Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6792
  • Symbol: CDKL5
  • Description: cyclin dependent kinase like 5
DataSource: http://genomecrispr.dkfz.de/#!/results/CDKL5

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
18587997 18588020 X + 26472758 Jiyoye viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.33348983337285587 [240] [228] 2 hSpCas9 negative selection 28961
18603957 18603980 X + 26472758 Jiyoye viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.35406404504631106 [248] [239] 2 hSpCas9 negative selection 28962
18604371 18604394 X + 26472758 Jiyoye viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 1.441122713429211 [20] [42] 8 hSpCas9 negative selection 28963
18604804 18604827 X + 26472758 Jiyoye viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.856389996102805 [218] [298] 6 hSpCas9 negative selection 28964
18609549 18609572 X + 26472758 Jiyoye viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 -0.3297902126603329 [219] [131] -2 hSpCas9 negative selection 28965
18613154 18613177 X - 26472758 Jiyoye viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.278158323643767 [338] [309] 2 hSpCas9 negative selection 28966
18625192 18625215 X + 26472758 Jiyoye viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.9921378822270296 [105] [158] 6 hSpCas9 negative selection 28967
18628526 18628549 X + 26472758 Jiyoye viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 0.6872833006986085 [27] [33] 5 hSpCas9 negative selection 28968
18564473 18564496 X + 26472758 Jiyoye viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.160297991879772 [514] [433] 1 hSpCas9 negative selection 28969
18584317 18584340 X - 26472758 Jiyoye viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 -0.011537775916368537 [130] [97] 0 hSpCas9 negative selection 28970
18587997 18588020 X + 26472758 KBM7 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.7295210684238342 [848,523] [640,420] 7 hSpCas9 negative selection 220079
18603957 18603980 X + 26472758 KBM7 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.2615182606088058 [956,932] [343,396] -3 hSpCas9 negative selection 220080
18604371 18604394 X + 26472758 KBM7 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.3861834041583043 [223,259] [205,100] 4 hSpCas9 negative selection 220081
18604804 18604827 X + 26472758 KBM7 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 1.2569434174610545 [1052,862] [1281,881] 9 hSpCas9 negative selection 220082
18609549 18609572 X + 26472758 KBM7 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.7325231727284979 [441,284] [267,288] 7 hSpCas9 negative selection 220083
18613154 18613177 X - 26472758 KBM7 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.1818052383916373 [1094,832] [622,407] 1 hSpCas9 negative selection 220084
18625192 18625215 X + 26472758 KBM7 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.17984307078854606 [658,663] [265,432] 1 hSpCas9 negative selection 220085
18628526 18628549 X + 26472758 KBM7 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 0.43060591472081544 [178,89] [39,120] 4 hSpCas9 negative selection 220086
18564473 18564496 X + 26472758 KBM7 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.24475487655257133 [2122,2094] [1200,1160] 2 hSpCas9 negative selection 220087
18584317 18584340 X - 26472758 KBM7 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 -0.16939755070713391 [883,832] [338,377] -2 hSpCas9 negative selection 220088
18587997 18588020 X + 26472758 Raji viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.6828857068456893 [305] [113] 6 hSpCas9 negative selection 411197
18603957 18603980 X + 26472758 Raji viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.024840756883489412 [490] [111] 0 hSpCas9 negative selection 411198
18604371 18604394 X + 26472758 Raji viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.3231122264290365 [61] [17] 3 hSpCas9 negative selection 411199
18604804 18604827 X + 26472758 Raji viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.3034112527106476 [425] [121] 3 hSpCas9 negative selection 411200
18609549 18609572 X + 26472758 Raji viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.6378982520723793 [179] [64] 6 hSpCas9 negative selection 411201
18613154 18613177 X - 26472758 Raji viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.9624048910615178 [386] [174] 8 hSpCas9 negative selection 411202
18625192 18625215 X + 26472758 Raji viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 -0.3038920451090452 [382] [71] -3 hSpCas9 negative selection 411203
18628526 18628549 X + 26472758 Raji viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.3374013072992965 [97] [17] -3 hSpCas9 negative selection 411204
18564473 18564496 X + 26472758 Raji viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.38249077350796856 [1070] [323] 3 hSpCas9 negative selection 411205
18584317 18584340 X - 26472758 Raji viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5369571278103237 [394] [132] 5 hSpCas9 negative selection 411206
18587997 18588020 X + 26472758 K562 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 -0.03471620545609966 [846] [697] 0 hSpCas9 negative selection 602315
18603957 18603980 X + 26472758 K562 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.3276578880338672 [824] [873] 2 hSpCas9 negative selection 602316
18604371 18604394 X + 26472758 K562 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.09347682959170722 [150] [135] 0 hSpCas9 negative selection 602317
18604804 18604827 X + 26472758 K562 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.9574204189112883 [861] [1412] 7 hSpCas9 negative selection 602318
18609549 18609572 X + 26472758 K562 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.36315627424996966 [407] [442] 3 hSpCas9 negative selection 602319
18613154 18613177 X - 26472758 K562 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.3375281320579282 [929] [991] 2 hSpCas9 negative selection 602320
18625192 18625215 X + 26472758 K562 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.7963856579535116 [456] [669] 6 hSpCas9 negative selection 602321
18628526 18628549 X + 26472758 K562 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 1.3318815689167862 [87] [186] 9 hSpCas9 negative selection 602322
18564473 18564496 X + 26472758 K562 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 1.0993226254674773 [1666] [3014] 8 hSpCas9 negative selection 602323
18584317 18584340 X - 26472758 K562 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.6297645420084854 [809] [1057] 5 hSpCas9 negative selection 602324
18575433 18575456 X + 26627737 DLD1 viability GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.721355009952494 [73] [84,23,111] 9 hSpCas9 negative selection 845262
18584305 18584328 X + 26627737 DLD1 viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.4427864609412886 [479] [228,138,235] 4 hSpCas9 negative selection 845263
18588131 18588154 X - 26627737 DLD1 viability AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.18667022288691815 [199] [46,102,21] -2 hSpCas9 negative selection 845264
18595362 18595385 X - 26627737 DLD1 viability TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.7730472952950502 [138] [88,40,88] 7 hSpCas9 negative selection 845265
18598480 18598503 X - 26627737 DLD1 viability TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.3701187982288956 [317] [141,68,165] 4 hSpCas9 negative selection 845266
18604634 18604657 X + 26627737 DLD1 viability ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.6494918541268234 [455] [138,49,82] -6 hSpCas9 negative selection 845267
18575433 18575456 X + 26627737 GBM cells viability after 5 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.6659367029080718 [56] [48,47] 8 hSpCas9 negative selection 927577
18584305 18584328 X + 26627737 GBM cells viability after 5 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.15267046713146862 [233] [108,169] 2 hSpCas9 negative selection 927578
18588131 18588154 X - 26627737 GBM cells viability after 5 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.19811057950917932 [122] [67,46] -3 hSpCas9 negative selection 927579
18595362 18595385 X - 26627737 GBM cells viability after 5 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.06883887632799773 [175] [75,121] 1 hSpCas9 negative selection 927580
18598480 18598503 X - 26627737 GBM cells viability after 5 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.29533569599718235 [116] [105,47] 4 hSpCas9 negative selection 927581
18604634 18604657 X + 26627737 GBM cells viability after 5 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.16038330879808638 [148] [71,70] -2 hSpCas9 negative selection 927582
18575433 18575456 X + 26627737 GBM cells viability after 13 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -0.37780808162746027 [56] [41,8] -4 hSpCas9 negative selection 1009892
18584305 18584328 X + 26627737 GBM cells viability after 13 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.4924098256538674 [233] [230,135] 6 hSpCas9 negative selection 1009893
18588131 18588154 X - 26627737 GBM cells viability after 13 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.10655730718168721 [122] [104,26] -1 hSpCas9 negative selection 1009894
18595362 18595385 X - 26627737 GBM cells viability after 13 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 -0.00012184228201239655 [175] [100,90] 0 hSpCas9 negative selection 1009895
18598480 18598503 X - 26627737 GBM cells viability after 13 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.3232863956966937 [116] [106,56] 4 hSpCas9 negative selection 1009896
18604634 18604657 X + 26627737 GBM cells viability after 13 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.7940335766284764 [148] [55,38] -7 hSpCas9 negative selection 1009897
18575433 18575456 X + 26627737 GBM cells viability after 21 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.29358244874173267 [56] [38,36] 3 hSpCas9 negative selection 1092207
18584305 18584328 X + 26627737 GBM cells viability after 21 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.40018086692063737 [233] [184,151] 4 hSpCas9 negative selection 1092208
18588131 18588154 X - 26627737 GBM cells viability after 21 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -1.029592587017407 [122] [38,26] -7 hSpCas9 negative selection 1092209
18595362 18595385 X - 26627737 GBM cells viability after 21 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.17078281098382325 [175] [127,88] 1 hSpCas9 negative selection 1092210
18598480 18598503 X - 26627737 GBM cells viability after 21 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.17711944717624084 [116] [74,68] 2 hSpCas9 negative selection 1092211
18604634 18604657 X + 26627737 GBM cells viability after 21 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.47571257050711846 [148] [64,51] -4 hSpCas9 negative selection 1092212
18575433 18575456 X + 26627737 RPE1 viability after 9 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -0.14676978807312424 [256] [66,79] -1 hSpCas9 negative selection 1174522
18584305 18584328 X + 26627737 RPE1 viability after 9 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 -0.31370535918471326 [835] [186,240] -2 hSpCas9 negative selection 1174523
18588131 18588154 X - 26627737 RPE1 viability after 9 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.752214527530514 [116] [132,110] 8 hSpCas9 negative selection 1174524
18595362 18595385 X - 26627737 RPE1 viability after 9 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.6607570653817394 [373] [257,514] 8 hSpCas9 negative selection 1174525
18598480 18598503 X - 26627737 RPE1 viability after 9 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -0.6662859483306294 [936] [107,283] -5 hSpCas9 negative selection 1174526
18604634 18604657 X + 26627737 RPE1 viability after 9 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.36189965319484874 [694] [152,442] 2 hSpCas9 negative selection 1174527
18575433 18575456 X + 26627737 RPE1 viability after 12 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.2675114266345995 [256] [35,132] 1 hSpCas9 negative selection 1256837
18584305 18584328 X + 26627737 RPE1 viability after 12 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.02561417599289069 [835] [283,169] 0 hSpCas9 negative selection 1256838
18588131 18588154 X - 26627737 RPE1 viability after 12 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 2.090297007691316 [116] [145,120] 9 hSpCas9 negative selection 1256839
18595362 18595385 X - 26627737 RPE1 viability after 12 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.7832493937268334 [373] [272,422] 8 hSpCas9 negative selection 1256840
18598480 18598503 X - 26627737 RPE1 viability after 12 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -0.9601000188809039 [936] [57,204] -6 hSpCas9 negative selection 1256841
18604634 18604657 X + 26627737 RPE1 viability after 12 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.39624791707898155 [694] [168,326] 2 hSpCas9 negative selection 1256842
18575433 18575456 X + 26627737 RPE1 viability after 15 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -0.21709947089088666 [256] [31,91] -1 hSpCas9 negative selection 1339152
18584305 18584328 X + 26627737 RPE1 viability after 15 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.05368972609337082 [835] [219,269] 0 hSpCas9 negative selection 1339153
18588131 18588154 X - 26627737 RPE1 viability after 15 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 2.0905882291560856 [116] [170,111] 8 hSpCas9 negative selection 1339154
18595362 18595385 X - 26627737 RPE1 viability after 15 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.754918080130539 [373] [324,387] 8 hSpCas9 negative selection 1339155
18598480 18598503 X - 26627737 RPE1 viability after 15 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -0.9239541346535747 [936] [43,231] -5 hSpCas9 negative selection 1339156
18604634 18604657 X + 26627737 RPE1 viability after 15 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.4634381970403463 [694] [322,220] 3 hSpCas9 negative selection 1339157
18575433 18575456 X + 26627737 RPE1 viability after 18 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -0.37967459872778564 [256] [3,105] -2 hSpCas9 negative selection 1421467
18584305 18584328 X + 26627737 RPE1 viability after 18 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.09522683499681907 [835] [211,271] 0 hSpCas9 negative selection 1421468
18588131 18588154 X - 26627737 RPE1 viability after 18 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 2.412231317851417 [116] [140,196] 9 hSpCas9 negative selection 1421469
18595362 18595385 X - 26627737 RPE1 viability after 18 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.5493599952174615 [373] [219,375] 7 hSpCas9 negative selection 1421470
18598480 18598503 X - 26627737 RPE1 viability after 18 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -0.4879927677925243 [936] [86,279] -3 hSpCas9 negative selection 1421471
18604634 18604657 X + 26627737 RPE1 viability after 18 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.12584234751843448 [694] [179,230] 0 hSpCas9 negative selection 1421472
18575433 18575456 X + 26627737 HeLa viability after 8 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 2.0105682836725967 [46] [217,34,27] 9 hSpCas9 negative selection 1503782
18584305 18584328 X + 26627737 HeLa viability after 8 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.43927983732331377 [405] [448,257,69] 4 hSpCas9 negative selection 1503783
18588131 18588154 X - 26627737 HeLa viability after 8 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.305711054381195 [98] [52,122,129] 8 hSpCas9 negative selection 1503784
18595362 18595385 X - 26627737 HeLa viability after 8 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.6252981986863897 [166] [123,133,82] 5 hSpCas9 negative selection 1503785
18598480 18598503 X - 26627737 HeLa viability after 8 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -0.11117053231135743 [177] [104,38,77] -1 hSpCas9 negative selection 1503786
18604634 18604657 X + 26627737 HeLa viability after 8 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.042527966364302006 [212] [102,22,142] 0 hSpCas9 negative selection 1503787
18575433 18575456 X + 26627737 HeLa viability after 12 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 2.3672175717156323 [46] [69,97,131] 9 hSpCas9 negative selection 1586097
18584305 18584328 X + 26627737 HeLa viability after 12 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.40386195765346344 [405] [389,229,49] 3 hSpCas9 negative selection 1586098
18588131 18588154 X - 26627737 HeLa viability after 12 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.14575378603911826 [98] [13,62,55] 1 hSpCas9 negative selection 1586099
18595362 18595385 X - 26627737 HeLa viability after 12 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.38914022881522636 [166] [122,62,88] 3 hSpCas9 negative selection 1586100
18598480 18598503 X - 26627737 HeLa viability after 12 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.006517048020439287 [177] [27,29,166] 0 hSpCas9 negative selection 1586101
18604634 18604657 X + 26627737 HeLa viability after 12 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.002888702979623403 [212] [113,100,48] 0 hSpCas9 negative selection 1586102
