Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1201
• Symbol: CLN3
• Description: CLN3 lysosomal/endosomal transmembrane protein, battenin

DataSource: http://genomecrispr.dkfz.de/#!/results/CLN3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
28491733	28491756	16	-	26472758	Jiyoye	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.8338327179979216	[77]	[32]	-5	hSpCas9	negative selection	33429
28487518	28487541	16	+	26472758	Jiyoye	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.4796140080461356	[97]	[52]	-3	hSpCas9	negative selection	33430
28484024	28484047	16	-	26472758	Jiyoye	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.45297907111899816	[185]	[191]	3	hSpCas9	negative selection	33431
28482144	28482167	16	+	26472758	Jiyoye	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-2.299777643593893	[110]	[16]	-8	hSpCas9	negative selection	33432
28491489	28491512	16	-	26472758	Jiyoye	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	33433
28482326	28482349	16	-	26472758	Jiyoye	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	0.5296593880308684	[78]	[85]	4	hSpCas9	negative selection	33434
28477796	28477819	16	+	26472758	Jiyoye	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	1.1046126114854422	[36]	[59]	7	hSpCas9	negative selection	33435
28477749	28477772	16	+	26472758	Jiyoye	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-2.3116428659500734	[78]	[11]	-8	hSpCas9	negative selection	33436
28491518	28491541	16	+	26472758	Jiyoye	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-2.042132019857717	[70]	[12]	-8	hSpCas9	negative selection	33437
28487699	28487722	16	+	26472758	Jiyoye	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	-0.24870890514590005	[270]	[171]	-2	hSpCas9	negative selection	33438
28491733	28491756	16	-	26472758	KBM7	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.6831784985393985	[293,162]	[209,130]	7	hSpCas9	negative selection	224547
28487518	28487541	16	+	26472758	KBM7	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.14557297523411566	[361,350]	[109,253]	1	hSpCas9	negative selection	224548
28484024	28484047	16	-	26472758	KBM7	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.015343200510520905	[725,466]	[372,182]	0	hSpCas9	negative selection	224549
28482144	28482167	16	+	26472758	KBM7	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-1.7586980296689045	[219,202]	[49,10]	-8	hSpCas9	negative selection	224550
28491489	28491512	16	-	26472758	KBM7	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-1.1582980694555838	[68,44]	[5,16]	-7	hSpCas9	negative selection	224551
28482326	28482349	16	-	26472758	KBM7	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	0.3082827203704306	[473,453]	[197,335]	3	hSpCas9	negative selection	224552
28477796	28477819	16	+	26472758	KBM7	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	-0.41420057868751425	[212,199]	[44,97]	-4	hSpCas9	negative selection	224553
28477749	28477772	16	+	26472758	KBM7	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-0.7736977219854155	[149,192]	[47,47]	-6	hSpCas9	negative selection	224554
28491518	28491541	16	+	26472758	KBM7	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.015926197994411417	[89,105]	[23,65]	0	hSpCas9	negative selection	224555
28487699	28487722	16	+	26472758	KBM7	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.34084266207215397	[826,1027]	[605,520]	3	hSpCas9	negative selection	224556
28491733	28491756	16	-	26472758	Raji	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.04129434491582695	[66]	[15]	0	hSpCas9	negative selection	415665
28487518	28487541	16	+	26472758	Raji	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.976139002095347	[137]	[62]	8	hSpCas9	negative selection	415666
28484024	28484047	16	-	26472758	Raji	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.006358630675588811	[276]	[63]	0	hSpCas9	negative selection	415667
28482144	28482167	16	+	26472758	Raji	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-3.7422821915419693	[172]	[2]	-9	hSpCas9	negative selection	415668
28491489	28491512	16	-	26472758	Raji	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.2145445595137634	[9]	[1]	-2	hSpCas9	negative selection	415669
28482326	28482349	16	-	26472758	Raji	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.050157741612880544	[231]	[51]	0	hSpCas9	negative selection	415670
28477796	28477819	16	+	26472758	Raji	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	-0.08024346780217173	[122]	[26]	0	hSpCas9	negative selection	415671
28477749	28477772	16	+	26472758	Raji	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	1.5455046477654846	[30]	[20]	9	hSpCas9	negative selection	415672
28491518	28491541	16	+	26472758	Raji	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.770348548096029	[47]	[18]	7	hSpCas9	negative selection	415673
28487699	28487722	16	+	26472758	Raji	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.25873515215782095	[442]	[122]	2	hSpCas9	negative selection	415674
28491733	28491756	16	-	26472758	K562	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.029405836695596488	[129]	[111]	0	hSpCas9	negative selection	606783
28487518	28487541	16	+	26472758	K562	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.10518293029527481	[249]	[226]	0	hSpCas9	negative selection	606784
28484024	28484047	16	-	26472758	K562	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.18712550261893723	[487]	[468]	1	hSpCas9	negative selection	606785
28482144	28482167	16	+	26472758	K562	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-5.113133276951636	[204]	[4]	-9	hSpCas9	negative selection	606786
28491489	28491512	16	-	26472758	K562	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-5.31017012401119	[46]	[0]	-9	hSpCas9	negative selection	606787
28482326	28482349	16	-	26472758	K562	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.19741883095611198	[325]	[239]	-1	hSpCas9	negative selection	606788
28477796	28477819	16	+	26472758	K562	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.02599520853294457	[241]	[207]	0	hSpCas9	negative selection	606789
28477749	28477772	16	+	26472758	K562	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	0.3803021557482198	[80]	[88]	3	hSpCas9	negative selection	606790
28491518	28491541	16	+	26472758	K562	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	1.0688471630829925	[47]	[84]	8	hSpCas9	negative selection	606791
28487699	28487722	16	+	26472758	K562	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.5033014902297734	[869]	[1040]	4	hSpCas9	negative selection	606792
28486367	28486390	16	+	26627737	DLD1	viability	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.01277975441959217	[561]	[219,168,146]	0	hSpCas9	negative selection	793433
28486632	28486655	16	+	26627737	DLD1	viability	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.2839478722097296	[514]	[232,207,153]	3	hSpCas9	negative selection	793434
28487519	28487542	16	+	26627737	DLD1	viability	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.555920561785924	[203]	[57,90,126]	5	hSpCas9	negative selection	793435
28488652	28488675	16	-	26627737	DLD1	viability	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	1.181657241131838	[231]	[227,152,118]	9	hSpCas9	negative selection	793436
28489311	28489334	16	-	26627737	DLD1	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.1700695093970519	[1102]	[261,451,443]	1	hSpCas9	negative selection	793437
28491492	28491515	16	-	26627737	DLD1	viability	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.6824019320348637	[495]	[255,228,258]	6	hSpCas9	negative selection	793438
28486367	28486390	16	+	26627737	GBM cells	viability after 5 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.08111720610643469	[155]	[94,81]	1	hSpCas9	negative selection	875748
28486632	28486655	16	+	26627737	GBM cells	viability after 5 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.35944107264731207	[358]	[187,305]	5	hSpCas9	negative selection	875749
28487519	28487542	16	+	26627737	GBM cells	viability after 5 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.5395858081931293	[126]	[103,93]	7	hSpCas9	negative selection	875750
28488652	28488675	16	-	26627737	GBM cells	viability after 5 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.3277571736895598	[181]	[107,136]	5	hSpCas9	negative selection	875751
28489311	28489334	16	-	26627737	GBM cells	viability after 5 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.19666378509654558	[701]	[291,364]	-3	hSpCas9	negative selection	875752
28491492	28491515	16	-	26627737	GBM cells	viability after 5 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.5604179304798349	[207]	[147,180]	7	hSpCas9	negative selection	875753
28486367	28486390	16	+	26627737	GBM cells	viability after 13 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.4659772085249399	[155]	[149,89]	6	hSpCas9	negative selection	958063
28486632	28486655	16	+	26627737	GBM cells	viability after 13 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.14393537380116972	[358]	[319,129]	1	hSpCas9	negative selection	958064
28487519	28487542	16	+	26627737	GBM cells	viability after 13 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.14930877838714873	[126]	[49,71]	-2	hSpCas9	negative selection	958065
28488652	28488675	16	-	26627737	GBM cells	viability after 13 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.827397513063158	[181]	[220,137]	8	hSpCas9	negative selection	958066
28489311	28489334	16	-	26627737	GBM cells	viability after 13 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.0563653740991803	[701]	[405,333]	0	hSpCas9	negative selection	958067
28491492	28491515	16	-	26627737	GBM cells	viability after 13 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.7061475060069966	[207]	[139,219]	8	hSpCas9	negative selection	958068
28486367	28486390	16	+	26627737	GBM cells	viability after 21 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.020350063900576476	[155]	[86,84]	0	hSpCas9	negative selection	1040378
28486632	28486655	16	+	26627737	GBM cells	viability after 21 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	-0.19275709807627045	[358]	[178,162]	-2	hSpCas9	negative selection	1040379
28487519	28487542	16	+	26627737	GBM cells	viability after 21 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.8736605620021878	[126]	[33,40]	-6	hSpCas9	negative selection	1040380
28488652	28488675	16	-	26627737	GBM cells	viability after 21 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	1.4330145116137571	[181]	[290,244]	9	hSpCas9	negative selection	1040381
28489311	28489334	16	-	26627737	GBM cells	viability after 21 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.5415965923256083	[701]	[551,557]	5	hSpCas9	negative selection	1040382
28491492	28491515	16	-	26627737	GBM cells	viability after 21 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.8082593740847546	[207]	[188,205]	7	hSpCas9	negative selection	1040383
28486367	28486390	16	+	26627737	RPE1	viability after 9 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.842455520326471	[502]	[184,407]	5	hSpCas9	negative selection	1122693
28486632	28486655	16	+	26627737	RPE1	viability after 9 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.1721521128155223	[865]	[263,358]	1	hSpCas9	negative selection	1122694
28487519	28487542	16	+	26627737	RPE1	viability after 9 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-2.240131000077061	[914]	[2,134]	-9	hSpCas9	negative selection	1122695
28488652	28488675	16	-	26627737	RPE1	viability after 9 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.18510295181470943	[538]	[176,210]	1	hSpCas9	negative selection	1122696
28489311	28489334	16	-	26627737	RPE1	viability after 9 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.25246318440949733	[1647]	[542,706]	1	hSpCas9	negative selection	1122697
28491492	28491515	16	-	26627737	RPE1	viability after 9 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.18733976333276414	[1446]	[444,336]	-1	hSpCas9	negative selection	1122698
28486367	28486390	16	+	26627737	RPE1	viability after 12 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	1.2730778025419434	[502]	[380,268]	7	hSpCas9	negative selection	1205008
28486632	28486655	16	+	26627737	RPE1	viability after 12 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.10185766686295097	[865]	[187,314]	0	hSpCas9	negative selection	1205009
28487519	28487542	16	+	26627737	RPE1	viability after 12 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-1.5243873433238815	[914]	[15,158]	-8	hSpCas9	negative selection	1205010
28488652	28488675	16	-	26627737	RPE1	viability after 12 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.4565217314052674	[538]	[290,100]	3	hSpCas9	negative selection	1205011
28489311	28489334	16	-	26627737	RPE1	viability after 12 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.17168060398506912	[1647]	[403,598]	1	hSpCas9	negative selection	1205012
28491492	28491515	16	-	26627737	RPE1	viability after 12 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.427526882020702	[1446]	[273,304]	-3	hSpCas9	negative selection	1205013
28486367	28486390	16	+	26627737	RPE1	viability after 15 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.6748314684004327	[502]	[274,180]	4	hSpCas9	negative selection	1287323
28486632	28486655	16	+	26627737	RPE1	viability after 15 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	-0.16396942521631241	[865]	[209,226]	-1	hSpCas9	negative selection	1287324
28487519	28487542	16	+	26627737	RPE1	viability after 15 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-1.5724479193559282	[914]	[0,169]	-7	hSpCas9	negative selection	1287325
28488652	28488675	16	-	26627737	RPE1	viability after 15 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.6350279207894531	[538]	[248,224]	4	hSpCas9	negative selection	1287326
28489311	28489334	16	-	26627737	RPE1	viability after 15 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.2588314049581031	[1647]	[456,654]	1	hSpCas9	negative selection	1287327
28491492	28491515	16	-	26627737	RPE1	viability after 15 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.08626226872230114	[1446]	[656,219]	0	hSpCas9	negative selection	1287328
28486367	28486390	16	+	26627737	RPE1	viability after 18 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.9283348472348051	[502]	[369,138]	5	hSpCas9	negative selection	1369638
28486632	28486655	16	+	26627737	RPE1	viability after 18 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.5406147539924521	[865]	[352,325]	3	hSpCas9	negative selection	1369639
28487519	28487542	16	+	26627737	RPE1	viability after 18 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-2.136946490982849	[914]	[1,113]	-8	hSpCas9	negative selection	1369640
28488652	28488675	16	-	26627737	RPE1	viability after 18 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.2911449863425403	[538]	[162,193]	1	hSpCas9	negative selection	1369641
28489311	28489334	16	-	26627737	RPE1	viability after 18 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	1.0832227017101297	[1647]	[688,1212]	6	hSpCas9	negative selection	1369642
28491492	28491515	16	-	26627737	RPE1	viability after 18 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.03060703707142265	[1446]	[463,294]	0	hSpCas9	negative selection	1369643
28486367	28486390	16	+	26627737	HeLa	viability after 8 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.11245445511686625	[150]	[139,27,60]	1	hSpCas9	negative selection	1451953
