Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23581
• Symbol: CASP14
• Description: caspase 14

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP14

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15053807	15053830	19	+	26472758	Jiyoye	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.626771950417464	[128]	[62]	-4	hSpCas9	negative selection	23729
15053822	15053845	19	+	26472758	Jiyoye	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.28140975028944015	[302]	[187]	-2	hSpCas9	negative selection	23730
15053524	15053547	19	+	26472758	Jiyoye	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-0.22766302585485243	[308]	[198]	-2	hSpCas9	negative selection	23731
15053610	15053633	19	+	26472758	Jiyoye	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.3318872542016364	[117]	[111]	2	hSpCas9	negative selection	23732
15055263	15055286	19	-	26472758	Jiyoye	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.32489141324749365	[97]	[58]	-2	hSpCas9	negative selection	23733
15052244	15052267	19	+	26472758	Jiyoye	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	2.0653868642576683	[31]	[100]	8	hSpCas9	negative selection	23734
15052261	15052284	19	-	26472758	Jiyoye	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.4071753815058735	[79]	[79]	3	hSpCas9	negative selection	23735
15053541	15053564	19	+	26472758	Jiyoye	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.6966819987008583	[8]	[10]	5	hSpCas9	negative selection	23736
15053621	15053644	19	-	26472758	Jiyoye	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.47083409411551624	[203]	[110]	-3	hSpCas9	negative selection	23737
15055166	15055189	19	+	26472758	Jiyoye	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.006213067438752634	[135]	[102]	0	hSpCas9	negative selection	23738
15053807	15053830	19	+	26472758	KBM7	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.13053106590885727	[362,305]	[227,120]	1	hSpCas9	negative selection	214847
15053822	15053845	19	+	26472758	KBM7	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.5318356630911446	[886,819]	[765,414]	6	hSpCas9	negative selection	214848
15053524	15053547	19	+	26472758	KBM7	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.4383841574305978	[981,701]	[643,427]	5	hSpCas9	negative selection	214849
15053610	15053633	19	+	26472758	KBM7	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.43613053197896273	[496,214]	[276,165]	5	hSpCas9	negative selection	214850
15055263	15055286	19	-	26472758	KBM7	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.5405926088261325	[333,259]	[134,260]	6	hSpCas9	negative selection	214851
15052244	15052267	19	+	26472758	KBM7	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.0002717806122187749	[456,191]	[222,78]	0	hSpCas9	negative selection	214852
15052261	15052284	19	-	26472758	KBM7	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.9731835228515568	[440,299]	[97,77]	-6	hSpCas9	negative selection	214853
15053541	15053564	19	+	26472758	KBM7	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	1.1746705625852003	[78,52]	[40,93]	9	hSpCas9	negative selection	214854
15053621	15053644	19	-	26472758	KBM7	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.26451931884955904	[786,671]	[453,371]	2	hSpCas9	negative selection	214855
15055166	15055189	19	+	26472758	KBM7	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.5690655118344711	[311,266]	[166,231]	6	hSpCas9	negative selection	214856
15053807	15053830	19	+	26472758	Raji	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.9484799400225392	[162]	[72]	8	hSpCas9	negative selection	405965
15053822	15053845	19	+	26472758	Raji	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.4576105491149607	[573]	[96]	-4	hSpCas9	negative selection	405966
15053524	15053547	19	+	26472758	Raji	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.21351188623494277	[523]	[140]	2	hSpCas9	negative selection	405967
15053610	15053633	19	+	26472758	Raji	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.1472762624971122	[213]	[54]	1	hSpCas9	negative selection	405968
15055263	15055286	19	-	26472758	Raji	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.7440939399163126	[165]	[22]	-5	hSpCas9	negative selection	405969
15052244	15052267	19	+	26472758	Raji	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	-0.6999713866840047	[188]	[26]	-5	hSpCas9	negative selection	405970
15052261	15052284	19	-	26472758	Raji	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.04538674502964596	[208]	[46]	0	hSpCas9	negative selection	405971
15053541	15053564	19	+	26472758	Raji	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.10738353537359924	[27]	[6]	1	hSpCas9	negative selection	405972
15053621	15053644	19	-	26472758	Raji	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.2957406423617435	[401]	[75]	-2	hSpCas9	negative selection	405973
15055166	15055189	19	+	26472758	Raji	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.05572141555110685	[198]	[47]	0	hSpCas9	negative selection	405974
15053807	15053830	19	+	26472758	K562	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-2.414321699194257	[340]	[53]	-8	hSpCas9	negative selection	597083
15053822	15053845	19	+	26472758	K562	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.1648381669372827	[558]	[528]	1	hSpCas9	negative selection	597084
15053524	15053547	19	+	26472758	K562	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-0.1148079086438909	[861]	[671]	-1	hSpCas9	negative selection	597085
15053610	15053633	19	+	26472758	K562	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.14950708064098	[266]	[249]	1	hSpCas9	negative selection	597086
15055263	15055286	19	-	26472758	K562	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.49842343283642854	[327]	[195]	-3	hSpCas9	negative selection	597087
15052244	15052267	19	+	26472758	K562	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.26579237845901377	[267]	[271]	2	hSpCas9	negative selection	597088
15052261	15052284	19	-	26472758	K562	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.17256704340191875	[246]	[184]	-1	hSpCas9	negative selection	597089
15053541	15053564	19	+	26472758	K562	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.6693040129016379	[72]	[97]	5	hSpCas9	negative selection	597090
15053621	15053644	19	-	26472758	K562	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.8525708557594927	[575]	[877]	7	hSpCas9	negative selection	597091
15055166	15055189	19	+	26472758	K562	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	1.032914622472735	[307]	[531]	8	hSpCas9	negative selection	597092
15052257	15052280	19	+	26627737	DLD1	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.09990482435968873	[187]	[72,31,57]	-1	hSpCas9	negative selection	802991
15053806	15053829	19	+	26627737	DLD1	viability	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.25626310707312083	[412]	[72,156,97]	-3	hSpCas9	negative selection	802992
15053937	15053960	19	+	26627737	DLD1	viability	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.9892712017678884	[250]	[100,184,178]	8	hSpCas9	negative selection	802993
15055438	15055461	19	+	26627737	DLD1	viability	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.2507953861565373	[946]	[285,387,379]	2	hSpCas9	negative selection	802994
15055461	15055484	19	+	26627737	DLD1	viability	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.43573662288974524	[1005]	[170,259,262]	-4	hSpCas9	negative selection	802995
15056061	15056084	19	-	26627737	DLD1	viability	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.7163750842401371	[252]	[128,90,162]	7	hSpCas9	negative selection	802996
15052257	15052280	19	+	26627737	GBM cells	viability after 5 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.266895018084395	[174]	[64,90]	-4	hSpCas9	negative selection	885306
15053806	15053829	19	+	26627737	GBM cells	viability after 5 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	0.6461478045057186	[139]	[118,115]	8	hSpCas9	negative selection	885307
15053937	15053960	19	+	26627737	GBM cells	viability after 5 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.4816379034108422	[214]	[179,141]	7	hSpCas9	negative selection	885308
15055438	15055461	19	+	26627737	GBM cells	viability after 5 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.3119462382741527	[539]	[387,330]	5	hSpCas9	negative selection	885309
15055461	15055484	19	+	26627737	GBM cells	viability after 5 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.6681267178382081	[439]	[167,128]	-8	hSpCas9	negative selection	885310
15056061	15056084	19	-	26627737	GBM cells	viability after 5 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.06972195420497929	[181]	[109,75]	-1	hSpCas9	negative selection	885311
15052257	15052280	19	+	26627737	GBM cells	viability after 13 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.02169918601935994	[174]	[118,77]	0	hSpCas9	negative selection	967621
15053806	15053829	19	+	26627737	GBM cells	viability after 13 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	0.39412811492580485	[139]	[90,106]	5	hSpCas9	negative selection	967622
15053937	15053960	19	+	26627737	GBM cells	viability after 13 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.2782686113960522	[214]	[114,162]	3	hSpCas9	negative selection	967623
15055438	15055461	19	+	26627737	GBM cells	viability after 13 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.029360155848858538	[539]	[330,272]	0	hSpCas9	negative selection	967624
15055461	15055484	19	+	26627737	GBM cells	viability after 13 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.6704378994503314	[439]	[149,149]	-7	hSpCas9	negative selection	967625
15056061	15056084	19	-	26627737	GBM cells	viability after 13 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.23577553167108867	[181]	[79,86]	-3	hSpCas9	negative selection	967626
15052257	15052280	19	+	26627737	GBM cells	viability after 21 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.27339668093704383	[174]	[116,112]	3	hSpCas9	negative selection	1049936
15053806	15053829	19	+	26627737	GBM cells	viability after 21 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	1.0811700382586307	[139]	[150,169]	9	hSpCas9	negative selection	1049937
15053937	15053960	19	+	26627737	GBM cells	viability after 21 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.5561600715832713	[214]	[165,176]	5	hSpCas9	negative selection	1049938
15055438	15055461	19	+	26627737	GBM cells	viability after 21 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.36982197620497503	[539]	[237,216]	-3	hSpCas9	negative selection	1049939
15055461	15055484	19	+	26627737	GBM cells	viability after 21 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.5283097103983683	[439]	[159,170]	-5	hSpCas9	negative selection	1049940
15056061	15056084	19	-	26627737	GBM cells	viability after 21 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.5985502539239694	[181]	[69,60]	-5	hSpCas9	negative selection	1049941
15052257	15052280	19	+	26627737	RPE1	viability after 9 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-1.3521916051326317	[575]	[43,104]	-7	hSpCas9	negative selection	1132251
15053806	15053829	19	+	26627737	RPE1	viability after 9 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	1.5570250003701454	[288]	[191,361]	8	hSpCas9	negative selection	1132252
15053937	15053960	19	+	26627737	RPE1	viability after 9 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-2.0044835984765887	[1207]	[95,91]	-8	hSpCas9	negative selection	1132253
15055438	15055461	19	+	26627737	RPE1	viability after 9 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.041430438265496194	[2244]	[654,718]	0	hSpCas9	negative selection	1132254
15055461	15055484	19	+	26627737	RPE1	viability after 9 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.5210750374646146	[2205]	[489,469]	-4	hSpCas9	negative selection	1132255
15056061	15056084	19	-	26627737	RPE1	viability after 9 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	2.573410071953056	[78]	[65,251]	9	hSpCas9	negative selection	1132256
15052257	15052280	19	+	26627737	RPE1	viability after 12 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.3515477682737404	[575]	[79,164]	-2	hSpCas9	negative selection	1214566
15053806	15053829	19	+	26627737	RPE1	viability after 12 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	1.660680990212905	[288]	[244,245]	8	hSpCas9	negative selection	1214567
15053937	15053960	19	+	26627737	RPE1	viability after 12 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-2.6323725564999636	[1207]	[46,57]	-9	hSpCas9	negative selection	1214568
15055438	15055461	19	+	26627737	RPE1	viability after 12 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.010595588231278263	[2244]	[555,643]	0	hSpCas9	negative selection	1214569
15055461	15055484	19	+	26627737	RPE1	viability after 12 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.508487694666791	[2205]	[471,357]	-3	hSpCas9	negative selection	1214570
15056061	15056084	19	-	26627737	RPE1	viability after 12 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	3.0178762879809224	[78]	[134,210]	9	hSpCas9	negative selection	1214571
15052257	15052280	19	+	26627737	RPE1	viability after 15 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.13178698290653112	[575]	[120,233]	0	hSpCas9	negative selection	1296881
15053806	15053829	19	+	26627737	RPE1	viability after 15 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	1.642008392473862	[288]	[274,235]	8	hSpCas9	negative selection	1296882
15053937	15053960	19	+	26627737	RPE1	viability after 15 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-2.301335580411044	[1207]	[50,86]	-8	hSpCas9	negative selection	1296883
15055438	15055461	19	+	26627737	RPE1	viability after 15 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.11196139756778956	[2244]	[635,540]	0	hSpCas9	negative selection	1296884
15055461	15055484	19	+	26627737	RPE1	viability after 15 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.2909739710437873	[2205]	[675,349]	-2	hSpCas9	negative selection	1296885
15056061	15056084	19	-	26627737	RPE1	viability after 15 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	2.580105860580315	[78]	[97,167]	9	hSpCas9	negative selection	1296886
15052257	15052280	19	+	26627737	RPE1	viability after 18 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.10332471804865256	[575]	[49,291]	0	hSpCas9	negative selection	1379196
15053806	15053829	19	+	26627737	RPE1	viability after 18 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	1.5307404270725482	[288]	[147,307]	7	hSpCas9	negative selection	1379197
15053937	15053960	19	+	26627737	RPE1	viability after 18 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-3.206230123610071	[1207]	[0,71]	-9	hSpCas9	negative selection	1379198
15055438	15055461	19	+	26627737	RPE1	viability after 18 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.07423816091199686	[2244]	[647,626]	0	hSpCas9	negative selection	1379199
15055461	15055484	19	+	26627737	RPE1	viability after 18 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.13065168031482766	[2205]	[624,456]	-1	hSpCas9	negative selection	1379200
15056061	15056084	19	-	26627737	RPE1	viability after 18 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	2.592336572293899	[78]	[86,172]	9	hSpCas9	negative selection	1379201
15052257	15052280	19	+	26627737	HeLa	viability after 8 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.8275693481627058	[156]	[78,0,43]	-7	hSpCas9	negative selection	1461511
15053806	15053829	19	+	26627737	HeLa	viability after 8 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.5033448220712716	[400]	[136,32,196]	-5	hSpCas9	negative selection	1461512
15053937	15053960	19	+	26627737	HeLa	viability after 8 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.6617106996008839	[354]	[191,246,279]	5	hSpCas9	negative selection	1461513
15055438	15055461	19	+	26627737	HeLa	viability after 8 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.9392436320293382	[408]	[312,354,348]	7	hSpCas9	negative selection	1461514
15055461	15055484	19	+	26627737	HeLa	viability after 8 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.28023453568996876	[574]	[205,189,220]	-3	hSpCas9	negative selection	1461515
15056061	15056084	19	-	26627737	HeLa	viability after 8 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-1.5391233797404895	[406]	[125,22,48]	-9	hSpCas9	negative selection	1461516
