Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 835
• Symbol: CASP2
• Description: caspase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
143288453	143288476	7	+	26472758	Jiyoye	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	-0.914752713381489	[74]	[29]	-6	hSpCas9	negative selection	23739
143292288	143292311	7	+	26472758	Jiyoye	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	-0.0012894638494842514	[145]	[109]	0	hSpCas9	negative selection	23740
143288501	143288524	7	+	26472758	Jiyoye	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.8685065330586521	[137]	[189]	6	hSpCas9	negative selection	23741
143292361	143292384	7	-	26472758	Jiyoye	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	1.1979985796735892	[162]	[281]	7	hSpCas9	negative selection	23742
143291648	143291671	7	+	26472758	Jiyoye	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.23082242664507446	[477]	[422]	1	hSpCas9	negative selection	23743
143292308	143292331	7	+	26472758	Jiyoye	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.8550665619077955	[444]	[606]	6	hSpCas9	negative selection	23744
143291669	143291692	7	+	26472758	Jiyoye	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.6797012363169648	[100]	[121]	5	hSpCas9	negative selection	23745
143291633	143291656	7	+	26472758	Jiyoye	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	-0.22830889479444894	[246]	[158]	-2	hSpCas9	negative selection	23746
143288465	143288488	7	-	26472758	Jiyoye	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	-0.42592730974938225	[211]	[118]	-3	hSpCas9	negative selection	23747
143288511	143288534	7	-	26472758	Jiyoye	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.1176687643108885	[21]	[35]	7	hSpCas9	negative selection	23748
143288453	143288476	7	+	26472758	KBM7	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.1286421064469072	[213,137]	[99,78]	1	hSpCas9	negative selection	214857
143292288	143292311	7	+	26472758	KBM7	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.3540139582000148	[597,472]	[384,260]	4	hSpCas9	negative selection	214858
143288501	143288524	7	+	26472758	KBM7	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.6091167577692973	[621,593]	[424,447]	6	hSpCas9	negative selection	214859
143292361	143292384	7	-	26472758	KBM7	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.587469636653431	[646,531]	[350,470]	6	hSpCas9	negative selection	214860
143291648	143291671	7	+	26472758	KBM7	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.46743356335906583	[1459,1123]	[797,863]	5	hSpCas9	negative selection	214861
143292308	143292331	7	+	26472758	KBM7	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.2674034639155405	[2195,1599]	[1276,869]	2	hSpCas9	negative selection	214862
143291669	143291692	7	+	26472758	KBM7	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.5418059566244714	[425,466]	[250,359]	6	hSpCas9	negative selection	214863
143291633	143291656	7	+	26472758	KBM7	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.31856723855435565	[775,788]	[518,409]	3	hSpCas9	negative selection	214864
143288465	143288488	7	-	26472758	KBM7	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.8234519847115828	[505,521]	[525,344]	8	hSpCas9	negative selection	214865
143288511	143288534	7	-	26472758	KBM7	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.6135436348907963	[114,197]	[140,93]	6	hSpCas9	negative selection	214866
143288453	143288476	7	+	26472758	Raji	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.42700146957376084	[124]	[38]	4	hSpCas9	negative selection	405975
143292288	143292311	7	+	26472758	Raji	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.5476215887775858	[226]	[76]	5	hSpCas9	negative selection	405976
143288501	143288524	7	+	26472758	Raji	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.3650347445104901	[357]	[106]	3	hSpCas9	negative selection	405977
143292361	143292384	7	-	26472758	Raji	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5831750657315395	[278]	[96]	5	hSpCas9	negative selection	405978
143291648	143291671	7	+	26472758	Raji	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.6453207012688682	[685]	[248]	6	hSpCas9	negative selection	405979
143292308	143292331	7	+	26472758	Raji	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.8346740685020244	[777]	[321]	7	hSpCas9	negative selection	405980
143291669	143291692	7	+	26472758	Raji	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.8510437821138139	[214]	[89]	7	hSpCas9	negative selection	405981
143291633	143291656	7	+	26472758	Raji	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	-0.13162359981374494	[523]	[110]	-1	hSpCas9	negative selection	405982
143288465	143288488	7	-	26472758	Raji	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.14238998520151286	[284]	[72]	1	hSpCas9	negative selection	405983
143288511	143288534	7	-	26472758	Raji	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	2.1073835353735992	[24]	[24]	9	hSpCas9	negative selection	405984
143288453	143288476	7	+	26472758	K562	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.8412945499311038	[200]	[303]	7	hSpCas9	negative selection	597093
143292288	143292311	7	+	26472758	K562	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	1.5603230349260393	[383]	[955]	9	hSpCas9	negative selection	597094
143288501	143288524	7	+	26472758	K562	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.46050711231892283	[556]	[646]	3	hSpCas9	negative selection	597095
143292361	143292384	7	-	26472758	K562	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.7387971556812172	[481]	[678]	6	hSpCas9	negative selection	597096
143291648	143291671	7	+	26472758	K562	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.39282231976600146	[922]	[1022]	3	hSpCas9	negative selection	597097
143292308	143292331	7	+	26472758	K562	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.7199735790254453	[1633]	[2271]	6	hSpCas9	negative selection	597098
143291669	143291692	7	+	26472758	K562	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.0264872081131924	[295]	[508]	8	hSpCas9	negative selection	597099
143291633	143291656	7	+	26472758	K562	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.94675964754223	[699]	[1138]	7	hSpCas9	negative selection	597100
143288465	143288488	7	-	26472758	K562	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	1.1159039871437666	[263]	[482]	8	hSpCas9	negative selection	597101
143288511	143288534	7	-	26472758	K562	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.4024205617329402	[107]	[240]	9	hSpCas9	negative selection	597102
143292287	143292310	7	+	26627737	DLD1	viability	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.7509437480447434	[548]	[260,400,219]	7	hSpCas9	negative selection	835332
143292685	143292708	7	-	26627737	DLD1	viability	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.346368626093815	[160]	[78,40,69]	3	hSpCas9	negative selection	835333
143294614	143294637	7	+	26627737	DLD1	viability	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	-0.0344389909488122	[281]	[100,49,102]	0	hSpCas9	negative selection	835334
143299986	143300009	7	+	26627737	DLD1	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6360075545803585	[936]	[183,708,479]	6	hSpCas9	negative selection	835335
143300191	143300214	7	+	26627737	DLD1	viability	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.26998577887565145	[466]	[190,227,119]	2	hSpCas9	negative selection	835336
143303892	143303915	7	-	26627737	DLD1	viability	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	-0.3524318919835132	[1371]	[428,363,231]	-4	hSpCas9	negative selection	835337
143292287	143292310	7	+	26627737	GBM cells	viability after 5 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.4527886978227447	[343]	[247,256]	6	hSpCas9	negative selection	917647
143292685	143292708	7	-	26627737	GBM cells	viability after 5 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.15045264188164986	[104]	[69,54]	2	hSpCas9	negative selection	917648
143294614	143294637	7	+	26627737	GBM cells	viability after 5 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	-0.20201503396509513	[147]	[56,80]	-3	hSpCas9	negative selection	917649
143299986	143300009	7	+	26627737	GBM cells	viability after 5 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.17798649081125084	[327]	[187,209]	3	hSpCas9	negative selection	917650
143300191	143300214	7	+	26627737	GBM cells	viability after 5 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.09051314267653043	[344]	[235,157]	1	hSpCas9	negative selection	917651
143303892	143303915	7	-	26627737	GBM cells	viability after 5 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.16298656434895642	[462]	[283,271]	2	hSpCas9	negative selection	917652
143292287	143292310	7	+	26627737	GBM cells	viability after 13 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.7101028177513051	[343]	[290,316]	8	hSpCas9	negative selection	999962
143292685	143292708	7	-	26627737	GBM cells	viability after 13 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.547108543310679	[104]	[85,80]	6	hSpCas9	negative selection	999963
143294614	143294637	7	+	26627737	GBM cells	viability after 13 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	-0.12263526698109195	[147]	[70,75]	-1	hSpCas9	negative selection	999964
143299986	143300009	7	+	26627737	GBM cells	viability after 13 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.37551926994280205	[327]	[258,207]	5	hSpCas9	negative selection	999965
143300191	143300214	7	+	26627737	GBM cells	viability after 13 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.3068854935493338	[344]	[246,218]	4	hSpCas9	negative selection	999966
143303892	143303915	7	-	26627737	GBM cells	viability after 13 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.48913543879246946	[462]	[313,383]	6	hSpCas9	negative selection	999967
143292287	143292310	7	+	26627737	GBM cells	viability after 21 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	1.1489647799441347	[343]	[415,412]	9	hSpCas9	negative selection	1082277
143292685	143292708	7	-	26627737	GBM cells	viability after 21 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.677652597728463	[104]	[108,74]	6	hSpCas9	negative selection	1082278
143294614	143294637	7	+	26627737	GBM cells	viability after 21 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	-0.6131437168312995	[147]	[50,53]	-5	hSpCas9	negative selection	1082279
143299986	143300009	7	+	26627737	GBM cells	viability after 21 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6304505204970334	[327]	[290,261]	6	hSpCas9	negative selection	1082280
143300191	143300214	7	+	26627737	GBM cells	viability after 21 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.6463418940576975	[344]	[319,268]	6	hSpCas9	negative selection	1082281
143303892	143303915	7	-	26627737	GBM cells	viability after 21 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	1.180576689638484	[462]	[589,551]	9	hSpCas9	negative selection	1082282
143292287	143292310	7	+	26627737	RPE1	viability after 9 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.5242062376683451	[2010]	[387,501]	-4	hSpCas9	negative selection	1164592
143292685	143292708	7	-	26627737	RPE1	viability after 9 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.17444373110606604	[246]	[47,94]	-1	hSpCas9	negative selection	1164593
143294614	143294637	7	+	26627737	RPE1	viability after 9 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.4613110147121927	[682]	[334,241]	3	hSpCas9	negative selection	1164594
143299986	143300009	7	+	26627737	RPE1	viability after 9 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6156690312529728	[963]	[306,662]	4	hSpCas9	negative selection	1164595
143300191	143300214	7	+	26627737	RPE1	viability after 9 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.9801740713457427	[814]	[453,566]	6	hSpCas9	negative selection	1164596
143303892	143303915	7	-	26627737	RPE1	viability after 9 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.981697535057912	[1175]	[692,770]	6	hSpCas9	negative selection	1164597
143292287	143292310	7	+	26627737	RPE1	viability after 12 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.2363136572546618	[2010]	[429,488]	-2	hSpCas9	negative selection	1246907
143292685	143292708	7	-	26627737	RPE1	viability after 12 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.48196638356923716	[246]	[47,46]	-3	hSpCas9	negative selection	1246908
143294614	143294637	7	+	26627737	RPE1	viability after 12 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.039336935571258946	[682]	[173,203]	0	hSpCas9	negative selection	1246909
143299986	143300009	7	+	26627737	RPE1	viability after 12 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.27967948281442034	[963]	[225,407]	2	hSpCas9	negative selection	1246910
143300191	143300214	7	+	26627737	RPE1	viability after 12 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	1.1339764556078331	[814]	[447,514]	6	hSpCas9	negative selection	1246911
143303892	143303915	7	-	26627737	RPE1	viability after 12 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	1.1582692787832736	[1175]	[744,662]	7	hSpCas9	negative selection	1246912
143292287	143292310	7	+	26627737	RPE1	viability after 15 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.5267851323564005	[2010]	[346,440]	-3	hSpCas9	negative selection	1329222
143292685	143292708	7	-	26627737	RPE1	viability after 15 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.4517671420251592	[246]	[91,98]	3	hSpCas9	negative selection	1329223
143294614	143294637	7	+	26627737	RPE1	viability after 15 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.8814746231054167	[682]	[443,270]	5	hSpCas9	negative selection	1329224
143299986	143300009	7	+	26627737	RPE1	viability after 15 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.7265594743408771	[963]	[297,598]	4	hSpCas9	negative selection	1329225
143300191	143300214	7	+	26627737	RPE1	viability after 15 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	1.3435807090130094	[814]	[439,724]	7	hSpCas9	negative selection	1329226
143303892	143303915	7	-	26627737	RPE1	viability after 15 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	1.3231202775053486	[1175]	[868,796]	7	hSpCas9	negative selection	1329227
143292287	143292310	7	+	26627737	RPE1	viability after 18 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.22484028014883473	[2010]	[431,498]	-1	hSpCas9	negative selection	1411537
143292685	143292708	7	-	26627737	RPE1	viability after 18 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.4087134182885692	[246]	[58,119]	2	hSpCas9	negative selection	1411538
143294614	143294637	7	+	26627737	RPE1	viability after 18 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.7853466164975855	[682]	[351,280]	5	hSpCas9	negative selection	1411539
143299986	143300009	7	+	26627737	RPE1	viability after 18 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.49118916466741047	[963]	[224,515]	3	hSpCas9	negative selection	1411540
143300191	143300214	7	+	26627737	RPE1	viability after 18 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.8844658098557323	[814]	[304,513]	5	hSpCas9	negative selection	1411541
143303892	143303915	7	-	26627737	RPE1	viability after 18 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	1.2225872759534324	[1175]	[714,767]	7	hSpCas9	negative selection	1411542
143292287	143292310	7	+	26627737	HeLa	viability after 8 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.1508210811056222	[525]	[351,253,182]	1	hSpCas9	negative selection	1493852
143292685	143292708	7	-	26627737	HeLa	viability after 8 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.7775585561276515	[112]	[96,108,51]	6	hSpCas9	negative selection	1493853
143294614	143294637	7	+	26627737	HeLa	viability after 8 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	1.273546552444221	[119]	[174,140,76]	8	hSpCas9	negative selection	1493854
143299986	143300009	7	+	26627737	HeLa	viability after 8 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.29192575747826655	[620]	[328,360,303]	2	hSpCas9	negative selection	1493855
143300191	143300214	7	+	26627737	HeLa	viability after 8 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.37503975691964675	[419]	[267,214,234]	3	hSpCas9	negative selection	1493856
143303892	143303915	7	-	26627737	HeLa	viability after 8 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.803750105798153	[590]	[573,376,424]	6	hSpCas9	negative selection	1493857
143292287	143292310	7	+	26627737	HeLa	viability after 12 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.10243544554459555	[525]	[177,180,249]	-1	hSpCas9	negative selection	1576167
143292685	143292708	7	-	26627737	HeLa	viability after 12 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.5888771817466047	[112]	[16,37,36]	-5	hSpCas9	negative selection	1576168
