Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 54014
• Symbol: BRWD1
• Description: bromodomain and WD repeat domain containing 1

DataSource: http://genomecrispr.dkfz.de/#!/results/BRWD1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
39312876	39312899	21	-	26472758	Jiyoye	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.8313150878919696	[236]	[317]	6	hSpCas9	negative selection	16291
39202426	39202449	21	-	26472758	Jiyoye	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-0.8132146869194266	[239]	[102]	-5	hSpCas9	negative selection	16292
39312840	39312863	21	-	26472758	Jiyoye	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.2687286115367291	[152]	[138]	2	hSpCas9	negative selection	16293
39313436	39313459	21	+	26472758	Jiyoye	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.3395894854499386	[436]	[416]	2	hSpCas9	negative selection	16294
39313071	39313094	21	-	26472758	Jiyoye	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.5341806582411934	[162]	[177]	4	hSpCas9	negative selection	16295
39313449	39313472	21	+	26472758	Jiyoye	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	1.2733196347710827	[78]	[143]	7	hSpCas9	negative selection	16296
39313239	39313262	21	+	26472758	Jiyoye	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.8222128807847173	[92]	[123]	6	hSpCas9	negative selection	16297
39298513	39298536	21	-	26472758	Jiyoye	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.32471322131390057	[377]	[356]	2	hSpCas9	negative selection	16298
39313089	39313112	21	-	26472758	Jiyoye	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	2.0196186186491367	[51]	[158]	8	hSpCas9	negative selection	16299
39258486	39258509	21	-	26472758	Jiyoye	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.7686744538935443	[182]	[80]	-5	hSpCas9	negative selection	16300
39312876	39312899	21	-	26472758	KBM7	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.3248577224034015	[1147,744]	[566,530]	3	hSpCas9	negative selection	207409
39202426	39202449	21	-	26472758	KBM7	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.4228317985933914	[538,546]	[302,380]	4	hSpCas9	negative selection	207410
39312840	39312863	21	-	26472758	KBM7	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.7360213822795436	[488,463]	[600,170]	7	hSpCas9	negative selection	207411
39313436	39313459	21	+	26472758	KBM7	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.44269102879713995	[1931,1732]	[1259,1089]	5	hSpCas9	negative selection	207412
39313071	39313094	21	-	26472758	KBM7	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.1646906311220998	[973,575]	[489,318]	1	hSpCas9	negative selection	207413
39313449	39313472	21	+	26472758	KBM7	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.3445711588491513	[702,566]	[455,305]	3	hSpCas9	negative selection	207414
39313239	39313262	21	+	26472758	KBM7	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.4228279735044744	[470,309]	[229,252]	4	hSpCas9	negative selection	207415
39298513	39298536	21	-	26472758	KBM7	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.6953461164004617	[1873,1886]	[1406,1467]	7	hSpCas9	negative selection	207416
39313089	39313112	21	-	26472758	KBM7	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.32128291632761785	[448,547]	[125,247]	-3	hSpCas9	negative selection	207417
39258486	39258509	21	-	26472758	KBM7	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.3551100700928572	[400,273]	[116,126]	-3	hSpCas9	negative selection	207418
39312876	39312899	21	-	26472758	Raji	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	-0.4497610212077944	[564]	[95]	-4	hSpCas9	negative selection	398527
39202426	39202449	21	-	26472758	Raji	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.3488408626689393	[246]	[72]	3	hSpCas9	negative selection	398528
39312840	39312863	21	-	26472758	Raji	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.5458800074764322	[182]	[61]	5	hSpCas9	negative selection	398529
39313436	39313459	21	+	26472758	Raji	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.3242761595626724	[825]	[239]	3	hSpCas9	negative selection	398530
39313071	39313094	21	-	26472758	Raji	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.38653760657067016	[266]	[80]	3	hSpCas9	negative selection	398531
39313449	39313472	21	+	26472758	Raji	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.602763142970047	[226]	[79]	6	hSpCas9	negative selection	398532
39313239	39313262	21	+	26472758	Raji	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.8849911140371514	[188]	[80]	7	hSpCas9	negative selection	398533
39298513	39298536	21	-	26472758	Raji	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.22747073395803308	[1008]	[199]	-2	hSpCas9	negative selection	398534
39313089	39313112	21	-	26472758	Raji	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.19217674648530825	[255]	[51]	-2	hSpCas9	negative selection	398535
39258486	39258509	21	-	26472758	Raji	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.9885408846249358	[341]	[39]	-6	hSpCas9	negative selection	398536
39312876	39312899	21	-	26472758	K562	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.37119331244878473	[772]	[843]	3	hSpCas9	negative selection	589645
39202426	39202449	21	-	26472758	K562	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.21825206568498046	[611]	[600]	1	hSpCas9	negative selection	589646
39312840	39312863	21	-	26472758	K562	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.32054979688241764	[405]	[427]	2	hSpCas9	negative selection	589647
39313436	39313459	21	+	26472758	K562	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.7097837805037157	[1499]	[2070]	6	hSpCas9	negative selection	589648
39313071	39313094	21	-	26472758	K562	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	-0.3760702066838504	[554]	[360]	-2	hSpCas9	negative selection	589649
39313449	39313472	21	+	26472758	K562	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.829381228387603	[613]	[920]	7	hSpCas9	negative selection	589650
39313239	39313262	21	+	26472758	K562	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.07088642502718043	[325]	[261]	0	hSpCas9	negative selection	589651
39298513	39298536	21	-	26472758	K562	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.5169807452328294	[1634]	[1974]	4	hSpCas9	negative selection	589652
39313089	39313112	21	-	26472758	K562	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.5844941692640684	[315]	[799]	9	hSpCas9	negative selection	589653
39258486	39258509	21	-	26472758	K562	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.5724729253506506	[281]	[353]	4	hSpCas9	negative selection	589654
39255776	39255799	21	+	26627737	DLD1	viability	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.02453261175700605	[754]	[110,243,326]	0	hSpCas9	negative selection	816198
39270414	39270437	21	-	26627737	DLD1	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.12255189527806781	[321]	[114,135,82]	1	hSpCas9	negative selection	816199
39278757	39278780	21	+	26627737	DLD1	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.1633211519198543	[278]	[67,139,34]	-2	hSpCas9	negative selection	816200
39280186	39280209	21	+	26627737	DLD1	viability	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.013013160708219396	[591]	[181,229,154]	0	hSpCas9	negative selection	816201
39313442	39313465	21	+	26627737	DLD1	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.990186432176837	[669]	[443,387,414]	8	hSpCas9	negative selection	816202
39255776	39255799	21	+	26627737	GBM cells	viability after 5 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.08628912318623383	[484]	[201,287]	-1	hSpCas9	negative selection	898513
39270414	39270437	21	-	26627737	GBM cells	viability after 5 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.4267566216874934	[192]	[60,92]	-6	hSpCas9	negative selection	898514
39278757	39278780	21	+	26627737	GBM cells	viability after 5 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.03511825848399641	[100]	[59,50]	0	hSpCas9	negative selection	898515
39280186	39280209	21	+	26627737	GBM cells	viability after 5 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.23856956232239196	[274]	[192,154]	4	hSpCas9	negative selection	898516
39313442	39313465	21	+	26627737	GBM cells	viability after 5 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.019447656089957188	[291]	[124,183]	0	hSpCas9	negative selection	898517
39255776	39255799	21	+	26627737	GBM cells	viability after 13 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.14009811568615305	[484]	[332,254]	1	hSpCas9	negative selection	980828
39270414	39270437	21	-	26627737	GBM cells	viability after 13 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.24887446640347688	[192]	[59,110]	-3	hSpCas9	negative selection	980829
39278757	39278780	21	+	26627737	GBM cells	viability after 13 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.19374367735901665	[100]	[108,24]	2	hSpCas9	negative selection	980830
39280186	39280209	21	+	26627737	GBM cells	viability after 13 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.41148983027030006	[274]	[214,184]	5	hSpCas9	negative selection	980831
39313442	39313465	21	+	26627737	GBM cells	viability after 13 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.11289217278671286	[291]	[199,102]	-1	hSpCas9	negative selection	980832
39255776	39255799	21	+	26627737	GBM cells	viability after 21 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.15571828453080683	[484]	[292,293]	1	hSpCas9	negative selection	1063143
39270414	39270437	21	-	26627737	GBM cells	viability after 21 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.4157663302811777	[192]	[87,69]	-4	hSpCas9	negative selection	1063144
39278757	39278780	21	+	26627737	GBM cells	viability after 21 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-2.1418369584894172	[100]	[13,10]	-9	hSpCas9	negative selection	1063145
39280186	39280209	21	+	26627737	GBM cells	viability after 21 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.5314618821005214	[274]	[228,203]	5	hSpCas9	negative selection	1063146
39313442	39313465	21	+	26627737	GBM cells	viability after 21 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.6409426080383469	[291]	[107,95]	-5	hSpCas9	negative selection	1063147
39255776	39255799	21	+	26627737	RPE1	viability after 9 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.02994288043269666	[1757]	[511,573]	0	hSpCas9	negative selection	1145458
39270414	39270437	21	-	26627737	RPE1	viability after 9 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.26121257514350416	[299]	[42,123]	-2	hSpCas9	negative selection	1145459
39278757	39278780	21	+	26627737	RPE1	viability after 9 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.1066867603108772	[105]	[53,93]	6	hSpCas9	negative selection	1145460
39280186	39280209	21	+	26627737	RPE1	viability after 9 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.4416776318461709	[715]	[154,177]	-3	hSpCas9	negative selection	1145461
39313442	39313465	21	+	26627737	RPE1	viability after 9 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.395258943732862	[1606]	[137,259]	-7	hSpCas9	negative selection	1145462
39255776	39255799	21	+	26627737	RPE1	viability after 12 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.4019263842736174	[1757]	[676,567]	2	hSpCas9	negative selection	1227773
39270414	39270437	21	-	26627737	RPE1	viability after 12 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.4244433418055311	[299]	[78,39]	-3	hSpCas9	negative selection	1227774
39278757	39278780	21	+	26627737	RPE1	viability after 12 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.177179740337193	[105]	[77,49]	7	hSpCas9	negative selection	1227775
39280186	39280209	21	+	26627737	RPE1	viability after 12 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.06997874409443833	[715]	[174,191]	0	hSpCas9	negative selection	1227776
39313442	39313465	21	+	26627737	RPE1	viability after 12 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-2.759851020702782	[1606]	[37,90]	-9	hSpCas9	negative selection	1227777
39255776	39255799	21	+	26627737	RPE1	viability after 15 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.3627586096668738	[1757]	[584,691]	2	hSpCas9	negative selection	1310088
39270414	39270437	21	-	26627737	RPE1	viability after 15 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.002321119513715386	[299]	[84,84]	0	hSpCas9	negative selection	1310089
39278757	39278780	21	+	26627737	RPE1	viability after 15 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.5543629234208409	[105]	[24,15]	-4	hSpCas9	negative selection	1310090
39280186	39280209	21	+	26627737	RPE1	viability after 15 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.45325325026039287	[715]	[235,62]	-3	hSpCas9	negative selection	1310091
39313442	39313465	21	+	26627737	RPE1	viability after 15 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-2.5565832092109995	[1606]	[33,118]	-8	hSpCas9	negative selection	1310092
39255776	39255799	21	+	26627737	RPE1	viability after 18 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.4023359661059145	[1757]	[656,594]	2	hSpCas9	negative selection	1392403
39270414	39270437	21	-	26627737	RPE1	viability after 18 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.7845615787175009	[299]	[46,46]	-5	hSpCas9	negative selection	1392404
39278757	39278780	21	+	26627737	RPE1	viability after 18 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.19932736359776637	[105]	[36,11]	-1	hSpCas9	negative selection	1392405
39280186	39280209	21	+	26627737	RPE1	viability after 18 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.7264149731704873	[715]	[95,138]	-4	hSpCas9	negative selection	1392406
39313442	39313465	21	+	26627737	RPE1	viability after 18 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.7563254074443022	[1606]	[109,147]	-8	hSpCas9	negative selection	1392407
39255776	39255799	21	+	26627737	HeLa	viability after 8 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-1.5464996919071237	[1159]	[361,83,117]	-9	hSpCas9	negative selection	1474718
39270414	39270437	21	-	26627737	HeLa	viability after 8 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.19561890389459835	[260]	[189,136,79]	2	hSpCas9	negative selection	1474719
39278757	39278780	21	+	26627737	HeLa	viability after 8 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.126549644250505	[76]	[121,105,6]	8	hSpCas9	negative selection	1474720
39280186	39280209	21	+	26627737	HeLa	viability after 8 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.32735883516200925	[345]	[202,150,213]	3	hSpCas9	negative selection	1474721
39313442	39313465	21	+	26627737	HeLa	viability after 8 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.492142214735235	[1003]	[214,33,224]	-9	hSpCas9	negative selection	1474722
39255776	39255799	21	+	26627737	HeLa	viability after 12 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-1.0321444312984664	[1159]	[244,97,374]	-7	hSpCas9	negative selection	1557033
39270414	39270437	21	-	26627737	HeLa	viability after 12 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-1.0613763688097926	[260]	[52,61,38]	-7	hSpCas9	negative selection	1557034
39278757	39278780	21	+	26627737	HeLa	viability after 12 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.014895936645544	[76]	[81,39,73]	7	hSpCas9	negative selection	1557035
39280186	39280209	21	+	26627737	HeLa	viability after 12 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.6206038933357019	[345]	[103,381,152]	5	hSpCas9	negative selection	1557036
39313442	39313465	21	+	26627737	HeLa	viability after 12 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.7688042270899818	[1003]	[111,149,99]	-9	hSpCas9	negative selection	1557037
39255776	39255799	21	+	26627737	HeLa	viability after 15 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-1.0848660171869384	[1159]	[138,149,392]	-7	hSpCas9	negative selection	1639348
39270414	39270437	21	-	26627737	HeLa	viability after 15 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-2.006447610662994	[260]	[31,23,22]	-9	hSpCas9	negative selection	1639349
39278757	39278780	21	+	26627737	HeLa	viability after 15 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.2554667853087615	[76]	[0,106,120]	8	hSpCas9	negative selection	1639350
