Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1291
• Symbol: COL6A1
• Description: collagen type VI alpha 1 chain

DataSource: http://genomecrispr.dkfz.de/#!/results/COL6A1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45986979	45987002	21	+	26472758	Jiyoye	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	2.3331748000620967	[9]	[37]	9	hSpCas9	negative selection	35258
45989082	45989105	21	+	26472758	Jiyoye	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.5793563568885537	[70]	[79]	4	hSpCas9	negative selection	35259
45990389	45990412	21	+	26472758	Jiyoye	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-1.1136567817955672	[65]	[22]	-6	hSpCas9	negative selection	35260
45981838	45981861	21	+	26472758	Jiyoye	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	0.3778314199237291	[148]	[145]	3	hSpCas9	negative selection	35261
45981909	45981932	21	+	26472758	Jiyoye	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.9307373375628865	[79]	[114]	6	hSpCas9	negative selection	35262
45982623	45982646	21	+	26472758	Jiyoye	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	-0.14942856406156735	[402]	[273]	-1	hSpCas9	negative selection	35263
45984311	45984334	21	+	26472758	Jiyoye	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-3.48764238180207	[118]	[7]	-9	hSpCas9	negative selection	35264
45986584	45986607	21	+	26472758	Jiyoye	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.6312987663087625	[75]	[36]	-4	hSpCas9	negative selection	35265
45986643	45986666	21	+	26472758	Jiyoye	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	0.07182677085618952	[134]	[106]	0	hSpCas9	negative selection	35266
45986949	45986972	21	+	26472758	Jiyoye	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.47756470939727125	[19]	[20]	3	hSpCas9	negative selection	35267
45986979	45987002	21	+	26472758	KBM7	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.002880207131565893	[97,107]	[42,53]	0	hSpCas9	negative selection	226376
45989082	45989105	21	+	26472758	KBM7	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.4114008115256056	[435,457]	[345,223]	4	hSpCas9	negative selection	226377
45990389	45990412	21	+	26472758	KBM7	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.3990086441480657	[257,135]	[111,124]	4	hSpCas9	negative selection	226378
45981838	45981861	21	+	26472758	KBM7	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	0.053696328865450144	[678,416]	[182,332]	0	hSpCas9	negative selection	226379
45981909	45981932	21	+	26472758	KBM7	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.5077650676214567	[228,144]	[117,126]	5	hSpCas9	negative selection	226380
45982623	45982646	21	+	26472758	KBM7	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.719893686174455	[1001,735]	[689,643]	7	hSpCas9	negative selection	226381
45984311	45984334	21	+	26472758	KBM7	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.9820285699332154	[116,179]	[73,201]	9	hSpCas9	negative selection	226382
45986584	45986607	21	+	26472758	KBM7	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.8559169387981416	[169,130]	[61,17]	-6	hSpCas9	negative selection	226383
45986643	45986666	21	+	26472758	KBM7	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	0.17178724262181216	[384,313]	[172,193]	1	hSpCas9	negative selection	226384
45986949	45986972	21	+	26472758	KBM7	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	1.254119614291703	[156,138]	[226,110]	9	hSpCas9	negative selection	226385
45986979	45987002	21	+	26472758	Raji	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.744813455988891	[35]	[13]	7	hSpCas9	negative selection	417494
45989082	45989105	21	+	26472758	Raji	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	1.3207871734827927	[137]	[79]	9	hSpCas9	negative selection	417495
45990389	45990412	21	+	26472758	Raji	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.8795776178507873	[88]	[37]	7	hSpCas9	negative selection	417496
45981838	45981861	21	+	26472758	Raji	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-1.2849338874051608	[272]	[25]	-7	hSpCas9	negative selection	417497
45981909	45981932	21	+	26472758	Raji	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	1.4717949615824752	[86]	[55]	9	hSpCas9	negative selection	417498
45982623	45982646	21	+	26472758	Raji	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	1.116136009382563	[492]	[247]	8	hSpCas9	negative selection	417499
45984311	45984334	21	+	26472758	Raji	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.8634579524875103	[44]	[18]	7	hSpCas9	negative selection	417500
45986584	45986607	21	+	26472758	Raji	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.1821230818213855	[87]	[8]	-7	hSpCas9	negative selection	417501
45986643	45986666	21	+	26472758	Raji	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	0.8721670736795678	[225]	[95]	7	hSpCas9	negative selection	417502
45986949	45986972	21	+	26472758	Raji	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.2448870591235346	[79]	[21]	2	hSpCas9	negative selection	417503
45986979	45987002	21	+	26472758	K562	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	1.1837559457598226	[84]	[162]	8	hSpCas9	negative selection	608612
45989082	45989105	21	+	26472758	K562	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	-0.9391812106729421	[317]	[139]	-5	hSpCas9	negative selection	608613
45990389	45990412	21	+	26472758	K562	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.19437804516685153	[175]	[169]	1	hSpCas9	negative selection	608614
45981838	45981861	21	+	26472758	K562	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.31935844316408146	[506]	[342]	-2	hSpCas9	negative selection	608615
45981909	45981932	21	+	26472758	K562	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.08856455572991107	[130]	[103]	0	hSpCas9	negative selection	608616
45982623	45982646	21	+	26472758	K562	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.019838747092234987	[769]	[658]	0	hSpCas9	negative selection	608617
45984311	45984334	21	+	26472758	K562	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.22272365656712778	[133]	[131]	1	hSpCas9	negative selection	608618
45986584	45986607	21	+	26472758	K562	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.1667767053180027	[124]	[46]	-6	hSpCas9	negative selection	608619
45986643	45986666	21	+	26472758	K562	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.2473115286068815	[366]	[260]	-2	hSpCas9	negative selection	608620
45986949	45986972	21	+	26472758	K562	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-0.683431486577718	[155]	[81]	-4	hSpCas9	negative selection	608621
45981891	45981914	21	-	26627737	DLD1	viability	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.2695007808355747	[342]	[30,270,96]	2	hSpCas9	negative selection	816555
45982742	45982765	21	+	26627737	DLD1	viability	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.27228352195240213	[526]	[215,203,179]	3	hSpCas9	negative selection	816556
45984395	45984418	21	+	26627737	DLD1	viability	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.5160153467230697	[593]	[218,402,191]	5	hSpCas9	negative selection	816557
45986552	45986575	21	+	26627737	DLD1	viability	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.6680400889942597	[487]	[214,256,253]	6	hSpCas9	negative selection	816558
45987642	45987665	21	-	26627737	DLD1	viability	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.06620697880117099	[1814]	[699,540,545]	0	hSpCas9	negative selection	816559
45990246	45990269	21	+	26627737	DLD1	viability	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	1.0501368126074309	[34]	[23,15,26]	8	hSpCas9	negative selection	816560
45981891	45981914	21	-	26627737	GBM cells	viability after 5 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.4180238283122162	[126]	[102,78]	6	hSpCas9	negative selection	898870
45982742	45982765	21	+	26627737	GBM cells	viability after 5 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.0961027176000587	[288]	[92,196]	-1	hSpCas9	negative selection	898871
45984395	45984418	21	+	26627737	GBM cells	viability after 5 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.3884961062174446	[381]	[137,174]	-6	hSpCas9	negative selection	898872
45986552	45986575	21	+	26627737	GBM cells	viability after 5 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.032645069012438285	[246]	[144,113]	0	hSpCas9	negative selection	898873
45987642	45987665	21	-	26627737	GBM cells	viability after 5 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.12950519980747655	[768]	[423,329]	-2	hSpCas9	negative selection	898874
45990246	45990269	21	+	26627737	GBM cells	viability after 5 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-1.5161236243931584	[15]	[0,4]	-9	hSpCas9	negative selection	898875
45981891	45981914	21	-	26627737	GBM cells	viability after 13 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.48895017923762524	[126]	[131,67]	6	hSpCas9	negative selection	981185
45982742	45982765	21	+	26627737	GBM cells	viability after 13 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.21840686317500962	[288]	[225,146]	3	hSpCas9	negative selection	981186
45984395	45984418	21	+	26627737	GBM cells	viability after 13 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.442382054854346	[381]	[178,130]	-5	hSpCas9	negative selection	981187
45986552	45986575	21	+	26627737	GBM cells	viability after 13 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.5607869019062606	[246]	[184,207]	7	hSpCas9	negative selection	981188
45987642	45987665	21	-	26627737	GBM cells	viability after 13 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.17674228516309376	[768]	[356,378]	-2	hSpCas9	negative selection	981189
45990246	45990269	21	+	26627737	GBM cells	viability after 13 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.8368532561642001	[15]	[0,7]	-7	hSpCas9	negative selection	981190
45981891	45981914	21	-	26627737	GBM cells	viability after 21 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.05074720769274643	[126]	[83,59]	0	hSpCas9	negative selection	1063500
45982742	45982765	21	+	26627737	GBM cells	viability after 21 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-1.1294503743263051	[288]	[88,55]	-7	hSpCas9	negative selection	1063501
45984395	45984418	21	+	26627737	GBM cells	viability after 21 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.42957650354693144	[381]	[151,155]	-4	hSpCas9	negative selection	1063502
45986552	45986575	21	+	26627737	GBM cells	viability after 21 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.49631198625164374	[246]	[205,173]	5	hSpCas9	negative selection	1063503
45987642	45987665	21	-	26627737	GBM cells	viability after 21 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.12502927280965026	[768]	[368,395]	-1	hSpCas9	negative selection	1063504
45990246	45990269	21	+	26627737	GBM cells	viability after 21 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-3.1197667003843415	[15]	[0,0]	-9	hSpCas9	negative selection	1063505
45981891	45981914	21	-	26627737	RPE1	viability after 9 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	3.2465706676042347	[29]	[34,158]	9	hSpCas9	negative selection	1145815
45982742	45982765	21	+	26627737	RPE1	viability after 9 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.660913905162749	[533]	[300,216]	4	hSpCas9	negative selection	1145816
45984395	45984418	21	+	26627737	RPE1	viability after 9 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.7109370917298632	[642]	[363,284]	5	hSpCas9	negative selection	1145817
45986552	45986575	21	+	26627737	RPE1	viability after 9 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.32195433488538605	[1155]	[268,315]	-2	hSpCas9	negative selection	1145818
45987642	45987665	21	-	26627737	RPE1	viability after 9 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.24332133869990935	[3095]	[579,1126]	-2	hSpCas9	negative selection	1145819
45990246	45990269	21	+	26627737	RPE1	viability after 9 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	0.03317481183197035	[148]	[7,98]	0	hSpCas9	negative selection	1145820
45981891	45981914	21	-	26627737	RPE1	viability after 12 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	3.0959519910197377	[29]	[65,71]	9	hSpCas9	negative selection	1228130
45982742	45982765	21	+	26627737	RPE1	viability after 12 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.7159610804087259	[533]	[274,193]	4	hSpCas9	negative selection	1228131
45984395	45984418	21	+	26627737	RPE1	viability after 12 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.9511407768192426	[642]	[282,387]	6	hSpCas9	negative selection	1228132
45986552	45986575	21	+	26627737	RPE1	viability after 12 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.6480011185284151	[1155]	[255,136]	-4	hSpCas9	negative selection	1228133
45987642	45987665	21	-	26627737	RPE1	viability after 12 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.1822402628240194	[3095]	[548,927]	-1	hSpCas9	negative selection	1228134
45990246	45990269	21	+	26627737	RPE1	viability after 12 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-1.3282188139048028	[148]	[13,17]	-7	hSpCas9	negative selection	1228135
45981891	45981914	21	-	26627737	RPE1	viability after 15 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	4.1303857876437835	[29]	[225,73]	9	hSpCas9	negative selection	1310445
45982742	45982765	21	+	26627737	RPE1	viability after 15 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.7648601827554635	[533]	[302,211]	5	hSpCas9	negative selection	1310446
45984395	45984418	21	+	26627737	RPE1	viability after 15 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.5157681242476739	[642]	[312,208]	3	hSpCas9	negative selection	1310447
45986552	45986575	21	+	26627737	RPE1	viability after 15 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.6753694915683544	[1155]	[189,218]	-4	hSpCas9	negative selection	1310448
45987642	45987665	21	-	26627737	RPE1	viability after 15 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.33815330059587123	[3095]	[872,518]	-2	hSpCas9	negative selection	1310449
45990246	45990269	21	+	26627737	RPE1	viability after 15 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.2429909814711233	[148]	[0,68]	-1	hSpCas9	negative selection	1310450
45981891	45981914	21	-	26627737	RPE1	viability after 18 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	2.7662492151094487	[29]	[71,36]	9	hSpCas9	negative selection	1392760