15052257	15052280	19	+	26627737	HeLa	viability after 12 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.881687741940975	[156]	[134,110,113]	6	hSpCas9	negative selection	1543826
15053806	15053829	19	+	26627737	HeLa	viability after 12 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.7701926735662241	[400]	[96,82,112]	-6	hSpCas9	negative selection	1543827
15053937	15053960	19	+	26627737	HeLa	viability after 12 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-0.34582734471524323	[354]	[178,116,51]	-3	hSpCas9	negative selection	1543828
15055438	15055461	19	+	26627737	HeLa	viability after 12 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.4033498915902256	[408]	[201,185,285]	3	hSpCas9	negative selection	1543829
15055461	15055484	19	+	26627737	HeLa	viability after 12 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.27436187380613364	[574]	[149,345,355]	2	hSpCas9	negative selection	1543830
15056061	15056084	19	-	26627737	HeLa	viability after 12 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.5395825747210146	[406]	[310,47,0]	-5	hSpCas9	negative selection	1543831
15052257	15052280	19	+	26627737	HeLa	viability after 15 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.8078557439559617	[156]	[13,32,64]	-6	hSpCas9	negative selection	1626141
15053806	15053829	19	+	26627737	HeLa	viability after 15 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.7841652322642766	[400]	[163,78,35]	-6	hSpCas9	negative selection	1626142
15053937	15053960	19	+	26627737	HeLa	viability after 15 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-1.2167266577443534	[354]	[54,52,79]	-8	hSpCas9	negative selection	1626143
15055438	15055461	19	+	26627737	HeLa	viability after 15 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.4939031061547681	[408]	[156,269,280]	4	hSpCas9	negative selection	1626144
15055461	15055484	19	+	26627737	HeLa	viability after 15 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.6020939882359815	[574]	[288,371,409]	5	hSpCas9	negative selection	1626145
15056061	15056084	19	-	26627737	HeLa	viability after 15 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.8976715623902416	[406]	[122,82,57]	-7	hSpCas9	negative selection	1626146
15052257	15052280	19	+	26627737	HeLa	viability after 18 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.8797732380491707	[156]	[6,25,64]	-6	hSpCas9	negative selection	1708456
15053806	15053829	19	+	26627737	HeLa	viability after 18 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.7621908783415506	[400]	[109,68,35]	-6	hSpCas9	negative selection	1708457
15053937	15053960	19	+	26627737	HeLa	viability after 18 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-1.147009305560239	[354]	[37,49,79]	-7	hSpCas9	negative selection	1708458
15055438	15055461	19	+	26627737	HeLa	viability after 18 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.4651652842640234	[408]	[99,218,280]	4	hSpCas9	negative selection	1708459
15055461	15055484	19	+	26627737	HeLa	viability after 18 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.6225505127330384	[574]	[198,313,409]	5	hSpCas9	negative selection	1708460
15056061	15056084	19	-	26627737	HeLa	viability after 18 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.8985885812711258	[406]	[82,67,57]	-7	hSpCas9	negative selection	1708461
15052257	15052280	19	+	26627737	HCT116	viability after 6 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	3.7841911869739113	[155]	[32,505]	9	hSpCas9	negative selection	1790771
15053806	15053829	19	+	26627737	HCT116	viability after 6 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.8344001115794524	[968]	[29,115]	-5	hSpCas9	negative selection	1790772
15053937	15053960	19	+	26627737	HCT116	viability after 6 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-0.0993011114362316	[729]	[139,88]	0	hSpCas9	negative selection	1790773
15055438	15055461	19	+	26627737	HCT116	viability after 6 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	1.6711912778652072	[1011]	[166,693]	8	hSpCas9	negative selection	1790774
15055461	15055484	19	+	26627737	HCT116	viability after 6 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.042308223035935066	[835]	[115,145]	0	hSpCas9	negative selection	1790775
15056061	15056084	19	-	26627737	HCT116	viability after 6 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.5424510972257544	[546]	[69,52]	-3	hSpCas9	negative selection	1790776
15052257	15052280	19	+	26627737	HCT116	viability after 8 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.9118745230195557	[81]	[124,65,64]	8	hSpCas9	negative selection	1873086
15053806	15053829	19	+	26627737	HCT116	viability after 8 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.44766266177706465	[317]	[103,151,128]	-5	hSpCas9	negative selection	1873087
15053937	15053960	19	+	26627737	HCT116	viability after 8 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.08700147843361744	[239]	[137,195,87]	1	hSpCas9	negative selection	1873088
15055438	15055461	19	+	26627737	HCT116	viability after 8 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.20847768882038176	[655]	[272,285,377]	-2	hSpCas9	negative selection	1873089
15055461	15055484	19	+	26627737	HCT116	viability after 8 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.02631429294863441	[516]	[301,373,164]	0	hSpCas9	negative selection	1873090
15056061	15056084	19	-	26627737	HCT116	viability after 8 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.1869301462367537	[187]	[104,85,161]	2	hSpCas9	negative selection	1873091
15052257	15052280	19	+	26627737	HCT116	viability after 9 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.37687998776180254	[155]	[119,1]	3	hSpCas9	negative selection	1955401
15053806	15053829	19	+	26627737	HCT116	viability after 9 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.4017145904970471	[968]	[77,288]	-3	hSpCas9	negative selection	1955402
15053937	15053960	19	+	26627737	HCT116	viability after 9 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.49486982113309363	[729]	[105,407]	3	hSpCas9	negative selection	1955403
15055438	15055461	19	+	26627737	HCT116	viability after 9 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.1819303119945549	[1011]	[515,140]	1	hSpCas9	negative selection	1955404
15055461	15055484	19	+	26627737	HCT116	viability after 9 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.11089747968030567	[835]	[187,282]	0	hSpCas9	negative selection	1955405
15056061	15056084	19	-	26627737	HCT116	viability after 9 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.11301407433215005	[546]	[62,191]	-1	hSpCas9	negative selection	1955406
15052257	15052280	19	+	26627737	HCT116	viability after 12 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.6382128389141843	[81]	[69,68,61]	6	hSpCas9	negative selection	2037716
15053806	15053829	19	+	26627737	HCT116	viability after 12 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.500034599501026	[317]	[130,143,78]	-5	hSpCas9	negative selection	2037717
15053937	15053960	19	+	26627737	HCT116	viability after 12 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.9444802981713735	[239]	[275,272,176]	7	hSpCas9	negative selection	2037718
15055438	15055461	19	+	26627737	HCT116	viability after 12 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.32684716386111823	[655]	[209,304,315]	-3	hSpCas9	negative selection	2037719
15055461	15055484	19	+	26627737	HCT116	viability after 12 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.14760627089692668	[516]	[261,271,200]	-1	hSpCas9	negative selection	2037720
15056061	15056084	19	-	26627737	HCT116	viability after 12 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.11389007355952796	[187]	[38,70,167]	-1	hSpCas9	negative selection	2037721
15052257	15052280	19	+	26627737	HCT116	viability after 15 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	1.219286893784071	[81]	[60,150,110]	8	hSpCas9	negative selection	2120031
15053806	15053829	19	+	26627737	HCT116	viability after 15 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.1242535323254017	[317]	[194,142,167]	-1	hSpCas9	negative selection	2120032
15053937	15053960	19	+	26627737	HCT116	viability after 15 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.5949271746497773	[239]	[133,230,249]	5	hSpCas9	negative selection	2120033
15055438	15055461	19	+	26627737	HCT116	viability after 15 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.4223263372985794	[655]	[308,274,262]	-4	hSpCas9	negative selection	2120034
15055461	15055484	19	+	26627737	HCT116	viability after 15 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.03498059159904132	[516]	[293,293,281]	0	hSpCas9	negative selection	2120035
15056061	15056084	19	-	26627737	HCT116	viability after 15 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.3774576938870903	[187]	[114,104,196]	3	hSpCas9	negative selection	2120036
15052257	15052280	19	+	26627737	HCT116	viability after 18 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.9930401615145675	[81]	[37,58,143]	7	hSpCas9	negative selection	2202346
15053806	15053829	19	+	26627737	HCT116	viability after 18 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.8198347236095771	[317]	[73,111,72]	-6	hSpCas9	negative selection	2202347
15053937	15053960	19	+	26627737	HCT116	viability after 18 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.7782481478005672	[239]	[150,209,236]	6	hSpCas9	negative selection	2202348
15055438	15055461	19	+	26627737	HCT116	viability after 18 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.2814388573906489	[655]	[237,302,237]	-3	hSpCas9	negative selection	2202349
15055461	15055484	19	+	26627737	HCT116	viability after 18 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	-0.26099157994165423	[516]	[166,291,158]	-2	hSpCas9	negative selection	2202350
15056061	15056084	19	-	26627737	HCT116	viability after 18 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.3672163999369443	[187]	[66,40,106]	-3	hSpCas9	negative selection	2202351
15052244	15052267	19	+	24336569	HL60	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.07089605136045574	[201]	[448]	0	hSpCas9	negative selection	2254456
15052251	15052274	19	+	24336569	HL60	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	-0.031788941604706356	[470]	[974]	0	hSpCas9	negative selection	2254457
15052257	15052280	19	+	24336569	HL60	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.5789955076302062	[272]	[862]	5	hSpCas9	negative selection	2254458
15053478	15053501	19	-	24336569	HL60	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	-0.537143584405086	[551]	[804]	-5	hSpCas9	negative selection	2254459
15053490	15053513	19	+	24336569	HL60	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	2.954004102983182	[112]	[1852]	9	hSpCas9	negative selection	2254460
15053504	15053527	19	-	24336569	HL60	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.42303951961243197	[380]	[1080]	4	hSpCas9	negative selection	2254461
15053513	15053536	19	-	24336569	HL60	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-0.1072950336365397	[957]	[1881]	-1	hSpCas9	negative selection	2254462
15053519	15053542	19	+	24336569	HL60	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	-1.0814641006288976	[0]	[0]	-7	hSpCas9	negative selection	2254463
15053524	15053547	19	+	24336569	HL60	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-1.1806195672884578	[270]	[252]	-8	hSpCas9	negative selection	2254464
15053531	15053554	19	-	24336569	HL60	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.1316984031490327	[262]	[507]	-1	hSpCas9	negative selection	2254465
15052244	15052267	19	+	24336569	KBM7	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.22055878701951487	[336]	[1070]	2	hSpCas9	negative selection	2321633
15052251	15052274	19	+	24336569	KBM7	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	-0.12844612037408443	[619]	[1546]	-1	hSpCas9	negative selection	2321634
15052257	15052280	19	+	24336569	KBM7	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.41264540643949543	[203]	[417]	-3	hSpCas9	negative selection	2321635
15053478	15053501	19	-	24336569	KBM7	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	0.7739129470417274	[228]	[1067]	7	hSpCas9	negative selection	2321636
15053490	15053513	19	+	24336569	KBM7	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	3.468356538662643	[52]	[1599]	9	hSpCas9	negative selection	2321637
15053504	15053527	19	-	24336569	KBM7	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.14067337410645847	[437]	[1316]	1	hSpCas9	negative selection	2321638
15053513	15053536	19	-	24336569	KBM7	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	1.3010259533629374	[357]	[2405]	9	hSpCas9	negative selection	2321639
15053519	15053542	19	+	24336569	KBM7	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	0.8140883735210056	[43]	[210]	7	hSpCas9	negative selection	2321640
15053524	15053547	19	+	24336569	KBM7	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	1.3558446739188066	[104]	[732]	9	hSpCas9	negative selection	2321641
15053531	15053554	19	-	24336569	KBM7	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.802399056459465	[184]	[879]	7	hSpCas9	negative selection	2321642
15049376	15049399	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACAGCTGTGGTGTGGAAATGG	CASP14	ENSG00000105141	3.2917116298758016	[96,39]	[257,27]	8	dCas9-VP64	positive selection	2441635
15049376	15049399	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACAGCTGTGGTGTGGAAATGG	CASP14	ENSG00000105141	0.3143665887887608	[95,77]	[35,34]	2	dCas9-VP64	positive selection	2536890
15053786	15053809	19	+	27260157	DLD1	viability	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	-0.655491749885631	[]	[]	-5	hSpCas9	negative selection	2581467
15053559	15053582	19	-	27260157	DLD1	viability	ACATGTGTTCCAGAGCATCCAGG	CASP14	ENSG00000105141	0.586244481388246	[]	[]	8	hSpCas9	negative selection	2581474
15052251	15052274	19	+	27260157	DLD1	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	-0.321968256892001	[]	[]	-3	hSpCas9	negative selection	2581961
15052261	15052284	19	-	27260157	DLD1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.398556636848266	[]	[]	4	hSpCas9	negative selection	2584160
15053776	15053799	19	-	27260157	DLD1	viability	ACAACTGACGGGATCTTCCCGGG	CASP14	ENSG00000105141	-1.10691075148658	[]	[]	-7	hSpCas9	negative selection	2587652
15052257	15052280	19	+	27260157	DLD1	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.228103079412758	[]	[]	-2	hSpCas9	negative selection	2604365
15053531	15053554	19	-	27260157	DLD1	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.430159356599357	[]	[]	7	hSpCas9	negative selection	2607783
15053513	15053536	19	-	27260157	DLD1	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-0.311541586372144	[]	[]	-3	hSpCas9	negative selection	2612165
15053758	15053781	19	+	27260157	DLD1	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	-0.501641676893985	[]	[]	-4	hSpCas9	negative selection	2614753
15053519	15053542	19	+	27260157	DLD1	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	0.845243464460824	[]	[]	9	hSpCas9	negative selection	2614836
15053478	15053501	19	-	27260157	DLD1	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	0.447277842978943	[]	[]	7	hSpCas9	negative selection	2618462
15053759	15053782	19	-	27260157	DLD1	viability	CCCGGGAATCGATGGCCTGCTGG	CASP14	ENSG00000105141	1.41783728181104	[]	[]	9	hSpCas9	negative selection	2618978
15053524	15053547	19	+	27260157	DLD1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.6047878273508	[]	[]	8	hSpCas9	negative selection	2621042
15053490	15053513	19	+	27260157	DLD1	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	-0.144539961814839	[]	[]	-1	hSpCas9	negative selection	2640765
15053504	15053527	19	-	27260157	DLD1	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	-0.148380903753395	[]	[]	-1	hSpCas9	negative selection	2644014
15053729	15053752	19	+	27260157	DLD1	viability	CCAGCAATTCCAGGAAGAGCTGG	CASP14	ENSG00000105141	0.804206738112126	[]	[]	9	hSpCas9	negative selection	2648643
15053786	15053809	19	+	27260157	HT1080	viability	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	-0.221213293050914	[]	[]	0	hSpCas9	negative selection	2657597
15053559	15053582	19	-	27260157	HT1080	viability	ACATGTGTTCCAGAGCATCCAGG	CASP14	ENSG00000105141	0.899738476847594	[]	[]	7	hSpCas9	negative selection	2657604
15052251	15052274	19	+	27260157	HT1080	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	-0.0103224834628702	[]	[]	0	hSpCas9	negative selection	2658091
15052261	15052284	19	-	27260157	HT1080	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.230672553487029	[]	[]	2	hSpCas9	negative selection	2660290
