Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 675
• Symbol: BRCA2
• Description: BRCA2 DNA repair associated

DataSource: http://genomecrispr.dkfz.de/#!/results/BRCA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
32326587	32326610	13	-	26472758	Jiyoye	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.4715183222719932	[56]	[30]	-3	hSpCas9	negative selection	15944
32337317	32337340	13	+	26472758	Jiyoye	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	3.4071753815058727	[0]	[7]	9	hSpCas9	negative selection	15945
32371015	32371038	13	+	26472758	Jiyoye	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-0.9069332089221896	[91]	[36]	-6	hSpCas9	negative selection	15946
32319127	32319150	13	-	26472758	Jiyoye	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.8567363092688415	[328]	[136]	-6	hSpCas9	negative selection	15947
32332849	32332872	13	+	26472758	Jiyoye	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.2739088506424092	[33]	[30]	2	hSpCas9	negative selection	15948
32339047	32339070	13	+	26472758	Jiyoye	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-3.177787119215283	[47]	[3]	-9	hSpCas9	negative selection	15949
32379397	32379420	13	+	26472758	Jiyoye	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.2919581391345938	[275]	[169]	-2	hSpCas9	negative selection	15950
32380088	32380111	13	-	26472758	Jiyoye	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.512144941107416	[52]	[56]	4	hSpCas9	negative selection	15951
32326525	32326548	13	+	26472758	Jiyoye	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.282224529408277	[178]	[110]	-2	hSpCas9	negative selection	15952
32332939	32332962	13	+	26472758	Jiyoye	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	2.3076397079549595	[14]	[55]	9	hSpCas9	negative selection	15953
32326587	32326610	13	-	26472758	KBM7	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-2.047106009757171	[293,318]	[59,12]	-8	hSpCas9	negative selection	207062
32337317	32337340	13	+	26472758	KBM7	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.6501999243131058	[228,243]	[34,103]	-5	hSpCas9	negative selection	207063
32371015	32371038	13	+	26472758	KBM7	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-3.2201110476193047	[653,358]	[16,31]	-9	hSpCas9	negative selection	207064
32319127	32319150	13	-	26472758	KBM7	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-1.0831391718443562	[756,603]	[92,200]	-7	hSpCas9	negative selection	207065
32332849	32332872	13	+	26472758	KBM7	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-1.1265174415974717	[187,192]	[35,45]	-7	hSpCas9	negative selection	207066
32339047	32339070	13	+	26472758	KBM7	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-2.309986783811051	[220,111]	[8,20]	-9	hSpCas9	negative selection	207067
32379397	32379420	13	+	26472758	KBM7	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-1.4141821214303012	[1336,903]	[227,164]	-7	hSpCas9	negative selection	207068
32380088	32380111	13	-	26472758	KBM7	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.6994230364498022	[301,328]	[163,27]	-5	hSpCas9	negative selection	207069
32326525	32326548	13	+	26472758	KBM7	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-2.4321459957459446	[1062,1129]	[137,58]	-9	hSpCas9	negative selection	207070
32332939	32332962	13	+	26472758	KBM7	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-1.2868427111900986	[345,288]	[52,67]	-7	hSpCas9	negative selection	207071
32326587	32326610	13	-	26472758	Raji	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	0.08184844326646179	[113]	[27]	0	hSpCas9	negative selection	398180
32337317	32337340	13	+	26472758	Raji	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-2.6768877735709635	[247]	[8]	-9	hSpCas9	negative selection	398181
32371015	32371038	13	+	26472758	Raji	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-0.5930561827674925	[155]	[23]	-5	hSpCas9	negative selection	398182
32319127	32319150	13	-	26472758	Raji	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.9181515567335382	[455]	[55]	-6	hSpCas9	negative selection	398183
32332849	32332872	13	+	26472758	Raji	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	1.1744977312321367	[62]	[32]	8	hSpCas9	negative selection	398184
32339047	32339070	13	+	26472758	Raji	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.23291441745745844	[54]	[14]	2	hSpCas9	negative selection	398185
32379397	32379420	13	+	26472758	Raji	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-1.0284998927081737	[711]	[80]	-6	hSpCas9	negative selection	398186
32380088	32380111	13	-	26472758	Raji	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.24745918198649808	[132]	[25]	-2	hSpCas9	negative selection	398187
32326525	32326548	13	+	26472758	Raji	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-1.0758382886821707	[762]	[83]	-7	hSpCas9	negative selection	398188
32332939	32332962	13	+	26472758	Raji	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.0684645460812971	[262]	[63]	0	hSpCas9	negative selection	398189
32326587	32326610	13	-	26472758	K562	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.12185294461713336	[222]	[172]	-1	hSpCas9	negative selection	589298
32337317	32337340	13	+	26472758	K562	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-1.5475882300577213	[186]	[53]	-6	hSpCas9	negative selection	589299
32371015	32371038	13	+	26472758	K562	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.57823533077404	[473]	[66]	-8	hSpCas9	negative selection	589300
32319127	32319150	13	-	26472758	K562	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.26468175853940057	[638]	[448]	-2	hSpCas9	negative selection	589301
32332849	32332872	13	+	26472758	K562	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.09061339158741166	[177]	[159]	0	hSpCas9	negative selection	589302
32339047	32339070	13	+	26472758	K562	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.6507390098441819	[82]	[109]	5	hSpCas9	negative selection	589303
32379397	32379420	13	+	26472758	K562	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	0.011441555688832983	[911]	[775]	0	hSpCas9	negative selection	589304
32380088	32380111	13	-	26472758	K562	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.17932369944456206	[203]	[194]	1	hSpCas9	negative selection	589305
32326525	32326548	13	+	26472758	K562	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	0.4093815757649917	[808]	[906]	3	hSpCas9	negative selection	589306
32332939	32332962	13	+	26472758	K562	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.44643735881861246	[325]	[374]	3	hSpCas9	negative selection	589307
32316506	32316529	13	+	26627737	DLD1	viability	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-2.5021734281802845	[300]	[17,33,0]	-9	hSpCas9	negative selection	786659
32326587	32326610	13	-	26627737	DLD1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.3612989545544867	[171]	[38,13,10]	-8	hSpCas9	negative selection	786660
32333077	32333100	13	+	26627737	DLD1	viability	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.5246389950598536	[150]	[76,79,49]	5	hSpCas9	negative selection	786661
32339876	32339899	13	-	26627737	DLD1	viability	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-1.1945509198737931	[392]	[30,105,29]	-8	hSpCas9	negative selection	786662
32356493	32356516	13	+	26627737	DLD1	viability	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.5880688900773834	[258]	[80,75,11]	-5	hSpCas9	negative selection	786663
32357889	32357912	13	+	26627737	DLD1	viability	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.5172186070686107	[307]	[61,205,146]	5	hSpCas9	negative selection	786664
32316506	32316529	13	+	26627737	GBM cells	viability after 5 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.7211213927490967	[228]	[71,76]	-8	hSpCas9	negative selection	868974
32326587	32326610	13	-	26627737	GBM cells	viability after 5 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.40556524924545956	[225]	[71,110]	-6	hSpCas9	negative selection	868975
32333077	32333100	13	+	26627737	GBM cells	viability after 5 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.05454353917728427	[182]	[86,101]	-1	hSpCas9	negative selection	868976
32339876	32339899	13	-	26627737	GBM cells	viability after 5 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	0.23594886216325617	[303]	[224,158]	3	hSpCas9	negative selection	868977
32356493	32356516	13	+	26627737	GBM cells	viability after 5 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.6559913919792907	[284]	[99,93]	-8	hSpCas9	negative selection	868978
32357889	32357912	13	+	26627737	GBM cells	viability after 5 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.3244108211461369	[257]	[99,120]	-5	hSpCas9	negative selection	868979
32316506	32316529	13	+	26627737	GBM cells	viability after 13 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-1.3631054555585616	[228]	[28,63]	-8	hSpCas9	negative selection	951289
32326587	32326610	13	-	26627737	GBM cells	viability after 13 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.7988254554681168	[225]	[75,65]	-7	hSpCas9	negative selection	951290
32333077	32333100	13	+	26627737	GBM cells	viability after 13 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.06955933530319591	[182]	[87,99]	-1	hSpCas9	negative selection	951291
32339876	32339899	13	-	26627737	GBM cells	viability after 13 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	0.5362403198098352	[303]	[295,192]	6	hSpCas9	negative selection	951292
32356493	32356516	13	+	26627737	GBM cells	viability after 13 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.2506736109669905	[284]	[140,120]	-3	hSpCas9	negative selection	951293
32357889	32357912	13	+	26627737	GBM cells	viability after 13 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.17277548254873815	[257]	[159,155]	2	hSpCas9	negative selection	951294
32316506	32316529	13	+	26627737	GBM cells	viability after 21 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-1.5431817811454331	[228]	[49,35]	-8	hSpCas9	negative selection	1033604
32326587	32326610	13	-	26627737	GBM cells	viability after 21 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-2.5808306081467656	[225]	[19,20]	-9	hSpCas9	negative selection	1033605
32333077	32333100	13	+	26627737	GBM cells	viability after 21 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.3678475137952253	[182]	[75,77]	-3	hSpCas9	negative selection	1033606
32339876	32339899	13	-	26627737	GBM cells	viability after 21 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.04466448093973954	[303]	[168,151]	0	hSpCas9	negative selection	1033607
32356493	32356516	13	+	26627737	GBM cells	viability after 21 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.7703175427330745	[284]	[95,85]	-6	hSpCas9	negative selection	1033608
32357889	32357912	13	+	26627737	GBM cells	viability after 21 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.31863835269162516	[257]	[114,109]	-3	hSpCas9	negative selection	1033609
32316506	32316529	13	+	26627737	RPE1	viability after 9 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-3.3281210381873856	[632]	[10,30]	-9	hSpCas9	negative selection	1115919
32326587	32326610	13	-	26627737	RPE1	viability after 9 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.2903162294565047	[294]	[42,30]	-7	hSpCas9	negative selection	1115920
32333077	32333100	13	+	26627737	RPE1	viability after 9 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.05172088129562043	[783]	[293,162]	0	hSpCas9	negative selection	1115921
32339876	32339899	13	-	26627737	RPE1	viability after 9 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-1.494564848414464	[940]	[128,72]	-8	hSpCas9	negative selection	1115922
32356493	32356516	13	+	26627737	RPE1	viability after 9 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-1.0131179750560915	[1047]	[131,201]	-6	hSpCas9	negative selection	1115923
32357889	32357912	13	+	26627737	RPE1	viability after 9 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-2.1468424755806383	[1353]	[110,75]	-9	hSpCas9	negative selection	1115924
32316506	32316529	13	+	26627737	RPE1	viability after 12 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-4.53923329470017	[632]	[0,13]	-9	hSpCas9	negative selection	1198234
32326587	32326610	13	-	26627737	RPE1	viability after 12 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	0.14909703844079436	[294]	[100,73]	1	hSpCas9	negative selection	1198235
32333077	32333100	13	+	26627737	RPE1	viability after 12 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.44860352487806976	[783]	[182,123]	-3	hSpCas9	negative selection	1198236
32339876	32339899	13	-	26627737	RPE1	viability after 12 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-1.7199789285729228	[940]	[101,49]	-8	hSpCas9	negative selection	1198237
32356493	32356516	13	+	26627737	RPE1	viability after 12 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-1.8210623877809669	[1047]	[51,108]	-8	hSpCas9	negative selection	1198238
32357889	32357912	13	+	26627737	RPE1	viability after 12 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-2.0863989608989657	[1353]	[107,61]	-8	hSpCas9	negative selection	1198239
32316506	32316529	13	+	26627737	RPE1	viability after 15 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-7.484312815556447	[632]	[0,0]	-9	hSpCas9	negative selection	1280549
32326587	32326610	13	-	26627737	RPE1	viability after 15 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	0.3341872399679593	[294]	[121,88]	2	hSpCas9	negative selection	1280550
32333077	32333100	13	+	26627737	RPE1	viability after 15 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.3894379800178014	[783]	[179,158]	-2	hSpCas9	negative selection	1280551
32339876	32339899	13	-	26627737	RPE1	viability after 15 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-1.2453669737339212	[940]	[180,45]	-6	hSpCas9	negative selection	1280552
32356493	32356516	13	+	26627737	RPE1	viability after 15 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-2.5072227418971167	[1047]	[43,59]	-8	hSpCas9	negative selection	1280553
32357889	32357912	13	+	26627737	RPE1	viability after 15 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-3.3493144018429817	[1353]	[32,41]	-9	hSpCas9	negative selection	1280554
32316506	32316529	13	+	26627737	RPE1	viability after 18 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-7.416393429327599	[632]	[0,0]	-9	hSpCas9	negative selection	1362864
32326587	32326610	13	-	26627737	RPE1	viability after 18 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.6681778334445987	[294]	[52,46]	-4	hSpCas9	negative selection	1362865
32333077	32333100	13	+	26627737	RPE1	viability after 18 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.9980890130939533	[783]	[132,76]	-6	hSpCas9	negative selection	1362866