45982742	45982765	21	+	26627737	RPE1	viability after 18 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.8909225216348782	[533]	[375,150]	5	hSpCas9	negative selection	1392761
45984395	45984418	21	+	26627737	RPE1	viability after 18 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.4444763286793926	[642]	[108,371]	3	hSpCas9	negative selection	1392762
45986552	45986575	21	+	26627737	RPE1	viability after 18 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.29837743461945526	[1155]	[258,247]	-2	hSpCas9	negative selection	1392763
45987642	45987665	21	-	26627737	RPE1	viability after 18 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.4824626539376422	[3095]	[452,752]	-3	hSpCas9	negative selection	1392764
45990246	45990269	21	+	26627737	RPE1	viability after 18 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.11543439946490963	[148]	[25,48]	0	hSpCas9	negative selection	1392765
45981891	45981914	21	-	26627737	HeLa	viability after 8 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.6195567902033057	[98]	[117,55,37]	5	hSpCas9	negative selection	1475075
45982742	45982765	21	+	26627737	HeLa	viability after 8 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-1.5655828597116668	[640]	[49,158,65]	-9	hSpCas9	negative selection	1475076
45984395	45984418	21	+	26627737	HeLa	viability after 8 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.6616798320103499	[1057]	[320,168,382]	-6	hSpCas9	negative selection	1475077
45986552	45986575	21	+	26627737	HeLa	viability after 8 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	1.1029882227267462	[245]	[464,112,167]	8	hSpCas9	negative selection	1475078
45987642	45987665	21	-	26627737	HeLa	viability after 8 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.49133771172967966	[501]	[238,430,240]	4	hSpCas9	negative selection	1475079
45990246	45990269	21	+	26627737	HeLa	viability after 8 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.737945130310758	[110]	[33,39,14]	-6	hSpCas9	negative selection	1475080
45981891	45981914	21	-	26627737	HeLa	viability after 12 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.0994645168396888	[98]	[117,95,48]	7	hSpCas9	negative selection	1557390
45982742	45982765	21	+	26627737	HeLa	viability after 12 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.9581481597050177	[640]	[246,119,46]	-7	hSpCas9	negative selection	1557391
45984395	45984418	21	+	26627737	HeLa	viability after 12 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.08473567963559447	[1057]	[528,349,525]	0	hSpCas9	negative selection	1557392
45986552	45986575	21	+	26627737	HeLa	viability after 12 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	1.3572222016870388	[245]	[394,262,126]	8	hSpCas9	negative selection	1557393
45987642	45987665	21	-	26627737	HeLa	viability after 12 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	1.3692945639288885	[501]	[817,262,563]	8	hSpCas9	negative selection	1557394
45990246	45990269	21	+	26627737	HeLa	viability after 12 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-4.738087412243295	[110]	[0,2,0]	-9	hSpCas9	negative selection	1557395
45981891	45981914	21	-	26627737	HeLa	viability after 15 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.8796238860087822	[98]	[82,8,134]	6	hSpCas9	negative selection	1639705
45982742	45982765	21	+	26627737	HeLa	viability after 15 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-2.2891694348512983	[640]	[64,65,26]	-9	hSpCas9	negative selection	1639706
45984395	45984418	21	+	26627737	HeLa	viability after 15 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.2136154636210914	[1057]	[284,282,561]	-2	hSpCas9	negative selection	1639707
45986552	45986575	21	+	26627737	HeLa	viability after 15 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.8365677055865853	[245]	[119,253,161]	6	hSpCas9	negative selection	1639708
45987642	45987665	21	-	26627737	HeLa	viability after 15 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	1.232285248117861	[501]	[527,416,495]	8	hSpCas9	negative selection	1639709
45990246	45990269	21	+	26627737	HeLa	viability after 15 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-5.075058506272077	[110]	[0,1,0]	-9	hSpCas9	negative selection	1639710
45981891	45981914	21	-	26627737	HeLa	viability after 18 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.9359985140205858	[98]	[60,7,134]	7	hSpCas9	negative selection	1722020
45982742	45982765	21	+	26627737	HeLa	viability after 18 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-2.307802484247147	[640]	[41,54,26]	-9	hSpCas9	negative selection	1722021
45984395	45984418	21	+	26627737	HeLa	viability after 18 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.25430111294722435	[1057]	[180,221,561]	-2	hSpCas9	negative selection	1722022
45986552	45986575	21	+	26627737	HeLa	viability after 18 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.8082109193953024	[245]	[73,209,161]	6	hSpCas9	negative selection	1722023
45987642	45987665	21	-	26627737	HeLa	viability after 18 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	1.241984073185435	[501]	[351,355,495]	8	hSpCas9	negative selection	1722024
45990246	45990269	21	+	26627737	HeLa	viability after 18 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-4.774400060973828	[110]	[0,1,0]	-9	hSpCas9	negative selection	1722025
45981891	45981914	21	-	26627737	HCT116	viability after 6 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.513676606055335	[402]	[190,34]	3	hSpCas9	negative selection	1804335
45982742	45982765	21	+	26627737	HCT116	viability after 6 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-2.403253294669389	[535]	[42,0]	-8	hSpCas9	negative selection	1804336
45984395	45984418	21	+	26627737	HCT116	viability after 6 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.697012588255603	[1099]	[639,81]	4	hSpCas9	negative selection	1804337
45986552	45986575	21	+	26627737	HCT116	viability after 6 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.6442492736478812	[791]	[98,68]	-4	hSpCas9	negative selection	1804338
45987642	45987665	21	-	26627737	HCT116	viability after 6 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.489528295967125	[1473]	[305,335]	2	hSpCas9	negative selection	1804339
45990246	45990269	21	+	26627737	HCT116	viability after 6 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-4.87763420270007	[186]	[0,0]	-9	hSpCas9	negative selection	1804340
45981891	45981914	21	-	26627737	HCT116	viability after 8 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.2619053380117977	[92]	[70,9,102]	3	hSpCas9	negative selection	1886650
45982742	45982765	21	+	26627737	HCT116	viability after 8 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.16654792573412552	[341]	[194,124,183]	-2	hSpCas9	negative selection	1886651
45984395	45984418	21	+	26627737	HCT116	viability after 8 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.0726694475076457	[668]	[433,352,376]	0	hSpCas9	negative selection	1886652
45986552	45986575	21	+	26627737	HCT116	viability after 8 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.9371725373901874	[478]	[118,139,153]	-8	hSpCas9	negative selection	1886653
45987642	45987665	21	-	26627737	HCT116	viability after 8 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.4399799267417237	[813]	[320,196,471]	-5	hSpCas9	negative selection	1886654
45990246	45990269	21	+	26627737	HCT116	viability after 8 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.940118108526995	[35]	[2,26,0]	-8	hSpCas9	negative selection	1886655
45981891	45981914	21	-	26627737	HCT116	viability after 9 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.5769857051623154	[402]	[207,122]	4	hSpCas9	negative selection	1968965
45982742	45982765	21	+	26627737	HCT116	viability after 9 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.14987212368104988	[535]	[252,30]	-1	hSpCas9	negative selection	1968966
45984395	45984418	21	+	26627737	HCT116	viability after 9 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.3990667426045066	[1099]	[307,449]	3	hSpCas9	negative selection	1968967
45986552	45986575	21	+	26627737	HCT116	viability after 9 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.2107849647668052	[791]	[84,370]	1	hSpCas9	negative selection	1968968
45987642	45987665	21	-	26627737	HCT116	viability after 9 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.54564339665531	[1473]	[645,517]	4	hSpCas9	negative selection	1968969
45990246	45990269	21	+	26627737	HCT116	viability after 9 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-5.0016922872475496	[186]	[0,1]	-9	hSpCas9	negative selection	1968970
45981891	45981914	21	-	26627737	HCT116	viability after 12 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.2373704778302983	[92]	[51,63,233]	8	hSpCas9	negative selection	2051280
45982742	45982765	21	+	26627737	HCT116	viability after 12 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-1.046098607576383	[341]	[134,90,30]	-8	hSpCas9	negative selection	2051281
45984395	45984418	21	+	26627737	HCT116	viability after 12 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.505544369617713	[668]	[311,152,269]	-5	hSpCas9	negative selection	2051282
45986552	45986575	21	+	26627737	HCT116	viability after 12 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.7760122658013897	[478]	[123,186,132]	-7	hSpCas9	negative selection	2051283
45987642	45987665	21	-	26627737	HCT116	viability after 12 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.7010081997100513	[813]	[252,290,246]	-6	hSpCas9	negative selection	2051284
45990246	45990269	21	+	26627737	HCT116	viability after 12 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.7157743929816052	[35]	[7,16,9]	-6	hSpCas9	negative selection	2051285
45981891	45981914	21	-	26627737	HCT116	viability after 15 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.9272973648122301	[92]	[96,92,113]	7	hSpCas9	negative selection	2133595
45982742	45982765	21	+	26627737	HCT116	viability after 15 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.8504981354067154	[341]	[188,77,69]	-7	hSpCas9	negative selection	2133596
45984395	45984418	21	+	26627737	HCT116	viability after 15 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.2352015659540717	[668]	[431,393,167]	-2	hSpCas9	negative selection	2133597
45986552	45986575	21	+	26627737	HCT116	viability after 15 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-1.0044711008945222	[478]	[87,148,167]	-7	hSpCas9	negative selection	2133598
45987642	45987665	21	-	26627737	HCT116	viability after 15 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.34558750680127637	[813]	[213,339,528]	-4	hSpCas9	negative selection	2133599
45990246	45990269	21	+	26627737	HCT116	viability after 15 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	0.45393043811153433	[35]	[13,22,45]	4	hSpCas9	negative selection	2133600
45981891	45981914	21	-	26627737	HCT116	viability after 18 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	0.5836879601184961	[92]	[76,38,88]	5	hSpCas9	negative selection	2215910
45982742	45982765	21	+	26627737	HCT116	viability after 18 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.8123514374552128	[341]	[140,95,42]	-6	hSpCas9	negative selection	2215911
45984395	45984418	21	+	26627737	HCT116	viability after 18 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.3181507220065366	[668]	[209,281,285]	-3	hSpCas9	negative selection	2215912
45986552	45986575	21	+	26627737	HCT116	viability after 18 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.6793348978799433	[478]	[117,153,161]	-6	hSpCas9	negative selection	2215913
45987642	45987665	21	-	26627737	HCT116	viability after 18 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.5275030057205236	[813]	[96,396,318]	-5	hSpCas9	negative selection	2215914
45990246	45990269	21	+	26627737	HCT116	viability after 18 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	0.3301579158146941	[35]	[5,50,5]	3	hSpCas9	negative selection	2215915
45984275	45984298	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	-0.0827355309357813	[3,3]	[2,2]	-1	hSpCas9	positive selection	2980476
45991011	45991034	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	-0.12460527884697385	[3,3]	[2,2]	-2	hSpCas9	positive selection	2980477
45982638	45982661	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	-0.4694847559912523	[2,3]	[3,0]	-6	hSpCas9	positive selection	2980478
45986980	45987003	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.3862587071774143	[4,4]	[3,6]	7	hSpCas9	positive selection	2980479
45984275	45984298	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	-0.09209697435377559	[3,3]	[3,1]	-1	hSpCas9	positive selection	3048334
45991011	45991034	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	-0.09697116066745891	[3,3]	[2,1]	-1	hSpCas9	positive selection	3048335
45982638	45982661	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	-0.18405020105247383	[2,2]	[2,0]	-3	hSpCas9	positive selection	3048336
45986980	45987003	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.6150145424663215	[4,4]	[4,5]	8	hSpCas9	positive selection	3048337
45989080	45989103		+	24336571	A375	resistance to PLX after 7 days	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.11302217579793039	[21,22]	[22,24]	4	hSpCas9	positive selection	3106743
45987145	45987168		+	24336571	A375	resistance to PLX after 7 days	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.6132008196068783	[3,2]	[1,1]	-9	hSpCas9	positive selection	3106744
45989127	45989150		-	24336571	A375	resistance to PLX after 7 days	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	0.07659224471489279	[37,35]	[38,37]	2	hSpCas9	positive selection	3106745
45989080	45989103		+	24336571	A375	resistance to PLX after 14 days	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.4568766988982952	[20,26]	[16,11]	4	hSpCas9	positive selection	3164536
45987145	45987168		+	24336571	A375	resistance to PLX after 14 days	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.49828809546068675	[2,1]	[1,1]	4	hSpCas9	positive selection	3164537
45989127	45989150		-	24336571	A375	resistance to PLX after 14 days	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	-0.061611180254214526	[30,29]	[13,12]	0	hSpCas9	positive selection	3164538