15053776	15053799	19	-	27260157	HT1080	viability	ACAACTGACGGGATCTTCCCGGG	CASP14	ENSG00000105141	-0.0261092235570492	[]	[]	0	hSpCas9	negative selection	2663782
15052257	15052280	19	+	27260157	HT1080	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.967375972534555	[]	[]	-8	hSpCas9	negative selection	2680495
15053531	15053554	19	-	27260157	HT1080	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.185382188589533	[]	[]	0	hSpCas9	negative selection	2683913
15053513	15053536	19	-	27260157	HT1080	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-0.341423861954854	[]	[]	-7	hSpCas9	negative selection	2688295
15053758	15053781	19	+	27260157	HT1080	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	-0.378607795692897	[]	[]	-7	hSpCas9	negative selection	2690883
15053519	15053542	19	+	27260157	HT1080	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	0.375554273270525	[]	[]	3	hSpCas9	negative selection	2690966
15053478	15053501	19	-	27260157	HT1080	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	-0.176693092361727	[]	[]	0	hSpCas9	negative selection	2694592
15053759	15053782	19	-	27260157	HT1080	viability	CCCGGGAATCGATGGCCTGCTGG	CASP14	ENSG00000105141	1.71896598546672	[]	[]	9	hSpCas9	negative selection	2695108
15053524	15053547	19	+	27260157	HT1080	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.486627654148579	[]	[]	4	hSpCas9	negative selection	2697172
15053490	15053513	19	+	27260157	HT1080	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	0.215909851174517	[]	[]	2	hSpCas9	negative selection	2716895
15053504	15053527	19	-	27260157	HT1080	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.834247813291629	[]	[]	7	hSpCas9	negative selection	2720144
15053729	15053752	19	+	27260157	HT1080	viability	CCAGCAATTCCAGGAAGAGCTGG	CASP14	ENSG00000105141	0.431878425957532	[]	[]	4	hSpCas9	negative selection	2724773
15053786	15053809	19	+	27260157	MKN45	viability	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.280315545880432	[]	[]	5	hSpCas9	negative selection	2733727
15053559	15053582	19	-	27260157	MKN45	viability	ACATGTGTTCCAGAGCATCCAGG	CASP14	ENSG00000105141	0.413583830443557	[]	[]	6	hSpCas9	negative selection	2733734
15052251	15052274	19	+	27260157	MKN45	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	-0.432137564944079	[]	[]	-6	hSpCas9	negative selection	2734221
15052261	15052284	19	-	27260157	MKN45	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.76543841059837	[]	[]	-7	hSpCas9	negative selection	2736420
15053776	15053799	19	-	27260157	MKN45	viability	ACAACTGACGGGATCTTCCCGGG	CASP14	ENSG00000105141	-0.201299531275179	[]	[]	0	hSpCas9	negative selection	2739912
15052257	15052280	19	+	27260157	MKN45	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.430071185341056	[]	[]	-6	hSpCas9	negative selection	2756625
15053531	15053554	19	-	27260157	MKN45	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.277420322414679	[]	[]	-1	hSpCas9	negative selection	2760043
15053513	15053536	19	-	27260157	MKN45	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-0.906821220009248	[]	[]	-7	hSpCas9	negative selection	2764425
15053758	15053781	19	+	27260157	MKN45	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	-0.354911773978074	[]	[]	-1	hSpCas9	negative selection	2767013
15053519	15053542	19	+	27260157	MKN45	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	1.34728489376461	[]	[]	9	hSpCas9	negative selection	2767096
15053478	15053501	19	-	27260157	MKN45	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	0.122862741206127	[]	[]	4	hSpCas9	negative selection	2770722
15053759	15053782	19	-	27260157	MKN45	viability	CCCGGGAATCGATGGCCTGCTGG	CASP14	ENSG00000105141	1.49328674457987	[]	[]	9	hSpCas9	negative selection	2771238
15053524	15053547	19	+	27260157	MKN45	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.517376344558526	[]	[]	6	hSpCas9	negative selection	2773302
15053490	15053513	19	+	27260157	MKN45	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	-0.206992801776982	[]	[]	0	hSpCas9	negative selection	2793025
15053504	15053527	19	-	27260157	MKN45	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.0404103382186105	[]	[]	0	hSpCas9	negative selection	2796274
15053729	15053752	19	+	27260157	MKN45	viability	CCAGCAATTCCAGGAAGAGCTGG	CASP14	ENSG00000105141	1.07155898265	[]	[]	8	hSpCas9	negative selection	2800903
15053786	15053809	19	+	27260157	RKO	viability	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	-0.343338419188173	[]	[]	-6	hSpCas9	negative selection	2809857
15053559	15053582	19	-	27260157	RKO	viability	ACATGTGTTCCAGAGCATCCAGG	CASP14	ENSG00000105141	0.891888426589972	[]	[]	8	hSpCas9	negative selection	2809864
15052251	15052274	19	+	27260157	RKO	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	0.107910477608155	[]	[]	0	hSpCas9	negative selection	2810351
15052261	15052284	19	-	27260157	RKO	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.31797984421679	[]	[]	-6	hSpCas9	negative selection	2812550
15053776	15053799	19	-	27260157	RKO	viability	ACAACTGACGGGATCTTCCCGGG	CASP14	ENSG00000105141	0.215352364474301	[]	[]	1	hSpCas9	negative selection	2816042
15052257	15052280	19	+	27260157	RKO	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.703760515669543	[]	[]	-7	hSpCas9	negative selection	2832755
15053531	15053554	19	-	27260157	RKO	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.0215051789499446	[]	[]	0	hSpCas9	negative selection	2836173
15053513	15053536	19	-	27260157	RKO	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-0.0606584747736411	[]	[]	0	hSpCas9	negative selection	2840555
15053758	15053781	19	+	27260157	RKO	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	-0.0190153718012664	[]	[]	0	hSpCas9	negative selection	2843143
15053519	15053542	19	+	27260157	RKO	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	1.35040737556829	[]	[]	9	hSpCas9	negative selection	2843226
15053478	15053501	19	-	27260157	RKO	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	0.0171425680987699	[]	[]	0	hSpCas9	negative selection	2846852
15053759	15053782	19	-	27260157	RKO	viability	CCCGGGAATCGATGGCCTGCTGG	CASP14	ENSG00000105141	0.942176032423258	[]	[]	8	hSpCas9	negative selection	2847368
15053524	15053547	19	+	27260157	RKO	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.536816977247953	[]	[]	3	hSpCas9	negative selection	2849432
15053490	15053513	19	+	27260157	RKO	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	-0.24775925975587	[]	[]	-1	hSpCas9	negative selection	2869155
15053504	15053527	19	-	27260157	RKO	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.405955853218488	[]	[]	2	hSpCas9	negative selection	2872404
15053729	15053752	19	+	27260157	RKO	viability	CCAGCAATTCCAGGAAGAGCTGG	CASP14	ENSG00000105141	0.585007461589851	[]	[]	3	hSpCas9	negative selection	2877033
15053786	15053809	19	+	27260157	SF268	viability	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.482150631823206	[]	[]	7	hSpCas9	negative selection	2885987
15053559	15053582	19	-	27260157	SF268	viability	ACATGTGTTCCAGAGCATCCAGG	CASP14	ENSG00000105141	1.16190215223318	[]	[]	9	hSpCas9	negative selection	2885994
15052251	15052274	19	+	27260157	SF268	viability	AATGAGCAATCCGCGGTCTTTGG	CASP14	ENSG00000105141	0.583927835239145	[]	[]	8	hSpCas9	negative selection	2886481
15052261	15052284	19	-	27260157	SF268	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.269013816806631	[]	[]	4	hSpCas9	negative selection	2888680
15053776	15053799	19	-	27260157	SF268	viability	ACAACTGACGGGATCTTCCCGGG	CASP14	ENSG00000105141	-0.243809792552531	[]	[]	-2	hSpCas9	negative selection	2892172
15052257	15052280	19	+	27260157	SF268	viability	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.623602239344282	[]	[]	-5	hSpCas9	negative selection	2908885
15053531	15053554	19	-	27260157	SF268	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.462886107188954	[]	[]	-4	hSpCas9	negative selection	2912303
15053513	15053536	19	-	27260157	SF268	viability	TTTGGTGACACACAGTATTAGGG	CASP14	ENSG00000105141	-1.22294526223222	[]	[]	-7	hSpCas9	negative selection	2916685
15053758	15053781	19	+	27260157	SF268	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	-0.537212569432804	[]	[]	-4	hSpCas9	negative selection	2919273
15053519	15053542	19	+	27260157	SF268	viability	TACTGTGTGTCACCAAAGCCCGG	CASP14	ENSG00000105141	1.31116576610641	[]	[]	9	hSpCas9	negative selection	2919356
15053478	15053501	19	-	27260157	SF268	viability	CTGACATATCATATTTCTCCTGG	CASP14	ENSG00000105141	-0.35208852658259	[]	[]	-3	hSpCas9	negative selection	2922982
15053759	15053782	19	-	27260157	SF268	viability	CCCGGGAATCGATGGCCTGCTGG	CASP14	ENSG00000105141	0.701603628437624	[]	[]	8	hSpCas9	negative selection	2923498
15053524	15053547	19	+	27260157	SF268	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.175867172084343	[]	[]	0	hSpCas9	negative selection	2925562
15053490	15053513	19	+	27260157	SF268	viability	TGATATGTCAGGTGCCCGCCTGG	CASP14	ENSG00000105141	-0.138586572897147	[]	[]	-1	hSpCas9	negative selection	2945285
15053504	15053527	19	-	27260157	SF268	viability	ACACAGTATTAGGGCCAGGCGGG	CASP14	ENSG00000105141	0.40985506291759	[]	[]	4	hSpCas9	negative selection	2948534
15053729	15053752	19	+	27260157	SF268	viability	CCAGCAATTCCAGGAAGAGCTGG	CASP14	ENSG00000105141	0.940847064336248	[]	[]	9	hSpCas9	negative selection	2953163
15052245	15052268	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.03492143610276682	[4,4]	[3,3]	0	hSpCas9	positive selection	2976403
15053745	15053768	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	0.3600740530839964	[2,2]	[1,3]	7	hSpCas9	positive selection	2976404
15053505	15053528	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	-0.004736587408382592	[4,3]	[3,2]	0	hSpCas9	positive selection	2976405
15052261	15052284	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.5619256296468439	[3,3]	[0,3]	-7	hSpCas9	positive selection	2976406
15052245	15052268	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.006998002892737831	[4,4]	[4,1]	0	hSpCas9	positive selection	3044261
15053745	15053768	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	0.02370901293382016	[2,2]	[4,0]	0	hSpCas9	positive selection	3044262
15053505	15053528	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	-0.45766442860320194	[4,4]	[2,0]	-6	hSpCas9	positive selection	3044263
15052261	15052284	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.13152852685426428	[3,3]	[3,2]	2	hSpCas9	positive selection	3044264
15053777	15053800		-	24336571	A375	resistance to PLX after 7 days	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	0.20472611891815423	[11,11]	[14,12]	6	hSpCas9	positive selection	3160716
15053621	15053644		-	24336571	A375	resistance to PLX after 7 days	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.08656461012516126	[8,6]	[8,6]	-3	hSpCas9	positive selection	3160717
15053786	15053809		+	24336571	A375	resistance to PLX after 7 days	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	-0.11352867427011759	[42,40]	[41,34]	-4	hSpCas9	positive selection	3160718
15053531	15053554		-	24336571	A375	resistance to PLX after 7 days	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.014467587795516434	[14,16]	[18,12]	0	hSpCas9	positive selection	3160719
15053777	15053800		-	24336571	A375	resistance to PLX after 14 days	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	-0.05540475389819888	[9,9]	[3,3]	0	hSpCas9	positive selection	3218509
15053621	15053644		-	24336571	A375	resistance to PLX after 14 days	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.14380226861654488	[9,6]	[3,2]	-1	hSpCas9	positive selection	3218510
15053786	15053809		+	24336571	A375	resistance to PLX after 14 days	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.06163479063708066	[40,37]	[17,19]	0	hSpCas9	positive selection	3218511
15053531	15053554		-	24336571	A375	resistance to PLX after 14 days	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.328957183790411	[17,16]	[6,4]	-4	hSpCas9	positive selection	3218512
15053777	15053800		-	24336571	A375	viability after 7 days	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	0.014179473758257767	[12]	[11,11]	0	hSpCas9	negative selection	3276302
15053621	15053644		-	24336571	A375	viability after 7 days	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.055224480944302545	[8]	[8,6]	-1	hSpCas9	negative selection	3276303
15053786	15053809		+	24336571	A375	viability after 7 days	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.931359134890306	[22]	[42,40]	9	hSpCas9	negative selection	3276304
15053531	15053554		-	24336571	A375	viability after 7 days	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.30446708962869395	[13]	[14,16]	4	hSpCas9	negative selection	3276305
15053777	15053800		-	24336571	A375	viability after 14 days	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	-0.31297603260816514	[12]	[9,9]	-4	hSpCas9	negative selection	3334095
15053621	15053644		-	24336571	A375	viability after 14 days	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.010833129113853035	[8]	[9,6]	0	hSpCas9	negative selection	3334096
15053786	15053809		+	24336571	A375	viability after 14 days	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.8579212602474459	[22]	[40,37]	9	hSpCas9	negative selection	3334097
15053531	15053554		-	24336571	A375	viability after 14 days	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.442056349559385	[13]	[17,16]	5	hSpCas9	negative selection	3334098
15053620	15053643	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-1.5260679556595107	[458,421]	[0,0]	-8	hSpCas9	positive selection	3341115
15053531	15053554	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.30769973396095446	[139,106]	[0,0]	1	hSpCas9	positive selection	3341116
15053758	15053781	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.047618020232739894	[151,143]	[0,0]	0	hSpCas9	positive selection	3341117
15055263	15055286	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3360363
15053800	15053823	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	2.257326211445835	[63,63]	[1,1]	8	hSpCas9	positive selection	3360364
15055479	15055502	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.3301387964784912	[576,576]	[2,2]	-2	hSpCas9	positive selection	3360365
15052244	15052267	19	+	26780180	HT29	viability (Avana library 4 designs)	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.740703210798361	[]	[]	3	hSpCas9	negative selection	3412684
15053744	15053767	19	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	1.53328727681526	[]	[]	6	hSpCas9	negative selection	3412685
15053505	15053528	19	-	26780180	HT29	viability (Avana library 4 designs)	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	0.269039100486367	[]	[]	0	hSpCas9	negative selection	3412686
15052261	15052284	19	-	26780180	HT29	viability (Avana library 4 designs)	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.186839756016799	[]	[]	0	hSpCas9	negative selection	3412687
15052261	15052284	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-1.79258418266446	[]	[]	-2	hSpCas9	negative selection	3488274
15052244	15052267	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	1.95725855093112	[]	[]	3	hSpCas9	negative selection	3488275
15053505	15053528	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	4.70087446594404	[]	[]	7	hSpCas9	negative selection	3488276
15053744	15053767	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	3.45470116507806	[]	[]	5	hSpCas9	negative selection	3488277
15053807	15053830	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-1.37874090298798	[]	[]	-2	hSpCas9	negative selection	3488278
15053800	15053823	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.336417740346215	[]	[]	0	hSpCas9	negative selection	3488279
15052261	15052284	19	-	26780180	A375	viability (Avana lentiGuide)	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.017792415536426	[]	[]	0	hSpCas9	negative selection	3596933
15052244	15052267	19	+	26780180	A375	viability (Avana lentiGuide)	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.649222217543672	[]	[]	0	hSpCas9	negative selection	3596934
15053505	15053528	19	-	26780180	A375	viability (Avana lentiGuide)	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	-2.40105067461151	[]	[]	-4	hSpCas9	negative selection	3596935
15053744	15053767	19	+	26780180	A375	viability (Avana lentiGuide)	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	-4.95116861792292	[]	[]	-8	hSpCas9	negative selection	3596936