18575433 18575456 X + 26627737 HeLa viability after 15 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.5654121334383488 [46] [122,25,16] 8 hSpCas9 negative selection 1668412
18584305 18584328 X + 26627737 HeLa viability after 15 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.011259348171920196 [405] [165,151,182] 0 hSpCas9 negative selection 1668413
18588131 18588154 X - 26627737 HeLa viability after 15 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.9115041272767526 [98] [129,65,26] 7 hSpCas9 negative selection 1668414
18595362 18595385 X - 26627737 HeLa viability after 15 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.1750836917511709 [166] [68,64,97] 1 hSpCas9 negative selection 1668415
18598480 18598503 X - 26627737 HeLa viability after 15 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.01315066220422545 [177] [30,126,60] 0 hSpCas9 negative selection 1668416
18604634 18604657 X + 26627737 HeLa viability after 15 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.1695558231430605 [212] [71,73,150] 1 hSpCas9 negative selection 1668417
18575433 18575456 X + 26627737 HeLa viability after 18 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.6889513445250088 [46] [91,21,16] 9 hSpCas9 negative selection 1750727
18584305 18584328 X + 26627737 HeLa viability after 18 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.09738106550784292 [405] [127,129,182] 0 hSpCas9 negative selection 1750728
18588131 18588154 X - 26627737 HeLa viability after 18 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.9159433512285922 [98] [88,52,26] 7 hSpCas9 negative selection 1750729
18595362 18595385 X - 26627737 HeLa viability after 18 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.14230478155412807 [166] [41,54,97] 1 hSpCas9 negative selection 1750730
18598480 18598503 X - 26627737 HeLa viability after 18 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.013886923204566859 [177] [20,104,60] 0 hSpCas9 negative selection 1750731
18604634 18604657 X + 26627737 HeLa viability after 18 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.204649760382157 [212] [53,59,150] 1 hSpCas9 negative selection 1750732
18575433 18575456 X + 26627737 HCT116 viability after 6 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -1.0127861549558437 [163] [15,10] -5 hSpCas9 negative selection 1833042
18584305 18584328 X + 26627737 HCT116 viability after 6 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.6165395773891758 [678] [211,136] 3 hSpCas9 negative selection 1833043
18588131 18588154 X - 26627737 HCT116 viability after 6 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -1.2431577997401053 [465] [77,4] -6 hSpCas9 negative selection 1833044
18595362 18595385 X - 26627737 HCT116 viability after 6 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.052214967040976 [266] [97,80] 6 hSpCas9 negative selection 1833045
18598480 18598503 X - 26627737 HCT116 viability after 6 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 -1.4456238815698654 [510] [4,42] -7 hSpCas9 negative selection 1833046
18604634 18604657 X + 26627737 HCT116 viability after 6 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.8815198337157821 [648] [118,225] 5 hSpCas9 negative selection 1833047
18575433 18575456 X + 26627737 HCT116 viability after 8 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.927604896737577 [41] [45,33,51] 8 hSpCas9 negative selection 1915357
18584305 18584328 X + 26627737 HCT116 viability after 8 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 -0.12822810135626345 [434] [251,226,179] -1 hSpCas9 negative selection 1915358
18588131 18588154 X - 26627737 HCT116 viability after 8 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.2899307772398265 [118] [75,48,114] 3 hSpCas9 negative selection 1915359
18595362 18595385 X - 26627737 HCT116 viability after 8 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.7181139779280028 [54] [93,102,101] 9 hSpCas9 negative selection 1915360
18598480 18598503 X - 26627737 HCT116 viability after 8 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 1.227958532901769 [121] [134,179,156] 8 hSpCas9 negative selection 1915361
18604634 18604657 X + 26627737 HCT116 viability after 8 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.32712147787958146 [145] [94,38,58] -4 hSpCas9 negative selection 1915362
18575433 18575456 X + 26627737 HCT116 viability after 9 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.4002554903623237 [163] [47,168] 8 hSpCas9 negative selection 1997672
18584305 18584328 X + 26627737 HCT116 viability after 9 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 -0.14893240633047042 [678] [86,223] -1 hSpCas9 negative selection 1997673
18588131 18588154 X - 26627737 HCT116 viability after 9 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.27320064210940853 [465] [88,113] -2 hSpCas9 negative selection 1997674
18595362 18595385 X - 26627737 HCT116 viability after 9 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 -0.7683485478753835 [266] [47,36] -5 hSpCas9 negative selection 1997675
18598480 18598503 X - 26627737 HCT116 viability after 9 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.1231356215180344 [510] [304,24] 0 hSpCas9 negative selection 1997676
18604634 18604657 X + 26627737 HCT116 viability after 9 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.07454862467004247 [648] [244,100] 0 hSpCas9 negative selection 1997677
18575433 18575456 X + 26627737 HCT116 viability after 12 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.5251385397202895 [41] [50,6,34] 5 hSpCas9 negative selection 2079987
18584305 18584328 X + 26627737 HCT116 viability after 12 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.0945059885311873 [434] [224,164,341] 1 hSpCas9 negative selection 2079988
18588131 18588154 X - 26627737 HCT116 viability after 12 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.13601353386078907 [118] [44,65,60] -1 hSpCas9 negative selection 2079989
18595362 18595385 X - 26627737 HCT116 viability after 12 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.308325705502892 [54] [58,118,38] 8 hSpCas9 negative selection 2079990
18598480 18598503 X - 26627737 HCT116 viability after 12 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.6222208810809923 [121] [31,101,167] 6 hSpCas9 negative selection 2079991
18604634 18604657 X + 26627737 HCT116 viability after 12 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.23430682951840198 [145] [105,32,128] 2 hSpCas9 negative selection 2079992
18575433 18575456 X + 26627737 HCT116 viability after 15 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.7603819885985423 [41] [14,27,75] 6 hSpCas9 negative selection 2162302
18584305 18584328 X + 26627737 HCT116 viability after 15 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.38478516568303456 [434] [203,211,544] 4 hSpCas9 negative selection 2162303
18588131 18588154 X - 26627737 HCT116 viability after 15 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.001336331672226132 [118] [60,48,93] 0 hSpCas9 negative selection 2162304
18595362 18595385 X - 26627737 HCT116 viability after 15 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.3322025956295285 [54] [59,78,96] 8 hSpCas9 negative selection 2162305
18598480 18598503 X - 26627737 HCT116 viability after 15 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.7425487833583275 [121] [96,116,134] 6 hSpCas9 negative selection 2162306
18604634 18604657 X + 26627737 HCT116 viability after 15 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.2910880066642526 [145] [117,34,155] 3 hSpCas9 negative selection 2162307
18575433 18575456 X + 26627737 HCT116 viability after 18 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.6040356192266925 [41] [77,47,59] 9 hSpCas9 negative selection 2244617
18584305 18584328 X + 26627737 HCT116 viability after 18 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.3023366903844422 [434] [96,128,574] 2 hSpCas9 negative selection 2244618
18588131 18588154 X - 26627737 HCT116 viability after 18 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.29691925902315286 [118] [18,70,48] -3 hSpCas9 negative selection 2244619
18595362 18595385 X - 26627737 HCT116 viability after 18 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.4330307029068603 [54] [30,108,72] 8 hSpCas9 negative selection 2244620
18598480 18598503 X - 26627737 HCT116 viability after 18 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.9039227964632901 [121] [83,61,191] 7 hSpCas9 negative selection 2244621
18604634 18604657 X + 26627737 HCT116 viability after 18 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.7537409185511028 [145] [220,68,67] 6 hSpCas9 negative selection 2244622
18507094 18507117 X + 24336569 HL60 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.07501643612900841 [562] [1254] 0 hSpCas9 negative selection 2256819
18507106 18507129 X - 24336569 HL60 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 -0.911129184411589 [390] [439] -7 hSpCas9 negative selection 2256820
18507124 18507147 X + 24336569 HL60 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 0.0363723896649617 [140] [305] 0 hSpCas9 negative selection 2256821
18510823 18510846 X - 24336569 HL60 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.3993013491714824 [774] [2162] 3 hSpCas9 negative selection 2256822
18510833 18510856 X + 24336569 HL60 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.28773781111756946 [1458] [3768] 2 hSpCas9 negative selection 2256823
18564473 18564496 X + 24336569 HL60 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.14134546543819804 [987] [2305] 1 hSpCas9 negative selection 2256824
18564491 18564514 X + 24336569 HL60 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 0.20768136427719996 [907] [2218] 2 hSpCas9 negative selection 2256825
18564501 18564524 X + 24336569 HL60 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.5939136953144784 [1071] [3423] 5 hSpCas9 negative selection 2256826
18575394 18575417 X + 24336569 HL60 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.28963005106235057 [524] [1357] 2 hSpCas9 negative selection 2256827
18575429 18575452 X + 24336569 HL60 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 -0.06031165988110976 [1150] [2335] 0 hSpCas9 negative selection 2256828
18507094 18507117 X + 24336569 KBM7 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.6166363637223149 [367] [1538] 5 hSpCas9 negative selection 2323996
18507106 18507129 X - 24336569 KBM7 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.44169398558458656 [378] [1403] 4 hSpCas9 negative selection 2323997
18507124 18507147 X + 24336569 KBM7 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 -0.9242712137415159 [246] [354] -6 hSpCas9 negative selection 2323998
18510823 18510846 X - 24336569 KBM7 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 1.189654051032107 [392] [2444] 8 hSpCas9 negative selection 2323999
18510833 18510856 X + 24336569 KBM7 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.8264299557560277 [1003] [4855] 7 hSpCas9 negative selection 2324000
18564473 18564496 X + 24336569 KBM7 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.6327804200974435 [514] [2177] 6 hSpCas9 negative selection 2324001
18564491 18564514 X + 24336569 KBM7 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 1.0507454680091073 [345] [1954] 8 hSpCas9 negative selection 2324002
18564501 18564524 X + 24336569 KBM7 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.38210709257875886 [1043] [3710] 3 hSpCas9 negative selection 2324003
18575394 18575417 X + 24336569 KBM7 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.027459692604657637 [676] [1881] 0 hSpCas9 negative selection 2324004
18575429 18575452 X + 24336569 KBM7 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 0.5019943220346919 [967] [3738] 4 hSpCas9 negative selection 2324005
18442066 18442089 X - 25494202 A375 resistance to PLX-4720 (puromycin) AAGCCTTCACTGTGACAGAAAGG CDKL5 ENSG00000008086 1.6731122921121888 [776,106] [463,136] 6 dCas9-VP64 positive selection 2391474
18442094 18442117 X - 25494202 A375 resistance to PLX-4720 (puromycin) ACTCTCCCCTATCTCCACTCAGG CDKL5 ENSG00000008086 -0.4519019400379476 [459,270] [97,14] -2 dCas9-VP64 positive selection 2391475
18442123 18442146 X + 25494202 A375 resistance to PLX-4720 (puromycin) AGGGTAGTGTCCAGCCTCTCAGG CDKL5 ENSG00000008086 -1.0090677703258166 [67,61] [8,3] -6 dCas9-VP64 positive selection 2391476
18471399 18471422 X + 25494202 A375 resistance to PLX-4720 (puromycin) GTCTTGTTCTGTTGCCCAGGCGG CDKL5 ENSG00000008086 -0.7436358345773786 [112,706] [22,87] -4 dCas9-VP64 positive selection 2407570
18449965 18449988 X + 25494202 A375 resistance to PLX-4720 (puromycin) TTGTATTTTTAGTAGAGTCGGGG CDKL5 ENSG00000008086 1.0128281800924883 [250,40] [67,58] 4 dCas9-VP64 positive selection 2417012
18475204 18475227 X - 25494202 A375 resistance to PLX-4720 (puromycin) AGCACTTTGGGAGGCCAAGGTGG CDKL5 ENSG00000008086 0.21234444010885142 [57,122] [21,23] 1 dCas9-VP64 positive selection 2422545
18611389 18611412 X + 25494202 A375 resistance to PLX-4720 (puromycin) CGCGCCACTGCACCCCAGCCTAG CDKL5 ENSG00000008086 0.36632392651586576 [208,84] [58,21] 1 dCas9-VP64 positive selection 2442343
18445119 18445142 X - 25494202 A375 resistance to PLX-4720 (puromycin) CGTGCCATTGCACTCCAGCCTAG CDKL5 ENSG00000008086 -0.5971814264096912 [233,130] [36,14] -3 dCas9-VP64 positive selection 2446968
18438139 18438162 X + 25494202 A375 resistance to PLX-4720 (puromycin) CACTGCAACCTCCGCCTCCCGAG CDKL5 ENSG00000008086 0.6259309833286419 [228,309] [35,151] 2 dCas9-VP64 positive selection 2450480
18528861 18528884 X - 25494202 A375 resistance to PLX-4720 (puromycin) TGGGAGGATCACTTGAGGCCCAG CDKL5 ENSG00000008086 3.7396651611807004 [3,72] [11,226] 9 dCas9-VP64 positive selection 2451772
18471400 18471423 X + 25494202 A375 resistance to PLX-4720 (puromycin) TCTTGTTCTGTTGCCCAGGCGGG CDKL5 ENSG00000008086 -0.6863317618464422 [59,137] [14,10] -3 dCas9-VP64 positive selection 2464094
18442066 18442089 X - 25494202 A375 resistance to PLX-4720 (zeocin) AAGCCTTCACTGTGACAGAAAGG CDKL5 ENSG00000008086 0.5382556778689539 [185,220] [128,65] 4 dCas9-VP64 positive selection 2486729
18442094 18442117 X - 25494202 A375 resistance to PLX-4720 (zeocin) ACTCTCCCCTATCTCCACTCAGG CDKL5 ENSG00000008086 -0.2823630229575005 [263,133] [68,38] -3 dCas9-VP64 positive selection 2486730
18442123 18442146 X + 25494202 A375 resistance to PLX-4720 (zeocin) AGGGTAGTGTCCAGCCTCTCAGG CDKL5 ENSG00000008086 -0.054977081068285916 [158,243] [36,86] 0 dCas9-VP64 positive selection 2486731
18471399 18471422 X + 25494202 A375 resistance to PLX-4720 (zeocin) GTCTTGTTCTGTTGCCCAGGCGG CDKL5 ENSG00000008086 1.9662405034468662 [80,153] [37,252] 8 dCas9-VP64 positive selection 2502825
18449965 18449988 X + 25494202 A375 resistance to PLX-4720 (zeocin) TTGTATTTTTAGTAGAGTCGGGG CDKL5 ENSG00000008086 -0.03815698815020019 [56,33] [21,6] 0 dCas9-VP64 positive selection 2512267
18475204 18475227 X - 25494202 A375 resistance to PLX-4720 (zeocin) AGCACTTTGGGAGGCCAAGGTGG CDKL5 ENSG00000008086 -0.9329704115466368 [100,219] [26,25] -8 dCas9-VP64 positive selection 2517800
18611389 18611412 X + 25494202 A375 resistance to PLX-4720 (zeocin) CGCGCCACTGCACCCCAGCCTAG CDKL5 ENSG00000008086 -0.6605575882505516 [226,108] [36,31] -6 dCas9-VP64 positive selection 2537598
18445119 18445142 X - 25494202 A375 resistance to PLX-4720 (zeocin) CGTGCCATTGCACTCCAGCCTAG CDKL5 ENSG00000008086 0.14726127288975888 [140,101] [59,28] 1 dCas9-VP64 positive selection 2542223
18438139 18438162 X + 25494202 A375 resistance to PLX-4720 (zeocin) CACTGCAACCTCCGCCTCCCGAG CDKL5 ENSG00000008086 0.8832307312434098 [227,267] [69,222] 6 dCas9-VP64 positive selection 2545735
18528861 18528884 X - 25494202 A375 resistance to PLX-4720 (zeocin) TGGGAGGATCACTTGAGGCCCAG CDKL5 ENSG00000008086 0.5989374680558959 [87,40] [52,11] 4 dCas9-VP64 positive selection 2547027
18471400 18471423 X + 25494202 A375 resistance to PLX-4720 (zeocin) TCTTGTTCTGTTGCCCAGGCGGG CDKL5 ENSG00000008086 -0.6931781766025115 [37,108] [16,10] -6 dCas9-VP64 positive selection 2559349
18587966 18587989 X + 27260157 DLD1 viability AAAGTCCGTGGACATGTGGTCGG CDKL5 ENSG00000008086 0.485383204757091 [] [] 8 hSpCas9 negative selection 2574058
18507094 18507117 X + 27260157 DLD1 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 1.10102885532716 [] [] 9 hSpCas9 negative selection 2575080
18598532 18598555 X - 27260157 DLD1 viability AGAACGATCCAGAAGTCTCTGGG CDKL5 ENSG00000008086 0.517984098336193 [] [] 8 hSpCas9 negative selection 2580721
18587982 18588005 X + 27260157 DLD1 viability TGGTCGGTGGGCTGTATTCTTGG CDKL5 ENSG00000008086 -0.13665521901643 [] [] -1 hSpCas9 negative selection 2581097
18564491 18564514 X + 27260157 DLD1 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 0.53342068703449 [] [] 8 hSpCas9 negative selection 2581170
18507124 18507147 X + 27260157 DLD1 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 0.522520489877 [] [] 8 hSpCas9 negative selection 2584949
18564473 18564496 X + 27260157 DLD1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.0954158611317673 [] [] 3 hSpCas9 negative selection 2586224
18575429 18575452 X + 27260157 DLD1 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 -0.117198638494621 [] [] -1 hSpCas9 negative selection 2611315
18564501 18564524 X + 27260157 DLD1 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.459035245268514 [] [] 7 hSpCas9 negative selection 2611791