45989080	45989103		+	24336571	A375	viability after 7 days	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.3844483768875149	[17]	[21,22]	6	hSpCas9	negative selection	3222329
45987145	45987168		+	24336571	A375	viability after 7 days	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.5426637380190689	[4]	[3,2]	-6	hSpCas9	negative selection	3222330
45989127	45989150		-	24336571	A375	viability after 7 days	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	0.43273003706479707	[28]	[37,35]	6	hSpCas9	negative selection	3222331
45989080	45989103		+	24336571	A375	viability after 14 days	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.47412786508443827	[17]	[20,26]	6	hSpCas9	negative selection	3280122
45987145	45987168		+	24336571	A375	viability after 14 days	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.8278353001070327	[4]	[2,1]	-7	hSpCas9	negative selection	3280123
45989127	45989150		-	24336571	A375	viability after 14 days	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	0.18805757763947573	[28]	[30,29]	2	hSpCas9	negative selection	3280124
45990271	45990294	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	-0.08198528502890845	[610,684]	[0,6]	0	hSpCas9	positive selection	3344058
45989080	45989103	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	4.826003628579501	[99,104]	[0,36]	9	hSpCas9	positive selection	3344059
45990254	45990277	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	1.9719239925835867	[38,38]	[0,0]	7	hSpCas9	positive selection	3363284
45989108	45989131	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	-1.147815251690509	[338,338]	[0,0]	-7	hSpCas9	positive selection	3363285
45989108	45989131	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	3.7978945928085377	[10,10]	[0,0]	9	hSpCas9	positive selection	3363286
45984275	45984298	21	-	26780180	HT29	viability (Avana library 4 designs)	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	-0.0790872202804892	[]	[]	-1	hSpCas9	negative selection	3416929
45991011	45991034	21	-	26780180	HT29	viability (Avana library 4 designs)	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	-0.0795410850165339	[]	[]	-1	hSpCas9	negative selection	3416930
45982638	45982661	21	-	26780180	HT29	viability (Avana library 4 designs)	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	1.21238682902951	[]	[]	5	hSpCas9	negative selection	3416931
45986979	45987002	21	+	26780180	HT29	viability (Avana library 4 designs)	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.792704470023438	[]	[]	3	hSpCas9	negative selection	3416932
45982638	45982661	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	4.67391458351636	[]	[]	7	hSpCas9	negative selection	3494695
45986979	45987002	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	2.73468143545805	[]	[]	4	hSpCas9	negative selection	3494696
45991011	45991034	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	0.14892816805548	[]	[]	0	hSpCas9	negative selection	3494697
45984275	45984298	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	4.34338053631063	[]	[]	7	hSpCas9	negative selection	3494698
45982623	45982646	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	3.59368783027741	[]	[]	6	hSpCas9	negative selection	3494699
45984371	45984394	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGACGCACTCAAAAGCAGCGTGG	COL6A1	ENSG00000142156	2.70588412212796	[]	[]	4	hSpCas9	negative selection	3494700
45982638	45982661	21	-	26780180	A375	viability (Avana lentiGuide)	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	-9.28836709813357	[]	[]	-9	hSpCas9	negative selection	3603354
45986979	45987002	21	+	26780180	A375	viability (Avana lentiGuide)	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-2.16805923760144	[]	[]	-4	hSpCas9	negative selection	3603355
45991011	45991034	21	-	26780180	A375	viability (Avana lentiGuide)	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	1.3575835391524	[]	[]	1	hSpCas9	negative selection	3603356
45984275	45984298	21	-	26780180	A375	viability (Avana lentiGuide)	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	-2.46014020296824	[]	[]	-4	hSpCas9	negative selection	3603357
45982623	45982646	21	+	26780180	A375	viability (Avana lentiGuide)	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	-1.63718204967771	[]	[]	-3	hSpCas9	negative selection	3603358
45984371	45984394	21	+	26780180	A375	viability (Avana lentiGuide)	CGACGCACTCAAAAGCAGCGTGG	COL6A1	ENSG00000142156	-7.59703636487041	[]	[]	-9	hSpCas9	negative selection	3603359
45982638	45982661	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	-0.024557579449524858	[3]	[3,3]	0	hSpCas9	positive selection	3712013
45986979	45987002	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.000708322333201894	[5]	[5,4]	0	hSpCas9	positive selection	3712014
45991011	45991034	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	0.029464722237405566	[4]	[4,4]	0	hSpCas9	positive selection	3712015
45984275	45984298	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	0.3899174559394288	[4]	[5,7]	9	hSpCas9	positive selection	3712016
45982623	45982646	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.358154371324944	[4]	[5,5]	9	hSpCas9	positive selection	3712017
45984371	45984394	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGACGCACTCAAAAGCAGCGTGG	COL6A1	ENSG00000142156	-0.3190768403267135	[3]	[2,3]	-5	hSpCas9	positive selection	3712018
45982638	45982661	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAAAGAACAGGTCCACGGGG	COL6A1	ENSG00000142156	0.17417622807911634	[4]	[2,4]	4	hSpCas9	positive selection	3820620
45986979	45987002	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.05703923138404621	[6]	[6,4]	-1	hSpCas9	positive selection	3820621
45991011	45991034	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCAGTCCAAAGGCACCGGGG	COL6A1	ENSG00000142156	0.06460869773041111	[5]	[5,4]	1	hSpCas9	positive selection	3820622
45984275	45984298	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCAGGTTTCGGTCACAGCGG	COL6A1	ENSG00000142156	0.29181746881659265	[5]	[5,5]	7	hSpCas9	positive selection	3820623
45982623	45982646	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.20286253246125724	[5]	[5,4]	5	hSpCas9	positive selection	3820624
45984371	45984394	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGACGCACTCAAAAGCAGCGTGG	COL6A1	ENSG00000142156	0.1650616523718768	[4]	[4,3]	4	hSpCas9	positive selection	3820625
45990271	45990294	21	-	26780180	A375	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.290096542436597	[]	[]	0	hSpCas9	negative selection	3928623
45989108	45989131	21	+	26780180	A375	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	1.45623830826067	[]	[]	8	hSpCas9	negative selection	3928624
45989080	45989103	21	+	26780180	A375	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	1.34622646018648	[]	[]	7	hSpCas9	negative selection	3928625
45989108	45989131	21	-	26780180	A375	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	1.07756028299445	[]	[]	5	hSpCas9	negative selection	3928626
45987145	45987168	21	+	26780180	A375	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0	[]	[]	0	hSpCas9	negative selection	3928627
45990254	45990277	21	+	26780180	A375	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	1.3807819309232	[]	[]	7	hSpCas9	negative selection	3928628
45990271	45990294	21	-	26780180	HT29	viability (GeCKOv2 library)	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	-0.0877655189478727	[]	[]	-3	hSpCas9	negative selection	4036589
45989108	45989131	21	+	26780180	HT29	viability (GeCKOv2 library)	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	1.3467237069948	[]	[]	6	hSpCas9	negative selection	4036590
45989080	45989103	21	+	26780180	HT29	viability (GeCKOv2 library)	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	1.61895086416131	[]	[]	8	hSpCas9	negative selection	4036591
45989108	45989131	21	-	26780180	HT29	viability (GeCKOv2 library)	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.787048543849406	[]	[]	3	hSpCas9	negative selection	4036592
45987145	45987168	21	+	26780180	HT29	viability (GeCKOv2 library)	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0	[]	[]	0	hSpCas9	negative selection	4036593
45990254	45990277	21	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	1.96020323569098	[]	[]	9	hSpCas9	negative selection	4036594
45989080	45989103	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.12127725192800093	[4]	[2,3]	3	hSpCas9	positive selection	4128944
45987145	45987168	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.593962393780334	[0]	[0,0]	9	hSpCas9	positive selection	4128945
45989127	45989150	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	-0.005384441860207589	[5]	[3,3]	0	hSpCas9	positive selection	4128946
45989080	45989103	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.8531007118650549	[4]	[1,1,4,3]	5	hSpCas9	positive selection	4192966
45987145	45987168	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.13877149985010465	[2]	[0,2,1,0]	1	hSpCas9	positive selection	4192967
45989127	45989150	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGGCACTCACAGGATCTCCGG	COL6A1	ENSG00000142156	-0.005805110619236442	[4]	[1,3,2,0]	0	hSpCas9	positive selection	4192968
45990271	45990294	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3883461209221928	[5]	[5,5]	7	hSpCas9	positive selection	4264292
45989080	45989103	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	-0.40317206780292153	[2]	[1,0]	-7	hSpCas9	positive selection	4264293
45987145	45987168	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.3628918518378901	[0]	[0,0]	7	hSpCas9	positive selection	4264294
45990254	45990277	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.2413930868803016	[2]	[0,0]	-9	hSpCas9	positive selection	4328563
45989108	45989131	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	-0.18653049439708402	[3]	[2,1]	-4	hSpCas9	positive selection	4328564
45989108	45989131	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.765582966581015	[1]	[0,0]	-9	hSpCas9	positive selection	4328565
45982737	45982759	21	+	27760321	OCIAML3	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.055044024254865986	[1097,918]	[760,887]	0	hSpCas9	negative selection	4390914
45990387	45990409	21	+	27760321	OCIAML3	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.8363859149366867	[594,474]	[169,314]	-7	hSpCas9	negative selection	4390915
45984426	45984448	21	+	27760321	OCIAML3	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.11895446141506394	[367,302]	[257,316]	1	hSpCas9	negative selection	4390916
45997432	45997454	21	-	27760321	OCIAML3	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	-0.21510843614545372	[225,224]	[131,178]	-2	hSpCas9	negative selection	4390917
45986966	45986988	21	-	27760321	OCIAML3	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.5536726012389621	[1191,945]	[1081,1398]	6	hSpCas9	negative selection	4390918
45982737	45982759	21	+	27760321	OCIAML2	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.01848601165614805	[1097,918]	[731,942]	0	hSpCas9	negative selection	4474377
45990387	45990409	21	+	27760321	OCIAML2	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.3007565624711801	[594,474]	[350,346]	-4	hSpCas9	negative selection	4474378
45984426	45984448	21	+	27760321	OCIAML2	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	-0.023047319105357178	[367,302]	[223,320]	0	hSpCas9	negative selection	4474379
45997432	45997454	21	-	27760321	OCIAML2	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	-0.42505657345315695	[225,224]	[93,191]	-5	hSpCas9	negative selection	4474380
45986966	45986988	21	-	27760321	OCIAML2	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.7336528247531986	[1191,945]	[1221,1701]	8	hSpCas9	negative selection	4474381
45982737	45982759	21	+	27760321	MV411	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.4670857953315355	[1097,918]	[751,1162]	3	hSpCas9	negative selection	4557840
45990387	45990409	21	+	27760321	MV411	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.1870565209841708	[594,474]	[161,527]	-1	hSpCas9	negative selection	4557841
45984426	45984448	21	+	27760321	MV411	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	-0.5571724946136749	[367,302]	[108,210]	-4	hSpCas9	negative selection	4557842
45997432	45997454	21	-	27760321	MV411	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.03979923100043603	[225,224]	[206,72]	0	hSpCas9	negative selection	4557843
45986966	45986988	21	-	27760321	MV411	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	-0.10629126093700214	[1191,945]	[520,846]	-1	hSpCas9	negative selection	4557844
45982737	45982759	21	+	27760321	HL60	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.5658651489933659	[1097,918]	[1217,1210]	6	hSpCas9	negative selection	4641303
45990387	45990409	21	+	27760321	HL60	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.1729239290142232	[594,474]	[380,389]	-2	hSpCas9	negative selection	4641304
45984426	45984448	21	+	27760321	HL60	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	-0.229161298548272	[367,302]	[239,224]	-3	hSpCas9	negative selection	4641305
45997432	45997454	21	-	27760321	HL60	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	-0.47699590935673897	[225,224]	[74,193]	-5	hSpCas9	negative selection	4641306
45986966	45986988	21	-	27760321	HL60	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	-0.28571558466455704	[1191,945]	[626,801]	-3	hSpCas9	negative selection	4641307
45982737	45982759	21	+	27760321	HT1080	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	-0.3610682169564541	[918,716]	[215,294]	-2	hSpCas9	negative selection	4724766
45990387	45990409	21	+	27760321	HT1080	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.6650075825464656	[474,370]	[185,18]	-3	hSpCas9	negative selection	4724767
45984426	45984448	21	+	27760321	HT1080	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.9316581002266642	[302,236]	[261,142]	5	hSpCas9	negative selection	4724768
45997432	45997454	21	-	27760321	HT1080	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	3.623285023264214	[224,175]	[792,1193]	9	hSpCas9	negative selection	4724769
45986966	45986988	21	-	27760321	HT1080	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	-1.6380085528792139	[945,737]	[123,89]	-5	hSpCas9	negative selection	4724770
45982737	45982759	21	+	27760321	HT29	viability after 7 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.2750196447243496	[918,716]	[1273,1204,1334]	4	hSpCas9	negative selection	4808229
