Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1337
• Symbol: COX6A1
• Description: cytochrome c oxidase subunit 6A1

DataSource: http://genomecrispr.dkfz.de/#!/results/COX6A1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
120438146	120438169	12	-	26472758	Jiyoye	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.11078237872564864	[139]	[113]	0	hSpCas9	negative selection	36024
120438146	120438169	12	-	26472758	KBM7	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.13824546790548814	[595,338]	[192,274]	1	hSpCas9	negative selection	227142
120438146	120438169	12	-	26472758	Raji	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.7930686245961123	[188]	[75]	7	hSpCas9	negative selection	418260
120438146	120438169	12	-	26472758	K562	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.0735341684628617	[375]	[333]	0	hSpCas9	negative selection	609378
120438146	120438169	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.11172007134983411	[2,3]	[3,1]	-1	hSpCas9	positive selection	2980747
120438112	120438135	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	-0.6154407584562498	[3,3]	[2,0]	-7	hSpCas9	positive selection	2980748
120438146	120438169	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.14344749287745273	[2,2]	[0,2]	2	hSpCas9	positive selection	3048605
120438112	120438135	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	0.019139837029472674	[3,3]	[3,1]	0	hSpCas9	positive selection	3048606
120438146	120438169	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	2.3501213374261205	[30,28]	[0,0]	8	hSpCas9	positive selection	3344274
120438146	120438169	12	-	26780180	HT29	viability (Avana library 4 designs)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	1.69934946796586	[]	[]	6	hSpCas9	negative selection	3417215
120438111	120438134	12	+	26780180	HT29	viability (Avana library 4 designs)	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	0.976556472720896	[]	[]	4	hSpCas9	negative selection	3417216
120438111	120438134	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	-7.5219711803149	[]	[]	-7	hSpCas9	negative selection	3495112
120438146	120438169	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	1.70574413652588	[]	[]	2	hSpCas9	negative selection	3495113
120438111	120438134	12	+	26780180	A375	viability (Avana lentiGuide)	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	2.95647222347938	[]	[]	3	hSpCas9	negative selection	3603771
120438146	120438169	12	-	26780180	A375	viability (Avana lentiGuide)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.940610929349135	[]	[]	1	hSpCas9	negative selection	3603772
120438111	120438134	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	-0.29122710941847946	[4]	[3,3]	-4	hSpCas9	positive selection	3712430
120438146	120438169	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.01179225956836677	[4]	[4,3]	0	hSpCas9	positive selection	3712431
120438111	120438134	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTCCAGATCAAAAATGGCGG	COX6A1	ENSG00000111775	-0.40291929859710324	[4]	[3,2]	-5	hSpCas9	positive selection	3821037
120438146	120438169	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.1868111937447303	[4]	[4,5]	4	hSpCas9	positive selection	3821038
120438146	120438169	12	-	26780180	A375	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.292843228218093	[]	[]	0	hSpCas9	negative selection	3929072
120438146	120438169	12	-	26780180	HT29	viability (GeCKOv2 library)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.884204440955317	[]	[]	4	hSpCas9	negative selection	4037038
120438146	120438169	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.3064518268090086	[1]	[0,0]	-6	hSpCas9	positive selection	4264538
120438129	120438152	12	+	27661255	K562	viability	GGCGGTAGTTGGTGTGTCCTCGG	COX6A1	ENSG00000111775	0.07286296984731377	[307,592]	[418,335]	2	dCas9-KRAB	negative selection	5472406
120438146	120438169	12	-	27260156	BXPC3	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.48513829627986693	[73]	[75,81,103,184]	8	hSpCas9	negative selection	5536998
120438146	120438169	12	-	27260156	A673	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.35470613636415393	[73]	[64,111,117,155]	7	hSpCas9	negative selection	5658249
120438146	120438169	12	-	27260156	A375	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.5250824732314503	[73]	[109,167,146,82]	7	hSpCas9	negative selection	5779500
120438146	120438169	12	-	27260156	COLO741	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.48220987117826786	[73]	[170,93,133]	8	hSpCas9	negative selection	5900751
120438146	120438169	12	-	27260156	CAL120	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.1413486035769722	[73]	[120,102,32]	-2	hSpCas9	negative selection	6022002
120438146	120438169	12	-	27260156	CADOES1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.4925503480418616	[73]	[39,40,31,83]	-7	hSpCas9	negative selection	6143253
120438146	120438169	12	-	27260156	EWS502	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.009075266251819869	[73]	[53,78,126,52]	0	hSpCas9	negative selection	6264504
120438146	120438169	12	-	27260156	EW8	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.23009924253427894	[73]	[96,62,82,38]	4	hSpCas9	negative selection	6385755
120438146	120438169	12	-	27260156	CORL105	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.42252682219531	[73]	[91,113,212,59]	7	hSpCas9	negative selection	6507006
120438146	120438169	12	-	27260156	HS294T	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.16914830274968784	[73]	[15,30,36,48]	2	hSpCas9	negative selection	6628257
120438146	120438169	12	-	27260156	HCC44	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.1592631911731779	[73]	[54,64,130,57]	-3	hSpCas9	negative selection	6749508
120438146	120438169	12	-	27260156	G402	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.1373036833753476	[73]	[63,89,27,140]	-2	hSpCas9	negative selection	6870759
