Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1024
• Symbol: Cdk8
• Description: cyclin dependent kinase 8

DataSource: http://genomecrispr.dkfz.de/#!/results/Cdk8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
26254708	26254731	13	+	26472758	Jiyoye	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	28892
26400493	26400516	13	-	26472758	Jiyoye	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	-0.07680947149046169	[399]	[285]	0	hSpCas9	negative selection	28893
26254690	26254713	13	+	26472758	Jiyoye	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.16750496873759002	[195]	[165]	1	hSpCas9	negative selection	28894
26353778	26353801	13	+	26472758	Jiyoye	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.5249156504343786	[293]	[318]	4	hSpCas9	negative selection	28895
26254659	26254682	13	+	26472758	Jiyoye	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	1.8270786359565332	[36]	[98]	8	hSpCas9	negative selection	28896
26353794	26353817	13	-	26472758	Jiyoye	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.26141669119431343	[332]	[300]	2	hSpCas9	negative selection	28897
26254739	26254762	13	+	26472758	Jiyoye	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	-0.25465588259955324	[105]	[66]	-2	hSpCas9	negative selection	28898
26353847	26353870	13	-	26472758	Jiyoye	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.4637589098722406	[24]	[51]	8	hSpCas9	negative selection	28899
26393489	26393512	13	+	26472758	Jiyoye	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	-0.18683225881828958	[79]	[52]	-1	hSpCas9	negative selection	28900
26400482	26400505	13	+	26472758	Jiyoye	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-0.7627496199364389	[62]	[27]	-5	hSpCas9	negative selection	28901
26254708	26254731	13	+	26472758	KBM7	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.9257965983880139	[29,12]	[36,1]	8	hSpCas9	negative selection	220010
26400493	26400516	13	-	26472758	KBM7	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.4179800121934232	[1323,1302]	[828,827]	4	hSpCas9	negative selection	220011
26254690	26254713	13	+	26472758	KBM7	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.35164991908410925	[691,594]	[441,333]	4	hSpCas9	negative selection	220012
26353778	26353801	13	+	26472758	KBM7	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.7279045449555432	[1366,1145]	[1220,753]	7	hSpCas9	negative selection	220013
26254659	26254682	13	+	26472758	KBM7	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	0.9140996294954526	[309,221]	[216,246]	8	hSpCas9	negative selection	220014
26353794	26353817	13	-	26472758	KBM7	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.6721128549617497	[969,873]	[700,680]	7	hSpCas9	negative selection	220015
26254739	26254762	13	+	26472758	KBM7	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.5849172084270562	[483,711]	[459,406]	6	hSpCas9	negative selection	220016
26353847	26353870	13	-	26472758	KBM7	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.9441622921128153	[369,343]	[316,328]	8	hSpCas9	negative selection	220017
26393489	26393512	13	+	26472758	KBM7	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	1.080608155184166	[605,420]	[631,388]	9	hSpCas9	negative selection	220018
26400482	26400505	13	+	26472758	KBM7	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.12839267049383815	[417,381]	[221,190]	1	hSpCas9	negative selection	220019
26254708	26254731	13	+	26472758	Raji	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.5224210346524432	[2]	[0]	5	hSpCas9	negative selection	411128
26400493	26400516	13	-	26472758	Raji	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	-0.35115560254183076	[807]	[146]	-3	hSpCas9	negative selection	411129
26254690	26254713	13	+	26472758	Raji	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.46692592206073985	[264]	[84]	4	hSpCas9	negative selection	411130
26353778	26353801	13	+	26472758	Raji	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.06449772252042307	[477]	[115]	0	hSpCas9	negative selection	411131
26254659	26254682	13	+	26472758	Raji	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.35204808326369796	[164]	[29]	-3	hSpCas9	negative selection	411132
26353794	26353817	13	-	26472758	Raji	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.2865327708317724	[536]	[151]	2	hSpCas9	negative selection	411133
26254739	26254762	13	+	26472758	Raji	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	-0.22094233071191344	[225]	[44]	-2	hSpCas9	negative selection	411134
26353847	26353870	13	-	26472758	Raji	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.3783448569790224	[120]	[72]	9	hSpCas9	negative selection	411135
26393489	26393512	13	+	26472758	Raji	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	-0.8634701189668841	[391]	[49]	-6	hSpCas9	negative selection	411136
26400482	26400505	13	+	26472758	Raji	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.8301552479570515	[142]	[58]	7	hSpCas9	negative selection	411137
26254708	26254731	13	+	26472758	K562	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-3.562936194391156	[13]	[0]	-8	hSpCas9	negative selection	602246
26400493	26400516	13	-	26472758	K562	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	-0.2655590580296382	[805]	[565]	-2	hSpCas9	negative selection	602247
26254690	26254713	13	+	26472758	K562	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.017475658320678	[505]	[210]	-5	hSpCas9	negative selection	602248
26353778	26353801	13	+	26472758	K562	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	-0.9650346379625031	[850]	[367]	-5	hSpCas9	negative selection	602249
26254659	26254682	13	+	26472758	K562	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-1.5369409858582128	[219]	[63]	-6	hSpCas9	negative selection	602250
26353794	26353817	13	-	26472758	K562	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	-1.1811880133225843	[684]	[254]	-6	hSpCas9	negative selection	602251
26254739	26254762	13	+	26472758	K562	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	-0.9265674691461759	[339]	[150]	-5	hSpCas9	negative selection	602252
26353847	26353870	13	-	26472758	K562	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.40616979766305905	[176]	[197]	3	hSpCas9	negative selection	602253
26393489	26393512	13	+	26472758	K562	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	-0.8823384146194919	[320]	[146]	-5	hSpCas9	negative selection	602254
26400482	26400505	13	+	26472758	K562	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-1.3156691044156803	[229]	[77]	-6	hSpCas9	negative selection	602255
26254690	26254713	13	+	26627737	DLD1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.3951380537332638	[269]	[41,54,90]	-4	hSpCas9	negative selection	786519
26254695	26254718	13	-	26627737	DLD1	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.7907482081465074	[998]	[830,397,405]	7	hSpCas9	negative selection	786520
26349176	26349199	13	-	26627737	DLD1	viability	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.4117258100018929	[856]	[237,464,368]	4	hSpCas9	negative selection	786521
26385301	26385324	13	+	26627737	DLD1	viability	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.26730922502636423	[1199]	[534,459,371]	2	hSpCas9	negative selection	786522
26393455	26393478	13	+	26627737	DLD1	viability	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	1.0436892933366118	[232]	[52,251,149]	8	hSpCas9	negative selection	786523
26254690	26254713	13	+	26627737	GBM cells	viability after 5 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.5085104402832832	[125]	[39,54]	-7	hSpCas9	negative selection	868834
26254695	26254718	13	-	26627737	GBM cells	viability after 5 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.44089930286156664	[635]	[447,477]	6	hSpCas9	negative selection	868835
26349176	26349199	13	-	26627737	GBM cells	viability after 5 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.37862010064322327	[479]	[208,186]	-5	hSpCas9	negative selection	868836
26385301	26385324	13	+	26627737	GBM cells	viability after 5 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.4510002193601528	[576]	[421,423]	6	hSpCas9	negative selection	868837
26393455	26393478	13	+	26627737	GBM cells	viability after 5 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.47634270292143444	[127]	[116,73]	7	hSpCas9	negative selection	868838
26254690	26254713	13	+	26627737	GBM cells	viability after 13 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.6493099088659746	[125]	[47,39]	-6	hSpCas9	negative selection	951149
26254695	26254718	13	-	26627737	GBM cells	viability after 13 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.37484550985854415	[635]	[554,359]	5	hSpCas9	negative selection	951150
26349176	26349199	13	-	26627737	GBM cells	viability after 13 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.1872059136008194	[479]	[193,256]	-2	hSpCas9	negative selection	951151
26385301	26385324	13	+	26627737	GBM cells	viability after 13 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.3915082653126478	[576]	[365,446]	5	hSpCas9	negative selection	951152
26393455	26393478	13	+	26627737	GBM cells	viability after 13 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.5240485993121272	[127]	[111,89]	6	hSpCas9	negative selection	951153
26254690	26254713	13	+	26627737	GBM cells	viability after 21 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.6633452803403785	[125]	[37,47]	-5	hSpCas9	negative selection	1033464
26254695	26254718	13	-	26627737	GBM cells	viability after 21 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3941106655615003	[635]	[475,433]	4	hSpCas9	negative selection	1033465
26349176	26349199	13	-	26627737	GBM cells	viability after 21 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.04138458173941284	[479]	[243,261]	0	hSpCas9	negative selection	1033466
26385301	26385324	13	+	26627737	GBM cells	viability after 21 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.849884476409857	[576]	[576,553]	8	hSpCas9	negative selection	1033467
26393455	26393478	13	+	26627737	GBM cells	viability after 21 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.740423629081417	[127]	[111,119]	7	hSpCas9	negative selection	1033468
26254690	26254713	13	+	26627737	RPE1	viability after 9 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.022812860533584	[744]	[71,169]	-6	hSpCas9	negative selection	1115779
26254695	26254718	13	-	26627737	RPE1	viability after 9 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.8219251358089508	[2059]	[957,1374]	5	hSpCas9	negative selection	1115780
26349176	26349199	13	-	26627737	RPE1	viability after 9 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.5212983665590377	[1066]	[416,559]	3	hSpCas9	negative selection	1115781
26385301	26385324	13	+	26627737	RPE1	viability after 9 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.867940487438825	[2016]	[1189,1103]	5	hSpCas9	negative selection	1115782
26393455	26393478	13	+	26627737	RPE1	viability after 9 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-1.3028620821330974	[740]	[76,115]	-7	hSpCas9	negative selection	1115783
26254690	26254713	13	+	26627737	RPE1	viability after 12 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.7539827197767047	[744]	[56,183]	-5	hSpCas9	negative selection	1198094
26254695	26254718	13	-	26627737	RPE1	viability after 12 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.128474121764514	[2059]	[1294,1119]	6	hSpCas9	negative selection	1198095
26349176	26349199	13	-	26627737	RPE1	viability after 12 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.9985107019598727	[1066]	[495,653]	6	hSpCas9	negative selection	1198096
26385301	26385324	13	+	26627737	RPE1	viability after 12 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.7374283986686077	[2016]	[901,904]	5	hSpCas9	negative selection	1198097
26393455	26393478	13	+	26627737	RPE1	viability after 12 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.8922884027467881	[740]	[132,79]	-6	hSpCas9	negative selection	1198098
26254690	26254713	13	+	26627737	RPE1	viability after 15 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.0536902822030216	[744]	[43,156]	-6	hSpCas9	negative selection	1280409
26254695	26254718	13	-	26627737	RPE1	viability after 15 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.2844459955084313	[2059]	[1702,1145]	7	hSpCas9	negative selection	1280410
26349176	26349199	13	-	26627737	RPE1	viability after 15 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.8715082345669123	[1066]	[370,726]	5	hSpCas9	negative selection	1280411
26385301	26385324	13	+	26627737	RPE1	viability after 15 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.7517181062434084	[2016]	[1032,890]	4	hSpCas9	negative selection	1280412
26393455	26393478	13	+	26627737	RPE1	viability after 15 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.7007584990079793	[740]	[130,126]	-4	hSpCas9	negative selection	1280413
26254690	26254713	13	+	26627737	RPE1	viability after 18 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.7287277105569944	[744]	[86,157]	-4	hSpCas9	negative selection	1362724
26254695	26254718	13	-	26627737	RPE1	viability after 18 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.154825349719396	[2059]	[1319,1149]	6	hSpCas9	negative selection	1362725
26349176	26349199	13	-	26627737	RPE1	viability after 18 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.3248144858379425	[1066]	[715,726]	7	hSpCas9	negative selection	1362726
26385301	26385324	13	+	26627737	RPE1	viability after 18 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.884400929781173	[2016]	[1057,947]	5	hSpCas9	negative selection	1362727
26393455	26393478	13	+	26627737	RPE1	viability after 18 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.547077452226248	[740]	[161,109]	-3	hSpCas9	negative selection	1362728
26254690	26254713	13	+	26627737	HeLa	viability after 8 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.2323006555623275	[232]	[111,9,23]	-8	hSpCas9	negative selection	1445039
26254695	26254718	13	-	26627737	HeLa	viability after 8 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.049163513419128835	[1467]	[735,476,661]	0	hSpCas9	negative selection	1445040
26349176	26349199	13	-	26627737	HeLa	viability after 8 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.09141595209401532	[600]	[344,133,276]	-1	hSpCas9	negative selection	1445041
