Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10195
• Symbol: Alg3
• Description: ALG3 alpha-1,3- mannosyltransferase

DataSource: http://genomecrispr.dkfz.de/#!/results/Alg3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
184245289	184245312	3	+	26472758	Jiyoye	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-1.306261677164092	[222]	[67]	-7	hSpCas9	negative selection	5419
184243924	184243947	3	+	26472758	Jiyoye	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.3197125402555341	[16]	[15]	2	hSpCas9	negative selection	5420
184245271	184245294	3	-	26472758	Jiyoye	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.4408215250490767	[188]	[104]	-3	hSpCas9	negative selection	5421
184243940	184243963	3	+	26472758	Jiyoye	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.09275101535948349	[139]	[98]	0	hSpCas9	negative selection	5422
184242830	184242853	3	-	26472758	Jiyoye	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.9553946978788348	[17]	[6]	-6	hSpCas9	negative selection	5423
184245777	184245800	3	-	26472758	Jiyoye	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.5624536069837842	[131]	[146]	4	hSpCas9	negative selection	5424
184245542	184245565	3	-	26472758	Jiyoye	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.9851420412728871	[41]	[15]	-6	hSpCas9	negative selection	5425
184245248	184245271	3	+	26472758	Jiyoye	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.257957467899266	[110]	[34]	-7	hSpCas9	negative selection	5426
184243813	184243836	3	+	26472758	Jiyoye	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	1.2504498778184203	[67]	[121]	7	hSpCas9	negative selection	5427
184244612	184244635	3	+	26472758	Jiyoye	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	0.5208321633014406	[60]	[65]	4	hSpCas9	negative selection	5428
184245289	184245312	3	+	26472758	KBM7	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.2658479271302977	[564,513]	[182,235]	-3	hSpCas9	negative selection	196537
184243924	184243947	3	+	26472758	KBM7	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.11127425913563194	[89,134]	[56,59]	1	hSpCas9	negative selection	196538
184245271	184245294	3	-	26472758	KBM7	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.42711714520619853	[634,410]	[183,175]	-4	hSpCas9	negative selection	196539
184243940	184243963	3	+	26472758	KBM7	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.5128273206632606	[425,288]	[154,308]	5	hSpCas9	negative selection	196540
184242830	184242853	3	-	26472758	KBM7	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	1.6976684242995144	[43,28]	[77,33]	9	hSpCas9	negative selection	196541
184245777	184245800	3	-	26472758	KBM7	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.03448480545883234	[730,359]	[257,251]	0	hSpCas9	negative selection	196542
184245542	184245565	3	-	26472758	KBM7	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.0891532087818265	[173,152]	[176,150]	9	hSpCas9	negative selection	196543
184245248	184245271	3	+	26472758	KBM7	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.45728836108592785	[467,668]	[148,243]	-4	hSpCas9	negative selection	196544
184243813	184243836	3	+	26472758	KBM7	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.7033086785614115	[361,380]	[115,100]	-5	hSpCas9	negative selection	196545
184244612	184244635	3	+	26472758	KBM7	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.48575627788467235	[281,386]	[120,108]	-4	hSpCas9	negative selection	196546
184245289	184245312	3	+	26472758	Raji	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.17755035203156122	[384]	[78]	-1	hSpCas9	negative selection	387655
184243924	184243947	3	+	26472758	Raji	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-1.204202615292304	[138]	[13]	-7	hSpCas9	negative selection	387656
184245271	184245294	3	-	26472758	Raji	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.183332388606898	[147]	[77]	9	hSpCas9	negative selection	387657
184243940	184243963	3	+	26472758	Raji	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.6999713866840046	[181]	[25]	-5	hSpCas9	negative selection	387658
184242830	184242853	3	-	26472758	Raji	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.8926164646264008	[7]	[0]	-6	hSpCas9	negative selection	387659
184245777	184245800	3	-	26472758	Raji	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.21686201217209244	[240]	[64]	2	hSpCas9	negative selection	387660
184245542	184245565	3	-	26472758	Raji	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.7609331213521682	[88]	[34]	7	hSpCas9	negative selection	387661
184245248	184245271	3	+	26472758	Raji	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.7153466125709205	[282]	[39]	-5	hSpCas9	negative selection	387662
184243813	184243836	3	+	26472758	Raji	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.6702240432899527	[239]	[34]	-5	hSpCas9	negative selection	387663
184244612	184244635	3	+	26472758	Raji	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.7745607031046882	[257]	[34]	-5	hSpCas9	negative selection	387664
184245289	184245312	3	+	26472758	K562	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	0.22017118141976955	[479]	[471]	1	hSpCas9	negative selection	578773
184243924	184243947	3	+	26472758	K562	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.8131527665957169	[148]	[220]	6	hSpCas9	negative selection	578774
184245271	184245294	3	-	26472758	K562	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.26285597592312304	[310]	[314]	2	hSpCas9	negative selection	578775
184243940	184243963	3	+	26472758	K562	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.5230218248401064	[302]	[177]	-3	hSpCas9	negative selection	578776
184242830	184242853	3	-	26472758	K562	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	1.2988665116888236	[12]	[26]	9	hSpCas9	negative selection	578777
184245777	184245800	3	-	26472758	K562	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.6453810417335679	[411]	[543]	5	hSpCas9	negative selection	578778
184245542	184245565	3	-	26472758	K562	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.3218974803441641	[144]	[152]	2	hSpCas9	negative selection	578779
184245248	184245271	3	+	26472758	K562	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	0.04464921529066947	[347]	[302]	0	hSpCas9	negative selection	578780
184243813	184243836	3	+	26472758	K562	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-1.6646076122860625	[337]	[89]	-7	hSpCas9	negative selection	578781
184244612	184244635	3	+	26472758	K562	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.5454264261027081	[388]	[224]	-3	hSpCas9	negative selection	578782
184243891	184243914	3	+	26627737	DLD1	viability	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-1.4205715752558963	[513]	[57,130,2]	-8	hSpCas9	negative selection	820693
184245271	184245294	3	-	26627737	DLD1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.7804242442293416	[77]	[67,105,78]	9	hSpCas9	negative selection	820694
184245542	184245565	3	-	26627737	DLD1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.06711735813773267	[845]	[143,328,282]	0	hSpCas9	negative selection	820695
184245722	184245745	3	-	26627737	DLD1	viability	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.3375362363650464	[490]	[314,199,83]	3	hSpCas9	negative selection	820696
184248930	184248953	3	-	26627737	DLD1	viability	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.6815937065806241	[233]	[134,161,64]	6	hSpCas9	negative selection	820697
184249256	184249279	3	-	26627737	DLD1	viability	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.387512964629386	[272]	[133,59,134]	4	hSpCas9	negative selection	820698
184243891	184243914	3	+	26627737	GBM cells	viability after 5 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.41347044733080607	[225]	[89,91]	-6	hSpCas9	negative selection	903008
184245271	184245294	3	-	26627737	GBM cells	viability after 5 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.1020057402631969	[42]	[46,51]	9	hSpCas9	negative selection	903009
184245542	184245565	3	-	26627737	GBM cells	viability after 5 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.4066199436971245	[357]	[262,245]	6	hSpCas9	negative selection	903010
184245722	184245745	3	-	26627737	GBM cells	viability after 5 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.5383241596292182	[207]	[122,200]	7	hSpCas9	negative selection	903011
184248930	184248953	3	-	26627737	GBM cells	viability after 5 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.04634316051988252	[180]	[127,59]	0	hSpCas9	negative selection	903012
184249256	184249279	3	-	26627737	GBM cells	viability after 5 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.3915359885285088	[169]	[65,72]	-6	hSpCas9	negative selection	903013
184243891	184243914	3	+	26627737	GBM cells	viability after 13 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-1.1428956307252385	[225]	[81,33]	-8	hSpCas9	negative selection	985323
184245271	184245294	3	-	26627737	GBM cells	viability after 13 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.6192660633493505	[42]	[58,16]	7	hSpCas9	negative selection	985324
184245542	184245565	3	-	26627737	GBM cells	viability after 13 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.08478787349740935	[357]	[205,205]	1	hSpCas9	negative selection	985325
184245722	184245745	3	-	26627737	GBM cells	viability after 13 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.5213169495430436	[207]	[113,200]	6	hSpCas9	negative selection	985326
184248930	184248953	3	-	26627737	GBM cells	viability after 13 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.25322182752490696	[180]	[120,50]	-3	hSpCas9	negative selection	985327
184249256	184249279	3	-	26627737	GBM cells	viability after 13 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.2336133148410413	[169]	[78,77]	-3	hSpCas9	negative selection	985328
184243891	184243914	3	+	26627737	GBM cells	viability after 21 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-1.0445891784095647	[225]	[58,59]	-7	hSpCas9	negative selection	1067638
184245271	184245294	3	-	26627737	GBM cells	viability after 21 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.5319710569148335	[42]	[38,28]	5	hSpCas9	negative selection	1067639
184245542	184245565	3	-	26627737	GBM cells	viability after 21 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.8210574207319097	[357]	[107,111]	-6	hSpCas9	negative selection	1067640
184245722	184245745	3	-	26627737	GBM cells	viability after 21 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.20068094794838978	[207]	[132,126]	2	hSpCas9	negative selection	1067641
184248930	184248953	3	-	26627737	GBM cells	viability after 21 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.844093752531948	[180]	[59,49]	-6	hSpCas9	negative selection	1067642
184249256	184249279	3	-	26627737	GBM cells	viability after 21 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.16108775998996006	[169]	[91,73]	-1	hSpCas9	negative selection	1067643
184243891	184243914	3	+	26627737	RPE1	viability after 9 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.5596154923454073	[602]	[107,153]	-4	hSpCas9	negative selection	1149953
184245271	184245294	3	-	26627737	RPE1	viability after 9 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.23604284615008966	[779]	[188,230]	-2	hSpCas9	negative selection	1149954
184245542	184245565	3	-	26627737	RPE1	viability after 9 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.5231037370725657	[903]	[953,631]	8	hSpCas9	negative selection	1149955
184245722	184245745	3	-	26627737	RPE1	viability after 9 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.06302944197831595	[1060]	[346,346]	0	hSpCas9	negative selection	1149956
184248930	184248953	3	-	26627737	RPE1	viability after 9 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.8087367558316138	[453]	[327,146]	5	hSpCas9	negative selection	1149957
184249256	184249279	3	-	26627737	RPE1	viability after 9 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.7235531558331574	[431]	[197,255]	5	hSpCas9	negative selection	1149958
184243891	184243914	3	+	26627737	RPE1	viability after 12 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.18349460584182092	[602]	[147,136]	-1	hSpCas9	negative selection	1232268
184245271	184245294	3	-	26627737	RPE1	viability after 12 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.06901244952084089	[779]	[157,243]	0	hSpCas9	negative selection	1232269
184245542	184245565	3	-	26627737	RPE1	viability after 12 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.6041353677262669	[903]	[954,508]	8	hSpCas9	negative selection	1232270
184245722	184245745	3	-	26627737	RPE1	viability after 12 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.7658082214098413	[1060]	[490,477]	5	hSpCas9	negative selection	1232271
184248930	184248953	3	-	26627737	RPE1	viability after 12 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.36864008014154764	[453]	[173,139]	2	hSpCas9	negative selection	1232272
184249256	184249279	3	-	26627737	RPE1	viability after 12 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.0960849031798473	[431]	[125,121]	0	hSpCas9	negative selection	1232273
184243891	184243914	3	+	26627737	RPE1	viability after 15 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.2805128666345687	[602]	[115,163]	-2	hSpCas9	negative selection	1314583
184245271	184245294	3	-	26627737	RPE1	viability after 15 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.7143860475616575	[779]	[163,105]	-4	hSpCas9	negative selection	1314584
184245542	184245565	3	-	26627737	RPE1	viability after 15 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.6256706406338826	[903]	[1147,442]	8	hSpCas9	negative selection	1314585
184245722	184245745	3	-	26627737	RPE1	viability after 15 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.17148059205024052	[1060]	[350,184]	-1	hSpCas9	negative selection	1314586
184248930	184248953	3	-	26627737	RPE1	viability after 15 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.344456784500094	[453]	[148,54]	-2	hSpCas9	negative selection	1314587
184249256	184249279	3	-	26627737	RPE1	viability after 15 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	1.0169190863334616	[431]	[230,262]	6	hSpCas9	negative selection	1314588
184243891	184243914	3	+	26627737	RPE1	viability after 18 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-1.0132647879254868	[602]	[54,107]	-6	hSpCas9	negative selection	1396898
184245271	184245294	3	-	26627737	RPE1	viability after 18 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.49103299748094037	[779]	[113,187]	-3	hSpCas9	negative selection	1396899
184245542	184245565	3	-	26627737	RPE1	viability after 18 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.6184937691523364	[903]	[984,496]	8	hSpCas9	negative selection	1396900
184245722	184245745	3	-	26627737	RPE1	viability after 18 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.196166699526997	[1060]	[276,220]	-1	hSpCas9	negative selection	1396901
