5 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.0488719206733763	[406]	[119,90]	-9	hSpCas9	negative selection	863234
72817738	72817761	11	+	26627737	GBM cells	viability after 5 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.2647383996858532	[245]	[158,157]	4	hSpCas9	negative selection	863235
72822221	72822244	11	-	26627737	GBM cells	viability after 5 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.291231297664446	[63]	[62,20]	4	hSpCas9	negative selection	863236
72822466	72822489	11	+	26627737	GBM cells	viability after 5 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.24530805458775318	[451]	[172,235]	-4	hSpCas9	negative selection	863237
72824824	72824847	11	-	26627737	GBM cells	viability after 5 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.0010191700103920898	[361]	[230,156]	0	hSpCas9	negative selection	863238
72814514	72814537	11	+	26627737	GBM cells	viability after 13 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.23714547953242082	[945]	[631,582]	3	hSpCas9	negative selection	945548
72816822	72816845	11	-	26627737	GBM cells	viability after 13 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.0285586459610747	[406]	[126,92]	-8	hSpCas9	negative selection	945549
72817738	72817761	11	+	26627737	GBM cells	viability after 13 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.6248011857596095	[245]	[255,164]	7	hSpCas9	negative selection	945550
72822221	72822244	11	-	26627737	GBM cells	viability after 13 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.5603407699792091	[63]	[48,52]	7	hSpCas9	negative selection	945551
72822466	72822489	11	+	26627737	GBM cells	viability after 13 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.06472220294745634	[451]	[239,229]	-1	hSpCas9	negative selection	945552
72824824	72824847	11	-	26627737	GBM cells	viability after 13 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.5268519812422041	[361]	[164,112]	-6	hSpCas9	negative selection	945553
72814514	72814537	11	+	26627737	GBM cells	viability after 21 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.7911894736408782	[945]	[903,875]	7	hSpCas9	negative selection	1027863
72816822	72816845	11	-	26627737	GBM cells	viability after 21 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.910634842345388	[406]	[149,87]	-7	hSpCas9	negative selection	1027864
72817738	72817761	11	+	26627737	GBM cells	viability after 21 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.5675811522965973	[245]	[85,93]	-5	hSpCas9	negative selection	1027865
72822221	72822244	11	-	26627737	GBM cells	viability after 21 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-1.0618351287661567	[63]	[12,19]	-7	hSpCas9	negative selection	1027866
72822466	72822489	11	+	26627737	GBM cells	viability after 21 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.5492332992318201	[451]	[374,344]	5	hSpCas9	negative selection	1027867
72824824	72824847	11	-	26627737	GBM cells	viability after 21 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.13021960380440267	[361]	[232,198]	1	hSpCas9	negative selection	1027868
72814514	72814537	11	+	26627737	RPE1	viability after 9 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.46680348632147606	[2520]	[1071,1114]	3	hSpCas9	negative selection	1110178
72816822	72816845	11	-	26627737	RPE1	viability after 9 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.4952489357871337	[1872]	[269,127]	-8	hSpCas9	negative selection	1110179
72817738	72817761	11	+	26627737	RPE1	viability after 9 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.18619284321203217	[1006]	[297,436]	1	hSpCas9	negative selection	1110180
72822221	72822244	11	-	26627737	RPE1	viability after 9 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-1.0788638245669233	[395]	[59,56]	-7	hSpCas9	negative selection	1110181
72822466	72822489	11	+	26627737	RPE1	viability after 9 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.9370660545849349	[909]	[341,807]	6	hSpCas9	negative selection	1110182
72824824	72824847	11	-	26627737	RPE1	viability after 9 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-1.2192486413128953	[1615]	[239,187]	-7	hSpCas9	negative selection	1110183
72814514	72814537	11	+	26627737	RPE1	viability after 12 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.42809064993640744	[2520]	[937,882]	3	hSpCas9	negative selection	1192493
72816822	72816845	11	-	26627737	RPE1	viability after 12 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.4572981510732272	[1872]	[293,65]	-7	hSpCas9	negative selection	1192494
72817738	72817761	11	+	26627737	RPE1	viability after 12 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.2789460378645234	[1006]	[404,246]	2	hSpCas9	negative selection	1192495
72822221	72822244	11	-	26627737	RPE1	viability after 12 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.14014759018763667	[395]	[131,58]	-1	hSpCas9	negative selection	1192496
72822466	72822489	11	+	26627737	RPE1	viability after 12 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	1.0207511865065255	[909]	[344,655]	6	hSpCas9	negative selection	1192497
72824824	72824847	11	-	26627737	RPE1	viability after 12 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.7516718713617276	[1615]	[201,316]	-5	hSpCas9	negative selection	1192498
72814514	72814537	11	+	26627737	RPE1	viability after 15 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.32064185362489495	[2520]	[967,815]	2	hSpCas9	negative selection	1274808
72816822	72816845	11	-	26627737	RPE1	viability after 15 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.3667570886009275	[1872]	[348,66]	-7	hSpCas9	negative selection	1274809
72817738	72817761	11	+	26627737	RPE1	viability after 15 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.41200689437974036	[1006]	[236,191]	-3	hSpCas9	negative selection	1274810
72822221	72822244	11	-	26627737	RPE1	viability after 15 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.3862092595650054	[395]	[101,69]	-2	hSpCas9	negative selection	1274811
72822466	72822489	11	+	26627737	RPE1	viability after 15 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.8175389718522924	[909]	[246,652]	5	hSpCas9	negative selection	1274812
72824824	72824847	11	-	26627737	RPE1	viability after 15 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.8833327622886121	[1615]	[229,264]	-5	hSpCas9	negative selection	1274813
72814514	72814537	11	+	26627737	RPE1	viability after 18 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.2982934869618188	[2520]	[795,879]	2	hSpCas9	negative selection	1357123
72816822	72816845	11	-	26627737	RPE1	viability after 18 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.068662703500969	[1872]	[327,147]	-6	hSpCas9	negative selection	1357124
72817738	72817761	11	+	26627737	RPE1	viability after 18 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.19423925510145051	[1006]	[366,250]	1	hSpCas9	negative selection	1357125
72822221	72822244	11	-	26627737	RPE1	viability after 18 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.6253071999216618	[395]	[174,153]	4	hSpCas9	negative selection	1357126
72822466	72822489	11	+	26627737	RPE1	viability after 18 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.9532686248536203	[909]	[227,739]	5	hSpCas9	negative selection	1357127
72824824	72824847	11	-	26627737	RPE1	viability after 18 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.6072142921900183	[1615]	[250,323]	-4	hSpCas9	negative selection	1357128
72814514	72814537	11	+	26627737	HeLa	viability after 8 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.2584096739069328	[1338]	[753,898,466]	2	hSpCas9	negative selection	1439438
72816822	72816845	11	-	26627737	HeLa	viability after 8 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.8757942925817963	[404]	[157,6,133]	-7	hSpCas9	negative selection	1439439
72817738	72817761	11	+	26627737	HeLa	viability after 8 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.7030074949366658	[312]	[184,367,111]	6	hSpCas9	negative selection	1439440
72822221	72822244	11	-	26627737	HeLa	viability after 8 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.6594943213449	[191]	[29,1,116]	-6	hSpCas9	negative selection	1439441
72822466	72822489	11	+	26627737	HeLa	viability after 8 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.3623956501143578	[716]	[573,320,349]	3	hSpCas9	negative selection	1439442
72824824	72824847	11	-	26627737	HeLa	viability after 8 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.360675214452326	[269]	[273,118,90]	3	hSpCas9	negative selection	1439443
72814514	72814537	11	+	26627737	HeLa	viability after 12 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.24605462952869273	[1338]	[651,756,548]	2	hSpCas9	negative selection	1521753
72816822	72816845	11	-	26627737	HeLa	viability after 12 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-2.5969992205004746	[404]	[2,67,6]	-9	hSpCas9	negative selection	1521754
72817738	72817761	11	+	26627737	HeLa	viability after 12 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.6953627359573183	[312]	[305,163,165]	5	hSpCas9	negative selection	1521755
72822221	72822244	11	-	26627737	HeLa	viability after 12 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-1.0827140465023053	[191]	[23,27,60]	-7	hSpCas9	negative selection	1521756
72822466	72822489	11	+	26627737	HeLa	viability after 12 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.8503390920115693	[716]	[53,294,126]	-7	hSpCas9	negative selection	1521757
72824824	72824847	11	-	26627737	HeLa	viability after 12 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.8687860749566904	[269]	[258,164,192]	6	hSpCas9	negative selection	1521758
72814514	72814537	11	+	26627737	HeLa	viability after 15 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.23521154107630204	[1338]	[651,857,395]	2	hSpCas9	negative selection	1604068
72816822	72816845	11	-	26627737	HeLa	viability after 15 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.6004293322920854	[404]	[62,152,110]	-5	hSpCas9	negative selection	1604069
72817738	72817761	11	+	26627737	HeLa	viability after 15 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.9623557787683347	[312]	[269,365,96]	7	hSpCas9	negative selection	1604070
72822221	72822244	11	-	26627737	HeLa	viability after 15 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.3882886891303057	[191]	[29,35,117]	-3	hSpCas9	negative selection	1604071
72822466	72822489	11	+	26627737	HeLa	viability after 15 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.19845934099640583	[716]	[239,296,223]	-2	hSpCas9	negative selection	1604072
72824824	72824847	11	-	26627737	HeLa	viability after 15 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.24740663147887132	[269]	[52,87,140]	-2	hSpCas9	negative selection	1604073
72814514	72814537	11	+	26627737	HeLa	viability after 18 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.25720484893154394	[1338]	[444,724,395]	2	hSpCas9	negative selection	1686383
72816822	72816845	11	-	26627737	HeLa	viability after 18 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.6060417164422373	[404]	[41,125,110]	-5	hSpCas9	negative selection	1686384
72817738	72817761	11	+	26627737	HeLa	viability after 18 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.9971609209957539	[312]	[192,302,96]	7	hSpCas9	negative selection	1686385
72822221	72822244	11	-	26627737	HeLa	viability after 18 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.4282841480343138	[191]	[15,30,117]	-4	hSpCas9	negative selection	1686386
72822466	72822489	11	+	26627737	HeLa	viability after 18 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.23319491149102878	[716]	[149,244,223]	-2	hSpCas9	negative selection	1686387
72824824	72824847	11	-	26627737	HeLa	viability after 18 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.25587619420349694	[269]	[35,70,140]	-2	hSpCas9	negative selection	1686388
72814514	72814537	11	+	26627737	HCT116	viability after 6 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	-0.25201053611291746	[2264]	[405,239]	-1	hSpCas9	negative selection	1768698
72816822	72816845	11	-	26627737	HCT116	viability after 6 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	0.26544608100723266	[637]	[97,132]	1	hSpCas9	negative selection	1768699
72817738	72817761	11	+	26627737	HCT116	viability after 6 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.018550396371779868	[649]	[263,14]	0	hSpCas9	negative selection	1768700
72822221	72822244	11	-	26627737	HCT116	viability after 6 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-3.340435043767443	[483]	[2,9]	-9	hSpCas9	negative selection	1768701
72822466	72822489	11	+	26627737	HCT116	viability after 6 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.7320911289526164	[1039]	[297,256]	4	hSpCas9	negative selection	1768702
72824824	72824847	11	-	26627737	HCT116	viability after 6 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	1.2967282884661155	[659]	[455,143]	7	hSpCas9	negative selection	1768703
72814514	72814537	11	+	26627737	HCT116	viability after 8 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.35844470753739266	[1104]	[750,700,887]	4	hSpCas9	negative selection	1851013
72816822	72816845	11	-	26627737	HCT116	viability after 8 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.8296235079623522	[514]	[154,168,154]	-8	hSpCas9	negative selection	1851014
72817738	72817761	11	+	26627737	HCT116	viability after 8 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.2920294069203669	[261]	[139,243,145]	3	hSpCas9	negative selection	1851015
72822221	72822244	11	-	26627737	HCT116	viability after 8 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.2867388320108277	[137]	[35,43,105]	-3	hSpCas9	negative selection	1851016
72822466	72822489	11	+	26627737	HCT116	viability after 8 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.2531161124562514	[380]	[262,250,236]	3	hSpCas9	negative selection	1851017
72824824	72824847	11	-	26627737	HCT116	viability after 8 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.5328755439179017	[262]	[172,215,238]	5	hSpCas9	negative selection	1851018
72814514	72814537	11	+	26627737	HCT116	viability after 9 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	-0.1565027985615819	[2264]	[550,535]	-1	hSpCas9	negative selection	1933328
72816822	72816845	11	-	26627737	HCT116	viability after 9 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	0.5799414486275706	[637]	[195,300]	4	hSpCas9	negative selection	1933329
72817738	72817761	11	+	26627737	HCT116	viability after 9 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.060435218991578554	[649]	[290,67]	0	hSpCas9	negative selection	1933330
72822221	72822244	11	-	26627737	HCT116	viability after 9 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.04403968690407223	[483]	[245,29]	0	hSpCas9	negative selection	1933331
72822466	72822489	11	+	26627737	HCT116	viability after 9 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.2883384465396672	[1039]	[437,260]	2	hSpCas9	negative selection	1933332
72824824	72824847	11	-	26627737	HCT116	viability after 9 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.6685539317566025	[659]	[588,35]	5	hSpCas9	negative selection	1933333
72814514	72814537	11	+	26627737	HCT116	viability after 12 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.23134942112129675	[1104]	[672,685,686]	2	hSpCas9	negative selection	2015643
72816822	72816845	11	-	26627737	HCT116	viability after 12 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.8933054899326959	[514]	[144,178,113]	-7	hSpCas9	negative selection	2015644