26385301	26385324	13	+	26627737	HeLa	viability after 8 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.5415870312580715	[662]	[526,449,313]	5	hSpCas9	negative selection	1445042
26393455	26393478	13	+	26627737	HeLa	viability after 8 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.925787006256515	[325]	[133,56,47]	-7	hSpCas9	negative selection	1445043
26254690	26254713	13	+	26627737	HeLa	viability after 12 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.7007981486887142	[232]	[104,21,55]	-6	hSpCas9	negative selection	1527354
26254695	26254718	13	-	26627737	HeLa	viability after 12 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.18102644254185196	[1467]	[615,494,500]	-1	hSpCas9	negative selection	1527355
26349176	26349199	13	-	26627737	HeLa	viability after 12 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.4171171315384278	[600]	[176,363,445]	3	hSpCas9	negative selection	1527356
26385301	26385324	13	+	26627737	HeLa	viability after 12 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.7583628377241498	[662]	[403,658,304]	6	hSpCas9	negative selection	1527357
26393455	26393478	13	+	26627737	HeLa	viability after 12 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.044564814499737676	[325]	[209,90,122]	0	hSpCas9	negative selection	1527358
26254690	26254713	13	+	26627737	HeLa	viability after 15 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.4185442025917291	[232]	[51,91,68]	-4	hSpCas9	negative selection	1609669
26254695	26254718	13	-	26627737	HeLa	viability after 15 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.012991348717923845	[1467]	[606,608,557]	0	hSpCas9	negative selection	1609670
26349176	26349199	13	-	26627737	HeLa	viability after 15 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.16896268104057488	[600]	[298,96,258]	-1	hSpCas9	negative selection	1609671
26385301	26385324	13	+	26627737	HeLa	viability after 15 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.8478074729870893	[662]	[510,592,341]	6	hSpCas9	negative selection	1609672
26393455	26393478	13	+	26627737	HeLa	viability after 15 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.023580904747684706	[325]	[132,123,134]	0	hSpCas9	negative selection	1609673
26254690	26254713	13	+	26627737	HeLa	viability after 18 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.3297127716440976	[232]	[38,81,68]	-3	hSpCas9	negative selection	1691984
26254695	26254718	13	-	26627737	HeLa	viability after 18 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.01912982427117549	[1467]	[404,500,557]	0	hSpCas9	negative selection	1691985
26349176	26349199	13	-	26627737	HeLa	viability after 18 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.16377181306292315	[600]	[195,87,258]	-1	hSpCas9	negative selection	1691986
26385301	26385324	13	+	26627737	HeLa	viability after 18 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.8369572060945092	[662]	[330,496,341]	6	hSpCas9	negative selection	1691987
26393455	26393478	13	+	26627737	HeLa	viability after 18 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.03143491902851586	[325]	[85,104,134]	0	hSpCas9	negative selection	1691988
26254690	26254713	13	+	26627737	HCT116	viability after 6 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.6129456770758516	[327]	[5,48]	-4	hSpCas9	negative selection	1774299
26254695	26254718	13	-	26627737	HCT116	viability after 6 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.42600622023458246	[1945]	[393,135]	-2	hSpCas9	negative selection	1774300
26349176	26349199	13	-	26627737	HCT116	viability after 6 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.4819833202519088	[995]	[500,62]	2	hSpCas9	negative selection	1774301
26385301	26385324	13	+	26627737	HCT116	viability after 6 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	1.3245220322677569	[1432]	[783,442]	7	hSpCas9	negative selection	1774302
26393455	26393478	13	+	26627737	HCT116	viability after 6 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	2.9192805428864004	[121]	[30,207]	9	hSpCas9	negative selection	1774303
26254690	26254713	13	+	26627737	HCT116	viability after 8 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.44321633920542136	[168]	[89,58,56]	-5	hSpCas9	negative selection	1856614
26254695	26254718	13	-	26627737	HCT116	viability after 8 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.482812365675789	[667]	[499,618,424]	5	hSpCas9	negative selection	1856615
26349176	26349199	13	-	26627737	HCT116	viability after 8 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.7609527787977459	[634]	[148,228,239]	-7	hSpCas9	negative selection	1856616
26385301	26385324	13	+	26627737	HCT116	viability after 8 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.06901554189729175	[580]	[411,354,242]	0	hSpCas9	negative selection	1856617
26393455	26393478	13	+	26627737	HCT116	viability after 8 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.12476603707382128	[132]	[72,119,46]	1	hSpCas9	negative selection	1856618
26254690	26254713	13	+	26627737	HCT116	viability after 9 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.1684936422032717	[327]	[24,49]	-7	hSpCas9	negative selection	1938929
26254695	26254718	13	-	26627737	HCT116	viability after 9 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.888175544762353	[1945]	[244,308]	-6	hSpCas9	negative selection	1938930
26349176	26349199	13	-	26627737	HCT116	viability after 9 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.6982196889333816	[995]	[502,374]	5	hSpCas9	negative selection	1938931
26385301	26385324	13	+	26627737	HCT116	viability after 9 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.12416399292047053	[1432]	[535,322]	1	hSpCas9	negative selection	1938932
26393455	26393478	13	+	26627737	HCT116	viability after 9 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.7276951134988929	[121]	[63,45]	5	hSpCas9	negative selection	1938933
26254690	26254713	13	+	26627737	HCT116	viability after 12 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.9221137614247059	[168]	[59,27,50]	-7	hSpCas9	negative selection	2021244
26254695	26254718	13	-	26627737	HCT116	viability after 12 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.5509150390240758	[667]	[666,535,326]	5	hSpCas9	negative selection	2021245
26349176	26349199	13	-	26627737	HCT116	viability after 12 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.6240378339020098	[634]	[229,199,217]	-6	hSpCas9	negative selection	2021246
26385301	26385324	13	+	26627737	HCT116	viability after 12 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	-0.25524194879461304	[580]	[300,317,145]	-3	hSpCas9	negative selection	2021247
26393455	26393478	13	+	26627737	HCT116	viability after 12 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.6906832921248727	[132]	[51,162,129]	6	hSpCas9	negative selection	2021248
26254690	26254713	13	+	26627737	HCT116	viability after 15 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.19687918170108532	[168]	[82,100,69]	-2	hSpCas9	negative selection	2103559
26254695	26254718	13	-	26627737	HCT116	viability after 15 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3707866827171542	[667]	[583,512,402]	3	hSpCas9	negative selection	2103560
26349176	26349199	13	-	26627737	HCT116	viability after 15 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.5381101821287962	[634]	[246,343,162]	-5	hSpCas9	negative selection	2103561
26385301	26385324	13	+	26627737	HCT116	viability after 15 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.08916900849210463	[580]	[283,484,287]	0	hSpCas9	negative selection	2103562
26393455	26393478	13	+	26627737	HCT116	viability after 15 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.38565494366722797	[132]	[92,143,61]	4	hSpCas9	negative selection	2103563
26254690	26254713	13	+	26627737	HCT116	viability after 18 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.3339602333997091	[168]	[64,20,10]	-8	hSpCas9	negative selection	2185874
26254695	26254718	13	-	26627737	HCT116	viability after 18 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.24040343001204434	[667]	[506,282,359]	2	hSpCas9	negative selection	2185875
26349176	26349199	13	-	26627737	HCT116	viability after 18 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-0.47370869603783294	[634]	[276,216,166]	-4	hSpCas9	negative selection	2185876
26385301	26385324	13	+	26627737	HCT116	viability after 18 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	-0.271108440839933	[580]	[215,147,344]	-2	hSpCas9	negative selection	2185877
26393455	26393478	13	+	26627737	HCT116	viability after 18 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.2894305229760099	[132]	[44,79,29]	-3	hSpCas9	negative selection	2185878
26254658	26254681	13	+	24336569	HL60	viability	AAGTGAAGCTGAGCAGCGAGCGG	CDK8	ENSG00000132964	0.01889620572005679	[582]	[1249]	0	hSpCas9	negative selection	2256759
26254664	26254687	13	+	24336569	HL60	viability	AGCTGAGCAGCGAGCGGGAGCGG	CDK8	ENSG00000132964	0.6607957932068227	[951]	[3184]	5	hSpCas9	negative selection	2256760
26254671	26254694	13	+	24336569	HL60	viability	CAGCGAGCGGGAGCGGGTCGAGG	CDK8	ENSG00000132964	0.45946563202959373	[498]	[1451]	4	hSpCas9	negative selection	2256761
26254689	26254712	13	+	24336569	HL60	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.32065176450832233	[935]	[1585]	-3	hSpCas9	negative selection	2256762
26254695	26254718	13	-	24336569	HL60	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.49640897530594036	[271]	[811]	4	hSpCas9	negative selection	2256763
26254702	26254725	13	+	24336569	HL60	viability	GAATACGAGGGCTGCAAAGTTGG	CDK8	ENSG00000132964	0.12016976054075434	[1199]	[2759]	1	hSpCas9	negative selection	2256764
26254708	26254731	13	+	24336569	HL60	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-0.7532575592232321	[320]	[402]	-6	hSpCas9	negative selection	2256765
26254717	26254740	13	+	24336569	HL60	viability	AAAGTTGGCCGAGGCACTTATGG	CDK8	ENSG00000132964	0.9508234158729034	[717]	[2936]	7	hSpCas9	negative selection	2256766
26254725	26254748	13	-	24336569	HL60	viability	AGACGTGACCATAAGTGCCTCGG	CDK8	ENSG00000132964	-1.1434983791230802	[593]	[568]	-8	hSpCas9	negative selection	2256767
26254739	26254762	13	+	24336569	HL60	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.2977213118676665	[1481]	[3854]	3	hSpCas9	negative selection	2256768
26254658	26254681	13	+	24336569	KBM7	viability	AAGTGAAGCTGAGCAGCGAGCGG	CDK8	ENSG00000132964	-0.01819805532640595	[612]	[1650]	0	hSpCas9	negative selection	2323936
26254664	26254687	13	+	24336569	KBM7	viability	AGCTGAGCAGCGAGCGGGAGCGG	CDK8	ENSG00000132964	0.2658387026123554	[1012]	[3321]	2	hSpCas9	negative selection	2323937
26254671	26254694	13	+	24336569	KBM7	viability	CAGCGAGCGGGAGCGGGTCGAGG	CDK8	ENSG00000132964	-0.5489812287570957	[662]	[1235]	-4	hSpCas9	negative selection	2323938
26254689	26254712	13	+	24336569	KBM7	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.39684071405512905	[515]	[1852]	3	hSpCas9	negative selection	2323939
26254695	26254718	13	-	24336569	KBM7	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.8825305556586972	[210]	[1060]	7	hSpCas9	negative selection	2323940
26254702	26254725	13	+	24336569	KBM7	viability	GAATACGAGGGCTGCAAAGTTGG	CDK8	ENSG00000132964	-0.4571440605844166	[1134]	[2254]	-4	hSpCas9	negative selection	2323941
26254708	26254731	13	+	24336569	KBM7	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.7467347017541319	[188]	[864]	6	hSpCas9	negative selection	2323942
26254717	26254740	13	+	24336569	KBM7	viability	AAAGTTGGCCGAGGCACTTATGG	CDK8	ENSG00000132964	0.6225270001393911	[727]	[3056]	5	hSpCas9	negative selection	2323943
26254725	26254748	13	-	24336569	KBM7	viability	AGACGTGACCATAAGTGCCTCGG	CDK8	ENSG00000132964	-0.01139392240384024	[363]	[984]	0	hSpCas9	negative selection	2323944
26254739	26254762	13	+	24336569	KBM7	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.673345585710724	[1280]	[5571]	6	hSpCas9	negative selection	2323945
26335918	26335941	13	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTTGTTGTTGTTGTTGTTAAG	CDK8	ENSG00000132964	-1.2553913082042603	[104,179]	[19,4]	-7	dCas9-VP64	positive selection	2401223
26254446	26254469	13	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGACATCCAGGGGGACGGCGGG	CDK8	ENSG00000132964	3.1320564667486255	[31,1]	[40,21]	8	dCas9-VP64	positive selection	2417472
26254496	26254519	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCCGCATCAGTCGGGCTGG	CDK8	ENSG00000132964	-0.9623490443073035	[99,133]	[10,14]	-5	dCas9-VP64	positive selection	2417473
26254522	26254545	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGGCCGGCGGGCGTAGAGCGG	CDK8	ENSG00000132964	-1.178946423490621	[243,19]	[15,7]	-6	dCas9-VP64	positive selection	2417474
26258495	26258518	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGTAGG	CDK8	ENSG00000132964	4.847110262494055	[32,12]	[264,23]	9	dCas9-VP64	positive selection	2428808
26403358	26403381	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAAAAATTAGCTGAGCATGGAGG	CDK8	ENSG00000132964	-0.9961217982401208	[173,262]	[18,28]	-6	dCas9-VP64	positive selection	2464463
26335918	26335941	13	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTTGTTGTTGTTGTTGTTAAG	CDK8	ENSG00000132964	-0.6691815338040683	[248,92]	[41,27]	-6	dCas9-VP64	positive selection	2496478
26254446	26254469	13	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGACATCCAGGGGGACGGCGGG	CDK8	ENSG00000132964	-0.09458447302597905	[27,17]	[10,2]	0	dCas9-VP64	positive selection	2512727
26254496	26254519	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCCGCATCAGTCGGGCTGG	CDK8	ENSG00000132964	-0.4115609352454729	[252,237]	[51,66]	-4	dCas9-VP64	positive selection	2512728
26254522	26254545	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGGCCGGCGGGCGTAGAGCGG	CDK8	ENSG00000132964	-0.254102684938882	[12,108]	[5,24]	-2	dCas9-VP64	positive selection	2512729
26258495	26258518	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGTAGG	CDK8	ENSG00000132964	0.8889753160498469	[90,141]	[86,53]	6	dCas9-VP64	positive selection	2524063
26403358	26403381	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAAAAATTAGCTGAGCATGGAGG	CDK8	ENSG00000132964	0.8516263673058089	[132,219]	[112,94]	5	dCas9-VP64	positive selection	2559718
