Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 84902
  • Symbol: Cep89
  • Description: centrosomal protein 89
DataSource: http://genomecrispr.dkfz.de/#!/results/Cep89

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
32966375 32966398 19 + 26472758 Jiyoye viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.7854696964365222 [159] [34] -8 hSpCas9 negative selection 30227
32881872 32881895 19 - 26472758 Jiyoye viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -0.7697023805782057 [51] [22] -5 hSpCas9 negative selection 30228
32953697 32953720 19 - 26472758 Jiyoye viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.8365681737617872 [74] [100] 6 hSpCas9 negative selection 30229
32937642 32937665 19 + 26472758 Jiyoye viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 1.616628747134823 [127] [295] 8 hSpCas9 negative selection 30230
32931521 32931544 19 - 26472758 Jiyoye viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 -0.007862117772970372 [123] [92] 0 hSpCas9 negative selection 30231
32931508 32931531 19 - 26472758 Jiyoye viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.02345897282398901 [61] [45] 0 hSpCas9 negative selection 30232
32915482 32915505 19 - 26472758 Jiyoye viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -0.7303281422440617 [87] [39] -5 hSpCas9 negative selection 30233
32915385 32915408 19 - 26472758 Jiyoye viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.21431299524039682 [59] [38] -1 hSpCas9 negative selection 30234
32901279 32901302 19 - 26472758 Jiyoye viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.014857958727113152 [104] [79] 0 hSpCas9 negative selection 30235
32881981 32882004 19 - 26472758 Jiyoye viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.20746018031051516 [262] [228] 1 hSpCas9 negative selection 30236
32966375 32966398 19 + 26472758 KBM7 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.3787565712635175 [424,283] [79,47] -7 hSpCas9 negative selection 221345
32881872 32881895 19 - 26472758 KBM7 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 0.3275324387165257 [143,213] [216,10] 3 hSpCas9 negative selection 221346
32953697 32953720 19 - 26472758 KBM7 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.5515931415867483 [386,290] [346,127] 6 hSpCas9 negative selection 221347
32937642 32937665 19 + 26472758 KBM7 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.43864931387491224 [992,767] [782,353] 5 hSpCas9 negative selection 221348
32931521 32931544 19 - 26472758 KBM7 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.5868814090796427 [412,270] [188,280] 6 hSpCas9 negative selection 221349
32931508 32931531 19 - 26472758 KBM7 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.4135839806905992 [138,140] [45,52] -4 hSpCas9 negative selection 221350
32915482 32915505 19 - 26472758 KBM7 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -0.4497650306640756 [334,308] [149,75] -4 hSpCas9 negative selection 221351
32915385 32915408 19 - 26472758 KBM7 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.11671251185724096 [114,121] [62,58] 1 hSpCas9 negative selection 221352
32901279 32901302 19 - 26472758 KBM7 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.5018924121423596 [342,517] [331,259] 5 hSpCas9 negative selection 221353
32881981 32882004 19 - 26472758 KBM7 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.6730784256322344 [1120,963] [753,801] 7 hSpCas9 negative selection 221354
32966375 32966398 19 + 26472758 Raji viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.1336245641301954 [207] [21] -7 hSpCas9 negative selection 412463
32881872 32881895 19 - 26472758 Raji viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -0.8468127750132757 [92] [11] -6 hSpCas9 negative selection 412464
32953697 32953720 19 - 26472758 Raji viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.31597015718501686 [134] [38] 3 hSpCas9 negative selection 412465
32937642 32937665 19 + 26472758 Raji viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -0.13011577835305677 [447] [94] -1 hSpCas9 negative selection 412466
32931521 32931544 19 - 26472758 Raji viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.3368653814963667 [231] [67] 3 hSpCas9 negative selection 412467
32931508 32931531 19 - 26472758 Raji viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.3769905951308796 [72] [21] 3 hSpCas9 negative selection 412468