72817738	72817761	11	+	26627737	HCT116	viability after 12 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.5186290342582978	[261]	[159,319,117]	5	hSpCas9	negative selection	2015645
72822221	72822244	11	-	26627737	HCT116	viability after 12 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.07302812417775395	[137]	[50,113,66]	0	hSpCas9	negative selection	2015646
72822466	72822489	11	+	26627737	HCT116	viability after 12 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.3839948070244629	[380]	[373,221,176]	4	hSpCas9	negative selection	2015647
72824824	72824847	11	-	26627737	HCT116	viability after 12 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.7979951261383291	[262]	[331,162,215]	7	hSpCas9	negative selection	2015648
72814514	72814537	11	+	26627737	HCT116	viability after 15 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.6700545501309398	[1104]	[1297,734,1030]	6	hSpCas9	negative selection	2097958
72816822	72816845	11	-	26627737	HCT116	viability after 15 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.496862527317334	[514]	[126,160,29]	-8	hSpCas9	negative selection	2097959
72817738	72817761	11	+	26627737	HCT116	viability after 15 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.0018854721158755583	[261]	[50,332,56]	0	hSpCas9	negative selection	2097960
72822221	72822244	11	-	26627737	HCT116	viability after 15 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.11623072844635196	[137]	[26,92,129]	1	hSpCas9	negative selection	2097961
72822466	72822489	11	+	26627737	HCT116	viability after 15 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.6263329953120829	[380]	[360,308,345]	6	hSpCas9	negative selection	2097962
72824824	72824847	11	-	26627737	HCT116	viability after 15 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.5482656161023489	[262]	[266,244,156]	5	hSpCas9	negative selection	2097963
72814514	72814537	11	+	26627737	HCT116	viability after 18 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.3374414403276882	[1104]	[822,553,654]	3	hSpCas9	negative selection	2180273
72816822	72816845	11	-	26627737	HCT116	viability after 18 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.7733927220625154	[514]	[47,52,120]	-8	hSpCas9	negative selection	2180274
72817738	72817761	11	+	26627737	HCT116	viability after 18 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.46184926946774385	[261]	[118,285,107]	4	hSpCas9	negative selection	2180275
72822221	72822244	11	-	26627737	HCT116	viability after 18 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.02380511054210044	[137]	[18,57,122]	0	hSpCas9	negative selection	2180276
72822466	72822489	11	+	26627737	HCT116	viability after 18 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.001249605939299403	[380]	[200,177,172]	0	hSpCas9	negative selection	2180277
72824824	72824847	11	-	26627737	HCT116	viability after 18 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.7152910210527103	[262]	[240,231,148]	6	hSpCas9	negative selection	2180278
72814482	72814506	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CGCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.47470695963283205	[2179,1579,1703]	[0,0,0]	1	hSpCas9	positive selection	2380554
72814482	72814506	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CGCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.47470695963283205	[2179,1579,1703]	[0,0,0]	1	hSpCas9	positive selection	2380555
72814493	72814515	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CCACATCGTGCGGCAGCTGCGG	ATG16L2	ENSG00000168010	2.3406184212133136	[3732,2881,2874]	[0,0,16]	5	hSpCas9	positive selection	2380556
72814493	72814515	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CCACATCGTGCGGCAGCTGCGG	ATG16L2	ENSG00000168010	2.3406184212133136	[3732,2881,2874]	[0,0,16]	5	hSpCas9	positive selection	2380557
72814512	72814537	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CGGCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	-1.580822467509952	[8358,6855,7445]	[0,0,0]	-9	hSpCas9	positive selection	2380558
72814512	72814537	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CGGCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	-1.580822467509952	[8358,6855,7445]	[0,0,0]	-9	hSpCas9	positive selection	2380559
72814482	72814506	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.47464896999606015	[2179,1579,1703]	[0,0,0]	1	hSpCas9	positive selection	2381664
72814482	72814506	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.47464896999606015	[2179,1579,1703]	[0,0,0]	1	hSpCas9	positive selection	2381665
72814493	72814515	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCACATCGTGCGGCAGCTGCGG	ATG16L2	ENSG00000168010	-0.322571993468188	[3732,2881,2874]	[0,0,0]	-4	hSpCas9	positive selection	2381666
72814493	72814515	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCACATCGTGCGGCAGCTGCGG	ATG16L2	ENSG00000168010	-0.322571993468188	[3732,2881,2874]	[0,0,0]	-4	hSpCas9	positive selection	2381667
72814512	72814537	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGGCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	3.856563994291689	[8358,6855,7445]	[127,0,0]	6	hSpCas9	positive selection	2381668
72814512	72814537	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CGGCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	3.856563994291689	[8358,6855,7445]	[127,0,0]	6	hSpCas9	positive selection	2381669
72814314	72814337	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATCCCCGGCTTGTCCCAAGAGGG	ATG16L2	ENSG00000168010	0.6625191784842466	[269,200]	[24,142]	3	dCas9-VP64	positive selection	2461314
72814314	72814337	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATCCCCGGCTTGTCCCAAGAGGG	ATG16L2	ENSG00000168010	-0.43894436643864165	[191,200]	[60,33]	-4	dCas9-VP64	positive selection	2556569
72822262	72822285	11	-	27260157	DLD1	viability	CTCGTTGCGCAGGTTGCGCTCGG	ATG16L2	ENSG00000168010	-0.213125498727899	[]	[]	-2	hSpCas9	negative selection	2573691
72826737	72826760	11	+	27260157	DLD1	viability	CTGCCAAATTCAAGCTAACGAGG	ATG16L2	ENSG00000168010	0.88189887896106	[]	[]	9	hSpCas9	negative selection	2575779
72825317	72825340	11	+	27260157	DLD1	viability	GAGGTCAATGCTGTTCGTTTTGG	ATG16L2	ENSG00000168010	-0.290693404414491	[]	[]	-2	hSpCas9	negative selection	2577716
72825298	72825321	11	+	27260157	DLD1	viability	ACAGGATGCCCACCTCTCTGAGG	ATG16L2	ENSG00000168010	0.643742012187185	[]	[]	8	hSpCas9	negative selection	2581113
72814544	72814567	11	-	27260157	DLD1	viability	CACAGGCCGGCACCAGCTCCAGG	ATG16L2	ENSG00000168010	0.103684585837351	[]	[]	3	hSpCas9	negative selection	2585702
72826780	72826803	11	-	27260157	DLD1	viability	ACTCCTTCACTGTCCGGTCGCGG	ATG16L2	ENSG00000168010	0.130195351685401	[]	[]	3	hSpCas9	negative selection	2586258
72824769	72824792	11	-	27260157	DLD1	viability	GATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.944105555935626	[]	[]	9	hSpCas9	negative selection	2604653
72814471	72814494	11	-	27260157	DLD1	viability	GCGTTTCCAGCGCGCTGCGGGGG	ATG16L2	ENSG00000168010	-0.203533639832521	[]	[]	-1	hSpCas9	negative selection	2614393
72822849	72822872	11	+	27260157	DLD1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-1.09006032941541	[]	[]	-7	hSpCas9	negative selection	2616381
72826767	72826790	11	+	27260157	DLD1	viability	CAGTGACTGGGAGCCGCGACCGG	ATG16L2	ENSG00000168010	0.262849355322667	[]	[]	4	hSpCas9	negative selection	2616684
72822221	72822244	11	-	27260157	DLD1	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.0973198642261586	[]	[]	0	hSpCas9	negative selection	2617562
72826762	72826785	11	-	27260157	DLD1	viability	CGCGGCTCCCAGTCACTGCCTGG	ATG16L2	ENSG00000168010	0.18433467847068	[]	[]	3	hSpCas9	negative selection	2619123
72826807	72826830	11	-	27260157	DLD1	viability	GCTCACAATAGGCACGGCCGAGG	ATG16L2	ENSG00000168010	0.573644469188899	[]	[]	8	hSpCas9	negative selection	2641072
72826777	72826800	11	+	27260157	DLD1	viability	GAGCCGCGACCGGACAGTGAAGG	ATG16L2	ENSG00000168010	0.657223967237027	[]	[]	8	hSpCas9	negative selection	2643809
72822268	72822291	11	+	27260157	DLD1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.0936476360609344	[]	[]	0	hSpCas9	negative selection	2644855
72817780	72817803	11	-	27260157	DLD1	viability	GTGCGACCAGTGATGGGACTTGG	ATG16L2	ENSG00000168010	-0.0933161012641951	[]	[]	0	hSpCas9	negative selection	2645278
72824811	72824834	11	-	27260157	DLD1	viability	CTGAGCCCGGGTAGGAAGTCGGG	ATG16L2	ENSG00000168010	0.122871707566765	[]	[]	3	hSpCas9	negative selection	2647084
72824805	72824828	11	+	27260157	DLD1	viability	TGGCTGCCCGACTTCCTACCCGG	ATG16L2	ENSG00000168010	0.784388078841946	[]	[]	8	hSpCas9	negative selection	2649245
72822262	72822285	11	-	27260157	HT1080	viability	CTCGTTGCGCAGGTTGCGCTCGG	ATG16L2	ENSG00000168010	-0.323859059726982	[]	[]	-7	hSpCas9	negative selection	2649821
72826737	72826760	11	+	27260157	HT1080	viability	CTGCCAAATTCAAGCTAACGAGG	ATG16L2	ENSG00000168010	0.178953732947548	[]	[]	1	hSpCas9	negative selection	2651909
72825317	72825340	11	+	27260157	HT1080	viability	GAGGTCAATGCTGTTCGTTTTGG	ATG16L2	ENSG00000168010	0.0879360014194833	[]	[]	1	hSpCas9	negative selection	2653846
72825298	72825321	11	+	27260157	HT1080	viability	ACAGGATGCCCACCTCTCTGAGG	ATG16L2	ENSG00000168010	1.00529165477345	[]	[]	8	hSpCas9	negative selection	2657243
72814544	72814567	11	-	27260157	HT1080	viability	CACAGGCCGGCACCAGCTCCAGG	ATG16L2	ENSG00000168010	0.509297358203912	[]	[]	4	hSpCas9	negative selection	2661832
72826780	72826803	11	-	27260157	HT1080	viability	ACTCCTTCACTGTCCGGTCGCGG	ATG16L2	ENSG00000168010	0.182939832411443	[]	[]	1	hSpCas9	negative selection	2662388
72824769	72824792	11	-	27260157	HT1080	viability	GATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.283485155320999	[]	[]	2	hSpCas9	negative selection	2680783
72814471	72814494	11	-	27260157	HT1080	viability	GCGTTTCCAGCGCGCTGCGGGGG	ATG16L2	ENSG00000168010	-2.05404804299594	[]	[]	-9	hSpCas9	negative selection	2690523
72822849	72822872	11	+	27260157	HT1080	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.865017121994951	[]	[]	-8	hSpCas9	negative selection	2692511
72826767	72826790	11	+	27260157	HT1080	viability	CAGTGACTGGGAGCCGCGACCGG	ATG16L2	ENSG00000168010	0.414619063927352	[]	[]	4	hSpCas9	negative selection	2692814
72822221	72822244	11	-	27260157	HT1080	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	1.4131281194364	[]	[]	9	hSpCas9	negative selection	2693692
72826762	72826785	11	-	27260157	HT1080	viability	CGCGGCTCCCAGTCACTGCCTGG	ATG16L2	ENSG00000168010	0.266314304013051	[]	[]	2	hSpCas9	negative selection	2695253
72826807	72826830	11	-	27260157	HT1080	viability	GCTCACAATAGGCACGGCCGAGG	ATG16L2	ENSG00000168010	0.335580702307568	[]	[]	3	hSpCas9	negative selection	2717202
72826777	72826800	11	+	27260157	HT1080	viability	GAGCCGCGACCGGACAGTGAAGG	ATG16L2	ENSG00000168010	0.179162692461557	[]	[]	1	hSpCas9	negative selection	2719939
72822268	72822291	11	+	27260157	HT1080	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.232163495164082	[]	[]	0	hSpCas9	negative selection	2720985
72817780	72817803	11	-	27260157	HT1080	viability	GTGCGACCAGTGATGGGACTTGG	ATG16L2	ENSG00000168010	0.434079266509822	[]	[]	4	hSpCas9	negative selection	2721408
72824811	72824834	11	-	27260157	HT1080	viability	CTGAGCCCGGGTAGGAAGTCGGG	ATG16L2	ENSG00000168010	0.331564749265436	[]	[]	3	hSpCas9	negative selection	2723214
72824805	72824828	11	+	27260157	HT1080	viability	TGGCTGCCCGACTTCCTACCCGG	ATG16L2	ENSG00000168010	0.227736625038089	[]	[]	2	hSpCas9	negative selection	2725375
72822262	72822285	11	-	27260157	MKN45	viability	CTCGTTGCGCAGGTTGCGCTCGG	ATG16L2	ENSG00000168010	-0.0141854771474838	[]	[]	0	hSpCas9	negative selection	2725951
72826737	72826760	11	+	27260157	MKN45	viability	CTGCCAAATTCAAGCTAACGAGG	ATG16L2	ENSG00000168010	0.165443203818883	[]	[]	5	hSpCas9	negative selection	2728039
72825317	72825340	11	+	27260157	MKN45	viability	GAGGTCAATGCTGTTCGTTTTGG	ATG16L2	ENSG00000168010	-0.803665302271038	[]	[]	-7	hSpCas9	negative selection	2729976
72825298	72825321	11	+	27260157	MKN45	viability	ACAGGATGCCCACCTCTCTGAGG	ATG16L2	ENSG00000168010	0.262906654066553	[]	[]	5	hSpCas9	negative selection	2733373
72814544	72814567	11	-	27260157	MKN45	viability	CACAGGCCGGCACCAGCTCCAGG	ATG16L2	ENSG00000168010	0.00518671305575934	[]	[]	0	hSpCas9	negative selection	2737962
72826780	72826803	11	-	27260157	MKN45	viability	ACTCCTTCACTGTCCGGTCGCGG	ATG16L2	ENSG00000168010	-0.553153503283566	[]	[]	-6	hSpCas9	negative selection	2738518
72824769	72824792	11	-	27260157	MKN45	viability	GATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	-0.582777766557575	[]	[]	-6	hSpCas9	negative selection	2756913
72814471	72814494	11	-	27260157	MKN45	viability	GCGTTTCCAGCGCGCTGCGGGGG	ATG16L2	ENSG00000168010	-2.04285231018078	[]	[]	-9	hSpCas9	negative selection	2766653
72822849	72822872	11	+	27260157	MKN45	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-1.81605646581647	[]	[]	-9	hSpCas9	negative selection	2768641
72826767	72826790	11	+	27260157	MKN45	viability	CAGTGACTGGGAGCCGCGACCGG	ATG16L2	ENSG00000168010	0.472110547479288	[]	[]	6	hSpCas9	negative selection	2768944
72822221	72822244	11	-	27260157	MKN45	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.207653173513953	[]	[]	0	hSpCas9	negative selection	2769822
72826762	72826785	11	-	27260157	MKN45	viability	CGCGGCTCCCAGTCACTGCCTGG	ATG16L2	ENSG00000168010	-0.570392432590494	[]	[]	-6	hSpCas9	negative selection	2771383
72826807	72826830	11	-	27260157	MKN45	viability	GCTCACAATAGGCACGGCCGAGG	ATG16L2	ENSG00000168010	0.0261722300652785	[]	[]	0	hSpCas9	negative selection	2793332
72826777	72826800	11	+	27260157	MKN45	viability	GAGCCGCGACCGGACAGTGAAGG	ATG16L2	ENSG00000168010	-0.17625993919706	[]	[]	0	hSpCas9	negative selection	2796069
72822268	72822291	11	+	27260157	MKN45	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-1.70866400445906	[]	[]	-9	hSpCas9	negative selection	2797115
72817780	72817803	11	-	27260157	MKN45	viability	GTGCGACCAGTGATGGGACTTGG	ATG16L2	ENSG00000168010	0.0620773228567024	[]	[]	0	hSpCas9	negative selection	2797538
72824811	72824834	11	-	27260157	MKN45	viability	CTGAGCCCGGGTAGGAAGTCGGG	ATG16L2	ENSG00000168010	0.0402208423887609	[]	[]	0	hSpCas9	negative selection	2799344
72824805	72824828	11	+	27260157	MKN45	viability	TGGCTGCCCGACTTCCTACCCGG	ATG16L2	ENSG00000168010	-0.148993523518334	[]	[]	0	hSpCas9	negative selection	2801505
72822262	72822285	11	-	27260157	RKO	viability	CTCGTTGCGCAGGTTGCGCTCGG	ATG16L2	ENSG00000168010	0.110006947270817	[]	[]	0	hSpCas9	negative selection	2802081
72826737	72826760	11	+	27260157	RKO	viability	CTGCCAAATTCAAGCTAACGAGG	ATG16L2	ENSG00000168010	0.986137731186288	[]	[]	9	hSpCas9	negative selection	2804169
72825317	72825340	11	+	27260157	RKO	viability	GAGGTCAATGCTGTTCGTTTTGG	ATG16L2	ENSG00000168010	0.314784263254317	[]	[]	1	hSpCas9	negative selection	2806106
72825298	72825321	11	+	27260157	RKO	viability	ACAGGATGCCCACCTCTCTGAGG	ATG16L2	ENSG00000168010	-0.127686673471083	[]	[]	0	hSpCas9	negative selection	2809503
72814544	72814567	11	-	27260157	RKO	viability	CACAGGCCGGCACCAGCTCCAGG	ATG16L2	ENSG00000168010	0.175096481279963	[]	[]	0	hSpCas9	negative selection	2814092
72826780	72826803	11	-	27260157	RKO	viability	ACTCCTTCACTGTCCGGTCGCGG	ATG16L2	ENSG00000168010	-0.0893273384629718	[]	[]	0	hSpCas9	negative selection	2814648
72824769	72824792	11	-	27260157	RKO	viability	GATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.764023248060211	[]	[]	8	hSpCas9	negative selection	2833043
72814471	72814494	11	-	27260157	RKO	viability	GCGTTTCCAGCGCGCTGCGGGGG	ATG16L2	ENSG00000168010	-0.885906133361874	[]	[]	-8	hSpCas9	negative selection	2842783