32339876	32339899	13	-	26627737	RPE1	viability after 18 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-1.5363512839511064	[940]	[88,85]	-7	hSpCas9	negative selection	1362867
32356493	32356516	13	+	26627737	RPE1	viability after 18 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-1.7450211790411205	[1047]	[36,134]	-8	hSpCas9	negative selection	1362868
32357889	32357912	13	+	26627737	RPE1	viability after 18 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-3.7541576312450675	[1353]	[43,8]	-9	hSpCas9	negative selection	1362869
32316506	32316529	13	+	26627737	HeLa	viability after 8 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.25460375396738455	[303]	[172,42,128]	-2	hSpCas9	negative selection	1445179
32326587	32326610	13	-	26627737	HeLa	viability after 8 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.16408603878099387	[321]	[180,118,89]	-1	hSpCas9	negative selection	1445180
32333077	32333100	13	+	26627737	HeLa	viability after 8 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	1.0283055153881628	[111]	[149,128,34]	7	hSpCas9	negative selection	1445181
32339876	32339899	13	-	26627737	HeLa	viability after 8 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.20478303553334687	[690]	[433,158,229]	-2	hSpCas9	negative selection	1445182
32356493	32356516	13	+	26627737	HeLa	viability after 8 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.012780653938428276	[404]	[263,119,168]	0	hSpCas9	negative selection	1445183
32357889	32357912	13	+	26627737	HeLa	viability after 8 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.6035377232586145	[435]	[213,383,252]	5	hSpCas9	negative selection	1445184
32316506	32316529	13	+	26627737	HeLa	viability after 12 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.571354931793801	[303]	[29,103,115]	-5	hSpCas9	negative selection	1527494
32326587	32326610	13	-	26627737	HeLa	viability after 12 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.1485746240401122	[321]	[104,6,74]	-8	hSpCas9	negative selection	1527495
32333077	32333100	13	+	26627737	HeLa	viability after 12 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.784775969634695	[111]	[27,95,111]	6	hSpCas9	negative selection	1527496
32339876	32339899	13	-	26627737	HeLa	viability after 12 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.11668102791450474	[690]	[340,134,329]	-1	hSpCas9	negative selection	1527497
32356493	32356516	13	+	26627737	HeLa	viability after 12 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.1467558518411654	[404]	[146,201,203]	1	hSpCas9	negative selection	1527498
32357889	32357912	13	+	26627737	HeLa	viability after 12 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-1.102402347324655	[435]	[18,110,116]	-7	hSpCas9	negative selection	1527499
32316506	32316529	13	+	26627737	HeLa	viability after 15 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.268045016662734	[303]	[277,107,51]	2	hSpCas9	negative selection	1609809
32326587	32326610	13	-	26627737	HeLa	viability after 15 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.4042354004023956	[321]	[23,25,102]	-8	hSpCas9	negative selection	1609810
32333077	32333100	13	+	26627737	HeLa	viability after 15 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	1.0933434283346568	[111]	[13,47,241]	7	hSpCas9	negative selection	1609811
32339876	32339899	13	-	26627737	HeLa	viability after 15 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.09562053084699429	[690]	[390,171,221]	-1	hSpCas9	negative selection	1609812
32356493	32356516	13	+	26627737	HeLa	viability after 15 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.9211232328110306	[404]	[11,116,136]	-7	hSpCas9	negative selection	1609813
32357889	32357912	13	+	26627737	HeLa	viability after 15 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-1.5551807420488055	[435]	[5,65,113]	-8	hSpCas9	negative selection	1609814
32316506	32316529	13	+	26627737	HeLa	viability after 18 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.1952157488592652	[303]	[170,90,51]	1	hSpCas9	negative selection	1692124
32326587	32326610	13	-	26627737	HeLa	viability after 18 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.4181720145535557	[321]	[13,22,102]	-8	hSpCas9	negative selection	1692125
32333077	32333100	13	+	26627737	HeLa	viability after 18 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	1.1100963647317466	[111]	[12,37,241]	7	hSpCas9	negative selection	1692126
32339876	32339899	13	-	26627737	HeLa	viability after 18 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.07682491514376444	[690]	[266,144,221]	0	hSpCas9	negative selection	1692127
32356493	32356516	13	+	26627737	HeLa	viability after 18 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.9395959510983944	[404]	[8,92,136]	-7	hSpCas9	negative selection	1692128
32357889	32357912	13	+	26627737	HeLa	viability after 18 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-1.5325866301810929	[435]	[3,56,113]	-8	hSpCas9	negative selection	1692129
32316506	32316529	13	+	26627737	HCT116	viability after 6 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.158110515403616	[667]	[77,102]	-1	hSpCas9	negative selection	1774439
32326587	32326610	13	-	26627737	HCT116	viability after 6 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-3.613928385433425	[570]	[16,1]	-9	hSpCas9	negative selection	1774440
32333077	32333100	13	+	26627737	HCT116	viability after 6 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-1.9298484071410078	[424]	[3,24]	-8	hSpCas9	negative selection	1774441
32339876	32339899	13	-	26627737	HCT116	viability after 6 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	1.0913912032572743	[424]	[220,98]	6	hSpCas9	negative selection	1774442
32356493	32356516	13	+	26627737	HCT116	viability after 6 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	2.990104019674111	[298]	[1037,6]	9	hSpCas9	negative selection	1774443
32357889	32357912	13	+	26627737	HCT116	viability after 6 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.5646336869613884	[650]	[229,107]	3	hSpCas9	negative selection	1774444
32316506	32316529	13	+	26627737	HCT116	viability after 8 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.2581378347882039	[207]	[105,195,108]	3	hSpCas9	negative selection	1856754
32326587	32326610	13	-	26627737	HCT116	viability after 8 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.103674390782155	[255]	[16,108,69]	-8	hSpCas9	negative selection	1856755
32333077	32333100	13	+	26627737	HCT116	viability after 8 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.22618434250074748	[177]	[48,123,77]	-3	hSpCas9	negative selection	1856756
32339876	32339899	13	-	26627737	HCT116	viability after 8 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.4228568462258272	[519]	[173,210,254]	-5	hSpCas9	negative selection	1856757
32356493	32356516	13	+	26627737	HCT116	viability after 8 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.6989818820702723	[185]	[201,149,147]	6	hSpCas9	negative selection	1856758
32357889	32357912	13	+	26627737	HCT116	viability after 8 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.39468807349667107	[294]	[161,116,92]	-5	hSpCas9	negative selection	1856759
32316506	32316529	13	+	26627737	HCT116	viability after 9 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.2946880057646807	[667]	[274,42]	-2	hSpCas9	negative selection	1939069
32326587	32326610	13	-	26627737	HCT116	viability after 9 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-3.4329835258869	[570]	[12,14]	-9	hSpCas9	negative selection	1939070
32333077	32333100	13	+	26627737	HCT116	viability after 9 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-1.104060136712091	[424]	[111,5]	-7	hSpCas9	negative selection	1939071
32339876	32339899	13	-	26627737	HCT116	viability after 9 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	0.8504855675724149	[424]	[88,295]	6	hSpCas9	negative selection	1939072
32356493	32356516	13	+	26627737	HCT116	viability after 9 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	1.007053169295082	[298]	[322,31]	7	hSpCas9	negative selection	1939073
32357889	32357912	13	+	26627737	HCT116	viability after 9 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.6922547030870657	[650]	[324,245]	5	hSpCas9	negative selection	1939074
32316506	32316529	13	+	26627737	HCT116	viability after 12 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.590478662538859	[207]	[40,131,48]	-6	hSpCas9	negative selection	2021384
32326587	32326610	13	-	26627737	HCT116	viability after 12 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.8474555323982225	[255]	[35,25,49]	-9	hSpCas9	negative selection	2021385
32333077	32333100	13	+	26627737	HCT116	viability after 12 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.32984713040453634	[177]	[79,157,118]	3	hSpCas9	negative selection	2021386
32339876	32339899	13	-	26627737	HCT116	viability after 12 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.9586056259716513	[519]	[79,174,172]	-8	hSpCas9	negative selection	2021387
32356493	32356516	13	+	26627737	HCT116	viability after 12 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.7033162784332304	[185]	[78,137,266]	6	hSpCas9	negative selection	2021388
32357889	32357912	13	+	26627737	HCT116	viability after 12 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.24253193074126633	[294]	[99,95,198]	-3	hSpCas9	negative selection	2021389
32316506	32316529	13	+	26627737	HCT116	viability after 15 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-1.0407125332990317	[207]	[26,50,91]	-8	hSpCas9	negative selection	2103699
32326587	32326610	13	-	26627737	HCT116	viability after 15 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.7198874337812624	[255]	[70,12,52]	-9	hSpCas9	negative selection	2103700
32333077	32333100	13	+	26627737	HCT116	viability after 15 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.2127572788630694	[177]	[161,104,93]	2	hSpCas9	negative selection	2103701
32339876	32339899	13	-	26627737	HCT116	viability after 15 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.8557403366690055	[519]	[238,177,87]	-7	hSpCas9	negative selection	2103702
32356493	32356516	13	+	26627737	HCT116	viability after 15 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.09643707211283625	[185]	[26,190,113]	1	hSpCas9	negative selection	2103703
32357889	32357912	13	+	26627737	HCT116	viability after 15 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.2877314994360209	[294]	[229,103,93]	-3	hSpCas9	negative selection	2103704
32316506	32316529	13	+	26627737	HCT116	viability after 18 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.4031815453771601	[207]	[101,74,49]	-4	hSpCas9	negative selection	2186014
32326587	32326610	13	-	26627737	HCT116	viability after 18 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.46244216365357	[255]	[59,44,28]	-8	hSpCas9	negative selection	2186015
32333077	32333100	13	+	26627737	HCT116	viability after 18 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	-0.8197421668387515	[177]	[29,32,85]	-6	hSpCas9	negative selection	2186016
32339876	32339899	13	-	26627737	HCT116	viability after 18 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.8326850945119367	[519]	[110,225,77]	-6	hSpCas9	negative selection	2186017
32356493	32356516	13	+	26627737	HCT116	viability after 18 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.03011946291245604	[185]	[108,62,105]	0	hSpCas9	negative selection	2186018
32357889	32357912	13	+	26627737	HCT116	viability after 18 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.34967127687098604	[294]	[76,89,172]	-3	hSpCas9	negative selection	2186019
32316462	32316485	13	+	24336569	HL60	viability	TGCCTATTGGATCCAAAGAGAGG	BRCA2	ENSG00000139618	-1.4784368841457487	[290]	[220]	-8	hSpCas9	negative selection	2250289
32316506	32316529	13	+	24336569	HL60	viability	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.11430843364530241	[1007]	[2308]	1	hSpCas9	negative selection	2250290
32319080	32319103	13	+	24336569	HL60	viability	TAGGACCAATAAGTCTTAATTGG	BRCA2	ENSG00000139618	1.0222472488932115	[160]	[691]	7	hSpCas9	negative selection	2250291
32319085	32319108	13	-	24336569	HL60	viability	TCAAACCAATTAAGACTTATTGG	BRCA2	ENSG00000139618	-0.057047573895839206	[497]	[1012]	0	hSpCas9	negative selection	2250292
32319127	32319150	13	-	24336569	HL60	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-1.803218444558931	[911]	[552]	-9	hSpCas9	negative selection	2250293
32319145	32319168	13	-	24336569	HL60	viability	TTATGTTCAGATTCTTCTGCAGG	BRCA2	ENSG00000139618	0.49378324525904804	[297]	[887]	4	hSpCas9	negative selection	2250294
32319202	32319225	13	-	24336569	HL60	viability	TTATAAGATGGTTTCCTTTGTGG	BRCA2	ENSG00000139618	0.8755449654737847	[280]	[1090]	7	hSpCas9	negative selection	2250295
32319210	32319233	13	+	24336569	HL60	viability	GAAACCATCTTATAATCAGCTGG	BRCA2	ENSG00000139618	0.3968303387957766	[448]	[1250]	3	hSpCas9	negative selection	2250296
32319241	32319264	13	-	24336569	HL60	viability	CCTTGCTCTTTGAATATTATTGG	BRCA2	ENSG00000139618	-0.6355891974274593	[242]	[330]	-5	hSpCas9	negative selection	2250297
32319274	32319297	13	-	24336569	HL60	viability	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	0.23686774385232756	[240]	[600]	2	hSpCas9	negative selection	2250298
32316462	32316485	13	+	24336569	KBM7	viability	TGCCTATTGGATCCAAAGAGAGG	BRCA2	ENSG00000139618	-1.0421918673037578	[224]	[297]	-6	hSpCas9	negative selection	2317466
32316506	32316529	13	+	24336569	KBM7	viability	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-1.7985469643875986	[689]	[540]	-8	hSpCas9	negative selection	2317467
32319080	32319103	13	+	24336569	KBM7	viability	TAGGACCAATAAGTCTTAATTGG	BRCA2	ENSG00000139618	0.5375475269695875	[194]	[771]	5	hSpCas9	negative selection	2317468
32319085	32319108	13	-	24336569	KBM7	viability	TCAAACCAATTAAGACTTATTGG	BRCA2	ENSG00000139618	-0.0013862969216534363	[417]	[1138]	0	hSpCas9	negative selection	2317469
32319127	32319150	13	-	24336569	KBM7	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-3.3629313709055975	[512]	[135]	-9	hSpCas9	negative selection	2317470
32319145	32319168	13	-	24336569	KBM7	viability	TTATGTTCAGATTCTTCTGCAGG	BRCA2	ENSG00000139618	0.28762593975288636	[327]	[1091]	2	hSpCas9	negative selection	2317471
32319202	32319225	13	-	24336569	KBM7	viability	TTATAAGATGGTTTCCTTTGTGG	BRCA2	ENSG00000139618	0.15043945699772004	[439]	[1331]	1	hSpCas9	negative selection	2317472
32319210	32319233	13	+	24336569	KBM7	viability	GAAACCATCTTATAATCAGCTGG	BRCA2	ENSG00000139618	-0.6320849296812618	[403]	[710]	-5	hSpCas9	negative selection	2317473
32319241	32319264	13	-	24336569	KBM7	viability	CCTTGCTCTTTGAATATTATTGG	BRCA2	ENSG00000139618	1.8137488873345082	[140]	[1351]	9	hSpCas9	negative selection	2317474
32319274	32319297	13	-	24336569	KBM7	viability	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-2.642082220711861	[221]	[96]	-9	hSpCas9	negative selection	2317475