18603957 18603980 X + 27260157 DLD1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.499847781588012 [] [] 8 hSpCas9 negative selection 2614857
18510833 18510856 X + 27260157 DLD1 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.230275009928442 [] [] 3 hSpCas9 negative selection 2615973
18575432 18575455 X + 27260157 DLD1 viability TGAAGGAAGCATTTCGTCGGAGG CDKL5 ENSG00000008086 1.00376423648293 [] [] 9 hSpCas9 negative selection 2616127
18510823 18510846 X - 27260157 DLD1 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.303263843770974 [] [] 4 hSpCas9 negative selection 2620377
18588123 18588146 X - 27260157 DLD1 viability ACCCGGAGCCCATGGAAGCGAGG CDKL5 ENSG00000008086 1.02711483450661 [] [] 9 hSpCas9 negative selection 2621861
18584305 18584328 X + 27260157 DLD1 viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.422894396725449 [] [] 7 hSpCas9 negative selection 2622021
18507106 18507129 X - 27260157 DLD1 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.164362700497132 [] [] 3 hSpCas9 negative selection 2644399
18598541 18598564 X + 27260157 DLD1 viability TTCTGGATCGTTCTCCTTCAAGG CDKL5 ENSG00000008086 0.357743908898621 [] [] 4 hSpCas9 negative selection 2644547
18587954 18587977 X + 27260157 DLD1 viability CGCTCCCTATGGAAAGTCCGTGG CDKL5 ENSG00000008086 0.297404916569851 [] [] 4 hSpCas9 negative selection 2645334
18575394 18575417 X + 27260157 DLD1 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.869570643892798 [] [] 9 hSpCas9 negative selection 2645807
18603967 18603990 X + 27260157 DLD1 viability ACCTGAGTGTAGGCCTGCCCCGG CDKL5 ENSG00000008086 0.508106384435533 [] [] 8 hSpCas9 negative selection 2647369
18587966 18587989 X + 27260157 HT1080 viability AAAGTCCGTGGACATGTGGTCGG CDKL5 ENSG00000008086 0.603279091464094 [] [] 5 hSpCas9 negative selection 2650188
18507094 18507117 X + 27260157 HT1080 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 1.22510230853312 [] [] 8 hSpCas9 negative selection 2651210
18598532 18598555 X - 27260157 HT1080 viability AGAACGATCCAGAAGTCTCTGGG CDKL5 ENSG00000008086 0.580965244834242 [] [] 5 hSpCas9 negative selection 2656851
18587982 18588005 X + 27260157 HT1080 viability TGGTCGGTGGGCTGTATTCTTGG CDKL5 ENSG00000008086 -0.0975546941093378 [] [] 0 hSpCas9 negative selection 2657227
18564491 18564514 X + 27260157 HT1080 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 -0.547959342789373 [] [] -7 hSpCas9 negative selection 2657300
18507124 18507147 X + 27260157 HT1080 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 1.23826435319061 [] [] 8 hSpCas9 negative selection 2661079
18564473 18564496 X + 27260157 HT1080 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.104098492265391 [] [] 1 hSpCas9 negative selection 2662354
18575429 18575452 X + 27260157 HT1080 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 -0.00920367535104787 [] [] 0 hSpCas9 negative selection 2687445
18564501 18564524 X + 27260157 HT1080 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.719330287042199 [] [] 6 hSpCas9 negative selection 2687921
18603957 18603980 X + 27260157 HT1080 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.691589404815599 [] [] 6 hSpCas9 negative selection 2690987
18510833 18510856 X + 27260157 HT1080 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.196692235078682 [] [] 1 hSpCas9 negative selection 2692103
18575432 18575455 X + 27260157 HT1080 viability TGAAGGAAGCATTTCGTCGGAGG CDKL5 ENSG00000008086 0.569486037653251 [] [] 5 hSpCas9 negative selection 2692257
18510823 18510846 X - 27260157 HT1080 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.604120567527794 [] [] 5 hSpCas9 negative selection 2696507
18588123 18588146 X - 27260157 HT1080 viability ACCCGGAGCCCATGGAAGCGAGG CDKL5 ENSG00000008086 0.838473177071299 [] [] 7 hSpCas9 negative selection 2697991
18584305 18584328 X + 27260157 HT1080 viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.86631434363237 [] [] 7 hSpCas9 negative selection 2698151
18507106 18507129 X - 27260157 HT1080 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.858959613983636 [] [] 7 hSpCas9 negative selection 2720529
18598541 18598564 X + 27260157 HT1080 viability TTCTGGATCGTTCTCCTTCAAGG CDKL5 ENSG00000008086 1.11883739061374 [] [] 8 hSpCas9 negative selection 2720677
18587954 18587977 X + 27260157 HT1080 viability CGCTCCCTATGGAAAGTCCGTGG CDKL5 ENSG00000008086 0.295385737969032 [] [] 2 hSpCas9 negative selection 2721464
18575394 18575417 X + 27260157 HT1080 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.941122605150518 [] [] 7 hSpCas9 negative selection 2721937
18603967 18603990 X + 27260157 HT1080 viability ACCTGAGTGTAGGCCTGCCCCGG CDKL5 ENSG00000008086 -0.00322236395175185 [] [] 0 hSpCas9 negative selection 2723499
18587966 18587989 X + 27260157 MKN45 viability AAAGTCCGTGGACATGTGGTCGG CDKL5 ENSG00000008086 -0.583042818229423 [] [] -6 hSpCas9 negative selection 2726318
18507094 18507117 X + 27260157 MKN45 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.676939744380482 [] [] 7 hSpCas9 negative selection 2727340
18598532 18598555 X - 27260157 MKN45 viability AGAACGATCCAGAAGTCTCTGGG CDKL5 ENSG00000008086 -0.0521273649928793 [] [] 0 hSpCas9 negative selection 2732981
18587982 18588005 X + 27260157 MKN45 viability TGGTCGGTGGGCTGTATTCTTGG CDKL5 ENSG00000008086 0.475572819251619 [] [] 6 hSpCas9 negative selection 2733357
18564491 18564514 X + 27260157 MKN45 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 -0.156324748086894 [] [] 0 hSpCas9 negative selection 2733430
18507124 18507147 X + 27260157 MKN45 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 0.224328887324894 [] [] 5 hSpCas9 negative selection 2737209
18564473 18564496 X + 27260157 MKN45 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.552031046581844 [] [] 7 hSpCas9 negative selection 2738484
18575429 18575452 X + 27260157 MKN45 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 0.482636452812452 [] [] 6 hSpCas9 negative selection 2763575
18564501 18564524 X + 27260157 MKN45 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 1.02514155662907 [] [] 8 hSpCas9 negative selection 2764051
18603957 18603980 X + 27260157 MKN45 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.212925418367703 [] [] -1 hSpCas9 negative selection 2767117
18510833 18510856 X + 27260157 MKN45 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.218660784589213 [] [] 5 hSpCas9 negative selection 2768233
18575432 18575455 X + 27260157 MKN45 viability TGAAGGAAGCATTTCGTCGGAGG CDKL5 ENSG00000008086 0.498659109395754 [] [] 6 hSpCas9 negative selection 2768387
18510823 18510846 X - 27260157 MKN45 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.306997088205064 [] [] 5 hSpCas9 negative selection 2772637
18588123 18588146 X - 27260157 MKN45 viability ACCCGGAGCCCATGGAAGCGAGG CDKL5 ENSG00000008086 1.18684978108291 [] [] 9 hSpCas9 negative selection 2774121
18584305 18584328 X + 27260157 MKN45 viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.643012957245264 [] [] 7 hSpCas9 negative selection 2774281
18507106 18507129 X - 27260157 MKN45 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.773361973027406 [] [] 7 hSpCas9 negative selection 2796659
18598541 18598564 X + 27260157 MKN45 viability TTCTGGATCGTTCTCCTTCAAGG CDKL5 ENSG00000008086 -0.0515657368931269 [] [] 0 hSpCas9 negative selection 2796807
18587954 18587977 X + 27260157 MKN45 viability CGCTCCCTATGGAAAGTCCGTGG CDKL5 ENSG00000008086 0.402920352036249 [] [] 6 hSpCas9 negative selection 2797594
18575394 18575417 X + 27260157 MKN45 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.818794623432577 [] [] 8 hSpCas9 negative selection 2798067
18603967 18603990 X + 27260157 MKN45 viability ACCTGAGTGTAGGCCTGCCCCGG CDKL5 ENSG00000008086 -0.138964819799987 [] [] 0 hSpCas9 negative selection 2799629
18587966 18587989 X + 27260157 RKO viability AAAGTCCGTGGACATGTGGTCGG CDKL5 ENSG00000008086 0.357021130634171 [] [] 2 hSpCas9 negative selection 2802448
18507094 18507117 X + 27260157 RKO viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 1.2577428352963 [] [] 9 hSpCas9 negative selection 2803470
18598532 18598555 X - 27260157 RKO viability AGAACGATCCAGAAGTCTCTGGG CDKL5 ENSG00000008086 1.43633274495791 [] [] 9 hSpCas9 negative selection 2809111
18587982 18588005 X + 27260157 RKO viability TGGTCGGTGGGCTGTATTCTTGG CDKL5 ENSG00000008086 -0.439767363454084 [] [] -6 hSpCas9 negative selection 2809487
18564491 18564514 X + 27260157 RKO viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 0.037075319808268 [] [] 0 hSpCas9 negative selection 2809560
18507124 18507147 X + 27260157 RKO viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 1.2048373667046 [] [] 9 hSpCas9 negative selection 2813339
18564473 18564496 X + 27260157 RKO viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.0183016758729056 [] [] 0 hSpCas9 negative selection 2814614
18575429 18575452 X + 27260157 RKO viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 0.0157443229489514 [] [] 0 hSpCas9 negative selection 2839705
18564501 18564524 X + 27260157 RKO viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 1.45798643707136 [] [] 9 hSpCas9 negative selection 2840181
18603957 18603980 X + 27260157 RKO viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 1.04666400178118 [] [] 9 hSpCas9 negative selection 2843247
18510833 18510856 X + 27260157 RKO viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.519599285854321 [] [] 2 hSpCas9 negative selection 2844363
18575432 18575455 X + 27260157 RKO viability TGAAGGAAGCATTTCGTCGGAGG CDKL5 ENSG00000008086 0.232830227490583 [] [] 1 hSpCas9 negative selection 2844517
18510823 18510846 X - 27260157 RKO viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.121843728283106 [] [] 0 hSpCas9 negative selection 2848767
18588123 18588146 X - 27260157 RKO viability ACCCGGAGCCCATGGAAGCGAGG CDKL5 ENSG00000008086 1.16156936453302 [] [] 9 hSpCas9 negative selection 2850251
18584305 18584328 X + 27260157 RKO viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.441740341263917 [] [] 2 hSpCas9 negative selection 2850411
18507106 18507129 X - 27260157 RKO viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.569453843370005 [] [] 3 hSpCas9 negative selection 2872789
18598541 18598564 X + 27260157 RKO viability TTCTGGATCGTTCTCCTTCAAGG CDKL5 ENSG00000008086 0.764280023466174 [] [] 8 hSpCas9 negative selection 2872937
18587954 18587977 X + 27260157 RKO viability CGCTCCCTATGGAAAGTCCGTGG CDKL5 ENSG00000008086 0.220747897106826 [] [] 1 hSpCas9 negative selection 2873724
18575394 18575417 X + 27260157 RKO viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.269764088114058 [] [] 1 hSpCas9 negative selection 2874197
18603967 18603990 X + 27260157 RKO viability ACCTGAGTGTAGGCCTGCCCCGG CDKL5 ENSG00000008086 0.890787952446787 [] [] 8 hSpCas9 negative selection 2875759
18587966 18587989 X + 27260157 SF268 viability AAAGTCCGTGGACATGTGGTCGG CDKL5 ENSG00000008086 -0.0930705725164542 [] [] 0 hSpCas9 negative selection 2878578
18507094 18507117 X + 27260157 SF268 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.515713051338455 [] [] 8 hSpCas9 negative selection 2879600
18598532 18598555 X - 27260157 SF268 viability AGAACGATCCAGAAGTCTCTGGG CDKL5 ENSG00000008086 1.01865564160475 [] [] 9 hSpCas9 negative selection 2885241
18587982 18588005 X + 27260157 SF268 viability TGGTCGGTGGGCTGTATTCTTGG CDKL5 ENSG00000008086 -0.174511412625727 [] [] -1 hSpCas9 negative selection 2885617
18564491 18564514 X + 27260157 SF268 viability TGTGGCGATCAAGAAATTCAAGG CDKL5 ENSG00000008086 0.237488192812052 [] [] 3 hSpCas9 negative selection 2885690
18507124 18507147 X + 27260157 SF268 viability ATGAATAAATTTGAGATCCTTGG CDKL5 ENSG00000008086 1.05789596588792 [] [] 9 hSpCas9 negative selection 2889469
18564473 18564496 X + 27260157 SF268 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.371916017197557 [] [] 4 hSpCas9 negative selection 2890744
18575429 18575452 X + 27260157 SF268 viability AGTTGAAGGAAGCATTTCGTCGG CDKL5 ENSG00000008086 0.52724029436937 [] [] 8 hSpCas9 negative selection 2915835
18564501 18564524 X + 27260157 SF268 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 1.0770665139499 [] [] 9 hSpCas9 negative selection 2916311
18603957 18603980 X + 27260157 SF268 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 1.03950533747993 [] [] 9 hSpCas9 negative selection 2919377
18510833 18510856 X + 27260157 SF268 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.57599918906717 [] [] 8 hSpCas9 negative selection 2920493
18575432 18575455 X + 27260157 SF268 viability TGAAGGAAGCATTTCGTCGGAGG CDKL5 ENSG00000008086 0.318885633314765 [] [] 4 hSpCas9 negative selection 2920647
18510823 18510846 X - 27260157 SF268 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 1.01512085032506 [] [] 9 hSpCas9 negative selection 2924897
18588123 18588146 X - 27260157 SF268 viability ACCCGGAGCCCATGGAAGCGAGG CDKL5 ENSG00000008086 1.06438941992262 [] [] 9 hSpCas9 negative selection 2926381
18584305 18584328 X + 27260157 SF268 viability CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.0832274351916585 [] [] 0 hSpCas9 negative selection 2926541
18507106 18507129 X - 27260157 SF268 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.491420153344659 [] [] 7 hSpCas9 negative selection 2948919
18598541 18598564 X + 27260157 SF268 viability TTCTGGATCGTTCTCCTTCAAGG CDKL5 ENSG00000008086 0.538274882836156 [] [] 8 hSpCas9 negative selection 2949067
18587954 18587977 X + 27260157 SF268 viability CGCTCCCTATGGAAAGTCCGTGG CDKL5 ENSG00000008086 0.279416809538377 [] [] 4 hSpCas9 negative selection 2949854
18575394 18575417 X + 27260157 SF268 viability AATGCTTCGGACTCTCAAGCAGG CDKL5 ENSG00000008086 0.576127501834745 [] [] 8 hSpCas9 negative selection 2950327
18603967 18603990 X + 27260157 SF268 viability ACCTGAGTGTAGGCCTGCCCCGG CDKL5 ENSG00000008086 0.234981948116285 [] [] 3 hSpCas9 negative selection 2951889
18598584 18598607 X - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 -0.03568148799770862 [3,4] [4,2] 0 hSpCas9 positive selection 2978253
18587958 18587981 X - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 0.021974488319856572 [3,2] [2,2] 0 hSpCas9 positive selection 2978254
18584306 18584329 X + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.12348900058585743 [5,5] [4,4] 2 hSpCas9 positive selection 2978255
18603984 18604007 X - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 -1.3688487289289988 [2,1] [0,0] -9 hSpCas9 positive selection 2978256
18598584 18598607 X - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 0.19817974235038113 [3,3] [4,2] 3 hSpCas9 positive selection 3046111
18587958 18587981 X - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 0.3308170536800151 [3,3] [3,2] 6 hSpCas9 positive selection 3046112
18584306 18584329 X + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.38336561260763236 [5,5] [5,4] 6 hSpCas9 positive selection 3046113
18603984 18604007 X - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 0.08996179004297944 [2,2] [0,1] 1 hSpCas9 positive selection 3046114
18510823 18510846 - 24336571 A375 resistance to PLX after 7 days GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.293814569855263 [9,8] [13,9] 7 hSpCas9 positive selection 3104677
18507141 18507164 - 24336571 A375 resistance to PLX after 7 days TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.29629398439824534 [16,14] [13,11] -8 hSpCas9 positive selection 3104678
18510833 18510856 + 24336571 A375 resistance to PLX after 7 days TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.048577173739226154 [11,9] [11,10] 1 hSpCas9 positive selection 3104679
18507094 18507117 + 24336571 A375 resistance to PLX after 7 days TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 -0.10626119235260312 [29,36] [29,30] -3 hSpCas9 positive selection 3104680
18510823 18510846 - 24336571 A375 resistance to PLX after 14 days GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.011515510350171287 [10,10] [5,2] 0 hSpCas9 positive selection 3162470
18507141 18507164 - 24336571 A375 resistance to PLX after 14 days TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.332545767077112 [17,12] [4,5] -4 hSpCas9 positive selection 3162471
18510833 18510856 + 24336571 A375 resistance to PLX after 14 days TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 1.2288080746840142 [9,13] [10,15] 8 hSpCas9 positive selection 3162472
18507094 18507117 + 24336571 A375 resistance to PLX after 14 days TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 -0.14622905156279709 [32,25] [13,9] -1 hSpCas9 positive selection 3162473
18510823 18510846 - 24336571 A375 viability after 7 days GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.6533443253451185 [15] [9,8] -7 hSpCas9 negative selection 3220263
18507141 18507164 - 24336571 A375 viability after 7 days TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.8833169032620074 [31] [16,14] -8 hSpCas9 negative selection 3220264
18510833 18510856 + 24336571 A375 viability after 7 days TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.057987121675240644 [10] [11,9] 0 hSpCas9 negative selection 3220265
18507094 18507117 + 24336571 A375 viability after 7 days TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 -0.11367003918961638 [37] [29,36] -2 hSpCas9 negative selection 3220266
18510823 18510846 - 24336571 A375 viability after 14 days GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.47618944576169075 [15] [10,10] -5 hSpCas9 negative selection 3278056