143294614	143294637	7	+	26627737	HeLa	viability after 12 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	1.9380736792600253	[119]	[278,120,179]	9	hSpCas9	negative selection	1576169
143299986	143300009	7	+	26627737	HeLa	viability after 12 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4332681469817121	[620]	[461,298,286]	3	hSpCas9	negative selection	1576170
143300191	143300214	7	+	26627737	HeLa	viability after 12 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.654119396708039	[419]	[131,379,291]	5	hSpCas9	negative selection	1576171
143303892	143303915	7	-	26627737	HeLa	viability after 12 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.0018193366667530464	[590]	[218,337,165]	0	hSpCas9	negative selection	1576172
143292287	143292310	7	+	26627737	HeLa	viability after 15 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.11566784980731659	[525]	[318,166,206]	1	hSpCas9	negative selection	1658482
143292685	143292708	7	-	26627737	HeLa	viability after 15 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.5314143644697016	[112]	[21,99,78]	4	hSpCas9	negative selection	1658483
143294614	143294637	7	+	26627737	HeLa	viability after 15 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.8418808957562676	[119]	[100,55,106]	6	hSpCas9	negative selection	1658484
143299986	143300009	7	+	26627737	HeLa	viability after 15 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.9168960453803241	[620]	[314,424,711]	7	hSpCas9	negative selection	1658485
143300191	143300214	7	+	26627737	HeLa	viability after 15 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.5201734807525804	[419]	[238,235,261]	4	hSpCas9	negative selection	1658486
143303892	143303915	7	-	26627737	HeLa	viability after 15 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.698059121100132	[590]	[458,490,205]	5	hSpCas9	negative selection	1658487
143292287	143292310	7	+	26627737	HeLa	viability after 18 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.09939142634572373	[525]	[209,136,206]	0	hSpCas9	negative selection	1740797
143292685	143292708	7	-	26627737	HeLa	viability after 18 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.5491160462511648	[112]	[12,86,78]	4	hSpCas9	negative selection	1740798
143294614	143294637	7	+	26627737	HeLa	viability after 18 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.8413447614691486	[119]	[63,50,106]	6	hSpCas9	negative selection	1740799
143299986	143300009	7	+	26627737	HeLa	viability after 18 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.9161445575486087	[620]	[217,342,711]	7	hSpCas9	negative selection	1740800
143300191	143300214	7	+	26627737	HeLa	viability after 18 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.5247259899036194	[419]	[162,193,261]	4	hSpCas9	negative selection	1740801
143303892	143303915	7	-	26627737	HeLa	viability after 18 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.6987760639882697	[590]	[307,406,205]	5	hSpCas9	negative selection	1740802
143292287	143292310	7	+	26627737	HCT116	viability after 6 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-2.8198143205704653	[916]	[51,2]	-9	hSpCas9	negative selection	1823112
143292685	143292708	7	-	26627737	HCT116	viability after 6 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-2.0637785448311434	[90]	[5,1]	-8	hSpCas9	negative selection	1823113
143294614	143294637	7	+	26627737	HCT116	viability after 6 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.09115038219028454	[433]	[140,34]	0	hSpCas9	negative selection	1823114
143299986	143300009	7	+	26627737	HCT116	viability after 6 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.28163063007239364	[1123]	[223,101]	-1	hSpCas9	negative selection	1823115
143300191	143300214	7	+	26627737	HCT116	viability after 6 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.4981307490557762	[618]	[23,199]	2	hSpCas9	negative selection	1823116
143303892	143303915	7	-	26627737	HCT116	viability after 6 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.6719140776731758	[1111]	[545,130]	4	hSpCas9	negative selection	1823117
143292287	143292310	7	+	26627737	HCT116	viability after 8 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.13798944245959793	[459]	[258,237,194]	-1	hSpCas9	negative selection	1905427
143292685	143292708	7	-	26627737	HCT116	viability after 8 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.4253630931143568	[151]	[51,78,55]	-5	hSpCas9	negative selection	1905428
143294614	143294637	7	+	26627737	HCT116	viability after 8 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.33141913109765564	[167]	[103,110,133]	3	hSpCas9	negative selection	1905429
143299986	143300009	7	+	26627737	HCT116	viability after 8 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.004844845574280554	[418]	[237,266,185]	0	hSpCas9	negative selection	1905430
143300191	143300214	7	+	26627737	HCT116	viability after 8 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.9348468194052657	[199]	[197,238,194]	8	hSpCas9	negative selection	1905431
143303892	143303915	7	-	26627737	HCT116	viability after 8 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.591405021905922	[487]	[408,356,448]	6	hSpCas9	negative selection	1905432
143292287	143292310	7	+	26627737	HCT116	viability after 9 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.31195604228605406	[916]	[399,36]	-2	hSpCas9	negative selection	1987742
143292685	143292708	7	-	26627737	HCT116	viability after 9 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	1.811623295539281	[90]	[153,30]	9	hSpCas9	negative selection	1987743
143294614	143294637	7	+	26627737	HCT116	viability after 9 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	-0.7731180313107879	[433]	[102,39]	-5	hSpCas9	negative selection	1987744
143299986	143300009	7	+	26627737	HCT116	viability after 9 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.2983796021281868	[1123]	[233,251]	-2	hSpCas9	negative selection	1987745
143300191	143300214	7	+	26627737	HCT116	viability after 9 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	-0.08073992634779922	[618]	[143,165]	0	hSpCas9	negative selection	1987746
143303892	143303915	7	-	26627737	HCT116	viability after 9 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.03692327436393872	[1111]	[622,52]	0	hSpCas9	negative selection	1987747
143292287	143292310	7	+	26627737	HCT116	viability after 12 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.24202622817102282	[459]	[190,187,234]	-3	hSpCas9	negative selection	2070057
143292685	143292708	7	-	26627737	HCT116	viability after 12 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.509373112487896	[151]	[40,27,99]	-5	hSpCas9	negative selection	2070058
143294614	143294637	7	+	26627737	HCT116	viability after 12 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.7239112927525393	[167]	[149,182,104]	6	hSpCas9	negative selection	2070059
143299986	143300009	7	+	26627737	HCT116	viability after 12 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.17627788194392707	[418]	[237,273,235]	1	hSpCas9	negative selection	2070060
143300191	143300214	7	+	26627737	HCT116	viability after 12 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	1.3420852319549303	[199]	[171,320,315]	8	hSpCas9	negative selection	2070061
143303892	143303915	7	-	26627737	HCT116	viability after 12 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.8935721860289759	[487]	[421,554,458]	7	hSpCas9	negative selection	2070062
143292287	143292310	7	+	26627737	HCT116	viability after 15 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.0056955395210838144	[459]	[164,227,382]	0	hSpCas9	negative selection	2152372
143292685	143292708	7	-	26627737	HCT116	viability after 15 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.26542920160823025	[151]	[59,55,99]	-3	hSpCas9	negative selection	2152373
143294614	143294637	7	+	26627737	HCT116	viability after 15 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.4698129724786457	[167]	[84,180,128]	4	hSpCas9	negative selection	2152374
143299986	143300009	7	+	26627737	HCT116	viability after 15 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.2782474095634327	[418]	[219,378,267]	2	hSpCas9	negative selection	2152375
143300191	143300214	7	+	26627737	HCT116	viability after 15 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	1.1361788174624283	[199]	[180,258,307]	8	hSpCas9	negative selection	2152376
143303892	143303915	7	-	26627737	HCT116	viability after 15 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.6184148364416634	[487]	[482,370,442]	5	hSpCas9	negative selection	2152377
143292287	143292310	7	+	26627737	HCT116	viability after 18 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.19331736495850077	[459]	[192,147,247]	-2	hSpCas9	negative selection	2234687
143292685	143292708	7	-	26627737	HCT116	viability after 18 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.8710881354716655	[151]	[26,32,61]	-7	hSpCas9	negative selection	2234688
143294614	143294637	7	+	26627737	HCT116	viability after 18 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.6862978477670787	[167]	[77,212,93]	5	hSpCas9	negative selection	2234689
143299986	143300009	7	+	26627737	HCT116	viability after 18 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.644987421810618	[418]	[250,328,371]	5	hSpCas9	negative selection	2234690
143300191	143300214	7	+	26627737	HCT116	viability after 18 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.5024178116185628	[199]	[110,163,133]	4	hSpCas9	negative selection	2234691
143303892	143303915	7	-	26627737	HCT116	viability after 18 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.6720776259452629	[487]	[377,252,510]	5	hSpCas9	negative selection	2234692
143291555	143291578	7	+	24336569	HL60	viability	TGGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.40202318552653915	[637]	[1783]	3	hSpCas9	negative selection	2254466
143291565	143291588	7	-	24336569	HL60	viability	TTTAGAGTTTCCTGATGATGAGG	CASP2	ENSG00000106144	0.8490074738235599	[355]	[1356]	7	hSpCas9	negative selection	2254467
143291594	143291617	7	-	24336569	HL60	viability	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	2.412273640045721	[169]	[1914]	9	hSpCas9	negative selection	2254468
143291608	143291631	7	-	24336569	HL60	viability	TTCGCTCAACAACAGCTGTTTGG	CASP2	ENSG00000106144	0.03455568732804348	[817]	[1772]	0	hSpCas9	negative selection	2254469
143291627	143291650	7	+	24336569	HL60	viability	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.030540165466223845	[166]	[345]	0	hSpCas9	negative selection	2254470
143291633	143291656	7	+	24336569	HL60	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.2381902427383451	[126]	[316]	2	hSpCas9	negative selection	2254471
143291648	143291671	7	+	24336569	HL60	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	-0.2574944647203956	[887]	[1571]	-2	hSpCas9	negative selection	2254472
143291656	143291679	7	+	24336569	HL60	viability	ACATCATCACCTTGGAAATGAGG	CASP2	ENSG00000106144	-0.4617039286973337	[709]	[1090]	-4	hSpCas9	negative selection	2254473
143291665	143291688	7	-	24336569	HL60	viability	GATGAGCTCCCTCATTTCCAAGG	CASP2	ENSG00000106144	0.6600887630329615	[313]	[1049]	5	hSpCas9	negative selection	2254474
143292287	143292310	7	+	24336569	HL60	viability	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	2.482480618823177	[120]	[1430]	9	hSpCas9	negative selection	2254475
143291555	143291578	7	+	24336569	KBM7	viability	TGGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.17808899928549193	[628]	[1940]	1	hSpCas9	negative selection	2321643
143291565	143291588	7	-	24336569	KBM7	viability	TTTAGAGTTTCCTGATGATGAGG	CASP2	ENSG00000106144	-0.13839959440350838	[340]	[844]	-1	hSpCas9	negative selection	2321644
143291594	143291617	7	-	24336569	KBM7	viability	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.9219332601560202	[333]	[1725]	7	hSpCas9	negative selection	2321645
143291608	143291631	7	-	24336569	KBM7	viability	TTCGCTCAACAACAGCTGTTTGG	CASP2	ENSG00000106144	0.5855876673863168	[386]	[1583]	5	hSpCas9	negative selection	2321646
143291627	143291650	7	+	24336569	KBM7	viability	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	0.7675968859883302	[271]	[1262]	7	hSpCas9	negative selection	2321647
143291633	143291656	7	+	24336569	KBM7	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	-0.017228641775534514	[163]	[441]	0	hSpCas9	negative selection	2321648
143291648	143291671	7	+	24336569	KBM7	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.29339417938572865	[682]	[2282]	2	hSpCas9	negative selection	2321649
143291656	143291679	7	+	24336569	KBM7	viability	ACATCATCACCTTGGAAATGAGG	CASP2	ENSG00000106144	0.87651673502119	[398]	[1997]	7	hSpCas9	negative selection	2321650
143291665	143291688	7	-	24336569	KBM7	viability	GATGAGCTCCCTCATTTCCAAGG	CASP2	ENSG00000106144	0.7579069901163744	[373]	[1724]	6	hSpCas9	negative selection	2321651
143292287	143292310	7	+	24336569	KBM7	viability	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	1.7162261985135316	[104]	[940]	9	hSpCas9	negative selection	2321652
143288459	143288483	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCGGCGCCGAGCGCGGGGTCTTGG	CASP2	ENSG00000106144	1.0123866041266665	[1649,923,1200]	[0,0,0]	3	hSpCas9	positive selection	2380636
143291577	143291602	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GAAACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.5816652672580195	[1398,1919,1707]	[0,0,0]	2	hSpCas9	positive selection	2380637
143288501	143288524	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	1.2208687562028466	[1115,1165,961]	[0,0,0]	4	hSpCas9	positive selection	2380638
143288459	143288483	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGGCGCCGAGCGCGGGGTCTTGG	CASP2	ENSG00000106144	1.0126790762174267	[1649,923,1200]	[0,0,0]	2	hSpCas9	positive selection	2381771
143288459	143288483	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGGCGCCGAGCGCGGGGTCTTGG	CASP2	ENSG00000106144	1.0126790762174267	[1649,923,1200]	[0,0,0]	2	hSpCas9	positive selection	2381772
143291577	143291602	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAAACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	1.8035920520202813	[1398,1919,1707]	[0,4,0]	4	hSpCas9	positive selection	2381773
143291577	143291602	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAAACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	1.8035920520202813	[1398,1919,1707]	[0,4,0]	4	hSpCas9	positive selection	2381774
143288501	143288524	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	1.2202187360324042	[1115,1165,961]	[0,0,0]	3	hSpCas9	positive selection	2381775
143288501	143288524	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	1.2202187360324042	[1115,1165,961]	[0,0,0]	3	hSpCas9	positive selection	2381776
143289424	143289447	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTCAGTAAGTTGCAAGTATGG	CASP2	ENSG00000106144	-2.1575822234848676	[245,22]	[3,7]	-9	dCas9-VP64	positive selection	2413030
143289470	143289493	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGAAGGGGCGTCCCTAATGG	CASP2	ENSG00000106144	-0.24431561165387072	[178,371]	[88,9]	-1	dCas9-VP64	positive selection	2413031
143289445	143289468	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTGAGATTGTCTAGGGAAAGG	CASP2	ENSG00000106144	1.768016592064888	[111,34]	[20,90]	6	dCas9-VP64	positive selection	2413032
143289424	143289447	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTCAGTAAGTTGCAAGTATGG	CASP2	ENSG00000106144	-0.525031046602755	[60,38]	[16,5]	-5	dCas9-VP64	positive selection	2508285
143289470	143289493	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGAAGGGGCGTCCCTAATGG	CASP2	ENSG00000106144	-0.471983770649233	[61,152]	[23,24]	-5	dCas9-VP64	positive selection	2508286
143289445	143289468	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTGAGATTGTCTAGGGAAAGG	CASP2	ENSG00000106144	1.6516758510010163	[92,44]	[53,88]	8	dCas9-VP64	positive selection	2508287
143288479	143288502	7	+	27013184	SW480	treatment with recombinant TRAIL	TTGGTCCACCTTCCAGCACAAGG	CASP2	ENSG00000106144	0.14157934884669787	[361,629]	[189,287]	0	hSpCas9	positive selection	2957257
143291627	143291650	7	+	27013184	SW480	treatment with recombinant TRAIL	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	0.6379260641164215	[67,28]	[48,11]	3	hSpCas9	positive selection	2957258
143291633	143291656	7	+	27013184	SW480	treatment with recombinant TRAIL	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.47131490762365136	[236,186]	[83,190]	2	hSpCas9	positive selection	2957259
143291648	143291671	7	+	27013184	SW480	treatment with recombinant TRAIL	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	1.2060580497770652	[798,941]	[849,874]	5	hSpCas9	positive selection	2957260
143291656	143291679	7	+	27013184	SW480	treatment with recombinant TRAIL	ACATCATCACCTTGGAAATGAGG	CASP2	ENSG00000106144	0.407443751782135	[903,1133]	[590,557]	2	hSpCas9	positive selection	2957261