26353794	26353817	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.1962816689864354	[4,4]	[4,3]	4	hSpCas9	positive selection	2978228
26349176	26349199	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.06526537238402297	[4,4]	[4,3]	1	hSpCas9	positive selection	2978229
26353794	26353817	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.5750378428611654	[4,4]	[4,4]	8	hSpCas9	positive selection	3046086
26349176	26349199	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.06497508538868127	[4,4]	[4,1]	1	hSpCas9	positive selection	3046087
26349160	26349183		+	24336571	A375	resistance to PLX after 7 days	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.2506244085838081	[33,33]	[38,41]	7	hSpCas9	positive selection	3104646
26254689	26254712		+	24336571	A375	resistance to PLX after 7 days	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.5927736072064241	[19,18]	[30,26]	9	hSpCas9	positive selection	3104647
26254695	26254718		-	24336571	A375	resistance to PLX after 7 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3259146081828135	[8,9]	[11,10]	8	hSpCas9	positive selection	3104648
26349160	26349183		+	24336571	A375	resistance to PLX after 14 days	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.576450589547381	[37,47]	[28,29]	5	hSpCas9	positive selection	3162439
26254689	26254712		+	24336571	A375	resistance to PLX after 14 days	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	1.5026665730755044	[20,19]	[29,24]	9	hSpCas9	positive selection	3162440
26254695	26254718		-	24336571	A375	resistance to PLX after 14 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.8984892503067887	[6,11]	[7,8]	7	hSpCas9	positive selection	3162441
26349160	26349183		+	24336571	A375	viability after 7 days	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.795694312037975	[20]	[33,33]	9	hSpCas9	negative selection	3220232
26254689	26254712		+	24336571	A375	viability after 7 days	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.7694044493017841	[11]	[19,18]	9	hSpCas9	negative selection	3220233
26254695	26254718		-	24336571	A375	viability after 7 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.27018355758694734	[11]	[8,9]	-4	hSpCas9	negative selection	3220234
26349160	26349183		+	24336571	A375	viability after 14 days	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	1.1343480824364027	[20]	[37,47]	9	hSpCas9	negative selection	3278025
26254689	26254712		+	24336571	A375	viability after 14 days	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.8696847262583173	[11]	[20,19]	9	hSpCas9	negative selection	3278026
26254695	26254718		-	24336571	A375	viability after 14 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.17623713344466033	[11]	[6,11]	-2	hSpCas9	negative selection	3278027
26254689	26254712	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.01879658508459023	[152,148]	[0,0]	0	hSpCas9	positive selection	3342439
26254695	26254718	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	2.4698873732799074	[374,453]	[0,28]	8	hSpCas9	positive selection	3342440
26353847	26353870	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.30815751439979105	[133,112]	[0,0]	1	hSpCas9	positive selection	3342441
26353840	26353863	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	-1.8194893856049958	[539,539]	[0,0]	-9	hSpCas9	positive selection	3361673
26349160	26349183	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.10022579317224871	[163,163]	[0,0]	0	hSpCas9	positive selection	3361674
26349118	26349141	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	-0.2264895658184215	[178,178]	[0,0]	-1	hSpCas9	positive selection	3361675
26353794	26353817	13	-	26780180	HT29	viability (Avana library 4 designs)	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	-0.822016089739568	[]	[]	-9	hSpCas9	negative selection	3414539
26349176	26349199	13	-	26780180	HT29	viability (Avana library 4 designs)	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.443093683532737	[]	[]	1	hSpCas9	negative selection	3414540
26254690	26254713	13	+	26780180	HT29	viability (Avana library 4 designs)	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.739754956199962	[]	[]	3	hSpCas9	negative selection	3414541
26254708	26254731	13	+	26780180	HT29	viability (Avana library 4 designs)	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	1.52914202881379	[]	[]	6	hSpCas9	negative selection	3414542
26254708	26254731	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	7.96095232017929	[]	[]	9	hSpCas9	negative selection	3491107
26254690	26254713	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.642337307101206	[]	[]	-1	hSpCas9	negative selection	3491108
26353794	26353817	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	6.55848632007453	[]	[]	9	hSpCas9	negative selection	3491109
26349176	26349199	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	2.80144697785745	[]	[]	4	hSpCas9	negative selection	3491110
26254708	26254731	13	+	26780180	A375	viability (Avana lentiGuide)	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-1.02339794227168	[]	[]	-2	hSpCas9	negative selection	3599766
26254690	26254713	13	+	26780180	A375	viability (Avana lentiGuide)	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-1.82792631285349	[]	[]	-3	hSpCas9	negative selection	3599767
26353794	26353817	13	-	26780180	A375	viability (Avana lentiGuide)	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	-4.63713132589437	[]	[]	-7	hSpCas9	negative selection	3599768
26349176	26349199	13	-	26780180	A375	viability (Avana lentiGuide)	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	-3.22055936687692	[]	[]	-5	hSpCas9	negative selection	3599769
26254708	26254731	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.57859439996542	[5]	[8,8]	9	hSpCas9	positive selection	3708425
26254690	26254713	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.20559552091802896	[5]	[6,5]	6	hSpCas9	positive selection	3708426
26353794	26353817	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.43022909280044647	[5]	[7,6]	9	hSpCas9	positive selection	3708427
26349176	26349199	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.4905858349077793	[4]	[7,6]	9	hSpCas9	positive selection	3708428
26254708	26254731	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.20610433497034808	[6]	[4,6]	5	hSpCas9	positive selection	3817032
26254690	26254713	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.21856842451938013	[5]	[5,4]	5	hSpCas9	positive selection	3817033
26353794	26353817	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.37096328908179943	[6]	[7,6]	9	hSpCas9	positive selection	3817034
26349176	26349199	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.5830980401371291	[5]	[7,7]	9	hSpCas9	positive selection	3817035
26349160	26349183	13	+	26780180	A375	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.543277163973206	[]	[]	1	hSpCas9	negative selection	3925213
26254689	26254712	13	+	26780180	A375	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.315945438159561	[]	[]	0	hSpCas9	negative selection	3925214
26353847	26353870	13	-	26780180	A375	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.19011488426218	[]	[]	6	hSpCas9	negative selection	3925215
26254695	26254718	13	-	26780180	A375	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.921922161277396	[]	[]	4	hSpCas9	negative selection	3925216
26349118	26349141	13	+	26780180	A375	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.667607428194156	[]	[]	2	hSpCas9	negative selection	3925217
26353840	26353863	13	+	26780180	A375	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.837425751066213	[]	[]	3	hSpCas9	negative selection	3925218
26349160	26349183	13	+	26780180	HT29	viability (GeCKOv2 library)	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.56919884590249	[]	[]	2	hSpCas9	negative selection	4033179
26254689	26254712	13	+	26780180	HT29	viability (GeCKOv2 library)	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.28539829216244	[]	[]	0	hSpCas9	negative selection	4033180
26353847	26353870	13	-	26780180	HT29	viability (GeCKOv2 library)	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.1054625266276	[]	[]	5	hSpCas9	negative selection	4033181
26254695	26254718	13	-	26780180	HT29	viability (GeCKOv2 library)	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.90990577527551	[]	[]	4	hSpCas9	negative selection	4033182
26349118	26349141	13	+	26780180	HT29	viability (GeCKOv2 library)	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.175006574402875	[]	[]	0	hSpCas9	negative selection	4033183
26353840	26353863	13	+	26780180	HT29	viability (GeCKOv2 library)	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.910236836901893	[]	[]	4	hSpCas9	negative selection	4033184
26349160	26349183	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	0.47032287633356085	[4]	[3,4]	8	hSpCas9	positive selection	4126675
26254689	26254712	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.5143941615312562	[3]	[3,4]	9	hSpCas9	positive selection	4126676
26254695	26254718	13	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.24093828325095584	[2]	[1,2]	6	hSpCas9	positive selection	4126677
26349160	26349183	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	1.4105826676258517	[4]	[5,4,4,5]	9	hSpCas9	positive selection	4190697
26254689	26254712	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	1.6062782224860628	[3]	[3,3,5,5]	9	hSpCas9	positive selection	4190698
26254695	26254718	13	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.2808696538369824	[1]	[4,2,1,0]	9	hSpCas9	positive selection	4190699
26254689	26254712	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.4339379184253021	[3]	[4,4]	8	hSpCas9	positive selection	4262494
26254695	26254718	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.4438384547081488	[4]	[4,4]	8	hSpCas9	positive selection	4262495
26353847	26353870	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.06569239509166132	[3]	[3,1]	1	hSpCas9	positive selection	4262496
26353840	26353863	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.4082888120690067	[4]	[4,4]	8	hSpCas9	positive selection	4326772
26349160	26349183	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.22828024765752622	[4]	[4,1]	-5	hSpCas9	positive selection	4326773
26349118	26349141	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3229556555471172	[3]	[3,2]	6	hSpCas9	positive selection	4326774
26349096	26349118	13	+	27760321	OCIAML3	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.33884704277794775	[62,41]	[42,61]	4	hSpCas9	negative selection	4388106
26349176	26349198	13	-	27760321	OCIAML3	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.7766596995433097	[377,338]	[385,601]	8	hSpCas9	negative selection	4388107
26353780	26353802	13	+	27760321	OCIAML3	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	-0.1904926052559098	[562,428]	[348,321]	-2	hSpCas9	negative selection	4388108
26353816	26353838	13	+	27760321	OCIAML3	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-2.650130067792686	[7,7]	[0,0]	-9	hSpCas9	negative selection	4388109
26353847	26353869	13	-	27760321	OCIAML3	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.09576963428748614	[570,488]	[461,414]	1	hSpCas9	negative selection	4388110
26349096	26349118	13	+	27760321	OCIAML2	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	1.116172456996344	[62,41]	[111,62]	9	hSpCas9	negative selection	4471569
26349176	26349198	13	-	27760321	OCIAML2	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.27206866239515815	[377,338]	[338,363]	3	hSpCas9	negative selection	4471570
26353780	26353802	13	+	27760321	OCIAML2	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	-0.2535490357203663	[562,428]	[361,296]	-3	hSpCas9	negative selection	4471571
26353816	26353838	13	+	27760321	OCIAML2	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	0.8619409803317186	[7,7]	[19,0]	9	hSpCas9	negative selection	4471572
26353847	26353869	13	-	27760321	OCIAML2	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.3564898364790731	[570,488]	[510,594]	5	hSpCas9	negative selection	4471573
26349096	26349118	13	+	27760321	MV411	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	-3.0948959836432532	[62,41]	[5,0]	-9	hSpCas9	negative selection	4555032
26349176	26349198	13	-	27760321	MV411	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.5063824806211432	[377,338]	[399,238]	3	hSpCas9	negative selection	4555033
26353780	26353802	13	+	27760321	MV411	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.090327889782749	[562,428]	[272,454]	0	hSpCas9	negative selection	4555034
26353816	26353838	13	+	27760321	MV411	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	3.6161379725931133	[7,7]	[0,160]	9	hSpCas9	negative selection	4555035
26353847	26353869	13	-	27760321	MV411	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-1.9379450936079814	[570,488]	[90,90]	-8	hSpCas9	negative selection	4555036
26349096	26349118	13	+	27760321	HL60	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	-0.6594733692175487	[62,41]	[19,33]	-6	hSpCas9	negative selection	4638495
26349176	26349198	13	-	27760321	HL60	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.7786380993182115	[377,338]	[494,508]	8	hSpCas9	negative selection	4638496
26353780	26353802	13	+	27760321	HL60	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	-0.0894330231050322	[562,428]	[322,435]	-1	hSpCas9	negative selection	4638497
26353816	26353838	13	+	27760321	HL60	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	3.0708505869279095	[7,7]	[24,86]	9	hSpCas9	negative selection	4638498
26353847	26353869	13	-	27760321	HL60	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.3654304479419198	[570,488]	[269,403]	-4	hSpCas9	negative selection	4638499
26349096	26349118	13	+	27760321	HT1080	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.734594626009935	[41,32]	[0,50]	4	hSpCas9	negative selection	4721958
26349176	26349198	13	-	27760321	HT1080	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.0487870432653552	[338,264]	[204,296]	5	hSpCas9	negative selection	4721959
26353780	26353802	13	+	27760321	HT1080	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	-0.27917834710954015	[428,334]	[133,115]	-1	hSpCas9	negative selection	4721960
26353816	26353838	13	+	27760321	HT1080	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-1.4759873735460216	[7,5]	[0,0]	-5	hSpCas9	negative selection	4721961