18507141 18507164 - 24336571 A375 viability after 14 days TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.9476340849784552 [31] [17,12] -8 hSpCas9 negative selection 3278057
18510833 18510856 + 24336571 A375 viability after 14 days TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.24329428341196607 [10] [9,13] 3 hSpCas9 negative selection 3278058
18507094 18507117 + 24336571 A375 viability after 14 days TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 -0.26440668943331636 [37] [32,25] -3 hSpCas9 negative selection 3278059
18507094 18507117 X + 27383988 293T resistance to West Nile virus (flavivirus) TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 -1.0034165585564916 [338,273] [0,0] -6 hSpCas9 positive selection 3342459
18507106 18507129 X - 27383988 293T resistance to West Nile virus (flavivirus) TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 -0.716817870946318 [892,866] [0,5] -5 hSpCas9 positive selection 3342460
18510823 18510846 X - 27383988 293T resistance to West Nile virus (flavivirus) GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 1.9168166908167468 [389,338] [0,16] 7 hSpCas9 positive selection 3342461
18564473 18564496 X + 27383988 293T resistance to West Nile virus (flavivirus) GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 -0.44311350669525723 [207,207] [0,0] -3 hSpCas9 positive selection 3361693
18510833 18510856 X + 27383988 293T resistance to West Nile virus (flavivirus) TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.9374306429764127 [292,292] [0,0] -6 hSpCas9 positive selection 3361694
18564501 18564524 X + 27383988 293T resistance to West Nile virus (flavivirus) AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.19123702098806272 [133,133] [0,0] 1 hSpCas9 positive selection 3361695
18598584 18598607 X - 26780180 HT29 viability (Avana library 4 designs) ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 0.595060305632765 [] [] 2 hSpCas9 negative selection 3414566
18587958 18587981 X - 26780180 HT29 viability (Avana library 4 designs) ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 1.47151261911903 [] [] 6 hSpCas9 negative selection 3414567
18584305 18584328 X + 26780180 HT29 viability (Avana library 4 designs) CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.00793532470233282 [] [] 0 hSpCas9 negative selection 3414568
18603984 18604007 X - 26780180 HT29 viability (Avana library 4 designs) GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 0.682065962552236 [] [] 2 hSpCas9 negative selection 3414569
18598584 18598607 X - 26780180 A375 viability (Avana lentiCRISPRv2) ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 1.76223551036185 [] [] 2 hSpCas9 negative selection 3491146
18587958 18587981 X - 26780180 A375 viability (Avana lentiCRISPRv2) ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 5.00754165033595 [] [] 8 hSpCas9 negative selection 3491147
18584305 18584328 X + 26780180 A375 viability (Avana lentiCRISPRv2) CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 5.75044148030587 [] [] 9 hSpCas9 negative selection 3491148
18603984 18604007 X - 26780180 A375 viability (Avana lentiCRISPRv2) GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 5.02309935950454 [] [] 8 hSpCas9 negative selection 3491149
18579860 18579883 X + 26780180 A375 viability (Avana lentiCRISPRv2) TTGCTGGAAGAAATGCCAAATGG CDKL5 ENSG00000008086 0.542273927107735 [] [] 0 hSpCas9 negative selection 3491150
18507141 18507164 X - 26780180 A375 viability (Avana lentiCRISPRv2) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.888207039934153 [] [] -1 hSpCas9 negative selection 3491151
18598584 18598607 X - 26780180 A375 viability (Avana lentiGuide) ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 0.520654058772215 [] [] 0 hSpCas9 negative selection 3599805
18587958 18587981 X - 26780180 A375 viability (Avana lentiGuide) ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 -3.69412694375123 [] [] -6 hSpCas9 negative selection 3599806
18584305 18584328 X + 26780180 A375 viability (Avana lentiGuide) CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 -3.48544073157753 [] [] -6 hSpCas9 negative selection 3599807
18603984 18604007 X - 26780180 A375 viability (Avana lentiGuide) GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 8.33976297316109 [] [] 6 hSpCas9 negative selection 3599808
18579860 18579883 X + 26780180 A375 viability (Avana lentiGuide) TTGCTGGAAGAAATGCCAAATGG CDKL5 ENSG00000008086 -3.53226218569882 [] [] -6 hSpCas9 negative selection 3599809
18507141 18507164 X - 26780180 A375 viability (Avana lentiGuide) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -5.26211560863202 [] [] -8 hSpCas9 negative selection 3599810
18598584 18598607 X - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 0.11571852972673229 [5] [5,5] 3 hSpCas9 positive selection 3708464
18587958 18587981 X - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 0.061251845192930636 [5] [5,4] 1 hSpCas9 positive selection 3708465
18584305 18584328 X + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.22229681655930572 [5] [6,6] 6 hSpCas9 positive selection 3708466
18603984 18604007 X - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 0.27386724467120876 [3] [5,4] 7 hSpCas9 positive selection 3708467
18579860 18579883 X + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTGCTGGAAGAAATGCCAAATGG CDKL5 ENSG00000008086 -0.3354138275368325 [4] [5,1] -5 hSpCas9 positive selection 3708468
18507141 18507164 X - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.11158343116776798 [5] [4,4] -2 hSpCas9 positive selection 3708469
18598584 18598607 X - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACAATGTGCTGCTTTCCACATGG CDKL5 ENSG00000008086 0.3004901444214326 [5] [6,5] 8 hSpCas9 positive selection 3817071
18587958 18587981 X - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATGTCCACGGACTTTCCATAGGG CDKL5 ENSG00000008086 -0.43665670441618143 [5] [2,3] -5 hSpCas9 positive selection 3817072
18584305 18584328 X + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.24315453225785633 [7] [7,6] 6 hSpCas9 positive selection 3817073
18603984 18604007 X - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GGGAGACCTTCGTCAGCCCGGGG CDKL5 ENSG00000008086 -0.16305663381569674 [4] [2,3] -2 hSpCas9 positive selection 3817074
18579860 18579883 X + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTGCTGGAAGAAATGCCAAATGG CDKL5 ENSG00000008086 0.30815632309148633 [4] [4,4] 8 hSpCas9 positive selection 3817075
18507141 18507164 X - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 0.3195027321052007 [5] [6,5] 8 hSpCas9 positive selection 3817076
18564501 18564524 X + 26780180 A375 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.615471028809362 [] [] 2 hSpCas9 negative selection 3925253
18564473 18564496 X + 26780180 A375 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.654611219913935 [] [] 2 hSpCas9 negative selection 3925254
18510823 18510846 X - 26780180 A375 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.464767851624952 [] [] 1 hSpCas9 negative selection 3925255
18510833 18510856 X + 26780180 A375 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 1.24644638051238 [] [] 6 hSpCas9 negative selection 3925256
18507106 18507129 X - 26780180 A375 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 -0.270846463625537 [] [] -7 hSpCas9 negative selection 3925257
18507094 18507117 X + 26780180 A375 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.664858501210113 [] [] 2 hSpCas9 negative selection 3925258
18564501 18564524 X + 26780180 HT29 viability (GeCKOv2 library) AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.950175986251743 [] [] 4 hSpCas9 negative selection 4033219
18564473 18564496 X + 26780180 HT29 viability (GeCKOv2 library) GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 1.58922578083631 [] [] 8 hSpCas9 negative selection 4033220
18510823 18510846 X - 26780180 HT29 viability (GeCKOv2 library) GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.275000207237737 [] [] 0 hSpCas9 negative selection 4033221
18510833 18510856 X + 26780180 HT29 viability (GeCKOv2 library) TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 1.54830875461604 [] [] 7 hSpCas9 negative selection 4033222
18507106 18507129 X - 26780180 HT29 viability (GeCKOv2 library) TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 -0.263067099754177 [] [] -6 hSpCas9 negative selection 4033223
18507094 18507117 X + 26780180 HT29 viability (GeCKOv2 library) TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.82078910539799 [] [] 3 hSpCas9 negative selection 4033224
18510823 18510846 X - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.10053133029301423 [3] [1,2] -2 hSpCas9 positive selection 4126706
18507141 18507164 X - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.02452130534288698 [3] [2,2] 0 hSpCas9 positive selection 4126707
18510833 18510856 X + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.2474783648587574 [3] [1,3] 6 hSpCas9 positive selection 4126708
18507094 18507117 X + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.10196074326806642 [4] [3,3] 2 hSpCas9 positive selection 4126709
18510823 18510846 X - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.18269408142083746 [4] [0,4,3,0] 1 hSpCas9 positive selection 4190728
18507141 18507164 X - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TACCTTCACCTACAACCCCAAGG CDKL5 ENSG00000008086 -0.3923545410830005 [4] [2,0,1,0] -6 hSpCas9 positive selection 4190729
18510833 18510856 X + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.13546267227452552 [3] [3,2,1,0] 1 hSpCas9 positive selection 4190730
18507094 18507117 X + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 1.0470860651098917 [4] [3,5,3,4] 7 hSpCas9 positive selection 4190731
18507094 18507117 X + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.19015970757641387 [4] [3,3] 4 hSpCas9 positive selection 4262515
18507106 18507129 X - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.44089527084847613 [5] [5,5] 8 hSpCas9 positive selection 4262516
18510823 18510846 X - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.328181786197274 [4] [4,3] 6 hSpCas9 positive selection 4262517
18564473 18564496 X + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.5523828915304356 [2] [2,3] 9 hSpCas9 positive selection 4326793
18510833 18510856 X + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.01204805773440315 [3] [3,1] 0 hSpCas9 positive selection 4326794
18564501 18564524 X + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 -0.058792851648402256 [2] [3,0] -1 hSpCas9 positive selection 4326795
18603905 18603927 X - 27760321 OCIAML3 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.44670186730634154 [818,772] [840,859] 5 hSpCas9 negative selection 4388141
18604034 18604056 X - 27760321 OCIAML3 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.4926959693499093 [366,315] [316,449] 6 hSpCas9 negative selection 4388142
18604435 18604457 X - 27760321 OCIAML3 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 -0.019760715675249937 [473,441] [237,503] 0 hSpCas9 negative selection 4388143
18575435 18575457 X + 27760321 OCIAML3 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 0.8650637387079855 [491,393] [494,799] 8 hSpCas9 negative selection 4388144
18584266 18584288 X + 27760321 OCIAML3 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.7161794997133438 [342,249] [263,524] 8 hSpCas9 negative selection 4388145
18603905 18603927 X - 27760321 OCIAML2 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.7515650038061693 [818,772] [1107,1054] 8 hSpCas9 negative selection 4471604
18604034 18604056 X - 27760321 OCIAML2 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 1.2512008365890597 [366,315] [568,769] 9 hSpCas9 negative selection 4471605
18604435 18604457 X - 27760321 OCIAML2 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.3855318283086618 [473,441] [453,523] 5 hSpCas9 negative selection 4471606
18575435 18575457 X + 27760321 OCIAML2 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 0.8043195949196449 [491,393] [550,715] 9 hSpCas9 negative selection 4471607
18584266 18584288 X + 27760321 OCIAML2 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.13607216906714986 [342,249] [169,380] 1 hSpCas9 negative selection 4471608
18603905 18603927 X - 27760321 MV411 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 1.1848337731089882 [818,772] [1012,1468] 8 hSpCas9 negative selection 4555067
18604034 18604056 X - 27760321 MV411 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 -0.17722844387378522 [366,315] [123,310] -1 hSpCas9 negative selection 4555068
18604435 18604457 X - 27760321 MV411 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.889528905250085 [473,441] [492,660] 6 hSpCas9 negative selection 4555069
18575435 18575457 X + 27760321 MV411 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.9171203050017774 [491,393] [49,309] -6 hSpCas9 negative selection 4555070
18584266 18584288 X + 27760321 MV411 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 1.1907578469776292 [342,249] [630,158] 8 hSpCas9 negative selection 4555071
18603905 18603927 X - 27760321 HL60 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.6237576368489764 [818,772] [1146,849] 7 hSpCas9 negative selection 4638530
18604034 18604056 X - 27760321 HL60 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.6084539507999978 [366,315] [410,437] 7 hSpCas9 negative selection 4638531
18604435 18604457 X - 27760321 HL60 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.7695207634454805 [473,441] [738,530] 8 hSpCas9 negative selection 4638532
18575435 18575457 X + 27760321 HL60 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 0.6124505910071939 [491,393] [501,600] 7 hSpCas9 negative selection 4638533
18584266 18584288 X + 27760321 HL60 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.6976498690021579 [342,249] [423,351] 7 hSpCas9 negative selection 4638534
18603905 18603927 X - 27760321 HT1080 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 -0.4531154154070663 [772,602] [235,160] -2 hSpCas9 negative selection 4721993
18604034 18604056 X - 27760321 HT1080 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.3797576924144161 [315,246] [196,89] 2 hSpCas9 negative selection 4721994
18604435 18604457 X - 27760321 HT1080 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 -1.075437913231142 [441,344] [71,76] -4 hSpCas9 negative selection 4721995
18575435 18575457 X + 27760321 HT1080 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 2.526351493244304 [393,307] [597,1032] 9 hSpCas9 negative selection 4721996
18584266 18584288 X + 27760321 HT1080 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 2.5498186777938963 [249,194] [613,414] 9 hSpCas9 negative selection 4721997
18603905 18603927 X - 27760321 HT29 viability after 7 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.2209284299389802 [772,602] [1342,832,961] 3 hSpCas9 negative selection 4805456
18604034 18604056 X - 27760321 HT29 viability after 7 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.5918564169779534 [315,246] [730,344,584] 8 hSpCas9 negative selection 4805457
18604435 18604457 X - 27760321 HT29 viability after 7 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 -0.158019104482575 [441,344] [500,492,374] -2 hSpCas9 negative selection 4805458
18575435 18575457 X + 27760321 HT29 viability after 7 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.2349801607885254 [393,307] [501,286,377] -3 hSpCas9 negative selection 4805459
18584266 18584288 X + 27760321 HT29 viability after 7 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.12178669080446647 [249,194] [428,269,252] 1 hSpCas9 negative selection 4805460
18603905 18603927 X - 27760321 HT29 viability after 25 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.5496657905113402 [772,602] [1184,1221,1028] 6 hSpCas9 negative selection 4888919
18604034 18604056 X - 27760321 HT29 viability after 25 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.9013285710821708 [315,246] [543,655,605] 9 hSpCas9 negative selection 4888920
18604435 18604457 X - 27760321 HT29 viability after 25 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.34731274163132225 [441,344] [526,526,674] 3 hSpCas9 negative selection 4888921
18575435 18575457 X + 27760321 HT29 viability after 25 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.07483173263674775 [393,307] [299,355,503] -1 hSpCas9 negative selection 4888922
18584266 18584288 X + 27760321 HT29 viability after 25 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 -0.022509731299193203 [249,194] [212,297,240] 0 hSpCas9 negative selection 4888923
18603905 18603927 X - 27760321 HT29 viability after 22 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.5382682500226048 [772,602] [1239,1139,1081] 6 hSpCas9 negative selection 4972382
18604034 18604056 X - 27760321 HT29 viability after 22 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 1.0806799192740086 [315,246] [602,811,651] 9 hSpCas9 negative selection 4972383
18604435 18604457 X - 27760321 HT29 viability after 22 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.5584717128715495 [441,344] [717,569,720] 6 hSpCas9 negative selection 4972384
18575435 18575457 X + 27760321 HT29 viability after 22 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.15140957926453383 [393,307] [234,358,506] -1 hSpCas9 negative selection 4972385
