Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1387
• Symbol: CREBBP
• Description: CREB binding lysine acetyltransferase

DataSource: http://genomecrispr.dkfz.de/#!/results/CREBBP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
3850949	3850972	16	-	26472758	Jiyoye	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	2.120461979202569	[42]	[140]	9	hSpCas9	negative selection	36854
3850718	3850741	16	-	26472758	Jiyoye	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.34590987802360984	[149]	[88]	-2	hSpCas9	negative selection	36855
3770859	3770882	16	+	26472758	Jiyoye	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.347712120657595	[242]	[17]	-9	hSpCas9	negative selection	36856
3769221	3769244	16	-	26472758	Jiyoye	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.035768114342855	[173]	[63]	-6	hSpCas9	negative selection	36857
3736080	3736103	16	-	26472758	Jiyoye	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.9141353702257564	[18]	[26]	6	hSpCas9	negative selection	36858
3780795	3780818	16	-	26472758	Jiyoye	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.0017360149761287413	[234]	[176]	0	hSpCas9	negative selection	36859
3740466	3740489	16	-	26472758	Jiyoye	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-2.3536369546147005	[121]	[17]	-8	hSpCas9	negative selection	36860
3740424	3740447	16	-	26472758	Jiyoye	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.062309901795346914	[125]	[90]	0	hSpCas9	negative selection	36861
3731263	3731286	16	-	26472758	Jiyoye	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	-0.617915599456957	[115]	[56]	-4	hSpCas9	negative selection	36862
3850865	3850888	16	-	26472758	Jiyoye	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	5.051031571280598	[0]	[24]	9	hSpCas9	negative selection	36863
3850949	3850972	16	-	26472758	KBM7	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-1.0718013465768657	[830,551]	[194,113]	-7	hSpCas9	negative selection	227972
3850718	3850741	16	-	26472758	KBM7	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-1.3809186359854064	[328,312]	[46,67]	-7	hSpCas9	negative selection	227973
3770859	3770882	16	+	26472758	KBM7	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.9077715727809375	[542,328]	[52,53]	-8	hSpCas9	negative selection	227974
3769221	3769244	16	-	26472758	KBM7	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.2512506844526594	[437,375]	[114,48]	-7	hSpCas9	negative selection	227975
3736080	3736103	16	-	26472758	KBM7	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-2.3291978145510224	[194,186]	[9,24]	-9	hSpCas9	negative selection	227976
3780795	3780818	16	-	26472758	KBM7	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-1.9600281775689166	[532,453]	[69,49]	-8	hSpCas9	negative selection	227977
3740466	3740489	16	-	26472758	KBM7	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.839092286094685	[222,120]	[42,44]	-6	hSpCas9	negative selection	227978
3740424	3740447	16	-	26472758	KBM7	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-5.956916416736836	[900,643]	[9,1]	-9	hSpCas9	negative selection	227979
3731263	3731286	16	-	26472758	KBM7	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.5905301678843711	[332,265]	[169,246]	6	hSpCas9	negative selection	227980
3850865	3850888	16	-	26472758	KBM7	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	0.6620440543100519	[42,14]	[8,30]	7	hSpCas9	negative selection	227981
3850949	3850972	16	-	26472758	Raji	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.6211053095118503	[338]	[120]	6	hSpCas9	negative selection	419090
3850718	3850741	16	-	26472758	Raji	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.16563495903281658	[260]	[53]	-1	hSpCas9	negative selection	419091
3770859	3770882	16	+	26472758	Raji	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-2.9715678060212225	[168]	[4]	-9	hSpCas9	negative selection	419092
3769221	3769244	16	-	26472758	Raji	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	0.7361277281226688	[118]	[45]	7	hSpCas9	negative selection	419093
3736080	3736103	16	-	26472758	Raji	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.24065006623706342	[123]	[33]	2	hSpCas9	negative selection	419094
3780795	3780818	16	-	26472758	Raji	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.16945666998522485	[188]	[38]	-1	hSpCas9	negative selection	419095
3740466	3740489	16	-	26472758	Raji	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	0.7100480378282146	[107]	[40]	6	hSpCas9	negative selection	419096
3740424	3740447	16	-	26472758	Raji	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	0.17826702153010932	[277]	[72]	1	hSpCas9	negative selection	419097
3731263	3731286	16	-	26472758	Raji	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	-0.06535099965553702	[256]	[56]	0	hSpCas9	negative selection	419098
3850865	3850888	16	-	26472758	Raji	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-2.0625414660687134	[17]	[0]	-8	hSpCas9	negative selection	419099
3850949	3850972	16	-	26472758	K562	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.8094981658105131	[626]	[301]	-5	hSpCas9	negative selection	610208
3850718	3850741	16	-	26472758	K562	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.0913298618077577	[235]	[186]	0	hSpCas9	negative selection	610209
3770859	3770882	16	+	26472758	K562	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.9030688846561103	[318]	[17]	-9	hSpCas9	negative selection	610210
3769221	3769244	16	-	26472758	K562	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-2.3405437730547094	[371]	[61]	-8	hSpCas9	negative selection	610211
3736080	3736103	16	-	26472758	K562	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-3.0604358538619745	[167]	[16]	-8	hSpCas9	negative selection	610212
3780795	3780818	16	-	26472758	K562	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-1.6515835517993356	[494]	[132]	-7	hSpCas9	negative selection	610213
3740466	3740489	16	-	26472758	K562	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.2260318919310036	[229]	[165]	-1	hSpCas9	negative selection	610214
3740424	3740447	16	-	26472758	K562	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.6458177061080108	[505]	[272]	-4	hSpCas9	negative selection	610215
3731263	3731286	16	-	26472758	K562	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	-0.13955671532153247	[290]	[222]	-1	hSpCas9	negative selection	610216
3850865	3850888	16	-	26472758	K562	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-5.003508785777138	[37]	[0]	-9	hSpCas9	negative selection	610217
3780861	3780884	16	-	26627737	DLD1	viability	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.2677020982927243	[752]	[148,351,342]	2	hSpCas9	negative selection	794072
3782802	3782825	16	+	26627737	DLD1	viability	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	1.373387672475241	[163]	[87,257,67]	9	hSpCas9	negative selection	794073
3793444	3793467	16	+	26627737	DLD1	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-1.3427188537295192	[714]	[138,63,63]	-8	hSpCas9	negative selection	794074
3810727	3810750	16	-	26627737	DLD1	viability	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.5678613031979561	[481]	[229,188,245]	6	hSpCas9	negative selection	794075
3850580	3850603	16	-	26627737	DLD1	viability	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.2916757832986707	[184]	[64,78,68]	3	hSpCas9	negative selection	794076
3879855	3879878	16	-	26627737	DLD1	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.5448333533377933	[280]	[234,36,110]	5	hSpCas9	negative selection	794077
3780861	3780884	16	-	26627737	GBM cells	viability after 5 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.14318230355306716	[373]	[216,225]	2	hSpCas9	negative selection	876387
3782802	3782825	16	+	26627737	GBM cells	viability after 5 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.18407548978534594	[160]	[79,71]	-3	hSpCas9	negative selection	876388
3793444	3793467	16	+	26627737	GBM cells	viability after 5 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.6931234208863675	[251]	[171,264]	8	hSpCas9	negative selection	876389
3810727	3810750	16	-	26627737	GBM cells	viability after 5 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.08532699911656672	[318]	[191,170]	1	hSpCas9	negative selection	876390
3850580	3850603	16	-	26627737	GBM cells	viability after 5 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.2901046322101616	[121]	[114,44]	4	hSpCas9	negative selection	876391
3879855	3879878	16	-	26627737	GBM cells	viability after 5 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.6191765902591222	[138]	[99,128]	8	hSpCas9	negative selection	876392
3780861	3780884	16	-	26627737	GBM cells	viability after 13 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	1.2774644128566568	[373]	[599,403]	9	hSpCas9	negative selection	958702
3782802	3782825	16	+	26627737	GBM cells	viability after 13 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.24539377335693136	[160]	[76,70]	-3	hSpCas9	negative selection	958703
3793444	3793467	16	+	26627737	GBM cells	viability after 13 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.220438974987423	[251]	[429,227]	9	hSpCas9	negative selection	958704
3810727	3810750	16	-	26627737	GBM cells	viability after 13 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.34792951706561226	[318]	[243,200]	4	hSpCas9	negative selection	958705
3850580	3850603	16	-	26627737	GBM cells	viability after 13 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.6594353303570246	[121]	[103,104]	7	hSpCas9	negative selection	958706
3879855	3879878	16	-	26627737	GBM cells	viability after 13 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.6278034048781216	[138]	[158,81]	7	hSpCas9	negative selection	958707
3780861	3780884	16	-	26627737	GBM cells	viability after 21 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	1.9510307680101997	[373]	[817,755]	9	hSpCas9	negative selection	1041017
3782802	3782825	16	+	26627737	GBM cells	viability after 21 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.3844545000721835	[160]	[109,117]	4	hSpCas9	negative selection	1041018
3793444	3793467	16	+	26627737	GBM cells	viability after 21 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.9069553066732383	[251]	[526,500]	9	hSpCas9	negative selection	1041019
3810727	3810750	16	-	26627737	GBM cells	viability after 21 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.22673452796676707	[318]	[230,176]	2	hSpCas9	negative selection	1041020
3850580	3850603	16	-	26627737	GBM cells	viability after 21 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.9553699829818195	[121]	[127,128]	8	hSpCas9	negative selection	1041021
3879855	3879878	16	-	26627737	GBM cells	viability after 21 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.3877313635894666	[138]	[206,188]	9	hSpCas9	negative selection	1041022
3780861	3780884	16	-	26627737	RPE1	viability after 9 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.32241940040133654	[1487]	[461,737]	2	hSpCas9	negative selection	1123332
3782802	3782825	16	+	26627737	RPE1	viability after 9 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.29399000083847227	[445]	[150,65]	-2	hSpCas9	negative selection	1123333
3793444	3793467	16	+	26627737	RPE1	viability after 9 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.3406243953944572	[711]	[189,157]	-2	hSpCas9	negative selection	1123334
3810727	3810750	16	-	26627737	RPE1	viability after 9 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.5095601868482613	[1294]	[567,588]	3	hSpCas9	negative selection	1123335
3850580	3850603	16	-	26627737	RPE1	viability after 9 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-1.3353478018410831	[700]	[41,144]	-7	hSpCas9	negative selection	1123336
3879855	3879878	16	-	26627737	RPE1	viability after 9 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.97154196469948	[199]	[307,164]	8	hSpCas9	negative selection	1123337
3780861	3780884	16	-	26627737	RPE1	viability after 12 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.08244161185092791	[1487]	[311,446]	0	hSpCas9	negative selection	1205647
3782802	3782825	16	+	26627737	RPE1	viability after 12 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.3023282144842915	[445]	[136,54]	-2	hSpCas9	negative selection	1205648
3793444	3793467	16	+	26627737	RPE1	viability after 12 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-1.4681137040762695	[711]	[56,81]	-7	hSpCas9	negative selection	1205649
3810727	3810750	16	-	26627737	RPE1	viability after 12 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.8206106897343306	[1294]	[664,560]	5	hSpCas9	negative selection	1205650
3850580	3850603	16	-	26627737	RPE1	viability after 12 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-1.2512929009155214	[700]	[82,74]	-7	hSpCas9	negative selection	1205651
3879855	3879878	16	-	26627737	RPE1	viability after 12 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.5492369596555449	[199]	[182,129]	8	hSpCas9	negative selection	1205652
3780861	3780884	16	-	26627737	RPE1	viability after 15 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.3614012043058994	[1487]	[262,389]	-2	hSpCas9	negative selection	1287962
3782802	3782825	16	+	26627737	RPE1	viability after 15 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-1.416804985995003	[445]	[32,60]	-7	hSpCas9	negative selection	1287963
3793444	3793467	16	+	26627737	RPE1	viability after 15 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.4199528707157066	[711]	[119,179]	-3	hSpCas9	negative selection	1287964
3810727	3810750	16	-	26627737	RPE1	viability after 15 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.6842549278975281	[1294]	[636,541]	4	hSpCas9	negative selection	1287965
3850580	3850603	16	-	26627737	RPE1	viability after 15 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-1.203436378368776	[700]	[79,91]	-6	hSpCas9	negative selection	1287966
3879855	3879878	16	-	26627737	RPE1	viability after 15 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.7302227361261424	[199]	[147,225]	8	hSpCas9	negative selection	1287967
3780861	3780884	16	-	26627737	RPE1	viability after 18 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.2699068707005108	[1487]	[348,315]	-2	hSpCas9	negative selection	1370277
3782802	3782825	16	+	26627737	RPE1	viability after 18 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.21302896464916243	[445]	[69,139]	-1	hSpCas9	negative selection	1370278
3793444	3793467	16	+	26627737	RPE1	viability after 18 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-1.4001798415632674	[711]	[66,78]	-7	hSpCas9	negative selection	1370279
3810727	3810750	16	-	26627737	RPE1	viability after 18 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	1.1083184462775255	[1294]	[591,925]	6	hSpCas9	negative selection	1370280
3850580	3850603	16	-	26627737	RPE1	viability after 18 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-1.193514140149961	[700]	[88,75]	-6	hSpCas9	negative selection	1370281
3879855	3879878	16	-	26627737	RPE1	viability after 18 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.9523203637699114	[199]	[248,165]	8	hSpCas9	negative selection	1370282
3780861	3780884	16	-	26627737	HeLa	viability after 8 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.08574026336390017	[839]	[416,387,250]	-1	hSpCas9	negative selection	1452592
3782802	3782825	16	+	26627737	HeLa	viability after 8 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	1.3237208006814982	[134]	[207,135,112]	8	hSpCas9	negative selection	1452593
3793444	3793467	16	+	26627737	HeLa	viability after 8 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.5587729553951545	[464]	[408,306,208]	5	hSpCas9	negative selection	1452594
3810727	3810750	16	-	26627737	HeLa	viability after 8 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	-0.015580099691373084	[575]	[331,132,293]	0	hSpCas9	negative selection	1452595
3850580	3850603	16	-	26627737	HeLa	viability after 8 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.41070238726758407	[382]	[617,2,136]	4	hSpCas9	negative selection	1452596
3879855	3879878	16	-	26627737	HeLa	viability after 8 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.08133585154980122	[431]	[258,64,279]	0	hSpCas9	negative selection	1452597
3780861	3780884	16	-	26627737	HeLa	viability after 12 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.035901180689977163	[839]	[260,439,354]	0	hSpCas9	negative selection	1534907
3782802	3782825	16	+	26627737	HeLa	viability after 12 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.9613437065987421	[134]	[39,135,144]	7	hSpCas9	negative selection	1534908
