Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9474
• Symbol: Atg5
• Description: autophagy related 5

DataSource: http://genomecrispr.dkfz.de/#!/results/Atg5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
106279672	106279695	6	-	26472758	Jiyoye	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	0.7291034763932358	[27]	[34]	5	hSpCas9	negative selection	11855
106186598	106186621	6	+	26472758	Jiyoye	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.44714716329849125	[319]	[176]	-3	hSpCas9	negative selection	11856
106316173	106316196	6	-	26472758	Jiyoye	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.742278865140969	[217]	[274]	5	hSpCas9	negative selection	11857
106308363	106308386	6	-	26472758	Jiyoye	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.27563444261342734	[121]	[75]	-2	hSpCas9	negative selection	11858
106248203	106248226	6	-	26472758	Jiyoye	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	-0.3833712528651767	[191]	[110]	-3	hSpCas9	negative selection	11859
106201987	106202010	6	+	26472758	Jiyoye	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.0892790406375612	[267]	[214]	0	hSpCas9	negative selection	11860
106201971	106201994	6	-	26472758	Jiyoye	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	-0.35532530476747015	[189]	[111]	-3	hSpCas9	negative selection	11861
106202044	106202067	6	-	26472758	Jiyoye	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.680287459744466	[50]	[11]	-8	hSpCas9	negative selection	11862
106202016	106202039	6	-	26472758	Jiyoye	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	2.2331459817308246	[21]	[77]	9	hSpCas9	negative selection	11863
106279771	106279794	6	+	26472758	Jiyoye	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.46262589536742516	[359]	[196]	-3	hSpCas9	negative selection	11864
106279672	106279695	6	-	26472758	KBM7	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.34200695704605044	[284,203]	[115,65]	-3	hSpCas9	negative selection	202973
106186598	106186621	6	+	26472758	KBM7	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.7365018426421256	[1192,1205]	[333,345]	-6	hSpCas9	negative selection	202974
106316173	106316196	6	-	26472758	KBM7	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.3405496106395758	[1414,1244]	[548,442]	-3	hSpCas9	negative selection	202975
106308363	106308386	6	-	26472758	KBM7	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.22593069945516053	[758,520]	[479,227]	2	hSpCas9	negative selection	202976
106248203	106248226	6	-	26472758	KBM7	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.9852624840474415	[502,278]	[353,355]	9	hSpCas9	negative selection	202977
106201987	106202010	6	+	26472758	KBM7	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.4758712326048009	[1262,955]	[1024,444]	5	hSpCas9	negative selection	202978
106201971	106201994	6	-	26472758	KBM7	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.27306482991997105	[704,521]	[345,343]	3	hSpCas9	negative selection	202979
106202044	106202067	6	-	26472758	KBM7	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.7619145162374572	[81,61]	[30,79]	8	hSpCas9	negative selection	202980
106202016	106202039	6	-	26472758	KBM7	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.12828317161489225	[280,440]	[140,234]	1	hSpCas9	negative selection	202981
106279771	106279794	6	+	26472758	KBM7	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.1636045482044861	[1439,1386]	[989,528]	1	hSpCas9	negative selection	202982
106279672	106279695	6	-	26472758	Raji	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.777973898685278	[132]	[8]	-8	hSpCas9	negative selection	394091
106186598	106186621	6	+	26472758	Raji	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.09159749935279593	[651]	[141]	-1	hSpCas9	negative selection	394092
106316173	106316196	6	-	26472758	Raji	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.5705956287283149	[588]	[202]	5	hSpCas9	negative selection	394093
106308363	106308386	6	-	26472758	Raji	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.03606925470752168	[242]	[54]	0	hSpCas9	negative selection	394094
106248203	106248226	6	-	26472758	Raji	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.4956541250896579	[271]	[88]	5	hSpCas9	negative selection	394095
106201987	106202010	6	+	26472758	Raji	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.753746580758899	[643]	[251]	7	hSpCas9	negative selection	394096
106201971	106201994	6	-	26472758	Raji	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.37336522525772997	[325]	[97]	3	hSpCas9	negative selection	394097
106202044	106202067	6	-	26472758	Raji	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	1.5768688186748192	[12]	[8]	9	hSpCas9	negative selection	394098
106202016	106202039	6	-	26472758	Raji	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.7603644595234068	[144]	[56]	7	hSpCas9	negative selection	394099
106279771	106279794	6	+	26472758	Raji	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.7827359391326449	[530]	[211]	7	hSpCas9	negative selection	394100
106279672	106279695	6	-	26472758	K562	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	0.01468433098883104	[196]	[167]	0	hSpCas9	negative selection	585209
106186598	106186621	6	+	26472758	K562	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.20000257839349111	[991]	[728]	-1	hSpCas9	negative selection	585210
106316173	106316196	6	-	26472758	K562	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.56208164563826	[1083]	[1350]	4	hSpCas9	negative selection	585211
106308363	106308386	6	-	26472758	K562	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.12369282934444087	[435]	[400]	0	hSpCas9	negative selection	585212
106248203	106248226	6	-	26472758	K562	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.8306495318019371	[378]	[568]	7	hSpCas9	negative selection	585213
106201987	106202010	6	+	26472758	K562	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.6833333289632311	[778]	[1055]	5	hSpCas9	negative selection	585214
106201971	106201994	6	-	26472758	K562	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.01214103326718785	[658]	[560]	0	hSpCas9	negative selection	585215
106202044	106202067	6	-	26472758	K562	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.9157959802050766	[53]	[85]	7	hSpCas9	negative selection	585216
106202016	106202039	6	-	26472758	K562	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.6477744218976552	[154]	[204]	5	hSpCas9	negative selection	585217
106279771	106279794	6	+	26472758	K562	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.5882246729214535	[1177]	[1494]	5	hSpCas9	negative selection	585218
106202028	106202051	6	+	26627737	DLD1	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	-0.8794598398123964	[276]	[77,50,16]	-7	hSpCas9	negative selection	829938
106279784	106279807	6	+	26627737	DLD1	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.264733493251174	[522]	[292,218,93]	2	hSpCas9	negative selection	829941
106202028	106202051	6	+	26627737	GBM cells	viability after 5 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.09155895282808135	[104]	[63,55]	1	hSpCas9	negative selection	912253
106279784	106279807	6	+	26627737	GBM cells	viability after 5 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.13169406501688644	[256]	[152,148]	2	hSpCas9	negative selection	912256
106202028	106202051	6	+	26627737	GBM cells	viability after 13 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.6286146220161896	[104]	[113,66]	7	hSpCas9	negative selection	994568
106279784	106279807	6	+	26627737	GBM cells	viability after 13 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.4178029956781776	[256]	[268,118]	5	hSpCas9	negative selection	994571
106202028	106202051	6	+	26627737	GBM cells	viability after 21 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.009804172565965219	[104]	[58,55]	0	hSpCas9	negative selection	1076883
106279784	106279807	6	+	26627737	GBM cells	viability after 21 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-0.604619807042835	[256]	[95,87]	-5	hSpCas9	negative selection	1076886
106202028	106202051	6	+	26627737	RPE1	viability after 9 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	2.635812818482322	[216]	[199,708]	9	hSpCas9	negative selection	1159198
106279784	106279807	6	+	26627737	RPE1	viability after 9 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.7534048492763288	[846]	[391,517]	5	hSpCas9	negative selection	1159201
106202028	106202051	6	+	26627737	RPE1	viability after 12 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	3.6458610377865557	[216]	[279,1205]	9	hSpCas9	negative selection	1241513
106279784	106279807	6	+	26627737	RPE1	viability after 12 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.9739320561289178	[846]	[360,537]	6	hSpCas9	negative selection	1241516
106202028	106202051	6	+	26627737	RPE1	viability after 15 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	4.566754294026018	[216]	[399,2471]	9	hSpCas9	negative selection	1323828
106279784	106279807	6	+	26627737	RPE1	viability after 15 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.5435208463144054	[846]	[364,333]	3	hSpCas9	negative selection	1323831
106202028	106202051	6	+	26627737	RPE1	viability after 18 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	4.75368305683622	[216]	[496,2736]	9	hSpCas9	negative selection	1406143
106279784	106279807	6	+	26627737	RPE1	viability after 18 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.8484728564671903	[846]	[442,377]	5	hSpCas9	negative selection	1406146
106202028	106202051	6	+	26627737	HeLa	viability after 8 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.5933541600655003	[148]	[113,158,28]	5	hSpCas9	negative selection	1488458
106279784	106279807	6	+	26627737	HeLa	viability after 8 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.3309998943538657	[377]	[148,237,219]	3	hSpCas9	negative selection	1488461
106202028	106202051	6	+	26627737	HeLa	viability after 12 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.3476695104590637	[148]	[1,142,80]	3	hSpCas9	negative selection	1570773
106279784	106279807	6	+	26627737	HeLa	viability after 12 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.5298811466750597	[377]	[145,237,288]	4	hSpCas9	negative selection	1570776
106202028	106202051	6	+	26627737	HeLa	viability after 15 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.35819621334795193	[148]	[40,147,41]	3	hSpCas9	negative selection	1653088
106279784	106279807	6	+	26627737	HeLa	viability after 15 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.3324195726019974	[377]	[174,206,199]	3	hSpCas9	negative selection	1653091
106202028	106202051	6	+	26627737	HeLa	viability after 18 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.4312177642915278	[148]	[30,127,41]	3	hSpCas9	negative selection	1735403
106279784	106279807	6	+	26627737	HeLa	viability after 18 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.33341304277928496	[377]	[113,175,199]	3	hSpCas9	negative selection	1735406
106202028	106202051	6	+	26627737	HCT116	viability after 6 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	2.1806016553216545	[365]	[265,257]	9	hSpCas9	negative selection	1817718
106279784	106279807	6	+	26627737	HCT116	viability after 6 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-1.0731311753016177	[528]	[83,14]	-6	hSpCas9	negative selection	1817721
106202028	106202051	6	+	26627737	HCT116	viability after 8 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.13740377173992024	[211]	[120,107,155]	1	hSpCas9	negative selection	1900033
106279784	106279807	6	+	26627737	HCT116	viability after 8 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.03925184446459545	[229]	[129,155,104]	0	hSpCas9	negative selection	1900036
106202028	106202051	6	+	26627737	HCT116	viability after 9 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	-0.4543877572332552	[365]	[134,20]	-3	hSpCas9	negative selection	1982348
106279784	106279807	6	+	26627737	HCT116	viability after 9 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.8590331488305266	[528]	[320,204]	6	hSpCas9	negative selection	1982351
106202028	106202051	6	+	26627737	HCT116	viability after 12 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.4011976890445005	[211]	[73,195,178]	4	hSpCas9	negative selection	2064663
106279784	106279807	6	+	26627737	HCT116	viability after 12 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.8799223595700005	[229]	[301,167,188]	7	hSpCas9	negative selection	2064666
106202028	106202051	6	+	26627737	HCT116	viability after 15 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.30489259148254677	[211]	[158,121,170]	3	hSpCas9	negative selection	2146978
106279784	106279807	6	+	26627737	HCT116	viability after 15 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-0.04236953127087567	[229]	[118,163,100]	0	hSpCas9	negative selection	2146981
106202028	106202051	6	+	26627737	HCT116	viability after 18 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.366890764144901	[211]	[103,278,415]	8	hSpCas9	negative selection	2229293
106279784	106279807	6	+	26627737	HCT116	viability after 18 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.5484001427373965	[229]	[171,88,234]	4	hSpCas9	negative selection	2229296
106316168	106316190	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.09002265981325971	[2638,2024,2453]	[0,0,0]	0	hSpCas9	positive selection	2380575
106316168	106316190	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.09002265981325971	[2638,2024,2453]	[0,0,0]	0	hSpCas9	positive selection	2380576
106308458	106308483	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCAAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3670752115082081	[3273,3476,2994]	[0,0,0]	-3	hSpCas9	positive selection	2380577
106308458	106308483	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCAAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3670752115082081	[3273,3476,2994]	[0,0,0]	-3	hSpCas9	positive selection	2380578
106308425	106308446	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGAAAAAGCACTTTCAGAAGG	ATG5	ENSG00000057663	11.187539080126703	[9076,6636,7922]	[452,13305,8047]	9	hSpCas9	positive selection	2380579
106308425	106308446	6	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGAAAAAGCACTTTCAGAAGG	ATG5	ENSG00000057663	11.187539080126703	[9076,6636,7922]	[452,13305,8047]	9	hSpCas9	positive selection	2380580
106316168	106316190	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.09025114434942862	[2638,2024,2453]	[0,0,0]	0	hSpCas9	positive selection	2381691
106316168	106316190	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.09025114434942862	[2638,2024,2453]	[0,0,0]	0	hSpCas9	positive selection	2381692
106308458	106308483	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.36762377953066583	[3273,3476,2994]	[0,0,0]	-4	hSpCas9	positive selection	2381693