28486632	28486655	16	+	26627737	HeLa	viability after 8 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.1532874122385416	[496]	[106,401,186]	1	hSpCas9	negative selection	1451954
28487519	28487542	16	+	26627737	HeLa	viability after 8 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.8036625064444816	[214]	[62,77,23]	-7	hSpCas9	negative selection	1451955
28488652	28488675	16	-	26627737	HeLa	viability after 8 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-0.0027919279170247613	[280]	[155,160,60]	0	hSpCas9	negative selection	1451956
28489311	28489334	16	-	26627737	HeLa	viability after 8 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.362638330890236	[781]	[644,479,246]	3	hSpCas9	negative selection	1451957
28491492	28491515	16	-	26627737	HeLa	viability after 8 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.0715763585249578	[552]	[226,385,83]	0	hSpCas9	negative selection	1451958
28486367	28486390	16	+	26627737	HeLa	viability after 12 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.3379322435816725	[150]	[41,38,67]	-3	hSpCas9	negative selection	1534268
28486632	28486655	16	+	26627737	HeLa	viability after 12 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	-0.032835831653167835	[496]	[283,84,247]	0	hSpCas9	negative selection	1534269
28487519	28487542	16	+	26627737	HeLa	viability after 12 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.4600711186818316	[214]	[28,80,80]	-4	hSpCas9	negative selection	1534270
28488652	28488675	16	-	26627737	HeLa	viability after 12 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.450041356599023	[280]	[213,106,161]	4	hSpCas9	negative selection	1534271
28489311	28489334	16	-	26627737	HeLa	viability after 12 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.04078682868080963	[781]	[406,270,327]	0	hSpCas9	negative selection	1534272
28491492	28491515	16	-	26627737	HeLa	viability after 12 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.6861779776561443	[552]	[570,188,367]	5	hSpCas9	negative selection	1534273
28486367	28486390	16	+	26627737	HeLa	viability after 15 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.9084969068917611	[150]	[106,90,150]	7	hSpCas9	negative selection	1616583
28486632	28486655	16	+	26627737	HeLa	viability after 15 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.3007308640481656	[496]	[175,197,384]	2	hSpCas9	negative selection	1616584
28487519	28487542	16	+	26627737	HeLa	viability after 15 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.22690651498689207	[214]	[36,62,128]	-2	hSpCas9	negative selection	1616585
28488652	28488675	16	-	26627737	HeLa	viability after 15 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.2904559003369369	[280]	[112,155,151]	2	hSpCas9	negative selection	1616586
28489311	28489334	16	-	26627737	HeLa	viability after 15 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.24384667911201652	[781]	[367,434,323]	2	hSpCas9	negative selection	1616587
28491492	28491515	16	-	26627737	HeLa	viability after 15 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.4847063793625379	[552]	[438,182,321]	4	hSpCas9	negative selection	1616588
28486367	28486390	16	+	26627737	HeLa	viability after 18 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.9131571345047352	[150]	[75,70,150]	7	hSpCas9	negative selection	1698898
28486632	28486655	16	+	26627737	HeLa	viability after 18 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.34339563636257187	[496]	[122,175,384]	3	hSpCas9	negative selection	1698899
28487519	28487542	16	+	26627737	HeLa	viability after 18 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.19123605835496882	[214]	[26,53,128]	-2	hSpCas9	negative selection	1698900
28488652	28488675	16	-	26627737	HeLa	viability after 18 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.30334928483021056	[280]	[71,136,151]	2	hSpCas9	negative selection	1698901
28489311	28489334	16	-	26627737	HeLa	viability after 18 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.22867884025268548	[781]	[240,357,323]	2	hSpCas9	negative selection	1698902
28491492	28491515	16	-	26627737	HeLa	viability after 18 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.48381668735155303	[552]	[288,157,321]	4	hSpCas9	negative selection	1698903
28486367	28486390	16	+	26627737	HCT116	viability after 6 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-1.9089978092799298	[232]	[21,2]	-8	hSpCas9	negative selection	1781213
28486632	28486655	16	+	26627737	HCT116	viability after 6 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	1.5665950850741217	[453]	[164,236]	7	hSpCas9	negative selection	1781214
28487519	28487542	16	+	26627737	HCT116	viability after 6 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.6856763654693516	[163]	[25,49]	4	hSpCas9	negative selection	1781215
28488652	28488675	16	-	26627737	HCT116	viability after 6 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	2.7534887807838033	[460]	[52,728]	9	hSpCas9	negative selection	1781216
28489311	28489334	16	-	26627737	HCT116	viability after 6 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.512882186964996	[1919]	[547,365]	3	hSpCas9	negative selection	1781217
28491492	28491515	16	-	26627737	HCT116	viability after 6 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.7929011542053024	[1057]	[231,20]	-4	hSpCas9	negative selection	1781218
28486367	28486390	16	+	26627737	HCT116	viability after 8 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.0596265140200436	[164]	[58,77,145]	0	hSpCas9	negative selection	1863528
28486632	28486655	16	+	26627737	HCT116	viability after 8 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.35861356915865117	[326]	[196,223,270]	4	hSpCas9	negative selection	1863529
28487519	28487542	16	+	26627737	HCT116	viability after 8 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-1.2499095218668226	[235]	[60,35,66]	-9	hSpCas9	negative selection	1863530
28488652	28488675	16	-	26627737	HCT116	viability after 8 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.9479682955507566	[106]	[128,139,72]	8	hSpCas9	negative selection	1863531
28489311	28489334	16	-	26627737	HCT116	viability after 8 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.3427543261981556	[676]	[596,394,429]	4	hSpCas9	negative selection	1863532
28491492	28491515	16	-	26627737	HCT116	viability after 8 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.5156576656830225	[338]	[308,232,259]	5	hSpCas9	negative selection	1863533
28486367	28486390	16	+	26627737	HCT116	viability after 9 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.022505345262884058	[232]	[96,32]	0	hSpCas9	negative selection	1945843
28486632	28486655	16	+	26627737	HCT116	viability after 9 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.9423485307524899	[453]	[199,258]	6	hSpCas9	negative selection	1945844
28487519	28487542	16	+	26627737	HCT116	viability after 9 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.23507356941919122	[163]	[74,32]	1	hSpCas9	negative selection	1945845
28488652	28488675	16	-	26627737	HCT116	viability after 9 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.814259863614356	[460]	[111,298]	6	hSpCas9	negative selection	1945846
28489311	28489334	16	-	26627737	HCT116	viability after 9 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.6030223122893166	[1919]	[465,235]	-4	hSpCas9	negative selection	1945847
28491492	28491515	16	-	26627737	HCT116	viability after 9 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.025577866077993505	[1057]	[472,140]	0	hSpCas9	negative selection	1945848
28486367	28486390	16	+	26627737	HCT116	viability after 12 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.2570737777898221	[164]	[58,77,81]	-3	hSpCas9	negative selection	2028158
28486632	28486655	16	+	26627737	HCT116	viability after 12 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.6193596494670416	[326]	[245,199,345]	6	hSpCas9	negative selection	2028159
28487519	28487542	16	+	26627737	HCT116	viability after 12 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-1.1486717494316294	[235]	[36,35,95]	-8	hSpCas9	negative selection	2028160
28488652	28488675	16	-	26627737	HCT116	viability after 12 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	1.7222520114266262	[106]	[206,196,150]	9	hSpCas9	negative selection	2028161
28489311	28489334	16	-	26627737	HCT116	viability after 12 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.047057300051890794	[676]	[359,355,315]	0	hSpCas9	negative selection	2028162
28491492	28491515	16	-	26627737	HCT116	viability after 12 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.6144065743343989	[338]	[255,202,358]	6	hSpCas9	negative selection	2028163
28486367	28486390	16	+	26627737	HCT116	viability after 15 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.29030181149668455	[164]	[97,62,73]	-3	hSpCas9	negative selection	2110473
28486632	28486655	16	+	26627737	HCT116	viability after 15 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.40605703621415556	[326]	[237,158,346]	4	hSpCas9	negative selection	2110474
28487519	28487542	16	+	26627737	HCT116	viability after 15 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.4608224367358083	[235]	[76,49,164]	-5	hSpCas9	negative selection	2110475
28488652	28488675	16	-	26627737	HCT116	viability after 15 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	1.710108264582911	[106]	[142,243,208]	9	hSpCas9	negative selection	2110476
28489311	28489334	16	-	26627737	HCT116	viability after 15 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.36574460801827513	[676]	[270,456,743]	3	hSpCas9	negative selection	2110477
28491492	28491515	16	-	26627737	HCT116	viability after 15 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.4512079404686405	[338]	[249,151,392]	4	hSpCas9	negative selection	2110478
28486367	28486390	16	+	26627737	HCT116	viability after 18 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.23943176019236911	[164]	[76,26,102]	-2	hSpCas9	negative selection	2192788
28486632	28486655	16	+	26627737	HCT116	viability after 18 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.7865936817017762	[326]	[204,172,454]	6	hSpCas9	negative selection	2192789
28487519	28487542	16	+	26627737	HCT116	viability after 18 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.6006061593909378	[235]	[57,79,87]	-5	hSpCas9	negative selection	2192790
28488652	28488675	16	-	26627737	HCT116	viability after 18 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	1.4374554543149765	[106]	[77,193,144]	8	hSpCas9	negative selection	2192791
28489311	28489334	16	-	26627737	HCT116	viability after 18 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.1903856380819986	[676]	[378,348,394]	1	hSpCas9	negative selection	2192792
28491492	28491515	16	-	26627737	HCT116	viability after 18 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.613229580286329	[338]	[213,180,366]	5	hSpCas9	negative selection	2192793
28489368	28489391	16	+	24336569	HL60	viability	GTTGCAAAGGCCCAGCAGCCTGG	CLN3	ENSG00000188603	-0.4237874162673294	[560]	[884]	-4	hSpCas9	negative selection	2258148
28489378	28489401	16	-	24336569	HL60	viability	CCTGCTCCTTCCAGGCTGCTGGG	CLN3	ENSG00000188603	4.50349840009226	[1]	[95]	9	hSpCas9	negative selection	2258149
28491481	28491504	16	-	24336569	HL60	viability	GGAAGAACGCGGTGGGCTTCTGG	CLN3	ENSG00000188603	-0.6250101817914944	[969]	[1330]	-5	hSpCas9	negative selection	2258150
28491488	28491511	16	-	24336569	HL60	viability	GCGCATTGGAAGAACGCGGTGGG	CLN3	ENSG00000188603	-2.7908739722745404	[120]	[36]	-9	hSpCas9	negative selection	2258151
28491498	28491521	16	+	24336569	HL60	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.0693381153503263	[1243]	[2508]	0	hSpCas9	negative selection	2258152
28491509	28491532	16	+	24336569	HL60	viability	GCGCCCTGATGGTCCAACAGAGG	CLN3	ENSG00000188603	0.18901027791826877	[547]	[1321]	1	hSpCas9	negative selection	2258153
28491516	28491539	16	+	24336569	HL60	viability	GATGGTCCAACAGAGGGAGCCGG	CLN3	ENSG00000188603	0.12248472648506248	[730]	[1683]	1	hSpCas9	negative selection	2258154
28491733	28491756	16	-	24336569	HL60	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.5782087946086032	[1015]	[3209]	5	hSpCas9	negative selection	2258155
28491743	28491766	16	-	24336569	HL60	viability	GATGCGATGGGAGGCTGTGCAGG	CLN3	ENSG00000188603	0.38566190979840154	[696]	[1926]	3	hSpCas9	negative selection	2258156
28491752	28491775	16	-	24336569	HL60	viability	CCTGAACTTGATGCGATGGGAGG	CLN3	ENSG00000188603	-0.9469541648172172	[306]	[336]	-7	hSpCas9	negative selection	2258157
28489368	28489391	16	+	24336569	KBM7	viability	GTTGCAAAGGCCCAGCAGCCTGG	CLN3	ENSG00000188603	0.7548852317369084	[301]	[1389]	6	hSpCas9	negative selection	2325325
28489378	28489401	16	-	24336569	KBM7	viability	CCTGCTCCTTCCAGGCTGCTGGG	CLN3	ENSG00000188603	-0.5215797779926596	[39]	[75]	-4	hSpCas9	negative selection	2325326
28491481	28491504	16	-	24336569	KBM7	viability	GGAAGAACGCGGTGGGCTTCTGG	CLN3	ENSG00000188603	-0.0738486714269524	[743]	[1927]	0	hSpCas9	negative selection	2325327
28491488	28491511	16	-	24336569	KBM7	viability	GCGCATTGGAAGAACGCGGTGGG	CLN3	ENSG00000188603	1.9384792357581953	[10]	[114]	9	hSpCas9	negative selection	2325328
28491498	28491521	16	+	24336569	KBM7	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-1.0050864724710107	[1066]	[1449]	-6	hSpCas9	negative selection	2325329
28491509	28491532	16	+	24336569	KBM7	viability	GCGCCCTGATGGTCCAACAGAGG	CLN3	ENSG00000188603	0.35887149793860756	[455]	[1594]	3	hSpCas9	negative selection	2325330
28491516	28491539	16	+	24336569	KBM7	viability	GATGGTCCAACAGAGGGAGCCGG	CLN3	ENSG00000188603	-1.342821455335753	[955]	[1027]	-7	hSpCas9	negative selection	2325331
28491733	28491756	16	-	24336569	KBM7	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.38342507420897864	[872]	[3105]	3	hSpCas9	negative selection	2325332
28491743	28491766	16	-	24336569	KBM7	viability	GATGCGATGGGAGGCTGTGCAGG	CLN3	ENSG00000188603	-0.04323197552049485	[744]	[1971]	0	hSpCas9	negative selection	2325333
28491752	28491775	16	-	24336569	KBM7	viability	CCTGAACTTGATGCGATGGGAGG	CLN3	ENSG00000188603	0.546188849739603	[173]	[692]	5	hSpCas9	negative selection	2325334
28489072	28489095	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGTCGGAG	CLN3	ENSG00000188603	1.0128281800924883	[250,40]	[67,58]	4	dCas9-VP64	positive selection	2417007
28471365	28471388	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TACATTTGTTCCTGAGATACGGG	CLN3	ENSG00000261832	2.106789968317293	[1226,1871]	[195,2858]	7	dCas9-VP64	positive selection	2422049
28471432	28471455	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCTGGAACAAAATAAGTCAGG	CLN3	ENSG00000261832	-0.7511754091929639	[1613,1385]	[266,118]	-4	dCas9-VP64	positive selection	2422067
28492453	28492476	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTGTAAGGTCAACAGATGGGG	CLN3	ENSG00000188603	-0.12198043504077027	[297,667]	[104,90]	0	dCas9-VP64	positive selection	2423753
28492420	28492443	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAACAAAGACGACCAGCTTCAGG	CLN3	ENSG00000188603	3.2481397080988956	[587,297]	[1748,32]	8	dCas9-VP64	positive selection	2423754
28492393	28492416	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTTGAGGCAGGACTGTTTCTGG	CLN3	ENSG00000188603	0.7218629638941785	[192,107]	[28,80]	3	dCas9-VP64	positive selection	2423755