72822849	72822872	11	+	27260157	RKO	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.567294534834449	[]	[]	-7	hSpCas9	negative selection	2844771
72826767	72826790	11	+	27260157	RKO	viability	CAGTGACTGGGAGCCGCGACCGG	ATG16L2	ENSG00000168010	0.75040551091401	[]	[]	8	hSpCas9	negative selection	2845074
72822221	72822244	11	-	27260157	RKO	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.119282019608376	[]	[]	0	hSpCas9	negative selection	2845952
72826762	72826785	11	-	27260157	RKO	viability	CGCGGCTCCCAGTCACTGCCTGG	ATG16L2	ENSG00000168010	0.506710953859812	[]	[]	2	hSpCas9	negative selection	2847513
72826807	72826830	11	-	27260157	RKO	viability	GCTCACAATAGGCACGGCCGAGG	ATG16L2	ENSG00000168010	0.486551151256216	[]	[]	2	hSpCas9	negative selection	2869462
72826777	72826800	11	+	27260157	RKO	viability	GAGCCGCGACCGGACAGTGAAGG	ATG16L2	ENSG00000168010	1.15750957940786	[]	[]	9	hSpCas9	negative selection	2872199
72822268	72822291	11	+	27260157	RKO	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.870250942036414	[]	[]	-8	hSpCas9	negative selection	2873245
72817780	72817803	11	-	27260157	RKO	viability	GTGCGACCAGTGATGGGACTTGG	ATG16L2	ENSG00000168010	0.0898678069430535	[]	[]	0	hSpCas9	negative selection	2873668
72824811	72824834	11	-	27260157	RKO	viability	CTGAGCCCGGGTAGGAAGTCGGG	ATG16L2	ENSG00000168010	-0.22828575382884	[]	[]	-1	hSpCas9	negative selection	2875474
72824805	72824828	11	+	27260157	RKO	viability	TGGCTGCCCGACTTCCTACCCGG	ATG16L2	ENSG00000168010	0.309428120252687	[]	[]	1	hSpCas9	negative selection	2877635
72822262	72822285	11	-	27260157	SF268	viability	CTCGTTGCGCAGGTTGCGCTCGG	ATG16L2	ENSG00000168010	-0.324412185487878	[]	[]	-3	hSpCas9	negative selection	2878211
72826737	72826760	11	+	27260157	SF268	viability	CTGCCAAATTCAAGCTAACGAGG	ATG16L2	ENSG00000168010	0.786944881035213	[]	[]	8	hSpCas9	negative selection	2880299
72825317	72825340	11	+	27260157	SF268	viability	GAGGTCAATGCTGTTCGTTTTGG	ATG16L2	ENSG00000168010	-1.54853268560531	[]	[]	-8	hSpCas9	negative selection	2882236
72825298	72825321	11	+	27260157	SF268	viability	ACAGGATGCCCACCTCTCTGAGG	ATG16L2	ENSG00000168010	0.564056260078439	[]	[]	8	hSpCas9	negative selection	2885633
72814544	72814567	11	-	27260157	SF268	viability	CACAGGCCGGCACCAGCTCCAGG	ATG16L2	ENSG00000168010	0.365639360040158	[]	[]	4	hSpCas9	negative selection	2890222
72826780	72826803	11	-	27260157	SF268	viability	ACTCCTTCACTGTCCGGTCGCGG	ATG16L2	ENSG00000168010	-1.01210356869499	[]	[]	-7	hSpCas9	negative selection	2890778
72824769	72824792	11	-	27260157	SF268	viability	GATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.567415128106524	[]	[]	8	hSpCas9	negative selection	2909173
72814471	72814494	11	-	27260157	SF268	viability	GCGTTTCCAGCGCGCTGCGGGGG	ATG16L2	ENSG00000168010	-0.981682257246029	[]	[]	-7	hSpCas9	negative selection	2918913
72822849	72822872	11	+	27260157	SF268	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.0728285500885379	[]	[]	0	hSpCas9	negative selection	2920901
72826767	72826790	11	+	27260157	SF268	viability	CAGTGACTGGGAGCCGCGACCGG	ATG16L2	ENSG00000168010	0.336062382799024	[]	[]	4	hSpCas9	negative selection	2921204
72822221	72822244	11	-	27260157	SF268	viability	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.181134261968274	[]	[]	0	hSpCas9	negative selection	2922082
72826762	72826785	11	-	27260157	SF268	viability	CGCGGCTCCCAGTCACTGCCTGG	ATG16L2	ENSG00000168010	0.565758584516454	[]	[]	8	hSpCas9	negative selection	2923643
72826807	72826830	11	-	27260157	SF268	viability	GCTCACAATAGGCACGGCCGAGG	ATG16L2	ENSG00000168010	-0.488554426717097	[]	[]	-4	hSpCas9	negative selection	2945592
72826777	72826800	11	+	27260157	SF268	viability	GAGCCGCGACCGGACAGTGAAGG	ATG16L2	ENSG00000168010	0.329986859033378	[]	[]	4	hSpCas9	negative selection	2948329
72822268	72822291	11	+	27260157	SF268	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.221688255297903	[]	[]	-2	hSpCas9	negative selection	2949375
72817780	72817803	11	-	27260157	SF268	viability	GTGCGACCAGTGATGGGACTTGG	ATG16L2	ENSG00000168010	0.608714800582557	[]	[]	8	hSpCas9	negative selection	2949798
72824811	72824834	11	-	27260157	SF268	viability	CTGAGCCCGGGTAGGAAGTCGGG	ATG16L2	ENSG00000168010	0.0404008432165662	[]	[]	0	hSpCas9	negative selection	2951604
72824805	72824828	11	+	27260157	SF268	viability	TGGCTGCCCGACTTCCTACCCGG	ATG16L2	ENSG00000168010	-0.165085535093526	[]	[]	-1	hSpCas9	negative selection	2953765
72822505	72822528	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	0.4226411660656202	[3,3]	[3,5]	8	hSpCas9	positive selection	2972181
72821677	72821700	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	-1.5009427358664365	[2,2]	[0,0]	-9	hSpCas9	positive selection	2972182
72822240	72822263	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	0.0489265950660005	[2,1]	[2,0]	1	hSpCas9	positive selection	2972183
72816732	72816755	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	-0.10031263204465768	[1,2]	[2,0]	-1	hSpCas9	positive selection	2972184
72822505	72822528	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	0.10852303972958678	[3,3]	[5,1]	2	hSpCas9	positive selection	3040039
72821677	72821700	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	-0.40516649205289534	[2,2]	[2,0]	-6	hSpCas9	positive selection	3040040
72822240	72822263	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	0.209190123790993	[2,2]	[2,0]	4	hSpCas9	positive selection	3040041
72816732	72816755	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	0.7019092332178324	[1,1]	[3,1]	9	hSpCas9	positive selection	3040042
72828755	72828778		+	24336571	A375	resistance to PLX after 7 days	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.024258972712739857	[15,15]	[16,15]	0	hSpCas9	positive selection	3135256
72816726	72816749		+	24336571	A375	resistance to PLX after 7 days	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.20256815758522007	[3,3]	[4,3]	6	hSpCas9	positive selection	3135267
72816798	72816821		+	24336571	A375	resistance to PLX after 7 days	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	-0.187034965291764	[43,43]	[38,36]	-6	hSpCas9	positive selection	3135278
72828755	72828778		+	24336571	A375	resistance to PLX after 14 days	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.7119296117176879	[23,12]	[10,16]	6	hSpCas9	positive selection	3193049
72816726	72816749		+	24336571	A375	resistance to PLX after 14 days	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	1.483140049656095	[1,2]	[3,3]	9	hSpCas9	positive selection	3193060
72816798	72816821		+	24336571	A375	resistance to PLX after 14 days	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	-0.6835881141496608	[32,40]	[10,9]	-7	hSpCas9	positive selection	3193071
72828755	72828778		+	24336571	A375	viability after 7 days	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.24409691547739087	[13]	[15,15]	4	hSpCas9	negative selection	3250842
72816726	72816749		+	24336571	A375	viability after 7 days	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-1.1235190651403442	[9]	[3,3]	-9	hSpCas9	negative selection	3250853
72816798	72816821		+	24336571	A375	viability after 7 days	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	0.06722979237459747	[43]	[43,43]	1	hSpCas9	negative selection	3250864
72828755	72828778		+	24336571	A375	viability after 14 days	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.43280942495394353	[13]	[23,12]	5	hSpCas9	negative selection	3308635
72816726	72816749		+	24336571	A375	viability after 14 days	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-1.5073508207137638	[9]	[1,2]	-9	hSpCas9	negative selection	3308646
72816798	72816821		+	24336571	A375	viability after 14 days	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	-0.14680853486955936	[43]	[32,40]	-2	hSpCas9	negative selection	3308657
72821700	72821723	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	-0.2701763482618341	[184,183]	[0,0]	-2	hSpCas9	positive selection	3337933
72828761	72828784	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.5648873433793762	[91,114]	[0,0]	3	hSpCas9	positive selection	3337934
72817787	72817810	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.15150994866469228	[159,179]	[0,0]	-1	hSpCas9	positive selection	3337935
72821658	72821681	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3357186
72817798	72817821	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-6.163124681677816e-05	[152,152]	[0,0]	0	hSpCas9	positive selection	3357187
72828727	72828750	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	1.1280431945008687	[279,279]	[3,3]	5	hSpCas9	positive selection	3357188
72822504	72822527	11	+	26780180	HT29	viability (Avana library 4 designs)	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	0.570611367400192	[]	[]	2	hSpCas9	negative selection	3408320
72821676	72821699	11	+	26780180	HT29	viability (Avana library 4 designs)	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	4.81236521824651	[]	[]	9	hSpCas9	negative selection	3408321
72822239	72822262	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	0.123871979996877	[]	[]	0	hSpCas9	negative selection	3408322
72816732	72816755	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	1.00414661805141	[]	[]	4	hSpCas9	negative selection	3408323
72822504	72822527	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	3.01500800993474	[]	[]	4	hSpCas9	negative selection	3481801
72821676	72821699	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	-1.52823041129567	[]	[]	-2	hSpCas9	negative selection	3481802
72822239	72822262	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	4.99590884535076	[]	[]	8	hSpCas9	negative selection	3481803
72816732	72816755	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	-3.35191220488583	[]	[]	-4	hSpCas9	negative selection	3481804
72817837	72817860	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTCACCACAGACCAGCCGG	ATG16L2	ENSG00000168010	-2.06272083019899	[]	[]	-3	hSpCas9	negative selection	3481805
72814483	72814506	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	2.81844939729013	[]	[]	4	hSpCas9	negative selection	3481806
72822504	72822527	11	+	26780180	A375	viability (Avana lentiGuide)	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	-2.32331671866349	[]	[]	-4	hSpCas9	negative selection	3590460
72821676	72821699	11	+	26780180	A375	viability (Avana lentiGuide)	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	20.3409525022839	[]	[]	8	hSpCas9	negative selection	3590461
72822239	72822262	11	+	26780180	A375	viability (Avana lentiGuide)	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	6.3300696858263	[]	[]	5	hSpCas9	negative selection	3590462
72816732	72816755	11	-	26780180	A375	viability (Avana lentiGuide)	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	8.65461615759213	[]	[]	6	hSpCas9	negative selection	3590463
72817837	72817860	11	-	26780180	A375	viability (Avana lentiGuide)	TTACCTCACCACAGACCAGCCGG	ATG16L2	ENSG00000168010	4.87327889173685	[]	[]	4	hSpCas9	negative selection	3590464
72814483	72814506	11	+	26780180	A375	viability (Avana lentiGuide)	GCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	4.63270339715236	[]	[]	4	hSpCas9	negative selection	3590465
72822504	72822527	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	0.07578310738505942	[4]	[4,4]	2	hSpCas9	positive selection	3699119
72821676	72821699	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	-0.41936106213219865	[4]	[3,2]	-6	hSpCas9	positive selection	3699120
72822239	72822262	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	0.42028682074985585	[3]	[5,3]	9	hSpCas9	positive selection	3699121
72816732	72816755	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	-0.0752900262015336	[4]	[4,3]	-1	hSpCas9	positive selection	3699122
72817837	72817860	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTCACCACAGACCAGCCGG	ATG16L2	ENSG00000168010	-0.1099899551766747	[4]	[5,2]	-2	hSpCas9	positive selection	3699123
72814483	72814506	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.1564255412421405	[5]	[6,5]	4	hSpCas9	positive selection	3699124
72822504	72822527	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGAAGAAGGCTGCCAAGCGG	ATG16L2	ENSG00000168010	0.11735619645799757	[5]	[4,4]	2	hSpCas9	positive selection	3807726
72821676	72821699	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGTGGTGGAGAAGGGCGCGG	ATG16L2	ENSG00000168010	-1.7037819492858706	[5]	[1,0]	-9	hSpCas9	positive selection	3807727
72822239	72822262	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCGCAAGGCGCGCGCCGCGG	ATG16L2	ENSG00000168010	0.004924608650430207	[4]	[4,2]	0	hSpCas9	positive selection	3807728
72816732	72816755	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAGCCTTCTCTAAGAGATGG	ATG16L2	ENSG00000168010	-0.2807099727672222	[3]	[3,1]	-4	hSpCas9	positive selection	3807729
72817837	72817860	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTCACCACAGACCAGCCGG	ATG16L2	ENSG00000168010	-0.2529645627817997	[5]	[5,1]	-3	hSpCas9	positive selection	3807730
72814483	72814506	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	-0.004358154668320957	[6]	[5,4]	0	hSpCas9	positive selection	3807731
72817787	72817810	11	-	26780180	A375	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	1.07176874456446	[]	[]	5	hSpCas9	negative selection	3915975
72828727	72828750	11	+	26780180	A375	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.948133725361717	[]	[]	4	hSpCas9	negative selection	3915976
72821658	72821681	11	+	26780180	A375	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	1.07284254597877	[]	[]	5	hSpCas9	negative selection	3915977
72817798	72817821	11	+	26780180	A375	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	1.64326847364101	[]	[]	8	hSpCas9	negative selection	3915978
72828761	72828784	11	-	26780180	A375	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	1.75042538672099	[]	[]	9	hSpCas9	negative selection	3915979
72821700	72821723	11	-	26780180	A375	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.983771069999129	[]	[]	4	hSpCas9	negative selection	3915980
72817787	72817810	11	-	26780180	HT29	viability (GeCKOv2 library)	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	1.147968827158	[]	[]	5	hSpCas9	negative selection	4023941
72828727	72828750	11	+	26780180	HT29	viability (GeCKOv2 library)	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.0616633824423894	[]	[]	0	hSpCas9	negative selection	4023942
72821658	72821681	11	+	26780180	HT29	viability (GeCKOv2 library)	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	1.30378614009148	[]	[]	6	hSpCas9	negative selection	4023943
72817798	72817821	11	+	26780180	HT29	viability (GeCKOv2 library)	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	1.34398047378198	[]	[]	6	hSpCas9	negative selection	4023944
72828761	72828784	11	-	26780180	HT29	viability (GeCKOv2 library)	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.823999971722059	[]	[]	3	hSpCas9	negative selection	4023945
72821700	72821723	11	-	26780180	HT29	viability (GeCKOv2 library)	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.68964652374983	[]	[]	2	hSpCas9	negative selection	4023946
72828755	72828778	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.8579780876283438	[4]	[7,3]	9	hSpCas9	positive selection	4160177
72816726	72816749	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.16285057054693908	[1]	[0,1]	4	hSpCas9	positive selection	4160188
72816798	72816821	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	-0.06068058376371066	[5]	[3,3]	-1	hSpCas9	positive selection	4160200