15053807	15053830	19	+	26780180	A375	viability (Avana lentiGuide)	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-2.8448758899453	[]	[]	-5	hSpCas9	negative selection	3596937
15053800	15053823	19	-	26780180	A375	viability (Avana lentiGuide)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	10.1960993001897	[]	[]	7	hSpCas9	negative selection	3596938
15052261	15052284	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.2779627432947068	[5]	[4,3]	-4	hSpCas9	positive selection	3705592
15052244	15052267	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.11994713729668097	[6]	[6,6]	3	hSpCas9	positive selection	3705593
15053505	15053528	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	0.17936807499095098	[4]	[5,4]	5	hSpCas9	positive selection	3705594
15053744	15053767	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	0.29134057828616294	[4]	[5,5]	8	hSpCas9	positive selection	3705595
15053807	15053830	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.14436867557465127	[4]	[3,4]	-2	hSpCas9	positive selection	3705596
15053800	15053823	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.03518469079778978	[4]	[5,3]	0	hSpCas9	positive selection	3705597
15052261	15052284	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.15190331653283667	[5]	[4,5]	3	hSpCas9	positive selection	3814199
15052244	15052267	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.047273852537034394	[6]	[6,4]	1	hSpCas9	positive selection	3814200
15053505	15053528	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACACAGTATTAGGGCCAGGCGG	CASP14	ENSG00000105141	0.21118553928942696	[5]	[5,5]	5	hSpCas9	positive selection	3814201
15053744	15053767	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCTGGAAAAATTCCAGCAGG	CASP14	ENSG00000105141	0.22270631872726676	[4]	[4,3]	6	hSpCas9	positive selection	3814202
15053807	15053830	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.10768826650686132	[4]	[5,3]	2	hSpCas9	positive selection	3814203
15053800	15053823	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.22888986457421676	[5]	[4,3]	-3	hSpCas9	positive selection	3814204
15053620	15053643	19	-	26780180	A375	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	1.34548547480466	[]	[]	7	hSpCas9	negative selection	3922499
15055263	15055286	19	-	26780180	A375	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	1.51667453706924	[]	[]	8	hSpCas9	negative selection	3922500
15053800	15053823	19	-	26780180	A375	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	1.37196590503185	[]	[]	7	hSpCas9	negative selection	3922501
15053758	15053781	19	+	26780180	A375	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.620311734892864	[]	[]	2	hSpCas9	negative selection	3922502
15055479	15055502	19	-	26780180	A375	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	1.21680435890721	[]	[]	6	hSpCas9	negative selection	3922503
15053531	15053554	19	-	26780180	A375	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	1.24035520194957	[]	[]	6	hSpCas9	negative selection	3922504
15053620	15053643	19	-	26780180	HT29	viability (GeCKOv2 library)	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.341139415464779	[]	[]	0	hSpCas9	negative selection	4030465
15055263	15055286	19	-	26780180	HT29	viability (GeCKOv2 library)	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	1.92380805278812	[]	[]	9	hSpCas9	negative selection	4030466
15053800	15053823	19	-	26780180	HT29	viability (GeCKOv2 library)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	1.59744397897421	[]	[]	8	hSpCas9	negative selection	4030467
15053758	15053781	19	+	26780180	HT29	viability (GeCKOv2 library)	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.972926217289403	[]	[]	4	hSpCas9	negative selection	4030468
15055479	15055502	19	-	26780180	HT29	viability (GeCKOv2 library)	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.15760197269692	[]	[]	-4	hSpCas9	negative selection	4030469
15053531	15053554	19	-	26780180	HT29	viability (GeCKOv2 library)	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	1.0641650906616	[]	[]	5	hSpCas9	negative selection	4030470
15053777	15053800	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	-0.2324827297460758	[3]	[1,1]	-5	hSpCas9	positive selection	4188809
15053621	15053644	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.2928394035776992	[2]	[2,1]	7	hSpCas9	positive selection	4188810
15053786	15053809	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.1199529497485668	[5]	[3,4]	3	hSpCas9	positive selection	4188811
15053531	15053554	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.08772132720138895	[4]	[3,2]	2	hSpCas9	positive selection	4188812
15053777	15053800	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAACTGACGGGATCTTCCCGG	CASP14	ENSG00000105141	0.9008099802648839	[1]	[0,2,4,0]	6	hSpCas9	positive selection	4252831
15053621	15053644	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.3752986382410979	[3]	[1,0,1,0]	-5	hSpCas9	positive selection	4252832
15053786	15053809	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCGTCAGTTGTGCCTTCGTGG	CASP14	ENSG00000105141	0.944001326107495	[4]	[2,0,5,4]	6	hSpCas9	positive selection	4252833
15053531	15053554	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.12221341358156931	[3]	[2,2,1,0]	1	hSpCas9	positive selection	4252834
15053620	15053643	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2258264780373263	[4]	[4,3]	4	hSpCas9	positive selection	4261003
15053531	15053554	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.20012266764565498	[3]	[2,2]	4	hSpCas9	positive selection	4261004
15053758	15053781	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.012323892108496316	[2]	[3,1]	0	hSpCas9	positive selection	4261005
15055263	15055286	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.7070758392911719	[2]	[1,0]	-9	hSpCas9	positive selection	4325281
15053800	15053823	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.44088920503729656	[1]	[1,0]	-7	hSpCas9	positive selection	4325282
15055479	15055502	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.05346952466746446	[4]	[4,2]	1	hSpCas9	positive selection	4325283
15053620	15053642	19	-	27760321	OCIAML3	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.7842157963158034	[1157,958]	[1391,1454]	8	hSpCas9	negative selection	4385789
15053767	15053789	19	-	27760321	OCIAML3	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.6657454100452896	[569,508]	[239,298]	-6	hSpCas9	negative selection	4385790
15053787	15053809	19	-	27760321	OCIAML3	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.07075278586308148	[381,314]	[300,263]	0	hSpCas9	negative selection	4385791
15053808	15053830	19	+	27760321	OCIAML3	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.25576953527037116	[539,535]	[479,534]	3	hSpCas9	negative selection	4385792
15055168	15055190	19	-	27760321	OCIAML3	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.472958834827434	[650,542]	[459,886]	5	hSpCas9	negative selection	4385793
15053620	15053642	19	-	27760321	OCIAML2	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.10133955742819345	[1157,958]	[816,1042]	1	hSpCas9	negative selection	4469252
15053767	15053789	19	-	27760321	OCIAML2	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.34976089751696837	[569,508]	[360,316]	-4	hSpCas9	negative selection	4469253
15053787	15053809	19	-	27760321	OCIAML2	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.11572405226205507	[381,314]	[294,315]	1	hSpCas9	negative selection	4469254
15053808	15053830	19	+	27760321	OCIAML2	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.38623047734501337	[539,535]	[251,441]	-4	hSpCas9	negative selection	4469255
15055168	15055190	19	-	27760321	OCIAML2	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	-0.0702154710390906	[650,542]	[442,477]	-1	hSpCas9	negative selection	4469256
15053620	15053642	19	-	27760321	MV411	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.19323407205792797	[1157,958]	[406,1377]	1	hSpCas9	negative selection	4552715
15053767	15053789	19	-	27760321	MV411	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.6458923916718884	[569,508]	[251,189]	-4	hSpCas9	negative selection	4552716
15053787	15053809	19	-	27760321	MV411	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	1.173053057692231	[381,314]	[731,191]	8	hSpCas9	negative selection	4552717
15053808	15053830	19	+	27760321	MV411	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.47900319946811354	[539,535]	[111,470]	-3	hSpCas9	negative selection	4552718
15055168	15055190	19	-	27760321	MV411	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	-0.24414360030010643	[650,542]	[391,239]	-2	hSpCas9	negative selection	4552719
15053620	15053642	19	-	27760321	HL60	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2691063012181705	[1157,958]	[1131,936]	3	hSpCas9	negative selection	4636178
15053767	15053789	19	-	27760321	HL60	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.5264168584009149	[569,508]	[323,285]	-5	hSpCas9	negative selection	4636179
15053787	15053809	19	-	27760321	HL60	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	-0.35948945588950604	[381,314]	[199,242]	-4	hSpCas9	negative selection	4636180
15053808	15053830	19	+	27760321	HL60	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.03583653240175322	[539,535]	[395,465]	0	hSpCas9	negative selection	4636181
15055168	15055190	19	-	27760321	HL60	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	-0.029253468180725772	[650,542]	[389,566]	0	hSpCas9	negative selection	4636182
15053620	15053642	19	-	27760321	HT1080	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2377334764759933	[958,748]	[193,627]	1	hSpCas9	negative selection	4719641
15053767	15053789	19	-	27760321	HT1080	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.6884070340972517	[508,396]	[100,123]	-3	hSpCas9	negative selection	4719642
15053787	15053809	19	-	27760321	HT1080	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	-0.7893268701435641	[314,245]	[67,60]	-3	hSpCas9	negative selection	4719643
15053808	15053830	19	+	27760321	HT1080	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.600599321398134	[535,417]	[36,221]	-3	hSpCas9	negative selection	4719644
15055168	15055190	19	-	27760321	HT1080	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	1.0887895954544256	[542,423]	[497,312]	6	hSpCas9	negative selection	4719645
15053620	15053642	19	-	27760321	HT29	viability after 7 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2548243362403493	[958,748]	[1279,1704,950]	4	hSpCas9	negative selection	4803104
15053767	15053789	19	-	27760321	HT29	viability after 7 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.9391922500260692	[508,396]	[274,369,262]	-8	hSpCas9	negative selection	4803105
15053787	15053809	19	-	27760321	HT29	viability after 7 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.3678262259354536	[314,245]	[674,208,538]	5	hSpCas9	negative selection	4803106
15053808	15053830	19	+	27760321	HT29	viability after 7 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.6514804993747532	[535,417]	[305,568,286]	-7	hSpCas9	negative selection	4803107
15055168	15055190	19	-	27760321	HT29	viability after 7 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.08137641233450804	[542,423]	[650,716,604]	1	hSpCas9	negative selection	4803108
15053620	15053642	19	-	27760321	HT29	viability after 25 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.3452884677738053	[958,748]	[955,1003,1837]	3	hSpCas9	negative selection	4886567
15053767	15053789	19	-	27760321	HT29	viability after 25 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.6744764557734384	[508,396]	[217,378,388]	-5	hSpCas9	negative selection	4886568
15053787	15053809	19	-	27760321	HT29	viability after 25 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.7045414295091519	[314,245]	[661,378,515]	7	hSpCas9	negative selection	4886569
15053808	15053830	19	+	27760321	HT29	viability after 25 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.022273792978790452	[535,417]	[495,337,805]	0	hSpCas9	negative selection	4886570
15055168	15055190	19	-	27760321	HT29	viability after 25 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.17552169804390544	[542,423]	[465,697,727]	1	hSpCas9	negative selection	4886571
15053620	15053642	19	-	27760321	HT29	viability after 22 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.4316585898911678	[958,748]	[945,1452,1608]	4	hSpCas9	negative selection	4970030
15053767	15053789	19	-	27760321	HT29	viability after 22 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.5313329368882154	[508,396]	[448,340,293]	-5	hSpCas9	negative selection	4970031
15053787	15053809	19	-	27760321	HT29	viability after 22 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.5629711383426018	[314,245]	[598,349,484]	6	hSpCas9	negative selection	4970032
15053808	15053830	19	+	27760321	HT29	viability after 22 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.4293377757671911	[535,417]	[295,471,463]	-4	hSpCas9	negative selection	4970033
15055168	15055190	19	-	27760321	HT29	viability after 22 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.04501681665681778	[542,423]	[416,671,645]	0	hSpCas9	negative selection	4970034
15053620	15053642	19	-	27760321	HT29	viability after 19 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.4871026208782401	[958,748]	[1142,1047,1871]	5	hSpCas9	negative selection	5053493
15053767	15053789	19	-	27760321	HT29	viability after 19 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.5228591065550383	[508,396]	[517,220,358]	-4	hSpCas9	negative selection	5053494
15053787	15053809	19	-	27760321	HT29	viability after 19 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	1.380010254984528	[314,245]	[550,829,1083]	9	hSpCas9	negative selection	5053495
15053808	15053830	19	+	27760321	HT29	viability after 19 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.4984076157096164	[535,417]	[304,358,481]	-4	hSpCas9	negative selection	5053496
15055168	15055190	19	-	27760321	HT29	viability after 19 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.05027275842368667	[542,423]	[624,742,362]	0	hSpCas9	negative selection	5053497
15053620	15053642	19	-	27760321	HT29	viability after 16 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.1832000922024677	[958,748]	[1160,1032,1068]	2	hSpCas9	negative selection	5136956
15053767	15053789	19	-	27760321	HT29	viability after 16 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.19932675398238595	[508,396]	[421,490,407]	-2	hSpCas9	negative selection	5136957
15053787	15053809	19	-	27760321	HT29	viability after 16 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	1.0201448982377024	[314,245]	[723,546,648]	9	hSpCas9	negative selection	5136958
15053808	15053830	19	+	27760321	HT29	viability after 16 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.2843848606121978	[535,417]	[681,149,512]	-3	hSpCas9	negative selection	5136959
15055168	15055190	19	-	27760321	HT29	viability after 16 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.3384491010334801	[542,423]	[719,616,719]	4	hSpCas9	negative selection	5136960
15053620	15053642	19	-	27760321	HT29	viability after 13 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.3487384394728825	[958,748]	[1269,1272,1242]	4	hSpCas9	negative selection	5220419
15053767	15053789	19	-	27760321	HT29	viability after 13 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.632966080987966	[508,396]	[324,461,235]	-6	hSpCas9	negative selection	5220420
15053787	15053809	19	-	27760321	HT29	viability after 13 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.7547122123987986	[314,245]	[485,521,633]	8	hSpCas9	negative selection	5220421
15053808	15053830	19	+	27760321	HT29	viability after 13 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.3876022763777009	[535,417]	[541,310,415]	-4	hSpCas9	negative selection	5220422
15055168	15055190	19	-	27760321	HT29	viability after 13 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.3616827070806094	[542,423]	[885,695,587]	4	hSpCas9	negative selection	5220423
15053620	15053642	19	-	27760321	HT29	viability after 10 days	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2821593686834527	[958,748]	[1197,1345,1345]	4	hSpCas9	negative selection	5303882
15053767	15053789	19	-	27760321	HT29	viability after 10 days	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	-0.4365059256231301	[508,396]	[505,364,381]	-5	hSpCas9	negative selection	5303883
15053787	15053809	19	-	27760321	HT29	viability after 10 days	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.5418376678910017	[314,245]	[501,341,676]	7	hSpCas9	negative selection	5303884
