Gene2Function

Crispr

Gene Info

Species: Human (Homo sapiens)
GeneID: 65260
Symbol: COA7
Description: cytochrome c oxidase assembly factor 7

DataSource: http://genomecrispr.dkfz.de/#!/results/COA7

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52693315	52693338	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTGGG	COA7	ENSG00000162377	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446346
52693315	52693338	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTGGG	COA7	ENSG00000162377	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541601
52688120	52688143	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	-1.1034483233513073	[3,4]	[1,0]	-9	hSpCas9	positive selection	2980308
52698228	52698251	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	0.02717198909307042	[4,4]	[7,0]	0	hSpCas9	positive selection	2980309
52698220	52698243	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	-1.782012302804811	[3,4]	[0,0]	-9	hSpCas9	positive selection	2980310
52692748	52692771	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	-0.01984457297998347	[3,3]	[2,3]	0	hSpCas9	positive selection	2980311
52688120	52688143	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	-0.5349701197751738	[3,3]	[3,0]	-7	hSpCas9	positive selection	3048166
52698228	52698251	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	-0.05952234919984534	[4,4]	[4,1]	-1	hSpCas9	positive selection	3048167
52698220	52698243	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	-0.974736646580714	[3,3]	[1,0]	-9	hSpCas9	positive selection	3048168
52692748	52692771	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	-0.1319142014457952	[3,3]	[0,2]	-2	hSpCas9	positive selection	3048169
52688119	52688142	1	+	26780180	HT29	viability (Avana library 4 designs)	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	2.83046224770229	[]	[]	8	hSpCas9	negative selection	3416757
52698227	52698250	1	+	26780180	HT29	viability (Avana library 4 designs)	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	3.33390641750218	[]	[]	8	hSpCas9	negative selection	3416758
52698220	52698243	1	-	26780180	HT29	viability (Avana library 4 designs)	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	4.98279510402197	[]	[]	9	hSpCas9	negative selection	3416759
52692748	52692771	1	-	26780180	HT29	viability (Avana library 4 designs)	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	4.23964812638091	[]	[]	9	hSpCas9	negative selection	3416760
52698227	52698250	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	-0.832764096113794	[]	[]	-1	hSpCas9	negative selection	3494439
52688119	52688142	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	-5.35163843739544	[]	[]	-5	hSpCas9	negative selection	3494440
52698220	52698243	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	-12.1827822967222	[]	[]	-8	hSpCas9	negative selection	3494441
52692748	52692771	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	-6.00171382443279	[]	[]	-6	hSpCas9	negative selection	3494442
52688072	52688095	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-3.70971461748974	[]	[]	-4	hSpCas9	negative selection	3494443
52688134	52688157	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGACCTGAAAGCTGCCGCCAGG	COA7	ENSG00000162377	-0.0990385603935556	[]	[]	0	hSpCas9	negative selection	3494444
52698227	52698250	1	+	26780180	A375	viability (Avana lentiGuide)	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	12.4810730364333	[]	[]	7	hSpCas9	negative selection	3603098
52688119	52688142	1	+	26780180	A375	viability (Avana lentiGuide)	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	11.1216862856755	[]	[]	7	hSpCas9	negative selection	3603099
52698220	52698243	1	-	26780180	A375	viability (Avana lentiGuide)	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	39.3401024862319	[]	[]	9	hSpCas9	negative selection	3603100
52692748	52692771	1	-	26780180	A375	viability (Avana lentiGuide)	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	12.3013985779231	[]	[]	7	hSpCas9	negative selection	3603101
52688072	52688095	1	-	26780180	A375	viability (Avana lentiGuide)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	22.9947714829177	[]	[]	9	hSpCas9	negative selection	3603102
52688134	52688157	1	-	26780180	A375	viability (Avana lentiGuide)	AGGACCTGAAAGCTGCCGCCAGG	COA7	ENSG00000162377	7.58326453859865	[]	[]	6	hSpCas9	negative selection	3603103
52698227	52698250	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	0.17093773482874972	[5]	[6,6]	4	hSpCas9	positive selection	3711757
52688119	52688142	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	-0.119524935815384	[5]	[6,3]	-2	hSpCas9	positive selection	3711758
52698220	52698243	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	0.08663489639283861	[5]	[6,5]	2	hSpCas9	positive selection	3711759
52692748	52692771	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	-0.009692361300197894	[5]	[4,4]	0	hSpCas9	positive selection	3711760
52688072	52688095	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	0.1379461874737522	[5]	[5,5]	3	hSpCas9	positive selection	3711761
52688134	52688157	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGACCTGAAAGCTGCCGCCAGG	COA7	ENSG00000162377	0.1633397095027248	[4]	[4,4]	4	hSpCas9	positive selection	3711762
52698227	52698250	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCTTCTCGTGGTAGCAGTGG	COA7	ENSG00000162377	0.2730623015444176	[6]	[6,6]	7	hSpCas9	positive selection	3820364