3793444	3793467	16	+	26627737	HeLa	viability after 12 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.6663271457498553	[464]	[442,294,181]	5	hSpCas9	negative selection	1534909
3810727	3810750	16	-	26627737	HeLa	viability after 12 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.43859027111660465	[575]	[515,241,223]	4	hSpCas9	negative selection	1534910
3850580	3850603	16	-	26627737	HeLa	viability after 12 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.3831247994037194	[382]	[133,87,145]	-3	hSpCas9	negative selection	1534911
3879855	3879878	16	-	26627737	HeLa	viability after 12 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.17248676586044503	[431]	[185,98,328]	1	hSpCas9	negative selection	1534912
3780861	3780884	16	-	26627737	HeLa	viability after 15 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.26177906330573797	[839]	[407,496,317]	2	hSpCas9	negative selection	1617222
3782802	3782825	16	+	26627737	HeLa	viability after 15 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	1.26687614493241	[134]	[102,78,221]	8	hSpCas9	negative selection	1617223
3793444	3793467	16	+	26627737	HeLa	viability after 15 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.9119017075392958	[464]	[391,199,485]	7	hSpCas9	negative selection	1617224
3810727	3810750	16	-	26627737	HeLa	viability after 15 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.1867505074097059	[575]	[410,130,255]	1	hSpCas9	negative selection	1617225
3850580	3850603	16	-	26627737	HeLa	viability after 15 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.5317935314426214	[382]	[137,42,144]	-5	hSpCas9	negative selection	1617226
3879855	3879878	16	-	26627737	HeLa	viability after 15 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.08112184954125912	[431]	[217,126,151]	0	hSpCas9	negative selection	1617227
3780861	3780884	16	-	26627737	HeLa	viability after 18 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.23737369267862207	[839]	[263,406,317]	2	hSpCas9	negative selection	1699537
3782802	3782825	16	+	26627737	HeLa	viability after 18 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	1.2094375954557843	[134]	[60,62,221]	8	hSpCas9	negative selection	1699538
3793444	3793467	16	+	26627737	HeLa	viability after 18 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.833813109158183	[464]	[230,159,485]	6	hSpCas9	negative selection	1699539
3810727	3810750	16	-	26627737	HeLa	viability after 18 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.23284545508825805	[575]	[288,112,255]	2	hSpCas9	negative selection	1699540
3850580	3850603	16	-	26627737	HeLa	viability after 18 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.48495647648983303	[382]	[99,34,144]	-4	hSpCas9	negative selection	1699541
3879855	3879878	16	-	26627737	HeLa	viability after 18 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.07488233663061547	[431]	[142,110,151]	0	hSpCas9	negative selection	1699542
3780861	3780884	16	-	26627737	HCT116	viability after 6 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-2.8227439501994493	[904]	[32,12]	-9	hSpCas9	negative selection	1781852
3782802	3782825	16	+	26627737	HCT116	viability after 6 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	1.6298128895427375	[407]	[552,2]	8	hSpCas9	negative selection	1781853
3793444	3793467	16	+	26627737	HCT116	viability after 6 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.18640464241208965	[829]	[346,38]	1	hSpCas9	negative selection	1781854
3810727	3810750	16	-	26627737	HCT116	viability after 6 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	2.2484760612489247	[334]	[208,272]	9	hSpCas9	negative selection	1781855
3850580	3850603	16	-	26627737	HCT116	viability after 6 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	4.045513596533908	[154]	[179,524]	9	hSpCas9	negative selection	1781856
3879855	3879878	16	-	26627737	HCT116	viability after 6 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.745229421554914	[655]	[168,174]	4	hSpCas9	negative selection	1781857
3780861	3780884	16	-	26627737	HCT116	viability after 8 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-1.8875663382483316	[845]	[148,154,74]	-9	hSpCas9	negative selection	1864167
3782802	3782825	16	+	26627737	HCT116	viability after 8 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.15192025620595045	[239]	[117,196,42]	-2	hSpCas9	negative selection	1864168
3793444	3793467	16	+	26627737	HCT116	viability after 8 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.17834107598980506	[335]	[233,188,205]	2	hSpCas9	negative selection	1864169
3810727	3810750	16	-	26627737	HCT116	viability after 8 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.26934343967974583	[296]	[188,238,163]	3	hSpCas9	negative selection	1864170
3850580	3850603	16	-	26627737	HCT116	viability after 8 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.002170786322521323	[154]	[39,126,87]	0	hSpCas9	negative selection	1864171
3879855	3879878	16	-	26627737	HCT116	viability after 8 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.44601823208704394	[139]	[97,99,116]	4	hSpCas9	negative selection	1864172
3780861	3780884	16	-	26627737	HCT116	viability after 9 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.7951339860679136	[904]	[193,95]	-5	hSpCas9	negative selection	1946482
3782802	3782825	16	+	26627737	HCT116	viability after 9 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.3533744393690851	[407]	[84,181]	2	hSpCas9	negative selection	1946483
3793444	3793467	16	+	26627737	HCT116	viability after 9 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.45740270681595685	[829]	[453,185]	3	hSpCas9	negative selection	1946484
3810727	3810750	16	-	26627737	HCT116	viability after 9 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	1.4450973956275899	[334]	[242,243]	8	hSpCas9	negative selection	1946485
3850580	3850603	16	-	26627737	HCT116	viability after 9 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	0.41117006480937035	[154]	[6,92]	3	hSpCas9	negative selection	1946486
3879855	3879878	16	-	26627737	HCT116	viability after 9 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.4768428435914221	[655]	[326,177]	3	hSpCas9	negative selection	1946487
3780861	3780884	16	-	26627737	HCT116	viability after 12 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-1.8521127312848265	[845]	[161,121,81]	-9	hSpCas9	negative selection	2028797
3782802	3782825	16	+	26627737	HCT116	viability after 12 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.2206709387927709	[239]	[103,200,140]	2	hSpCas9	negative selection	2028798
3793444	3793467	16	+	26627737	HCT116	viability after 12 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.3200481122984607	[335]	[98,179,149]	-3	hSpCas9	negative selection	2028799
3810727	3810750	16	-	26627737	HCT116	viability after 12 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.4262680928760817	[296]	[221,286,120]	4	hSpCas9	negative selection	2028800
3850580	3850603	16	-	26627737	HCT116	viability after 12 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.3802443677948135	[154]	[53,82,51]	-4	hSpCas9	negative selection	2028801
3879855	3879878	16	-	26627737	HCT116	viability after 12 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.3705245125463688	[139]	[185,186,197]	9	hSpCas9	negative selection	2028802
3780861	3780884	16	-	26627737	HCT116	viability after 15 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-2.3465865653963185	[845]	[150,102,39]	-9	hSpCas9	negative selection	2111112
3782802	3782825	16	+	26627737	HCT116	viability after 15 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.3273153454367853	[239]	[76,174,73]	-3	hSpCas9	negative selection	2111113
3793444	3793467	16	+	26627737	HCT116	viability after 15 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.08487768770965287	[335]	[86,336,175]	0	hSpCas9	negative selection	2111114
3810727	3810750	16	-	26627737	HCT116	viability after 15 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.6775331727634764	[296]	[286,248,283]	6	hSpCas9	negative selection	2111115
3850580	3850603	16	-	26627737	HCT116	viability after 15 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.7813695249079111	[154]	[21,98,30]	-7	hSpCas9	negative selection	2111116
3879855	3879878	16	-	26627737	HCT116	viability after 15 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.8077838876101836	[139]	[203,173,52]	7	hSpCas9	negative selection	2111117
3780861	3780884	16	-	26627737	HCT116	viability after 18 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-2.413632875931849	[845]	[76,61,92]	-9	hSpCas9	negative selection	2193427
3782802	3782825	16	+	26627737	HCT116	viability after 18 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.5813361123977783	[239]	[94,92,41]	-5	hSpCas9	negative selection	2193428
3793444	3793467	16	+	26627737	HCT116	viability after 18 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.1826437734526431	[335]	[36,206,182]	-2	hSpCas9	negative selection	2193429
3810727	3810750	16	-	26627737	HCT116	viability after 18 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.23660789773898355	[296]	[175,187,140]	2	hSpCas9	negative selection	2193430
3850580	3850603	16	-	26627737	HCT116	viability after 18 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-1.967705967280372	[154]	[10,17,28]	-9	hSpCas9	negative selection	2193431
3879855	3879878	16	-	26627737	HCT116	viability after 18 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.155513370212228	[139]	[289,44,122]	8	hSpCas9	negative selection	2193432
3850879	3850902	16	+	24336569	HL60	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	1.3694257817425983	[230]	[1262]	8	hSpCas9	negative selection	2258855
3850892	3850915	16	+	24336569	HL60	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	0.4116303797219193	[696]	[1961]	4	hSpCas9	negative selection	2258856
3850899	3850922	16	+	24336569	HL60	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	-0.26021736027860454	[501]	[886]	-2	hSpCas9	negative selection	2258857
3850936	3850959	16	+	24336569	HL60	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	0.13883442332853543	[393]	[917]	1	hSpCas9	negative selection	2258858
3850949	3850972	16	-	24336569	HL60	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-1.2022162600895065	[821]	[755]	-8	hSpCas9	negative selection	2258859
3879831	3879854	16	-	24336569	HL60	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	0.15879899754623927	[595]	[1407]	1	hSpCas9	negative selection	2258860
3879836	3879859	16	+	24336569	HL60	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	-0.21283066351524793	[562]	[1027]	-2	hSpCas9	negative selection	2258861
3879847	3879870	16	-	24336569	HL60	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	-0.0333698124278512	[117]	[243]	0	hSpCas9	negative selection	2258862
3879855	3879878	16	-	24336569	HL60	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.057764103590499605	[379]	[836]	0	hSpCas9	negative selection	2258863
3879894	3879917	16	-	24336569	HL60	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	-0.5613527442577082	[181]	[260]	-5	hSpCas9	negative selection	2258864
3850879	3850902	16	+	24336569	KBM7	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	0.7395063560516129	[194]	[887]	6	hSpCas9	negative selection	2326032
3850892	3850915	16	+	24336569	KBM7	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	-0.1687198235534063	[543]	[1319]	-1	hSpCas9	negative selection	2326033
3850899	3850922	16	+	24336569	KBM7	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	-3.586555609697693	[391]	[88]	-9	hSpCas9	negative selection	2326034
3850936	3850959	16	+	24336569	KBM7	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	0.0188436889968725	[261]	[723]	0	hSpCas9	negative selection	2326035
3850949	3850972	16	-	24336569	KBM7	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-3.4431740174288814	[326]	[81]	-9	hSpCas9	negative selection	2326036
3879831	3879854	16	-	24336569	KBM7	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	-2.9756393060355615	[521]	[180]	-9	hSpCas9	negative selection	2326037
3879836	3879859	16	+	24336569	KBM7	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	-0.05140072452135469	[461]	[1215]	0	hSpCas9	negative selection	2326038
3879847	3879870	16	-	24336569	KBM7	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	0.5524208034511178	[31]	[127]	5	hSpCas9	negative selection	2326039
3879855	3879878	16	-	24336569	KBM7	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.6486419679784876	[441]	[768]	-5	hSpCas9	negative selection	2326040
3879894	3879917	16	-	24336569	KBM7	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	-1.003972545073268	[99]	[135]	-6	hSpCas9	negative selection	2326041
3788834	3788857	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGGTACTCAGGAGGCTGAAG	CREBBP	ENSG00000005339	1.52400994621812	[40,24]	[4,37]	5	dCas9-VP64	positive selection	2398403
3863451	3863474	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGCTGAGCGTGGTGGTGG	CREBBP	ENSG00000005339	1.0062115233457334	[153,25]	[71,3]	4	dCas9-VP64	positive selection	2399671
3880200	3880223	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCGCGGTGGGGGCGCCCCGG	CREBBP	ENSG00000005339	1.7977316968951764	[11,9]	[13,0]	6	dCas9-VP64	positive selection	2435562
3880264	3880287	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGCCTGAGCCGCCCGGCCGGG	CREBBP	ENSG00000005339	6.930322029900694	[465,196]	[8332,9436]	9	dCas9-VP64	positive selection	2435563
3880287	3880310	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCGGCACCATGTTCTCGGGG	CREBBP	ENSG00000005339	-0.6385056377908106	[239,0]	[29,0]	-3	dCas9-VP64	positive selection	2435564
3788834	3788857	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGGTACTCAGGAGGCTGAAG	CREBBP	ENSG00000005339	0.38969770857698927	[82,65]	[43,19]	3	dCas9-VP64	positive selection	2493658
3863451	3863474	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGCTGAGCGTGGTGGTGG	CREBBP	ENSG00000005339	-0.08593954762364797	[86,223]	[25,66]	0	dCas9-VP64	positive selection	2494926
3880200	3880223	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCGCGGTGGGGGCGCCCCGG	CREBBP	ENSG00000005339	-0.37262886919830696	[65,80]	[24,10]	-4	dCas9-VP64	positive selection	2530817
3880264	3880287	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGCCTGAGCCGCCCGGCCGGG	CREBBP	ENSG00000005339	3.578548555527798	[322,237]	[510,1651]	9	dCas9-VP64	positive selection	2530818
3880287	3880310	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCGGCACCATGTTCTCGGGG	CREBBP	ENSG00000005339	0.32435352371583015	[17,6]	[6,2]	2	dCas9-VP64	positive selection	2530819
3879831	3879854	16	-	27260157	DLD1	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	0.393835198263875	[]	[]	4	hSpCas9	negative selection	2574591
3850841	3850864	16	-	27260157	DLD1	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.930668735265422	[]	[]	-6	hSpCas9	negative selection	2579148
3879836	3879859	16	+	27260157	DLD1	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	0.374255213461311	[]	[]	4	hSpCas9	negative selection	2580652
3879847	3879870	16	-	27260157	DLD1	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	-0.0188636673883939	[]	[]	0	hSpCas9	negative selection	2586161
3850892	3850915	16	+	27260157	DLD1	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	-0.469032709154687	[]	[]	-4	hSpCas9	negative selection	2604108
3850758	3850781	16	-	27260157	DLD1	viability	GCAGCCGAACAGTGCTAACATGG	CREBBP	ENSG00000005339	0.17029397259118	[]	[]	3	hSpCas9	negative selection	2607222
3850899	3850922	16	+	27260157	DLD1	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	0.782457895516872	[]	[]	8	hSpCas9	negative selection	2609470
3850770	3850793	16	+	27260157	DLD1	viability	TGTTCGGCTGCCCTTGAGCCTGG	CREBBP	ENSG00000005339	0.498960284770006	[]	[]	8	hSpCas9	negative selection	2612428
3850879	3850902	16	+	27260157	DLD1	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	-0.0767914463733687	[]	[]	0	hSpCas9	negative selection	2615911
3850372	3850395	16	+	27260157	DLD1	viability	CTCAGCCAGCACGCTGCTCGAGG	CREBBP	ENSG00000005339	1.2494310944496	[]	[]	9	hSpCas9	negative selection	2616499
3850629	3850652	16	+	27260157	DLD1	viability	GTGCTTGCGGATTCAGTGCTTGG	CREBBP	ENSG00000005339	1.11740505168329	[]	[]	9	hSpCas9	negative selection	2618211
3850331	3850354	16	-	27260157	DLD1	viability	CCGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-1.59033211862999	[]	[]	-8	hSpCas9	negative selection	2618240