39280186	39280209	21	+	26627737	HeLa	viability after 15 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.03832111378834738	[345]	[149,173,106]	0	hSpCas9	negative selection	1639351
39313442	39313465	21	+	26627737	HeLa	viability after 15 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.9287827773146107	[1003]	[198,306,131]	-7	hSpCas9	negative selection	1639352
39255776	39255799	21	+	26627737	HeLa	viability after 18 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-1.093646353633942	[1159]	[89,124,392]	-7	hSpCas9	negative selection	1721663
39270414	39270437	21	-	26627737	HeLa	viability after 18 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-2.005580030506405	[260]	[22,17,22]	-9	hSpCas9	negative selection	1721664
39278757	39278780	21	+	26627737	HeLa	viability after 18 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.2853817846517752	[76]	[0,91,120]	8	hSpCas9	negative selection	1721665
39280186	39280209	21	+	26627737	HeLa	viability after 18 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.08023217550031225	[345]	[100,153,106]	0	hSpCas9	negative selection	1721666
39313442	39313465	21	+	26627737	HeLa	viability after 18 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.8781610451712347	[1003]	[142,260,131]	-6	hSpCas9	negative selection	1721667
39255776	39255799	21	+	26627737	HCT116	viability after 6 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	1.0021727994377154	[742]	[329,180]	5	hSpCas9	negative selection	1803978
39270414	39270437	21	-	26627737	HCT116	viability after 6 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.4628886310626434	[583]	[219,74]	2	hSpCas9	negative selection	1803979
39278757	39278780	21	+	26627737	HCT116	viability after 6 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-1.016383125613788	[313]	[6,33]	-5	hSpCas9	negative selection	1803980
39280186	39280209	21	+	26627737	HCT116	viability after 6 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	1.5677118352065247	[506]	[214,247]	7	hSpCas9	negative selection	1803981
39313442	39313465	21	+	26627737	HCT116	viability after 6 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.3701189858524145	[1079]	[104,43]	-7	hSpCas9	negative selection	1803982
39255776	39255799	21	+	26627737	HCT116	viability after 8 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.5804378970127722	[803]	[268,211,405]	-6	hSpCas9	negative selection	1886293
39270414	39270437	21	-	26627737	HCT116	viability after 8 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.7402904718593023	[96]	[95,83,87]	7	hSpCas9	negative selection	1886294
39278757	39278780	21	+	26627737	HCT116	viability after 8 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.7782595139431625	[49]	[106,103,72]	9	hSpCas9	negative selection	1886295
39280186	39280209	21	+	26627737	HCT116	viability after 8 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.8507747055164838	[612]	[248,127,185]	-8	hSpCas9	negative selection	1886296
39313442	39313465	21	+	26627737	HCT116	viability after 8 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.34068458492225606	[371]	[152,133,197]	-4	hSpCas9	negative selection	1886297
39255776	39255799	21	+	26627737	HCT116	viability after 9 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.7633730879539894	[742]	[524,187]	5	hSpCas9	negative selection	1968608
39270414	39270437	21	-	26627737	HCT116	viability after 9 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.9159154217946938	[583]	[23,128]	-6	hSpCas9	negative selection	1968609
39278757	39278780	21	+	26627737	HCT116	viability after 9 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.09691550234773494	[313]	[45,103]	0	hSpCas9	negative selection	1968610
39280186	39280209	21	+	26627737	HCT116	viability after 9 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.03977106351863549	[506]	[232,64]	0	hSpCas9	negative selection	1968611
39313442	39313465	21	+	26627737	HCT116	viability after 9 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.3587957423648693	[1079]	[50,160]	-7	hSpCas9	negative selection	1968612
39255776	39255799	21	+	26627737	HCT116	viability after 12 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.5861122824311908	[803]	[226,274,346]	-6	hSpCas9	negative selection	2050923
39270414	39270437	21	-	26627737	HCT116	viability after 12 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	1.1617727507559383	[96]	[85,129,128]	8	hSpCas9	negative selection	2050924
39278757	39278780	21	+	26627737	HCT116	viability after 12 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.76156367137717	[49]	[93,53,117]	9	hSpCas9	negative selection	2050925
39280186	39280209	21	+	26627737	HCT116	viability after 12 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.9445425141399995	[612]	[217,137,140]	-7	hSpCas9	negative selection	2050926
39313442	39313465	21	+	26627737	HCT116	viability after 12 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.35123903262284606	[371]	[154,210,94]	-4	hSpCas9	negative selection	2050927
39255776	39255799	21	+	26627737	HCT116	viability after 15 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.7092491115635721	[803]	[377,125,353]	-6	hSpCas9	negative selection	2133238
39270414	39270437	21	-	26627737	HCT116	viability after 15 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.9722990000696835	[96]	[97,76,150]	7	hSpCas9	negative selection	2133239
39278757	39278780	21	+	26627737	HCT116	viability after 15 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.9097334036629068	[49]	[86,31,200]	9	hSpCas9	negative selection	2133240
39280186	39280209	21	+	26627737	HCT116	viability after 15 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-1.24910286635677	[612]	[220,67,163]	-8	hSpCas9	negative selection	2133241
39313442	39313465	21	+	26627737	HCT116	viability after 15 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.09949042470761338	[371]	[275,319,97]	1	hSpCas9	negative selection	2133242
39255776	39255799	21	+	26627737	HCT116	viability after 18 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.4621359581370258	[803]	[191,151,521]	-4	hSpCas9	negative selection	2215553
39270414	39270437	21	-	26627737	HCT116	viability after 18 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.43060642588300757	[96]	[53,37,100]	3	hSpCas9	negative selection	2215554
39278757	39278780	21	+	26627737	HCT116	viability after 18 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.7297526590061403	[49]	[76,25,143]	9	hSpCas9	negative selection	2215555
39280186	39280209	21	+	26627737	HCT116	viability after 18 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-1.505274636971789	[612]	[227,20,67]	-8	hSpCas9	negative selection	2215556
39313442	39313465	21	+	26627737	HCT116	viability after 18 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.27579297978542505	[371]	[101,275,54]	-3	hSpCas9	negative selection	2215557
39313239	39313262	21	+	24336569	HL60	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	1.2927121429247475	[140]	[730]	8	hSpCas9	negative selection	2250488
39313246	39313269	21	-	24336569	HL60	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.5975338952660855	[291]	[934]	5	hSpCas9	negative selection	2250489
39313253	39313276	21	-	24336569	HL60	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	-0.5918085600034674	[291]	[409]	-5	hSpCas9	negative selection	2250490
39313267	39313290	21	+	24336569	HL60	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.9301400822921191	[424]	[471]	-7	hSpCas9	negative selection	2250491
39313277	39313300	21	-	24336569	HL60	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.8163123907793138	[306]	[1143]	6	hSpCas9	negative selection	2250492
39313436	39313459	21	+	24336569	HL60	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-0.5111483758721416	[527]	[783]	-4	hSpCas9	negative selection	2250493
39313442	39313465	21	-	24336569	HL60	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	2.2059917770013264	[71]	[702]	9	hSpCas9	negative selection	2250494
39313449	39313472	21	+	24336569	HL60	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.4025090167309797	[921]	[2578]	3	hSpCas9	negative selection	2250495
39313460	39313483	21	+	24336569	HL60	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	-0.06719753155584796	[804]	[1625]	0	hSpCas9	negative selection	2250496
39313471	39313494	21	+	24336569	HL60	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.028558686698931468	[264]	[571]	0	hSpCas9	negative selection	2250497
39313239	39313262	21	+	24336569	KBM7	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.9113281103009581	[250]	[363]	-6	hSpCas9	negative selection	2317665
39313246	39313269	21	-	24336569	KBM7	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.15827067064609723	[159]	[486]	1	hSpCas9	negative selection	2317666
39313253	39313276	21	-	24336569	KBM7	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	0.11970841184908265	[218]	[648]	1	hSpCas9	negative selection	2317667
39313267	39313290	21	+	24336569	KBM7	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.3613054224068904	[356]	[757]	-3	hSpCas9	negative selection	2317668
39313277	39313300	21	-	24336569	KBM7	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.16135517688181666	[377]	[1152]	1	hSpCas9	negative selection	2317669
39313436	39313459	21	+	24336569	KBM7	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-1.4056069260735666	[270]	[278]	-7	hSpCas9	negative selection	2317670
39313442	39313465	21	-	24336569	KBM7	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.3532180094865591	[125]	[438]	3	hSpCas9	negative selection	2317671
39313449	39313472	21	+	24336569	KBM7	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	-0.4450265063384178	[846]	[1696]	-4	hSpCas9	negative selection	2317672
39313460	39313483	21	+	24336569	KBM7	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	-0.11193282041374009	[627]	[1584]	-1	hSpCas9	negative selection	2317673
39313471	39313494	21	+	24336569	KBM7	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.3561233310493884	[225]	[788]	3	hSpCas9	negative selection	2317674
39311205	39311228	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAATGCAGTGG	BRWD1	ENSG00000185658	-0.2783317302750946	[134,222]	[33,30]	-1	dCas9-VP64	positive selection	2393458
39306210	39306233	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCGCCACCACGTCTGG	BRWD1	ENSG00000185658	1.5618735705212097	[103,49]	[83,12]	6	dCas9-VP64	positive selection	2398383
39305050	39305073	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATTGCTTGAATCCAAG	BRWD1	ENSG00000185658	2.433140723417131	[10,9]	[10,13]	7	dCas9-VP64	positive selection	2414312
39275869	39275892	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAAAAATACAAAGTTAGCCGGG	BRWD1	ENSG00000185658	0.3906432334662431	[10,116]	[2,33]	1	dCas9-VP64	positive selection	2417228
39200949	39200972	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGAAAG	BRWD1	ENSG00000185658	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454919
39289820	39289843	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCATCTTGGCTAACACGG	BRWD1	ENSG00000185658	-0.8978621526762642	[150,655]	[5,91]	-5	dCas9-VP64	positive selection	2460970
39313883	39313906	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCTGCCCGGGCTTTGTGAGG	BRWD1	ENSG00000185658	5.730112420665052	[0,5]	[79,7]	9	dCas9-VP64	positive selection	2461680
39260380	39260403	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGGGAGGCTGAGGCAGGCAGG	BRWD1	ENSG00000185658	0.6597088728489087	[159,20]	[40,18]	3	dCas9-VP64	positive selection	2472693
39311205	39311228	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAATGCAGTGG	BRWD1	ENSG00000185658	4.153514066093628	[144,313]	[24,2552]	9	dCas9-VP64	positive selection	2488713
39306210	39306233	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCGCCACCACGTCTGG	BRWD1	ENSG00000185658	0.22222393386236713	[95,81]	[49,17]	1	dCas9-VP64	positive selection	2493638
39305050	39305073	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATTGCTTGAATCCAAG	BRWD1	ENSG00000185658	-0.8838793156856553	[97,17]	[18,1]	-8	dCas9-VP64	positive selection	2509567
39275869	39275892	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAAAAATACAAAGTTAGCCGGG	BRWD1	ENSG00000185658	-0.2979935386794893	[181,221]	[40,64]	-3	dCas9-VP64	positive selection	2512483
39200949	39200972	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGAAAG	BRWD1	ENSG00000185658	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550174
39289820	39289843	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCATCTTGGCTAACACGG	BRWD1	ENSG00000185658	2.463185390337416	[53,170]	[40,350]	9	dCas9-VP64	positive selection	2556225
39313883	39313906	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCTGCCCGGGCTTTGTGAGG	BRWD1	ENSG00000185658	-1.212362443381259	[258,39]	[28,12]	-9	dCas9-VP64	positive selection	2556935
39260380	39260403	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGGGAGGCTGAGGCAGGCAGG	BRWD1	ENSG00000185658	0.628589961662267	[19,33]	[6,18]	4	dCas9-VP64	positive selection	2567948
39313449	39313472	21	+	27260157	DLD1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.64827204503935	[]	[]	8	hSpCas9	negative selection	2575324
39270414	39270437	21	-	27260157	DLD1	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.554200860712802	[]	[]	-4	hSpCas9	negative selection	2578319
39264561	39264584	21	+	27260157	DLD1	viability	ACATCTACCAAGAATGGTGGAGG	BRWD1	ENSG00000185658	0.355278894005336	[]	[]	4	hSpCas9	negative selection	2580567
39298513	39298536	21	-	27260157	DLD1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.346494936569452	[]	[]	-3	hSpCas9	negative selection	2581798
39255708	39255731	21	+	27260157	DLD1	viability	TCTGTAGCAATCTGACTGCGTGG	BRWD1	ENSG00000185658	-0.853440865164795	[]	[]	-6	hSpCas9	negative selection	2582364
39313436	39313459	21	+	27260157	DLD1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.397433925025113	[]	[]	4	hSpCas9	negative selection	2584744
39313239	39313262	21	+	27260157	DLD1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	1.24594491196907	[]	[]	9	hSpCas9	negative selection	2585103
39313246	39313269	21	-	27260157	DLD1	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.0417313001880198	[]	[]	0	hSpCas9	negative selection	2587197
39278757	39278780	21	+	27260157	DLD1	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.231986398633438	[]	[]	3	hSpCas9	negative selection	2587212
39313460	39313483	21	+	27260157	DLD1	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	0.771780261038955	[]	[]	8	hSpCas9	negative selection	2613143
39255689	39255712	21	-	27260157	DLD1	viability	CAGAACGTGACCTGCAGGCTTGG	BRWD1	ENSG00000185658	0.640275629637854	[]	[]	8	hSpCas9	negative selection	2613901
39313442	39313465	21	-	27260157	DLD1	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.361599300203624	[]	[]	4	hSpCas9	negative selection	2619154
39313253	39313276	21	-	27260157	DLD1	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	-1.01612151786763	[]	[]	-7	hSpCas9	negative selection	2621313
39313277	39313300	21	-	27260157	DLD1	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.804971695350833	[]	[]	-6	hSpCas9	negative selection	2645277
39313267	39313290	21	+	27260157	DLD1	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-1.47284262730352	[]	[]	-8	hSpCas9	negative selection	2645634
39255756	39255779	21	-	27260157	DLD1	viability	CGTCGTAGTGGACAAGTTGAAGG	BRWD1	ENSG00000185658	-0.523018063553287	[]	[]	-4	hSpCas9	negative selection	2646384
39313471	39313494	21	+	27260157	DLD1	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.0836454214962887	[]	[]	3	hSpCas9	negative selection	2647768
39313442	39313465	21	+	27260157	DLD1	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.0146990814354705	[]	[]	0	hSpCas9	negative selection	2649022
39313449	39313472	21	+	27260157	HT1080	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	-0.0654992002539699	[]	[]	0	hSpCas9	negative selection	2651454
39270414	39270437	21	-	27260157	HT1080	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.337829795671652	[]	[]	-7	hSpCas9	negative selection	2654449
39264561	39264584	21	+	27260157	HT1080	viability	ACATCTACCAAGAATGGTGGAGG	BRWD1	ENSG00000185658	0.241165514688474	[]	[]	2	hSpCas9	negative selection	2656697