52688119	52688142	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCCATCAAAAAGCACCTGGCGG	COA7	ENSG00000162377	0.18870900178128486	[6]	[6,5]	4	hSpCas9	positive selection	3820365
52698220	52698243	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACCACGAGAAGGACCCGGACGG	COA7	ENSG00000162377	0.1506033746264462	[6]	[5,6]	3	hSpCas9	positive selection	3820366
52692748	52692771	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATAGCTGCTACAAACTGGGGG	COA7	ENSG00000162377	0.14236041957410003	[5]	[5,4]	3	hSpCas9	positive selection	3820367
52688072	52688095	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.02933078258043373	[6]	[5,4]	0	hSpCas9	positive selection	3820368
52688134	52688157	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGACCTGAAAGCTGCCGCCAGG	COA7	ENSG00000162377	0.35028568238936736	[5]	[6,5]	9	hSpCas9	positive selection	3820369
52688072	52688095	1	-	26780180	A375	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	1.83187028583673	[]	[]	9	hSpCas9	negative selection	3928357
52698218	52698241	1	+	26780180	A375	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	1.98684722143759	[]	[]	9	hSpCas9	negative selection	3928358
52687825	52687848	1	+	26780180	A375	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	1.07301597708058	[]	[]	5	hSpCas9	negative selection	3928359
52698314	52698337	1	-	26780180	A375	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	1.40050296240471	[]	[]	7	hSpCas9	negative selection	3928360
52692853	52692876	1	-	26780180	A375	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	1.92765330811295	[]	[]	9	hSpCas9	negative selection	3928361
52692830	52692853	1	-	26780180	A375	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	1.81949932837039	[]	[]	9	hSpCas9	negative selection	3928362
52688072	52688095	1	-	26780180	HT29	viability (GeCKOv2 library)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	2.04912043660327	[]	[]	9	hSpCas9	negative selection	4036323
52698218	52698241	1	+	26780180	HT29	viability (GeCKOv2 library)	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	1.8041966455741	[]	[]	8	hSpCas9	negative selection	4036324
52687825	52687848	1	+	26780180	HT29	viability (GeCKOv2 library)	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	1.09838720009961	[]	[]	5	hSpCas9	negative selection	4036325
52698314	52698337	1	-	26780180	HT29	viability (GeCKOv2 library)	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	1.02690092525251	[]	[]	5	hSpCas9	negative selection	4036326
52692853	52692876	1	-	26780180	HT29	viability (GeCKOv2 library)	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	1.99325575509822	[]	[]	9	hSpCas9	negative selection	4036327
52692830	52692853	1	-	26780180	HT29	viability (GeCKOv2 library)	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	2.29608525871437	[]	[]	9	hSpCas9	negative selection	4036328
52698218	52698241	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.0981875227528301	[3]	[2,2]	2	hSpCas9	positive selection	4169102
52698314	52698337	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.3142816620731055	[1]	[0,0]	-6	hSpCas9	positive selection	4169103
52692830	52692853	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.20643922833638997	[3]	[1,1]	-5	hSpCas9	positive selection	4169105
52698218	52698241	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.04104738204615551	[3]	[1,2,1,0]	0	hSpCas9	positive selection	4233124
52698314	52698337	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.3964365801865314	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4233125
52692830	52692853	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	1.0351156327673618	[2]	[0,0,0,4]	7	hSpCas9	positive selection	4233127
52687825	52687848	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.21886044272171962	[4]	[4,1]	-4	hSpCas9	positive selection	4296940
52698218	52698241	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.2825086786862664	[2]	[3,2]	5	hSpCas9	positive selection	4296941
52692853	52692876	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	0.022722391288392374	[3]	[3,2]	0	hSpCas9	positive selection	4296942
52688072	52688095	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	0.008813861775541332	[3]	[2,2]	0	hSpCas9	positive selection	4361194
52698314	52698337	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	0.0638458667528472	[2]	[1,1]	1	hSpCas9	positive selection	4361195
52692830	52692853	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	0.021881462381147576	[3]	[2,2]	0	hSpCas9	positive selection	4361196
52687825	52687848	1	+	27260156	BXPC3	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.40620511120426017	[1437]	[893,1000,1170,1550]	-7	hSpCas9	negative selection	5569400
52698218	52698241	1	+	27260156	BXPC3	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.4063817336383355	[398]	[345,307,302,293]	-7	hSpCas9	negative selection	5569401
52692853	52692876	1	-	27260156	BXPC3	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.4007504899683112	[941]	[588,733,849,836]	-7	hSpCas9	negative selection	5569402
52688072	52688095	1	-	27260156	BXPC3	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.8465141156788585	[698]	[313,456,377,490]	-9	hSpCas9	negative selection	5633654
52698314	52698337	1	-	27260156	BXPC3	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	0.01869933200251961	[249]	[222,197,299,356]	0	hSpCas9	negative selection	5633655
52692830	52692853	1	-	27260156	BXPC3	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.5691432252663098	[704]	[463,380,524,642]	-8	hSpCas9	negative selection	5633656