3879894	3879917	16	-	27260157	DLD1	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	1.19648604571642	[]	[]	9	hSpCas9	negative selection	2619531
3850936	3850959	16	+	27260157	DLD1	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	-0.364723677489804	[]	[]	-3	hSpCas9	negative selection	2642738
3850723	3850746	16	+	27260157	DLD1	viability	GCTCAGAGGGCTCTTGCCCATGG	CREBBP	ENSG00000005339	0.92061507203431	[]	[]	9	hSpCas9	negative selection	2643765
3879855	3879878	16	-	27260157	DLD1	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.748062190548457	[]	[]	-5	hSpCas9	negative selection	2646367
3879851	3879874	16	+	27260157	DLD1	viability	GAAACCGGGCGAGCTGAGTTTGG	CREBBP	ENSG00000005339	-0.472172488376734	[]	[]	-4	hSpCas9	negative selection	2647843
3850514	3850537	16	-	27260157	DLD1	viability	GGCCTCCTCAATAGTAACTCTGG	CREBBP	ENSG00000005339	-1.03038820784502	[]	[]	-7	hSpCas9	negative selection	2648549
3879831	3879854	16	-	27260157	HT1080	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	2.69542160377003	[]	[]	9	hSpCas9	negative selection	2650721
3850841	3850864	16	-	27260157	HT1080	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	2.56239013203884	[]	[]	9	hSpCas9	negative selection	2655278
3879836	3879859	16	+	27260157	HT1080	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	2.7629585285113	[]	[]	9	hSpCas9	negative selection	2656782
3879847	3879870	16	-	27260157	HT1080	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	1.64849052102759	[]	[]	9	hSpCas9	negative selection	2662291
3850892	3850915	16	+	27260157	HT1080	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	1.2647172617175	[]	[]	8	hSpCas9	negative selection	2680238
3850758	3850781	16	-	27260157	HT1080	viability	GCAGCCGAACAGTGCTAACATGG	CREBBP	ENSG00000005339	2.67165371864449	[]	[]	9	hSpCas9	negative selection	2683352
3850899	3850922	16	+	27260157	HT1080	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	3.49758091751114	[]	[]	9	hSpCas9	negative selection	2685600
3850770	3850793	16	+	27260157	HT1080	viability	TGTTCGGCTGCCCTTGAGCCTGG	CREBBP	ENSG00000005339	1.44555931846553	[]	[]	9	hSpCas9	negative selection	2688558
3850879	3850902	16	+	27260157	HT1080	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	0.883225063644706	[]	[]	7	hSpCas9	negative selection	2692041
3850372	3850395	16	+	27260157	HT1080	viability	CTCAGCCAGCACGCTGCTCGAGG	CREBBP	ENSG00000005339	1.93825372136933	[]	[]	9	hSpCas9	negative selection	2692629
3850629	3850652	16	+	27260157	HT1080	viability	GTGCTTGCGGATTCAGTGCTTGG	CREBBP	ENSG00000005339	2.53085268426231	[]	[]	9	hSpCas9	negative selection	2694341
3850331	3850354	16	-	27260157	HT1080	viability	CCGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	1.49137957399409	[]	[]	9	hSpCas9	negative selection	2694370
3879894	3879917	16	-	27260157	HT1080	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	3.01013622457852	[]	[]	9	hSpCas9	negative selection	2695661
3850936	3850959	16	+	27260157	HT1080	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	1.30146043931544	[]	[]	9	hSpCas9	negative selection	2718868
3850723	3850746	16	+	27260157	HT1080	viability	GCTCAGAGGGCTCTTGCCCATGG	CREBBP	ENSG00000005339	2.16481159703011	[]	[]	9	hSpCas9	negative selection	2719895
3879855	3879878	16	-	27260157	HT1080	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	2.54576961666117	[]	[]	9	hSpCas9	negative selection	2722497
3879851	3879874	16	+	27260157	HT1080	viability	GAAACCGGGCGAGCTGAGTTTGG	CREBBP	ENSG00000005339	3.00703117021234	[]	[]	9	hSpCas9	negative selection	2723973
3850514	3850537	16	-	27260157	HT1080	viability	GGCCTCCTCAATAGTAACTCTGG	CREBBP	ENSG00000005339	1.0188856855384	[]	[]	8	hSpCas9	negative selection	2724679
3879831	3879854	16	-	27260157	MKN45	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	0.180261668522606	[]	[]	5	hSpCas9	negative selection	2726851
3850841	3850864	16	-	27260157	MKN45	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.507161184804301	[]	[]	-6	hSpCas9	negative selection	2731408
3879836	3879859	16	+	27260157	MKN45	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	0.529948392925873	[]	[]	6	hSpCas9	negative selection	2732912
3879847	3879870	16	-	27260157	MKN45	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	0.0520761449329526	[]	[]	0	hSpCas9	negative selection	2738421
3850892	3850915	16	+	27260157	MKN45	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	-0.175488488918832	[]	[]	0	hSpCas9	negative selection	2756368
3850758	3850781	16	-	27260157	MKN45	viability	GCAGCCGAACAGTGCTAACATGG	CREBBP	ENSG00000005339	0.717929638063459	[]	[]	7	hSpCas9	negative selection	2759482
3850899	3850922	16	+	27260157	MKN45	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	0.778192704996402	[]	[]	7	hSpCas9	negative selection	2761730
3850770	3850793	16	+	27260157	MKN45	viability	TGTTCGGCTGCCCTTGAGCCTGG	CREBBP	ENSG00000005339	0.457167669251779	[]	[]	6	hSpCas9	negative selection	2764688
3850879	3850902	16	+	27260157	MKN45	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	0.591644581269824	[]	[]	7	hSpCas9	negative selection	2768171
3850372	3850395	16	+	27260157	MKN45	viability	CTCAGCCAGCACGCTGCTCGAGG	CREBBP	ENSG00000005339	0.968377214432616	[]	[]	8	hSpCas9	negative selection	2768759
3850629	3850652	16	+	27260157	MKN45	viability	GTGCTTGCGGATTCAGTGCTTGG	CREBBP	ENSG00000005339	0.205926054918325	[]	[]	5	hSpCas9	negative selection	2770471
3850331	3850354	16	-	27260157	MKN45	viability	CCGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-1.13707949029265	[]	[]	-8	hSpCas9	negative selection	2770500
3879894	3879917	16	-	27260157	MKN45	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	1.71008644739866	[]	[]	9	hSpCas9	negative selection	2771791
3850936	3850959	16	+	27260157	MKN45	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	0.573093269613501	[]	[]	7	hSpCas9	negative selection	2794998
3850723	3850746	16	+	27260157	MKN45	viability	GCTCAGAGGGCTCTTGCCCATGG	CREBBP	ENSG00000005339	-1.01213909506595	[]	[]	-8	hSpCas9	negative selection	2796025
3879855	3879878	16	-	27260157	MKN45	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.78713086473838	[]	[]	9	hSpCas9	negative selection	2798627
3879851	3879874	16	+	27260157	MKN45	viability	GAAACCGGGCGAGCTGAGTTTGG	CREBBP	ENSG00000005339	0.696143307128595	[]	[]	7	hSpCas9	negative selection	2800103
3850514	3850537	16	-	27260157	MKN45	viability	GGCCTCCTCAATAGTAACTCTGG	CREBBP	ENSG00000005339	-1.33693142467253	[]	[]	-8	hSpCas9	negative selection	2800809
3879831	3879854	16	-	27260157	RKO	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	-2.97745109188738	[]	[]	-9	hSpCas9	negative selection	2802981
3850841	3850864	16	-	27260157	RKO	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-3.63441718373749	[]	[]	-9	hSpCas9	negative selection	2807538
3879836	3879859	16	+	27260157	RKO	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	-1.91022147225379	[]	[]	-9	hSpCas9	negative selection	2809042
3879847	3879870	16	-	27260157	RKO	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	-1.62793824925512	[]	[]	-9	hSpCas9	negative selection	2814551
3850892	3850915	16	+	27260157	RKO	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	-0.705015804556305	[]	[]	-7	hSpCas9	negative selection	2832498
3850758	3850781	16	-	27260157	RKO	viability	GCAGCCGAACAGTGCTAACATGG	CREBBP	ENSG00000005339	-0.293260807436371	[]	[]	-6	hSpCas9	negative selection	2835612
3850899	3850922	16	+	27260157	RKO	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	-1.49004495539475	[]	[]	-8	hSpCas9	negative selection	2837860
3850770	3850793	16	+	27260157	RKO	viability	TGTTCGGCTGCCCTTGAGCCTGG	CREBBP	ENSG00000005339	-0.238328000053422	[]	[]	-1	hSpCas9	negative selection	2840818
3850879	3850902	16	+	27260157	RKO	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	-0.414605255713218	[]	[]	-6	hSpCas9	negative selection	2844301
3850372	3850395	16	+	27260157	RKO	viability	CTCAGCCAGCACGCTGCTCGAGG	CREBBP	ENSG00000005339	-1.39953776939287	[]	[]	-8	hSpCas9	negative selection	2844889
3850629	3850652	16	+	27260157	RKO	viability	GTGCTTGCGGATTCAGTGCTTGG	CREBBP	ENSG00000005339	-0.744344121277135	[]	[]	-7	hSpCas9	negative selection	2846601
3850331	3850354	16	-	27260157	RKO	viability	CCGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-2.61815605009204	[]	[]	-9	hSpCas9	negative selection	2846630
3879894	3879917	16	-	27260157	RKO	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	-1.21759824991997	[]	[]	-8	hSpCas9	negative selection	2847921
3850936	3850959	16	+	27260157	RKO	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	-1.23871822166963	[]	[]	-8	hSpCas9	negative selection	2871128
3850723	3850746	16	+	27260157	RKO	viability	GCTCAGAGGGCTCTTGCCCATGG	CREBBP	ENSG00000005339	-1.43707335085814	[]	[]	-8	hSpCas9	negative selection	2872155
3879855	3879878	16	-	27260157	RKO	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.0451214465578099	[]	[]	0	hSpCas9	negative selection	2874757
3879851	3879874	16	+	27260157	RKO	viability	GAAACCGGGCGAGCTGAGTTTGG	CREBBP	ENSG00000005339	-1.06437498617472	[]	[]	-8	hSpCas9	negative selection	2876233
3850514	3850537	16	-	27260157	RKO	viability	GGCCTCCTCAATAGTAACTCTGG	CREBBP	ENSG00000005339	-2.88614821439038	[]	[]	-9	hSpCas9	negative selection	2876939
3879831	3879854	16	-	27260157	SF268	viability	TTCTCGGCGAATGACAGCACAGG	CREBBP	ENSG00000005339	0.569778178779542	[]	[]	8	hSpCas9	negative selection	2879111
3850841	3850864	16	-	27260157	SF268	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.32884844792052	[]	[]	4	hSpCas9	negative selection	2883668
3879836	3879859	16	+	27260157	SF268	viability	GCTGTCATTCGCCGAGAAACCGG	CREBBP	ENSG00000005339	0.260007390878767	[]	[]	4	hSpCas9	negative selection	2885172
3879847	3879870	16	-	27260157	SF268	viability	ACTCAGCTCGCCCGGTTTCTCGG	CREBBP	ENSG00000005339	0.615438926069918	[]	[]	8	hSpCas9	negative selection	2890681
3850892	3850915	16	+	27260157	SF268	viability	TTATGTTTGGAAGCAGCATCTGG	CREBBP	ENSG00000005339	0.20416804819547	[]	[]	3	hSpCas9	negative selection	2908628
3850758	3850781	16	-	27260157	SF268	viability	GCAGCCGAACAGTGCTAACATGG	CREBBP	ENSG00000005339	0.502789860304712	[]	[]	7	hSpCas9	negative selection	2911742
3850899	3850922	16	+	27260157	SF268	viability	TGGAAGCAGCATCTGGAACAAGG	CREBBP	ENSG00000005339	0.458491569603598	[]	[]	7	hSpCas9	negative selection	2913990
3850770	3850793	16	+	27260157	SF268	viability	TGTTCGGCTGCCCTTGAGCCTGG	CREBBP	ENSG00000005339	0.772726185008427	[]	[]	8	hSpCas9	negative selection	2916948
3850879	3850902	16	+	27260157	SF268	viability	CTCCGACAGTTGTTTATGTTTGG	CREBBP	ENSG00000005339	0.749761600942862	[]	[]	8	hSpCas9	negative selection	2920431
3850372	3850395	16	+	27260157	SF268	viability	CTCAGCCAGCACGCTGCTCGAGG	CREBBP	ENSG00000005339	0.762810575875369	[]	[]	8	hSpCas9	negative selection	2921019
3850629	3850652	16	+	27260157	SF268	viability	GTGCTTGCGGATTCAGTGCTTGG	CREBBP	ENSG00000005339	0.220467204674207	[]	[]	3	hSpCas9	negative selection	2922731
3850331	3850354	16	-	27260157	SF268	viability	CCGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-0.134268238083611	[]	[]	-1	hSpCas9	negative selection	2922760
3879894	3879917	16	-	27260157	SF268	viability	ATGGCTGAGAACTTGCTGGACGG	CREBBP	ENSG00000005339	0.856536409724974	[]	[]	9	hSpCas9	negative selection	2924051
3850936	3850959	16	+	27260157	SF268	viability	AAGGCCTAATTCTCCTCCATTGG	CREBBP	ENSG00000005339	0.815841770904372	[]	[]	8	hSpCas9	negative selection	2947258
3850723	3850746	16	+	27260157	SF268	viability	GCTCAGAGGGCTCTTGCCCATGG	CREBBP	ENSG00000005339	0.299735841598502	[]	[]	4	hSpCas9	negative selection	2948285
3879855	3879878	16	-	27260157	SF268	viability	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	1.09609783426352	[]	[]	9	hSpCas9	negative selection	2950887
3879851	3879874	16	+	27260157	SF268	viability	GAAACCGGGCGAGCTGAGTTTGG	CREBBP	ENSG00000005339	0.783328148891501	[]	[]	8	hSpCas9	negative selection	2952363
3850514	3850537	16	-	27260157	SF268	viability	GGCCTCCTCAATAGTAACTCTGG	CREBBP	ENSG00000005339	0.316952439791271	[]	[]	4	hSpCas9	negative selection	2953069
3778732	3778755	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	-0.08729277498724053	[3,3]	[5,0]	-1	hSpCas9	positive selection	2981076
3778699	3778722	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	0.11917968243029503	[4,4]	[4,3]	2	hSpCas9	positive selection	2981077
3778732	3778755	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	-0.5251038870419057	[3,3]	[2,0]	-7	hSpCas9	positive selection	3048934
3778699	3778722	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	0.20312737910604262	[4,4]	[2,3]	3	hSpCas9	positive selection	3048935
3850841	3850864		-	24336571	A375	resistance to PLX after 7 days	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.011389501123364	[7,8]	[16,16]	9	hSpCas9	positive selection	3107340
3850331	3850354		+	24336571	A375	resistance to PLX after 7 days	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	0.3405512545162881	[39,43]	[56,48]	8	hSpCas9	positive selection	3107341
3793404	3793427		-	24336571	A375	resistance to PLX after 7 days	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.7411935668826706	[30,35]	[51,59]	9	hSpCas9	positive selection	3107342
3793444	3793467		+	24336571	A375	resistance to PLX after 7 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.305717694200982	[8,9]	[11,10]	8	hSpCas9	positive selection	3107343
3850841	3850864		-	24336571	A375	resistance to PLX after 14 days	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.8242862312137631	[6,6]	[4,5]	7	hSpCas9	positive selection	3165133
3850331	3850354		+	24336571	A375	resistance to PLX after 14 days	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	0.8155532040450129	[34,38]	[25,34]	7	hSpCas9	positive selection	3165134
3793404	3793427		-	24336571	A375	resistance to PLX after 14 days	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	1.990512032729318	[26,28]	[45,56]	9	hSpCas9	positive selection	3165135
3793444	3793467		+	24336571	A375	resistance to PLX after 14 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.0495070101402997	[5,6]	[6,5]	8	hSpCas9	positive selection	3165136
3850841	3850864		-	24336571	A375	viability after 7 days	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.9431660153884256	[16]	[7,8]	-8	hSpCas9	negative selection	3222926
3850331	3850354		+	24336571	A375	viability after 7 days	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	0.4483781118912902	[31]	[39,43]	6	hSpCas9	negative selection	3222927
3793404	3793427		-	24336571	A375	viability after 7 days	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.19337006527932155	[30]	[30,35]	3	hSpCas9	negative selection	3222928
3793444	3793467		+	24336571	A375	viability after 7 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.14136929282189198	[10]	[8,9]	-2	hSpCas9	negative selection	3222929
3850841	3850864		-	24336571	A375	viability after 14 days	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-1.2003042633805807	[16]	[6,6]	-9	hSpCas9	negative selection	3280719
3850331	3850354		+	24336571	A375	viability after 14 days	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	0.29387865144202885	[31]	[34,38]	4	hSpCas9	negative selection	3280720
3793404	3793427		-	24336571	A375	viability after 14 days	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.06280588127553122	[30]	[26,28]	0	hSpCas9	negative selection	3280721
3793444	3793467		+	24336571	A375	viability after 14 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.5997101230638104	[10]	[5,6]	-6	hSpCas9	negative selection	3280722
3850841	3850864	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.84516459068299	[109,59]	[0,0]	4	hSpCas9	positive selection	3344507
3793404	3793427	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.9255387226921159	[304,275]	[0,0]	-6	hSpCas9	positive selection	3344508
3850332	3850355	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.04392809837418546	[133,162]	[0,0]	0	hSpCas9	positive selection	3344509
3793444	3793467	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.5568864933047428	[103,103]	[0,0]	3	hSpCas9	positive selection	3363733
3782791	3782814	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.631417037452424	[236,236]	[0,0]	-4	hSpCas9	positive selection	3363734
3782835	3782858	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.8254804244804372	[517,517]	[5,5]	4	hSpCas9	positive selection	3363735
3770859	3770882	16	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	2.48696465858085	[]	[]	8	hSpCas9	negative selection	3417550
3778732	3778755	16	-	26780180	HT29	viability (Avana library 4 designs)	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	-0.155003113934119	[]	[]	-2	hSpCas9	negative selection	3417551