39298513	39298536	21	-	27260157	HT1080	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.291876958010046	[]	[]	-7	hSpCas9	negative selection	2657928
39255708	39255731	21	+	27260157	HT1080	viability	TCTGTAGCAATCTGACTGCGTGG	BRWD1	ENSG00000185658	-0.327426583258116	[]	[]	-7	hSpCas9	negative selection	2658494
39313436	39313459	21	+	27260157	HT1080	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.270841572608668	[]	[]	2	hSpCas9	negative selection	2660874
39313239	39313262	21	+	27260157	HT1080	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.9273380176273	[]	[]	7	hSpCas9	negative selection	2661233
39313246	39313269	21	-	27260157	HT1080	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.160696665845832	[]	[]	0	hSpCas9	negative selection	2663327
39278757	39278780	21	+	27260157	HT1080	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.298747141654823	[]	[]	3	hSpCas9	negative selection	2663342
39313460	39313483	21	+	27260157	HT1080	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	0.589146632523194	[]	[]	5	hSpCas9	negative selection	2689273
39255689	39255712	21	-	27260157	HT1080	viability	CAGAACGTGACCTGCAGGCTTGG	BRWD1	ENSG00000185658	0.200748515044523	[]	[]	2	hSpCas9	negative selection	2690031
39313442	39313465	21	-	27260157	HT1080	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.844375086006282	[]	[]	7	hSpCas9	negative selection	2695284
39313253	39313276	21	-	27260157	HT1080	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	0.399620034283964	[]	[]	3	hSpCas9	negative selection	2697443
39313277	39313300	21	-	27260157	HT1080	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.598743558179251	[]	[]	-7	hSpCas9	negative selection	2721407
39313267	39313290	21	+	27260157	HT1080	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-1.03019718465179	[]	[]	-8	hSpCas9	negative selection	2721764
39255756	39255779	21	-	27260157	HT1080	viability	CGTCGTAGTGGACAAGTTGAAGG	BRWD1	ENSG00000185658	0.0557689540521954	[]	[]	0	hSpCas9	negative selection	2722514
39313471	39313494	21	+	27260157	HT1080	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.230098195991698	[]	[]	2	hSpCas9	negative selection	2723898
39313442	39313465	21	+	27260157	HT1080	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.543273804928426	[]	[]	5	hSpCas9	negative selection	2725152
39313449	39313472	21	+	27260157	MKN45	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.29588011610469	[]	[]	5	hSpCas9	negative selection	2727584
39270414	39270437	21	-	27260157	MKN45	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.691754422530859	[]	[]	-7	hSpCas9	negative selection	2730579
39264561	39264584	21	+	27260157	MKN45	viability	ACATCTACCAAGAATGGTGGAGG	BRWD1	ENSG00000185658	-0.361084495182164	[]	[]	-1	hSpCas9	negative selection	2732827
39298513	39298536	21	-	27260157	MKN45	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.697562860903873	[]	[]	-7	hSpCas9	negative selection	2734058
39255708	39255731	21	+	27260157	MKN45	viability	TCTGTAGCAATCTGACTGCGTGG	BRWD1	ENSG00000185658	-0.461416482758683	[]	[]	-6	hSpCas9	negative selection	2734624
39313436	39313459	21	+	27260157	MKN45	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-0.547546225357706	[]	[]	-6	hSpCas9	negative selection	2737004
39313239	39313262	21	+	27260157	MKN45	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.646608391041185	[]	[]	7	hSpCas9	negative selection	2737363
39313246	39313269	21	-	27260157	MKN45	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.0967932695622772	[]	[]	0	hSpCas9	negative selection	2739457
39278757	39278780	21	+	27260157	MKN45	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.74657772534664	[]	[]	9	hSpCas9	negative selection	2739472
39313460	39313483	21	+	27260157	MKN45	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	-0.155142393578667	[]	[]	0	hSpCas9	negative selection	2765403
39255689	39255712	21	-	27260157	MKN45	viability	CAGAACGTGACCTGCAGGCTTGG	BRWD1	ENSG00000185658	1.04235978951689	[]	[]	8	hSpCas9	negative selection	2766161
39313442	39313465	21	-	27260157	MKN45	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.0624370720736767	[]	[]	0	hSpCas9	negative selection	2771414
39313253	39313276	21	-	27260157	MKN45	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	0.755388062051008	[]	[]	7	hSpCas9	negative selection	2773573
39313277	39313300	21	-	27260157	MKN45	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-1.72327895734315	[]	[]	-9	hSpCas9	negative selection	2797537
39313267	39313290	21	+	27260157	MKN45	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-2.05582466563122	[]	[]	-9	hSpCas9	negative selection	2797894
39255756	39255779	21	-	27260157	MKN45	viability	CGTCGTAGTGGACAAGTTGAAGG	BRWD1	ENSG00000185658	-0.452702801757511	[]	[]	-6	hSpCas9	negative selection	2798644
39313471	39313494	21	+	27260157	MKN45	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	1.33779082842098	[]	[]	9	hSpCas9	negative selection	2800028
39313442	39313465	21	+	27260157	MKN45	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.469465348259408	[]	[]	6	hSpCas9	negative selection	2801282
39313449	39313472	21	+	27260157	RKO	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.211804881738795	[]	[]	1	hSpCas9	negative selection	2803714
39270414	39270437	21	-	27260157	RKO	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.146474150343876	[]	[]	0	hSpCas9	negative selection	2806709
39264561	39264584	21	+	27260157	RKO	viability	ACATCTACCAAGAATGGTGGAGG	BRWD1	ENSG00000185658	-0.661174703741951	[]	[]	-7	hSpCas9	negative selection	2808957
39298513	39298536	21	-	27260157	RKO	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.24492970594867	[]	[]	1	hSpCas9	negative selection	2810188
39255708	39255731	21	+	27260157	RKO	viability	TCTGTAGCAATCTGACTGCGTGG	BRWD1	ENSG00000185658	0.486476540588892	[]	[]	2	hSpCas9	negative selection	2810754
39313436	39313459	21	+	27260157	RKO	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-0.076509515351649	[]	[]	0	hSpCas9	negative selection	2813134
39313239	39313262	21	+	27260157	RKO	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.729767428555633	[]	[]	8	hSpCas9	negative selection	2813493
39313246	39313269	21	-	27260157	RKO	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.74497414712044	[]	[]	8	hSpCas9	negative selection	2815587
39278757	39278780	21	+	27260157	RKO	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.08812111531073	[]	[]	9	hSpCas9	negative selection	2815602
39313460	39313483	21	+	27260157	RKO	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	-0.31670390011712	[]	[]	-6	hSpCas9	negative selection	2841533
39255689	39255712	21	-	27260157	RKO	viability	CAGAACGTGACCTGCAGGCTTGG	BRWD1	ENSG00000185658	0.550597135693811	[]	[]	3	hSpCas9	negative selection	2842291
39313442	39313465	21	-	27260157	RKO	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.48004159295574	[]	[]	2	hSpCas9	negative selection	2847544
39313253	39313276	21	-	27260157	RKO	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	-2.95190497616218	[]	[]	-9	hSpCas9	negative selection	2849703
39313277	39313300	21	-	27260157	RKO	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.24457696603758	[]	[]	1	hSpCas9	negative selection	2873667
39313267	39313290	21	+	27260157	RKO	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-1.2002662423595	[]	[]	-8	hSpCas9	negative selection	2874024
39255756	39255779	21	-	27260157	RKO	viability	CGTCGTAGTGGACAAGTTGAAGG	BRWD1	ENSG00000185658	-0.387785954565474	[]	[]	-6	hSpCas9	negative selection	2874774
39313471	39313494	21	+	27260157	RKO	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.463562866431867	[]	[]	2	hSpCas9	negative selection	2876158
39313442	39313465	21	+	27260157	RKO	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.533231482707665	[]	[]	3	hSpCas9	negative selection	2877412
39313449	39313472	21	+	27260157	SF268	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.0914849341796244	[]	[]	0	hSpCas9	negative selection	2879844
39270414	39270437	21	-	27260157	SF268	viability	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.228180576376928	[]	[]	-2	hSpCas9	negative selection	2882839
39264561	39264584	21	+	27260157	SF268	viability	ACATCTACCAAGAATGGTGGAGG	BRWD1	ENSG00000185658	0.359422692289993	[]	[]	4	hSpCas9	negative selection	2885087
39298513	39298536	21	-	27260157	SF268	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.581414099498435	[]	[]	-4	hSpCas9	negative selection	2886318
39255708	39255731	21	+	27260157	SF268	viability	TCTGTAGCAATCTGACTGCGTGG	BRWD1	ENSG00000185658	0.111912188566051	[]	[]	0	hSpCas9	negative selection	2886884
39313436	39313459	21	+	27260157	SF268	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.0307471039826517	[]	[]	0	hSpCas9	negative selection	2889264
39313239	39313262	21	+	27260157	SF268	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.710740744108723	[]	[]	8	hSpCas9	negative selection	2889623
39313246	39313269	21	-	27260157	SF268	viability	GGCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.126028974423382	[]	[]	0	hSpCas9	negative selection	2891717
39278757	39278780	21	+	27260157	SF268	viability	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.928950159697112	[]	[]	9	hSpCas9	negative selection	2891732
39313460	39313483	21	+	27260157	SF268	viability	ACCGGGCGTCGGGCGGACGACGG	BRWD1	ENSG00000185658	0.272040316190051	[]	[]	4	hSpCas9	negative selection	2917663
39255689	39255712	21	-	27260157	SF268	viability	CAGAACGTGACCTGCAGGCTTGG	BRWD1	ENSG00000185658	1.03131191524179	[]	[]	9	hSpCas9	negative selection	2918421
39313442	39313465	21	-	27260157	SF268	viability	CCGGTGCCTCTCATCGAGTCGGG	BRWD1	ENSG00000185658	0.489808795938818	[]	[]	7	hSpCas9	negative selection	2923674
39313253	39313276	21	-	27260157	SF268	viability	ACCTATCGGCGGGCCCGTGTCGG	BRWD1	ENSG00000185658	-0.150776197068796	[]	[]	-1	hSpCas9	negative selection	2925833
39313277	39313300	21	-	27260157	SF268	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.203170343378135	[]	[]	3	hSpCas9	negative selection	2949797
39313267	39313290	21	+	27260157	SF268	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-1.34420716898012	[]	[]	-7	hSpCas9	negative selection	2950154
39255756	39255779	21	-	27260157	SF268	viability	CGTCGTAGTGGACAAGTTGAAGG	BRWD1	ENSG00000185658	-0.791454443024635	[]	[]	-6	hSpCas9	negative selection	2950904
39313471	39313494	21	+	27260157	SF268	viability	GGCGGACGACGGCTCCGCCATGG	BRWD1	ENSG00000185658	0.131327405873146	[]	[]	0	hSpCas9	negative selection	2952288
39313442	39313465	21	+	27260157	SF268	viability	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.181431344529402	[]	[]	0	hSpCas9	negative selection	2953542
39313277	39313300	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.16377078729884703	[5,5]	[5,4]	3	hSpCas9	positive selection	2973765
39313267	39313290	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	-0.5849352179969675	[3,3]	[3,0]	-7	hSpCas9	positive selection	2973766
39313437	39313460	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-0.5264517501656176	[2,3]	[3,0]	-6	hSpCas9	positive selection	2973767
39313264	39313287	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	0.021453659303188613	[3,3]	[2,2]	0	hSpCas9	positive selection	2973768
39313277	39313300	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.4729673118969867	[5,5]	[4,5]	7	hSpCas9	positive selection	3041623
39313267	39313290	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	0.02370552443825248	[3,3]	[2,2]	0	hSpCas9	positive selection	3041624
39313437	39313460	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.5174687194095055	[2,2]	[3,3]	8	hSpCas9	positive selection	3041625
39313264	39313287	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	-0.11077047253917341	[3,3]	[1,1]	-2	hSpCas9	positive selection	3041626
39313239	39313262		+	24336571	A375	resistance to PLX after 7 days	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.19589378382619893	[43,53]	[45,38]	-6	hSpCas9	positive selection	3151804
39313267	39313290		+	24336571	A375	resistance to PLX after 7 days	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.14505212486741936	[17,17]	[17,21]	4	hSpCas9	positive selection	3151815
39313089	39313112		-	24336571	A375	resistance to PLX after 7 days	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.10736837507466568	[42,43]	[40,38]	-3	hSpCas9	positive selection	3151823
39313239	39313262		+	24336571	A375	resistance to PLX after 14 days	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.10333353805056777	[60,53]	[22,25]	-1	hSpCas9	positive selection	3209597
39313267	39313290		+	24336571	A375	resistance to PLX after 14 days	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.3263716740907373	[14,16]	[9,8]	3	hSpCas9	positive selection	3209608
39313089	39313112		-	24336571	A375	resistance to PLX after 14 days	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.677599570049032	[55,40]	[13,13]	-7	hSpCas9	positive selection	3209616
39313239	39313262		+	24336571	A375	viability after 7 days	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.16790476843643343	[45]	[43,53]	2	hSpCas9	negative selection	3267390
39313267	39313290		+	24336571	A375	viability after 7 days	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.05748988871958649	[19]	[17,17]	-1	hSpCas9	negative selection	3267401
39313089	39313112		-	24336571	A375	viability after 7 days	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.08448669132304776	[42]	[42,43]	1	hSpCas9	negative selection	3267409
39313239	39313262		+	24336571	A375	viability after 14 days	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.42044509796299945	[45]	[60,53]	5	hSpCas9	negative selection	3325183
39313267	39313290		+	24336571	A375	viability after 14 days	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.19350188851527517	[19]	[14,16]	-2	hSpCas9	negative selection	3325194
39313089	39313112		-	24336571	A375	viability after 14 days	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.24903591740059983	[42]	[55,40]	3	hSpCas9	negative selection	3325202
39313239	39313262	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.6812309484789016	[81,108]	[0,0]	3	hSpCas9	positive selection	3339134
39313277	39313300	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.296409731521836	[170,204]	[0,0]	-2	hSpCas9	positive selection	3339135
39312882	39312905	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	8.274925630399672	[99,107]	[0,419]	9	hSpCas9	positive selection	3339136
39313089	39313112	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.9535454632687321	[78,78]	[0,0]	4	hSpCas9	positive selection	3358375
39312872	39312895	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	-1.8248228299080365	[541,541]	[0,0]	-9	hSpCas9	positive selection	3358376
39313267	39313290	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3358377
39313277	39313300	21	-	26780180	HT29	viability (Avana library 4 designs)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.0284058759484418	[]	[]	0	hSpCas9	negative selection	3409966
39313267	39313290	21	-	26780180	HT29	viability (Avana library 4 designs)	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	1.67686076499719	[]	[]	6	hSpCas9	negative selection	3409967
39313436	39313459	21	+	26780180	HT29	viability (Avana library 4 designs)	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	1.44108538024402	[]	[]	5	hSpCas9	negative selection	3409968
39313264	39313287	21	-	26780180	HT29	viability (Avana library 4 designs)	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	2.43152092585305	[]	[]	8	hSpCas9	negative selection	3409969
39313267	39313290	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	2.27207465296865	[]	[]	3	hSpCas9	negative selection	3484236
39313436	39313459	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	6.55339740654647	[]	[]	9	hSpCas9	negative selection	3484237
39313264	39313287	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	3.64132568903908	[]	[]	6	hSpCas9	negative selection	3484238
39313277	39313300	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	2.15820013140322	[]	[]	3	hSpCas9	negative selection	3484239
39313461	39313484	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGTCGTCCGCCCGACGCCCGG	BRWD1	ENSG00000185658	2.86725240100389	[]	[]	4	hSpCas9	negative selection	3484240