106308458	106308483	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.36762377953066583	[3273,3476,2994]	[0,0,0]	-4	hSpCas9	positive selection	2381694
106308425	106308446	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGAAAAAGCACTTTCAGAAGG	ATG5	ENSG00000057663	5.660911393607039	[9076,6636,7922]	[153,316,1]	8	hSpCas9	positive selection	2381695
106308425	106308446	6	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGAAAAAGCACTTTCAGAAGG	ATG5	ENSG00000057663	5.660911393607039	[9076,6636,7922]	[153,316,1]	8	hSpCas9	positive selection	2381696
106269667	106269690	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGGGCCGGCAGGGCCGGCCGG	ATG5	ENSG00000057663	0.689474547259024	[3,3]	[0,1]	3	dCas9-VP64	positive selection	2416089
106216782	106216805	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAGAGGATCACTTGAGCCAGG	ATG5	ENSG00000057663	0.169734143386715	[57,44]	[12,10]	0	dCas9-VP64	positive selection	2416868
106248736	106248759	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGACCAGCCTGACCAACATGG	ATG5	ENSG00000057663	-0.8115413669010654	[119,148]	[17,14]	-4	dCas9-VP64	positive selection	2416983
106325520	106325543	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGTACCCTACTCCAAGCTATGG	ATG5	ENSG00000057663	1.9943606648779801	[87,604]	[56,578]	7	dCas9-VP64	positive selection	2423756
106325592	106325615	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCTTGCCCCGCCGCCCCACCGG	ATG5	ENSG00000057663	0.8693310614055623	[217,124]	[85,48]	3	dCas9-VP64	positive selection	2423757
106325573	106325596	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACGCCCAGATTCCGCGCTCCGG	ATG5	ENSG00000057663	5.0411267503944535	[21,207]	[54,1702]	9	dCas9-VP64	positive selection	2423758
106269667	106269690	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGGGCCGGCAGGGCCGGCCGG	ATG5	ENSG00000057663	-0.5551230422316469	[0,60]	[1,9]	-5	dCas9-VP64	positive selection	2511344
106216782	106216805	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAGAGGATCACTTGAGCCAGG	ATG5	ENSG00000057663	-0.04478500742304492	[42,58]	[7,21]	0	dCas9-VP64	positive selection	2512123
106248736	106248759	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGACCAGCCTGACCAACATGG	ATG5	ENSG00000057663	-0.5467869097718738	[166,210]	[42,40]	-5	dCas9-VP64	positive selection	2512238
106325520	106325543	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGTACCCTACTCCAAGCTATGG	ATG5	ENSG00000057663	0.14929862399591487	[53,107]	[39,17]	1	dCas9-VP64	positive selection	2519011
106325592	106325615	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCTTGCCCCGCCGCCCCACCGG	ATG5	ENSG00000057663	0.3170576765364945	[162,150]	[61,65]	2	dCas9-VP64	positive selection	2519012
106325573	106325596	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACGCCCAGATTCCGCGCTCCGG	ATG5	ENSG00000057663	0.6006750484960162	[98,19]	[39,18]	4	dCas9-VP64	positive selection	2519013
106293049	106293072	6	-	27260157	DLD1	viability	CATCAAGTTCAGCTCTTCCTTGG	ATG5	ENSG00000057663	0.202112715376046	[]	[]	3	hSpCas9	negative selection	2578631
106202034	106202057	6	-	27260157	DLD1	viability	TTTCGTCCTGTGGCTGCAGATGG	ATG5	ENSG00000057663	-1.41183005675971	[]	[]	-8	hSpCas9	negative selection	2581049
106186609	106186632	6	-	27260157	DLD1	viability	TGTTGGAAACACCTCTGCAGTGG	ATG5	ENSG00000057663	-0.660808114754164	[]	[]	-5	hSpCas9	negative selection	2582455
106201971	106201994	6	+	27260157	DLD1	viability	CCTTCAGGATCAATAGCAGAAGG	ATG5	ENSG00000057663	0.0669175436568209	[]	[]	3	hSpCas9	negative selection	2583789
106201956	106201979	6	+	27260157	DLD1	viability	TTGCTGATTGTATTACCTTCAGG	ATG5	ENSG00000057663	0.586985182969369	[]	[]	8	hSpCas9	negative selection	2584182
106202044	106202067	6	-	27260157	DLD1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-0.26450550573298	[]	[]	-2	hSpCas9	negative selection	2585911
106308363	106308386	6	-	27260157	DLD1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.172732924107848	[]	[]	3	hSpCas9	negative selection	2605273
106202028	106202051	6	+	27260157	DLD1	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.434008878268169	[]	[]	7	hSpCas9	negative selection	2609109
106186535	106186558	6	+	27260157	DLD1	viability	ATCCTTCAATCTGTTGGCTGTGG	ATG5	ENSG00000057663	0.631774126923908	[]	[]	8	hSpCas9	negative selection	2609178
106316168	106316191	6	-	27260157	DLD1	viability	GTGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	-1.03335264839065	[]	[]	-7	hSpCas9	negative selection	2609673
106202016	106202039	6	-	27260157	DLD1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.994135184131123	[]	[]	-7	hSpCas9	negative selection	2614298
106186598	106186621	6	+	27260157	DLD1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.26541649497914	[]	[]	-7	hSpCas9	negative selection	2615962
106186613	106186636	6	+	27260157	DLD1	viability	TGCAGAGGTGTTTCCAACATTGG	ATG5	ENSG00000057663	0.506370532945969	[]	[]	8	hSpCas9	negative selection	2619480
106293077	106293100	6	+	27260157	DLD1	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.322028457435267	[]	[]	4	hSpCas9	negative selection	2623657
106186584	106186607	6	-	27260157	DLD1	viability	GAGTGAACATCTGAGCTACCCGG	ATG5	ENSG00000057663	1.23033316325562	[]	[]	9	hSpCas9	negative selection	2623708
106279784	106279807	6	+	27260157	DLD1	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.769090916835166	[]	[]	8	hSpCas9	negative selection	2624209
106293032	106293055	6	+	27260157	DLD1	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.541393261334676	[]	[]	8	hSpCas9	negative selection	2646218
106248203	106248226	6	-	27260157	DLD1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.769092274326627	[]	[]	8	hSpCas9	negative selection	2648583
106186537	106186560	6	-	27260157	DLD1	viability	TCCCACAGCCAACAGATTGAAGG	ATG5	ENSG00000057663	-0.0353190871753812	[]	[]	0	hSpCas9	negative selection	2649096
106293049	106293072	6	-	27260157	HT1080	viability	CATCAAGTTCAGCTCTTCCTTGG	ATG5	ENSG00000057663	0.360449093910645	[]	[]	3	hSpCas9	negative selection	2654761
106202034	106202057	6	-	27260157	HT1080	viability	TTTCGTCCTGTGGCTGCAGATGG	ATG5	ENSG00000057663	-1.23415934091445	[]	[]	-9	hSpCas9	negative selection	2657179
106186609	106186632	6	-	27260157	HT1080	viability	TGTTGGAAACACCTCTGCAGTGG	ATG5	ENSG00000057663	-0.645152527729902	[]	[]	-8	hSpCas9	negative selection	2658585
106201971	106201994	6	+	27260157	HT1080	viability	CCTTCAGGATCAATAGCAGAAGG	ATG5	ENSG00000057663	0.090057043085071	[]	[]	1	hSpCas9	negative selection	2659919
106201956	106201979	6	+	27260157	HT1080	viability	TTGCTGATTGTATTACCTTCAGG	ATG5	ENSG00000057663	-0.66079359330248	[]	[]	-8	hSpCas9	negative selection	2660312
106202044	106202067	6	-	27260157	HT1080	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.11962847586628	[]	[]	-8	hSpCas9	negative selection	2662041
106308363	106308386	6	-	27260157	HT1080	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.389524656872873	[]	[]	3	hSpCas9	negative selection	2681403
106202028	106202051	6	+	27260157	HT1080	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.25787764941536	[]	[]	8	hSpCas9	negative selection	2685239
106186535	106186558	6	+	27260157	HT1080	viability	ATCCTTCAATCTGTTGGCTGTGG	ATG5	ENSG00000057663	1.68035121644364	[]	[]	9	hSpCas9	negative selection	2685308
106316168	106316191	6	-	27260157	HT1080	viability	GTGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	-0.059239657391725	[]	[]	0	hSpCas9	negative selection	2685803
106202016	106202039	6	-	27260157	HT1080	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.0442178838464345	[]	[]	0	hSpCas9	negative selection	2690428
106186598	106186621	6	+	27260157	HT1080	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.655513015629353	[]	[]	-8	hSpCas9	negative selection	2692092
106186613	106186636	6	+	27260157	HT1080	viability	TGCAGAGGTGTTTCCAACATTGG	ATG5	ENSG00000057663	-0.954103194950316	[]	[]	-8	hSpCas9	negative selection	2695610
106293077	106293100	6	+	27260157	HT1080	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.760746239650676	[]	[]	6	hSpCas9	negative selection	2699787
106186584	106186607	6	-	27260157	HT1080	viability	GAGTGAACATCTGAGCTACCCGG	ATG5	ENSG00000057663	0.727332903767931	[]	[]	6	hSpCas9	negative selection	2699838
106279784	106279807	6	+	27260157	HT1080	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.716468694870402	[]	[]	6	hSpCas9	negative selection	2700339
106293032	106293055	6	+	27260157	HT1080	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.760144024374458	[]	[]	-8	hSpCas9	negative selection	2722348
106248203	106248226	6	-	27260157	HT1080	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.250950654453551	[]	[]	2	hSpCas9	negative selection	2724713
106186537	106186560	6	-	27260157	HT1080	viability	TCCCACAGCCAACAGATTGAAGG	ATG5	ENSG00000057663	0.611827766522295	[]	[]	5	hSpCas9	negative selection	2725226
106293049	106293072	6	-	27260157	MKN45	viability	CATCAAGTTCAGCTCTTCCTTGG	ATG5	ENSG00000057663	1.021307715389	[]	[]	8	hSpCas9	negative selection	2730891
106202034	106202057	6	-	27260157	MKN45	viability	TTTCGTCCTGTGGCTGCAGATGG	ATG5	ENSG00000057663	-0.892610477152448	[]	[]	-7	hSpCas9	negative selection	2733309
106186609	106186632	6	-	27260157	MKN45	viability	TGTTGGAAACACCTCTGCAGTGG	ATG5	ENSG00000057663	-0.110422039987983	[]	[]	0	hSpCas9	negative selection	2734715
106201971	106201994	6	+	27260157	MKN45	viability	CCTTCAGGATCAATAGCAGAAGG	ATG5	ENSG00000057663	0.348863759546635	[]	[]	6	hSpCas9	negative selection	2736049
106201956	106201979	6	+	27260157	MKN45	viability	TTGCTGATTGTATTACCTTCAGG	ATG5	ENSG00000057663	-0.533396942151098	[]	[]	-6	hSpCas9	negative selection	2736442
106202044	106202067	6	-	27260157	MKN45	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.840499047409729	[]	[]	8	hSpCas9	negative selection	2738171
106308363	106308386	6	-	27260157	MKN45	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.0237064776020653	[]	[]	0	hSpCas9	negative selection	2757533
106202028	106202051	6	+	27260157	MKN45	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.412735729127236	[]	[]	6	hSpCas9	negative selection	2761369
106186535	106186558	6	+	27260157	MKN45	viability	ATCCTTCAATCTGTTGGCTGTGG	ATG5	ENSG00000057663	1.34272740254287	[]	[]	9	hSpCas9	negative selection	2761438
106316168	106316191	6	-	27260157	MKN45	viability	GTGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.00202042785494711	[]	[]	0	hSpCas9	negative selection	2761933
106202016	106202039	6	-	27260157	MKN45	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.888741861070192	[]	[]	8	hSpCas9	negative selection	2766558
106186598	106186621	6	+	27260157	MKN45	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.761977078398122	[]	[]	-7	hSpCas9	negative selection	2768222
106186613	106186636	6	+	27260157	MKN45	viability	TGCAGAGGTGTTTCCAACATTGG	ATG5	ENSG00000057663	0.0784239727495525	[]	[]	0	hSpCas9	negative selection	2771740
106293077	106293100	6	+	27260157	MKN45	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.556251224416467	[]	[]	7	hSpCas9	negative selection	2775917
106186584	106186607	6	-	27260157	MKN45	viability	GAGTGAACATCTGAGCTACCCGG	ATG5	ENSG00000057663	1.22762591133664	[]	[]	9	hSpCas9	negative selection	2775968
106279784	106279807	6	+	27260157	MKN45	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.197394156488154	[]	[]	5	hSpCas9	negative selection	2776469
106293032	106293055	6	+	27260157	MKN45	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.104220196685353	[]	[]	0	hSpCas9	negative selection	2798478
106248203	106248226	6	-	27260157	MKN45	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.387955538451737	[]	[]	6	hSpCas9	negative selection	2800843
106186537	106186560	6	-	27260157	MKN45	viability	TCCCACAGCCAACAGATTGAAGG	ATG5	ENSG00000057663	0.177233782402863	[]	[]	5	hSpCas9	negative selection	2801356
106293049	106293072	6	-	27260157	RKO	viability	CATCAAGTTCAGCTCTTCCTTGG	ATG5	ENSG00000057663	0.956900559951623	[]	[]	8	hSpCas9	negative selection	2807021
106202034	106202057	6	-	27260157	RKO	viability	TTTCGTCCTGTGGCTGCAGATGG	ATG5	ENSG00000057663	-1.01328779857277	[]	[]	-8	hSpCas9	negative selection	2809439
106186609	106186632	6	-	27260157	RKO	viability	TGTTGGAAACACCTCTGCAGTGG	ATG5	ENSG00000057663	-0.122429980864464	[]	[]	0	hSpCas9	negative selection	2810845
106201971	106201994	6	+	27260157	RKO	viability	CCTTCAGGATCAATAGCAGAAGG	ATG5	ENSG00000057663	0.0139342795056107	[]	[]	0	hSpCas9	negative selection	2812179
106201956	106201979	6	+	27260157	RKO	viability	TTGCTGATTGTATTACCTTCAGG	ATG5	ENSG00000057663	0.324786062321847	[]	[]	1	hSpCas9	negative selection	2812572
106202044	106202067	6	-	27260157	RKO	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.56708586300024	[]	[]	-9	hSpCas9	negative selection	2814301
106308363	106308386	6	-	27260157	RKO	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.378971553484001	[]	[]	2	hSpCas9	negative selection	2833663
106202028	106202051	6	+	27260157	RKO	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.27505827036118	[]	[]	9	hSpCas9	negative selection	2837499
106186535	106186558	6	+	27260157	RKO	viability	ATCCTTCAATCTGTTGGCTGTGG	ATG5	ENSG00000057663	0.0366626178174184	[]	[]	0	hSpCas9	negative selection	2837568
106316168	106316191	6	-	27260157	RKO	viability	GTGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	-0.0491608556291891	[]	[]	0	hSpCas9	negative selection	2838063
106202016	106202039	6	-	27260157	RKO	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.294371059290613	[]	[]	-6	hSpCas9	negative selection	2842688
106186598	106186621	6	+	27260157	RKO	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.0968315891602745	[]	[]	0	hSpCas9	negative selection	2844352
106186613	106186636	6	+	27260157	RKO	viability	TGCAGAGGTGTTTCCAACATTGG	ATG5	ENSG00000057663	0.127738478012968	[]	[]	0	hSpCas9	negative selection	2847870
106293077	106293100	6	+	27260157	RKO	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.0733840902628578	[]	[]	0	hSpCas9	negative selection	2852047
106186584	106186607	6	-	27260157	RKO	viability	GAGTGAACATCTGAGCTACCCGG	ATG5	ENSG00000057663	1.32955445777824	[]	[]	9	hSpCas9	negative selection	2852098
106279784	106279807	6	+	27260157	RKO	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.511904342969968	[]	[]	2	hSpCas9	negative selection	2852599
106293032	106293055	6	+	27260157	RKO	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.312823007997585	[]	[]	-6	hSpCas9	negative selection	2874608
106248203	106248226	6	-	27260157	RKO	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.555794341118965	[]	[]	3	hSpCas9	negative selection	2876973
106186537	106186560	6	-	27260157	RKO	viability	TCCCACAGCCAACAGATTGAAGG	ATG5	ENSG00000057663	0.058975589324856	[]	[]	0	hSpCas9	negative selection	2877486
106293049	106293072	6	-	27260157	SF268	viability	CATCAAGTTCAGCTCTTCCTTGG	ATG5	ENSG00000057663	0.664864852000489	[]	[]	8	hSpCas9	negative selection	2883151