3778699	3778722	16	-	26780180	HT29	viability (Avana library 4 designs)	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	-1.04273411077547	[]	[]	-9	hSpCas9	negative selection	3417552
3757998	3758021	16	-	26780180	HT29	viability (Avana library 4 designs)	TGGACCTCTCCACCATCAAGCGG	CREBBP	ENSG00000005339	1.57679361109285	[]	[]	6	hSpCas9	negative selection	3417553
3757998	3758021	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGACCTCTCCACCATCAAGCGG	CREBBP	ENSG00000005339	-5.23900489541996	[]	[]	-5	hSpCas9	negative selection	3495611
3770859	3770882	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-5.52482992822695	[]	[]	-6	hSpCas9	negative selection	3495612
3778699	3778722	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	-6.16039977250928	[]	[]	-6	hSpCas9	negative selection	3495613
3778732	3778755	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	-6.66159516685017	[]	[]	-6	hSpCas9	negative selection	3495614
3757998	3758021	16	-	26780180	A375	viability (Avana lentiGuide)	TGGACCTCTCCACCATCAAGCGG	CREBBP	ENSG00000005339	15.5021709869029	[]	[]	8	hSpCas9	negative selection	3604270
3770859	3770882	16	+	26780180	A375	viability (Avana lentiGuide)	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	23.9613242907493	[]	[]	9	hSpCas9	negative selection	3604271
3778699	3778722	16	-	26780180	A375	viability (Avana lentiGuide)	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	2.99342144347866	[]	[]	3	hSpCas9	negative selection	3604272
3778732	3778755	16	-	26780180	A375	viability (Avana lentiGuide)	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	4.14876088307272	[]	[]	4	hSpCas9	negative selection	3604273
3757998	3758021	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGACCTCTCCACCATCAAGCGG	CREBBP	ENSG00000005339	0.17913906297370694	[5]	[5,5]	5	hSpCas9	positive selection	3712929
3770859	3770882	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-0.26068095331315705	[3]	[3,2]	-4	hSpCas9	positive selection	3712930
3778699	3778722	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	0.3878665530492781	[5]	[7,7]	9	hSpCas9	positive selection	3712931
3778732	3778755	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	0.3841111451552427	[5]	[6,6]	9	hSpCas9	positive selection	3712932
3757998	3758021	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGACCTCTCCACCATCAAGCGG	CREBBP	ENSG00000005339	0.07588479680618856	[4]	[4,3]	1	hSpCas9	positive selection	3821536
3770859	3770882	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.953871883110317	[4]	[0,0]	-9	hSpCas9	positive selection	3821537
3778699	3778722	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGAGTCTGCCAACAGCAGGG	CREBBP	ENSG00000005339	0.6239042355190743	[5]	[7,7]	9	hSpCas9	positive selection	3821538
3778732	3778755	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTAGCCTATGCTAAGAAAGTGG	CREBBP	ENSG00000005339	0.5553693036405366	[5]	[6,6]	9	hSpCas9	positive selection	3821539
3850841	3850864	16	-	26780180	A375	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.49777754236447	[]	[]	8	hSpCas9	negative selection	3929557
3782835	3782858	16	+	26780180	A375	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.700066065111892	[]	[]	2	hSpCas9	negative selection	3929558
3782791	3782814	16	-	26780180	A375	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	1.07267427549934	[]	[]	5	hSpCas9	negative selection	3929559
3850332	3850355	16	-	26780180	A375	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.657460833165617	[]	[]	2	hSpCas9	negative selection	3929560
3793404	3793427	16	-	26780180	A375	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	1.74924023743029	[]	[]	9	hSpCas9	negative selection	3929561
3793444	3793467	16	+	26780180	A375	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.45509281663362	[]	[]	8	hSpCas9	negative selection	3929562
3850841	3850864	16	-	26780180	HT29	viability (GeCKOv2 library)	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	2.09453413499632	[]	[]	9	hSpCas9	negative selection	4037523
3782835	3782858	16	+	26780180	HT29	viability (GeCKOv2 library)	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.474324700776527	[]	[]	1	hSpCas9	negative selection	4037524
3782791	3782814	16	-	26780180	HT29	viability (GeCKOv2 library)	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	1.45832122303836	[]	[]	7	hSpCas9	negative selection	4037525
3850332	3850355	16	-	26780180	HT29	viability (GeCKOv2 library)	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	1.30589619345671	[]	[]	6	hSpCas9	negative selection	4037526
3793404	3793427	16	-	26780180	HT29	viability (GeCKOv2 library)	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.764612834784635	[]	[]	3	hSpCas9	negative selection	4037527
3793444	3793467	16	+	26780180	HT29	viability (GeCKOv2 library)	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.86541241029873	[]	[]	8	hSpCas9	negative selection	4037528
3850841	3850864	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.2790343811396035	[3]	[3,2]	7	hSpCas9	positive selection	4129596
3850331	3850354	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	0.2943018627419204	[5]	[4,4]	7	hSpCas9	positive selection	4129597
3793404	3793427	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.38776149939490107	[5]	[3,5]	8	hSpCas9	positive selection	4129598
3793444	3793467	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.15146882965530786	[3]	[1,2]	4	hSpCas9	positive selection	4129599
3850841	3850864	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.95043020722305	[4]	[1,3,3,3]	6	hSpCas9	positive selection	4193618
3850331	3850354	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGCGTGACCAGTCATTTGCGG	CREBBP	ENSG00000005339	1.4188474716732742	[5]	[6,5,5,6]	9	hSpCas9	positive selection	4193619
3793404	3793427	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	1.268519877295954	[5]	[5,5,5,6]	9	hSpCas9	positive selection	4193620
3793444	3793467	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	1.3951228217385245	[3]	[4,0,5,4]	9	hSpCas9	positive selection	4193621
3850841	3850864	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.297515978308989	[2]	[2,0]	-6	hSpCas9	positive selection	4264804
3793404	3793427	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.19215932303316507	[3]	[4,2]	4	hSpCas9	positive selection	4264805
3850332	3850355	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.6620620486191716	[3]	[4,3]	9	hSpCas9	positive selection	4264806
3793444	3793467	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.31903790328165504	[2]	[3,1]	6	hSpCas9	positive selection	4329074
3782791	3782814	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.5226313208347277	[3]	[3,3]	9	hSpCas9	positive selection	4329075
3782835	3782858	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.29352519473943905	[3]	[4,2]	6	hSpCas9	positive selection	4329076
3778094	3778116	16	-	27760321	OCIAML3	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.5403115644445142	[224,181]	[224,236]	6	hSpCas9	negative selection	4391650
3778762	3778784	16	-	27760321	OCIAML3	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	0.24170683888402125	[529,470]	[475,443]	3	hSpCas9	negative selection	4391651
3850331	3850353	16	-	27760321	OCIAML3	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-0.6714957760121887	[1024,895]	[513,413]	-6	hSpCas9	negative selection	4391652
3850841	3850863	16	-	27760321	OCIAML3	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-1.204813812635729	[503,474]	[114,232]	-8	hSpCas9	negative selection	4391653
3850868	3850890	16	-	27760321	OCIAML3	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	-1.7091001499035892	[624,569]	[131,156]	-8	hSpCas9	negative selection	4391654
3778094	3778116	16	-	27760321	OCIAML2	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	-0.6068475478697006	[224,181]	[94,123]	-6	hSpCas9	negative selection	4475113
3778762	3778784	16	-	27760321	OCIAML2	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	0.5266835025390196	[529,470]	[464,736]	7	hSpCas9	negative selection	4475114
3850331	3850353	16	-	27760321	OCIAML2	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-0.10147060591583101	[1024,895]	[631,841]	-1	hSpCas9	negative selection	4475115
3850841	3850863	16	-	27760321	OCIAML2	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.5664174853806798	[503,474]	[195,361]	-6	hSpCas9	negative selection	4475116
3850868	3850890	16	-	27760321	OCIAML2	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	-0.1963344223806332	[624,569]	[368,490]	-2	hSpCas9	negative selection	4475117
3778094	3778116	16	-	27760321	MV411	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.854770156790511	[224,181]	[181,330]	6	hSpCas9	negative selection	4558576
3778762	3778784	16	-	27760321	MV411	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	-0.594882133033583	[529,470]	[143,329]	-4	hSpCas9	negative selection	4558577
3850331	3850353	16	-	27760321	MV411	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	0.6390018638063835	[1024,895]	[551,1634]	5	hSpCas9	negative selection	4558578
3850841	3850863	16	-	27760321	MV411	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.3293513878812735	[503,474]	[148,419]	-2	hSpCas9	negative selection	4558579
3850868	3850890	16	-	27760321	MV411	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	1.4526255514675894	[624,569]	[1154,963]	9	hSpCas9	negative selection	4558580
3778094	3778116	16	-	27760321	HL60	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.8634354311522301	[224,181]	[277,324]	8	hSpCas9	negative selection	4642039
3778762	3778784	16	-	27760321	HL60	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	1.635493706289966	[529,470]	[1310,1222]	9	hSpCas9	negative selection	4642040
3850331	3850353	16	-	27760321	HL60	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	1.090843362966318	[1024,895]	[1782,1544]	9	hSpCas9	negative selection	4642041
3850841	3850863	16	-	27760321	HL60	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.70005355952849	[503,474]	[588,714]	7	hSpCas9	negative selection	4642042
3850868	3850890	16	-	27760321	HL60	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	2.0172900166547567	[624,569]	[1606,2364]	9	hSpCas9	negative selection	4642043
3778094	3778116	16	-	27760321	HT1080	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	3.5396730652876913	[181,141]	[707,796]	9	hSpCas9	negative selection	4725502
3778762	3778784	16	-	27760321	HT1080	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	5.309542074974938	[470,367]	[6721,6524]	9	hSpCas9	negative selection	4725503
3850331	3850353	16	-	27760321	HT1080	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	4.46682090385469	[895,698]	[7269,6756]	9	hSpCas9	negative selection	4725504
3850841	3850863	16	-	27760321	HT1080	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	4.528059964150165	[474,370]	[3835,3944]	9	hSpCas9	negative selection	4725505
3850868	3850890	16	-	27760321	HT1080	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	4.865305517520678	[569,444]	[6060,5708]	9	hSpCas9	negative selection	4725506
3778094	3778116	16	-	27760321	HT29	viability after 7 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	-0.14821193055037818	[181,141]	[214,150,200]	-2	hSpCas9	negative selection	4808965
3778762	3778784	16	-	27760321	HT29	viability after 7 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	0.7096904850342325	[470,367]	[894,964,789]	9	hSpCas9	negative selection	4808966
3850331	3850353	16	-	27760321	HT29	viability after 7 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	0.35613624835094093	[895,698]	[1495,1104,1358]	5	hSpCas9	negative selection	4808967
3850841	3850863	16	-	27760321	HT29	viability after 7 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.3508989260287644	[474,370]	[1023,503,601]	5	hSpCas9	negative selection	4808968
3850868	3850890	16	-	27760321	HT29	viability after 7 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	0.2666325366853123	[569,444]	[832,881,649]	4	hSpCas9	negative selection	4808969
3778094	3778116	16	-	27760321	HT29	viability after 25 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	1.2949151017031626	[181,141]	[482,450,422]	9	hSpCas9	negative selection	4892428
3778762	3778784	16	-	27760321	HT29	viability after 25 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	1.7068359691603214	[470,367]	[1206,1663,1876]	9	hSpCas9	negative selection	4892429
3850331	3850353	16	-	27760321	HT29	viability after 25 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	1.5359569947826623	[895,698]	[3009,2147,2754]	9	hSpCas9	negative selection	4892430
3850841	3850863	16	-	27760321	HT29	viability after 25 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.4754438054980266	[474,370]	[1313,1354,1365]	9	hSpCas9	negative selection	4892431
3850868	3850890	16	-	27760321	HT29	viability after 25 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	1.4083934938342806	[569,444]	[1452,1471,1714]	9	hSpCas9	negative selection	4892432
3778094	3778116	16	-	27760321	HT29	viability after 22 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	1.0085894891641083	[181,141]	[276,588,265]	9	hSpCas9	negative selection	4975891
3778762	3778784	16	-	27760321	HT29	viability after 22 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	1.6763819768378128	[470,367]	[1437,1505,1710]	9	hSpCas9	negative selection	4975892
3850331	3850353	16	-	27760321	HT29	viability after 22 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	1.4471067270241755	[895,698]	[2229,2569,2750]	9	hSpCas9	negative selection	4975893
3850841	3850863	16	-	27760321	HT29	viability after 22 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.1370241748188081	[474,370]	[1161,1002,1058]	9	hSpCas9	negative selection	4975894
3850868	3850890	16	-	27760321	HT29	viability after 22 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	1.186061576291021	[569,444]	[979,1317,1719]	9	hSpCas9	negative selection	4975895
3778094	3778116	16	-	27760321	HT29	viability after 19 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.28503229558356014	[181,141]	[184,427,65]	2	hSpCas9	negative selection	5059354
3778762	3778784	16	-	27760321	HT29	viability after 19 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	1.737508024933439	[470,367]	[1727,1988,1113]	9	hSpCas9	negative selection	5059355
3850331	3850353	16	-	27760321	HT29	viability after 19 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	1.0742755929615198	[895,698]	[2366,1548,1891]	9	hSpCas9	negative selection	5059356
3850841	3850863	16	-	27760321	HT29	viability after 19 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.1868830799611287	[474,370]	[958,1399,935]	9	hSpCas9	negative selection	5059357
3850868	3850890	16	-	27760321	HT29	viability after 19 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	0.9162272781837533	[569,444]	[1159,1113,1020]	8	hSpCas9	negative selection	5059358
3778094	3778116	16	-	27760321	HT29	viability after 16 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.41497634772740966	[181,141]	[380,90,269]	5	hSpCas9	negative selection	5142817
3778762	3778784	16	-	27760321	HT29	viability after 16 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	1.202804413800879	[470,367]	[1056,884,1301]	9	hSpCas9	negative selection	5142818
3850331	3850353	16	-	27760321	HT29	viability after 16 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	0.9745402620748871	[895,698]	[1520,1579,2140]	9	hSpCas9	negative selection	5142819
3850841	3850863	16	-	27760321	HT29	viability after 16 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.7302639538654829	[474,370]	[914,614,841]	8	hSpCas9	negative selection	5142820
3850868	3850890	16	-	27760321	HT29	viability after 16 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	1.1244309864092459	[569,444]	[852,1319,1501]	9	hSpCas9	negative selection	5142821
3778094	3778116	16	-	27760321	HT29	viability after 13 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.6733283646051192	[181,141]	[184,425,288]	8	hSpCas9	negative selection	5226280
3778762	3778784	16	-	27760321	HT29	viability after 13 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	0.6769847139314299	[470,367]	[774,810,749]	8	hSpCas9	negative selection	5226281
3850331	3850353	16	-	27760321	HT29	viability after 13 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	0.4253597655534487	[895,698]	[1168,1227,1324]	5	hSpCas9	negative selection	5226282
3850841	3850863	16	-	27760321	HT29	viability after 13 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.6397761312292611	[474,370]	[921,821,561]	8	hSpCas9	negative selection	5226283
