Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 146227
• Symbol: BEAN1
• Description: brain expressed associated with NEDD4 1

DataSource: http://genomecrispr.dkfz.de/#!/results/BEAN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66469720	66469743	16	-	26627737	DLD1	viability	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	-0.6527434415585793	[939]	[175,231,158]	-6	hSpCas9	negative selection	794708
66469737	66469760	16	+	26627737	DLD1	viability	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-1.2160112989326604	[790]	[167,21,122]	-8	hSpCas9	negative selection	794709
66469720	66469743	16	-	26627737	GBM cells	viability after 5 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.25038624538706344	[434]	[280,273]	4	hSpCas9	negative selection	877023
66469737	66469760	16	+	26627737	GBM cells	viability after 5 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.010888316142736082	[278]	[174,121]	0	hSpCas9	negative selection	877024
66469720	66469743	16	-	26627737	GBM cells	viability after 13 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.22448707773687848	[434]	[272,277]	3	hSpCas9	negative selection	959338
66469737	66469760	16	+	26627737	GBM cells	viability after 13 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.44226041403269445	[278]	[106,114]	-5	hSpCas9	negative selection	959339
66469720	66469743	16	-	26627737	GBM cells	viability after 21 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.4623678294359518	[434]	[369,284]	5	hSpCas9	negative selection	1041653
66469737	66469760	16	+	26627737	GBM cells	viability after 21 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.1751694373066447	[278]	[151,117]	-2	hSpCas9	negative selection	1041654
66469720	66469743	16	-	26627737	RPE1	viability after 9 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	2.732825249394411	[196]	[433,378]	9	hSpCas9	negative selection	1123968
66469737	66469760	16	+	26627737	RPE1	viability after 9 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-1.250619615760709	[1278]	[121,227]	-7	hSpCas9	negative selection	1123969
66469720	66469743	16	-	26627737	RPE1	viability after 12 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	2.9278771283940666	[196]	[479,320]	9	hSpCas9	negative selection	1206283
66469737	66469760	16	+	26627737	RPE1	viability after 12 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.6510318310251906	[1278]	[144,296]	-4	hSpCas9	negative selection	1206284
66469720	66469743	16	-	26627737	RPE1	viability after 15 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	2.8070441066112557	[196]	[445,335]	9	hSpCas9	negative selection	1288598
66469737	66469760	16	+	26627737	RPE1	viability after 15 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.5010037545931428	[1278]	[246,263]	-3	hSpCas9	negative selection	1288599
66469720	66469743	16	-	26627737	RPE1	viability after 18 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	2.4539478178690897	[196]	[226,359]	9	hSpCas9	negative selection	1370913
66469737	66469760	16	+	26627737	RPE1	viability after 18 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.4643910831298966	[1278]	[254,244]	-3	hSpCas9	negative selection	1370914
66469720	66469743	16	-	26627737	HeLa	viability after 8 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.5782927335508778	[728]	[549,403,482]	5	hSpCas9	negative selection	1453228
66469737	66469760	16	+	26627737	HeLa	viability after 8 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.096153271578086	[132]	[159,107,111]	8	hSpCas9	negative selection	1453229
66469720	66469743	16	-	26627737	HeLa	viability after 12 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.3381987056083475	[728]	[455,472,205]	3	hSpCas9	negative selection	1535543
66469737	66469760	16	+	26627737	HeLa	viability after 12 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.1789737624526855	[132]	[56,61,258]	8	hSpCas9	negative selection	1535544
66469720	66469743	16	-	26627737	HeLa	viability after 15 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	-0.27823578543108163	[728]	[253,247,230]	-2	hSpCas9	negative selection	1617858
66469737	66469760	16	+	26627737	HeLa	viability after 15 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.1458172607593664	[132]	[91,96,174]	7	hSpCas9	negative selection	1617859
66469720	66469743	16	-	26627737	HeLa	viability after 18 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	-0.2987045050396172	[728]	[167,199,230]	-3	hSpCas9	negative selection	1700173
66469737	66469760	16	+	26627737	HeLa	viability after 18 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.1946085928538452	[132]	[65,84,174]	8	hSpCas9	negative selection	1700174