72828755	72828778	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGGACCAAAGCTGTGTTCAGG	ATG16L2	ENSG00000168010	0.5756549883408606	[2]	[0,2,3,0]	4	hSpCas9	positive selection	4224199
72816726	72816749	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.09471446959097496	[1]	[0,0,1,0]	0	hSpCas9	positive selection	4224210
72816798	72816821	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCACTCCCACCACCCACCAGG	ATG16L2	ENSG00000168010	0.8337194415533882	[5]	[4,4,4,3]	5	hSpCas9	positive selection	4224222
72821700	72821723	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	-0.2957547870000661	[3]	[2,1]	-6	hSpCas9	positive selection	4257177
72828761	72828784	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.020591188862829277	[2]	[1,2]	0	hSpCas9	positive selection	4257178
72817787	72817810	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.5903501964126529	[3]	[1,0]	-8	hSpCas9	positive selection	4257179
72821658	72821681	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	-0.2895714794059795	[1]	[1,0]	-5	hSpCas9	positive selection	4321461
72817798	72817821	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.4804720164372813	[2]	[2,0]	-8	hSpCas9	positive selection	4321462
72828727	72828750	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.24324251597770308	[3]	[3,2]	5	hSpCas9	positive selection	4321463
72816727	72816749	11	+	27760321	OCIAML3	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-2.884425368190379	[31,27]	[0,5]	-9	hSpCas9	negative selection	4380264
72817787	72817809	11	-	27760321	OCIAML3	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.2458161922514197	[401,337]	[200,297]	-3	hSpCas9	negative selection	4380265
72822270	72822292	11	+	27760321	OCIAML3	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	0.24509572950932557	[630,569]	[490,640]	3	hSpCas9	negative selection	4380266
72822850	72822872	11	+	27760321	OCIAML3	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.26206378606236	[1101,764]	[709,1067]	3	hSpCas9	negative selection	4380267
72824769	72824791	11	-	27760321	OCIAML3	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.34258240211164925	[833,709]	[499,1105]	4	hSpCas9	negative selection	4380268
72816727	72816749	11	+	27760321	OCIAML2	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-0.1357251479298247	[31,27]	[15,29]	-2	hSpCas9	negative selection	4463727
72817787	72817809	11	-	27760321	OCIAML2	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.18426407739686312	[401,337]	[305,381]	2	hSpCas9	negative selection	4463728
72822270	72822292	11	+	27760321	OCIAML2	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	0.4026459903859452	[630,569]	[553,756]	5	hSpCas9	negative selection	4463729
72822850	72822872	11	+	27760321	OCIAML2	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.0892117734936958	[1101,764]	[620,807]	-1	hSpCas9	negative selection	4463730
72824769	72824791	11	-	27760321	OCIAML2	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.5410435946304619	[833,709]	[701,1173]	7	hSpCas9	negative selection	4463731
72816727	72816749	11	+	27760321	MV411	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	3.2092802053327443	[31,27]	[302,1]	9	hSpCas9	negative selection	4547190
72817787	72817809	11	-	27760321	MV411	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.18051220009270702	[401,337]	[244,168]	-1	hSpCas9	negative selection	4547191
72822270	72822292	11	+	27760321	MV411	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	0.6407060915182469	[630,569]	[466,842]	5	hSpCas9	negative selection	4547192
72822850	72822872	11	+	27760321	MV411	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.4844739786432939	[1101,764]	[749,1004]	3	hSpCas9	negative selection	4547193
72824769	72824791	11	-	27760321	MV411	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.891733089875427	[833,709]	[816,1129]	6	hSpCas9	negative selection	4547194
72816727	72816749	11	+	27760321	HL60	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.11292056442252285	[31,27]	[7,45]	1	hSpCas9	negative selection	4630653
72817787	72817809	11	-	27760321	HL60	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.056597050823396694	[401,337]	[267,360]	0	hSpCas9	negative selection	4630654
72822270	72822292	11	+	27760321	HL60	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.35168887255736136	[630,569]	[369,398]	-4	hSpCas9	negative selection	4630655
72822850	72822872	11	+	27760321	HL60	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.21072577654911062	[1101,764]	[628,674]	-2	hSpCas9	negative selection	4630656
72824769	72824791	11	-	27760321	HL60	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.21275595049524787	[833,709]	[675,783]	2	hSpCas9	negative selection	4630657
72816727	72816749	11	+	27760321	HT1080	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-3.3166380037395125	[27,21]	[0,0]	-7	hSpCas9	negative selection	4714116
72817787	72817809	11	-	27760321	HT1080	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.23532003188207545	[337,263]	[77,127]	-1	hSpCas9	negative selection	4714117
72822270	72822292	11	+	27760321	HT1080	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	1.3599421683207567	[569,444]	[485,554]	7	hSpCas9	negative selection	4714118
72822850	72822872	11	+	27760321	HT1080	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.18526981175251478	[764,596]	[391,216]	0	hSpCas9	negative selection	4714119
72824769	72824791	11	-	27760321	HT1080	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	1.4671811596191089	[709,553]	[718,670]	7	hSpCas9	negative selection	4714120
72816727	72816749	11	+	27760321	HT29	viability after 7 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.4889285816926705	[27,21]	[17,53,58]	7	hSpCas9	negative selection	4797579
72817787	72817809	11	-	27760321	HT29	viability after 7 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.6973539391557935	[337,263]	[1036,397,508]	9	hSpCas9	negative selection	4797580
72822270	72822292	11	+	27760321	HT29	viability after 7 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.05806211194244976	[569,444]	[489,618,746]	-1	hSpCas9	negative selection	4797581
72822850	72822872	11	+	27760321	HT29	viability after 7 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.8195481211492862	[764,596]	[1453,1605,1559]	9	hSpCas9	negative selection	4797582
72824769	72824791	11	-	27760321	HT29	viability after 7 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.3062388969318317	[709,553]	[1432,961,688]	5	hSpCas9	negative selection	4797583
72816727	72816749	11	+	27760321	HT29	viability after 25 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-1.8699190810660018	[27,21]	[0,13,8]	-8	hSpCas9	negative selection	4881042
72817787	72817809	11	-	27760321	HT29	viability after 25 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.7622793157667906	[337,263]	[474,580,713]	8	hSpCas9	negative selection	4881043
72822270	72822292	11	+	27760321	HT29	viability after 25 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.5555594523589004	[569,444]	[331,315,555]	-5	hSpCas9	negative selection	4881044
72822850	72822872	11	+	27760321	HT29	viability after 25 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.4354923905515332	[764,596]	[892,1150,1129]	5	hSpCas9	negative selection	4881045
72824769	72824791	11	-	27760321	HT29	viability after 25 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.34927970978579337	[709,553]	[883,768,1129]	4	hSpCas9	negative selection	4881046
72816727	72816749	11	+	27760321	HT29	viability after 22 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-2.0493317047610913	[27,21]	[4,9,5]	-8	hSpCas9	negative selection	4964505
72817787	72817809	11	-	27760321	HT29	viability after 22 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.591517343832034	[337,263]	[309,623,645]	6	hSpCas9	negative selection	4964506
72822270	72822292	11	+	27760321	HT29	viability after 22 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.15617445126274793	[569,444]	[448,564,567]	-1	hSpCas9	negative selection	4964507
72822850	72822872	11	+	27760321	HT29	viability after 22 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.41353691280081983	[764,596]	[706,1187,1261]	4	hSpCas9	negative selection	4964508
72824769	72824791	11	-	27760321	HT29	viability after 22 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.4411689994480068	[709,553]	[1003,822,1149]	5	hSpCas9	negative selection	4964509
72816727	72816749	11	+	27760321	HT29	viability after 19 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-0.15849189692949972	[27,21]	[55,23,0]	-1	hSpCas9	negative selection	5047968
72817787	72817809	11	-	27760321	HT29	viability after 19 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.43263853114988343	[337,263]	[366,352,655]	4	hSpCas9	negative selection	5047969
72822270	72822292	11	+	27760321	HT29	viability after 19 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.2606576021771386	[569,444]	[472,817,172]	-3	hSpCas9	negative selection	5047970
72822850	72822872	11	+	27760321	HT29	viability after 19 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.6728667866390975	[764,596]	[1175,1292,1247]	6	hSpCas9	negative selection	5047971
72824769	72824791	11	-	27760321	HT29	viability after 19 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.2034847147307628	[709,553]	[991,822,702]	2	hSpCas9	negative selection	5047972
72816727	72816749	11	+	27760321	HT29	viability after 16 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-2.7128582971055253	[27,21]	[5,2,3]	-9	hSpCas9	negative selection	5131431
72817787	72817809	11	-	27760321	HT29	viability after 16 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.3586844360498125	[337,263]	[379,413,496]	4	hSpCas9	negative selection	5131432
72822270	72822292	11	+	27760321	HT29	viability after 16 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.3794162221721064	[569,444]	[605,414,304]	-4	hSpCas9	negative selection	5131433
72822850	72822872	11	+	27760321	HT29	viability after 16 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.5503400447195302	[764,596]	[948,974,1410]	6	hSpCas9	negative selection	5131434
72824769	72824791	11	-	27760321	HT29	viability after 16 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.5276068495874944	[709,553]	[1292,655,1143]	6	hSpCas9	negative selection	5131435
72816727	72816749	11	+	27760321	HT29	viability after 13 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	0.4062714030853041	[27,21]	[65,5,42]	5	hSpCas9	negative selection	5214894
72817787	72817809	11	-	27760321	HT29	viability after 13 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.4889113464194578	[337,263]	[707,243,515]	6	hSpCas9	negative selection	5214895
72822270	72822292	11	+	27760321	HT29	viability after 13 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	-0.16217980833592094	[569,444]	[561,518,498]	-2	hSpCas9	negative selection	5214896
72822850	72822872	11	+	27760321	HT29	viability after 13 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.9647168557820375	[764,596]	[1568,1713,1353]	9	hSpCas9	negative selection	5214897
72824769	72824791	11	-	27760321	HT29	viability after 13 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.4169028360127731	[709,553]	[868,1078,987]	5	hSpCas9	negative selection	5214898
72816727	72816749	11	+	27760321	HT29	viability after 10 days	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	-0.6397649711307944	[27,21]	[36,9,12]	-6	hSpCas9	negative selection	5298357
72817787	72817809	11	-	27760321	HT29	viability after 10 days	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.33596265736053715	[337,263]	[436,649,343]	4	hSpCas9	negative selection	5298358
72822270	72822292	11	+	27760321	HT29	viability after 10 days	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	0.21087469251049495	[569,444]	[633,676,883]	2	hSpCas9	negative selection	5298359
72822850	72822872	11	+	27760321	HT29	viability after 10 days	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.6454689470265774	[764,596]	[1324,1555,1119]	8	hSpCas9	negative selection	5298360
72824769	72824791	11	-	27760321	HT29	viability after 10 days	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	0.19888090593330565	[709,553]	[773,864,1072]	2	hSpCas9	negative selection	5298361
72816727	72816749	11	+	27760321	MOLM13	viability	GATAACCATCTCTTAGAGAAGG	ATG16L2	ENSG00000168010	2.594572847668508	[31,27]	[0,187]	9	hSpCas9	negative selection	5381820
72817787	72817809	11	-	27760321	MOLM13	viability	CCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.9061737601749452	[401,337]	[379,397]	6	hSpCas9	negative selection	5381821
72822270	72822292	11	+	27760321	MOLM13	viability	AACCTGCGCAACGAGCGCCGGG	ATG16L2	ENSG00000168010	0.3183870219444602	[630,569]	[467,382]	2	hSpCas9	negative selection	5381822
72822850	72822872	11	+	27760321	MOLM13	viability	GCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	1.044820892788737	[1101,764]	[541,1526]	7	hSpCas9	negative selection	5381823
72824769	72824791	11	-	27760321	MOLM13	viability	ATCTGGTATCGCTGCTCAGGGG	ATG16L2	ENSG00000168010	1.5778579394526933	[833,709]	[1114,1449]	9	hSpCas9	negative selection	5381824
72814411	72814434	11	+	27661255	K562	viability	GGGAGGAACGCGCCGCTAGGCGG	ATG16L2	ENSG00000168010	0.06858448884478863	[1102,1002]	[949,826]	2	dCas9-KRAB	negative selection	5464001
72814483	72814506	11	+	27661255	K562	viability	GCTGGAAACGCCACATCGTGCGG	ATG16L2	ENSG00000168010	0.14822757000355535	[197,177]	[176,157]	5	dCas9-KRAB	negative selection	5464002
72814423	72814446	11	-	27661255	K562	viability	GGCCGCGCTCTCCCGCCTAGCGG	ATG16L2	ENSG00000168010	0.27993588634018807	[403,554]	[483,443]	8	dCas9-KRAB	negative selection	5464003
72821700	72821723	11	-	27260156	BXPC3	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.15829011046365993	[570]	[536,622,733,800]	3	hSpCas9	negative selection	5529637
72828761	72828784	11	-	27260156	BXPC3	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.09306936541379829	[359]	[275,379,348,418]	-2	hSpCas9	negative selection	5529638
72817787	72817810	11	-	27260156	BXPC3	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.03266681170490672	[490]	[441,421,682,573]	0	hSpCas9	negative selection	5529639
72821658	72821681	11	+	27260156	BXPC3	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.20783823000824553	[164]	[136,191,244,233]	4	hSpCas9	negative selection	5593921
72817798	72817821	11	+	27260156	BXPC3	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.16085558905143948	[347]	[302,302,357,341]	-4	hSpCas9	negative selection	5593922
72828727	72828750	11	+	27260156	BXPC3	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.16200366707688696	[572]	[672,679,661,658]	3	hSpCas9	negative selection	5593923
72821700	72821723	11	-	27260156	A673	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.28480592881734906	[570]	[933,834,681,904]	6	hSpCas9	negative selection	5650888
72828761	72828784	11	-	27260156	A673	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.012658394155143415	[359]	[453,452,406,399]	0	hSpCas9	negative selection	5650889
72817787	72817810	11	-	27260156	A673	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.3335372667163895	[490]	[617,921,634,778]	7	hSpCas9	negative selection	5650890
72821658	72821681	11	+	27260156	A673	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.3546895661344398	[164]	[266,269,285,186]	7	hSpCas9	negative selection	5715172
72817798	72817821	11	+	27260156	A673	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.22923027125790618	[347]	[485,235,308,415]	-5	hSpCas9	negative selection	5715173