32367325	32367348	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTGGGAGGCTGAGGCAGGGAG	BRCA2	ENSG00000139618	1.0311422578945828	[46,428]	[158,53]	4	dCas9-VP64	positive selection	2400116
32367325	32367348	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTGGGAGGCTGAGGCAGGGAG	BRCA2	ENSG00000139618	0.6350691816100226	[174,241]	[44,161]	5	dCas9-VP64	positive selection	2495371
32326586	32326609	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	-0.035304180323415896	[3,3]	[2,2]	0	hSpCas9	positive selection	2973652
32319127	32319150	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.5787381402223126	[3,3]	[3,0]	-7	hSpCas9	positive selection	2973653
32337132	32337155	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	0.2429178453976281	[3,3]	[5,2]	5	hSpCas9	positive selection	2973654
32319274	32319297	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-1.0964407651588033	[3,3]	[1,0]	-9	hSpCas9	positive selection	2973655
32326586	32326609	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	-0.04811976874499302	[3,3]	[4,0]	0	hSpCas9	positive selection	3041510
32319127	32319150	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.3830381766327525	[3,3]	[3,0]	-5	hSpCas9	positive selection	3041511
32337132	32337155	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	-0.12826751766451763	[3,3]	[3,0]	-2	hSpCas9	positive selection	3041512
32319274	32319297	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-0.7907482019372338	[3,3]	[2,0]	-9	hSpCas9	positive selection	3041513
32344579	32344602		+	24336571	A375	resistance to PLX after 7 days	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.17436440955155041	[4,5]	[5,5]	5	hSpCas9	positive selection	3150720
32340091	32340114		+	24336571	A375	resistance to PLX after 7 days	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.24089994278164403	[14,14]	[12,12]	-7	hSpCas9	positive selection	3150731
32337866	32337889		-	24336571	A375	resistance to PLX after 7 days	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.09370715917890282	[5,7]	[6,6]	3	hSpCas9	positive selection	3150742
32344579	32344602		+	24336571	A375	resistance to PLX after 14 days	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.39282346599313045	[3,3]	[1,1]	4	hSpCas9	positive selection	3208513
32340091	32340114		+	24336571	A375	resistance to PLX after 14 days	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.26249100062236286	[14,12]	[5,4]	-3	hSpCas9	positive selection	3208524
32337866	32337889		-	24336571	A375	resistance to PLX after 14 days	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.15994781904360977	[8,5]	[2,2]	-2	hSpCas9	positive selection	3208535
32344579	32344602		+	24336571	A375	viability after 7 days	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-1.1406076341085343	[12]	[4,5]	-9	hSpCas9	negative selection	3266306
32340091	32340114		+	24336571	A375	viability after 7 days	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.20464956377067808	[13]	[14,14]	3	hSpCas9	negative selection	3266317
32337866	32337889		-	24336571	A375	viability after 7 days	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.438050326865938	[20]	[5,7]	-9	hSpCas9	negative selection	3266328
32344579	32344602		+	24336571	A375	viability after 14 days	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-1.4855180998932498	[12]	[3,3]	-9	hSpCas9	negative selection	3324099
32340091	32340114		+	24336571	A375	viability after 14 days	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.11860995044176692	[13]	[14,12]	1	hSpCas9	negative selection	3324110
32337866	32337889		-	24336571	A375	viability after 14 days	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.3269409574324071	[20]	[8,5]	-9	hSpCas9	negative selection	3324121
32337866	32337889	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	2.348237103321683	[36,22]	[0,0]	8	hSpCas9	positive selection	3339051
32340091	32340114	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.17000204420347378	[133,137]	[0,0]	0	hSpCas9	positive selection	3339052
32346875	32346898	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	-1.8622930744534236	[595,515]	[0,0]	-9	hSpCas9	positive selection	3339053
32346881	32346904	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.5944228299702223	[230,230]	[0,0]	-4	hSpCas9	positive selection	3358295
32344579	32344602	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.7426737885541649	[255,255]	[0,0]	-5	hSpCas9	positive selection	3358296
32344610	32344633	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.8310614567437372	[85,85]	[0,0]	4	hSpCas9	positive selection	3358297
32326586	32326609	13	-	26780180	HT29	viability (Avana library 4 designs)	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	3.10513325323419	[]	[]	8	hSpCas9	negative selection	3409849
32319127	32319150	13	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	3.02589813209064	[]	[]	8	hSpCas9	negative selection	3409850
32337132	32337155	13	-	26780180	HT29	viability (Avana library 4 designs)	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	1.81647984691089	[]	[]	7	hSpCas9	negative selection	3409851
32319274	32319297	13	-	26780180	HT29	viability (Avana library 4 designs)	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	3.12346772770446	[]	[]	8	hSpCas9	negative selection	3409852
32319127	32319150	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-7.61620680598792	[]	[]	-7	hSpCas9	negative selection	3484065
32319274	32319297	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-10.1446824564546	[]	[]	-7	hSpCas9	negative selection	3484066
32337132	32337155	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	-21.3935821140186	[]	[]	-9	hSpCas9	negative selection	3484067
32326586	32326609	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	-7.68092894449741	[]	[]	-7	hSpCas9	negative selection	3484068
32337539	32337562	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATACAGTATTAATTGACTGAGG	BRCA2	ENSG00000139618	-2.86965090165147	[]	[]	-3	hSpCas9	negative selection	3484069
32338460	32338483	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGCCAGTTTATGAAGGAGGG	BRCA2	ENSG00000139618	-0.888824072764217	[]	[]	-1	hSpCas9	negative selection	3484070
32319127	32319150	13	-	26780180	A375	viability (Avana lentiGuide)	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	4.97394011116435	[]	[]	4	hSpCas9	negative selection	3592724
32319274	32319297	13	-	26780180	A375	viability (Avana lentiGuide)	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	12.5222135657082	[]	[]	7	hSpCas9	negative selection	3592725
32337132	32337155	13	-	26780180	A375	viability (Avana lentiGuide)	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	9.43435581218951	[]	[]	6	hSpCas9	negative selection	3592726
32326586	32326609	13	-	26780180	A375	viability (Avana lentiGuide)	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	10.229344986435	[]	[]	7	hSpCas9	negative selection	3592727
32337539	32337562	13	-	26780180	A375	viability (Avana lentiGuide)	GATACAGTATTAATTGACTGAGG	BRCA2	ENSG00000139618	6.98146073246511	[]	[]	5	hSpCas9	negative selection	3592728
32338460	32338483	13	+	26780180	A375	viability (Avana lentiGuide)	TCTGGCCAGTTTATGAAGGAGGG	BRCA2	ENSG00000139618	8.87909354746745	[]	[]	6	hSpCas9	negative selection	3592729
32319127	32319150	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.9445687490742652	[4]	[2,1]	-8	hSpCas9	positive selection	3701383
32319274	32319297	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-0.286753096044891	[6]	[4,4]	-4	hSpCas9	positive selection	3701384
32337132	32337155	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	-1.1708840748392264	[7]	[3,1]	-9	hSpCas9	positive selection	3701385
32326586	32326609	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	-0.05038328688592983	[5]	[4,5]	-1	hSpCas9	positive selection	3701386
32337539	32337562	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATACAGTATTAATTGACTGAGG	BRCA2	ENSG00000139618	-0.43860978663869044	[8]	[6,5]	-6	hSpCas9	positive selection	3701387
32338460	32338483	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGCCAGTTTATGAAGGAGGG	BRCA2	ENSG00000139618	0.10332491596808176	[4]	[5,4]	2	hSpCas9	positive selection	3701388
32319127	32319150	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.2552977721077104	[5]	[2,3]	-3	hSpCas9	positive selection	3809990
32319274	32319297	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTACAGGAGATTGGTACAGCGG	BRCA2	ENSG00000139618	-0.572399159676495	[5]	[4,1]	-6	hSpCas9	positive selection	3809991
32337132	32337155	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGTCTCCATATAAAACCATGG	BRCA2	ENSG00000139618	-0.5032696918216022	[5]	[5,1]	-6	hSpCas9	positive selection	3809992
32326586	32326609	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCACAGTAGAACTAAGGGTGGG	BRCA2	ENSG00000139618	-0.48134953341611725	[5]	[2,2]	-6	hSpCas9	positive selection	3809993
32337539	32337562	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATACAGTATTAATTGACTGAGG	BRCA2	ENSG00000139618	-0.2404447923294749	[5]	[3,3]	-3	hSpCas9	positive selection	3809994
32338460	32338483	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGCCAGTTTATGAAGGAGGG	BRCA2	ENSG00000139618	-0.49429274531372336	[5]	[0,4]	-6	hSpCas9	positive selection	3809995
32344610	32344633	13	+	26780180	A375	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.681317443709095	[]	[]	2	hSpCas9	negative selection	3918246
32344579	32344602	13	+	26780180	A375	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	1.13608999444418	[]	[]	6	hSpCas9	negative selection	3918247
32340091	32340114	13	+	26780180	A375	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	1.28623496883186	[]	[]	7	hSpCas9	negative selection	3918248
32346875	32346898	13	+	26780180	A375	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.730148045559358	[]	[]	2	hSpCas9	negative selection	3918249
32337866	32337889	13	-	26780180	A375	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	1.01998092849363	[]	[]	5	hSpCas9	negative selection	3918250
32346881	32346904	13	-	26780180	A375	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	1.84796322670001	[]	[]	9	hSpCas9	negative selection	3918251
32344610	32344633	13	+	26780180	HT29	viability (GeCKOv2 library)	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.639249903551464	[]	[]	2	hSpCas9	negative selection	4026212
32344579	32344602	13	+	26780180	HT29	viability (GeCKOv2 library)	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	1.10108825611125	[]	[]	5	hSpCas9	negative selection	4026213
32340091	32340114	13	+	26780180	HT29	viability (GeCKOv2 library)	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	1.11882899238743	[]	[]	5	hSpCas9	negative selection	4026214
32346875	32346898	13	+	26780180	HT29	viability (GeCKOv2 library)	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.695040767858807	[]	[]	2	hSpCas9	negative selection	4026215
32337866	32337889	13	-	26780180	HT29	viability (GeCKOv2 library)	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.973347492353144	[]	[]	4	hSpCas9	negative selection	4026216
32346881	32346904	13	-	26780180	HT29	viability (GeCKOv2 library)	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	1.84657887414998	[]	[]	8	hSpCas9	negative selection	4026217
32344579	32344602	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.1083315724987246	[2]	[1,0]	-3	hSpCas9	positive selection	4177144
32340091	32340114	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.07157342901737936	[3]	[2,2]	1	hSpCas9	positive selection	4177155
32337866	32337889	13	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.052691214649443874	[3]	[2,1]	1	hSpCas9	positive selection	4177166
32344579	32344602	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.7601194291030657	[2]	[0,0,0,0]	-9	hSpCas9	positive selection	4241166
32340091	32340114	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.04626722487779233	[3]	[0,3,2,0]	0	hSpCas9	positive selection	4241177
32337866	32337889	13	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.9197362131869334	[4]	[0,0,0,0]	-9	hSpCas9	positive selection	4241188
32337866	32337889	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.4846451798198088	[1]	[1,0]	-8	hSpCas9	positive selection	4258465
32340091	32340114	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.2659695300768048	[2]	[2,2]	5	hSpCas9	positive selection	4258466
32346875	32346898	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.2709645373435535	[4]	[4,3]	5	hSpCas9	positive selection	4258467
32346881	32346904	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.6222836907471888	[3]	[2,0]	-8	hSpCas9	positive selection	4322749
32344579	32344602	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.3064549717081626	[3]	[3,3]	6	hSpCas9	positive selection	4322750
32344610	32344633	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.34855493743796395	[2]	[3,1]	7	hSpCas9	positive selection	4322751
32326495	32326517	13	-	27760321	OCIAML3	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.580227739083812	[468,461]	[115,129]	-8	hSpCas9	negative selection	4382194
32337864	32337886	13	-	27760321	OCIAML3	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.9803374956060306	[545,438]	[194,192]	-7	hSpCas9	negative selection	4382195
32338873	32338895	13	-	27760321	OCIAML3	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.561123075786907	[683,594]	[302,383]	-5	hSpCas9	negative selection	4382196
32338921	32338943	13	+	27760321	OCIAML3	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.40200575781156633	[225,185]	[220,199]	5	hSpCas9	negative selection	4382197
32339025	32339047	13	-	27760321	OCIAML3	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.4760425090738185	[204,178]	[62,165]	-5	hSpCas9	negative selection	4382198
32326495	32326517	13	-	27760321	OCIAML2	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.9110333994878258	[468,461]	[167,243]	-7	hSpCas9	negative selection	4465657
32337864	32337886	13	-	27760321	OCIAML2	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-1.1057305370216288	[545,438]	[212,145]	-8	hSpCas9	negative selection	4465658
32338873	32338895	13	-	27760321	OCIAML2	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.8183172694848961	[683,594]	[236,365]	-7	hSpCas9	negative selection	4465659
32338921	32338943	13	+	27760321	OCIAML2	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.25300518370963687	[225,185]	[163,241]	3	hSpCas9	negative selection	4465660
32339025	32339047	13	-	27760321	OCIAML2	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.045608696618247624	[204,178]	[128,177]	0	hSpCas9	negative selection	4465661
32326495	32326517	13	-	27760321	MV411	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.2585443530370865	[468,461]	[340,131]	-2	hSpCas9	negative selection	4549120