184248930	184248953	3	-	26627737	RPE1	viability after 18 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.10050407685076446	[453]	[170,88]	0	hSpCas9	negative selection	1396902
184249256	184249279	3	-	26627737	RPE1	viability after 18 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.6235156635026564	[431]	[109,253]	4	hSpCas9	negative selection	1396903
184243891	184243914	3	+	26627737	HeLa	viability after 8 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.6379441511635129	[543]	[318,79,97]	-6	hSpCas9	negative selection	1479213
184245271	184245294	3	-	26627737	HeLa	viability after 8 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.4149907899731398	[213]	[211,247,274]	8	hSpCas9	negative selection	1479214
184245542	184245565	3	-	26627737	HeLa	viability after 8 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.8137921224271841	[375]	[365,121,384]	6	hSpCas9	negative selection	1479215
184245722	184245745	3	-	26627737	HeLa	viability after 8 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.43409056384693623	[357]	[30,86,202]	-4	hSpCas9	negative selection	1479216
184248930	184248953	3	-	26627737	HeLa	viability after 8 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	1.0262741485879308	[174]	[371,29,113]	7	hSpCas9	negative selection	1479217
184249256	184249279	3	-	26627737	HeLa	viability after 8 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-1.0891516977503783	[379]	[88,88,58]	-8	hSpCas9	negative selection	1479218
184243891	184243914	3	+	26627737	HeLa	viability after 12 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.7105491934502781	[543]	[75,187,140]	-6	hSpCas9	negative selection	1561528
184245271	184245294	3	-	26627737	HeLa	viability after 12 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.6764344621839178	[213]	[2,197,212]	5	hSpCas9	negative selection	1561529
184245542	184245565	3	-	26627737	HeLa	viability after 12 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.6512333716127908	[375]	[264,231,236]	5	hSpCas9	negative selection	1561530
184245722	184245745	3	-	26627737	HeLa	viability after 12 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.43236416401306443	[357]	[36,69,223]	-4	hSpCas9	negative selection	1561531
184248930	184248953	3	-	26627737	HeLa	viability after 12 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	1.3707986397529572	[174]	[118,291,136]	8	hSpCas9	negative selection	1561532
184249256	184249279	3	-	26627737	HeLa	viability after 12 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.3938191170469843	[379]	[89,97,171]	-4	hSpCas9	negative selection	1561533
184243891	184243914	3	+	26627737	HeLa	viability after 15 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.127889124218598	[543]	[279,160,162]	-1	hSpCas9	negative selection	1643843
184245271	184245294	3	-	26627737	HeLa	viability after 15 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.2701957017588189	[213]	[22,154,140]	2	hSpCas9	negative selection	1643844
184245542	184245565	3	-	26627737	HeLa	viability after 15 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.8912914970660745	[375]	[328,324,189]	6	hSpCas9	negative selection	1643845
184245722	184245745	3	-	26627737	HeLa	viability after 15 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.7531604010649521	[357]	[182,293,261]	6	hSpCas9	negative selection	1643846
184248930	184248953	3	-	26627737	HeLa	viability after 15 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.07489667599191963	[174]	[76,103,17]	0	hSpCas9	negative selection	1643847
184249256	184249279	3	-	26627737	HeLa	viability after 15 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-2.373831351316331	[379]	[0,57,30]	-9	hSpCas9	negative selection	1643848
184243891	184243914	3	+	26627737	HeLa	viability after 18 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-0.1571694692403277	[543]	[176,136,162]	-1	hSpCas9	negative selection	1726158
184245271	184245294	3	-	26627737	HeLa	viability after 18 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.3001847329225863	[213]	[15,132,140]	2	hSpCas9	negative selection	1726159
184245542	184245565	3	-	26627737	HeLa	viability after 18 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.8791323674047391	[375]	[224,257,189]	6	hSpCas9	negative selection	1726160
184245722	184245745	3	-	26627737	HeLa	viability after 18 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.7623739973523395	[357]	[118,251,261]	6	hSpCas9	negative selection	1726161
184248930	184248953	3	-	26627737	HeLa	viability after 18 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.1625569142100134	[174]	[47,80,17]	-1	hSpCas9	negative selection	1726162
184249256	184249279	3	-	26627737	HeLa	viability after 18 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-2.3465411057957373	[379]	[0,48,30]	-9	hSpCas9	negative selection	1726163
184243891	184243914	3	+	26627737	HCT116	viability after 6 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	3.1144115352051385	[272]	[983,33]	9	hSpCas9	negative selection	1808473
184245271	184245294	3	-	26627737	HCT116	viability after 6 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.952839177380843	[358]	[11,15]	-8	hSpCas9	negative selection	1808474
184245542	184245565	3	-	26627737	HCT116	viability after 6 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.7594688574970299	[383]	[136,82]	4	hSpCas9	negative selection	1808475
184245722	184245745	3	-	26627737	HCT116	viability after 6 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	1.298023506157647	[428]	[364,55]	7	hSpCas9	negative selection	1808476
184248930	184248953	3	-	26627737	HCT116	viability after 6 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.24925628153383161	[632]	[310,11]	1	hSpCas9	negative selection	1808477
184249256	184249279	3	-	26627737	HCT116	viability after 6 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.06665985607901326	[398]	[182,0]	0	hSpCas9	negative selection	1808478
184243891	184243914	3	+	26627737	HCT116	viability after 8 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	1.1250428364596003	[123]	[196,106,143]	8	hSpCas9	negative selection	1890788
184245271	184245294	3	-	26627737	HCT116	viability after 8 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.0276783861024266	[476]	[141,115,128]	-8	hSpCas9	negative selection	1890789
184245542	184245565	3	-	26627737	HCT116	viability after 8 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.06565595873181296	[495]	[283,364,209]	0	hSpCas9	negative selection	1890790
184245722	184245745	3	-	26627737	HCT116	viability after 8 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.3167909604530113	[310]	[141,194,300]	3	hSpCas9	negative selection	1890791
184248930	184248953	3	-	26627737	HCT116	viability after 8 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	0.03983609495812908	[304]	[238,149,130]	0	hSpCas9	negative selection	1890792
184249256	184249279	3	-	26627737	HCT116	viability after 8 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	1.890880621865036	[60]	[115,65,190]	9	hSpCas9	negative selection	1890793
184243891	184243914	3	+	26627737	HCT116	viability after 9 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	1.1696261632632758	[272]	[187,144]	7	hSpCas9	negative selection	1973103
184245271	184245294	3	-	26627737	HCT116	viability after 9 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.1785141236259522	[358]	[15,138]	-1	hSpCas9	negative selection	1973104
184245542	184245565	3	-	26627737	HCT116	viability after 9 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.625493426393174	[383]	[412,239]	8	hSpCas9	negative selection	1973105
184245722	184245745	3	-	26627737	HCT116	viability after 9 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.7002229092157166	[428]	[370,39]	5	hSpCas9	negative selection	1973106
184248930	184248953	3	-	26627737	HCT116	viability after 9 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.11616964017097764	[632]	[351,0]	-1	hSpCas9	negative selection	1973107
184249256	184249279	3	-	26627737	HCT116	viability after 9 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.3115618849440793	[398]	[72,95]	-2	hSpCas9	negative selection	1973108
184243891	184243914	3	+	26627737	HCT116	viability after 12 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	0.9444559412013617	[123]	[78,112,187]	7	hSpCas9	negative selection	2055418
184245271	184245294	3	-	26627737	HCT116	viability after 12 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.5165862645068112	[476]	[169,127,226]	-5	hSpCas9	negative selection	2055419
184245542	184245565	3	-	26627737	HCT116	viability after 12 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.15058858279646015	[495]	[223,175,303]	-1	hSpCas9	negative selection	2055420
184245722	184245745	3	-	26627737	HCT116	viability after 12 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.6024349973198179	[310]	[189,266,292]	5	hSpCas9	negative selection	2055421
184248930	184248953	3	-	26627737	HCT116	viability after 12 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.3976593596005736	[304]	[244,72,34]	-4	hSpCas9	negative selection	2055422
184249256	184249279	3	-	26627737	HCT116	viability after 12 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	2.5218764012899313	[60]	[230,174,141]	9	hSpCas9	negative selection	2055423
184243891	184243914	3	+	26627737	HCT116	viability after 15 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	0.8207682103822174	[123]	[91,217,63]	7	hSpCas9	negative selection	2137733
184245271	184245294	3	-	26627737	HCT116	viability after 15 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.9299364916187621	[476]	[148,139,142]	-7	hSpCas9	negative selection	2137734
184245542	184245565	3	-	26627737	HCT116	viability after 15 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.11425971066167384	[495]	[407,209,189]	-1	hSpCas9	negative selection	2137735
184245722	184245745	3	-	26627737	HCT116	viability after 15 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.1347965602730808	[310]	[205,145,236]	1	hSpCas9	negative selection	2137736
184248930	184248953	3	-	26627737	HCT116	viability after 15 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.1971335946719775	[304]	[291,87,95]	-2	hSpCas9	negative selection	2137737
184249256	184249279	3	-	26627737	HCT116	viability after 15 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	2.141016241479466	[60]	[267,107,101]	9	hSpCas9	negative selection	2137738
184243891	184243914	3	+	26627737	HCT116	viability after 18 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	1.0628721386448912	[123]	[171,94,109]	8	hSpCas9	negative selection	2220048
184245271	184245294	3	-	26627737	HCT116	viability after 18 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.409042748145519	[476]	[59,67,135]	-8	hSpCas9	negative selection	2220049
184245542	184245565	3	-	26627737	HCT116	viability after 18 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.46769965765625654	[495]	[366,229,407]	4	hSpCas9	negative selection	2220050
184245722	184245745	3	-	26627737	HCT116	viability after 18 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.7235661643500707	[310]	[341,173,232]	6	hSpCas9	negative selection	2220051
184248930	184248953	3	-	26627737	HCT116	viability after 18 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.8016454611565481	[304]	[85,64,104]	-6	hSpCas9	negative selection	2220052
184249256	184249279	3	-	26627737	HCT116	viability after 18 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	2.1613034477161834	[60]	[103,106,188]	9	hSpCas9	negative selection	2220053
184249149	184249172	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCAGTTTATACCCAGCCCTGG	ALG3	ENSG00000214160	-2.442978634435476	[40,180]	[3,3]	-9	dCas9-VP64	positive selection	2438591
184249042	184249065	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAAGACTGGCTACTCGGATCGG	ALG3	ENSG00000214160	0.572193225927164	[43,57]	[26,4]	2	dCas9-VP64	positive selection	2438592
184249102	184249125	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAGCGTGGAGTGCATCAGAGG	ALG3	ENSG00000214160	0.679404751257144	[0,8]	[1,0]	3	dCas9-VP64	positive selection	2438593
184249516	184249539	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGATAGTTTTCCCAGCCGGAGG	ALG3	ENSG00000214160	1.0826613614195415	[86,33]	[19,34]	4	dCas9-VP64	positive selection	2459567
184249493	184249516	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCCGGAGGATTCAGGGTCTGG	ALG3	ENSG00000214160	-0.06497091856628723	[17,4]	[1,1]	0	dCas9-VP64	positive selection	2459568
184249465	184249488	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGGCCCTAGGAAATGACTTGG	ALG3	ENSG00000214160	-0.3326150744354538	[120,256]	[25,40]	-1	dCas9-VP64	positive selection	2459569
184249149	184249172	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCAGTTTATACCCAGCCCTGG	ALG3	ENSG00000214160	-0.18078141884298782	[131,73]	[28,29]	-2	dCas9-VP64	positive selection	2533846
184249042	184249065	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAAGACTGGCTACTCGGATCGG	ALG3	ENSG00000214160	-0.030004284621829025	[218,120]	[57,50]	0	dCas9-VP64	positive selection	2533847
184249102	184249125	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAGCGTGGAGTGCATCAGAGG	ALG3	ENSG00000214160	-1.2544297793511339	[32,94]	[7,7]	-9	dCas9-VP64	positive selection	2533848
184249516	184249539	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGATAGTTTTCCCAGCCGGAGG	ALG3	ENSG00000214160	-1.163363339856203	[394,92]	[47,23]	-9	dCas9-VP64	positive selection	2554822
184249493	184249516	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCCGGAGGATTCAGGGTCTGG	ALG3	ENSG00000214160	-1.999749238531218	[139,3]	[8,1]	-9	dCas9-VP64	positive selection	2554823
184249465	184249488	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGGCCCTAGGAAATGACTTGG	ALG3	ENSG00000214160	0.7499569669307053	[44,188]	[31,92]	5	dCas9-VP64	positive selection	2554824
184245777	184245800	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-0.5168539791747389	[3,4]	[4,0]	-6	hSpCas9	positive selection	2969914
184245487	184245510	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	-0.7893479154505963	[5,4]	[4,0]	-8	hSpCas9	positive selection	2969915
184245330	184245353	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	-1.3556257532807034	[1,2]	[0,0]	-9	hSpCas9	positive selection	2969916
184245731	184245754	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	-0.6568870079256849	[4,3]	[2,1]	-7	hSpCas9	positive selection	2969917
184245777	184245800	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-0.07284810385871086	[3,3]	[2,2]	-1	hSpCas9	positive selection	3037772
184245487	184245510	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	-0.4051805137608836	[5,5]	[3,1]	-6	hSpCas9	positive selection	3037773
184245330	184245353	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	0.8181487284025962	[1,1]	[4,0]	9	hSpCas9	positive selection	3037774