106202034	106202057	6	-	27260157	SF268	viability	TTTCGTCCTGTGGCTGCAGATGG	ATG5	ENSG00000057663	-0.171668884957963	[]	[]	-1	hSpCas9	negative selection	2885569
106186609	106186632	6	-	27260157	SF268	viability	TGTTGGAAACACCTCTGCAGTGG	ATG5	ENSG00000057663	-0.102693946732311	[]	[]	-1	hSpCas9	negative selection	2886975
106201971	106201994	6	+	27260157	SF268	viability	CCTTCAGGATCAATAGCAGAAGG	ATG5	ENSG00000057663	0.50378273734577	[]	[]	7	hSpCas9	negative selection	2888309
106201956	106201979	6	+	27260157	SF268	viability	TTGCTGATTGTATTACCTTCAGG	ATG5	ENSG00000057663	-0.544670012589546	[]	[]	-4	hSpCas9	negative selection	2888702
106202044	106202067	6	-	27260157	SF268	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.455941653147377	[]	[]	7	hSpCas9	negative selection	2890431
106308363	106308386	6	-	27260157	SF268	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.395863015273137	[]	[]	-3	hSpCas9	negative selection	2909793
106202028	106202051	6	+	27260157	SF268	viability	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.6613070068602	[]	[]	9	hSpCas9	negative selection	2913629
106186535	106186558	6	+	27260157	SF268	viability	ATCCTTCAATCTGTTGGCTGTGG	ATG5	ENSG00000057663	0.95532944871297	[]	[]	9	hSpCas9	negative selection	2913698
106316168	106316191	6	-	27260157	SF268	viability	GTGCTTCGAGATGTGTGGTTTGG	ATG5	ENSG00000057663	0.00263787823173171	[]	[]	0	hSpCas9	negative selection	2914193
106202016	106202039	6	-	27260157	SF268	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.219276373462417	[]	[]	3	hSpCas9	negative selection	2918818
106186598	106186621	6	+	27260157	SF268	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.24659501839087	[]	[]	-2	hSpCas9	negative selection	2920482
106186613	106186636	6	+	27260157	SF268	viability	TGCAGAGGTGTTTCCAACATTGG	ATG5	ENSG00000057663	-0.110931134705551	[]	[]	-1	hSpCas9	negative selection	2924000
106293077	106293100	6	+	27260157	SF268	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.566229471539824	[]	[]	8	hSpCas9	negative selection	2928177
106186584	106186607	6	-	27260157	SF268	viability	GAGTGAACATCTGAGCTACCCGG	ATG5	ENSG00000057663	1.55727261227033	[]	[]	9	hSpCas9	negative selection	2928228
106279784	106279807	6	+	27260157	SF268	viability	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.263924016549273	[]	[]	4	hSpCas9	negative selection	2928729
106293032	106293055	6	+	27260157	SF268	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.124611514999139	[]	[]	-1	hSpCas9	negative selection	2950738
106248203	106248226	6	-	27260157	SF268	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.904080784092722	[]	[]	9	hSpCas9	negative selection	2953103
106186537	106186560	6	-	27260157	SF268	viability	TCCCACAGCCAACAGATTGAAGG	ATG5	ENSG00000057663	1.31614850775252	[]	[]	9	hSpCas9	negative selection	2953616
106293033	106293056	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.47458705311912397	[3,4]	[4,0]	-6	hSpCas9	positive selection	2972213
106293078	106293101	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.09779184159170806	[5,5]	[5,4]	2	hSpCas9	positive selection	2972214
106279785	106279808	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.06948137358740615	[3,3]	[3,2]	1	hSpCas9	positive selection	2972215
106279660	106279683	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	-0.38606399478430015	[3,3]	[2,1]	-5	hSpCas9	positive selection	2972216
106293033	106293056	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.1338576339974261	[3,3]	[2,1]	-2	hSpCas9	positive selection	3040071
106293078	106293101	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.1447692525750301	[5,5]	[5,3]	2	hSpCas9	positive selection	3040072
106279785	106279808	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.03944689500359645	[3,3]	[2,2]	0	hSpCas9	positive selection	3040073
106279660	106279683	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	0.10792844778147326	[3,3]	[2,2]	2	hSpCas9	positive selection	3040074
106316136	106316159		-	24336571	A375	resistance to PLX after 7 days	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.22614061734353036	[7,7]	[8,7]	6	hSpCas9	positive selection	3135526
106316138	106316161		+	24336571	A375	resistance to PLX after 7 days	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.1197575459198087	[7,6]	[7,7]	4	hSpCas9	positive selection	3135536
106248201	106248224		+	24336571	A375	resistance to PLX after 7 days	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.06099993178820562	[12,15]	[13,14]	2	hSpCas9	positive selection	3135547
106316136	106316159		-	24336571	A375	resistance to PLX after 14 days	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.2534845561874304	[2,7]	[2,2]	2	hSpCas9	positive selection	3193319
106316138	106316161		+	24336571	A375	resistance to PLX after 14 days	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.03167291248403048	[6,12]	[3,4]	0	hSpCas9	positive selection	3193329
106248201	106248224		+	24336571	A375	resistance to PLX after 14 days	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.8677068796440732	[14,16]	[3,2]	-8	hSpCas9	positive selection	3193340
106316136	106316159		-	24336571	A375	viability after 7 days	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	-0.3687440631430873	[10]	[7,7]	-5	hSpCas9	negative selection	3251112
106316138	106316161		+	24336571	A375	viability after 7 days	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.790555616869237	[13]	[7,6]	-8	hSpCas9	negative selection	3251122
106248201	106248224		+	24336571	A375	viability after 7 days	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.7471667709642968	[8]	[12,15]	9	hSpCas9	negative selection	3251133
106316136	106316159		-	24336571	A375	viability after 14 days	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	-0.7182453953611075	[10]	[2,7]	-7	hSpCas9	negative selection	3308905
106316138	106316161		+	24336571	A375	viability after 14 days	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.4119150211514742	[13]	[6,12]	-5	hSpCas9	negative selection	3308915
106248201	106248224		+	24336571	A375	viability after 14 days	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.9030803249015751	[8]	[14,16]	9	hSpCas9	negative selection	3308926
106316136	106316159	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	-0.07429330642010612	[172,148]	[0,0]	0	hSpCas9	positive selection	3337957
106248201	106248224	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.7329445422753557	[99,83]	[0,0]	3	hSpCas9	positive selection	3337958
106316138	106316161	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.12253081682612	[145,134]	[0,0]	0	hSpCas9	positive selection	3337959
106293032	106293055	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-6.163124681677816e-05	[152,152]	[0,0]	0	hSpCas9	positive selection	3357210
106308458	106308481	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	0.14880175466766601	[137,137]	[0,0]	0	hSpCas9	positive selection	3357211
106293077	106293100	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	2.5328123583258852	[422,422]	[15,15]	8	hSpCas9	positive selection	3357212
106293032	106293055	6	+	26780180	HT29	viability (Avana library 4 designs)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	1.75343458966098	[]	[]	6	hSpCas9	negative selection	3408352
106293077	106293100	6	+	26780180	HT29	viability (Avana library 4 designs)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.789552030254802	[]	[]	-9	hSpCas9	negative selection	3408353
106279784	106279807	6	+	26780180	HT29	viability (Avana library 4 designs)	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	1.82618864011668	[]	[]	7	hSpCas9	negative selection	3408354
106279660	106279683	6	-	26780180	HT29	viability (Avana library 4 designs)	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	0.600198508110922	[]	[]	2	hSpCas9	negative selection	3408355
106293077	106293100	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-13.4883622008962	[]	[]	-8	hSpCas9	negative selection	3481849
106279784	106279807	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	3.43196031805433	[]	[]	5	hSpCas9	negative selection	3481850
106293032	106293055	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-2.08604646183842	[]	[]	-3	hSpCas9	negative selection	3481851
106279660	106279683	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	0.905523292539919	[]	[]	1	hSpCas9	negative selection	3481852
106279784	106279807	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTCTGCACTGTCCATCTAAGG	ATG5	ENSG00000057663	4.01551352514099	[]	[]	6	hSpCas9	negative selection	3481853
106279771	106279794	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	1.11072265667416	[]	[]	1	hSpCas9	negative selection	3481854
106293077	106293100	6	+	26780180	A375	viability (Avana lentiGuide)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-1.90849595063024	[]	[]	-3	hSpCas9	negative selection	3590508
106279784	106279807	6	+	26780180	A375	viability (Avana lentiGuide)	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-6.8582462837477	[]	[]	-9	hSpCas9	negative selection	3590509
106293032	106293055	6	+	26780180	A375	viability (Avana lentiGuide)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-5.013440245378	[]	[]	-8	hSpCas9	negative selection	3590510
106279660	106279683	6	-	26780180	A375	viability (Avana lentiGuide)	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	-7.26741094583361	[]	[]	-9	hSpCas9	negative selection	3590511
106279784	106279807	6	-	26780180	A375	viability (Avana lentiGuide)	CCTTCTGCACTGTCCATCTAAGG	ATG5	ENSG00000057663	-6.25165712817258	[]	[]	-9	hSpCas9	negative selection	3590512
106279771	106279794	6	+	26780180	A375	viability (Avana lentiGuide)	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-6.44608610536607	[]	[]	-9	hSpCas9	negative selection	3590513
106293077	106293100	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.6027252416576349	[9]	[6,4]	-7	hSpCas9	positive selection	3699167
106279784	106279807	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.26676119997937203	[4]	[5,5]	7	hSpCas9	positive selection	3699168
106293032	106293055	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.1524706304122994	[6]	[6,4]	-2	hSpCas9	positive selection	3699169
106279660	106279683	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	-0.07542062061359894	[4]	[5,3]	-1	hSpCas9	positive selection	3699170
106279784	106279807	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTCTGCACTGTCCATCTAAGG	ATG5	ENSG00000057663	0.5329924932623674	[5]	[7,7]	9	hSpCas9	positive selection	3699171
106279771	106279794	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.0909212917520496	[5]	[4,4]	-1	hSpCas9	positive selection	3699172
106293077	106293100	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.36419119095855257	[7]	[7,7]	9	hSpCas9	positive selection	3807774
106279784	106279807	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-0.432033445436195	[5]	[2,3]	-5	hSpCas9	positive selection	3807775
106293032	106293055	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.03853844244089799	[5]	[5,3]	0	hSpCas9	positive selection	3807776
106279660	106279683	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCTGGATGGGATTGCAAAATGG	ATG5	ENSG00000057663	0.4960646838986016	[4]	[6,5]	9	hSpCas9	positive selection	3807777
106279784	106279807	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTCTGCACTGTCCATCTAAGG	ATG5	ENSG00000057663	0.28295278888056885	[5]	[5,5]	7	hSpCas9	positive selection	3807778
106279771	106279794	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.3709990317295582	[5]	[6,5]	9	hSpCas9	positive selection	3807779
106293032	106293055	6	+	26780180	A375	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.563770695803162	[]	[]	1	hSpCas9	negative selection	3916023
106316136	106316159	6	-	26780180	A375	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.98035507066099	[]	[]	4	hSpCas9	negative selection	3916024
106308458	106308481	6	-	26780180	A375	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	1.13735659162291	[]	[]	6	hSpCas9	negative selection	3916025
106293077	106293100	6	+	26780180	A375	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.225713091570981	[]	[]	-6	hSpCas9	negative selection	3916026
106316138	106316161	6	+	26780180	A375	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	1.42949325992601	[]	[]	8	hSpCas9	negative selection	3916027
106248201	106248224	6	+	26780180	A375	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	1.5323057454552	[]	[]	8	hSpCas9	negative selection	3916028
106293032	106293055	6	+	26780180	HT29	viability (GeCKOv2 library)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.94537994875736	[]	[]	4	hSpCas9	negative selection	4023989
106316136	106316159	6	-	26780180	HT29	viability (GeCKOv2 library)	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	1.34343493975452	[]	[]	6	hSpCas9	negative selection	4023990
106308458	106308481	6	-	26780180	HT29	viability (GeCKOv2 library)	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	2.06101878001488	[]	[]	9	hSpCas9	negative selection	4023991
106293077	106293100	6	+	26780180	HT29	viability (GeCKOv2 library)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.550650827028105	[]	[]	1	hSpCas9	negative selection	4023992
106316138	106316161	6	+	26780180	HT29	viability (GeCKOv2 library)	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.981527539043951	[]	[]	4	hSpCas9	negative selection	4023993
106248201	106248224	6	+	26780180	HT29	viability (GeCKOv2 library)	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	1.89201286886483	[]	[]	9	hSpCas9	negative selection	4023994
106316136	106316159	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.23419786417466104	[1]	[0,1]	6	hSpCas9	positive selection	4160474
106316138	106316161	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.2261757880458489	[3]	[1,1]	-5	hSpCas9	positive selection	4160484
106248201	106248224	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.006379050545957304	[3]	[2,1]	0	hSpCas9	positive selection	4160495
106316136	106316159	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	-0.5228246140455652	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4224496
106316138	106316161	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.9187792112364793	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4224506
106248201	106248224	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.007098690613463798	[2]	[0,0,3,0]	0	hSpCas9	positive selection	4224517
106316136	106316159	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.33700800442966056	[3]	[3,3]	6	hSpCas9	positive selection	4257201
106248201	106248224	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.1949887540306628	[2]	[2,1]	-4	hSpCas9	positive selection	4257202