52687825	52687848	1	+	27260156	A673	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.16509110316030573	[1437]	[1697,1498,1511,1462]	-4	hSpCas9	negative selection	5690651
52698218	52698241	1	+	27260156	A673	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.06496654619970546	[398]	[497,369,474,496]	-2	hSpCas9	negative selection	5690652
52692853	52692876	1	-	27260156	A673	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.25390360987237515	[941]	[980,922,940,951]	-6	hSpCas9	negative selection	5690653
52688072	52688095	1	-	27260156	A673	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.5108798310501176	[698]	[722,554,519,572]	-8	hSpCas9	negative selection	5754905
52698314	52698337	1	-	27260156	A673	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.1415601899750728	[249]	[334,221,304,231]	-4	hSpCas9	negative selection	5754906
52692830	52692853	1	-	27260156	A673	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.3646312430511888	[704]	[773,635,681,543]	-7	hSpCas9	negative selection	5754907
52687825	52687848	1	+	27260156	A375	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.4937233214275458	[1437]	[1322,1463,1007,1029]	-6	hSpCas9	negative selection	5811902
52698218	52698241	1	+	27260156	A375	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.9202552300601906	[398]	[263,373,228,146]	-8	hSpCas9	negative selection	5811903
52692853	52692876	1	-	27260156	A375	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-1.2020230609473372	[941]	[461,561,580,334]	-8	hSpCas9	negative selection	5811904
52688072	52688095	1	-	27260156	A375	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.7028920974835484	[698]	[273,297,177,257]	-9	hSpCas9	negative selection	5876156
52698314	52698337	1	-	27260156	A375	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	0.05958019914065693	[249]	[437,508,192,126]	0	hSpCas9	negative selection	5876157
52692830	52692853	1	-	27260156	A375	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.8473244748363435	[704]	[407,408,622,389]	-8	hSpCas9	negative selection	5876158
52687825	52687848	1	+	27260156	COLO741	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.2967678207582165	[1437]	[1522,1479,1483]	-6	hSpCas9	negative selection	5933153
52698218	52698241	1	+	27260156	COLO741	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.810303432437176	[398]	[267,315,285]	-9	hSpCas9	negative selection	5933154
52692853	52692876	1	-	27260156	COLO741	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.27867771674778596	[941]	[1080,745,1142]	-5	hSpCas9	negative selection	5933155
52688072	52688095	1	-	27260156	COLO741	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.41882262507222556	[698]	[756,708,552]	-7	hSpCas9	negative selection	5997407
52698314	52698337	1	-	27260156	COLO741	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.5180984321952827	[249]	[340,233,111]	-8	hSpCas9	negative selection	5997408
52692830	52692853	1	-	27260156	COLO741	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6333403633611356	[704]	[682,536,532]	-8	hSpCas9	negative selection	5997409
52687825	52687848	1	+	27260156	CAL120	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.19652397840791336	[1437]	[2031,1173,1548]	-3	hSpCas9	negative selection	6054404
52698218	52698241	1	+	27260156	CAL120	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.909208148275133	[398]	[325,194,280]	-8	hSpCas9	negative selection	6054405
52692853	52692876	1	-	27260156	CAL120	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.9079471711297602	[941]	[700,649,535]	-8	hSpCas9	negative selection	6054406
52688072	52688095	1	-	27260156	CAL120	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.8486690238383874	[698]	[671,418,387]	-8	hSpCas9	negative selection	6118658
52698314	52698337	1	-	27260156	CAL120	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-1.1914576767337741	[249]	[91,176,132]	-9	hSpCas9	negative selection	6118659
52692830	52692853	1	-	27260156	CAL120	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.7346845195239688	[704]	[454,557,556]	-8	hSpCas9	negative selection	6118660
52687825	52687848	1	+	27260156	CADOES1	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.22266228243905362	[1437]	[1177,1160,1138,1104]	-4	hSpCas9	negative selection	6175655
52698218	52698241	1	+	27260156	CADOES1	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.36863908652322175	[398]	[205,455,206,280]	-6	hSpCas9	negative selection	6175656
52692853	52692876	1	-	27260156	CADOES1	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.6021611221610087	[941]	[477,487,679,665]	-8	hSpCas9	negative selection	6175657
52688072	52688095	1	-	27260156	CADOES1	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.9539660204282617	[698]	[401,329,279,329]	-9	hSpCas9	negative selection	6239909
52698314	52698337	1	-	27260156	CADOES1	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.06546945769424262	[249]	[221,207,255,201]	-1	hSpCas9	negative selection	6239910
52692830	52692853	1	-	27260156	CADOES1	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.17102442731887002	[704]	[723,509,590,500]	-3	hSpCas9	negative selection	6239911
52687825	52687848	1	+	27260156	EWS502	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.08818384521433043	[1437]	[1171,1514,1535,1539]	-1	hSpCas9	negative selection	6296906
52698218	52698241	1	+	27260156	EWS502	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.48351626041865103	[398]	[255,295,272,394]	-7	hSpCas9	negative selection	6296907