184245731	184245754	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	0.6558845723763527	[4,4]	[4,5]	9	hSpCas9	positive selection	3037775
184245760	184245783		+	24336571	A375	resistance to PLX after 7 days	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	-0.16655834033579087	[63,64]	[54,57]	-5	hSpCas9	positive selection	3113940
184245732	184245755		-	24336571	A375	resistance to PLX after 7 days	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.45010600181704885	[20,20]	[29,26]	9	hSpCas9	positive selection	3113951
184245467	184245490		-	24336571	A375	resistance to PLX after 7 days	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.6079140762612096	[15,17]	[25,25]	9	hSpCas9	positive selection	3113962
184245559	184245582		-	24336571	A375	resistance to PLX after 7 days	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.28557666299042195	[24,23]	[19,19]	-8	hSpCas9	positive selection	3113973
184245760	184245783		+	24336571	A375	resistance to PLX after 14 days	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	1.7680262403506248	[53,44]	[77,79]	9	hSpCas9	positive selection	3171733
184245732	184245755		-	24336571	A375	resistance to PLX after 14 days	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	4.503812634933768	[20,20]	[241,218]	9	hSpCas9	positive selection	3171744
184245467	184245490		-	24336571	A375	resistance to PLX after 14 days	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	6.090536784042872	[15,19]	[538,619]	9	hSpCas9	positive selection	3171755
184245559	184245582		-	24336571	A375	resistance to PLX after 14 days	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.23998734424209123	[21,31]	[10,17]	2	hSpCas9	positive selection	3171766
184245760	184245783		+	24336571	A375	viability after 7 days	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	0.3082407131657561	[53]	[63,64]	5	hSpCas9	negative selection	3229526
184245732	184245755		-	24336571	A375	viability after 7 days	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.49027529294739725	[30]	[20,20]	-6	hSpCas9	negative selection	3229537
184245467	184245490		-	24336571	A375	viability after 7 days	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.4781010897078363	[24]	[15,17]	-6	hSpCas9	negative selection	3229548
184245559	184245582		-	24336571	A375	viability after 7 days	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.3304407228579045	[19]	[24,23]	5	hSpCas9	negative selection	3229559
184245760	184245783		+	24336571	A375	viability after 14 days	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	-0.0450760956531413	[53]	[53,44]	0	hSpCas9	negative selection	3287319
184245732	184245755		-	24336571	A375	viability after 14 days	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4532005308982998	[30]	[20,20]	-5	hSpCas9	negative selection	3287330
184245467	184245490		-	24336571	A375	viability after 14 days	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.39772246982448517	[24]	[15,19]	-5	hSpCas9	negative selection	3287341
184245559	184245582		-	24336571	A375	viability after 14 days	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.467016537581011	[19]	[21,31]	6	hSpCas9	negative selection	3287352
184248808	184248831	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	1.5019149499588107	[56,50]	[0,0]	6	hSpCas9	positive selection	3336293
184248906	184248929	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	1.9901723391026378	[39,36]	[0,0]	7	hSpCas9	positive selection	3336294
184245770	184245793	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	1.7190802096317093	[41,50]	[0,0]	7	hSpCas9	positive selection	3336295
184245732	184245755	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-1.0187981938284023	[309,309]	[0,0]	-6	hSpCas9	positive selection	3355550
184245559	184245582	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3355551
184245467	184245490	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3355552
184245777	184245800	3	-	26780180	HT29	viability (Avana library 4 designs)	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	1.11959957786966	[]	[]	4	hSpCas9	negative selection	3405994
184245486	184245509	3	+	26780180	HT29	viability (Avana library 4 designs)	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	1.62514186392492	[]	[]	6	hSpCas9	negative selection	3405995
184245329	184245352	3	+	26780180	HT29	viability (Avana library 4 designs)	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	1.10884531077026	[]	[]	4	hSpCas9	negative selection	3405996
184245731	184245754	3	-	26780180	HT29	viability (Avana library 4 designs)	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	1.66319613415652	[]	[]	6	hSpCas9	negative selection	3405997
184245486	184245509	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	0.0107583863355607	[]	[]	0	hSpCas9	negative selection	3478286
184245329	184245352	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	-2.17501702631588	[]	[]	-3	hSpCas9	negative selection	3478287
184245777	184245800	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	5.7152743484619	[]	[]	9	hSpCas9	negative selection	3478288
184245731	184245754	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	-5.08498033194705	[]	[]	-5	hSpCas9	negative selection	3478289
184244660	184244683	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAAGAAACAGTAACCCAGGG	ALG3	ENSG00000214160	-4.29500496333862	[]	[]	-5	hSpCas9	negative selection	3478290
184244661	184244684	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAAGAAACAGTAACCCAGGGG	ALG3	ENSG00000214160	-1.79524752461405	[]	[]	-2	hSpCas9	negative selection	3478291
184245486	184245509	3	+	26780180	A375	viability (Avana lentiGuide)	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	-2.64361699199954	[]	[]	-5	hSpCas9	negative selection	3586945
184245329	184245352	3	+	26780180	A375	viability (Avana lentiGuide)	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	3.92207750979639	[]	[]	4	hSpCas9	negative selection	3586946
184245777	184245800	3	-	26780180	A375	viability (Avana lentiGuide)	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-1.3467638993429	[]	[]	-2	hSpCas9	negative selection	3586947
184245731	184245754	3	-	26780180	A375	viability (Avana lentiGuide)	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	-2.26883578749056	[]	[]	-4	hSpCas9	negative selection	3586948
184244660	184244683	3	+	26780180	A375	viability (Avana lentiGuide)	GGAGAAGAAACAGTAACCCAGGG	ALG3	ENSG00000214160	4.28986139331286	[]	[]	4	hSpCas9	negative selection	3586949
184244661	184244684	3	+	26780180	A375	viability (Avana lentiGuide)	GAGAAGAAACAGTAACCCAGGGG	ALG3	ENSG00000214160	1.32815193784909	[]	[]	1	hSpCas9	negative selection	3586950
184245486	184245509	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	-0.09585824682456515	[6]	[5,5]	-1	hSpCas9	positive selection	3695604
184245329	184245352	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	-0.10399571053634432	[4]	[3,4]	-2	hSpCas9	positive selection	3695605
184245777	184245800	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.24377008109647338	[5]	[6,5]	7	hSpCas9	positive selection	3695606
184245731	184245754	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	-0.5393971192174649	[6]	[4,3]	-7	hSpCas9	positive selection	3695607
184244660	184244683	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAAGAAACAGTAACCCAGGG	ALG3	ENSG00000214160	-0.17633066165866712	[5]	[5,4]	-3	hSpCas9	positive selection	3695608
184244661	184244684	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAAGAAACAGTAACCCAGGGG	ALG3	ENSG00000214160	-0.8616305900958378	[4]	[2,1]	-8	hSpCas9	positive selection	3695609
184245486	184245509	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCAAGAAGACAAGCAGCAAGG	ALG3	ENSG00000214160	0.10962601482290896	[6]	[5,6]	2	hSpCas9	positive selection	3804211
184245329	184245352	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACATGAAGAAAAAGACGAAGG	ALG3	ENSG00000214160	-0.9615621133514152	[4]	[1,0]	-8	hSpCas9	positive selection	3804212
184245777	184245800	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-0.6654810819019901	[6]	[2,2]	-7	hSpCas9	positive selection	3804213
184245731	184245754	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGACTATACCCAACTGCAGGG	ALG3	ENSG00000214160	0.26626675556121393	[5]	[5,5]	7	hSpCas9	positive selection	3804214
184244660	184244683	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAAGAAACAGTAACCCAGGG	ALG3	ENSG00000214160	-0.06268225855181037	[6]	[5,4]	-1	hSpCas9	positive selection	3804215
184244661	184244684	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAAGAAACAGTAACCCAGGGG	ALG3	ENSG00000214160	-0.469593876320501	[5]	[2,2]	-6	hSpCas9	positive selection	3804216
184245732	184245755	3	-	26780180	A375	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	1.15123575556479	[]	[]	6	hSpCas9	negative selection	3912618
184248906	184248929	3	-	26780180	A375	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	1.22297466665008	[]	[]	6	hSpCas9	negative selection	3912619
184245467	184245490	3	-	26780180	A375	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.990967801169914	[]	[]	4	hSpCas9	negative selection	3912620
184245770	184245793	3	-	26780180	A375	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	1.03635614378125	[]	[]	5	hSpCas9	negative selection	3912621
184248808	184248831	3	-	26780180	A375	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.713240326149884	[]	[]	2	hSpCas9	negative selection	3912622
184245559	184245582	3	-	26780180	A375	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	1.04884840136959	[]	[]	5	hSpCas9	negative selection	3912623
184245732	184245755	3	-	26780180	HT29	viability (GeCKOv2 library)	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	1.65014491073455	[]	[]	8	hSpCas9	negative selection	4020584
184248906	184248929	3	-	26780180	HT29	viability (GeCKOv2 library)	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	1.13761041349284	[]	[]	5	hSpCas9	negative selection	4020585
184245467	184245490	3	-	26780180	HT29	viability (GeCKOv2 library)	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	1.19320174181799	[]	[]	6	hSpCas9	negative selection	4020586
184245770	184245793	3	-	26780180	HT29	viability (GeCKOv2 library)	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	1.48995052467666	[]	[]	7	hSpCas9	negative selection	4020587
184248808	184248831	3	-	26780180	HT29	viability (GeCKOv2 library)	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	1.50605726508096	[]	[]	7	hSpCas9	negative selection	4020588
184245559	184245582	3	-	26780180	HT29	viability (GeCKOv2 library)	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	1.46488087017903	[]	[]	7	hSpCas9	negative selection	4020589
184245760	184245783	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	0.3239462913231044	[5]	[3,6]	7	hSpCas9	positive selection	4136928
184245732	184245755	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.7427260657012335	[4]	[2,7]	9	hSpCas9	positive selection	4136939
184245467	184245490	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.8677940185144521	[4]	[2,9]	9	hSpCas9	positive selection	4136950
184245559	184245582	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.19807210441500567	[4]	[3,3]	5	hSpCas9	positive selection	4136961
184245760	184245783	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGATGACGCCTTCTACCTCGG	ALG3	ENSG00000214160	1.0011123905515482	[5]	[6,4,4,4]	7	hSpCas9	positive selection	4200950
184245732	184245755	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.7515911565018762	[4]	[1,2,0,3]	5	hSpCas9	positive selection	4200961
184245467	184245490	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.6350369077929654	[4]	[0,5,1,3]	4	hSpCas9	positive selection	4200972
184245559	184245582	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	1.326815364918093	[3]	[4,3,1,4]	9	hSpCas9	positive selection	4200983
184248808	184248831	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.3412015696913826	[2]	[2,1]	7	hSpCas9	positive selection	4255331
184248906	184248929	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.020265866237173635	[2]	[1,0]	0	hSpCas9	positive selection	4255332
184245770	184245793	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.20562014671049222	[1]	[1,0]	-4	hSpCas9	positive selection	4255333
184245732	184245755	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.29382296726642937	[4]	[4,3]	6	hSpCas9	positive selection	4319613
184245559	184245582	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.011617147175456005	[3]	[3,1]	0	hSpCas9	positive selection	4319614
184245467	184245490	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.053309746658203316	[1]	[1,0]	-1	hSpCas9	positive selection	4319615
184245271	184245293	3	-	27760321	OCIAML3	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.41790428881702985	[458,376]	[471,385]	5	hSpCas9	negative selection	4377422
184245344	184245366	3	+	27760321	OCIAML3	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.5681819397296635	[84,83]	[45,42]	-5	hSpCas9	negative selection	4377423
184245559	184245581	3	-	27760321	OCIAML3	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.40900872262157884	[1003,933]	[894,1151]	5	hSpCas9	negative selection	4377424
184245591	184245613	3	+	27760321	OCIAML3	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-0.18029984377398806	[372,282]	[234,210]	-2	hSpCas9	negative selection	4377425
184245758	184245780	3	-	27760321	OCIAML3	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.6104475919904497	[212,184]	[167,326]	7	hSpCas9	negative selection	4377426
184245271	184245293	3	-	27760321	OCIAML2	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.19620229742227263	[458,376]	[303,492]	2	hSpCas9	negative selection	4460885
184245344	184245366	3	+	27760321	OCIAML2	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-1.8672873398533985	[84,83]	[7,32]	-9	hSpCas9	negative selection	4460886
184245559	184245581	3	-	27760321	OCIAML2	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.35166965128890704	[1003,933]	[852,1194]	5	hSpCas9	negative selection	4460887
184245591	184245613	3	+	27760321	OCIAML2	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-0.02777779073245301	[372,282]	[290,214]	0	hSpCas9	negative selection	4460888
184245758	184245780	3	-	27760321	OCIAML2	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	-0.32633025656569115	[212,184]	[137,114]	-4	hSpCas9	negative selection	4460889
184245271	184245293	3	-	27760321	MV411	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.2284172304118997	[458,376]	[444,940]	8	hSpCas9	negative selection	4544348
184245344	184245366	3	+	27760321	MV411	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	0.8505371990426374	[84,83]	[135,47]	6	hSpCas9	negative selection	4544349
184245559	184245581	3	-	27760321	MV411	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.5078018853648263	[1003,933]	[793,1082]	3	hSpCas9	negative selection	4544350
184245591	184245613	3	+	27760321	MV411	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	1.822637386196281	[372,282]	[910,531]	9	hSpCas9	negative selection	4544351