18584266 18584288 X + 27760321 HT29 viability after 22 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.18502913188164716 [249,194] [185,410,282] 1 hSpCas9 negative selection 4972386
18603905 18603927 X - 27760321 HT29 viability after 19 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.8142043496501046 [772,602] [1230,1690,1217] 8 hSpCas9 negative selection 5055845
18604034 18604056 X - 27760321 HT29 viability after 19 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.5985840058703109 [315,246] [452,606,401] 6 hSpCas9 negative selection 5055846
18604435 18604457 X - 27760321 HT29 viability after 19 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.23318875820452606 [441,344] [467,737,379] 2 hSpCas9 negative selection 5055847
18575435 18575457 X + 27760321 HT29 viability after 19 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.07319085022274568 [393,307] [446,391,314] 0 hSpCas9 negative selection 5055848
18584266 18584288 X + 27760321 HT29 viability after 19 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 -0.018751372390351184 [249,194] [311,230,217] 0 hSpCas9 negative selection 5055849
18603905 18603927 X - 27760321 HT29 viability after 16 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.739019401248616 [772,602] [1357,1275,1226] 8 hSpCas9 negative selection 5139308
18604034 18604056 X - 27760321 HT29 viability after 16 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 1.029703339765193 [315,246] [988,287,693] 9 hSpCas9 negative selection 5139309
18604435 18604457 X - 27760321 HT29 viability after 16 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 0.051552855483828236 [441,344] [440,543,379] 0 hSpCas9 negative selection 5139310
18575435 18575457 X + 27760321 HT29 viability after 16 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.2465752211655558 [393,307] [293,275,420] -3 hSpCas9 negative selection 5139311
18584266 18584288 X + 27760321 HT29 viability after 16 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.14960737353849007 [249,194] [354,305,173] 1 hSpCas9 negative selection 5139312
18603905 18603927 X - 27760321 HT29 viability after 13 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.578525271811126 [772,602] [1135,1562,894] 7 hSpCas9 negative selection 5222771
18604034 18604056 X - 27760321 HT29 viability after 13 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.7702835672179799 [315,246] [761,392,517] 8 hSpCas9 negative selection 5222772
18604435 18604457 X - 27760321 HT29 viability after 13 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 -0.07108108787979359 [441,344] [410,412,476] -1 hSpCas9 negative selection 5222773
18575435 18575457 X + 27760321 HT29 viability after 13 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 0.060652500373721 [393,307] [320,556,397] 0 hSpCas9 negative selection 5222774
18584266 18584288 X + 27760321 HT29 viability after 13 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.08261053915912397 [249,194] [326,256,237] 1 hSpCas9 negative selection 5222775
18603905 18603927 X - 27760321 HT29 viability after 10 days AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.5736169177163437 [772,602] [1640,1217,980] 7 hSpCas9 negative selection 5306234
18604034 18604056 X - 27760321 HT29 viability after 10 days ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 0.8238157914995181 [315,246] [682,645,539] 9 hSpCas9 negative selection 5306235
18604435 18604457 X - 27760321 HT29 viability after 10 days GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 -0.2744694570047873 [441,344] [410,473,336] -3 hSpCas9 negative selection 5306236
18575435 18575457 X + 27760321 HT29 viability after 10 days AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 -0.6185091745666024 [393,307] [416,198,238] -6 hSpCas9 negative selection 5306237
18584266 18584288 X + 27760321 HT29 viability after 10 days TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 0.5674231328148753 [249,194] [519,244,463] 7 hSpCas9 negative selection 5306238
18603905 18603927 X - 27760321 MOLM13 viability AGCAGTACTTTTGCCGGCTTGG CDKL5 ENSG00000008086 0.9248187031082234 [818,772] [1298,473] 6 hSpCas9 negative selection 5389697
18604034 18604056 X - 27760321 MOLM13 viability ACTAAGACTAGCTCCAGCAAGG CDKL5 ENSG00000008086 1.2203015556335852 [366,315] [243,620] 8 hSpCas9 negative selection 5389698
18604435 18604457 X - 27760321 MOLM13 viability GGCTCCGCAATTTGGGCCCTGG CDKL5 ENSG00000008086 1.150479597690142 [473,441] [447,680] 7 hSpCas9 negative selection 5389699
18575435 18575457 X + 27760321 MOLM13 viability AGGAAGCATTTCGTCGGAGGGG CDKL5 ENSG00000008086 1.0895725839797126 [491,393] [685,394] 7 hSpCas9 negative selection 5389700
18584266 18584288 X + 27760321 MOLM13 viability TTGCTCGTAATCTGTCAGAAGG CDKL5 ENSG00000008086 1.059703621751531 [342,249] [548,171] 7 hSpCas9 negative selection 5389701
18425660 18425683 X + 27661255 K562 viability GTGGGGTCCCCTGCTAGAAGTGG CDKL5 ENSG00000008086 0.1263623977647581 [2484,2405] [2288,2000] 4 dCas9-KRAB negative selection 5469968
18425663 18425686 X + 27661255 K562 viability GGGTCCCCTGCTAGAAGTGGGGG CDKL5 ENSG00000008086 0.022113879844723128 [1187,1363] [1127,950] 0 dCas9-KRAB negative selection 5469969
18425672 18425695 X + 27661255 K562 viability GCTAGAAGTGGGGGACTCGGCGG CDKL5 ENSG00000008086 -0.4282123959009472 [271,364] [213,165] -7 dCas9-KRAB negative selection 5469970
18425667 18425690 X - 27661255 K562 viability GAGTCCCCCACTTCTAGCAGGGG CDKL5 ENSG00000008086 0.12182803720646845 [897,1170] [963,835] 4 dCas9-KRAB negative selection 5469971
18426040 18426063 X - 27661255 K562 viability GGGAGCTCGTGCCGCGGGAGCGG CDKL5 ENSG00000008086 0.20495985728284555 [914,766] [853,710] 7 dCas9-KRAB negative selection 5469972
18507094 18507117 X + 27260156 BXPC3 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.17468167808016255 [1126] [1290,1176,1336,1545] 4 hSpCas9 negative selection 5534975
18507106 18507129 X - 27260156 BXPC3 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.3033366464784564 [2124] [2524,2671,2453,3400] 6 hSpCas9 negative selection 5534976
18510823 18510846 X - 27260156 BXPC3 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.30099926919138187 [1047] [1077,1418,1374,1571] 6 hSpCas9 negative selection 5534977
18564473 18564496 X + 27260156 BXPC3 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.4577794374850432 [387] [740,405,480,587] 8 hSpCas9 negative selection 5599253
18510833 18510856 X + 27260156 BXPC3 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.20079158152056586 [796] [629,762,738,777] -4 hSpCas9 negative selection 5599254
18564501 18564524 X + 27260156 BXPC3 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.2803818238051844 [418] [520,576,477,547] 6 hSpCas9 negative selection 5599255
18507094 18507117 X + 27260156 A673 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.06138489604637498 [1126] [1745,1321,1223,1394] 1 hSpCas9 negative selection 5656226
18507106 18507129 X - 27260156 A673 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.25623539656909333 [2124] [3289,2943,2940,3039] 6 hSpCas9 negative selection 5656227
18510823 18510846 X - 27260156 A673 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.018339508714897867 [1047] [1374,1189,1125,1427] 0 hSpCas9 negative selection 5656228
18564473 18564496 X + 27260156 A673 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.07866857341517847 [387] [546,447,465,514] 2 hSpCas9 negative selection 5720504
18510833 18510856 X + 27260156 A673 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.04337928371819777 [796] [964,781,936,1042] -1 hSpCas9 negative selection 5720505
18564501 18564524 X + 27260156 A673 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3065071906046599 [418] [661,568,659,600] 7 hSpCas9 negative selection 5720506
18507094 18507117 X + 27260156 A375 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.08305746578271589 [1126] [1273,1527,1350,1431] 1 hSpCas9 negative selection 5777477
18507106 18507129 X - 27260156 A375 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.4560522727629399 [2124] [3304,3879,3293,3214] 6 hSpCas9 negative selection 5777478
18510823 18510846 X - 27260156 A375 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.3604269812035017 [1047] [1255,1757,1742,1548] 5 hSpCas9 negative selection 5777479
18564473 18564496 X + 27260156 A375 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.38130316828908933 [387] [467,713,527,656] 5 hSpCas9 negative selection 5841755
18510833 18510856 X + 27260156 A375 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.0826295725447751 [796] [563,1167,1163,678] -1 hSpCas9 negative selection 5841756
18564501 18564524 X + 27260156 A375 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.07525526575649649 [418] [580,627,439,436] 1 hSpCas9 negative selection 5841757
18507094 18507117 X + 27260156 COLO741 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.3241880570707767 [1126] [1894,1491,2008] 6 hSpCas9 negative selection 5898728
18507106 18507129 X - 27260156 COLO741 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.36312898344986744 [2124] [4087,3604,2872] 7 hSpCas9 negative selection 5898729
18510823 18510846 X - 27260156 COLO741 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.10293790815976989 [1047] [1482,1578,1265] 2 hSpCas9 negative selection 5898730
18564473 18564496 X + 27260156 COLO741 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3447183724579153 [387] [584,688,610] 7 hSpCas9 negative selection 5963006
18510833 18510856 X + 27260156 COLO741 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.14973042010363125 [796] [954,925,876] -3 hSpCas9 negative selection 5963007
18564501 18564524 X + 27260156 COLO741 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.19395265969574196 [418] [590,657,586] 4 hSpCas9 negative selection 5963008
18507094 18507117 X + 27260156 CAL120 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.13732964396899927 [1126] [1686,1164,1791] 2 hSpCas9 negative selection 6019979
18507106 18507129 X - 27260156 CAL120 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5605271735471495 [2124] [4646,3520,3646] 8 hSpCas9 negative selection 6019980
18510823 18510846 X - 27260156 CAL120 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.24131806285775126 [1047] [1288,987,1060] -4 hSpCas9 negative selection 6019981
18564473 18564496 X + 27260156 CAL120 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.16726088267607378 [387] [457,745,411] 2 hSpCas9 negative selection 6084257
18510833 18510856 X + 27260156 CAL120 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.061587924513245684 [796] [882,1148,810] -1 hSpCas9 negative selection 6084258
18564501 18564524 X + 27260156 CAL120 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.46121216837975143 [418] [944,674,569] 7 hSpCas9 negative selection 6084259
18507094 18507117 X + 27260156 CADOES1 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.26792880548074693 [1126] [1270,992,1462,1322] 4 hSpCas9 negative selection 6141230
18507106 18507129 X - 27260156 CADOES1 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.36207921583427893 [2124] [2370,2369,2541,2890] 6 hSpCas9 negative selection 6141231
18510823 18510846 X - 27260156 CADOES1 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.07180313711391784 [1047] [956,942,987,1216] 1 hSpCas9 negative selection 6141232
18564473 18564496 X + 27260156 CADOES1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.1642536188253677 [387] [395,417,387,415] 3 hSpCas9 negative selection 6205508
18510833 18510856 X + 27260156 CADOES1 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.12479121614181432 [796] [640,870,1000,716] 2 hSpCas9 negative selection 6205509
18564501 18564524 X + 27260156 CADOES1 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.0984252006605052 [418] [419,379,393,476] 1 hSpCas9 negative selection 6205510
18507094 18507117 X + 27260156 EWS502 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.19657884418550498 [1126] [1080,1465,1477,1481] 3 hSpCas9 negative selection 6262481
18507106 18507129 X - 27260156 EWS502 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.41275606303785795 [2124] [2954,2839,3124,3071] 7 hSpCas9 negative selection 6262482
18510823 18510846 X - 27260156 EWS502 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.14212947202624449 [1047] [1337,1243,964,1337] 2 hSpCas9 negative selection 6262483
18564473 18564496 X + 27260156 EWS502 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.2749587797244917 [387] [495,446,436,616] 5 hSpCas9 negative selection 6326759
18510833 18510856 X + 27260156 EWS502 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.0016594033396217789 [796] [1154,533,1025,623] 0 hSpCas9 negative selection 6326760
18564501 18564524 X + 27260156 EWS502 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.4357386152510685 [418] [461,598,720,637] 7 hSpCas9 negative selection 6326761
18507094 18507117 X + 27260156 EW8 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.2655042167963888 [1126] [1249,1229,818,1153] 5 hSpCas9 negative selection 6383732
18507106 18507129 X - 27260156 EW8 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.37990700500414354 [2124] [2608,2165,2223,2001] 7 hSpCas9 negative selection 6383733
18510823 18510846 X - 27260156 EW8 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.3983180047895687 [1047] [1232,1083,1009,1177] 7 hSpCas9 negative selection 6383734
18564473 18564496 X + 27260156 EW8 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.5147363559555003 [387] [461,490,373,482] 8 hSpCas9 negative selection 6448010
18510833 18510856 X + 27260156 EW8 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.05783694898473957 [796] [536,724,608,811] 1 hSpCas9 negative selection 6448011
18564501 18564524 X + 27260156 EW8 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.4021241438221803 [418] [633,543,299,361] 7 hSpCas9 negative selection 6448012
18507094 18507117 X + 27260156 CORL105 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.3525097885564632 [1126] [1750,1269,2093,1696] 6 hSpCas9 negative selection 6504983
18507106 18507129 X - 27260156 CORL105 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.4543049570833486 [2124] [3148,3527,3684,3302] 8 hSpCas9 negative selection 6504984
18510823 18510846 X - 27260156 CORL105 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.32106595363436297 [1047] [1600,1353,1697,1508] 6 hSpCas9 negative selection 6504985
18564473 18564496 X + 27260156 CORL105 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.14536200531242208 [387] [446,541,504,512] 2 hSpCas9 negative selection 6569261
18510833 18510856 X + 27260156 CORL105 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.1445146030205544 [796] [806,769,1038,790] -3 hSpCas9 negative selection 6569262
18564501 18564524 X + 27260156 CORL105 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3242898187801786 [418] [646,565,617,627] 6 hSpCas9 negative selection 6569263
18507094 18507117 X + 27260156 HS294T viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.07706161287632596 [1126] [413,409,335,727] 1 hSpCas9 negative selection 6626234
18507106 18507129 X - 27260156 HS294T viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6794095595990517 [2124] [1371,1236,1311,1338] 8 hSpCas9 negative selection 6626235
18510823 18510846 X - 27260156 HS294T viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.010920490761409551 [1047] [397,390,377,477] 0 hSpCas9 negative selection 6626236
18564473 18564496 X + 27260156 HS294T viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.12756242068980464 [387] [135,170,218,124] 1 hSpCas9 negative selection 6690512
18510833 18510856 X + 27260156 HS294T viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.15208045248796387 [796] [478,263,276,336] 2 hSpCas9 negative selection 6690513
18564501 18564524 X + 27260156 HS294T viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.19233411156959257 [418] [188,148,165,246] 2 hSpCas9 negative selection 6690514
18507094 18507117 X + 27260156 HCC44 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.1408087652657093 [1126] [1244,1201,2086,1213] 2 hSpCas9 negative selection 6747485
18507106 18507129 X - 27260156 HCC44 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5538302256283516 [2124] [4356,2878,4200,2949] 8 hSpCas9 negative selection 6747486
18510823 18510846 X - 27260156 HCC44 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.06279985112877484 [1047] [1212,1155,1529,1106] 1 hSpCas9 negative selection 6747487
18564473 18564496 X + 27260156 HCC44 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.2564810071293853 [387] [819,473,565,281] 4 hSpCas9 negative selection 6811763
18510833 18510856 X + 27260156 HCC44 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.17248951758723152 [796] [653,1443,1038,833] 2 hSpCas9 negative selection 6811764
18564501 18564524 X + 27260156 HCC44 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3466283209617719 [418] [634,452,811,566] 5 hSpCas9 negative selection 6811765
18507094 18507117 X + 27260156 G402 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.1864099565543318 [1126] [1464,2427,1317,1100] 2 hSpCas9 negative selection 6868736
18507106 18507129 X - 27260156 G402 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5611212788465862 [2124] [3226,4303,3955,3745] 7 hSpCas9 negative selection 6868737
18510823 18510846 X - 27260156 G402 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.17728681782084932 [1047] [1486,1078,878,1122] -2 hSpCas9 negative selection 6868738