32337864	32337886	13	-	27760321	MV411	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	0.11770935153415146	[545,438]	[161,633]	0	hSpCas9	negative selection	4549121
32338873	32338895	13	-	27760321	MV411	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.523650211228161	[683,594]	[98,583]	-4	hSpCas9	negative selection	4549122
32338921	32338943	13	+	27760321	MV411	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	1.0828502685068042	[225,185]	[286,285]	7	hSpCas9	negative selection	4549123
32339025	32339047	13	-	27760321	MV411	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-1.0055553822293046	[204,178]	[18,128]	-6	hSpCas9	negative selection	4549124
32326495	32326517	13	-	27760321	HL60	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.2373385870395126	[468,461]	[370,272]	-3	hSpCas9	negative selection	4632583
32337864	32337886	13	-	27760321	HL60	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.37183612665331656	[545,438]	[363,250]	-4	hSpCas9	negative selection	4632584
32338873	32338895	13	-	27760321	HL60	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-1.004139034186631	[683,594]	[203,318]	-7	hSpCas9	negative selection	4632585
32338921	32338943	13	+	27760321	HL60	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	1.0688203779196728	[225,185]	[428,268]	9	hSpCas9	negative selection	4632586
32339025	32339047	13	-	27760321	HL60	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.020459368218043172	[204,178]	[146,161]	0	hSpCas9	negative selection	4632587
32326495	32326517	13	-	27760321	HT1080	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.14642925623892206	[461,360]	[118,179]	0	hSpCas9	negative selection	4716046
32337864	32337886	13	-	27760321	HT1080	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-1.3980239783155857	[438,342]	[92,21]	-5	hSpCas9	negative selection	4716047
32338873	32338895	13	-	27760321	HT1080	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.5253775261502622	[594,463]	[136,156]	-2	hSpCas9	negative selection	4716048
32338921	32338943	13	+	27760321	HT1080	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	-4.760591752492964	[185,144]	[0,3]	-8	hSpCas9	negative selection	4716049
32339025	32339047	13	-	27760321	HT1080	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.5604841999401562	[178,139]	[44,40]	-2	hSpCas9	negative selection	4716050
32326495	32326517	13	-	27760321	HT29	viability after 7 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.6539433968820351	[461,360]	[581,208,254]	-7	hSpCas9	negative selection	4799509
32337864	32337886	13	-	27760321	HT29	viability after 7 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.027625512076185993	[438,342]	[673,505,329]	0	hSpCas9	negative selection	4799510
32338873	32338895	13	-	27760321	HT29	viability after 7 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.36071836763672105	[594,463]	[954,410,291]	-5	hSpCas9	negative selection	4799511
32338921	32338943	13	+	27760321	HT29	viability after 7 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	-0.23288887996656005	[185,144]	[246,82,220]	-3	hSpCas9	negative selection	4799512
32339025	32339047	13	-	27760321	HT29	viability after 7 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	0.5157835170784023	[178,139]	[291,416,173]	7	hSpCas9	negative selection	4799513
32326495	32326517	13	-	27760321	HT29	viability after 25 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.3622606736360026	[461,360]	[200,140,207]	-7	hSpCas9	negative selection	4882972
32337864	32337886	13	-	27760321	HT29	viability after 25 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.4484707182891021	[438,342]	[374,275,327]	-4	hSpCas9	negative selection	4882973
32338873	32338895	13	-	27760321	HT29	viability after 25 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.38160143855451545	[594,463]	[298,562,549]	-4	hSpCas9	negative selection	4882974
32338921	32338943	13	+	27760321	HT29	viability after 25 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.44251668006622846	[185,144]	[297,273,188]	5	hSpCas9	negative selection	4882975
32339025	32339047	13	-	27760321	HT29	viability after 25 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	0.2240510354428794	[178,139]	[252,160,222]	2	hSpCas9	negative selection	4882976
32326495	32326517	13	-	27760321	HT29	viability after 22 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.1770426626310744	[461,360]	[350,107,167]	-7	hSpCas9	negative selection	4966435
32337864	32337886	13	-	27760321	HT29	viability after 22 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.6335375396487218	[438,342]	[245,376,251]	-5	hSpCas9	negative selection	4966436
32338873	32338895	13	-	27760321	HT29	viability after 22 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.392124840442597	[594,463]	[499,362,535]	-4	hSpCas9	negative selection	4966437
32338921	32338943	13	+	27760321	HT29	viability after 22 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.052270771122356674	[185,144]	[151,178,265]	0	hSpCas9	negative selection	4966438
32339025	32339047	13	-	27760321	HT29	viability after 22 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	0.4878982425330163	[178,139]	[334,262,174]	5	hSpCas9	negative selection	4966439
32326495	32326517	13	-	27760321	HT29	viability after 19 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.2875113509956504	[461,360]	[221,317,46]	-7	hSpCas9	negative selection	5049898
32337864	32337886	13	-	27760321	HT29	viability after 19 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.796106269758324	[438,342]	[364,275,146]	-6	hSpCas9	negative selection	5049899
32338873	32338895	13	-	27760321	HT29	viability after 19 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.4693563801380017	[594,463]	[540,459,325]	-4	hSpCas9	negative selection	5049900
32338921	32338943	13	+	27760321	HT29	viability after 19 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.1763669399808202	[185,144]	[131,208,288]	1	hSpCas9	negative selection	5049901
32339025	32339047	13	-	27760321	HT29	viability after 19 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.15089357890820798	[178,139]	[259,81,160]	-1	hSpCas9	negative selection	5049902
32326495	32326517	13	-	27760321	HT29	viability after 16 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.2653196867752274	[461,360]	[244,100,235]	-7	hSpCas9	negative selection	5133361
32337864	32337886	13	-	27760321	HT29	viability after 16 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.3346421972284906	[438,342]	[201,614,202]	-4	hSpCas9	negative selection	5133362
32338873	32338895	13	-	27760321	HT29	viability after 16 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.07917376991614655	[594,463]	[481,625,564]	-1	hSpCas9	negative selection	5133363
32338921	32338943	13	+	27760321	HT29	viability after 16 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.29658937898886717	[185,144]	[226,232,221]	3	hSpCas9	negative selection	5133364
32339025	32339047	13	-	27760321	HT29	viability after 16 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	-0.034289534235845354	[178,139]	[103,180,230]	0	hSpCas9	negative selection	5133365
32326495	32326517	13	-	27760321	HT29	viability after 13 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-1.2764738636266895	[461,360]	[336,75,178]	-8	hSpCas9	negative selection	5216824
32337864	32337886	13	-	27760321	HT29	viability after 13 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-0.2482167368745764	[438,342]	[360,474,313]	-3	hSpCas9	negative selection	5216825
32338873	32338895	13	-	27760321	HT29	viability after 13 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.032845467727077415	[594,463]	[512,681,605]	0	hSpCas9	negative selection	5216826
32338921	32338943	13	+	27760321	HT29	viability after 13 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	0.05377898362177724	[185,144]	[245,208,145]	0	hSpCas9	negative selection	5216827
32339025	32339047	13	-	27760321	HT29	viability after 13 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	0.5387522720217209	[178,139]	[225,318,261]	7	hSpCas9	negative selection	5216828
32326495	32326517	13	-	27760321	HT29	viability after 10 days	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	-0.5954546055342915	[461,360]	[424,118,466]	-6	hSpCas9	negative selection	5300287
32337864	32337886	13	-	27760321	HT29	viability after 10 days	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	0.2323636395627497	[438,342]	[576,761,390]	3	hSpCas9	negative selection	5300288
32338873	32338895	13	-	27760321	HT29	viability after 10 days	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	0.0017142876429427911	[594,463]	[608,715,661]	0	hSpCas9	negative selection	5300289
32338921	32338943	13	+	27760321	HT29	viability after 10 days	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	-0.07831647139980413	[185,144]	[280,175,130]	-1	hSpCas9	negative selection	5300290
32339025	32339047	13	-	27760321	HT29	viability after 10 days	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	0.3448474138021532	[178,139]	[254,315,190]	4	hSpCas9	negative selection	5300291
32326495	32326517	13	-	27760321	MOLM13	viability	TTTTGGTGTCTGACGACCCTGG	BRCA2	ENSG00000139618	0.0876383419729586	[468,461]	[530,65]	0	hSpCas9	negative selection	5383750
32337864	32337886	13	-	27760321	MOLM13	viability	TCTACCTGACCAATCGATGGGG	BRCA2	ENSG00000139618	-1.1388282763500697	[545,438]	[71,170]	-6	hSpCas9	negative selection	5383751
32338873	32338895	13	-	27760321	MOLM13	viability	ATCACGTTCGGGTTGTCCCTGG	BRCA2	ENSG00000139618	-0.5689646115740095	[683,594]	[287,203]	-4	hSpCas9	negative selection	5383752
32338921	32338943	13	+	27760321	MOLM13	viability	GGGTTTTCATACAGCTAGCGGG	BRCA2	ENSG00000139618	-0.5040176685380422	[225,185]	[46,110]	-3	hSpCas9	negative selection	5383753
32339025	32339047	13	-	27760321	MOLM13	viability	GCCCATTGATGGCTAAAACTGG	BRCA2	ENSG00000139618	1.5214053284555948	[204,178]	[30,547]	9	hSpCas9	negative selection	5383754
32315897	32315920	13	-	27661255	K562	viability	GAGCTGAAGGCGGAGCCCAAAGG	BRCA2	ENSG00000139618	-0.8526411635498093	[1710,1776]	[825,723]	-8	dCas9-KRAB	negative selection	5465468
32337866	32337889	13	-	27260156	BXPC3	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.5231061494379272	[132]	[200,224,142,229]	9	hSpCas9	negative selection	5530925
32340091	32340114	13	+	27260156	BXPC3	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.0059207079754592384	[335]	[218,434,398,367]	0	hSpCas9	negative selection	5530926
32346875	32346898	13	+	27260156	BXPC3	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.23693585150289342	[1455]	[1596,1822,1704,2093]	5	hSpCas9	negative selection	5530927
32346881	32346904	13	-	27260156	BXPC3	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.26598414976806606	[699]	[548,578,648,669]	-6	hSpCas9	negative selection	5595209
32344579	32344602	13	+	27260156	BXPC3	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.05135220227370085	[698]	[527,721,880,706]	-1	hSpCas9	negative selection	5595210
32344610	32344633	13	+	27260156	BXPC3	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.29332594803053824	[265]	[376,256,319,416]	6	hSpCas9	negative selection	5595211
32337866	32337889	13	-	27260156	A673	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.42129698033999485	[132]	[136,89,139,111]	-8	hSpCas9	negative selection	5652176
32340091	32340114	13	+	27260156	A673	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.2085512879662324	[335]	[415,285,283,423]	-5	hSpCas9	negative selection	5652177
32346875	32346898	13	+	27260156	A673	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.040470662236864685	[1455]	[2029,1585,1742,1865]	1	hSpCas9	negative selection	5652178
32346881	32346904	13	-	27260156	A673	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3634034256683334	[699]	[692,655,686,575]	-7	hSpCas9	negative selection	5716460
32344579	32344602	13	+	27260156	A673	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.295004355250679	[698]	[695,749,566,724]	-6	hSpCas9	negative selection	5716461
32344610	32344633	13	+	27260156	A673	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.05741388330242614	[265]	[341,324,229,439]	1	hSpCas9	negative selection	5716462
32337866	32337889	13	-	27260156	A375	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.3515337579821898	[132]	[56,84,65,40]	-9	hSpCas9	negative selection	5773427
32340091	32340114	13	+	27260156	A375	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.2166134572844427	[335]	[340,697,626,217]	3	hSpCas9	negative selection	5773428
32346875	32346898	13	+	27260156	A375	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.4415527128726615	[1455]	[2306,3287,2115,1724]	6	hSpCas9	negative selection	5773429
32346881	32346904	13	-	27260156	A375	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.4821813307709669	[699]	[404,712,823,431]	-6	hSpCas9	negative selection	5837711
32344579	32344602	13	+	27260156	A375	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.06192372395026091	[698]	[660,1380,733,717]	0	hSpCas9	negative selection	5837712
32344610	32344633	13	+	27260156	A375	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.5235210190919524	[265]	[417,401,490,464]	7	hSpCas9	negative selection	5837713
32337866	32337889	13	-	27260156	COLO741	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.22362560815584276	[132]	[120,219,96]	-5	hSpCas9	negative selection	5894678
32340091	32340114	13	+	27260156	COLO741	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.05459864254631114	[335]	[354,502,378]	-1	hSpCas9	negative selection	5894679
32346875	32346898	13	+	27260156	COLO741	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.03593485118005013	[1455]	[2043,1835,1852]	0	hSpCas9	negative selection	5894680
32346881	32346904	13	-	27260156	COLO741	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3235713580878378	[699]	[697,684,754]	-6	hSpCas9	negative selection	5958962
32344579	32344602	13	+	27260156	COLO741	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.036209202449330236	[698]	[633,885,1056]	0	hSpCas9	negative selection	5958963
32344610	32344633	13	+	27260156	COLO741	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.09400909581692762	[265]	[335,424,326]	2	hSpCas9	negative selection	5958964
32337866	32337889	13	-	27260156	CAL120	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.034194930429599	[132]	[92,56,93]	-8	hSpCas9	negative selection	6015929
32340091	32340114	13	+	27260156	CAL120	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.2650692046135219	[335]	[456,356,682]	4	hSpCas9	negative selection	6015930
32346875	32346898	13	+	27260156	CAL120	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.43047105333304314	[1455]	[3163,1999,2271]	6	hSpCas9	negative selection	6015931
32346881	32346904	13	-	27260156	CAL120	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.5623428620426013	[699]	[762,527,505]	-7	hSpCas9	negative selection	6080213