72828727	72828750	11	+	27260156	A673	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.0757938963723403	[572]	[740,636,704,825]	1	hSpCas9	negative selection	5715174
72821700	72821723	11	-	27260156	A375	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.27064094129257127	[570]	[570,1308,714,700]	4	hSpCas9	negative selection	5772139
72828761	72828784	11	-	27260156	A375	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.17292865440088556	[359]	[311,560,277,365]	-2	hSpCas9	negative selection	5772140
72817787	72817810	11	-	27260156	A375	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.009656839761213704	[490]	[504,841,461,538]	0	hSpCas9	negative selection	5772141
72821658	72821681	11	+	27260156	A375	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.1946672288037088	[164]	[180,323,257,141]	3	hSpCas9	negative selection	5836423
72817798	72817821	11	+	27260156	A375	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.3663072748690923	[347]	[521,348,123,275]	-5	hSpCas9	negative selection	5836424
72828727	72828750	11	+	27260156	A375	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.006238182720203933	[572]	[539,648,752,711]	0	hSpCas9	negative selection	5836425
72821700	72821723	11	-	27260156	COLO741	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.4337612641872108	[570]	[1063,1040,864]	8	hSpCas9	negative selection	5893390
72828761	72828784	11	-	27260156	COLO741	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.27626417212307397	[359]	[388,309,435]	-5	hSpCas9	negative selection	5893391
72817787	72817810	11	-	27260156	COLO741	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.1627823566339148	[490]	[774,601,731]	3	hSpCas9	negative selection	5893392
72821658	72821681	11	+	27260156	COLO741	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.23230557587941703	[164]	[302,307,143]	5	hSpCas9	negative selection	5957674
72817798	72817821	11	+	27260156	COLO741	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.166501760842652	[347]	[322,300,545]	-4	hSpCas9	negative selection	5957675
72828727	72828750	11	+	27260156	COLO741	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.1022405199367285	[572]	[902,946,534]	2	hSpCas9	negative selection	5957676
72821700	72821723	11	-	27260156	CAL120	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.22666594445009053	[570]	[962,789,761]	3	hSpCas9	negative selection	6014641
72828761	72828784	11	-	27260156	CAL120	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.45504373507534224	[359]	[300,271,401]	-6	hSpCas9	negative selection	6014642
72817787	72817810	11	-	27260156	CAL120	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.3112378702504631	[490]	[435,394,634]	-4	hSpCas9	negative selection	6014643
72821658	72821681	11	+	27260156	CAL120	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.3271960699459362	[164]	[326,191,263]	5	hSpCas9	negative selection	6078925
72817798	72817821	11	+	27260156	CAL120	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	0.09581455398720923	[347]	[363,529,478]	1	hSpCas9	negative selection	6078926
72828727	72828750	11	+	27260156	CAL120	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.16852697314449883	[572]	[845,788,775]	2	hSpCas9	negative selection	6078927
72821700	72821723	11	-	27260156	CADOES1	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.1513055233870369	[570]	[578,727,474,576]	2	hSpCas9	negative selection	6135892
72828761	72828784	11	-	27260156	CADOES1	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.16813051065753348	[359]	[255,647,243,356]	3	hSpCas9	negative selection	6135893
72817787	72817810	11	-	27260156	CADOES1	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.023464196649994898	[490]	[583,464,401,402]	0	hSpCas9	negative selection	6135894
72821658	72821681	11	+	27260156	CADOES1	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.15335899147567145	[164]	[183,176,167,152]	2	hSpCas9	negative selection	6200176
72817798	72817821	11	+	27260156	CADOES1	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.42942252899447086	[347]	[235,195,218,312]	-6	hSpCas9	negative selection	6200177
72828727	72828750	11	+	27260156	CADOES1	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.09557999617342566	[572]	[491,428,597,474]	-2	hSpCas9	negative selection	6200178
72821700	72821723	11	-	27260156	EWS502	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.5764730257144084	[570]	[914,734,791,1185]	8	hSpCas9	negative selection	6257143
72828761	72828784	11	-	27260156	EWS502	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.04952312005156262	[359]	[275,360,437,412]	-1	hSpCas9	negative selection	6257144
72817787	72817810	11	-	27260156	EWS502	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.10096194487924426	[490]	[534,615,434,647]	1	hSpCas9	negative selection	6257145
72821658	72821681	11	+	27260156	EWS502	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	-0.031183913430178345	[164]	[79,181,186,250]	0	hSpCas9	negative selection	6321427
72817798	72817821	11	+	27260156	EWS502	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.00894987938982661	[347]	[191,508,280,505]	0	hSpCas9	negative selection	6321428
72828727	72828750	11	+	27260156	EWS502	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.12138035259689822	[572]	[353,836,775,705]	2	hSpCas9	negative selection	6321429
72821700	72821723	11	-	27260156	EW8	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.1460696654059363	[570]	[641,697,372,372]	2	hSpCas9	negative selection	6378394
72828761	72828784	11	-	27260156	EW8	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.020123875665891577	[359]	[426,212,245,318]	0	hSpCas9	negative selection	6378395
72817787	72817810	11	-	27260156	EW8	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.24455654941212407	[490]	[577,375,462,479]	4	hSpCas9	negative selection	6378396
72821658	72821681	11	+	27260156	EW8	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	1.282424349586328	[164]	[242,233,457,332]	9	hSpCas9	negative selection	6442678
72817798	72817821	11	+	27260156	EW8	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.13835072690952033	[347]	[304,203,215,310]	-3	hSpCas9	negative selection	6442679
72828727	72828750	11	+	27260156	EW8	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.07734129549217639	[572]	[589,538,369,490]	1	hSpCas9	negative selection	6442680
72821700	72821723	11	-	27260156	CORL105	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.26581700737987074	[570]	[736,872,791,806]	5	hSpCas9	negative selection	6499645
72828761	72828784	11	-	27260156	CORL105	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.47017328754335364	[359]	[361,350,270,228]	-7	hSpCas9	negative selection	6499646
72817787	72817810	11	-	27260156	CORL105	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.1080816679539801	[490]	[605,461,545,524]	-2	hSpCas9	negative selection	6499647
72821658	72821681	11	+	27260156	CORL105	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.35330253130668887	[164]	[190,187,210,389]	6	hSpCas9	negative selection	6563929
72817798	72817821	11	+	27260156	CORL105	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.4736620290794884	[347]	[295,309,272,290]	-7	hSpCas9	negative selection	6563930
72828727	72828750	11	+	27260156	CORL105	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.1606661683449185	[572]	[560,566,754,540]	-3	hSpCas9	negative selection	6563931
72821700	72821723	11	-	27260156	HS294T	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.3066144106423245	[570]	[222,350,233,287]	4	hSpCas9	negative selection	6620896
72828761	72828784	11	-	27260156	HS294T	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.5689175959511239	[359]	[295,92,226,203]	7	hSpCas9	negative selection	6620897
72817787	72817810	11	-	27260156	HS294T	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.8675767887813535	[490]	[215,260,456,489]	9	hSpCas9	negative selection	6620898
72821658	72821681	11	+	27260156	HS294T	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.4607794730615882	[164]	[90,57,57,155]	6	hSpCas9	negative selection	6685180
72817798	72817821	11	+	27260156	HS294T	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	0.15772236536706263	[347]	[96,141,82,309]	2	hSpCas9	negative selection	6685181
72828727	72828750	11	+	27260156	HS294T	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.23387831699210015	[572]	[158,224,219,485]	3	hSpCas9	negative selection	6685182
72821700	72821723	11	-	27260156	HCC44	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.19092606507158105	[570]	[902,486,810,802]	3	hSpCas9	negative selection	6742147
72828761	72828784	11	-	27260156	HCC44	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.33865909196187705	[359]	[626,143,296,267]	-5	hSpCas9	negative selection	6742148
72817787	72817810	11	-	27260156	HCC44	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.153505185438759	[490]	[635,557,761,546]	2	hSpCas9	negative selection	6742149
72821658	72821681	11	+	27260156	HCC44	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.1714496790139246	[164]	[305,112,190,246]	2	hSpCas9	negative selection	6806431
72817798	72817821	11	+	27260156	HCC44	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.12985160717706712	[347]	[403,254,407,394]	-2	hSpCas9	negative selection	6806432
72828727	72828750	11	+	27260156	HCC44	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.29501328922153114	[572]	[775,710,791,900]	5	hSpCas9	negative selection	6806433
72821700	72821723	11	-	27260156	G402	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.4150916175369446	[570]	[1036,657,954,1055]	5	hSpCas9	negative selection	6863398
72828761	72828784	11	-	27260156	G402	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.06988535389971073	[359]	[707,313,542,311]	0	hSpCas9	negative selection	6863399
72817787	72817810	11	-	27260156	G402	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.42975978804781567	[490]	[793,749,852,821]	5	hSpCas9	negative selection	6863400
72821658	72821681	11	+	27260156	G402	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	-0.01217050159179256	[164]	[123,66,257,323]	0	hSpCas9	negative selection	6927682
72817798	72817821	11	+	27260156	G402	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	0.07510056826279987	[347]	[336,475,273,674]	0	hSpCas9	negative selection	6927683
72828727	72828750	11	+	27260156	G402	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.366522788431171	[572]	[843,353,654,355]	-4	hSpCas9	negative selection	6927684
72821700	72821723	11	-	27260156	L33	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.17802778274587044	[570]	[582,258,422,696]	4	hSpCas9	negative selection	6984649
72828761	72828784	11	-	27260156	L33	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.03333414185649414	[359]	[385,106,241,373]	0	hSpCas9	negative selection	6984650
72817787	72817810	11	-	27260156	L33	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.4632844306446789	[490]	[688,282,471,577]	8	hSpCas9	negative selection	6984651
72821658	72821681	11	+	27260156	L33	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	-0.08658465752092193	[164]	[200,50,136,77]	-2	hSpCas9	negative selection	7048933
72817798	72817821	11	+	27260156	L33	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.49279715464337726	[347]	[223,109,171,223]	-8	hSpCas9	negative selection	7048934
72828727	72828750	11	+	27260156	L33	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.06585992207003583	[572]	[612,221,407,594]	1	hSpCas9	negative selection	7048935
72821700	72821723	11	-	27260156	K562	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.2201915580815907	[570]	[635,463,658,595]	2	hSpCas9	negative selection	7105900
72828761	72828784	11	-	27260156	K562	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.7505957813050077	[359]	[162,181,257,156]	-7	hSpCas9	negative selection	7105901
72817787	72817810	11	-	27260156	K562	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.48842453581807144	[490]	[253,221,258,476]	-5	hSpCas9	negative selection	7105902
72821658	72821681	11	+	27260156	K562	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.6696050602605621	[164]	[157,246,350,175]	8	hSpCas9	negative selection	7170184
72817798	72817821	11	+	27260156	K562	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.6001243190784783	[347]	[184,148,312,166]	-6	hSpCas9	negative selection	7170185
72828727	72828750	11	+	27260156	K562	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.40496734604328066	[572]	[460,519,352,231]	-5	hSpCas9	negative selection	7170186
72821700	72821723	11	-	27260156	HT29	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.24079823537579198	[570]	[926,1023,811,568]	5	hSpCas9	negative selection	7227151
72828761	72828784	11	-	27260156	HT29	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.06994868979000163	[359]	[365,651,406,422]	1	hSpCas9	negative selection	7227152
72817787	72817810	11	-	27260156	HT29	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.337118875684032	[490]	[683,1064,638,655]	6	hSpCas9	negative selection	7227153
72821658	72821681	11	+	27260156	HT29	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.12165585116935151	[164]	[272,186,240,176]	2	hSpCas9	negative selection	7291435
72817798	72817821	11	+	27260156	HT29	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.24579802371272597	[347]	[516,229,367,315]	-5	hSpCas9	negative selection	7291436
72828727	72828750	11	+	27260156	HT29	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.3082389513426663	[572]	[864,864,842,869]	6	hSpCas9	negative selection	7291437
72821700	72821723	11	-	27260156	MHHES1	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.02311587652344954	[570]	[759,804,622,479]	0	hSpCas9	negative selection	7348402
72828761	72828784	11	-	27260156	MHHES1	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.08644356493558014	[359]	[259,639,362,288]	-2	hSpCas9	negative selection	7348403
72817787	72817810	11	-	27260156	MHHES1	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.15950834339546524	[490]	[551,530,869,512]	3	hSpCas9	negative selection	7348404
72821658	72821681	11	+	27260156	MHHES1	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.4586969555439442	[164]	[283,263,217,253]	7	hSpCas9	negative selection	7412686
72817798	72817821	11	+	27260156	MHHES1	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.8277350075203754	[347]	[204,200,366,124]	-9	hSpCas9	negative selection	7412687
72828727	72828750	11	+	27260156	MHHES1	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.3073054159216789	[572]	[589,576,544,403]	-5	hSpCas9	negative selection	7412688
72821700	72821723	11	-	27260156	MEWO	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.2891895217577554	[570]	[752,569,654]	6	hSpCas9	negative selection	7469653
72828761	72828784	11	-	27260156	MEWO	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.23878999002292778	[359]	[259,343,246]	-5	hSpCas9	negative selection	7469654
72817787	72817810	11	-	27260156	MEWO	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.044167015494720255	[490]	[455,335,546]	-1	hSpCas9	negative selection	7469655
72821658	72821681	11	+	27260156	MEWO	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.27577052169857574	[164]	[149,281,120]	6	hSpCas9	negative selection	7533937
72817798	72817821	11	+	27260156	MEWO	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.4150077312720546	[347]	[241,260,228]	-7	hSpCas9	negative selection	7533938
72828727	72828750	11	+	27260156	MEWO	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.22377987084251705	[572]	[610,630,632]	5	hSpCas9	negative selection	7533939