45990387	45990409	21	+	27760321	HT29	viability after 7 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	0.326163443580767	[474,370]	[741,751,562]	5	hSpCas9	negative selection	4808230
45984426	45984448	21	+	27760321	HT29	viability after 7 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.026548162978446255	[302,236]	[392,318,353]	0	hSpCas9	negative selection	4808231
45997432	45997454	21	-	27760321	HT29	viability after 7 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	-0.4237189845580934	[224,175]	[279,152,156]	-6	hSpCas9	negative selection	4808232
45986966	45986988	21	-	27760321	HT29	viability after 7 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.2717373868993227	[945,737]	[1431,1112,1388]	4	hSpCas9	negative selection	4808233
45982737	45982759	21	+	27760321	HT29	viability after 25 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.544715500214564	[918,716]	[1154,1634,1305]	6	hSpCas9	negative selection	4891692
45990387	45990409	21	+	27760321	HT29	viability after 25 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	0.49512817876339343	[474,370]	[456,963,630]	5	hSpCas9	negative selection	4891693
45984426	45984448	21	+	27760321	HT29	viability after 25 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.8389800977387389	[302,236]	[480,382,823]	8	hSpCas9	negative selection	4891694
45997432	45997454	21	-	27760321	HT29	viability after 25 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.4227834095118578	[224,175]	[136,339,471]	4	hSpCas9	negative selection	4891695
45986966	45986988	21	-	27760321	HT29	viability after 25 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.8871350662872208	[945,737]	[1493,2030,1834]	8	hSpCas9	negative selection	4891696
45982737	45982759	21	+	27760321	HT29	viability after 22 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.47995911115407264	[918,716]	[1415,1316,1219]	5	hSpCas9	negative selection	4975155
45990387	45990409	21	+	27760321	HT29	viability after 22 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	0.1380543284535343	[474,370]	[494,536,583]	1	hSpCas9	negative selection	4975156
45984426	45984448	21	+	27760321	HT29	viability after 22 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.599483473745839	[302,236]	[639,245,528]	6	hSpCas9	negative selection	4975157
45997432	45997454	21	-	27760321	HT29	viability after 22 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.1303778990839184	[224,175]	[152,351,258]	1	hSpCas9	negative selection	4975158
45986966	45986988	21	-	27760321	HT29	viability after 22 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.8237186519210793	[945,737]	[1583,1567,2022]	8	hSpCas9	negative selection	4975159
45982737	45982759	21	+	27760321	HT29	viability after 19 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.8355989929386194	[918,716]	[1757,1973,1298]	8	hSpCas9	negative selection	5058618
45990387	45990409	21	+	27760321	HT29	viability after 19 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.12371155068139117	[474,370]	[615,374,361]	-1	hSpCas9	negative selection	5058619
45984426	45984448	21	+	27760321	HT29	viability after 19 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	-0.670710354299183	[302,236]	[232,239,115]	-5	hSpCas9	negative selection	5058620
45997432	45997454	21	-	27760321	HT29	viability after 19 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.08733270475711974	[224,175]	[272,220,239]	0	hSpCas9	negative selection	5058621
45986966	45986988	21	-	27760321	HT29	viability after 19 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.7404176688116166	[945,737]	[1552,1540,1720]	7	hSpCas9	negative selection	5058622
45982737	45982759	21	+	27760321	HT29	viability after 16 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.48479125401831547	[918,716]	[1018,1512,1278]	5	hSpCas9	negative selection	5142081
45990387	45990409	21	+	27760321	HT29	viability after 16 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	0.5812944001303934	[474,370]	[837,726,570]	6	hSpCas9	negative selection	5142082
45984426	45984448	21	+	27760321	HT29	viability after 16 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	-0.08205358430824611	[302,236]	[217,163,470]	-1	hSpCas9	negative selection	5142083
45997432	45997454	21	-	27760321	HT29	viability after 16 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.05988776401415952	[224,175]	[166,165,363]	0	hSpCas9	negative selection	5142084
45986966	45986988	21	-	27760321	HT29	viability after 16 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.6890492344707919	[945,737]	[1466,1711,1366]	7	hSpCas9	negative selection	5142085
45982737	45982759	21	+	27760321	HT29	viability after 13 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.786880755640615	[918,716]	[1943,1742,1247]	9	hSpCas9	negative selection	5225544
45990387	45990409	21	+	27760321	HT29	viability after 13 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	0.43872591958587226	[474,370]	[448,917,630]	5	hSpCas9	negative selection	5225545
45984426	45984448	21	+	27760321	HT29	viability after 13 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.15421057455397563	[302,236]	[196,344,494]	2	hSpCas9	negative selection	5225546
45997432	45997454	21	-	27760321	HT29	viability after 13 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.11751969766849424	[224,175]	[166,298,288]	1	hSpCas9	negative selection	5225547
45986966	45986988	21	-	27760321	HT29	viability after 13 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.7556365735116639	[945,737]	[1789,1662,1502]	8	hSpCas9	negative selection	5225548
45982737	45982759	21	+	27760321	HT29	viability after 10 days	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	0.37899184679261744	[918,716]	[1342,1678,979]	5	hSpCas9	negative selection	5309007
45990387	45990409	21	+	27760321	HT29	viability after 10 days	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.06769891932198244	[474,370]	[460,647,408]	-1	hSpCas9	negative selection	5309008
45984426	45984448	21	+	27760321	HT29	viability after 10 days	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	0.5321509034775902	[302,236]	[385,400,668]	7	hSpCas9	negative selection	5309009
45997432	45997454	21	-	27760321	HT29	viability after 10 days	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.677448877282828	[224,175]	[456,250,486]	8	hSpCas9	negative selection	5309010
45986966	45986988	21	-	27760321	HT29	viability after 10 days	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	0.8051886885681605	[945,737]	[2038,2016,1467]	9	hSpCas9	negative selection	5309011
45982737	45982759	21	+	27760321	MOLM13	viability	GCGCTTCATCGACAACCTGAGG	COL6A1	ENSG00000142156	1.294905361855858	[1097,918]	[2015,857]	8	hSpCas9	negative selection	5392470
45990387	45990409	21	+	27760321	MOLM13	viability	GGCAAGCGTGGCATCGACGGGG	COL6A1	ENSG00000142156	-0.6464234398935198	[594,474]	[141,233]	-4	hSpCas9	negative selection	5392471
45984426	45984448	21	+	27760321	MOLM13	viability	ACCGACTGCGCTATCAAGAAGG	COL6A1	ENSG00000142156	1.1614577308167977	[367,302]	[798,99]	7	hSpCas9	negative selection	5392472
45997432	45997454	21	-	27760321	MOLM13	viability	GTAGCCTTTAGGTCCGATAGGG	COL6A1	ENSG00000142156	0.37363989977464596	[225,224]	[274,71]	2	hSpCas9	negative selection	5392473
45986966	45986988	21	-	27760321	MOLM13	viability	CGCCGGTACGTGTGGTCCGTGG	COL6A1	ENSG00000142156	-0.0772193822304943	[1191,945]	[538,592]	0	hSpCas9	negative selection	5392474
45982117	45982140	21	+	27661255	K562	viability	GCCTTGGCCGGGGCCCCTAGAGG	COL6A1	ENSG00000142156	0.42999986467249585	[160,359]	[296,258]	9	dCas9-KRAB	negative selection	5472092
45982169	45982192	21	+	27661255	K562	viability	GACCGCAGGCAGCTCGGGAGGGG	COL6A1	ENSG00000142156	0.15832312577517618	[506,680]	[543,511]	5	dCas9-KRAB	negative selection	5472093
45981814	45981837	21	-	27661255	K562	viability	GTCACCACACAGCGCGGCCAGGG	COL6A1	ENSG00000142156	0.07909339885178301	[998,1044]	[980,759]	2	dCas9-KRAB	negative selection	5472094
45981979	45982002	21	-	27661255	K562	viability	GGCCGGCAGCAAAGAGCGGGGGG	COL6A1	ENSG00000142156	0.05936261893321704	[1183,992]	[1011,820]	2	dCas9-KRAB	negative selection	5472095
45982194	45982217	21	-	27661255	K562	viability	GCACCAGCTCCCCCTCGCCAGGG	COL6A1	ENSG00000142156	-0.09798811143034558	[585,698]	[504,454]	-4	dCas9-KRAB	negative selection	5472096
45990271	45990294	21	-	27260156	BXPC3	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.35628884495207336	[2157]	[2857,2581,2966,3185]	7	hSpCas9	negative selection	5536752
45989080	45989103	21	+	27260156	BXPC3	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.4564981683949866	[271]	[449,324,336,449]	8	hSpCas9	negative selection	5536753
45987145	45987168	21	+	27260156	BXPC3	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.06171780769732926	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	5536754
45990254	45990277	21	+	27260156	BXPC3	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.1855012010304165	[204]	[69,46,57,221]	-9	hSpCas9	negative selection	5601023
45989108	45989131	21	-	27260156	BXPC3	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.004425338367597731	[782]	[734,675,842,1074]	0	hSpCas9	negative selection	5601024
45989108	45989131	21	+	27260156	BXPC3	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.47542164787642305	[172]	[143,101,150,121]	-8	hSpCas9	negative selection	5601025
45990271	45990294	21	-	27260156	A673	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.31611296192438854	[2157]	[3574,2984,3048,3342]	7	hSpCas9	negative selection	5658003
45989080	45989103	21	+	27260156	A673	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.3915875989578475	[271]	[331,314,436,631]	8	hSpCas9	negative selection	5658004
45987145	45987168	21	+	27260156	A673	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.2631622979798074	[0]	[0,0,0,0]	-6	hSpCas9	negative selection	5658005
45990254	45990277	21	+	27260156	A673	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.5563992176181791	[204]	[184,169,211,99]	-8	hSpCas9	negative selection	5722274
45989108	45989131	21	-	27260156	A673	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.23475138935841977	[782]	[1254,1058,1067,1056]	5	hSpCas9	negative selection	5722275
45989108	45989131	21	+	27260156	A673	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.7681177819673968	[172]	[85,83,145,170]	-9	hSpCas9	negative selection	5722276
45990271	45990294	21	-	27260156	A375	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.35558138415106244	[2157]	[3354,3528,3018,3048]	5	hSpCas9	negative selection	5779254
45989080	45989103	21	+	27260156	A375	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.7557142902912869	[271]	[581,450,700,412]	9	hSpCas9	negative selection	5779255
45987145	45987168	21	+	27260156	A375	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.22260698094002684	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	5779256
45990254	45990277	21	+	27260156	A375	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.378698850910955	[204]	[37,22,103,18]	-9	hSpCas9	negative selection	5843525
45989108	45989131	21	-	27260156	A375	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.1469410057475946	[782]	[1175,873,1285,726]	2	hSpCas9	negative selection	5843526
45989108	45989131	21	+	27260156	A375	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-2.7531554212945166	[172]	[25,52,32,12]	-9	hSpCas9	negative selection	5843527
45990271	45990294	21	-	27260156	COLO741	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.36349217347164986	[2157]	[4262,3296,3162]	7	hSpCas9	negative selection	5900505
45989080	45989103	21	+	27260156	COLO741	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.16537787783543123	[271]	[357,337,463]	3	hSpCas9	negative selection	5900506
45987145	45987168	21	+	27260156	COLO741	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.3524737808476335	[0]	[0,0,0]	-6	hSpCas9	negative selection	5900507
45990254	45990277	21	+	27260156	COLO741	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.7786224709751077	[204]	[186,154,120]	-9	hSpCas9	negative selection	5964776
45989108	45989131	21	-	27260156	COLO741	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.34498721172850233	[782]	[1447,1175,1204]	7	hSpCas9	negative selection	5964777
45989108	45989131	21	+	27260156	COLO741	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.8416364653110397	[172]	[138,107,123]	-9	hSpCas9	negative selection	5964778
45990271	45990294	21	-	27260156	CAL120	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.4985520872287168	[2157]	[3399,3910,4005]	7	hSpCas9	negative selection	6021756
45989080	45989103	21	+	27260156	CAL120	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.20610105432300818	[271]	[333,510,318]	3	hSpCas9	negative selection	6021757
45987145	45987168	21	+	27260156	CAL120	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.31522623407729533	[0]	[0,0,0]	-4	hSpCas9	negative selection	6021758
45990254	45990277	21	+	27260156	CAL120	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.5977581029618728	[204]	[146,72,42]	-9	hSpCas9	negative selection	6086027
45989108	45989131	21	-	27260156	CAL120	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.2316518835446323	[782]	[1474,1168,842]	3	hSpCas9	negative selection	6086028
45989108	45989131	21	+	27260156	CAL120	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.2136844688185358	[172]	[162,89,36]	-9	hSpCas9	negative selection	6086029
45990271	45990294	21	-	27260156	CADOES1	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.4269889015745698	[2157]	[2615,2760,2634,2784]	7	hSpCas9	negative selection	6143007
45989080	45989103	21	+	27260156	CADOES1	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.6036306774253981	[271]	[301,495,331,408]	8	hSpCas9	negative selection	6143008
45987145	45987168	21	+	27260156	CADOES1	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.1046074123573355	[0]	[0,0,0,0]	1	hSpCas9	negative selection	6143009
45990254	45990277	21	+	27260156	CADOES1	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.2454551859626843	[204]	[120,60,97,39]	-9	hSpCas9	negative selection	6207278
45989108	45989131	21	-	27260156	CADOES1	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.2396806805270859	[782]	[1070,822,756,784]	4	hSpCas9	negative selection	6207279
45989108	45989131	21	+	27260156	CADOES1	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.0610316833452682	[172]	[31,140,76,57]	-9	hSpCas9	negative selection	6207280