32344579	32344602	13	+	27260156	CAL120	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.06570776372419296	[698]	[1005,834,680]	-1	hSpCas9	negative selection	6080214
32344610	32344633	13	+	27260156	CAL120	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.4158323869931797	[265]	[389,327,595]	6	hSpCas9	negative selection	6080215
32337866	32337889	13	-	27260156	CADOES1	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.40133533007925637	[132]	[54,68,173,75]	-6	hSpCas9	negative selection	6137180
32340091	32340114	13	+	27260156	CADOES1	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.08633447523456844	[335]	[310,252,248,366]	-1	hSpCas9	negative selection	6137181
32346875	32346898	13	+	27260156	CADOES1	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	-0.049910538654079684	[1455]	[1181,1329,1356,1365]	-1	hSpCas9	negative selection	6137182
32346881	32346904	13	-	27260156	CADOES1	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3183006664999517	[699]	[574,549,479,481]	-5	hSpCas9	negative selection	6201464
32344579	32344602	13	+	27260156	CADOES1	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.1881323685509838	[698]	[621,707,811,823]	3	hSpCas9	negative selection	6201465
32344610	32344633	13	+	27260156	CADOES1	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6876651850578734	[265]	[302,361,403,529]	9	hSpCas9	negative selection	6201466
32337866	32337889	13	-	27260156	EWS502	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.3633040299572454	[132]	[111,99,112,112]	-6	hSpCas9	negative selection	6258431
32340091	32340114	13	+	27260156	EWS502	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.3095944251337672	[335]	[357,514,452,443]	5	hSpCas9	negative selection	6258432
32346875	32346898	13	+	27260156	EWS502	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.1869557981403258	[1455]	[1554,1824,1804,1859]	3	hSpCas9	negative selection	6258433
32346881	32346904	13	-	27260156	EWS502	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.8973036323737891	[699]	[335,281,422,574]	-8	hSpCas9	negative selection	6322715
32344579	32344602	13	+	27260156	EWS502	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.04306851943527534	[698]	[703,679,831,655]	-1	hSpCas9	negative selection	6322716
32344610	32344633	13	+	27260156	EWS502	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6620094925671295	[265]	[328,425,493,555]	9	hSpCas9	negative selection	6322717
32337866	32337889	13	-	27260156	EW8	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.020547988971043818	[132]	[102,74,130,110]	0	hSpCas9	negative selection	6379682
32340091	32340114	13	+	27260156	EW8	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.32115877676701854	[335]	[497,366,254,271]	6	hSpCas9	negative selection	6379683
32346875	32346898	13	+	27260156	EW8	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.41792728114443234	[1455]	[2218,1497,1324,1372]	7	hSpCas9	negative selection	6379684
32346881	32346904	13	-	27260156	EW8	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.37917822471403184	[699]	[510,275,487,466]	-6	hSpCas9	negative selection	6443966
32344579	32344602	13	+	27260156	EW8	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.3382733822941102	[698]	[713,582,603,978]	6	hSpCas9	negative selection	6443967
32344610	32344633	13	+	27260156	EW8	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.4814787814508171	[265]	[182,383,290,333]	8	hSpCas9	negative selection	6443968
32337866	32337889	13	-	27260156	CORL105	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.5271917603227818	[132]	[111,60,82,172]	-7	hSpCas9	negative selection	6500933
32340091	32340114	13	+	27260156	CORL105	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.0010174465610148231	[335]	[343,382,495,365]	0	hSpCas9	negative selection	6500934
32346875	32346898	13	+	27260156	CORL105	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.1456801897007567	[1455]	[2007,1738,1961,1851]	2	hSpCas9	negative selection	6500935
32346881	32346904	13	-	27260156	CORL105	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.9350889456257173	[699]	[473,355,402,479]	-9	hSpCas9	negative selection	6565217
32344579	32344602	13	+	27260156	CORL105	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.13121525920614951	[698]	[777,686,768,759]	-2	hSpCas9	negative selection	6565218
32344610	32344633	13	+	27260156	CORL105	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.5462476366419368	[265]	[477,360,728,296]	8	hSpCas9	negative selection	6565219
32337866	32337889	13	-	27260156	HS294T	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.0070350469164522	[132]	[17,17,22,47]	-9	hSpCas9	negative selection	6622184
32340091	32340114	13	+	27260156	HS294T	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.34730474659730415	[335]	[123,194,186,155]	4	hSpCas9	negative selection	6622185
32346875	32346898	13	+	27260156	HS294T	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.5428210815315495	[1455]	[682,828,867,928]	7	hSpCas9	negative selection	6622186
32346881	32346904	13	-	27260156	HS294T	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.5401862296856869	[699]	[175,166,173,236]	-6	hSpCas9	negative selection	6686468
32344579	32344602	13	+	27260156	HS294T	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.25353037408449747	[698]	[226,224,177,285]	-4	hSpCas9	negative selection	6686469
32344610	32344633	13	+	27260156	HS294T	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	-0.36922751425027267	[265]	[81,95,51,88]	-5	hSpCas9	negative selection	6686470
32337866	32337889	13	-	27260156	HCC44	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.12066440433166226	[132]	[55,152,283,171]	2	hSpCas9	negative selection	6743435
32340091	32340114	13	+	27260156	HCC44	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.11899080881572355	[335]	[391,257,651,406]	1	hSpCas9	negative selection	6743436
32346875	32346898	13	+	27260156	HCC44	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.37481383158075765	[1455]	[2187,1998,2251,2128]	6	hSpCas9	negative selection	6743437
32346881	32346904	13	-	27260156	HCC44	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.2132705084894086	[699]	[570,436,1035,764]	-3	hSpCas9	negative selection	6807719
32344579	32344602	13	+	27260156	HCC44	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.09044332700192559	[698]	[628,809,1168,794]	1	hSpCas9	negative selection	6807720
32344610	32344633	13	+	27260156	HCC44	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6731592638512538	[265]	[827,201,667,325]	9	hSpCas9	negative selection	6807721
32337866	32337889	13	-	27260156	G402	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.017943830670239524	[132]	[35,233,246,126]	0	hSpCas9	negative selection	6864686
32340091	32340114	13	+	27260156	G402	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.03248322810129112	[335]	[372,602,206,492]	0	hSpCas9	negative selection	6864687
32346875	32346898	13	+	27260156	G402	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.5071017216197244	[1455]	[2651,2737,1981,2737]	6	hSpCas9	negative selection	6864688
32346881	32346904	13	-	27260156	G402	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.7155384274719914	[699]	[683,686,560,195]	-7	hSpCas9	negative selection	6928970
32344579	32344602	13	+	27260156	G402	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.3987669328456621	[698]	[1344,1104,1304,785]	5	hSpCas9	negative selection	6928971
32344610	32344633	13	+	27260156	G402	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6109963196629409	[265]	[529,276,665,499]	7	hSpCas9	negative selection	6928972
32337866	32337889	13	-	27260156	L33	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.11471360091348126	[132]	[115,45,84,127]	-3	hSpCas9	negative selection	6985937
32340091	32340114	13	+	27260156	L33	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.3518114970639852	[335]	[468,171,241,439]	7	hSpCas9	negative selection	6985938
32346875	32346898	13	+	27260156	L33	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.3214828124413076	[1455]	[1862,691,1255,1727]	6	hSpCas9	negative selection	6985939
32346881	32346904	13	-	27260156	L33	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.18355599716758936	[699]	[624,282,285,692]	-4	hSpCas9	negative selection	7050221
32344579	32344602	13	+	27260156	L33	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.10280870408577181	[698]	[575,247,442,718]	-2	hSpCas9	negative selection	7050222
32344610	32344633	13	+	27260156	L33	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.2525402495674307	[265]	[283,147,185,326]	5	hSpCas9	negative selection	7050223
32337866	32337889	13	-	27260156	K562	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.6100050813027695	[132]	[196,271,57,196]	7	hSpCas9	negative selection	7107188
32340091	32340114	13	+	27260156	K562	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.9866291141928145	[335]	[620,628,558,559]	9	hSpCas9	negative selection	7107189
32346875	32346898	13	+	27260156	K562	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.2548950291046672	[1455]	[1221,2008,1235,1675]	3	hSpCas9	negative selection	7107190
32346881	32346904	13	-	27260156	K562	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.013772267550564488	[699]	[1212,381,593,338]	0	hSpCas9	negative selection	7171472
32344579	32344602	13	+	27260156	K562	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.12813124358332828	[698]	[1049,666,591,455]	1	hSpCas9	negative selection	7171473
32344610	32344633	13	+	27260156	K562	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	1.0639720840394409	[265]	[259,527,666,498]	9	hSpCas9	negative selection	7171474
32337866	32337889	13	-	27260156	HT29	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.4658243490171978	[132]	[133,96,154,84]	-7	hSpCas9	negative selection	7228439
32340091	32340114	13	+	27260156	HT29	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.12676251232911245	[335]	[243,501,404,346]	-3	hSpCas9	negative selection	7228440
32346875	32346898	13	+	27260156	HT29	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.23475661321051877	[1455]	[2059,2487,2232,1624]	4	hSpCas9	negative selection	7228441
32346881	32346904	13	-	27260156	HT29	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.46424899512012396	[699]	[585,684,576,617]	-7	hSpCas9	negative selection	7292723
32344579	32344602	13	+	27260156	HT29	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.1720368474317261	[698]	[1012,926,1150,757]	3	hSpCas9	negative selection	7292724
32344610	32344633	13	+	27260156	HT29	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.42302071452442846	[265]	[447,482,386,419]	7	hSpCas9	negative selection	7292725
32337866	32337889	13	-	27260156	MHHES1	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.6177652124149033	[132]	[122,51,74,128]	-8	hSpCas9	negative selection	7349690
32340091	32340114	13	+	27260156	MHHES1	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.20673096532884655	[335]	[369,533,542,319]	4	hSpCas9	negative selection	7349691
32346875	32346898	13	+	27260156	MHHES1	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.024595895652458122	[1455]	[1998,1706,1610,1418]	0	hSpCas9	negative selection	7349692
32346881	32346904	13	-	27260156	MHHES1	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.7200789321183169	[699]	[287,525,548,513]	-8	hSpCas9	negative selection	7413974
32344579	32344602	13	+	27260156	MHHES1	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.003199693085615518	[698]	[823,905,675,754]	0	hSpCas9	negative selection	7413975
32344610	32344633	13	+	27260156	MHHES1	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.12978491990140995	[265]	[437,433,276,206]	2	hSpCas9	negative selection	7413976
32337866	32337889	13	-	27260156	MEWO	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.707025940323093	[132]	[97,49,84]	-8	hSpCas9	negative selection	7470941
32340091	32340114	13	+	27260156	MEWO	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.06304550447166307	[335]	[286,292,319]	-1	hSpCas9	negative selection	7470942
32346875	32346898	13	+	27260156	MEWO	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.10715821391494007	[1455]	[1864,1336,1276]	2	hSpCas9	negative selection	7470943
32346881	32346904	13	-	27260156	MEWO	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.4051797156250961	[699]	[455,501,517]	-7	hSpCas9	negative selection	7535225
32344579	32344602	13	+	27260156	MEWO	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.21295108564321763	[698]	[635,446,623]	-5	hSpCas9	negative selection	7535226
32344610	32344633	13	+	27260156	MEWO	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.25731776181879396	[265]	[391,215,302]	5	hSpCas9	negative selection	7535227
32337866	32337889	13	-	27260156	LNCAPCLONEFGC	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.4454337055897848	[132]	[56,59,220,37]	-6	hSpCas9	negative selection	7592192
32340091	32340114	13	+	27260156	LNCAPCLONEFGC	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.11423117192527932	[335]	[306,328,335,346]	1	hSpCas9	negative selection	7592193
32346875	32346898	13	+	27260156	LNCAPCLONEFGC	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.47155446303173276	[1455]	[1931,1698,2201,1542]	7	hSpCas9	negative selection	7592194
32346881	32346904	13	-	27260156	LNCAPCLONEFGC	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.5447633660842278	[699]	[579,404,430,320]	-7	hSpCas9	negative selection	7656476
32344579	32344602	13	+	27260156	LNCAPCLONEFGC	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.011031459006632605	[698]	[633,567,675,645]	0	hSpCas9	negative selection	7656477
32344610	32344633	13	+	27260156	LNCAPCLONEFGC	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.777225398298471	[265]	[388,482,288,467]	9	hSpCas9	negative selection	7656478
32337866	32337889	13	-	27260156	PANC0327	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.6270806326251301	[132]	[174,259,77,205]	8	hSpCas9	negative selection	7713443
32340091	32340114	13	+	27260156	PANC0327	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.043482791270675836	[335]	[357,235,443,205]	0	hSpCas9	negative selection	7713444
32346875	32346898	13	+	27260156	PANC0327	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.4057387769161491	[1455]	[1613,1361,2109,1804]	6	hSpCas9	negative selection	7713445
32346881	32346904	13	-	27260156	PANC0327	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.7196846643033515	[699]	[320,552,360,247]	-7	hSpCas9	negative selection	7777727
32344579	32344602	13	+	27260156	PANC0327	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.008244362289512419	[698]	[584,541,590,786]	0	hSpCas9	negative selection	7777728
32344610	32344633	13	+	27260156	PANC0327	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.5212125290457885	[265]	[414,274,401,278]	7	hSpCas9	negative selection	7777729