32915482 32915505 19 - 26472758 Raji viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.6608678046215875 [138] [50] 6 hSpCas9 negative selection 412469
32915385 32915408 19 - 26472758 Raji viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.14895621788618607 [42] [8] -1 hSpCas9 negative selection 412470
32901279 32901302 19 - 26472758 Raji viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 -0.6520766965796931 [236] [34] -5 hSpCas9 negative selection 412471
32881981 32882004 19 - 26472758 Raji viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.4724958093207611 [440] [141] 4 hSpCas9 negative selection 412472
32966375 32966398 19 + 26472758 K562 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -3.2053841897730737 [447] [40] -8 hSpCas9 negative selection 603581
32881872 32881895 19 - 26472758 K562 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -2.2665431916109324 [227] [39] -7 hSpCas9 negative selection 603582
32953697 32953720 19 - 26472758 K562 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.6109577092541008 [241] [311] 5 hSpCas9 negative selection 603583
32937642 32937665 19 + 26472758 K562 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.48677956523549093 [737] [872] 4 hSpCas9 negative selection 603584
32931521 32931544 19 - 26472758 K562 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.3325100572913038 [269] [286] 2 hSpCas9 negative selection 603585
32931508 32931531 19 - 26472758 K562 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 1.1589006564803896 [138] [261] 8 hSpCas9 negative selection 603586
32915482 32915505 19 - 26472758 K562 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.5109337022352027 [206] [248] 4 hSpCas9 negative selection 603587
32915385 32915408 19 - 26472758 K562 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.3267379735296785 [103] [69] -2 hSpCas9 negative selection 603588
32901279 32901302 19 - 26472758 K562 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.6211677422209169 [314] [408] 5 hSpCas9 negative selection 603589
32881981 32882004 19 - 26472758 K562 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.6903313438076268 [808] [1101] 5 hSpCas9 negative selection 603590
32918223 32918246 19 - 26627737 DLD1 viability CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.22428805792387685 [741] [264,287,261] 2 hSpCas9 negative selection 803954
32926953 32926976 19 - 26627737 DLD1 viability ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.6885210112961326 [143] [48,6,26] -6 hSpCas9 negative selection 803955
32933447 32933470 19 - 26627737 DLD1 viability AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -0.11537005518239257 [420] [100,93,161] -1 hSpCas9 negative selection 803956
32953692 32953715 19 - 26627737 DLD1 viability TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.48009017853843683 [1206] [369,300,158] -5 hSpCas9 negative selection 803957
32959983 32960006 19 - 26627737 DLD1 viability CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.20450083552306178 [552] [223,103,123] -2 hSpCas9 negative selection 803958
32966413 32966436 19 + 26627737 DLD1 viability AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -1.7744524449690944 [345] [15,32,43] -8 hSpCas9 negative selection 803959
32918223 32918246 19 - 26627737 GBM cells viability after 5 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.23628340014525118 [538] [341,338] 3 hSpCas9 negative selection 886269
32926953 32926976 19 - 26627737 GBM cells viability after 5 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.03968558045017101 [114] [59,59] 0 hSpCas9 negative selection 886270
32933447 32933470 19 - 26627737 GBM cells viability after 5 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.1955308812438607 [275] [171,166] 3 hSpCas9 negative selection 886271
32953692 32953715 19 - 26627737 GBM cells viability after 5 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.2606218717584028 [371] [283,193] 4 hSpCas9 negative selection 886272
32959983 32960006 19 - 26627737 GBM cells viability after 5 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.354470360914389 [297] [114,134] -5 hSpCas9 negative selection 886273
32966413 32966436 19 + 26627737 GBM cells viability after 5 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.05801740322242832 [98] [36,64] -1 hSpCas9 negative selection 886274
32918223 32918246 19 - 26627737 GBM cells viability after 13 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.09475721344413235 [538] [367,266] 1 hSpCas9 negative selection 968584