18564473 18564496 X + 27260156 G402 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3760949540884733 [387] [797,543,419,710] 5 hSpCas9 negative selection 6933014
18510833 18510856 X + 27260156 G402 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.4774712625526672 [796] [1047,759,544,501] -5 hSpCas9 negative selection 6933015
18564501 18564524 X + 27260156 G402 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.24830182558561642 [418] [765,596,391,689] 3 hSpCas9 negative selection 6933016
18507094 18507117 X + 27260156 L33 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.26411092907132727 [1126] [1319,551,920,1282] 5 hSpCas9 negative selection 6989987
18507106 18507129 X - 27260156 L33 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5074890474211635 [2124] [3155,1243,1836,2964] 8 hSpCas9 negative selection 6989988
18510823 18510846 X - 27260156 L33 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.0676864140003337 [1047] [1039,446,679,1180] 1 hSpCas9 negative selection 6989989
18564473 18564496 X + 27260156 L33 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 -0.21196510608605384 [387] [336,127,211,352] -5 hSpCas9 negative selection 7054265
18510833 18510856 X + 27260156 L33 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.28547049332418795 [796] [646,271,440,603] -6 hSpCas9 negative selection 7054266
18564501 18564524 X + 27260156 L33 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3996667010828338 [418] [656,222,272,571] 8 hSpCas9 negative selection 7054267
18507094 18507117 X + 27260156 K562 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.21536558019873442 [1126] [1502,1366,1029,818] 2 hSpCas9 negative selection 7111238
18507106 18507129 X - 27260156 K562 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6657997727370204 [2124] [3243,3060,3442,2310] 8 hSpCas9 negative selection 7111239
18510823 18510846 X - 27260156 K562 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.2818511704689788 [1047] [1053,1084,1180,1182] 3 hSpCas9 negative selection 7111240
18564473 18564496 X + 27260156 K562 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.22446218693892647 [387] [379,459,350,415] 3 hSpCas9 negative selection 7175516
18510833 18510856 X + 27260156 K562 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.38004235300586847 [796] [827,409,397,550] -5 hSpCas9 negative selection 7175517
18564501 18564524 X + 27260156 K562 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.2565642316720707 [418] [443,578,531,249] 3 hSpCas9 negative selection 7175518
18507094 18507117 X + 27260156 HT29 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.16541796819803167 [1126] [1581,1796,1438,1363] 3 hSpCas9 negative selection 7232489
18507106 18507129 X - 27260156 HT29 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.42247909839472486 [2124] [3922,3674,3286,3043] 7 hSpCas9 negative selection 7232490
18510823 18510846 X - 27260156 HT29 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.09893455823825104 [1047] [1438,1323,1547,1163] 2 hSpCas9 negative selection 7232491
18564473 18564496 X + 27260156 HT29 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.15124855792783012 [387] [659,490,531,427] 3 hSpCas9 negative selection 7296767
18510833 18510856 X + 27260156 HT29 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.1884257980050481 [796] [815,863,869,843] -4 hSpCas9 negative selection 7296768
18564501 18564524 X + 27260156 HT29 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.09469738977515009 [418] [658,499,655,381] 1 hSpCas9 negative selection 7296769
18507094 18507117 X + 27260156 MHHES1 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.4174921349977063 [1126] [1891,1997,1648,1340] 7 hSpCas9 negative selection 7353740
18507106 18507129 X - 27260156 MHHES1 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.4301253790557076 [2124] [3575,3700,3481,2361] 7 hSpCas9 negative selection 7353741
18510823 18510846 X - 27260156 MHHES1 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.45156254967461695 [1047] [2037,1733,1321,1429] 7 hSpCas9 negative selection 7353742
18564473 18564496 X + 27260156 MHHES1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.41044006313600345 [387] [839,764,469,340] 7 hSpCas9 negative selection 7418018
18510833 18510856 X + 27260156 MHHES1 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.26423560380791933 [796] [1121,1148,1269,820] 5 hSpCas9 negative selection 7418019
18564501 18564524 X + 27260156 MHHES1 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.4365843904635657 [418] [598,686,565,677] 7 hSpCas9 negative selection 7418020
18507094 18507117 X + 27260156 MEWO viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.12845913239694529 [1126] [1368,1024,1105] 3 hSpCas9 negative selection 7474991
18507106 18507129 X - 27260156 MEWO viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.3763704636002507 [2124] [2842,2420,2528] 7 hSpCas9 negative selection 7474992
18510823 18510846 X - 27260156 MEWO viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.22462220899770413 [1047] [1338,971,1163] 5 hSpCas9 negative selection 7474993
18564473 18564496 X + 27260156 MEWO viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.1423193593861984 [387] [390,388,419] 3 hSpCas9 negative selection 7539269
18510833 18510856 X + 27260156 MEWO viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.22886737853638817 [796] [561,687,643] -5 hSpCas9 negative selection 7539270
18564501 18564524 X + 27260156 MEWO viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3194313465169405 [418] [643,355,497] 6 hSpCas9 negative selection 7539271
18507094 18507117 X + 27260156 LNCAPCLONEFGC viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.15538484957065823 [1126] [1047,1100,1390,1048] 2 hSpCas9 negative selection 7596242
18507106 18507129 X - 27260156 LNCAPCLONEFGC viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5723973261057673 [2124] [3194,2489,2951,2841] 8 hSpCas9 negative selection 7596243
18510823 18510846 X - 27260156 LNCAPCLONEFGC viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.09758713166075217 [1047] [885,1129,1046,998] 1 hSpCas9 negative selection 7596244
18564473 18564496 X + 27260156 LNCAPCLONEFGC viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.7526234801600136 [387] [686,400,705,601] 9 hSpCas9 negative selection 7660520
18510833 18510856 X + 27260156 LNCAPCLONEFGC viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.12176603178858669 [796] [528,552,955,668] -2 hSpCas9 negative selection 7660521
18564501 18564524 X + 27260156 LNCAPCLONEFGC viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.435509500485352 [418] [482,411,518,646] 6 hSpCas9 negative selection 7660522
18507094 18507117 X + 27260156 PANC0327 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.4079767507606309 [1126] [1215,1880,1055,1078] 6 hSpCas9 negative selection 7717493
18507106 18507129 X - 27260156 PANC0327 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5489347858170168 [2124] [2087,2670,2869,3372] 7 hSpCas9 negative selection 7717494
18510823 18510846 X - 27260156 PANC0327 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.4567027216274737 [1047] [1159,1203,1328,1416] 6 hSpCas9 negative selection 7717495
18564473 18564496 X + 27260156 PANC0327 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.4265069671598163 [387] [318,608,414,478] 6 hSpCas9 negative selection 7781771
18510833 18510856 X + 27260156 PANC0327 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.028541660857825946 [796] [782,635,986,498] 0 hSpCas9 negative selection 7781772
18564501 18564524 X + 27260156 PANC0327 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.28289163248960325 [418] [578,454,311,474] 4 hSpCas9 negative selection 7781773
18507094 18507117 X + 27260156 NCIH2009 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.006126016538608781 [1126] [1840,1114,1844] 0 hSpCas9 negative selection 7838744
18507106 18507129 X - 27260156 NCIH2009 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6029373694771571 [2124] [5253,3922,4500] 8 hSpCas9 negative selection 7838745
18510823 18510846 X - 27260156 NCIH2009 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.28783885535147413 [1047] [2148,1512,1773] 4 hSpCas9 negative selection 7838746
18564473 18564496 X + 27260156 NCIH2009 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.08768769767107418 [387] [666,586,490] 1 hSpCas9 negative selection 7903022
18510833 18510856 X + 27260156 NCIH2009 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.24311110324408547 [796] [1192,818,860] -3 hSpCas9 negative selection 7903023
18564501 18564524 X + 27260156 NCIH2009 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3488028706997515 [418] [898,614,753] 5 hSpCas9 negative selection 7903024
18507094 18507117 X + 27260156 NCIH1373 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.3291731651199905 [1126] [1988,1196,1284,526] 3 hSpCas9 negative selection 7959995
18507106 18507129 X - 27260156 NCIH1373 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 1.1668371644290558 [2124] [5547,4694,4431,1813] 9 hSpCas9 negative selection 7959996
18510823 18510846 X - 27260156 NCIH1373 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.6320309232169585 [1047] [2139,1227,2201,474] 6 hSpCas9 negative selection 7959997
18564473 18564496 X + 27260156 NCIH1373 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.17206804353807698 [387] [670,413,275,169] 1 hSpCas9 negative selection 8024273
18510833 18510856 X + 27260156 NCIH1373 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.05857201742927054 [796] [1279,562,951,188] 0 hSpCas9 negative selection 8024274
18564501 18564524 X + 27260156 NCIH1373 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.2944933545504179 [418] [448,640,618,147] 3 hSpCas9 negative selection 8024275
18507094 18507117 X + 27260156 PATU8902 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.4826315029095576 [1126] [1923,2157,2187,2529] 5 hSpCas9 negative selection 8081246
18507106 18507129 X - 27260156 PATU8902 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6281936708396092 [2124] [6132,4840,2877,4863] 6 hSpCas9 negative selection 8081247
18510823 18510846 X - 27260156 PATU8902 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.14786016948421987 [1047] [1462,1762,1675,1529] 1 hSpCas9 negative selection 8081248
18564473 18564496 X + 27260156 PATU8902 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.32683299834603863 [387] [652,602,650,822] 3 hSpCas9 negative selection 8145524
18510833 18510856 X + 27260156 PATU8902 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.2579669411846771 [796] [1184,1049,1364,1738] 2 hSpCas9 negative selection 8145525
18564501 18564524 X + 27260156 PATU8902 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.5607565400096514 [418] [1028,626,576,1329] 6 hSpCas9 negative selection 8145526
18507094 18507117 X + 27260156 PANC1 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.39026784866935293 [1126] [1256,1532,1152,1178] 6 hSpCas9 negative selection 8202497
18507106 18507129 X - 27260156 PANC1 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6067107062066506 [2124] [2678,3813,2826,2082] 8 hSpCas9 negative selection 8202498
18510823 18510846 X - 27260156 PANC1 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.46026236809922905 [1047] [1082,1741,1248,1004] 7 hSpCas9 negative selection 8202499
18564473 18564496 X + 27260156 PANC1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3225394748255945 [387] [412,380,574,303] 5 hSpCas9 negative selection 8266775
18510833 18510856 X + 27260156 PANC1 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.2392838943105544 [796] [748,613,563,413] -4 hSpCas9 negative selection 8266776
18564501 18564524 X + 27260156 PANC1 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.5865689039332246 [418] [636,597,431,500] 8 hSpCas9 negative selection 8266777
18507094 18507117 X + 27260156 PANC0813 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.30693777160997193 [1126] [1290,1575,1879,1762] 5 hSpCas9 negative selection 8323748
18507106 18507129 X - 27260156 PANC0813 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.5703066368401353 [2124] [3537,4061,3541,3662] 8 hSpCas9 negative selection 8323749
18510823 18510846 X - 27260156 PANC0813 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.2504200651350452 [1047] [1526,1465,1050,1795] 4 hSpCas9 negative selection 8323750
18564473 18564496 X + 27260156 PANC0813 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.2675106642789144 [387] [500,462,628,593] 4 hSpCas9 negative selection 8388026
18510833 18510856 X + 27260156 PANC0813 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.31770067777628286 [796] [915,975,482,647] -5 hSpCas9 negative selection 8388027
18564501 18564524 X + 27260156 PANC0813 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.5381535812169338 [418] [748,575,866,671] 8 hSpCas9 negative selection 8388028
18507094 18507117 X + 27260156 RDES viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.16640553276355563 [1126] [984,1347,1649,1997] 2 hSpCas9 negative selection 8444999
18507106 18507129 X - 27260156 RDES viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.4588930900147896 [2124] [2566,3372,3653,4024] 7 hSpCas9 negative selection 8445000
18510823 18510846 X - 27260156 RDES viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.11752497726720912 [1047] [1068,1104,1342,1825] 2 hSpCas9 negative selection 8445001
18564473 18564496 X + 27260156 RDES viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.33956312969561286 [387] [442,517,663,666] 5 hSpCas9 negative selection 8509277
18510833 18510856 X + 27260156 RDES viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.22441862808103907 [796] [697,711,796,958] -4 hSpCas9 negative selection 8509278
18564501 18564524 X + 27260156 RDES viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.20735175160126168 [418] [482,482,552,739] 3 hSpCas9 negative selection 8509279
18507094 18507117 X + 27260156 PC3 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.2243217762907963 [1126] [747,1524,2349,1138] 5 hSpCas9 negative selection 8566250
18507106 18507129 X - 27260156 PC3 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.34111180196277013 [2124] [1797,2325,4575,2912] 7 hSpCas9 negative selection 8566251
18510823 18510846 X - 27260156 PC3 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.19328907975967824 [1047] [786,1064,2086,1253] 4 hSpCas9 negative selection 8566252
18564473 18564496 X + 27260156 PC3 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.14763490567527598 [387] [319,363,681,449] 3 hSpCas9 negative selection 8630528
18510833 18510856 X + 27260156 PC3 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.43796303874758347 [796] [459,517,701,704] -7 hSpCas9 negative selection 8630529
18564501 18564524 X + 27260156 PC3 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3877342348638212 [418] [288,426,1097,666] 7 hSpCas9 negative selection 8630530
18507094 18507117 X + 27260156 PATU8988T viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.22791951572406455 [1126] [979,1437,1103,1624] 4 hSpCas9 negative selection 8687501
18507106 18507129 X - 27260156 PATU8988T viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.43667733356617644 [2124] [2638,3326,2207,3020] 7 hSpCas9 negative selection 8687502
18510823 18510846 X - 27260156 PATU8988T viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.04309765929685394 [1047] [1132,942,1053,1032] 0 hSpCas9 negative selection 8687503
18564473 18564496 X + 27260156 PATU8988T viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.6000845591927007 [387] [824,470,473,488] 8 hSpCas9 negative selection 8751779
18510833 18510856 X + 27260156 PATU8988T viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.43720003205850844 [796] [663,602,512,492] -6 hSpCas9 negative selection 8751780
18564501 18564524 X + 27260156 PATU8988T viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.39564394650293155 [418] [408,462,465,808] 6 hSpCas9 negative selection 8751781
18507094 18507117 X + 27260156 T47D viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.27275031961155105 [1126] [1702,1428,1547,1681] 6 hSpCas9 negative selection 8808752
18507106 18507129 X - 27260156 T47D viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.40814680640402834 [2124] [3387,2972,3437,3367] 8 hSpCas9 negative selection 8808753
18510823 18510846 X - 27260156 T47D viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.22306521704332116 [1047] [1589,1260,1326,1541] 5 hSpCas9 negative selection 8808754
18564473 18564496 X + 27260156 T47D viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3220754768658575 [387] [511,545,604,598] 6 hSpCas9 negative selection 8873030
18510833 18510856 X + 27260156 T47D viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.032079307033444415 [796] [791,920,820,1103] 0 hSpCas9 negative selection 8873031
18564501 18564524 X + 27260156 T47D viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.2260740621550689 [418] [607,498,516,669] 5 hSpCas9 negative selection 8873032
18507094 18507117 X + 27260156 SU8686 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.20792127244876224 [1126] [1055,1218,1397,1562] 3 hSpCas9 negative selection 8930003