3850868	3850890	16	-	27760321	HT29	viability after 13 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	0.887984199082251	[569,444]	[897,1452,927]	9	hSpCas9	negative selection	5226284
3778094	3778116	16	-	27760321	HT29	viability after 10 days	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.29532896672093123	[181,141]	[230,163,344]	4	hSpCas9	negative selection	5309743
3778762	3778784	16	-	27760321	HT29	viability after 10 days	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	0.4973150710991925	[470,367]	[834,955,439]	6	hSpCas9	negative selection	5309744
3850331	3850353	16	-	27760321	HT29	viability after 10 days	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	0.573777006733379	[895,698]	[1634,1016,1773]	7	hSpCas9	negative selection	5309745
3850841	3850863	16	-	27760321	HT29	viability after 10 days	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.15052333188481679	[474,370]	[553,687,520]	2	hSpCas9	negative selection	5309746
3850868	3850890	16	-	27760321	HT29	viability after 10 days	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	0.7194340891061946	[569,444]	[767,1189,1172]	8	hSpCas9	negative selection	5309747
3778094	3778116	16	-	27760321	MOLM13	viability	GGTCGCGTTTACATAAACAAGG	CREBBP	ENSG00000005339	0.2926035362967837	[224,181]	[302,0]	2	hSpCas9	negative selection	5393206
3778762	3778784	16	-	27760321	MOLM13	viability	GCTCTAAAGGATCGCCGCATGG	CREBBP	ENSG00000005339	-0.21834991950593607	[529,470]	[304,188]	-1	hSpCas9	negative selection	5393207
3850331	3850353	16	-	27760321	MOLM13	viability	CGCAAATGACTGGTCACGCGGG	CREBBP	ENSG00000005339	-0.3242431979639955	[1024,895]	[473,395]	-2	hSpCas9	negative selection	5393208
3850841	3850863	16	-	27760321	MOLM13	viability	GCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.027525457557183775	[503,474]	[439,146]	0	hSpCas9	negative selection	5393209
3850868	3850890	16	-	27760321	MOLM13	viability	AACTGTCGGAGCTTCTACGAGG	CREBBP	ENSG00000005339	1.5153311552498225	[624,569]	[1464,535]	9	hSpCas9	negative selection	5393210
3880622	3880645	16	+	27661255	K562	viability	GTTGTGGGGCCCGGGACCGGCGG	CREBBP	ENSG00000005339	-0.24020024259289324	[1110,1382]	[893,793]	-6	dCas9-KRAB	negative selection	5472679
3880181	3880204	16	-	27661255	K562	viability	GAGTGTCGCGCTCGGGAGGCGGG	CREBBP	ENSG00000005339	0.02118358386855959	[754,963]	[731,660]	0	dCas9-KRAB	negative selection	5472680
3880288	3880311	16	-	27661255	K562	viability	GGCGGCGGCACCATGTTCTCGGG	CREBBP	ENSG00000005339	-0.12428709516539871	[385,373]	[323,239]	-4	dCas9-KRAB	negative selection	5472681
3880647	3880670	16	-	27661255	K562	viability	GGCTTCGAGCGCGATCTACTCGG	CREBBP	ENSG00000005339	0.15155762831193256	[697,816]	[734,614]	5	dCas9-KRAB	negative selection	5472682
3850841	3850864	16	-	27260156	BXPC3	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	1.0720018467961974	[256]	[589,488,443,755]	9	hSpCas9	negative selection	5537264
3793404	3793427	16	-	27260156	BXPC3	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.9634022185444853	[846]	[1635,1637,1760,1896]	9	hSpCas9	negative selection	5537265
3850332	3850355	16	-	27260156	BXPC3	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	1.1733915305703255	[515]	[1046,1366,1242,1210]	9	hSpCas9	negative selection	5537266
3793444	3793467	16	+	27260156	BXPC3	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.7031506336596156	[296]	[536,417,415,667]	9	hSpCas9	negative selection	5601534
3782791	3782814	16	-	27260156	BXPC3	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.6530586692168328	[586]	[942,904,924,1102]	9	hSpCas9	negative selection	5601535
3782835	3782858	16	+	27260156	BXPC3	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	1.3787521343654676	[806]	[2090,2041,2262,2413]	9	hSpCas9	negative selection	5601536
3850841	3850864	16	-	27260156	A673	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.023666921749301628	[256]	[354,334,267,299]	0	hSpCas9	negative selection	5658515
3793404	3793427	16	-	27260156	A673	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.15586417610003078	[846]	[1299,1097,1094,1052]	4	hSpCas9	negative selection	5658516
3850332	3850355	16	-	27260156	A673	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.27039893141582705	[515]	[836,684,654,827]	6	hSpCas9	negative selection	5658517
3793444	3793467	16	+	27260156	A673	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.23814951192525424	[296]	[309,267,290,343]	-5	hSpCas9	negative selection	5722785
3782791	3782814	16	-	27260156	A673	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.07038526676172535	[586]	[772,624,657,638]	-2	hSpCas9	negative selection	5722786
3782835	3782858	16	+	27260156	A673	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.5525088878349537	[806]	[1715,1364,1203,1434]	9	hSpCas9	negative selection	5722787
3850841	3850864	16	-	27260156	A375	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.18065083799603532	[256]	[336,341,388,296]	2	hSpCas9	negative selection	5779766
3793404	3793427	16	-	27260156	A375	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.06604771210322202	[846]	[1111,1232,993,849]	0	hSpCas9	negative selection	5779767
3850332	3850355	16	-	27260156	A375	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.12082808376101353	[515]	[718,855,507,573]	1	hSpCas9	negative selection	5779768
3793444	3793467	16	+	27260156	A375	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.025752572302580212	[296]	[219,344,414,376]	0	hSpCas9	negative selection	5844036
3782791	3782814	16	-	27260156	A375	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.18752517073928385	[586]	[657,605,625,525]	-3	hSpCas9	negative selection	5844037
3782835	3782858	16	+	27260156	A375	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.46988325719024526	[806]	[1441,1223,1175,1357]	7	hSpCas9	negative selection	5844038
3850841	3850864	16	-	27260156	COLO741	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.003212719693653443	[256]	[319,394,274]	0	hSpCas9	negative selection	5901017
3793404	3793427	16	-	27260156	COLO741	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.029727853963035566	[846]	[1180,1100,1040]	0	hSpCas9	negative selection	5901018
3850332	3850355	16	-	27260156	COLO741	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.1719765830509953	[515]	[718,697,802]	3	hSpCas9	negative selection	5901019
3793444	3793467	16	+	27260156	COLO741	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.30997088027661734	[296]	[455,250,228]	-6	hSpCas9	negative selection	5965287
3782791	3782814	16	-	27260156	COLO741	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.17786060297655076	[586]	[764,539,688]	-4	hSpCas9	negative selection	5965288
3782835	3782858	16	+	27260156	COLO741	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.45517342011997497	[806]	[1303,1558,1368]	8	hSpCas9	negative selection	5965289
3850841	3850864	16	-	27260156	CAL120	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.24822233609074473	[256]	[388,384,366]	4	hSpCas9	negative selection	6022268
3793404	3793427	16	-	27260156	CAL120	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.391768427083093	[846]	[1734,1365,1104]	6	hSpCas9	negative selection	6022269
3850332	3850355	16	-	27260156	CAL120	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.36450487835076373	[515]	[840,879,761]	5	hSpCas9	negative selection	6022270
3793444	3793467	16	+	27260156	CAL120	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.34819330561977363	[296]	[829,259,376]	5	hSpCas9	negative selection	6086538
3782791	3782814	16	-	27260156	CAL120	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.027337812820373564	[586]	[1070,625,509]	0	hSpCas9	negative selection	6086539
3782835	3782858	16	+	27260156	CAL120	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.5627060062386305	[806]	[1639,1361,1470]	8	hSpCas9	negative selection	6086540
3850841	3850864	16	-	27260156	CADOES1	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.015420941432442659	[256]	[363,238,198,139]	0	hSpCas9	negative selection	6143519
3793404	3793427	16	-	27260156	CADOES1	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.176772701686714	[846]	[824,971,673,1098]	3	hSpCas9	negative selection	6143520
3850332	3850355	16	-	27260156	CADOES1	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.018197683860228034	[515]	[363,405,668,455]	0	hSpCas9	negative selection	6143521
3793444	3793467	16	+	27260156	CADOES1	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.3929578833030716	[296]	[231,300,164,140]	-6	hSpCas9	negative selection	6207789
3782791	3782814	16	-	27260156	CADOES1	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.08556479438746356	[586]	[539,532,567,679]	1	hSpCas9	negative selection	6207790
3782835	3782858	16	+	27260156	CADOES1	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.11789184252550278	[806]	[827,761,692,980]	2	hSpCas9	negative selection	6207791
3850841	3850864	16	-	27260156	EWS502	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.0998373246251768	[256]	[348,165,322,328]	1	hSpCas9	negative selection	6264770
3793404	3793427	16	-	27260156	EWS502	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.10676103452062224	[846]	[881,670,969,806]	-2	hSpCas9	negative selection	6264771
3850332	3850355	16	-	27260156	EWS502	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.021179273335165588	[515]	[526,583,559,546]	0	hSpCas9	negative selection	6264772
3793444	3793467	16	+	27260156	EWS502	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.24971830501937387	[296]	[199,237,213,424]	-4	hSpCas9	negative selection	6329040
3782791	3782814	16	-	27260156	EWS502	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.2737736055063522	[586]	[454,432,515,672]	-5	hSpCas9	negative selection	6329041
3782835	3782858	16	+	27260156	EWS502	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.0567240408324543	[806]	[751,971,950,891]	1	hSpCas9	negative selection	6329042
3850841	3850864	16	-	27260156	EW8	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.06517629279867898	[256]	[219,142,184,251]	-1	hSpCas9	negative selection	6386021
3793404	3793427	16	-	27260156	EW8	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.0346274345021248	[846]	[765,761,526,658]	0	hSpCas9	negative selection	6386022
3850332	3850355	16	-	27260156	EW8	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.08531095062489674	[515]	[545,328,382,335]	-2	hSpCas9	negative selection	6386023
3793444	3793467	16	+	27260156	EW8	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.49284053848352305	[296]	[274,138,165,115]	-7	hSpCas9	negative selection	6450291
3782791	3782814	16	-	27260156	EW8	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.2322728804901708	[586]	[397,394,337,497]	-4	hSpCas9	negative selection	6450292
3782835	3782858	16	+	27260156	EW8	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.30715985618437236	[806]	[886,829,660,889]	5	hSpCas9	negative selection	6450293
3850841	3850864	16	-	27260156	CORL105	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.4821665551448727	[256]	[213,145,255,252]	-7	hSpCas9	negative selection	6507272
3793404	3793427	16	-	27260156	CORL105	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.15587343698773604	[846]	[879,869,1041,791]	-3	hSpCas9	negative selection	6507273
3850332	3850355	16	-	27260156	CORL105	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.17901118900932123	[515]	[527,480,628,511]	-3	hSpCas9	negative selection	6507274
3793444	3793467	16	+	27260156	CORL105	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.501953114585739	[296]	[321,233,200,220]	-7	hSpCas9	negative selection	6571542
3782791	3782814	16	-	27260156	CORL105	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.22944815635867924	[586]	[689,486,567,601]	-4	hSpCas9	negative selection	6571543
3782835	3782858	16	+	27260156	CORL105	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.2671119791198572	[806]	[1386,1036,1240,909]	5	hSpCas9	negative selection	6571544
3850841	3850864	16	-	27260156	HS294T	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.9540626813174735	[256]	[264,63,308,115]	9	hSpCas9	negative selection	6628523
3793404	3793427	16	-	27260156	HS294T	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.7159254923338658	[846]	[557,525,517,547]	8	hSpCas9	negative selection	6628524
3850332	3850355	16	-	27260156	HS294T	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.8828867215909644	[515]	[332,507,324,289]	9	hSpCas9	negative selection	6628525
3793444	3793467	16	+	27260156	HS294T	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.22928998572399034	[296]	[68,220,118,131]	3	hSpCas9	negative selection	6692793
3782791	3782814	16	-	27260156	HS294T	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.4210743922232187	[586]	[282,315,358,248]	5	hSpCas9	negative selection	6692794
3782835	3782858	16	+	27260156	HS294T	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.4880215038934249	[806]	[290,390,354,785]	6	hSpCas9	negative selection	6692795
3850841	3850864	16	-	27260156	HCC44	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.8051391013335125	[256]	[568,242,944,392]	9	hSpCas9	negative selection	6749774
3793404	3793427	16	-	27260156	HCC44	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.46309122723710705	[846]	[1302,1076,1409,1522]	7	hSpCas9	negative selection	6749775
3850332	3850355	16	-	27260156	HCC44	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.4863854374763473	[515]	[988,760,694,820]	7	hSpCas9	negative selection	6749776
3793444	3793467	16	+	27260156	HCC44	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.46911971291967536	[296]	[313,502,369,627]	7	hSpCas9	negative selection	6814044
3782791	3782814	16	-	27260156	HCC44	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.02783205143151657	[586]	[860,525,905,395]	0	hSpCas9	negative selection	6814045
3782835	3782858	16	+	27260156	HCC44	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.9648609191277818	[806]	[2417,1514,1646,1609]	9	hSpCas9	negative selection	6814046
3850841	3850864	16	-	27260156	G402	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.3242346458862374	[256]	[414,240,114,252]	-4	hSpCas9	negative selection	6871025
3793404	3793427	16	-	27260156	G402	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.17881001214906223	[846]	[1005,603,1246,792]	-2	hSpCas9	negative selection	6871026
3850332	3850355	16	-	27260156	G402	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.29549606495376923	[515]	[555,672,459,382]	-4	hSpCas9	negative selection	6871027
3793444	3793467	16	+	27260156	G402	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.4302467417103276	[296]	[479,327,159,949]	5	hSpCas9	negative selection	6935295
3782791	3782814	16	-	27260156	G402	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.0683822995729978	[586]	[805,481,922,780]	0	hSpCas9	negative selection	6935296
3782835	3782858	16	+	27260156	G402	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	-0.13011493890984516	[806]	[908,972,814,903]	-2	hSpCas9	negative selection	6935297
3850841	3850864	16	-	27260156	L33	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.45775487930464115	[256]	[343,93,260,422]	8	hSpCas9	negative selection	6992276
3793404	3793427	16	-	27260156	L33	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.42663274640254545	[846]	[956,433,909,1095]	8	hSpCas9	negative selection	6992277
3850332	3850355	16	-	27260156	L33	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.0405179629831528	[515]	[538,208,303,588]	0	hSpCas9	negative selection	6992278
3793444	3793467	16	+	27260156	L33	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.14023744498009316	[296]	[282,122,201,404]	3	hSpCas9	negative selection	7056546
3782791	3782814	16	-	27260156	L33	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.05616327237284646	[586]	[575,196,350,641]	-1	hSpCas9	negative selection	7056547
3782835	3782858	16	+	27260156	L33	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.6300299188294812	[806]	[1133,450,911,1312]	9	hSpCas9	negative selection	7056548
3850841	3850864	16	-	27260156	K562	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.18065014454993233	[256]	[230,123,128,305]	-2	hSpCas9	negative selection	7113527
3793404	3793427	16	-	27260156	K562	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.09899652801070458	[846]	[1439,1021,464,400]	1	hSpCas9	negative selection	7113528
3850332	3850355	16	-	27260156	K562	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.17101720256688727	[515]	[451,338,573,662]	2	hSpCas9	negative selection	7113529