28492195	28492218	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTTTAAAACCTGCGGTTCCAGG	CLN3	ENSG00000188603	2.459469687568114	[1643,858]	[2838,75]	7	dCas9-VP64	positive selection	2423759
28492241	28492264	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCCGTGACCTTAGATCAGTGG	CLN3	ENSG00000188603	2.3165927265979303	[444,241]	[112,658]	7	dCas9-VP64	positive selection	2423760
28492152	28492175	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCACGCTCCGAAGCCGAGAAGG	CLN3	ENSG00000188603	0.2752018308185624	[329,288]	[131,27]	1	dCas9-VP64	positive selection	2423761
28480571	28480594	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCATTTTTAATAGAGACGGGG	CLN3	ENSG00000188603	-0.26285040717771335	[141,96]	[27,13]	-1	dCas9-VP64	positive selection	2431603
28489827	28489850	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCGCCTGAGGTCAGG	CLN3	ENSG00000188603	6.867551394174825	[8,20]	[680,118]	9	dCas9-VP64	positive selection	2432037
28494496	28494519	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCATTTCCCGGGCTGCAGTGGG	CLN3	ENSG00000188603	1.302731762349156	[56,17]	[7,32]	5	dCas9-VP64	positive selection	2450647
28494517	28494540	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGCTACTGTGGGCATCAGGGG	CLN3	ENSG00000188603	3.1896759615405768	[23,14]	[47,28]	8	dCas9-VP64	positive selection	2450648
28494472	28494495	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTACATCACACAGGGGACTCAGG	CLN3	ENSG00000188603	0.6429862273332803	[50,55]	[26,7]	2	dCas9-VP64	positive selection	2450649
28489826	28489849	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGCGGATCGCCTGAGGTCAG	CLN3	ENSG00000188603	-0.18430104662994673	[168,33]	[5,32]	0	dCas9-VP64	positive selection	2451996
28489072	28489095	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGTCGGAG	CLN3	ENSG00000188603	-0.03815698815020019	[56,33]	[21,6]	0	dCas9-VP64	positive selection	2512262
28471365	28471388	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TACATTTGTTCCTGAGATACGGG	CLN3	ENSG00000261832	0.13728105815386016	[1730,1988]	[631,700]	1	dCas9-VP64	positive selection	2517304
28471432	28471455	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCTGGAACAAAATAAGTCAGG	CLN3	ENSG00000261832	0.7875531147636998	[1008,957]	[677,439]	5	dCas9-VP64	positive selection	2517322
28492453	28492476	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTGTAAGGTCAACAGATGGGG	CLN3	ENSG00000188603	0.3122924901925397	[446,498]	[99,276]	2	dCas9-VP64	positive selection	2519008
28492420	28492443	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAACAAAGACGACCAGCTTCAGG	CLN3	ENSG00000188603	-0.3994959088011517	[150,330]	[63,53]	-4	dCas9-VP64	positive selection	2519009
28492393	28492416	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTTGAGGCAGGACTGTTTCTGG	CLN3	ENSG00000188603	0.3292401015776272	[133,229]	[46,99]	2	dCas9-VP64	positive selection	2519010
28492195	28492218	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTTTAAAACCTGCGGTTCCAGG	CLN3	ENSG00000188603	-0.14059679103493083	[196,425]	[109,74]	-1	dCas9-VP64	positive selection	2519014
28492241	28492264	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCCGTGACCTTAGATCAGTGG	CLN3	ENSG00000188603	-0.5904567769438187	[420,392]	[87,87]	-6	dCas9-VP64	positive selection	2519015
28492152	28492175	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCACGCTCCGAAGCCGAGAAGG	CLN3	ENSG00000188603	1.0768524029798203	[319,324]	[214,228]	7	dCas9-VP64	positive selection	2519016
28480571	28480594	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCATTTTTAATAGAGACGGGG	CLN3	ENSG00000188603	1.0123186104573552	[17,472]	[10,297]	6	dCas9-VP64	positive selection	2526858
28489827	28489850	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCGCCTGAGGTCAGG	CLN3	ENSG00000188603	2.8861339131047825	[53,23]	[20,163]	9	dCas9-VP64	positive selection	2527292
28494496	28494519	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCATTTCCCGGGCTGCAGTGGG	CLN3	ENSG00000188603	-0.5589335832297188	[68,55]	[18,7]	-5	dCas9-VP64	positive selection	2545902
28494517	28494540	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGCTACTGTGGGCATCAGGGG	CLN3	ENSG00000188603	-0.42261686584008656	[218,47]	[55,10]	-4	dCas9-VP64	positive selection	2545903
28494472	28494495	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTACATCACACAGGGGACTCAGG	CLN3	ENSG00000188603	-0.7647240939696424	[174,397]	[28,77]	-7	dCas9-VP64	positive selection	2545904
28489826	28489849	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGCGGATCGCCTGAGGTCAG	CLN3	ENSG00000188603	1.078969245028043	[31,25]	[25,14]	7	dCas9-VP64	positive selection	2547251
28487700	28487723	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.28267738575637613	[5,5]	[5,6]	6	hSpCas9	positive selection	2979833
28486578	28486601	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	0.20332982142545325	[3,3]	[2,3]	4	hSpCas9	positive selection	2979834
28491492	28491515	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.2777647306028057	[2,2]	[3,1]	6	hSpCas9	positive selection	2979835
28487520	28487543	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.0945350126130006	[3,3]	[4,2]	2	hSpCas9	positive selection	2979836
28487700	28487723	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.19304148891539108	[5,5]	[4,4]	3	hSpCas9	positive selection	3047691
28486578	28486601	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	-0.02942863165156509	[3,3]	[1,2]	0	hSpCas9	positive selection	3047692
28491492	28491515	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.39960842728812296	[2,2]	[2,2]	7	hSpCas9	positive selection	3047693
28487520	28487543	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.17203897197563936	[3,3]	[4,0]	-3	hSpCas9	positive selection	3047694
28487521	28487544		-	24336571	A375	resistance to PLX after 7 days	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.27940736818278733	[1,3]	[2,3]	7	hSpCas9	positive selection	3106135
28482123	28482146		-	24336571	A375	resistance to PLX after 7 days	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	-0.2455461729597456	[11,11]	[15,3]	-7	hSpCas9	positive selection	3106137
28482128	28482151		+	24336571	A375	resistance to PLX after 7 days	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	-0.05741778554820942	[3,3]	[4,1]	-2	hSpCas9	positive selection	3106138
28487521	28487544		-	24336571	A375	resistance to PLX after 14 days	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.49009197471618915	[2,4]	[1,1]	4	hSpCas9	positive selection	3163928
28482123	28482146		-	24336571	A375	resistance to PLX after 14 days	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.1391560105298683	[13,12]	[6,5]	1	hSpCas9	positive selection	3163930
28482128	28482151		+	24336571	A375	resistance to PLX after 14 days	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	0.6383361853624779	[4,3]	[3,1]	6	hSpCas9	positive selection	3163931
28487521	28487544		-	24336571	A375	viability after 7 days	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.47187257355662626	[4]	[1,3]	-6	hSpCas9	negative selection	3221721
28482123	28482146		-	24336571	A375	viability after 7 days	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	2.0003522680592134	[2]	[11,11]	9	hSpCas9	negative selection	3221723
28482128	28482151		+	24336571	A375	viability after 7 days	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	1.0700224902164086	[1]	[3,3]	9	hSpCas9	negative selection	3221724
28487521	28487544		-	24336571	A375	viability after 14 days	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.20233664927619088	[4]	[2,4]	-2	hSpCas9	negative selection	3279514
28482123	28482146		-	24336571	A375	viability after 14 days	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	2.1961865370582947	[2]	[13,12]	9	hSpCas9	negative selection	3279516
28482128	28482151		+	24336571	A375	viability after 14 days	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	1.1962752513968993	[1]	[4,3]	9	hSpCas9	negative selection	3279517
28491498	28491521	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	1.3122840881231341	[77,44]	[0,0]	5	hSpCas9	positive selection	3343584
28482123	28482146	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	-0.5263033387475179	[196,243]	[0,0]	-3	hSpCas9	positive selection	3343585
28489311	28489334	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	1.7025367486240397	[47,45]	[0,0]	6	hSpCas9	positive selection	3343586
28491489	28491512	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	1.449971289388231	[111,111]	[1,1]	6	hSpCas9	positive selection	3362806
28487521	28487544	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3362807
28487516	28487539	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	1.5849008694743394	[50,50]	[0,0]	6	hSpCas9	positive selection	3362808
28487699	28487722	16	+	26780180	HT29	viability (Avana library 4 designs)	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	-0.314019270650427	[]	[]	-5	hSpCas9	negative selection	3416268
28486577	28486600	16	+	26780180	HT29	viability (Avana library 4 designs)	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	1.28778564729893	[]	[]	5	hSpCas9	negative selection	3416269
28491492	28491515	16	-	26780180	HT29	viability (Avana library 4 designs)	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.05782719030579	[]	[]	4	hSpCas9	negative selection	3416270
28487519	28487542	16	+	26780180	HT29	viability (Avana library 4 designs)	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	1.47553592086514	[]	[]	6	hSpCas9	negative selection	3416271
28491492	28491515	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	4.18454620965642	[]	[]	7	hSpCas9	negative selection	3493717
28486577	28486600	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	2.1473093518053	[]	[]	3	hSpCas9	negative selection	3493718
28487519	28487542	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	2.0475074523278	[]	[]	3	hSpCas9	negative selection	3493719
28487699	28487722	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	1.85922769180086	[]	[]	2	hSpCas9	negative selection	3493720
28491733	28491756	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.196666623448754	[]	[]	0	hSpCas9	negative selection	3493721
28491518	28491541	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	1.09667396338375	[]	[]	1	hSpCas9	negative selection	3493722
28491492	28491515	16	-	26780180	A375	viability (Avana lentiGuide)	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-1.26756628785228	[]	[]	-2	hSpCas9	negative selection	3602376
28486577	28486600	16	+	26780180	A375	viability (Avana lentiGuide)	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	6.6240213864806	[]	[]	5	hSpCas9	negative selection	3602377
28487519	28487542	16	+	26780180	A375	viability (Avana lentiGuide)	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	4.40711925555753	[]	[]	4	hSpCas9	negative selection	3602378
28487699	28487722	16	+	26780180	A375	viability (Avana lentiGuide)	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	-0.510353917096046	[]	[]	0	hSpCas9	negative selection	3602379
28491733	28491756	16	-	26780180	A375	viability (Avana lentiGuide)	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-3.4265852358887	[]	[]	-6	hSpCas9	negative selection	3602380
28491518	28491541	16	+	26780180	A375	viability (Avana lentiGuide)	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	2.59796219887206	[]	[]	2	hSpCas9	negative selection	3602381
28491492	28491515	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.0262921274323559	[4]	[3,4]	0	hSpCas9	positive selection	3711035
28486577	28486600	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	-0.01596136294503267	[4]	[4,4]	0	hSpCas9	positive selection	3711036
28487519	28487542	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.1292514137624819	[5]	[4,4]	-2	hSpCas9	positive selection	3711037
28487699	28487722	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.19865603990673486	[6]	[7,7]	5	hSpCas9	positive selection	3711038
28491733	28491756	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.022760661982196617	[3]	[3,2]	0	hSpCas9	positive selection	3711039
28491518	28491541	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.20489109612602857	[4]	[3,2]	-3	hSpCas9	positive selection	3711040
28491492	28491515	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.36562823178914916	[4]	[2,2]	-5	hSpCas9	positive selection	3819642
28486577	28486600	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGGGTAGAAGGCAGTGAGGG	CLN3	ENSG00000188603	-1.085041248812226	[5]	[2,0]	-8	hSpCas9	positive selection	3819643
28487519	28487542	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.4262445226493827	[6]	[4,2]	-5	hSpCas9	positive selection	3819644
28487699	28487722	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.20656845288863296	[7]	[7,7]	5	hSpCas9	positive selection	3819645
28491733	28491756	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.011302987944977666	[4]	[3,3]	0	hSpCas9	positive selection	3819646
28491518	28491541	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-1.692549267412464	[4]	[0,0]	-9	hSpCas9	positive selection	3819647
28487516	28487539	16	+	26780180	A375	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	1.56779888739917	[]	[]	8	hSpCas9	negative selection	3927642
28489311	28489334	16	-	26780180	A375	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	1.18089748576134	[]	[]	6	hSpCas9	negative selection	3927643
28487521	28487544	16	-	26780180	A375	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.892496765872251	[]	[]	4	hSpCas9	negative selection	3927644
28491489	28491512	16	-	26780180	A375	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	1.10978320697908	[]	[]	5	hSpCas9	negative selection	3927645
28482123	28482146	16	-	26780180	A375	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.208207373176118	[]	[]	0	hSpCas9	negative selection	3927646
28491498	28491521	16	+	26780180	A375	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	1.24043223370507	[]	[]	6	hSpCas9	negative selection	3927647
28487516	28487539	16	+	26780180	HT29	viability (GeCKOv2 library)	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	2.33099786379008	[]	[]	9	hSpCas9	negative selection	4035608
28489311	28489334	16	-	26780180	HT29	viability (GeCKOv2 library)	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	1.50042033068671	[]	[]	7	hSpCas9	negative selection	4035609
28487521	28487544	16	-	26780180	HT29	viability (GeCKOv2 library)	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	1.49252831702273	[]	[]	7	hSpCas9	negative selection	4035610
28491489	28491512	16	-	26780180	HT29	viability (GeCKOv2 library)	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.996396986599673	[]	[]	4	hSpCas9	negative selection	4035611
28482123	28482146	16	-	26780180	HT29	viability (GeCKOv2 library)	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.433141756707387	[]	[]	1	hSpCas9	negative selection	4035612
28491498	28491521	16	+	26780180	HT29	viability (GeCKOv2 library)	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	1.48934724883714	[]	[]	7	hSpCas9	negative selection	4035613
28487521	28487544	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.15388915428271954	[2]	[1,0]	-4	hSpCas9	positive selection	4128276
28482123	28482146	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.019180784151271696	[4]	[2,2]	0	hSpCas9	positive selection	4128278
28482128	28482151	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	-0.3853593552439373	[2]	[0,1]	-7	hSpCas9	positive selection	4128279