184245758	184245780	3	-	27760321	MV411	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.9688280351480973	[212,184]	[239,280]	7	hSpCas9	negative selection	4544352
184245271	184245293	3	-	27760321	HL60	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.46728275174543904	[458,376]	[446,493]	5	hSpCas9	negative selection	4627811
184245344	184245366	3	+	27760321	HL60	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.4324156032342854	[84,83]	[60,40]	-5	hSpCas9	negative selection	4627812
184245559	184245581	3	-	27760321	HL60	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.5487953390366627	[1003,933]	[1184,1129]	6	hSpCas9	negative selection	4627813
184245591	184245613	3	+	27760321	HL60	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	0.5619534779717239	[372,282]	[338,448]	6	hSpCas9	negative selection	4627814
184245758	184245780	3	-	27760321	HL60	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.7124976968087591	[212,184]	[338,187]	7	hSpCas9	negative selection	4627815
184245271	184245293	3	-	27760321	HT1080	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.5548892266676875	[376,293]	[332,457]	8	hSpCas9	negative selection	4711274
184245344	184245366	3	+	27760321	HT1080	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	0.8529145931986961	[83,65]	[0,111]	4	hSpCas9	negative selection	4711275
184245559	184245581	3	-	27760321	HT1080	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.6442899928624073	[933,728]	[511,523]	3	hSpCas9	negative selection	4711276
184245591	184245613	3	+	27760321	HT1080	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-4.120063974544451	[282,220]	[0,10]	-8	hSpCas9	negative selection	4711277
184245758	184245780	3	-	27760321	HT1080	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.32673705124332486	[184,144]	[49,117]	1	hSpCas9	negative selection	4711278
184245271	184245293	3	-	27760321	HT29	viability after 7 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.20785316101658058	[376,293]	[595,452,459]	3	hSpCas9	negative selection	4794737
184245344	184245366	3	+	27760321	HT29	viability after 7 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	0.6260877026075897	[83,65]	[106,105,224]	8	hSpCas9	negative selection	4794738
184245559	184245581	3	-	27760321	HT29	viability after 7 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.4527703376441299	[933,728]	[1439,1792,1160]	7	hSpCas9	negative selection	4794739
184245591	184245613	3	+	27760321	HT29	viability after 7 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	0.05012614467500259	[282,220]	[642,205,204]	0	hSpCas9	negative selection	4794740
184245758	184245780	3	-	27760321	HT29	viability after 7 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	-0.013259248574883475	[184,144]	[126,325,166]	0	hSpCas9	negative selection	4794741
184245271	184245293	3	-	27760321	HT29	viability after 25 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.22539325893971762	[376,293]	[313,481,171]	-2	hSpCas9	negative selection	4878200
184245344	184245366	3	+	27760321	HT29	viability after 25 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.6248571836522583	[83,65]	[10,98,59]	-5	hSpCas9	negative selection	4878201
184245559	184245581	3	-	27760321	HT29	viability after 25 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.12998949659598336	[933,728]	[1187,1101,792]	1	hSpCas9	negative selection	4878202
184245591	184245613	3	+	27760321	HT29	viability after 25 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-1.007934256176962	[282,220]	[103,131,201]	-6	hSpCas9	negative selection	4878203
184245758	184245780	3	-	27760321	HT29	viability after 25 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	-0.395338552160287	[184,144]	[196,82,146]	-4	hSpCas9	negative selection	4878204
184245271	184245293	3	-	27760321	HT29	viability after 22 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.2790618242950826	[376,293]	[758,486,154]	3	hSpCas9	negative selection	4961663
184245344	184245366	3	+	27760321	HT29	viability after 22 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.8129015503519956	[83,65]	[110,33,0]	-6	hSpCas9	negative selection	4961664
184245559	184245581	3	-	27760321	HT29	viability after 22 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.3336416688870434	[933,728]	[1251,1269,1109]	3	hSpCas9	negative selection	4961665
184245591	184245613	3	+	27760321	HT29	viability after 22 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-0.8926691785860189	[282,220]	[148,160,160]	-6	hSpCas9	negative selection	4961666
184245758	184245780	3	-	27760321	HT29	viability after 22 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	-0.6186823507031336	[184,144]	[50,173,149]	-5	hSpCas9	negative selection	4961667
184245271	184245293	3	-	27760321	HT29	viability after 19 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.19595379609530955	[376,293]	[323,860,132]	1	hSpCas9	negative selection	5045126
184245344	184245366	3	+	27760321	HT29	viability after 19 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-1.1387378666503158	[83,65]	[68,37,13]	-7	hSpCas9	negative selection	5045127
184245559	184245581	3	-	27760321	HT29	viability after 19 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.09016897157624126	[933,728]	[1202,1237,629]	0	hSpCas9	negative selection	5045128
184245591	184245613	3	+	27760321	HT29	viability after 19 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-0.4502853101580794	[282,220]	[127,391,107]	-4	hSpCas9	negative selection	5045129
184245758	184245780	3	-	27760321	HT29	viability after 19 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.5346697254510243	[184,144]	[29,232,521]	5	hSpCas9	negative selection	5045130
184245271	184245293	3	-	27760321	HT29	viability after 16 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.17768070129726427	[376,293]	[469,417,389]	2	hSpCas9	negative selection	5128589
184245344	184245366	3	+	27760321	HT29	viability after 16 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.36839536833615183	[83,65]	[42,102,45]	-4	hSpCas9	negative selection	5128590
184245559	184245581	3	-	27760321	HT29	viability after 16 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.2862062402929839	[933,728]	[1336,1525,548]	3	hSpCas9	negative selection	5128591
184245591	184245613	3	+	27760321	HT29	viability after 16 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	-0.35577451951769046	[282,220]	[269,244,149]	-4	hSpCas9	negative selection	5128592
184245758	184245780	3	-	27760321	HT29	viability after 16 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	-0.4243092076760089	[184,144]	[220,47,153]	-4	hSpCas9	negative selection	5128593
184245271	184245293	3	-	27760321	HT29	viability after 13 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.20847673013586915	[376,293]	[423,507,418]	2	hSpCas9	negative selection	5212052
184245344	184245366	3	+	27760321	HT29	viability after 13 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-0.5467641273613095	[83,65]	[22,64,88]	-6	hSpCas9	negative selection	5212053
184245559	184245581	3	-	27760321	HT29	viability after 13 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.45857431354811884	[933,728]	[1615,1241,1129]	6	hSpCas9	negative selection	5212054
184245591	184245613	3	+	27760321	HT29	viability after 13 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	0.45777457797883037	[282,220]	[465,466,278]	6	hSpCas9	negative selection	5212055
184245758	184245780	3	-	27760321	HT29	viability after 13 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.014354995426775652	[184,144]	[171,194,211]	0	hSpCas9	negative selection	5212056
184245271	184245293	3	-	27760321	HT29	viability after 10 days	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.8996682496696866	[376,293]	[941,844,563]	9	hSpCas9	negative selection	5295515
184245344	184245366	3	+	27760321	HT29	viability after 10 days	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	0.25696262753349597	[83,65]	[85,6,236]	3	hSpCas9	negative selection	5295516
184245559	184245581	3	-	27760321	HT29	viability after 10 days	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.45553603826561373	[933,728]	[1780,1369,1124]	6	hSpCas9	negative selection	5295517
184245591	184245613	3	+	27760321	HT29	viability after 10 days	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	0.5916804206979297	[282,220]	[396,579,448]	7	hSpCas9	negative selection	5295518
184245758	184245780	3	-	27760321	HT29	viability after 10 days	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.5010389539082268	[184,144]	[220,165,479]	6	hSpCas9	negative selection	5295519
184245271	184245293	3	-	27760321	MOLM13	viability	CGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.8502366400391862	[458,376]	[649,229]	6	hSpCas9	negative selection	5378978
184245344	184245366	3	+	27760321	MOLM13	viability	GACGAAGGGAGGTACCTAAAGG	ALG3	ENSG00000214160	-1.7576128042717474	[84,83]	[18,9]	-7	hSpCas9	negative selection	5378979
184245559	184245581	3	-	27760321	MOLM13	viability	TGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.0649756741502292	[1003,933]	[807,279]	0	hSpCas9	negative selection	5378980
184245591	184245613	3	+	27760321	MOLM13	viability	GATGTACACGAAACCAGCTGGG	ALG3	ENSG00000214160	1.5439517196293135	[372,282]	[658,429]	9	hSpCas9	negative selection	5378981
184245758	184245780	3	-	27760321	MOLM13	viability	AGGTAGAAGGCGTCATCAATGG	ALG3	ENSG00000214160	0.9685934978729089	[212,184]	[263,180]	7	hSpCas9	negative selection	5378982
184248521	184248544	3	+	27661255	K562	viability	GTGCAGAAGGCCAATCTCTAGGG	ALG3	ENSG00000214160	0.15414264224277918	[1200,1305]	[1179,1054]	5	dCas9-KRAB	negative selection	5461828
184248531	184248554	3	-	27661255	K562	viability	GAGGTGGATACCCTAGAGATTGG	ALG3	ENSG00000214160	-0.007389099755137574	[1520,1583]	[1247,1219]	0	dCas9-KRAB	negative selection	5461829
184248915	184248938	3	-	27661255	K562	viability	GCGGCTGGGCTGCGGAAACGCGG	ALG3	ENSG00000214160	0.46286944389616225	[251,300]	[337,273]	9	dCas9-KRAB	negative selection	5461830
184248934	184248957	3	-	27661255	K562	viability	GCGGCGCACCGTTAAGATGGCGG	ALG3	ENSG00000214160	0.0016904417013497743	[685,823]	[671,541]	0	dCas9-KRAB	negative selection	5461831
184248953	184248976	3	-	27661255	K562	viability	GGGTGGTGGGCCCACACAAGCGG	ALG3	ENSG00000214160	0.49177931272287373	[393,484]	[527,460]	9	dCas9-KRAB	negative selection	5461832
184249532	184249555	3	-	27661255	K562	viability	GCGCTCTTCGAAGAATCCTCCGG	ALG3	ENSG00000214160	-1.1896758556162874	[10,20]	[4,5]	-8	dCas9-KRAB	negative selection	5461833
184248808	184248831	3	-	27260156	BXPC3	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.15961510125770983	[206]	[134,283,178,173]	-4	hSpCas9	negative selection	5527791
184248906	184248929	3	-	27260156	BXPC3	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.2390899188569856	[201]	[297,281,167,236]	5	hSpCas9	negative selection	5527792
184245770	184245793	3	-	27260156	BXPC3	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.18191603896085562	[138]	[77,106,154,185]	-4	hSpCas9	negative selection	5527793
184245732	184245755	3	-	27260156	BXPC3	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4208679428676283	[1255]	[905,1065,930,1020]	-7	hSpCas9	negative selection	5592073
184245559	184245582	3	-	27260156	BXPC3	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.23953937189979152	[707]	[562,582,579,808]	-5	hSpCas9	negative selection	5592074
184245467	184245490	3	-	27260156	BXPC3	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.040829694529730176	[174]	[178,106,149,291]	-1	hSpCas9	negative selection	5592075
184248808	184248831	3	-	27260156	A673	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.28067772981860806	[206]	[332,241,129,122]	-6	hSpCas9	negative selection	5649042
184248906	184248929	3	-	27260156	A673	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.15788112184389713	[201]	[329,256,266,232]	4	hSpCas9	negative selection	5649043
184245770	184245793	3	-	27260156	A673	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.3406225881023206	[138]	[148,91,123,166]	-7	hSpCas9	negative selection	5649044
184245732	184245755	3	-	27260156	A673	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4405397201089769	[1255]	[1237,925,1078,1225]	-8	hSpCas9	negative selection	5713324
184245559	184245582	3	-	27260156	A673	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.10678883279970558	[707]	[902,546,896,829]	-3	hSpCas9	negative selection	5713325
184245467	184245490	3	-	27260156	A673	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.23408898518217613	[174]	[201,149,166,199]	-5	hSpCas9	negative selection	5713326
184248808	184248831	3	-	27260156	A375	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.20505171509234155	[206]	[289,405,179,257]	3	hSpCas9	negative selection	5770293
184248906	184248929	3	-	27260156	A375	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.2789550796776449	[201]	[253,336,321,242]	4	hSpCas9	negative selection	5770294
184245770	184245793	3	-	27260156	A375	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.11772812165181534	[138]	[104,246,154,202]	1	hSpCas9	negative selection	5770295
184245732	184245755	3	-	27260156	A375	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4650584398005245	[1255]	[1351,930,841,1100]	-6	hSpCas9	negative selection	5834575
184245559	184245582	3	-	27260156	A375	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.03832601691733295	[707]	[755,872,783,812]	0	hSpCas9	negative selection	5834576
184245467	184245490	3	-	27260156	A375	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.26156029193887176	[174]	[303,157,134,92]	-4	hSpCas9	negative selection	5834577
184248808	184248831	3	-	27260156	COLO741	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.07545653994375101	[206]	[158,322,261]	-2	hSpCas9	negative selection	5891544
184248906	184248929	3	-	27260156	COLO741	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.608139112437474	[201]	[536,368,292]	9	hSpCas9	negative selection	5891545
184245770	184245793	3	-	27260156	COLO741	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.08561274464065294	[138]	[261,133,175]	1	hSpCas9	negative selection	5891546
184245732	184245755	3	-	27260156	COLO741	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.18613525254671992	[1255]	[1441,1655,1152]	-4	hSpCas9	negative selection	5955826
184245559	184245582	3	-	27260156	COLO741	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.14306752727655236	[707]	[823,865,769]	-3	hSpCas9	negative selection	5955827
184245467	184245490	3	-	27260156	COLO741	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.10760870341613993	[174]	[259,211,250]	2	hSpCas9	negative selection	5955828
184248808	184248831	3	-	27260156	CAL120	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.4157036628691213	[206]	[233,192,158]	-6	hSpCas9	negative selection	6012795
184248906	184248929	3	-	27260156	CAL120	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.8190941591258352	[201]	[640,387,332]	9	hSpCas9	negative selection	6012796