3793444	3793467	16	+	27260156	K562	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.016733437849773103	[296]	[288,221,306,248]	0	hSpCas9	negative selection	7177797
3782791	3782814	16	-	27260156	K562	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.16824234149644718	[586]	[428,815,552,544]	2	hSpCas9	negative selection	7177798
3782835	3782858	16	+	27260156	K562	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.11202017395463248	[806]	[858,778,1113,392]	1	hSpCas9	negative selection	7177799
3850841	3850864	16	-	27260156	HT29	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.05867284990255328	[256]	[426,276,346,259]	1	hSpCas9	negative selection	7234778
3793404	3793427	16	-	27260156	HT29	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.12250303350175928	[846]	[1095,1089,827,803]	-3	hSpCas9	negative selection	7234779
3850332	3850355	16	-	27260156	HT29	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.20201450367777765	[515]	[980,721,710,512]	4	hSpCas9	negative selection	7234780
3793444	3793467	16	+	27260156	HT29	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.40445129471969654	[296]	[311,224,322,232]	-6	hSpCas9	negative selection	7299048
3782791	3782814	16	-	27260156	HT29	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.017592330175008497	[586]	[1109,652,450,696]	0	hSpCas9	negative selection	7299049
3782835	3782858	16	+	27260156	HT29	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.48019762645058417	[806]	[1456,1321,1403,1292]	8	hSpCas9	negative selection	7299050
3850841	3850864	16	-	27260156	MHHES1	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.18909914721227705	[256]	[272,270,263,214]	-4	hSpCas9	negative selection	7356029
3793404	3793427	16	-	27260156	MHHES1	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.10013808257245527	[846]	[820,927,1205,640]	-2	hSpCas9	negative selection	7356030
3850332	3850355	16	-	27260156	MHHES1	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.26141602762363225	[515]	[841,877,710,436]	5	hSpCas9	negative selection	7356031
3793444	3793467	16	+	27260156	MHHES1	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.6483521903298022	[296]	[62,293,222,249]	-8	hSpCas9	negative selection	7420299
3782791	3782814	16	-	27260156	MHHES1	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.23193342694275185	[586]	[514,829,413,511]	-4	hSpCas9	negative selection	7420300
3782835	3782858	16	+	27260156	MHHES1	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.47788019961093176	[806]	[1306,1621,1088,1095]	8	hSpCas9	negative selection	7420301
3850841	3850864	16	-	27260156	MEWO	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.5148885243800517	[256]	[416,308,318]	9	hSpCas9	negative selection	7477280
3793404	3793427	16	-	27260156	MEWO	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.09972746481284211	[846]	[831,827,883]	2	hSpCas9	negative selection	7477281
3850332	3850355	16	-	27260156	MEWO	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.0891631980371747	[515]	[625,360,575]	2	hSpCas9	negative selection	7477282
3793444	3793467	16	+	27260156	MEWO	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.020724302066835953	[296]	[295,256,272]	0	hSpCas9	negative selection	7541550
3782791	3782814	16	-	27260156	MEWO	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.24213580223275524	[586]	[555,387,466]	-5	hSpCas9	negative selection	7541551
3782835	3782858	16	+	27260156	MEWO	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.4293548664360701	[806]	[1024,912,1113]	8	hSpCas9	negative selection	7541552
3850841	3850864	16	-	27260156	LNCAPCLONEFGC	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.4937790996648392	[256]	[250,279,504,305]	7	hSpCas9	negative selection	7598531
3793404	3793427	16	-	27260156	LNCAPCLONEFGC	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.15041298181331442	[846]	[803,854,922,834]	2	hSpCas9	negative selection	7598532
3850332	3850355	16	-	27260156	LNCAPCLONEFGC	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.20115789762999728	[515]	[464,497,610,589]	3	hSpCas9	negative selection	7598533
3793444	3793467	16	+	27260156	LNCAPCLONEFGC	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.3240370036779836	[296]	[254,213,222,167]	-5	hSpCas9	negative selection	7662801
3782791	3782814	16	-	27260156	LNCAPCLONEFGC	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.0037952016121290955	[586]	[665,553,470,427]	0	hSpCas9	negative selection	7662802
3782835	3782858	16	+	27260156	LNCAPCLONEFGC	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.41873900595531277	[806]	[1063,1057,935,836]	6	hSpCas9	negative selection	7662803
3850841	3850864	16	-	27260156	PANC0327	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.005681370472712333	[256]	[273,222,253,162]	0	hSpCas9	negative selection	7719782
3793404	3793427	16	-	27260156	PANC0327	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.4741007801885427	[846]	[608,524,462,576]	-6	hSpCas9	negative selection	7719783
3850332	3850355	16	-	27260156	PANC0327	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.18541832379868894	[515]	[498,273,525,337]	-3	hSpCas9	negative selection	7719784
3793444	3793467	16	+	27260156	PANC0327	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.5388360507472736	[296]	[146,200,183,188]	-6	hSpCas9	negative selection	7784052
3782791	3782814	16	-	27260156	PANC0327	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.1153847101074339	[586]	[762,593,195,717]	1	hSpCas9	negative selection	7784053
3782835	3782858	16	+	27260156	PANC0327	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.468240330524324	[806]	[1505,724,856,954]	7	hSpCas9	negative selection	7784054
3850841	3850864	16	-	27260156	NCIH2009	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.786444892369323	[256]	[938,570,410]	9	hSpCas9	negative selection	7841033
3793404	3793427	16	-	27260156	NCIH2009	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.06600291554581783	[846]	[1357,1063,1318]	0	hSpCas9	negative selection	7841034
3850332	3850355	16	-	27260156	NCIH2009	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.17675305355432827	[515]	[1179,840,493]	2	hSpCas9	negative selection	7841035
3793444	3793467	16	+	27260156	NCIH2009	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.06670364664138928	[296]	[480,324,399]	-1	hSpCas9	negative selection	7905303
3782791	3782814	16	-	27260156	NCIH2009	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.18836422096899247	[586]	[963,1032,808]	2	hSpCas9	negative selection	7905304
3782835	3782858	16	+	27260156	NCIH2009	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.34555525939504694	[806]	[1737,1315,1303]	5	hSpCas9	negative selection	7905305
3850841	3850864	16	-	27260156	NCIH1373	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.43917938610418294	[256]	[302,129,235,52]	-4	hSpCas9	negative selection	7962284
3793404	3793427	16	-	27260156	NCIH1373	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.17341218355486	[846]	[1146,642,577,284]	-2	hSpCas9	negative selection	7962285
3850332	3850355	16	-	27260156	NCIH1373	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.08591152066769542	[515]	[702,298,634,230]	0	hSpCas9	negative selection	7962286
3793444	3793467	16	+	27260156	NCIH1373	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.7811876493621581	[296]	[141,219,202,51]	-7	hSpCas9	negative selection	8026554
3782791	3782814	16	-	27260156	NCIH1373	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.23084024210666895	[586]	[729,607,419,131]	-2	hSpCas9	negative selection	8026555
3782835	3782858	16	+	27260156	NCIH1373	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.1129042000773346	[806]	[1372,856,984,197]	1	hSpCas9	negative selection	8026556
3850841	3850864	16	-	27260156	PATU8902	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.34461947857094966	[256]	[568,289,489,453]	3	hSpCas9	negative selection	8083535
3793404	3793427	16	-	27260156	PATU8902	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.8017150996021087	[846]	[2999,1449,1355,2639]	8	hSpCas9	negative selection	8083536
3850332	3850355	16	-	27260156	PATU8902	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.4614207549895952	[515]	[1255,1358,371,1138]	5	hSpCas9	negative selection	8083537
3793444	3793467	16	+	27260156	PATU8902	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.5246720336636824	[296]	[688,933,227,622]	5	hSpCas9	negative selection	8147805
3782791	3782814	16	-	27260156	PATU8902	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.18982972545838445	[586]	[725,648,1036,1332]	2	hSpCas9	negative selection	8147806
3782835	3782858	16	+	27260156	PATU8902	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	1.0898673183915344	[806]	[3909,1945,1696,2123]	9	hSpCas9	negative selection	8147807
3850841	3850864	16	-	27260156	PANC1	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.002082135031959864	[256]	[223,246,222,195]	0	hSpCas9	negative selection	8204786
3793404	3793427	16	-	27260156	PANC1	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.2855514699236845	[846]	[731,981,944,894]	4	hSpCas9	negative selection	8204787
3850332	3850355	16	-	27260156	PANC1	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.25372537501531756	[515]	[564,614,380,554]	4	hSpCas9	negative selection	8204788
3793444	3793467	16	+	27260156	PANC1	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.13794949922814959	[296]	[355,348,240,197]	2	hSpCas9	negative selection	8269056
3782791	3782814	16	-	27260156	PANC1	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.06812465297511738	[586]	[345,531,340,675]	-1	hSpCas9	negative selection	8269057
3782835	3782858	16	+	27260156	PANC1	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.8608797730898222	[806]	[1108,1550,1252,1177]	9	hSpCas9	negative selection	8269058
3850841	3850864	16	-	27260156	PANC0813	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.24625025971574865	[256]	[415,214,196,206]	-4	hSpCas9	negative selection	8326037
3793404	3793427	16	-	27260156	PANC0813	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.19277777340557045	[846]	[1045,832,761,855]	-3	hSpCas9	negative selection	8326038
3850332	3850355	16	-	27260156	PANC0813	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.14754941849771783	[515]	[686,651,865,491]	2	hSpCas9	negative selection	8326039
3793444	3793467	16	+	27260156	PANC0813	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.6407690323574979	[296]	[171,252,190,270]	-7	hSpCas9	negative selection	8390307
3782791	3782814	16	-	27260156	PANC0813	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.2478943908175203	[586]	[613,477,666,566]	-4	hSpCas9	negative selection	8390308
3782835	3782858	16	+	27260156	PANC0813	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.11399958588402226	[806]	[903,1038,1207,944]	1	hSpCas9	negative selection	8390309
3850841	3850864	16	-	27260156	RDES	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.29944695576833646	[256]	[287,356,348,484]	5	hSpCas9	negative selection	8447288
3793404	3793427	16	-	27260156	RDES	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.004020548515119238	[846]	[849,731,1164,1226]	0	hSpCas9	negative selection	8447289
3850332	3850355	16	-	27260156	RDES	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.020347566912202936	[515]	[513,402,758,785]	0	hSpCas9	negative selection	8447290
3793444	3793467	16	+	27260156	RDES	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.22675886796708689	[296]	[233,280,346,315]	-4	hSpCas9	negative selection	8511558
3782791	3782814	16	-	27260156	RDES	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.011002135334668983	[586]	[641,589,663,793]	0	hSpCas9	negative selection	8511559
3782835	3782858	16	+	27260156	RDES	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.28603229409591	[806]	[960,1273,1037,1254]	4	hSpCas9	negative selection	8511560
3850841	3850864	16	-	27260156	PC3	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.09848941314293158	[256]	[269,156,546,194]	2	hSpCas9	negative selection	8568539
3793404	3793427	16	-	27260156	PC3	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.07539965721106934	[846]	[608,756,1834,757]	1	hSpCas9	negative selection	8568540
3850332	3850355	16	-	27260156	PC3	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.09607761911128851	[515]	[342,506,938,603]	2	hSpCas9	negative selection	8568541
3793444	3793467	16	+	27260156	PC3	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.29742790648118744	[296]	[206,328,743,361]	6	hSpCas9	negative selection	8632809
3782791	3782814	16	-	27260156	PC3	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.1849542627617617	[586]	[425,523,1500,579]	4	hSpCas9	negative selection	8632810
3782835	3782858	16	+	27260156	PC3	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.38845473479091164	[806]	[704,1143,1882,830]	7	hSpCas9	negative selection	8632811
3850841	3850864	16	-	27260156	PATU8988T	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-2.4659335074390683	[256]	[40,46,26,66]	-9	hSpCas9	negative selection	8689790
3793404	3793427	16	-	27260156	PATU8988T	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.5528215030381016	[846]	[550,670,321,713]	-7	hSpCas9	negative selection	8689791
3850332	3850355	16	-	27260156	PATU8988T	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.7751835794523312	[515]	[309,192,205,461]	-8	hSpCas9	negative selection	8689792
3793444	3793467	16	+	27260156	PATU8988T	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-1.0397367971071578	[296]	[133,171,44,217]	-9	hSpCas9	negative selection	8754060
3782791	3782814	16	-	27260156	PATU8988T	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-1.0313806029816641	[586]	[425,198,207,269]	-9	hSpCas9	negative selection	8754061
3782835	3782858	16	+	27260156	PATU8988T	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	-0.1567899603664934	[806]	[537,760,775,729]	-3	hSpCas9	negative selection	8754062
3850841	3850864	16	-	27260156	T47D	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.029003101149017385	[256]	[294,294,333,297]	0	hSpCas9	negative selection	8811041
3793404	3793427	16	-	27260156	T47D	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.08909215080291566	[846]	[1133,889,1155,1029]	1	hSpCas9	negative selection	8811042
3850332	3850355	16	-	27260156	T47D	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	-0.09207667177769124	[515]	[503,560,578,612]	-2	hSpCas9	negative selection	8811043
3793444	3793467	16	+	27260156	T47D	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.37251471191845287	[296]	[289,211,309,260]	-7	hSpCas9	negative selection	8875311
3782791	3782814	16	-	27260156	T47D	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.151916215905364	[586]	[606,594,524,741]	-3	hSpCas9	negative selection	8875312
3782835	3782858	16	+	27260156	T47D	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.22802100634326117	[806]	[1158,1021,1063,1168]	5	hSpCas9	negative selection	8875313
3850841	3850864	16	-	27260156	SU8686	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.7249149710383235	[256]	[235,429,463,601]	9	hSpCas9	negative selection	8932292
3793404	3793427	16	-	27260156	SU8686	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.4944806612791619	[846]	[1031,896,1186,1754]	8	hSpCas9	negative selection	8932293
3850332	3850355	16	-	27260156	SU8686	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.4633671105838062	[515]	[687,591,763,806]	7	hSpCas9	negative selection	8932294
3793444	3793467	16	+	27260156	SU8686	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.05600921249336133	[296]	[353,200,225,363]	-1	hSpCas9	negative selection	8996562
3782791	3782814	16	-	27260156	SU8686	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.07127419667271617	[586]	[648,557,533,717]	1	hSpCas9	negative selection	8996563
3782835	3782858	16	+	27260156	SU8686	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.8738955409543868	[806]	[1225,1402,1362,1977]	9	hSpCas9	negative selection	8996564
3850841	3850864	16	-	27260156	SKES1	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	-0.07491406993675842	[256]	[165,259,254,276]	-2	hSpCas9	negative selection	9053543
3793404	3793427	16	-	27260156	SKES1	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.113998004876395	[846]	[890,1104,1002,693]	2	hSpCas9	negative selection	9053544
3850332	3850355	16	-	27260156	SKES1	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.20184607765371507	[515]	[613,751,414,603]	4	hSpCas9	negative selection	9053545