45990271	45990294	21	-	27260156	EWS502	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.5291719337482332	[2157]	[3186,2674,3457,3948]	8	hSpCas9	negative selection	6264258
45989080	45989103	21	+	27260156	EWS502	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.5583150104984986	[271]	[337,350,471,557]	8	hSpCas9	negative selection	6264259
45987145	45987168	21	+	27260156	EWS502	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.08156866895534698	[0]	[0,0,0,0]	-1	hSpCas9	negative selection	6264260
45990254	45990277	21	+	27260156	EWS502	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.625199651244037	[204]	[58,49,119,53]	-9	hSpCas9	negative selection	6328529
45989108	45989131	21	-	27260156	EWS502	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.22857989467243078	[782]	[916,862,1137,978]	4	hSpCas9	negative selection	6328530
45989108	45989131	21	+	27260156	EWS502	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.872658862475498	[172]	[76,60,33,21]	-9	hSpCas9	negative selection	6328531
45990271	45990294	21	-	27260156	EW8	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.24973272694646553	[2157]	[2622,2110,1779,1908]	4	hSpCas9	negative selection	6385509
45989080	45989103	21	+	27260156	EW8	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.4423583415780356	[271]	[438,267,243,270]	7	hSpCas9	negative selection	6385510
45987145	45987168	21	+	27260156	EW8	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.30430985650646214	[0]	[0,0,0,0]	5	hSpCas9	negative selection	6385511
45990254	45990277	21	+	27260156	EW8	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.3086306954039089	[204]	[60,78,45,84]	-9	hSpCas9	negative selection	6449780
45989108	45989131	21	-	27260156	EW8	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.13355566347111036	[782]	[913,825,545,546]	2	hSpCas9	negative selection	6449781
45989108	45989131	21	+	27260156	EW8	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.5660783563458573	[172]	[80,82,51,167]	-8	hSpCas9	negative selection	6449782
45990271	45990294	21	-	27260156	CORL105	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3679771869301107	[2157]	[3181,3230,3568,3104]	7	hSpCas9	negative selection	6506760
45989080	45989103	21	+	27260156	CORL105	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.22851600524706417	[271]	[425,364,470,247]	4	hSpCas9	negative selection	6506761
45987145	45987168	21	+	27260156	CORL105	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.22721281181091513	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6506762
45990254	45990277	21	+	27260156	CORL105	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.9831672385414778	[204]	[118,116,167,88]	-9	hSpCas9	negative selection	6571031
45989108	45989131	21	-	27260156	CORL105	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.06725711721260108	[782]	[1090,898,1052,818]	1	hSpCas9	negative selection	6571032
45989108	45989131	21	+	27260156	CORL105	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.3117014502204847	[172]	[97,105,52,64]	-9	hSpCas9	negative selection	6571033
45990271	45990294	21	-	27260156	HS294T	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.4155601668022615	[2157]	[1422,925,1047,1009]	5	hSpCas9	negative selection	6628011
45989080	45989103	21	+	27260156	HS294T	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.6760539732518984	[271]	[130,269,115,151]	8	hSpCas9	negative selection	6628012
45987145	45987168	21	+	27260156	HS294T	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	1.3721219085074186	[0]	[0,0,0,0]	9	hSpCas9	negative selection	6628013
45990254	45990277	21	+	27260156	HS294T	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.3070394859151733	[204]	[36,8,46,35]	-9	hSpCas9	negative selection	6692282
45989108	45989131	21	-	27260156	HS294T	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	-0.39654937321438016	[782]	[194,198,217,327]	-5	hSpCas9	negative selection	6692283
45989108	45989131	21	+	27260156	HS294T	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.0045472242627405	[172]	[28,26,38,39]	-8	hSpCas9	negative selection	6692284
45990271	45990294	21	-	27260156	HCC44	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3480864495435765	[2157]	[3254,2716,3417,3132]	5	hSpCas9	negative selection	6749262
45989080	45989103	21	+	27260156	HCC44	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.5472495156041826	[271]	[406,286,591,548]	8	hSpCas9	negative selection	6749263
45987145	45987168	21	+	27260156	HCC44	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.17453351620550883	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	6749264
45990254	45990277	21	+	27260156	HCC44	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.7491730197779585	[204]	[96,33,96,59]	-9	hSpCas9	negative selection	6813533
45989108	45989131	21	-	27260156	HCC44	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.3896677609680993	[782]	[1054,1414,1030,1064]	6	hSpCas9	negative selection	6813534
45989108	45989131	21	+	27260156	HCC44	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.6532659883227212	[172]	[66,158,68,179]	-7	hSpCas9	negative selection	6813535
45990271	45990294	21	-	27260156	G402	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.27298357610227164	[2157]	[2739,3153,2830,3888]	3	hSpCas9	negative selection	6870513
45989080	45989103	21	+	27260156	G402	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	1.323322813776882	[271]	[1148,738,691,781]	9	hSpCas9	negative selection	6870514
45987145	45987168	21	+	27260156	G402	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.28565990241013317	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	6870515
45990254	45990277	21	+	27260156	G402	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.3788108699409074	[204]	[14,127,20,28]	-9	hSpCas9	negative selection	6934784
45989108	45989131	21	-	27260156	G402	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.33684625476425356	[782]	[1333,1373,698,1431]	4	hSpCas9	negative selection	6934785
45989108	45989131	21	+	27260156	G402	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.5682871836241907	[172]	[97,132,54,8]	-9	hSpCas9	negative selection	6934786
45990271	45990294	21	-	27260156	L33	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.23278216210618785	[2157]	[2507,1015,1511,2747]	5	hSpCas9	negative selection	6991764
45989080	45989103	21	+	27260156	L33	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.43711687919567793	[271]	[413,162,197,344]	8	hSpCas9	negative selection	6991765
45987145	45987168	21	+	27260156	L33	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.5883332593072037	[0]	[0,0,0,0]	9	hSpCas9	negative selection	6991766
45990254	45990277	21	+	27260156	L33	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.19171121821239567	[204]	[214,45,108,215]	-4	hSpCas9	negative selection	7056035
45989108	45989131	21	-	27260156	L33	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.28134818223082225	[782]	[785,441,646,916]	6	hSpCas9	negative selection	7056036
45989108	45989131	21	+	27260156	L33	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.38888143042053236	[172]	[153,54,73,121]	-7	hSpCas9	negative selection	7056037
45990271	45990294	21	-	27260156	K562	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.45273509784182764	[2157]	[3178,2362,2539,2443]	6	hSpCas9	negative selection	7113015
45989080	45989103	21	+	27260156	K562	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.6092833073878497	[271]	[247,490,200,510]	7	hSpCas9	negative selection	7113016
45987145	45987168	21	+	27260156	K562	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.1738498320762858	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7113017
45990254	45990277	21	+	27260156	K562	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-3.295184510527868	[204]	[25,36,6,6]	-9	hSpCas9	negative selection	7177286
45989108	45989131	21	-	27260156	K562	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	-0.03765287134383577	[782]	[712,707,785,520]	0	hSpCas9	negative selection	7177287
45989108	45989131	21	+	27260156	K562	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-4.130242504529511	[172]	[5,13,14,0]	-9	hSpCas9	negative selection	7177288
45990271	45990294	21	-	27260156	HT29	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.33156129834540193	[2157]	[3530,3968,3259,2584]	6	hSpCas9	negative selection	7234266
45989080	45989103	21	+	27260156	HT29	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.33609197135915286	[271]	[545,456,395,295]	6	hSpCas9	negative selection	7234267
45987145	45987168	21	+	27260156	HT29	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.27901894800515237	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	7234268
45990254	45990277	21	+	27260156	HT29	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.885065292889508	[204]	[65,50,17,6]	-9	hSpCas9	negative selection	7298537
45989108	45989131	21	-	27260156	HT29	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.15425343200137775	[782]	[1205,998,1084,957]	3	hSpCas9	negative selection	7298538
45989108	45989131	21	+	27260156	HT29	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.799671795561646	[172]	[101,82,15,46]	-9	hSpCas9	negative selection	7298539
45990271	45990294	21	-	27260156	MHHES1	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.32265304712589815	[2157]	[3323,3374,3375,2266]	6	hSpCas9	negative selection	7355517
45989080	45989103	21	+	27260156	MHHES1	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.30264549062015117	[271]	[482,306,436,299]	5	hSpCas9	negative selection	7355518
45987145	45987168	21	+	27260156	MHHES1	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.1630968580950416	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	7355519
45990254	45990277	21	+	27260156	MHHES1	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.4511949150868106	[204]	[75,101,101,61]	-9	hSpCas9	negative selection	7419788
45989108	45989131	21	-	27260156	MHHES1	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.06198839893598562	[782]	[1125,859,991,743]	1	hSpCas9	negative selection	7419789
45989108	45989131	21	+	27260156	MHHES1	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.5419279953920069	[172]	[13,65,72,98]	-9	hSpCas9	negative selection	7419790
45990271	45990294	21	-	27260156	MEWO	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.2776885271780314	[2157]	[2863,2354,2203]	6	hSpCas9	negative selection	7476768
45989080	45989103	21	+	27260156	MEWO	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.26317306852139244	[271]	[243,351,307]	6	hSpCas9	negative selection	7476769
45987145	45987168	21	+	27260156	MEWO	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.09620936660807722	[0]	[0,0,0]	2	hSpCas9	negative selection	7476770
45990254	45990277	21	+	27260156	MEWO	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.9548712414225993	[204]	[88,73,131]	-9	hSpCas9	negative selection	7541039
45989108	45989131	21	-	27260156	MEWO	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.24329657053756915	[782]	[1181,690,789]	5	hSpCas9	negative selection	7541040
45989108	45989131	21	+	27260156	MEWO	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.9922659988982576	[172]	[106,87,53]	-9	hSpCas9	negative selection	7541041
45990271	45990294	21	-	27260156	LNCAPCLONEFGC	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3013292620715724	[2157]	[2283,2532,2501,2322]	5	hSpCas9	negative selection	7598019
45989080	45989103	21	+	27260156	LNCAPCLONEFGC	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.5243126492072958	[271]	[283,415,316,391]	7	hSpCas9	negative selection	7598020
45987145	45987168	21	+	27260156	LNCAPCLONEFGC	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.14289828313858877	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7598021
45990254	45990277	21	+	27260156	LNCAPCLONEFGC	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.6844844813113664	[204]	[32,70,86,43]	-9	hSpCas9	negative selection	7662290
45989108	45989131	21	-	27260156	LNCAPCLONEFGC	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.21646567659193539	[782]	[834,705,975,808]	3	hSpCas9	negative selection	7662291
45989108	45989131	21	+	27260156	LNCAPCLONEFGC	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.6931249460945677	[172]	[52,48,36,52]	-9	hSpCas9	negative selection	7662292
45990271	45990294	21	-	27260156	PANC0327	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3896968365580409	[2157]	[2361,2439,2558,2680]	6	hSpCas9	negative selection	7719270
45989080	45989103	21	+	27260156	PANC0327	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.6006779497653076	[271]	[400,483,259,307]	8	hSpCas9	negative selection	7719271
45987145	45987168	21	+	27260156	PANC0327	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.17097580133514256	[0]	[0,0,0,0]	2	hSpCas9	negative selection	7719272
45990254	45990277	21	+	27260156	PANC0327	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.76858942582067	[204]	[31,5,34,36]	-9	hSpCas9	negative selection	7783541
45989108	45989131	21	-	27260156	PANC0327	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.26341180738623626	[782]	[1240,628,745,782]	4	hSpCas9	negative selection	7783542
45989108	45989131	21	+	27260156	PANC0327	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.8325011549265602	[172]	[21,41,49,56]	-9	hSpCas9	negative selection	7783543
45990271	45990294	21	-	27260156	NCIH2009	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.5689746815654053	[2157]	[5458,4340,3807]	7	hSpCas9	negative selection	7840521
45989080	45989103	21	+	27260156	NCIH2009	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.38843844941085603	[271]	[578,420,508]	5	hSpCas9	negative selection	7840522
45987145	45987168	21	+	27260156	NCIH2009	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.4816251237464222	[0]	[0,0,0]	-6	hSpCas9	negative selection	7840523
45990254	45990277	21	+	27260156	NCIH2009	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.3198367724259397	[204]	[145,30,12]	-9	hSpCas9	negative selection	7904792
45989108	45989131	21	-	27260156	NCIH2009	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	-0.2171650671160863	[782]	[1118,932,804]	-3	hSpCas9	negative selection	7904793
45989108	45989131	21	+	27260156	NCIH2009	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.489789507892469	[172]	[68,67,117]	-9	hSpCas9	negative selection	7904794