32926953 32926976 19 - 26627737 GBM cells viability after 13 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.6739104469964221 [114] [53,26] -7 hSpCas9 negative selection 968585
32933447 32933470 19 - 26627737 GBM cells viability after 13 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.1738302711212561 [275] [158,176] 2 hSpCas9 negative selection 968586
32953692 32953715 19 - 26627737 GBM cells viability after 13 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.06295067189144488 [371] [222,168] 0 hSpCas9 negative selection 968587
32959983 32960006 19 - 26627737 GBM cells viability after 13 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.5491628374922826 [297] [147,79] -6 hSpCas9 negative selection 968588
32966413 32966436 19 + 26627737 GBM cells viability after 13 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.7843573090662472 [98] [86,96] 8 hSpCas9 negative selection 968589
32918223 32918246 19 - 26627737 GBM cells viability after 21 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.36591501990332786 [538] [403,352] 4 hSpCas9 negative selection 1050899
32926953 32926976 19 - 26627737 GBM cells viability after 21 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.1827316944120283 [114] [53,55] -2 hSpCas9 negative selection 1050900
32933447 32933470 19 - 26627737 GBM cells viability after 21 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 1.0086265960504779 [275] [308,294] 8 hSpCas9 negative selection 1050901
32953692 32953715 19 - 26627737 GBM cells viability after 21 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.19421073680064938 [371] [225,235] 2 hSpCas9 negative selection 1050902
32959983 32960006 19 - 26627737 GBM cells viability after 21 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.49079917217437075 [297] [121,108] -4 hSpCas9 negative selection 1050903
32966413 32966436 19 + 26627737 GBM cells viability after 21 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.3539313062697083 [98] [137,136] 9 hSpCas9 negative selection 1050904
32918223 32918246 19 - 26627737 RPE1 viability after 9 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.5211206757837022 [1429] [593,704] 3 hSpCas9 negative selection 1133214
32926953 32926976 19 - 26627737 RPE1 viability after 9 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 1.162155423273084 [128] [92,86] 7 hSpCas9 negative selection 1133215
32933447 32933470 19 - 26627737 RPE1 viability after 9 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -1.3241054058769466 [1586] [166,238] -7 hSpCas9 negative selection 1133216
32953692 32953715 19 - 26627737 RPE1 viability after 9 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.2796372054086097 [1316] [202,515] -2 hSpCas9 negative selection 1133217
32959983 32960006 19 - 26627737 RPE1 viability after 9 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -1.680831193387208 [1043] [135,57] -8 hSpCas9 negative selection 1133218
32966413 32966436 19 + 26627737 RPE1 viability after 9 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 3.017188144202937 [21] [91,8] 9 hSpCas9 negative selection 1133219
32918223 32918246 19 - 26627737 RPE1 viability after 12 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.9419565367376052 [1429] [808,662] 6 hSpCas9 negative selection 1215529
32926953 32926976 19 - 26627737 RPE1 viability after 12 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 1.0258964657769571 [128] [72,67] 6 hSpCas9 negative selection 1215530
32933447 32933470 19 - 26627737 RPE1 viability after 12 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -1.0258573691185982 [1586] [154,266] -6 hSpCas9 negative selection 1215531
32953692 32953715 19 - 26627737 RPE1 viability after 12 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.045344230567438526 [1316] [304,382] 0 hSpCas9 negative selection 1215532
32959983 32960006 19 - 26627737 RPE1 viability after 12 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -2.0232701281185776 [1043] [85,50] -8 hSpCas9 negative selection 1215533
32966413 32966436 19 + 26627737 RPE1 viability after 12 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 2.958448467269803 [21] [60,29] 9 hSpCas9 negative selection 1215534
32918223 32918246 19 - 26627737 RPE1 viability after 15 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.8277212846697978 [1429] [747,688] 5 hSpCas9 negative selection 1297844
32926953 32926976 19 - 26627737 RPE1 viability after 15 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 1.1361577621135643 [128] [152,9] 6 hSpCas9 negative selection 1297845