3793444	3793467	16	+	27260156	SKES1	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.1637297176472835	[296]	[271,398,210,198]	-4	hSpCas9	negative selection	9117813
3782791	3782814	16	-	27260156	SKES1	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.20612117217267392	[586]	[550,582,612,314]	-4	hSpCas9	negative selection	9117814
3782835	3782858	16	+	27260156	SKES1	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.41794810085737877	[806]	[1151,958,1122,1054]	8	hSpCas9	negative selection	9117815
3850841	3850864	16	-	27260156	TOV112D	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.38219055065369034	[256]	[358,303,243,425]	7	hSpCas9	negative selection	9174794
3793404	3793427	16	-	27260156	TOV112D	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	-0.1817556878827945	[846]	[703,1001,805,542]	-4	hSpCas9	negative selection	9174795
3850332	3850355	16	-	27260156	TOV112D	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.38277101299760263	[515]	[940,783,460,560]	7	hSpCas9	negative selection	9174796
3793444	3793467	16	+	27260156	TOV112D	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.29184114688504337	[296]	[228,109,332,264]	-5	hSpCas9	negative selection	9239064
3782791	3782814	16	-	27260156	TOV112D	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.2888529489751914	[586]	[368,754,591,271]	-5	hSpCas9	negative selection	9239065
3782835	3782858	16	+	27260156	TOV112D	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.17685048560486616	[806]	[729,1383,674,962]	3	hSpCas9	negative selection	9239066
3850841	3850864	16	-	27260156	TC71	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.15052204380957956	[256]	[334,270,233,389]	4	hSpCas9	negative selection	9296045
3793404	3793427	16	-	27260156	TC71	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.008266679704703073	[846]	[745,1138,849,923]	0	hSpCas9	negative selection	9296046
3850332	3850355	16	-	27260156	TC71	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.10588042746513732	[515]	[597,584,528,675]	2	hSpCas9	negative selection	9296047
3793444	3793467	16	+	27260156	TC71	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.19698360579972873	[296]	[298,277,217,319]	-5	hSpCas9	negative selection	9360315
3782791	3782814	16	-	27260156	TC71	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	-0.1935688859104093	[586]	[580,513,524,582]	-5	hSpCas9	negative selection	9360316
3782835	3782858	16	+	27260156	TC71	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.46016026028095014	[806]	[1035,1210,1194,1329]	9	hSpCas9	negative selection	9360317
3850841	3850864	16	-	27260156	TC32	viability	AGCGGCTCTAGTATCAACCCAGG	CREBBP	ENSG00000005339	0.7830560006775327	[256]	[418,310,478,481]	9	hSpCas9	negative selection	9417296
3793404	3793427	16	-	27260156	TC32	viability	GAATCACATGACGCATTGTCAGG	CREBBP	ENSG00000005339	0.19065695771915125	[846]	[933,710,1060,972]	3	hSpCas9	negative selection	9417297
3850332	3850355	16	-	27260156	TC32	viability	CCCGCAAATGACTGGTCACGCGG	CREBBP	ENSG00000005339	0.4073271074445205	[515]	[667,464,800,693]	7	hSpCas9	negative selection	9417298
3793444	3793467	16	+	27260156	TC32	viability	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	0.3968836237916525	[296]	[274,468,354,312]	7	hSpCas9	negative selection	9481566
3782791	3782814	16	-	27260156	TC32	viability	CAGCGAGCCTATGCTGCTCTCGG	CREBBP	ENSG00000005339	0.08058159719871821	[586]	[578,470,619,681]	1	hSpCas9	negative selection	9481567
3782835	3782858	16	+	27260156	TC32	viability	ATTTGGGTTACTTAAAGAAGTGG	CREBBP	ENSG00000005339	0.6627824903802028	[806]	[1086,909,1580,1351]	9	hSpCas9	negative selection	9481568
3780861	3780884	16	-	27869803	HPAFII	viability after 27 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.20134539236492655	[435]	[236,167,NaN]	-1	hSpCas9	negative selection	9557084
3782802	3782825	16	+	27869803	HPAFII	viability after 27 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.6108025056564158	[168]	[73,44,NaN]	-4	hSpCas9	negative selection	9557085
3793444	3793467	16	+	27869803	HPAFII	viability after 27 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.6150850254834077	[329]	[175,60,NaN]	-4	hSpCas9	negative selection	9557086
3810727	3810750	16	-	27869803	HPAFII	viability after 27 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.6790456182370249	[188]	[283,54,NaN]	5	hSpCas9	negative selection	9557087
3850580	3850603	16	-	27869803	HPAFII	viability after 27 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.27689562318848515	[96]	[82,7,NaN]	-2	hSpCas9	negative selection	9557088
3879855	3879878	16	-	27869803	HPAFII	viability after 27 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.14453875965402282	[219]	[150,65,NaN]	-1	hSpCas9	negative selection	9557089
3780861	3780884	16	-	27869803	HPAFII	viability after 15 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.027461160394896544	[435]	[780,259,NaN]	0	hSpCas9	negative selection	9639533
3782802	3782825	16	+	27869803	HPAFII	viability after 15 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-1.323012252813216	[168]	[42,90,NaN]	-8	hSpCas9	negative selection	9639534
3793444	3793467	16	+	27869803	HPAFII	viability after 15 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.42965340719613193	[329]	[414,168,NaN]	-5	hSpCas9	negative selection	9639535
3810727	3810750	16	-	27869803	HPAFII	viability after 15 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	1.2885858739525458	[188]	[933,223,NaN]	9	hSpCas9	negative selection	9639536
3850580	3850603	16	-	27869803	HPAFII	viability after 15 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.18443146263013088	[96]	[145,57,NaN]	-2	hSpCas9	negative selection	9639537
3879855	3879878	16	-	27869803	HPAFII	viability after 15 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.4175753340844073	[219]	[411,255,NaN]	5	hSpCas9	negative selection	9639538
3780861	3780884	16	-	27869803	ASPC1	viability after 36 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	3.032020053359951	[1017]	[4132,1817,2879]	9	hSpCas9	negative selection	9721982
3782802	3782825	16	+	27869803	ASPC1	viability after 36 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.9815061922027706	[379]	[177,266,313]	8	hSpCas9	negative selection	9721983
3793444	3793467	16	+	27869803	ASPC1	viability after 36 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.4005687340449639	[663]	[146,260,125]	-4	hSpCas9	negative selection	9721984
3810727	3810750	16	-	27869803	ASPC1	viability after 36 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.6952033926590396	[671]	[335,673,172]	6	hSpCas9	negative selection	9721985
3850580	3850603	16	-	27869803	ASPC1	viability after 36 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	2.015774974915856	[157]	[562,22,140]	9	hSpCas9	negative selection	9721986
3879855	3879878	16	-	27869803	ASPC1	viability after 36 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.629815813114361	[513]	[157,17,162]	-6	hSpCas9	negative selection	9721987
3780861	3780884	16	-	27869803	PATU8988S	viability after 35 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-1.474494062570591	[921]	[189,76,NaN]	-8	hSpCas9	negative selection	9804431
3782802	3782825	16	+	27869803	PATU8988S	viability after 35 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-0.08781759174809167	[346]	[131,130,NaN]	-1	hSpCas9	negative selection	9804432
3793444	3793467	16	+	27869803	PATU8988S	viability after 35 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-2.4787365531691927	[630]	[85,4,NaN]	-9	hSpCas9	negative selection	9804433
3810727	3810750	16	-	27869803	PATU8988S	viability after 35 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.3113652836297123	[523]	[207,315,NaN]	3	hSpCas9	negative selection	9804434
3850580	3850603	16	-	27869803	PATU8988S	viability after 35 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.06962417604890114	[175]	[86,47,NaN]	0	hSpCas9	negative selection	9804435
3879855	3879878	16	-	27869803	PATU8988S	viability after 35 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.49410766445583476	[389]	[120,101,NaN]	-5	hSpCas9	negative selection	9804436
3780861	3780884	16	-	27869803	PATU8988S	viability after 31 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-1.7860491575422204	[921]	[121,86,NaN]	-9	hSpCas9	negative selection	9886880
3782802	3782825	16	+	27869803	PATU8988S	viability after 31 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	0.10030819899065058	[346]	[179,107,NaN]	1	hSpCas9	negative selection	9886881
3793444	3793467	16	+	27869803	PATU8988S	viability after 31 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-2.5473194625309197	[630]	[57,23,NaN]	-9	hSpCas9	negative selection	9886882
3810727	3810750	16	-	27869803	PATU8988S	viability after 31 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.4168723342034764	[523]	[197,381,NaN]	5	hSpCas9	negative selection	9886883
3850580	3850603	16	-	27869803	PATU8988S	viability after 31 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.19949455962305684	[175]	[39,87,NaN]	-2	hSpCas9	negative selection	9886884
3879855	3879878	16	-	27869803	PATU8988S	viability after 31 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.5849286300907284	[389]	[82,129,NaN]	-6	hSpCas9	negative selection	9886885
3780861	3780884	16	-	27869803	HPAFII	viability after 35 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	0.13963163395290357	[435]	[316,159,NaN]	0	hSpCas9	negative selection	9969329
3782802	3782825	16	+	27869803	HPAFII	viability after 35 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-2.118406668694261	[168]	[14,24,NaN]	-8	hSpCas9	negative selection	9969330
3793444	3793467	16	+	27869803	HPAFII	viability after 35 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-1.2268767393150124	[329]	[116,19,NaN]	-6	hSpCas9	negative selection	9969331
3810727	3810750	16	-	27869803	HPAFII	viability after 35 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.8337917491727378	[188]	[305,17,NaN]	5	hSpCas9	negative selection	9969332
3850580	3850603	16	-	27869803	HPAFII	viability after 35 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.7020275555035513	[96]	[48,8,NaN]	-4	hSpCas9	negative selection	9969333
3879855	3879878	16	-	27869803	HPAFII	viability after 35 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	-0.4878593728857302	[219]	[93,62,NaN]	-3	hSpCas9	negative selection	9969334
3780861	3780884	16	-	27869803	HPAFII	viability after 31 days	CTTAGCCCACTGATGAACGATGG	CREBBP	ENSG00000005339	-0.12621662118331778	[435]	[328,109,NaN]	-1	hSpCas9	negative selection	10051778
3782802	3782825	16	+	27869803	HPAFII	viability after 31 days	ATAGGCTCGCTGCATGGAGCTGG	CREBBP	ENSG00000005339	-1.9162514860799322	[168]	[27,21,NaN]	-8	hSpCas9	negative selection	10051779
3793444	3793467	16	+	27869803	HPAFII	viability after 31 days	TCGACAATGCGGGAGCGAGCAGG	CREBBP	ENSG00000005339	-0.7070382157855831	[329]	[156,65,NaN]	-4	hSpCas9	negative selection	10051780
3810727	3810750	16	-	27869803	HPAFII	viability after 31 days	GGACAGCCCTTTAGTCAAGCTGG	CREBBP	ENSG00000005339	0.5064592256159318	[188]	[243,48,NaN]	3	hSpCas9	negative selection	10051781
3850580	3850603	16	-	27869803	HPAFII	viability after 31 days	AGCCCTGCCACGTCACAGACTGG	CREBBP	ENSG00000005339	-0.04349022747040632	[96]	[59,44,NaN]	0	hSpCas9	negative selection	10051782
3879855	3879878	16	-	27869803	HPAFII	viability after 31 days	AGAGCCAAACTCAGCTCGCCCGG	CREBBP	ENSG00000005339	0.009196462669699978	[219]	[196,44,NaN]	0	hSpCas9	negative selection	10051783
3850949	3850972	16	-	28162770	P31FUJ	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.1893005657777921	[195]	[201]	-2	hSpCas9	negative selection	10137927
3850718	3850741	16	-	28162770	P31FUJ	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.5949418380017917	[270]	[480]	6	hSpCas9	negative selection	10137928
3770859	3770882	16	+	28162770	P31FUJ	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.9307736669647209	[145]	[44]	-8	hSpCas9	negative selection	10137929
3769221	3769244	16	-	28162770	P31FUJ	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.3358956973784821	[173]	[80]	-7	hSpCas9	negative selection	10137930
3736080	3736103	16	-	28162770	P31FUJ	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-0.6550352050974266	[66]	[49]	-5	hSpCas9	negative selection	10137931
3780795	3780818	16	-	28162770	P31FUJ	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.610558687613763	[190]	[146]	-5	hSpCas9	negative selection	10137932
3740466	3740489	16	-	28162770	P31FUJ	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	1.1427069306778277	[110]	[287]	9	hSpCas9	negative selection	10137933
3740424	3740447	16	-	28162770	P31FUJ	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.42378167311936515	[370]	[324]	-4	hSpCas9	negative selection	10137934
3731263	3731286	16	-	28162770	P31FUJ	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.47048026349553895	[155]	[253]	5	hSpCas9	negative selection	10137935
3850865	3850888	16	-	28162770	P31FUJ	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	2.15546838530168	[16]	[88]	9	hSpCas9	negative selection	10137936
3850949	3850972	16	-	28162770	TF1	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10307293
3850718	3850741	16	-	28162770	TF1	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10307294
3770859	3770882	16	+	28162770	TF1	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10307295
3769221	3769244	16	-	28162770	TF1	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10307296
3736080	3736103	16	-	28162770	TF1	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10307297
3780795	3780818	16	-	28162770	TF1	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	NaN	[NaN]	[279]	1	hSpCas9	negative selection	10307298
3740466	3740489	16	-	28162770	TF1	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10307299
3740424	3740447	16	-	28162770	TF1	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10307300
3731263	3731286	16	-	28162770	TF1	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10307301
3850865	3850888	16	-	28162770	TF1	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10307302
3850949	3850972	16	-	28162770	SKM1	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.05246741989413539	[71]	[131]	0	hSpCas9	negative selection	10476659
3850718	3850741	16	-	28162770	SKM1	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.19546009354944993	[56]	[87]	-2	hSpCas9	negative selection	10476660
3770859	3770882	16	+	28162770	SKM1	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.085036103855799	[47]	[9]	-9	hSpCas9	negative selection	10476661
3769221	3769244	16	-	28162770	SKM1	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-2.8517490414160576	[48]	[11]	-9	hSpCas9	negative selection	10476662
3736080	3736103	16	-	28162770	SKM1	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-3.484966710744435	[18]	[2]	-9	hSpCas9	negative selection	10476663
3780795	3780818	16	-	28162770	SKM1	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.7046447473838466	[58]	[63]	-5	hSpCas9	negative selection	10476664
3740466	3740489	16	-	28162770	SKM1	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.615550820554579	[25]	[29]	-5	hSpCas9	negative selection	10476665
3740424	3740447	16	-	28162770	SKM1	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-1.5969351423872322	[76]	[44]	-8	hSpCas9	negative selection	10476666
3731263	3731286	16	-	28162770	SKM1	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	-0.17814550824728073	[47]	[74]	-1	hSpCas9	negative selection	10476667
3850865	3850888	16	-	28162770	SKM1	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-2.4069641987431614	[11]	[3]	-8	hSpCas9	negative selection	10476668
3850949	3850972	16	-	28162770	SKM1	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.05246741989413539	[71]	[131]	0	hSpCas9	negative selection	10646025
3850718	3850741	16	-	28162770	SKM1	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.19546009354944993	[56]	[87]	-2	hSpCas9	negative selection	10646026
3770859	3770882	16	+	28162770	SKM1	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.085036103855799	[47]	[9]	-9	hSpCas9	negative selection	10646027
3769221	3769244	16	-	28162770	SKM1	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-2.8517490414160576	[48]	[11]	-9	hSpCas9	negative selection	10646028
3736080	3736103	16	-	28162770	SKM1	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-3.484966710744435	[18]	[2]	-9	hSpCas9	negative selection	10646029
3780795	3780818	16	-	28162770	SKM1	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.7046447473838466	[58]	[63]	-5	hSpCas9	negative selection	10646030