106316138	106316161	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.0004918206106329093	[3]	[3,1]	0	hSpCas9	positive selection	4257203
106293032	106293055	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.06449912137668114	[2]	[3,0]	-1	hSpCas9	positive selection	4321485
106308458	106308481	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.41013070840929355	[3]	[3,0]	-7	hSpCas9	positive selection	4321486
106293077	106293100	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.17777750660396074	[3]	[4,2]	3	hSpCas9	positive selection	4321487
106202016	106202038	6	-	27760321	OCIAML3	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.37149611771259744	[439,336]	[281,530]	4	hSpCas9	negative selection	4380304
106248147	106248169	6	+	27760321	OCIAML3	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-0.948255138094841	[2,1]	[0,0]	-7	hSpCas9	negative selection	4380305
106248213	106248235	6	+	27760321	OCIAML3	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.03476359957784056	[468,353]	[219,430]	0	hSpCas9	negative selection	4380306
106279672	106279694	6	-	27760321	OCIAML3	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.18781850456413712	[445,343]	[194,365]	-2	hSpCas9	negative selection	4380307
106279772	106279794	6	+	27760321	OCIAML3	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.4933174476188288	[253,199]	[67,199]	-5	hSpCas9	negative selection	4380308
106293078	106293100	6	+	27760321	OCIAML3	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.6768959316986836	[128,81]	[29,77]	-6	hSpCas9	negative selection	4380309
106202016	106202038	6	-	27760321	OCIAML2	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.3825294420502974	[439,336]	[340,492]	5	hSpCas9	negative selection	4463767
106248147	106248169	6	+	27760321	OCIAML2	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-0.9970005033598897	[2,1]	[0,0]	-7	hSpCas9	negative selection	4463768
106248213	106248235	6	+	27760321	OCIAML2	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.3567708989411136	[468,353]	[348,519]	5	hSpCas9	negative selection	4463769
106279672	106279694	6	-	27760321	OCIAML2	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.698682034564936	[445,343]	[172,224]	-6	hSpCas9	negative selection	4463770
106279772	106279794	6	+	27760321	OCIAML2	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.6914012564792643	[253,199]	[115,108]	-6	hSpCas9	negative selection	4463771
106293078	106293100	6	+	27760321	OCIAML2	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3750197993482842	[128,81]	[105,112]	5	hSpCas9	negative selection	4463772
106202016	106202038	6	-	27760321	MV411	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.23912913967470822	[439,336]	[169,283]	-2	hSpCas9	negative selection	4547230
106248147	106248169	6	+	27760321	MV411	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-0.703176569180159	[2,1]	[0,0]	-5	hSpCas9	negative selection	4547231
106248213	106248235	6	+	27760321	MV411	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.2407725265443661	[468,353]	[141,356]	-2	hSpCas9	negative selection	4547232
106279672	106279694	6	-	27760321	MV411	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.7046640473415118	[445,343]	[119,216]	-5	hSpCas9	negative selection	4547233
106279772	106279794	6	+	27760321	MV411	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.7371293484564776	[253,199]	[335,115]	5	hSpCas9	negative selection	4547234
106293078	106293100	6	+	27760321	MV411	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.7312376626655246	[128,81]	[160,42]	5	hSpCas9	negative selection	4547235
106202016	106202038	6	-	27760321	HL60	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.7196072215853407	[439,336]	[406,636]	8	hSpCas9	negative selection	4630693
106248147	106248169	6	+	27760321	HL60	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	0.545467340117491	[2,1]	[0,4]	6	hSpCas9	negative selection	4630694
106248213	106248235	6	+	27760321	HL60	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.02710174520029919	[468,353]	[263,419]	0	hSpCas9	negative selection	4630695
106279672	106279694	6	-	27760321	HL60	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.5519162218201272	[445,343]	[217,218]	-5	hSpCas9	negative selection	4630696
106279772	106279794	6	+	27760321	HL60	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.3101471539801327	[253,199]	[208,248]	4	hSpCas9	negative selection	4630697
106293078	106293100	6	+	27760321	HL60	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.7279502836697951	[128,81]	[176,101]	8	hSpCas9	negative selection	4630698
106202016	106202038	6	-	27760321	HT1080	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.36795813341182204	[336,262]	[136,43]	-2	hSpCas9	negative selection	4714156
106248147	106248169	6	+	27760321	HT1080	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	0.30562769391905587	[1,1]	[0,0]	1	hSpCas9	negative selection	4714157
106248213	106248235	6	+	27760321	HT1080	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.5563008733882486	[353,275]	[7,169]	-2	hSpCas9	negative selection	4714158
106279672	106279694	6	-	27760321	HT1080	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.258294592372377	[343,268]	[30,72]	-5	hSpCas9	negative selection	4714159
106279772	106279794	6	+	27760321	HT1080	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.9120242085173882	[199,155]	[30,44]	-4	hSpCas9	negative selection	4714160
106293078	106293100	6	+	27760321	HT1080	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-4.86201028105493	[81,63]	[0,0]	-8	hSpCas9	negative selection	4714161
106202016	106202038	6	-	27760321	HT29	viability after 7 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.2858416338054199	[336,262]	[444,350,605]	4	hSpCas9	negative selection	4797619
106248147	106248169	6	+	27760321	HT29	viability after 7 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.3840325596302083	[1,1]	[0,0,0]	-9	hSpCas9	negative selection	4797620
106248213	106248235	6	+	27760321	HT29	viability after 7 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.8443679012417008	[353,275]	[823,511,853]	9	hSpCas9	negative selection	4797621
106279672	106279694	6	-	27760321	HT29	viability after 7 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	0.16277993015490982	[343,268]	[655,301,396]	2	hSpCas9	negative selection	4797622
106279772	106279794	6	+	27760321	HT29	viability after 7 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.1307454999488985	[199,155]	[223,319,204]	2	hSpCas9	negative selection	4797623
106293078	106293100	6	+	27760321	HT29	viability after 7 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.13598767872438922	[81,63]	[142,88,33]	-2	hSpCas9	negative selection	4797624
106202016	106202038	6	-	27760321	HT29	viability after 25 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.16443315254714097	[336,262]	[417,364,364]	1	hSpCas9	negative selection	4881082
106248147	106248169	6	+	27760321	HT29	viability after 25 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.214054570927468	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	4881083
106248213	106248235	6	+	27760321	HT29	viability after 25 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.0067935586139820925	[353,275]	[307,364,420]	0	hSpCas9	negative selection	4881084
106279672	106279694	6	-	27760321	HT29	viability after 25 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.4102525741589953	[343,268]	[247,179,374]	-4	hSpCas9	negative selection	4881085
106279772	106279794	6	+	27760321	HT29	viability after 25 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.3827369578389189	[199,155]	[386,191,201]	4	hSpCas9	negative selection	4881086
106293078	106293100	6	+	27760321	HT29	viability after 25 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.15279542311197591	[81,63]	[94,63,121]	1	hSpCas9	negative selection	4881087
106202016	106202038	6	-	27760321	HT29	viability after 22 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.41046689127875124	[336,262]	[737,422,211]	4	hSpCas9	negative selection	4964545
106248147	106248169	6	+	27760321	HT29	viability after 22 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.2313732027867275	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	4964546
106248213	106248235	6	+	27760321	HT29	viability after 22 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.277287158596074	[353,275]	[479,487,353]	3	hSpCas9	negative selection	4964547
106279672	106279694	6	-	27760321	HT29	viability after 22 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.2014997530160563	[343,268]	[125,184,151]	-7	hSpCas9	negative selection	4964548
106279772	106279794	6	+	27760321	HT29	viability after 22 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.32852025176068456	[199,155]	[261,260,251]	3	hSpCas9	negative selection	4964549
106293078	106293100	6	+	27760321	HT29	viability after 22 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.4908177764167414	[81,63]	[27,95,56]	-4	hSpCas9	negative selection	4964550
106202016	106202038	6	-	27760321	HT29	viability after 19 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.32920852317600563	[336,262]	[337,671,278]	3	hSpCas9	negative selection	5048008
106248147	106248169	6	+	27760321	HT29	viability after 19 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.2155331503635143	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	5048009
106248213	106248235	6	+	27760321	HT29	viability after 19 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.2498038733011304	[353,275]	[577,524,205]	2	hSpCas9	negative selection	5048010
106279672	106279694	6	-	27760321	HT29	viability after 19 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.7833827760915696	[343,268]	[279,83,252]	-6	hSpCas9	negative selection	5048011
106279772	106279794	6	+	27760321	HT29	viability after 19 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.9473716970989766	[199,155]	[392,433,351]	8	hSpCas9	negative selection	5048012
106293078	106293100	6	+	27760321	HT29	viability after 19 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.39788973782152826	[81,63]	[146,81,104]	4	hSpCas9	negative selection	5048013
106202016	106202038	6	-	27760321	HT29	viability after 16 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.2929050547633655	[336,262]	[350,442,432]	3	hSpCas9	negative selection	5131471
106248147	106248169	6	+	27760321	HT29	viability after 16 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.1840686979425925	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	5131472
106248213	106248235	6	+	27760321	HT29	viability after 16 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.20986562669911632	[353,275]	[487,202,242]	-2	hSpCas9	negative selection	5131473
106279672	106279694	6	-	27760321	HT29	viability after 16 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.7330208816790423	[343,268]	[277,119,229]	-6	hSpCas9	negative selection	5131474
106279772	106279794	6	+	27760321	HT29	viability after 16 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.6223183583078382	[199,155]	[192,530,178]	7	hSpCas9	negative selection	5131475
106293078	106293100	6	+	27760321	HT29	viability after 16 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.34941802508155684	[81,63]	[79,94,17]	-4	hSpCas9	negative selection	5131476
106202016	106202038	6	-	27760321	HT29	viability after 13 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.25086930286002646	[336,262]	[417,387,434]	3	hSpCas9	negative selection	5214934
106248147	106248169	6	+	27760321	HT29	viability after 13 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.2363560973867305	[1,1]	[0,0,0]	-8	hSpCas9	negative selection	5214935
106248213	106248235	6	+	27760321	HT29	viability after 13 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	0.6801608582547161	[353,275]	[836,506,421]	8	hSpCas9	negative selection	5214936
106279672	106279694	6	-	27760321	HT29	viability after 13 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.08576714864476984	[343,268]	[295,317,387]	-1	hSpCas9	negative selection	5214937
106279772	106279794	6	+	27760321	HT29	viability after 13 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.13986652914918662	[199,155]	[178,384,124]	1	hSpCas9	negative selection	5214938
106293078	106293100	6	+	27760321	HT29	viability after 13 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.8090639060226168	[81,63]	[76,146,216]	9	hSpCas9	negative selection	5214939
106202016	106202038	6	-	27760321	HT29	viability after 10 days	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.1768489686960374	[336,262]	[394,552,327]	2	hSpCas9	negative selection	5298397
106248147	106248169	6	+	27760321	HT29	viability after 10 days	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-1.3423674045470744	[1,1]	[0,0,0]	-8	hSpCas9	negative selection	5298398
106248213	106248235	6	+	27760321	HT29	viability after 10 days	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.9192561511931863	[353,275]	[273,241,110]	-7	hSpCas9	negative selection	5298399
106279672	106279694	6	-	27760321	HT29	viability after 10 days	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.03238522857928802	[343,268]	[414,222,477]	0	hSpCas9	negative selection	5298400
106279772	106279794	6	+	27760321	HT29	viability after 10 days	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.1768996021956426	[199,155]	[294,217,79]	-2	hSpCas9	negative selection	5298401
106293078	106293100	6	+	27760321	HT29	viability after 10 days	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3460749239290888	[81,63]	[81,59,201]	5	hSpCas9	negative selection	5298402
106202016	106202038	6	-	27760321	MOLM13	viability	ATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.5789631805709149	[439,336]	[143,146]	-4	hSpCas9	negative selection	5381860
106248147	106248169	6	+	27760321	MOLM13	viability	TACCTGATATATTCTAAAGGGG	ATG5	ENSG00000057663	-0.47711975635256376	[2,1]	[0,0]	-3	hSpCas9	negative selection	5381861
106248213	106248235	6	+	27760321	MOLM13	viability	CCGATTGATGGCCCAAAACTGG	ATG5	ENSG00000057663	-0.6410717618475663	[468,353]	[232,74]	-4	hSpCas9	negative selection	5381862
106279672	106279694	6	-	27760321	MOLM13	viability	ATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-2.2742838662961153	[445,343]	[8,76]	-8	hSpCas9	negative selection	5381863
106279772	106279794	6	+	27760321	MOLM13	viability	CTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-1.854968403189913	[253,199]	[52,19]	-7	hSpCas9	negative selection	5381864
106293078	106293100	6	+	27760321	MOLM13	viability	GATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-1.9701483257146784	[128,81]	[1,25]	-8	hSpCas9	negative selection	5381865
106325581	106325604	6	+	27661255	K562	viability	GATTCCGCGCTCCGGTGGGGCGG	ATG5	ENSG00000057663	-0.02756018275342484	[784,978]	[715,664]	-1	dCas9-KRAB	negative selection	5464027