52692853	52692876	1	-	27260156	EWS502	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.6454899384393047	[941]	[595,656,750,543]	-8	hSpCas9	negative selection	6296908
52688072	52688095	1	-	27260156	EWS502	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.120211791718435	[698]	[342,289,236,502]	-9	hSpCas9	negative selection	6361160
52698314	52698337	1	-	27260156	EWS502	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.39838492590678964	[249]	[167,210,190,238]	-6	hSpCas9	negative selection	6361161
52692830	52692853	1	-	27260156	EWS502	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.7894729200041435	[704]	[404,363,417,553]	-8	hSpCas9	negative selection	6361162
52687825	52687848	1	+	27260156	EW8	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.3652644707353636	[1437]	[1131,776,723,1037]	-6	hSpCas9	negative selection	6418157
52698218	52698241	1	+	27260156	EW8	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.8280481953925739	[398]	[160,266,123,183]	-9	hSpCas9	negative selection	6418158
52692853	52692876	1	-	27260156	EW8	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.7224576962136464	[941]	[415,415,478,529]	-8	hSpCas9	negative selection	6418159
52688072	52688095	1	-	27260156	EW8	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.8844772388693316	[698]	[442,259,261,283]	-9	hSpCas9	negative selection	6482411
52698314	52698337	1	-	27260156	EW8	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.4656141822301326	[249]	[141,228,107,113]	-7	hSpCas9	negative selection	6482412
52692830	52692853	1	-	27260156	EW8	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.5198340371899987	[704]	[526,480,313,299]	-7	hSpCas9	negative selection	6482413
52687825	52687848	1	+	27260156	CORL105	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.39514578136919654	[1437]	[1232,1454,1195,1217]	-6	hSpCas9	negative selection	6539408
52698218	52698241	1	+	27260156	CORL105	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.26282864847764453	[398]	[365,320,393,476]	-5	hSpCas9	negative selection	6539409
52692853	52692876	1	-	27260156	CORL105	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.6718284434908357	[941]	[819,690,675,583]	-8	hSpCas9	negative selection	6539410
52688072	52688095	1	-	27260156	CORL105	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.7901687794573892	[698]	[463,451,612,385]	-8	hSpCas9	negative selection	6603662
52698314	52698337	1	-	27260156	CORL105	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.35707360486349893	[249]	[260,187,235,231]	-6	hSpCas9	negative selection	6603663
52692830	52692853	1	-	27260156	CORL105	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.631516282533977	[704]	[585,592,501,445]	-8	hSpCas9	negative selection	6603664
52687825	52687848	1	+	27260156	HS294T	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.1841500176723072	[1437]	[316,453,582,645]	-3	hSpCas9	negative selection	6660659
52698218	52698241	1	+	27260156	HS294T	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.7441115792993556	[398]	[59,64,100,156]	-8	hSpCas9	negative selection	6660660
52692853	52692876	1	-	27260156	HS294T	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.9075201083100825	[941]	[167,151,200,271]	-8	hSpCas9	negative selection	6660661
52688072	52688095	1	-	27260156	HS294T	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.1403332210375803	[698]	[111,72,143,171]	-9	hSpCas9	negative selection	6724913
52698314	52698337	1	-	27260156	HS294T	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.551894748030188	[249]	[58,71,56,77]	-7	hSpCas9	negative selection	6724914
52692830	52692853	1	-	27260156	HS294T	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-1.2063134726310762	[704]	[91,88,139,161]	-9	hSpCas9	negative selection	6724915
52687825	52687848	1	+	27260156	HCC44	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.446666243043115	[1437]	[1325,1006,1205,1262]	-6	hSpCas9	negative selection	6781910
52698218	52698241	1	+	27260156	HCC44	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-1.230086240823748	[398]	[184,271,128,159]	-9	hSpCas9	negative selection	6781911
52692853	52692876	1	-	27260156	HCC44	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-1.560665863239946	[941]	[324,390,364,353]	-9	hSpCas9	negative selection	6781912
52688072	52688095	1	-	27260156	HCC44	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-2.3883105554830024	[698]	[130,167,127,166]	-9	hSpCas9	negative selection	6846164
52698314	52698337	1	-	27260156	HCC44	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-1.0529489653523076	[249]	[210,92,97,147]	-8	hSpCas9	negative selection	6846165
52692830	52692853	1	-	27260156	HCC44	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.9948942073768638	[704]	[350,305,629,359]	-8	hSpCas9	negative selection	6846166
52687825	52687848	1	+	27260156	G402	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.29109680413866146	[1437]	[1318,1471,1338,1578]	-4	hSpCas9	negative selection	6903161
52698218	52698241	1	+	27260156	G402	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.9610263255189889	[398]	[267,150,88,476]	-8	hSpCas9	negative selection	6903162
52692853	52692876	1	-	27260156	G402	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.8663414941715976	[941]	[791,481,581,675]	-7	hSpCas9	negative selection	6903163
52688072	52688095	1	-	27260156	G402	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.7797429074833588	[698]	[336,172,283,208]	-9	hSpCas9	negative selection	6967415