26353847	26353869	13	-	27760321	HT1080	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.549415145239845	[488,381]	[209,301]	3	hSpCas9	negative selection	4721962
26349096	26349118	13	+	27760321	HT29	viability after 7 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	-0.9212646056129778	[41,32]	[10,27,34]	-8	hSpCas9	negative selection	4805421
26349176	26349198	13	-	27760321	HT29	viability after 7 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.6742113221825774	[338,264]	[671,683,512]	8	hSpCas9	negative selection	4805422
26353780	26353802	13	+	27760321	HT29	viability after 7 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.6931463542132128	[428,334]	[1180,831,434]	9	hSpCas9	negative selection	4805423
26353816	26353838	13	+	27760321	HT29	viability after 7 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-0.5355940780539186	[7,5]	[0,15,0]	-7	hSpCas9	negative selection	4805424
26353847	26353869	13	-	27760321	HT29	viability after 7 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.10592409549554677	[488,381]	[774,594,465]	1	hSpCas9	negative selection	4805425
26349096	26349118	13	+	27760321	HT29	viability after 25 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.21591413038543283	[41,32]	[66,41,37]	2	hSpCas9	negative selection	4888884
26349176	26349198	13	-	27760321	HT29	viability after 25 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.0161581670438207	[338,264]	[736,567,795]	9	hSpCas9	negative selection	4888885
26353780	26353802	13	+	27760321	HT29	viability after 25 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.5385685795053217	[428,334]	[473,695,753]	6	hSpCas9	negative selection	4888886
26353816	26353838	13	+	27760321	HT29	viability after 25 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-1.3873365272062488	[7,5]	[1,5,0]	-7	hSpCas9	negative selection	4888887
26353847	26353869	13	-	27760321	HT29	viability after 25 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.3959448429096444	[488,381]	[590,762,608]	4	hSpCas9	negative selection	4888888
26349096	26349118	13	+	27760321	HT29	viability after 22 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.335601102230497	[41,32]	[92,30,38]	3	hSpCas9	negative selection	4972347
26349176	26349198	13	-	27760321	HT29	viability after 22 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.8618696634614187	[338,264]	[750,568,579]	8	hSpCas9	negative selection	4972348
26353780	26353802	13	+	27760321	HT29	viability after 22 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.4930850929909958	[428,334]	[329,769,773]	5	hSpCas9	negative selection	4972349
26353816	26353838	13	+	27760321	HT29	viability after 22 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-2.017189330037451	[7,5]	[0,3,0]	-8	hSpCas9	negative selection	4972350
26353847	26353869	13	-	27760321	HT29	viability after 22 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.39933599517197904	[488,381]	[754,535,698]	4	hSpCas9	negative selection	4972351
26349096	26349118	13	+	27760321	HT29	viability after 19 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.9153268583836915	[41,32]	[55,180,5]	8	hSpCas9	negative selection	5055810
26349176	26349198	13	-	27760321	HT29	viability after 19 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.2673466231095016	[338,264]	[1056,1096,380]	9	hSpCas9	negative selection	5055811
26353780	26353802	13	+	27760321	HT29	viability after 19 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.6978010837043218	[428,334]	[896,613,636]	7	hSpCas9	negative selection	5055812
26353816	26353838	13	+	27760321	HT29	viability after 19 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-2.9971482178285918	[7,5]	[0,0,0]	-8	hSpCas9	negative selection	5055813
26353847	26353869	13	-	27760321	HT29	viability after 19 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.09052557014805551	[488,381]	[545,747,306]	0	hSpCas9	negative selection	5055814
26349096	26349118	13	+	27760321	HT29	viability after 16 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	1.465214320239158	[41,32]	[58,87,195]	9	hSpCas9	negative selection	5139273
26349176	26349198	13	-	27760321	HT29	viability after 16 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.546473483039977	[338,264]	[618,391,483]	6	hSpCas9	negative selection	5139274
26353780	26353802	13	+	27760321	HT29	viability after 16 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.43712471803542474	[428,334]	[483,575,666]	5	hSpCas9	negative selection	5139275
26353816	26353838	13	+	27760321	HT29	viability after 16 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-1.8050688131179031	[7,5]	[4,0,0]	-8	hSpCas9	negative selection	5139276
26353847	26353869	13	-	27760321	HT29	viability after 16 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.07837236572231432	[488,381]	[476,467,595]	0	hSpCas9	negative selection	5139277
26349096	26349118	13	+	27760321	HT29	viability after 13 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	0.06706068787559971	[41,32]	[43,33,57]	0	hSpCas9	negative selection	5222736
26349176	26349198	13	-	27760321	HT29	viability after 13 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.5997586679410861	[338,264]	[461,547,579]	7	hSpCas9	negative selection	5222737
26353780	26353802	13	+	27760321	HT29	viability after 13 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.8187767106877422	[428,334]	[806,756,780]	9	hSpCas9	negative selection	5222738
26353816	26353838	13	+	27760321	HT29	viability after 13 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-1.619992245914931	[7,5]	[5,0,0]	-8	hSpCas9	negative selection	5222739
26353847	26353869	13	-	27760321	HT29	viability after 13 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.09156308448828115	[488,381]	[520,435,650]	1	hSpCas9	negative selection	5222740
26349096	26349118	13	+	27760321	HT29	viability after 10 days	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	-1.0999203965129483	[41,32]	[18,11,33]	-8	hSpCas9	negative selection	5306199
26349176	26349198	13	-	27760321	HT29	viability after 10 days	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.7086898085280329	[338,264]	[755,717,382]	8	hSpCas9	negative selection	5306200
26353780	26353802	13	+	27760321	HT29	viability after 10 days	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.6296456352016031	[428,334]	[722,749,740]	8	hSpCas9	negative selection	5306201
26353816	26353838	13	+	27760321	HT29	viability after 10 days	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	-0.8995593572498217	[7,5]	[11,0,0]	-7	hSpCas9	negative selection	5306202
26353847	26353869	13	-	27760321	HT29	viability after 10 days	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.21198329418963308	[488,381]	[251,499,652]	-3	hSpCas9	negative selection	5306203
26349096	26349118	13	+	27760321	MOLM13	viability	AACGTCATTTCTCTTCAAAAGG	CDK8	ENSG00000132964	1.0618224697394467	[62,41]	[53,66]	7	hSpCas9	negative selection	5389662
26349176	26349198	13	-	27760321	MOLM13	viability	AGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.314630990251545	[377,338]	[656,370]	8	hSpCas9	negative selection	5389663
26353780	26353802	13	+	27760321	MOLM13	viability	AGCCAGTTCAGTTACCTCGGGG	CDK8	ENSG00000132964	0.7847937629004791	[562,428]	[143,762]	5	hSpCas9	negative selection	5389664
26353816	26353838	13	+	27760321	MOLM13	viability	TATTATATCAGATCCTAGATGG	CDK8	ENSG00000132964	2.8114681507957835	[7,7]	[0,57]	9	hSpCas9	negative selection	5389665
26353847	26353869	13	-	27760321	MOLM13	viability	CAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.3843807761054772	[570,488]	[155,289]	-3	hSpCas9	negative selection	5389666
26254295	26254318	13	+	27661255	K562	viability	GAACGCGCGGCCGGAGAGAGCGG	CDK8	ENSG00000132964	-0.2479807116844832	[926,676]	[616,478]	-6	dCas9-KRAB	negative selection	5469939
26254536	26254559	13	+	27661255	K562	viability	GTAGAGCGGGCGGGTTCCCGGGG	CDK8	ENSG00000132964	-0.04908455972237882	[659,718]	[537,525]	-2	dCas9-KRAB	negative selection	5469940
26254117	26254140	13	-	27661255	K562	viability	GGTACCTCCTCAAAGAGAGGAGG	CDK8	ENSG00000132964	-0.009913176341186936	[963,1075]	[873,750]	0	dCas9-KRAB	negative selection	5469941
26254138	26254161	13	-	27661255	K562	viability	GGGCAGAGCCGCACAACAGCCGG	CDK8	ENSG00000132964	-0.3655037526996828	[1130,1005]	[732,604]	-7	dCas9-KRAB	negative selection	5469942
26254379	26254402	13	-	27661255	K562	viability	GAAGGAGAGCCGAGGGACGAGGG	CDK8	ENSG00000132964	-0.3149964089951078	[784,846]	[573,479]	-7	dCas9-KRAB	negative selection	5469943
26254689	26254712	13	+	27260156	BXPC3	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.10137345704884881	[959]	[831,867,859,1225]	-2	hSpCas9	negative selection	5534954
26254695	26254718	13	-	27260156	BXPC3	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.11830493494415384	[1357]	[1252,1427,1723,1825]	2	hSpCas9	negative selection	5534955
26353847	26353870	13	-	27260156	BXPC3	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.14385582881534142	[531]	[342,490,529,687]	-3	hSpCas9	negative selection	5534956
26353840	26353863	13	+	27260156	BXPC3	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.1275604656691096	[1370]	[1415,1718,1409,1732]	3	hSpCas9	negative selection	5599232
26349160	26349183	13	+	27260156	BXPC3	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.449093127724947	[1521]	[1100,1132,1225,1209]	-7	hSpCas9	negative selection	5599233
26349118	26349141	13	+	27260156	BXPC3	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.18579909536711375	[558]	[587,608,788,684]	4	hSpCas9	negative selection	5599234
26254689	26254712	13	+	27260156	A673	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.011566116536512405	[959]	[1045,1153,1164,1197]	0	hSpCas9	negative selection	5656205
26254695	26254718	13	-	27260156	A673	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.24916376808538265	[1357]	[2062,1632,1954,2129]	6	hSpCas9	negative selection	5656206
26353847	26353870	13	-	27260156	A673	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.058986821567720726	[531]	[655,552,589,661]	-1	hSpCas9	negative selection	5656207
26353840	26353863	13	+	27260156	A673	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.09053691026849497	[1370]	[1920,1535,1664,1920]	2	hSpCas9	negative selection	5720483
26349160	26349183	13	+	27260156	A673	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.37710558638849845	[1521]	[1369,1364,1215,1688]	-7	hSpCas9	negative selection	5720484
26349118	26349141	13	+	27260156	A673	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.33509173634227807	[558]	[984,766,797,853]	7	hSpCas9	negative selection	5720485
26254689	26254712	13	+	27260156	A375	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.17743121996823885	[959]	[1049,2053,1349,779]	2	hSpCas9	negative selection	5777456
26254695	26254718	13	-	27260156	A375	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.21435210217231204	[1357]	[1752,2396,1953,1381]	3	hSpCas9	negative selection	5777457
26353847	26353870	13	-	27260156	A375	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.030830219398707642	[531]	[607,647,662,620]	0	hSpCas9	negative selection	5777458
26353840	26353863	13	+	27260156	A375	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.39940835894600313	[1370]	[1887,2883,2088,1730]	6	hSpCas9	negative selection	5841734
26349160	26349183	13	+	27260156	A375	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.5411670204204309	[1521]	[1067,1490,1283,1090]	-6	hSpCas9	negative selection	5841735
26349118	26349141	13	+	27260156	A375	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.28253789932733564	[558]	[757,1118,792,574]	4	hSpCas9	negative selection	5841736
26254689	26254712	13	+	27260156	COLO741	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.11322640546448381	[959]	[1339,1264,1369]	2	hSpCas9	negative selection	5898707
26254695	26254718	13	-	27260156	COLO741	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.21346046613029745	[1357]	[2361,1993,1725]	4	hSpCas9	negative selection	5898708
26353847	26353870	13	-	27260156	COLO741	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.24285719782643156	[531]	[681,1246,495]	5	hSpCas9	negative selection	5898709
26353840	26353863	13	+	27260156	COLO741	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.07387279482630404	[1370]	[1993,1818,1734]	1	hSpCas9	negative selection	5962985
26349160	26349183	13	+	27260156	COLO741	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.38462159870986556	[1521]	[1350,1488,1604]	-7	hSpCas9	negative selection	5962986
26349118	26349141	13	+	27260156	COLO741	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.41037370641828863	[558]	[1136,800,924]	8	hSpCas9	negative selection	5962987
26254689	26254712	13	+	27260156	CAL120	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.2827131733346073	[959]	[1891,1354,1182]	4	hSpCas9	negative selection	6019958
26254695	26254718	13	-	27260156	CAL120	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.5699362389043521	[1357]	[3636,2476,1596]	8	hSpCas9	negative selection	6019959
26353847	26353870	13	-	27260156	CAL120	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.14740859940035467	[531]	[1058,712,480]	2	hSpCas9	negative selection	6019960
26353840	26353863	13	+	27260156	CAL120	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2709015313063894	[1370]	[2091,2108,1979]	4	hSpCas9	negative selection	6084236
26349160	26349183	13	+	27260156	CAL120	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.20893683546855013	[1521]	[1748,1390,1788]	-3	hSpCas9	negative selection	6084237
26349118	26349141	13	+	27260156	CAL120	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.038124977656867565	[558]	[637,1004,491]	0	hSpCas9	negative selection	6084238
26254689	26254712	13	+	27260156	CADOES1	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.21814468906112006	[959]	[1137,1035,945,1033]	3	hSpCas9	negative selection	6141209
26254695	26254718	13	-	27260156	CADOES1	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.42229847675962495	[1357]	[1973,1694,1571,1521]	7	hSpCas9	negative selection	6141210
26353847	26353870	13	-	27260156	CADOES1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.09229211998442743	[531]	[363,605,624,514]	1	hSpCas9	negative selection	6141211