32337866	32337889	13	-	27260156	NCIH2009	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.5524501122919885	[132]	[66,76,224]	-6	hSpCas9	negative selection	7834694
32340091	32340114	13	+	27260156	NCIH2009	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.19447337440528845	[335]	[552,524,535]	2	hSpCas9	negative selection	7834695
32346875	32346898	13	+	27260156	NCIH2009	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.3981502671489885	[1455]	[3499,2334,2370]	5	hSpCas9	negative selection	7834696
32346881	32346904	13	-	27260156	NCIH2009	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-1.0129813864054706	[699]	[418,488,531]	-8	hSpCas9	negative selection	7898978
32344579	32344602	13	+	27260156	NCIH2009	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.27073436750467733	[698]	[976,713,770]	-4	hSpCas9	negative selection	7898979
32344610	32344633	13	+	27260156	NCIH2009	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.17819551691629343	[265]	[432,379,450]	2	hSpCas9	negative selection	7898980
32337866	32337889	13	-	27260156	NCIH1373	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.16915844730069218	[132]	[173,35,180,40]	-2	hSpCas9	negative selection	7955945
32340091	32340114	13	+	27260156	NCIH1373	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.06047807253538168	[335]	[363,455,291,83]	0	hSpCas9	negative selection	7955946
32346875	32346898	13	+	27260156	NCIH1373	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.5842679027823308	[1455]	[2814,2593,1783,695]	6	hSpCas9	negative selection	7955947
32346881	32346904	13	-	27260156	NCIH1373	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.480742688806342	[699]	[685,589,439,143]	-5	hSpCas9	negative selection	8020229
32344579	32344602	13	+	27260156	NCIH1373	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.46657208459262733	[698]	[1258,989,686,382]	4	hSpCas9	negative selection	8020230
32344610	32344633	13	+	27260156	NCIH1373	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6754322258622403	[265]	[641,501,329,118]	6	hSpCas9	negative selection	8020231
32337866	32337889	13	-	27260156	PATU8902	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.745606536261842	[132]	[76,208,93,59]	-6	hSpCas9	negative selection	8077196
32340091	32340114	13	+	27260156	PATU8902	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.2814304532000972	[335]	[458,775,433,647]	3	hSpCas9	negative selection	8077197
32346875	32346898	13	+	27260156	PATU8902	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.5045055663008626	[1455]	[2969,1762,3167,3586]	5	hSpCas9	negative selection	8077198
32346881	32346904	13	-	27260156	PATU8902	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.5821609708171266	[699]	[517,784,537,808]	-5	hSpCas9	negative selection	8141480
32344579	32344602	13	+	27260156	PATU8902	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.1873301871181633	[698]	[1432,1123,803,1142]	2	hSpCas9	negative selection	8141481
32344610	32344633	13	+	27260156	PATU8902	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.40608730291610673	[265]	[577,469,241,765]	4	hSpCas9	negative selection	8141482
32337866	32337889	13	-	27260156	PANC1	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.42799835217860727	[132]	[177,89,33,41]	-6	hSpCas9	negative selection	8198447
32340091	32340114	13	+	27260156	PANC1	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.02793380400677986	[335]	[223,256,419,269]	0	hSpCas9	negative selection	8198448
32346875	32346898	13	+	27260156	PANC1	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.21092728946952333	[1455]	[1191,2147,1479,1145]	3	hSpCas9	negative selection	8198449
32346881	32346904	13	-	27260156	PANC1	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.1697958365168738	[699]	[612,618,566,372]	-3	hSpCas9	negative selection	8262731
32344579	32344602	13	+	27260156	PANC1	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.16855656689981968	[698]	[636,787,853,468]	2	hSpCas9	negative selection	8262732
32344610	32344633	13	+	27260156	PANC1	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.690486150322693	[265]	[347,251,516,334]	9	hSpCas9	negative selection	8262733
32337866	32337889	13	-	27260156	PANC0813	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	0.25280106153439896	[132]	[131,156,252,196]	4	hSpCas9	negative selection	8319698
32340091	32340114	13	+	27260156	PANC0813	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.9028647525581703	[335]	[791,806,703,656]	9	hSpCas9	negative selection	8319699
32346875	32346898	13	+	27260156	PANC0813	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.39632316792120914	[1455]	[2398,2547,2009,2065]	6	hSpCas9	negative selection	8319700
32346881	32346904	13	-	27260156	PANC0813	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.64309111440914	[699]	[504,691,457,451]	-7	hSpCas9	negative selection	8383982
32344579	32344602	13	+	27260156	PANC0813	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.24776209960458395	[698]	[837,668,683,592]	-4	hSpCas9	negative selection	8383983
32344610	32344633	13	+	27260156	PANC0813	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.5471149923185903	[265]	[524,504,392,410]	8	hSpCas9	negative selection	8383984
32337866	32337889	13	-	27260156	RDES	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.35179002462389963	[132]	[97,79,197,109]	-6	hSpCas9	negative selection	8440949
32340091	32340114	13	+	27260156	RDES	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.2895742866519448	[335]	[398,546,434,504]	4	hSpCas9	negative selection	8440950
32346875	32346898	13	+	27260156	RDES	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.36967828764833	[1455]	[1716,1988,2419,2662]	6	hSpCas9	negative selection	8440951
32346881	32346904	13	-	27260156	RDES	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3378777422958352	[699]	[551,601,799,594]	-5	hSpCas9	negative selection	8505233
32344579	32344602	13	+	27260156	RDES	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.09368445128663927	[698]	[701,800,850,1131]	1	hSpCas9	negative selection	8505234
32344610	32344633	13	+	27260156	RDES	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.3390263455297594	[265]	[376,347,292,542]	5	hSpCas9	negative selection	8505235
32337866	32337889	13	-	27260156	PC3	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.22664491653795293	[132]	[38,151,153,148]	-5	hSpCas9	negative selection	8562200
32340091	32340114	13	+	27260156	PC3	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.029513774144368565	[335]	[204,299,550,368]	0	hSpCas9	negative selection	8562201
32346875	32346898	13	+	27260156	PC3	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.18890057736585053	[1455]	[976,1629,2863,1767]	4	hSpCas9	negative selection	8562202
32346881	32346904	13	-	27260156	PC3	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.2844032800790139	[699]	[445,443,970,581]	-6	hSpCas9	negative selection	8626484
32344579	32344602	13	+	27260156	PC3	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.14976258532693676	[698]	[398,775,806,627]	-3	hSpCas9	negative selection	8626485
32344610	32344633	13	+	27260156	PC3	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.0956400653274081	[265]	[136,295,367,411]	2	hSpCas9	negative selection	8626486
32337866	32337889	13	-	27260156	PATU8988T	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-1.276671327604069	[132]	[43,28,58,79]	-9	hSpCas9	negative selection	8683451
32340091	32340114	13	+	27260156	PATU8988T	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.14606968234098422	[335]	[279,314,576,248]	2	hSpCas9	negative selection	8683452
32346875	32346898	13	+	27260156	PATU8988T	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.10178683448175874	[1455]	[1251,1767,1480,1566]	1	hSpCas9	negative selection	8683453
32346881	32346904	13	-	27260156	PATU8988T	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-1.0894552944010476	[699]	[327,297,290,355]	-9	hSpCas9	negative selection	8747735
32344579	32344602	13	+	27260156	PATU8988T	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.17195583481026555	[698]	[934,749,714,632]	3	hSpCas9	negative selection	8747736
32344610	32344633	13	+	27260156	PATU8988T	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.2732910514886896	[265]	[319,308,326,283]	5	hSpCas9	negative selection	8747737
32337866	32337889	13	-	27260156	T47D	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.5257824434674969	[132]	[105,91,115,117]	-8	hSpCas9	negative selection	8804702
32340091	32340114	13	+	27260156	T47D	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.21922256599255446	[335]	[422,451,392,558]	4	hSpCas9	negative selection	8804703
32346875	32346898	13	+	27260156	T47D	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.20955906657916223	[1455]	[2084,1716,2111,1949]	4	hSpCas9	negative selection	8804704
32346881	32346904	13	-	27260156	T47D	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.4183889918837037	[699]	[634,494,610,712]	-7	hSpCas9	negative selection	8868986
32344579	32344602	13	+	27260156	T47D	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.014524834842696954	[698]	[743,647,899,948]	0	hSpCas9	negative selection	8868987
32344610	32344633	13	+	27260156	T47D	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.4057984467346825	[265]	[398,454,387,395]	8	hSpCas9	negative selection	8868988
32337866	32337889	13	-	27260156	SU8686	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.6513911831156163	[132]	[63,60,81,142]	-7	hSpCas9	negative selection	8925953
32340091	32340114	13	+	27260156	SU8686	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.7502746340972677	[335]	[501,300,786,719]	9	hSpCas9	negative selection	8925954
32346875	32346898	13	+	27260156	SU8686	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.5566430617982596	[1455]	[1815,1914,2279,2611]	8	hSpCas9	negative selection	8925955
32346881	32346904	13	-	27260156	SU8686	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.7114243431990842	[699]	[472,350,496,367]	-8	hSpCas9	negative selection	8990237
32344579	32344602	13	+	27260156	SU8686	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.0697593534728248	[698]	[676,538,648,808]	-1	hSpCas9	negative selection	8990238
32344610	32344633	13	+	27260156	SU8686	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.3938686082043237	[265]	[333,296,410,351]	6	hSpCas9	negative selection	8990239
32337866	32337889	13	-	27260156	SKES1	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.27207383495181503	[132]	[209,60,118,61]	-5	hSpCas9	negative selection	9047204
32340091	32340114	13	+	27260156	SKES1	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.12699259387176537	[335]	[565,366,301,265]	2	hSpCas9	negative selection	9047205
32346875	32346898	13	+	27260156	SKES1	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.08039510668659688	[1455]	[1865,1662,1441,1251]	1	hSpCas9	negative selection	9047206
32346881	32346904	13	-	27260156	SKES1	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.017805185630073717	[699]	[575,688,837,636]	0	hSpCas9	negative selection	9111488
32344579	32344602	13	+	27260156	SKES1	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.048852727966975484	[698]	[683,822,546,657]	-1	hSpCas9	negative selection	9111489
32344610	32344633	13	+	27260156	SKES1	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.4835504583161166	[265]	[437,525,293,263]	8	hSpCas9	negative selection	9111490
32337866	32337889	13	-	27260156	TOV112D	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.529608599960592	[132]	[89,99,172,9]	-8	hSpCas9	negative selection	9168455
32340091	32340114	13	+	27260156	TOV112D	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	0.06673057500295881	[335]	[376,421,370,260]	1	hSpCas9	negative selection	9168456
32346875	32346898	13	+	27260156	TOV112D	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.18141672873412706	[1455]	[1788,1890,1358,1642]	3	hSpCas9	negative selection	9168457
32346881	32346904	13	-	27260156	TOV112D	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3785882049072141	[699]	[691,618,386,491]	-6	hSpCas9	negative selection	9232739
32344579	32344602	13	+	27260156	TOV112D	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.23793318161076454	[698]	[648,625,654,459]	-5	hSpCas9	negative selection	9232740
32344610	32344633	13	+	27260156	TOV112D	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.38404034919539715	[265]	[346,342,427,272]	7	hSpCas9	negative selection	9232741
32337866	32337889	13	-	27260156	TC71	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.0056409000643398155	[132]	[157,167,140,97]	0	hSpCas9	negative selection	9289706
32340091	32340114	13	+	27260156	TC71	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.07740282255782333	[335]	[295,392,341,334]	-2	hSpCas9	negative selection	9289707
32346875	32346898	13	+	27260156	TC71	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.13786080776481802	[1455]	[1781,1551,1695,1845]	3	hSpCas9	negative selection	9289708
32346881	32346904	13	-	27260156	TC71	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.3306335211078711	[699]	[721,583,489,590]	-7	hSpCas9	negative selection	9353990
32344579	32344602	13	+	27260156	TC71	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	-0.09215889044618514	[698]	[606,770,719,715]	-2	hSpCas9	negative selection	9353991
32344610	32344633	13	+	27260156	TC71	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.5414220596119715	[265]	[422,454,370,411]	9	hSpCas9	negative selection	9353992
32337866	32337889	13	-	27260156	TC32	viability	CTGTCTACCTGACCAATCGATGG	BRCA2	ENSG00000139618	-0.7017424542339135	[132]	[91,30,99,100]	-8	hSpCas9	negative selection	9410957
32340091	32340114	13	+	27260156	TC32	viability	ATGTAGCACGCATTCACATAAGG	BRCA2	ENSG00000139618	-0.03242806615726873	[335]	[276,278,387,299]	0	hSpCas9	negative selection	9410958
32346875	32346898	13	+	27260156	TC32	viability	CGATTACCTGTGTACCCTTTCGG	BRCA2	ENSG00000139618	0.13251311038887081	[1455]	[1297,1184,2006,1661]	2	hSpCas9	negative selection	9410959
32346881	32346904	13	-	27260156	TC32	viability	GTCTTACCGAAAGGGTACACAGG	BRCA2	ENSG00000139618	-0.07729956923745318	[699]	[531,505,942,584]	-1	hSpCas9	negative selection	9475241
32344579	32344602	13	+	27260156	TC32	viability	ACTTATTAAATGAATTTGACAGG	BRCA2	ENSG00000139618	0.05558686427073367	[698]	[589,443,1090,743]	1	hSpCas9	negative selection	9475242
32344610	32344633	13	+	27260156	TC32	viability	AAATCAAGAAAAATCCTTAAAGG	BRCA2	ENSG00000139618	0.6202039931770575	[265]	[304,283,559,447]	9	hSpCas9	negative selection	9475243
32316506	32316529	13	+	27869803	HPAFII	viability after 27 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-3.794885570095388	[179]	[8,4,NaN]	-9	hSpCas9	negative selection	9549665