106325439	106325462	6	-	27661255	K562	viability	GTAGGTGTGGTAGGAAGGAGGGG	ATG5	ENSG00000057663	0.373050506128247	[1679,1662]	[1803,1665]	9	dCas9-KRAB	negative selection	5464028
106316136	106316159	6	-	27260156	BXPC3	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.2109776808239573	[733]	[881,861,806,1011]	4	hSpCas9	negative selection	5529661
106248201	106248224	6	+	27260156	BXPC3	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.21040335056341278	[405]	[363,310,342,461]	-5	hSpCas9	negative selection	5529662
106316138	106316161	6	+	27260156	BXPC3	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.05806002524522291	[796]	[936,789,873,858]	1	hSpCas9	negative selection	5529663
106293032	106293055	6	+	27260156	BXPC3	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.15013544798516867	[365]	[357,373,445,542]	3	hSpCas9	negative selection	5593945
106308458	106308481	6	-	27260156	BXPC3	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.05302737616252831	[568]	[631,556,605,477]	-1	hSpCas9	negative selection	5593946
106293077	106293100	6	+	27260156	BXPC3	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.2278431729606175	[882]	[988,927,1103,1348]	5	hSpCas9	negative selection	5593947
106316136	106316159	6	-	27260156	A673	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.18063766578463603	[733]	[1029,1002,955,1008]	4	hSpCas9	negative selection	5650912
106248201	106248224	6	+	27260156	A673	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.15415738517519048	[405]	[614,396,367,390]	-4	hSpCas9	negative selection	5650913
106316138	106316161	6	+	27260156	A673	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.009813555042665678	[796]	[1060,823,908,1079]	0	hSpCas9	negative selection	5650914
106293032	106293055	6	+	27260156	A673	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.26373117029578186	[365]	[617,429,505,570]	6	hSpCas9	negative selection	5715196
106308458	106308481	6	-	27260156	A673	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3152863517770898	[568]	[622,465,491,629]	-7	hSpCas9	negative selection	5715197
106293077	106293100	6	+	27260156	A673	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.05687083808645965	[882]	[1266,968,915,949]	-1	hSpCas9	negative selection	5715198
106316136	106316159	6	-	27260156	A375	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.5479344651505689	[733]	[1028,1709,1147,1190]	7	hSpCas9	negative selection	5772163
106248201	106248224	6	+	27260156	A375	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.10947285054802794	[405]	[414,461,364,508]	-1	hSpCas9	negative selection	5772164
106316138	106316161	6	+	27260156	A375	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.3262674401916995	[796]	[1195,1461,1109,961]	5	hSpCas9	negative selection	5772165
106293032	106293055	6	+	27260156	A375	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.35392990732678703	[365]	[432,585,530,627]	5	hSpCas9	negative selection	5836447
106308458	106308481	6	-	27260156	A375	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	0.09474070525881667	[568]	[720,760,861,521]	1	hSpCas9	negative selection	5836448
106293077	106293100	6	+	27260156	A375	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.19260441136412776	[882]	[1040,1558,1141,1036]	2	hSpCas9	negative selection	5836449
106316136	106316159	6	-	27260156	COLO741	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	-0.004845274908809816	[733]	[1023,970,822]	0	hSpCas9	negative selection	5893414
106248201	106248224	6	+	27260156	COLO741	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.8141918600707573	[405]	[366,264,260]	-9	hSpCas9	negative selection	5893415
106316138	106316161	6	+	27260156	COLO741	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.018520060868476573	[796]	[1127,1044,861]	0	hSpCas9	negative selection	5893416
106293032	106293055	6	+	27260156	COLO741	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.011211433957298178	[365]	[436,515,457]	0	hSpCas9	negative selection	5957698
106308458	106308481	6	-	27260156	COLO741	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.07068307508856969	[568]	[630,925,525]	-1	hSpCas9	negative selection	5957699
106293077	106293100	6	+	27260156	COLO741	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.010472303294952967	[882]	[1094,1229,1036]	0	hSpCas9	negative selection	5957700
106316136	106316159	6	-	27260156	CAL120	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.42658893871599823	[733]	[1417,1119,1173]	6	hSpCas9	negative selection	6014665
106248201	106248224	6	+	27260156	CAL120	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.5597267221283604	[405]	[212,362,430]	-7	hSpCas9	negative selection	6014666
106316138	106316161	6	+	27260156	CAL120	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.05794332367290833	[796]	[1006,1164,922]	0	hSpCas9	negative selection	6014667
106293032	106293055	6	+	27260156	CAL120	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.2475813741863034	[365]	[583,479,563]	3	hSpCas9	negative selection	6078949
106308458	106308481	6	-	27260156	CAL120	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.20813737772810156	[568]	[589,682,562]	-3	hSpCas9	negative selection	6078950
106293077	106293100	6	+	27260156	CAL120	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.18416258487474846	[882]	[1262,1185,1296]	2	hSpCas9	negative selection	6078951
106316136	106316159	6	-	27260156	CADOES1	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.5947193224871239	[733]	[956,1340,735,1092]	8	hSpCas9	negative selection	6135916
106248201	106248224	6	+	27260156	CADOES1	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.2202403387377513	[405]	[297,386,281,329]	-4	hSpCas9	negative selection	6135917
106316138	106316161	6	+	27260156	CADOES1	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.23138769206901433	[796]	[948,753,814,965]	4	hSpCas9	negative selection	6135918
106293032	106293055	6	+	27260156	CADOES1	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.01628575504878127	[365]	[331,315,317,381]	0	hSpCas9	negative selection	6200200
106308458	106308481	6	-	27260156	CADOES1	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.24647068346364806	[568]	[499,312,548,420]	-4	hSpCas9	negative selection	6200201
106293077	106293100	6	+	27260156	CADOES1	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.13939753571666913	[882]	[963,907,868,875]	2	hSpCas9	negative selection	6200202
106316136	106316159	6	-	27260156	EWS502	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3583810939081604	[733]	[702,1024,1110,1193]	6	hSpCas9	negative selection	6257167
106248201	106248224	6	+	27260156	EWS502	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.4416822284510018	[405]	[254,225,411,389]	-6	hSpCas9	negative selection	6257168
106316138	106316161	6	+	27260156	EWS502	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.0022347955212375092	[796]	[1112,866,678,659]	0	hSpCas9	negative selection	6257169
106293032	106293055	6	+	27260156	EWS502	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.08632474255885819	[365]	[418,476,299,445]	1	hSpCas9	negative selection	6321451
106308458	106308481	6	-	27260156	EWS502	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.34616833337117064	[568]	[453,390,468,594]	-5	hSpCas9	negative selection	6321452
106293077	106293100	6	+	27260156	EWS502	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3454863823983979	[882]	[901,1076,1626,1187]	6	hSpCas9	negative selection	6321453
106316136	106316159	6	-	27260156	EW8	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.14343131651109575	[733]	[817,740,446,673]	2	hSpCas9	negative selection	6378418
106248201	106248224	6	+	27260156	EW8	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.1312675995620631	[405]	[338,317,247,308]	-2	hSpCas9	negative selection	6378419
106316138	106316161	6	+	27260156	EW8	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.010478541517113915	[796]	[793,750,557,491]	0	hSpCas9	negative selection	6378420
106293032	106293055	6	+	27260156	EW8	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.2599714344024863	[365]	[427,320,316,367]	5	hSpCas9	negative selection	6442702
106308458	106308481	6	-	27260156	EW8	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3953703838591493	[568]	[447,293,289,389]	-6	hSpCas9	negative selection	6442703
106293077	106293100	6	+	27260156	EW8	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3321408153815749	[882]	[1122,1052,660,829]	6	hSpCas9	negative selection	6442704
106316136	106316159	6	-	27260156	CORL105	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3479235091266847	[733]	[1085,1083,1224,999]	6	hSpCas9	negative selection	6499669
106248201	106248224	6	+	27260156	CORL105	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.1533445641548963	[405]	[425,285,661,374]	-3	hSpCas9	negative selection	6499670
106316138	106316161	6	+	27260156	CORL105	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.09394207243794628	[796]	[1160,769,1034,1032]	1	hSpCas9	negative selection	6499671
106293032	106293055	6	+	27260156	CORL105	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.05945578129726847	[365]	[412,444,567,377]	1	hSpCas9	negative selection	6563953
106308458	106308481	6	-	27260156	CORL105	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.5524415608644777	[568]	[392,408,522,500]	-7	hSpCas9	negative selection	6563954
106293077	106293100	6	+	27260156	CORL105	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.32321215408019055	[882]	[1330,1260,1332,1255]	6	hSpCas9	negative selection	6563955
106316136	106316159	6	-	27260156	HS294T	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.30427701311105293	[733]	[261,358,336,470]	4	hSpCas9	negative selection	6620920
106248201	106248224	6	+	27260156	HS294T	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.2131084217206771	[405]	[189,125,65,157]	-3	hSpCas9	negative selection	6620921
106316138	106316161	6	+	27260156	HS294T	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.33558115601302696	[796]	[260,508,270,547]	4	hSpCas9	negative selection	6620922
106293032	106293055	6	+	27260156	HS294T	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.15450699152453728	[365]	[107,145,139,112]	-2	hSpCas9	negative selection	6685204
106308458	106308481	6	-	27260156	HS294T	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.10512354120901132	[568]	[274,122,152,273]	-1	hSpCas9	negative selection	6685205
106293077	106293100	6	+	27260156	HS294T	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.36580073369692057	[882]	[514,332,459,447]	5	hSpCas9	negative selection	6685206
106316136	106316159	6	-	27260156	HCC44	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.20907459959954433	[733]	[1022,800,1038,1007]	3	hSpCas9	negative selection	6742171
106248201	106248224	6	+	27260156	HCC44	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.2830318049897407	[405]	[310,266,516,442]	-4	hSpCas9	negative selection	6742172
106316138	106316161	6	+	27260156	HCC44	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.08247392133482401	[796]	[979,853,1120,901]	1	hSpCas9	negative selection	6742173
106293032	106293055	6	+	27260156	HCC44	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.19111586149207935	[365]	[449,615,338,436]	3	hSpCas9	negative selection	6806455
106308458	106308481	6	-	27260156	HCC44	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.30795713198553226	[568]	[516,493,531,536]	-5	hSpCas9	negative selection	6806456
106293077	106293100	6	+	27260156	HCC44	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.10907173307562201	[882]	[1299,962,1288,828]	1	hSpCas9	negative selection	6806457
106316136	106316159	6	-	27260156	G402	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.7297588328245634	[733]	[1754,1514,2025,717]	8	hSpCas9	negative selection	6863422
106248201	106248224	6	+	27260156	G402	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.31652216953760026	[405]	[316,523,1347,245]	4	hSpCas9	negative selection	6863423
106316138	106316161	6	+	27260156	G402	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.2714887705146328	[796]	[1254,1395,985,1082]	3	hSpCas9	negative selection	6863424
106293032	106293055	6	+	27260156	G402	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.08523520991495476	[365]	[494,306,639,445]	1	hSpCas9	negative selection	6927706
106308458	106308481	6	-	27260156	G402	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	0.2047646998185661	[568]	[826,625,697,1028]	2	hSpCas9	negative selection	6927707
106293077	106293100	6	+	27260156	G402	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.40959969816428654	[882]	[1289,1780,1553,1109]	5	hSpCas9	negative selection	6927708
106316136	106316159	6	-	27260156	L33	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.1577843121687561	[733]	[781,402,513,693]	3	hSpCas9	negative selection	6984673
106248201	106248224	6	+	27260156	L33	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.7867003510780031	[405]	[180,98,193,211]	-9	hSpCas9	negative selection	6984674
106316138	106316161	6	+	27260156	L33	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.028297368647705823	[796]	[673,322,592,848]	0	hSpCas9	negative selection	6984675
106293032	106293055	6	+	27260156	L33	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.0907063198528737	[365]	[461,171,194,364]	2	hSpCas9	negative selection	7048957
106308458	106308481	6	-	27260156	L33	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3131541407320705	[568]	[501,164,269,495]	-6	hSpCas9	negative selection	7048958
106293077	106293100	6	+	27260156	L33	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.11130356138448338	[882]	[858,362,642,1048]	2	hSpCas9	negative selection	7048959
106316136	106316159	6	-	27260156	K562	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.18268631432428273	[733]	[644,918,814,593]	2	hSpCas9	negative selection	7105924
106248201	106248224	6	+	27260156	K562	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.1558051931185825	[405]	[263,506,371,171]	-2	hSpCas9	negative selection	7105925
106316138	106316161	6	+	27260156	K562	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.08369082125436134	[796]	[772,783,479,646]	-1	hSpCas9	negative selection	7105926
106293032	106293055	6	+	27260156	K562	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.054188813326902785	[365]	[449,329,235,339]	0	hSpCas9	negative selection	7170208
106308458	106308481	6	-	27260156	K562	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.27419847730499464	[568]	[453,495,340,387]	-3	hSpCas9	negative selection	7170209
106293077	106293100	6	+	27260156	K562	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.5852524868607444	[882]	[1031,1180,1315,1158]	7	hSpCas9	negative selection	7170210
106316136	106316159	6	-	27260156	HT29	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.2845950390187256	[733]	[1246,973,1060,1062]	5	hSpCas9	negative selection	7227175