143291657	143291680	7	+	27013184	SW480	treatment with recombinant TRAIL	CATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	1.141433748953438	[107,224]	[219,58]	5	hSpCas9	positive selection	2957262
143292287	143292310	7	+	27013184	SW480	treatment with recombinant TRAIL	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.30487450869502297	[288,653]	[59,299]	-1	hSpCas9	positive selection	2957263
143292288	143292311	7	+	27013184	SW480	treatment with recombinant TRAIL	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	1.001934129940679	[929,1260]	[782,1148]	5	hSpCas9	positive selection	2957264
143288499	143288522	7	+	27013184	SW480	treatment with recombinant TRAIL	AGGAGCTGATGGCCGCTGACAGG	CASP2	ENSG00000106144	-0.6832076675845198	[731,593]	[282,32]	-3	hSpCas9	positive selection	2957265
143292308	143292331	7	+	27013184	SW480	treatment with recombinant TRAIL	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.7262287510831524	[28,56]	[9,57]	3	hSpCas9	positive selection	2957266
143292334	143292357	7	+	27013184	SW480	treatment with recombinant TRAIL	TCCTCAACTTGCTGCCTAAGAGG	CASP2	ENSG00000106144	0.2537469839849671	[456,854]	[294,375]	1	hSpCas9	positive selection	2957267
143292335	143292358	7	+	27013184	SW480	treatment with recombinant TRAIL	CCTCAACTTGCTGCCTAAGAGGG	CASP2	ENSG00000106144	-0.5150218054340536	[902,1134]	[219,424]	-2	hSpCas9	positive selection	2957268
143292336	143292359	7	+	27013184	SW480	treatment with recombinant TRAIL	CTCAACTTGCTGCCTAAGAGGGG	CASP2	ENSG00000106144	-0.053571327506722444	[347,331]	[132,153]	0	hSpCas9	positive selection	2957269
143291519	143291542	7	-	27013184	SW480	treatment with recombinant TRAIL	TCCTACAGATAAACGGTAGAAGG	CASP2	ENSG00000106144	0.7367216052449261	[172,98]	[107,88]	3	hSpCas9	positive selection	2957270
143288500	143288523	7	+	27013184	SW480	treatment with recombinant TRAIL	GGAGCTGATGGCCGCTGACAGGG	CASP2	ENSG00000106144	1.6513608692145023	[44,99]	[56,148]	7	hSpCas9	positive selection	2957271
143291526	143291549	7	-	27013184	SW480	treatment with recombinant TRAIL	CCCAATATCCTACAGATAAACGG	CASP2	ENSG00000106144	2.1325041571599535	[115,154]	[229,285]	8	hSpCas9	positive selection	2957272
143291594	143291617	7	-	27013184	SW480	treatment with recombinant TRAIL	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-0.6584292985654507	[546,308]	[161,59]	-3	hSpCas9	positive selection	2957273
143291608	143291631	7	-	27013184	SW480	treatment with recombinant TRAIL	TTCGCTCAACAACAGCTGTTTGG	CASP2	ENSG00000106144	-3.1361390605697386	[162,338]	[13,8]	-9	hSpCas9	positive selection	2957274
143291687	143291710	7	-	27013184	SW480	treatment with recombinant TRAIL	CTCTTTTGCCTCCAGATACCTGG	CASP2	ENSG00000106144	0.2584417126123797	[54,30]	[4,47]	1	hSpCas9	positive selection	2957275
143292301	143292324	7	-	27013184	SW480	treatment with recombinant TRAIL	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	-3.8682202705975834	[119,3257]	[32,63]	-9	hSpCas9	positive selection	2957276
143292320	143292343	7	-	27013184	SW480	treatment with recombinant TRAIL	AGTTGAGGAGTTCCACATTCTGG	CASP2	ENSG00000106144	-0.09645042338605014	[91,104]	[15,72]	0	hSpCas9	positive selection	2957277
143292335	143292358	7	-	27013184	SW480	treatment with recombinant TRAIL	CCCTCTTAGGCAGCAAGTTGAGG	CASP2	ENSG00000106144	-1.0552981847855063	[229,175]	[14,81]	-5	hSpCas9	positive selection	2957278
143292348	143292371	7	-	27013184	SW480	treatment with recombinant TRAIL	AAAGCTTGGGGACCCCTCTTAGG	CASP2	ENSG00000106144	1.4806857632334212	[143,290]	[140,414]	6	hSpCas9	positive selection	2957279
143288501	143288524	7	+	27013184	SW480	treatment with recombinant TRAIL	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	2.6813284424078194	[389,579]	[1307,1334]	9	hSpCas9	positive selection	2957280
143292362	143292385	7	-	27013184	SW480	treatment with recombinant TRAIL	CACAGAAGGCATCAAAAGCTTGG	CASP2	ENSG00000106144	-0.4550381167200388	[119,95]	[42,21]	-2	hSpCas9	positive selection	2957281
143291518	143291541	7	+	27013184	SW480	treatment with recombinant TRAIL	TCCTTCTACCGTTTATCTGTAGG	CASP2	ENSG00000106144	1.3018923560483688	[265,342]	[328,307]	6	hSpCas9	positive selection	2957282
143291525	143291548	7	+	27013184	SW480	treatment with recombinant TRAIL	ACCGTTTATCTGTAGGATATTGG	CASP2	ENSG00000106144	1.4658087654924898	[9,14]	[19,6]	6	hSpCas9	positive selection	2957283
143291526	143291549	7	+	27013184	SW480	treatment with recombinant TRAIL	CCGTTTATCTGTAGGATATTGGG	CASP2	ENSG00000106144	-0.11877146659466797	[50,141]	[18,61]	0	hSpCas9	positive selection	2957284
143291555	143291578	7	+	27013184	SW480	treatment with recombinant TRAIL	TGGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	-0.8353645927252723	[464,462]	[84,150]	-4	hSpCas9	positive selection	2957285
143291579	143291602	7	+	27013184	SW480	treatment with recombinant TRAIL	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.7516553033528943	[10,70]	[8,10]	-3	hSpCas9	positive selection	2957286
143291580	143291603	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.018036056740505825	[3,3]	[3,2]	0	hSpCas9	positive selection	2976407
143291594	143291617	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-0.0250706476626002	[3,3]	[2,3]	0	hSpCas9	positive selection	2976408
143288453	143288476	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	-0.16518440462325634	[2,2]	[3,0]	-2	hSpCas9	positive selection	2976409
143288511	143288534	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.3179219871299054	[3,3]	[3,3]	6	hSpCas9	positive selection	2976410
143291580	143291603	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.11758444596345557	[3,3]	[3,1]	2	hSpCas9	positive selection	3044265
143291594	143291617	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-0.2946812992084185	[3,3]	[4,0]	-4	hSpCas9	positive selection	3044266
143288453	143288476	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	-0.6665647849746272	[2,2]	[1,0]	-8	hSpCas9	positive selection	3044267
143288511	143288534	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	-0.2402594475322069	[3,3]	[4,0]	-4	hSpCas9	positive selection	3044268
143294713	143294736		+	24336571	A375	resistance to PLX after 7 days	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.2161140065306287	[13,14]	[17,14]	6	hSpCas9	positive selection	3160720
143299986	143300009		+	24336571	A375	resistance to PLX after 7 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.15991660470077568	[11,12]	[9,11]	-5	hSpCas9	positive selection	3160721
143291627	143291650		+	24336571	A375	resistance to PLX after 7 days	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.2393261992302318	[5,4]	[4,3]	-7	hSpCas9	positive selection	3160722
143292301	143292324		-	24336571	A375	resistance to PLX after 7 days	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	-0.277990369392759	[18,21]	[16,16]	-7	hSpCas9	positive selection	3160724
143299955	143299978		+	24336571	A375	resistance to PLX after 7 days	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	0.0748736486883973	[7,7]	[7,7]	2	hSpCas9	positive selection	3160725
143294752	143294775		+	24336571	A375	resistance to PLX after 7 days	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	0.18028675541010108	[15,16]	[17,18]	5	hSpCas9	positive selection	3160726
143291535	143291558		+	24336571	A375	resistance to PLX after 7 days	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.4842569618962097	[21,19]	[29,28]	9	hSpCas9	positive selection	3160727
143294713	143294736		+	24336571	A375	resistance to PLX after 14 days	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.9466021273836813	[13,10]	[9,11]	7	hSpCas9	positive selection	3218513
143299986	143300009		+	24336571	A375	resistance to PLX after 14 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.04923318173716723	[11,7]	[4,2]	0	hSpCas9	positive selection	3218514
143291627	143291650		+	24336571	A375	resistance to PLX after 14 days	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	0.6903098751892984	[3,1]	[1,2]	6	hSpCas9	positive selection	3218515
143292301	143292324		-	24336571	A375	resistance to PLX after 14 days	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	-1.0915965330744009	[19,26]	[5,3]	-9	hSpCas9	positive selection	3218517
143299955	143299978		+	24336571	A375	resistance to PLX after 14 days	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	-0.2496360880578838	[9,10]	[3,3]	-3	hSpCas9	positive selection	3218518
143294752	143294775		+	24336571	A375	resistance to PLX after 14 days	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	-0.45978032475805786	[16,10]	[4,3]	-5	hSpCas9	positive selection	3218519
143291535	143291558		+	24336571	A375	resistance to PLX after 14 days	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	3.027867115060616	[14,17]	[57,71]	9	hSpCas9	positive selection	3218520
143294713	143294736		+	24336571	A375	viability after 7 days	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.07595163698877701	[13]	[13,14]	1	hSpCas9	negative selection	3276306
143299986	143300009		+	24336571	A375	viability after 7 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.022584595609833374	[13]	[11,12]	0	hSpCas9	negative selection	3276307
143291627	143291650		+	24336571	A375	viability after 7 days	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.08360535589755669	[5]	[5,4]	-1	hSpCas9	negative selection	3276308
143292301	143292324		-	24336571	A375	viability after 7 days	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	0.445266510482922	[15]	[18,21]	6	hSpCas9	negative selection	3276310
143299955	143299978		+	24336571	A375	viability after 7 days	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	-0.2757530429334896	[9]	[7,7]	-4	hSpCas9	negative selection	3276311
143294752	143294775		+	24336571	A375	viability after 7 days	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	-0.49925190643084105	[23]	[15,16]	-6	hSpCas9	negative selection	3276312
143291535	143291558		+	24336571	A375	viability after 7 days	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.21975683734872947	[18]	[21,19]	3	hSpCas9	negative selection	3276313
143294713	143294736		+	24336571	A375	viability after 14 days	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	-0.12054645797718991	[13]	[13,10]	-1	hSpCas9	negative selection	3334099
143299986	143300009		+	24336571	A375	viability after 14 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	-0.31488314933058337	[13]	[11,7]	-4	hSpCas9	negative selection	3334100
143291627	143291650		+	24336571	A375	viability after 14 days	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.8622532449339868	[5]	[3,1]	-8	hSpCas9	negative selection	3334101
143292301	143292324		-	24336571	A375	viability after 14 days	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	0.6358609212983324	[15]	[19,26]	7	hSpCas9	negative selection	3334103
143299955	143299978		+	24336571	A375	viability after 14 days	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	0.14588311695425404	[9]	[9,10]	2	hSpCas9	negative selection	3334104
143294752	143294775		+	24336571	A375	viability after 14 days	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	-0.7021231471493757	[23]	[16,10]	-7	hSpCas9	negative selection	3334105
143291535	143291558		+	24336571	A375	viability after 14 days	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	-0.09077870994423304	[18]	[14,17]	-1	hSpCas9	negative selection	3334106
143299986	143300009	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.19412501827483009	[92,174]	[0,0]	1	hSpCas9	positive selection	3341118
143299967	143299990	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.014245591185399444	[149,152]	[0,0]	0	hSpCas9	positive selection	3341119
143294666	143294689	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	2.331699053255731	[13,46]	[0,0]	8	hSpCas9	positive selection	3341120
143294713	143294736	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	-1.9324983474341821	[583,583]	[0,0]	-9	hSpCas9	positive selection	3360366
143300260	143300283	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	-1.0914019427852424	[325,325]	[0,0]	-7	hSpCas9	positive selection	3360367
143300283	143300306	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.3746831620839938	[117,117]	[0,0]	2	hSpCas9	positive selection	3360368
143291579	143291602	7	+	26780180	HT29	viability (Avana library 4 designs)	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.87214705399059	[]	[]	3	hSpCas9	negative selection	3412688
143291594	143291617	7	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.283788183041613	[]	[]	1	hSpCas9	negative selection	3412689
143288452	143288475	7	+	26780180	HT29	viability (Avana library 4 designs)	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	0.546621219574625	[]	[]	2	hSpCas9	negative selection	3412690
143288511	143288534	7	-	26780180	HT29	viability (Avana library 4 designs)	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.125970510911956	[]	[]	0	hSpCas9	negative selection	3412691
143288511	143288534	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	6.0349465284446	[]	[]	9	hSpCas9	negative selection	3488280
143291594	143291617	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	6.16908234557124	[]	[]	9	hSpCas9	negative selection	3488281
143291579	143291602	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-10.528522938761	[]	[]	-8	hSpCas9	negative selection	3488282
143288452	143288475	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	7.35530485330837	[]	[]	9	hSpCas9	negative selection	3488283
143288487	143288510	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAGCTCCTTGTGCTGGAAGG	CASP2	ENSG00000106144	4.78424649868304	[]	[]	7	hSpCas9	negative selection	3488284
143291535	143291558	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	5.22082166994172	[]	[]	8	hSpCas9	negative selection	3488285
143288511	143288534	7	-	26780180	A375	viability (Avana lentiGuide)	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	-0.994699311795683	[]	[]	-1	hSpCas9	negative selection	3596939
143291594	143291617	7	-	26780180	A375	viability (Avana lentiGuide)	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-1.6795165962038	[]	[]	-3	hSpCas9	negative selection	3596940
143291579	143291602	7	+	26780180	A375	viability (Avana lentiGuide)	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-2.44586468082229	[]	[]	-4	hSpCas9	negative selection	3596941
143288452	143288475	7	+	26780180	A375	viability (Avana lentiGuide)	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	-0.398964277367249	[]	[]	0	hSpCas9	negative selection	3596942
143288487	143288510	7	-	26780180	A375	viability (Avana lentiGuide)	CATCAGCTCCTTGTGCTGGAAGG	CASP2	ENSG00000106144	1.58880140755806	[]	[]	1	hSpCas9	negative selection	3596943
143291535	143291558	7	+	26780180	A375	viability (Avana lentiGuide)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	-4.14276964190991	[]	[]	-7	hSpCas9	negative selection	3596944
143288511	143288534	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.25539064889391966	[5]	[6,5]	7	hSpCas9	positive selection	3705598
143291594	143291617	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.2833860730620188	[4]	[5,5]	7	hSpCas9	positive selection	3705599
143291579	143291602	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.4085788424619085	[5]	[3,4]	-6	hSpCas9	positive selection	3705600
143288452	143288475	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	0.38401561166437276	[3]	[4,5]	9	hSpCas9	positive selection	3705601
143288487	143288510	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAGCTCCTTGTGCTGGAAGG	CASP2	ENSG00000106144	0.2605521754600894	[5]	[6,5]	7	hSpCas9	positive selection	3705602
143291535	143291558	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.17215959195585992	[5]	[5,6]	5	hSpCas9	positive selection	3705603
143288511	143288534	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	-0.14115768913390872	[5]	[4,4]	-2	hSpCas9	positive selection	3814205
143291594	143291617	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-0.07697590082217115	[5]	[2,5]	-1	hSpCas9	positive selection	3814206
143291579	143291602	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.3213568627028567	[4]	[6,4]	8	hSpCas9	positive selection	3814207
143288452	143288475	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAATGGCGGCGCCGAGCGCGG	CASP2	ENSG00000106144	-0.06379335817018494	[3]	[3,1]	-1	hSpCas9	positive selection	3814208
143288487	143288510	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAGCTCCTTGTGCTGGAAGG	CASP2	ENSG00000106144	0.21399317576973984	[5]	[4,5]	5	hSpCas9	positive selection	3814209
143291535	143291558	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.3668339237566737	[6]	[7,6]	9	hSpCas9	positive selection	3814210
143294666	143294689	7	+	26780180	A375	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.871496065526573	[]	[]	3	hSpCas9	negative selection	3922505