26353840	26353863	13	+	27260156	CADOES1	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.4011592073543968	[1370]	[1889,1607,1573,1661]	6	hSpCas9	negative selection	6205487
26349160	26349183	13	+	27260156	CADOES1	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.2530486323685326	[1521]	[1225,1113,1146,1266]	-4	hSpCas9	negative selection	6205488
26349118	26349141	13	+	27260156	CADOES1	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.8368585756916422	[558]	[812,846,1089,965]	9	hSpCas9	negative selection	6205489
26254689	26254712	13	+	27260156	EWS502	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.29935964118943503	[959]	[1038,1127,1491,1384]	5	hSpCas9	negative selection	6262460
26254695	26254718	13	-	27260156	EWS502	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3241650034676691	[1357]	[1758,1671,1747,2043]	5	hSpCas9	negative selection	6262461
26353847	26353870	13	-	27260156	EWS502	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.2749054679794155	[531]	[539,583,593,1052]	5	hSpCas9	negative selection	6262462
26353840	26353863	13	+	27260156	EWS502	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2233517620875365	[1370]	[1631,1407,1646,2137]	4	hSpCas9	negative selection	6326738
26349160	26349183	13	+	27260156	EWS502	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.10378094514131564	[1521]	[1230,1279,1645,1910]	-2	hSpCas9	negative selection	6326739
26349118	26349141	13	+	27260156	EWS502	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.49397443253652085	[558]	[979,759,727,848]	8	hSpCas9	negative selection	6326740
26254689	26254712	13	+	27260156	EW8	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.11819315247419648	[959]	[768,935,576,613]	-2	hSpCas9	negative selection	6383711
26254695	26254718	13	-	27260156	EW8	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3351937934560474	[1357]	[1444,1696,1149,1305]	6	hSpCas9	negative selection	6383712
26353847	26353870	13	-	27260156	EW8	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.11285269092016614	[531]	[398,599,423,440]	2	hSpCas9	negative selection	6383713
26353840	26353863	13	+	27260156	EW8	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.23609086821390513	[1370]	[1643,987,1110,1555]	4	hSpCas9	negative selection	6447989
26349160	26349183	13	+	27260156	EW8	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.44838532776813733	[1521]	[868,1135,729,904]	-7	hSpCas9	negative selection	6447990
26349118	26349141	13	+	27260156	EW8	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.1284159598004685	[558]	[661,447,445,449]	2	hSpCas9	negative selection	6447991
26254689	26254712	13	+	27260156	CORL105	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.31809365649921695	[959]	[1421,1134,1639,1449]	6	hSpCas9	negative selection	6504962
26254695	26254718	13	-	27260156	CORL105	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3505697464862969	[1357]	[2049,1784,2456,1888]	6	hSpCas9	negative selection	6504963
26353847	26353870	13	-	27260156	CORL105	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.2786760289603796	[531]	[742,667,863,764]	5	hSpCas9	negative selection	6504964
26353840	26353863	13	+	27260156	CORL105	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2441518289930953	[1370]	[1860,1858,2242,1693]	4	hSpCas9	negative selection	6569240
26349160	26349183	13	+	27260156	CORL105	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.29653028709871454	[1521]	[1406,1250,1682,1499]	-5	hSpCas9	negative selection	6569241
26349118	26349141	13	+	27260156	CORL105	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3769728877905635	[558]	[942,749,923,798]	7	hSpCas9	negative selection	6569242
26254689	26254712	13	+	27260156	HS294T	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.5837483758060962	[959]	[708,519,472,497]	7	hSpCas9	negative selection	6626213
26254695	26254718	13	-	27260156	HS294T	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.2787863557270216	[1357]	[501,700,670,691]	4	hSpCas9	negative selection	6626214
26353847	26353870	13	-	27260156	HS294T	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.5465671793582281	[531]	[321,215,265,416]	7	hSpCas9	negative selection	6626215
26353840	26353863	13	+	27260156	HS294T	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.5938783750594907	[1370]	[786,984,692,712]	7	hSpCas9	negative selection	6690491
26349160	26349183	13	+	27260156	HS294T	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.11966630615638163	[1521]	[371,599,741,449]	-2	hSpCas9	negative selection	6690492
26349118	26349141	13	+	27260156	HS294T	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	-0.00492739370674572	[558]	[196,203,186,286]	0	hSpCas9	negative selection	6690493
26254689	26254712	13	+	27260156	HCC44	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.02087220914987209	[959]	[923,959,1527,1063]	0	hSpCas9	negative selection	6747464
26254695	26254718	13	-	27260156	HCC44	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.29613237693007277	[1357]	[2269,1288,2513,1689]	5	hSpCas9	negative selection	6747465
26353847	26353870	13	-	27260156	HCC44	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.048184358733288246	[531]	[943,441,659,502]	0	hSpCas9	negative selection	6747466
26353840	26353863	13	+	27260156	HCC44	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2227950257049951	[1370]	[1981,1140,2174,2089]	3	hSpCas9	negative selection	6811742
26349160	26349183	13	+	27260156	HCC44	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.10644657639115196	[1521]	[1753,1282,1733,1690]	-2	hSpCas9	negative selection	6811743
26349118	26349141	13	+	27260156	HCC44	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.22615369113264444	[558]	[906,376,775,957]	3	hSpCas9	negative selection	6811744
26254689	26254712	13	+	27260156	G402	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.23047352418321088	[959]	[969,1137,698,1177]	-3	hSpCas9	negative selection	6868715
26254695	26254718	13	-	27260156	G402	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.25098601350778305	[1357]	[2435,1756,1589,2142]	3	hSpCas9	negative selection	6868716
26353847	26353870	13	-	27260156	G402	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.5523916389428227	[531]	[443,654,421,268]	-6	hSpCas9	negative selection	6868717
26353840	26353863	13	+	27260156	G402	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.5514991982581487	[1370]	[2004,1763,3128,2778]	6	hSpCas9	negative selection	6932993
26349160	26349183	13	+	27260156	G402	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.6665057935236012	[1521]	[1404,1332,893,1090]	-7	hSpCas9	negative selection	6932994
26349118	26349141	13	+	27260156	G402	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.6848648974054966	[558]	[1266,1058,977,1099]	8	hSpCas9	negative selection	6932995
26254689	26254712	13	+	27260156	L33	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.13042341131097035	[959]	[982,407,566,626]	-3	hSpCas9	negative selection	6989966
26254695	26254718	13	-	27260156	L33	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.12036067862832422	[1357]	[1431,640,892,1487]	2	hSpCas9	negative selection	6989967
26353847	26353870	13	-	27260156	L33	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.18128134107589777	[531]	[566,193,249,435]	-4	hSpCas9	negative selection	6989968
26353840	26353863	13	+	27260156	L33	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.09596598806356083	[1370]	[1304,611,997,1478]	2	hSpCas9	negative selection	7054244
26349160	26349183	13	+	27260156	L33	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.7502229160458085	[1521]	[946,293,642,930]	-9	hSpCas9	negative selection	7054245
26349118	26349141	13	+	27260156	L33	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	-0.23790495798892827	[558]	[341,196,336,539]	-5	hSpCas9	negative selection	7054246
26254689	26254712	13	+	27260156	K562	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.21167980668157083	[959]	[741,748,508,918]	-3	hSpCas9	negative selection	7111217
26254695	26254718	13	-	27260156	K562	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.012636980598229597	[1357]	[1377,1534,1147,867]	0	hSpCas9	negative selection	7111218
26353847	26353870	13	-	27260156	K562	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.8381107350383488	[531]	[163,188,245,424]	-7	hSpCas9	negative selection	7111219
26353840	26353863	13	+	27260156	K562	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.23348927295937383	[1370]	[1413,1267,1445,1561]	3	hSpCas9	negative selection	7175495
26349160	26349183	13	+	27260156	K562	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-1.4066768981498559	[1521]	[663,697,439,282]	-9	hSpCas9	negative selection	7175496
26349118	26349141	13	+	27260156	K562	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.10859260795384701	[558]	[680,532,503,441]	1	hSpCas9	negative selection	7175497
26254689	26254712	13	+	27260156	HT29	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.2773030774875733	[959]	[1546,1399,1286,1420]	5	hSpCas9	negative selection	7232468
26254695	26254718	13	-	27260156	HT29	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.4025320500387708	[1357]	[2125,2371,2157,2080]	7	hSpCas9	negative selection	7232469
26353847	26353870	13	-	27260156	HT29	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.14669305744500966	[531]	[661,550,577,548]	-3	hSpCas9	negative selection	7232470
26353840	26353863	13	+	27260156	HT29	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.3419838900717722	[1370]	[2223,2250,2183,1830]	6	hSpCas9	negative selection	7296746
26349160	26349183	13	+	27260156	HT29	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.35730907864938843	[1521]	[1721,1993,1158,1013]	-6	hSpCas9	negative selection	7296747
26349118	26349141	13	+	27260156	HT29	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.4713499697697532	[558]	[920,960,1156,746]	8	hSpCas9	negative selection	7296748
26254689	26254712	13	+	27260156	MHHES1	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.3191487380485536	[959]	[1376,1423,1222,1349]	6	hSpCas9	negative selection	7353719
26254695	26254718	13	-	27260156	MHHES1	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3322005444760865	[1357]	[2010,2318,1660,1754]	6	hSpCas9	negative selection	7353720
26353847	26353870	13	-	27260156	MHHES1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.030817253523033133	[531]	[879,643,465,421]	0	hSpCas9	negative selection	7353721
26353840	26353863	13	+	27260156	MHHES1	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.3104705794737306	[1370]	[2262,2194,1686,1610]	5	hSpCas9	negative selection	7417997
26349160	26349183	13	+	27260156	MHHES1	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.23328562463695968	[1521]	[2156,1526,1210,1082]	-4	hSpCas9	negative selection	7417998
26349118	26349141	13	+	27260156	MHHES1	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.21967624820318898	[558]	[780,834,669,661]	4	hSpCas9	negative selection	7417999
26254689	26254712	13	+	27260156	MEWO	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.17949777071156636	[959]	[1134,1018,919]	4	hSpCas9	negative selection	7474970
26254695	26254718	13	-	27260156	MEWO	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.1455573622305637	[1357]	[1491,1316,1423]	3	hSpCas9	negative selection	7474971
26353847	26353870	13	-	27260156	MEWO	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.07416560590473796	[531]	[553,465,413]	-2	hSpCas9	negative selection	7474972
26353840	26353863	13	+	27260156	MEWO	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.1090308818452006	[1370]	[1768,1270,1184]	2	hSpCas9	negative selection	7539248
26349160	26349183	13	+	27260156	MEWO	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.07649693875305652	[1521]	[1674,1095,1343]	-2	hSpCas9	negative selection	7539249
26349118	26349141	13	+	27260156	MEWO	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3973554974092519	[558]	[800,691,594]	8	hSpCas9	negative selection	7539250
26254689	26254712	13	+	27260156	LNCAPCLONEFGC	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.26944794063225697	[959]	[1088,828,1379,956]	4	hSpCas9	negative selection	7596221
26254695	26254718	13	-	27260156	LNCAPCLONEFGC	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.5051683389190971	[1357]	[1727,1394,1771,2114]	7	hSpCas9	negative selection	7596222
26353847	26353870	13	-	27260156	LNCAPCLONEFGC	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.281387982626702	[531]	[583,557,657,554]	4	hSpCas9	negative selection	7596223
26353840	26353863	13	+	27260156	LNCAPCLONEFGC	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.3916827205029003	[1370]	[1650,1710,1606,1537]	6	hSpCas9	negative selection	7660499
26349160	26349183	13	+	27260156	LNCAPCLONEFGC	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.2467113314816871	[1521]	[1139,911,1389,1255]	-4	hSpCas9	negative selection	7660500
26349118	26349141	13	+	27260156	LNCAPCLONEFGC	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.38477312140016096	[558]	[603,721,571,729]	6	hSpCas9	negative selection	7660501
26254689	26254712	13	+	27260156	PANC0327	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.686482563363627	[959]	[592,494,496,543]	-7	hSpCas9	negative selection	7717472
26254695	26254718	13	-	27260156	PANC0327	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	-0.009589555871091004	[1357]	[1636,956,1125,1139]	0	hSpCas9	negative selection	7717473
26353847	26353870	13	-	27260156	PANC0327	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-1.2151548158983352	[531]	[187,193,164,266]	-9	hSpCas9	negative selection	7717474
26353840	26353863	13	+	27260156	PANC0327	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2680148224604708	[1370]	[1828,1525,1102,1428]	4	hSpCas9	negative selection	7781750
26349160	26349183	13	+	27260156	PANC0327	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-1.1922648267367058	[1521]	[680,714,589,371]	-9	hSpCas9	negative selection	7781751
26349118	26349141	13	+	27260156	PANC0327	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.07832398727116574	[558]	[541,548,437,565]	1	hSpCas9	negative selection	7781752
26254689	26254712	13	+	27260156	NCIH2009	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.17265126790594687	[959]	[1590,1480,1476]	2	hSpCas9	negative selection	7838723