32326587	32326610	13	-	27869803	HPAFII	viability after 27 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.7608380892677102	[200]	[9,105,NaN]	-5	hSpCas9	negative selection	9549666
32333077	32333100	13	+	27869803	HPAFII	viability after 27 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.8239833460573526	[163]	[42,243,NaN]	6	hSpCas9	negative selection	9549667
32339876	32339899	13	-	27869803	HPAFII	viability after 27 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.7429201985711613	[348]	[59,150,NaN]	-5	hSpCas9	negative selection	9549668
32356493	32356516	13	+	27869803	HPAFII	viability after 27 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.16801611764030822	[189]	[191,2,NaN]	-1	hSpCas9	negative selection	9549669
32357889	32357912	13	+	27869803	HPAFII	viability after 27 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-1.3520106939541987	[289]	[110,16,NaN]	-7	hSpCas9	negative selection	9549670
32316506	32316529	13	+	27869803	HPAFII	viability after 15 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-2.355432134569574	[179]	[59,23,NaN]	-9	hSpCas9	negative selection	9632114
32326587	32326610	13	-	27869803	HPAFII	viability after 15 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.0184746415521277	[200]	[134,88,NaN]	-7	hSpCas9	negative selection	9632115
32333077	32333100	13	+	27869803	HPAFII	viability after 15 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.41054759869525137	[163]	[171,272,NaN]	5	hSpCas9	negative selection	9632116
32339876	32339899	13	-	27869803	HPAFII	viability after 15 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.6093617961264468	[348]	[354,177,NaN]	-6	hSpCas9	negative selection	9632117
32356493	32356516	13	+	27869803	HPAFII	viability after 15 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.23161903371589387	[189]	[295,97,NaN]	-3	hSpCas9	negative selection	9632118
32357889	32357912	13	+	27869803	HPAFII	viability after 15 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.06896361982797572	[289]	[544,142,NaN]	0	hSpCas9	negative selection	9632119
32316506	32316529	13	+	27869803	ASPC1	viability after 36 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.1899499933654048	[538]	[22,391,205]	1	hSpCas9	negative selection	9714563
32326587	32326610	13	-	27869803	ASPC1	viability after 36 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	0.3289295033009779	[417]	[74,160,274]	3	hSpCas9	negative selection	9714564
32333077	32333100	13	+	27869803	ASPC1	viability after 36 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.9246182932292417	[381]	[384,281,134]	8	hSpCas9	negative selection	9714565
32339876	32339899	13	-	27869803	ASPC1	viability after 36 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	0.82758157730387	[741]	[1051,226,223]	7	hSpCas9	negative selection	9714566
32356493	32356516	13	+	27869803	ASPC1	viability after 36 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.5893684528485651	[584]	[255,54,113]	-5	hSpCas9	negative selection	9714567
32357889	32357912	13	+	27869803	ASPC1	viability after 36 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.973524246924245	[537]	[140,107,52]	-7	hSpCas9	negative selection	9714568
32316506	32316529	13	+	27869803	PATU8988S	viability after 35 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-0.27377579141639874	[287]	[70,120,NaN]	-3	hSpCas9	negative selection	9797012
32326587	32326610	13	-	27869803	PATU8988S	viability after 35 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.0010113519313253	[476]	[90,100,NaN]	-7	hSpCas9	negative selection	9797013
32333077	32333100	13	+	27869803	PATU8988S	viability after 35 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	1.2262858009348674	[244]	[169,291,NaN]	9	hSpCas9	negative selection	9797014
32339876	32339899	13	-	27869803	PATU8988S	viability after 35 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.8965629726019873	[671]	[93,196,NaN]	-7	hSpCas9	negative selection	9797015
32356493	32356516	13	+	27869803	PATU8988S	viability after 35 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.02396295846658658	[465]	[223,144,NaN]	0	hSpCas9	negative selection	9797016
32357889	32357912	13	+	27869803	PATU8988S	viability after 35 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	0.14860578547558712	[527]	[333,136,NaN]	1	hSpCas9	negative selection	9797017
32316506	32316529	13	+	27869803	PATU8988S	viability after 31 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	0.2760950527824976	[287]	[36,268,NaN]	3	hSpCas9	negative selection	9879461
32326587	32326610	13	-	27869803	PATU8988S	viability after 31 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.084185369250499	[476]	[39,152,NaN]	-8	hSpCas9	negative selection	9879462
32333077	32333100	13	+	27869803	PATU8988S	viability after 31 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	1.3257192450702735	[244]	[210,287,NaN]	9	hSpCas9	negative selection	9879463
32339876	32339899	13	-	27869803	PATU8988S	viability after 31 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.4079626876480392	[671]	[175,234,NaN]	-4	hSpCas9	negative selection	9879464
32356493	32356516	13	+	27869803	PATU8988S	viability after 31 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	0.1020913683917475	[465]	[198,199,NaN]	1	hSpCas9	negative selection	9879465
32357889	32357912	13	+	27869803	PATU8988S	viability after 31 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-0.011898890433079824	[527]	[243,163,NaN]	0	hSpCas9	negative selection	9879466
32316506	32316529	13	+	27869803	HPAFII	viability after 35 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-4.446998456644628	[179]	[6,0,NaN]	-9	hSpCas9	negative selection	9961910
32326587	32326610	13	-	27869803	HPAFII	viability after 35 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.2885063509330362	[200]	[0,175,NaN]	-2	hSpCas9	negative selection	9961911
32333077	32333100	13	+	27869803	HPAFII	viability after 35 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.9737194197469765	[163]	[28,313,NaN]	6	hSpCas9	negative selection	9961912
32339876	32339899	13	-	27869803	HPAFII	viability after 35 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	0.03812398840609221	[348]	[60,316,NaN]	0	hSpCas9	negative selection	9961913
32356493	32356516	13	+	27869803	HPAFII	viability after 35 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.838593204365198	[189]	[97,3,NaN]	-5	hSpCas9	negative selection	9961914
32357889	32357912	13	+	27869803	HPAFII	viability after 35 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-1.7750078427763003	[289]	[72,8,NaN]	-7	hSpCas9	negative selection	9961915
32316506	32316529	13	+	27869803	HPAFII	viability after 31 days	AAGACACGCTGCAACAAAGCAGG	BRCA2	ENSG00000139618	-4.612839231098705	[179]	[6,0,NaN]	-9	hSpCas9	negative selection	10044359
32326587	32326610	13	-	27869803	HPAFII	viability after 31 days	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.5581389704250378	[200]	[0,158,NaN]	-4	hSpCas9	negative selection	10044360
32333077	32333100	13	+	27869803	HPAFII	viability after 31 days	TGAAGCCTCTGAAAGTGGACTGG	BRCA2	ENSG00000139618	0.9750386776050977	[163]	[33,340,NaN]	7	hSpCas9	negative selection	10044361
32339876	32339899	13	-	27869803	HPAFII	viability after 31 days	CTGGCTATCCTAAATGCAGGTGG	BRCA2	ENSG00000139618	-0.5531704845993439	[348]	[54,218,NaN]	-4	hSpCas9	negative selection	10044362
32356493	32356516	13	+	27869803	HPAFII	viability after 31 days	CAACGCGTCTTTCCACAGCCAGG	BRCA2	ENSG00000139618	-0.5919718263863922	[189]	[131,3,NaN]	-4	hSpCas9	negative selection	10044363
32357889	32357912	13	+	27869803	HPAFII	viability after 31 days	CCCTCCAATGATGGAAAGGCTGG	BRCA2	ENSG00000139618	-3.3191057630599414	[289]	[11,20,NaN]	-9	hSpCas9	negative selection	10044364
32326587	32326610	13	-	28162770	P31FUJ	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.21769531202417025	[94]	[95]	-2	hSpCas9	negative selection	10119010
32337317	32337340	13	+	28162770	P31FUJ	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.6587280198359586	[132]	[98]	-5	hSpCas9	negative selection	10119011
32371015	32371038	13	+	28162770	P31FUJ	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-1.1396928000228972	[149]	[79]	-7	hSpCas9	negative selection	10119012
32319127	32319150	13	-	28162770	P31FUJ	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.29028769907513874	[255]	[245]	-3	hSpCas9	negative selection	10119013
32332849	32332872	13	+	28162770	P31FUJ	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.020954387831404464	[103]	[123]	0	hSpCas9	negative selection	10119014
32339047	32339070	13	+	28162770	P31FUJ	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-0.10447810743883945	[42]	[46]	-1	hSpCas9	negative selection	10119015
32379397	32379420	13	+	28162770	P31FUJ	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.3935555599584404	[587]	[525]	-4	hSpCas9	negative selection	10119016
32380088	32380111	13	-	28162770	P31FUJ	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.3682799616700546	[88]	[134]	4	hSpCas9	negative selection	10119017
32326525	32326548	13	+	28162770	P31FUJ	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.06375662698033291	[546]	[614]	0	hSpCas9	negative selection	10119018
32332939	32332962	13	+	28162770	P31FUJ	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-0.7039827817307562	[261]	[188]	-5	hSpCas9	negative selection	10119019
32326587	32326610	13	-	28162770	TF1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10288376
32337317	32337340	13	+	28162770	TF1	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10288377
32371015	32371038	13	+	28162770	TF1	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10288378
32319127	32319150	13	-	28162770	TF1	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10288379
32332849	32332872	13	+	28162770	TF1	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10288380
32339047	32339070	13	+	28162770	TF1	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10288381
32379397	32379420	13	+	28162770	TF1	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	NaN	[NaN]	[320]	1	hSpCas9	negative selection	10288382
32380088	32380111	13	-	28162770	TF1	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10288383
32326525	32326548	13	+	28162770	TF1	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10288384
32332939	32332962	13	+	28162770	TF1	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10288385
32326587	32326610	13	-	28162770	SKM1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.5224414161630975	[25]	[15]	-7	hSpCas9	negative selection	10457742
32337317	32337340	13	+	28162770	SKM1	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.06992921146559095	[18]	[31]	0	hSpCas9	negative selection	10457743
32371015	32371038	13	+	28162770	SKM1	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.179553702640089	[40]	[15]	-8	hSpCas9	negative selection	10457744
32319127	32319150	13	-	28162770	SKM1	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	0.3248396903072657	[69]	[154]	3	hSpCas9	negative selection	10457745
32332849	32332872	13	+	28162770	SKM1	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.0710830980614825	[20]	[38]	0	hSpCas9	negative selection	10457746
32339047	32339070	13	+	28162770	SKM1	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	1.307281318922961	[15]	[69]	9	hSpCas9	negative selection	10457747
32379397	32379420	13	+	28162770	SKM1	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.5218779734529916	[159]	[196]	-4	hSpCas9	negative selection	10457748
32380088	32380111	13	-	28162770	SKM1	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-1.500073603134643	[23]	[14]	-7	hSpCas9	negative selection	10457749
32326525	32326548	13	+	28162770	SKM1	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.5314865557661047	[129]	[158]	-4	hSpCas9	negative selection	10457750
32332939	32332962	13	+	28162770	SKM1	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.3337929745854188	[56]	[126]	3	hSpCas9	negative selection	10457751
32326587	32326610	13	-	28162770	SKM1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.5224414161630975	[25]	[15]	-7	hSpCas9	negative selection	10627108
32337317	32337340	13	+	28162770	SKM1	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.06992921146559095	[18]	[31]	0	hSpCas9	negative selection	10627109
32371015	32371038	13	+	28162770	SKM1	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.179553702640089	[40]	[15]	-8	hSpCas9	negative selection	10627110
32319127	32319150	13	-	28162770	SKM1	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	0.3248396903072657	[69]	[154]	3	hSpCas9	negative selection	10627111
32332849	32332872	13	+	28162770	SKM1	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.0710830980614825	[20]	[38]	0	hSpCas9	negative selection	10627112
32339047	32339070	13	+	28162770	SKM1	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	1.307281318922961	[15]	[69]	9	hSpCas9	negative selection	10627113
32379397	32379420	13	+	28162770	SKM1	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.5218779734529916	[159]	[196]	-4	hSpCas9	negative selection	10627114
32380088	32380111	13	-	28162770	SKM1	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-1.500073603134643	[23]	[14]	-7	hSpCas9	negative selection	10627115
32326525	32326548	13	+	28162770	SKM1	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.5314865557661047	[129]	[158]	-4	hSpCas9	negative selection	10627116
32332939	32332962	13	+	28162770	SKM1	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.3337929745854188	[56]	[126]	3	hSpCas9	negative selection	10627117
32326587	32326610	13	-	28162770	PL21	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.3249514302544374	[117]	[40]	-2	hSpCas9	negative selection	10796474
32337317	32337340	13	+	28162770	PL21	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	0.797380444988913	[77]	[58]	6	hSpCas9	negative selection	10796475
32371015	32371038	13	+	28162770	PL21	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-1.0500870150438535	[156]	[32]	-6	hSpCas9	negative selection	10796476
32319127	32319150	13	-	28162770	PL21	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.5003001036517719	[298]	[91]	-4	hSpCas9	negative selection	10796477
32332849	32332872	13	+	28162770	PL21	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.05996195644105984	[107]	[48]	0	hSpCas9	negative selection	10796478
32339047	32339070	13	+	28162770	PL21	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.6728926116244511	[48]	[33]	6	hSpCas9	negative selection	10796479
32379397	32379420	13	+	28162770	PL21	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	0.1214562647968418	[470]	[222]	1	hSpCas9	negative selection	10796480
32380088	32380111	13	-	28162770	PL21	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.9977997631225886	[77]	[16]	-6	hSpCas9	negative selection	10796481