3740466	3740489	16	-	28162770	SKM1	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.615550820554579	[25]	[29]	-5	hSpCas9	negative selection	10646031
3740424	3740447	16	-	28162770	SKM1	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-1.5969351423872322	[76]	[44]	-8	hSpCas9	negative selection	10646032
3731263	3731286	16	-	28162770	SKM1	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	-0.17814550824728073	[47]	[74]	-1	hSpCas9	negative selection	10646033
3850865	3850888	16	-	28162770	SKM1	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-2.4069641987431614	[11]	[3]	-8	hSpCas9	negative selection	10646034
3850949	3850972	16	-	28162770	PL21	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	1.3746373457214567	[209]	[236]	9	hSpCas9	negative selection	10815391
3850718	3850741	16	-	28162770	PL21	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.47121133938853244	[178]	[107]	4	hSpCas9	negative selection	10815392
3770859	3770882	16	+	28162770	PL21	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	0.37125153088207463	[134]	[75]	3	hSpCas9	negative selection	10815393
3769221	3769244	16	-	28162770	PL21	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-2.4187702181551733	[171]	[13]	-8	hSpCas9	negative selection	10815394
3736080	3736103	16	-	28162770	PL21	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.4065904919567465	[103]	[59]	3	hSpCas9	negative selection	10815395
3780795	3780818	16	-	28162770	PL21	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	0.8231701560439958	[186]	[143]	7	hSpCas9	negative selection	10815396
3740466	3740489	16	-	28162770	PL21	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	0.5404797464905629	[108]	[68]	5	hSpCas9	negative selection	10815397
3740424	3740447	16	-	28162770	PL21	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	0.2813634097632928	[258]	[136]	2	hSpCas9	negative selection	10815398
3731263	3731286	16	-	28162770	PL21	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.7666294551389974	[130]	[96]	6	hSpCas9	negative selection	10815399
3850865	3850888	16	-	28162770	PL21	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	1.20013961448932	[32]	[32]	8	hSpCas9	negative selection	10815400
3850949	3850972	16	-	28162770	P31FUJ	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.1893005657777921	[195]	[201]	-2	hSpCas9	negative selection	10984757
3850718	3850741	16	-	28162770	P31FUJ	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.5949418380017917	[270]	[480]	6	hSpCas9	negative selection	10984758
3770859	3770882	16	+	28162770	P31FUJ	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.9307736669647209	[145]	[44]	-8	hSpCas9	negative selection	10984759
3769221	3769244	16	-	28162770	P31FUJ	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.3358956973784821	[173]	[80]	-7	hSpCas9	negative selection	10984760
3736080	3736103	16	-	28162770	P31FUJ	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-0.6550352050974266	[66]	[49]	-5	hSpCas9	negative selection	10984761
3780795	3780818	16	-	28162770	P31FUJ	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.610558687613763	[190]	[146]	-5	hSpCas9	negative selection	10984762
3740466	3740489	16	-	28162770	P31FUJ	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	1.1427069306778277	[110]	[287]	9	hSpCas9	negative selection	10984763
3740424	3740447	16	-	28162770	P31FUJ	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.42378167311936515	[370]	[324]	-4	hSpCas9	negative selection	10984764
3731263	3731286	16	-	28162770	P31FUJ	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.47048026349553895	[155]	[253]	5	hSpCas9	negative selection	10984765
3850865	3850888	16	-	28162770	P31FUJ	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	2.15546838530168	[16]	[88]	9	hSpCas9	negative selection	10984766
3850949	3850972	16	-	28162770	OCIAML5	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.17077340549411427	[93]	[190]	1	hSpCas9	negative selection	11154123
3850718	3850741	16	-	28162770	OCIAML5	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.3045787755615037	[181]	[265]	-2	hSpCas9	negative selection	11154124
3770859	3770882	16	+	28162770	OCIAML5	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-2.0537004320336476	[91]	[39]	-8	hSpCas9	negative selection	11154125
3769221	3769244	16	-	28162770	OCIAML5	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.07735888270624	[82]	[70]	-6	hSpCas9	negative selection	11154126
3736080	3736103	16	-	28162770	OCIAML5	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-4.910960259917566	[49]	[2]	-9	hSpCas9	negative selection	11154127
3780795	3780818	16	-	28162770	OCIAML5	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	1.4514242757666889	[62]	[310]	9	hSpCas9	negative selection	11154128
3740466	3740489	16	-	28162770	OCIAML5	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-1.8699884788612595	[80]	[39]	-7	hSpCas9	negative selection	11154129
3740424	3740447	16	-	28162770	OCIAML5	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-1.3141015496800101	[207]	[150]	-6	hSpCas9	negative selection	11154130
3731263	3731286	16	-	28162770	OCIAML5	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.25686780068916704	[101]	[219]	2	hSpCas9	negative selection	11154131
3850865	3850888	16	-	28162770	OCIAML5	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-0.7696044106720241	[16]	[17]	-5	hSpCas9	negative selection	11154132
3850949	3850972	16	-	28162770	EOL1	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.22594385495691593	[423]	[190]	-2	hSpCas9	negative selection	11323489
3850718	3850741	16	-	28162770	EOL1	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.448567508066384	[273]	[196]	4	hSpCas9	negative selection	11323490
3770859	3770882	16	+	28162770	EOL1	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	0.4888508017255977	[210]	[155]	4	hSpCas9	negative selection	11323491
3769221	3769244	16	-	28162770	EOL1	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-0.7168401626134406	[364]	[116]	-5	hSpCas9	negative selection	11323492
3736080	3736103	16	-	28162770	EOL1	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.4662570743378067	[157]	[114]	4	hSpCas9	negative selection	11323493
3780795	3780818	16	-	28162770	EOL1	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.49159566493447865	[434]	[162]	-4	hSpCas9	negative selection	11323494
3740466	3740489	16	-	28162770	EOL1	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	2.8064920100488226	[104]	[386]	9	hSpCas9	negative selection	11323495
3740424	3740447	16	-	28162770	EOL1	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.16590717937496896	[361]	[169]	-1	hSpCas9	negative selection	11323496
3731263	3731286	16	-	28162770	EOL1	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.6372658194900636	[215]	[176]	5	hSpCas9	negative selection	11323497
3850865	3850888	16	-	28162770	EOL1	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	0.8120730423121221	[39]	[36]	7	hSpCas9	negative selection	11323498
3850949	3850972	16	-	28162770	MOLM13	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.11046260543583025	[359]	[280]	0	hSpCas9	negative selection	11492855
3850718	3850741	16	-	28162770	MOLM13	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.1307480560736538	[264]	[174]	-1	hSpCas9	negative selection	11492856
3770859	3770882	16	+	28162770	MOLM13	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.524576945770013	[190]	[11]	-8	hSpCas9	negative selection	11492857
3769221	3769244	16	-	28162770	MOLM13	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-4.298823556015679	[244]	[8]	-9	hSpCas9	negative selection	11492858
3736080	3736103	16	-	28162770	MOLM13	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-1.996391636754114	[148]	[26]	-7	hSpCas9	negative selection	11492859
3780795	3780818	16	-	28162770	MOLM13	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.75279873357962	[281]	[120]	-4	hSpCas9	negative selection	11492860
3740466	3740489	16	-	28162770	MOLM13	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	0.5047261497249501	[115]	[118]	4	hSpCas9	negative selection	11492861
3740424	3740447	16	-	28162770	MOLM13	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-1.1687352389990702	[397]	[127]	-6	hSpCas9	negative selection	11492862
3731263	3731286	16	-	28162770	MOLM13	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.023705536606218602	[199]	[146]	0	hSpCas9	negative selection	11492863
3850865	3850888	16	-	28162770	MOLM13	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-1.5321106184554218	[31]	[7]	-6	hSpCas9	negative selection	11492864
3850949	3850972	16	-	28162770	HEL	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.4154241935577817	[328]	[157]	-3	hSpCas9	negative selection	11662221
3850718	3850741	16	-	28162770	HEL	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-1.0166058650433756	[198]	[62]	-6	hSpCas9	negative selection	11662222
3770859	3770882	16	+	28162770	HEL	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-3.0830862045606486	[171]	[12]	-9	hSpCas9	negative selection	11662223
3769221	3769244	16	-	28162770	HEL	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.7666521041373446	[169]	[31]	-7	hSpCas9	negative selection	11662224
3736080	3736103	16	-	28162770	HEL	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-2.4117089520220194	[107]	[12]	-8	hSpCas9	negative selection	11662225
3780795	3780818	16	-	28162770	HEL	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-1.4561468325101006	[316]	[73]	-7	hSpCas9	negative selection	11662226
3740466	3740489	16	-	28162770	HEL	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-1.5522771504047863	[86]	[18]	-7	hSpCas9	negative selection	11662227
3740424	3740447	16	-	28162770	HEL	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-3.674673781764512	[318]	[15]	-9	hSpCas9	negative selection	11662228
3731263	3731286	16	-	28162770	HEL	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.5711855709753229	[185]	[176]	5	hSpCas9	negative selection	11662229
3850865	3850888	16	-	28162770	HEL	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	0.45009375405796126	[31]	[27]	4	hSpCas9	negative selection	11662230
3850949	3850972	16	-	28162770	MV411	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.6571612501651511	[203]	[270]	6	hSpCas9	negative selection	11831587
3850718	3850741	16	-	28162770	MV411	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.015767315858316675	[181]	[154]	0	hSpCas9	negative selection	11831588
3770859	3770882	16	+	28162770	MV411	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.570185706728656	[140]	[39]	-7	hSpCas9	negative selection	11831589
3769221	3769244	16	-	28162770	MV411	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.5074499513806934	[134]	[39]	-7	hSpCas9	negative selection	11831590
3736080	3736103	16	-	28162770	MV411	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.9079510845111083	[61]	[97]	7	hSpCas9	negative selection	11831591
3780795	3780818	16	-	28162770	MV411	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	0.10924025686275579	[207]	[188]	0	hSpCas9	negative selection	11831592
3740466	3740489	16	-	28162770	MV411	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	0.6405824442127769	[82]	[108]	6	hSpCas9	negative selection	11831593
3740424	3740447	16	-	28162770	MV411	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	0.15961967199135818	[253]	[238]	1	hSpCas9	negative selection	11831594
3731263	3731286	16	-	28162770	MV411	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.09769043127809329	[141]	[127]	0	hSpCas9	negative selection	11831595
3850865	3850888	16	-	28162770	MV411	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	1.3088380954469188	[22]	[47]	9	hSpCas9	negative selection	11831596
3850949	3850972	16	-	28162770	MONOMAC1	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	1.370395729104026	[137]	[408]	9	hSpCas9	negative selection	12000953
3850718	3850741	16	-	28162770	MONOMAC1	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.9366875126671874	[138]	[304]	8	hSpCas9	negative selection	12000954
3770859	3770882	16	+	28162770	MONOMAC1	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-1.5122390787586026	[106]	[42]	-8	hSpCas9	negative selection	12000955
3769221	3769244	16	-	28162770	MONOMAC1	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-0.78199934778071	[128]	[85]	-6	hSpCas9	negative selection	12000956
3736080	3736103	16	-	28162770	MONOMAC1	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	0.32652510899745923	[63]	[91]	3	hSpCas9	negative selection	12000957
3780795	3780818	16	-	28162770	MONOMAC1	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	1.1688345954154058	[96]	[249]	8	hSpCas9	negative selection	12000958
3740466	3740489	16	-	28162770	MONOMAC1	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	0.6729026123760733	[57]	[105]	6	hSpCas9	negative selection	12000959
3740424	3740447	16	-	28162770	MONOMAC1	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	0.8300992828779601	[157]	[321]	7	hSpCas9	negative selection	12000960
3731263	3731286	16	-	28162770	MONOMAC1	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.43099437555348846	[65]	[101]	4	hSpCas9	negative selection	12000961
3850865	3850888	16	-	28162770	MONOMAC1	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	1.1721969626061655	[11]	[30]	8	hSpCas9	negative selection	12000962
3850949	3850972	16	-	28162770	OCIAML2	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	0.2642733024671525	[34]	[232]	2	hSpCas9	negative selection	12170319
3850718	3850741	16	-	28162770	OCIAML2	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	0.5724388966497247	[32]	[271]	5	hSpCas9	negative selection	12170320
3770859	3770882	16	+	28162770	OCIAML2	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-2.307131092959282	[24]	[27]	-8	hSpCas9	negative selection	12170321
3769221	3769244	16	-	28162770	OCIAML2	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-1.7116379247459563	[25]	[43]	-8	hSpCas9	negative selection	12170322
3736080	3736103	16	-	28162770	OCIAML2	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-0.544630406685938	[19]	[75]	-4	hSpCas9	negative selection	12170323
3780795	3780818	16	-	28162770	OCIAML2	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	0.024134866507416815	[32]	[185]	0	hSpCas9	negative selection	12170324
3740466	3740489	16	-	28162770	OCIAML2	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.200540661874417	[16]	[81]	-2	hSpCas9	negative selection	12170325
3740424	3740447	16	-	28162770	OCIAML2	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-2.5261249378338646	[52]	[50]	-8	hSpCas9	negative selection	12170326
3731263	3731286	16	-	28162770	OCIAML2	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.29653600669974395	[25]	[176]	3	hSpCas9	negative selection	12170327
3850865	3850888	16	-	28162770	OCIAML2	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-2.470629825242162	[6]	[6]	-8	hSpCas9	negative selection	12170328
3850949	3850972	16	-	28162770	OCIAML3	viability	GATGAGCTGATACCCAATGGAGG	CREBBP	ENSG00000005339	-0.8503473935839487	[85]	[143]	-6	hSpCas9	negative selection	12339685
3850718	3850741	16	-	28162770	OCIAML3	viability	GGCAAGAGCCCTCTGAGCCAGGG	CREBBP	ENSG00000005339	-0.6871170447156447	[55]	[104]	-5	hSpCas9	negative selection	12339686
3770859	3770882	16	+	28162770	OCIAML3	viability	GCAGCCGTGGAAGCAGGAGGCGG	CREBBP	ENSG00000005339	-2.246084336903856	[32]	[20]	-8	hSpCas9	negative selection	12339687
3769221	3769244	16	-	28162770	OCIAML3	viability	GAAGACGGAGACCCAAGCAGAGG	CREBBP	ENSG00000005339	-0.48079702987617223	[48]	[105]	-4	hSpCas9	negative selection	12339688
3736080	3736103	16	-	28162770	OCIAML3	viability	GGAACTAGAACAAGAAGAAGAGG	CREBBP	ENSG00000005339	-0.25697265304659256	[18]	[47]	-2	hSpCas9	negative selection	12339689
3780795	3780818	16	-	28162770	OCIAML3	viability	GCAGCTCCTCCTTCTAGCACCGG	CREBBP	ENSG00000005339	-0.7460107337692132	[64]	[116]	-5	hSpCas9	negative selection	12339690
3740466	3740489	16	-	28162770	OCIAML3	viability	CCAGAATCACCCTGAAGCCGGGG	CREBBP	ENSG00000005339	-0.1159603435195189	[13]	[38]	-1	hSpCas9	negative selection	12339691
3740424	3740447	16	-	28162770	OCIAML3	viability	GGCCAGCTCAGACAAGACGGTGG	CREBBP	ENSG00000005339	-0.291444870303732	[89]	[221]	-2	hSpCas9	negative selection	12339692
3731263	3731286	16	-	28162770	OCIAML3	viability	GGAGCTGCACACCCAGGGCCAGG	CREBBP	ENSG00000005339	0.17381891754680362	[36]	[125]	1	hSpCas9	negative selection	12339693
3850865	3850888	16	-	28162770	OCIAML3	viability	CTGTCGGAGCTTCTACGAGGAGG	CREBBP	ENSG00000005339	-3.5940076403241634	[3]	[0]	-9	hSpCas9	negative selection	12339694