28487521	28487544	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.28726283550919185	[1]	[1,0,0,0]	2	hSpCas9	positive selection	4192298
28482123	28482146	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	1.075981746518333	[4]	[4,4,3,3]	7	hSpCas9	positive selection	4192300
28482128	28482151	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAACGGATGCGACAGCAGCGG	CLN3	ENSG00000188603	-0.27578528109393485	[3]	[2,0,0,0]	-4	hSpCas9	positive selection	4192301
28491498	28491521	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.6911047746872936	[2]	[0,0]	-9	hSpCas9	positive selection	4263771
28482123	28482146	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.24076183615387026	[3]	[3,2]	5	hSpCas9	positive selection	4263772
28489311	28489334	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.17173048730010188	[2]	[2,1]	3	hSpCas9	positive selection	4263773
28491489	28491512	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.3988737389377449	[2]	[1,0]	-7	hSpCas9	positive selection	4328044
28487521	28487544	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.2778407101573014	[2]	[0,1]	-5	hSpCas9	positive selection	4328045
28487516	28487539	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.9133788376789795	[2]	[0,0]	-9	hSpCas9	positive selection	4328046
28488636	28488658	16	+	27760321	OCIAML3	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.4227731652454507	[664,571]	[557,761]	5	hSpCas9	negative selection	4390081
28489305	28489327	16	+	27760321	OCIAML3	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.30819012115749234	[940,787]	[624,1105]	3	hSpCas9	negative selection	4390082
28491492	28491514	16	-	27760321	OCIAML3	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.20143574093927358	[537,397]	[354,497]	2	hSpCas9	negative selection	4390083
28486636	28486658	16	+	27760321	OCIAML3	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.8994374905149671	[3,0]	[0,0]	-7	hSpCas9	negative selection	4390084
28487519	28487541	16	+	27760321	OCIAML3	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.035526404530019484	[527,442]	[299,458]	0	hSpCas9	negative selection	4390085
28488636	28488658	16	+	27760321	OCIAML2	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.6255202205828586	[664,571]	[669,900]	8	hSpCas9	negative selection	4473544
28489305	28489327	16	+	27760321	OCIAML2	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.725878260079096	[940,787]	[1164,1134]	8	hSpCas9	negative selection	4473545
28491492	28491514	16	-	27760321	OCIAML2	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.15334616645067162	[537,397]	[336,522]	2	hSpCas9	negative selection	4473546
28486636	28486658	16	+	27760321	OCIAML2	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.9481828557800158	[3,0]	[0,0]	-7	hSpCas9	negative selection	4473547
28487519	28487541	16	+	27760321	OCIAML2	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.14730822638446797	[527,442]	[275,454]	-2	hSpCas9	negative selection	4473548
28488636	28488658	16	+	27760321	MV411	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.5498309178160573	[664,571]	[558,650]	4	hSpCas9	negative selection	4557007
28489305	28489327	16	+	27760321	MV411	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.2492718771245187	[940,787]	[413,1067]	1	hSpCas9	negative selection	4557008
28491492	28491514	16	-	27760321	MV411	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.9297124456328401	[537,397]	[347,935]	6	hSpCas9	negative selection	4557009
28486636	28486658	16	+	27760321	MV411	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.6543589216002852	[3,0]	[0,0]	-4	hSpCas9	negative selection	4557010
28487519	28487541	16	+	27760321	MV411	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.10339310062589177	[527,442]	[393,265]	0	hSpCas9	negative selection	4557011
28488636	28488658	16	+	27760321	HL60	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.5697847276060154	[664,571]	[772,720]	6	hSpCas9	negative selection	4640470
28489305	28489327	16	+	27760321	HL60	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.9458275146403291	[940,787]	[1318,1392]	8	hSpCas9	negative selection	4640471
28491492	28491514	16	-	27760321	HL60	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.26888944367469914	[537,397]	[372,544]	3	hSpCas9	negative selection	4640472
28486636	28486658	16	+	27760321	HL60	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.9622290833944218	[3,0]	[0,0]	-7	hSpCas9	negative selection	4640473
28487519	28487541	16	+	27760321	HL60	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.014547448810584035	[527,442]	[466,326]	0	hSpCas9	negative selection	4640474
28488636	28488658	16	+	27760321	HT1080	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	1.168050615387151	[571,446]	[521,383]	6	hSpCas9	negative selection	4723933
28489305	28489327	16	+	27760321	HT1080	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	-8.126481474480457	[787,614]	[0,0]	-9	hSpCas9	negative selection	4723934
28491492	28491514	16	-	27760321	HT1080	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.3633187229097945	[397,310]	[391,331]	7	hSpCas9	negative selection	4723935
28486636	28486658	16	+	27760321	HT1080	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	10.768888598313039	[0,0]	[660,754]	9	hSpCas9	negative selection	4723936
28487519	28487541	16	+	27760321	HT1080	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	1.9939448737976464	[442,345]	[615,636]	9	hSpCas9	negative selection	4723937
28488636	28488658	16	+	27760321	HT29	viability after 7 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.17354751902864196	[571,446]	[913,698,630]	2	hSpCas9	negative selection	4807396
28489305	28489327	16	+	27760321	HT29	viability after 7 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.40016764866764754	[787,614]	[1499,1076,1040]	6	hSpCas9	negative selection	4807397
28491492	28491514	16	-	27760321	HT29	viability after 7 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.37515312281007995	[397,310]	[762,531,504]	6	hSpCas9	negative selection	4807398
28486636	28486658	16	+	27760321	HT29	viability after 7 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4807399
28487519	28487541	16	+	27760321	HT29	viability after 7 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.4122245073137899	[442,345]	[863,830,365]	6	hSpCas9	negative selection	4807400
28488636	28488658	16	+	27760321	HT29	viability after 25 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.8003928438458389	[571,446]	[1130,961,931]	8	hSpCas9	negative selection	4890859
28489305	28489327	16	+	27760321	HT29	viability after 25 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.8084341635577299	[787,614]	[842,1646,1795]	8	hSpCas9	negative selection	4890860
28491492	28491514	16	-	27760321	HT29	viability after 25 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.2329467978270807	[397,310]	[623,818,1488]	9	hSpCas9	negative selection	4890861
28486636	28486658	16	+	27760321	HT29	viability after 25 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	0.5670770358587518	[0,0]	[2,0,0]	6	hSpCas9	negative selection	4890862
28487519	28487541	16	+	27760321	HT29	viability after 25 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.6278403365696117	[442,345]	[667,698,726]	7	hSpCas9	negative selection	4890863
28488636	28488658	16	+	27760321	HT29	viability after 22 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.551869171860523	[571,446]	[970,929,684]	6	hSpCas9	negative selection	4974322
28489305	28489327	16	+	27760321	HT29	viability after 22 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.8964896689233457	[787,614]	[1285,1729,1518]	9	hSpCas9	negative selection	4974323
28491492	28491514	16	-	27760321	HT29	viability after 22 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.2519433302391465	[397,310]	[904,756,1270]	9	hSpCas9	negative selection	4974324
28486636	28486658	16	+	27760321	HT29	viability after 22 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4974325
28487519	28487541	16	+	27760321	HT29	viability after 22 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.8589666563064121	[442,345]	[899,714,864]	8	hSpCas9	negative selection	4974326
28488636	28488658	16	+	27760321	HT29	viability after 19 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	1.3649394458978787	[571,446]	[1465,1096,1918]	9	hSpCas9	negative selection	5057785
28489305	28489327	16	+	27760321	HT29	viability after 19 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.7755872418618168	[787,614]	[1390,1056,1661]	7	hSpCas9	negative selection	5057786
28491492	28491514	16	-	27760321	HT29	viability after 19 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.1616354946830885	[397,310]	[806,885,1012]	9	hSpCas9	negative selection	5057787
28486636	28486658	16	+	27760321	HT29	viability after 19 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5057788
28487519	28487541	16	+	27760321	HT29	viability after 19 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.7493292456660333	[442,345]	[869,856,566]	7	hSpCas9	negative selection	5057789
28488636	28488658	16	+	27760321	HT29	viability after 16 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.5637221285350581	[571,446]	[691,822,998]	6	hSpCas9	negative selection	5141248
28489305	28489327	16	+	27760321	HT29	viability after 16 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	1.0203093861023413	[787,614]	[1647,1700,1428]	9	hSpCas9	negative selection	5141249
28491492	28491514	16	-	27760321	HT29	viability after 16 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	1.1392258509433493	[397,310]	[909,692,1025]	9	hSpCas9	negative selection	5141250
28486636	28486658	16	+	27760321	HT29	viability after 16 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	0.20426605822408384	[0,0]	[1,0,0]	2	hSpCas9	negative selection	5141251
28487519	28487541	16	+	27760321	HT29	viability after 16 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.7238755673209343	[442,345]	[609,638,928]	8	hSpCas9	negative selection	5141252
28488636	28488658	16	+	27760321	HT29	viability after 13 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.6523688269949205	[571,446]	[1375,854,576]	8	hSpCas9	negative selection	5224711
28489305	28489327	16	+	27760321	HT29	viability after 13 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.7144738313203187	[787,614]	[1328,1138,1525]	8	hSpCas9	negative selection	5224712
28491492	28491514	16	-	27760321	HT29	viability after 13 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.7040099557958371	[397,310]	[649,554,796]	8	hSpCas9	negative selection	5224713
28486636	28486658	16	+	27760321	HT29	viability after 13 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	2.6784543866600847	[0,0]	[20,0,0]	9	hSpCas9	negative selection	5224714
28487519	28487541	16	+	27760321	HT29	viability after 13 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.448774206722905	[442,345]	[636,630,606]	6	hSpCas9	negative selection	5224715
28488636	28488658	16	+	27760321	HT29	viability after 10 days	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	0.48726542293013	[571,446]	[951,979,748]	6	hSpCas9	negative selection	5308174
28489305	28489327	16	+	27760321	HT29	viability after 10 days	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	0.8089209183064054	[787,614]	[1148,1405,2032]	9	hSpCas9	negative selection	5308175
28491492	28491514	16	-	27760321	HT29	viability after 10 days	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.8624315400611758	[397,310]	[772,734,901]	9	hSpCas9	negative selection	5308176
28486636	28486658	16	+	27760321	HT29	viability after 10 days	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5308177
28487519	28487541	16	+	27760321	HT29	viability after 10 days	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.4976303325741589	[442,345]	[923,807,364]	6	hSpCas9	negative selection	5308178
28488636	28488658	16	+	27760321	MOLM13	viability	GGGGATCGGCGTTGGGCCTGGG	CLN3	ENSG00000188603	1.0733609836611047	[664,571]	[547,888]	7	hSpCas9	negative selection	5391637
28489305	28489327	16	+	27760321	MOLM13	viability	CGATGTCCTCTTGTGGCTAAGG	CLN3	ENSG00000188603	1.1631547383887733	[940,787]	[1276,926]	7	hSpCas9	negative selection	5391638
28491492	28491514	16	-	27760321	MOLM13	viability	GGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.07626791231040017	[537,397]	[364,199]	0	hSpCas9	negative selection	5391639
28486636	28486658	16	+	27760321	MOLM13	viability	TAGCGAAGACCACACCTGGGGG	CLN3	ENSG00000188603	-0.4283021087726899	[3,0]	[0,0]	-3	hSpCas9	negative selection	5391640
28487519	28487541	16	+	27760321	MOLM13	viability	TCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.521974218201135	[527,442]	[165,583]	3	hSpCas9	negative selection	5391641
28491660	28491683	16	+	27661255	K562	viability	GGTGGGCTGCGAGCCAGAGGTGG	CLN3	ENSG00000188603	0.19433018262114798	[1297,1519]	[1376,1204]	6	dCas9-KRAB	negative selection	5471514
28491812	28491835	16	+	27661255	K562	viability	GGCTCCCACGGGAGGGATGAGGG	CLN3	ENSG00000188603	-0.46477140403338546	[498,454]	[302,253]	-7	dCas9-KRAB	negative selection	5471515
28491592	28491615	16	-	27661255	K562	viability	GCGGTCGTGCACCTGAGAGTAGG	CLN3	ENSG00000188603	0.38164910769353133	[193,236]	[250,199]	9	dCas9-KRAB	negative selection	5471516
28491498	28491521	16	+	27260156	BXPC3	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.2281511147895221	[267]	[258,508,234,298]	5	hSpCas9	negative selection	5536231
28482123	28482146	16	-	27260156	BXPC3	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.4520250715437769	[580]	[689,780,850,1040]	8	hSpCas9	negative selection	5536232
28489311	28489334	16	-	27260156	BXPC3	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.004054886127509483	[262]	[240,312,252,297]	0	hSpCas9	negative selection	5536233
28491489	28491512	16	-	27260156	BXPC3	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.30369393134223693	[318]	[324,384,412,548]	6	hSpCas9	negative selection	5600504
28487521	28487544	16	-	27260156	BXPC3	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.16895720431914962	[205]	[243,184,234,314]	4	hSpCas9	negative selection	5600505
28487516	28487539	16	+	27260156	BXPC3	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5053884713024309	[342]	[303,174,269,259]	-8	hSpCas9	negative selection	5600506
28491498	28491521	16	+	27260156	A673	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.28581831743952624	[267]	[304,248,178,331]	-6	hSpCas9	negative selection	5657482
28482123	28482146	16	-	27260156	A673	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.312114052365824	[580]	[874,756,787,1057]	7	hSpCas9	negative selection	5657483
28489311	28489334	16	-	27260156	A673	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.06254006898515241	[262]	[358,323,238,404]	1	hSpCas9	negative selection	5657484
28491489	28491512	16	-	27260156	A673	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.018872069411398518	[318]	[358,370,418,399]	0	hSpCas9	negative selection	5721755
28487521	28487544	16	-	27260156	A673	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.02938882935011189	[205]	[284,249,168,271]	0	hSpCas9	negative selection	5721756
28487516	28487539	16	+	27260156	A673	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.6634297315102161	[342]	[326,225,241,252]	-9	hSpCas9	negative selection	5721757
28491498	28491521	16	+	27260156	A375	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.06145930705380254	[267]	[230,259,441,263]	-1	hSpCas9	negative selection	5778733
