Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 525
• Symbol: ATP6V1B1
• Description: ATPase H+ transporting V1 subunit B1

DataSource: http://genomecrispr.dkfz.de/#!/results/ATP6V1B1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
70935990	70936013	2	-	26627737	DLD1	viability	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.20963610886375128	[717]	[615,153,37]	2	hSpCas9	negative selection	812543
70935990	70936013	2	-	26627737	GBM cells	viability after 5 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.3285899602683618	[376]	[187,133]	-5	hSpCas9	negative selection	894858
70935990	70936013	2	-	26627737	GBM cells	viability after 13 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.380548655269709	[376]	[203,118]	-4	hSpCas9	negative selection	977173
70935990	70936013	2	-	26627737	GBM cells	viability after 21 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.6685764841222251	[376]	[143,114]	-5	hSpCas9	negative selection	1059488
70935990	70936013	2	-	26627737	RPE1	viability after 9 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.5639508841022283	[971]	[128,304]	-4	hSpCas9	negative selection	1141803
70935990	70936013	2	-	26627737	RPE1	viability after 12 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.19581107776790124	[971]	[227,227]	-1	hSpCas9	negative selection	1224118
70935990	70936013	2	-	26627737	RPE1	viability after 15 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.710318839603117	[971]	[108,224]	-4	hSpCas9	negative selection	1306433
70935990	70936013	2	-	26627737	RPE1	viability after 18 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.02788016381271724	[971]	[177,362]	0	hSpCas9	negative selection	1388748
70935990	70936013	2	-	26627737	HeLa	viability after 8 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.7484995896125821	[534]	[139,240,41]	-6	hSpCas9	negative selection	1471063
70935990	70936013	2	-	26627737	HeLa	viability after 12 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.014382888789429116	[534]	[253,272,124]	0	hSpCas9	negative selection	1553378
70935990	70936013	2	-	26627737	HeLa	viability after 15 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.4210691745008813	[534]	[36,212,245]	-4	hSpCas9	negative selection	1635693
70935990	70936013	2	-	26627737	HeLa	viability after 18 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.433530814721835	[534]	[23,173,245]	-4	hSpCas9	negative selection	1718008
70935990	70936013	2	-	26627737	HCT116	viability after 6 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.7855248118432554	[951]	[71,94]	-4	hSpCas9	negative selection	1800323
70935990	70936013	2	-	26627737	HCT116	viability after 8 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.169858209418766	[243]	[171,120,160]	2	hSpCas9	negative selection	1882638
70935990	70936013	2	-	26627737	HCT116	viability after 9 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.08320815785606883	[951]	[206,265]	0	hSpCas9	negative selection	1964953
70935990	70936013	2	-	26627737	HCT116	viability after 12 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.10378920851689394	[243]	[109,44,201]	-1	hSpCas9	negative selection	2047268
70935990	70936013	2	-	26627737	HCT116	viability after 15 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.10835731001109822	[243]	[145,39,204]	-1	hSpCas9	negative selection	2129583
70935990	70936013	2	-	26627737	HCT116	viability after 18 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.24964433660030588	[243]	[154,21,126]	-2	hSpCas9	negative selection	2211898
70935990	70936013	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.23572798213612328	[2,2]	[3,2]	5	hSpCas9	positive selection	2972498
70935990	70936013	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.06532163258252607	[2,2]	[1,2]	1	hSpCas9	positive selection	3040356
70935990	70936013	2	-	26780180	HT29	viability (Avana library 4 designs)	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	2.26749334067859	[]	[]	7	hSpCas9	negative selection	3408649
70935990	70936013	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.4282599263822	[]	[]	0	hSpCas9	negative selection	3482291
70935990	70936013	2	-	26780180	A375	viability (Avana lentiGuide)	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	9.28798338553757	[]	[]	6	hSpCas9	negative selection	3590950
70935990	70936013	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.19068087568298592	[4]	[5,5]	5	hSpCas9	positive selection	3699609