18507106 18507129 X - 27260156 SU8686 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.6223928508520897 [2124] [3064,2593,3535,3987] 9 hSpCas9 negative selection 8930004
18510823 18510846 X - 27260156 SU8686 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.20437882892307435 [1047] [1137,932,1643,1102] 3 hSpCas9 negative selection 8930005
18564473 18564496 X + 27260156 SU8686 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.13844876374298945 [387] [349,334,361,707] 2 hSpCas9 negative selection 8994281
18510833 18510856 X + 27260156 SU8686 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.037930196049549614 [796] [652,666,844,1169] 0 hSpCas9 negative selection 8994282
18564501 18564524 X + 27260156 SU8686 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.17018030270877332 [418] [436,380,434,657] 3 hSpCas9 negative selection 8994283
18507094 18507117 X + 27260156 SKES1 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.20298817064749564 [1126] [1384,1363,1344,1110] 4 hSpCas9 negative selection 9051254
18507106 18507129 X - 27260156 SKES1 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.2847433792335119 [2124] [2651,2990,2511,2246] 6 hSpCas9 negative selection 9051255
18510823 18510846 X - 27260156 SKES1 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.18375483684423388 [1047] [1357,1164,1227,1025] 4 hSpCas9 negative selection 9051256
18564473 18564496 X + 27260156 SKES1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.21685098964421612 [387] [420,590,410,391] 4 hSpCas9 negative selection 9115532
18510833 18510856 X + 27260156 SKES1 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.04430389505148502 [796] [884,846,807,582] -1 hSpCas9 negative selection 9115533
18564501 18564524 X + 27260156 SKES1 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3936298966186531 [418] [884,477,541,347] 7 hSpCas9 negative selection 9115534
18507094 18507117 X + 27260156 TOV112D viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.10582381604479885 [1126] [1290,1624,1013,1038] 2 hSpCas9 negative selection 9172505
18507106 18507129 X - 27260156 TOV112D viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.19328134245678852 [2124] [2581,3142,1948,2247] 4 hSpCas9 negative selection 9172506
18510823 18510846 X - 27260156 TOV112D viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 -0.0270530817283674 [1047] [821,1248,1302,787] 0 hSpCas9 negative selection 9172507
18564473 18564496 X + 27260156 TOV112D viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.22750402024482153 [387] [712,428,400,295] 4 hSpCas9 negative selection 9236783
18510833 18510856 X + 27260156 TOV112D viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 0.03731416189132297 [796] [773,676,1130,658] 0 hSpCas9 negative selection 9236784
18564501 18564524 X + 27260156 TOV112D viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.3740486516528242 [418] [622,691,479,425] 7 hSpCas9 negative selection 9236785
18507094 18507117 X + 27260156 TC71 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.2010993555706031 [1126] [1352,1388,1260,1567] 5 hSpCas9 negative selection 9293756
18507106 18507129 X - 27260156 TC71 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.37757713494774947 [2124] [3007,2774,3045,3006] 8 hSpCas9 negative selection 9293757
18510823 18510846 X - 27260156 TC71 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.1552825861459699 [1047] [1086,1378,1224,1321] 4 hSpCas9 negative selection 9293758
18564473 18564496 X + 27260156 TC71 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.10620400395956686 [387] [496,413,392,489] 2 hSpCas9 negative selection 9358034
18510833 18510856 X + 27260156 TC71 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.12469895362321681 [796] [812,837,714,768] -3 hSpCas9 negative selection 9358035
18564501 18564524 X + 27260156 TC71 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.12057010196872951 [418] [480,417,511,544] 3 hSpCas9 negative selection 9358036
18507094 18507117 X + 27260156 TC32 viability TTCATGAAGATTCCTAACATTGG CDKL5 ENSG00000008086 0.29477502752900975 [1126] [1058,1041,1819,1423] 5 hSpCas9 negative selection 9415007
18507106 18507129 X - 27260156 TC32 viability TTCATCACATTACCAATGTTAGG CDKL5 ENSG00000008086 0.22691914629646792 [2124] [2122,1642,3389,2540] 4 hSpCas9 negative selection 9415008
18510823 18510846 X - 27260156 TC32 viability GCATTTAAGTACAACTCCATAGG CDKL5 ENSG00000008086 0.1499614401354683 [1047] [955,1045,1048,1287] 2 hSpCas9 negative selection 9415009
18564473 18564496 X + 27260156 TC32 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.14081833855732168 [387] [428,184,532,548] 2 hSpCas9 negative selection 9479285
18510833 18510856 X + 27260156 TC32 viability TGTACTTAAATGCAGACACAAGG CDKL5 ENSG00000008086 -0.46067594674018236 [796] [538,388,743,567] -7 hSpCas9 negative selection 9479286
18564501 18564524 X + 27260156 TC32 viability AAGAAATTCAAGGACAGTGAAGG CDKL5 ENSG00000008086 0.23237443458657608 [418] [360,293,639,647] 4 hSpCas9 negative selection 9479287
18575433 18575456 X + 27869803 HPAFII viability after 27 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.8272299290432346 [45] [37,46,NaN] 6 hSpCas9 negative selection 9608373
18584305 18584328 X + 27869803 HPAFII viability after 27 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.7116678047556704 [275] [331,158,NaN] 6 hSpCas9 negative selection 9608374
18588131 18588154 X - 27869803 HPAFII viability after 27 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.9350132118822203 [87] [153,195,NaN] 9 hSpCas9 negative selection 9608375
18595362 18595385 X - 27869803 HPAFII viability after 27 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.0513158227979482 [133] [229,75,NaN] 8 hSpCas9 negative selection 9608376
18598480 18598503 X - 27869803 HPAFII viability after 27 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.8180725606361398 [147] [242,48,NaN] 6 hSpCas9 negative selection 9608377
18604634 18604657 X + 27869803 HPAFII viability after 27 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.4123131775917871 [134] [112,78,NaN] 3 hSpCas9 negative selection 9608378
18575433 18575456 X + 27869803 HPAFII viability after 15 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.08496037972273 [45] [168,64,NaN] 9 hSpCas9 negative selection 9690822
18584305 18584328 X + 27869803 HPAFII viability after 15 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.3293025078409484 [275] [532,272,NaN] 4 hSpCas9 negative selection 9690823
18588131 18588154 X - 27869803 HPAFII viability after 15 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.0317428293499584 [87] [127,233,NaN] 9 hSpCas9 negative selection 9690824
18595362 18595385 X - 27869803 HPAFII viability after 15 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.5838324362500413 [133] [406,96,NaN] 6 hSpCas9 negative selection 9690825
18598480 18598503 X - 27869803 HPAFII viability after 15 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.4913646878030193 [147] [423,98,NaN] 5 hSpCas9 negative selection 9690826
18604634 18604657 X + 27869803 HPAFII viability after 15 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.6890082984055687 [134] [318,180,NaN] 7 hSpCas9 negative selection 9690827
18575433 18575456 X + 27869803 ASPC1 viability after 36 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 -0.4207053659073887 [231] [41,150,0] -4 hSpCas9 negative selection 9773271
18584305 18584328 X + 27869803 ASPC1 viability after 36 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.5568156966985273 [556] [358,184,311] 5 hSpCas9 negative selection 9773272
18588131 18588154 X - 27869803 ASPC1 viability after 36 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 0.5805254468954165 [341] [140,146,227] 6 hSpCas9 negative selection 9773273
18595362 18595385 X - 27869803 ASPC1 viability after 36 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.7894600867005086 [252] [230,153,94] 7 hSpCas9 negative selection 9773274
18598480 18598503 X - 27869803 ASPC1 viability after 36 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.2667610363910907 [273] [43,280,31] 2 hSpCas9 negative selection 9773275
18604634 18604657 X + 27869803 ASPC1 viability after 36 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.22973060134882417 [389] [144,102,104] -2 hSpCas9 negative selection 9773276
18575433 18575456 X + 27869803 PATU8988S viability after 35 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.8086414588076456 [89] [58,67,NaN] 8 hSpCas9 negative selection 9855720
18584305 18584328 X + 27869803 PATU8988S viability after 35 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.23259746831808073 [571] [347,192,NaN] 2 hSpCas9 negative selection 9855721
18588131 18588154 X - 27869803 PATU8988S viability after 35 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -1.442477995776366 [279] [37,44,NaN] -8 hSpCas9 negative selection 9855722
18595362 18595385 X - 27869803 PATU8988S viability after 35 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.6200332202936716 [231] [189,96,NaN] 6 hSpCas9 negative selection 9855723
18598480 18598503 X - 27869803 PATU8988S viability after 35 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 1.1253934401016887 [355] [223,401,NaN] 9 hSpCas9 negative selection 9855724
18604634 18604657 X + 27869803 PATU8988S viability after 35 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.08742228809218122 [327] [51,196,NaN] -1 hSpCas9 negative selection 9855725
18575433 18575456 X + 27869803 PATU8988S viability after 31 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 0.7681374900026645 [89] [50,73,NaN] 8 hSpCas9 negative selection 9938169
18584305 18584328 X + 27869803 PATU8988S viability after 31 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.3111038125552129 [571] [333,217,NaN] 4 hSpCas9 negative selection 9938170
18588131 18588154 X - 27869803 PATU8988S viability after 31 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 -0.7044256026123105 [279] [53,86,NaN] -6 hSpCas9 negative selection 9938171
18595362 18595385 X - 27869803 PATU8988S viability after 31 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 0.6499962641105131 [231] [149,138,NaN] 7 hSpCas9 negative selection 9938172
18598480 18598503 X - 27869803 PATU8988S viability after 31 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.5830146523622799 [355] [220,201,NaN] 7 hSpCas9 negative selection 9938173
18604634 18604657 X + 27869803 PATU8988S viability after 31 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 -0.24402625982879744 [327] [87,138,NaN] -3 hSpCas9 negative selection 9938174
18575433 18575456 X + 27869803 HPAFII viability after 35 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.1707613137411024 [45] [82,17,NaN] 7 hSpCas9 negative selection 10020618
18584305 18584328 X + 27869803 HPAFII viability after 35 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.6542238058459178 [275] [241,194,NaN] 4 hSpCas9 negative selection 10020619
18588131 18588154 X - 27869803 HPAFII viability after 35 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.8353246905023903 [87] [110,212,NaN] 9 hSpCas9 negative selection 10020620
18595362 18595385 X - 27869803 HPAFII viability after 35 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.3907072871911077 [133] [278,63,NaN] 8 hSpCas9 negative selection 10020621
18598480 18598503 X - 27869803 HPAFII viability after 35 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.6771954415487496 [147] [203,24,NaN] 4 hSpCas9 negative selection 10020622
18604634 18604657 X + 27869803 HPAFII viability after 35 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.5405501608317858 [134] [89,109,NaN] 3 hSpCas9 negative selection 10020623
18575433 18575456 X + 27869803 HPAFII viability after 31 days GAAGGAAGCATTTCGTCGGAGGG CDKL5 ENSG00000008086 1.7343954698693458 [45] [105,63,NaN] 9 hSpCas9 negative selection 10103067
18584305 18584328 X + 27869803 HPAFII viability after 31 days CAGAGTACGTTGCCACCAGATGG CDKL5 ENSG00000008086 0.9244139312013981 [275] [259,330,NaN] 7 hSpCas9 negative selection 10103068
18588131 18588154 X - 27869803 HPAFII viability after 31 days AACCTCTTACCCGGAGCCCATGG CDKL5 ENSG00000008086 1.990330888095128 [87] [111,287,NaN] 9 hSpCas9 negative selection 10103069
18595362 18595385 X - 27869803 HPAFII viability after 31 days TTCTTTCCAAGGACTGAGGATGG CDKL5 ENSG00000008086 1.961018557633719 [133] [410,163,NaN] 9 hSpCas9 negative selection 10103070
18598480 18598503 X - 27869803 HPAFII viability after 31 days TCTGTCAAGTATCTGTCAGCTGG CDKL5 ENSG00000008086 0.790547210482927 [147] [247,29,NaN] 6 hSpCas9 negative selection 10103071
18604634 18604657 X + 27869803 HPAFII viability after 31 days ATTGAAGCTGCCGGAGCACATGG CDKL5 ENSG00000008086 0.3253260698429973 [134] [70,120,NaN] 2 hSpCas9 negative selection 10103072
18587997 18588020 X + 28162770 P31FUJ viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.4573185262921602 [312] [504] 5 hSpCas9 negative selection 10130860
18603957 18603980 X + 28162770 P31FUJ viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.10319300260853381 [346] [437] 1 hSpCas9 negative selection 10130861
18604371 18604394 X + 28162770 P31FUJ viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 1.0302322014194154 [49] [119] 9 hSpCas9 negative selection 10130862
18604804 18604827 X + 28162770 P31FUJ viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.6689337792707555 [242] [453] 7 hSpCas9 negative selection 10130863
18609549 18609572 X + 28162770 P31FUJ viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.2255627265285658 [122] [168] 2 hSpCas9 negative selection 10130864
18613154 18613177 X - 28162770 P31FUJ viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.36057253612297757 [341] [515] 4 hSpCas9 negative selection 10130865
18625192 18625215 X + 28162770 P31FUJ viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 1.087275094785042 [311] [778] 9 hSpCas9 negative selection 10130866
18628526 18628549 X + 28162770 P31FUJ viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.02844370590819234 [137] [158] 0 hSpCas9 negative selection 10130867
18564473 18564496 X + 28162770 P31FUJ viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.4827539994928407 [963] [1582] 5 hSpCas9 negative selection 10130868
18584317 18584340 X - 28162770 P31FUJ viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5311725100848067 [380] [646] 6 hSpCas9 negative selection 10130869
18587997 18588020 X + 28162770 TF1 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 NaN [NaN] [496] 1 hSpCas9 negative selection 10300226
18603957 18603980 X + 28162770 TF1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 NaN [NaN] [463] 1 hSpCas9 negative selection 10300227
18604371 18604394 X + 28162770 TF1 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 NaN [NaN] [126] 1 hSpCas9 negative selection 10300228
18604804 18604827 X + 28162770 TF1 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 NaN [NaN] [532] 1 hSpCas9 negative selection 10300229
18609549 18609572 X + 28162770 TF1 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 NaN [NaN] [73] 1 hSpCas9 negative selection 10300230
18613154 18613177 X - 28162770 TF1 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 NaN [NaN] [584] 1 hSpCas9 negative selection 10300231
18625192 18625215 X + 28162770 TF1 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 NaN [NaN] [490] 1 hSpCas9 negative selection 10300232
18628526 18628549 X + 28162770 TF1 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 NaN [NaN] [97] 1 hSpCas9 negative selection 10300233
18564473 18564496 X + 28162770 TF1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 NaN [NaN] [1186] 1 hSpCas9 negative selection 10300234
18584317 18584340 X - 28162770 TF1 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 NaN [NaN] [446] 1 hSpCas9 negative selection 10300235
18587997 18588020 X + 28162770 SKM1 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.21547300739665726 [75] [155] 2 hSpCas9 negative selection 10469592
18603957 18603980 X + 28162770 SKM1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.30280475771427506 [82] [180] 3 hSpCas9 negative selection 10469593
18604371 18604394 X + 28162770 SKM1 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 -0.2914869813232257 [17] [25] -2 hSpCas9 negative selection 10469594
18604804 18604827 X + 28162770 SKM1 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 1.0625210845580586 [90] [335] 8 hSpCas9 negative selection 10469595
18609549 18609572 X + 28162770 SKM1 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.5190352198130613 [59] [151] 5 hSpCas9 negative selection 10469596
18613154 18613177 X - 28162770 SKM1 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.5405683813627027 [104] [269] 5 hSpCas9 negative selection 10469597
18625192 18625215 X + 28162770 SKM1 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 -0.2480103151218524 [87] [130] -2 hSpCas9 negative selection 10469598
18628526 18628549 X + 28162770 SKM1 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.2814333166593026 [21] [31] -2 hSpCas9 negative selection 10469599
18564473 18564496 X + 28162770 SKM1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.7048578481355823 [227] [656] 6 hSpCas9 negative selection 10469600
18584317 18584340 X - 28162770 SKM1 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.4146045825341431 [100] [237] 4 hSpCas9 negative selection 10469601
18587997 18588020 X + 28162770 SKM1 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.21547300739665726 [75] [155] 2 hSpCas9 negative selection 10638958