45990271	45990294	21	-	27260156	NCIH1373	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.33325069658669015	[2157]	[3485,2342,3313,834]	3	hSpCas9	negative selection	7961772
45989080	45989103	21	+	27260156	NCIH1373	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.8956304510905402	[271]	[585,369,930,100]	8	hSpCas9	negative selection	7961773
45987145	45987168	21	+	27260156	NCIH1373	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.5801096359471138	[0]	[0,0,0,0]	6	hSpCas9	negative selection	7961774
45990254	45990277	21	+	27260156	NCIH1373	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.8237926316070316	[204]	[34,8,25,16]	-9	hSpCas9	negative selection	8026043
45989108	45989131	21	-	27260156	NCIH1373	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.5372329250747218	[782]	[1462,1120,1337,316]	5	hSpCas9	negative selection	8026044
45989108	45989131	21	+	27260156	NCIH1373	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-4.228628035543476	[172]	[15,9,4,2]	-9	hSpCas9	negative selection	8026045
45990271	45990294	21	-	27260156	PATU8902	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.606321696786531	[2157]	[4729,5072,4295,4191]	6	hSpCas9	negative selection	8083023
45989080	45989103	21	+	27260156	PATU8902	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.6682015571416497	[271]	[300,698,689,706]	7	hSpCas9	negative selection	8083024
45987145	45987168	21	+	27260156	PATU8902	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.47507721586162077	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8083025
45990254	45990277	21	+	27260156	PATU8902	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-7.616225951723523	[204]	[0,1,0,1]	-9	hSpCas9	negative selection	8147294
45989108	45989131	21	-	27260156	PATU8902	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.41357782824954203	[782]	[1157,1510,1485,1663]	4	hSpCas9	negative selection	8147295
45989108	45989131	21	+	27260156	PATU8902	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-5.61706124742056	[172]	[2,7,5,1]	-9	hSpCas9	negative selection	8147296
45990271	45990294	21	-	27260156	PANC1	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3358534831682669	[2157]	[2173,2838,2564,1918]	5	hSpCas9	negative selection	8204274
45989080	45989103	21	+	27260156	PANC1	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.49070903068951915	[271]	[232,421,285,378]	7	hSpCas9	negative selection	8204275
45987145	45987168	21	+	27260156	PANC1	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.22557163962344795	[0]	[0,0,0,0]	3	hSpCas9	negative selection	8204276
45990254	45990277	21	+	27260156	PANC1	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.8376540141204762	[204]	[28,37,47,74]	-9	hSpCas9	negative selection	8268545
45989108	45989131	21	-	27260156	PANC1	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.07915188100257231	[782]	[580,923,824,570]	1	hSpCas9	negative selection	8268546
45989108	45989131	21	+	27260156	PANC1	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.3542657033594834	[172]	[64,35,94,34]	-9	hSpCas9	negative selection	8268547
45990271	45990294	21	-	27260156	PANC0813	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3902367237885218	[2157]	[3540,3012,3559,3197]	6	hSpCas9	negative selection	8325525
45989080	45989103	21	+	27260156	PANC0813	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.3006702677840402	[271]	[495,437,335,316]	5	hSpCas9	negative selection	8325526
45987145	45987168	21	+	27260156	PANC0813	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.23161252818376	[0]	[0,0,0,0]	-4	hSpCas9	negative selection	8325527
45990254	45990277	21	+	27260156	PANC0813	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.4544535906746487	[204]	[61,54,12,46]	-9	hSpCas9	negative selection	8389796
45989108	45989131	21	-	27260156	PANC0813	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.2707704153934284	[782]	[1236,1053,1301,869]	4	hSpCas9	negative selection	8389797
45989108	45989131	21	+	27260156	PANC0813	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.2520949605842544	[172]	[111,95,42,91]	-9	hSpCas9	negative selection	8389798
45990271	45990294	21	-	27260156	RDES	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.08249671292789573	[2157]	[2127,2481,2869,3164]	1	hSpCas9	negative selection	8446776
45989080	45989103	21	+	27260156	RDES	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.4679518538700791	[271]	[317,321,559,581]	7	hSpCas9	negative selection	8446777
45987145	45987168	21	+	27260156	RDES	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.18942035355372333	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	8446778
45990254	45990277	21	+	27260156	RDES	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.6722536140732809	[204]	[75,60,57,102]	-9	hSpCas9	negative selection	8511047
45989108	45989131	21	-	27260156	RDES	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.5008423213474625	[782]	[693,1718,1125,1658]	7	hSpCas9	negative selection	8511048
45989108	45989131	21	+	27260156	RDES	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.46191022731549	[172]	[41,89,31,135]	-9	hSpCas9	negative selection	8511049
45990271	45990294	21	-	27260156	PC3	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.2333828540155971	[2157]	[1839,2215,4121,2599]	5	hSpCas9	negative selection	8568027
45989080	45989103	21	+	27260156	PC3	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.10558019708237709	[271]	[219,331,473,202]	2	hSpCas9	negative selection	8568028
45987145	45987168	21	+	27260156	PC3	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.05753347684474441	[0]	[0,0,0,0]	1	hSpCas9	negative selection	8568029
45990254	45990277	21	+	27260156	PC3	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.26841908105375634	[204]	[140,115,280,178]	-6	hSpCas9	negative selection	8632298
45989108	45989131	21	-	27260156	PC3	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.31761156603167373	[782]	[703,1024,1432,910]	6	hSpCas9	negative selection	8632299
45989108	45989131	21	+	27260156	PC3	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.24086459548570782	[172]	[71,208,204,136]	-5	hSpCas9	negative selection	8632300
45990271	45990294	21	-	27260156	PATU8988T	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.2765245075054601	[2157]	[2716,2457,2263,2672]	5	hSpCas9	negative selection	8689278
45989080	45989103	21	+	27260156	PATU8988T	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.2830231932479922	[271]	[427,197,240,408]	5	hSpCas9	negative selection	8689279
45987145	45987168	21	+	27260156	PATU8988T	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.04952519822641044	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8689280
45990254	45990277	21	+	27260156	PATU8988T	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.20407207648861037	[204]	[236,170,55,229]	-3	hSpCas9	negative selection	8753549
45989108	45989131	21	-	27260156	PATU8988T	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.01562712494526808	[782]	[811,897,667,688]	0	hSpCas9	negative selection	8753550
45989108	45989131	21	+	27260156	PATU8988T	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.3185363937151644	[172]	[84,133,157,160]	-5	hSpCas9	negative selection	8753551
45990271	45990294	21	-	27260156	T47D	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.3413210549369441	[2157]	[3279,2873,3280,3334]	7	hSpCas9	negative selection	8810529
45989080	45989103	21	+	27260156	T47D	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.36979437174055685	[271]	[451,343,419,427]	7	hSpCas9	negative selection	8810530
45987145	45987168	21	+	27260156	T47D	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.2201891943612022	[0]	[0,0,0,0]	-5	hSpCas9	negative selection	8810531
45990254	45990277	21	+	27260156	T47D	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.1577053888058721	[204]	[83,147,81,110]	-9	hSpCas9	negative selection	8874800
45989108	45989131	21	-	27260156	T47D	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.19787692264076362	[782]	[999,1052,949,1186]	4	hSpCas9	negative selection	8874801
45989108	45989131	21	+	27260156	T47D	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.8475702854765275	[172]	[133,66,149,99]	-9	hSpCas9	negative selection	8874802
45990271	45990294	21	-	27260156	SU8686	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.4209406012811976	[2157]	[2709,2629,2881,3339]	7	hSpCas9	negative selection	8931780
45989080	45989103	21	+	27260156	SU8686	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.3901814216087425	[271]	[382,297,210,550]	6	hSpCas9	negative selection	8931781
45987145	45987168	21	+	27260156	SU8686	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.015103263740369854	[0]	[0,0,0,0]	0	hSpCas9	negative selection	8931782
45990254	45990277	21	+	27260156	SU8686	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-2.004581353912509	[204]	[73,44,21,59]	-9	hSpCas9	negative selection	8996051
45989108	45989131	21	-	27260156	SU8686	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.24475971025775667	[782]	[839,878,830,1175]	4	hSpCas9	negative selection	8996052
45989108	45989131	21	+	27260156	SU8686	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-1.1356217195085634	[172]	[70,80,70,90]	-8	hSpCas9	negative selection	8996053
45990271	45990294	21	-	27260156	SKES1	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.27500235089471836	[2157]	[3363,2646,2299,2238]	6	hSpCas9	negative selection	9053031
45989080	45989103	21	+	27260156	SKES1	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.37451559939953766	[271]	[471,398,260,300]	7	hSpCas9	negative selection	9053032
45987145	45987168	21	+	27260156	SKES1	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.007546427030755254	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9053033
45990254	45990277	21	+	27260156	SKES1	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-1.2842302125873324	[204]	[117,55,63,96]	-9	hSpCas9	negative selection	9117302
45989108	45989131	21	-	27260156	SKES1	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.14711321979473302	[782]	[1024,866,999,609]	3	hSpCas9	negative selection	9117303
45989108	45989131	21	+	27260156	SKES1	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.33437745802380503	[172]	[143,117,263,29]	-6	hSpCas9	negative selection	9117304
45990271	45990294	21	-	27260156	TOV112D	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.36990039390449647	[2157]	[3159,3567,2371,2302]	7	hSpCas9	negative selection	9174282
45989080	45989103	21	+	27260156	TOV112D	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.059753046621492056	[271]	[337,404,191,235]	1	hSpCas9	negative selection	9174283
45987145	45987168	21	+	27260156	TOV112D	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.0015868904355240687	[0]	[0,0,0,0]	0	hSpCas9	negative selection	9174284
45990254	45990277	21	+	27260156	TOV112D	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.32703551557762944	[204]	[82,99,177,267]	-6	hSpCas9	negative selection	9238553
45989108	45989131	21	-	27260156	TOV112D	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.45475463893330537	[782]	[1167,1399,984,838]	8	hSpCas9	negative selection	9238554
45989108	45989131	21	+	27260156	TOV112D	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.8261439890940308	[172]	[61,42,88,177]	-9	hSpCas9	negative selection	9238555
45990271	45990294	21	-	27260156	TC71	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.20147397315001037	[2157]	[2738,2438,2688,2776]	5	hSpCas9	negative selection	9295533
45989080	45989103	21	+	27260156	TC71	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.30832630423954127	[271]	[208,355,450,432]	7	hSpCas9	negative selection	9295534
45987145	45987168	21	+	27260156	TC71	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	-0.10019163119465624	[0]	[0,0,0,0]	-3	hSpCas9	negative selection	9295535
45990254	45990277	21	+	27260156	TC71	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.5153679072943937	[204]	[162,148,147,154]	-8	hSpCas9	negative selection	9359804
45989108	45989131	21	-	27260156	TC71	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.24604621490652012	[782]	[959,957,966,1104]	6	hSpCas9	negative selection	9359805
45989108	45989131	21	+	27260156	TC71	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.4777887917386663	[172]	[131,135,98,168]	-8	hSpCas9	negative selection	9359806
45990271	45990294	21	-	27260156	TC32	viability	CACGCTCACCTTGTAGCCCTTGG	COL6A1	ENSG00000142156	0.456817651059366	[2157]	[2569,2370,3213,3079]	7	hSpCas9	negative selection	9416784
45989080	45989103	21	+	27260156	TC32	viability	CCAGGGAGAACGAGGCAAGCCGG	COL6A1	ENSG00000142156	0.7243117288796304	[271]	[431,313,590,393]	9	hSpCas9	negative selection	9416785
45987145	45987168	21	+	27260156	TC32	viability	CTCTTTCCAGAAAAATAACGTGG	COL6A1	ENSG00000142156	0.11232540807230862	[0]	[0,0,0,0]	2	hSpCas9	negative selection	9416786
45990254	45990277	21	+	27260156	TC32	viability	GCAGGGCTCCAGGGGACCCAAGG	COL6A1	ENSG00000142156	-0.8216547637344227	[204]	[100,106,157,70]	-9	hSpCas9	negative selection	9481055
45989108	45989131	21	-	27260156	TC32	viability	CCGGCTTCTCCCTTCTCTCCTGG	COL6A1	ENSG00000142156	0.32929079364452296	[782]	[790,734,1344,933]	6	hSpCas9	negative selection	9481056
45989108	45989131	21	+	27260156	TC32	viability	CCAGGAGAGAAGGGAGAAGCCGG	COL6A1	ENSG00000142156	-0.5656546953792319	[172]	[128,100,118,83]	-8	hSpCas9	negative selection	9481057
45981891	45981914	21	-	27869803	HPAFII	viability after 27 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.373351081194155	[113]	[253,72,NaN]	9	hSpCas9	negative selection	9579615
45982742	45982765	21	+	27869803	HPAFII	viability after 27 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.08099400977253901	[315]	[214,142,NaN]	0	hSpCas9	negative selection	9579616
45984395	45984418	21	+	27869803	HPAFII	viability after 27 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.4470045874788764	[486]	[321,75,NaN]	-3	hSpCas9	negative selection	9579617
45986552	45986575	21	+	27869803	HPAFII	viability after 27 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.15248174338094864	[193]	[168,66,NaN]	1	hSpCas9	negative selection	9579618
45987642	45987665	21	-	27869803	HPAFII	viability after 27 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.3143826215644311	[586]	[377,139,NaN]	-2	hSpCas9	negative selection	9579619