52698314	52698337	1	-	27260156	G402	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	0.007459804815871052	[249]	[345,310,388,190]	0	hSpCas9	negative selection	6967416
52692830	52692853	1	-	27260156	G402	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.9450853688193117	[704]	[622,667,386,159]	-8	hSpCas9	negative selection	6967417
52687825	52687848	1	+	27260156	L33	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.07280678649892036	[1437]	[1212,539,990,1365]	-2	hSpCas9	negative selection	7024412
52698218	52698241	1	+	27260156	L33	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.2376673684260305	[398]	[333,125,233,339]	-5	hSpCas9	negative selection	7024413
52692853	52692876	1	-	27260156	L33	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.8747522709807177	[941]	[447,211,330,563]	-9	hSpCas9	negative selection	7024414
52688072	52688095	1	-	27260156	L33	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.21967538274321619	[698]	[678,205,359,643]	-5	hSpCas9	negative selection	7088666
52698314	52698337	1	-	27260156	L33	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.7436753071742167	[249]	[123,56,105,165]	-9	hSpCas9	negative selection	7088667
52692830	52692853	1	-	27260156	L33	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.7533238074592484	[704]	[467,189,268,312]	-9	hSpCas9	negative selection	7088668
52687825	52687848	1	+	27260156	K562	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	0.02251643671489112	[1437]	[1502,1571,1238,938]	0	hSpCas9	negative selection	7145663
52698218	52698241	1	+	27260156	K562	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.5365310496938643	[398]	[138,131,106,546]	-6	hSpCas9	negative selection	7145664
52692853	52692876	1	-	27260156	K562	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.35608537953558606	[941]	[635,612,975,409]	-4	hSpCas9	negative selection	7145665
52688072	52688095	1	-	27260156	K562	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.5421797528315229	[698]	[122,175,133,387]	-9	hSpCas9	negative selection	7209917
52698314	52698337	1	-	27260156	K562	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.3699792566177219	[249]	[95,313,225,63]	-4	hSpCas9	negative selection	7209918
52692830	52692853	1	-	27260156	K562	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-1.282745205225929	[704]	[192,421,206,213]	-8	hSpCas9	negative selection	7209919
52687825	52687848	1	+	27260156	HT29	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.19823671176220592	[1437]	[1675,1729,1525,1218]	-4	hSpCas9	negative selection	7266914
52698218	52698241	1	+	27260156	HT29	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.3815080315791691	[398]	[425,342,398,325]	-6	hSpCas9	negative selection	7266915
52692853	52692876	1	-	27260156	HT29	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.1822198125359209	[941]	[1132,913,1136,864]	-4	hSpCas9	negative selection	7266916
52688072	52688095	1	-	27260156	HT29	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.49267186135961927	[698]	[604,697,643,486]	-7	hSpCas9	negative selection	7331168
52698314	52698337	1	-	27260156	HT29	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.06511079489211802	[249]	[245,307,331,273]	-1	hSpCas9	negative selection	7331169
52692830	52692853	1	-	27260156	HT29	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.2426444371688672	[704]	[837,594,770,689]	-5	hSpCas9	negative selection	7331170
52687825	52687848	1	+	27260156	MHHES1	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.3393618080796401	[1437]	[1412,1402,1368,1000]	-6	hSpCas9	negative selection	7388165
52698218	52698241	1	+	27260156	MHHES1	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.5299812048029718	[398]	[317,595,239,150]	-7	hSpCas9	negative selection	7388166
52692853	52692876	1	-	27260156	MHHES1	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.42761890376118306	[941]	[783,1051,661,687]	-7	hSpCas9	negative selection	7388167
52688072	52688095	1	-	27260156	MHHES1	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.929574872926167	[698]	[425,430,382,407]	-9	hSpCas9	negative selection	7452419
52698314	52698337	1	-	27260156	MHHES1	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.6675176550086016	[249]	[196,109,242,155]	-8	hSpCas9	negative selection	7452420
52692830	52692853	1	-	27260156	MHHES1	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.4856539108125264	[704]	[731,690,544,366]	-7	hSpCas9	negative selection	7452421
52687825	52687848	1	+	27260156	MEWO	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.2874165095664396	[1437]	[1295,949,1098]	-6	hSpCas9	negative selection	7509416
52698218	52698241	1	+	27260156	MEWO	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.15411512010140632	[398]	[450,400,400]	3	hSpCas9	negative selection	7509417
52692853	52692876	1	-	27260156	MEWO	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	0.01944154375068896	[941]	[905,900,874]	0	hSpCas9	negative selection	7509418
52688072	52688095	1	-	27260156	MEWO	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.34327413749876917	[698]	[706,399,476]	-6	hSpCas9	negative selection	7573670
52698314	52698337	1	-	27260156	MEWO	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.25216995753666527	[249]	[164,200,216]	-5	hSpCas9	negative selection	7573671
52692830	52692853	1	-	27260156	MEWO	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.3879053875553744	[704]	[542,429,546]	-7	hSpCas9	negative selection	7573672
52687825	52687848	1	+	27260156	LNCAPCLONEFGC	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	0.10605043631174293	[1437]	[1300,1170,1932,1297]	1	hSpCas9	negative selection	7630667