143300260	143300283	7	+	26780180	A375	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.646506398006303	[]	[]	2	hSpCas9	negative selection	3922506
143300283	143300306	7	-	26780180	A375	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	1.55097733490054	[]	[]	8	hSpCas9	negative selection	3922507
143294713	143294736	7	+	26780180	A375	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	-0.190761466618503	[]	[]	-5	hSpCas9	negative selection	3922508
143299986	143300009	7	+	26780180	A375	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.852821477300261	[]	[]	3	hSpCas9	negative selection	3922509
143299967	143299990	7	-	26780180	A375	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	1.26701269894134	[]	[]	7	hSpCas9	negative selection	3922510
143294666	143294689	7	+	26780180	HT29	viability (GeCKOv2 library)	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.780271646806682	[]	[]	3	hSpCas9	negative selection	4030471
143300260	143300283	7	+	26780180	HT29	viability (GeCKOv2 library)	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.234792743628227	[]	[]	0	hSpCas9	negative selection	4030472
143300283	143300306	7	-	26780180	HT29	viability (GeCKOv2 library)	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	1.50274603621688	[]	[]	7	hSpCas9	negative selection	4030473
143294713	143294736	7	+	26780180	HT29	viability (GeCKOv2 library)	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.137842560567877	[]	[]	0	hSpCas9	negative selection	4030474
143299986	143300009	7	+	26780180	HT29	viability (GeCKOv2 library)	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.581384702775966	[]	[]	2	hSpCas9	negative selection	4030475
143299967	143299990	7	-	26780180	HT29	viability (GeCKOv2 library)	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	1.39263908663328	[]	[]	7	hSpCas9	negative selection	4030476
143294713	143294736	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.17108804533089592	[4]	[2,3]	4	hSpCas9	positive selection	4188813
143299986	143300009	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.0648432726470621	[3]	[2,1]	1	hSpCas9	positive selection	4188814
143291627	143291650	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.478946109666762	[2]	[0,0]	-8	hSpCas9	positive selection	4188815
143292301	143292324	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	-0.25896695858352614	[4]	[2,2]	-6	hSpCas9	positive selection	4188817
143299955	143299978	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	0.13384760957041314	[3]	[2,1]	3	hSpCas9	positive selection	4188818
143294752	143294775	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	-0.027290142045193727	[4]	[3,1]	0	hSpCas9	positive selection	4188819
143291535	143291558	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.4997752281780663	[4]	[3,5]	9	hSpCas9	positive selection	4188820
143294713	143294736	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4128345263576271	[4]	[4,4,4,0]	3	hSpCas9	positive selection	4252835
143299986	143300009	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5450389237101985	[3]	[4,3,3,0]	4	hSpCas9	positive selection	4252836
143291627	143291650	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAATTGTTAGAACATCTTCTGG	CASP2	ENSG00000106144	-0.6823792581552631	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4252837
143292301	143292324	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGCTGAAACTGCCCACTTTGG	CASP2	ENSG00000106144	0.5225908235842811	[3]	[0,4,6,0]	3	hSpCas9	positive selection	4252839
143299955	143299978	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACCTGCACACCGAGTCACGG	CASP2	ENSG00000106144	1.633487983196607	[2]	[0,3,2,4]	9	hSpCas9	positive selection	4252840
143294752	143294775	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTATGTGACCAGACTGCACAGG	CASP2	ENSG00000106144	0.5872172967838687	[4]	[1,2,0,3]	4	hSpCas9	positive selection	4252841
143291535	143291558	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAGGATATTGGGAGTGTGTGG	CASP2	ENSG00000106144	0.16033849029797986	[3]	[3,3,1,0]	1	hSpCas9	positive selection	4252842
143299986	143300009	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.26609113004245094	[2]	[3,2]	5	hSpCas9	positive selection	4261006
143299967	143299990	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.4202158170082356	[3]	[2,0]	-7	hSpCas9	positive selection	4261007
143294666	143294689	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.12482570166833684	[1]	[1,0]	2	hSpCas9	positive selection	4261008
143294713	143294736	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.6393972849743279	[3]	[5,4]	9	hSpCas9	positive selection	4325284
143300260	143300283	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5484193853530884	[3]	[3,4]	9	hSpCas9	positive selection	4325285
143300283	143300306	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	-0.9113971419386431	[2]	[0,0]	-9	hSpCas9	positive selection	4325286
143291556	143291578	7	+	27760321	OCIAML3	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.29834986345183295	[604,521]	[470,630]	3	hSpCas9	negative selection	4385794
143291580	143291602	7	+	27760321	OCIAML3	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.609938537159894	[86,70]	[51,24]	-5	hSpCas9	negative selection	4385795
143291594	143291616	7	-	27760321	OCIAML3	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.33278997862929516	[496,503]	[536,439]	4	hSpCas9	negative selection	4385796
143291658	143291680	7	+	27760321	OCIAML3	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.693044427441661	[251,214]	[226,381]	7	hSpCas9	negative selection	4385797
143292288	143292310	7	+	27760321	OCIAML3	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.08564722081053552	[399,339]	[210,350]	-1	hSpCas9	negative selection	4385798
143292678	143292700	7	+	27760321	OCIAML3	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	1.1310268217630193	[562,480]	[968,789]	9	hSpCas9	negative selection	4385799
143291556	143291578	7	+	27760321	OCIAML2	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.7527024860852845	[604,521]	[604,977]	8	hSpCas9	negative selection	4469257
143291580	143291602	7	+	27760321	OCIAML2	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.04313437974876466	[86,70]	[40,88]	0	hSpCas9	negative selection	4469258
143291594	143291616	7	-	27760321	OCIAML2	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.779581595662604	[496,503]	[550,890]	9	hSpCas9	negative selection	4469259
143291658	143291680	7	+	27760321	OCIAML2	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.41996182481193195	[251,214]	[244,260]	6	hSpCas9	negative selection	4469260
143292288	143292310	7	+	27760321	OCIAML2	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.4811086986643217	[399,339]	[339,516]	6	hSpCas9	negative selection	4469261
143292678	143292700	7	+	27760321	OCIAML2	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.26669587682077567	[562,480]	[445,585]	3	hSpCas9	negative selection	4469262
143291556	143291578	7	+	27760321	MV411	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	-0.08244285007724794	[604,521]	[386,294]	0	hSpCas9	negative selection	4552720
143291580	143291602	7	+	27760321	MV411	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	1.0581469431670114	[86,70]	[115,95]	7	hSpCas9	negative selection	4552721
143291594	143291616	7	-	27760321	MV411	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.8763073096355818	[496,503]	[638,562]	6	hSpCas9	negative selection	4552722
143291658	143291680	7	+	27760321	MV411	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	-0.2675719301511852	[251,214]	[115,144]	-2	hSpCas9	negative selection	4552723
143292288	143292310	7	+	27760321	MV411	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.90186663240966	[399,339]	[546,315]	6	hSpCas9	negative selection	4552724
143292678	143292700	7	+	27760321	MV411	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	-0.35758500379916264	[562,480]	[263,273]	-3	hSpCas9	negative selection	4552725
143291556	143291578	7	+	27760321	HL60	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.3011920714428716	[604,521]	[618,508]	4	hSpCas9	negative selection	4636183
143291580	143291602	7	+	27760321	HL60	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.6631363106809016	[86,70]	[8,73]	-6	hSpCas9	negative selection	4636184
143291594	143291616	7	-	27760321	HL60	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.6119645261716004	[496,503]	[602,652]	7	hSpCas9	negative selection	4636185
143291658	143291680	7	+	27760321	HL60	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.6060073050485187	[251,214]	[185,398]	7	hSpCas9	negative selection	4636186
143292288	143292310	7	+	27760321	HL60	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.1291318159884429	[399,339]	[293,366]	1	hSpCas9	negative selection	4636187
143292678	143292700	7	+	27760321	HL60	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.5275174362967406	[562,480]	[635,587]	6	hSpCas9	negative selection	4636188
143291556	143291578	7	+	27760321	HT1080	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	1.3586685687600166	[521,407]	[592,345]	7	hSpCas9	negative selection	4719646
143291580	143291602	7	+	27760321	HT1080	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	2.291211181008426	[70,55]	[184,56]	9	hSpCas9	negative selection	4719647
143291594	143291616	7	-	27760321	HT1080	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	1.5838120616989646	[503,392]	[641,418]	8	hSpCas9	negative selection	4719648
143291658	143291680	7	+	27760321	HT1080	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	1.0101267422911608	[214,167]	[135,172]	5	hSpCas9	negative selection	4719649
143292288	143292310	7	+	27760321	HT1080	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.2115542007603743	[339,265]	[166,109]	1	hSpCas9	negative selection	4719650
143292678	143292700	7	+	27760321	HT1080	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.7924818838462755	[480,375]	[225,371]	4	hSpCas9	negative selection	4719651
143291556	143291578	7	+	27760321	HT29	viability after 7 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.28512851596663574	[521,407]	[627,835,706]	4	hSpCas9	negative selection	4803109
143291580	143291602	7	+	27760321	HT29	viability after 7 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.7419383340907015	[70,55]	[118,36,1]	-8	hSpCas9	negative selection	4803110
143291594	143291616	7	-	27760321	HT29	viability after 7 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	-0.008818136116175157	[503,392]	[591,582,546]	0	hSpCas9	negative selection	4803111
143291658	143291680	7	+	27760321	HT29	viability after 7 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.6375604837081362	[214,167]	[532,348,290]	8	hSpCas9	negative selection	4803112
143292288	143292310	7	+	27760321	HT29	viability after 7 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.2710956207011077	[339,265]	[402,329,248]	-4	hSpCas9	negative selection	4803113
143292678	143292700	7	+	27760321	HT29	viability after 7 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.2502665531138017	[480,375]	[821,769,404]	4	hSpCas9	negative selection	4803114
143291556	143291578	7	+	27760321	HT29	viability after 25 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.2555502192758588	[521,407]	[470,683,771]	2	hSpCas9	negative selection	4886572
143291580	143291602	7	+	27760321	HT29	viability after 25 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.4553746708916049	[70,55]	[98,61,141]	5	hSpCas9	negative selection	4886573
143291594	143291616	7	-	27760321	HT29	viability after 25 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.4303681542550195	[503,392]	[679,559,847]	5	hSpCas9	negative selection	4886574
143291658	143291680	7	+	27760321	HT29	viability after 25 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.30279824879324735	[214,167]	[376,153,271]	3	hSpCas9	negative selection	4886575
143292288	143292310	7	+	27760321	HT29	viability after 25 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.0345904269814771	[339,265]	[311,317,390]	0	hSpCas9	negative selection	4886576
143292678	143292700	7	+	27760321	HT29	viability after 25 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.2528900749833272	[480,375]	[526,611,617]	2	hSpCas9	negative selection	4886577
143291556	143291578	7	+	27760321	HT29	viability after 22 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.5957796792803807	[521,407]	[693,790,956]	6	hSpCas9	negative selection	4970035
143291580	143291602	7	+	27760321	HT29	viability after 22 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.3985563680266808	[70,55]	[200,59,25]	4	hSpCas9	negative selection	4970036
143291594	143291616	7	-	27760321	HT29	viability after 22 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.5694004320891161	[503,392]	[804,736,764]	6	hSpCas9	negative selection	4970037
143291658	143291680	7	+	27760321	HT29	viability after 22 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	-0.11262044863313248	[214,167]	[189,189,234]	-1	hSpCas9	negative selection	4970038
143292288	143292310	7	+	27760321	HT29	viability after 22 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.7534495027335988	[339,265]	[773,592,397]	8	hSpCas9	negative selection	4970039
143292678	143292700	7	+	27760321	HT29	viability after 22 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.353934527216276	[480,375]	[478,856,566]	4	hSpCas9	negative selection	4970040
143291556	143291578	7	+	27760321	HT29	viability after 19 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.4313270230896809	[521,407]	[664,531,939]	4	hSpCas9	negative selection	5053498
143291580	143291602	7	+	27760321	HT29	viability after 19 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.44228100351877897	[70,55]	[103,42,19]	-4	hSpCas9	negative selection	5053499
143291594	143291616	7	-	27760321	HT29	viability after 19 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.49486009422988175	[503,392]	[541,724,875]	5	hSpCas9	negative selection	5053500
143291658	143291680	7	+	27760321	HT29	viability after 19 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.5932542976613587	[214,167]	[291,469,228]	6	hSpCas9	negative selection	5053501
143292288	143292310	7	+	27760321	HT29	viability after 19 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.07764748268363525	[339,265]	[533,385,200]	0	hSpCas9	negative selection	5053502
143292678	143292700	7	+	27760321	HT29	viability after 19 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.6314240020603699	[480,375]	[784,1006,497]	6	hSpCas9	negative selection	5053503
143291556	143291578	7	+	27760321	HT29	viability after 16 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.1333706172761105	[521,407]	[562,502,646]	1	hSpCas9	negative selection	5136961
143291580	143291602	7	+	27760321	HT29	viability after 16 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.030281038293277884	[70,55]	[13,129,57]	0	hSpCas9	negative selection	5136962
143291594	143291616	7	-	27760321	HT29	viability after 16 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.36200503274433504	[503,392]	[783,553,611]	4	hSpCas9	negative selection	5136963
143291658	143291680	7	+	27760321	HT29	viability after 16 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.444238780766264	[214,167]	[235,302,329]	5	hSpCas9	negative selection	5136964
143292288	143292310	7	+	27760321	HT29	viability after 16 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.3608263203490884	[339,265]	[387,382,531]	4	hSpCas9	negative selection	5136965
143292678	143292700	7	+	27760321	HT29	viability after 16 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.39911999322229547	[480,375]	[588,807,490]	4	hSpCas9	negative selection	5136966
143291556	143291578	7	+	27760321	HT29	viability after 13 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.25101092103130457	[521,407]	[704,530,686]	3	hSpCas9	negative selection	5220424
143291580	143291602	7	+	27760321	HT29	viability after 13 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	0.16547755877579284	[70,55]	[101,80,65]	2	hSpCas9	negative selection	5220425
143291594	143291616	7	-	27760321	HT29	viability after 13 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.15860075479672475	[503,392]	[538,584,615]	2	hSpCas9	negative selection	5220426
143291658	143291680	7	+	27760321	HT29	viability after 13 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	-0.24996436210669837	[214,167]	[195,118,241]	-3	hSpCas9	negative selection	5220427
143292288	143292310	7	+	27760321	HT29	viability after 13 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.09566193119607022	[339,265]	[387,381,357]	1	hSpCas9	negative selection	5220428
143292678	143292700	7	+	27760321	HT29	viability after 13 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.3041705467604244	[480,375]	[981,439,429]	4	hSpCas9	negative selection	5220429