66469720	66469743	16	-	26627737	HCT116	viability after 6 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.3087461080516	[648]	[146,114]	1	hSpCas9	negative selection	1782488
66469737	66469760	16	+	26627737	HCT116	viability after 6 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-1.3892428902236145	[1131]	[36,84]	-7	hSpCas9	negative selection	1782489
66469720	66469743	16	-	26627737	HCT116	viability after 8 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.4718379425034829	[458]	[313,332,403]	5	hSpCas9	negative selection	1864803
66469737	66469760	16	+	26627737	HCT116	viability after 8 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.6388383760698209	[246]	[251,214,169]	6	hSpCas9	negative selection	1864804
66469720	66469743	16	-	26627737	HCT116	viability after 9 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.5533896794045454	[648]	[422,120]	4	hSpCas9	negative selection	1947118
66469737	66469760	16	+	26627737	HCT116	viability after 9 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	-0.7356636790712846	[1131]	[104,241]	-5	hSpCas9	negative selection	1947119
66469720	66469743	16	-	26627737	HCT116	viability after 12 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.8667497602511298	[458]	[434,396,486]	7	hSpCas9	negative selection	2029433
66469737	66469760	16	+	26627737	HCT116	viability after 12 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.2500567297960482	[246]	[140,59,260]	2	hSpCas9	negative selection	2029434
66469720	66469743	16	-	26627737	HCT116	viability after 15 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.5978751498020278	[458]	[292,410,478]	5	hSpCas9	negative selection	2111748
66469737	66469760	16	+	26627737	HCT116	viability after 15 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.5198218339087444	[246]	[234,175,202]	5	hSpCas9	negative selection	2111749
66469720	66469743	16	-	26627737	HCT116	viability after 18 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.7441930657190077	[458]	[152,350,623]	6	hSpCas9	negative selection	2194063
66469737	66469760	16	+	26627737	HCT116	viability after 18 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.4696954063449905	[246]	[124,79,302]	4	hSpCas9	negative selection	2194064
66464628	66464651	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAACTTAGGCTGGGCACAGTGG	BEAN1	ENSG00000166546	-0.3576925563941923	[194,121]	[10,43]	-2	dCas9-VP64	positive selection	2409790
66438289	66438312	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATTGCTTGAATCCGGG	BEAN1	ENSG00000166546	2.433140723417131	[10,9]	[10,13]	7	dCas9-VP64	positive selection	2414353
66450522	66450545	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTTGCTATGTTGCCCAAG	BEAN1	ENSG00000166546	0.7258925451918798	[40,76]	[27,13]	3	dCas9-VP64	positive selection	2423504
66464628	66464651	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAACTTAGGCTGGGCACAGTGG	BEAN1	ENSG00000166546	0.20706651293846912	[72,51]	[21,23]	1	dCas9-VP64	positive selection	2505045
66438289	66438312	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATTGCTTGAATCCGGG	BEAN1	ENSG00000166546	-0.8838793156856553	[97,17]	[18,1]	-8	dCas9-VP64	positive selection	2509608
66450522	66450545	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTTGCTATGTTGCCCAAG	BEAN1	ENSG00000166546	-0.28323094604648114	[112,110]	[38,20]	-3	dCas9-VP64	positive selection	2518759
66469691	66469713	16	+	27760321	OCIAML3	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	-0.27914470862590557	[547,540]	[314,399]	-3	hSpCas9	negative selection	4381638
66469691	66469713	16	+	27760321	OCIAML2	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.5124838164010578	[547,540]	[576,699]	7	hSpCas9	negative selection	4465101
66469691	66469713	16	+	27760321	MV411	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.400565359460487	[547,540]	[491,450]	3	hSpCas9	negative selection	4548564
66469691	66469713	16	+	27760321	HL60	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.4840642623621638	[547,540]	[551,699]	6	hSpCas9	negative selection	4632027
66469691	66469713	16	+	27760321	HT1080	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.4464776750443029	[540,421]	[300,217]	2	hSpCas9	negative selection	4715490
66469691	66469713	16	+	27760321	HT29	viability after 7 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	-0.4170792802362029	[540,421]	[512,475,409]	-6	hSpCas9	negative selection	4798953