72821700	72821723	11	-	27260156	LNCAPCLONEFGC	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.2090701709188698	[570]	[661,707,498,498]	3	hSpCas9	negative selection	7590904
72828761	72828784	11	-	27260156	LNCAPCLONEFGC	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.2012422852903688	[359]	[283,297,374,189]	-3	hSpCas9	negative selection	7590905
72817787	72817810	11	-	27260156	LNCAPCLONEFGC	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.3333317098283289	[490]	[552,444,688,580]	5	hSpCas9	negative selection	7590906
72821658	72821681	11	+	27260156	LNCAPCLONEFGC	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.2963296659827108	[164]	[205,146,189,193]	4	hSpCas9	negative selection	7655188
72817798	72817821	11	+	27260156	LNCAPCLONEFGC	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.26495648053566934	[347]	[196,106,391,383]	-4	hSpCas9	negative selection	7655189
72828727	72828750	11	+	27260156	LNCAPCLONEFGC	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.3376743634156122	[572]	[628,642,684,671]	5	hSpCas9	negative selection	7655190
72821700	72821723	11	-	27260156	PANC0327	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.4255417786827785	[570]	[731,613,858,532]	6	hSpCas9	negative selection	7712155
72828761	72828784	11	-	27260156	PANC0327	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.18514284586661156	[359]	[267,279,244,330]	-3	hSpCas9	negative selection	7712156
72817787	72817810	11	-	27260156	PANC0327	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.14453715459979374	[490]	[407,307,668,559]	2	hSpCas9	negative selection	7712157
72821658	72821681	11	+	27260156	PANC0327	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.8066824372386421	[164]	[404,268,214,146]	9	hSpCas9	negative selection	7776439
72817798	72817821	11	+	27260156	PANC0327	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.0051890919141873715	[347]	[242,327,283,368]	0	hSpCas9	negative selection	7776440
72828727	72828750	11	+	27260156	PANC0327	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.4530321426256123	[572]	[925,528,539,831]	6	hSpCas9	negative selection	7776441
72821700	72821723	11	-	27260156	NCIH2009	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.3477616624139574	[570]	[1016,1088,936]	5	hSpCas9	negative selection	7833406
72828761	72828784	11	-	27260156	NCIH2009	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.33943032187143074	[359]	[531,551,804]	4	hSpCas9	negative selection	7833407
72817787	72817810	11	-	27260156	NCIH2009	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.42517480648728617	[490]	[1026,795,961]	6	hSpCas9	negative selection	7833408
72821658	72821681	11	+	27260156	NCIH2009	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.503076636558623	[164]	[423,371,201]	7	hSpCas9	negative selection	7897690
72817798	72817821	11	+	27260156	NCIH2009	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.46621292277625714	[347]	[431,355,282]	-6	hSpCas9	negative selection	7897691
72828727	72828750	11	+	27260156	NCIH2009	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.019720573761068227	[572]	[860,709,873]	0	hSpCas9	negative selection	7897692
72821700	72821723	11	-	27260156	NCIH1373	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.14810558034912386	[570]	[963,707,584,160]	1	hSpCas9	negative selection	7954657
72828761	72828784	11	-	27260156	NCIH1373	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.6887223094170585	[359]	[349,200,215,66]	-6	hSpCas9	negative selection	7954658
72817787	72817810	11	-	27260156	NCIH1373	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.5248837492891628	[490]	[421,406,301,105]	-5	hSpCas9	negative selection	7954659
72821658	72821681	11	+	27260156	NCIH1373	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.24850553876831927	[164]	[311,144,71,100]	2	hSpCas9	negative selection	8018941
72817798	72817821	11	+	27260156	NCIH1373	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.33174315851123526	[347]	[195,70,414,151]	-3	hSpCas9	negative selection	8018942
72828727	72828750	11	+	27260156	NCIH1373	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.2577062037633365	[572]	[591,389,477,189]	-3	hSpCas9	negative selection	8018943
72821700	72821723	11	-	27260156	PATU8902	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.2645787085962554	[570]	[1227,842,732,1077]	2	hSpCas9	negative selection	8075908
72828761	72828784	11	-	27260156	PATU8902	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.5449584517481473	[359]	[662,326,230,152]	-5	hSpCas9	negative selection	8075909
72817787	72817810	11	-	27260156	PATU8902	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.19159784835351484	[490]	[872,785,562,973]	2	hSpCas9	negative selection	8075910
72821658	72821681	11	+	27260156	PATU8902	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.332322361707144	[164]	[283,335,115,487]	3	hSpCas9	negative selection	8140192
72817798	72817821	11	+	27260156	PATU8902	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	0.3421838858085503	[347]	[284,1279,297,686]	3	hSpCas9	negative selection	8140193
72828727	72828750	11	+	27260156	PATU8902	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.1240085087509196	[572]	[588,1103,462,854]	-1	hSpCas9	negative selection	8140194
72821700	72821723	11	-	27260156	PANC1	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.265394941082481	[570]	[534,822,507,538]	4	hSpCas9	negative selection	8197159
72828761	72828784	11	-	27260156	PANC1	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.06762679938838323	[359]	[346,351,387,225]	1	hSpCas9	negative selection	8197160
72817787	72817810	11	-	27260156	PANC1	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.5261831940923305	[490]	[578,926,677,345]	8	hSpCas9	negative selection	8197161
72821658	72821681	11	+	27260156	PANC1	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.4433642815554901	[164]	[188,168,390,40]	7	hSpCas9	negative selection	8261443
72817798	72817821	11	+	27260156	PANC1	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.19226913817675784	[347]	[164,355,368,186]	-3	hSpCas9	negative selection	8261444
72828727	72828750	11	+	27260156	PANC1	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.10676040833201772	[572]	[483,697,574,409]	1	hSpCas9	negative selection	8261445
72821700	72821723	11	-	27260156	PANC0813	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.32679136214950383	[570]	[740,946,822,842]	5	hSpCas9	negative selection	8318410
72828761	72828784	11	-	27260156	PANC0813	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.11507589677015173	[359]	[383,593,543,310]	2	hSpCas9	negative selection	8318411
72817787	72817810	11	-	27260156	PANC0813	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.2664577982232776	[490]	[839,584,697,665]	4	hSpCas9	negative selection	8318412
72821658	72821681	11	+	27260156	PANC0813	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.025817200723245337	[164]	[172,218,202,191]	0	hSpCas9	negative selection	8382694
72817798	72817821	11	+	27260156	PANC0813	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.08691160112081586	[347]	[424,313,353,445]	-1	hSpCas9	negative selection	8382695
72828727	72828750	11	+	27260156	PANC0813	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.4168164141962316	[572]	[928,957,946,768]	6	hSpCas9	negative selection	8382696
72821700	72821723	11	-	27260156	RDES	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.11287947626327022	[570]	[530,662,1033,635]	1	hSpCas9	negative selection	8439661
72828761	72828784	11	-	27260156	RDES	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.5333939262263574	[359]	[239,266,186,478]	-7	hSpCas9	negative selection	8439662
72817787	72817810	11	-	27260156	RDES	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.11961870807872552	[490]	[361,488,605,670]	-2	hSpCas9	negative selection	8439663
72821658	72821681	11	+	27260156	RDES	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.3190622462669297	[164]	[102,254,327,294]	5	hSpCas9	negative selection	8503945
72817798	72817821	11	+	27260156	RDES	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.4367625565420319	[347]	[314,278,262,313]	-6	hSpCas9	negative selection	8503946
72828727	72828750	11	+	27260156	RDES	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.22633794692748255	[572]	[480,537,669,571]	-4	hSpCas9	negative selection	8503947
72821700	72821723	11	-	27260156	PC3	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.515531822821536	[570]	[505,876,1644,592]	9	hSpCas9	negative selection	8560912
72828761	72828784	11	-	27260156	PC3	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.10421120451249749	[359]	[128,440,598,330]	-2	hSpCas9	negative selection	8560913
72817787	72817810	11	-	27260156	PC3	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.20402892659619953	[490]	[279,402,1113,771]	4	hSpCas9	negative selection	8560914
72821658	72821681	11	+	27260156	PC3	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.5236123056429521	[164]	[155,320,274,212]	9	hSpCas9	negative selection	8625196
72817798	72817821	11	+	27260156	PC3	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.3621409960444013	[347]	[331,182,238,240]	-7	hSpCas9	negative selection	8625197
72828727	72828750	11	+	27260156	PC3	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.0913568042409546	[572]	[370,545,931,767]	2	hSpCas9	negative selection	8625198
72821700	72821723	11	-	27260156	PATU8988T	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.4798867477323701	[570]	[796,620,742,914]	7	hSpCas9	negative selection	8682163
72828761	72828784	11	-	27260156	PATU8988T	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.15640376440375958	[359]	[305,468,216,268]	-3	hSpCas9	negative selection	8682164
72817787	72817810	11	-	27260156	PATU8988T	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.06876493643036748	[490]	[475,493,353,493]	-1	hSpCas9	negative selection	8682165
72821658	72821681	11	+	27260156	PATU8988T	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.956842802224119	[164]	[308,325,349,248]	9	hSpCas9	negative selection	8746447
72817798	72817821	11	+	27260156	PATU8988T	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.14391608874205497	[347]	[223,217,177,615]	-2	hSpCas9	negative selection	8746448
72828727	72828750	11	+	27260156	PATU8988T	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.10684008329748146	[572]	[313,706,443,618]	-2	hSpCas9	negative selection	8746449
72821700	72821723	11	-	27260156	T47D	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.26350332883380795	[570]	[690,821,857,819]	5	hSpCas9	negative selection	8803414
72828761	72828784	11	-	27260156	T47D	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.19356934762766476	[359]	[427,306,374,361]	-4	hSpCas9	negative selection	8803415
72817787	72817810	11	-	27260156	T47D	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	-0.15060979818847253	[490]	[587,414,500,567]	-3	hSpCas9	negative selection	8803416
72821658	72821681	11	+	27260156	T47D	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.2480978479134892	[164]	[253,148,270,245]	5	hSpCas9	negative selection	8867698
72817798	72817821	11	+	27260156	T47D	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.4310386348820002	[347]	[415,274,271,240]	-7	hSpCas9	negative selection	8867699
72828727	72828750	11	+	27260156	T47D	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.014858668005042708	[572]	[590,644,766,695]	0	hSpCas9	negative selection	8867700
72821700	72821723	11	-	27260156	SU8686	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.29189858646654804	[570]	[712,541,787,753]	5	hSpCas9	negative selection	8924665
72828761	72828784	11	-	27260156	SU8686	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.1850385415430229	[359]	[210,266,316,507]	-3	hSpCas9	negative selection	8924666
72817787	72817810	11	-	27260156	SU8686	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.5012666287544227	[490]	[780,437,765,809]	8	hSpCas9	negative selection	8924667
72821658	72821681	11	+	27260156	SU8686	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.15456225783129285	[164]	[229,129,194,171]	2	hSpCas9	negative selection	8988949
72817798	72817821	11	+	27260156	SU8686	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.3249691470772841	[347]	[321,206,211,376]	-5	hSpCas9	negative selection	8988950
72828727	72828750	11	+	27260156	SU8686	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.101333214433807	[572]	[548,490,737,694]	1	hSpCas9	negative selection	8988951
72821700	72821723	11	-	27260156	SKES1	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.1727938938876753	[570]	[539,662,714,631]	4	hSpCas9	negative selection	9045916
72828761	72828784	11	-	27260156	SKES1	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.21460222201490653	[359]	[274,461,279,239]	-5	hSpCas9	negative selection	9045917
72817787	72817810	11	-	27260156	SKES1	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.31247929446592665	[490]	[666,663,682,445]	6	hSpCas9	negative selection	9045918
72821658	72821681	11	+	27260156	SKES1	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.04141889486643113	[164]	[119,174,234,141]	0	hSpCas9	negative selection	9110200
72817798	72817821	11	+	27260156	SKES1	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.25110552900630234	[347]	[484,283,206,222]	-5	hSpCas9	negative selection	9110201
72828727	72828750	11	+	27260156	SKES1	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.05030358129422452	[572]	[657,601,556,558]	1	hSpCas9	negative selection	9110202
72821700	72821723	11	-	27260156	TOV112D	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.3935731310388592	[570]	[666,732,906,686]	7	hSpCas9	negative selection	9167167
72828761	72828784	11	-	27260156	TOV112D	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.49000773192374036	[359]	[261,319,185,273]	-7	hSpCas9	negative selection	9167168
72817787	72817810	11	-	27260156	TOV112D	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.21026226582793855	[490]	[406,676,500,698]	4	hSpCas9	negative selection	9167169
72821658	72821681	11	+	27260156	TOV112D	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.22213222463345295	[164]	[353,213,117,105]	4	hSpCas9	negative selection	9231451
72817798	72817821	11	+	27260156	TOV112D	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.2172997766207515	[347]	[497,342,119,265]	-4	hSpCas9	negative selection	9231452
72828727	72828750	11	+	27260156	TOV112D	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.22996818287551646	[572]	[656,897,475,712]	4	hSpCas9	negative selection	9231453
72821700	72821723	11	-	27260156	TC71	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.31163366022136835	[570]	[798,809,597,840]	7	hSpCas9	negative selection	9288418
72828761	72828784	11	-	27260156	TC71	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	-0.1977180979295683	[359]	[285,413,249,403]	-5	hSpCas9	negative selection	9288419
72817787	72817810	11	-	27260156	TC71	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.21041417802249135	[490]	[575,587,649,621]	5	hSpCas9	negative selection	9288420
72821658	72821681	11	+	27260156	TC71	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.19211489453755726	[164]	[183,200,240,179]	5	hSpCas9	negative selection	9352702
72817798	72817821	11	+	27260156	TC71	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.3482820239774196	[347]	[245,282,361,278]	-7	hSpCas9	negative selection	9352703