52698218	52698241	1	+	27260156	LNCAPCLONEFGC	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.7771082015190928	[398]	[177,225,182,251]	-8	hSpCas9	negative selection	7630668
52692853	52692876	1	-	27260156	LNCAPCLONEFGC	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.777821095083558	[941]	[517,422,544,515]	-8	hSpCas9	negative selection	7630669
52688072	52688095	1	-	27260156	LNCAPCLONEFGC	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.9774390316082802	[698]	[427,194,284,378]	-8	hSpCas9	negative selection	7694921
52698314	52698337	1	-	27260156	LNCAPCLONEFGC	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.6862164593529646	[249]	[160,88,228,99]	-8	hSpCas9	negative selection	7694922
52692830	52692853	1	-	27260156	LNCAPCLONEFGC	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6239485220704144	[704]	[431,438,438,348]	-7	hSpCas9	negative selection	7694923
52687825	52687848	1	+	27260156	PANC0327	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.15654363772498603	[1437]	[1318,923,1322,1060]	-2	hSpCas9	negative selection	7751918
52698218	52698241	1	+	27260156	PANC0327	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.6664209656665708	[398]	[207,261,233,182]	-7	hSpCas9	negative selection	7751919
52692853	52692876	1	-	27260156	PANC0327	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.7568633130225388	[941]	[383,608,563,399]	-8	hSpCas9	negative selection	7751920
52688072	52688095	1	-	27260156	PANC0327	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.6638763680249415	[698]	[370,381,351,461]	-7	hSpCas9	negative selection	7816172
52698314	52698337	1	-	27260156	PANC0327	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.4324265014146237	[249]	[220,161,83,195]	-6	hSpCas9	negative selection	7816173
52692830	52692853	1	-	27260156	PANC0327	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.7635702272785418	[704]	[418,179,442,461]	-8	hSpCas9	negative selection	7816174
52687825	52687848	1	+	27260156	NCIH2009	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.529849247597056	[1437]	[1568,1523,1111]	-6	hSpCas9	negative selection	7873169
52698218	52698241	1	+	27260156	NCIH2009	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.3779146700381528	[398]	[518,486,296]	-5	hSpCas9	negative selection	7873170
52692853	52692876	1	-	27260156	NCIH2009	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.8658047807104643	[941]	[922,671,610]	-8	hSpCas9	negative selection	7873171
52688072	52688095	1	-	27260156	NCIH2009	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.6142408723854174	[698]	[417,264,293]	-9	hSpCas9	negative selection	7937423
52698314	52698337	1	-	27260156	NCIH2009	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.43836404279728114	[249]	[191,249,317]	-5	hSpCas9	negative selection	7937424
52692830	52692853	1	-	27260156	NCIH2009	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-1.0574569229418775	[704]	[553,415,465]	-8	hSpCas9	negative selection	7937425
52687825	52687848	1	+	27260156	NCIH1373	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.42428342471188163	[1437]	[1176,974,1367,341]	-4	hSpCas9	negative selection	7994420
52698218	52698241	1	+	27260156	NCIH1373	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.5908090135374153	[398]	[423,214,380,48]	-5	hSpCas9	negative selection	7994421
52692853	52692876	1	-	27260156	NCIH1373	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.7898801988341679	[941]	[377,541,917,147]	-7	hSpCas9	negative selection	7994422
52688072	52688095	1	-	27260156	NCIH1373	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.7552936294120673	[698]	[225,253,204,62]	-9	hSpCas9	negative selection	8058674
52698314	52698337	1	-	27260156	NCIH1373	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-1.026182881233868	[249]	[106,215,143,16]	-8	hSpCas9	negative selection	8058675
52692830	52692853	1	-	27260156	NCIH1373	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-1.006324102388269	[704]	[413,345,398,110]	-7	hSpCas9	negative selection	8058676
52687825	52687848	1	+	27260156	PATU8902	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.12706170570649822	[1437]	[2230,1958,1483,1718]	-1	hSpCas9	negative selection	8115671
52698218	52698241	1	+	27260156	PATU8902	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.5857052944096659	[398]	[285,425,367,403]	-5	hSpCas9	negative selection	8115672
52692853	52692876	1	-	27260156	PATU8902	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.1601620094861237	[941]	[1052,1293,999,1415]	-2	hSpCas9	negative selection	8115673
52688072	52688095	1	-	27260156	PATU8902	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.0360321617070263	[698]	[723,412,277,534]	-7	hSpCas9	negative selection	8179925
52698314	52698337	1	-	27260156	PATU8902	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.47225838263155884	[249]	[233,476,181,110]	-4	hSpCas9	negative selection	8179926
52692830	52692853	1	-	27260156	PATU8902	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.5280367262597113	[704]	[680,848,293,1037]	-5	hSpCas9	negative selection	8179927
52687825	52687848	1	+	27260156	PANC1	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.28551115668685645	[1437]	[997,1251,912,934]	-4	hSpCas9	negative selection	8236922
52698218	52698241	1	+	27260156	PANC1	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-1.3763282376787163	[398]	[150,142,78,150]	-9	hSpCas9	negative selection	8236923