28482123	28482146	16	-	27260156	A375	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6069395802915873	[580]	[1013,1207,1247,721]	8	hSpCas9	negative selection	5778734
28489311	28489334	16	-	27260156	A375	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.23737868327493128	[262]	[368,413,259,405]	3	hSpCas9	negative selection	5778735
28491489	28491512	16	-	27260156	A375	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.3450123934464887	[318]	[298,222,351,288]	-5	hSpCas9	negative selection	5843006
28487521	28487544	16	-	27260156	A375	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.12721655406031207	[205]	[292,203,201,183]	-2	hSpCas9	negative selection	5843007
28487516	28487539	16	+	27260156	A375	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.38471282905118165	[342]	[270,242,367,331]	-5	hSpCas9	negative selection	5843008
28491498	28491521	16	+	27260156	COLO741	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.02161006494585682	[267]	[411,324,312]	0	hSpCas9	negative selection	5899984
28482123	28482146	16	-	27260156	COLO741	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.4875518215766397	[580]	[1113,968,1042]	8	hSpCas9	negative selection	5899985
28489311	28489334	16	-	27260156	COLO741	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.27928468822012686	[262]	[382,450,387]	6	hSpCas9	negative selection	5899986
28491489	28491512	16	-	27260156	COLO741	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.0392506661621006	[318]	[521,349,393]	0	hSpCas9	negative selection	5964257
28487521	28487544	16	-	27260156	COLO741	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.18134627177778784	[205]	[268,306,314]	4	hSpCas9	negative selection	5964258
28487516	28487539	16	+	27260156	COLO741	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.6323250519623448	[342]	[291,268,286]	-8	hSpCas9	negative selection	5964259
28491498	28491521	16	+	27260156	CAL120	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.5774117117070526	[267]	[344,193,150]	-7	hSpCas9	negative selection	6021235
28482123	28482146	16	-	27260156	CAL120	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.9096447863302611	[580]	[1826,1151,1168]	9	hSpCas9	negative selection	6021236
28489311	28489334	16	-	27260156	CAL120	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.4288373690552174	[262]	[303,223,210]	-6	hSpCas9	negative selection	6021237
28491489	28491512	16	-	27260156	CAL120	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.7576295664233449	[318]	[378,169,177]	-8	hSpCas9	negative selection	6085508
28487521	28487544	16	-	27260156	CAL120	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.4371472428982188	[205]	[104,135,311]	-6	hSpCas9	negative selection	6085509
28487516	28487539	16	+	27260156	CAL120	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-1.1784173196481276	[342]	[208,184,174]	-9	hSpCas9	negative selection	6085510
28491498	28491521	16	+	27260156	CADOES1	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.1739760960457657	[267]	[234,192,276,176]	-3	hSpCas9	negative selection	6142486
28482123	28482146	16	-	27260156	CADOES1	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.5833783717181348	[580]	[739,684,1041,769]	8	hSpCas9	negative selection	6142487
28489311	28489334	16	-	27260156	CADOES1	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.1792548009828494	[262]	[175,246,231,208]	-3	hSpCas9	negative selection	6142488
28491489	28491512	16	-	27260156	CADOES1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.07395233898673914	[318]	[254,315,187,371]	-1	hSpCas9	negative selection	6206759
28487521	28487544	16	-	27260156	CADOES1	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.17400857591052055	[205]	[325,83,142,123]	-3	hSpCas9	negative selection	6206760
28487516	28487539	16	+	27260156	CADOES1	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.40168986311909916	[342]	[303,254,185,219]	-6	hSpCas9	negative selection	6206761
28491498	28491521	16	+	27260156	EWS502	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.478089245438338	[267]	[174,229,269,137]	-7	hSpCas9	negative selection	6263737
28482123	28482146	16	-	27260156	EWS502	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.8995185272981442	[580]	[1391,1114,1039,999]	9	hSpCas9	negative selection	6263738
28489311	28489334	16	-	27260156	EWS502	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.177545187050123	[262]	[217,222,276,272]	-3	hSpCas9	negative selection	6263739
28491489	28491512	16	-	27260156	EWS502	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.13184572641658804	[318]	[314,215,489,480]	2	hSpCas9	negative selection	6328010
28487521	28487544	16	-	27260156	EWS502	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.3510456925631622	[205]	[233,155,214,534]	6	hSpCas9	negative selection	6328011
28487516	28487539	16	+	27260156	EWS502	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5757005269342289	[342]	[99,203,399,294]	-7	hSpCas9	negative selection	6328012
28491498	28491521	16	+	27260156	EW8	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.1330771989362659	[267]	[173,228,258,116]	-3	hSpCas9	negative selection	6384988
28482123	28482146	16	-	27260156	EW8	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.44374036166245234	[580]	[860,777,410,573]	7	hSpCas9	negative selection	6384989
28489311	28489334	16	-	27260156	EW8	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.20011376705900275	[262]	[185,262,162,133]	-4	hSpCas9	negative selection	6384990
28491489	28491512	16	-	27260156	EW8	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.538449053508293	[318]	[237,125,146,211]	-7	hSpCas9	negative selection	6449261
28487521	28487544	16	-	27260156	EW8	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.15952655089520373	[205]	[152,116,128,201]	-3	hSpCas9	negative selection	6449262
28487516	28487539	16	+	27260156	EW8	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-1.0825305702160204	[342]	[109,157,121,133]	-9	hSpCas9	negative selection	6449263
28491498	28491521	16	+	27260156	CORL105	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.23686288112282805	[267]	[233,357,314,162]	-4	hSpCas9	negative selection	6506239
28482123	28482146	16	-	27260156	CORL105	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.4003872702421085	[580]	[752,859,1093,909]	7	hSpCas9	negative selection	6506240
28489311	28489334	16	-	27260156	CORL105	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.05316932580437639	[262]	[279,234,282,386]	-1	hSpCas9	negative selection	6506241
28491489	28491512	16	-	27260156	CORL105	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.032078933075558314	[318]	[276,337,559,313]	0	hSpCas9	negative selection	6570512
28487521	28487544	16	-	27260156	CORL105	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.19012272997329283	[205]	[165,276,206,191]	-4	hSpCas9	negative selection	6570513
28487516	28487539	16	+	27260156	CORL105	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.6236987461333071	[342]	[206,265,296,275]	-8	hSpCas9	negative selection	6570514
28491498	28491521	16	+	27260156	HS294T	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.4096828850589084	[267]	[64,44,71,142]	-5	hSpCas9	negative selection	6627490
28482123	28482146	16	-	27260156	HS294T	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6726765257980469	[580]	[495,314,270,332]	8	hSpCas9	negative selection	6627491
28489311	28489334	16	-	27260156	HS294T	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.4458873543805052	[262]	[98,95,224,138]	6	hSpCas9	negative selection	6627492
28491489	28491512	16	-	27260156	HS294T	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.6173944470571747	[318]	[269,241,102,119]	7	hSpCas9	negative selection	6691763
28487521	28487544	16	-	27260156	HS294T	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.038805430931130536	[205]	[53,55,89,119]	0	hSpCas9	negative selection	6691764
28487516	28487539	16	+	27260156	HS294T	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.13226866908047652	[342]	[193,105,70,102]	-2	hSpCas9	negative selection	6691765
28491498	28491521	16	+	27260156	HCC44	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.19230737828752142	[267]	[207,158,348,363]	-3	hSpCas9	negative selection	6748741
28482123	28482146	16	-	27260156	HCC44	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.7135699357753574	[580]	[1120,881,1430,963]	9	hSpCas9	negative selection	6748742
28489311	28489334	16	-	27260156	HCC44	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.19594787875792874	[262]	[309,268,225,229]	-3	hSpCas9	negative selection	6748743
28491489	28491512	16	-	27260156	HCC44	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.07694495757628905	[318]	[405,352,434,341]	1	hSpCas9	negative selection	6813014
28487521	28487544	16	-	27260156	HCC44	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.15001021827787464	[205]	[351,145,377,202]	2	hSpCas9	negative selection	6813015
28487516	28487539	16	+	27260156	HCC44	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.34403745189478097	[342]	[243,334,262,358]	-5	hSpCas9	negative selection	6813016
28491498	28491521	16	+	27260156	G402	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.20794474302249533	[267]	[279,410,410,47]	-3	hSpCas9	negative selection	6869992
28482123	28482146	16	-	27260156	G402	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.8503450802441649	[580]	[1370,1225,1622,915]	9	hSpCas9	negative selection	6869993
28489311	28489334	16	-	27260156	G402	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.9045955127910033	[262]	[343,52,238,71]	-8	hSpCas9	negative selection	6869994
28491489	28491512	16	-	27260156	G402	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.33881783485423433	[318]	[199,367,260,384]	-4	hSpCas9	negative selection	6934265
28487521	28487544	16	-	27260156	G402	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.08245538807442299	[205]	[315,110,273,250]	-1	hSpCas9	negative selection	6934266
28487516	28487539	16	+	27260156	G402	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.41407961113076197	[342]	[167,217,241,586]	-5	hSpCas9	negative selection	6934267
28491498	28491521	16	+	27260156	L33	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.20262199461684072	[267]	[317,141,129,360]	4	hSpCas9	negative selection	6991243
28482123	28482146	16	-	27260156	L33	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.29846887067466854	[580]	[629,275,499,760]	6	hSpCas9	negative selection	6991244
28489311	28489334	16	-	27260156	L33	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.08390043401741487	[262]	[250,133,194,227]	1	hSpCas9	negative selection	6991245
28491489	28491512	16	-	27260156	L33	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.1265924419808696	[318]	[362,120,284,281]	3	hSpCas9	negative selection	7055516
28487521	28487544	16	-	27260156	L33	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.0258463704341807	[205]	[185,100,118,187]	0	hSpCas9	negative selection	7055517
28487516	28487539	16	+	27260156	L33	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.36940918643223375	[342]	[290,66,151,363]	-7	hSpCas9	negative selection	7055518
28491498	28491521	16	+	27260156	K562	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.41409338996643597	[267]	[435,86,254,467]	5	hSpCas9	negative selection	7112494
28482123	28482146	16	-	27260156	K562	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.9053739537437507	[580]	[892,1516,960,558]	9	hSpCas9	negative selection	7112495
28489311	28489334	16	-	27260156	K562	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.7246906172980969	[262]	[145,243,150,40]	-7	hSpCas9	negative selection	7112496
28491489	28491512	16	-	27260156	K562	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.2760241513613262	[318]	[151,250,287,236]	-3	hSpCas9	negative selection	7176767
28487521	28487544	16	-	27260156	K562	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.020195635209493856	[205]	[179,72,310,171]	0	hSpCas9	negative selection	7176768
28487516	28487539	16	+	27260156	K562	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	0.16685804993138587	[342]	[330,391,319,325]	2	hSpCas9	negative selection	7176769
28491498	28491521	16	+	27260156	HT29	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.37785650478092225	[267]	[376,167,255,207]	-6	hSpCas9	negative selection	7233745
28482123	28482146	16	-	27260156	HT29	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.3910331272384926	[580]	[801,1031,852,1000]	7	hSpCas9	negative selection	7233746
28489311	28489334	16	-	27260156	HT29	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.2095782045174499	[262]	[369,359,444,307]	4	hSpCas9	negative selection	7233747
28491489	28491512	16	-	27260156	HT29	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.08558712781050326	[318]	[324,346,475,312]	-2	hSpCas9	negative selection	7298018
28487521	28487544	16	-	27260156	HT29	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.03163402331549081	[205]	[193,392,212,231]	0	hSpCas9	negative selection	7298019
28487516	28487539	16	+	27260156	HT29	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.6086389903892929	[342]	[250,383,257,213]	-7	hSpCas9	negative selection	7298020
28491498	28491521	16	+	27260156	MHHES1	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.5818713627322797	[267]	[297,200,132,184]	-8	hSpCas9	negative selection	7354996
28482123	28482146	16	-	27260156	MHHES1	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.7319802019761253	[580]	[1032,1198,1167,957]	9	hSpCas9	negative selection	7354997
28489311	28489334	16	-	27260156	MHHES1	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.42502029540350983	[262]	[416,226,174,108]	-7	hSpCas9	negative selection	7354998
28491489	28491512	16	-	27260156	MHHES1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.09777067437265419	[318]	[467,351,277,269]	-2	hSpCas9	negative selection	7419269
28487521	28487544	16	-	27260156	MHHES1	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.5189778718950611	[205]	[153,199,142,151]	-7	hSpCas9	negative selection	7419270
28487516	28487539	16	+	27260156	MHHES1	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.7253858199698403	[342]	[221,269,168,262]	-8	hSpCas9	negative selection	7419271
28491498	28491521	16	+	27260156	MEWO	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.11865125836425083	[267]	[289,282,246]	2	hSpCas9	negative selection	7476247
28482123	28482146	16	-	27260156	MEWO	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.40943347914353667	[580]	[833,591,761]	8	hSpCas9	negative selection	7476248
28489311	28489334	16	-	27260156	MEWO	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.4725074187080982	[262]	[228,170,141]	-7	hSpCas9	negative selection	7476249
28491489	28491512	16	-	27260156	MEWO	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.22611081023996193	[318]	[396,229,165]	-5	hSpCas9	negative selection	7540520
28487521	28487544	16	-	27260156	MEWO	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.1840666491013221	[205]	[205,154,154]	-4	hSpCas9	negative selection	7540521
28487516	28487539	16	+	27260156	MEWO	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.4750970184509119	[342]	[278,200,221]	-7	hSpCas9	negative selection	7540522
28491498	28491521	16	+	27260156	LNCAPCLONEFGC	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.24670775659422428	[267]	[116,147,394,191]	-4	hSpCas9	negative selection	7597498