32933447 32933470 19 - 26627737 RPE1 viability after 15 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -1.1165983124347274 [1586] [204,208] -6 hSpCas9 negative selection 1297846
32953692 32953715 19 - 26627737 RPE1 viability after 15 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.25991648449395843 [1316] [496,396] 1 hSpCas9 negative selection 1297847
32959983 32960006 19 - 26627737 RPE1 viability after 15 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.7950392121746459 [1043] [214,126] -5 hSpCas9 negative selection 1297848
32966413 32966436 19 + 26627737 RPE1 viability after 15 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 2.608267826193584 [21] [68,7] 9 hSpCas9 negative selection 1297849
32918223 32918246 19 - 26627737 RPE1 viability after 18 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.7677848915933997 [1429] [702,607] 5 hSpCas9 negative selection 1380159
32926953 32926976 19 - 26627737 RPE1 viability after 18 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 1.0522542909172692 [128] [106,34] 6 hSpCas9 negative selection 1380160
32933447 32933470 19 - 26627737 RPE1 viability after 18 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -1.3825749322023266 [1586] [200,124] -7 hSpCas9 negative selection 1380161
32953692 32953715 19 - 26627737 RPE1 viability after 18 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.18148520336091345 [1316] [229,587] 1 hSpCas9 negative selection 1380162
32959983 32960006 19 - 26627737 RPE1 viability after 18 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -1.9921547287825838 [1043] [50,91] -8 hSpCas9 negative selection 1380163
32966413 32966436 19 + 26627737 RPE1 viability after 18 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 3.0150566889590213 [21] [76,16] 9 hSpCas9 negative selection 1380164
32918223 32918246 19 - 26627737 HeLa viability after 8 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.8904346901128454 [688] [512,427,705] 7 hSpCas9 negative selection 1462474
32926953 32926976 19 - 26627737 HeLa viability after 8 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.48493460427254753 [92] [50,65,51] 4 hSpCas9 negative selection 1462475
32933447 32933470 19 - 26627737 HeLa viability after 8 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.41457598494384246 [453] [229,294,257] 4 hSpCas9 negative selection 1462476
32953692 32953715 19 - 26627737 HeLa viability after 8 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.1340919221719421 [690] [349,233,255] -1 hSpCas9 negative selection 1462477
32959983 32960006 19 - 26627737 HeLa viability after 8 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.2058412630600604 [292] [179,159,110] 2 hSpCas9 negative selection 1462478
32966413 32966436 19 + 26627737 HeLa viability after 8 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.9587333294313655 [106] [167,110,14] 7 hSpCas9 negative selection 1462479
32918223 32918246 19 - 26627737 HeLa viability after 12 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.826774981072066 [688] [385,435,696] 6 hSpCas9 negative selection 1544789
32926953 32926976 19 - 26627737 HeLa viability after 12 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.07420494622522567 [92] [37,33,49] 0 hSpCas9 negative selection 1544790
32933447 32933470 19 - 26627737 HeLa viability after 12 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.5835910229265311 [453] [433,223,195] 5 hSpCas9 negative selection 1544791
32953692 32953715 19 - 26627737 HeLa viability after 12 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.6003758683450303 [690] [393,401,504] 5 hSpCas9 negative selection 1544792
32959983 32960006 19 - 26627737 HeLa viability after 12 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.3387678620241927 [292] [47,65,174] -3 hSpCas9 negative selection 1544793
32966413 32966436 19 + 26627737 HeLa viability after 12 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.30091098348835676 [106] [0,90,65] 2 hSpCas9 negative selection 1544794
32918223 32918246 19 - 26627737 HeLa viability after 15 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.6846727738337411 [688] [277,429,662] 5 hSpCas9 negative selection 1627104
32926953 32926976 19 - 26627737 HeLa viability after 15 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.9673415861786683 [92] [79,67,73] 7 hSpCas9 negative selection 1627105