184245770	184245793	3	-	27260156	CAL120	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.2092443409137832	[138]	[297,72,100]	-3	hSpCas9	negative selection	6012797
184245732	184245755	3	-	27260156	CAL120	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-1.0079297758095014	[1255]	[909,650,789]	-8	hSpCas9	negative selection	6077077
184245559	184245582	3	-	27260156	CAL120	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.5011644679032582	[707]	[788,523,579]	-6	hSpCas9	negative selection	6077078
184245467	184245490	3	-	27260156	CAL120	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.44556913062548964	[174]	[139,195,140]	-6	hSpCas9	negative selection	6077079
184248808	184248831	3	-	27260156	CADOES1	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.2749554428831198	[206]	[142,149,170,172]	-5	hSpCas9	negative selection	6134046
184248906	184248929	3	-	27260156	CADOES1	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.1413410254037395	[201]	[303,174,206,139]	2	hSpCas9	negative selection	6134047
184245770	184245793	3	-	27260156	CADOES1	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.11905387509812138	[138]	[77,118,139,227]	2	hSpCas9	negative selection	6134048
184245732	184245755	3	-	27260156	CADOES1	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.19296779186500612	[1255]	[937,1039,905,1210]	-3	hSpCas9	negative selection	6198328
184245559	184245582	3	-	27260156	CADOES1	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.44624264683751946	[707]	[675,398,234,627]	-7	hSpCas9	negative selection	6198329
184245467	184245490	3	-	27260156	CADOES1	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.003076241353599851	[174]	[200,129,113,208]	0	hSpCas9	negative selection	6198330
184248808	184248831	3	-	27260156	EWS502	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.46547634619365486	[206]	[206,144,192,78]	-7	hSpCas9	negative selection	6255297
184248906	184248929	3	-	27260156	EWS502	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.13436921370261	[201]	[235,143,236,331]	2	hSpCas9	negative selection	6255298
184245770	184245793	3	-	27260156	EWS502	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.20754971678369705	[138]	[101,231,152,199]	3	hSpCas9	negative selection	6255299
184245732	184245755	3	-	27260156	EWS502	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.5812387010741135	[1255]	[692,1018,873,992]	-7	hSpCas9	negative selection	6319579
184245559	184245582	3	-	27260156	EWS502	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.18111075239575852	[707]	[603,619,691,741]	-3	hSpCas9	negative selection	6319580
184245467	184245490	3	-	27260156	EWS502	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.09709588919291723	[174]	[140,181,190,182]	-2	hSpCas9	negative selection	6319581
184248808	184248831	3	-	27260156	EW8	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.21707044853567004	[206]	[54,143,160,203]	-4	hSpCas9	negative selection	6376548
184248906	184248929	3	-	27260156	EW8	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.03270848289515316	[201]	[168,178,152,140]	0	hSpCas9	negative selection	6376549
184245770	184245793	3	-	27260156	EW8	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.24080746018056942	[138]	[130,89,141,166]	4	hSpCas9	negative selection	6376550
184245732	184245755	3	-	27260156	EW8	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.43589039381504147	[1255]	[847,1098,482,635]	-7	hSpCas9	negative selection	6440830
184245559	184245582	3	-	27260156	EW8	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.023568216311622203	[707]	[455,552,347,922]	0	hSpCas9	negative selection	6440831
184245467	184245490	3	-	27260156	EW8	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.20234210901835747	[174]	[121,256,104,173]	3	hSpCas9	negative selection	6440832
184248808	184248831	3	-	27260156	CORL105	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.7523659463395942	[206]	[109,146,149,167]	-8	hSpCas9	negative selection	6497799
184248906	184248929	3	-	27260156	CORL105	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.744655715578978	[201]	[270,322,482,517]	9	hSpCas9	negative selection	6497800
184245770	184245793	3	-	27260156	CORL105	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.3945394441449841	[138]	[125,156,106,101]	-6	hSpCas9	negative selection	6497801
184245732	184245755	3	-	27260156	CORL105	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.7330442003016785	[1255]	[711,755,1124,978]	-8	hSpCas9	negative selection	6562081
184245559	184245582	3	-	27260156	CORL105	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.23363094399941697	[707]	[883,514,846,605]	-4	hSpCas9	negative selection	6562082
184245467	184245490	3	-	27260156	CORL105	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.7244728426976461	[174]	[121,118,186,77]	-8	hSpCas9	negative selection	6562083
184248808	184248831	3	-	27260156	HS294T	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.2945661591196175	[206]	[45,99,174,71]	4	hSpCas9	negative selection	6619050
184248906	184248929	3	-	27260156	HS294T	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.07230852727918391	[201]	[57,81,79,78]	-1	hSpCas9	negative selection	6619051
184245770	184245793	3	-	27260156	HS294T	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.4650410755715242	[138]	[59,35,21,34]	-6	hSpCas9	negative selection	6619052
184245732	184245755	3	-	27260156	HS294T	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.5790706376937096	[1255]	[317,302,332,350]	-7	hSpCas9	negative selection	6683332
184245559	184245582	3	-	27260156	HS294T	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.24019356390367852	[707]	[243,215,266,191]	-3	hSpCas9	negative selection	6683333
184245467	184245490	3	-	27260156	HS294T	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.0564327136549172	[174]	[97,73,57,43]	0	hSpCas9	negative selection	6683334
184248808	184248831	3	-	27260156	HCC44	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.010185574521782925	[206]	[227,217,224,268]	0	hSpCas9	negative selection	6740301
184248906	184248929	3	-	27260156	HCC44	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.7232875095130253	[201]	[371,373,615,190]	9	hSpCas9	negative selection	6740302
184245770	184245793	3	-	27260156	HCC44	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.154560703960392	[138]	[87,183,161,122]	-3	hSpCas9	negative selection	6740303
184245732	184245755	3	-	27260156	HCC44	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.928981255722639	[1255]	[855,553,1061,602]	-8	hSpCas9	negative selection	6804583
184245559	184245582	3	-	27260156	HCC44	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.3830530093114841	[707]	[715,627,618,499]	-5	hSpCas9	negative selection	6804584
184245467	184245490	3	-	27260156	HCC44	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.16146164839211274	[174]	[70,201,186,232]	-3	hSpCas9	negative selection	6804585
184248808	184248831	3	-	27260156	G402	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-1.1056142823741355	[206]	[136,136,59,137]	-8	hSpCas9	negative selection	6861552
184248906	184248929	3	-	27260156	G402	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.5304099866050187	[201]	[273,562,254,331]	6	hSpCas9	negative selection	6861553
184245770	184245793	3	-	27260156	G402	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.1195228004289639	[138]	[181,121,151,168]	-1	hSpCas9	negative selection	6861554
184245732	184245755	3	-	27260156	G402	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.7742350811373452	[1255]	[1029,1081,898,613]	-7	hSpCas9	negative selection	6925834
184245559	184245582	3	-	27260156	G402	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.19237830543677292	[707]	[1043,552,611,837]	-2	hSpCas9	negative selection	6925835
184245467	184245490	3	-	27260156	G402	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.7498682381614656	[174]	[168,57,123,156]	-7	hSpCas9	negative selection	6925836
184248808	184248831	3	-	27260156	L33	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.11317361850342667	[206]	[193,116,110,109]	-3	hSpCas9	negative selection	6982803
184248906	184248929	3	-	27260156	L33	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.18888073289917395	[201]	[177,72,238,186]	4	hSpCas9	negative selection	6982804
184245770	184245793	3	-	27260156	L33	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.13326281180014843	[138]	[110,75,66,206]	3	hSpCas9	negative selection	6982805
184245732	184245755	3	-	27260156	L33	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.44265475780345687	[1255]	[815,338,572,1141]	-8	hSpCas9	negative selection	7047085
184245559	184245582	3	-	27260156	L33	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.25173748543344093	[707]	[610,262,399,489]	-5	hSpCas9	negative selection	7047086
184245467	184245490	3	-	27260156	L33	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.03112644270544762	[174]	[200,67,91,200]	0	hSpCas9	negative selection	7047087
184248808	184248831	3	-	27260156	K562	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.07714546480824014	[206]	[92,257,266,85]	-1	hSpCas9	negative selection	7104054
184248906	184248929	3	-	27260156	K562	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.09639302207689582	[201]	[137,273,79,264]	1	hSpCas9	negative selection	7104055
184245770	184245793	3	-	27260156	K562	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.8024593006470628	[138]	[45,67,34,124]	-7	hSpCas9	negative selection	7104056
184245732	184245755	3	-	27260156	K562	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-1.1181262499371767	[1255]	[543,672,410,442]	-8	hSpCas9	negative selection	7168336
184245559	184245582	3	-	27260156	K562	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.36030058793857006	[707]	[548,525,666,248]	-4	hSpCas9	negative selection	7168337
184245467	184245490	3	-	27260156	K562	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.16901515010047374	[174]	[106,90,194,281]	2	hSpCas9	negative selection	7168338
184248808	184248831	3	-	27260156	HT29	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.0411164599904712	[206]	[272,369,169,183]	-1	hSpCas9	negative selection	7225305
184248906	184248929	3	-	27260156	HT29	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.18768983941707318	[201]	[271,363,231,257]	3	hSpCas9	negative selection	7225306
184245770	184245793	3	-	27260156	HT29	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.10757888179905262	[138]	[182,222,218,113]	2	hSpCas9	negative selection	7225307
184245732	184245755	3	-	27260156	HT29	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.2740191490795767	[1255]	[1398,1440,1248,1009]	-5	hSpCas9	negative selection	7289587
184245559	184245582	3	-	27260156	HT29	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.02049288964829643	[707]	[839,903,745,895]	0	hSpCas9	negative selection	7289588
184245467	184245490	3	-	27260156	HT29	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.014733082870428404	[174]	[348,126,251,141]	0	hSpCas9	negative selection	7289589
184248808	184248831	3	-	27260156	MHHES1	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.36946052240094307	[206]	[164,224,128,196]	-6	hSpCas9	negative selection	7346556
184248906	184248929	3	-	27260156	MHHES1	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.1369027680888819	[201]	[266,250,234,244]	2	hSpCas9	negative selection	7346557
184245770	184245793	3	-	27260156	MHHES1	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.516161985923046	[138]	[101,176,133,43]	-7	hSpCas9	negative selection	7346558
184245732	184245755	3	-	27260156	MHHES1	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4829549191907917	[1255]	[1309,942,946,883]	-7	hSpCas9	negative selection	7410838
184245559	184245582	3	-	27260156	MHHES1	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.509090251886181	[707]	[768,623,536,373]	-7	hSpCas9	negative selection	7410839
184245467	184245490	3	-	27260156	MHHES1	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.740123939914543	[174]	[80,76,113,174]	-8	hSpCas9	negative selection	7410840
184248808	184248831	3	-	27260156	MEWO	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.09875507048655385	[206]	[213,165,168]	-2	hSpCas9	negative selection	7467807
184248906	184248929	3	-	27260156	MEWO	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.0623207511222883	[201]	[272,132,154]	-1	hSpCas9	negative selection	7467808
184245770	184245793	3	-	27260156	MEWO	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.3456747810192675	[138]	[168,81,68]	-6	hSpCas9	negative selection	7467809
184245732	184245755	3	-	27260156	MEWO	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.32614803113703195	[1255]	[982,1052,783]	-6	hSpCas9	negative selection	7532089
184245559	184245582	3	-	27260156	MEWO	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.09055623672316171	[707]	[671,574,628]	-2	hSpCas9	negative selection	7532090
184245467	184245490	3	-	27260156	MEWO	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.10899699531755114	[174]	[272,125,79]	-2	hSpCas9	negative selection	7532091
184248808	184248831	3	-	27260156	LNCAPCLONEFGC	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.3732667584094065	[206]	[123,131,203,128]	-5	hSpCas9	negative selection	7589058
184248906	184248929	3	-	27260156	LNCAPCLONEFGC	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.4978172640822387	[201]	[221,247,259,304]	7	hSpCas9	negative selection	7589059
184245770	184245793	3	-	27260156	LNCAPCLONEFGC	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.1247771590878064	[138]	[212,126,121,83]	2	hSpCas9	negative selection	7589060
184245732	184245755	3	-	27260156	LNCAPCLONEFGC	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.2602036435636903	[1255]	[918,869,1170,877]	-4	hSpCas9	negative selection	7653340
184245559	184245582	3	-	27260156	LNCAPCLONEFGC	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.48485747678229674	[707]	[349,369,661,488]	-6	hSpCas9	negative selection	7653341
184245467	184245490	3	-	27260156	LNCAPCLONEFGC	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.19178965720072805	[174]	[153,117,157,128]	-3	hSpCas9	negative selection	7653342
184248808	184248831	3	-	27260156	PANC0327	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-1.22619158752946	[206]	[70,45,109,90]	-9	hSpCas9	negative selection	7710309
184248906	184248929	3	-	27260156	PANC0327	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.06860979641473675	[201]	[168,149,212,154]	-1	hSpCas9	negative selection	7710310
184245770	184245793	3	-	27260156	PANC0327	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-1.1277994006324044	[138]	[45,103,41,26]	-8	hSpCas9	negative selection	7710311
184245732	184245755	3	-	27260156	PANC0327	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.7536732818589665	[1255]	[641,559,614,840]	-8	hSpCas9	negative selection	7774591