52692853	52692876	1	-	27260156	PANC1	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.8295775497147925	[941]	[457,466,490,407]	-8	hSpCas9	negative selection	8236924
52688072	52688095	1	-	27260156	PANC1	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.458181033368933	[698]	[123,133,363,231]	-9	hSpCas9	negative selection	8301176
52698314	52698337	1	-	27260156	PANC1	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.43990849182655134	[249]	[214,176,98,143]	-6	hSpCas9	negative selection	8301177
52692830	52692853	1	-	27260156	PANC1	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6548144675959998	[704]	[349,549,440,248]	-7	hSpCas9	negative selection	8301178
52687825	52687848	1	+	27260156	PANC0813	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.35317001899782885	[1437]	[1408,1542,1076,1267]	-5	hSpCas9	negative selection	8358173
52698218	52698241	1	+	27260156	PANC0813	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.056500631752535224	[398]	[591,447,409,506]	0	hSpCas9	negative selection	8358174
52692853	52692876	1	-	27260156	PANC0813	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.24954148413036603	[941]	[841,928,948,989]	-4	hSpCas9	negative selection	8358175
52688072	52688095	1	-	27260156	PANC0813	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.5109721120277247	[698]	[668,560,710,382]	-6	hSpCas9	negative selection	8422427
52698314	52698337	1	-	27260156	PANC0813	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.22195142155632175	[249]	[351,227,137,294]	-4	hSpCas9	negative selection	8422428
52692830	52692853	1	-	27260156	PANC0813	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.49089377429963355	[704]	[581,796,362,610]	-6	hSpCas9	negative selection	8422429
52687825	52687848	1	+	27260156	RDES	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.1782805161688743	[1437]	[1316,1402,1637,1487]	-3	hSpCas9	negative selection	8479424
52698218	52698241	1	+	27260156	RDES	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.30924816215694617	[398]	[314,376,454,330]	-5	hSpCas9	negative selection	8479425
52692853	52692876	1	-	27260156	RDES	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.3131968522755282	[941]	[773,831,915,980]	-5	hSpCas9	negative selection	8479426
52688072	52688095	1	-	27260156	RDES	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.7564853319324714	[698]	[382,387,660,495]	-8	hSpCas9	negative selection	8543678
52698314	52698337	1	-	27260156	RDES	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.360222571964362	[249]	[140,207,281,290]	-6	hSpCas9	negative selection	8543679
52692830	52692853	1	-	27260156	RDES	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.5534212440671664	[704]	[418,640,536,626]	-7	hSpCas9	negative selection	8543680
52687825	52687848	1	+	27260156	PC3	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.02352973053523355	[1437]	[901,1250,2431,1552]	0	hSpCas9	negative selection	8600675
52698218	52698241	1	+	27260156	PC3	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.49647999305197654	[398]	[171,372,407,236]	-8	hSpCas9	negative selection	8600676
52692853	52692876	1	-	27260156	PC3	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.233012451103788	[941]	[494,719,1400,878]	-5	hSpCas9	negative selection	8600677
52688072	52688095	1	-	27260156	PC3	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.7266477630901593	[698]	[254,349,770,484]	-9	hSpCas9	negative selection	8664929
52698314	52698337	1	-	27260156	PC3	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.570401681919514	[249]	[140,167,194,167]	-8	hSpCas9	negative selection	8664930
52692830	52692853	1	-	27260156	PC3	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.3648284375466197	[704]	[261,682,802,610]	-7	hSpCas9	negative selection	8664931
52687825	52687848	1	+	27260156	PATU8988T	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.36552378604731994	[1437]	[937,1143,1040,1207]	-6	hSpCas9	negative selection	8721926
52698218	52698241	1	+	27260156	PATU8988T	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-1.090606757563586	[398]	[146,163,247,160]	-9	hSpCas9	negative selection	8721927
52692853	52692876	1	-	27260156	PATU8988T	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.7817585840511504	[941]	[401,467,606,642]	-8	hSpCas9	negative selection	8721928
52688072	52688095	1	-	27260156	PATU8988T	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-1.138460222744404	[698]	[204,225,471,314]	-9	hSpCas9	negative selection	8786180
52698314	52698337	1	-	27260156	PATU8988T	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.14878544736668575	[249]	[141,343,178,218]	-3	hSpCas9	negative selection	8786181
52692830	52692853	1	-	27260156	PATU8988T	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-1.3305096365036362	[704]	[244,313,244,284]	-9	hSpCas9	negative selection	8786182
52687825	52687848	1	+	27260156	T47D	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.16962605574299539	[1437]	[1484,1554,1391,1521]	-4	hSpCas9	negative selection	8843177
52698218	52698241	1	+	27260156	T47D	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.49832156853847753	[398]	[418,286,323,288]	-8	hSpCas9	negative selection	8843178
52692853	52692876	1	-	27260156	T47D	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.5686192715494449	[941]	[742,712,815,686]	-8	hSpCas9	negative selection	8843179
52688072	52688095	1	-	27260156	T47D	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.7798673989284669	[698]	[428,466,537,461]	-9	hSpCas9	negative selection	8907431