28482123	28482146	16	-	27260156	LNCAPCLONEFGC	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.5544201606368412	[580]	[897,714,829,657]	8	hSpCas9	negative selection	7597499
28489311	28489334	16	-	27260156	LNCAPCLONEFGC	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.20910372658746013	[262]	[284,190,269,359]	3	hSpCas9	negative selection	7597500
28491489	28491512	16	-	27260156	LNCAPCLONEFGC	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.297104481703382	[318]	[195,180,329,251]	-5	hSpCas9	negative selection	7661771
28487521	28487544	16	-	27260156	LNCAPCLONEFGC	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.06534657595959303	[205]	[189,212,236,145]	1	hSpCas9	negative selection	7661772
28487516	28487539	16	+	27260156	LNCAPCLONEFGC	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.6808927491002706	[342]	[225,260,179,100]	-7	hSpCas9	negative selection	7661773
28491498	28491521	16	+	27260156	PANC0327	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.8008205406360868	[267]	[158,71,252,72]	-8	hSpCas9	negative selection	7718749
28482123	28482146	16	-	27260156	PANC0327	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6381767226549709	[580]	[1037,894,646,639]	8	hSpCas9	negative selection	7718750
28489311	28489334	16	-	27260156	PANC0327	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.41361811439353446	[262]	[256,506,279,170]	6	hSpCas9	negative selection	7718751
28491489	28491512	16	-	27260156	PANC0327	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.18186214192484917	[318]	[286,212,432,363]	2	hSpCas9	negative selection	7783022
28487521	28487544	16	-	27260156	PANC0327	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.2463686479659084	[205]	[136,69,442,230]	3	hSpCas9	negative selection	7783023
28487516	28487539	16	+	27260156	PANC0327	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.37212479896571304	[342]	[295,161,225,271]	-5	hSpCas9	negative selection	7783024
28491498	28491521	16	+	27260156	NCIH2009	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.17133428233241377	[267]	[373,301,580]	2	hSpCas9	negative selection	7840000
28482123	28482146	16	-	27260156	NCIH2009	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.7498276020416436	[580]	[1643,1304,1199]	9	hSpCas9	negative selection	7840001
28489311	28489334	16	-	27260156	NCIH2009	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.15902711788243373	[262]	[456,429,351]	2	hSpCas9	negative selection	7840002
28491489	28491512	16	-	27260156	NCIH2009	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.2337513266524398	[318]	[617,409,563]	3	hSpCas9	negative selection	7904273
28487521	28487544	16	-	27260156	NCIH2009	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.1542518122201546	[205]	[306,148,330]	-2	hSpCas9	negative selection	7904274
28487516	28487539	16	+	27260156	NCIH2009	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-1.0383051043897038	[342]	[287,255,165]	-8	hSpCas9	negative selection	7904275
28491498	28491521	16	+	27260156	NCIH1373	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.06855126314811821	[267]	[217,261,382,70]	0	hSpCas9	negative selection	7961251
28482123	28482146	16	-	27260156	NCIH1373	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	1.304673799373937	[580]	[2156,1090,1830,387]	9	hSpCas9	negative selection	7961252
28489311	28489334	16	-	27260156	NCIH1373	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.21334944413891843	[262]	[343,59,282,192]	2	hSpCas9	negative selection	7961253
28491489	28491512	16	-	27260156	NCIH1373	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.8831498444990641	[318]	[208,152,122,79]	-7	hSpCas9	negative selection	8025524
28487521	28487544	16	-	27260156	NCIH1373	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.4039506482305518	[205]	[275,174,218,151]	4	hSpCas9	negative selection	8025525
28487516	28487539	16	+	27260156	NCIH1373	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	0.13423794184147486	[342]	[144,491,375,166]	1	hSpCas9	negative selection	8025526
28491498	28491521	16	+	27260156	PATU8902	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.3744624626449897	[267]	[571,426,539,361]	4	hSpCas9	negative selection	8082502
28482123	28482146	16	-	27260156	PATU8902	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.7532025878317404	[580]	[1695,1217,1166,1415]	7	hSpCas9	negative selection	8082503
28489311	28489334	16	-	27260156	PATU8902	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.5301145565534	[262]	[173,479,54,370]	-5	hSpCas9	negative selection	8082504
28491489	28491512	16	-	27260156	PATU8902	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.502455393975889	[318]	[702,863,291,755]	5	hSpCas9	negative selection	8146775
28487521	28487544	16	-	27260156	PATU8902	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.539602659378105	[205]	[197,893,231,389]	5	hSpCas9	negative selection	8146776
28487516	28487539	16	+	27260156	PATU8902	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5291537415447769	[342]	[214,425,177,572]	-5	hSpCas9	negative selection	8146777
28491498	28491521	16	+	27260156	PANC1	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.05915905900674312	[267]	[304,165,243,161]	-1	hSpCas9	negative selection	8203753
28482123	28482146	16	-	27260156	PANC1	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.40064339766833923	[580]	[845,550,714,510]	6	hSpCas9	negative selection	8203754
28489311	28489334	16	-	27260156	PANC1	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.17901370229949964	[262]	[210,402,210,228]	3	hSpCas9	negative selection	8203755
28491489	28491512	16	-	27260156	PANC1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.07455175075961301	[318]	[316,249,379,207]	1	hSpCas9	negative selection	8268026
28487521	28487544	16	-	27260156	PANC1	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.30690351006678807	[205]	[155,197,94,132]	-5	hSpCas9	negative selection	8268027
28487516	28487539	16	+	27260156	PANC1	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.21595151439844618	[342]	[319,192,267,220]	-3	hSpCas9	negative selection	8268028
28491498	28491521	16	+	27260156	PANC0813	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.11039613555584726	[267]	[461,274,311,321]	1	hSpCas9	negative selection	8325004
28482123	28482146	16	-	27260156	PANC0813	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6716996581884701	[580]	[1534,1403,642,818]	9	hSpCas9	negative selection	8325005
28489311	28489334	16	-	27260156	PANC0813	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.04257995374833512	[262]	[379,294,236,362]	0	hSpCas9	negative selection	8325006
28491489	28491512	16	-	27260156	PANC0813	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.26258605941895835	[318]	[464,397,555,383]	4	hSpCas9	negative selection	8389277
28487521	28487544	16	-	27260156	PANC0813	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.0066100112472577965	[205]	[302,311,172,191]	0	hSpCas9	negative selection	8389278
28487516	28487539	16	+	27260156	PANC0813	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.514745156999963	[342]	[380,261,376,125]	-6	hSpCas9	negative selection	8389279
28491498	28491521	16	+	27260156	RDES	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.3195063801307426	[267]	[241,207,252,287]	-5	hSpCas9	negative selection	8446255
28482123	28482146	16	-	27260156	RDES	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6833628351386472	[580]	[1052,990,1106,1125]	9	hSpCas9	negative selection	8446256
28489311	28489334	16	-	27260156	RDES	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.09573027740496742	[262]	[193,418,353,338]	1	hSpCas9	negative selection	8446257
28491489	28491512	16	-	27260156	RDES	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.017726055215121495	[318]	[319,400,357,363]	0	hSpCas9	negative selection	8510528
28487521	28487544	16	-	27260156	RDES	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.17247111801227	[205]	[155,200,290,200]	-3	hSpCas9	negative selection	8510529
28487516	28487539	16	+	27260156	RDES	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.41650671251820437	[342]	[262,213,322,405]	-6	hSpCas9	negative selection	8510530
28491498	28491521	16	+	27260156	PC3	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.17897375570025942	[267]	[144,224,466,213]	-4	hSpCas9	negative selection	8567506
28482123	28482146	16	-	27260156	PC3	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.42791569293014375	[580]	[451,767,1674,637]	8	hSpCas9	negative selection	8567507
28489311	28489334	16	-	27260156	PC3	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.12464743990411686	[262]	[236,280,449,221]	3	hSpCas9	negative selection	8567508
28491489	28491512	16	-	27260156	PC3	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.48866891323599126	[318]	[122,297,314,225]	-8	hSpCas9	negative selection	8631779
28487521	28487544	16	-	27260156	PC3	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.04846485526462119	[205]	[131,168,320,231]	-1	hSpCas9	negative selection	8631780
28487516	28487539	16	+	27260156	PC3	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.7454426574950649	[342]	[128,132,389,255]	-9	hSpCas9	negative selection	8631781
28491498	28491521	16	+	27260156	PATU8988T	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.17189565079779545	[267]	[236,223,356,345]	3	hSpCas9	negative selection	8688757
28482123	28482146	16	-	27260156	PATU8988T	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.34147384866320907	[580]	[684,732,709,719]	6	hSpCas9	negative selection	8688758
28489311	28489334	16	-	27260156	PATU8988T	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.3074457825802104	[262]	[273,287,324,372]	5	hSpCas9	negative selection	8688759
28491489	28491512	16	-	27260156	PATU8988T	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.053474293415601726	[318]	[394,289,363,218]	0	hSpCas9	negative selection	8753030
28487521	28487544	16	-	27260156	PATU8988T	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.2906941612590961	[205]	[124,293,104,137]	-5	hSpCas9	negative selection	8753031
28487516	28487539	16	+	27260156	PATU8988T	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.37642578758163836	[342]	[348,277,229,158]	-6	hSpCas9	negative selection	8753032
28491498	28491521	16	+	27260156	T47D	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.2520915154379121	[267]	[264,220,272,293]	-5	hSpCas9	negative selection	8810008
28482123	28482146	16	-	27260156	T47D	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.507485695208257	[580]	[963,889,967,1034]	9	hSpCas9	negative selection	8810009
28489311	28489334	16	-	27260156	T47D	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.108888747382066	[262]	[309,265,199,365]	-2	hSpCas9	negative selection	8810010
28491489	28491512	16	-	27260156	T47D	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.2755952884214502	[318]	[257,323,331,311]	-6	hSpCas9	negative selection	8874281
28487521	28487544	16	-	27260156	T47D	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.17127914344242745	[205]	[246,219,143,242]	-4	hSpCas9	negative selection	8874282
28487516	28487539	16	+	27260156	T47D	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5992457083150994	[342]	[276,248,251,278]	-8	hSpCas9	negative selection	8874283
28491498	28491521	16	+	27260156	SU8686	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.00588252806400158	[267]	[222,247,302,305]	0	hSpCas9	negative selection	8931259
28482123	28482146	16	-	27260156	SU8686	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6252249380379161	[580]	[669,777,943,1255]	9	hSpCas9	negative selection	8931260
28489311	28489334	16	-	27260156	SU8686	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.08912322948217055	[262]	[287,181,269,397]	1	hSpCas9	negative selection	8931261
28491489	28491512	16	-	27260156	SU8686	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.19707828785140324	[318]	[186,226,378,337]	-3	hSpCas9	negative selection	8995532
28487521	28487544	16	-	27260156	SU8686	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.06820810470292593	[205]	[211,170,182,215]	-1	hSpCas9	negative selection	8995533
28487516	28487539	16	+	27260156	SU8686	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.17495451570613219	[342]	[304,205,190,549]	-3	hSpCas9	negative selection	8995534
28491498	28491521	16	+	27260156	SKES1	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.1654914754603677	[267]	[294,241,257,171]	-4	hSpCas9	negative selection	9052510
28482123	28482146	16	-	27260156	SKES1	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.5911659970176959	[580]	[915,884,970,733]	9	hSpCas9	negative selection	9052511
28489311	28489334	16	-	27260156	SKES1	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.06027443920655673	[262]	[265,304,158,279]	-1	hSpCas9	negative selection	9052512
28491489	28491512	16	-	27260156	SKES1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.03295622864419745	[318]	[384,353,303,273]	0	hSpCas9	negative selection	9116783
28487521	28487544	16	-	27260156	SKES1	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.09881327527035255	[205]	[191,327,138,130]	-2	hSpCas9	negative selection	9116784
28487516	28487539	16	+	27260156	SKES1	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.8667752539368893	[342]	[197,208,179,167]	-9	hSpCas9	negative selection	9116785
28491498	28491521	16	+	27260156	TOV112D	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	0.028040682643400094	[267]	[399,383,71,275]	0	hSpCas9	negative selection	9173761
28482123	28482146	16	-	27260156	TOV112D	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.43398101889275686	[580]	[766,879,851,668]	7	hSpCas9	negative selection	9173762
28489311	28489334	16	-	27260156	TOV112D	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.36175269317455744	[262]	[250,639,292,238]	6	hSpCas9	negative selection	9173763
28491489	28491512	16	-	27260156	TOV112D	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.08478468412061857	[318]	[390,358,163,311]	-2	hSpCas9	negative selection	9238034
28487521	28487544	16	-	27260156	TOV112D	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	0.17584571069484412	[205]	[319,201,192,216]	3	hSpCas9	negative selection	9238035
28487516	28487539	16	+	27260156	TOV112D	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5929055863926126	[342]	[294,247,138,238]	-8	hSpCas9	negative selection	9238036
28491498	28491521	16	+	27260156	TC71	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.27786136911830084	[267]	[264,210,196,277]	-6	hSpCas9	negative selection	9295012
28482123	28482146	16	-	27260156	TC71	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.5157829494598245	[580]	[888,945,683,1059]	9	hSpCas9	negative selection	9295013
28489311	28489334	16	-	27260156	TC71	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.15416829161694434	[262]	[277,173,256,306]	-4	hSpCas9	negative selection	9295014
28491489	28491512	16	-	27260156	TC71	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.3634999882130946	[318]	[261,221,298,279]	-7	hSpCas9	negative selection	9359285
28487521	28487544	16	-	27260156	TC71	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.280787619190638	[205]	[130,174,191,232]	-6	hSpCas9	negative selection	9359286
28487516	28487539	16	+	27260156	TC71	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.620478331334417	[342]	[298,222,281,143]	-9	hSpCas9	negative selection	9359287