184245559	184245582	3	-	27260156	PANC0327	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.17314091048232244	[707]	[419,673,674,435]	-3	hSpCas9	negative selection	7774592
184245467	184245490	3	-	27260156	PANC0327	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-1.1353158815120044	[174]	[104,61,68,50]	-8	hSpCas9	negative selection	7774593
184248808	184248831	3	-	27260156	NCIH2009	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.30102894876639485	[206]	[362,189,176]	-4	hSpCas9	negative selection	7831560
184248906	184248929	3	-	27260156	NCIH2009	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.5033114139323132	[201]	[566,369,295]	7	hSpCas9	negative selection	7831561
184245770	184245793	3	-	27260156	NCIH2009	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.46709745226321053	[138]	[186,108,134]	-6	hSpCas9	negative selection	7831562
184245732	184245755	3	-	27260156	NCIH2009	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.7280374127661726	[1255]	[1368,821,1050]	-7	hSpCas9	negative selection	7895842
184245559	184245582	3	-	27260156	NCIH2009	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.04313407576737016	[707]	[1262,926,748]	0	hSpCas9	negative selection	7895843
184245467	184245490	3	-	27260156	NCIH2009	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.4844515623645633	[174]	[259,220,58]	-6	hSpCas9	negative selection	7895844
184248808	184248831	3	-	27260156	NCIH1373	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.48189127858531644	[206]	[271,69,194,39]	-5	hSpCas9	negative selection	7952811
184248906	184248929	3	-	27260156	NCIH1373	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.6528205631080123	[201]	[513,232,309,106]	6	hSpCas9	negative selection	7952812
184245770	184245793	3	-	27260156	NCIH1373	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.46707367602742167	[138]	[200,87,306,72]	4	hSpCas9	negative selection	7952813
184245732	184245755	3	-	27260156	NCIH1373	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.5783937057287803	[1255]	[737,785,1097,298]	-5	hSpCas9	negative selection	8017093
184245559	184245582	3	-	27260156	NCIH1373	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.4350424479619242	[707]	[703,505,484,179]	-4	hSpCas9	negative selection	8017094
184245467	184245490	3	-	27260156	NCIH1373	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.48275964446816744	[174]	[555,255,90,62]	5	hSpCas9	negative selection	8017095
184248808	184248831	3	-	27260156	PATU8902	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.5911932896700622	[206]	[210,341,67,172]	-5	hSpCas9	negative selection	8074062
184248906	184248929	3	-	27260156	PATU8902	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.3899629690842936	[201]	[500,477,309,172]	4	hSpCas9	negative selection	8074063
184245770	184245793	3	-	27260156	PATU8902	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.30071422192489994	[138]	[129,166,315,330]	3	hSpCas9	negative selection	8074064
184245732	184245755	3	-	27260156	PATU8902	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.9795502741588467	[1255]	[636,1165,840,916]	-7	hSpCas9	negative selection	8138344
184245559	184245582	3	-	27260156	PATU8902	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.20442259062245377	[707]	[1210,584,865,730]	-2	hSpCas9	negative selection	8138345
184245467	184245490	3	-	27260156	PATU8902	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.30186988537615433	[174]	[264,197,136,204]	-3	hSpCas9	negative selection	8138346
184248808	184248831	3	-	27260156	PANC1	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.28537655580359234	[206]	[271,309,147,159]	4	hSpCas9	negative selection	8195313
184248906	184248929	3	-	27260156	PANC1	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.45234788856086416	[201]	[237,169,285,237]	7	hSpCas9	negative selection	8195314
184245770	184245793	3	-	27260156	PANC1	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.501469239274493	[138]	[84,107,65,81]	-6	hSpCas9	negative selection	8195315
184245732	184245755	3	-	27260156	PANC1	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.6078433346736776	[1255]	[615,925,756,587]	-7	hSpCas9	negative selection	8259595
184245559	184245582	3	-	27260156	PANC1	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.2976522113954099	[707]	[449,583,416,531]	-5	hSpCas9	negative selection	8259596
184245467	184245490	3	-	27260156	PANC1	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.1868943004475616	[174]	[76,107,153,175]	-3	hSpCas9	negative selection	8259597
184248808	184248831	3	-	27260156	PANC0813	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.5907695599165439	[206]	[131,144,186,177]	-7	hSpCas9	negative selection	8316564
184248906	184248929	3	-	27260156	PANC0813	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.3601897974094721	[201]	[377,301,286,259]	6	hSpCas9	negative selection	8316565
184245770	184245793	3	-	27260156	PANC0813	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.15847766251069406	[138]	[143,84,197,291]	2	hSpCas9	negative selection	8316566
184245732	184245755	3	-	27260156	PANC0813	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.7306984724986092	[1255]	[1033,737,986,813]	-8	hSpCas9	negative selection	8380846
184245559	184245582	3	-	27260156	PANC0813	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.14937054189220045	[707]	[700,779,716,792]	-2	hSpCas9	negative selection	8380847
184245467	184245490	3	-	27260156	PANC0813	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.47752205593495756	[174]	[186,215,138,56]	-6	hSpCas9	negative selection	8380848
184248808	184248831	3	-	27260156	RDES	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.24143016674537576	[206]	[277,257,271,315]	4	hSpCas9	negative selection	8437815
184248906	184248929	3	-	27260156	RDES	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.555053607527762	[201]	[284,303,322,478]	8	hSpCas9	negative selection	8437816
184245770	184245793	3	-	27260156	RDES	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.47932093343036364	[138]	[176,155,205,386]	7	hSpCas9	negative selection	8437817
184245732	184245755	3	-	27260156	RDES	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.1103836804549172	[1255]	[1201,1260,1389,1522]	-2	hSpCas9	negative selection	8502097
184245559	184245582	3	-	27260156	RDES	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.010546043599475974	[707]	[875,716,778,827]	0	hSpCas9	negative selection	8502098
184245467	184245490	3	-	27260156	RDES	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.1849084100645242	[174]	[212,142,308,262]	3	hSpCas9	negative selection	8502099
184248808	184248831	3	-	27260156	PC3	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.34223694621134815	[206]	[124,181,292,94]	-7	hSpCas9	negative selection	8559066
184248906	184248929	3	-	27260156	PC3	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.002604695761361242	[201]	[154,74,600,133]	0	hSpCas9	negative selection	8559067
184245770	184245793	3	-	27260156	PC3	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.3262832080574707	[138]	[87,57,274,83]	-6	hSpCas9	negative selection	8559068
184245732	184245755	3	-	27260156	PC3	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.2093470609457957	[1255]	[726,794,2109,1165]	-5	hSpCas9	negative selection	8623348
184245559	184245582	3	-	27260156	PC3	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.14900578261240122	[707]	[441,589,1092,617]	-3	hSpCas9	negative selection	8623349
184245467	184245490	3	-	27260156	PC3	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.061698375906977576	[174]	[134,125,299,154]	-1	hSpCas9	negative selection	8623350
184248808	184248831	3	-	27260156	PATU8988T	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.11064178867443131	[206]	[102,267,141,368]	2	hSpCas9	negative selection	8680317
184248906	184248929	3	-	27260156	PATU8988T	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.20516034288790785	[201]	[131,264,280,224]	3	hSpCas9	negative selection	8680318
184245770	184245793	3	-	27260156	PATU8988T	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.41478293440495273	[138]	[226,91,156,236]	7	hSpCas9	negative selection	8680319
184245732	184245755	3	-	27260156	PATU8988T	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.7245673816385869	[1255]	[1814,2282,1879,2076]	9	hSpCas9	negative selection	8744599
184245559	184245582	3	-	27260156	PATU8988T	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.419178294386239	[707]	[600,1281,755,1068]	7	hSpCas9	negative selection	8744600
184245467	184245490	3	-	27260156	PATU8988T	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.665672677719019	[174]	[75,317,330,358]	9	hSpCas9	negative selection	8744601
184248808	184248831	3	-	27260156	T47D	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.24044799865297306	[206]	[256,159,170,233]	-5	hSpCas9	negative selection	8801568
184248906	184248929	3	-	27260156	T47D	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.1072683382221018	[201]	[347,273,225,161]	2	hSpCas9	negative selection	8801569
184245770	184245793	3	-	27260156	T47D	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.24733552795334712	[138]	[147,131,112,153]	-5	hSpCas9	negative selection	8801570
184245732	184245755	3	-	27260156	T47D	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.35516744692507807	[1255]	[1180,1087,1185,1123]	-6	hSpCas9	negative selection	8865850
184245559	184245582	3	-	27260156	T47D	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.2764368019818608	[707]	[762,630,609,726]	-6	hSpCas9	negative selection	8865851
184245467	184245490	3	-	27260156	T47D	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.20882223342987327	[174]	[425,156,207,156]	4	hSpCas9	negative selection	8865852
184248808	184248831	3	-	27260156	SU8686	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.3690150192395447	[206]	[151,209,143,114]	-6	hSpCas9	negative selection	8922819
184248906	184248929	3	-	27260156	SU8686	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.5608284092224955	[201]	[336,213,380,247]	8	hSpCas9	negative selection	8922820
184245770	184245793	3	-	27260156	SU8686	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.06394288481843824	[138]	[116,107,152,157]	-1	hSpCas9	negative selection	8922821
184245732	184245755	3	-	27260156	SU8686	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.3935352175381426	[1255]	[915,930,1101,825]	-6	hSpCas9	negative selection	8987101
184245559	184245582	3	-	27260156	SU8686	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.13350632794576361	[707]	[542,540,729,791]	-2	hSpCas9	negative selection	8987102
184245467	184245490	3	-	27260156	SU8686	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	-0.5921096154056149	[174]	[117,81,145,118]	-7	hSpCas9	negative selection	8987103
184248808	184248831	3	-	27260156	SKES1	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.07185187094230927	[206]	[293,230,164,120]	-1	hSpCas9	negative selection	9044070
184248906	184248929	3	-	27260156	SKES1	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.7562723703713408	[201]	[469,364,219,326]	9	hSpCas9	negative selection	9044071
184245770	184245793	3	-	27260156	SKES1	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.05197841006031223	[138]	[232,128,131,95]	1	hSpCas9	negative selection	9044072
184245732	184245755	3	-	27260156	SKES1	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.147660615199952	[1255]	[1230,1277,1087,966]	-3	hSpCas9	negative selection	9108352
184245559	184245582	3	-	27260156	SKES1	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.05474542377108482	[707]	[680,668,739,626]	-1	hSpCas9	negative selection	9108353
184245467	184245490	3	-	27260156	SKES1	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.08925779374505916	[174]	[242,179,173,154]	2	hSpCas9	negative selection	9108354
184248808	184248831	3	-	27260156	TOV112D	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	-0.17211851561245206	[206]	[160,345,167,100]	-3	hSpCas9	negative selection	9165321
184248906	184248929	3	-	27260156	TOV112D	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.18113460088274902	[201]	[195,386,172,197]	3	hSpCas9	negative selection	9165322
184245770	184245793	3	-	27260156	TOV112D	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.28502662857174577	[138]	[102,230,49,100]	-5	hSpCas9	negative selection	9165323
184245732	184245755	3	-	27260156	TOV112D	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.4024842985652606	[1255]	[1018,868,1256,653]	-7	hSpCas9	negative selection	9229603
184245559	184245582	3	-	27260156	TOV112D	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.12630908985481787	[707]	[821,711,682,416]	-2	hSpCas9	negative selection	9229604
184245467	184245490	3	-	27260156	TOV112D	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.3110709914970533	[174]	[203,398,165,145]	6	hSpCas9	negative selection	9229605
184248808	184248831	3	-	27260156	TC71	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.047063193984383744	[206]	[222,197,244,251]	1	hSpCas9	negative selection	9286572
184248906	184248929	3	-	27260156	TC71	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	-0.11185871189199759	[201]	[227,167,171,235]	-3	hSpCas9	negative selection	9286573
184245770	184245793	3	-	27260156	TC71	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	-0.030308159507562937	[138]	[215,92,123,149]	0	hSpCas9	negative selection	9286574
184245732	184245755	3	-	27260156	TC71	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	-0.1644566662472262	[1255]	[1092,1296,1116,1309]	-4	hSpCas9	negative selection	9350854
184245559	184245582	3	-	27260156	TC71	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	-0.02576796325015762	[707]	[548,1010,626,806]	0	hSpCas9	negative selection	9350855
184245467	184245490	3	-	27260156	TC71	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.08260890715641334	[174]	[232,200,191,165]	2	hSpCas9	negative selection	9350856
184248808	184248831	3	-	27260156	TC32	viability	GGAGCCGCGCTACACGCTGCTGG	ALG3	ENSG00000214160	0.3248827223979839	[206]	[272,170,334,218]	6	hSpCas9	negative selection	9407823
184248906	184248929	3	-	27260156	TC32	viability	CTGCGGAAACGCGGCCGGTCCGG	ALG3	ENSG00000214160	0.3475653902628748	[201]	[195,205,258,316]	6	hSpCas9	negative selection	9407824
184245770	184245793	3	-	27260156	TC32	viability	GCCTACATGGCCGAGGTAGAAGG	ALG3	ENSG00000214160	0.45495769826659327	[138]	[208,109,187,224]	7	hSpCas9	negative selection	9407825
184245732	184245755	3	-	27260156	TC32	viability	CTATGACTATACCCAACTGCAGG	ALG3	ENSG00000214160	0.012146929175985699	[1255]	[1010,971,1562,1320]	0	hSpCas9	negative selection	9472105
184245559	184245582	3	-	27260156	TC32	viability	TTGTACTATGCCACCAGCCGAGG	ALG3	ENSG00000214160	0.22752220181738225	[707]	[611,745,1078,711]	4	hSpCas9	negative selection	9472106
184245467	184245490	3	-	27260156	TC32	viability	GATCTATCACCAGACCTGCAAGG	ALG3	ENSG00000214160	0.14367878142949442	[174]	[198,117,307,131]	2	hSpCas9	negative selection	9472107