143291556	143291578	7	+	27760321	HT29	viability after 10 days	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	0.32175341231404536	[521,407]	[888,652,634]	4	hSpCas9	negative selection	5303887
143291580	143291602	7	+	27760321	HT29	viability after 10 days	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	-0.38151572305851156	[70,55]	[107,25,47]	-5	hSpCas9	negative selection	5303888
143291594	143291616	7	-	27760321	HT29	viability after 10 days	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	0.4083607868506798	[503,392]	[642,981,613]	5	hSpCas9	negative selection	5303889
143291658	143291680	7	+	27760321	HT29	viability after 10 days	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.6433654983966819	[214,167]	[220,232,655]	8	hSpCas9	negative selection	5303890
143292288	143292310	7	+	27760321	HT29	viability after 10 days	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.4277550334408393	[339,265]	[438,343,733]	6	hSpCas9	negative selection	5303891
143292678	143292700	7	+	27760321	HT29	viability after 10 days	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	0.04710040971591545	[480,375]	[706,596,359]	0	hSpCas9	negative selection	5303892
143291556	143291578	7	+	27760321	MOLM13	viability	GGCATGCATCCTCATCATCAGG	CASP2	ENSG00000106144	1.7059888824667468	[604,521]	[1405,717]	9	hSpCas9	negative selection	5387350
143291580	143291602	7	+	27760321	MOLM13	viability	ACTCTAAAAAAGAACCGAGTGG	CASP2	ENSG00000106144	1.45723163630321	[86,70]	[23,204]	8	hSpCas9	negative selection	5387351
143291594	143291616	7	-	27760321	MOLM13	viability	CTGTTTGGCTAGCACCACTCGG	CASP2	ENSG00000106144	1.1249839699119668	[496,503]	[809,454]	7	hSpCas9	negative selection	5387352
143291658	143291680	7	+	27760321	MOLM13	viability	ATCATCACCTTGGAAATGAGGG	CASP2	ENSG00000106144	0.8826425758648667	[251,214]	[132,334]	6	hSpCas9	negative selection	5387353
143292288	143292310	7	+	27760321	MOLM13	viability	CTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	1.6551656621815578	[399,339]	[227,1018]	9	hSpCas9	negative selection	5387354
143292678	143292700	7	+	27760321	MOLM13	viability	AGAAGCTCCGCCTGTCGACAGG	CASP2	ENSG00000106144	-0.24561268484401452	[562,480]	[245,248]	-2	hSpCas9	negative selection	5387355
143288412	143288435	7	+	27661255	K562	viability	GGGCTGTGGGCGGTGCGCAGCGG	CASP2	ENSG00000106144	0.01328622481405567	[986,931]	[877,685]	0	dCas9-KRAB	negative selection	5468204
143288431	143288454	7	+	27661255	K562	viability	GCGGAGAGCCCGGGAAAAGCGGG	CASP2	ENSG00000106144	-0.31678716638218196	[392,318]	[253,207]	-7	dCas9-KRAB	negative selection	5468205
143288501	143288524	7	+	27661255	K562	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.18099121268244223	[1042,1290]	[1035,1066]	6	dCas9-KRAB	negative selection	5468206
143288680	143288703	7	-	27661255	K562	viability	GCGCGGAGTCAGGCTCGGAGCGG	CASP2	ENSG00000106144	0.19193220453317172	[284,317]	[293,257]	6	dCas9-KRAB	negative selection	5468207
143299986	143300009	7	+	27260156	BXPC3	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6278877899606702	[435]	[508,569,832,964]	9	hSpCas9	negative selection	5533466
143299967	143299990	7	-	27260156	BXPC3	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.02105437597973092	[562]	[534,519,615,743]	0	hSpCas9	negative selection	5533467
143294666	143294689	7	+	27260156	BXPC3	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.14413882316437188	[120]	[78,72,140,178]	-3	hSpCas9	negative selection	5533468
143294713	143294736	7	+	27260156	BXPC3	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.43317075722723564	[955]	[1213,1329,1355,1526]	8	hSpCas9	negative selection	5597744
143300260	143300283	7	+	27260156	BXPC3	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.047080962638640256	[732]	[783,770,752,863]	1	hSpCas9	negative selection	5597745
143300283	143300306	7	-	27260156	BXPC3	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.5274897528851639	[213]	[294,254,338,417]	9	hSpCas9	negative selection	5597746
143299986	143300009	7	+	27260156	A673	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.44840154436117846	[435]	[784,739,701,631]	8	hSpCas9	negative selection	5654717
143299967	143299990	7	-	27260156	A673	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.04447851668099323	[562]	[691,564,694,675]	-1	hSpCas9	negative selection	5654718
143294666	143294689	7	+	27260156	A673	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.0014242558449606424	[120]	[129,167,149,128]	0	hSpCas9	negative selection	5654719
143294713	143294736	7	+	27260156	A673	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4367476493016811	[955]	[1596,1521,1759,1323]	8	hSpCas9	negative selection	5718995
143300260	143300283	7	+	27260156	A673	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.22826515104910838	[732]	[1105,1035,945,1043]	5	hSpCas9	negative selection	5718996
143300283	143300306	7	-	27260156	A673	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.29513714051472173	[213]	[371,295,325,270]	7	hSpCas9	negative selection	5718997
143299986	143300009	7	+	27260156	A375	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.31523612420325253	[435]	[458,705,725,647]	4	hSpCas9	negative selection	5775968
143299967	143299990	7	-	27260156	A375	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.06565342310374994	[562]	[565,627,850,694]	0	hSpCas9	negative selection	5775969
143294666	143294689	7	+	27260156	A375	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.13084681208461157	[120]	[104,330,83,125]	2	hSpCas9	negative selection	5775970
143294713	143294736	7	+	27260156	A375	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.659226112990347	[955]	[1784,2196,1656,1499]	8	hSpCas9	negative selection	5840246
143300260	143300283	7	+	27260156	A375	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.4287412593644352	[732]	[1295,1251,1214,888]	6	hSpCas9	negative selection	5840247
143300283	143300306	7	-	27260156	A375	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.00605083557017716	[213]	[274,260,165,296]	0	hSpCas9	negative selection	5840248
143299986	143300009	7	+	27260156	COLO741	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.3992013437239927	[435]	[877,556,775]	7	hSpCas9	negative selection	5897219
143299967	143299990	7	-	27260156	COLO741	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.15451075092469388	[562]	[777,463,701]	-3	hSpCas9	negative selection	5897220
143294666	143294689	7	+	27260156	COLO741	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.03635818299179516	[120]	[146,191,136]	0	hSpCas9	negative selection	5897221
143294713	143294736	7	+	27260156	COLO741	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4761728968531236	[955]	[2015,1615,1502]	8	hSpCas9	negative selection	5961497
143300260	143300283	7	+	27260156	COLO741	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.32442467780091644	[732]	[1048,1125,1318]	6	hSpCas9	negative selection	5961498
143300283	143300306	7	-	27260156	COLO741	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.3123663870814264	[213]	[443,333,254]	6	hSpCas9	negative selection	5961499
143299986	143300009	7	+	27260156	CAL120	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.30080823492846265	[435]	[900,652,488]	4	hSpCas9	negative selection	6018470
143299967	143299990	7	-	27260156	CAL120	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.26632980898183733	[562]	[1077,588,894]	4	hSpCas9	negative selection	6018471
143294666	143294689	7	+	27260156	CAL120	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.8216675297939009	[120]	[327,292,187]	9	hSpCas9	negative selection	6018472
143294713	143294736	7	+	27260156	CAL120	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4405657224138426	[955]	[1568,1709,1557]	6	hSpCas9	negative selection	6082748
143300260	143300283	7	+	27260156	CAL120	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5840847431047796	[732]	[1453,1707,959]	8	hSpCas9	negative selection	6082749
143300283	143300306	7	-	27260156	CAL120	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.5226685892007975	[213]	[552,338,282]	7	hSpCas9	negative selection	6082750
143299986	143300009	7	+	27260156	CADOES1	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.262034298984535	[435]	[545,475,408,514]	4	hSpCas9	negative selection	6139721
143299967	143299990	7	-	27260156	CADOES1	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.19985286253082438	[562]	[636,399,380,402]	-3	hSpCas9	negative selection	6139722
143294666	143294689	7	+	27260156	CADOES1	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.060348955369391666	[120]	[93,87,82,168]	-1	hSpCas9	negative selection	6139723
143294713	143294736	7	+	27260156	CADOES1	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.6161842851189607	[955]	[1180,1306,1366,1605]	8	hSpCas9	negative selection	6203999
143300260	143300283	7	+	27260156	CADOES1	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.6729299042249085	[732]	[1080,941,886,1450]	9	hSpCas9	negative selection	6204000
143300283	143300306	7	-	27260156	CADOES1	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.17707319153477097	[213]	[267,160,190,281]	3	hSpCas9	negative selection	6204001
143299986	143300009	7	+	27260156	EWS502	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.402782057253582	[435]	[542,607,624,676]	7	hSpCas9	negative selection	6260972
143299967	143299990	7	-	27260156	EWS502	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.0044345263984875705	[562]	[529,555,764,547]	0	hSpCas9	negative selection	6260973
143294666	143294689	7	+	27260156	EWS502	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.20330244932421082	[120]	[157,108,100,226]	3	hSpCas9	negative selection	6260974
143294713	143294736	7	+	27260156	EWS502	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.34726861212707116	[955]	[1104,1437,1257,1367]	6	hSpCas9	negative selection	6325250
143300260	143300283	7	+	27260156	EWS502	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5116253152771927	[732]	[1032,1039,1061,1313]	8	hSpCas9	negative selection	6325251
143300283	143300306	7	-	27260156	EWS502	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.23347577458095037	[213]	[343,228,237,243]	4	hSpCas9	negative selection	6325252
143299986	143300009	7	+	27260156	EW8	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.3366757862245267	[435]	[569,480,342,420]	6	hSpCas9	negative selection	6382223
143299967	143299990	7	-	27260156	EW8	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.2851810493835749	[562]	[713,664,501,368]	5	hSpCas9	negative selection	6382224
143294666	143294689	7	+	27260156	EW8	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.34284429133642935	[120]	[63,85,56,103]	-6	hSpCas9	negative selection	6382225
143294713	143294736	7	+	27260156	EW8	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.5543067131814803	[955]	[1373,1101,950,1177]	8	hSpCas9	negative selection	6446501
143300260	143300283	7	+	27260156	EW8	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.43322996982136297	[732]	[916,948,634,746]	7	hSpCas9	negative selection	6446502
143300283	143300306	7	-	27260156	EW8	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.19331319421384563	[213]	[180,279,193,136]	3	hSpCas9	negative selection	6446503
143299986	143300009	7	+	27260156	CORL105	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5445290269665635	[435]	[1001,572,805,618]	8	hSpCas9	negative selection	6503474
143299967	143299990	7	-	27260156	CORL105	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.09581349938934314	[562]	[680,675,824,653]	1	hSpCas9	negative selection	6503475
143294666	143294689	7	+	27260156	CORL105	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.20015293076611385	[120]	[113,180,276,94]	4	hSpCas9	negative selection	6503476
143294713	143294736	7	+	27260156	CORL105	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.46931212691612023	[955]	[1599,1568,1712,1342]	8	hSpCas9	negative selection	6567752
143300260	143300283	7	+	27260156	CORL105	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.08505063736227736	[732]	[904,906,1038,809]	1	hSpCas9	negative selection	6567753
143300283	143300306	7	-	27260156	CORL105	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.03319065728388626	[213]	[159,393,246,216]	0	hSpCas9	negative selection	6567754
143299986	143300009	7	+	27260156	HS294T	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5760877087943708	[435]	[175,252,239,360]	7	hSpCas9	negative selection	6624725
143299967	143299990	7	-	27260156	HS294T	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.5025854607302824	[562]	[248,442,226,315]	6	hSpCas9	negative selection	6624726
143294666	143294689	7	+	27260156	HS294T	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.16193754682308148	[120]	[72,50,41,38]	2	hSpCas9	negative selection	6624727
143294713	143294736	7	+	27260156	HS294T	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.8109433631621605	[955]	[816,610,492,656]	9	hSpCas9	negative selection	6689003
143300260	143300283	7	+	27260156	HS294T	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	-0.29478629170338144	[732]	[234,215,193,287]	-4	hSpCas9	negative selection	6689004
143300283	143300306	7	-	27260156	HS294T	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.10411340490613452	[213]	[78,76,115,83]	1	hSpCas9	negative selection	6689005
143299986	143300009	7	+	27260156	HCC44	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.9126417729181242	[435]	[984,876,1088,798]	9	hSpCas9	negative selection	6745976
143299967	143299990	7	-	27260156	HCC44	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.4215579843767705	[562]	[774,578,1358,811]	7	hSpCas9	negative selection	6745977
143294666	143294689	7	+	27260156	HCC44	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.03664882705630257	[120]	[101,189,142,115]	0	hSpCas9	negative selection	6745978
143294713	143294736	7	+	27260156	HCC44	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.438018357957787	[955]	[1332,1169,2243,1270]	7	hSpCas9	negative selection	6810254
143300260	143300283	7	+	27260156	HCC44	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.6928958822539389	[732]	[1921,1122,1685,780]	9	hSpCas9	negative selection	6810255
143300283	143300306	7	-	27260156	HCC44	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.3224499972652687	[213]	[355,219,350,305]	5	hSpCas9	negative selection	6810256
143299986	143300009	7	+	27260156	G402	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6094309194906978	[435]	[860,768,845,773]	7	hSpCas9	negative selection	6867227
143299967	143299990	7	-	27260156	G402	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.2441066893181576	[562]	[889,531,946,873]	3	hSpCas9	negative selection	6867228
143294666	143294689	7	+	27260156	G402	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.5838199069057455	[120]	[301,311,166,124]	7	hSpCas9	negative selection	6867229
143294713	143294736	7	+	27260156	G402	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	1.0370446401232503	[955]	[2689,1794,2238,2827]	9	hSpCas9	negative selection	6931505
143300260	143300283	7	+	27260156	G402	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.25853086162636196	[732]	[1091,1034,1444,721]	3	hSpCas9	negative selection	6931506
143300283	143300306	7	-	27260156	G402	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.5372356006376318	[213]	[312,243,371,558]	6	hSpCas9	negative selection	6931507
143299986	143300009	7	+	27260156	L33	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.7047972094111051	[435]	[680,301,358,851]	9	hSpCas9	negative selection	6988478
143299967	143299990	7	-	27260156	L33	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.26683854633602155	[562]	[615,308,450,623]	6	hSpCas9	negative selection	6988479
143294666	143294689	7	+	27260156	L33	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.12585650783399838	[120]	[101,58,113,101]	3	hSpCas9	negative selection	6988480
143294713	143294736	7	+	27260156	L33	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.26378949943314844	[955]	[1287,439,724,1072]	5	hSpCas9	negative selection	7052756
143300260	143300283	7	+	27260156	L33	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	-0.04207015294573768	[732]	[765,281,383,779]	-1	hSpCas9	negative selection	7052757
143300283	143300306	7	-	27260156	L33	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.32223641294799843	[213]	[278,83,220,234]	6	hSpCas9	negative selection	7052758
143299986	143300009	7	+	27260156	K562	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.8149039319680268	[435]	[622,881,807,440]	9	hSpCas9	negative selection	7109729
143299967	143299990	7	-	27260156	K562	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.48601108666511317	[562]	[752,1334,321,452]	6	hSpCas9	negative selection	7109730
143294666	143294689	7	+	27260156	K562	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.91229032516616	[120]	[125,508,70,120]	9	hSpCas9	negative selection	7109731