26254695	26254718	13	-	27260156	NCIH2009	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.5074601331273207	[1357]	[3038,2776,2336]	7	hSpCas9	negative selection	7838724
26353847	26353870	13	-	27260156	NCIH2009	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.11405346118321119	[531]	[1004,581,536]	-1	hSpCas9	negative selection	7838725
26353840	26353863	13	+	27260156	NCIH2009	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.574431154411339	[1370]	[3515,2708,2460]	7	hSpCas9	negative selection	7903001
26349160	26349183	13	+	27260156	NCIH2009	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.38223405137094035	[1521]	[2112,1465,1410]	-5	hSpCas9	negative selection	7903002
26349118	26349141	13	+	27260156	NCIH2009	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3526960461703862	[558]	[768,1057,1116]	5	hSpCas9	negative selection	7903003
26254689	26254712	13	+	27260156	NCIH1373	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.7709157013620962	[959]	[2223,1256,2006,518]	7	hSpCas9	negative selection	7959974
26254695	26254718	13	-	27260156	NCIH1373	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.609127421696356	[1357]	[3103,2428,2176,429]	6	hSpCas9	negative selection	7959975
26353847	26353870	13	-	27260156	NCIH1373	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.3186837898685887	[531]	[837,1004,683,107]	3	hSpCas9	negative selection	7959976
26353840	26353863	13	+	27260156	NCIH1373	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.6562642610621281	[1370]	[2780,1620,2951,644]	6	hSpCas9	negative selection	8024252
26349160	26349183	13	+	27260156	NCIH1373	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.5573422724601409	[1521]	[1624,1168,724,313]	-5	hSpCas9	negative selection	8024253
26349118	26349141	13	+	27260156	NCIH1373	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.5228995528211624	[558]	[1055,558,785,336]	5	hSpCas9	negative selection	8024254
26254689	26254712	13	+	27260156	PATU8902	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.48564841396787606	[959]	[1634,2238,1756,1876]	5	hSpCas9	negative selection	8081225
26254695	26254718	13	-	27260156	PATU8902	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.7073144185366087	[1357]	[2685,2964,3483,3094]	7	hSpCas9	negative selection	8081226
26353847	26353870	13	-	27260156	PATU8902	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.025281098702118393	[531]	[394,1014,664,869]	0	hSpCas9	negative selection	8081227
26353840	26353863	13	+	27260156	PATU8902	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.6562669953967268	[1370]	[2922,3762,2571,2852]	7	hSpCas9	negative selection	8145503
26349160	26349183	13	+	27260156	PATU8902	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.5015132321286966	[1521]	[1344,1252,1266,2264]	-5	hSpCas9	negative selection	8145504
26349118	26349141	13	+	27260156	PATU8902	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.6621324074198589	[558]	[1334,1117,1064,1469]	7	hSpCas9	negative selection	8145505
26254689	26254712	13	+	27260156	PANC1	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.5901629287759169	[959]	[1470,1431,1425,735]	8	hSpCas9	negative selection	8202476
26254695	26254718	13	-	27260156	PANC1	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.35562745379406113	[1357]	[1512,1509,1753,1218]	6	hSpCas9	negative selection	8202477
26353847	26353870	13	-	27260156	PANC1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.23640681179181272	[531]	[476,351,317,387]	-4	hSpCas9	negative selection	8202478
26353840	26353863	13	+	27260156	PANC1	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.2735273593056018	[1370]	[1411,1749,1554,1078]	4	hSpCas9	negative selection	8266754
26349160	26349183	13	+	27260156	PANC1	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.10163166675547264	[1521]	[940,1700,1254,1083]	-2	hSpCas9	negative selection	8266755
26349118	26349141	13	+	27260156	PANC1	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.2965133964258252	[558]	[551,724,491,604]	5	hSpCas9	negative selection	8266756
26254689	26254712	13	+	27260156	PANC0813	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.1279281160827761	[959]	[1505,1310,978,1158]	2	hSpCas9	negative selection	8323727
26254695	26254718	13	-	27260156	PANC0813	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3359703554984257	[1357]	[1965,1995,2218,1873]	5	hSpCas9	negative selection	8323728
26353847	26353870	13	-	27260156	PANC0813	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.027500589149866028	[531]	[537,654,662,589]	0	hSpCas9	negative selection	8323729
26353840	26353863	13	+	27260156	PANC0813	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.4133047366972902	[1370]	[2192,2143,2314,1939]	6	hSpCas9	negative selection	8388005
26349160	26349183	13	+	27260156	PANC0813	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.6085116972371953	[1521]	[1316,1043,1223,1119]	-7	hSpCas9	negative selection	8388006
26349118	26349141	13	+	27260156	PANC0813	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	-0.12323195761584729	[558]	[678,586,629,525]	-2	hSpCas9	negative selection	8388007
26254689	26254712	13	+	27260156	RDES	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.049099924737256107	[959]	[898,880,1267,1282]	-1	hSpCas9	negative selection	8444978
26254695	26254718	13	-	27260156	RDES	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.46900993717568173	[1357]	[1742,2260,2102,2621]	7	hSpCas9	negative selection	8444979
26353847	26353870	13	-	27260156	RDES	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.053892992255829206	[531]	[427,493,726,768]	-1	hSpCas9	negative selection	8444980
26353840	26353863	13	+	27260156	RDES	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.383165922425462	[1370]	[1599,1970,2482,2264]	6	hSpCas9	negative selection	8509256
26349160	26349183	13	+	27260156	RDES	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.33077202298818387	[1521]	[1235,1210,1370,1820]	-5	hSpCas9	negative selection	8509257
26349118	26349141	13	+	27260156	RDES	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.28037993178481	[558]	[693,639,843,986]	4	hSpCas9	negative selection	8509258
26254689	26254712	13	+	27260156	PC3	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.10045147329268911	[959]	[852,738,2019,835]	2	hSpCas9	negative selection	8566229
26254695	26254718	13	-	27260156	PC3	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.10255234953060999	[1357]	[808,1592,2311,1584]	2	hSpCas9	negative selection	8566230
26353847	26353870	13	-	27260156	PC3	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.03305956360421172	[531]	[335,576,836,571]	0	hSpCas9	negative selection	8566231
26353840	26353863	13	+	27260156	PC3	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.03372285300579847	[1370]	[902,1376,2428,1364]	0	hSpCas9	negative selection	8630507
26349160	26349183	13	+	27260156	PC3	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.38890140672662454	[1521]	[803,1067,1905,1185]	-7	hSpCas9	negative selection	8630508
26349118	26349141	13	+	27260156	PC3	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3598321020347438	[558]	[376,613,1136,1003]	7	hSpCas9	negative selection	8630509
26254689	26254712	13	+	27260156	PATU8988T	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.05954388720654058	[959]	[735,1073,1351,686]	1	hSpCas9	negative selection	8687480
26254695	26254718	13	-	27260156	PATU8988T	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.022385969935996064	[1357]	[1174,1317,1276,1579]	0	hSpCas9	negative selection	8687481
26353847	26353870	13	-	27260156	PATU8988T	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.17077545320680543	[531]	[751,455,555,535]	3	hSpCas9	negative selection	8687482
26353840	26353863	13	+	27260156	PATU8988T	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	-0.016462039633358794	[1370]	[1536,1347,1109,1244]	0	hSpCas9	negative selection	8751758
26349160	26349183	13	+	27260156	PATU8988T	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.37678852466568946	[1521]	[898,1340,1306,988]	-6	hSpCas9	negative selection	8751759
26349118	26349141	13	+	27260156	PATU8988T	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.28394521236519954	[558]	[670,571,638,747]	5	hSpCas9	negative selection	8751760
26254689	26254712	13	+	27260156	T47D	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	-0.12543874712452252	[959]	[1113,933,1031,1028]	-3	hSpCas9	negative selection	8808731
26254695	26254718	13	-	27260156	T47D	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.2011956127236123	[1357]	[2069,1486,2025,1714]	4	hSpCas9	negative selection	8808732
26353847	26353870	13	-	27260156	T47D	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.3976135846019071	[531]	[502,417,414,553]	-7	hSpCas9	negative selection	8808733
26353840	26353863	13	+	27260156	T47D	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.18561196724201223	[1370]	[1938,1783,1649,1900]	4	hSpCas9	negative selection	8873009
26349160	26349183	13	+	27260156	T47D	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.570853190938619	[1521]	[1154,1205,1252,1156]	-8	hSpCas9	negative selection	8873010
26349118	26349141	13	+	27260156	T47D	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.1667441652442968	[558]	[713,681,696,838]	3	hSpCas9	negative selection	8873011
26254689	26254712	13	+	27260156	SU8686	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.06084667952593459	[959]	[843,779,1246,1173]	1	hSpCas9	negative selection	8929982
26254695	26254718	13	-	27260156	SU8686	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.32621376121522494	[1357]	[1570,1469,1747,2052]	5	hSpCas9	negative selection	8929983
26353847	26353870	13	-	27260156	SU8686	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.1370988668865313	[531]	[394,369,619,572]	-2	hSpCas9	negative selection	8929984
26353840	26353863	13	+	27260156	SU8686	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.32522171891410845	[1370]	[1613,1541,1834,1869]	5	hSpCas9	negative selection	8994260
26349160	26349183	13	+	27260156	SU8686	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.6893872091828879	[1521]	[711,770,1191,1149]	-7	hSpCas9	negative selection	8994261
26349118	26349141	13	+	27260156	SU8686	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	-0.09660643615132711	[558]	[525,456,564,531]	-2	hSpCas9	negative selection	8994262
26254689	26254712	13	+	27260156	SKES1	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.16013944323764195	[959]	[1215,1209,944,950]	3	hSpCas9	negative selection	9051233
26254695	26254718	13	-	27260156	SKES1	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3532103757836387	[1357]	[1810,1880,1684,1574]	7	hSpCas9	negative selection	9051234
26353847	26353870	13	-	27260156	SKES1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.05979371982780912	[531]	[410,607,696,483]	1	hSpCas9	negative selection	9051235
26353840	26353863	13	+	27260156	SKES1	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.23884308986892933	[1370]	[1783,1860,1449,1421]	5	hSpCas9	negative selection	9115511
26349160	26349183	13	+	27260156	SKES1	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.2836167587447298	[1521]	[1339,1361,1127,1181]	-6	hSpCas9	negative selection	9115512
26349118	26349141	13	+	27260156	SKES1	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.28047246285841965	[558]	[572,944,456,739]	6	hSpCas9	negative selection	9115513
26254689	26254712	13	+	27260156	TOV112D	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.08121610812759306	[959]	[1041,1453,859,825]	1	hSpCas9	negative selection	9172484
26254695	26254718	13	-	27260156	TOV112D	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.3485040895671494	[1357]	[1291,2350,1466,1923]	6	hSpCas9	negative selection	9172485
26353847	26353870	13	-	27260156	TOV112D	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.2896252757625929	[531]	[522,498,351,392]	-5	hSpCas9	negative selection	9172486
26353840	26353863	13	+	27260156	TOV112D	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.34424969059178934	[1370]	[1822,1763,1700,1694]	6	hSpCas9	negative selection	9236762
26349160	26349183	13	+	27260156	TOV112D	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.10321309383959343	[1521]	[1492,1777,1308,1194]	-2	hSpCas9	negative selection	9236763
26349118	26349141	13	+	27260156	TOV112D	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.428593685263822	[558]	[967,752,743,570]	7	hSpCas9	negative selection	9236764
26254689	26254712	13	+	27260156	TC71	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.057684306458089196	[959]	[914,1114,972,1301]	1	hSpCas9	negative selection	9293735
26254695	26254718	13	-	27260156	TC71	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.024361763765671673	[1357]	[1374,1418,1661,1460]	0	hSpCas9	negative selection	9293736
26353847	26353870	13	-	27260156	TC71	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.3167608564701837	[531]	[321,528,525,454]	-7	hSpCas9	negative selection	9293737
26353840	26353863	13	+	27260156	TC71	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	-0.024496118204615724	[1370]	[1536,1317,1419,1506]	0	hSpCas9	negative selection	9358013
26349160	26349183	13	+	27260156	TC71	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.28468083317727455	[1521]	[1098,1450,1163,1674]	-6	hSpCas9	negative selection	9358014
26349118	26349141	13	+	27260156	TC71	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.3386910207541024	[558]	[745,731,814,734]	7	hSpCas9	negative selection	9358015
26254689	26254712	13	+	27260156	TC32	viability	CGAGGACCTGTTTGAATACGAGG	CDK8	ENSG00000132964	0.06535226387300064	[959]	[869,732,1263,999]	1	hSpCas9	negative selection	9414986
26254695	26254718	13	-	27260156	TC32	viability	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.2867258802332304	[1357]	[1560,1107,2042,1682]	5	hSpCas9	negative selection	9414987
26353847	26353870	13	-	27260156	TC32	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.1209408396388634	[531]	[372,239,678,666]	-2	hSpCas9	negative selection	9414988
26353840	26353863	13	+	27260156	TC32	viability	TTCACTACCTGCATGCTAACTGG	CDK8	ENSG00000132964	0.39201626865840633	[1370]	[1638,1016,2364,2044]	6	hSpCas9	negative selection	9479264
26349160	26349183	13	+	27260156	TC32	viability	ACTATGCTGAACATGACCTCTGG	CDK8	ENSG00000132964	-0.37854489031321803	[1521]	[1182,744,1392,1193]	-6	hSpCas9	negative selection	9479265