39313453	39313476	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAGGCACCGGGCGTCGGGCGG	BRWD1	ENSG00000185658	4.31009362313339	[]	[]	7	hSpCas9	negative selection	3484241
39313267	39313290	21	-	26780180	A375	viability (Avana lentiGuide)	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	-4.50485278080031	[]	[]	-7	hSpCas9	negative selection	3592895
39313436	39313459	21	+	26780180	A375	viability (Avana lentiGuide)	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-3.93814173562784	[]	[]	-6	hSpCas9	negative selection	3592896
39313264	39313287	21	-	26780180	A375	viability (Avana lentiGuide)	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	1.10477208553713	[]	[]	1	hSpCas9	negative selection	3592897
39313277	39313300	21	-	26780180	A375	viability (Avana lentiGuide)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-3.44724194613033	[]	[]	-6	hSpCas9	negative selection	3592898
39313461	39313484	21	-	26780180	A375	viability (Avana lentiGuide)	GCCGTCGTCCGCCCGACGCCCGG	BRWD1	ENSG00000185658	-1.00785867445587	[]	[]	-1	hSpCas9	negative selection	3592899
39313453	39313476	21	+	26780180	A375	viability (Avana lentiGuide)	GAGAGGCACCGGGCGTCGGGCGG	BRWD1	ENSG00000185658	-3.11053521835504	[]	[]	-5	hSpCas9	negative selection	3592900
39313267	39313290	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	-0.09304422864514122	[4]	[4,3]	-1	hSpCas9	positive selection	3701554
39313436	39313459	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.20335820681333575	[5]	[5,5]	5	hSpCas9	positive selection	3701555
39313264	39313287	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	0.12665995374077763	[4]	[5,5]	3	hSpCas9	positive selection	3701556
39313277	39313300	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.13592361971047556	[6]	[6,7]	3	hSpCas9	positive selection	3701557
39313461	39313484	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGTCGTCCGCCCGACGCCCGG	BRWD1	ENSG00000185658	0.2486368572884251	[3]	[5,3]	7	hSpCas9	positive selection	3701558
39313453	39313476	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAGGCACCGGGCGTCGGGCGG	BRWD1	ENSG00000185658	0.23349803422842716	[4]	[6,5]	6	hSpCas9	positive selection	3701559
39313267	39313290	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTATCGCCCGGTACCTATCGG	BRWD1	ENSG00000185658	0.23784800757790076	[5]	[6,4]	6	hSpCas9	positive selection	3810161
39313436	39313459	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.14904970601377945	[5]	[5,4]	3	hSpCas9	positive selection	3810162
39313264	39313287	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCGCCCGGTACCTATCGGCGG	BRWD1	ENSG00000185658	-0.684744127072771	[5]	[3,0]	-7	hSpCas9	positive selection	3810163
39313277	39313300	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.2813771341554563	[7]	[7,7]	7	hSpCas9	positive selection	3810164
39313461	39313484	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGTCGTCCGCCCGACGCCCGG	BRWD1	ENSG00000185658	-0.11091828562205217	[5]	[4,3]	-1	hSpCas9	positive selection	3810165
39313453	39313476	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAGGCACCGGGCGTCGGGCGG	BRWD1	ENSG00000185658	0.1646830373359388	[5]	[5,6]	4	hSpCas9	positive selection	3810166
39313239	39313262	21	+	26780180	A375	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.884623498709729	[]	[]	4	hSpCas9	negative selection	3918436
39313277	39313300	21	-	26780180	A375	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.864392882205857	[]	[]	3	hSpCas9	negative selection	3918437
39312882	39312905	21	-	26780180	A375	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.808383255296163	[]	[]	3	hSpCas9	negative selection	3918438
39312872	39312895	21	+	26780180	A375	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.181494302244875	[]	[]	0	hSpCas9	negative selection	3918439
39313267	39313290	21	+	26780180	A375	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	1.3091002407352	[]	[]	7	hSpCas9	negative selection	3918440
39313089	39313112	21	-	26780180	A375	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.49397333805487	[]	[]	8	hSpCas9	negative selection	3918441
39313239	39313262	21	+	26780180	HT29	viability (GeCKOv2 library)	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.944542886802304	[]	[]	4	hSpCas9	negative selection	4026402
39313277	39313300	21	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.659724233875492	[]	[]	2	hSpCas9	negative selection	4026403
39312882	39312905	21	-	26780180	HT29	viability (GeCKOv2 library)	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.785121073181464	[]	[]	3	hSpCas9	negative selection	4026404
39312872	39312895	21	+	26780180	HT29	viability (GeCKOv2 library)	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	-0.230100802184138	[]	[]	-6	hSpCas9	negative selection	4026405
39313267	39313290	21	+	26780180	HT29	viability (GeCKOv2 library)	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	1.39807369665668	[]	[]	7	hSpCas9	negative selection	4026406
39313089	39313112	21	-	26780180	HT29	viability (GeCKOv2 library)	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.95135164277115	[]	[]	9	hSpCas9	negative selection	4026407
39313239	39313262	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	1.0006033622089943	[5]	[12,4]	9	hSpCas9	positive selection	4178329
39313267	39313290	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.03350633411623957	[4]	[2,3]	0	hSpCas9	positive selection	4178340
39313089	39313112	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.13806750168788673	[5]	[4,3]	3	hSpCas9	positive selection	4178350
39313239	39313262	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.8401093627551571	[5]	[4,4,3,3]	5	hSpCas9	positive selection	4242351
39313267	39313290	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.5860128593336033	[3]	[4,4,1,0]	4	hSpCas9	positive selection	4242362
39313089	39313112	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.31596447112824755	[5]	[0,3,1,3]	2	hSpCas9	positive selection	4242372
39313239	39313262	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.049581416546368995	[2]	[2,1]	-1	hSpCas9	positive selection	4258555
39313277	39313300	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.16333189076019505	[3]	[2,1]	-3	hSpCas9	positive selection	4258556
39312882	39312905	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.13430283330544146	[2]	[1,0]	-3	hSpCas9	positive selection	4258557
39313089	39313112	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.48054040957651534	[2]	[2,0]	-8	hSpCas9	positive selection	4322839
39312872	39312895	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.25849194940062814	[4]	[4,3]	5	hSpCas9	positive selection	4322840
39313267	39313290	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.8221399184891744	[1]	[0,0]	-9	hSpCas9	positive selection	4322841
39298514	39298536	21	+	27760321	OCIAML3	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.056784726327432034	[826,676]	[510,629]	0	hSpCas9	negative selection	4382346
39312846	39312868	21	-	27760321	OCIAML3	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	-0.14854894794004878	[381,355]	[190,350]	-1	hSpCas9	negative selection	4382347
39312877	39312899	21	-	27760321	OCIAML3	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.5800017081348372	[369,296]	[345,441]	7	hSpCas9	negative selection	4382348
39313246	39313268	21	-	27760321	OCIAML3	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.527877862561593	[26,404]	[227,305]	6	hSpCas9	negative selection	4382349
39313263	39313285	21	-	27760321	OCIAML3	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.2452908461941018	[959,892]	[515,735]	-3	hSpCas9	negative selection	4382350
39298514	39298536	21	+	27760321	OCIAML2	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.01859315260806349	[826,676]	[446,795]	0	hSpCas9	negative selection	4465809
39312846	39312868	21	-	27760321	OCIAML2	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.06002579689453211	[381,355]	[265,370]	0	hSpCas9	negative selection	4465810
39312877	39312899	21	-	27760321	OCIAML2	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.8930336739559643	[369,296]	[99,202]	-7	hSpCas9	negative selection	4465811
39313246	39313268	21	-	27760321	OCIAML2	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.016000706840916035	[26,404]	[174,199]	0	hSpCas9	negative selection	4465812
39313263	39313285	21	-	27760321	OCIAML2	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-1.0666498982610586	[959,892]	[344,374]	-7	hSpCas9	negative selection	4465813
39298514	39298536	21	+	27760321	MV411	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	0.6018836850352836	[826,676]	[818,644]	4	hSpCas9	negative selection	4549272
39312846	39312868	21	-	27760321	MV411	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.4266985475200858	[381,355]	[368,264]	3	hSpCas9	negative selection	4549273
39312877	39312899	21	-	27760321	MV411	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.021110885620097053	[369,296]	[279,134]	0	hSpCas9	negative selection	4549274
39313246	39313268	21	-	27760321	MV411	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.136987567231039	[26,404]	[94,205]	-1	hSpCas9	negative selection	4549275
39313263	39313285	21	-	27760321	MV411	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.341015624033042	[959,892]	[292,767]	-2	hSpCas9	negative selection	4549276
39298514	39298536	21	+	27760321	HL60	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.9678131823860614	[826,676]	[263,363]	-7	hSpCas9	negative selection	4632735
39312846	39312868	21	-	27760321	HL60	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	-0.39660863492524134	[381,355]	[280,173]	-4	hSpCas9	negative selection	4632736
39312877	39312899	21	-	27760321	HL60	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.39786165726443656	[369,296]	[191,219]	-4	hSpCas9	negative selection	4632737
39313246	39313268	21	-	27760321	HL60	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.0950937939010893	[26,404]	[156,250]	1	hSpCas9	negative selection	4632738
39313263	39313285	21	-	27760321	HL60	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.583784427466999	[959,892]	[525,482]	-6	hSpCas9	negative selection	4632739
39298514	39298536	21	+	27760321	HT1080	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.21585635589598462	[676,527]	[230,179]	-1	hSpCas9	negative selection	4716198
39312846	39312868	21	-	27760321	HT1080	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.06602940936297817	[355,277]	[146,115]	0	hSpCas9	negative selection	4716199
39312877	39312899	21	-	27760321	HT1080	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.7111989102393634	[296,231]	[214,125]	4	hSpCas9	negative selection	4716200
39313246	39313268	21	-	27760321	HT1080	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.27864967866474205	[404,315]	[115,120]	-1	hSpCas9	negative selection	4716201
39313263	39313285	21	-	27760321	HT1080	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.38076073282138345	[892,696]	[300,179]	-2	hSpCas9	negative selection	4716202
39298514	39298536	21	+	27760321	HT29	viability after 7 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.19683553078088523	[676,527]	[591,920,506]	-3	hSpCas9	negative selection	4799661
39312846	39312868	21	-	27760321	HT29	viability after 7 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.18402405659465804	[355,277]	[839,323,283]	3	hSpCas9	negative selection	4799662
39312877	39312899	21	-	27760321	HT29	viability after 7 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.29433316735661486	[296,231]	[456,500,301]	4	hSpCas9	negative selection	4799663
39313246	39313268	21	-	27760321	HT29	viability after 7 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.3677684933674757	[404,315]	[762,523,531]	5	hSpCas9	negative selection	4799664
39313263	39313285	21	-	27760321	HT29	viability after 7 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.093827188169751	[892,696]	[1101,815,973]	-1	hSpCas9	negative selection	4799665
39298514	39298536	21	+	27760321	HT29	viability after 25 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.49891864181694345	[676,527]	[226,515,762]	-4	hSpCas9	negative selection	4883124
39312846	39312868	21	-	27760321	HT29	viability after 25 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.4102932681516253	[355,277]	[560,487,378]	4	hSpCas9	negative selection	4883125
39312877	39312899	21	-	27760321	HT29	viability after 25 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.22558530420510964	[296,231]	[342,419,290]	2	hSpCas9	negative selection	4883126
39313246	39313268	21	-	27760321	HT29	viability after 25 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.7101983690678721	[404,315]	[650,554,832]	7	hSpCas9	negative selection	4883127
39313263	39313285	21	-	27760321	HT29	viability after 25 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.12777327763541968	[892,696]	[854,588,1072]	-1	hSpCas9	negative selection	4883128
39298514	39298536	21	+	27760321	HT29	viability after 22 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.4681150433893876	[676,527]	[432,719,357]	-4	hSpCas9	negative selection	4966587
39312846	39312868	21	-	27760321	HT29	viability after 22 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.19317383938220412	[355,277]	[351,566,338]	2	hSpCas9	negative selection	4966588
39312877	39312899	21	-	27760321	HT29	viability after 22 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.4610842967884883	[296,231]	[104,297,266]	-4	hSpCas9	negative selection	4966589
39313246	39313268	21	-	27760321	HT29	viability after 22 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.7929141452820623	[404,315]	[410,781,983]	8	hSpCas9	negative selection	4966590
39313263	39313285	21	-	27760321	HT29	viability after 22 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.20721700391889242	[892,696]	[580,815,998]	-2	hSpCas9	negative selection	4966591
39298514	39298536	21	+	27760321	HT29	viability after 19 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.5477077351005989	[676,527]	[544,203,664]	-5	hSpCas9	negative selection	5050050
39312846	39312868	21	-	27760321	HT29	viability after 19 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.2820571058122684	[355,277]	[515,316,494]	2	hSpCas9	negative selection	5050051
39312877	39312899	21	-	27760321	HT29	viability after 19 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.07647430083384754	[296,231]	[256,490,115]	0	hSpCas9	negative selection	5050052
39313246	39313268	21	-	27760321	HT29	viability after 19 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.8638269421025847	[404,315]	[419,781,1003]	8	hSpCas9	negative selection	5050053
39313263	39313285	21	-	27760321	HT29	viability after 19 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.21825017312145545	[892,696]	[933,559,862]	-2	hSpCas9	negative selection	5050054
39298514	39298536	21	+	27760321	HT29	viability after 16 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.3599083277246279	[676,527]	[604,453,525]	-4	hSpCas9	negative selection	5133513
39312846	39312868	21	-	27760321	HT29	viability after 16 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.22316201283580078	[355,277]	[519,450,279]	2	hSpCas9	negative selection	5133514
39312877	39312899	21	-	27760321	HT29	viability after 16 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.4048725384127122	[296,231]	[228,148,294]	-4	hSpCas9	negative selection	5133515
39313246	39313268	21	-	27760321	HT29	viability after 16 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.3040537779452933	[404,315]	[614,260,634]	3	hSpCas9	negative selection	5133516
39313263	39313285	21	-	27760321	HT29	viability after 16 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.22522863152241068	[892,696]	[973,518,815]	-3	hSpCas9	negative selection	5133517
39298514	39298536	21	+	27760321	HT29	viability after 13 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.32361524073778525	[676,527]	[624,470,577]	-4	hSpCas9	negative selection	5216976
39312846	39312868	21	-	27760321	HT29	viability after 13 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.5127484603460294	[355,277]	[644,390,536]	6	hSpCas9	negative selection	5216977
39312877	39312899	21	-	27760321	HT29	viability after 13 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.06209902203865153	[296,231]	[339,300,319]	0	hSpCas9	negative selection	5216978