143294713	143294736	7	+	27260156	K562	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4416661767922576	[955]	[1490,1431,877,877]	5	hSpCas9	negative selection	7174007
143300260	143300283	7	+	27260156	K562	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5831599452559065	[732]	[1087,1084,1506,307]	7	hSpCas9	negative selection	7174008
143300283	143300306	7	-	27260156	K562	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.49848350149366427	[213]	[255,224,453,147]	6	hSpCas9	negative selection	7174009
143299986	143300009	7	+	27260156	HT29	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4239724468923288	[435]	[682,938,599,642]	7	hSpCas9	negative selection	7230980
143299967	143299990	7	-	27260156	HT29	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.12802691370941677	[562]	[1058,818,711,461]	2	hSpCas9	negative selection	7230981
143294666	143294689	7	+	27260156	HT29	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.039305159817388136	[120]	[90,158,185,133]	-1	hSpCas9	negative selection	7230982
143294713	143294736	7	+	27260156	HT29	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.44422469105315154	[955]	[1925,1723,1148,1555]	8	hSpCas9	negative selection	7295258
143300260	143300283	7	+	27260156	HT29	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.2995542679739194	[732]	[1266,1102,985,1042]	6	hSpCas9	negative selection	7295259
143300283	143300306	7	-	27260156	HT29	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.1987453006819585	[213]	[272,317,366,240]	4	hSpCas9	negative selection	7295260
143299986	143300009	7	+	27260156	MHHES1	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4835214556424914	[435]	[1034,1025,380,424]	8	hSpCas9	negative selection	7352231
143299967	143299990	7	-	27260156	MHHES1	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.10446689151863348	[562]	[550,717,787,649]	2	hSpCas9	negative selection	7352232
143294666	143294689	7	+	27260156	MHHES1	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.028044205951863077	[120]	[214,178,152,41]	0	hSpCas9	negative selection	7352233
143294713	143294736	7	+	27260156	MHHES1	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.6239012497945362	[955]	[2049,2067,1304,1337]	9	hSpCas9	negative selection	7416509
143300260	143300283	7	+	27260156	MHHES1	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.35962757836349646	[732]	[1247,1385,1021,697]	6	hSpCas9	negative selection	7416510
143300283	143300306	7	-	27260156	MHHES1	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.18381208984193964	[213]	[219,409,239,234]	3	hSpCas9	negative selection	7416511
143299986	143300009	7	+	27260156	MEWO	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5229137231277041	[435]	[803,459,536]	9	hSpCas9	negative selection	7473482
143299967	143299990	7	-	27260156	MEWO	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.29530643478873775	[562]	[952,513,531]	6	hSpCas9	negative selection	7473483
143294666	143294689	7	+	27260156	MEWO	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.06918295212472736	[120]	[149,74,106]	-1	hSpCas9	negative selection	7473484
143294713	143294736	7	+	27260156	MEWO	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.2522328341437712	[955]	[1344,1017,886]	5	hSpCas9	negative selection	7537760
143300260	143300283	7	+	27260156	MEWO	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.070462028140302	[732]	[951,523,729]	1	hSpCas9	negative selection	7537761
143300283	143300306	7	-	27260156	MEWO	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.049732770416675676	[213]	[232,133,259]	1	hSpCas9	negative selection	7537762
143299986	143300009	7	+	27260156	LNCAPCLONEFGC	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.17089024825232588	[435]	[574,304,431,470]	2	hSpCas9	negative selection	7594733
143299967	143299990	7	-	27260156	LNCAPCLONEFGC	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.16763285481090162	[562]	[462,440,530,392]	-3	hSpCas9	negative selection	7594734
143294666	143294689	7	+	27260156	LNCAPCLONEFGC	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.39531732169758715	[120]	[81,129,307,82]	6	hSpCas9	negative selection	7594735
143294713	143294736	7	+	27260156	LNCAPCLONEFGC	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.7710346172570661	[955]	[1219,1511,1753,1467]	9	hSpCas9	negative selection	7659011
143300260	143300283	7	+	27260156	LNCAPCLONEFGC	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.36847789481427606	[732]	[839,929,905,754]	6	hSpCas9	negative selection	7659012
143300283	143300306	7	-	27260156	LNCAPCLONEFGC	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.0009910136560753458	[213]	[231,155,216,175]	0	hSpCas9	negative selection	7659013
143299986	143300009	7	+	27260156	PANC0327	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.8956221811823996	[435]	[788,902,640,530]	9	hSpCas9	negative selection	7715984
143299967	143299990	7	-	27260156	PANC0327	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.249690571945282	[562]	[693,435,657,618]	3	hSpCas9	negative selection	7715985
143294666	143294689	7	+	27260156	PANC0327	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.4058857655629622	[120]	[89,74,180,227]	6	hSpCas9	negative selection	7715986
143294713	143294736	7	+	27260156	PANC0327	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.44256054822045354	[955]	[1223,1087,1013,1303]	6	hSpCas9	negative selection	7780262
143300260	143300283	7	+	27260156	PANC0327	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.382340252638795	[732]	[1196,525,930,810]	5	hSpCas9	negative selection	7780263
143300283	143300306	7	-	27260156	PANC0327	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.27096408863971955	[213]	[245,196,246,232]	4	hSpCas9	negative selection	7780264
143299986	143300009	7	+	27260156	NCIH2009	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5662824082492623	[435]	[1200,875,686]	7	hSpCas9	negative selection	7837235
143299967	143299990	7	-	27260156	NCIH2009	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.6604739431916745	[562]	[1804,1177,856]	8	hSpCas9	negative selection	7837236
143294666	143294689	7	+	27260156	NCIH2009	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.8020660574122616	[120]	[535,265,129]	9	hSpCas9	negative selection	7837237
143294713	143294736	7	+	27260156	NCIH2009	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4283447261620952	[955]	[1804,1779,1805]	6	hSpCas9	negative selection	7901513
143300260	143300283	7	+	27260156	NCIH2009	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.20922284973594385	[732]	[1533,1294,787]	3	hSpCas9	negative selection	7901514
143300283	143300306	7	-	27260156	NCIH2009	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.1016420580611237	[213]	[355,312,299]	1	hSpCas9	negative selection	7901515
143299986	143300009	7	+	27260156	NCIH1373	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.41157442450040643	[435]	[862,272,924,157]	4	hSpCas9	negative selection	7958486
143299967	143299990	7	-	27260156	NCIH1373	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.10916241089764	[562]	[556,846,422,228]	1	hSpCas9	negative selection	7958487
143294666	143294689	7	+	27260156	NCIH1373	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.40871513815580873	[120]	[120,179,179,60]	4	hSpCas9	negative selection	7958488
143294713	143294736	7	+	27260156	NCIH1373	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.9249587236744423	[955]	[2521,1534,1818,632]	8	hSpCas9	negative selection	8022764
143300260	143300283	7	+	27260156	NCIH1373	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.2454900385461215	[732]	[1429,1006,590,245]	2	hSpCas9	negative selection	8022765
143300283	143300306	7	-	27260156	NCIH1373	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.4190935629902738	[213]	[648,360,172,35]	4	hSpCas9	negative selection	8022766
143299986	143300009	7	+	27260156	PATU8902	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6890268937215818	[435]	[807,1453,509,1299]	7	hSpCas9	negative selection	8079737
143299967	143299990	7	-	27260156	PATU8902	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.7687016686921945	[562]	[1763,973,1146,1510]	7	hSpCas9	negative selection	8079738
143294666	143294689	7	+	27260156	PATU8902	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.22155468642919307	[120]	[15,148,22,459]	-2	hSpCas9	negative selection	8079739
143294713	143294736	7	+	27260156	PATU8902	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.8975292897954643	[955]	[1562,2944,2480,2985]	8	hSpCas9	negative selection	8144015
143300260	143300283	7	+	27260156	PATU8902	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.6320603279482798	[732]	[1622,2336,1344,1004]	6	hSpCas9	negative selection	8144016
143300283	143300306	7	-	27260156	PATU8902	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.34599945000473453	[213]	[433,196,437,432]	3	hSpCas9	negative selection	8144017
143299986	143300009	7	+	27260156	PANC1	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4135599565565369	[435]	[590,670,434,347]	6	hSpCas9	negative selection	8200988
143299967	143299990	7	-	27260156	PANC1	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.0961195417405262	[562]	[546,565,377,348]	-1	hSpCas9	negative selection	8200989
143294666	143294689	7	+	27260156	PANC1	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.03422331178602844	[120]	[77,109,127,108]	0	hSpCas9	negative selection	8200990
143294713	143294736	7	+	27260156	PANC1	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.5634927701190586	[955]	[1110,1867,1252,806]	8	hSpCas9	negative selection	8265266
143300260	143300283	7	+	27260156	PANC1	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5686039953786394	[732]	[890,1290,917,727]	8	hSpCas9	negative selection	8265267
143300283	143300306	7	-	27260156	PANC1	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.2595538636613224	[213]	[206,198,301,172]	4	hSpCas9	negative selection	8265268
143299986	143300009	7	+	27260156	PANC0813	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6391724374530744	[435]	[1101,621,781,715]	8	hSpCas9	negative selection	8322239
143299967	143299990	7	-	27260156	PANC0813	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.2595565350820851	[562]	[807,888,809,666]	4	hSpCas9	negative selection	8322240
143294666	143294689	7	+	27260156	PANC0813	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.6528294170517717	[120]	[259,287,135,212]	9	hSpCas9	negative selection	8322241
143294713	143294736	7	+	27260156	PANC0813	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4929322781081895	[955]	[2038,1306,1526,1492]	7	hSpCas9	negative selection	8386517
143300260	143300283	7	+	27260156	PANC0813	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.1418701043724585	[732]	[1368,843,898,736]	2	hSpCas9	negative selection	8386518
143300283	143300306	7	-	27260156	PANC0813	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.5814632884703143	[213]	[402,524,329,254]	8	hSpCas9	negative selection	8386519
143299986	143300009	7	+	27260156	RDES	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.24859805890886522	[435]	[562,485,555,806]	4	hSpCas9	negative selection	8443490
143299967	143299990	7	-	27260156	RDES	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.1921940771992739	[562]	[589,715,913,760]	3	hSpCas9	negative selection	8443491
143294666	143294689	7	+	27260156	RDES	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.09147166739451928	[120]	[110,166,180,134]	1	hSpCas9	negative selection	8443492
143294713	143294736	7	+	27260156	RDES	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.7520738731380157	[955]	[1502,1668,2062,2282]	9	hSpCas9	negative selection	8507768
143300260	143300283	7	+	27260156	RDES	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5121437885989976	[732]	[1020,1174,1203,1450]	7	hSpCas9	negative selection	8507769
143300283	143300306	7	-	27260156	RDES	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.7831818085392963	[213]	[293,400,345,712]	9	hSpCas9	negative selection	8507770
143299986	143300009	7	+	27260156	PC3	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.21796743687350087	[435]	[234,392,835,786]	5	hSpCas9	negative selection	8564741
143299967	143299990	7	-	27260156	PC3	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.15094735485027017	[562]	[327,404,805,638]	-3	hSpCas9	negative selection	8564742
143294666	143294689	7	+	27260156	PC3	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.30901622821765073	[120]	[139,103,142,195]	6	hSpCas9	negative selection	8564743
143294713	143294736	7	+	27260156	PC3	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.3595216506323671	[955]	[934,1078,1985,1177]	7	hSpCas9	negative selection	8629019
143300260	143300283	7	+	27260156	PC3	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.20873217789695142	[732]	[499,769,1535,921]	4	hSpCas9	negative selection	8629020
143300283	143300306	7	-	27260156	PC3	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.6022648418195466	[213]	[270,249,491,334]	9	hSpCas9	negative selection	8629021
143299986	143300009	7	+	27260156	PATU8988T	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5806780326232873	[435]	[441,734,650,707]	8	hSpCas9	negative selection	8685992
143299967	143299990	7	-	27260156	PATU8988T	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.0006549336998833422	[562]	[575,542,428,637]	0	hSpCas9	negative selection	8685993
143294666	143294689	7	+	27260156	PATU8988T	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.5946614830366281	[120]	[59,294,206,152]	8	hSpCas9	negative selection	8685994
143294713	143294736	7	+	27260156	PATU8988T	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.497070056148877	[955]	[1269,1626,1161,1177]	8	hSpCas9	negative selection	8750270
143300260	143300283	7	+	27260156	PATU8988T	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.2772845211591177	[732]	[885,935,673,954]	5	hSpCas9	negative selection	8750271
143300283	143300306	7	-	27260156	PATU8988T	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.5697223942808052	[213]	[254,266,292,417]	8	hSpCas9	negative selection	8750272
143299986	143300009	7	+	27260156	T47D	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.401273144857411	[435]	[787,539,807,552]	8	hSpCas9	negative selection	8807243
143299967	143299990	7	-	27260156	T47D	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.04701003846197155	[562]	[637,574,757,748]	1	hSpCas9	negative selection	8807244
143294666	143294689	7	+	27260156	T47D	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.2969005629534789	[120]	[157,184,144,204]	6	hSpCas9	negative selection	8807245
143294713	143294736	7	+	27260156	T47D	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4631491116811264	[955]	[1619,1541,1301,1684]	8	hSpCas9	negative selection	8871521
143300260	143300283	7	+	27260156	T47D	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.2603762148318358	[732]	[1200,1028,943,914]	5	hSpCas9	negative selection	8871522
143300283	143300306	7	-	27260156	T47D	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.18462984181480824	[213]	[241,295,260,334]	4	hSpCas9	negative selection	8871523
143299986	143300009	7	+	27260156	SU8686	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5899666693653789	[435]	[379,574,866,855]	8	hSpCas9	negative selection	8928494
143299967	143299990	7	-	27260156	SU8686	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.3423022089173844	[562]	[627,550,877,820]	6	hSpCas9	negative selection	8928495
143294666	143294689	7	+	27260156	SU8686	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.3686971289798995	[120]	[125,154,121,229]	6	hSpCas9	negative selection	8928496
143294713	143294736	7	+	27260156	SU8686	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.41301790835280516	[955]	[982,1226,1100,1855]	7	hSpCas9	negative selection	8992772
143300260	143300283	7	+	27260156	SU8686	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.24320409970550216	[732]	[838,742,1014,858]	4	hSpCas9	negative selection	8992773
143300283	143300306	7	-	27260156	SU8686	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.16472288778264843	[213]	[200,244,211,304]	2	hSpCas9	negative selection	8992774
143299986	143300009	7	+	27260156	SKES1	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.6243407139786427	[435]	[860,639,659,550]	9	hSpCas9	negative selection	9049745
143299967	143299990	7	-	27260156	SKES1	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.1825373046286991	[562]	[768,709,589,515]	4	hSpCas9	negative selection	9049746
143294666	143294689	7	+	27260156	SKES1	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.08873315232159684	[120]	[98,170,142,102]	2	hSpCas9	negative selection	9049747
143294713	143294736	7	+	27260156	SKES1	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.47005698478229774	[955]	[1512,1505,1043,1265]	8	hSpCas9	negative selection	9114023