18603957 18603980 X + 28162770 SKM1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.30280475771427506 [82] [180] 3 hSpCas9 negative selection 10638959
18604371 18604394 X + 28162770 SKM1 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 -0.2914869813232257 [17] [25] -2 hSpCas9 negative selection 10638960
18604804 18604827 X + 28162770 SKM1 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 1.0625210845580586 [90] [335] 8 hSpCas9 negative selection 10638961
18609549 18609572 X + 28162770 SKM1 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.5190352198130613 [59] [151] 5 hSpCas9 negative selection 10638962
18613154 18613177 X - 28162770 SKM1 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.5405683813627027 [104] [269] 5 hSpCas9 negative selection 10638963
18625192 18625215 X + 28162770 SKM1 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 -0.2480103151218524 [87] [130] -2 hSpCas9 negative selection 10638964
18628526 18628549 X + 28162770 SKM1 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.2814333166593026 [21] [31] -2 hSpCas9 negative selection 10638965
18564473 18564496 X + 28162770 SKM1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.7048578481355823 [227] [656] 6 hSpCas9 negative selection 10638966
18584317 18584340 X - 28162770 SKM1 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.4146045825341431 [100] [237] 4 hSpCas9 negative selection 10638967
18587997 18588020 X + 28162770 PL21 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 -0.6236097458189527 [353] [99] -4 hSpCas9 negative selection 10808324
18603957 18603980 X + 28162770 PL21 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.08576925759706022 [355] [145] 0 hSpCas9 negative selection 10808325
18604371 18604394 X + 28162770 PL21 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 1.0015939351072398 [69] [60] 8 hSpCas9 negative selection 10808326
18604804 18604827 X + 28162770 PL21 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.7867424735917318 [292] [219] 6 hSpCas9 negative selection 10808327
18609549 18609572 X + 28162770 PL21 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.45647936774910564 [143] [85] 4 hSpCas9 negative selection 10808328
18613154 18613177 X - 28162770 PL21 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.09409797707899559 [380] [176] 0 hSpCas9 negative selection 10808329
18625192 18625215 X + 28162770 PL21 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.509243669019099 [225] [139] 4 hSpCas9 negative selection 10808330
18628526 18628549 X + 28162770 PL21 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.11180439182542012 [71] [28] -1 hSpCas9 negative selection 10808331
18564473 18564496 X + 28162770 PL21 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.008029760088914761 [769] [336] 0 hSpCas9 negative selection 10808332
18584317 18584340 X - 28162770 PL21 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5307267919688525 [298] [187] 4 hSpCas9 negative selection 10808333
18587997 18588020 X + 28162770 P31FUJ viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.4573185262921602 [312] [504] 5 hSpCas9 negative selection 10977690
18603957 18603980 X + 28162770 P31FUJ viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.10319300260853381 [346] [437] 1 hSpCas9 negative selection 10977691
18604371 18604394 X + 28162770 P31FUJ viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 1.0302322014194154 [49] [119] 9 hSpCas9 negative selection 10977692
18604804 18604827 X + 28162770 P31FUJ viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.6689337792707555 [242] [453] 7 hSpCas9 negative selection 10977693
18609549 18609572 X + 28162770 P31FUJ viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.2255627265285658 [122] [168] 2 hSpCas9 negative selection 10977694
18613154 18613177 X - 28162770 P31FUJ viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.36057253612297757 [341] [515] 4 hSpCas9 negative selection 10977695
18625192 18625215 X + 28162770 P31FUJ viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 1.087275094785042 [311] [778] 9 hSpCas9 negative selection 10977696
18628526 18628549 X + 28162770 P31FUJ viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.02844370590819234 [137] [158] 0 hSpCas9 negative selection 10977697
18564473 18564496 X + 28162770 P31FUJ viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.4827539994928407 [963] [1582] 5 hSpCas9 negative selection 10977698
18584317 18584340 X - 28162770 P31FUJ viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5311725100848067 [380] [646] 6 hSpCas9 negative selection 10977699
18587997 18588020 X + 28162770 OCIAML5 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.9013760688443135 [147] [498] 7 hSpCas9 negative selection 11147056
18603957 18603980 X + 28162770 OCIAML5 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.08813392909752138 [264] [449] 0 hSpCas9 negative selection 11147057
18604371 18604394 X + 28162770 OCIAML5 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.3615289022352919 [46] [108] 3 hSpCas9 negative selection 11147058
18604804 18604827 X + 28162770 OCIAML5 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.332851145053788 [233] [531] 3 hSpCas9 negative selection 11147059
18609549 18609572 X + 28162770 OCIAML5 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 1.268685588596613 [62] [273] 9 hSpCas9 negative selection 11147060
18613154 18613177 X - 28162770 OCIAML5 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 -0.053053628597173996 [222] [387] 0 hSpCas9 negative selection 11147061
18625192 18625215 X + 28162770 OCIAML5 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.6081597021811022 [164] [453] 5 hSpCas9 negative selection 11147062
18628526 18628549 X + 28162770 OCIAML5 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 1.910434115409347 [41] [284] 9 hSpCas9 negative selection 11147063
18564473 18564496 X + 28162770 OCIAML5 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.8172244487064311 [514] [1637] 7 hSpCas9 negative selection 11147064
18584317 18584340 X - 28162770 OCIAML5 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.33470194074172954 [245] [559] 3 hSpCas9 negative selection 11147065
18587997 18588020 X + 28162770 EOL1 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 1.0217874251067423 [544] [582] 8 hSpCas9 negative selection 11316422
18603957 18603980 X + 28162770 EOL1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.828192707675399 [355] [332] 7 hSpCas9 negative selection 11316423
18604371 18604394 X + 28162770 EOL1 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 1.0892925339071668 [123] [138] 8 hSpCas9 negative selection 11316424
18604804 18604827 X + 28162770 EOL1 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.508553895033672 [502] [376] 4 hSpCas9 negative selection 11316425
18609549 18609572 X + 28162770 EOL1 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 -0.3815553561551454 [271] [109] -3 hSpCas9 negative selection 11316426
18613154 18613177 X - 28162770 EOL1 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.7880270101480363 [586] [533] 7 hSpCas9 negative selection 11316427
18625192 18625215 X + 28162770 EOL1 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.7783771234276395 [383] [346] 7 hSpCas9 negative selection 11316428
18628526 18628549 X + 28162770 EOL1 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.03481024393211962 [104] [53] 0 hSpCas9 negative selection 11316429
18564473 18564496 X + 28162770 EOL1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3453908925305842 [991] [663] 3 hSpCas9 negative selection 11316430
18584317 18584340 X - 28162770 EOL1 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.3904576006479274 [403] [278] 3 hSpCas9 negative selection 11316431
18587997 18588020 X + 28162770 MOLM13 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.3092644125346863 [460] [412] 2 hSpCas9 negative selection 11485788
18603957 18603980 X + 28162770 MOLM13 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.9175730236303139 [431] [589] 7 hSpCas9 negative selection 11485789
18604371 18604394 X + 28162770 MOLM13 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.6475954037794768 [97] [110] 5 hSpCas9 negative selection 11485790
18604804 18604827 X + 28162770 MOLM13 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 1.4411720431687995 [435] [855] 9 hSpCas9 negative selection 11485791
18609549 18609572 X + 28162770 MOLM13 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.4617891820081609 [236] [235] 3 hSpCas9 negative selection 11485792
18613154 18613177 X - 28162770 MOLM13 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 1.1894629252938032 [489] [807] 8 hSpCas9 negative selection 11485793
18625192 18625215 X + 28162770 MOLM13 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.02965103882386888 [396] [292] 0 hSpCas9 negative selection 11485794
18628526 18628549 X + 28162770 MOLM13 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 0.005783628608956093 [134] [97] 0 hSpCas9 negative selection 11485795
18564473 18564496 X + 28162770 MOLM13 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.1663880020747901 [1086] [881] 1 hSpCas9 negative selection 11485796
18584317 18584340 X - 28162770 MOLM13 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 1.0289218654669972 [384] [567] 7 hSpCas9 negative selection 11485797
18587997 18588020 X + 28162770 HEL viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 1.1785417201021906 [397] [576] 9 hSpCas9 negative selection 11655154
18603957 18603980 X + 28162770 HEL viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.1348317579442303 [400] [281] 1 hSpCas9 negative selection 11655155
18604371 18604394 X + 28162770 HEL viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 -0.42630281242929446 [106] [50] -3 hSpCas9 negative selection 11655156
18604804 18604827 X + 28162770 HEL viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 1.0506694447849407 [406] [539] 8 hSpCas9 negative selection 11655157
18609549 18609572 X + 28162770 HEL viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.5067611624813823 [188] [171] 4 hSpCas9 negative selection 11655158
18613154 18613177 X - 28162770 HEL viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.40408135630112463 [445] [377] 3 hSpCas9 negative selection 11655159
18625192 18625215 X + 28162770 HEL viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.1355684918853518 [360] [253] 1 hSpCas9 negative selection 11655160
18628526 18628549 X + 28162770 HEL viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 0.7965441680793924 [79] [88] 7 hSpCas9 negative selection 11655161
18564473 18564496 X + 28162770 HEL viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.4897397460815829 [804] [723] 4 hSpCas9 negative selection 11655162
18584317 18584340 X - 28162770 HEL viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.030881104216140542 [378] [247] 0 hSpCas9 negative selection 11655163
18587997 18588020 X + 28162770 MV411 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 1.462866024369459 [266] [619] 9 hSpCas9 negative selection 11824520
18603957 18603980 X + 28162770 MV411 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.44694354277480564 [235] [270] 4 hSpCas9 negative selection 11824521
18604371 18604394 X + 28162770 MV411 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.41736255222508745 [55] [62] 4 hSpCas9 negative selection 11824522
18604804 18604827 X + 28162770 MV411 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.22625222089214736 [342] [337] 2 hSpCas9 negative selection 11824523
18609549 18609572 X + 28162770 MV411 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 -0.09263789081484647 [199] [157] 0 hSpCas9 negative selection 11824524
18613154 18613177 X - 28162770 MV411 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.3374871554251988 [294] [313] 3 hSpCas9 negative selection 11824525
18625192 18625215 X + 28162770 MV411 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.3549219774491806 [180] [194] 3 hSpCas9 negative selection 11824526
18628526 18628549 X + 28162770 MV411 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 1.1608498657866846 [102] [193] 8 hSpCas9 negative selection 11824527
18564473 18564496 X + 28162770 MV411 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.7135355389857845 [686] [948] 6 hSpCas9 negative selection 11824528
18584317 18584340 X - 28162770 MV411 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.4538884282502018 [311] [359] 4 hSpCas9 negative selection 11824529
18587997 18588020 X + 28162770 MONOMAC1 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 -0.5437683329474885 [219] [172] -4 hSpCas9 negative selection 11993886
18603957 18603980 X + 28162770 MONOMAC1 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 0.4771929917586897 [234] [374] 5 hSpCas9 negative selection 11993887
18604371 18604394 X + 28162770 MONOMAC1 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 -0.07150596497569484 [43] [47] 0 hSpCas9 negative selection 11993888
18604804 18604827 X + 28162770 MONOMAC1 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.16229121963300241 [197] [253] 1 hSpCas9 negative selection 11993889
18609549 18609572 X + 28162770 MONOMAC1 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.16692646762502086 [114] [147] 1 hSpCas9 negative selection 11993890
18613154 18613177 X - 28162770 MONOMAC1 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 -0.49615505903882995 [250] [203] -4 hSpCas9 negative selection 11993891
18625192 18625215 X + 28162770 MONOMAC1 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.3600914454648769 [156] [230] 3 hSpCas9 negative selection 11993892
18628526 18628549 X + 28162770 MONOMAC1 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 0.8253309659689005 [31] [64] 7 hSpCas9 negative selection 11993893
18564473 18564496 X + 28162770 MONOMAC1 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.49406173834932376 [440] [711] 5 hSpCas9 negative selection 11993894
18584317 18584340 X - 28162770 MONOMAC1 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.6664611530355841 [215] [392] 6 hSpCas9 negative selection 11993895
18587997 18588020 X + 28162770 OCIAML2 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 1.0891620997440892 [52] [624] 9 hSpCas9 negative selection 12163252
18603957 18603980 X + 28162770 OCIAML2 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.37806370650608867 [82] [353] -3 hSpCas9 negative selection 12163253
18604371 18604394 X + 28162770 OCIAML2 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.06280237483891293 [18] [109] 0 hSpCas9 negative selection 12163254
18604804 18604827 X + 28162770 OCIAML2 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.6262317140104278 [62] [538] 6 hSpCas9 negative selection 12163255
18609549 18609572 X + 28162770 OCIAML2 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 0.5159496589955173 [26] [213] 5 hSpCas9 negative selection 12163256
18613154 18613177 X - 28162770 OCIAML2 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 1.0425969218800804 [66] [764] 8 hSpCas9 negative selection 12163257
18625192 18625215 X + 28162770 OCIAML2 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 1.2392909459098163 [34] [457] 9 hSpCas9 negative selection 12163258
18628526 18628549 X + 28162770 OCIAML2 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -1.055592325963317 [14] [39] -6 hSpCas9 negative selection 12163259
18564473 18564496 X + 28162770 OCIAML2 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.6268217130129818 [126] [1086] 6 hSpCas9 negative selection 12163260
18584317 18584340 X - 28162770 OCIAML2 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5053532936393033 [52] [416] 5 hSpCas9 negative selection 12163261
18587997 18588020 X + 28162770 OCIAML3 viability ATTCTTGGGGAGCTTAGCGATGG CDKL5 ENSG00000008086 0.48763082870019425 [72] [308] 4 hSpCas9 negative selection 12332618
18603957 18603980 X + 28162770 OCIAML3 viability GACATCCAGAACCTGAGTGTAGG CDKL5 ENSG00000008086 -0.11952167596457663 [103] [288] -1 hSpCas9 negative selection 12332619
18604371 18604394 X + 28162770 OCIAML3 viability AGGACCAAGGCCAAAAGCCATGG CDKL5 ENSG00000008086 0.7733634253243662 [24] [128] 7 hSpCas9 negative selection 12332620
18604804 18604827 X + 28162770 OCIAML3 viability GAAGCTTGAGCATAGGGCAAGGG CDKL5 ENSG00000008086 0.7990327566821495 [94] [498] 7 hSpCas9 negative selection 12332621
18609549 18609572 X + 28162770 OCIAML3 viability AGAGTTGGTAGCTTTTACAGAGG CDKL5 ENSG00000008086 -0.38964914181797694 [45] [105] -3 hSpCas9 negative selection 12332622
18613154 18613177 X - 28162770 OCIAML3 viability GAATTGTCTGGACGTGGAGATGG CDKL5 ENSG00000008086 0.28195109573246424 [87] [322] 2 hSpCas9 negative selection 12332623
18625192 18625215 X + 28162770 OCIAML3 viability CAAGCAGCAGACCAAAGGAGTGG CDKL5 ENSG00000008086 0.5916355948650796 [70] [322] 5 hSpCas9 negative selection 12332624
18628526 18628549 X + 28162770 OCIAML3 viability CGGGAGCAGCAACATCCGGCAGG CDKL5 ENSG00000008086 -0.2720795454368008 [21] [54] -2 hSpCas9 negative selection 12332625
18564473 18564496 X + 28162770 OCIAML3 viability GCAGGAAACACATGAAATTGTGG CDKL5 ENSG00000008086 0.3152268957526547 [204] [769] 3 hSpCas9 negative selection 12332626
18584317 18584340 X - 28162770 OCIAML3 viability TGGGGACCGATACCATCTGGTGG CDKL5 ENSG00000008086 0.5228561173667353 [79] [346] 5 hSpCas9 negative selection 12332627