15053808	15053830	19	+	27760321	HT29	viability after 10 days	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.13606231883133046	[535,417]	[609,850,510]	1	hSpCas9	negative selection	5303885
15055168	15055190	19	-	27760321	HT29	viability after 10 days	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	0.025232776382098254	[542,423]	[394,833,619]	0	hSpCas9	negative selection	5303886
15053620	15053642	19	-	27760321	MOLM13	viability	ACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.0793004686921972	[1157,958]	[531,709]	0	hSpCas9	negative selection	5387345
15053767	15053789	19	-	27760321	MOLM13	viability	GGATCTTCCCGGGAATCGATGG	CASP14	ENSG00000105141	0.04713077638875396	[569,508]	[97,497]	0	hSpCas9	negative selection	5387346
15053787	15053809	19	-	27760321	MOLM13	viability	CCACGAAGGCACAACTGACGGG	CASP14	ENSG00000105141	0.7172007876683177	[381,314]	[203,421]	5	hSpCas9	negative selection	5387347
15053808	15053830	19	+	27760321	MOLM13	viability	GTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.5867673059529392	[539,535]	[246,164]	-4	hSpCas9	negative selection	5387348
15055168	15055190	19	-	27760321	MOLM13	viability	TCCACCTACTGTTTCACCGGGG	CASP14	ENSG00000105141	-0.7925530583979216	[650,542]	[157,223]	-5	hSpCas9	negative selection	5387349
15049488	15049511	19	+	27661255	K562	viability	GGCTTCTCAGGAGAAACCCCGGG	CASP14	ENSG00000105141	-0.05452224340342321	[715,762]	[653,494]	-2	dCas9-KRAB	negative selection	5468196
15049918	15049941	19	+	27661255	K562	viability	GAGACAGAGATAATGAAGTCAGG	CASP14	ENSG00000105141	0.1508220782398971	[670,741]	[646,606]	5	dCas9-KRAB	negative selection	5468197
15053620	15053643	19	-	27260156	BXPC3	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2045397626837786	[1405]	[1519,1328,1828,2190]	4	hSpCas9	negative selection	5533463
15053531	15053554	19	-	27260156	BXPC3	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.2290209211419557	[496]	[671,544,549,667]	5	hSpCas9	negative selection	5533464
15053758	15053781	19	+	27260156	BXPC3	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.153569294851259	[458]	[510,443,499,704]	3	hSpCas9	negative selection	5533465
15055263	15055286	19	-	27260156	BXPC3	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.11040970729426502	[361]	[290,294,475,349]	-3	hSpCas9	negative selection	5597741
15053800	15053823	19	-	27260156	BXPC3	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.3600348940842666	[181]	[116,213,101,158]	-7	hSpCas9	negative selection	5597742
15055479	15055502	19	-	27260156	BXPC3	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.007074142868647382	[1690]	[1605,1677,1778,2015]	0	hSpCas9	negative selection	5597743
15053620	15053643	19	-	27260156	A673	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.24383954167951805	[1405]	[2413,1682,1995,1952]	6	hSpCas9	negative selection	5654714
15053531	15053554	19	-	27260156	A673	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.00817197773105481	[496]	[694,476,619,594]	0	hSpCas9	negative selection	5654715
15053758	15053781	19	+	27260156	A673	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.3051088651120632	[458]	[582,734,788,596]	7	hSpCas9	negative selection	5654716
15055263	15055286	19	-	27260156	A673	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.03668662680898649	[361]	[553,420,452,362]	0	hSpCas9	negative selection	5718992
15053800	15053823	19	-	27260156	A673	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.013509412425683154	[181]	[253,175,309,124]	0	hSpCas9	negative selection	5718993
15055479	15055502	19	-	27260156	A673	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.1695631958164685	[1690]	[2515,2220,2063,2363]	4	hSpCas9	negative selection	5718994
15053620	15053643	19	-	27260156	A375	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.16566366250704712	[1405]	[1388,1887,1510,1157]	-2	hSpCas9	negative selection	5775965
15053531	15053554	19	-	27260156	A375	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.013184836686807047	[496]	[737,487,424,629]	0	hSpCas9	negative selection	5775966
15053758	15053781	19	+	27260156	A375	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.2844421008213813	[458]	[936,512,554,593]	4	hSpCas9	negative selection	5775967
15055263	15055286	19	-	27260156	A375	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3321107338488911	[361]	[339,319,297,376]	-5	hSpCas9	negative selection	5840243
15053800	15053823	19	-	27260156	A375	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.02143495945982199	[181]	[117,178,315,217]	0	hSpCas9	negative selection	5840244
15055479	15055502	19	-	27260156	A375	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.17408945632845985	[1690]	[1772,1971,1499,1777]	-3	hSpCas9	negative selection	5840245
15053620	15053643	19	-	27260156	COLO741	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.11907113837292571	[1405]	[2161,2071,1654]	2	hSpCas9	negative selection	5897216
15053531	15053554	19	-	27260156	COLO741	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.1742701602771083	[496]	[993,571,612]	3	hSpCas9	negative selection	5897217
15053758	15053781	19	+	27260156	COLO741	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.0820579660285051	[458]	[633,661,569]	1	hSpCas9	negative selection	5897218
15055263	15055286	19	-	27260156	COLO741	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.1631334694805593	[361]	[528,527,497]	3	hSpCas9	negative selection	5961494
15053800	15053823	19	-	27260156	COLO741	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.22499757713914192	[181]	[162,224,204]	-5	hSpCas9	negative selection	5961495
15055479	15055502	19	-	27260156	COLO741	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.1374923514751023	[1690]	[2364,2219,2526]	3	hSpCas9	negative selection	5961496
15053620	15053643	19	-	27260156	CAL120	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.4254628988571654	[1405]	[2515,2026,2526]	6	hSpCas9	negative selection	6018467
15053531	15053554	19	-	27260156	CAL120	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.39043954487247134	[496]	[937,766,746]	6	hSpCas9	negative selection	6018468
15053758	15053781	19	+	27260156	CAL120	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.23086749622387964	[458]	[1002,461,596]	3	hSpCas9	negative selection	6018469
15055263	15055286	19	-	27260156	CAL120	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.024547390218801424	[361]	[414,499,452]	0	hSpCas9	negative selection	6082745
15053800	15053823	19	-	27260156	CAL120	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.3899485385320758	[181]	[473,210,232]	6	hSpCas9	negative selection	6082746
15055479	15055502	19	-	27260156	CAL120	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.2179402816534841	[1690]	[2973,2142,2305]	3	hSpCas9	negative selection	6082747
15053620	15053643	19	-	27260156	CADOES1	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.023688681883290652	[1405]	[1362,1250,1249,1280]	0	hSpCas9	negative selection	6139718
15053531	15053554	19	-	27260156	CADOES1	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.0631299571289738	[496]	[447,526,367,592]	1	hSpCas9	negative selection	6139719
15053758	15053781	19	+	27260156	CADOES1	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.4315261148236294	[458]	[643,485,458,718]	7	hSpCas9	negative selection	6139720
15055263	15055286	19	-	27260156	CADOES1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.20440228061061733	[361]	[321,569,253,406]	3	hSpCas9	negative selection	6203996
15053800	15053823	19	-	27260156	CADOES1	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.5494417988420319	[181]	[93,72,194,99]	-7	hSpCas9	negative selection	6203997
15055479	15055502	19	-	27260156	CADOES1	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.18898451668431138	[1690]	[2087,1711,1641,1725]	3	hSpCas9	negative selection	6203998
15053620	15053643	19	-	27260156	EWS502	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.10002617840852301	[1405]	[1479,1801,1579,1515]	1	hSpCas9	negative selection	6260969
15053531	15053554	19	-	27260156	EWS502	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.011262815777715485	[496]	[433,530,609,559]	0	hSpCas9	negative selection	6260970
15053758	15053781	19	+	27260156	EWS502	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.4168525643565762	[458]	[620,635,597,748]	7	hSpCas9	negative selection	6260971
15055263	15055286	19	-	27260156	EWS502	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.107135461028035	[361]	[355,349,245,477]	-2	hSpCas9	negative selection	6325247
15053800	15053823	19	-	27260156	EWS502	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.3313823477471498	[181]	[133,104,233,143]	-5	hSpCas9	negative selection	6325248
15055479	15055502	19	-	27260156	EWS502	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.2978005239994803	[1690]	[2015,2146,2102,2582]	5	hSpCas9	negative selection	6325249
15053620	15053643	19	-	27260156	EW8	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.05274615796254478	[1405]	[1153,1125,980,1155]	-1	hSpCas9	negative selection	6382220
15053531	15053554	19	-	27260156	EW8	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.042737710387476466	[496]	[375,510,304,480]	0	hSpCas9	negative selection	6382221
15053758	15053781	19	+	27260156	EW8	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.2439870957558745	[458]	[433,420,529,359]	4	hSpCas9	negative selection	6382222
15055263	15055286	19	-	27260156	EW8	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.18267576786647624	[361]	[343,226,250,522]	3	hSpCas9	negative selection	6446498
15053800	15053823	19	-	27260156	EW8	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.31416455197355164	[181]	[229,92,61,110]	-5	hSpCas9	negative selection	6446499
15055479	15055502	19	-	27260156	EW8	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.09805326362846922	[1690]	[1561,1325,1547,1422]	1	hSpCas9	negative selection	6446500
15053620	15053643	19	-	27260156	CORL105	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.009284856134591957	[1405]	[1461,1506,1889,1798]	0	hSpCas9	negative selection	6503471
15053531	15053554	19	-	27260156	CORL105	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.07552316865602542	[496]	[539,593,808,537]	1	hSpCas9	negative selection	6503472
15053758	15053781	19	+	27260156	CORL105	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.3813005894912587	[458]	[743,697,686,669]	7	hSpCas9	negative selection	6503473
15055263	15055286	19	-	27260156	CORL105	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.267840704712185	[361]	[353,294,415,353]	-5	hSpCas9	negative selection	6567749
15053800	15053823	19	-	27260156	CORL105	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.30115543382307464	[181]	[121,359,286,277]	5	hSpCas9	negative selection	6567750
15055479	15055502	19	-	27260156	CORL105	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.21256434319768136	[1690]	[1479,1912,1713,1714]	-4	hSpCas9	negative selection	6567751
15053620	15053643	19	-	27260156	HS294T	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2894003033055135	[1405]	[651,556,687,782]	4	hSpCas9	negative selection	6624722
15053531	15053554	19	-	27260156	HS294T	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.5169322579048363	[496]	[108,157,138,131]	-6	hSpCas9	negative selection	6624723
15053758	15053781	19	+	27260156	HS294T	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	1.0185478765291476	[458]	[243,512,230,473]	9	hSpCas9	negative selection	6624724
15055263	15055286	19	-	27260156	HS294T	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.6226387214968201	[361]	[82,93,95,90]	-7	hSpCas9	negative selection	6689000
15053800	15053823	19	-	27260156	HS294T	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.9484338106706379	[181]	[55,180,225,75]	9	hSpCas9	negative selection	6689001
15055479	15055502	19	-	27260156	HS294T	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.13537887873898358	[1690]	[702,570,536,550]	-2	hSpCas9	negative selection	6689002
15053620	15053643	19	-	27260156	HCC44	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2877478335406869	[1405]	[2262,1393,2372,1901]	5	hSpCas9	negative selection	6745973
15053531	15053554	19	-	27260156	HCC44	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.3319947161917618	[496]	[688,557,1002,646]	5	hSpCas9	negative selection	6745974
15053758	15053781	19	+	27260156	HCC44	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.19480286029262317	[458]	[743,345,667,672]	3	hSpCas9	negative selection	6745975
15055263	15055286	19	-	27260156	HCC44	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.1301246211701364	[361]	[382,354,494,566]	2	hSpCas9	negative selection	6810251
15053800	15053823	19	-	27260156	HCC44	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.0542292288854096	[181]	[148,262,124,226]	-1	hSpCas9	negative selection	6810252
15055479	15055502	19	-	27260156	HCC44	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.1784342051034562	[1690]	[2572,1958,2314,1893]	3	hSpCas9	negative selection	6810253
15053620	15053643	19	-	27260156	G402	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.0008270635509606272	[1405]	[1732,2140,2149,902]	0	hSpCas9	negative selection	6867224
15053531	15053554	19	-	27260156	G402	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.08769360413325501	[496]	[1185,487,571,409]	1	hSpCas9	negative selection	6867225
15053758	15053781	19	+	27260156	G402	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.21772540904687257	[458]	[797,500,576,734]	2	hSpCas9	negative selection	6867226
15055263	15055286	19	-	27260156	G402	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.43750692470979047	[361]	[213,329,471,273]	-5	hSpCas9	negative selection	6931502
15053800	15053823	19	-	27260156	G402	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-1.287946245350314	[181]	[35,119,84,114]	-8	hSpCas9	negative selection	6931503
15055479	15055502	19	-	27260156	G402	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.06541534956545458	[1690]	[2453,2634,1658,1959]	0	hSpCas9	negative selection	6931504
15053620	15053643	19	-	27260156	L33	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.43583587763176523	[1405]	[1769,775,1203,2029]	8	hSpCas9	negative selection	6988475
15053531	15053554	19	-	27260156	L33	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.038680098317644525	[496]	[448,233,273,479]	-1	hSpCas9	negative selection	6988476
15053758	15053781	19	+	27260156	L33	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.31051693868570507	[458]	[531,217,400,575]	6	hSpCas9	negative selection	6988477
15055263	15055286	19	-	27260156	L33	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3411158113333498	[361]	[260,131,190,256]	-7	hSpCas9	negative selection	7052753
15053800	15053823	19	-	27260156	L33	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.16775844636389436	[181]	[118,98,136,240]	3	hSpCas9	negative selection	7052754
15055479	15055502	19	-	27260156	L33	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.007142872261985067	[1690]	[1743,645,1158,1632]	0	hSpCas9	negative selection	7052755
15053620	15053643	19	-	27260156	K562	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.22659346241656975	[1405]	[1457,2123,1418,929]	3	hSpCas9	negative selection	7109726
15053531	15053554	19	-	27260156	K562	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.1173693315446389	[496]	[532,516,538,344]	1	hSpCas9	negative selection	7109727
15053758	15053781	19	+	27260156	K562	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.4899265371814194	[458]	[496,641,616,531]	6	hSpCas9	negative selection	7109728
15055263	15055286	19	-	27260156	K562	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.08289645074373447	[361]	[305,522,263,148]	-1	hSpCas9	negative selection	7174004
15053800	15053823	19	-	27260156	K562	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.5976856684770115	[181]	[117,60,129,114]	-6	hSpCas9	negative selection	7174005
15055479	15055502	19	-	27260156	K562	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.27789923046971543	[1690]	[1793,2090,1444,1937]	3	hSpCas9	negative selection	7174006
15053620	15053643	19	-	27260156	HT29	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.007823621747388598	[1405]	[2223,1589,1741,1375]	0	hSpCas9	negative selection	7230977
15053531	15053554	19	-	27260156	HT29	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.0783932948161923	[496]	[746,774,585,478]	1	hSpCas9	negative selection	7230978