143300260	143300283	7	+	27260156	SKES1	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.4437093318638726	[732]	[1045,1227,840,900]	8	hSpCas9	negative selection	9114024
143300283	143300306	7	-	27260156	SKES1	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.23014562199980493	[213]	[247,319,274,172]	5	hSpCas9	negative selection	9114025
143299986	143300009	7	+	27260156	TOV112D	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.7397936042216045	[435]	[482,737,1196,485]	9	hSpCas9	negative selection	9170996
143299967	143299990	7	-	27260156	TOV112D	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.33112371545946295	[562]	[873,663,666,635]	6	hSpCas9	negative selection	9170997
143294666	143294689	7	+	27260156	TOV112D	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.49241323655769453	[120]	[101,112,109,28]	-7	hSpCas9	negative selection	9170998
143294713	143294736	7	+	27260156	TOV112D	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.4546403724528707	[955]	[1330,1963,963,1153]	8	hSpCas9	negative selection	9235274
143300260	143300283	7	+	27260156	TOV112D	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.5554636520456399	[732]	[925,1506,917,1055]	8	hSpCas9	negative selection	9235275
143300283	143300306	7	-	27260156	TOV112D	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	-0.10301461046542504	[213]	[152,227,256,163]	-2	hSpCas9	negative selection	9235276
143299986	143300009	7	+	27260156	TC71	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4311017562289446	[435]	[564,588,798,558]	8	hSpCas9	negative selection	9292247
143299967	143299990	7	-	27260156	TC71	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	0.12319228011257038	[562]	[588,796,508,745]	3	hSpCas9	negative selection	9292248
143294666	143294689	7	+	27260156	TC71	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	0.5428153161611307	[120]	[254,219,117,161]	9	hSpCas9	negative selection	9292249
143294713	143294736	7	+	27260156	TC71	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.39669813820889455	[955]	[1286,1286,1248,1592]	8	hSpCas9	negative selection	9356525
143300260	143300283	7	+	27260156	TC71	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.19926773696008082	[732]	[880,827,932,969]	5	hSpCas9	negative selection	9356526
143300283	143300306	7	-	27260156	TC71	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.06554833658441606	[213]	[276,166,246,269]	1	hSpCas9	negative selection	9356527
143299986	143300009	7	+	27260156	TC32	viability	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.45681305476603984	[435]	[583,399,673,639]	7	hSpCas9	negative selection	9413498
143299967	143299990	7	-	27260156	TC32	viability	CGATGCAGGAGTCCGTGACTCGG	CASP2	ENSG00000106144	-0.1044440885024383	[562]	[465,318,520,720]	-2	hSpCas9	negative selection	9413499
143294666	143294689	7	+	27260156	TC32	viability	AAAGAACTGGAATTTCGCTCTGG	CASP2	ENSG00000106144	-0.032598783163201306	[120]	[74,120,122,121]	0	hSpCas9	negative selection	9413500
143294713	143294736	7	+	27260156	TC32	viability	AGTCACCCTCTTCAAGCTTTTGG	CASP2	ENSG00000106144	0.5788998979824973	[955]	[1205,961,1685,1674]	8	hSpCas9	negative selection	9477776
143300260	143300283	7	+	27260156	TC32	viability	ACCAAAAATGTTCTTCATCCAGG	CASP2	ENSG00000106144	0.4416352212425477	[732]	[973,623,1099,1141]	7	hSpCas9	negative selection	9477777
143300283	143300306	7	-	27260156	TC32	viability	AGGGCACTCACCTCCACGGCAGG	CASP2	ENSG00000106144	0.36970597371725156	[213]	[328,189,303,222]	6	hSpCas9	negative selection	9477778
143292287	143292310	7	+	27869803	HPAFII	viability after 27 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.03331679318258779	[317]	[193,151,NaN]	0	hSpCas9	negative selection	9598436
143292685	143292708	7	-	27869803	HPAFII	viability after 27 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	0.7199321065974909	[58]	[61,41,NaN]	6	hSpCas9	negative selection	9598437
143294614	143294637	7	+	27869803	HPAFII	viability after 27 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.42649440133190303	[223]	[82,220,NaN]	3	hSpCas9	negative selection	9598438
143299986	143300009	7	+	27869803	HPAFII	viability after 27 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.4784325805673531	[331]	[324,174,NaN]	4	hSpCas9	negative selection	9598439
143300191	143300214	7	+	27869803	HPAFII	viability after 27 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.5801637093017564	[352]	[211,331,NaN]	5	hSpCas9	negative selection	9598440
143303892	143303915	7	-	27869803	HPAFII	viability after 27 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.31883411397137973	[416]	[309,242,NaN]	2	hSpCas9	negative selection	9598441
143292287	143292310	7	+	27869803	HPAFII	viability after 15 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.08889120378814341	[317]	[545,249,NaN]	1	hSpCas9	negative selection	9680885
143292685	143292708	7	-	27869803	HPAFII	viability after 15 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	1.283905005800975	[58]	[146,158,NaN]	9	hSpCas9	negative selection	9680886
143294614	143294637	7	+	27869803	HPAFII	viability after 15 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.19276476645309695	[223]	[313,250,NaN]	2	hSpCas9	negative selection	9680887
143299986	143300009	7	+	27869803	HPAFII	viability after 15 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.3932940723820751	[331]	[615,376,NaN]	4	hSpCas9	negative selection	9680888
143300191	143300214	7	+	27869803	HPAFII	viability after 15 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.42436367405435793	[352]	[719,377,NaN]	5	hSpCas9	negative selection	9680889
143303892	143303915	7	-	27869803	HPAFII	viability after 15 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	-0.2259054817122229	[416]	[434,350,NaN]	-3	hSpCas9	negative selection	9680890
143292287	143292310	7	+	27869803	ASPC1	viability after 36 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	-0.17887859339812545	[757]	[352,328,71]	-2	hSpCas9	negative selection	9763334
143292685	143292708	7	-	27869803	ASPC1	viability after 36 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-1.2882192896330311	[151]	[6,52,6]	-8	hSpCas9	negative selection	9763335
143294614	143294637	7	+	27869803	ASPC1	viability after 36 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	1.0908630793763625	[352]	[273,198,301]	8	hSpCas9	negative selection	9763336
143299986	143300009	7	+	27869803	ASPC1	viability after 36 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5192137740966387	[866]	[291,950,117]	5	hSpCas9	negative selection	9763337
143300191	143300214	7	+	27869803	ASPC1	viability after 36 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.29109734747107896	[598]	[293,278,207]	3	hSpCas9	negative selection	9763338
143303892	143303915	7	-	27869803	ASPC1	viability after 36 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	1.0471988174193418	[1135]	[929,999,589]	8	hSpCas9	negative selection	9763339
143292287	143292310	7	+	27869803	PATU8988S	viability after 35 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.10138667156944964	[667]	[342,233,NaN]	1	hSpCas9	negative selection	9845783
143292685	143292708	7	-	27869803	PATU8988S	viability after 35 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.6887708991989525	[201]	[37,62,NaN]	-6	hSpCas9	negative selection	9845784
143294614	143294637	7	+	27869803	PATU8988S	viability after 35 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.02865858957314782	[374]	[180,126,NaN]	0	hSpCas9	negative selection	9845785
143299986	143300009	7	+	27869803	PATU8988S	viability after 35 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	1.1599198638567236	[639]	[773,376,NaN]	9	hSpCas9	negative selection	9845786
143300191	143300214	7	+	27869803	PATU8988S	viability after 35 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.6801080318158623	[538]	[269,425,NaN]	7	hSpCas9	negative selection	9845787
143303892	143303915	7	-	27869803	PATU8988S	viability after 35 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.2614162119216824	[955]	[468,453,NaN]	3	hSpCas9	negative selection	9845788
143292287	143292310	7	+	27869803	PATU8988S	viability after 31 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.16756305940499983	[667]	[325,264,NaN]	2	hSpCas9	negative selection	9928232
143292685	143292708	7	-	27869803	PATU8988S	viability after 31 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	-0.11382779575557533	[201]	[51,102,NaN]	-1	hSpCas9	negative selection	9928233
143294614	143294637	7	+	27869803	PATU8988S	viability after 31 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.29329606705804256	[374]	[173,194,NaN]	3	hSpCas9	negative selection	9928234
143299986	143300009	7	+	27869803	PATU8988S	viability after 31 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	1.1066189490153149	[639]	[644,427,NaN]	9	hSpCas9	negative selection	9928235
143300191	143300214	7	+	27869803	PATU8988S	viability after 31 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.2505099722352889	[538]	[245,267,NaN]	3	hSpCas9	negative selection	9928236
143303892	143303915	7	-	27869803	PATU8988S	viability after 31 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.4102351981697744	[955]	[389,654,NaN]	5	hSpCas9	negative selection	9928237
143292287	143292310	7	+	27869803	HPAFII	viability after 35 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.653190545090127	[317]	[366,124,NaN]	4	hSpCas9	negative selection	10010681
143292685	143292708	7	-	27869803	HPAFII	viability after 35 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	1.2479070134385006	[58]	[61,80,NaN]	8	hSpCas9	negative selection	10010682
143294614	143294637	7	+	27869803	HPAFII	viability after 35 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.5591548074915885	[223]	[96,245,NaN]	3	hSpCas9	negative selection	10010683
143299986	143300009	7	+	27869803	HPAFII	viability after 35 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5889153089391586	[331]	[328,166,NaN]	4	hSpCas9	negative selection	10010684
143300191	143300214	7	+	27869803	HPAFII	viability after 35 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.5695312475503767	[352]	[204,332,NaN]	3	hSpCas9	negative selection	10010685
143303892	143303915	7	-	27869803	HPAFII	viability after 35 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.9750150931715753	[416]	[215,638,NaN]	6	hSpCas9	negative selection	10010686
143292287	143292310	7	+	27869803	HPAFII	viability after 31 days	TCTTGTGTCTTAGGCCAAAGTGG	CASP2	ENSG00000106144	0.36929000175662313	[317]	[286,168,NaN]	2	hSpCas9	negative selection	10093130
143292685	143292708	7	-	27869803	HPAFII	viability after 31 days	AATTCTCACCTGTCGACAGGCGG	CASP2	ENSG00000106144	1.3474552404301867	[58]	[89,77,NaN]	8	hSpCas9	negative selection	10093131
143294614	143294637	7	+	27869803	HPAFII	viability after 31 days	TCGGCCTCGTGGCCTAGCACTGG	CASP2	ENSG00000106144	0.55527948839854	[223]	[66,312,NaN]	4	hSpCas9	negative selection	10093132
143299986	143300009	7	+	27869803	HPAFII	viability after 31 days	ATCGTGGCACTCCTCTCGCATGG	CASP2	ENSG00000106144	0.5625560876728766	[331]	[334,209,NaN]	4	hSpCas9	negative selection	10093133
143300191	143300214	7	+	27869803	HPAFII	viability after 31 days	TTCTTTCTGGCAGCTCCAAGAGG	CASP2	ENSG00000106144	0.8548998201568745	[352]	[219,508,NaN]	6	hSpCas9	negative selection	10093134
143303892	143303915	7	-	27869803	HPAFII	viability after 31 days	GCATATCATGTCTGAGCGCGTGG	CASP2	ENSG00000106144	0.5990222337997799	[416]	[286,427,NaN]	4	hSpCas9	negative selection	10093135
143288453	143288476	7	+	28162770	P31FUJ	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.2565826363245465	[51]	[72]	2	hSpCas9	negative selection	10126185
143292288	143292311	7	+	28162770	P31FUJ	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.47126490923120357	[274]	[447]	5	hSpCas9	negative selection	10126186
143288501	143288524	7	+	28162770	P31FUJ	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.3809487197314026	[214]	[328]	4	hSpCas9	negative selection	10126187
143292361	143292384	7	-	28162770	P31FUJ	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	1.2133325916094608	[217]	[593]	9	hSpCas9	negative selection	10126188
143291648	143291671	7	+	28162770	P31FUJ	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.756444739288747	[403]	[801]	8	hSpCas9	negative selection	10126189
143292308	143292331	7	+	28162770	P31FUJ	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	1.2434223567834475	[527]	[1468]	9	hSpCas9	negative selection	10126190
143291669	143291692	7	+	28162770	P31FUJ	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.8055441072351042	[296]	[609]	8	hSpCas9	negative selection	10126191
143291633	143291656	7	+	28162770	P31FUJ	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.9113688992722551	[470]	[1040]	9	hSpCas9	negative selection	10126192
143288465	143288488	7	-	28162770	P31FUJ	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.3506889090901094	[326]	[489]	4	hSpCas9	negative selection	10126193
143288511	143288534	7	-	28162770	P31FUJ	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.3521602963067776	[64]	[194]	9	hSpCas9	negative selection	10126194
143288453	143288476	7	+	28162770	TF1	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10295551
143292288	143292311	7	+	28162770	TF1	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	NaN	[NaN]	[404]	1	hSpCas9	negative selection	10295552
143288501	143288524	7	+	28162770	TF1	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10295553
143292361	143292384	7	-	28162770	TF1	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10295554
143291648	143291671	7	+	28162770	TF1	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	NaN	[NaN]	[647]	1	hSpCas9	negative selection	10295555
143292308	143292331	7	+	28162770	TF1	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	NaN	[NaN]	[733]	1	hSpCas9	negative selection	10295556
143291669	143291692	7	+	28162770	TF1	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	NaN	[NaN]	[467]	1	hSpCas9	negative selection	10295557
143291633	143291656	7	+	28162770	TF1	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	NaN	[NaN]	[898]	1	hSpCas9	negative selection	10295558
143288465	143288488	7	-	28162770	TF1	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10295559
143288511	143288534	7	-	28162770	TF1	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10295560
143288453	143288476	7	+	28162770	SKM1	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.9435330483409714	[9]	[33]	8	hSpCas9	negative selection	10464917
143292288	143292311	7	+	28162770	SKM1	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.5303000459088757	[46]	[119]	5	hSpCas9	negative selection	10464918
143288501	143288524	7	+	28162770	SKM1	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.06597168424388322	[86]	[160]	0	hSpCas9	negative selection	10464919
143292361	143292384	7	-	28162770	SKM1	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5739269783091336	[75]	[199]	5	hSpCas9	negative selection	10464920
143291648	143291671	7	+	28162770	SKM1	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	-0.17926286602164843	[154]	[241]	-1	hSpCas9	negative selection	10464921
143292308	143292331	7	+	28162770	SKM1	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.13440903343031185	[167]	[325]	1	hSpCas9	negative selection	10464922
143291669	143291692	7	+	28162770	SKM1	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.0080733005356821	[62]	[223]	8	hSpCas9	negative selection	10464923
143291633	143291656	7	+	28162770	SKM1	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.564180938584653	[100]	[263]	5	hSpCas9	negative selection	10464924
143288465	143288488	7	-	28162770	SKM1	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.508387975613553	[67]	[170]	5	hSpCas9	negative selection	10464925
143288511	143288534	7	-	28162770	SKM1	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.23689199103156322	[11]	[24]	2	hSpCas9	negative selection	10464926
143288453	143288476	7	+	28162770	SKM1	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.9435330483409714	[9]	[33]	8	hSpCas9	negative selection	10634283
143292288	143292311	7	+	28162770	SKM1	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.5303000459088757	[46]	[119]	5	hSpCas9	negative selection	10634284
143288501	143288524	7	+	28162770	SKM1	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.06597168424388322	[86]	[160]	0	hSpCas9	negative selection	10634285
143292361	143292384	7	-	28162770	SKM1	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5739269783091336	[75]	[199]	5	hSpCas9	negative selection	10634286
143291648	143291671	7	+	28162770	SKM1	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	-0.17926286602164843	[154]	[241]	-1	hSpCas9	negative selection	10634287
143292308	143292331	7	+	28162770	SKM1	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.13440903343031185	[167]	[325]	1	hSpCas9	negative selection	10634288