106248201	106248224	6	+	27260156	HT29	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.17548554242988093	[405]	[640,542,689,378]	3	hSpCas9	negative selection	7227176
106316138	106316161	6	+	27260156	HT29	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.1554102229754809	[796]	[1002,1075,819,631]	-3	hSpCas9	negative selection	7227177
106293032	106293055	6	+	27260156	HT29	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.021757832452289017	[365]	[613,551,372,303]	0	hSpCas9	negative selection	7291459
106308458	106308481	6	-	27260156	HT29	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.09753923742717074	[568]	[690,753,593,564]	-2	hSpCas9	negative selection	7291460
106293077	106293100	6	+	27260156	HT29	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.21753557033252335	[882]	[1137,1333,1323,1192]	4	hSpCas9	negative selection	7291461
106316136	106316159	6	-	27260156	MHHES1	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.23196627308108642	[733]	[990,984,1011,894]	4	hSpCas9	negative selection	7348426
106248201	106248224	6	+	27260156	MHHES1	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.043756941322932424	[405]	[736,525,306,365]	0	hSpCas9	negative selection	7348427
106316138	106316161	6	+	27260156	MHHES1	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.17836984397308076	[796]	[793,703,905,751]	-3	hSpCas9	negative selection	7348428
106293032	106293055	6	+	27260156	MHHES1	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.014911404267351602	[365]	[251,671,408,345]	0	hSpCas9	negative selection	7412710
106308458	106308481	6	-	27260156	MHHES1	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.1696864678591281	[568]	[680,422,497,643]	-3	hSpCas9	negative selection	7412711
106293077	106293100	6	+	27260156	MHHES1	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.1666718369360437	[882]	[1386,1490,1139,611]	3	hSpCas9	negative selection	7412712
106316136	106316159	6	-	27260156	MEWO	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.05250965086931103	[733]	[756,711,675]	1	hSpCas9	negative selection	7469677
106248201	106248224	6	+	27260156	MEWO	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.06558798573632083	[405]	[395,401,296]	-1	hSpCas9	negative selection	7469678
106316138	106316161	6	+	27260156	MEWO	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.1516846206645044	[796]	[899,640,516]	-3	hSpCas9	negative selection	7469679
106293032	106293055	6	+	27260156	MEWO	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.1906667024441845	[365]	[280,365,248]	-4	hSpCas9	negative selection	7533961
106308458	106308481	6	-	27260156	MEWO	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.41308874810263607	[568]	[484,356,373]	-7	hSpCas9	negative selection	7533962
106293077	106293100	6	+	27260156	MEWO	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.16608864173146443	[882]	[867,768,596]	-4	hSpCas9	negative selection	7533963
106316136	106316159	6	-	27260156	LNCAPCLONEFGC	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3936045515734867	[733]	[1002,695,984,834]	6	hSpCas9	negative selection	7590928
106248201	106248224	6	+	27260156	LNCAPCLONEFGC	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.026224000654788693	[405]	[241,450,308,430]	0	hSpCas9	negative selection	7590929
106316138	106316161	6	+	27260156	LNCAPCLONEFGC	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.39826994343299604	[796]	[902,768,1312,886]	6	hSpCas9	negative selection	7590930
106293032	106293055	6	+	27260156	LNCAPCLONEFGC	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.16311366683481732	[365]	[231,237,401,332]	-3	hSpCas9	negative selection	7655212
106308458	106308481	6	-	27260156	LNCAPCLONEFGC	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.39594517121329836	[568]	[393,401,479,302]	-6	hSpCas9	negative selection	7655213
106293077	106293100	6	+	27260156	LNCAPCLONEFGC	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.26882054054116644	[882]	[938,779,917,1222]	4	hSpCas9	negative selection	7655214
106316136	106316159	6	-	27260156	PANC0327	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.013814003870331382	[733]	[746,522,802,584]	0	hSpCas9	negative selection	7712179
106248201	106248224	6	+	27260156	PANC0327	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.5378713598758749	[405]	[286,262,293,150]	-6	hSpCas9	negative selection	7712180
106316138	106316161	6	+	27260156	PANC0327	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.014186006462266088	[796]	[838,354,779,885]	0	hSpCas9	negative selection	7712181
106293032	106293055	6	+	27260156	PANC0327	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.03486915081298925	[365]	[325,260,390,362]	0	hSpCas9	negative selection	7776463
106308458	106308481	6	-	27260156	PANC0327	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.2515183143799307	[568]	[388,325,461,530]	-4	hSpCas9	negative selection	7776464
106293077	106293100	6	+	27260156	PANC0327	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.32729243302825106	[882]	[1417,620,1136,842]	5	hSpCas9	negative selection	7776465
106316136	106316159	6	-	27260156	NCIH2009	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.19281768280984102	[733]	[1176,1195,1141]	2	hSpCas9	negative selection	7833430
106248201	106248224	6	+	27260156	NCIH2009	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.03714568274141533	[405]	[774,541,466]	0	hSpCas9	negative selection	7833431
106316138	106316161	6	+	27260156	NCIH2009	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.2223851021046963	[796]	[932,762,1164]	-3	hSpCas9	negative selection	7833432
106293032	106293055	6	+	27260156	NCIH2009	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.08699614933337485	[365]	[476,511,626]	1	hSpCas9	negative selection	7897714
106308458	106308481	6	-	27260156	NCIH2009	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.4899453314473712	[568]	[771,397,570]	-6	hSpCas9	negative selection	7897715
106293077	106293100	6	+	27260156	NCIH2009	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.4941848764975557	[882]	[1895,1703,1641]	6	hSpCas9	negative selection	7897716
106316136	106316159	6	-	27260156	NCIH1373	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.4516455105292585	[733]	[815,1461,786,358]	4	hSpCas9	negative selection	7954681
106248201	106248224	6	+	27260156	NCIH1373	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.06173080932892003	[405]	[411,216,243,284]	0	hSpCas9	negative selection	7954682
106316138	106316161	6	+	27260156	NCIH1373	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.44114056216163144	[796]	[1533,909,1058,378]	4	hSpCas9	negative selection	7954683
106293032	106293055	6	+	27260156	NCIH1373	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.046564820751781366	[365]	[449,344,244,150]	0	hSpCas9	negative selection	8018965
106308458	106308481	6	-	27260156	NCIH1373	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.3500359635365142	[568]	[736,288,452,153]	-3	hSpCas9	negative selection	8018966
106293077	106293100	6	+	27260156	NCIH1373	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.9365537171651298	[882]	[2746,1866,1820,322]	8	hSpCas9	negative selection	8018967
106316136	106316159	6	-	27260156	PATU8902	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.7867069398243312	[733]	[2188,1158,1968,1647]	8	hSpCas9	negative selection	8075932
106248201	106248224	6	+	27260156	PATU8902	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	0.06544260994352694	[405]	[792,399,742,354]	0	hSpCas9	negative selection	8075933
106316138	106316161	6	+	27260156	PATU8902	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.39124138457792135	[796]	[1229,1787,1568,1163]	4	hSpCas9	negative selection	8075934
106293032	106293055	6	+	27260156	PATU8902	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.3379734316273213	[365]	[866,494,454,821]	3	hSpCas9	negative selection	8140216
106308458	106308481	6	-	27260156	PATU8902	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.4567289453952509	[568]	[402,438,741,693]	-4	hSpCas9	negative selection	8140217
106293077	106293100	6	+	27260156	PATU8902	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.47228335944005584	[882]	[1737,1819,2001,1100]	5	hSpCas9	negative selection	8140218
106316136	106316159	6	-	27260156	PANC1	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.2992319020571049	[733]	[729,1037,656,726]	5	hSpCas9	negative selection	8197183
106248201	106248224	6	+	27260156	PANC1	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.20888908141383108	[405]	[395,336,277,210]	-3	hSpCas9	negative selection	8197184
106316138	106316161	6	+	27260156	PANC1	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.2369055807677518	[796]	[879,927,778,671]	4	hSpCas9	negative selection	8197185
106293032	106293055	6	+	27260156	PANC1	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.057646289316382215	[365]	[336,262,270,319]	-1	hSpCas9	negative selection	8261467
106308458	106308481	6	-	27260156	PANC1	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.4398647975630334	[568]	[369,387,379,310]	-6	hSpCas9	negative selection	8261468
106293077	106293100	6	+	27260156	PANC1	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3412044090387042	[882]	[938,1325,746,898]	5	hSpCas9	negative selection	8261469
106316136	106316159	6	-	27260156	PANC0813	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3646682041871998	[733]	[1441,985,782,1248]	6	hSpCas9	negative selection	8318434
106248201	106248224	6	+	27260156	PANC0813	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.33192656667178966	[405]	[405,351,286,466]	-5	hSpCas9	negative selection	8318435
106316138	106316161	6	+	27260156	PANC0813	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.1411498328770011	[796]	[820,1192,985,1103]	2	hSpCas9	negative selection	8318436
106293032	106293055	6	+	27260156	PANC0813	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.18662067332802162	[365]	[766,509,322,386]	3	hSpCas9	negative selection	8382718
106308458	106308481	6	-	27260156	PANC0813	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.1915042676737865	[568]	[832,441,557,532]	-3	hSpCas9	negative selection	8382719
106293077	106293100	6	+	27260156	PANC0813	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.2758891296077689	[882]	[1060,1379,1233,1323]	4	hSpCas9	negative selection	8382720
106316136	106316159	6	-	27260156	RDES	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3661775487661878	[733]	[992,951,1206,1223]	6	hSpCas9	negative selection	8439685
106248201	106248224	6	+	27260156	RDES	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.17073601018215398	[405]	[367,421,454,410]	-3	hSpCas9	negative selection	8439686
106316138	106316161	6	+	27260156	RDES	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.030484980234977477	[796]	[855,898,995,994]	0	hSpCas9	negative selection	8439687
106293032	106293055	6	+	27260156	RDES	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.2956233653608462	[365]	[419,582,499,568]	5	hSpCas9	negative selection	8503969
106308458	106308481	6	-	27260156	RDES	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.23882351041180236	[568]	[413,548,553,744]	-4	hSpCas9	negative selection	8503970
106293077	106293100	6	+	27260156	RDES	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.3691587316411703	[882]	[1058,1170,1652,1421]	6	hSpCas9	negative selection	8503971
106316136	106316159	6	-	27260156	PC3	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.18811900681020388	[733]	[654,818,1322,700]	4	hSpCas9	negative selection	8560936
106248201	106248224	6	+	27260156	PC3	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.2971607863760637	[405]	[149,342,481,460]	-6	hSpCas9	negative selection	8560937
106316138	106316161	6	+	27260156	PC3	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.04422332030226317	[796]	[604,873,961,890]	1	hSpCas9	negative selection	8560938
106293032	106293055	6	+	27260156	PC3	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.07974032813492038	[365]	[141,326,582,494]	-2	hSpCas9	negative selection	8625220
106308458	106308481	6	-	27260156	PC3	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.32529733832565305	[568]	[242,404,1054,396]	-6	hSpCas9	negative selection	8625221
106293077	106293100	6	+	27260156	PC3	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.023734320791065966	[882]	[479,1009,1344,899]	0	hSpCas9	negative selection	8625222
106316136	106316159	6	-	27260156	PATU8988T	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.13713474978328988	[733]	[795,863,580,898]	2	hSpCas9	negative selection	8682187
106248201	106248224	6	+	27260156	PATU8988T	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.14435086007054407	[405]	[343,210,458,393]	-2	hSpCas9	negative selection	8682188
106316138	106316161	6	+	27260156	PATU8988T	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.15108422319466563	[796]	[833,974,728,898]	2	hSpCas9	negative selection	8682189
106293032	106293055	6	+	27260156	PATU8988T	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.005074714566299765	[365]	[330,296,192,605]	0	hSpCas9	negative selection	8746471
106308458	106308481	6	-	27260156	PATU8988T	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.6186259930154037	[568]	[284,460,310,387]	-7	hSpCas9	negative selection	8746472
106293077	106293100	6	+	27260156	PATU8988T	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.039417977552650085	[882]	[577,833,779,1155]	0	hSpCas9	negative selection	8746473
106316136	106316159	6	-	27260156	T47D	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.23742039816600624	[733]	[1127,979,924,1002]	5	hSpCas9	negative selection	8803438
106248201	106248224	6	+	27260156	T47D	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.06464875560784497	[405]	[482,346,450,539]	-1	hSpCas9	negative selection	8803439
106316138	106316161	6	+	27260156	T47D	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.05891997529969517	[796]	[989,899,866,1123]	1	hSpCas9	negative selection	8803440
106293032	106293055	6	+	27260156	T47D	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.26334600494375815	[365]	[453,448,618,528]	5	hSpCas9	negative selection	8867722
106308458	106308481	6	-	27260156	T47D	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.11842925646409908	[568]	[600,489,781,575]	-3	hSpCas9	negative selection	8867723
106293077	106293100	6	+	27260156	T47D	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.15701583897645566	[882]	[1050,1054,1237,1252]	3	hSpCas9	negative selection	8867724
106316136	106316159	6	-	27260156	SU8686	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.16013185346272296	[733]	[905,804,752,762]	2	hSpCas9	negative selection	8924689
106248201	106248224	6	+	27260156	SU8686	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.09441512171964919	[405]	[362,359,297,506]	-2	hSpCas9	negative selection	8924690