32933447 32933470 19 - 26627737 HeLa viability after 15 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.7471981774884182 [453] [329,355,238] 6 hSpCas9 negative selection 1627106
32953692 32953715 19 - 26627737 HeLa viability after 15 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.5195691549101612 [690] [280,603,319] 4 hSpCas9 negative selection 1627107
32959983 32960006 19 - 26627737 HeLa viability after 15 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.16745699856913848 [292] [61,107,240] 1 hSpCas9 negative selection 1627108
32966413 32966436 19 + 26627737 HeLa viability after 15 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.2298394367432919 [106] [49,144,112] 8 hSpCas9 negative selection 1627109
32918223 32918246 19 - 26627737 HeLa viability after 18 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.7062751184547434 [688] [190,366,662] 5 hSpCas9 negative selection 1709419
32926953 32926976 19 - 26627737 HeLa viability after 18 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.9150880587804022 [92] [51,51,73] 7 hSpCas9 negative selection 1709420
32933447 32933470 19 - 26627737 HeLa viability after 18 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.7485339531540158 [453] [208,310,238] 6 hSpCas9 negative selection 1709421
32953692 32953715 19 - 26627737 HeLa viability after 18 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.5359481082589922 [690] [191,506,319] 4 hSpCas9 negative selection 1709422
32959983 32960006 19 - 26627737 HeLa viability after 18 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.14434377490903982 [292] [40,84,240] 1 hSpCas9 negative selection 1709423
32966413 32966436 19 + 26627737 HeLa viability after 18 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.2414130528369869 [106] [35,118,112] 8 hSpCas9 negative selection 1709424
32918223 32918246 19 - 26627737 HCT116 viability after 6 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.2368928037046878 [1364] [297,227] 1 hSpCas9 negative selection 1791734
32926953 32926976 19 - 26627737 HCT116 viability after 6 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.01761811154625814 [206] [84,2] 0 hSpCas9 negative selection 1791735
32933447 32933470 19 - 26627737 HCT116 viability after 6 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.6713769623046255 [764] [70,257] 4 hSpCas9 negative selection 1791736
32953692 32953715 19 - 26627737 HCT116 viability after 6 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.554290652140252 [1238] [412,215] 3 hSpCas9 negative selection 1791737
32959983 32960006 19 - 26627737 HCT116 viability after 6 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.6878891557033837 [899] [43,111] -4 hSpCas9 negative selection 1791738
32966413 32966436 19 + 26627737 HCT116 viability after 6 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.6984493360720355 [191] [28,59] 4 hSpCas9 negative selection 1791739
32918223 32918246 19 - 26627737 HCT116 viability after 8 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.3746046730357029 [635] [430,505,425] 4 hSpCas9 negative selection 1874049
32926953 32926976 19 - 26627737 HCT116 viability after 8 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.06563930985654709 [71] [19,47,55] 0 hSpCas9 negative selection 1874050
32933447 32933470 19 - 26627737 HCT116 viability after 8 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.5294993779792525 [309] [269,296,173] 5 hSpCas9 negative selection 1874051
32953692 32953715 19 - 26627737 HCT116 viability after 8 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.15354940523776084 [709] [368,293,391] -2 hSpCas9 negative selection 1874052
32959983 32960006 19 - 26627737 HCT116 viability after 8 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.1718112547149887 [331] [239,119,128] -2 hSpCas9 negative selection 1874053
32966413 32966436 19 + 26627737 HCT116 viability after 8 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.5347637041105024 [77] [28,30,28] -6 hSpCas9 negative selection 1874054
32918223 32918246 19 - 26627737 HCT116 viability after 9 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.2932429621677577 [1364] [597,326] 2 hSpCas9 negative selection 1956364
32926953 32926976 19 - 26627737 HCT116 viability after 9 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.5945833632648747 [206] [6,59] -4 hSpCas9 negative selection 1956365
32933447 32933470 19 - 26627737 HCT116 viability after 9 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -0.29171183545423274 [764] [86,229] -2 hSpCas9 negative selection 1956366