184243891	184243914	3	+	27869803	HPAFII	viability after 27 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-6.793518734331482	[210]	[0,0,NaN]	-9	hSpCas9	negative selection	9583764
184245271	184245294	3	-	27869803	HPAFII	viability after 27 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-3.4516808155776104	[209]	[20,0,NaN]	-9	hSpCas9	negative selection	9583765
184245542	184245565	3	-	27869803	HPAFII	viability after 27 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-1.9497483176796782	[504]	[71,65,NaN]	-8	hSpCas9	negative selection	9583766
184245722	184245745	3	-	27869803	HPAFII	viability after 27 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-1.6337307782808075	[219]	[63,14,NaN]	-8	hSpCas9	negative selection	9583767
184248930	184248953	3	-	27869803	HPAFII	viability after 27 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.9188742873708412	[254]	[131,19,NaN]	-6	hSpCas9	negative selection	9583768
184249256	184249279	3	-	27869803	HPAFII	viability after 27 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.029343170526612727	[152]	[110,57,NaN]	0	hSpCas9	negative selection	9583769
184243891	184243914	3	+	27869803	HPAFII	viability after 15 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-1.4822056726005266	[210]	[111,61,NaN]	-8	hSpCas9	negative selection	9666213
184245271	184245294	3	-	27869803	HPAFII	viability after 15 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.8412231202970357	[209]	[107,34,NaN]	-9	hSpCas9	negative selection	9666214
184245542	184245565	3	-	27869803	HPAFII	viability after 15 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.6670068405975005	[504]	[585,189,NaN]	-6	hSpCas9	negative selection	9666215
184245722	184245745	3	-	27869803	HPAFII	viability after 15 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.7188648091621224	[219]	[200,107,NaN]	-6	hSpCas9	negative selection	9666216
184248930	184248953	3	-	27869803	HPAFII	viability after 15 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.48559595407827	[254]	[175,207,NaN]	-5	hSpCas9	negative selection	9666217
184249256	184249279	3	-	27869803	HPAFII	viability after 15 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.04946748853954097	[152]	[200,150,NaN]	0	hSpCas9	negative selection	9666218
184243891	184243914	3	+	27869803	ASPC1	viability after 36 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	0.5939748229878528	[558]	[251,212,385]	6	hSpCas9	negative selection	9748662
184245271	184245294	3	-	27869803	ASPC1	viability after 36 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.41591324266121543	[480]	[440,153,124]	4	hSpCas9	negative selection	9748663
184245542	184245565	3	-	27869803	ASPC1	viability after 36 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.034515989132315905	[954]	[118,528,344]	0	hSpCas9	negative selection	9748664
184245722	184245745	3	-	27869803	ASPC1	viability after 36 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	0.28851199575191927	[727]	[729,139,147]	3	hSpCas9	negative selection	9748665
184248930	184248953	3	-	27869803	ASPC1	viability after 36 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.3902743243770233	[631]	[173,357,11]	-4	hSpCas9	negative selection	9748666
184249256	184249279	3	-	27869803	ASPC1	viability after 36 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	1.4257898824305668	[269]	[201,244,292]	9	hSpCas9	negative selection	9748667
184243891	184243914	3	+	27869803	PATU8988S	viability after 35 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-3.8130171163694406	[696]	[7,31,NaN]	-9	hSpCas9	negative selection	9831111
184245271	184245294	3	-	27869803	PATU8988S	viability after 35 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-3.2446331345281467	[363]	[0,29,NaN]	-9	hSpCas9	negative selection	9831112
184245542	184245565	3	-	27869803	PATU8988S	viability after 35 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-1.97548112886381	[986]	[136,64,NaN]	-9	hSpCas9	negative selection	9831113
184245722	184245745	3	-	27869803	PATU8988S	viability after 35 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-1.4855545895111018	[528]	[112,38,NaN]	-8	hSpCas9	negative selection	9831114
184248930	184248953	3	-	27869803	PATU8988S	viability after 35 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.5321363952639369	[369]	[124,80,NaN]	-5	hSpCas9	negative selection	9831115
184249256	184249279	3	-	27869803	PATU8988S	viability after 35 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-1.1475868273091439	[414]	[50,99,NaN]	-8	hSpCas9	negative selection	9831116
184243891	184243914	3	+	27869803	PATU8988S	viability after 31 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-3.5799869682978014	[696]	[24,20,NaN]	-9	hSpCas9	negative selection	9913560
184245271	184245294	3	-	27869803	PATU8988S	viability after 31 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.800034657607728	[363]	[42,39,NaN]	-9	hSpCas9	negative selection	9913561
184245542	184245565	3	-	27869803	PATU8988S	viability after 31 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-1.146636712482084	[986]	[186,165,NaN]	-8	hSpCas9	negative selection	9913562
184245722	184245745	3	-	27869803	PATU8988S	viability after 31 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-0.8508792980726028	[528]	[79,163,NaN]	-7	hSpCas9	negative selection	9913563
184248930	184248953	3	-	27869803	PATU8988S	viability after 31 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-0.43724025558349733	[369]	[115,99,NaN]	-5	hSpCas9	negative selection	9913564
184249256	184249279	3	-	27869803	PATU8988S	viability after 31 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.447506430991847	[414]	[57,201,NaN]	-5	hSpCas9	negative selection	9913565
184243891	184243914	3	+	27869803	HPAFII	viability after 35 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-2.821514725570171	[210]	[0,30,NaN]	-8	hSpCas9	negative selection	9996009
184245271	184245294	3	-	27869803	HPAFII	viability after 35 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-6.732156964669448	[209]	[0,0,NaN]	-9	hSpCas9	negative selection	9996010
184245542	184245565	3	-	27869803	HPAFII	viability after 35 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-2.968943883185223	[504]	[42,20,NaN]	-8	hSpCas9	negative selection	9996011
184245722	184245745	3	-	27869803	HPAFII	viability after 35 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-2.7671982019920036	[219]	[29,0,NaN]	-8	hSpCas9	negative selection	9996012
184248930	184248953	3	-	27869803	HPAFII	viability after 35 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-1.0631360006764157	[254]	[97,20,NaN]	-6	hSpCas9	negative selection	9996013
184249256	184249279	3	-	27869803	HPAFII	viability after 35 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	0.24024473820906417	[152]	[130,46,NaN]	1	hSpCas9	negative selection	9996014
184243891	184243914	3	+	27869803	HPAFII	viability after 31 days	AGCGCCAGTTCACTGTCCAGTGG	ALG3	ENSG00000214160	-3.485629545460582	[210]	[0,20,NaN]	-9	hSpCas9	negative selection	10078458
184245271	184245294	3	-	27869803	HPAFII	viability after 31 days	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-6.275447714709993	[209]	[1,0,NaN]	-9	hSpCas9	negative selection	10078459
184245542	184245565	3	-	27869803	HPAFII	viability after 31 days	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-2.4252785325955433	[504]	[80,21,NaN]	-8	hSpCas9	negative selection	10078460
184245722	184245745	3	-	27869803	HPAFII	viability after 31 days	ACCCAACTGCAGGGTGACACCGG	ALG3	ENSG00000214160	-1.346589123317572	[219]	[71,22,NaN]	-7	hSpCas9	negative selection	10078461
184248930	184248953	3	-	27869803	HPAFII	viability after 31 days	CGCACCGTTAAGATGGCGGCTGG	ALG3	ENSG00000214160	-1.3395271180811426	[254]	[79,30,NaN]	-7	hSpCas9	negative selection	10078462
184249256	184249279	3	-	27869803	HPAFII	viability after 31 days	GATGTTCCCAGCGCAGGCGAAGG	ALG3	ENSG00000214160	-0.19341286348859432	[152]	[65,84,NaN]	-1	hSpCas9	negative selection	10078463
184245289	184245312	3	+	28162770	P31FUJ	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.46956291603906364	[184]	[156]	-4	hSpCas9	negative selection	10109470
184243924	184243947	3	+	28162770	P31FUJ	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-1.460212700517451	[95]	[40]	-7	hSpCas9	negative selection	10109471
184245271	184245294	3	-	28162770	P31FUJ	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.2328022044143785	[269]	[134]	-7	hSpCas9	negative selection	10109472
184243940	184243963	3	+	28162770	P31FUJ	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.12297892646162739	[176]	[190]	-1	hSpCas9	negative selection	10109473
184242830	184242853	3	-	28162770	P31FUJ	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	2.0891258904729835	[4]	[24]	9	hSpCas9	negative selection	10109474
184245777	184245800	3	-	28162770	P31FUJ	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.2903840987200877	[166]	[239]	3	hSpCas9	negative selection	10109475
184245542	184245565	3	-	28162770	P31FUJ	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.15539770072877201	[126]	[133]	-1	hSpCas9	negative selection	10109476
184245248	184245271	3	+	28162770	P31FUJ	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.5858688111106451	[280]	[109]	-7	hSpCas9	negative selection	10109477
184243813	184243836	3	+	28162770	P31FUJ	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.08617729069589543	[214]	[237]	-1	hSpCas9	negative selection	10109478
184244612	184244635	3	+	28162770	P31FUJ	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.11399477437434856	[232]	[252]	-1	hSpCas9	negative selection	10109479
184245289	184245312	3	+	28162770	TF1	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10278836
184243924	184243947	3	+	28162770	TF1	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10278837
184245271	184245294	3	-	28162770	TF1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10278838
184243940	184243963	3	+	28162770	TF1	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10278839
184242830	184242853	3	-	28162770	TF1	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10278840
184245777	184245800	3	-	28162770	TF1	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10278841
184245542	184245565	3	-	28162770	TF1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10278842
184245248	184245271	3	+	28162770	TF1	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10278843
184243813	184243836	3	+	28162770	TF1	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10278844
184244612	184244635	3	+	28162770	TF1	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10278845
184245289	184245312	3	+	28162770	SKM1	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-2.1439297929093675	[74]	[29]	-8	hSpCas9	negative selection	10448202
184243924	184243947	3	+	28162770	SKM1	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.49992639686535667	[9]	[24]	5	hSpCas9	negative selection	10448203
184245271	184245294	3	-	28162770	SKM1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.3814291066360243	[55]	[37]	-7	hSpCas9	negative selection	10448204
184243940	184243963	3	+	28162770	SKM1	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.15985095526773507	[39]	[78]	1	hSpCas9	negative selection	10448205
184242830	184242853	3	-	28162770	SKM1	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10448206
184245777	184245800	3	-	28162770	SKM1	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-1.3264742808827936	[60]	[42]	-7	hSpCas9	negative selection	10448207
184245542	184245565	3	-	28162770	SKM1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.7371128004354924	[32]	[34]	-5	hSpCas9	negative selection	10448208
184245248	184245271	3	+	28162770	SKM1	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.7395395378300325	[67]	[35]	-8	hSpCas9	negative selection	10448209
184243813	184243836	3	+	28162770	SKM1	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.5463672554085783	[37]	[45]	-4	hSpCas9	negative selection	10448210
184244612	184244635	3	+	28162770	SKM1	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.5809935985182106	[65]	[77]	-4	hSpCas9	negative selection	10448211
184245289	184245312	3	+	28162770	SKM1	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-2.1439297929093675	[74]	[29]	-8	hSpCas9	negative selection	10617568
184243924	184243947	3	+	28162770	SKM1	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.49992639686535667	[9]	[24]	5	hSpCas9	negative selection	10617569
184245271	184245294	3	-	28162770	SKM1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.3814291066360243	[55]	[37]	-7	hSpCas9	negative selection	10617570
184243940	184243963	3	+	28162770	SKM1	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.15985095526773507	[39]	[78]	1	hSpCas9	negative selection	10617571
184242830	184242853	3	-	28162770	SKM1	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10617572
184245777	184245800	3	-	28162770	SKM1	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-1.3264742808827936	[60]	[42]	-7	hSpCas9	negative selection	10617573
184245542	184245565	3	-	28162770	SKM1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.7371128004354924	[32]	[34]	-5	hSpCas9	negative selection	10617574
184245248	184245271	3	+	28162770	SKM1	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.7395395378300325	[67]	[35]	-8	hSpCas9	negative selection	10617575
184243813	184243836	3	+	28162770	SKM1	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.5463672554085783	[37]	[45]	-4	hSpCas9	negative selection	10617576
184244612	184244635	3	+	28162770	SKM1	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.5809935985182106	[65]	[77]	-4	hSpCas9	negative selection	10617577
184245289	184245312	3	+	28162770	PL21	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.25155635536837184	[185]	[67]	-2	hSpCas9	negative selection	10786934
184243924	184243947	3	+	28162770	PL21	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-2.6578413806382524	[57]	[3]	-9	hSpCas9	negative selection	10786935
184245271	184245294	3	-	28162770	PL21	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.5628211882098304	[223]	[65]	-4	hSpCas9	negative selection	10786936
184243940	184243963	3	+	28162770	PL21	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.43280037127959525	[159]	[93]	4	hSpCas9	negative selection	10786937
184242830	184242853	3	-	28162770	PL21	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.7998603855106801	[3]	[0]	-5	hSpCas9	negative selection	10786938
184245777	184245800	3	-	28162770	PL21	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	1.8104576894873705	[187]	[286]	9	hSpCas9	negative selection	10786939
184245542	184245565	3	-	28162770	PL21	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.4628253982331094	[56]	[17]	-3	hSpCas9	negative selection	10786940
184245248	184245271	3	+	28162770	PL21	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.9408726950377537	[246]	[27]	-8	hSpCas9	negative selection	10786941