39313246	39313268	21	-	27760321	HT29	viability after 13 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.727208267213479	[404,315]	[683,651,737]	8	hSpCas9	negative selection	5216979
39313263	39313285	21	-	27760321	HT29	viability after 13 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.04235271292210596	[892,696]	[920,876,888]	0	hSpCas9	negative selection	5216980
39298514	39298536	21	+	27760321	HT29	viability after 10 days	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.6066183694193997	[676,527]	[509,527,445]	-6	hSpCas9	negative selection	5300439
39312846	39312868	21	-	27760321	HT29	viability after 10 days	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	0.21573701492144737	[355,277]	[453,544,383]	3	hSpCas9	negative selection	5300440
39312877	39312899	21	-	27760321	HT29	viability after 10 days	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	0.40644703438284135	[296,231]	[283,523,505]	5	hSpCas9	negative selection	5300441
39313246	39313268	21	-	27760321	HT29	viability after 10 days	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	0.3812943483497305	[404,315]	[473,582,698]	5	hSpCas9	negative selection	5300442
39313263	39313285	21	-	27760321	HT29	viability after 10 days	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	-0.09852033896282042	[892,696]	[886,922,969]	-1	hSpCas9	negative selection	5300443
39298514	39298536	21	+	27760321	MOLM13	viability	CAACATAGGACCGATGCGCTGG	BRWD1	ENSG00000185658	-0.23319665455809602	[826,676]	[692,74]	-1	hSpCas9	negative selection	5383902
39312846	39312868	21	-	27760321	MOLM13	viability	GAGCACAACAGGAGCTACGAGG	BRWD1	ENSG00000185658	-1.1918726205656769	[381,355]	[135,52]	-6	hSpCas9	negative selection	5383903
39312877	39312899	21	-	27760321	MOLM13	viability	GTTGCCGAAGAGATTGGACTGG	BRWD1	ENSG00000185658	-0.4652833565183462	[369,296]	[94,169]	-3	hSpCas9	negative selection	5383904
39313246	39313268	21	-	27760321	MOLM13	viability	GCGGGCCCGTGTCGGAGAGCGG	BRWD1	ENSG00000185658	-0.7947713226676736	[26,404]	[128,29]	-5	hSpCas9	negative selection	5383905
39313263	39313285	21	-	27760321	MOLM13	viability	TCGCCCGGTACCTATCGGCGGG	BRWD1	ENSG00000185658	1.833433125296163	[959,892]	[3806,208]	9	hSpCas9	negative selection	5383906
39313563	39313586	21	+	27661255	K562	viability	GGCTGGCGTCCCCTCTTCTCAGG	BRWD1	ENSG00000185658	0.17324489993452352	[406,356]	[359,331]	6	dCas9-KRAB	negative selection	5465566
39313239	39313262	21	+	27260156	BXPC3	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.215836243224947	[366]	[421,510,383,461]	5	hSpCas9	negative selection	5531015
39313277	39313300	21	-	27260156	BXPC3	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.3010944173156065	[561]	[580,669,868,801]	6	hSpCas9	negative selection	5531016
39312882	39312905	21	-	27260156	BXPC3	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.41231675763364006	[244]	[283,405,343,327]	8	hSpCas9	negative selection	5531017
39313089	39313112	21	-	27260156	BXPC3	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.3417734753525827	[369]	[256,228,333,423]	-6	hSpCas9	negative selection	5595299
39312872	39312895	21	+	27260156	BXPC3	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.612402148233222	[1024]	[1469,1636,1717,1750]	9	hSpCas9	negative selection	5595300
39313267	39313290	21	+	27260156	BXPC3	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.10169105960677749	[194]	[221,259,150,238]	2	hSpCas9	negative selection	5595301
39313239	39313262	21	+	27260156	A673	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.19359903246555632	[366]	[530,493,493,498]	4	hSpCas9	negative selection	5652266
39313277	39313300	21	-	27260156	A673	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.2684319624664434	[561]	[840,824,786,798]	6	hSpCas9	negative selection	5652267
39312882	39312905	21	-	27260156	A673	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.3093678360823102	[244]	[467,401,315,277]	7	hSpCas9	negative selection	5652268
39313089	39313112	21	-	27260156	A673	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.36452840676441883	[369]	[441,261,328,360]	-7	hSpCas9	negative selection	5716550
39312872	39312895	21	+	27260156	A673	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.570597313797812	[1024]	[2095,1712,1803,1722]	9	hSpCas9	negative selection	5716551
39313267	39313290	21	+	27260156	A673	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.3219395856545808	[194]	[283,129,200,143]	-7	hSpCas9	negative selection	5716552
39313239	39313262	21	+	27260156	A375	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.5530093013707983	[366]	[623,584,696,603]	7	hSpCas9	negative selection	5773517
39313277	39313300	21	-	27260156	A375	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.2652076789186366	[561]	[903,875,749,651]	4	hSpCas9	negative selection	5773518
39312882	39312905	21	-	27260156	A375	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.19910763499801865	[244]	[347,303,222,422]	3	hSpCas9	negative selection	5773519
39313089	39313112	21	-	27260156	A375	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.2614935634557501	[369]	[517,407,305,231]	-4	hSpCas9	negative selection	5837801
39312872	39312895	21	+	27260156	A375	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.83262298242216	[1024]	[2045,2546,2044,1959]	9	hSpCas9	negative selection	5837802
39313267	39313290	21	+	27260156	A375	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.7626220515886797	[194]	[216,94,88,130]	-7	hSpCas9	negative selection	5837803
39313239	39313262	21	+	27260156	COLO741	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.05301863740266183	[366]	[492,449,417]	-1	hSpCas9	negative selection	5894768
39313277	39313300	21	-	27260156	COLO741	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.0822868427562683	[561]	[882,741,670]	1	hSpCas9	negative selection	5894769
39312882	39312905	21	-	27260156	COLO741	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.4656909404986747	[244]	[557,422,332]	8	hSpCas9	negative selection	5894770
39313089	39313112	21	-	27260156	COLO741	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.7744359074166072	[369]	[328,298,209]	-9	hSpCas9	negative selection	5959052
39312872	39312895	21	+	27260156	COLO741	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.4189502276231505	[1024]	[1843,1750,1667]	8	hSpCas9	negative selection	5959053
39313267	39313290	21	+	27260156	COLO741	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.4780532138146465	[194]	[212,229,101]	-7	hSpCas9	negative selection	5959054
39313239	39313262	21	+	27260156	CAL120	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.17180132448321286	[366]	[656,528,380]	2	hSpCas9	negative selection	6016019
39313277	39313300	21	-	27260156	CAL120	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.24058902469797272	[561]	[799,932,742]	3	hSpCas9	negative selection	6016020
39312882	39312905	21	-	27260156	CAL120	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.09403571477033201	[244]	[327,407,241]	1	hSpCas9	negative selection	6016021
39313089	39313112	21	-	27260156	CAL120	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.40423832586854774	[369]	[322,209,503]	-5	hSpCas9	negative selection	6080303
39312872	39312895	21	+	27260156	CAL120	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7952786757354988	[1024]	[2274,1943,2425]	9	hSpCas9	negative selection	6080304
39313267	39313290	21	+	27260156	CAL120	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.8847892727763813	[194]	[165,135,97]	-8	hSpCas9	negative selection	6080305
39313239	39313262	21	+	27260156	CADOES1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.01692792307546004	[366]	[515,309,259,259]	0	hSpCas9	negative selection	6137270
39313277	39313300	21	-	27260156	CADOES1	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.27611871285688183	[561]	[457,490,818,768]	4	hSpCas9	negative selection	6137271
39312882	39312905	21	-	27260156	CADOES1	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.03406579483645389	[244]	[190,189,163,349]	0	hSpCas9	negative selection	6137272
39313089	39313112	21	-	27260156	CADOES1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.039317067266191	[369]	[395,374,269,296]	0	hSpCas9	negative selection	6201554
39312872	39312895	21	+	27260156	CADOES1	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.5271736725700391	[1024]	[1323,1255,1263,1661]	8	hSpCas9	negative selection	6201555
39313267	39313290	21	+	27260156	CADOES1	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.5544208569554616	[194]	[146,107,137,99]	-7	hSpCas9	negative selection	6201556
39313239	39313262	21	+	27260156	EWS502	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.31377645482442823	[366]	[341,643,490,462]	5	hSpCas9	negative selection	6258521
39313277	39313300	21	-	27260156	EWS502	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.4388781266365628	[561]	[981,612,602,1025]	7	hSpCas9	negative selection	6258522
39312882	39312905	21	-	27260156	EWS502	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.5269562570453632	[244]	[308,467,231,495]	8	hSpCas9	negative selection	6258523
39313089	39313112	21	-	27260156	EWS502	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.467237355070574	[369]	[233,300,361,238]	-7	hSpCas9	negative selection	6322805
39312872	39312895	21	+	27260156	EWS502	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.6736969081305126	[1024]	[1451,1878,1703,1926]	9	hSpCas9	negative selection	6322806
39313267	39313290	21	+	27260156	EWS502	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.4797410888147109	[194]	[144,148,169,126]	-7	hSpCas9	negative selection	6322807
39313239	39313262	21	+	27260156	EW8	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.2871186765915191	[366]	[346,260,326,518]	5	hSpCas9	negative selection	6379772
39313277	39313300	21	-	27260156	EW8	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.1617359632282926	[561]	[717,456,464,426]	3	hSpCas9	negative selection	6379773
39312882	39312905	21	-	27260156	EW8	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.26735194022087394	[244]	[287,272,202,202]	5	hSpCas9	negative selection	6379774
39313089	39313112	21	-	27260156	EW8	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.4762536754338296	[369]	[178,233,218,224]	-7	hSpCas9	negative selection	6444056
39312872	39312895	21	+	27260156	EW8	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7499792183820639	[1024]	[2110,1304,1083,1215]	9	hSpCas9	negative selection	6444057
39313267	39313290	21	+	27260156	EW8	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.32001786017728695	[194]	[119,123,121,139]	-5	hSpCas9	negative selection	6444058
39313239	39313262	21	+	27260156	CORL105	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.12195211555731938	[366]	[304,405,522,361]	-2	hSpCas9	negative selection	6501023
39313277	39313300	21	-	27260156	CORL105	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.2210273545785641	[561]	[540,665,631,426]	-4	hSpCas9	negative selection	6501024
39312882	39312905	21	-	27260156	CORL105	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.21990806294440857	[244]	[344,304,421,278]	4	hSpCas9	negative selection	6501025
39313089	39313112	21	-	27260156	CORL105	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.5510345931524694	[369]	[291,272,378,251]	-7	hSpCas9	negative selection	6565307
39312872	39312895	21	+	27260156	CORL105	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.45858820941605427	[1024]	[1384,1785,1948,1510]	8	hSpCas9	negative selection	6565308
39313267	39313290	21	+	27260156	CORL105	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.5771506148913197	[194]	[183,87,232,121]	-8	hSpCas9	negative selection	6565309
39313239	39313262	21	+	27260156	HS294T	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.015870533408021748	[366]	[159,134,128,148]	0	hSpCas9	negative selection	6622274
39313277	39313300	21	-	27260156	HS294T	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.13268689893258143	[561]	[250,172,154,210]	-2	hSpCas9	negative selection	6622275
39312882	39312905	21	-	27260156	HS294T	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.0915856512328932	[244]	[55,118,95,85]	-1	hSpCas9	negative selection	6622276
39313089	39313112	21	-	27260156	HS294T	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.3175776764070534	[369]	[80,98,90,206]	-4	hSpCas9	negative selection	6686558
39312872	39312895	21	+	27260156	HS294T	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7568093623348573	[1024]	[519,609,593,1028]	8	hSpCas9	negative selection	6686559
39313267	39313290	21	+	27260156	HS294T	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.26000958532916574	[194]	[48,96,41,63]	-4	hSpCas9	negative selection	6686560
39313239	39313262	21	+	27260156	HCC44	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.2853773282060024	[366]	[253,261,528,349]	-4	hSpCas9	negative selection	6743525
39313277	39313300	21	-	27260156	HCC44	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.14068171042897004	[561]	[597,572,713,446]	-2	hSpCas9	negative selection	6743526
39312882	39312905	21	-	27260156	HCC44	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.012646431750269915	[244]	[224,341,265,266]	0	hSpCas9	negative selection	6743527
39313089	39313112	21	-	27260156	HCC44	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.35185816723076196	[369]	[399,239,327,358]	-5	hSpCas9	negative selection	6807809
39312872	39312895	21	+	27260156	HCC44	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.48528170990636066	[1024]	[1839,1219,2118,1466]	7	hSpCas9	negative selection	6807810
39313267	39313290	21	+	27260156	HCC44	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.3379810790771496	[194]	[112,122,251,221]	-5	hSpCas9	negative selection	6807811
39313239	39313262	21	+	27260156	G402	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.3250053107292725	[366]	[978,303,334,663]	4	hSpCas9	negative selection	6864776
39313277	39313300	21	-	27260156	G402	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.10217235634003818	[561]	[993,891,624,488]	1	hSpCas9	negative selection	6864777
39312882	39312905	21	-	27260156	G402	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.28762347440177094	[244]	[440,340,99,135]	-4	hSpCas9	negative selection	6864778
39313089	39313112	21	-	27260156	G402	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.7591366016454679	[369]	[194,225,550,89]	-7	hSpCas9	negative selection	6929060
39312872	39312895	21	+	27260156	G402	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.6477674965821831	[1024]	[2459,1857,1536,2037]	7	hSpCas9	negative selection	6929061
39313267	39313290	21	+	27260156	G402	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.7930268461918806	[194]	[400,198,292,724]	8	hSpCas9	negative selection	6929062
39313239	39313262	21	+	27260156	L33	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.2700430065664142	[366]	[493,166,228,501]	6	hSpCas9	negative selection	6986027
39313277	39313300	21	-	27260156	L33	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.39470121364437516	[561]	[936,197,469,781]	7	hSpCas9	negative selection	6986028
39312882	39312905	21	-	27260156	L33	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.39042805447441786	[244]	[265,167,118,418]	7	hSpCas9	negative selection	6986029
39313089	39313112	21	-	27260156	L33	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.2726113837133985	[369]	[228,137,181,370]	-6	hSpCas9	negative selection	7050311
39312872	39312895	21	+	27260156	L33	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.3906599348980526	[1024]	[1102,588,896,1412]	7	hSpCas9	negative selection	7050312
39313267	39313290	21	+	27260156	L33	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.15954298721907212	[194]	[146,118,144,204]	3	hSpCas9	negative selection	7050313
39313239	39313262	21	+	27260156	K562	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.0228047046109478	[366]	[300,358,281,373]	0	hSpCas9	negative selection	7107278
39313277	39313300	21	-	27260156	K562	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.12447473569686932	[561]	[375,491,523,433]	-1	hSpCas9	negative selection	7107279
39312882	39312905	21	-	27260156	K562	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.2662379139917932	[244]	[355,464,185,77]	3	hSpCas9	negative selection	7107280