72828727	72828750	11	+	27260156	TC71	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	0.046751163019058684	[572]	[544,697,669,624]	1	hSpCas9	negative selection	9352704
72821700	72821723	11	-	27260156	TC32	viability	GCTCCGACTCCAGCGTGCCCAGG	ATG16L2	ENSG00000168010	0.3890959750786532	[570]	[640,551,948,735]	6	hSpCas9	negative selection	9409669
72828761	72828784	11	-	27260156	TC32	viability	GACATACCTGAACACAGCTTTGG	ATG16L2	ENSG00000168010	0.04424127519565457	[359]	[332,263,410,414]	0	hSpCas9	negative selection	9409670
72817787	72817810	11	-	27260156	TC32	viability	ACCCTCAGTGCGACCAGTGATGG	ATG16L2	ENSG00000168010	0.1686076109083038	[490]	[462,267,618,833]	3	hSpCas9	negative selection	9409671
72821658	72821681	11	+	27260156	TC32	viability	CCGCCCCCAGATGGCCTACCAGG	ATG16L2	ENSG00000168010	0.39170030008075174	[164]	[255,151,208,196]	6	hSpCas9	negative selection	9473953
72817798	72817821	11	+	27260156	TC32	viability	CGCACTGAGGGTGAAGTGGCAGG	ATG16L2	ENSG00000168010	-0.45915749043360043	[347]	[208,198,336,226]	-7	hSpCas9	negative selection	9473954
72828727	72828750	11	+	27260156	TC32	viability	AGGGCCGATGGCTTCAAGTGTGG	ATG16L2	ENSG00000168010	-0.2908455359709538	[572]	[419,268,599,547]	-5	hSpCas9	negative selection	9473955
72814514	72814537	11	+	27869803	HPAFII	viability after 27 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.6625026821239914	[1001]	[631,1001,NaN]	5	hSpCas9	negative selection	9543918
72816822	72816845	11	-	27869803	HPAFII	viability after 27 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.1923646979899267	[244]	[93,24,NaN]	-7	hSpCas9	negative selection	9543919
72817738	72817761	11	+	27869803	HPAFII	viability after 27 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.21230993130881604	[229]	[162,120,NaN]	1	hSpCas9	negative selection	9543920
72822221	72822244	11	-	27869803	HPAFII	viability after 27 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-1.1727700709567654	[91]	[45,0,NaN]	-7	hSpCas9	negative selection	9543921
72822466	72822489	11	+	27869803	HPAFII	viability after 27 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.1274240592048388	[434]	[162,247,NaN]	-1	hSpCas9	negative selection	9543922
72824824	72824847	11	-	27869803	HPAFII	viability after 27 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.2076581185580905	[254]	[102,197,NaN]	1	hSpCas9	negative selection	9543923
72814514	72814537	11	+	27869803	HPAFII	viability after 15 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.4351920768050852	[1001]	[1862,1202,NaN]	5	hSpCas9	negative selection	9626367
72816822	72816845	11	-	27869803	HPAFII	viability after 15 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.36264984618777657	[244]	[390,88,NaN]	-4	hSpCas9	negative selection	9626368
72817738	72817761	11	+	27869803	HPAFII	viability after 15 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.17256332523475743	[229]	[404,199,NaN]	2	hSpCas9	negative selection	9626369
72822221	72822244	11	-	27869803	HPAFII	viability after 15 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.6908358793549267	[91]	[88,43,NaN]	-6	hSpCas9	negative selection	9626370
72822466	72822489	11	+	27869803	HPAFII	viability after 15 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.3608341713189195	[434]	[413,332,NaN]	-4	hSpCas9	negative selection	9626371
72824824	72824847	11	-	27869803	HPAFII	viability after 15 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.5886491058499066	[254]	[614,285,NaN]	6	hSpCas9	negative selection	9626372
72814514	72814537	11	+	27869803	ASPC1	viability after 36 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.03504426976921593	[2448]	[1532,838,434]	0	hSpCas9	negative selection	9708816
72816822	72816845	11	-	27869803	ASPC1	viability after 36 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-1.790452943802701	[810]	[146,124,0]	-9	hSpCas9	negative selection	9708817
72817738	72817761	11	+	27869803	ASPC1	viability after 36 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.39643958619906794	[620]	[333,77,112]	-4	hSpCas9	negative selection	9708818
72822221	72822244	11	-	27869803	ASPC1	viability after 36 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.2729169713600583	[266]	[76,54,93]	-3	hSpCas9	negative selection	9708819
72822466	72822489	11	+	27869803	ASPC1	viability after 36 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.3439207442891523	[953]	[506,554,253]	3	hSpCas9	negative selection	9708820
72824824	72824847	11	-	27869803	ASPC1	viability after 36 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.9368552840602501	[689]	[133,820,399]	8	hSpCas9	negative selection	9708821
72814514	72814537	11	+	27869803	PATU8988S	viability after 35 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.6624656085042271	[2092]	[1648,1017,NaN]	7	hSpCas9	negative selection	9791265
72816822	72816845	11	-	27869803	PATU8988S	viability after 35 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.18427179160058949	[518]	[167,199,NaN]	-2	hSpCas9	negative selection	9791266
72817738	72817761	11	+	27869803	PATU8988S	viability after 35 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.21253253873976335	[587]	[150,257,NaN]	-2	hSpCas9	negative selection	9791267
72822221	72822244	11	-	27869803	PATU8988S	viability after 35 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	0.06656192296337748	[307]	[87,171,NaN]	0	hSpCas9	negative selection	9791268
72822466	72822489	11	+	27869803	PATU8988S	viability after 35 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.8468419496419936	[681]	[502,484,NaN]	8	hSpCas9	negative selection	9791269
72824824	72824847	11	-	27869803	PATU8988S	viability after 35 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.13027035519180502	[680]	[383,215,NaN]	1	hSpCas9	negative selection	9791270
72814514	72814537	11	+	27869803	PATU8988S	viability after 31 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.49103095730018564	[2092]	[1296,1014,NaN]	6	hSpCas9	negative selection	9873714
72816822	72816845	11	-	27869803	PATU8988S	viability after 31 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.1930788481050058	[518]	[107,273,NaN]	-2	hSpCas9	negative selection	9873715
72817738	72817761	11	+	27869803	PATU8988S	viability after 31 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	-0.2532638617035331	[587]	[157,245,NaN]	-3	hSpCas9	negative selection	9873716
72822221	72822244	11	-	27869803	PATU8988S	viability after 31 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-0.2579218630731198	[307]	[41,179,NaN]	-3	hSpCas9	negative selection	9873717
72822466	72822489	11	+	27869803	PATU8988S	viability after 31 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	0.7469842087697768	[681]	[440,475,NaN]	8	hSpCas9	negative selection	9873718
72824824	72824847	11	-	27869803	PATU8988S	viability after 31 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.047580887167564756	[680]	[333,171,NaN]	0	hSpCas9	negative selection	9873719
72814514	72814537	11	+	27869803	HPAFII	viability after 35 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.9386096780604993	[1001]	[531,1467,NaN]	6	hSpCas9	negative selection	9956163
72816822	72816845	11	-	27869803	HPAFII	viability after 35 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.8181154496329308	[244]	[59,81,NaN]	-5	hSpCas9	negative selection	9956164
72817738	72817761	11	+	27869803	HPAFII	viability after 35 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.08142917639802985	[229]	[165,74,NaN]	0	hSpCas9	negative selection	9956165
72822221	72822244	11	-	27869803	HPAFII	viability after 35 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-3.306509279890534	[91]	[7,0,NaN]	-8	hSpCas9	negative selection	9956166
72822466	72822489	11	+	27869803	HPAFII	viability after 35 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.05639657795452635	[434]	[112,322,NaN]	0	hSpCas9	negative selection	9956167
72824824	72824847	11	-	27869803	HPAFII	viability after 35 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	-0.3251554961335742	[254]	[71,137,NaN]	-2	hSpCas9	negative selection	9956168
72814514	72814537	11	+	27869803	HPAFII	viability after 31 days	GCTTCGGGACCGTACGCAAAAGG	ATG16L2	ENSG00000168010	0.7555549374859734	[1001]	[622,1304,NaN]	5	hSpCas9	negative selection	10038612
72816822	72816845	11	-	27869803	HPAFII	viability after 31 days	GACCCACATACACTTACCAGGGG	ATG16L2	ENSG00000168010	-0.8982764709650887	[244]	[90,54,NaN]	-5	hSpCas9	negative selection	10038613
72817738	72817761	11	+	27869803	HPAFII	viability after 31 days	ACTCTGATTGGTTGGCAGGGAGG	ATG16L2	ENSG00000168010	0.35551430812904505	[229]	[201,124,NaN]	2	hSpCas9	negative selection	10038614
72822221	72822244	11	-	27869803	HPAFII	viability after 31 days	GCTGCACGAGCCTCTCCAGCAGG	ATG16L2	ENSG00000168010	-4.33163373950367	[91]	[3,0,NaN]	-9	hSpCas9	negative selection	10038615
72822466	72822489	11	+	27869803	HPAFII	viability after 31 days	TTACCCAACAAGGGCCAAGCAGG	ATG16L2	ENSG00000168010	-0.47300589167758905	[434]	[150,202,NaN]	-3	hSpCas9	negative selection	10038616
72824824	72824847	11	-	27869803	HPAFII	viability after 31 days	TTACCAGCACATCCTGAGCCCGG	ATG16L2	ENSG00000168010	0.05472409049413037	[254]	[95,205,NaN]	0	hSpCas9	negative selection	10038617
72822092	72822115	11	+	28162770	P31FUJ	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-1.1624128765229806	[39]	[20]	-7	hSpCas9	negative selection	10115219
72824074	72824097	11	-	28162770	P31FUJ	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.4024335027880011	[234]	[364]	4	hSpCas9	negative selection	10115220
72825310	72825333	11	-	28162770	P31FUJ	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.28221617596123305	[323]	[462]	3	hSpCas9	negative selection	10115221
72817801	72817824	11	+	28162770	P31FUJ	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.29656797034346	[290]	[419]	3	hSpCas9	negative selection	10115222
72821664	72821687	11	+	28162770	P31FUJ	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.10552032872365236	[139]	[176]	1	hSpCas9	negative selection	10115223
72822113	72822136	11	+	28162770	P31FUJ	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-1.3087510576476773	[233]	[110]	-7	hSpCas9	negative selection	10115224
72822268	72822291	11	+	28162770	P31FUJ	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.4096457909675376	[204]	[319]	4	hSpCas9	negative selection	10115225
72822472	72822495	11	+	28162770	P31FUJ	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.6973466863316499	[200]	[382]	7	hSpCas9	negative selection	10115226
72822493	72822516	11	+	28162770	P31FUJ	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.15073107147534542	[204]	[216]	-1	hSpCas9	negative selection	10115227
72822849	72822872	11	+	28162770	P31FUJ	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.04015712647198266	[342]	[391]	0	hSpCas9	negative selection	10115228
72822092	72822115	11	+	28162770	TF1	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10284585
72824074	72824097	11	-	28162770	TF1	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10284586
72825310	72825333	11	-	28162770	TF1	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10284587
72817801	72817824	11	+	28162770	TF1	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10284588
72821664	72821687	11	+	28162770	TF1	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10284589
72822113	72822136	11	+	28162770	TF1	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10284590
72822268	72822291	11	+	28162770	TF1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[490]	1	hSpCas9	negative selection	10284591
72822472	72822495	11	+	28162770	TF1	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10284592
72822493	72822516	11	+	28162770	TF1	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10284593
72822849	72822872	11	+	28162770	TF1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	NaN	[NaN]	[413]	1	hSpCas9	negative selection	10284594
72822092	72822115	11	+	28162770	SKM1	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-0.9374789154419414	[12]	[11]	-6	hSpCas9	negative selection	10453951
72824074	72824097	11	-	28162770	SKM1	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.12824526678089496	[58]	[113]	1	hSpCas9	negative selection	10453952
72825310	72825333	11	-	28162770	SKM1	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.4675049191729792	[116]	[285]	4	hSpCas9	negative selection	10453953
72817801	72817824	11	+	28162770	SKM1	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	1.0340888905792809	[78]	[285]	8	hSpCas9	negative selection	10453954
72821664	72821687	11	+	28162770	SKM1	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	-0.118983435779137	[42]	[69]	-1	hSpCas9	negative selection	10453955
72822113	72822136	11	+	28162770	SKM1	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-1.0899349032686385	[58]	[48]	-7	hSpCas9	negative selection	10453956
72822268	72822291	11	+	28162770	SKM1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10453957
72822472	72822495	11	+	28162770	SKM1	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.0003389392805181468	[42]	[75]	0	hSpCas9	negative selection	10453958
72822493	72822516	11	+	28162770	SKM1	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.44718493479338356	[38]	[93]	4	hSpCas9	negative selection	10453959
72822849	72822872	11	+	28162770	SKM1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.22636132353939353	[87]	[181]	2	hSpCas9	negative selection	10453960
72822092	72822115	11	+	28162770	SKM1	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-0.9374789154419414	[12]	[11]	-6	hSpCas9	negative selection	10623317
72824074	72824097	11	-	28162770	SKM1	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.12824526678089496	[58]	[113]	1	hSpCas9	negative selection	10623318
72825310	72825333	11	-	28162770	SKM1	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.4675049191729792	[116]	[285]	4	hSpCas9	negative selection	10623319
72817801	72817824	11	+	28162770	SKM1	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	1.0340888905792809	[78]	[285]	8	hSpCas9	negative selection	10623320
72821664	72821687	11	+	28162770	SKM1	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	-0.118983435779137	[42]	[69]	-1	hSpCas9	negative selection	10623321
72822113	72822136	11	+	28162770	SKM1	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-1.0899349032686385	[58]	[48]	-7	hSpCas9	negative selection	10623322
72822268	72822291	11	+	28162770	SKM1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.6429610265885208	[70]	[195]	6	hSpCas9	negative selection	10623323
72822472	72822495	11	+	28162770	SKM1	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.0003389392805181468	[42]	[75]	0	hSpCas9	negative selection	10623324
72822493	72822516	11	+	28162770	SKM1	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.44718493479338356	[38]	[93]	4	hSpCas9	negative selection	10623325
72822849	72822872	11	+	28162770	SKM1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.22636132353939353	[87]	[181]	2	hSpCas9	negative selection	10623326
72822092	72822115	11	+	28162770	PL21	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-2.0477878989542657	[18]	[1]	-8	hSpCas9	negative selection	10792683
72824074	72824097	11	-	28162770	PL21	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.7262084261569078	[124]	[89]	6	hSpCas9	negative selection	10792684
72825310	72825333	11	-	28162770	PL21	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.05329822616004887	[340]	[153]	0	hSpCas9	negative selection	10792685
72817801	72817824	11	+	28162770	PL21	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.7394100245176074	[277]	[201]	6	hSpCas9	negative selection	10792686