28491498	28491521	16	+	27260156	TC32	viability	TCTTCCAATGCGCGCCCTGATGG	CLN3	ENSG00000188603	-0.3898981133515541	[267]	[202,80,318,219]	-6	hSpCas9	negative selection	9416263
28482123	28482146	16	-	27260156	TC32	viability	GCTGTCGCATCCGTTTCACCTGG	CLN3	ENSG00000188603	0.6505877947502556	[580]	[1084,487,946,990]	9	hSpCas9	negative selection	9416264
28489311	28489334	16	-	27260156	TC32	viability	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.09418874552003165	[262]	[298,204,368,197]	1	hSpCas9	negative selection	9416265
28491489	28491512	16	-	27260156	TC32	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.3029858436658006	[318]	[216,193,274,301]	-5	hSpCas9	negative selection	9480536
28487521	28487544	16	-	27260156	TC32	viability	AGCCCCCGGGTTCTCGTCAGTGG	CLN3	ENSG00000188603	-0.2023508265683398	[205]	[255,52,224,171]	-4	hSpCas9	negative selection	9480537
28487516	28487539	16	+	27260156	TC32	viability	AAATCCCACTGACGAGAACCCGG	CLN3	ENSG00000188603	-0.5704061838841888	[342]	[289,96,239,271]	-8	hSpCas9	negative selection	9480538
28486367	28486390	16	+	27869803	HPAFII	viability after 27 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.22303633790187474	[179]	[128,94,NaN]	1	hSpCas9	negative selection	9556439
28486632	28486655	16	+	27869803	HPAFII	viability after 27 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	1.4459738924550447	[335]	[567,408,NaN]	9	hSpCas9	negative selection	9556440
28487519	28487542	16	+	27869803	HPAFII	viability after 27 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.5715466993326783	[142]	[156,73,NaN]	4	hSpCas9	negative selection	9556441
28488652	28488675	16	-	27869803	HPAFII	viability after 27 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-2.38642072474003	[197]	[20,18,NaN]	-8	hSpCas9	negative selection	9556442
28489311	28489334	16	-	27869803	HPAFII	viability after 27 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.5292112823888898	[545]	[91,287,NaN]	-4	hSpCas9	negative selection	9556443
28491492	28491515	16	-	27869803	HPAFII	viability after 27 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.18278693943671742	[473]	[152,274,NaN]	-1	hSpCas9	negative selection	9556444
28486367	28486390	16	+	27869803	HPAFII	viability after 15 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.028858975693176803	[179]	[225,166,NaN]	0	hSpCas9	negative selection	9638888
28486632	28486655	16	+	27869803	HPAFII	viability after 15 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.7338178647280142	[335]	[988,358,NaN]	7	hSpCas9	negative selection	9638889
28487519	28487542	16	+	27869803	HPAFII	viability after 15 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.2045229670068387	[142]	[284,109,NaN]	2	hSpCas9	negative selection	9638890
28488652	28488675	16	-	27869803	HPAFII	viability after 15 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-0.5582288354955252	[197]	[154,137,NaN]	-6	hSpCas9	negative selection	9638891
28489311	28489334	16	-	27869803	HPAFII	viability after 15 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.5202136112360497	[545]	[328,458,NaN]	-5	hSpCas9	negative selection	9638892
28491492	28491515	16	-	27869803	HPAFII	viability after 15 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.10186247581166274	[473]	[589,402,NaN]	-1	hSpCas9	negative selection	9638893
28486367	28486390	16	+	27869803	ASPC1	viability after 36 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.37632089442397987	[372]	[85,174,49]	-4	hSpCas9	negative selection	9721337
28486632	28486655	16	+	27869803	ASPC1	viability after 36 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.35821659713189247	[663]	[422,205,277]	3	hSpCas9	negative selection	9721338
28487519	28487542	16	+	27869803	ASPC1	viability after 36 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-1.2896260018312433	[328]	[24,32,72]	-8	hSpCas9	negative selection	9721339
28488652	28488675	16	-	27869803	ASPC1	viability after 36 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	0.5215493777950891	[427]	[486,182,45]	5	hSpCas9	negative selection	9721340
28489311	28489334	16	-	27869803	ASPC1	viability after 36 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.5666591963745575	[1402]	[410,1022,701]	5	hSpCas9	negative selection	9721341
28491492	28491515	16	-	27869803	ASPC1	viability after 36 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.6481762757370803	[1042]	[476,551,644]	6	hSpCas9	negative selection	9721342
28486367	28486390	16	+	27869803	PATU8988S	viability after 35 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.999200685043983	[337]	[112,22,NaN]	-7	hSpCas9	negative selection	9803786
28486632	28486655	16	+	27869803	PATU8988S	viability after 35 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.520367479584873	[624]	[380,340,NaN]	6	hSpCas9	negative selection	9803787
28487519	28487542	16	+	27869803	PATU8988S	viability after 35 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.4250438437122618	[421]	[311,143,NaN]	5	hSpCas9	negative selection	9803788
28488652	28488675	16	-	27869803	PATU8988S	viability after 35 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-0.432541356126937	[471]	[76,204,NaN]	-4	hSpCas9	negative selection	9803789
28489311	28489334	16	-	27869803	PATU8988S	viability after 35 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	0.10889434225527661	[1396]	[498,714,NaN]	1	hSpCas9	negative selection	9803790
28491492	28491515	16	-	27869803	PATU8988S	viability after 35 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.9355884065865281	[774]	[598,594,NaN]	8	hSpCas9	negative selection	9803791
28486367	28486390	16	+	27869803	PATU8988S	viability after 31 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.4654220129610833	[337]	[156,21,NaN]	-5	hSpCas9	negative selection	9886235
28486632	28486655	16	+	27869803	PATU8988S	viability after 31 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	0.3288886241903609	[624]	[239,405,NaN]	4	hSpCas9	negative selection	9886236
28487519	28487542	16	+	27869803	PATU8988S	viability after 31 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	-0.06688842705561804	[421]	[190,121,NaN]	0	hSpCas9	negative selection	9886237
28488652	28488675	16	-	27869803	PATU8988S	viability after 31 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-0.2895380256684298	[471]	[76,251,NaN]	-3	hSpCas9	negative selection	9886238
28489311	28489334	16	-	27869803	PATU8988S	viability after 31 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.402256412337749	[1396]	[329,537,NaN]	-4	hSpCas9	negative selection	9886239
28491492	28491515	16	-	27869803	PATU8988S	viability after 31 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	0.5364339670012033	[774]	[478,408,NaN]	6	hSpCas9	negative selection	9886240
28486367	28486390	16	+	27869803	HPAFII	viability after 35 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	0.07448498725212932	[179]	[118,69,NaN]	0	hSpCas9	negative selection	9968684
28486632	28486655	16	+	27869803	HPAFII	viability after 35 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	1.2958746529585414	[335]	[514,307,NaN]	8	hSpCas9	negative selection	9968685
28487519	28487542	16	+	27869803	HPAFII	viability after 35 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.4513434198404856	[142]	[66,134,NaN]	3	hSpCas9	negative selection	9968686
28488652	28488675	16	-	27869803	HPAFII	viability after 35 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-3.2039968870751467	[197]	[0,21,NaN]	-8	hSpCas9	negative selection	9968687
28489311	28489334	16	-	27869803	HPAFII	viability after 35 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.4135224448543162	[545]	[80,349,NaN]	-3	hSpCas9	negative selection	9968688
28491492	28491515	16	-	27869803	HPAFII	viability after 35 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.24300518819856798	[473]	[79,340,NaN]	-1	hSpCas9	negative selection	9968689
28486367	28486390	16	+	27869803	HPAFII	viability after 31 days	GATACCCAGCATGGACAGCAGGG	CLN3	ENSG00000188603	-0.17581797177940278	[179]	[98,78,NaN]	-1	hSpCas9	negative selection	10051133
28486632	28486655	16	+	27869803	HPAFII	viability after 31 days	ATGCTAGCGAAGACCACACCTGG	CLN3	ENSG00000188603	1.6414795193290685	[335]	[717,446,NaN]	9	hSpCas9	negative selection	10051134
28487519	28487542	16	+	27869803	HPAFII	viability after 31 days	TCCCACTGACGAGAACCCGGGGG	CLN3	ENSG00000188603	0.48801366555069137	[142]	[124,98,NaN]	3	hSpCas9	negative selection	10051135
28488652	28488675	16	-	27869803	HPAFII	viability after 31 days	TTCTCCCATTAGGTGGACCCAGG	CLN3	ENSG00000188603	-2.1952229344701175	[197]	[18,29,NaN]	-8	hSpCas9	negative selection	10051136
28489311	28489334	16	-	27869803	HPAFII	viability after 31 days	ACGACATCCTTAGCCACAAGAGG	CLN3	ENSG00000188603	-0.08438894587269763	[545]	[132,458,NaN]	0	hSpCas9	negative selection	10051137
28491492	28491515	16	-	27869803	HPAFII	viability after 31 days	GGGCGCGCATTGGAAGAACGCGG	CLN3	ENSG00000188603	-0.14899679387389675	[473]	[170,314,NaN]	-1	hSpCas9	negative selection	10051138
28491733	28491756	16	-	28162770	P31FUJ	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.5831147311466494	[95]	[168]	6	hSpCas9	negative selection	10134755
28487518	28487541	16	+	28162770	P31FUJ	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.513570843007526	[213]	[358]	6	hSpCas9	negative selection	10134756
28484024	28484047	16	-	28162770	P31FUJ	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.49356827451262864	[245]	[406]	5	hSpCas9	negative selection	10134757
28482144	28482167	16	+	28162770	P31FUJ	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-0.8525301232962113	[62]	[40]	-6	hSpCas9	negative selection	10134758
28491489	28491512	16	-	28162770	P31FUJ	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.31468559088811476	[25]	[37]	3	hSpCas9	negative selection	10134759
28482326	28482349	16	-	28162770	P31FUJ	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.11448223722561728	[233]	[253]	-1	hSpCas9	negative selection	10134760
28477796	28477819	16	+	28162770	P31FUJ	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.1953935167437508	[190]	[256]	2	hSpCas9	negative selection	10134761
28477749	28477772	16	+	28162770	P31FUJ	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.4226267632943956	[72]	[31]	-7	hSpCas9	negative selection	10134762
28491518	28491541	16	+	28162770	P31FUJ	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.8826750130055574	[77]	[168]	8	hSpCas9	negative selection	10134763
28487699	28487722	16	+	28162770	P31FUJ	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.1167462132762056	[506]	[645]	1	hSpCas9	negative selection	10134764
28491733	28491756	16	-	28162770	TF1	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10304121
28487518	28487541	16	+	28162770	TF1	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10304122
28484024	28484047	16	-	28162770	TF1	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10304123
28482144	28482167	16	+	28162770	TF1	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10304124
28491489	28491512	16	-	28162770	TF1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10304125
28482326	28482349	16	-	28162770	TF1	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10304126
28477796	28477819	16	+	28162770	TF1	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10304127
28477749	28477772	16	+	28162770	TF1	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10304128
28491518	28491541	16	+	28162770	TF1	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10304129
28487699	28487722	16	+	28162770	TF1	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	NaN	[NaN]	[400]	1	hSpCas9	negative selection	10304130
28491733	28491756	16	-	28162770	SKM1	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-1.0146467759644013	[31]	[27]	-6	hSpCas9	negative selection	10473487
28487518	28487541	16	+	28162770	SKM1	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	1.2752955033329094	[42]	[183]	9	hSpCas9	negative selection	10473488
28484024	28484047	16	-	28162770	SKM1	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.9444857045470005	[85]	[78]	-6	hSpCas9	negative selection	10473489
28482144	28482167	16	+	28162770	SKM1	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-5.5224414161630975	[25]	[0]	-9	hSpCas9	negative selection	10473490
28491489	28491512	16	-	28162770	SKM1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10473491
28482326	28482349	16	-	28162770	SKM1	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.0514835441447728	[50]	[86]	0	hSpCas9	negative selection	10473492
28477796	28477819	16	+	28162770	SKM1	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	-0.1975108331142117	[23]	[36]	-2	hSpCas9	negative selection	10473493
28477749	28477772	16	+	28162770	SKM1	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.2370391973008492	[15]	[11]	-7	hSpCas9	negative selection	10473494
28491518	28491541	16	+	28162770	SKM1	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.3155018257279294	[19]	[43]	3	hSpCas9	negative selection	10473495
28487699	28487722	16	+	28162770	SKM1	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	1.2178910291015073	[106]	[439]	9	hSpCas9	negative selection	10473496
28491733	28491756	16	-	28162770	SKM1	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-1.0146467759644013	[31]	[27]	-6	hSpCas9	negative selection	10642853
28487518	28487541	16	+	28162770	SKM1	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	1.2752955033329094	[42]	[183]	9	hSpCas9	negative selection	10642854
28484024	28484047	16	-	28162770	SKM1	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.9444857045470005	[85]	[78]	-6	hSpCas9	negative selection	10642855
28482144	28482167	16	+	28162770	SKM1	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-5.5224414161630975	[25]	[0]	-9	hSpCas9	negative selection	10642856
28491489	28491512	16	-	28162770	SKM1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10642857
28482326	28482349	16	-	28162770	SKM1	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.0514835441447728	[50]	[86]	0	hSpCas9	negative selection	10642858
28477796	28477819	16	+	28162770	SKM1	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	-0.1975108331142117	[23]	[36]	-2	hSpCas9	negative selection	10642859
28477749	28477772	16	+	28162770	SKM1	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.2370391973008492	[15]	[11]	-7	hSpCas9	negative selection	10642860
28491518	28491541	16	+	28162770	SKM1	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.3155018257279294	[19]	[43]	3	hSpCas9	negative selection	10642861
28487699	28487722	16	+	28162770	SKM1	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	1.2178910291015073	[106]	[439]	9	hSpCas9	negative selection	10642862
28491733	28491756	16	-	28162770	PL21	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.7503366970497998	[55]	[40]	6	hSpCas9	negative selection	10812219
28487518	28487541	16	+	28162770	PL21	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.11020050612283028	[123]	[49]	-1	hSpCas9	negative selection	10812220
28484024	28484047	16	-	28162770	PL21	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.34155936907654283	[300]	[165]	3	hSpCas9	negative selection	10812221
28482144	28482167	16	+	28162770	PL21	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-4.209251321648382	[84]	[1]	-9	hSpCas9	negative selection	10812222