15053758	15053781	19	+	27260156	HT29	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.19246958184027807	[458]	[747,645,514,644]	4	hSpCas9	negative selection	7230979
15055263	15055286	19	-	27260156	HT29	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.06081740476797903	[361]	[436,445,578,377]	1	hSpCas9	negative selection	7295255
15053800	15053823	19	-	27260156	HT29	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.010815143893889267	[181]	[153,316,173,244]	0	hSpCas9	negative selection	7295256
15055479	15055502	19	-	27260156	HT29	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.31976341334421887	[1690]	[2700,2985,2357,2280]	6	hSpCas9	negative selection	7295257
15053620	15053643	19	-	27260156	MHHES1	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.0722603794130865	[1405]	[2026,1774,1764,1215]	1	hSpCas9	negative selection	7352228
15053531	15053554	19	-	27260156	MHHES1	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.2856611532833223	[496]	[1028,764,653,385]	5	hSpCas9	negative selection	7352229
15053758	15053781	19	+	27260156	MHHES1	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.3569295945701652	[458]	[963,653,605,485]	6	hSpCas9	negative selection	7352230
15055263	15055286	19	-	27260156	MHHES1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.19106120268239712	[361]	[301,373,445,305]	-4	hSpCas9	negative selection	7416506
15053800	15053823	19	-	27260156	MHHES1	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.3158943739689788	[181]	[92,168,270,123]	-5	hSpCas9	negative selection	7416507
15055479	15055502	19	-	27260156	MHHES1	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.028272361706747073	[1690]	[2622,2263,1740,1349]	0	hSpCas9	negative selection	7416508
15053620	15053643	19	-	27260156	MEWO	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2648215998507437	[1405]	[1725,1407,1635]	6	hSpCas9	negative selection	7473479
15053531	15053554	19	-	27260156	MEWO	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.3320693033305621	[496]	[596,602,557]	7	hSpCas9	negative selection	7473480
15053758	15053781	19	+	27260156	MEWO	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.07695759824436005	[458]	[545,407,422]	1	hSpCas9	negative selection	7473481
15055263	15055286	19	-	27260156	MEWO	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.15464724510189476	[361]	[402,363,368]	3	hSpCas9	negative selection	7537757
15053800	15053823	19	-	27260156	MEWO	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.145354857329127	[181]	[184,120,161]	-3	hSpCas9	negative selection	7537758
15055479	15055502	19	-	27260156	MEWO	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.2997327957738487	[1690]	[2279,1961,1663]	6	hSpCas9	negative selection	7537759
15053620	15053643	19	-	27260156	LNCAPCLONEFGC	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.2874199849700121	[1405]	[1516,1308,1853,1597]	4	hSpCas9	negative selection	7594730
15053531	15053554	19	-	27260156	LNCAPCLONEFGC	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.04404009109639608	[496]	[505,479,394,354]	0	hSpCas9	negative selection	7594731
15053758	15053781	19	+	27260156	LNCAPCLONEFGC	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.5722695786891808	[458]	[640,614,609,604]	8	hSpCas9	negative selection	7594732
15055263	15055286	19	-	27260156	LNCAPCLONEFGC	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.14582929684184065	[361]	[303,194,370,332]	-2	hSpCas9	negative selection	7659008
15053800	15053823	19	-	27260156	LNCAPCLONEFGC	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.0011812214337210136	[181]	[154,105,218,191]	0	hSpCas9	negative selection	7659009
15055479	15055502	19	-	27260156	LNCAPCLONEFGC	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.11211362283233761	[1690]	[1740,1472,1866,1581]	1	hSpCas9	negative selection	7659010
15053620	15053643	19	-	27260156	PANC0327	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.0741284019428401	[1405]	[1353,1345,1277,1279]	1	hSpCas9	negative selection	7715981
15053531	15053554	19	-	27260156	PANC0327	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.2395578751295857	[496]	[523,552,547,455]	3	hSpCas9	negative selection	7715982
15053758	15053781	19	+	27260156	PANC0327	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.5554126455394387	[458]	[511,398,974,529]	7	hSpCas9	negative selection	7715983
15055263	15055286	19	-	27260156	PANC0327	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.033351024231551396	[361]	[270,385,265,380]	0	hSpCas9	negative selection	7780259
15053800	15053823	19	-	27260156	PANC0327	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.12937428051425814	[181]	[182,84,86,246]	-2	hSpCas9	negative selection	7780260
15055479	15055502	19	-	27260156	PANC0327	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.24969543579411524	[1690]	[1707,982,1288,1145]	-4	hSpCas9	negative selection	7780261
15053620	15053643	19	-	27260156	NCIH2009	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.53010431572258	[1405]	[3373,2416,2827]	7	hSpCas9	negative selection	7837232
15053531	15053554	19	-	27260156	NCIH2009	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.1628682146772451	[496]	[729,532,619]	-2	hSpCas9	negative selection	7837233
15053758	15053781	19	+	27260156	NCIH2009	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.7760450493043994	[458]	[1231,1103,982]	9	hSpCas9	negative selection	7837234
15055263	15055286	19	-	27260156	NCIH2009	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3274527594204356	[361]	[581,286,376]	-4	hSpCas9	negative selection	7901510
15053800	15053823	19	-	27260156	NCIH2009	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-1.0473194853555565	[181]	[157,112,104]	-8	hSpCas9	negative selection	7901511
15055479	15055502	19	-	27260156	NCIH2009	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.04039285219087563	[1690]	[2344,2109,2445]	0	hSpCas9	negative selection	7901512
15053620	15053643	19	-	27260156	NCIH1373	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.30296583338326055	[1405]	[1532,1355,1070,307]	-3	hSpCas9	negative selection	7958483
15053531	15053554	19	-	27260156	NCIH1373	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.31189362434840723	[496]	[539,413,411,116]	-3	hSpCas9	negative selection	7958484
15053758	15053781	19	+	27260156	NCIH1373	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.9811654998039695	[458]	[1491,722,919,270]	8	hSpCas9	negative selection	7958485
15055263	15055286	19	-	27260156	NCIH1373	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.7264733578550799	[361]	[303,124,267,80]	-6	hSpCas9	negative selection	8022761
15053800	15053823	19	-	27260156	NCIH1373	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.6277195872596975	[181]	[200,146,140,10]	-6	hSpCas9	negative selection	8022762
15055479	15055502	19	-	27260156	NCIH1373	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.5698839590181592	[1690]	[1524,873,1339,381]	-5	hSpCas9	negative selection	8022763
15053620	15053643	19	-	27260156	PATU8902	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.339698095347728	[1405]	[2234,1881,860,1344]	-3	hSpCas9	negative selection	8079734
15053531	15053554	19	-	27260156	PATU8902	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-1.4108426337360533	[496]	[200,283,312,223]	-8	hSpCas9	negative selection	8079735
15053758	15053781	19	+	27260156	PATU8902	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.4565485173255818	[458]	[941,1053,611,973]	5	hSpCas9	negative selection	8079736
15055263	15055286	19	-	27260156	PATU8902	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3599546739973938	[361]	[429,351,349,453]	-4	hSpCas9	negative selection	8144012
15053800	15053823	19	-	27260156	PATU8902	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.23390828899913463	[181]	[149,364,134,234]	-2	hSpCas9	negative selection	8144013
15055479	15055502	19	-	27260156	PATU8902	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.03428819286520768	[1690]	[1960,2180,2057,3148]	0	hSpCas9	negative selection	8144014
15053620	15053643	19	-	27260156	PANC1	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.22257534153016612	[1405]	[1135,1557,1670,1303]	3	hSpCas9	negative selection	8200985
15053531	15053554	19	-	27260156	PANC1	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.12248776649141896	[496]	[491,467,334,295]	-2	hSpCas9	negative selection	8200986
15053758	15053781	19	+	27260156	PANC1	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.6151489018171776	[458]	[537,596,654,613]	8	hSpCas9	negative selection	8200987
15055263	15055286	19	-	27260156	PANC1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.4383111790826657	[361]	[224,388,182,160]	-6	hSpCas9	negative selection	8265263
15053800	15053823	19	-	27260156	PANC1	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.4738779616557761	[181]	[229,131,225,252]	7	hSpCas9	negative selection	8265264
15055479	15055502	19	-	27260156	PANC1	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.013645225120393123	[1690]	[1556,1745,1363,1168]	0	hSpCas9	negative selection	8265265
15053620	15053643	19	-	27260156	PANC0813	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.36628806595985597	[1405]	[2319,1868,1898,2423]	6	hSpCas9	negative selection	8322236
15053531	15053554	19	-	27260156	PANC0813	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.12465928390108395	[496]	[536,648,461,494]	-2	hSpCas9	negative selection	8322237
15053758	15053781	19	+	27260156	PANC0813	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.517633050199611	[458]	[682,813,875,708]	8	hSpCas9	negative selection	8322238
15055263	15055286	19	-	27260156	PANC0813	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.07545269342857075	[361]	[336,333,760,355]	1	hSpCas9	negative selection	8386514
15053800	15053823	19	-	27260156	PANC0813	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-1.1814635227507266	[181]	[74,103,133,63]	-9	hSpCas9	negative selection	8386515
15055479	15055502	19	-	27260156	PANC0813	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.11052885772240795	[1690]	[2005,2427,2366,1781]	1	hSpCas9	negative selection	8386516
15053620	15053643	19	-	27260156	RDES	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.040145155654954134	[1405]	[1222,1514,1480,2197]	0	hSpCas9	negative selection	8443487
15053531	15053554	19	-	27260156	RDES	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.14506411500000532	[496]	[496,683,592,779]	2	hSpCas9	negative selection	8443488
15053758	15053781	19	+	27260156	RDES	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.5925788085876057	[458]	[748,650,632,1205]	8	hSpCas9	negative selection	8443489
15055263	15055286	19	-	27260156	RDES	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.09667434962564403	[361]	[369,379,450,614]	1	hSpCas9	negative selection	8507765
15053800	15053823	19	-	27260156	RDES	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.3002462909703443	[181]	[109,205,145,230]	-5	hSpCas9	negative selection	8507766
15055479	15055502	19	-	27260156	RDES	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.11992959229893696	[1690]	[1735,1935,2376,2508]	2	hSpCas9	negative selection	8507767
15053620	15053643	19	-	27260156	PC3	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.288804933371972	[1405]	[1032,1803,2842,1739]	6	hSpCas9	negative selection	8564738
15053531	15053554	19	-	27260156	PC3	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.039574928993190615	[496]	[360,448,827,421]	-1	hSpCas9	negative selection	8564739
15053758	15053781	19	+	27260156	PC3	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.0756103413746897	[458]	[289,457,822,532]	1	hSpCas9	negative selection	8564740
15055263	15055286	19	-	27260156	PC3	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.019000705918320204	[361]	[251,428,439,336]	0	hSpCas9	negative selection	8629016
15053800	15053823	19	-	27260156	PC3	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.5904862135848801	[181]	[105,98,222,83]	-8	hSpCas9	negative selection	8629017
15055479	15055502	19	-	27260156	PC3	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.04726861138069416	[1690]	[1183,1366,2978,1547]	-1	hSpCas9	negative selection	8629018
15053620	15053643	19	-	27260156	PATU8988T	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.36716641758762436	[1405]	[1727,1860,1867,1543]	6	hSpCas9	negative selection	8685989
15053531	15053554	19	-	27260156	PATU8988T	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.09954785511373383	[496]	[379,601,379,445]	-2	hSpCas9	negative selection	8685990
15053758	15053781	19	+	27260156	PATU8988T	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.7196757181484607	[458]	[565,752,604,1024]	9	hSpCas9	negative selection	8685991
15055263	15055286	19	-	27260156	PATU8988T	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.37290199946560076	[361]	[193,343,300,245]	-6	hSpCas9	negative selection	8750267
15053800	15053823	19	-	27260156	PATU8988T	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.22038804387668076	[181]	[94,195,153,163]	-4	hSpCas9	negative selection	8750268
15055479	15055502	19	-	27260156	PATU8988T	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.05941194334362754	[1690]	[1666,1470,1362,1781]	-1	hSpCas9	negative selection	8750269
15053620	15053643	19	-	27260156	T47D	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.20586142588607803	[1405]	[1945,1741,1900,1982]	4	hSpCas9	negative selection	8807240
15053531	15053554	19	-	27260156	T47D	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	-0.09909636897660795	[496]	[654,521,480,505]	-2	hSpCas9	negative selection	8807241
15053758	15053781	19	+	27260156	T47D	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.5263273967617065	[458]	[730,771,753,824]	9	hSpCas9	negative selection	8807242
15055263	15055286	19	-	27260156	T47D	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.012289624612392469	[361]	[456,341,435,474]	0	hSpCas9	negative selection	8871518
15053800	15053823	19	-	27260156	T47D	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.18137350191321566	[181]	[203,192,158,191]	-4	hSpCas9	negative selection	8871519
15055479	15055502	19	-	27260156	T47D	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.21407749835258105	[1690]	[2502,1973,2298,2394]	4	hSpCas9	negative selection	8871520
15053620	15053643	19	-	27260156	SU8686	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.04498458260345717	[1405]	[1541,1078,1442,1765]	0	hSpCas9	negative selection	8928491
15053531	15053554	19	-	27260156	SU8686	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.22955142121372663	[496]	[429,494,605,847]	4	hSpCas9	negative selection	8928492
15053758	15053781	19	+	27260156	SU8686	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.5824141929293818	[458]	[650,573,737,794]	8	hSpCas9	negative selection	8928493
15055263	15055286	19	-	27260156	SU8686	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.05503501384894155	[361]	[405,276,243,471]	-1	hSpCas9	negative selection	8992769
15053800	15053823	19	-	27260156	SU8686	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.5456944189581581	[181]	[121,141,88,139]	-7	hSpCas9	negative selection	8992770
15055479	15055502	19	-	27260156	SU8686	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	-0.11338507200260683	[1690]	[1506,1410,1418,1931]	-2	hSpCas9	negative selection	8992771
15053620	15053643	19	-	27260156	SKES1	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.19355795103599638	[1405]	[2024,1718,1532,1238]	4	hSpCas9	negative selection	9049742
15053531	15053554	19	-	27260156	SKES1	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.14480311103943405	[496]	[593,564,604,442]	3	hSpCas9	negative selection	9049743
15053758	15053781	19	+	27260156	SKES1	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.13206551012494236	[458]	[558,513,447,491]	3	hSpCas9	negative selection	9049744
15055263	15055286	19	-	27260156	SKES1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.1220723554340084	[361]	[440,332,272,296]	-3	hSpCas9	negative selection	9114020
15053800	15053823	19	-	27260156	SKES1	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.2534468298826422	[181]	[152,205,167,93]	-5	hSpCas9	negative selection	9114021
15055479	15055502	19	-	27260156	SKES1	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.09025063580839143	[1690]	[2154,1960,1652,1501]	2	hSpCas9	negative selection	9114022
15053620	15053643	19	-	27260156	TOV112D	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.10036112254341045	[1405]	[1514,1073,1233,1384]	-2	hSpCas9	negative selection	9170993