26349118	26349141	13	+	27260156	TC32	viability	TGTTTCTGTCTCATGCTGATAGG	CDK8	ENSG00000132964	0.6196282693248161	[558]	[552,795,961,937]	9	hSpCas9	negative selection	9479266
26254690	26254713	13	+	27869803	HPAFII	viability after 27 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.17360936998614807	[101]	[94,7,NaN]	-1	hSpCas9	negative selection	9549525
26254695	26254718	13	-	27869803	HPAFII	viability after 27 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.9481773589828171	[764]	[937,640,NaN]	7	hSpCas9	negative selection	9549526
26349176	26349199	13	-	27869803	HPAFII	viability after 27 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.2962455509200805	[438]	[778,389,NaN]	9	hSpCas9	negative selection	9549527
26385301	26385324	13	+	27869803	HPAFII	viability after 27 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.5327522433244978	[463]	[281,411,NaN]	4	hSpCas9	negative selection	9549528
26393455	26393478	13	+	27869803	HPAFII	viability after 27 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-1.0136147773412507	[117]	[45,17,NaN]	-6	hSpCas9	negative selection	9549529
26254690	26254713	13	+	27869803	HPAFII	viability after 15 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.6948016250255343	[101]	[264,122,NaN]	7	hSpCas9	negative selection	9631974
26254695	26254718	13	-	27869803	HPAFII	viability after 15 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.5409629141232464	[764]	[1633,923,NaN]	6	hSpCas9	negative selection	9631975
26349176	26349199	13	-	27869803	HPAFII	viability after 15 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.6836562245777597	[438]	[1120,531,NaN]	7	hSpCas9	negative selection	9631976
26385301	26385324	13	+	27869803	HPAFII	viability after 15 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.8844100089643725	[463]	[832,974,NaN]	8	hSpCas9	negative selection	9631977
26393455	26393478	13	+	27869803	HPAFII	viability after 15 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.02865487354430596	[117]	[256,49,NaN]	0	hSpCas9	negative selection	9631978
26254690	26254713	13	+	27869803	ASPC1	viability after 36 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.9726010189557073	[394]	[148,645,54]	8	hSpCas9	negative selection	9714423
26254695	26254718	13	-	27869803	ASPC1	viability after 36 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.093811855320074	[1453]	[841,1725,730]	8	hSpCas9	negative selection	9714424
26349176	26349199	13	-	27869803	ASPC1	viability after 36 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.8099603570426046	[1138]	[1545,1466,1214]	9	hSpCas9	negative selection	9714425
26385301	26385324	13	+	27869803	ASPC1	viability after 36 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	-0.019370921898806515	[1361]	[705,526,251]	0	hSpCas9	negative selection	9714426
26393455	26393478	13	+	27869803	ASPC1	viability after 36 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.04806817620721515	[311]	[370,11,9]	0	hSpCas9	negative selection	9714427
26254690	26254713	13	+	27869803	PATU8988S	viability after 35 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	1.0791787883225552	[263]	[289,158,NaN]	9	hSpCas9	negative selection	9796872
26254695	26254718	13	-	27869803	PATU8988S	viability after 35 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.49453704153644606	[1474]	[813,859,NaN]	5	hSpCas9	negative selection	9796873
26349176	26349199	13	-	27869803	PATU8988S	viability after 35 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.0232903574248957	[908]	[794,692,NaN]	9	hSpCas9	negative selection	9796874
26385301	26385324	13	+	27869803	PATU8988S	viability after 35 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.9060837642912035	[1083]	[875,759,NaN]	8	hSpCas9	negative selection	9796875
26393455	26393478	13	+	27869803	PATU8988S	viability after 35 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.34024144344641205	[202]	[104,101,NaN]	4	hSpCas9	negative selection	9796876
26254690	26254713	13	+	27869803	PATU8988S	viability after 31 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	1.0679017505237016	[263]	[232,204,NaN]	9	hSpCas9	negative selection	9879321
26254695	26254718	13	-	27869803	PATU8988S	viability after 31 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	0.539920731672306	[1474]	[767,965,NaN]	6	hSpCas9	negative selection	9879322
26349176	26349199	13	-	27869803	PATU8988S	viability after 31 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	0.9365567859721688	[908]	[537,891,NaN]	9	hSpCas9	negative selection	9879323
26385301	26385324	13	+	27869803	PATU8988S	viability after 31 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.6223155737750586	[1083]	[678,647,NaN]	7	hSpCas9	negative selection	9879324
26393455	26393478	13	+	27869803	PATU8988S	viability after 31 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.8887062902762642	[202]	[104,206,NaN]	8	hSpCas9	negative selection	9879325
26254690	26254713	13	+	27869803	HPAFII	viability after 35 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.06657816855714516	[101]	[77,16,NaN]	0	hSpCas9	negative selection	9961770
26254695	26254718	13	-	27869803	HPAFII	viability after 35 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.098413563350476	[764]	[951,690,NaN]	7	hSpCas9	negative selection	9961771
26349176	26349199	13	-	27869803	HPAFII	viability after 35 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.5535702026953215	[438]	[935,332,NaN]	9	hSpCas9	negative selection	9961772
26385301	26385324	13	+	27869803	HPAFII	viability after 35 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.6481343046949279	[463]	[250,499,NaN]	4	hSpCas9	negative selection	9961773
26393455	26393478	13	+	27869803	HPAFII	viability after 35 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	0.16229689379941137	[117]	[119,6,NaN]	1	hSpCas9	negative selection	9961774
26254690	26254713	13	+	27869803	HPAFII	viability after 31 days	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.44977898196628396	[101]	[126,24,NaN]	3	hSpCas9	negative selection	10044219
26254695	26254718	13	-	27869803	HPAFII	viability after 31 days	TGCAGCCCTCGTATTCAAACAGG	CDK8	ENSG00000132964	1.3545862021258177	[764]	[1050,1148,NaN]	8	hSpCas9	negative selection	10044220
26349176	26349199	13	-	27869803	HPAFII	viability after 31 days	CAGCAATTCACCTTACCCAGAGG	CDK8	ENSG00000132964	1.4567374253220513	[438]	[938,389,NaN]	9	hSpCas9	negative selection	10044221
26385301	26385324	13	+	27869803	HPAFII	viability after 31 days	CTGAACTACTTCTTGGAGCAAGG	CDK8	ENSG00000132964	0.9469748135500644	[463]	[345,671,NaN]	7	hSpCas9	negative selection	10044222
26393455	26393478	13	+	27869803	HPAFII	viability after 31 days	TCCTTATCACCATGACCAGCTGG	CDK8	ENSG00000132964	-0.5453325628307617	[117]	[64,23,NaN]	-4	hSpCas9	negative selection	10044223
26254708	26254731	13	+	28162770	P31FUJ	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-3.040157126471983	[6]	[0]	-9	hSpCas9	negative selection	10130791
26400493	26400516	13	-	28162770	P31FUJ	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.2920989058208745	[514]	[740]	3	hSpCas9	negative selection	10130792
26254690	26254713	13	+	28162770	P31FUJ	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.10362546016809868	[197]	[249]	1	hSpCas9	negative selection	10130793
26353778	26353801	13	+	28162770	P31FUJ	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	-0.19958078489896192	[600]	[614]	-2	hSpCas9	negative selection	10130794
26254659	26254682	13	+	28162770	P31FUJ	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.6031706543594941	[105]	[81]	-5	hSpCas9	negative selection	10130795
26353794	26353817	13	-	28162770	P31FUJ	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.2783400630151064	[420]	[599]	3	hSpCas9	negative selection	10130796
26254739	26254762	13	+	28162770	P31FUJ	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.17036119457617332	[182]	[241]	1	hSpCas9	negative selection	10130797
26353847	26353870	13	-	28162770	P31FUJ	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.49623647398019877	[218]	[362]	5	hSpCas9	negative selection	10130798
26393489	26393512	13	+	28162770	P31FUJ	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.34152874457689064	[226]	[337]	4	hSpCas9	negative selection	10130799
26400482	26400505	13	+	28162770	P31FUJ	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.5106328850813853	[177]	[297]	6	hSpCas9	negative selection	10130800
26254708	26254731	13	+	28162770	TF1	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10300157
26400493	26400516	13	-	28162770	TF1	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	NaN	[NaN]	[412]	1	hSpCas9	negative selection	10300158
26254690	26254713	13	+	28162770	TF1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10300159
26353778	26353801	13	+	28162770	TF1	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	NaN	[NaN]	[406]	1	hSpCas9	negative selection	10300160
26254659	26254682	13	+	28162770	TF1	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10300161
26353794	26353817	13	-	28162770	TF1	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10300162
26254739	26254762	13	+	28162770	TF1	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10300163
26353847	26353870	13	-	28162770	TF1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10300164
26393489	26393512	13	+	28162770	TF1	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10300165
26400482	26400505	13	+	28162770	TF1	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10300166
26254708	26254731	13	+	28162770	SKM1	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	1.4999263968653564	[2]	[14]	9	hSpCas9	negative selection	10469523
26400493	26400516	13	-	28162770	SKM1	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.3725470903891295	[141]	[324]	3	hSpCas9	negative selection	10469524
26254690	26254713	13	+	28162770	SKM1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.4130183316421916	[64]	[152]	4	hSpCas9	negative selection	10469525
26353778	26353801	13	+	28162770	SKM1	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.6445019692907936	[147]	[408]	6	hSpCas9	negative selection	10469526
26254659	26254682	13	+	28162770	SKM1	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-1.0335058032157174	[21]	[18]	-6	hSpCas9	negative selection	10469527
26353794	26353817	13	-	28162770	SKM1	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.08488889758651319	[127]	[239]	0	hSpCas9	negative selection	10469528
26254739	26254762	13	+	28162770	SKM1	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.8901959909952586	[46]	[153]	8	hSpCas9	negative selection	10469529
26353847	26353870	13	-	28162770	SKM1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.7927081460932028	[31]	[97]	7	hSpCas9	negative selection	10469530
26393489	26393512	13	+	28162770	SKM1	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	1.0131874322323242	[43]	[156]	8	hSpCas9	negative selection	10469531
26400482	26400505	13	+	28162770	SKM1	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10469532
26254708	26254731	13	+	28162770	SKM1	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	1.4999263968653564	[2]	[14]	9	hSpCas9	negative selection	10638889
26400493	26400516	13	-	28162770	SKM1	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.3725470903891295	[141]	[324]	3	hSpCas9	negative selection	10638890
26254690	26254713	13	+	28162770	SKM1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.4130183316421916	[64]	[152]	4	hSpCas9	negative selection	10638891
26353778	26353801	13	+	28162770	SKM1	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.6445019692907936	[147]	[408]	6	hSpCas9	negative selection	10638892
26254659	26254682	13	+	28162770	SKM1	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-1.0335058032157174	[21]	[18]	-6	hSpCas9	negative selection	10638893
26353794	26353817	13	-	28162770	SKM1	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.08488889758651319	[127]	[239]	0	hSpCas9	negative selection	10638894
26254739	26254762	13	+	28162770	SKM1	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.8901959909952586	[46]	[153]	8	hSpCas9	negative selection	10638895
26353847	26353870	13	-	28162770	SKM1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.7927081460932028	[31]	[97]	7	hSpCas9	negative selection	10638896
26393489	26393512	13	+	28162770	SKM1	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	1.0131874322323242	[43]	[156]	8	hSpCas9	negative selection	10638897
26400482	26400505	13	+	28162770	SKM1	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10638898
26254708	26254731	13	+	28162770	PL21	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-1.9697853869529922	[8]	[0]	-8	hSpCas9	negative selection	10808255
26400493	26400516	13	-	28162770	PL21	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.01510772065679955	[431]	[189]	0	hSpCas9	negative selection	10808256
26254690	26254713	13	+	28162770	PL21	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	1.0162754220891337	[350]	[308]	8	hSpCas9	negative selection	10808257
26353778	26353801	13	+	28162770	PL21	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.4898622848544414	[606]	[370]	4	hSpCas9	negative selection	10808258
26254659	26254682	13	+	28162770	PL21	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	1.280758074697605	[86]	[91]	9	hSpCas9	negative selection	10808259
26353794	26353817	13	-	28162770	PL21	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	1.0530712267038511	[453]	[409]	8	hSpCas9	negative selection	10808260
26254739	26254762	13	+	28162770	PL21	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	2.4049594063778184	[176]	[407]	9	hSpCas9	negative selection	10808261
26353847	26353870	13	-	28162770	PL21	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.30472851576652	[132]	[142]	9	hSpCas9	negative selection	10808262
26393489	26393512	13	+	28162770	PL21	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.7289970133253262	[200]	[144]	6	hSpCas9	negative selection	10808263
26400482	26400505	13	+	28162770	PL21	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.5669219451609429	[151]	[97]	5	hSpCas9	negative selection	10808264
26254708	26254731	13	+	28162770	P31FUJ	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-3.040157126471983	[6]	[0]	-9	hSpCas9	negative selection	10977621