45990246	45990269	21	+	27869803	HPAFII	viability after 27 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.7948855700953876	[26]	[11,4,NaN]	-5	hSpCas9	negative selection	9579620
45981891	45981914	21	-	27869803	HPAFII	viability after 15 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.0684130788024802	[113]	[481,116,NaN]	9	hSpCas9	negative selection	9662064
45982742	45982765	21	+	27869803	HPAFII	viability after 15 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.28648695733551954	[315]	[439,177,NaN]	-3	hSpCas9	negative selection	9662065
45984395	45984418	21	+	27869803	HPAFII	viability after 15 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.2526303748313159	[486]	[627,321,NaN]	-3	hSpCas9	negative selection	9662066
45986552	45986575	21	+	27869803	HPAFII	viability after 15 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.7122427143689614	[193]	[430,285,NaN]	7	hSpCas9	negative selection	9662067
45987642	45987665	21	-	27869803	HPAFII	viability after 15 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.11737685011114474	[586]	[1094,428,NaN]	1	hSpCas9	negative selection	9662068
45990246	45990269	21	+	27869803	HPAFII	viability after 15 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	0.7769684766178337	[26]	[111,10,NaN]	8	hSpCas9	negative selection	9662069
45981891	45981914	21	-	27869803	ASPC1	viability after 36 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	-0.856074430425301	[386]	[168,82,0]	-7	hSpCas9	negative selection	9744513
45982742	45982765	21	+	27869803	ASPC1	viability after 36 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	0.30367439793130413	[407]	[30,183,268]	3	hSpCas9	negative selection	9744514
45984395	45984418	21	+	27869803	ASPC1	viability after 36 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-1.769606999241756	[1073]	[43,201,81]	-9	hSpCas9	negative selection	9744515
45986552	45986575	21	+	27869803	ASPC1	viability after 36 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.5052634039489403	[513]	[143,212,43]	-5	hSpCas9	negative selection	9744516
45987642	45987665	21	-	27869803	ASPC1	viability after 36 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.4921387352176503	[1982]	[519,566,407]	-5	hSpCas9	negative selection	9744517
45990246	45990269	21	+	27869803	ASPC1	viability after 36 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-1.6655509874962848	[72]	[0,22,0]	-9	hSpCas9	negative selection	9744518
45981891	45981914	21	-	27869803	PATU8988S	viability after 35 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	-1.8395952167642293	[284]	[62,0,NaN]	-8	hSpCas9	negative selection	9826962
45982742	45982765	21	+	27869803	PATU8988S	viability after 35 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.06543312427251011	[490]	[180,196,NaN]	0	hSpCas9	negative selection	9826963
45984395	45984418	21	+	27869803	PATU8988S	viability after 35 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.38167128196102607	[644]	[314,361,NaN]	4	hSpCas9	negative selection	9826964
45986552	45986575	21	+	27869803	PATU8988S	viability after 35 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.037293072541597416	[422]	[172,158,NaN]	0	hSpCas9	negative selection	9826965
45987642	45987665	21	-	27869803	PATU8988S	viability after 35 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.21238815005206102	[1337]	[776,470,NaN]	2	hSpCas9	negative selection	9826966
45990246	45990269	21	+	27869803	PATU8988S	viability after 35 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-2.777064162267151	[33]	[0,2,NaN]	-9	hSpCas9	negative selection	9826967
45981891	45981914	21	-	27869803	PATU8988S	viability after 31 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	-1.5787886220675693	[284]	[52,18,NaN]	-8	hSpCas9	negative selection	9909411
45982742	45982765	21	+	27869803	PATU8988S	viability after 31 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.4509319529273653	[490]	[89,210,NaN]	-5	hSpCas9	negative selection	9909412
45984395	45984418	21	+	27869803	PATU8988S	viability after 31 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	0.1655522375271278	[644]	[203,395,NaN]	2	hSpCas9	negative selection	9909413
45986552	45986575	21	+	27869803	PATU8988S	viability after 31 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.45360324248162415	[422]	[153,328,NaN]	5	hSpCas9	negative selection	9909414
45987642	45987665	21	-	27869803	PATU8988S	viability after 31 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.4957025365351031	[1337]	[680,842,NaN]	6	hSpCas9	negative selection	9909415
45990246	45990269	21	+	27869803	PATU8988S	viability after 31 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.12435459006730021	[33]	[0,26,NaN]	-1	hSpCas9	negative selection	9909416
45981891	45981914	21	-	27869803	HPAFII	viability after 35 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.8080591532216264	[113]	[266,128,NaN]	9	hSpCas9	negative selection	9991860
45982742	45982765	21	+	27869803	HPAFII	viability after 35 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.2330558177214931	[315]	[121,151,NaN]	-1	hSpCas9	negative selection	9991861
45984395	45984418	21	+	27869803	HPAFII	viability after 35 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.49813242626943754	[486]	[230,110,NaN]	-3	hSpCas9	negative selection	9991862
45986552	45986575	21	+	27869803	HPAFII	viability after 35 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	-0.27987632355020253	[193]	[102,55,NaN]	-2	hSpCas9	negative selection	9991863
45987642	45987665	21	-	27869803	HPAFII	viability after 35 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	-0.3436672309468878	[586]	[236,230,NaN]	-2	hSpCas9	negative selection	9991864
45990246	45990269	21	+	27869803	HPAFII	viability after 35 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.3683136580187245	[26]	[11,8,NaN]	-2	hSpCas9	negative selection	9991865
45981891	45981914	21	-	27869803	HPAFII	viability after 31 days	ATCCTGCGCGGCTGTCCAGCAGG	COL6A1	ENSG00000142156	1.6642933971773037	[113]	[331,61,NaN]	9	hSpCas9	negative selection	10074309
45982742	45982765	21	+	27869803	HPAFII	viability after 31 days	TCATCGACAACCTGAGGGACAGG	COL6A1	ENSG00000142156	-0.03215234645647863	[315]	[171,174,NaN]	0	hSpCas9	negative selection	10074310
45984395	45984418	21	+	27869803	HPAFII	viability after 31 days	CGCGGTCAAGTACTTTGGGAAGG	COL6A1	ENSG00000142156	-0.419508329273788	[486]	[267,134,NaN]	-3	hSpCas9	negative selection	10074311
45986552	45986575	21	+	27869803	HPAFII	viability after 31 days	ACCTGATTGTGGTGACCGACGGG	COL6A1	ENSG00000142156	0.10909801911220879	[193]	[126,106,NaN]	0	hSpCas9	negative selection	10074312
45987642	45987665	21	-	27869803	HPAFII	viability after 31 days	CACCACTCACCTCAAAGCCGGGG	COL6A1	ENSG00000142156	0.1070747936740768	[586]	[439,261,NaN]	0	hSpCas9	negative selection	10074313
45990246	45990269	21	+	27869803	HPAFII	viability after 31 days	CTGTCTCCGCAGGGCTCCAGGGG	COL6A1	ENSG00000142156	-0.3739607129590241	[26]	[15,6,NaN]	-3	hSpCas9	negative selection	10074314
45986979	45987002	21	+	28162770	P31FUJ	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.2741577843055045	[56]	[80]	3	hSpCas9	negative selection	10136395
45989082	45989105	21	+	28162770	P31FUJ	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.01512530902920678	[175]	[208]	0	hSpCas9	negative selection	10136396
45990389	45990412	21	+	28162770	P31FUJ	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.5459600896740087	[81]	[65]	-4	hSpCas9	negative selection	10136397
45981838	45981861	21	+	28162770	P31FUJ	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.518474413927904	[166]	[136]	-4	hSpCas9	negative selection	10136398
45981909	45981932	21	+	28162770	P31FUJ	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.37126911925448236	[124]	[189]	4	hSpCas9	negative selection	10136399
45982623	45982646	21	+	28162770	P31FUJ	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.5182147334934135	[469]	[790]	6	hSpCas9	negative selection	10136400
45984311	45984334	21	+	28162770	P31FUJ	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.8579632595088037	[76]	[163]	8	hSpCas9	negative selection	10136401
45986584	45986607	21	+	28162770	P31FUJ	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.7098493659686471	[102]	[73]	-5	hSpCas9	negative selection	10136402
45986643	45986666	21	+	28162770	P31FUJ	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.393049291954337	[389]	[348]	-4	hSpCas9	negative selection	10136403
45986949	45986972	21	+	28162770	P31FUJ	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.11115219680298272	[77]	[98]	1	hSpCas9	negative selection	10136404
45986979	45987002	21	+	28162770	TF1	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10305761
45989082	45989105	21	+	28162770	TF1	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10305762
45990389	45990412	21	+	28162770	TF1	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10305763
45981838	45981861	21	+	28162770	TF1	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10305764
45981909	45981932	21	+	28162770	TF1	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10305765
45982623	45982646	21	+	28162770	TF1	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10305766
45984311	45984334	21	+	28162770	TF1	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10305767
45986584	45986607	21	+	28162770	TF1	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10305768
45986643	45986666	21	+	28162770	TF1	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10305769
45986949	45986972	21	+	28162770	TF1	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10305770
45986979	45987002	21	+	28162770	SKM1	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.277533975528909	[13]	[29]	2	hSpCas9	negative selection	10475127
45989082	45989105	21	+	28162770	SKM1	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.2253040167563512	[44]	[92]	2	hSpCas9	negative selection	10475128
45990389	45990412	21	+	28162770	SKM1	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.27451390271951226	[25]	[37]	-2	hSpCas9	negative selection	10475129
45981838	45981861	21	+	28162770	SKM1	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.4907957895466325	[61]	[77]	-4	hSpCas9	negative selection	10475130
45981909	45981932	21	+	28162770	SKM1	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10475131
45982623	45982646	21	+	28162770	SKM1	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.45702474057968967	[156]	[380]	4	hSpCas9	negative selection	10475132
45984311	45984334	21	+	28162770	SKM1	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-0.31950135749282227	[11]	[16]	-3	hSpCas9	negative selection	10475133
45986584	45986607	21	+	28162770	SKM1	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.2370391973008494	[19]	[14]	-7	hSpCas9	negative selection	10475134
45986643	45986666	21	+	28162770	SKM1	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.8038543513117462	[78]	[79]	-6	hSpCas9	negative selection	10475135
45986949	45986972	21	+	28162770	SKM1	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.6519294903104067	[17]	[49]	6	hSpCas9	negative selection	10475136
45986979	45987002	21	+	28162770	SKM1	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.277533975528909	[13]	[29]	2	hSpCas9	negative selection	10644493
45989082	45989105	21	+	28162770	SKM1	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.2253040167563512	[44]	[92]	2	hSpCas9	negative selection	10644494
45990389	45990412	21	+	28162770	SKM1	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.27451390271951226	[25]	[37]	-2	hSpCas9	negative selection	10644495
45981838	45981861	21	+	28162770	SKM1	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.4907957895466325	[61]	[77]	-4	hSpCas9	negative selection	10644496
45981909	45981932	21	+	28162770	SKM1	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10644497
45982623	45982646	21	+	28162770	SKM1	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.45702474057968967	[156]	[380]	4	hSpCas9	negative selection	10644498
45984311	45984334	21	+	28162770	SKM1	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-0.31950135749282227	[11]	[16]	-3	hSpCas9	negative selection	10644499
45986584	45986607	21	+	28162770	SKM1	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.2370391973008494	[19]	[14]	-7	hSpCas9	negative selection	10644500
45986643	45986666	21	+	28162770	SKM1	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.8038543513117462	[78]	[79]	-6	hSpCas9	negative selection	10644501
45986949	45986972	21	+	28162770	SKM1	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.6519294903104067	[17]	[49]	6	hSpCas9	negative selection	10644502
45986979	45987002	21	+	28162770	PL21	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-1.3578558386315667	[52]	[8]	-7	hSpCas9	negative selection	10813859
45989082	45989105	21	+	28162770	PL21	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.3272515323926594	[151]	[82]	3	hSpCas9	negative selection	10813860
45990389	45990412	21	+	28162770	PL21	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.5197524663179443	[55]	[16]	-4	hSpCas9	negative selection	10813861
45981838	45981861	21	+	28162770	PL21	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.12553088208385899	[192]	[76]	-1	hSpCas9	negative selection	10813862
45981909	45981932	21	+	28162770	PL21	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.2642699519090358	[87]	[45]	2	hSpCas9	negative selection	10813863
45982623	45982646	21	+	28162770	PL21	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.138999319675416	[481]	[230]	1	hSpCas9	negative selection	10813864
45984311	45984334	21	+	28162770	PL21	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-0.9518634789557301	[39]	[8]	-6	hSpCas9	negative selection	10813865
45986584	45986607	21	+	28162770	PL21	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.4628253982331092	[75]	[23]	-3	hSpCas9	negative selection	10813866
45986643	45986666	21	+	28162770	PL21	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	0.44019070232227464	[231]	[136]	4	hSpCas9	negative selection	10813867
45986949	45986972	21	+	28162770	PL21	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-0.13328411923587158	[62]	[24]	-1	hSpCas9	negative selection	10813868
45986979	45987002	21	+	28162770	P31FUJ	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.2741577843055045	[56]	[80]	3	hSpCas9	negative selection	10983225