39313089	39313112	21	-	27260156	K562	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.14508419545497747	[369]	[452,403,221,143]	-2	hSpCas9	negative selection	7171562
39312872	39312895	21	+	27260156	K562	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.5592969338218856	[1024]	[1535,1680,1033,1159]	7	hSpCas9	negative selection	7171563
39313267	39313290	21	+	27260156	K562	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.273020758832913	[194]	[225,136,65,148]	-3	hSpCas9	negative selection	7171564
39313239	39313262	21	+	27260156	HT29	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.15761681389491586	[366]	[592,644,424,360]	3	hSpCas9	negative selection	7228529
39313277	39313300	21	-	27260156	HT29	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.21051353407310008	[561]	[634,864,898,755]	4	hSpCas9	negative selection	7228530
39312882	39312905	21	-	27260156	HT29	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.13488803781372694	[244]	[460,310,308,243]	2	hSpCas9	negative selection	7228531
39313089	39313112	21	-	27260156	HT29	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.2932256497925842	[369]	[493,221,461,293]	-5	hSpCas9	negative selection	7292813
39312872	39312895	21	+	27260156	HT29	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.4859987108276498	[1024]	[1809,2127,1703,1405]	8	hSpCas9	negative selection	7292814
39313267	39313290	21	+	27260156	HT29	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.5744196740485357	[194]	[300,149,109,92]	-7	hSpCas9	negative selection	7292815
39313239	39313262	21	+	27260156	MHHES1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.3225028055603692	[366]	[681,575,370,463]	6	hSpCas9	negative selection	7349780
39313277	39313300	21	-	27260156	MHHES1	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.46735757187565197	[561]	[1125,1058,823,587]	8	hSpCas9	negative selection	7349781
39312882	39312905	21	-	27260156	MHHES1	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.5309104113703803	[244]	[533,409,486,215]	8	hSpCas9	negative selection	7349782
39313089	39313112	21	-	27260156	MHHES1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.38759252163540564	[369]	[395,270,254,342]	-6	hSpCas9	negative selection	7414064
39312872	39312895	21	+	27260156	MHHES1	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.4583563698673334	[1024]	[2067,1695,1335,1334]	7	hSpCas9	negative selection	7414065
39313267	39313290	21	+	27260156	MHHES1	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.6604443794586092	[194]	[111,235,133,88]	-8	hSpCas9	negative selection	7414066
39313239	39313262	21	+	27260156	MEWO	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.0732609797532961	[366]	[512,367,231]	1	hSpCas9	negative selection	7471031
39313277	39313300	21	-	27260156	MEWO	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.01316915246453032	[561]	[616,415,575]	0	hSpCas9	negative selection	7471032
39312882	39312905	21	-	27260156	MEWO	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.3449060185080446	[244]	[309,278,287]	7	hSpCas9	negative selection	7471033
39313089	39313112	21	-	27260156	MEWO	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.49500673177344007	[369]	[285,168,289]	-8	hSpCas9	negative selection	7535315
39312872	39312895	21	+	27260156	MEWO	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.3902979601140528	[1024]	[1215,1131,1414]	7	hSpCas9	negative selection	7535316
39313267	39313290	21	+	27260156	MEWO	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.5585846515831607	[194]	[140,101,131]	-8	hSpCas9	negative selection	7535317
39313239	39313262	21	+	27260156	LNCAPCLONEFGC	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.5463883545953128	[366]	[166,240,195,301]	-7	hSpCas9	negative selection	7592282
39313277	39313300	21	-	27260156	LNCAPCLONEFGC	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.3737221663225455	[561]	[427,352,511,297]	-5	hSpCas9	negative selection	7592283
39312882	39312905	21	-	27260156	LNCAPCLONEFGC	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.22521661774879553	[244]	[161,206,238,157]	-4	hSpCas9	negative selection	7592284
39313089	39313112	21	-	27260156	LNCAPCLONEFGC	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.5584942876593944	[369]	[195,231,230,251]	-7	hSpCas9	negative selection	7656566
39312872	39312895	21	+	27260156	LNCAPCLONEFGC	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.32310716315173105	[1024]	[932,1053,1369,1330]	5	hSpCas9	negative selection	7656567
39313267	39313290	21	+	27260156	LNCAPCLONEFGC	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.9839354494278194	[194]	[123,57,44,124]	-8	hSpCas9	negative selection	7656568
39313239	39313262	21	+	27260156	PANC0327	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.24786150923225506	[366]	[282,394,495,364]	3	hSpCas9	negative selection	7713533
39313277	39313300	21	-	27260156	PANC0327	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.3406914956618815	[561]	[814,331,521,912]	5	hSpCas9	negative selection	7713534
39312882	39312905	21	-	27260156	PANC0327	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.38992876426364664	[244]	[314,176,72,109]	-5	hSpCas9	negative selection	7713535
39313089	39313112	21	-	27260156	PANC0327	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.1651312313347844	[369]	[270,358,234,296]	-2	hSpCas9	negative selection	7777817
39312872	39312895	21	+	27260156	PANC0327	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.6095282557096424	[1024]	[1573,1278,1428,1303]	8	hSpCas9	negative selection	7777818
39313267	39313290	21	+	27260156	PANC0327	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.25732145139351914	[194]	[90,170,209,99]	-4	hSpCas9	negative selection	7777819
39313239	39313262	21	+	27260156	NCIH2009	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.06307276997542738	[366]	[751,472,424]	0	hSpCas9	negative selection	7834784
39313277	39313300	21	-	27260156	NCIH2009	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.3599422326275653	[561]	[1225,652,1191]	5	hSpCas9	negative selection	7834785
39312882	39312905	21	-	27260156	NCIH2009	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.4167195808847701	[244]	[243,222,299]	-5	hSpCas9	negative selection	7834786
39313089	39313112	21	-	27260156	NCIH2009	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-1.1622874508833243	[369]	[373,219,126]	-8	hSpCas9	negative selection	7899068
39312872	39312895	21	+	27260156	NCIH2009	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.49333212954871253	[1024]	[2585,1743,1831]	6	hSpCas9	negative selection	7899069
39313267	39313290	21	+	27260156	NCIH2009	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-1.1251400391357136	[194]	[136,118,120]	-8	hSpCas9	negative selection	7899070
39313239	39313262	21	+	27260156	NCIH1373	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.24486706075122033	[366]	[406,505,646,94]	2	hSpCas9	negative selection	7956035
39313277	39313300	21	-	27260156	NCIH1373	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.26381075152745503	[561]	[907,696,574,231]	2	hSpCas9	negative selection	7956036
39312882	39312905	21	-	27260156	NCIH1373	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	-0.03936863900792442	[244]	[494,186,196,60]	0	hSpCas9	negative selection	7956037
39313089	39313112	21	-	27260156	NCIH1373	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.6508915488438911	[369]	[352,244,256,55]	-6	hSpCas9	negative selection	8020319
39312872	39312895	21	+	27260156	NCIH1373	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.6853577607016654	[1024]	[2124,1280,1668,643]	6	hSpCas9	negative selection	8020320
39313267	39313290	21	+	27260156	NCIH1373	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.9700772395260662	[194]	[130,25,237,14]	-7	hSpCas9	negative selection	8020321
39313239	39313262	21	+	27260156	PATU8902	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.3517692029136581	[366]	[509,523,715,863]	3	hSpCas9	negative selection	8077286
39313277	39313300	21	-	27260156	PATU8902	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.49532721655484035	[561]	[850,1439,937,1238]	5	hSpCas9	negative selection	8077287
39312882	39312905	21	-	27260156	PATU8902	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.47041693199954276	[244]	[576,280,389,683]	5	hSpCas9	negative selection	8077288
39313089	39313112	21	-	27260156	PATU8902	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.30002456232551333	[369]	[370,829,765,521]	3	hSpCas9	negative selection	8141570
39312872	39312895	21	+	27260156	PATU8902	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7200317533048013	[1024]	[2574,2728,1570,2761]	7	hSpCas9	negative selection	8141571
39313267	39313290	21	+	27260156	PATU8902	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.07589433683860958	[194]	[331,110,376,164]	0	hSpCas9	negative selection	8141572
39313239	39313262	21	+	27260156	PANC1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.2904506968699326	[366]	[294,375,397,454]	5	hSpCas9	negative selection	8198537
39313277	39313300	21	-	27260156	PANC1	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.08677497008397134	[561]	[433,727,517,422]	1	hSpCas9	negative selection	8198538
39312882	39312905	21	-	27260156	PANC1	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.26086353347809654	[244]	[279,350,198,201]	4	hSpCas9	negative selection	8198539
39313089	39313112	21	-	27260156	PANC1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.02789061129464787	[369]	[296,359,287,348]	0	hSpCas9	negative selection	8262821
39312872	39312895	21	+	27260156	PANC1	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.506293087541994	[1024]	[1149,1547,1233,1131]	7	hSpCas9	negative selection	8262822
39313267	39313290	21	+	27260156	PANC1	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.04674597372152123	[194]	[315,182,115,86]	0	hSpCas9	negative selection	8262823
39313239	39313262	21	+	27260156	PANC0813	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.10228701736411594	[366]	[508,416,643,294]	1	hSpCas9	negative selection	8319788
39313277	39313300	21	-	27260156	PANC0813	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.0899409503821832	[561]	[981,757,689,420]	1	hSpCas9	negative selection	8319789
39312882	39312905	21	-	27260156	PANC0813	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.13280038524117044	[244]	[284,359,234,374]	2	hSpCas9	negative selection	8319790
39313089	39313112	21	-	27260156	PANC0813	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.39940261464083143	[369]	[319,367,170,449]	-6	hSpCas9	negative selection	8384072
39312872	39312895	21	+	27260156	PANC0813	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.3231688785792046	[1024]	[1909,1278,1475,1400]	5	hSpCas9	negative selection	8384073
39313267	39313290	21	+	27260156	PANC0813	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.8510760744571557	[194]	[254,63,101,99]	-8	hSpCas9	negative selection	8384074
39313239	39313262	21	+	27260156	RDES	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.058531358059632665	[366]	[401,294,370,575]	-1	hSpCas9	negative selection	8441039
39313277	39313300	21	-	27260156	RDES	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.1071327354483318	[561]	[551,644,856,761]	1	hSpCas9	negative selection	8441040
39312882	39312905	21	-	27260156	RDES	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.2035697279975246	[244]	[297,313,322,364]	3	hSpCas9	negative selection	8441041
39313089	39313112	21	-	27260156	RDES	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.2499833193483882	[369]	[314,380,395,331]	-4	hSpCas9	negative selection	8505323
39312872	39312895	21	+	27260156	RDES	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.6603219006722825	[1024]	[1345,1846,2155,2229]	9	hSpCas9	negative selection	8505324
39313267	39313290	21	+	27260156	RDES	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.4894170230563004	[194]	[182,110,176,162]	-7	hSpCas9	negative selection	8505325
39313239	39313262	21	+	27260156	PC3	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.24213006832248318	[366]	[235,521,649,450]	5	hSpCas9	negative selection	8562290
39313277	39313300	21	-	27260156	PC3	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.51487526102072	[561]	[638,778,1194,712]	9	hSpCas9	negative selection	8562291
39312882	39312905	21	-	27260156	PC3	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.4367460399491243	[244]	[149,515,538,236]	8	hSpCas9	negative selection	8562292
39313089	39313112	21	-	27260156	PC3	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.4596383675404941	[369]	[202,264,487,196]	-8	hSpCas9	negative selection	8626574
39312872	39312895	21	+	27260156	PC3	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.38274665490603366	[1024]	[875,1530,2256,1063]	7	hSpCas9	negative selection	8626575
39313267	39313290	21	+	27260156	PC3	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.2113411779426404	[194]	[74,140,303,237]	-5	hSpCas9	negative selection	8626576
39313239	39313262	21	+	27260156	PATU8988T	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.020282012539521332	[366]	[173,371,332,536]	0	hSpCas9	negative selection	8683541
39313277	39313300	21	-	27260156	PATU8988T	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	-0.10208991978719484	[561]	[549,481,569,410]	-2	hSpCas9	negative selection	8683542
39312882	39312905	21	-	27260156	PATU8988T	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.5346814709907559	[244]	[225,329,359,463]	8	hSpCas9	negative selection	8683543
39313089	39313112	21	-	27260156	PATU8988T	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.30451493233342003	[369]	[192,322,238,416]	-5	hSpCas9	negative selection	8747825
39312872	39312895	21	+	27260156	PATU8988T	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7928019599428782	[1024]	[1515,2097,1737,1531]	9	hSpCas9	negative selection	8747826
39313267	39313290	21	+	27260156	PATU8988T	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	0.03230005382097789	[194]	[147,339,170,119]	0	hSpCas9	negative selection	8747827
39313239	39313262	21	+	27260156	T47D	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.12493134184081589	[366]	[455,447,430,533]	2	hSpCas9	negative selection	8804792
39313277	39313300	21	-	27260156	T47D	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.03950142431168524	[561]	[692,572,734,698]	0	hSpCas9	negative selection	8804793
39312882	39312905	21	-	27260156	T47D	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.16913592995585636	[244]	[336,339,295,308]	3	hSpCas9	negative selection	8804794
39313089	39313112	21	-	27260156	T47D	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.24390217862114466	[369]	[378,378,375,318]	-5	hSpCas9	negative selection	8869076
39312872	39312895	21	+	27260156	T47D	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.5527955055043272	[1024]	[1822,1601,1800,1793]	9	hSpCas9	negative selection	8869077
39313267	39313290	21	+	27260156	T47D	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.2769272403479133	[194]	[149,219,166,210]	-6	hSpCas9	negative selection	8869078
39313239	39313262	21	+	27260156	SU8686	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.02793494993145218	[366]	[279,320,433,482]	0	hSpCas9	negative selection	8926043
39313277	39313300	21	-	27260156	SU8686	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.5572917258345483	[561]	[543,632,943,1287]	8	hSpCas9	negative selection	8926044
39312882	39312905	21	-	27260156	SU8686	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.15774205090591786	[244]	[240,250,272,332]	2	hSpCas9	negative selection	8926045
39313089	39313112	21	-	27260156	SU8686	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.3500942028857002	[369]	[299,249,192,429]	-5	hSpCas9	negative selection	8990327
39312872	39312895	21	+	27260156	SU8686	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.5032655239973103	[1024]	[1171,1370,1724,1547]	8	hSpCas9	negative selection	8990328
39313267	39313290	21	+	27260156	SU8686	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.30461930542333393	[194]	[144,154,187,135]	-5	hSpCas9	negative selection	8990329
39313239	39313262	21	+	27260156	SKES1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.009099066588126925	[366]	[405,436,392,259]	0	hSpCas9	negative selection	9047294