66469691	66469713	16	+	27760321	HT29	viability after 25 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	-0.15147759474664746	[540,421]	[413,413,681]	-1	hSpCas9	negative selection	4882416
66469691	66469713	16	+	27760321	HT29	viability after 22 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.05389075392961268	[540,421]	[377,760,599]	0	hSpCas9	negative selection	4965879
66469691	66469713	16	+	27760321	HT29	viability after 19 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.14120395965211074	[540,421]	[646,340,828]	1	hSpCas9	negative selection	5049342
66469691	66469713	16	+	27760321	HT29	viability after 16 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	-0.21180423381929317	[540,421]	[338,518,523]	-2	hSpCas9	negative selection	5132805
66469691	66469713	16	+	27760321	HT29	viability after 13 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.09442934627756416	[540,421]	[641,501,641]	1	hSpCas9	negative selection	5216268
66469691	66469713	16	+	27760321	HT29	viability after 10 days	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.049391860474403415	[540,421]	[439,779,649]	0	hSpCas9	negative selection	5299731
66469691	66469713	16	+	27760321	MOLM13	viability	GCGAGTGCCGTCATAGGTGTGG	BEAN1	ENSG00000166546	0.8185524601968689	[547,540]	[646,454]	6	hSpCas9	negative selection	5383194
66427310	66427333	16	+	27661255	K562	viability	GAGCGCAGTGGCCTCCGAGCGGG	BEAN1	ENSG00000166546	0.25231607337938233	[109,236]	[170,155]	8	dCas9-KRAB	negative selection	5465027
66427674	66427697	16	-	27661255	K562	viability	GGCGCGATCAGGGTCAGCCTCGG	BEAN1	ENSG00000166546	-0.1007487046465948	[454,507]	[398,322]	-4	dCas9-KRAB	negative selection	5465028
66427684	66427707	16	-	27661255	K562	viability	GAGGCCCGAGGGCGCGATCAGGG	BEAN1	ENSG00000166546	0.32265580513742437	[560,646]	[630,576]	9	dCas9-KRAB	negative selection	5465029
66427735	66427758	16	-	27661255	K562	viability	GCTCGTCGGGGACTCGAGTCAGG	BEAN1	ENSG00000166546	0.06217610247940719	[457,553]	[500,351]	2	dCas9-KRAB	negative selection	5465030
66469720	66469743	16	-	27869803	HPAFII	viability after 27 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.20026927883089102	[342]	[186,223,NaN]	1	hSpCas9	negative selection	9557726
66469737	66469760	16	+	27869803	HPAFII	viability after 27 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.3352291675009935	[217]	[316,265,NaN]	9	hSpCas9	negative selection	9557727
66469720	66469743	16	-	27869803	HPAFII	viability after 15 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.62523303198987	[342]	[924,346,NaN]	7	hSpCas9	negative selection	9640175
66469737	66469760	16	+	27869803	HPAFII	viability after 15 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.9326166294729556	[217]	[617,340,NaN]	8	hSpCas9	negative selection	9640176
66469720	66469743	16	-	27869803	ASPC1	viability after 36 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.7380356634143586	[967]	[265,805,573]	7	hSpCas9	negative selection	9722624
66469737	66469760	16	+	27869803	ASPC1	viability after 36 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.533455292640467	[424]	[171,700,389]	9	hSpCas9	negative selection	9722625
66469720	66469743	16	-	27869803	PATU8988S	viability after 35 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	-0.04926761956397835	[753]	[283,302,NaN]	0	hSpCas9	negative selection	9805073
66469737	66469760	16	+	27869803	PATU8988S	viability after 35 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.20192092688039864	[327]	[128,174,NaN]	2	hSpCas9	negative selection	9805074
66469720	66469743	16	-	27869803	PATU8988S	viability after 31 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	-0.3702687387089212	[753]	[214,254,NaN]	-4	hSpCas9	negative selection	9887522
66469737	66469760	16	+	27869803	PATU8988S	viability after 31 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.48736539777734555	[327]	[130,249,NaN]	6	hSpCas9	negative selection	9887523
66469720	66469743	16	-	27869803	HPAFII	viability after 35 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.6076111427034445	[342]	[257,271,NaN]	4	hSpCas9	negative selection	9969971
66469737	66469760	16	+	27869803	HPAFII	viability after 35 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	1.4285497093529147	[217]	[194,411,NaN]	8	hSpCas9	negative selection	9969972
66469720	66469743	16	-	27869803	HPAFII	viability after 31 days	CAATGATGGTGATGCAGGAGAGG	BEAN1	ENSG00000166546	0.5070425194875692	[342]	[341,198,NaN]	3	hSpCas9	negative selection	10052420
66469737	66469760	16	+	27869803	HPAFII	viability after 31 days	TCATTGTGGGCAGCATCCGCAGG	BEAN1	ENSG00000166546	0.9087490579809475	[217]	[166,297,NaN]	6	hSpCas9	negative selection	10052421