45989082	45989105	21	+	28162770	P31FUJ	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.01512530902920678	[175]	[208]	0	hSpCas9	negative selection	10983226
45990389	45990412	21	+	28162770	P31FUJ	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.5459600896740087	[81]	[65]	-4	hSpCas9	negative selection	10983227
45981838	45981861	21	+	28162770	P31FUJ	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.518474413927904	[166]	[136]	-4	hSpCas9	negative selection	10983228
45981909	45981932	21	+	28162770	P31FUJ	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.37126911925448236	[124]	[189]	4	hSpCas9	negative selection	10983229
45982623	45982646	21	+	28162770	P31FUJ	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.5182147334934135	[469]	[790]	6	hSpCas9	negative selection	10983230
45984311	45984334	21	+	28162770	P31FUJ	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.8579632595088037	[76]	[163]	8	hSpCas9	negative selection	10983231
45986584	45986607	21	+	28162770	P31FUJ	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.7098493659686471	[102]	[73]	-5	hSpCas9	negative selection	10983232
45986643	45986666	21	+	28162770	P31FUJ	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.393049291954337	[389]	[348]	-4	hSpCas9	negative selection	10983233
45986949	45986972	21	+	28162770	P31FUJ	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.11115219680298272	[77]	[98]	1	hSpCas9	negative selection	10983234
45986979	45987002	21	+	28162770	OCIAML5	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.615027373563148	[27]	[32]	-4	hSpCas9	negative selection	11152591
45989082	45989105	21	+	28162770	OCIAML5	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	1.512296790343762	[66]	[344]	9	hSpCas9	negative selection	11152592
45990389	45990412	21	+	28162770	OCIAML5	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.5543860222233119	[47]	[58]	-4	hSpCas9	negative selection	11152593
45981838	45981861	21	+	28162770	OCIAML5	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.658124688303149	[138]	[158]	-4	hSpCas9	negative selection	11152594
45981909	45981932	21	+	28162770	OCIAML5	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-1.1785673955411835	[78]	[62]	-6	hSpCas9	negative selection	11152595
45982623	45982646	21	+	28162770	OCIAML5	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.2291911208596341	[232]	[492]	2	hSpCas9	negative selection	11152596
45984311	45984334	21	+	28162770	OCIAML5	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.5666465865582451	[48]	[130]	5	hSpCas9	negative selection	11152597
45986584	45986607	21	+	28162770	OCIAML5	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.6012584673634627	[78]	[46]	-7	hSpCas9	negative selection	11152598
45986643	45986666	21	+	28162770	OCIAML5	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.8104874671125974	[170]	[175]	-5	hSpCas9	negative selection	11152599
45986949	45986972	21	+	28162770	OCIAML5	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.3703258504724509	[38]	[90]	3	hSpCas9	negative selection	11152600
45986979	45987002	21	+	28162770	EOL1	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.7055026186791598	[129]	[41]	-5	hSpCas9	negative selection	11321957
45989082	45989105	21	+	28162770	EOL1	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.5164630329334575	[206]	[155]	5	hSpCas9	negative selection	11321958
45990389	45990412	21	+	28162770	EOL1	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-1.8550621600041652	[102]	[14]	-8	hSpCas9	negative selection	11321959
45981838	45981861	21	+	28162770	EOL1	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.2929291593517967	[292]	[125]	-2	hSpCas9	negative selection	11321960
45981909	45981932	21	+	28162770	EOL1	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.8457706581864173	[206]	[195]	7	hSpCas9	negative selection	11321961
45982623	45982646	21	+	28162770	EOL1	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.37399530163520955	[869]	[593]	3	hSpCas9	negative selection	11321962
45984311	45984334	21	+	28162770	EOL1	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-1.1723137676820543	[76]	[17]	-7	hSpCas9	negative selection	11321963
45986584	45986607	21	+	28162770	EOL1	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.23073045390737645	[97]	[43]	-2	hSpCas9	negative selection	11321964
45986643	45986666	21	+	28162770	EOL1	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.36495884562445036	[351]	[143]	-3	hSpCas9	negative selection	11321965
45986949	45986972	21	+	28162770	EOL1	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-0.5585351151314082	[122]	[43]	-4	hSpCas9	negative selection	11321966
45986979	45987002	21	+	28162770	MOLM13	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.8077450610688484	[91]	[37]	-4	hSpCas9	negative selection	11491323
45989082	45989105	21	+	28162770	MOLM13	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.9839568010546673	[192]	[275]	7	hSpCas9	negative selection	11491324
45990389	45990412	21	+	28162770	MOLM13	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.5976989600829978	[89]	[42]	-3	hSpCas9	negative selection	11491325
45981838	45981861	21	+	28162770	MOLM13	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.450810516353573	[275]	[145]	-3	hSpCas9	negative selection	11491326
45981909	45981932	21	+	28162770	MOLM13	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	1.419279437319957	[165]	[320]	9	hSpCas9	negative selection	11491327
45982623	45982646	21	+	28162770	MOLM13	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.8465634796045947	[682]	[887]	6	hSpCas9	negative selection	11491328
45984311	45984334	21	+	28162770	MOLM13	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.4278119421692437	[72]	[70]	3	hSpCas9	negative selection	11491329
45986584	45986607	21	+	28162770	MOLM13	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.1070194545126546	[142]	[95]	0	hSpCas9	negative selection	11491330
45986643	45986666	21	+	28162770	MOLM13	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.06062797218683402	[400]	[277]	0	hSpCas9	negative selection	11491331
45986949	45986972	21	+	28162770	MOLM13	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-2.090106071576308	[105]	[17]	-7	hSpCas9	negative selection	11491332
45986979	45987002	21	+	28162770	HEL	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-1.7030360048413733	[60]	[11]	-7	hSpCas9	negative selection	11660689
45989082	45989105	21	+	28162770	HEL	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	-0.8853613317651228	[198]	[68]	-5	hSpCas9	negative selection	11660690
45990389	45990412	21	+	28162770	HEL	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	-0.004380144783368678	[82]	[52]	0	hSpCas9	negative selection	11660691
45981838	45981861	21	+	28162770	HEL	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-1.2938991070022137	[244]	[63]	-6	hSpCas9	negative selection	11660692
45981909	45981932	21	+	28162770	HEL	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.8559828711226196	[112]	[130]	7	hSpCas9	negative selection	11660693
45982623	45982646	21	+	28162770	HEL	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	-0.480563949191385	[646]	[296]	-3	hSpCas9	negative selection	11660694
45984311	45984334	21	+	28162770	HEL	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	-0.7878955223295054	[61]	[22]	-5	hSpCas9	negative selection	11660695
45986584	45986607	21	+	28162770	HEL	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.4947646917495778	[109]	[24]	-7	hSpCas9	negative selection	11660696
45986643	45986666	21	+	28162770	HEL	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-1.032826217501706	[344]	[107]	-6	hSpCas9	negative selection	11660697
45986949	45986972	21	+	28162770	HEL	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-0.42597391808365703	[85]	[40]	-3	hSpCas9	negative selection	11660698
45986979	45987002	21	+	28162770	MV411	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.5469978326416831	[38]	[47]	5	hSpCas9	negative selection	11830055
45989082	45989105	21	+	28162770	MV411	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.4335338428962333	[137]	[156]	4	hSpCas9	negative selection	11830056
45990389	45990412	21	+	28162770	MV411	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.020027054679703005	[47]	[40]	0	hSpCas9	negative selection	11830057
45981838	45981861	21	+	28162770	MV411	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.7525624492172247	[175]	[87]	-5	hSpCas9	negative selection	11830058
45981909	45981932	21	+	28162770	MV411	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.43294451501706366	[124]	[77]	-3	hSpCas9	negative selection	11830059
45982623	45982646	21	+	28162770	MV411	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.47103472796450685	[512]	[598]	4	hSpCas9	negative selection	11830060
45984311	45984334	21	+	28162770	MV411	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.1319603333628392	[64]	[59]	1	hSpCas9	negative selection	11830061
45986584	45986607	21	+	28162770	MV411	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.11210483590436482	[67]	[52]	-1	hSpCas9	negative selection	11830062
45986643	45986666	21	+	28162770	MV411	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.30473501482071136	[260]	[177]	-2	hSpCas9	negative selection	11830063
45986949	45986972	21	+	28162770	MV411	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-1.0574170307456454	[83]	[33]	-6	hSpCas9	negative selection	11830064
45986979	45987002	21	+	28162770	MONOMAC1	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-0.7401791720860831	[50]	[34]	-6	hSpCas9	negative selection	11999421
45989082	45989105	21	+	28162770	MONOMAC1	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	0.9896638671335856	[75]	[172]	8	hSpCas9	negative selection	11999422
45990389	45990412	21	+	28162770	MONOMAC1	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	1.208955512616283	[39]	[105]	9	hSpCas9	negative selection	11999423
45981838	45981861	21	+	28162770	MONOMAC1	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.0704034085285366	[108]	[118]	0	hSpCas9	negative selection	11999424
45981909	45981932	21	+	28162770	MONOMAC1	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.0627357553479625	[81]	[89]	0	hSpCas9	negative selection	11999425
45982623	45982646	21	+	28162770	MONOMAC1	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.7248399284728106	[331]	[628]	7	hSpCas9	negative selection	11999426
45984311	45984334	21	+	28162770	MONOMAC1	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.4309943755534884	[21]	[33]	4	hSpCas9	negative selection	11999427
45986584	45986607	21	+	28162770	MONOMAC1	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	0.24466860268137036	[66]	[90]	2	hSpCas9	negative selection	11999428
45986643	45986666	21	+	28162770	MONOMAC1	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.23592586045314873	[187]	[182]	-2	hSpCas9	negative selection	11999429
45986949	45986972	21	+	28162770	MONOMAC1	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	2.794925833875028	[44]	[357]	9	hSpCas9	negative selection	11999430
45986979	45987002	21	+	28162770	OCIAML2	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	0.6317318923875166	[16]	[145]	6	hSpCas9	negative selection	12168787
45989082	45989105	21	+	28162770	OCIAML2	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	-0.8242667798568617	[45]	[143]	-5	hSpCas9	negative selection	12168788
45990389	45990412	21	+	28162770	OCIAML2	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.22326704703215894	[16]	[109]	2	hSpCas9	negative selection	12168789
45981838	45981861	21	+	28162770	OCIAML2	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	-0.2779847472997654	[34]	[159]	-2	hSpCas9	negative selection	12168790
45981909	45981932	21	+	28162770	OCIAML2	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	-0.10139601557644201	[35]	[185]	-1	hSpCas9	negative selection	12168791
45982623	45982646	21	+	28162770	OCIAML2	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.744083097946989	[73]	[686]	7	hSpCas9	negative selection	12168792
45984311	45984334	21	+	28162770	OCIAML2	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	1.114332675478995	[5]	[71]	9	hSpCas9	negative selection	12168793
45986584	45986607	21	+	28162770	OCIAML2	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-1.4706298252421612	[10]	[21]	-7	hSpCas9	negative selection	12168794
45986643	45986666	21	+	28162770	OCIAML2	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.4628103207828619	[45]	[184]	-4	hSpCas9	negative selection	12168795
45986949	45986972	21	+	28162770	OCIAML2	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	-0.06853138167081574	[13]	[73]	0	hSpCas9	negative selection	12168796
45986979	45987002	21	+	28162770	OCIAML3	viability	GTACCGGCGCAACTTCACGGCGG	COL6A1	ENSG00000142156	-1.206984517214916	[12]	[16]	-7	hSpCas9	negative selection	12338153
45989082	45989105	21	+	28162770	OCIAML3	viability	AGGGAGAACGAGGCAAGCCGGGG	COL6A1	ENSG00000142156	-0.2879045125984834	[54]	[135]	-2	hSpCas9	negative selection	12338154
45990389	45990412	21	+	28162770	OCIAML3	viability	CAAGCGTGGCATCGACGGGGTGG	COL6A1	ENSG00000142156	0.7026093660340116	[22]	[112]	6	hSpCas9	negative selection	12338155
45981838	45981861	21	+	28162770	OCIAML3	viability	GCAGGCCCCAGACATGAGGGCGG	COL6A1	ENSG00000142156	0.8458617119346162	[53]	[292]	7	hSpCas9	negative selection	12338156
45981909	45981932	21	+	28162770	OCIAML3	viability	AGGATGAGCCGGAGACCCCGAGG	COL6A1	ENSG00000142156	0.5592386199715189	[28]	[128]	5	hSpCas9	negative selection	12338157
45982623	45982646	21	+	28162770	OCIAML3	viability	TCTTCGGCCAGACTGCCCCGTGG	COL6A1	ENSG00000142156	0.1045498922389525	[117]	[382]	1	hSpCas9	negative selection	12338158
45984311	45984334	21	+	28162770	OCIAML3	viability	GCTGCACTACAGTGACGAGGTGG	COL6A1	ENSG00000142156	0.5214695770957727	[17]	[77]	5	hSpCas9	negative selection	12338159
45986584	45986607	21	+	28162770	OCIAML3	viability	GAGGGCTACAAGGAACCCTGTGG	COL6A1	ENSG00000142156	-0.8570420461579571	[20]	[34]	-6	hSpCas9	negative selection	12338160
45986643	45986666	21	+	28162770	OCIAML3	viability	GGGCGTCAAAGTCTTCTCGGTGG	COL6A1	ENSG00000142156	-0.35164680275511934	[81]	[193]	-3	hSpCas9	negative selection	12338161
45986949	45986972	21	+	28162770	OCIAML3	viability	GCGTCTGAGCATCATCGCCACGG	COL6A1	ENSG00000142156	0.3064566861249224	[29]	[111]	3	hSpCas9	negative selection	12338162