39313277	39313300	21	-	27260156	SKES1	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.29460798559476264	[561]	[650,692,670,719]	6	hSpCas9	negative selection	9047295
39312882	39312905	21	-	27260156	SKES1	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.15074313300080056	[244]	[427,322,144,221]	3	hSpCas9	negative selection	9047296
39313089	39313112	21	-	27260156	SKES1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.6853171588122773	[369]	[197,307,244,175]	-9	hSpCas9	negative selection	9111578
39312872	39312895	21	+	27260156	SKES1	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.598182124491671	[1024]	[2016,1726,1391,1172]	9	hSpCas9	negative selection	9111579
39313267	39313290	21	+	27260156	SKES1	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.37605677452042086	[194]	[113,227,132,129]	-7	hSpCas9	negative selection	9111580
39313239	39313262	21	+	27260156	TOV112D	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.008585998078711188	[366]	[301,503,400,284]	0	hSpCas9	negative selection	9168545
39313277	39313300	21	-	27260156	TOV112D	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.4032796369142838	[561]	[480,944,558,1010]	7	hSpCas9	negative selection	9168546
39312882	39312905	21	-	27260156	TOV112D	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.6253991037648349	[244]	[428,445,412,249]	9	hSpCas9	negative selection	9168547
39313089	39313112	21	-	27260156	TOV112D	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.2357519434587126	[369]	[230,174,391,415]	-4	hSpCas9	negative selection	9232829
39312872	39312895	21	+	27260156	TOV112D	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.7482597455296545	[1024]	[1715,1659,1839,1663]	9	hSpCas9	negative selection	9232830
39313267	39313290	21	+	27260156	TOV112D	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.661581862464929	[194]	[125,173,143,63]	-8	hSpCas9	negative selection	9232831
39313239	39313262	21	+	27260156	TC71	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.2827917889798948	[366]	[458,399,460,602]	7	hSpCas9	negative selection	9289796
39313277	39313300	21	-	27260156	TC71	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.21968151068648017	[561]	[687,728,625,769]	5	hSpCas9	negative selection	9289797
39312882	39312905	21	-	27260156	TC71	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.11144241514371267	[244]	[351,245,245,290]	3	hSpCas9	negative selection	9289798
39313089	39313112	21	-	27260156	TC71	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.1622385798969676	[369]	[362,337,274,449]	-4	hSpCas9	negative selection	9354080
39312872	39312895	21	+	27260156	TC71	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.4904155977171367	[1024]	[1589,1559,1422,1607]	9	hSpCas9	negative selection	9354081
39313267	39313290	21	+	27260156	TC71	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.32401582431087683	[194]	[202,195,134,131]	-7	hSpCas9	negative selection	9354082
39313239	39313262	21	+	27260156	TC32	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.3856196382197857	[366]	[481,342,513,484]	6	hSpCas9	negative selection	9411047
39313277	39313300	21	-	27260156	TC32	viability	AGCTGTACTTCCTTATCGCCCGG	BRWD1	ENSG00000185658	0.4259353542774743	[561]	[660,532,974,747]	7	hSpCas9	negative selection	9411048
39312882	39312905	21	-	27260156	TC32	viability	CCAGTTGTTGCCGAAGAGATTGG	BRWD1	ENSG00000185658	0.6355706123937979	[244]	[400,257,342,440]	9	hSpCas9	negative selection	9411049
39313089	39313112	21	-	27260156	TC32	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.045150446714587456	[369]	[298,188,511,425]	-1	hSpCas9	negative selection	9475331
39312872	39312895	21	+	27260156	TC32	viability	CCCTCCCAGTCCAATCTCTTCGG	BRWD1	ENSG00000185658	0.5489659721785229	[1024]	[1186,820,2303,1669]	8	hSpCas9	negative selection	9475332
39313267	39313290	21	+	27260156	TC32	viability	CCGATAGGTACCGGGCGATAAGG	BRWD1	ENSG00000185658	-0.40456706351205307	[194]	[133,139,169,103]	-6	hSpCas9	negative selection	9475333
39255776	39255799	21	+	27869803	HPAFII	viability after 27 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.6155090933085033	[425]	[77,202,NaN]	-4	hSpCas9	negative selection	9579258
39270414	39270437	21	-	27869803	HPAFII	viability after 27 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	1.1046048482013526	[171]	[128,248,NaN]	8	hSpCas9	negative selection	9579259
39278757	39278780	21	+	27869803	HPAFII	viability after 27 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.566735055460456	[75]	[86,35,NaN]	4	hSpCas9	negative selection	9579260
39280186	39280209	21	+	27869803	HPAFII	viability after 27 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.8146528062216066	[226]	[294,138,NaN]	6	hSpCas9	negative selection	9579261
39313442	39313465	21	+	27869803	HPAFII	viability after 27 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.7217062683294821	[368]	[78,41,NaN]	-8	hSpCas9	negative selection	9579262
39255776	39255799	21	+	27869803	HPAFII	viability after 15 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.5227422697594225	[425]	[404,264,NaN]	-5	hSpCas9	negative selection	9661707
39270414	39270437	21	-	27869803	HPAFII	viability after 15 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.6797739501258855	[171]	[276,307,NaN]	7	hSpCas9	negative selection	9661708
39278757	39278780	21	+	27869803	HPAFII	viability after 15 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.5171769910029724	[75]	[246,35,NaN]	6	hSpCas9	negative selection	9661709
39280186	39280209	21	+	27869803	HPAFII	viability after 15 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.8743664576783062	[226]	[638,327,NaN]	8	hSpCas9	negative selection	9661710
39313442	39313465	21	+	27869803	HPAFII	viability after 15 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.3506477363758303	[368]	[384,264,NaN]	-4	hSpCas9	negative selection	9661711
39255776	39255799	21	+	27869803	ASPC1	viability after 36 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.04488232540862347	[1335]	[487,193,626]	0	hSpCas9	negative selection	9744156
39270414	39270437	21	-	27869803	ASPC1	viability after 36 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.641027707657047	[482]	[93,78,139]	-6	hSpCas9	negative selection	9744157
39278757	39278780	21	+	27869803	ASPC1	viability after 36 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.8939405002251657	[248]	[69,187,202]	8	hSpCas9	negative selection	9744158
39280186	39280209	21	+	27869803	ASPC1	viability after 36 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	-0.4514777562291296	[665]	[60,248,181]	-4	hSpCas9	negative selection	9744159
39313442	39313465	21	+	27869803	ASPC1	viability after 36 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.9355095327772323	[712]	[259,870,308]	8	hSpCas9	negative selection	9744160
39255776	39255799	21	+	27869803	PATU8988S	viability after 35 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.18247797169402036	[1091]	[543,453,NaN]	2	hSpCas9	negative selection	9826605
39270414	39270437	21	-	27869803	PATU8988S	viability after 35 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	-0.4122947652056084	[407]	[112,133,NaN]	-4	hSpCas9	negative selection	9826606
39278757	39278780	21	+	27869803	PATU8988S	viability after 35 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.6553607182225545	[251]	[37,90,NaN]	-6	hSpCas9	negative selection	9826607
39280186	39280209	21	+	27869803	PATU8988S	viability after 35 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.266971280798636	[524]	[221,286,NaN]	3	hSpCas9	negative selection	9826608
39313442	39313465	21	+	27869803	PATU8988S	viability after 35 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.020456300188994303	[631]	[230,270,NaN]	0	hSpCas9	negative selection	9826609
39255776	39255799	21	+	27869803	PATU8988S	viability after 31 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	0.32722792491400643	[1091]	[584,496,NaN]	4	hSpCas9	negative selection	9909054
39270414	39270437	21	-	27869803	PATU8988S	viability after 31 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.1385154154425855	[407]	[186,168,NaN]	1	hSpCas9	negative selection	9909055
39278757	39278780	21	+	27869803	PATU8988S	viability after 31 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	-0.15903233571475517	[251]	[67,117,NaN]	-2	hSpCas9	negative selection	9909056
39280186	39280209	21	+	27869803	PATU8988S	viability after 31 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.06600649602388023	[524]	[124,338,NaN]	0	hSpCas9	negative selection	9909057
39313442	39313465	21	+	27869803	PATU8988S	viability after 31 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	0.4216482132163298	[631]	[293,392,NaN]	5	hSpCas9	negative selection	9909058
39255776	39255799	21	+	27869803	HPAFII	viability after 35 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.7602592370591047	[425]	[68,192,NaN]	-4	hSpCas9	negative selection	9991503
39270414	39270437	21	-	27869803	HPAFII	viability after 35 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	0.8896774072027391	[171]	[110,217,NaN]	6	hSpCas9	negative selection	9991504
39278757	39278780	21	+	27869803	HPAFII	viability after 35 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	0.7905149477361287	[75]	[106,20,NaN]	5	hSpCas9	negative selection	9991505
39280186	39280209	21	+	27869803	HPAFII	viability after 35 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.6195005302910057	[226]	[105,255,NaN]	4	hSpCas9	negative selection	9991506
39313442	39313465	21	+	27869803	HPAFII	viability after 35 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-0.8414438560876437	[368]	[139,63,NaN]	-5	hSpCas9	negative selection	9991507
39255776	39255799	21	+	27869803	HPAFII	viability after 31 days	ACGCAGACCAATATTTGGAGGGG	BRWD1	ENSG00000185658	-0.8441976399566028	[425]	[69,201,NaN]	-5	hSpCas9	negative selection	10073952
39270414	39270437	21	-	27869803	HPAFII	viability after 31 days	TAGGGACTTATCTTCCGAAGAGG	BRWD1	ENSG00000185658	1.3930296811814409	[171]	[197,313,NaN]	8	hSpCas9	negative selection	10073953
39278757	39278780	21	+	27869803	HPAFII	viability after 31 days	GAACAAAGCATTTGAACGCCTGG	BRWD1	ENSG00000185658	1.0842644060562336	[75]	[155,18,NaN]	7	hSpCas9	negative selection	10073954
39280186	39280209	21	+	27869803	HPAFII	viability after 31 days	AACTGTCCCATCAGCACCAGTGG	BRWD1	ENSG00000185658	0.7633790349084298	[226]	[232,197,NaN]	5	hSpCas9	negative selection	10073955
39313442	39313465	21	+	27869803	HPAFII	viability after 31 days	CCCGACTCGATGAGAGGCACCGG	BRWD1	ENSG00000185658	-1.253889186964829	[368]	[71,102,NaN]	-6	hSpCas9	negative selection	10073956
39312876	39312899	21	-	28162770	P31FUJ	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.4372024194301441	[268]	[427]	5	hSpCas9	negative selection	10119303
39202426	39202449	21	-	28162770	P31FUJ	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.2488495790644818	[327]	[457]	2	hSpCas9	negative selection	10119304
39312840	39312863	21	-	28162770	P31FUJ	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.8162586140365076	[158]	[328]	8	hSpCas9	negative selection	10119305
39313436	39313459	21	+	28162770	P31FUJ	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.6197375266599523	[457]	[826]	7	hSpCas9	negative selection	10119306
39313071	39313094	21	-	28162770	P31FUJ	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.3647603330864112	[303]	[459]	4	hSpCas9	negative selection	10119307
39313449	39313472	21	+	28162770	P31FUJ	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.3990051597664451	[201]	[312]	4	hSpCas9	negative selection	10119308
39313239	39313262	21	+	28162770	P31FUJ	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.7259358303993664	[265]	[516]	8	hSpCas9	negative selection	10119309
39298513	39298536	21	-	28162770	P31FUJ	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.25946362115309585	[931]	[1310]	3	hSpCas9	negative selection	10119310
39313089	39313112	21	-	28162770	P31FUJ	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.452465202102463	[124]	[401]	9	hSpCas9	negative selection	10119311
39258486	39258509	21	-	28162770	P31FUJ	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.3165363865760562	[286]	[419]	3	hSpCas9	negative selection	10119312
39312876	39312899	21	-	28162770	TF1	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10288669
39202426	39202449	21	-	28162770	TF1	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10288670
39312840	39312863	21	-	28162770	TF1	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10288671
39313436	39313459	21	+	28162770	TF1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	NaN	[NaN]	[269]	1	hSpCas9	negative selection	10288672
39313071	39313094	21	-	28162770	TF1	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10288673
39313449	39313472	21	+	28162770	TF1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10288674
39313239	39313262	21	+	28162770	TF1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10288675
39298513	39298536	21	-	28162770	TF1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	NaN	[NaN]	[239]	1	hSpCas9	negative selection	10288676
39313089	39313112	21	-	28162770	TF1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10288677
39258486	39258509	21	-	28162770	TF1	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10288678
39312876	39312899	21	-	28162770	SKM1	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.20574329246089873	[102]	[209]	2	hSpCas9	negative selection	10458035
39202426	39202449	21	-	28162770	SKM1	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.27928163781517606	[54]	[117]	2	hSpCas9	negative selection	10458036
39312840	39312863	21	-	28162770	SKM1	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.7214415332608839	[46]	[136]	7	hSpCas9	negative selection	10458037
39313436	39313459	21	+	28162770	SKM1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.5176283985988155	[161]	[409]	5	hSpCas9	negative selection	10458038
39313071	39313094	21	-	28162770	SKM1	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.19685732922931037	[75]	[153]	2	hSpCas9	negative selection	10458039
39313449	39313472	21	+	28162770	SKM1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.5621417933110546	[58]	[153]	5	hSpCas9	negative selection	10458040
39313239	39313262	21	+	28162770	SKM1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.22239242133644793	[63]	[131]	2	hSpCas9	negative selection	10458041
39298513	39298536	21	-	28162770	SKM1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.19017301592409686	[176]	[356]	1	hSpCas9	negative selection	10458042
39313089	39313112	21	-	28162770	SKM1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10458043
39258486	39258509	21	-	28162770	SKM1	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.15563048894953996	[64]	[127]	1	hSpCas9	negative selection	10458044
39312876	39312899	21	-	28162770	SKM1	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.20574329246089873	[102]	[209]	2	hSpCas9	negative selection	10627401
39202426	39202449	21	-	28162770	SKM1	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.27928163781517606	[54]	[117]	2	hSpCas9	negative selection	10627402
39312840	39312863	21	-	28162770	SKM1	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.7214415332608839	[46]	[136]	7	hSpCas9	negative selection	10627403
39313436	39313459	21	+	28162770	SKM1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.5176283985988155	[161]	[409]	5	hSpCas9	negative selection	10627404
39313071	39313094	21	-	28162770	SKM1	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.19685732922931037	[75]	[153]	2	hSpCas9	negative selection	10627405
39313449	39313472	21	+	28162770	SKM1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.5621417933110546	[58]	[153]	5	hSpCas9	negative selection	10627406
39313239	39313262	21	+	28162770	SKM1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.22239242133644793	[63]	[131]	2	hSpCas9	negative selection	10627407
39298513	39298536	21	-	28162770	SKM1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.19017301592409686	[176]	[356]	1	hSpCas9	negative selection	10627408
39313089	39313112	21	-	28162770	SKM1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10627409
39258486	39258509	21	-	28162770	SKM1	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.15563048894953996	[64]	[127]	1	hSpCas9	negative selection	10627410