106316138	106316161	6	+	27260156	SU8686	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.8599167184524124	[796]	[517,342,357,535]	-8	hSpCas9	negative selection	8924691
106293032	106293055	6	+	27260156	SU8686	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.9438615143148368	[365]	[184,214,205,135]	-8	hSpCas9	negative selection	8988973
106308458	106308481	6	-	27260156	SU8686	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.7337386395348895	[568]	[259,263,428,438]	-8	hSpCas9	negative selection	8988974
106293077	106293100	6	+	27260156	SU8686	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.29822754048252575	[882]	[738,1158,1187,1274]	5	hSpCas9	negative selection	8988975
106316136	106316159	6	-	27260156	SKES1	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3073553830792849	[733]	[931,1052,882,782]	6	hSpCas9	negative selection	9045940
106248201	106248224	6	+	27260156	SKES1	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.28867337601381904	[405]	[255,468,173,420]	-6	hSpCas9	negative selection	9045941
106316138	106316161	6	+	27260156	SKES1	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.04197162236370411	[796]	[864,1005,631,636]	-1	hSpCas9	negative selection	9045942
106293032	106293055	6	+	27260156	SKES1	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	-0.04798615304707521	[365]	[398,301,468,249]	-1	hSpCas9	negative selection	9110224
106308458	106308481	6	-	27260156	SKES1	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.15482869547740177	[568]	[647,590,363,466]	-3	hSpCas9	negative selection	9110225
106293077	106293100	6	+	27260156	SKES1	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	-0.023825535174115675	[882]	[865,983,797,827]	0	hSpCas9	negative selection	9110226
106316136	106316159	6	-	27260156	TOV112D	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.14561372420438057	[733]	[814,1129,766,622]	3	hSpCas9	negative selection	9167191
106248201	106248224	6	+	27260156	TOV112D	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.3396941248041827	[405]	[470,326,151,347]	-6	hSpCas9	negative selection	9167192
106316138	106316161	6	+	27260156	TOV112D	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.059931369693208336	[796]	[1014,814,632,873]	1	hSpCas9	negative selection	9167193
106293032	106293055	6	+	27260156	TOV112D	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.47373124305217756	[365]	[490,540,728,286]	8	hSpCas9	negative selection	9231475
106308458	106308481	6	-	27260156	TOV112D	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.2153448534759817	[568]	[393,642,321,628]	-4	hSpCas9	negative selection	9231476
106293077	106293100	6	+	27260156	TOV112D	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.17030569424223885	[882]	[1048,1190,1021,775]	3	hSpCas9	negative selection	9231477
106316136	106316159	6	-	27260156	TC71	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.14563947032073166	[733]	[946,765,814,958]	3	hSpCas9	negative selection	9288442
106248201	106248224	6	+	27260156	TC71	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.2339591896617095	[405]	[463,301,302,413]	-6	hSpCas9	negative selection	9288443
106316138	106316161	6	+	27260156	TC71	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	-0.14739276110742772	[796]	[646,707,926,802]	-4	hSpCas9	negative selection	9288444
106293032	106293055	6	+	27260156	TC71	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.1077580449425003	[365]	[449,442,414,379]	2	hSpCas9	negative selection	9352726
106308458	106308481	6	-	27260156	TC71	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.31300586908611794	[568]	[439,458,495,574]	-7	hSpCas9	negative selection	9352727
106293077	106293100	6	+	27260156	TC71	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.022567941973141492	[882]	[961,810,1214,841]	0	hSpCas9	negative selection	9352728
106316136	106316159	6	-	27260156	TC32	viability	AACTTGTTTCACGCTATATCAGG	ATG5	ENSG00000057663	0.3236022406214488	[733]	[786,685,1152,903]	6	hSpCas9	negative selection	9409693
106248201	106248224	6	+	27260156	TC32	viability	TTCCATGAGTTTCCGATTGATGG	ATG5	ENSG00000057663	-0.1074201893466015	[405]	[330,307,371,409]	-2	hSpCas9	negative selection	9409694
106316138	106316161	6	+	27260156	TC32	viability	TGATATAGCGTGAAACAAGTTGG	ATG5	ENSG00000057663	0.16127565652454257	[796]	[524,781,1156,958]	3	hSpCas9	negative selection	9409695
106293032	106293055	6	+	27260156	TC32	viability	AAATGTACTGTGATGTTCCAAGG	ATG5	ENSG00000057663	0.05738221599189086	[365]	[327,257,444,440]	1	hSpCas9	negative selection	9473977
106308458	106308481	6	-	27260156	TC32	viability	AAGAGTAAGTTATTTGACGTTGG	ATG5	ENSG00000057663	-0.11490855591206292	[568]	[448,288,859,496]	-2	hSpCas9	negative selection	9473978
106293077	106293100	6	+	27260156	TC32	viability	AGATCAAATAGCAAACCAATTGG	ATG5	ENSG00000057663	0.28633615835982373	[882]	[983,785,1452,923]	5	hSpCas9	negative selection	9473979
106202028	106202051	6	+	27869803	HPAFII	viability after 27 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	-0.011117468355399174	[110]	[52,61,NaN]	0	hSpCas9	negative selection	9593042
106279784	106279807	6	+	27869803	HPAFII	viability after 27 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	1.4701183855881759	[182]	[229,296,NaN]	9	hSpCas9	negative selection	9593045
106202028	106202051	6	+	27869803	HPAFII	viability after 15 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.42183233924807195	[110]	[99,196,NaN]	5	hSpCas9	negative selection	9675491
106279784	106279807	6	+	27869803	HPAFII	viability after 15 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.5463159157385367	[182]	[449,185,NaN]	6	hSpCas9	negative selection	9675494
106202028	106202051	6	+	27869803	ASPC1	viability after 36 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	-0.8290008393234563	[257]	[69,53,33]	-7	hSpCas9	negative selection	9757940
106279784	106279807	6	+	27869803	ASPC1	viability after 36 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	-0.12335321440592358	[723]	[29,472,179]	-1	hSpCas9	negative selection	9757943
106202028	106202051	6	+	27869803	PATU8988S	viability after 35 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.2950648360399009	[227]	[370,78,NaN]	9	hSpCas9	negative selection	9840389
106279784	106279807	6	+	27869803	PATU8988S	viability after 35 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.7641590906727451	[485]	[303,360,NaN]	7	hSpCas9	negative selection	9840392
106202028	106202051	6	+	27869803	PATU8988S	viability after 31 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	1.2054060544885687	[227]	[250,156,NaN]	9	hSpCas9	negative selection	9922838
106279784	106279807	6	+	27869803	PATU8988S	viability after 31 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	0.6120471750192602	[485]	[260,340,NaN]	7	hSpCas9	negative selection	9922841
106202028	106202051	6	+	27869803	HPAFII	viability after 35 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	-1.3004653035565428	[110]	[3,43,NaN]	-6	hSpCas9	negative selection	10005287
106279784	106279807	6	+	27869803	HPAFII	viability after 35 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	1.2023560520025325	[182]	[112,325,NaN]	7	hSpCas9	negative selection	10005290
106202028	106202051	6	+	27869803	HPAFII	viability after 31 days	AACTGTCCATCTGCAGCCACAGG	ATG5	ENSG00000057663	0.21331038591988893	[110]	[65,78,NaN]	1	hSpCas9	negative selection	10087736
106279784	106279807	6	+	27869803	HPAFII	viability after 31 days	CCTTAGATGGACAGTGCAGAAGG	ATG5	ENSG00000057663	1.2072839655678982	[182]	[150,330,NaN]	8	hSpCas9	negative selection	10087739
106279672	106279695	6	-	28162770	P31FUJ	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	0.11986941390409189	[64]	[82]	1	hSpCas9	negative selection	10115299
106186598	106186621	6	+	28162770	P31FUJ	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.558958422606972	[597]	[476]	-5	hSpCas9	negative selection	10115300
106316173	106316196	6	-	28162770	P31FUJ	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.5388003914238451	[320]	[547]	6	hSpCas9	negative selection	10115301
106308363	106308386	6	-	28162770	P31FUJ	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.12389130863366038	[163]	[209]	1	hSpCas9	negative selection	10115302
106248203	106248226	6	-	28162770	P31FUJ	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.046240077619807224	[238]	[289]	0	hSpCas9	negative selection	10115303
106201987	106202010	6	+	28162770	P31FUJ	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.3008797913630843	[419]	[607]	3	hSpCas9	negative selection	10115304
106201971	106201994	6	-	28162770	P31FUJ	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.5498634337568838	[260]	[448]	6	hSpCas9	negative selection	10115305
106202044	106202067	6	-	28162770	P31FUJ	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.6113138276681083	[51]	[19]	-7	hSpCas9	negative selection	10115306
106202016	106202039	6	-	28162770	P31FUJ	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.06930347213149923	[199]	[223]	0	hSpCas9	negative selection	10115307
106279771	106279794	6	+	28162770	P31FUJ	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.31340789301064986	[653]	[954]	3	hSpCas9	negative selection	10115308
106279672	106279695	6	-	28162770	TF1	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10284665
106186598	106186621	6	+	28162770	TF1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10284666
106316173	106316196	6	-	28162770	TF1	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10284667
106308363	106308386	6	-	28162770	TF1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10284668
106248203	106248226	6	-	28162770	TF1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10284669
106201987	106202010	6	+	28162770	TF1	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10284670
106201971	106201994	6	-	28162770	TF1	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	NaN	[NaN]	[306]	1	hSpCas9	negative selection	10284671
106202044	106202067	6	-	28162770	TF1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10284672
106202016	106202039	6	-	28162770	TF1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10284673
106279771	106279794	6	+	28162770	TF1	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	NaN	[NaN]	[453]	1	hSpCas9	negative selection	10284674
106279672	106279695	6	-	28162770	SKM1	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.6520766965796931	[31]	[35]	-5	hSpCas9	negative selection	10454031
106186598	106186621	6	+	28162770	SKM1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.0817609718229384	[175]	[146]	-7	hSpCas9	negative selection	10454032
106316173	106316196	6	-	28162770	SKM1	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.8143076826993711	[91]	[285]	7	hSpCas9	negative selection	10454033
106308363	106308386	6	-	28162770	SKM1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.04643326463205222	[58]	[100]	0	hSpCas9	negative selection	10454034
106248203	106248226	6	-	28162770	SKM1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10454035
106201987	106202010	6	+	28162770	SKM1	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.2801786967844726	[108]	[233]	2	hSpCas9	negative selection	10454036
106201971	106201994	6	-	28162770	SKM1	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	2.4574911305449603	[68]	[669]	9	hSpCas9	negative selection	10454037
106202044	106202067	6	-	28162770	SKM1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.7629608026991503	[4]	[14]	7	hSpCas9	negative selection	10454038
106202016	106202039	6	-	28162770	SKM1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.7981549560676379	[59]	[60]	-5	hSpCas9	negative selection	10454039
106279771	106279794	6	+	28162770	SKM1	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.6884138493340966	[138]	[395]	6	hSpCas9	negative selection	10454040
106279672	106279695	6	-	28162770	SKM1	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.6520766965796931	[31]	[35]	-5	hSpCas9	negative selection	10623397
106186598	106186621	6	+	28162770	SKM1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.0817609718229384	[175]	[146]	-7	hSpCas9	negative selection	10623398
106316173	106316196	6	-	28162770	SKM1	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.8143076826993711	[91]	[285]	7	hSpCas9	negative selection	10623399
106308363	106308386	6	-	28162770	SKM1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.04643326463205222	[58]	[100]	0	hSpCas9	negative selection	10623400
106248203	106248226	6	-	28162770	SKM1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10623401
106201987	106202010	6	+	28162770	SKM1	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.2801786967844726	[108]	[233]	2	hSpCas9	negative selection	10623402
106201971	106201994	6	-	28162770	SKM1	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	2.4574911305449603	[68]	[669]	9	hSpCas9	negative selection	10623403
106202044	106202067	6	-	28162770	SKM1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.7629608026991503	[4]	[14]	7	hSpCas9	negative selection	10623404
106202016	106202039	6	-	28162770	SKM1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.7981549560676379	[59]	[60]	-5	hSpCas9	negative selection	10623405
106279771	106279794	6	+	28162770	SKM1	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.6884138493340966	[138]	[395]	6	hSpCas9	negative selection	10623406
106279672	106279695	6	-	28162770	PL21	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-2.784753493120472	[94]	[5]	-9	hSpCas9	negative selection	10792763
106186598	106186621	6	+	28162770	PL21	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.6770036377251466	[539]	[146]	-5	hSpCas9	negative selection	10792764
106316173	106316196	6	-	28162770	PL21	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.025092758632089263	[338]	[144]	0	hSpCas9	negative selection	10792765
106308363	106308386	6	-	28162770	PL21	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.3597962804778054	[187]	[104]	3	hSpCas9	negative selection	10792766
106248203	106248226	6	-	28162770	PL21	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	-0.04086848501447482	[233]	[98]	0	hSpCas9	negative selection	10792767
106201987	106202010	6	+	28162770	PL21	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	-0.4703409574178933	[416]	[130]	-3	hSpCas9	negative selection	10792768
106201971	106201994	6	-	28162770	PL21	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	1.126766428159101	[241]	[229]	8	hSpCas9	negative selection	10792769
106202044	106202067	6	-	28162770	PL21	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	0.46317402032311383	[19]	[11]	4	hSpCas9	negative selection	10792770
106202016	106202039	6	-	28162770	PL21	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.765644670172767	[124]	[31]	-5	hSpCas9	negative selection	10792771