52698314	52698337	1	-	27260156	T47D	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.061946393920656484	[249]	[296,282,256,278]	-1	hSpCas9	negative selection	8907432
52692830	52692853	1	-	27260156	T47D	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.4125797949545246	[704]	[565,599,707,592]	-7	hSpCas9	negative selection	8907433
52687825	52687848	1	+	27260156	SU8686	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.1982110906273935	[1437]	[1156,1118,1261,1489]	-3	hSpCas9	negative selection	8964428
52698218	52698241	1	+	27260156	SU8686	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.10593649886279563	[398]	[299,411,328,438]	-2	hSpCas9	negative selection	8964429
52692853	52692876	1	-	27260156	SU8686	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.2642035364847892	[941]	[590,647,862,1094]	-4	hSpCas9	negative selection	8964430
52688072	52688095	1	-	27260156	SU8686	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.5784575279508781	[698]	[466,398,513,485]	-7	hSpCas9	negative selection	9028682
52698314	52698337	1	-	27260156	SU8686	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.3530156241963808	[249]	[166,131,219,281]	-5	hSpCas9	negative selection	9028683
52692830	52692853	1	-	27260156	SU8686	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6854671752628357	[704]	[518,286,336,630]	-7	hSpCas9	negative selection	9028684
52687825	52687848	1	+	27260156	SKES1	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.22049266552378777	[1437]	[1321,1493,1120,1042]	-5	hSpCas9	negative selection	9085679
52698218	52698241	1	+	27260156	SKES1	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	0.04896235349518785	[398]	[529,527,280,343]	1	hSpCas9	negative selection	9085680
52692853	52692876	1	-	27260156	SKES1	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.38143403723924574	[941]	[850,716,609,718]	-7	hSpCas9	negative selection	9085681
52688072	52688095	1	-	27260156	SKES1	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.46794201509738137	[698]	[607,488,404,520]	-8	hSpCas9	negative selection	9149933
52698314	52698337	1	-	27260156	SKES1	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.3690511293974893	[249]	[251,149,141,225]	-7	hSpCas9	negative selection	9149934
52692830	52692853	1	-	27260156	SKES1	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6211545514721054	[704]	[481,507,433,414]	-8	hSpCas9	negative selection	9149935
52687825	52687848	1	+	27260156	TOV112D	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.12913393342090895	[1437]	[1123,2216,966,1166]	-3	hSpCas9	negative selection	9206930
52698218	52698241	1	+	27260156	TOV112D	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.7538444198976437	[398]	[144,269,153,374]	-9	hSpCas9	negative selection	9206931
52692853	52692876	1	-	27260156	TOV112D	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.5192417819645931	[941]	[539,431,594,989]	-8	hSpCas9	negative selection	9206932
52688072	52688095	1	-	27260156	TOV112D	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.8960054164223028	[698]	[292,474,358,393]	-9	hSpCas9	negative selection	9271184
52698314	52698337	1	-	27260156	TOV112D	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.34972289855476457	[249]	[232,224,78,256]	-6	hSpCas9	negative selection	9271185
52692830	52692853	1	-	27260156	TOV112D	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.3652537106729348	[704]	[640,603,517,452]	-6	hSpCas9	negative selection	9271186
52687825	52687848	1	+	27260156	TC71	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.33675629623058834	[1437]	[1104,1286,1240,1252]	-7	hSpCas9	negative selection	9328181
52698218	52698241	1	+	27260156	TC71	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.09991795923903449	[398]	[351,441,405,396]	-3	hSpCas9	negative selection	9328182
52692853	52692876	1	-	27260156	TC71	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.44481381708787426	[941]	[705,763,722,777]	-8	hSpCas9	negative selection	9328183
52688072	52688095	1	-	27260156	TC71	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.5255333472966838	[698]	[519,568,509,480]	-9	hSpCas9	negative selection	9392435
52698314	52698337	1	-	27260156	TC71	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.14362240575333407	[249]	[241,224,257,244]	-4	hSpCas9	negative selection	9392436
52692830	52692853	1	-	27260156	TC71	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.4609169684608334	[704]	[654,472,475,594]	-8	hSpCas9	negative selection	9392437
52687825	52687848	1	+	27260156	TC32	viability	CCCCAGCTTGTACATGCGACTGG	COA7	ENSG00000162377	-0.07410248332551328	[1437]	[1051,1030,1554,1610]	-1	hSpCas9	negative selection	9449432
52698218	52698241	1	+	27260156	TC32	viability	CACCGTCCGGGTCCTTCTCGTGG	COA7	ENSG00000162377	-0.19738340694196074	[398]	[234,232,527,378]	-4	hSpCas9	negative selection	9449433
52692853	52692876	1	-	27260156	TC32	viability	TCTCGCAGGTTGCTATCGGCTGG	COA7	ENSG00000162377	-0.3661436209444452	[941]	[619,500,798,896]	-6	hSpCas9	negative selection	9449434
52688072	52688095	1	-	27260156	TC32	viability	ATAGCAGCATGTCACAACGTTGG	COA7	ENSG00000162377	-0.5874500094677877	[698]	[543,272,602,375]	-8	hSpCas9	negative selection	9513686
52698314	52698337	1	-	27260156	TC32	viability	GGCGCGAACCATGGCCGGCATGG	COA7	ENSG00000162377	-0.2603213663005183	[249]	[129,142,288,259]	-5	hSpCas9	negative selection	9513687
52692830	52692853	1	-	27260156	TC32	viability	TGGACTATTTGGAAGGGATCCGG	COA7	ENSG00000162377	-0.6222822831503512	[704]	[461,380,514,360]	-8	hSpCas9	negative selection	9513688