32326525	32326548	13	+	28162770	PL21	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	0.5168391945748714	[386]	[240]	4	hSpCas9	negative selection	10796482
32332939	32332962	13	+	28162770	PL21	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.32072975530290854	[194]	[105]	3	hSpCas9	negative selection	10796483
32326587	32326610	13	-	28162770	P31FUJ	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.21769531202417025	[94]	[95]	-2	hSpCas9	negative selection	10965840
32337317	32337340	13	+	28162770	P31FUJ	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.6587280198359586	[132]	[98]	-5	hSpCas9	negative selection	10965841
32371015	32371038	13	+	28162770	P31FUJ	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-1.1396928000228972	[149]	[79]	-7	hSpCas9	negative selection	10965842
32319127	32319150	13	-	28162770	P31FUJ	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.29028769907513874	[255]	[245]	-3	hSpCas9	negative selection	10965843
32332849	32332872	13	+	28162770	P31FUJ	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.020954387831404464	[103]	[123]	0	hSpCas9	negative selection	10965844
32339047	32339070	13	+	28162770	P31FUJ	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-0.10447810743883945	[42]	[46]	-1	hSpCas9	negative selection	10965845
32379397	32379420	13	+	28162770	P31FUJ	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.3935555599584404	[587]	[525]	-4	hSpCas9	negative selection	10965846
32380088	32380111	13	-	28162770	P31FUJ	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.3682799616700546	[88]	[134]	4	hSpCas9	negative selection	10965847
32326525	32326548	13	+	28162770	P31FUJ	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.06375662698033291	[546]	[614]	0	hSpCas9	negative selection	10965848
32332939	32332962	13	+	28162770	P31FUJ	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-0.7039827817307562	[261]	[188]	-5	hSpCas9	negative selection	10965849
32326587	32326610	13	-	28162770	OCIAML5	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.4159674560573234	[67]	[45]	-7	hSpCas9	negative selection	11135206
32337317	32337340	13	+	28162770	OCIAML5	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-1.1788768871311055	[73]	[58]	-6	hSpCas9	negative selection	11135207
32371015	32371038	13	+	28162770	OCIAML5	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.4139454584721123	[123]	[41]	-8	hSpCas9	negative selection	11135208
32319127	32319150	13	-	28162770	OCIAML5	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.5160173677319818	[121]	[153]	-4	hSpCas9	negative selection	11135209
32332849	32332872	13	+	28162770	OCIAML5	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.11878708347648681	[24]	[48]	1	hSpCas9	negative selection	11135210
32339047	32339070	13	+	28162770	OCIAML5	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-3.001813690368679	[70]	[15]	-8	hSpCas9	negative selection	11135211
32379397	32379420	13	+	28162770	OCIAML5	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-1.1480928023086023	[344]	[280]	-6	hSpCas9	negative selection	11135212
32380088	32380111	13	-	28162770	OCIAML5	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.6780371710889482	[116]	[131]	-4	hSpCas9	negative selection	11135213
32326525	32326548	13	+	28162770	OCIAML5	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.6433719992571094	[256]	[296]	-4	hSpCas9	negative selection	11135214
32332939	32332962	13	+	28162770	OCIAML5	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.07393284769222613	[79]	[151]	0	hSpCas9	negative selection	11135215
32326587	32326610	13	-	28162770	EOL1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.9674695475564539	[192]	[25]	-8	hSpCas9	negative selection	11304572
32337317	32337340	13	+	28162770	EOL1	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	0.9478175508933817	[122]	[124]	7	hSpCas9	negative selection	11304573
32371015	32371038	13	+	28162770	EOL1	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-3.0296485388163408	[340]	[21]	-9	hSpCas9	negative selection	11304574
32319127	32319150	13	-	28162770	EOL1	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.55163838323329	[497]	[178]	-4	hSpCas9	negative selection	11304575
32332849	32332872	13	+	28162770	EOL1	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-2.053647858111117	[196]	[24]	-8	hSpCas9	negative selection	11304576
32339047	32339070	13	+	28162770	EOL1	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-0.8024337340230496	[95]	[28]	-5	hSpCas9	negative selection	11304577
32379397	32379420	13	+	28162770	EOL1	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.17769042236020338	[686]	[319]	-1	hSpCas9	negative selection	11304578
32380088	32380111	13	-	28162770	EOL1	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.08501244376378048	[101]	[56]	0	hSpCas9	negative selection	11304579
32326525	32326548	13	+	28162770	EOL1	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-1.640709319803063	[508]	[85]	-7	hSpCas9	negative selection	11304580
32332939	32332962	13	+	28162770	EOL1	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-1.119846347787919	[263]	[63]	-6	hSpCas9	negative selection	11304581
32326587	32326610	13	-	28162770	MOLM13	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.0360015085292595	[172]	[60]	-5	hSpCas9	negative selection	11473938
32337317	32337340	13	+	28162770	MOLM13	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-2.1721144827345396	[186]	[29]	-7	hSpCas9	negative selection	11473939
32371015	32371038	13	+	28162770	MOLM13	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-3.122786770370971	[252]	[20]	-8	hSpCas9	negative selection	11473940
32319127	32319150	13	-	28162770	MOLM13	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	0.017469004202250393	[398]	[291]	0	hSpCas9	negative selection	11473941
32332849	32332872	13	+	28162770	MOLM13	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-0.5962409558751369	[137]	[65]	-3	hSpCas9	negative selection	11473942
32339047	32339070	13	+	28162770	MOLM13	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.10312508874695858	[93]	[72]	0	hSpCas9	negative selection	11473943
32379397	32379420	13	+	28162770	MOLM13	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.15534313610429484	[572]	[371]	-1	hSpCas9	negative selection	11473944
32380088	32380111	13	-	28162770	MOLM13	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.8297911670961065	[235]	[95]	-4	hSpCas9	negative selection	11473945
32326525	32326548	13	+	28162770	MOLM13	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.7179139998674922	[570]	[250]	-4	hSpCas9	negative selection	11473946
32332939	32332962	13	+	28162770	MOLM13	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.8757670892505565	[201]	[267]	6	hSpCas9	negative selection	11473947
32326587	32326610	13	-	28162770	HEL	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.4687694832166334	[120]	[27]	-7	hSpCas9	negative selection	11643304
32337317	32337340	13	+	28162770	HEL	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.7378651702146128	[137]	[52]	-5	hSpCas9	negative selection	11643305
32371015	32371038	13	+	28162770	HEL	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.810433796165258	[229]	[20]	-8	hSpCas9	negative selection	11643306
32319127	32319150	13	-	28162770	HEL	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.3742342466033565	[341]	[168]	-3	hSpCas9	negative selection	11643307
32332849	32332872	13	+	28162770	HEL	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-0.03325874487442215	[138]	[86]	0	hSpCas9	negative selection	11643308
32339047	32339070	13	+	28162770	HEL	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-0.6951308067560269	[90]	[35]	-4	hSpCas9	negative selection	11643309
32379397	32379420	13	+	28162770	HEL	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.5167393820068397	[515]	[230]	-3	hSpCas9	negative selection	11643310
32380088	32380111	13	-	28162770	HEL	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-0.12082097217756238	[145]	[85]	-1	hSpCas9	negative selection	11643311
32326525	32326548	13	+	28162770	HEL	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.31058570662702367	[516]	[266]	-2	hSpCas9	negative selection	11643312
32332939	32332962	13	+	28162770	HEL	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-0.9004034930261722	[203]	[69]	-5	hSpCas9	negative selection	11643313
32326587	32326610	13	-	28162770	MV411	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	0.4049788277692553	[77]	[86]	3	hSpCas9	negative selection	11812670
32337317	32337340	13	+	28162770	MV411	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	0.9744190563763594	[57]	[95]	8	hSpCas9	negative selection	11812671
32371015	32371038	13	+	28162770	MV411	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-2.5025841962088773	[147]	[21]	-8	hSpCas9	negative selection	11812672
32319127	32319150	13	-	28162770	MV411	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.7731727288925108	[281]	[138]	-5	hSpCas9	negative selection	11812673
32332849	32332872	13	+	28162770	MV411	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-0.38779815641960447	[72]	[46]	-3	hSpCas9	negative selection	11812674
32339047	32339070	13	+	28162770	MV411	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-2.074490544104587	[59]	[11]	-8	hSpCas9	negative selection	11812675
32379397	32379420	13	+	28162770	MV411	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	0.20254101280845227	[358]	[347]	1	hSpCas9	negative selection	11812676
32380088	32380111	13	-	28162770	MV411	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.10725989273451475	[53]	[48]	0	hSpCas9	negative selection	11812677
32326525	32326548	13	+	28162770	MV411	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-1.054885986165076	[401]	[162]	-6	hSpCas9	negative selection	11812678
32332939	32332962	13	+	28162770	MV411	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.18330721336305966	[160]	[153]	1	hSpCas9	negative selection	11812679
32326587	32326610	13	-	28162770	MONOMAC1	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.49659712891846164	[47]	[38]	-4	hSpCas9	negative selection	11982036
32337317	32337340	13	+	28162770	MONOMAC1	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	0.9652345818393231	[41]	[93]	8	hSpCas9	negative selection	11982037
32371015	32371038	13	+	28162770	MONOMAC1	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-1.0450337536145038	[98]	[54]	-7	hSpCas9	negative selection	11982038
32319127	32319150	13	-	28162770	MONOMAC1	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.14836300032386407	[203]	[210]	-1	hSpCas9	negative selection	11982039
32332849	32332872	13	+	28162770	MONOMAC1	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	0.011549774751863806	[44]	[51]	0	hSpCas9	negative selection	11982040
32339047	32339070	13	+	28162770	MONOMAC1	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.27008916336774424	[33]	[46]	2	hSpCas9	negative selection	11982041
32379397	32379420	13	+	28162770	MONOMAC1	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.20788422929654615	[266]	[264]	-2	hSpCas9	negative selection	11982042
32380088	32380111	13	-	28162770	MONOMAC1	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-1.6376094384455353	[75]	[27]	-8	hSpCas9	negative selection	11982043
32326525	32326548	13	+	28162770	MONOMAC1	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.6387422968004778	[272]	[200]	-5	hSpCas9	negative selection	11982044
32332939	32332962	13	+	28162770	MONOMAC1	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.201047518938093	[106]	[140]	2	hSpCas9	negative selection	11982045
32326587	32326610	13	-	28162770	OCIAML2	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-0.5879867758803199	[15]	[58]	-4	hSpCas9	negative selection	12151402
32337317	32337340	13	+	28162770	OCIAML2	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	-0.20384328454725975	[15]	[76]	-2	hSpCas9	negative selection	12151403
32371015	32371038	13	+	28162770	OCIAML2	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-3.979643472730019	[36]	[12]	-9	hSpCas9	negative selection	12151404
32319127	32319150	13	-	28162770	OCIAML2	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-1.3208827057374792	[63]	[141]	-7	hSpCas9	negative selection	12151405
32332849	32332872	13	+	28162770	OCIAML2	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-0.2779847472997653	[20]	[95]	-2	hSpCas9	negative selection	12151406
32339047	32339070	13	+	28162770	OCIAML2	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	-0.5879867758803199	[15]	[58]	-4	hSpCas9	negative selection	12151407
32379397	32379420	13	+	28162770	OCIAML2	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.2089622551722734	[87]	[421]	-2	hSpCas9	negative selection	12151408
32380088	32380111	13	-	28162770	OCIAML2	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	0.04033209403521831	[9]	[56]	0	hSpCas9	negative selection	12151409
32326525	32326548	13	+	28162770	OCIAML2	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.8185531286624679	[83]	[263]	-5	hSpCas9	negative selection	12151410
32332939	32332962	13	+	28162770	OCIAML2	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	-0.9490927046626386	[30]	[88]	-6	hSpCas9	negative selection	12151411
32326587	32326610	13	-	28162770	OCIAML3	viability	GAGCACAGTAGAACTAAGGGTGG	BRCA2	ENSG00000139618	-1.4189209337660718	[30]	[34]	-7	hSpCas9	negative selection	12320768
32337317	32337340	13	+	28162770	OCIAML3	viability	GATTACATGAACAAATGGGCAGG	BRCA2	ENSG00000139618	1.005030045608716	[33]	[205]	8	hSpCas9	negative selection	12320769
32371015	32371038	13	+	28162770	OCIAML3	viability	GGAAGCAGCAAAATATGTGGAGG	BRCA2	ENSG00000139618	-4.401362562381767	[48]	[6]	-9	hSpCas9	negative selection	12320770
32319127	32319150	13	-	28162770	OCIAML3	viability	GCAGGTTCAGAATTATAGGGTGG	BRCA2	ENSG00000139618	-0.6133729651910941	[74]	[147]	-5	hSpCas9	negative selection	12320771
32332849	32332872	13	+	28162770	OCIAML3	viability	GCCATTAAATGAGGAAACAGTGG	BRCA2	ENSG00000139618	-1.1934697107404344	[24]	[32]	-7	hSpCas9	negative selection	12320772
32339047	32339070	13	+	28162770	OCIAML3	viability	AAAGACCCTAAAGTACAGAGAGG	BRCA2	ENSG00000139618	0.17152710603881394	[14]	[50]	1	hSpCas9	negative selection	12320773
32379397	32379420	13	+	28162770	OCIAML3	viability	GTTGGAAATTAGGAAGGCCATGG	BRCA2	ENSG00000139618	-0.3950266055977676	[141]	[325]	-3	hSpCas9	negative selection	12320774
32380088	32380111	13	-	28162770	OCIAML3	viability	AGGTCCACCTCAGAACAAGATGG	BRCA2	ENSG00000139618	-1.0345802317101447	[18]	[27]	-6	hSpCas9	negative selection	12320775
32326525	32326548	13	+	28162770	OCIAML3	viability	TGAAAGTCTAGGAGCTGAGGTGG	BRCA2	ENSG00000139618	-0.9691524124794946	[106]	[164]	-6	hSpCas9	negative selection	12320776
32332939	32332962	13	+	28162770	OCIAML3	viability	AATATCTGGAACTTCTCCAGTGG	BRCA2	ENSG00000139618	0.017427071758184143	[35]	[109]	0	hSpCas9	negative selection	12320777