32953692 32953715 19 - 26627737 HCT116 viability after 9 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.3039511373379067 [1238] [556,290] 2 hSpCas9 negative selection 1956367
32959983 32960006 19 - 26627737 HCT116 viability after 9 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -1.3392094238553094 [899] [56,124] -7 hSpCas9 negative selection 1956368
32966413 32966436 19 + 26627737 HCT116 viability after 9 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.33175824760273076 [191] [49,75] 2 hSpCas9 negative selection 1956369
32918223 32918246 19 - 26627737 HCT116 viability after 12 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 -0.2752509601743447 [635] [176,471,192] -3 hSpCas9 negative selection 2038679
32926953 32926976 19 - 26627737 HCT116 viability after 12 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.06888497482517253 [71] [42,48,26] 0 hSpCas9 negative selection 2038680
32933447 32933470 19 - 26627737 HCT116 viability after 12 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.36736524991218794 [309] [220,229,178] 3 hSpCas9 negative selection 2038681
32953692 32953715 19 - 26627737 HCT116 viability after 12 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.11070884258108293 [709] [322,317,396] -1 hSpCas9 negative selection 2038682
32959983 32960006 19 - 26627737 HCT116 viability after 12 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.23121118470173058 [331] [222,253,136] 2 hSpCas9 negative selection 2038683
32966413 32966436 19 + 26627737 HCT116 viability after 12 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 0.089577261872263 [77] [68,17,40] 1 hSpCas9 negative selection 2038684
32918223 32918246 19 - 26627737 HCT116 viability after 15 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.07294156344081126 [635] [419,357,378] 0 hSpCas9 negative selection 2120994
32926953 32926976 19 - 26627737 HCT116 viability after 15 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.6244146050400277 [71] [23,18,36] -6 hSpCas9 negative selection 2120995
32933447 32933470 19 - 26627737 HCT116 viability after 15 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.4022656229095328 [309] [332,170,213] 4 hSpCas9 negative selection 2120996
32953692 32953715 19 - 26627737 HCT116 viability after 15 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.26197847658062257 [709] [407,330,289] -3 hSpCas9 negative selection 2120997
32959983 32960006 19 - 26627737 HCT116 viability after 15 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.7873111987167858 [331] [197,109,34] -7 hSpCas9 negative selection 2120998
32966413 32966436 19 + 26627737 HCT116 viability after 15 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.653957686348188 [77] [32,27,24] -6 hSpCas9 negative selection 2120999
32918223 32918246 19 - 26627737 HCT116 viability after 18 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 -0.21078619277486754 [635] [216,285,293] -2 hSpCas9 negative selection 2203309
32926953 32926976 19 - 26627737 HCT116 viability after 18 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.8451664826458145 [71] [24,5,164] 6 hSpCas9 negative selection 2203310
32933447 32933470 19 - 26627737 HCT116 viability after 18 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.13179419500202422 [309] [148,209,128] 1 hSpCas9 negative selection 2203311
32953692 32953715 19 - 26627737 HCT116 viability after 18 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.973142967807928 [709] [178,194,147] -7 hSpCas9 negative selection 2203312
32959983 32960006 19 - 26627737 HCT116 viability after 18 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.1823187824139389 [331] [205,117,99] -2 hSpCas9 negative selection 2203313
32966413 32966436 19 + 26627737 HCT116 viability after 18 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.6990103290853147 [77] [10,16,42] -6 hSpCas9 negative selection 2203314
32919117 32919140 19 - 25494202 A375 resistance to PLX-4720 (puromycin) GCCGAGGCGGGCAGATCACGGGG CEP89 ENSG00000121289 1.6160323087037833 [141,31] [85,27] 6 dCas9-VP64 positive selection 2418277
32939205 32939228 19 + 25494202 A375 resistance to PLX-4720 (puromycin) CACACCACTGCACTCCAGCCCGG CEP89 ENSG00000121289 -0.6897978744123147 [436,52] [50,12] -4 dCas9-VP64 positive selection 2457787
32919117 32919140 19 - 25494202 A375 resistance to PLX-4720 (zeocin) GCCGAGGCGGGCAGATCACGGGG CEP89 ENSG00000121289 0.03329666584269164 [29,118] [13,33] 0 dCas9-VP64 positive selection 2513532