120438146	120438169	12	-	27260156	L33	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.21083232980609923	[73]	[71,46,52,71]	4	hSpCas9	negative selection	6992010
120438146	120438169	12	-	27260156	K562	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.41516693286317485	[73]	[83,139,27,98]	5	hSpCas9	negative selection	7113261
120438146	120438169	12	-	27260156	HT29	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.5866862529227772	[73]	[56,83,66,35]	-7	hSpCas9	negative selection	7234512
120438146	120438169	12	-	27260156	MHHES1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.5724755841265416	[73]	[112,143,190,60]	8	hSpCas9	negative selection	7355763
120438146	120438169	12	-	27260156	MEWO	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.28432247537498734	[73]	[74,107,67]	6	hSpCas9	negative selection	7477014
120438146	120438169	12	-	27260156	LNCAPCLONEFGC	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.5847657639155992	[73]	[129,131,63,67]	8	hSpCas9	negative selection	7598265
120438146	120438169	12	-	27260156	PANC0327	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.11211551877160941	[73]	[27,145,74,21]	1	hSpCas9	negative selection	7719516
120438146	120438169	12	-	27260156	NCIH2009	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.2217711453832405	[73]	[105,209,40]	3	hSpCas9	negative selection	7840767
120438146	120438169	12	-	27260156	NCIH1373	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.08930160509063256	[73]	[234,34,73,8]	0	hSpCas9	negative selection	7962018
120438146	120438169	12	-	27260156	PATU8902	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.0714205643765049	[73]	[136,33,16,240]	0	hSpCas9	negative selection	8083269
120438146	120438169	12	-	27260156	PANC1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.021938000052976303	[73]	[27,146,37,61]	0	hSpCas9	negative selection	8204520
120438146	120438169	12	-	27260156	PANC0813	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.5477813687712692	[73]	[97,97,20,25]	-7	hSpCas9	negative selection	8325771
120438146	120438169	12	-	27260156	RDES	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.05064372335192413	[73]	[96,46,67,118]	-1	hSpCas9	negative selection	8447022
120438146	120438169	12	-	27260156	PC3	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.5325539023085684	[73]	[96,67,148,121]	9	hSpCas9	negative selection	8568273
120438146	120438169	12	-	27260156	PATU8988T	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	1.2137901909436553	[73]	[385,32,60,172]	9	hSpCas9	negative selection	8689524
120438146	120438169	12	-	27260156	T47D	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.050030040514867924	[73]	[61,71,106,117]	1	hSpCas9	negative selection	8810775
120438146	120438169	12	-	27260156	SU8686	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.6652786121168437	[73]	[62,147,90,172]	9	hSpCas9	negative selection	8932026
120438146	120438169	12	-	27260156	SKES1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.4442186618283448	[73]	[120,57,168,54]	8	hSpCas9	negative selection	9053277
120438146	120438169	12	-	27260156	TOV112D	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.3314940475149575	[73]	[29,77,42,85]	-6	hSpCas9	negative selection	9174528
120438146	120438169	12	-	27260156	TC71	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.25795656682118207	[73]	[66,112,81,119]	6	hSpCas9	negative selection	9295779
120438146	120438169	12	-	27260156	TC32	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.3351181335243325	[73]	[72,22,50,80]	-6	hSpCas9	negative selection	9417030
120438146	120438169	12	-	28162770	P31FUJ	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-1.0463890801834972	[231]	[131]	-6	hSpCas9	negative selection	10137132
120438146	120438169	12	-	28162770	TF1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10306498
120438146	120438169	12	-	28162770	SKM1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.49596838329667353	[72]	[181]	5	hSpCas9	negative selection	10475864
120438146	120438169	12	-	28162770	SKM1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.49596838329667353	[72]	[181]	5	hSpCas9	negative selection	10645230
120438146	120438169	12	-	28162770	PL21	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.1199692658053367	[221]	[104]	1	hSpCas9	negative selection	10814596
120438146	120438169	12	-	28162770	P31FUJ	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-1.0463890801834972	[231]	[131]	-6	hSpCas9	negative selection	10983962
120438146	120438169	12	-	28162770	OCIAML5	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.6237975831908799	[174]	[204]	-4	hSpCas9	negative selection	11153328
120438146	120438169	12	-	28162770	EOL1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.8769065490473853	[487]	[139]	-6	hSpCas9	negative selection	11322694
120438146	120438169	12	-	28162770	MOLM13	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	1.0008211795055195	[366]	[530]	7	hSpCas9	negative selection	11492060
120438146	120438169	12	-	28162770	HEL	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.9408201849333517	[304]	[374]	7	hSpCas9	negative selection	11661426
120438146	120438169	12	-	28162770	MV411	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.3807040816462396	[247]	[271]	3	hSpCas9	negative selection	11830792
120438146	120438169	12	-	28162770	MONOMAC1	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.3708039147962602	[140]	[124]	-3	hSpCas9	negative selection	12000158
120438146	120438169	12	-	28162770	OCIAML2	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	-0.07983987220999489	[44]	[235]	0	hSpCas9	negative selection	12169524
120438146	120438169	12	-	28162770	OCIAML3	viability	ACCCAGCAGCCGAGAAACCGAGG	COX6A1	ENSG00000111775	0.7983097824545973	[63]	[335]	7	hSpCas9	negative selection	12338890