39312876	39312899	21	-	28162770	PL21	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.6740708028217325	[323]	[224]	6	hSpCas9	negative selection	10796767
39202426	39202449	21	-	28162770	PL21	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.2922578164777514	[181]	[96]	2	hSpCas9	negative selection	10796768
39312840	39312863	21	-	28162770	PL21	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.7334399953879834	[198]	[143]	6	hSpCas9	negative selection	10796769
39313436	39313459	21	+	28162770	PL21	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.7998386584673738	[486]	[368]	6	hSpCas9	negative selection	10796770
39313071	39313094	21	-	28162770	PL21	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	-0.3271073883755488	[293]	[101]	-2	hSpCas9	negative selection	10796771
39313449	39313472	21	+	28162770	PL21	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	1.1746045223821824	[170]	[167]	8	hSpCas9	negative selection	10796772
39313239	39313262	21	+	28162770	PL21	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	1.2498926496864198	[170]	[176]	8	hSpCas9	negative selection	10796773
39298513	39298536	21	-	28162770	PL21	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	1.0231504344771716	[562]	[497]	8	hSpCas9	negative selection	10796774
39313089	39313112	21	-	28162770	PL21	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.467423493324472	[112]	[135]	9	hSpCas9	negative selection	10796775
39258486	39258509	21	-	28162770	PL21	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	1.2088568315904291	[164]	[165]	8	hSpCas9	negative selection	10796776
39312876	39312899	21	-	28162770	P31FUJ	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.4372024194301441	[268]	[427]	5	hSpCas9	negative selection	10966133
39202426	39202449	21	-	28162770	P31FUJ	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.2488495790644818	[327]	[457]	2	hSpCas9	negative selection	10966134
39312840	39312863	21	-	28162770	P31FUJ	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.8162586140365076	[158]	[328]	8	hSpCas9	negative selection	10966135
39313436	39313459	21	+	28162770	P31FUJ	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.6197375266599523	[457]	[826]	7	hSpCas9	negative selection	10966136
39313071	39313094	21	-	28162770	P31FUJ	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.3647603330864112	[303]	[459]	4	hSpCas9	negative selection	10966137
39313449	39313472	21	+	28162770	P31FUJ	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.3990051597664451	[201]	[312]	4	hSpCas9	negative selection	10966138
39313239	39313262	21	+	28162770	P31FUJ	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.7259358303993664	[265]	[516]	8	hSpCas9	negative selection	10966139
39298513	39298536	21	-	28162770	P31FUJ	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.25946362115309585	[931]	[1310]	3	hSpCas9	negative selection	10966140
39313089	39313112	21	-	28162770	P31FUJ	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.452465202102463	[124]	[401]	9	hSpCas9	negative selection	10966141
39258486	39258509	21	-	28162770	P31FUJ	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.3165363865760562	[286]	[419]	3	hSpCas9	negative selection	10966142
39312876	39312899	21	-	28162770	OCIAML5	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.5390450891693664	[113]	[298]	5	hSpCas9	negative selection	11135499
39202426	39202449	21	-	28162770	OCIAML5	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.27969201730688087	[182]	[400]	2	hSpCas9	negative selection	11135500
39312840	39312863	21	-	28162770	OCIAML5	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	-0.14635191068223063	[83]	[136]	-1	hSpCas9	negative selection	11135501
39313436	39313459	21	+	28162770	OCIAML5	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	-0.3763780438003961	[360]	[501]	-3	hSpCas9	negative selection	11135502
39313071	39313094	21	-	28162770	OCIAML5	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	-0.8019430914381606	[197]	[204]	-5	hSpCas9	negative selection	11135503
39313449	39313472	21	+	28162770	OCIAML5	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	-0.015565303146876208	[69]	[124]	0	hSpCas9	negative selection	11135504
39313239	39313262	21	+	28162770	OCIAML5	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.494952504986196	[113]	[289]	4	hSpCas9	negative selection	11135505
39298513	39298536	21	-	28162770	OCIAML5	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.4377071891256705	[531]	[708]	-3	hSpCas9	negative selection	11135506
39313089	39313112	21	-	28162770	OCIAML5	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.45351719437372223	[153]	[202]	-3	hSpCas9	negative selection	11135507
39258486	39258509	21	-	28162770	OCIAML5	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.37130488936231665	[176]	[246]	-3	hSpCas9	negative selection	11135508
39312876	39312899	21	-	28162770	EOL1	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	-0.4967487181799918	[615]	[229]	-4	hSpCas9	negative selection	11304865
39202426	39202449	21	-	28162770	EOL1	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-0.031209390467982642	[288]	[148]	0	hSpCas9	negative selection	11304866
39312840	39312863	21	-	28162770	EOL1	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	-0.11826531196843856	[341]	[165]	-1	hSpCas9	negative selection	11304867
39313436	39313459	21	+	28162770	EOL1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.5929417627808182	[1046]	[831]	5	hSpCas9	negative selection	11304868
39313071	39313094	21	-	28162770	EOL1	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	-0.047546231859580845	[511]	[260]	0	hSpCas9	negative selection	11304869
39313449	39313472	21	+	28162770	EOL1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.7631372248697865	[358]	[320]	6	hSpCas9	negative selection	11304870
39313239	39313262	21	+	28162770	EOL1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.12484642205636577	[281]	[161]	1	hSpCas9	negative selection	11304871
39298513	39298536	21	-	28162770	EOL1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.4558723086896175	[821]	[593]	4	hSpCas9	negative selection	11304872
39313089	39313112	21	-	28162770	EOL1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.6026196766831724	[154]	[123]	5	hSpCas9	negative selection	11304873
39258486	39258509	21	-	28162770	EOL1	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.2528484793029131	[241]	[106]	-2	hSpCas9	negative selection	11304874
39312876	39312899	21	-	28162770	MOLM13	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.8432567353934017	[423]	[549]	6	hSpCas9	negative selection	11474231
39202426	39202449	21	-	28162770	MOLM13	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-0.28531685362883835	[267]	[158]	-2	hSpCas9	negative selection	11474232
39312840	39312863	21	-	28162770	MOLM13	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	1.047355894510883	[262]	[392]	7	hSpCas9	negative selection	11474233
39313436	39313459	21	+	28162770	MOLM13	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	1.164597003786441	[922]	[1495]	8	hSpCas9	negative selection	11474234
39313071	39313094	21	-	28162770	MOLM13	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.7650215645848009	[445]	[547]	6	hSpCas9	negative selection	11474235
39313449	39313472	21	+	28162770	MOLM13	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.5503515417365517	[322]	[341]	4	hSpCas9	negative selection	11474236
39313239	39313262	21	+	28162770	MOLM13	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-1.1725682317682808	[317]	[101]	-6	hSpCas9	negative selection	11474237
39298513	39298536	21	-	28162770	MOLM13	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.3420739722847874	[921]	[844]	2	hSpCas9	negative selection	11474238
39313089	39313112	21	-	28162770	MOLM13	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.7349275014551082	[121]	[52]	-4	hSpCas9	negative selection	11474239
39258486	39258509	21	-	28162770	MOLM13	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.8443885433090643	[297]	[119]	-5	hSpCas9	negative selection	11474240
39312876	39312899	21	-	28162770	HEL	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	-0.8426879951698848	[405]	[144]	-5	hSpCas9	negative selection	11643597
39202426	39202449	21	-	28162770	HEL	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-1.7978337593856244	[265]	[48]	-7	hSpCas9	negative selection	11643598
39312840	39312863	21	-	28162770	HEL	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	-0.16046046056593594	[259]	[148]	-1	hSpCas9	negative selection	11643599
39313436	39313459	21	+	28162770	HEL	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.16615249232399254	[845]	[607]	1	hSpCas9	negative selection	11643600
39313071	39313094	21	-	28162770	HEL	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	-0.5695647717125072	[379]	[163]	-4	hSpCas9	negative selection	11643601
39313449	39313472	21	+	28162770	HEL	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.6427388320003569	[276]	[276]	5	hSpCas9	negative selection	11643602
39313239	39313262	21	+	28162770	HEL	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.37180947656879826	[298]	[147]	-3	hSpCas9	negative selection	11643603
39298513	39298536	21	-	28162770	HEL	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	-0.6527170515258145	[674]	[274]	-4	hSpCas9	negative selection	11643604
39313089	39313112	21	-	28162770	HEL	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	-0.8647449160430819	[144]	[50]	-5	hSpCas9	negative selection	11643605
39258486	39258509	21	-	28162770	HEL	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-2.6281150782927365	[221]	[22]	-8	hSpCas9	negative selection	11643606
39312876	39312899	21	-	28162770	MV411	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.5770395735555588	[299]	[376]	5	hSpCas9	negative selection	11812963
39202426	39202449	21	-	28162770	MV411	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-0.556297055596132	[198]	[113]	-4	hSpCas9	negative selection	11812964
39312840	39312863	21	-	28162770	MV411	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	1.3842162842432189	[180]	[397]	9	hSpCas9	negative selection	11812965
39313436	39313459	21	+	28162770	MV411	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.44060983320422964	[683]	[781]	4	hSpCas9	negative selection	11812966
39313071	39313094	21	-	28162770	MV411	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.8891226415158727	[265]	[414]	7	hSpCas9	negative selection	11812967
39313449	39313472	21	+	28162770	MV411	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.22753799334507036	[218]	[215]	2	hSpCas9	negative selection	11812968
39313239	39313262	21	+	28162770	MV411	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.9323414893778381	[157]	[253]	8	hSpCas9	negative selection	11812969
39298513	39298536	21	-	28162770	MV411	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.8477752773908471	[559]	[848]	7	hSpCas9	negative selection	11812970
39313089	39313112	21	-	28162770	MV411	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.0344438274485768	[152]	[263]	8	hSpCas9	negative selection	11812971
39258486	39258509	21	-	28162770	MV411	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	0.6865491850404768	[207]	[281]	6	hSpCas9	negative selection	11812972
39312876	39312899	21	-	28162770	MONOMAC1	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.2779528116364709	[217]	[302]	3	hSpCas9	negative selection	11982329
39202426	39202449	21	-	28162770	MONOMAC1	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	3.4040196297819034	[103]	[1261]	9	hSpCas9	negative selection	11982330
39312840	39312863	21	-	28162770	MONOMAC1	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.5987301007228383	[124]	[216]	6	hSpCas9	negative selection	11982331
39313436	39313459	21	+	28162770	MONOMAC1	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.12958294315253038	[306]	[384]	1	hSpCas9	negative selection	11982332
39313071	39313094	21	-	28162770	MONOMAC1	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.6500385040243364	[173]	[312]	6	hSpCas9	negative selection	11982333
39313449	39313472	21	+	28162770	MONOMAC1	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	1.3225994057836588	[127]	[366]	9	hSpCas9	negative selection	11982334
39313239	39313262	21	+	28162770	MONOMAC1	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.8559120328894055	[106]	[221]	7	hSpCas9	negative selection	11982335
39298513	39298536	21	-	28162770	MONOMAC1	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.7926507785043089	[350]	[696]	7	hSpCas9	negative selection	11982336
39313089	39313112	21	-	28162770	MONOMAC1	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	2.0435911457259603	[72]	[344]	9	hSpCas9	negative selection	11982337
39258486	39258509	21	-	28162770	MONOMAC1	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-1.15804271544369	[145]	[74]	-7	hSpCas9	negative selection	11982338
39312876	39312899	21	-	28162770	OCIAML2	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	-0.21581592621333578	[65]	[314]	-2	hSpCas9	negative selection	12151695
39202426	39202449	21	-	28162770	OCIAML2	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	-0.18522760637991278	[31]	[155]	-1	hSpCas9	negative selection	12151696
39312840	39312863	21	-	28162770	OCIAML2	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	-0.008002867445057182	[40]	[225]	0	hSpCas9	negative selection	12151697
39313436	39313459	21	+	28162770	OCIAML2	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.2309775943312653	[94]	[617]	2	hSpCas9	negative selection	12151698
39313071	39313094	21	-	28162770	OCIAML2	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	0.43269415534616507	[53]	[403]	4	hSpCas9	negative selection	12151699
39313449	39313472	21	+	28162770	OCIAML2	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	-0.5045771571654989	[42]	[167]	-4	hSpCas9	negative selection	12151700
39313239	39313262	21	+	28162770	OCIAML2	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	-0.770190107101069	[47]	[155]	-5	hSpCas9	negative selection	12151701
39298513	39298536	21	-	28162770	OCIAML2	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.5309939172375029	[110]	[888]	5	hSpCas9	negative selection	12151702
39313089	39313112	21	-	28162770	OCIAML2	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	0.3495491371730267	[15]	[112]	3	hSpCas9	negative selection	12151703
39258486	39258509	21	-	28162770	OCIAML2	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	-0.27625178007530987	[25]	[118]	-2	hSpCas9	negative selection	12151704
39312876	39312899	21	-	28162770	OCIAML3	viability	GTTGCCGAAGAGATTGGACTGGG	BRWD1	ENSG00000185658	0.18279821837383414	[74]	[256]	1	hSpCas9	negative selection	12321061
39202426	39202449	21	-	28162770	OCIAML3	viability	GGAACCCACAAGACAAGTGCTGG	BRWD1	ENSG00000185658	0.07895134139482185	[52]	[168]	0	hSpCas9	negative selection	12321062
39312840	39312863	21	-	28162770	OCIAML3	viability	CAACAGGAGCTACGAGGAGTTGG	BRWD1	ENSG00000185658	0.9572717341407045	[64]	[380]	8	hSpCas9	negative selection	12321063
39313436	39313459	21	+	28162770	OCIAML3	viability	GTCTTACCCGACTCGATGAGAGG	BRWD1	ENSG00000185658	0.5715188972206322	[145]	[654]	5	hSpCas9	negative selection	12321064
39313071	39313094	21	-	28162770	OCIAML3	viability	GCAGGAGCTGGAGCAGTACCAGG	BRWD1	ENSG00000185658	1.4131167941092184	[100]	[811]	9	hSpCas9	negative selection	12321065
39313449	39313472	21	+	28162770	OCIAML3	viability	CGATGAGAGGCACCGGGCGTCGG	BRWD1	ENSG00000185658	0.8101062099184442	[57]	[306]	7	hSpCas9	negative selection	12321066
39313239	39313262	21	+	28162770	OCIAML3	viability	ACCTGGGCCGCTCTCCGACACGG	BRWD1	ENSG00000185658	0.3615982403173835	[65]	[255]	3	hSpCas9	negative selection	12321067
39298513	39298536	21	-	28162770	OCIAML3	viability	CCAGCGCATCGGTCCTATGTTGG	BRWD1	ENSG00000185658	0.5315232417596956	[186]	[815]	5	hSpCas9	negative selection	12321068
39313089	39313112	21	-	28162770	OCIAML3	viability	TCGGCCGCAGGTGCTGGTGCAGG	BRWD1	ENSG00000185658	1.9133339632745192	[34]	[397]	9	hSpCas9	negative selection	12321069
39258486	39258509	21	-	28162770	OCIAML3	viability	GGTGAAGAAACACCCCGGAGAGG	BRWD1	ENSG00000185658	1.1090106219187053	[42]	[279]	8	hSpCas9	negative selection	12321070