26400493	26400516	13	-	28162770	P31FUJ	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.2920989058208745	[514]	[740]	3	hSpCas9	negative selection	10977622
26254690	26254713	13	+	28162770	P31FUJ	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.10362546016809868	[197]	[249]	1	hSpCas9	negative selection	10977623
26353778	26353801	13	+	28162770	P31FUJ	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	-0.19958078489896192	[600]	[614]	-2	hSpCas9	negative selection	10977624
26254659	26254682	13	+	28162770	P31FUJ	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.6031706543594941	[105]	[81]	-5	hSpCas9	negative selection	10977625
26353794	26353817	13	-	28162770	P31FUJ	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.2783400630151064	[420]	[599]	3	hSpCas9	negative selection	10977626
26254739	26254762	13	+	28162770	P31FUJ	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.17036119457617332	[182]	[241]	1	hSpCas9	negative selection	10977627
26353847	26353870	13	-	28162770	P31FUJ	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.49623647398019877	[218]	[362]	5	hSpCas9	negative selection	10977628
26393489	26393512	13	+	28162770	P31FUJ	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.34152874457689064	[226]	[337]	4	hSpCas9	negative selection	10977629
26400482	26400505	13	+	28162770	P31FUJ	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.5106328850813853	[177]	[297]	6	hSpCas9	negative selection	10977630
26254708	26254731	13	+	28162770	OCIAML5	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-1.3374933980342387	[6]	[4]	-7	hSpCas9	negative selection	11146987
26400493	26400516	13	-	28162770	OCIAML5	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	-0.5671854627319544	[283]	[345]	-4	hSpCas9	negative selection	11146988
26254690	26254713	13	+	28162770	OCIAML5	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.9630978832527408	[161]	[149]	-6	hSpCas9	negative selection	11146989
26353778	26353801	13	+	28162770	OCIAML5	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.07248120070653763	[313]	[595]	0	hSpCas9	negative selection	11146990
26254659	26254682	13	+	28162770	OCIAML5	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.7171369907778884	[50]	[55]	-5	hSpCas9	negative selection	11146991
26353794	26353817	13	-	28162770	OCIAML5	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.017349319325858703	[207]	[379]	0	hSpCas9	negative selection	11146992
26254739	26254762	13	+	28162770	OCIAML5	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	-0.5282288859680031	[150]	[188]	-4	hSpCas9	negative selection	11146993
26353847	26353870	13	-	28162770	OCIAML5	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.07662682888315518	[110]	[189]	0	hSpCas9	negative selection	11146994
26393489	26393512	13	+	28162770	OCIAML5	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	-0.19445876831107473	[141]	[223]	-1	hSpCas9	negative selection	11146995
26400482	26400505	13	+	28162770	OCIAML5	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-0.29390412948655603	[162]	[239]	-2	hSpCas9	negative selection	11146996
26254708	26254731	13	+	28162770	EOL1	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-0.0014516469856888925	[18]	[9]	0	hSpCas9	negative selection	11316353
26400493	26400516	13	-	28162770	EOL1	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.36186671822538474	[513]	[347]	3	hSpCas9	negative selection	11316354
26254690	26254713	13	+	28162770	EOL1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	1.206318739985914	[356]	[433]	8	hSpCas9	negative selection	11316355
26353778	26353801	13	+	28162770	EOL1	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.17268179240396475	[1102]	[654]	1	hSpCas9	negative selection	11316356
26254659	26254682	13	+	28162770	EOL1	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	0.11719284951293052	[174]	[99]	1	hSpCas9	negative selection	11316357
26353794	26353817	13	-	28162770	EOL1	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.7681462142279678	[875]	[785]	6	hSpCas9	negative selection	11316358
26254739	26254762	13	+	28162770	EOL1	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.7175474006510685	[201]	[174]	6	hSpCas9	negative selection	11316359
26353847	26353870	13	-	28162770	EOL1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.0216889299810663	[200]	[214]	8	hSpCas9	negative selection	11316360
26393489	26393512	13	+	28162770	EOL1	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	1.0721049599843924	[259]	[287]	8	hSpCas9	negative selection	11316361
26400482	26400505	13	+	28162770	EOL1	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	1.0434251674224542	[162]	[176]	8	hSpCas9	negative selection	11316362
26254708	26254731	13	+	28162770	MOLM13	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-2.1170731191765775	[5]	[0]	-7	hSpCas9	negative selection	11485719
26400493	26400516	13	-	28162770	MOLM13	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.31107529559320524	[533]	[478]	2	hSpCas9	negative selection	11485720
26254690	26254713	13	+	28162770	MOLM13	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.5458918935458518	[413]	[436]	4	hSpCas9	negative selection	11485721
26353778	26353801	13	+	28162770	MOLM13	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.588098623360243	[678]	[737]	4	hSpCas9	negative selection	11485722
26254659	26254682	13	+	28162770	MOLM13	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	1.110126687617484	[106]	[166]	8	hSpCas9	negative selection	11485723
26353794	26353817	13	-	28162770	MOLM13	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.2826177993669372	[696]	[612]	2	hSpCas9	negative selection	11485724
26254739	26254762	13	+	28162770	MOLM13	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.963520990720877	[321]	[453]	7	hSpCas9	negative selection	11485725
26353847	26353870	13	-	28162770	MOLM13	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.9413190389320674	[246]	[92]	-5	hSpCas9	negative selection	11485726
26393489	26393512	13	+	28162770	MOLM13	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.647092196574902	[309]	[350]	5	hSpCas9	negative selection	11485727
26400482	26400505	13	+	28162770	MOLM13	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-1.2993587795576702	[336]	[98]	-6	hSpCas9	negative selection	11485728
26254708	26254731	13	+	28162770	HEL	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.6427388320003571	[8]	[8]	5	hSpCas9	negative selection	11655085
26400493	26400516	13	-	28162770	HEL	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.7401871721161759	[414]	[443]	6	hSpCas9	negative selection	11655086
26254690	26254713	13	+	28162770	HEL	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.2403381583994385	[340]	[257]	2	hSpCas9	negative selection	11655087
26353778	26353801	13	+	28162770	HEL	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	1.3858212525836877	[658]	[1102]	9	hSpCas9	negative selection	11655088
26254659	26254682	13	+	28162770	HEL	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	0.505235308250422	[153]	[139]	4	hSpCas9	negative selection	11655089
26353794	26353817	13	-	28162770	HEL	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.9421439102615798	[580]	[714]	7	hSpCas9	negative selection	11655090
26254739	26254762	13	+	28162770	HEL	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.5016110948654795	[278]	[252]	4	hSpCas9	negative selection	11655091
26353847	26353870	13	-	28162770	HEL	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.459371567645972	[154]	[272]	9	hSpCas9	negative selection	11655092
26393489	26393512	13	+	28162770	HEL	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	-0.42510381378069445	[282]	[134]	-3	hSpCas9	negative selection	11655093
26400482	26400505	13	+	28162770	HEL	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	-0.46781954314734164	[243]	[112]	-3	hSpCas9	negative selection	11655094
26254708	26254731	13	+	28162770	MV411	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	0.24743755078277552	[16]	[16]	2	hSpCas9	negative selection	11824451
26400493	26400516	13	-	28162770	MV411	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.773388836073296	[340]	[490]	7	hSpCas9	negative selection	11824452
26254690	26254713	13	+	28162770	MV411	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.4133157191623858	[237]	[266]	3	hSpCas9	negative selection	11824453
26353778	26353801	13	+	28162770	MV411	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.023507894307929433	[625]	[535]	0	hSpCas9	negative selection	11824454
26254659	26254682	13	+	28162770	MV411	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	1.4680366902961726	[114]	[267]	9	hSpCas9	negative selection	11824455
26353794	26353817	13	-	28162770	MV411	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	0.5652573513678925	[421]	[525]	5	hSpCas9	negative selection	11824456
26254739	26254762	13	+	28162770	MV411	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.6273712491057031	[155]	[202]	5	hSpCas9	negative selection	11824457
26353847	26353870	13	-	28162770	MV411	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.4599821861628759	[125]	[145]	4	hSpCas9	negative selection	11824458
26393489	26393512	13	+	28162770	MV411	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.6772504027420176	[169]	[228]	6	hSpCas9	negative selection	11824459
26400482	26400505	13	+	28162770	MV411	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.12405513527749318	[121]	[111]	1	hSpCas9	negative selection	11824460
26254708	26254731	13	+	28162770	MONOMAC1	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	11993817
26400493	26400516	13	-	28162770	MONOMAC1	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	-0.7575047858599612	[291]	[197]	-6	hSpCas9	negative selection	11993818
26254690	26254713	13	+	28162770	MONOMAC1	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	-0.25843739172369706	[167]	[160]	-2	hSpCas9	negative selection	11993819
26353778	26353801	13	+	28162770	MONOMAC1	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	-0.2686597748900621	[350]	[333]	-2	hSpCas9	negative selection	11993820
26254659	26254682	13	+	28162770	MONOMAC1	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.04503375361450368	[62]	[69]	0	hSpCas9	negative selection	11993821
26353794	26353817	13	-	28162770	MONOMAC1	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	-0.3013735068742893	[300]	[279]	-3	hSpCas9	negative selection	11993822
26254739	26254762	13	+	28162770	MONOMAC1	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	-2.0180667060142343	[105]	[29]	-8	hSpCas9	negative selection	11993823
26353847	26353870	13	-	28162770	MONOMAC1	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	-0.9428533588080257	[108]	[64]	-6	hSpCas9	negative selection	11993824
26393489	26393512	13	+	28162770	MONOMAC1	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.4683443361169003	[156]	[248]	4	hSpCas9	negative selection	11993825
26400482	26400505	13	+	28162770	MONOMAC1	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.5057621439554605	[93]	[152]	5	hSpCas9	negative selection	11993826
26254708	26254731	13	+	28162770	OCIAML2	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	1.9888017933951359	[0]	[21]	9	hSpCas9	negative selection	12163183
26400493	26400516	13	-	28162770	OCIAML2	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.2984862925277514	[70]	[483]	3	hSpCas9	negative selection	12163184
26254690	26254713	13	+	28162770	OCIAML2	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	0.19095395708190754	[54]	[347]	1	hSpCas9	negative selection	12163185
26353778	26353801	13	+	28162770	OCIAML2	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	0.39016435577690345	[105]	[769]	4	hSpCas9	negative selection	12163186
26254659	26254682	13	+	28162770	OCIAML2	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	0.8632709113112771	[11]	[120]	8	hSpCas9	negative selection	12163187
26353794	26353817	13	-	28162770	OCIAML2	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	1.238431602069722	[76]	[1006]	9	hSpCas9	negative selection	12163188
26254739	26254762	13	+	28162770	OCIAML2	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.08488889758651305	[32]	[193]	0	hSpCas9	negative selection	12163189
26353847	26353870	13	-	28162770	OCIAML2	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	0.6753494805751188	[26]	[238]	6	hSpCas9	negative selection	12163190
26393489	26393512	13	+	28162770	OCIAML2	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	1.4699916276789071	[30]	[475]	9	hSpCas9	negative selection	12163191
26400482	26400505	13	+	28162770	OCIAML2	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	0.4757891345529948	[23]	[184]	4	hSpCas9	negative selection	12163192
26254708	26254731	13	+	28162770	OCIAML3	viability	GAGGGCTGCAAAGTTGGCCGAGG	CDK8	ENSG00000132964	-2.33097323449037	[4]	[2]	-9	hSpCas9	negative selection	12332549
26400493	26400516	13	-	28162770	OCIAML3	viability	GTCCTGCATAGCCTGTTCTGAGG	CDK8	ENSG00000132964	0.9610843308148556	[121]	[716]	8	hSpCas9	negative selection	12332550
26254690	26254713	13	+	28162770	OCIAML3	viability	GAGGACCTGTTTGAATACGAGGG	CDK8	ENSG00000132964	1.139346700289664	[59]	[398]	8	hSpCas9	negative selection	12332551
26353778	26353801	13	+	28162770	OCIAML3	viability	GAAGCCAGTTCAGTTACCTCGGG	CDK8	ENSG00000132964	1.2207419419045633	[138]	[977]	8	hSpCas9	negative selection	12332552
26254659	26254682	13	+	28162770	OCIAML3	viability	AGTGAAGCTGAGCAGCGAGCGGG	CDK8	ENSG00000132964	-0.1677428856220653	[15]	[42]	-1	hSpCas9	negative selection	12332553
26353794	26353817	13	-	28162770	OCIAML3	viability	AGTGACTTCACCATTCCCCGAGG	CDK8	ENSG00000132964	1.491911385860839	[109]	[933]	9	hSpCas9	negative selection	12332554
26254739	26254762	13	+	28162770	OCIAML3	viability	GTCACGTCTACAAAGCCAAGAGG	CDK8	ENSG00000132964	0.9478861385051071	[50]	[296]	7	hSpCas9	negative selection	12332555
26353847	26353870	13	-	28162770	OCIAML3	viability	GCAACACCCAGTTAGCATGCAGG	CDK8	ENSG00000132964	1.380725601065407	[35]	[282]	9	hSpCas9	negative selection	12332556
26393489	26393512	13	+	28162770	OCIAML3	viability	AATGTAATGGGATTTCCTGCAGG	CDK8	ENSG00000132964	0.6253053880803128	[66]	[311]	6	hSpCas9	negative selection	12332557
26400482	26400505	13	+	28162770	OCIAML3	viability	AAAGCGAATTACCTCAGAACAGG	CDK8	ENSG00000132964	1.4741638623174163	[30]	[259]	9	hSpCas9	negative selection	12332558