72821664	72821687	11	+	28162770	PL21	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.3135214139070625	[158]	[85]	2	hSpCas9	negative selection	10792687
72822113	72822136	11	+	28162770	PL21	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.5630026022359594	[240]	[70]	-4	hSpCas9	negative selection	10792688
72822268	72822291	11	+	28162770	PL21	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.7057796625490707	[161]	[114]	6	hSpCas9	negative selection	10792689
72822472	72822495	11	+	28162770	PL21	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.0947866143430916	[141]	[65]	0	hSpCas9	negative selection	10792690
72822493	72822516	11	+	28162770	PL21	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-1.5906324233726798	[172]	[24]	-7	hSpCas9	negative selection	10792691
72822849	72822872	11	+	28162770	PL21	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.4533262343667668	[244]	[145]	4	hSpCas9	negative selection	10792692
72822092	72822115	11	+	28162770	P31FUJ	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-1.1624128765229806	[39]	[20]	-7	hSpCas9	negative selection	10962049
72824074	72824097	11	-	28162770	P31FUJ	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.4024335027880011	[234]	[364]	4	hSpCas9	negative selection	10962050
72825310	72825333	11	-	28162770	P31FUJ	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.28221617596123305	[323]	[462]	3	hSpCas9	negative selection	10962051
72817801	72817824	11	+	28162770	P31FUJ	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.29656797034346	[290]	[419]	3	hSpCas9	negative selection	10962052
72821664	72821687	11	+	28162770	P31FUJ	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.10552032872365236	[139]	[176]	1	hSpCas9	negative selection	10962053
72822113	72822136	11	+	28162770	P31FUJ	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-1.3087510576476773	[233]	[110]	-7	hSpCas9	negative selection	10962054
72822268	72822291	11	+	28162770	P31FUJ	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.4096457909675376	[204]	[319]	4	hSpCas9	negative selection	10962055
72822472	72822495	11	+	28162770	P31FUJ	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.6973466863316499	[200]	[382]	7	hSpCas9	negative selection	10962056
72822493	72822516	11	+	28162770	P31FUJ	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.15073107147534542	[204]	[216]	-1	hSpCas9	negative selection	10962057
72822849	72822872	11	+	28162770	P31FUJ	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.04015712647198266	[342]	[391]	0	hSpCas9	negative selection	10962058
72822092	72822115	11	+	28162770	OCIAML5	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-5.981349587808964	[34]	[0]	-9	hSpCas9	negative selection	11131415
72824074	72824097	11	-	28162770	OCIAML5	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	-0.3495662303348136	[131]	[186]	-2	hSpCas9	negative selection	11131416
72825310	72825333	11	-	28162770	OCIAML5	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.6337877848442348	[240]	[674]	5	hSpCas9	negative selection	11131417
72817801	72817824	11	+	28162770	OCIAML5	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.1798763216387571	[133]	[273]	1	hSpCas9	negative selection	11131418
72821664	72821687	11	+	28162770	OCIAML5	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	-0.5091788573409887	[81]	[103]	-4	hSpCas9	negative selection	11131419
72822113	72822136	11	+	28162770	OCIAML5	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.8341446628667346	[79]	[80]	-5	hSpCas9	negative selection	11131420
72822268	72822291	11	+	28162770	OCIAML5	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.698987240859608	[133]	[148]	-4	hSpCas9	negative selection	11131421
72822472	72822495	11	+	28162770	OCIAML5	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.16018886622632883	[116]	[188]	-1	hSpCas9	negative selection	11131422
72822493	72822516	11	+	28162770	OCIAML5	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.811136306809115	[138]	[142]	-5	hSpCas9	negative selection	11131423
72822849	72822872	11	+	28162770	OCIAML5	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.3566861739300311	[166]	[385]	3	hSpCas9	negative selection	11131424
72822092	72822115	11	+	28162770	EOL1	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-1.7245450665703372	[68]	[10]	-8	hSpCas9	negative selection	11300781
72824074	72824097	11	-	28162770	EOL1	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.8122815393196223	[186]	[172]	7	hSpCas9	negative selection	11300782
72825310	72825333	11	-	28162770	EOL1	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.46864784390349046	[560]	[408]	4	hSpCas9	negative selection	11300783
72817801	72817824	11	+	28162770	EOL1	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.8453639329600512	[542]	[513]	7	hSpCas9	negative selection	11300784
72821664	72821687	11	+	28162770	EOL1	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	-0.2782691114291527	[243]	[105]	-2	hSpCas9	negative selection	11300785
72822113	72822136	11	+	28162770	EOL1	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.9097741980873391	[377]	[105]	-6	hSpCas9	negative selection	11300786
72822268	72822291	11	+	28162770	EOL1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.1663607246276757	[261]	[122]	-1	hSpCas9	negative selection	11300787
72822472	72822495	11	+	28162770	EOL1	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.1558733176769901	[183]	[107]	1	hSpCas9	negative selection	11300788
72822493	72822516	11	+	28162770	EOL1	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.771844510656809	[228]	[205]	6	hSpCas9	negative selection	11300789
72822849	72822872	11	+	28162770	EOL1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	1.2752348594393208	[297]	[379]	9	hSpCas9	negative selection	11300790
72822092	72822115	11	+	28162770	MOLM13	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-1.1892229049324126	[40]	[12]	-6	hSpCas9	negative selection	11470147
72824074	72824097	11	-	28162770	MOLM13	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.4533165804573063	[198]	[196]	3	hSpCas9	negative selection	11470148
72825310	72825333	11	-	28162770	MOLM13	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.35140363906372685	[476]	[439]	2	hSpCas9	negative selection	11470149
72817801	72817824	11	+	28162770	MOLM13	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.41239426895287534	[476]	[458]	3	hSpCas9	negative selection	11470150
72821664	72821687	11	+	28162770	MOLM13	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	1.204854975710785	[176]	[294]	8	hSpCas9	negative selection	11470151
72822113	72822136	11	+	28162770	MOLM13	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-1.2570033803210525	[237]	[71]	-6	hSpCas9	negative selection	11470152
72822268	72822291	11	+	28162770	MOLM13	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	1.1643759063557146	[252]	[409]	8	hSpCas9	negative selection	11470153
72822472	72822495	11	+	28162770	MOLM13	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.0665268191628115	[209]	[158]	0	hSpCas9	negative selection	11470154
72822493	72822516	11	+	28162770	MOLM13	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.02658258522867002	[223]	[158]	0	hSpCas9	negative selection	11470155
72822849	72822872	11	+	28162770	MOLM13	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.7614725946067109	[414]	[176]	-4	hSpCas9	negative selection	11470156
72822092	72822115	11	+	28162770	HEL	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-4.605188681443229	[37]	[0]	-9	hSpCas9	negative selection	11639513
72824074	72824097	11	-	28162770	HEL	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.35323221480537215	[164]	[134]	3	hSpCas9	negative selection	11639514
72825310	72825333	11	-	28162770	HEL	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.48831016688121276	[462]	[415]	4	hSpCas9	negative selection	11639515
72817801	72817824	11	+	28162770	HEL	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.24346864857982975	[363]	[275]	2	hSpCas9	negative selection	11639516
72821664	72821687	11	+	28162770	HEL	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.5766496415425845	[133]	[127]	5	hSpCas9	negative selection	11639517
72822113	72822136	11	+	28162770	HEL	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.7125924211542192	[283]	[110]	-4	hSpCas9	negative selection	11639518
72822268	72822291	11	+	28162770	HEL	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.7369891577964081	[236]	[252]	6	hSpCas9	negative selection	11639519
72822472	72822495	11	+	28162770	HEL	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.18330721336305977	[164]	[119]	1	hSpCas9	negative selection	11639520
72822493	72822516	11	+	28162770	HEL	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-1.0899772891644914	[225]	[67]	-6	hSpCas9	negative selection	11639521
72822849	72822872	11	+	28162770	HEL	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	0.0484685890529728	[310]	[205]	0	hSpCas9	negative selection	11639522
72822092	72822115	11	+	28162770	MV411	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-5.307151300894862	[46]	[0]	-9	hSpCas9	negative selection	11808879
72824074	72824097	11	-	28162770	MV411	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.2630344058337938	[91]	[92]	2	hSpCas9	negative selection	11808880
72825310	72825333	11	-	28162770	MV411	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	-0.23436896070876956	[397]	[284]	-2	hSpCas9	negative selection	11808881
72817801	72817824	11	+	28162770	MV411	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	-0.9105148089934612	[269]	[120]	-6	hSpCas9	negative selection	11808882
72821664	72821687	11	+	28162770	MV411	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	-0.3051034722460033	[109]	[74]	-2	hSpCas9	negative selection	11808883
72822113	72822136	11	+	28162770	MV411	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.3327557057905088	[150]	[100]	-3	hSpCas9	negative selection	11808884
72822268	72822291	11	+	28162770	MV411	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.3688210804279195	[232]	[151]	-3	hSpCas9	negative selection	11808885
72822472	72822495	11	+	28162770	MV411	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.8135410242526155	[153]	[227]	7	hSpCas9	negative selection	11808886
72822493	72822516	11	+	28162770	MV411	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-0.005848878499456256	[117]	[98]	0	hSpCas9	negative selection	11808887
72822849	72822872	11	+	28162770	MV411	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.3981877318450053	[254]	[162]	-3	hSpCas9	negative selection	11808888
72822092	72822115	11	+	28162770	MONOMAC1	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-2.4771447662522883	[33]	[6]	-9	hSpCas9	negative selection	11978245
72824074	72824097	11	-	28162770	MONOMAC1	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	0.638152283194776	[87]	[156]	6	hSpCas9	negative selection	11978246
72825310	72825333	11	-	28162770	MONOMAC1	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.014772235419066915	[214]	[248]	0	hSpCas9	negative selection	11978247
72817801	72817824	11	+	28162770	MONOMAC1	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.9585328614056886	[201]	[449]	8	hSpCas9	negative selection	11978248
72821664	72821687	11	+	28162770	MONOMAC1	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.02114332298997973	[97]	[113]	0	hSpCas9	negative selection	11978249
72822113	72822136	11	+	28162770	MONOMAC1	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	0.04769674203129629	[118]	[140]	0	hSpCas9	negative selection	11978250
72822268	72822291	11	+	28162770	MONOMAC1	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-1.0506473600780304	[102]	[56]	-7	hSpCas9	negative selection	11978251
72822472	72822495	11	+	28162770	MONOMAC1	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-0.1638699831243544	[85]	[87]	-1	hSpCas9	negative selection	11978252
72822493	72822516	11	+	28162770	MONOMAC1	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.8100179104743969	[101]	[204]	7	hSpCas9	negative selection	11978253
72822849	72822872	11	+	28162770	MONOMAC1	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.09918952366140898	[170]	[182]	-1	hSpCas9	negative selection	11978254
72822092	72822115	11	+	28162770	OCIAML2	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	0.33672509681544316	[2]	[20]	3	hSpCas9	negative selection	12147611
72824074	72824097	11	-	28162770	OCIAML2	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	-0.43820834754978355	[21]	[89]	-3	hSpCas9	negative selection	12147612
72825310	72825333	11	-	28162770	OCIAML2	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	0.21119421473158395	[71]	[461]	2	hSpCas9	negative selection	12147613
72817801	72817824	11	+	28162770	OCIAML2	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	0.5148706050627236	[49]	[395]	5	hSpCas9	negative selection	12147614
72821664	72821687	11	+	28162770	OCIAML2	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.4107256782592198	[18]	[139]	4	hSpCas9	negative selection	12147615
72822113	72822136	11	+	28162770	OCIAML2	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	-0.12893847553336907	[28]	[146]	-1	hSpCas9	negative selection	12147616
72822268	72822291	11	+	28162770	OCIAML2	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	0.22166671959031659	[40]	[264]	2	hSpCas9	negative selection	12147617
72822472	72822495	11	+	28162770	OCIAML2	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	0.9184124655037381	[20]	[219]	8	hSpCas9	negative selection	12147618
72822493	72822516	11	+	28162770	OCIAML2	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	-1.1487017303547988	[21]	[54]	-6	hSpCas9	negative selection	12147619
72822849	72822872	11	+	28162770	OCIAML2	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.6164806917056161	[38]	[140]	-5	hSpCas9	negative selection	12147620
72822092	72822115	11	+	28162770	OCIAML3	viability	GCAGCAGGCCCAGCAGGTGGAGG	ATG16L2	ENSG00000168010	-4.401362562381768	[13]	[1]	-9	hSpCas9	negative selection	12316977
72824074	72824097	11	-	28162770	OCIAML3	viability	ACAGTGGGACAGCGTCAGGGAGG	ATG16L2	ENSG00000168010	-0.22585652867615524	[42]	[110]	-2	hSpCas9	negative selection	12316978
72825310	72825333	11	-	28162770	OCIAML3	viability	GAACAGCATTGACCTCAGAGAGG	ATG16L2	ENSG00000168010	-0.2751199997568521	[94]	[236]	-2	hSpCas9	negative selection	12316979
72817801	72817824	11	+	28162770	OCIAML3	viability	ACTGAGGGTGAAGTGGCAGGAGG	ATG16L2	ENSG00000168010	-0.7148620351985489	[111]	[205]	-5	hSpCas9	negative selection	12316980
72821664	72821687	11	+	28162770	OCIAML3	viability	CCAGATGGCCTACCAGGTGGTGG	ATG16L2	ENSG00000168010	0.7014482432020082	[32]	[161]	6	hSpCas9	negative selection	12316981
72822113	72822136	11	+	28162770	OCIAML3	viability	GGAGTGGCGGGCGCAGAATGCGG	ATG16L2	ENSG00000168010	0.10284774046789036	[61]	[200]	1	hSpCas9	negative selection	12316982
72822268	72822291	11	+	28162770	OCIAML3	viability	GCAACCTGCGCAACGAGCGCCGG	ATG16L2	ENSG00000168010	-0.14334623131459798	[44]	[122]	-1	hSpCas9	negative selection	12316983
72822472	72822495	11	+	28162770	OCIAML3	viability	AACAAGGGCCAAGCAGGCGCGGG	ATG16L2	ENSG00000168010	-1.0400720352236315	[46]	[68]	-6	hSpCas9	negative selection	12316984
72822493	72822516	11	+	28162770	OCIAML3	viability	GGTGTCCCAGGAGCTGAAGAAGG	ATG16L2	ENSG00000168010	0.0708081680862076	[40]	[129]	0	hSpCas9	negative selection	12316985
72822849	72822872	11	+	28162770	OCIAML3	viability	GGCCCGGACACCCTAGGCGATGG	ATG16L2	ENSG00000168010	-0.34864188258337575	[88]	[210]	-3	hSpCas9	negative selection	12316986