15053531	15053554	19	-	27260156	TOV112D	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.09659011242446384	[496]	[507,649,536,461]	2	hSpCas9	negative selection	9170994
15053758	15053781	19	+	27260156	TOV112D	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.39176644846213765	[458]	[487,825,694,451]	7	hSpCas9	negative selection	9170995
15055263	15055286	19	-	27260156	TOV112D	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.07120459284605146	[361]	[312,531,300,278]	-1	hSpCas9	negative selection	9235271
15053800	15053823	19	-	27260156	TOV112D	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	0.26100058543965443	[181]	[255,232,204,186]	5	hSpCas9	negative selection	9235272
15055479	15055502	19	-	27260156	TOV112D	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.04164633890087743	[1690]	[1909,1857,1707,1541]	0	hSpCas9	negative selection	9235273
15053620	15053643	19	-	27260156	TC71	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	0.22441645228558604	[1405]	[1909,1651,1659,1824]	5	hSpCas9	negative selection	9292244
15053531	15053554	19	-	27260156	TC71	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.1905322244756698	[496]	[501,610,608,718]	5	hSpCas9	negative selection	9292245
15053758	15053781	19	+	27260156	TC71	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.20811286480985158	[458]	[578,450,589,657]	5	hSpCas9	negative selection	9292246
15055263	15055286	19	-	27260156	TC71	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.05904389599900317	[361]	[398,387,458,366]	1	hSpCas9	negative selection	9356522
15053800	15053823	19	-	27260156	TC71	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.30396599648560807	[181]	[128,169,186,144]	-7	hSpCas9	negative selection	9356523
15055479	15055502	19	-	27260156	TC71	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.05486813582928152	[1690]	[1665,2028,1706,2156]	1	hSpCas9	negative selection	9356524
15053620	15053643	19	-	27260156	TC32	viability	CACCCCAATACCTCGGCAGTGGG	CASP14	ENSG00000105141	-0.02204890570185425	[1405]	[1301,870,1756,1448]	0	hSpCas9	negative selection	9413495
15053531	15053554	19	-	27260156	TC32	viability	TTCGGAACCTTCCCGGGCTTTGG	CASP14	ENSG00000105141	0.1574250737116641	[496]	[409,403,674,656]	3	hSpCas9	negative selection	9413496
15053758	15053781	19	+	27260156	TC32	viability	TCCAGCAGGCCATCGATTCCCGG	CASP14	ENSG00000105141	0.49955913764800997	[458]	[751,409,868,464]	8	hSpCas9	negative selection	9413497
15055263	15055286	19	-	27260156	TC32	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.12752329212857927	[361]	[270,470,390,301]	2	hSpCas9	negative selection	9477773
15053800	15053823	19	-	27260156	TC32	viability	GTGAGCCATGAGTACCACGAAGG	CASP14	ENSG00000105141	-0.1615024717972977	[181]	[139,114,136,227]	-3	hSpCas9	negative selection	9477774
15055479	15055502	19	-	27260156	TC32	viability	TCTTCGTGAACACATCCACCAGG	CASP14	ENSG00000105141	0.1150568848735325	[1690]	[1731,1329,2104,1830]	2	hSpCas9	negative selection	9477775
15052257	15052280	19	+	27869803	HPAFII	viability after 27 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.027719738153482387	[103]	[57,49,NaN]	0	hSpCas9	negative selection	9566027
15053806	15053829	19	+	27869803	HPAFII	viability after 27 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-1.3230820267891208	[227]	[18,71,NaN]	-7	hSpCas9	negative selection	9566028
15053937	15053960	19	+	27869803	HPAFII	viability after 27 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.5808066365078683	[196]	[197,118,NaN]	5	hSpCas9	negative selection	9566029
15055438	15055461	19	+	27869803	HPAFII	viability after 27 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.32743839788620344	[455]	[482,148,NaN]	2	hSpCas9	negative selection	9566030
15055461	15055484	19	+	27869803	HPAFII	viability after 27 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.37625638210730694	[394]	[268,269,NaN]	3	hSpCas9	negative selection	9566031
15056061	15056084	19	-	27869803	HPAFII	viability after 27 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.011871838994102435	[206]	[112,106,NaN]	0	hSpCas9	negative selection	9566032
15052257	15052280	19	+	27869803	HPAFII	viability after 15 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.3001338184487976	[103]	[173,114,NaN]	3	hSpCas9	negative selection	9648476
15053806	15053829	19	+	27869803	HPAFII	viability after 15 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.5174177187815425	[227]	[230,133,NaN]	-5	hSpCas9	negative selection	9648477
15053937	15053960	19	+	27869803	HPAFII	viability after 15 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-0.09408424947964433	[196]	[251,164,NaN]	-1	hSpCas9	negative selection	9648478
15055438	15055461	19	+	27869803	HPAFII	viability after 15 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.07253902285846392	[455]	[843,310,NaN]	0	hSpCas9	negative selection	9648479
15055461	15055484	19	+	27869803	HPAFII	viability after 15 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.2640054355928293	[394]	[666,411,NaN]	3	hSpCas9	negative selection	9648480
15056061	15056084	19	-	27869803	HPAFII	viability after 15 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.18213311542144514	[206]	[125,330,NaN]	2	hSpCas9	negative selection	9648481
15052257	15052280	19	+	27869803	ASPC1	viability after 36 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.2732039414923506	[285]	[283,103,17]	2	hSpCas9	negative selection	9730925
15053806	15053829	19	+	27869803	ASPC1	viability after 36 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.44666181548874345	[497]	[74,172,126]	-4	hSpCas9	negative selection	9730926
15053937	15053960	19	+	27869803	ASPC1	viability after 36 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	-0.6156775227798423	[591]	[278,65,86]	-6	hSpCas9	negative selection	9730927
15055438	15055461	19	+	27869803	ASPC1	viability after 36 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.2535904991136746	[1132]	[243,608,516]	2	hSpCas9	negative selection	9730928
15055461	15055484	19	+	27869803	ASPC1	viability after 36 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.6352007285817005	[846]	[158,821,376]	6	hSpCas9	negative selection	9730929
15056061	15056084	19	-	27869803	ASPC1	viability after 36 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.2830922911135325	[572]	[247,97,352]	3	hSpCas9	negative selection	9730930
15052257	15052280	19	+	27869803	PATU8988S	viability after 35 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.0781166450177927	[345]	[134,128,NaN]	-1	hSpCas9	negative selection	9813374
15053806	15053829	19	+	27869803	PATU8988S	viability after 35 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	0.22598589461324015	[560]	[376,150,NaN]	2	hSpCas9	negative selection	9813375
15053937	15053960	19	+	27869803	PATU8988S	viability after 35 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.5845812153250691	[517]	[248,376,NaN]	6	hSpCas9	negative selection	9813376
15055438	15055461	19	+	27869803	PATU8988S	viability after 35 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.4472226346669194	[952]	[287,274,NaN]	-4	hSpCas9	negative selection	9813377
15055461	15055484	19	+	27869803	PATU8988S	viability after 35 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.09030869101147898	[716]	[274,339,NaN]	1	hSpCas9	negative selection	9813378
15056061	15056084	19	-	27869803	PATU8988S	viability after 35 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.40025484878770357	[451]	[110,164,NaN]	-4	hSpCas9	negative selection	9813379
15052257	15052280	19	+	27869803	PATU8988S	viability after 31 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.10867228571930043	[345]	[101,160,NaN]	-1	hSpCas9	negative selection	9895823
15053806	15053829	19	+	27869803	PATU8988S	viability after 31 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	0.32480428347241863	[560]	[361,175,NaN]	4	hSpCas9	negative selection	9895824
15053937	15053960	19	+	27869803	PATU8988S	viability after 31 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.7201655389976978	[517]	[257,444,NaN]	8	hSpCas9	negative selection	9895825
15055438	15055461	19	+	27869803	PATU8988S	viability after 31 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	-0.6164209964140194	[952]	[202,304,NaN]	-6	hSpCas9	negative selection	9895826
15055461	15055484	19	+	27869803	PATU8988S	viability after 31 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.22253883068819658	[716]	[249,439,NaN]	2	hSpCas9	negative selection	9895827
15056061	15056084	19	-	27869803	PATU8988S	viability after 31 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	-0.5663839508892066	[451]	[82,170,NaN]	-6	hSpCas9	negative selection	9895828
15052257	15052280	19	+	27869803	HPAFII	viability after 35 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	-0.5250157332211318	[103]	[37,34,NaN]	-3	hSpCas9	negative selection	9978272
15053806	15053829	19	+	27869803	HPAFII	viability after 35 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-1.1472945086791582	[227]	[37,67,NaN]	-6	hSpCas9	negative selection	9978273
15053937	15053960	19	+	27869803	HPAFII	viability after 35 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	1.0510698695611504	[196]	[208,203,NaN]	7	hSpCas9	negative selection	9978274
15055438	15055461	19	+	27869803	HPAFII	viability after 35 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.6730084019332698	[455]	[495,223,NaN]	4	hSpCas9	negative selection	9978275
15055461	15055484	19	+	27869803	HPAFII	viability after 35 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.40833551396803347	[394]	[215,320,NaN]	2	hSpCas9	negative selection	9978276
15056061	15056084	19	-	27869803	HPAFII	viability after 35 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.3165294399935282	[206]	[74,192,NaN]	2	hSpCas9	negative selection	9978277
15052257	15052280	19	+	27869803	HPAFII	viability after 31 days	CAATCCGCGGTCTTTGGAAGAGG	CASP14	ENSG00000105141	0.24578052227157254	[103]	[84,51,NaN]	1	hSpCas9	negative selection	10060721
15053806	15053829	19	+	27869803	HPAFII	viability after 31 days	TGGTACTCATGGCTCACGGGAGG	CASP14	ENSG00000105141	-0.9926117271150057	[227]	[59,68,NaN]	-6	hSpCas9	negative selection	10060722
15053937	15053960	19	+	27869803	HPAFII	viability after 31 days	ATCATACAGGCCTGTCGAGGAGG	CASP14	ENSG00000105141	0.9382186986954093	[196]	[174,251,NaN]	7	hSpCas9	negative selection	10060723
15055438	15055461	19	+	27869803	HPAFII	viability after 31 days	GCCTACCGACATGATCAGAAAGG	CASP14	ENSG00000105141	0.1342105604520798	[455]	[422,125,NaN]	1	hSpCas9	negative selection	10060724
15055461	15055484	19	+	27869803	HPAFII	viability after 31 days	CTCATGCTTTATCCAGACCCTGG	CASP14	ENSG00000105141	0.587721371566258	[394]	[291,377,NaN]	4	hSpCas9	negative selection	10060725
15056061	15056084	19	-	27869803	HPAFII	viability after 31 days	CAGATACAGCCGTTTCCGGAGGG	CASP14	ENSG00000105141	0.07112829227960882	[206]	[122,120,NaN]	0	hSpCas9	negative selection	10060726
15053807	15053830	19	+	28162770	P31FUJ	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.11325755294588163	[165]	[210]	1	hSpCas9	negative selection	10126175
15053822	15053845	19	+	28162770	P31FUJ	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.24665218317540294	[627]	[621]	-2	hSpCas9	negative selection	10126176
15053524	15053547	19	+	28162770	P31FUJ	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.1920830808208125	[291]	[391]	2	hSpCas9	negative selection	10126177
15053610	15053633	19	+	28162770	P31FUJ	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	-0.05965330209777997	[148]	[167]	0	hSpCas9	negative selection	10126178
15055263	15055286	19	-	28162770	P31FUJ	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3397174083308907	[125]	[116]	-3	hSpCas9	negative selection	10126179
15052244	15052267	19	+	28162770	P31FUJ	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.5041633897518274	[95]	[159]	6	hSpCas9	negative selection	10126180
15052261	15052284	19	-	28162770	P31FUJ	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.10087689616534096	[268]	[338]	1	hSpCas9	negative selection	10126181
15053541	15053564	19	+	28162770	P31FUJ	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.5607469181181952	[29]	[51]	6	hSpCas9	negative selection	10126182
15053621	15053644	19	-	28162770	P31FUJ	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.15383157986079898	[435]	[569]	1	hSpCas9	negative selection	10126183
15055166	15055189	19	+	28162770	P31FUJ	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.39980972247439667	[246]	[219]	-4	hSpCas9	negative selection	10126184
15053807	15053830	19	+	28162770	TF1	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10295541
15053822	15053845	19	+	28162770	TF1	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	NaN	[NaN]	[449]	1	hSpCas9	negative selection	10295542
15053524	15053547	19	+	28162770	TF1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	NaN	[NaN]	[264]	1	hSpCas9	negative selection	10295543
15053610	15053633	19	+	28162770	TF1	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10295544
15055263	15055286	19	-	28162770	TF1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10295545
15052244	15052267	19	+	28162770	TF1	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10295546
15052261	15052284	19	-	28162770	TF1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10295547
15053541	15053564	19	+	28162770	TF1	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10295548
15053621	15053644	19	-	28162770	TF1	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	NaN	[NaN]	[288]	1	hSpCas9	negative selection	10295549
15055166	15055189	19	+	28162770	TF1	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10295550
15053807	15053830	19	+	28162770	SKM1	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.029899662988860765	[40]	[73]	0	hSpCas9	negative selection	10464907
15053822	15053845	19	+	28162770	SKM1	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.02960646208532358	[132]	[239]	0	hSpCas9	negative selection	10464908
15053524	15053547	19	+	28162770	SKM1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-0.2190052744705876	[105]	[160]	-2	hSpCas9	negative selection	10464909
15053610	15053633	19	+	28162770	SKM1	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.34464817138744597	[48]	[109]	3	hSpCas9	negative selection	10464910
15055263	15055286	19	-	28162770	SKM1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.09763614063543297	[45]	[75]	-1	hSpCas9	negative selection	10464911
15052244	15052267	19	+	28162770	SKM1	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.5405683813627027	[20]	[53]	5	hSpCas9	negative selection	10464912
15052261	15052284	19	-	28162770	SKM1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.6042630566800925	[47]	[128]	6	hSpCas9	negative selection	10464913
15053541	15053564	19	+	28162770	SKM1	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-2.0443941193584534	[13]	[5]	-8	hSpCas9	negative selection	10464914
15053621	15053644	19	-	28162770	SKM1	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.2715724172901919	[96]	[206]	2	hSpCas9	negative selection	10464915
15055166	15055189	19	+	28162770	SKM1	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.37659054969964273	[46]	[63]	-3	hSpCas9	negative selection	10464916
15053807	15053830	19	+	28162770	SKM1	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.029899662988860765	[40]	[73]	0	hSpCas9	negative selection	10634273
15053822	15053845	19	+	28162770	SKM1	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.02960646208532358	[132]	[239]	0	hSpCas9	negative selection	10634274
15053524	15053547	19	+	28162770	SKM1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-0.2190052744705876	[105]	[160]	-2	hSpCas9	negative selection	10634275
15053610	15053633	19	+	28162770	SKM1	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.34464817138744597	[48]	[109]	3	hSpCas9	negative selection	10634276
15055263	15055286	19	-	28162770	SKM1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.09763614063543297	[45]	[75]	-1	hSpCas9	negative selection	10634277
15052244	15052267	19	+	28162770	SKM1	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.5405683813627027	[20]	[53]	5	hSpCas9	negative selection	10634278
15052261	15052284	19	-	28162770	SKM1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.6042630566800925	[47]	[128]	6	hSpCas9	negative selection	10634279
15053541	15053564	19	+	28162770	SKM1	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-2.0443941193584534	[13]	[5]	-8	hSpCas9	negative selection	10634280