28491489	28491512	16	-	28162770	PL21	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-2.2592920041479774	[21]	[1]	-8	hSpCas9	negative selection	10812223
28482326	28482349	16	-	28162770	PL21	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	0.4735906362684522	[229]	[138]	4	hSpCas9	negative selection	10812224
28477796	28477819	16	+	28162770	PL21	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.2578551123456073	[97]	[50]	2	hSpCas9	negative selection	10812225
28477749	28477772	16	+	28162770	PL21	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-2.5277808400738793	[52]	[3]	-9	hSpCas9	negative selection	10812226
28491518	28491541	16	+	28162770	PL21	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	1.7147127873190784	[48]	[69]	9	hSpCas9	negative selection	10812227
28487699	28487722	16	+	28162770	PL21	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.18355673029371578	[349]	[172]	1	hSpCas9	negative selection	10812228
28491733	28491756	16	-	28162770	P31FUJ	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.5831147311466494	[95]	[168]	6	hSpCas9	negative selection	10981585
28487518	28487541	16	+	28162770	P31FUJ	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.513570843007526	[213]	[358]	6	hSpCas9	negative selection	10981586
28484024	28484047	16	-	28162770	P31FUJ	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.49356827451262864	[245]	[406]	5	hSpCas9	negative selection	10981587
28482144	28482167	16	+	28162770	P31FUJ	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-0.8525301232962113	[62]	[40]	-6	hSpCas9	negative selection	10981588
28491489	28491512	16	-	28162770	P31FUJ	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.31468559088811476	[25]	[37]	3	hSpCas9	negative selection	10981589
28482326	28482349	16	-	28162770	P31FUJ	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.11448223722561728	[233]	[253]	-1	hSpCas9	negative selection	10981590
28477796	28477819	16	+	28162770	P31FUJ	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.1953935167437508	[190]	[256]	2	hSpCas9	negative selection	10981591
28477749	28477772	16	+	28162770	P31FUJ	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.4226267632943956	[72]	[31]	-7	hSpCas9	negative selection	10981592
28491518	28491541	16	+	28162770	P31FUJ	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.8826750130055574	[77]	[168]	8	hSpCas9	negative selection	10981593
28487699	28487722	16	+	28162770	P31FUJ	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.1167462132762056	[506]	[645]	1	hSpCas9	negative selection	10981594
28491733	28491756	16	-	28162770	OCIAML5	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-1.5647846187835257	[58]	[35]	-7	hSpCas9	negative selection	11150951
28487518	28487541	16	+	28162770	OCIAML5	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.28298338929985567	[106]	[234]	2	hSpCas9	negative selection	11150952
28484024	28484047	16	-	28162770	OCIAML5	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.5023641637106949	[157]	[403]	4	hSpCas9	negative selection	11150953
28482144	28482167	16	+	28162770	OCIAML5	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-1.0271532774220882	[34]	[30]	-6	hSpCas9	negative selection	11150954
28491489	28491512	16	-	28162770	OCIAML5	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	-3.852066570863997	[15]	[1]	-9	hSpCas9	negative selection	11150955
28482326	28482349	16	-	28162770	OCIAML5	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	0.7990862095516258	[70]	[222]	7	hSpCas9	negative selection	11150956
28477796	28477819	16	+	28162770	OCIAML5	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.29645595384609114	[82]	[183]	2	hSpCas9	negative selection	11150957
28477749	28477772	16	+	28162770	OCIAML5	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	0.4317263951365944	[22]	[55]	4	hSpCas9	negative selection	11150958
28491518	28491541	16	+	28162770	OCIAML5	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.23282232672251624	[32]	[69]	2	hSpCas9	negative selection	11150959
28487699	28487722	16	+	28162770	OCIAML5	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.6441670112628277	[189]	[535]	5	hSpCas9	negative selection	11150960
28491733	28491756	16	-	28162770	EOL1	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	1.1030859033175549	[166]	[188]	8	hSpCas9	negative selection	11320317
28487518	28487541	16	+	28162770	EOL1	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.12292921906207505	[250]	[143]	1	hSpCas9	negative selection	11320318
28484024	28484047	16	-	28162770	EOL1	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.3756443936655332	[526]	[213]	-3	hSpCas9	negative selection	11320319
28482144	28482167	16	+	28162770	EOL1	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-5.9580952777913065	[117]	[0]	-9	hSpCas9	negative selection	11320320
28491489	28491512	16	-	28162770	EOL1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	2.0500786536543933	[21]	[47]	9	hSpCas9	negative selection	11320321
28482326	28482349	16	-	28162770	EOL1	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.017659653236929473	[366]	[190]	0	hSpCas9	negative selection	11320322
28477796	28477819	16	+	28162770	EOL1	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.913900527371026	[135]	[134]	7	hSpCas9	negative selection	11320323
28477749	28477772	16	+	28162770	EOL1	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.4904897277083093	[63]	[11]	-7	hSpCas9	negative selection	11320324
28491518	28491541	16	+	28162770	EOL1	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.6604147291506215	[62]	[20]	-5	hSpCas9	negative selection	11320325
28487699	28487722	16	+	28162770	EOL1	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.3210038451076528	[546]	[359]	3	hSpCas9	negative selection	11320326
28491733	28491756	16	-	28162770	MOLM13	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	1.715816894988164	[95]	[227]	9	hSpCas9	negative selection	11489683
28487518	28487541	16	+	28162770	MOLM13	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.49244648578855776	[232]	[236]	3	hSpCas9	negative selection	11489684
28484024	28484047	16	-	28162770	MOLM13	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	1.0157625635305148	[393]	[575]	7	hSpCas9	negative selection	11489685
28482144	28482167	16	+	28162770	MOLM13	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-4.561857961849473	[97]	[2]	-9	hSpCas9	negative selection	11489686
28491489	28491512	16	-	28162770	MOLM13	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.19658735972718455	[34]	[28]	1	hSpCas9	negative selection	11489687
28482326	28482349	16	-	28162770	MOLM13	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.7571771740901945	[359]	[153]	-4	hSpCas9	negative selection	11489688
28477796	28477819	16	+	28162770	MOLM13	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.9051568282068883	[160]	[217]	7	hSpCas9	negative selection	11489689
28477749	28477772	16	+	28162770	MOLM13	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-1.0309164754268627	[64]	[22]	-5	hSpCas9	negative selection	11489690
28491518	28491541	16	+	28162770	MOLM13	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.4166334010354853	[47]	[25]	-2	hSpCas9	negative selection	11489691
28487699	28487722	16	+	28162770	MOLM13	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.6414256365392701	[531]	[599]	5	hSpCas9	negative selection	11489692
28491733	28491756	16	-	28162770	HEL	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.43905525916329047	[126]	[59]	-3	hSpCas9	negative selection	11659049
28487518	28487541	16	+	28162770	HEL	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-1.2971401755620722	[187]	[48]	-6	hSpCas9	negative selection	11659050
28484024	28484047	16	-	28162770	HEL	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	-0.07647809317136323	[376]	[228]	0	hSpCas9	negative selection	11659051
28482144	28482167	16	+	28162770	HEL	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-2.5271861694419555	[98]	[10]	-8	hSpCas9	negative selection	11659052
28491489	28491512	16	-	28162770	HEL	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.753770144389101	[24]	[26]	6	hSpCas9	negative selection	11659053
28482326	28482349	16	-	28162770	HEL	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.09794505041195951	[258]	[154]	0	hSpCas9	negative selection	11659054
28477796	28477819	16	+	28162770	HEL	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.7329366409719351	[123]	[131]	6	hSpCas9	negative selection	11659055
28477749	28477772	16	+	28162770	HEL	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-4.215242163127215	[57]	[1]	-9	hSpCas9	negative selection	11659056
28491518	28491541	16	+	28162770	HEL	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-2.500219121841686	[52]	[5]	-8	hSpCas9	negative selection	11659057
28487699	28487722	16	+	28162770	HEL	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.09417056853960026	[410]	[280]	0	hSpCas9	negative selection	11659058
28491733	28491756	16	-	28162770	MV411	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.4896384531994035	[92]	[109]	4	hSpCas9	negative selection	11828415
28487518	28487541	16	+	28162770	MV411	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.8131039911522755	[145]	[69]	-5	hSpCas9	negative selection	11828416
28484024	28484047	16	-	28162770	MV411	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.5559272713453333	[301]	[373]	5	hSpCas9	negative selection	11828417
28482144	28482167	16	+	28162770	MV411	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-2.9541963103868754	[91]	[9]	-9	hSpCas9	negative selection	11828418
28491489	28491512	16	-	28162770	MV411	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.5522921323111962	[16]	[20]	5	hSpCas9	negative selection	11828419
28482326	28482349	16	-	28162770	MV411	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.45396685816048604	[186]	[114]	-3	hSpCas9	negative selection	11828420
28477796	28477819	16	+	28162770	MV411	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	-0.13845360283655206	[97]	[74]	-1	hSpCas9	negative selection	11828421
28477749	28477772	16	+	28162770	MV411	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-0.14487987199598473	[41]	[31]	-1	hSpCas9	negative selection	11828422
28491518	28491541	16	+	28162770	MV411	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.4046391457969176	[43]	[27]	-3	hSpCas9	negative selection	11828423
28487699	28487722	16	+	28162770	MV411	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	1.0061918337142681	[275]	[466]	8	hSpCas9	negative selection	11828424
28491733	28491756	16	-	28162770	MONOMAC1	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-1.1299226512010168	[62]	[32]	-7	hSpCas9	negative selection	11997781
28487518	28487541	16	+	28162770	MONOMAC1	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.19454167939530126	[92]	[121]	2	hSpCas9	negative selection	11997782
28484024	28484047	16	-	28162770	MONOMAC1	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.354867365082307	[205]	[301]	3	hSpCas9	negative selection	11997783
28482144	28482167	16	+	28162770	MONOMAC1	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-1.2180984625873834	[68]	[33]	-7	hSpCas9	negative selection	11997784
28491489	28491512	16	-	28162770	MONOMAC1	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.3879256536616027	[5]	[8]	4	hSpCas9	negative selection	11997785
28482326	28482349	16	-	28162770	MONOMAC1	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.13290650963983808	[109]	[114]	-1	hSpCas9	negative selection	11997786
28477796	28477819	16	+	28162770	MONOMAC1	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	1.0768858749169765	[54]	[132]	8	hSpCas9	negative selection	11997787
28477749	28477772	16	+	28162770	MONOMAC1	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	0.03428869904690224	[22]	[26]	0	hSpCas9	negative selection	11997788
28491518	28491541	16	+	28162770	MONOMAC1	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.00941403040787292	[38]	[44]	0	hSpCas9	negative selection	11997789
28487699	28487722	16	+	28162770	MONOMAC1	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.6093935667697523	[222]	[389]	6	hSpCas9	negative selection	11997790
28491733	28491756	16	-	28162770	OCIAML2	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	0.28739738445187457	[16]	[114]	2	hSpCas9	negative selection	12167147
28487518	28487541	16	+	28162770	OCIAML2	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	0.1750867065580913	[30]	[193]	1	hSpCas9	negative selection	12167148
28484024	28484047	16	-	28162770	OCIAML2	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.1635761944988443	[47]	[297]	1	hSpCas9	negative selection	12167149
28482144	28482167	16	+	28162770	OCIAML2	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-6.640554826684474	[17]	[0]	-9	hSpCas9	negative selection	12167150
28491489	28491512	16	-	28162770	OCIAML2	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.5737642941162922	[7]	[65]	5	hSpCas9	negative selection	12167151
28482326	28482349	16	-	28162770	OCIAML2	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.5996162659622392	[37]	[138]	-4	hSpCas9	negative selection	12167152
28477796	28477819	16	+	28162770	OCIAML2	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.22326704703215894	[16]	[109]	2	hSpCas9	negative selection	12167153
28477749	28477772	16	+	28162770	OCIAML2	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-0.523097245136297	[6]	[26]	-4	hSpCas9	negative selection	12167154
28491518	28491541	16	+	28162770	OCIAML2	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	-0.8267736354674367	[7]	[24]	-5	hSpCas9	negative selection	12167155
28487699	28487722	16	+	28162770	OCIAML2	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	0.8276192731756904	[42]	[422]	7	hSpCas9	negative selection	12167156
28491733	28491756	16	-	28162770	OCIAML3	viability	GAGGCTGTGCAGGCTCGCGGCGG	CLN3	ENSG00000188603	-0.1633732859943009	[22]	[61]	-1	hSpCas9	negative selection	12336513
28487518	28487541	16	+	28162770	OCIAML3	viability	ATCCCACTGACGAGAACCCGGGG	CLN3	ENSG00000188603	-0.24485807670177667	[41]	[106]	-2	hSpCas9	negative selection	12336514
28484024	28484047	16	-	28162770	OCIAML3	viability	GCAGCCCCTCATAAGAACCGAGG	CLN3	ENSG00000188603	0.34294018914053537	[75]	[290]	3	hSpCas9	negative selection	12336515
28482144	28482167	16	+	28162770	OCIAML3	viability	GCAGCGGAGAGAAGAGCGGGAGG	CLN3	ENSG00000188603	-0.2154960170704332	[14]	[38]	-2	hSpCas9	negative selection	12336516
28491489	28491512	16	-	28162770	OCIAML3	viability	CGCGCATTGGAAGAACGCGGTGG	CLN3	ENSG00000188603	0.8654239783131343	[7]	[43]	7	hSpCas9	negative selection	12336517
28482326	28482349	16	-	28162770	OCIAML3	viability	GTCACGCTCAGCAATACCGCTGG	CLN3	ENSG00000188603	-0.276817464443464	[60]	[151]	-2	hSpCas9	negative selection	12336518
28477796	28477819	16	+	28162770	OCIAML3	viability	ACAGAATGATCAGGAAGACGAGG	CLN3	ENSG00000188603	0.16272120866347306	[28]	[97]	1	hSpCas9	negative selection	12336519
28477749	28477772	16	+	28162770	OCIAML3	viability	GTTGTGGAAGGTGTTCACGTAGG	CLN3	ENSG00000188603	-2.2314375609394546	[13]	[8]	-8	hSpCas9	negative selection	12336520
28491518	28491541	16	+	28162770	OCIAML3	viability	TGGTCCAACAGAGGGAGCCGGGG	CLN3	ENSG00000188603	0.8389517669519428	[9]	[53]	7	hSpCas9	negative selection	12336521
28487699	28487722	16	+	28162770	OCIAML3	viability	ATTTGATGACGAGTGTGGGGAGG	CLN3	ENSG00000188603	1.0062216170503036	[93]	[569]	8	hSpCas9	negative selection	12336522