106279771	106279794	6	+	28162770	PL21	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.537174601766891	[474]	[299]	5	hSpCas9	negative selection	10792772
106279672	106279695	6	-	28162770	P31FUJ	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	0.11986941390409189	[64]	[82]	1	hSpCas9	negative selection	10962129
106186598	106186621	6	+	28162770	P31FUJ	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.558958422606972	[597]	[476]	-5	hSpCas9	negative selection	10962130
106316173	106316196	6	-	28162770	P31FUJ	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.5388003914238451	[320]	[547]	6	hSpCas9	negative selection	10962131
106308363	106308386	6	-	28162770	P31FUJ	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.12389130863366038	[163]	[209]	1	hSpCas9	negative selection	10962132
106248203	106248226	6	-	28162770	P31FUJ	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.046240077619807224	[238]	[289]	0	hSpCas9	negative selection	10962133
106201987	106202010	6	+	28162770	P31FUJ	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.3008797913630843	[419]	[607]	3	hSpCas9	negative selection	10962134
106201971	106201994	6	-	28162770	P31FUJ	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.5498634337568838	[260]	[448]	6	hSpCas9	negative selection	10962135
106202044	106202067	6	-	28162770	P31FUJ	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.6113138276681083	[51]	[19]	-7	hSpCas9	negative selection	10962136
106202016	106202039	6	-	28162770	P31FUJ	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.06930347213149923	[199]	[223]	0	hSpCas9	negative selection	10962137
106279771	106279794	6	+	28162770	P31FUJ	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.31340789301064986	[653]	[954]	3	hSpCas9	negative selection	10962138
106279672	106279695	6	-	28162770	OCIAML5	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.3781353825315847	[71]	[49]	-7	hSpCas9	negative selection	11131495
106186598	106186621	6	+	28162770	OCIAML5	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.8604788106801968	[343]	[341]	-5	hSpCas9	negative selection	11131496
106316173	106316196	6	-	28162770	OCIAML5	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.09893615726678406	[212]	[358]	0	hSpCas9	negative selection	11131497
106308363	106308386	6	-	28162770	OCIAML5	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.41908048075711635	[132]	[320]	3	hSpCas9	negative selection	11131498
106248203	106248226	6	-	28162770	OCIAML5	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.06006067311066876	[109]	[206]	0	hSpCas9	negative selection	11131499
106201987	106202010	6	+	28162770	OCIAML5	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.16378738033684015	[180]	[365]	1	hSpCas9	negative selection	11131500
106201971	106201994	6	-	28162770	OCIAML5	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.39798828881055137	[213]	[508]	3	hSpCas9	negative selection	11131501
106202044	106202067	6	-	28162770	OCIAML5	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-0.007344796341907989	[48]	[87]	0	hSpCas9	negative selection	11131502
106202016	106202039	6	-	28162770	OCIAML5	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.19156036153626102	[113]	[234]	1	hSpCas9	negative selection	11131503
106279771	106279794	6	+	28162770	OCIAML5	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.44738812347769086	[426]	[1050]	4	hSpCas9	negative selection	11131504
106279672	106279695	6	-	28162770	EOL1	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.3233797418730513	[132]	[55]	-2	hSpCas9	negative selection	11300861
106186598	106186621	6	+	28162770	EOL1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.7106004863188387	[701]	[112]	-8	hSpCas9	negative selection	11300862
106316173	106316196	6	-	28162770	EOL1	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.8985950758940675	[616]	[605]	7	hSpCas9	negative selection	11300863
106308363	106308386	6	-	28162770	EOL1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.023790108606972726	[383]	[198]	0	hSpCas9	negative selection	11300864
106248203	106248226	6	-	28162770	EOL1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.4364468101019673	[323]	[230]	4	hSpCas9	negative selection	11300865
106201987	106202010	6	+	28162770	EOL1	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.5861035895399075	[592]	[468]	5	hSpCas9	negative selection	11300866
106201971	106201994	6	-	28162770	EOL1	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	-0.16856163282094686	[383]	[179]	-1	hSpCas9	negative selection	11300867
106202044	106202067	6	-	28162770	EOL1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-0.2598767995668929	[24]	[10]	-2	hSpCas9	negative selection	11300868
106202016	106202039	6	-	28162770	EOL1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	1.3092116218058596	[215]	[281]	9	hSpCas9	negative selection	11300869
106279771	106279794	6	+	28162770	EOL1	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.7351498141546347	[633]	[555]	6	hSpCas9	negative selection	11300870
106279672	106279695	6	-	28162770	MOLM13	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.0514847775490006	[128]	[44]	-5	hSpCas9	negative selection	11470227
106186598	106186621	6	+	28162770	MOLM13	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-2.930825812432332	[790]	[74]	-8	hSpCas9	negative selection	11470228
106316173	106316196	6	-	28162770	MOLM13	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.3659663566276327	[466]	[261]	-2	hSpCas9	negative selection	11470229
106308363	106308386	6	-	28162770	MOLM13	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.7858672107012044	[402]	[168]	-4	hSpCas9	negative selection	11470230
106248203	106248226	6	-	28162770	MOLM13	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	-0.20596616876698898	[409]	[256]	-1	hSpCas9	negative selection	11470231
106201987	106202010	6	+	28162770	MOLM13	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.04467795082003456	[589]	[439]	0	hSpCas9	negative selection	11470232
106201971	106201994	6	-	28162770	MOLM13	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	-0.4876359893148163	[542]	[279]	-3	hSpCas9	negative selection	11470233
106202044	106202067	6	-	28162770	MOLM13	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.934209062026767	[36]	[6]	-7	hSpCas9	negative selection	11470234
106202016	106202039	6	-	28162770	MOLM13	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.4379884410908711	[177]	[94]	-3	hSpCas9	negative selection	11470235
106279771	106279794	6	+	28162770	MOLM13	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.6872602672173351	[1019]	[457]	-4	hSpCas9	negative selection	11470236
106279672	106279695	6	-	28162770	HEL	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-4.215242163127215	[144]	[4]	-9	hSpCas9	negative selection	11639593
106186598	106186621	6	+	28162770	HEL	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.6291222656003908	[622]	[128]	-7	hSpCas9	negative selection	11639594
106316173	106316196	6	-	28162770	HEL	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.7438422212292588	[501]	[191]	-5	hSpCas9	negative selection	11639595
106308363	106308386	6	-	28162770	HEL	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.4936473339752101	[274]	[247]	4	hSpCas9	negative selection	11639596
106248203	106248226	6	-	28162770	HEL	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.43099365486341756	[314]	[271]	3	hSpCas9	negative selection	11639597
106201987	106202010	6	+	28162770	HEL	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.14141437794990663	[510]	[360]	1	hSpCas9	negative selection	11639598
106201971	106201994	6	-	28162770	HEL	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	-0.23802203178350784	[382]	[207]	-2	hSpCas9	negative selection	11639599
106202044	106202067	6	-	28162770	HEL	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-2.5588950291692933	[45]	[4]	-8	hSpCas9	negative selection	11639600
106202016	106202039	6	-	28162770	HEL	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.18110421284581613	[153]	[86]	-1	hSpCas9	negative selection	11639601
106279771	106279794	6	+	28162770	HEL	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	-0.09484185279161883	[781]	[468]	0	hSpCas9	negative selection	11639602
106279672	106279695	6	-	28162770	MV411	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.0184565091902589	[100]	[41]	-6	hSpCas9	negative selection	11808959
106186598	106186621	6	+	28162770	MV411	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.47963729386178366	[532]	[321]	-4	hSpCas9	negative selection	11808960
106316173	106316196	6	-	28162770	MV411	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.44757716527209557	[335]	[385]	4	hSpCas9	negative selection	11808961
106308363	106308386	6	-	28162770	MV411	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.10121680993173146	[165]	[149]	0	hSpCas9	negative selection	11808962
106248203	106248226	6	-	28162770	MV411	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.4181079384679096	[214]	[241]	4	hSpCas9	negative selection	11808963
106201987	106202010	6	+	28162770	MV411	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.642500350300353	[399]	[525]	6	hSpCas9	negative selection	11808964
106201971	106201994	6	-	28162770	MV411	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.46479438222192493	[245]	[285]	4	hSpCas9	negative selection	11808965
106202044	106202067	6	-	28162770	MV411	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	2.0775125493404625	[8]	[31]	9	hSpCas9	negative selection	11808966
106202016	106202039	6	-	28162770	MV411	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.379685349081215	[124]	[136]	3	hSpCas9	negative selection	11808967
106279771	106279794	6	+	28162770	MV411	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.44952045331338564	[418]	[481]	4	hSpCas9	negative selection	11808968
106279672	106279695	6	-	28162770	MONOMAC1	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-0.518964941946916	[54]	[43]	-4	hSpCas9	negative selection	11978325
106186598	106186621	6	+	28162770	MONOMAC1	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	0.524895932149178	[327]	[540]	5	hSpCas9	negative selection	11978326
106316173	106316196	6	-	28162770	MONOMAC1	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.1866674454144983	[255]	[333]	2	hSpCas9	negative selection	11978327
106308363	106308386	6	-	28162770	MONOMAC1	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	0.9543277444760306	[112]	[250]	8	hSpCas9	negative selection	11978328
106248203	106248226	6	-	28162770	MONOMAC1	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.0527414620719735	[163]	[194]	0	hSpCas9	negative selection	11978329
106201987	106202010	6	+	28162770	MONOMAC1	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.5148377661438219	[231]	[379]	5	hSpCas9	negative selection	11978330
106201971	106201994	6	-	28162770	MONOMAC1	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.6687778055460492	[151]	[276]	6	hSpCas9	negative selection	11978331
106202044	106202067	6	-	28162770	MONOMAC1	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-1.7819993477807095	[20]	[6]	-8	hSpCas9	negative selection	11978332
106202016	106202039	6	-	28162770	MONOMAC1	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.19703684705955382	[83]	[83]	-2	hSpCas9	negative selection	11978333
106279771	106279794	6	+	28162770	MONOMAC1	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.14400007077551313	[254]	[322]	1	hSpCas9	negative selection	11978334
106279672	106279695	6	-	28162770	OCIAML2	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.4706298252421615	[12]	[25]	-7	hSpCas9	negative selection	12147691
106186598	106186621	6	+	28162770	OCIAML2	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-1.1142383207865771	[90]	[232]	-6	hSpCas9	negative selection	12147692
106316173	106316196	6	-	28162770	OCIAML2	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	-0.09211820198843135	[59]	[311]	-1	hSpCas9	negative selection	12147693
106308363	106308386	6	-	28162770	OCIAML2	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.7544227912427524	[48]	[160]	-5	hSpCas9	negative selection	12147694
106248203	106248226	6	-	28162770	OCIAML2	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	-0.08816018841974807	[41]	[218]	0	hSpCas9	negative selection	12147695
106201987	106202010	6	+	28162770	OCIAML2	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	1.0679939608121252	[57]	[673]	8	hSpCas9	negative selection	12147696
106201971	106201994	6	-	28162770	OCIAML2	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	1.3172727341492705	[31]	[441]	9	hSpCas9	negative selection	12147697
106202044	106202067	6	-	28162770	OCIAML2	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	-2.7925579201295236	[4]	[3]	-9	hSpCas9	negative selection	12147698
106202016	106202039	6	-	28162770	OCIAML2	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	-0.4135988802057823	[30]	[128]	-3	hSpCas9	negative selection	12147699
106279771	106279794	6	+	28162770	OCIAML2	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.4655550771603951	[103]	[795]	4	hSpCas9	negative selection	12147700
106279672	106279695	6	-	28162770	OCIAML3	viability	GATCACAAGCAACTCTGGATGGG	ATG5	ENSG00000057663	-1.2836675197120129	[24]	[30]	-7	hSpCas9	negative selection	12317057
106186598	106186621	6	+	28162770	OCIAML3	viability	TGTTCACTCAGCCACTGCAGAGG	ATG5	ENSG00000057663	-0.07943446749440497	[111]	[319]	0	hSpCas9	negative selection	12317058
106316173	106316196	6	-	28162770	OCIAML3	viability	AAGATGTGCTTCGAGATGTGTGG	ATG5	ENSG00000057663	0.36018867006271227	[95]	[371]	3	hSpCas9	negative selection	12317059
106308363	106308386	6	-	28162770	OCIAML3	viability	ATGAAGGCACACCACTGAAATGG	ATG5	ENSG00000057663	-0.7595937060421382	[82]	[147]	-5	hSpCas9	negative selection	12317060
106248203	106248226	6	-	28162770	OCIAML3	viability	GGCCATCAATCGGAAACTCATGG	ATG5	ENSG00000057663	0.156540926114968	[73]	[248]	1	hSpCas9	negative selection	12317061
106201987	106202010	6	+	28162770	OCIAML3	viability	CAGAAGGACAAACTTCTTTGAGG	ATG5	ENSG00000057663	0.8581768405145409	[126]	[694]	7	hSpCas9	negative selection	12317062
106201971	106201994	6	-	28162770	OCIAML3	viability	CCTTCTGCTATTGATCCTGAAGG	ATG5	ENSG00000057663	0.2969684659209819	[78]	[292]	3	hSpCas9	negative selection	12317063
106202044	106202067	6	-	28162770	OCIAML3	viability	TCAGAAGCTGTTTCGTCCTGTGG	ATG5	ENSG00000057663	1.3128829552843555	[5]	[44]	9	hSpCas9	negative selection	12317064
106202016	106202039	6	-	28162770	OCIAML3	viability	GATGGACAGTTGCACACACTAGG	ATG5	ENSG00000057663	0.03402358228887892	[32]	[101]	0	hSpCas9	negative selection	12317065
106279771	106279794	6	+	28162770	OCIAML3	viability	GCTTCAATTGCATCCTTAGATGG	ATG5	ENSG00000057663	0.5241737860241509	[163]	[711]	5	hSpCas9	negative selection	12317066