15053621	15053644	19	-	28162770	SKM1	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.2715724172901919	[96]	[206]	2	hSpCas9	negative selection	10634281
15055166	15055189	19	+	28162770	SKM1	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.37659054969964273	[46]	[63]	-3	hSpCas9	negative selection	10634282
15053807	15053830	19	+	28162770	PL21	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.531590483495189	[150]	[94]	4	hSpCas9	negative selection	10803639
15053822	15053845	19	+	28162770	PL21	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.6917983953710767	[494]	[347]	6	hSpCas9	negative selection	10803640
15053524	15053547	19	+	28162770	PL21	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.5565311189449041	[363]	[232]	5	hSpCas9	negative selection	10803641
15053610	15053633	19	+	28162770	PL21	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	-0.17693003459050313	[199]	[76]	-1	hSpCas9	negative selection	10803642
15055263	15055286	19	-	28162770	PL21	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.14951354141935214	[173]	[83]	1	hSpCas9	negative selection	10803643
15052244	15052267	19	+	28162770	PL21	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.9230300234438034	[102]	[84]	7	hSpCas9	negative selection	10803644
15052261	15052284	19	-	28162770	PL21	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.0488879333505946	[163]	[68]	0	hSpCas9	negative selection	10803645
15053541	15053564	19	+	28162770	PL21	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	1.912857662408849	[35]	[58]	9	hSpCas9	negative selection	10803646
15053621	15053644	19	-	28162770	PL21	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.6249250903197262	[294]	[197]	5	hSpCas9	negative selection	10803647
15055166	15055189	19	+	28162770	PL21	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.57865123774305	[119]	[77]	5	hSpCas9	negative selection	10803648
15053807	15053830	19	+	28162770	P31FUJ	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.11325755294588163	[165]	[210]	1	hSpCas9	negative selection	10973005
15053822	15053845	19	+	28162770	P31FUJ	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.24665218317540294	[627]	[621]	-2	hSpCas9	negative selection	10973006
15053524	15053547	19	+	28162770	P31FUJ	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.1920830808208125	[291]	[391]	2	hSpCas9	negative selection	10973007
15053610	15053633	19	+	28162770	P31FUJ	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	-0.05965330209777997	[148]	[167]	0	hSpCas9	negative selection	10973008
15055263	15055286	19	-	28162770	P31FUJ	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3397174083308907	[125]	[116]	-3	hSpCas9	negative selection	10973009
15052244	15052267	19	+	28162770	P31FUJ	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.5041633897518274	[95]	[159]	6	hSpCas9	negative selection	10973010
15052261	15052284	19	-	28162770	P31FUJ	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.10087689616534096	[268]	[338]	1	hSpCas9	negative selection	10973011
15053541	15053564	19	+	28162770	P31FUJ	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.5607469181181952	[29]	[51]	6	hSpCas9	negative selection	10973012
15053621	15053644	19	-	28162770	P31FUJ	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.15383157986079898	[435]	[569]	1	hSpCas9	negative selection	10973013
15055166	15055189	19	+	28162770	P31FUJ	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.39980972247439667	[246]	[219]	-4	hSpCas9	negative selection	10973014
15053807	15053830	19	+	28162770	OCIAML5	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.6488316650686845	[52]	[149]	5	hSpCas9	negative selection	11142371
15053822	15053845	19	+	28162770	OCIAML5	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.6079136307887382	[281]	[333]	-4	hSpCas9	negative selection	11142372
15053524	15053547	19	+	28162770	OCIAML5	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-0.19697798375219877	[173]	[273]	-1	hSpCas9	negative selection	11142373
15053610	15053633	19	+	28162770	OCIAML5	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.4928924926787064	[86]	[220]	4	hSpCas9	negative selection	11142374
15055263	15055286	19	-	28162770	OCIAML5	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.3732257409782459	[70]	[165]	3	hSpCas9	negative selection	11142375
15052244	15052267	19	+	28162770	OCIAML5	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.992655203658092	[48]	[175]	8	hSpCas9	negative selection	11142376
15052261	15052284	19	-	28162770	OCIAML5	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.567923138436105	[146]	[178]	-4	hSpCas9	negative selection	11142377
15053541	15053564	19	+	28162770	OCIAML5	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	1.1479334291360028	[7]	[31]	8	hSpCas9	negative selection	11142378
15053621	15053644	19	-	28162770	OCIAML5	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.6983091183251092	[196]	[576]	6	hSpCas9	negative selection	11142379
15055166	15055189	19	+	28162770	OCIAML5	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.36825079359974056	[127]	[178]	-3	hSpCas9	negative selection	11142380
15053807	15053830	19	+	28162770	EOL1	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.2553613184443999	[289]	[127]	-2	hSpCas9	negative selection	11311737
15053822	15053845	19	+	28162770	EOL1	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.01994898747000562	[628]	[335]	0	hSpCas9	negative selection	11311738
15053524	15053547	19	+	28162770	EOL1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.7222145349128941	[618]	[537]	6	hSpCas9	negative selection	11311739
15053610	15053633	19	+	28162770	EOL1	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	-0.3893430042514094	[357]	[143]	-3	hSpCas9	negative selection	11311740
15055263	15055286	19	-	28162770	EOL1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.509025679145737	[234]	[86]	-4	hSpCas9	negative selection	11311741
15052244	15052267	19	+	28162770	EOL1	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.4758794944104106	[216]	[158]	4	hSpCas9	negative selection	11311742
15052261	15052284	19	-	28162770	EOL1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.20041049886028678	[228]	[104]	-1	hSpCas9	negative selection	11311743
15053541	15053564	19	+	28162770	EOL1	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	2.0218449729254493	[42]	[91]	9	hSpCas9	negative selection	11311744
15053621	15053644	19	-	28162770	EOL1	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.44715419494604064	[393]	[282]	4	hSpCas9	negative selection	11311745
15055166	15055189	19	+	28162770	EOL1	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.024083445121449	[223]	[119]	0	hSpCas9	negative selection	11311746
15053807	15053830	19	+	28162770	MOLM13	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.6378143829868913	[175]	[197]	5	hSpCas9	negative selection	11481103
15053822	15053845	19	+	28162770	MOLM13	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.9080978402936046	[570]	[219]	-5	hSpCas9	negative selection	11481104
15053524	15053547	19	+	28162770	MOLM13	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.20485497571078504	[467]	[389]	1	hSpCas9	negative selection	11481105
15053610	15053633	19	+	28162770	MOLM13	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.2986525246614087	[261]	[232]	2	hSpCas9	negative selection	11481106
15055263	15055286	19	-	28162770	MOLM13	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.6773735656634645	[260]	[117]	-4	hSpCas9	negative selection	11481107
15052244	15052267	19	+	28162770	MOLM13	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.3752400935789043	[208]	[195]	2	hSpCas9	negative selection	11481108
15052261	15052284	19	-	28162770	MOLM13	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.3054486022865893	[240]	[140]	-2	hSpCas9	negative selection	11481109
15053541	15053564	19	+	28162770	MOLM13	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-0.6364472782701571	[42]	[19]	-4	hSpCas9	negative selection	11481110
15053621	15053644	19	-	28162770	MOLM13	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.022935188512570703	[481]	[342]	0	hSpCas9	negative selection	11481111
15055166	15055189	19	+	28162770	MOLM13	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.6224968549125267	[246]	[115]	-4	hSpCas9	negative selection	11481112
15053807	15053830	19	+	28162770	HEL	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	0.490735738555307	[159]	[143]	4	hSpCas9	negative selection	11650469
15053822	15053845	19	+	28162770	HEL	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	-0.24940517823897523	[437]	[235]	-2	hSpCas9	negative selection	11650470
15053524	15053547	19	+	28162770	HEL	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	-1.4325492953038803	[471]	[111]	-7	hSpCas9	negative selection	11650471
15053610	15053633	19	+	28162770	HEL	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	-0.9277965980855196	[198]	[66]	-5	hSpCas9	negative selection	11650472
15055263	15055286	19	-	28162770	HEL	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	0.07714165614613187	[258]	[174]	0	hSpCas9	negative selection	11650473
15052244	15052267	19	+	28162770	HEL	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	-0.04410328274001263	[131]	[81]	0	hSpCas9	negative selection	11650474
15052261	15052284	19	-	28162770	HEL	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-1.4068919357242438	[206]	[49]	-7	hSpCas9	negative selection	11650475
15053541	15053564	19	+	28162770	HEL	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	0.01047061650084391	[30]	[19]	0	hSpCas9	negative selection	11650476
15053621	15053644	19	-	28162770	HEL	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-1.0117646019738762	[424]	[134]	-6	hSpCas9	negative selection	11650477
15055166	15055189	19	+	28162770	HEL	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-1.566714533628593	[184]	[39]	-7	hSpCas9	negative selection	11650478
15053807	15053830	19	+	28162770	MV411	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-1.7849839269096022	[134]	[32]	-8	hSpCas9	negative selection	11819835
15053822	15053845	19	+	28162770	MV411	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.1884020804858233	[423]	[406]	1	hSpCas9	negative selection	11819836
15053524	15053547	19	+	28162770	MV411	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.15185989080054418	[311]	[291]	1	hSpCas9	negative selection	11819837
15053610	15053633	19	+	28162770	MV411	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.8424537161678545	[142]	[215]	7	hSpCas9	negative selection	11819838
15055263	15055286	19	-	28162770	MV411	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-1.725927322713758	[160]	[40]	-8	hSpCas9	negative selection	11819839
15052244	15052267	19	+	28162770	MV411	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	-0.970985968350727	[120]	[51]	-6	hSpCas9	negative selection	11819840
15052261	15052284	19	-	28162770	MV411	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.8667334691365359	[183]	[84]	-5	hSpCas9	negative selection	11819841
15053541	15053564	19	+	28162770	MV411	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	1.639754973561536	[15]	[41]	9	hSpCas9	negative selection	11819842
15053621	15053644	19	-	28162770	MV411	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.12692474346554095	[286]	[263]	1	hSpCas9	negative selection	11819843
15055166	15055189	19	+	28162770	MV411	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.729306558539828	[115]	[161]	6	hSpCas9	negative selection	11819844
15053807	15053830	19	+	28162770	MONOMAC1	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.4470151000679012	[87]	[73]	-4	hSpCas9	negative selection	11989201
15053822	15053845	19	+	28162770	MONOMAC1	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.044302487674921176	[334]	[395]	0	hSpCas9	negative selection	11989202
15053524	15053547	19	+	28162770	MONOMAC1	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.587234461885009	[215]	[371]	6	hSpCas9	negative selection	11989203
15053610	15053633	19	+	28162770	MONOMAC1	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.21192613780960573	[118]	[157]	2	hSpCas9	negative selection	11989204
15055263	15055286	19	-	28162770	MONOMAC1	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.002864299370563976	[117]	[134]	0	hSpCas9	negative selection	11989205
15052244	15052267	19	+	28162770	MONOMAC1	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	-0.8018989052184148	[72]	[47]	-6	hSpCas9	negative selection	11989206
15052261	15052284	19	-	28162770	MONOMAC1	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.3879256536616024	[117]	[176]	4	hSpCas9	negative selection	11989207
15053541	15053564	19	+	28162770	MONOMAC1	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-2.004391769117158	[20]	[5]	-8	hSpCas9	negative selection	11989208
15053621	15053644	19	-	28162770	MONOMAC1	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	-0.07999742586933434	[212]	[230]	0	hSpCas9	negative selection	11989209
15055166	15055189	19	+	28162770	MONOMAC1	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	-0.6824636742297954	[97]	[69]	-5	hSpCas9	negative selection	11989210
15053807	15053830	19	+	28162770	OCIAML2	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	-0.8221021957435389	[36]	[115]	-5	hSpCas9	negative selection	12158567
15053822	15053845	19	+	28162770	OCIAML2	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.5145122160307256	[60]	[482]	5	hSpCas9	negative selection	12158568
15053524	15053547	19	+	28162770	OCIAML2	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.49284429873272484	[49]	[389]	5	hSpCas9	negative selection	12158569
15053610	15053633	19	+	28162770	OCIAML2	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.009996015664259339	[42]	[239]	0	hSpCas9	negative selection	12158570
15055263	15055286	19	-	28162770	OCIAML2	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.4979371712378965	[39]	[156]	-4	hSpCas9	negative selection	12158571
15052244	15052267	19	+	28162770	OCIAML2	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	0.23902842292830961	[23]	[156]	2	hSpCas9	negative selection	12158572
15052261	15052284	19	-	28162770	OCIAML2	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	-0.156314914464674	[37]	[188]	-1	hSpCas9	negative selection	12158573
15053541	15053564	19	+	28162770	OCIAML2	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-0.8856673245210049	[9]	[29]	-6	hSpCas9	negative selection	12158574
15053621	15053644	19	-	28162770	OCIAML2	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.3669397098624506	[53]	[385]	3	hSpCas9	negative selection	12158575
15055166	15055189	19	+	28162770	OCIAML2	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	0.8562645225385505	[28]	[290]	8	hSpCas9	negative selection	12158576
15053807	15053830	19	+	28162770	OCIAML3	viability	GGTACTCATGGCTCACGGGAGGG	CASP14	ENSG00000105141	1.172895237996147	[30]	[210]	8	hSpCas9	negative selection	12327933
15053822	15053845	19	+	28162770	OCIAML3	viability	CGGGAGGGAAGGCTTCCTCAAGG	CASP14	ENSG00000105141	0.73672635193854	[97]	[492]	6	hSpCas9	negative selection	12327934
15053524	15053547	19	+	28162770	OCIAML3	viability	TGTGTCACCAAAGCCCGGGAAGG	CASP14	ENSG00000105141	0.07810680949207494	[90]	[289]	0	hSpCas9	negative selection	12327935
15053610	15053633	19	+	28162770	OCIAML3	viability	GAAAAGAGACCCCACTGCCGAGG	CASP14	ENSG00000105141	0.24356189478044876	[53]	[192]	2	hSpCas9	negative selection	12327936
15055263	15055286	19	-	28162770	OCIAML3	viability	GGAGCTCATACCCTCTACCGTGG	CASP14	ENSG00000105141	-0.3071264925360017	[49]	[121]	-2	hSpCas9	negative selection	12327937
15052244	15052267	19	+	28162770	OCIAML3	viability	AAGGAGAAATGAGCAATCCGCGG	CASP14	ENSG00000105141	-0.31107367705266453	[29]	[72]	-2	hSpCas9	negative selection	12327938
15052261	15052284	19	-	28162770	OCIAML3	viability	CCTACCTCTTCCAAAGACCGCGG	CASP14	ENSG00000105141	0.4625758880422043	[49]	[207]	4	hSpCas9	negative selection	12327939
15053541	15053564	19	+	28162770	OCIAML3	viability	GGAAGGTTCCGAAGAAGACCTGG	CASP14	ENSG00000105141	-0.40136256238176715	[13]	[31]	-3	hSpCas9	negative selection	12327940
15053621	15053644	19	-	28162770	OCIAML3	viability	GCACCCCAATACCTCGGCAGTGG	CASP14	ENSG00000105141	0.042401625815669086	[100]	[313]	0	hSpCas9	negative selection	12327941
15055166	15055189	19	+	28162770	OCIAML3	viability	GACCCCGGTGAAACAGTAGGTGG	CASP14	ENSG00000105141	1.4107302786825	[37]	[304]	9	hSpCas9	negative selection	12327942