143291669	143291692	7	+	28162770	SKM1	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.0080733005356821	[62]	[223]	8	hSpCas9	negative selection	10634289
143291633	143291656	7	+	28162770	SKM1	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.564180938584653	[100]	[263]	5	hSpCas9	negative selection	10634290
143288465	143288488	7	-	28162770	SKM1	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.508387975613553	[67]	[170]	5	hSpCas9	negative selection	10634291
143288511	143288534	7	-	28162770	SKM1	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.23689199103156322	[11]	[24]	2	hSpCas9	negative selection	10634292
143288453	143288476	7	+	28162770	PL21	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	1.515012951842732	[40]	[50]	9	hSpCas9	negative selection	10803649
143292288	143292311	7	+	28162770	PL21	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.6375449267966184	[191]	[129]	5	hSpCas9	negative selection	10803650
143288501	143288524	7	+	28162770	PL21	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.38552887642891687	[298]	[169]	3	hSpCas9	negative selection	10803651
143292361	143292384	7	-	28162770	PL21	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.740707995852023	[241]	[175]	6	hSpCas9	negative selection	10803652
143291648	143291671	7	+	28162770	PL21	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.058478465265729085	[555]	[251]	0	hSpCas9	negative selection	10803653
143292308	143292331	7	+	28162770	PL21	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.9802028448791842	[586]	[503]	7	hSpCas9	negative selection	10803654
143291669	143291692	7	+	28162770	PL21	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.3719059627558003	[173]	[195]	9	hSpCas9	negative selection	10803655
143291633	143291656	7	+	28162770	PL21	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	1.1450682319956442	[266]	[256]	8	hSpCas9	negative selection	10803656
143288465	143288488	7	-	28162770	PL21	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	-0.8807803808942474	[219]	[51]	-6	hSpCas9	negative selection	10803657
143288511	143288534	7	-	28162770	PL21	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	-0.5692474573692634	[74]	[21]	-4	hSpCas9	negative selection	10803658
143288453	143288476	7	+	28162770	P31FUJ	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.2565826363245465	[51]	[72]	2	hSpCas9	negative selection	10973015
143292288	143292311	7	+	28162770	P31FUJ	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.47126490923120357	[274]	[447]	5	hSpCas9	negative selection	10973016
143288501	143288524	7	+	28162770	P31FUJ	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.3809487197314026	[214]	[328]	4	hSpCas9	negative selection	10973017
143292361	143292384	7	-	28162770	P31FUJ	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	1.2133325916094608	[217]	[593]	9	hSpCas9	negative selection	10973018
143291648	143291671	7	+	28162770	P31FUJ	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.756444739288747	[403]	[801]	8	hSpCas9	negative selection	10973019
143292308	143292331	7	+	28162770	P31FUJ	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	1.2434223567834475	[527]	[1468]	9	hSpCas9	negative selection	10973020
143291669	143291692	7	+	28162770	P31FUJ	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.8055441072351042	[296]	[609]	8	hSpCas9	negative selection	10973021
143291633	143291656	7	+	28162770	P31FUJ	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.9113688992722551	[470]	[1040]	9	hSpCas9	negative selection	10973022
143288465	143288488	7	-	28162770	P31FUJ	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.3506889090901094	[326]	[489]	4	hSpCas9	negative selection	10973023
143288511	143288534	7	-	28162770	P31FUJ	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.3521602963067776	[64]	[194]	9	hSpCas9	negative selection	10973024
143288453	143288476	7	+	28162770	OCIAML5	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.294774817465274	[13]	[30]	2	hSpCas9	negative selection	11142381
143292288	143292311	7	+	28162770	OCIAML5	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.7091612810647986	[142]	[421]	6	hSpCas9	negative selection	11142382
143288501	143288524	7	+	28162770	OCIAML5	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	-0.16266665994984658	[110]	[178]	-1	hSpCas9	negative selection	11142383
143292361	143292384	7	-	28162770	OCIAML5	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.7402754602227568	[129]	[391]	6	hSpCas9	negative selection	11142384
143291648	143291671	7	+	28162770	OCIAML5	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.7030254002750216	[243]	[716]	6	hSpCas9	negative selection	11142385
143292308	143292331	7	+	28162770	OCIAML5	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	1.3452348695096206	[231]	[1063]	9	hSpCas9	negative selection	11142386
143291669	143291692	7	+	28162770	OCIAML5	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.3092453002736073	[111]	[500]	9	hSpCas9	negative selection	11142387
143291633	143291656	7	+	28162770	OCIAML5	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.6180122919728088	[269]	[747]	5	hSpCas9	negative selection	11142388
143288465	143288488	7	-	28162770	OCIAML5	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.038110151183251895	[190]	[353]	0	hSpCas9	negative selection	11142389
143288511	143288534	7	-	28162770	OCIAML5	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.6784481458347826	[71]	[207]	6	hSpCas9	negative selection	11142390
143288453	143288476	7	+	28162770	EOL1	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.8853771742898567	[111]	[108]	7	hSpCas9	negative selection	11311747
143292288	143292311	7	+	28162770	EOL1	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	-0.689798535931716	[247]	[80]	-5	hSpCas9	negative selection	11311748
143288501	143288524	7	+	28162770	EOL1	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.31002081330723996	[492]	[321]	3	hSpCas9	negative selection	11311749
143292361	143292384	7	-	28162770	EOL1	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5320065884127466	[402]	[306]	5	hSpCas9	negative selection	11311750
143291648	143291671	7	+	28162770	EOL1	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.45483317967137626	[967]	[698]	4	hSpCas9	negative selection	11311751
143292308	143292331	7	+	28162770	EOL1	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.16727462916647995	[1096]	[648]	1	hSpCas9	negative selection	11311752
143291669	143291692	7	+	28162770	EOL1	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.11029329049524594	[261]	[148]	1	hSpCas9	negative selection	11311753
143291633	143291656	7	+	28162770	EOL1	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.9288097984246944	[337]	[338]	7	hSpCas9	negative selection	11311754
143288465	143288488	7	-	28162770	EOL1	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	-0.124546777957635	[268]	[129]	-1	hSpCas9	negative selection	11311755
143288511	143288534	7	-	28162770	EOL1	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.9985483530143116	[56]	[59]	8	hSpCas9	negative selection	11311756
143288453	143288476	7	+	28162770	MOLM13	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	0.8060581174391519	[105]	[133]	6	hSpCas9	negative selection	11481113
143292288	143292311	7	+	28162770	MOLM13	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.6755807535345979	[309]	[357]	5	hSpCas9	negative selection	11481114
143288501	143288524	7	+	28162770	MOLM13	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.39026848442210516	[419]	[397]	3	hSpCas9	negative selection	11481115
143292361	143292384	7	-	28162770	MOLM13	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.4341405901900384	[345]	[337]	3	hSpCas9	negative selection	11481116
143291648	143291671	7	+	28162770	MOLM13	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	1.1505779147275863	[779]	[1251]	8	hSpCas9	negative selection	11481117
143292308	143292331	7	+	28162770	MOLM13	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.9826382677952823	[820]	[1172]	7	hSpCas9	negative selection	11481118
143291669	143291692	7	+	28162770	MOLM13	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.11399217707963905	[307]	[240]	0	hSpCas9	negative selection	11481119
143291633	143291656	7	+	28162770	MOLM13	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.8346717122162016	[455]	[587]	6	hSpCas9	negative selection	11481120
143288465	143288488	7	-	28162770	MOLM13	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	-0.7197376216311925	[286]	[125]	-4	hSpCas9	negative selection	11481121
143288511	143288534	7	-	28162770	MOLM13	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	-2.854038713342783	[89]	[8]	-8	hSpCas9	negative selection	11481122
143288453	143288476	7	+	28162770	HEL	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	-0.04793310989191424	[91]	[56]	0	hSpCas9	negative selection	11650479
143292288	143292311	7	+	28162770	HEL	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	-0.33588751720707605	[200]	[101]	-2	hSpCas9	negative selection	11650480
143288501	143288524	7	+	28162770	HEL	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	1.090197808971578	[340]	[464]	8	hSpCas9	negative selection	11650481
143292361	143292384	7	-	28162770	HEL	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	1.381734961393934	[283]	[473]	9	hSpCas9	negative selection	11650482
143291648	143291671	7	+	28162770	HEL	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.934404526283271	[606]	[742]	7	hSpCas9	negative selection	11650483
143292308	143292331	7	+	28162770	HEL	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.32465166686816893	[843]	[676]	2	hSpCas9	negative selection	11650484
143291669	143291692	7	+	28162770	HEL	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.9611003118675269	[242]	[302]	8	hSpCas9	negative selection	11650485
143291633	143291656	7	+	28162770	HEL	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.45106103202975634	[425]	[372]	4	hSpCas9	negative selection	11650486
143288465	143288488	7	-	28162770	HEL	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.8505437171137586	[212]	[245]	7	hSpCas9	negative selection	11650487
143288511	143288534	7	-	28162770	HEL	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.208336007854582	[49]	[73]	9	hSpCas9	negative selection	11650488
143288453	143288476	7	+	28162770	MV411	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	1.534318698570937	[49]	[121]	9	hSpCas9	negative selection	11819845
143292288	143292311	7	+	28162770	MV411	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.2549320873296995	[191]	[192]	2	hSpCas9	negative selection	11819846
143288501	143288524	7	+	28162770	MV411	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	-0.4121380107124728	[247]	[156]	-3	hSpCas9	negative selection	11819847
143292361	143292384	7	-	28162770	MV411	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5071592225757335	[217]	[260]	4	hSpCas9	negative selection	11819848
143291648	143291671	7	+	28162770	MV411	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.8090102312283509	[455]	[672]	7	hSpCas9	negative selection	11819849
143292308	143292331	7	+	28162770	MV411	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.5768993183555451	[572]	[719]	5	hSpCas9	negative selection	11819850
143291669	143291692	7	+	28162770	MV411	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	1.3739122961916903	[190]	[416]	9	hSpCas9	negative selection	11819851
143291633	143291656	7	+	28162770	MV411	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.4202741476449908	[329]	[371]	4	hSpCas9	negative selection	11819852
143288465	143288488	7	-	28162770	MV411	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.3475490355729794	[166]	[178]	3	hSpCas9	negative selection	11819853
143288511	143288534	7	-	28162770	MV411	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.768269714084216	[68]	[98]	7	hSpCas9	negative selection	11819854
143288453	143288476	7	+	28162770	MONOMAC1	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	-0.13144850543197673	[42]	[44]	-1	hSpCas9	negative selection	11989211
143292288	143292311	7	+	28162770	MONOMAC1	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.946157788768237	[114]	[253]	8	hSpCas9	negative selection	11989212
143288501	143288524	7	+	28162770	MONOMAC1	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.8492568052143814	[137]	[284]	7	hSpCas9	negative selection	11989213
143292361	143292384	7	-	28162770	MONOMAC1	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.5961321687547392	[145]	[252]	6	hSpCas9	negative selection	11989214
143291648	143291671	7	+	28162770	MONOMAC1	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.35475878972640307	[351]	[515]	3	hSpCas9	negative selection	11989215
143292308	143292331	7	+	28162770	MONOMAC1	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.9167053189896344	[383]	[830]	8	hSpCas9	negative selection	11989216
143291669	143291692	7	+	28162770	MONOMAC1	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.6545713130477753	[132]	[239]	6	hSpCas9	negative selection	11989217
143291633	143291656	7	+	28162770	MONOMAC1	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	0.10647662812931036	[204]	[252]	1	hSpCas9	negative selection	11989218
143288465	143288488	7	-	28162770	MONOMAC1	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	2.5352166197573314	[137]	[916]	9	hSpCas9	negative selection	11989219
143288511	143288534	7	-	28162770	MONOMAC1	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.6856062023022873	[31]	[58]	6	hSpCas9	negative selection	11989220
143288453	143288476	7	+	28162770	OCIAML2	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	-0.03453071043548772	[16]	[91]	0	hSpCas9	negative selection	12158577
143292288	143292311	7	+	28162770	OCIAML2	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	0.30259931291081654	[54]	[375]	3	hSpCas9	negative selection	12158578
143288501	143288524	7	+	28162770	OCIAML2	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.3938255040459608	[45]	[334]	4	hSpCas9	negative selection	12158579
143292361	143292384	7	-	28162770	OCIAML2	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.23744321780135824	[57]	[378]	2	hSpCas9	negative selection	12158580
143291648	143291671	7	+	28162770	OCIAML2	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	0.1807339012015048	[91]	[577]	1	hSpCas9	negative selection	12158581
143292308	143292331	7	+	28162770	OCIAML2	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.20940093290853334	[114]	[736]	2	hSpCas9	negative selection	12158582
143291669	143291692	7	+	28162770	OCIAML2	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.7399371606974972	[34]	[323]	7	hSpCas9	negative selection	12158583
143291633	143291656	7	+	28162770	OCIAML2	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	1.2377150909842771	[55]	[731]	9	hSpCas9	negative selection	12158584
143288465	143288488	7	-	28162770	OCIAML2	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	0.8999330448960777	[34]	[361]	8	hSpCas9	negative selection	12158585
143288511	143288534	7	-	28162770	OCIAML2	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	0.8248260582840102	[10]	[107]	7	hSpCas9	negative selection	12158586
143288453	143288476	7	+	28162770	OCIAML3	viability	GAAATGGCGGCGCCGAGCGCGGG	CASP2	ENSG00000106144	2.505528033226751	[13]	[239]	9	hSpCas9	negative selection	12327943
143292288	143292311	7	+	28162770	OCIAML3	viability	CTTGTGTCTTAGGCCAAAGTGGG	CASP2	ENSG00000106144	-0.03652587602511404	[52]	[155]	0	hSpCas9	negative selection	12327944
143288501	143288524	7	+	28162770	OCIAML3	viability	GAGCTGATGGCCGCTGACAGGGG	CASP2	ENSG00000106144	0.9264661339452793	[60]	[349]	7	hSpCas9	negative selection	12327945
143292361	143292384	7	-	28162770	OCIAML3	viability	ACAGAAGGCATCAAAAGCTTGGG	CASP2	ENSG00000106144	0.4100391927385387	[88]	[356]	4	hSpCas9	negative selection	12327946
143291648	143291671	7	+	28162770	OCIAML3	viability	GGAGAAGGACATCATCACCTTGG	CASP2	ENSG00000106144	-0.0025170966055092503	[146]	[442]	0	hSpCas9	negative selection	12327947
143292308	143292331	7	+	28162770	OCIAML3	viability	GGGCAGTTTCAGCCAGAATGTGG	CASP2	ENSG00000106144	0.011039106440325241	[213]	[650]	0	hSpCas9	negative selection	12327948
143291669	143291692	7	+	28162770	OCIAML3	viability	GGAAATGAGGGAGCTCATCCAGG	CASP2	ENSG00000106144	0.9516419363721671	[61]	[361]	8	hSpCas9	negative selection	12327949
143291633	143291656	7	+	28162770	OCIAML3	viability	GTTAGAACATCTTCTGGAGAAGG	CASP2	ENSG00000106144	-0.4259697484261162	[84]	[190]	-3	hSpCas9	negative selection	12327950
143288465	143288488	7	-	28162770	OCIAML3	viability	GTGGACCAAGACCCCGCGCTCGG	CASP2	ENSG00000106144	-0.33661979763151123	[63]	[152]	-3	hSpCas9	negative selection	12327951
143288511	143288534	7	-	28162770	OCIAML3	viability	TTACCTGCGTCCCCTGTCAGCGG	CASP2	ENSG00000106144	1.9343713320306255	[12]	[149]	9	hSpCas9	negative selection	12327952