70935990	70936013	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.2598139668983606	[4]	[1,3]	-4	hSpCas9	positive selection	3808216
70936062	70936084	2	-	27760321	OCIAML3	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	-0.5126151574511926	[788,571]	[371,365]	-5	hSpCas9	negative selection	4380671
70936062	70936084	2	-	27760321	OCIAML2	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	-0.3757523747365989	[788,571]	[382,468]	-4	hSpCas9	negative selection	4464134
70936062	70936084	2	-	27760321	MV411	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	-0.11505516322665421	[788,571]	[380,454]	-1	hSpCas9	negative selection	4547597
70936062	70936084	2	-	27760321	HL60	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.20623141003294754	[788,571]	[701,563]	2	hSpCas9	negative selection	4631060
70936062	70936084	2	-	27760321	HT1080	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.7967066400104893	[571,446]	[354,349]	4	hSpCas9	negative selection	4714523
70936062	70936084	2	-	27760321	HT29	viability after 7 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.147160358722761	[571,446]	[946,662,600]	2	hSpCas9	negative selection	4797986
70936062	70936084	2	-	27760321	HT29	viability after 25 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.29820333907789054	[571,446]	[680,658,819]	3	hSpCas9	negative selection	4881449
70936062	70936084	2	-	27760321	HT29	viability after 22 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.2174857918579809	[571,446]	[599,662,794]	2	hSpCas9	negative selection	4964912
70936062	70936084	2	-	27760321	HT29	viability after 19 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.5348757018735318	[571,446]	[564,501,1413]	5	hSpCas9	negative selection	5048375
70936062	70936084	2	-	27760321	HT29	viability after 16 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.46611010378784734	[571,446]	[483,1004,838]	5	hSpCas9	negative selection	5131838
70936062	70936084	2	-	27760321	HT29	viability after 13 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.11972904055097355	[571,446]	[567,769,591]	1	hSpCas9	negative selection	5215301
70936062	70936084	2	-	27760321	HT29	viability after 10 days	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.040551904525681914	[571,446]	[424,959,587]	0	hSpCas9	negative selection	5298764
70936062	70936084	2	-	27760321	MOLM13	viability	GGGCTACTCACTGACACGGGGG	ATP6V1B1	ENSG00000116039	0.2818865654458138	[788,571]	[445,475]	2	hSpCas9	negative selection	5382227
70935964	70935987	2	+	27661255	K562	viability	GAGATAGACAGCAGGCCTGGGGG	ATP6V1B1	ENSG00000116039	0.10493719567729948	[797,808]	[688,690]	3	dCas9-KRAB	negative selection	5464306
70936091	70936114	2	+	27661255	K562	viability	GTGACGGGTGAGGTCAGGGTGGG	ATP6V1B1	ENSG00000116039	0.1847816894757552	[663,733]	[700,575]	6	dCas9-KRAB	negative selection	5464307
70936351	70936374	2	-	27661255	K562	viability	GGGCAACTGGAAGCTATCTCTGG	ATP6V1B1	ENSG00000116039	0.32929738922962337	[117,277]	[204,187]	9	dCas9-KRAB	negative selection	5464308
70935990	70936013	2	-	27869803	HPAFII	viability after 27 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-1.3345497238879762	[463]	[33,148,NaN]	-7	hSpCas9	negative selection	9575603
70935990	70936013	2	-	27869803	HPAFII	viability after 15 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.6353669885890489	[463]	[341,307,NaN]	-6	hSpCas9	negative selection	9658052
70935990	70936013	2	-	27869803	ASPC1	viability after 36 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.7897456723929176	[850]	[476,637,434]	7	hSpCas9	negative selection	9740501
70935990	70936013	2	-	27869803	PATU8988S	viability after 35 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.3306588936916712	[766]	[160,616,NaN]	4	hSpCas9	negative selection	9822950
70935990	70936013	2	-	27869803	PATU8988S	viability after 31 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	0.5993334538924138	[766]	[205,790,NaN]	7	hSpCas9	negative selection	9905399
70935990	70936013	2	-	27869803	HPAFII	viability after 35 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-0.675522019035321	[463]	[52,252,NaN]	-4	hSpCas9	negative selection	9987848
70935990	70936013	2	-	27869803	HPAFII	viability after 31 days	CTAGGTTGCAGCTACTGCCGGGG	ATP6V1B1	ENSG00000116039	-1.3001933920970605	[463]	[32,184,NaN]	-7	hSpCas9	negative selection	10070297