184243813	184243836	3	+	28162770	PL21	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.1711161927616104	[118]	[45]	-1	hSpCas9	negative selection	10786942
184244612	184244635	3	+	28162770	PL21	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.1963777968187258	[128]	[48]	-1	hSpCas9	negative selection	10786943
184245289	184245312	3	+	28162770	P31FUJ	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.46956291603906364	[184]	[156]	-4	hSpCas9	negative selection	10956300
184243924	184243947	3	+	28162770	P31FUJ	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-1.460212700517451	[95]	[40]	-7	hSpCas9	negative selection	10956301
184245271	184245294	3	-	28162770	P31FUJ	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-1.2328022044143785	[269]	[134]	-7	hSpCas9	negative selection	10956302
184243940	184243963	3	+	28162770	P31FUJ	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.12297892646162739	[176]	[190]	-1	hSpCas9	negative selection	10956303
184242830	184242853	3	-	28162770	P31FUJ	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	2.0891258904729835	[4]	[24]	9	hSpCas9	negative selection	10956304
184245777	184245800	3	-	28162770	P31FUJ	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.2903840987200877	[166]	[239]	3	hSpCas9	negative selection	10956305
184245542	184245565	3	-	28162770	P31FUJ	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.15539770072877201	[126]	[133]	-1	hSpCas9	negative selection	10956306
184245248	184245271	3	+	28162770	P31FUJ	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.5858688111106451	[280]	[109]	-7	hSpCas9	negative selection	10956307
184243813	184243836	3	+	28162770	P31FUJ	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.08617729069589543	[214]	[237]	-1	hSpCas9	negative selection	10956308
184244612	184244635	3	+	28162770	P31FUJ	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.11399477437434856	[232]	[252]	-1	hSpCas9	negative selection	10956309
184245289	184245312	3	+	28162770	OCIAML5	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	0.553519453070275	[133]	[354]	5	hSpCas9	negative selection	11125666
184243924	184243947	3	+	28162770	OCIAML5	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-0.36331938540214403	[61]	[86]	-3	hSpCas9	negative selection	11125667
184245271	184245294	3	-	28162770	OCIAML5	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.6369715098586236	[113]	[319]	5	hSpCas9	negative selection	11125668
184243940	184243963	3	+	28162770	OCIAML5	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.262254670481445	[98]	[148]	-2	hSpCas9	negative selection	11125669
184242830	184242853	3	-	28162770	OCIAML5	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.682141569421685	[7]	[8]	-4	hSpCas9	negative selection	11125670
184245777	184245800	3	-	28162770	OCIAML5	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.4183853065322799	[96]	[233]	3	hSpCas9	negative selection	11125671
184245542	184245565	3	-	28162770	OCIAML5	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	2.3573867947649525	[35]	[332]	9	hSpCas9	negative selection	11125672
184245248	184245271	3	+	28162770	OCIAML5	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	0.10010490404538802	[137]	[266]	0	hSpCas9	negative selection	11125673
184243813	184243836	3	+	28162770	OCIAML5	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	0.14793342913600296	[97]	[195]	1	hSpCas9	negative selection	11125674
184244612	184244635	3	+	28162770	OCIAML5	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	0.1431164128382273	[149]	[298]	1	hSpCas9	negative selection	11125675
184245289	184245312	3	+	28162770	EOL1	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.25831628557927583	[335]	[147]	-2	hSpCas9	negative selection	11295032
184243924	184243947	3	+	28162770	EOL1	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	1.3293895037434897	[70]	[93]	9	hSpCas9	negative selection	11295033
184245271	184245294	3	-	28162770	EOL1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.04775920775143511	[414]	[225]	0	hSpCas9	negative selection	11295034
184243940	184243963	3	+	28162770	EOL1	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.46982657081920853	[343]	[250]	4	hSpCas9	negative selection	11295035
184242830	184242853	3	-	28162770	EOL1	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	0.6707911793247514	[30]	[25]	6	hSpCas9	negative selection	11295036
184245777	184245800	3	-	28162770	EOL1	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.9322013441139698	[375]	[377]	7	hSpCas9	negative selection	11295037
184245542	184245565	3	-	28162770	EOL1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.9980768069924998	[152]	[160]	8	hSpCas9	negative selection	11295038
184245248	184245271	3	+	28162770	EOL1	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	0.37200674854175586	[351]	[239]	3	hSpCas9	negative selection	11295039
184243813	184243836	3	+	28162770	EOL1	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.5222522900930969	[198]	[72]	-4	hSpCas9	negative selection	11295040
184244612	184244635	3	+	28162770	EOL1	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	0.3435651217619239	[180]	[120]	3	hSpCas9	negative selection	11295041
184245289	184245312	3	+	28162770	MOLM13	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	0.5721003765327127	[266]	[286]	4	hSpCas9	negative selection	11464398
184243924	184243947	3	+	28162770	MOLM13	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-0.1995352793685503	[80]	[50]	-1	hSpCas9	negative selection	11464399
184245271	184245294	3	-	28162770	MOLM13	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.507905060392458	[319]	[328]	4	hSpCas9	negative selection	11464400
184243940	184243963	3	+	28162770	MOLM13	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	1.5466664949286961	[195]	[413]	9	hSpCas9	negative selection	11464401
184242830	184242853	3	-	28162770	MOLM13	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	0.6793934867382907	[18]	[21]	5	hSpCas9	negative selection	11464402
184245777	184245800	3	-	28162770	MOLM13	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.8471506514978927	[295]	[384]	6	hSpCas9	negative selection	11464403
184245542	184245565	3	-	28162770	MOLM13	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	1.3086907866953248	[133]	[239]	8	hSpCas9	negative selection	11464404
184245248	184245271	3	+	28162770	MOLM13	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.9888991309350086	[408]	[148]	-5	hSpCas9	negative selection	11464405
184243813	184243836	3	+	28162770	MOLM13	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.6056917508365285	[180]	[85]	-3	hSpCas9	negative selection	11464406
184244612	184244635	3	+	28162770	MOLM13	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	0.09819486772648912	[260]	[201]	0	hSpCas9	negative selection	11464407
184245289	184245312	3	+	28162770	HEL	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.5594500186129099	[259]	[112]	-4	hSpCas9	negative selection	11633764
184243924	184243947	3	+	28162770	HEL	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-1.4630558320222402	[98]	[22]	-7	hSpCas9	negative selection	11633765
184245271	184245294	3	-	28162770	HEL	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	0.6213016613380651	[338]	[333]	5	hSpCas9	negative selection	11633766
184243940	184243963	3	+	28162770	HEL	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.6573856079647583	[195]	[197]	5	hSpCas9	negative selection	11633767
184242830	184242853	3	-	28162770	HEL	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	1.7302016732506966	[7]	[16]	9	hSpCas9	negative selection	11633768
184245777	184245800	3	-	28162770	HEL	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	1.1054730733104972	[237]	[327]	8	hSpCas9	negative selection	11633769
184245542	184245565	3	-	28162770	HEL	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.5594833283510047	[106]	[100]	5	hSpCas9	negative selection	11633770
184245248	184245271	3	+	28162770	HEL	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.07996606904067957	[301]	[182]	0	hSpCas9	negative selection	11633771
184243813	184243836	3	+	28162770	HEL	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	0.0011928029128333018	[155]	[99]	0	hSpCas9	negative selection	11633772
184244612	184244635	3	+	28162770	HEL	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.24865067006797373	[242]	[130]	-2	hSpCas9	negative selection	11633773
184245289	184245312	3	+	28162770	MV411	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	0.16235604989300717	[226]	[213]	1	hSpCas9	negative selection	11803130
184243924	184243947	3	+	28162770	MV411	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-0.9014258351317077	[50]	[22]	-6	hSpCas9	negative selection	11803131
184245271	184245294	3	-	28162770	MV411	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	1.1731319920540897	[248]	[472]	9	hSpCas9	negative selection	11803132
184243940	184243963	3	+	28162770	MV411	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.3357934252036223	[189]	[201]	3	hSpCas9	negative selection	11803133
184242830	184242853	3	-	28162770	MV411	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	0.7328643779530171	[14]	[20]	6	hSpCas9	negative selection	11803134
184245777	184245800	3	-	28162770	MV411	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.6002596536159215	[230]	[294]	5	hSpCas9	negative selection	11803135
184245542	184245565	3	-	28162770	MV411	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.22204773251844512	[125]	[90]	-2	hSpCas9	negative selection	11803136
184245248	184245271	3	+	28162770	MV411	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	0.44710989561913966	[255]	[293]	4	hSpCas9	negative selection	11803137
184243813	184243836	3	+	28162770	MV411	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	0.5646277266634746	[121]	[151]	5	hSpCas9	negative selection	11803138
184244612	184244635	3	+	28162770	MV411	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.34980327971681763	[176]	[116]	-3	hSpCas9	negative selection	11803139
184245289	184245312	3	+	28162770	MONOMAC1	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-0.9967381965737223	[140]	[80]	-7	hSpCas9	negative selection	11972496
184243924	184243947	3	+	28162770	MONOMAC1	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-2.6750841438641975	[38]	[6]	-9	hSpCas9	negative selection	11972497
184245271	184245294	3	-	28162770	MONOMAC1	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.6120743463383974	[179]	[134]	-5	hSpCas9	negative selection	11972498
184243940	184243963	3	+	28162770	MONOMAC1	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.30931581896523597	[87]	[124]	3	hSpCas9	negative selection	11972499
184242830	184242853	3	-	28162770	MONOMAC1	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.19703684705955382	[7]	[7]	-2	hSpCas9	negative selection	11972500
184245777	184245800	3	-	28162770	MONOMAC1	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-0.6157500044817956	[130]	[97]	-5	hSpCas9	negative selection	11972501
184245542	184245565	3	-	28162770	MONOMAC1	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.2235388357607201	[64]	[86]	2	hSpCas9	negative selection	11972502
184245248	184245271	3	+	28162770	MONOMAC1	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.8660636125691843	[158]	[99]	-6	hSpCas9	negative selection	11972503
184243813	184243836	3	+	28162770	MONOMAC1	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.05617431121970404	[116]	[128]	0	hSpCas9	negative selection	11972504
184244612	184244635	3	+	28162770	MONOMAC1	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.06458655103590433	[103]	[113]	0	hSpCas9	negative selection	11972505
184245289	184245312	3	+	28162770	OCIAML2	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	0.36671983711328027	[33]	[242]	3	hSpCas9	negative selection	12141862
184243924	184243947	3	+	28162770	OCIAML2	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	0.48872819026049297	[8]	[69]	5	hSpCas9	negative selection	12141863
184245271	184245294	3	-	28162770	OCIAML2	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-0.1175632185458948	[54]	[280]	-1	hSpCas9	negative selection	12141864
184243940	184243963	3	+	28162770	OCIAML2	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	0.5033749662248942	[27]	[219]	5	hSpCas9	negative selection	12141865
184242830	184242853	3	-	28162770	OCIAML2	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-0.7336642310759549	[5]	[19]	-5	hSpCas9	negative selection	12141866
184245777	184245800	3	-	28162770	OCIAML2	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	0.22425036755703032	[39]	[258]	2	hSpCas9	negative selection	12141867
184245542	184245565	3	-	28162770	OCIAML2	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	0.08879758337185728	[18]	[111]	0	hSpCas9	negative selection	12141868
184245248	184245271	3	+	28162770	OCIAML2	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-0.8939825927330087	[57]	[172]	-6	hSpCas9	negative selection	12141869
184243813	184243836	3	+	28162770	OCIAML2	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	0.48630145286595283	[16]	[131]	5	hSpCas9	negative selection	12141870
184244612	184244635	3	+	28162770	OCIAML2	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	-0.25303839016953467	[42]	[199]	-2	hSpCas9	negative selection	12141871
184245289	184245312	3	+	28162770	OCIAML3	viability	GCCGCAGCACAAAGATGGAGTGG	ALG3	ENSG00000214160	-3.0965079808533464	[50]	[17]	-9	hSpCas9	negative selection	12311228
184243924	184243947	3	+	28162770	OCIAML3	viability	GGCGGCCAAGGTCAAAGGAGCGG	ALG3	ENSG00000214160	-1.009045139603007	[11]	[17]	-6	hSpCas9	negative selection	12311229
184245271	184245294	3	-	28162770	OCIAML3	viability	GCGGCTCTTCAATGACCCAGTGG	ALG3	ENSG00000214160	-2.937962041541524	[65]	[25]	-9	hSpCas9	negative selection	12311230
184243940	184243963	3	+	28162770	OCIAML3	viability	GGAGCGGGACAGGTAGCCGCTGG	ALG3	ENSG00000214160	-0.39761042752065984	[47]	[109]	-3	hSpCas9	negative selection	12311231
184242830	184242853	3	-	28162770	OCIAML3	viability	TGTGGGCCATGCCTGCACGCTGG	ALG3	ENSG00000214160	-1.17897014104532	[2]	[3]	-7	hSpCas9	negative selection	12311232
184245777	184245800	3	-	28162770	OCIAML3	viability	CTGGAAGGCCTACATGGCCGAGG	ALG3	ENSG00000214160	-0.25297072248909624	[59]	[151]	-2	hSpCas9	negative selection	12311233
184245542	184245565	3	-	28162770	OCIAML3	viability	CCGAGGCACTGACATCCGCATGG	ALG3	ENSG00000214160	-0.5433815672541952	[27]	[57]	-4	hSpCas9	negative selection	12311234
184245248	184245271	3	+	28162770	OCIAML3	viability	ACTGAGGAAGAGCAGCACCATGG	ALG3	ENSG00000214160	-1.7810931929246583	[73]	[64]	-8	hSpCas9	negative selection	12311235
184243813	184243836	3	+	28162770	OCIAML3	viability	ACAGCAGGAGCAGGGTGAGGTGG	ALG3	ENSG00000214160	-0.7227409544463661	[40]	[74]	-5	hSpCas9	negative selection	12311236
184244612	184244635	3	+	28162770	OCIAML3	viability	CACAGATTCCCAGCTTGGGGAGG	ALG3	ENSG00000214160	0.24249362739295732	[41]	[149]	2	hSpCas9	negative selection	12311237