32939205 32939228 19 + 25494202 A375 resistance to PLX-4720 (zeocin) CACACCACTGCACTCCAGCCCGG CEP89 ENSG00000121289 0.2274396231328648 [285,212] [141,51] 1 dCas9-VP64 positive selection 2553042
32959983 32960006 19 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.24132361504986294 [3,2] [1,2] -3 hSpCas9 positive selection 2978701
32948279 32948302 19 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 0.19721579431331554 [4,4] [3,4] 4 hSpCas9 positive selection 2978702
32937643 32937666 19 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -0.1879383538205001 [2,3] [3,1] -3 hSpCas9 positive selection 2978703
32939854 32939877 19 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 0.16957016915882273 [5,5] [4,5] 3 hSpCas9 positive selection 2978704
32959983 32960006 19 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.05962562676264349 [3,3] [2,1] -1 hSpCas9 positive selection 3046559
32948279 32948302 19 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 -0.48769758119012185 [4,4] [3,0] -7 hSpCas9 positive selection 3046560
32937643 32937666 19 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -0.11806047710722742 [2,2] [2,0] -2 hSpCas9 positive selection 3046561
32939854 32939877 19 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 0.25973652406447734 [5,5] [4,3] 4 hSpCas9 positive selection 3046562
32953669 32953692 - 24336571 A375 resistance to PLX after 7 days AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 -0.1528695133045208 [27,29] [25,25] -5 hSpCas9 positive selection 3105092
32953697 32953720 - 24336571 A375 resistance to PLX after 7 days GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.034712424015135857 [12,10] [12,9] -1 hSpCas9 positive selection 3105093
32966351 32966374 + 24336571 A375 resistance to PLX after 7 days GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 0.0684358086143051 [20,26] [23,25] 2 hSpCas9 positive selection 3105094
32953669 32953692 - 24336571 A375 resistance to PLX after 14 days AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 0.829653478925326 [28,25] [21,23] 7 hSpCas9 positive selection 3162885
32953697 32953720 - 24336571 A375 resistance to PLX after 14 days GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.22440365623241448 [8,16] [5,3] -2 hSpCas9 positive selection 3162886
32966351 32966374 + 24336571 A375 resistance to PLX after 14 days GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 1.388268908702507 [17,32] [29,32] 8 hSpCas9 positive selection 3162887
32953669 32953692 - 24336571 A375 viability after 7 days AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 0.35108561292369933 [23] [27,29] 5 hSpCas9 negative selection 3220678
32953697 32953720 - 24336571 A375 viability after 7 days GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.12305683063876309 [13] [12,10] -2 hSpCas9 negative selection 3220679
32966351 32966374 + 24336571 A375 viability after 7 days GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 0.06885942420952795 [23] [20,26] 1 hSpCas9 negative selection 3220680
32953669 32953692 - 24336571 A375 viability after 14 days AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 0.28887217605233484 [23] [28,25] 4 hSpCas9 negative selection 3278471
32953697 32953720 - 24336571 A375 viability after 14 days GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.03339533829939119 [13] [8,16] 0 hSpCas9 negative selection 3278472
32966351 32966374 + 24336571 A375 viability after 14 days GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 0.18093700104141197 [23] [17,32] 2 hSpCas9 negative selection 3278473
32953681 32953704 19 + 27383988 293T resistance to West Nile virus (flavivirus) ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 2.7416298082767576 [180,161] [0,13] 8 hSpCas9 positive selection 3342773
32953632 32953655 19 + 27383988 293T resistance to West Nile virus (flavivirus) CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.2931942510816786 [182,191] [0,0] -2 hSpCas9 positive selection 3342774
32966427 32966450 19 + 27383988 293T resistance to West Nile virus (flavivirus) CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.9824799009569823 [66,87] [0,0] 4 hSpCas9 positive selection 3342775
32966418 32966441 19 - 27383988 293T resistance to West Nile virus (flavivirus) TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.7181674003378037 [278,278] [2,2] 3 hSpCas9 positive selection 3362007
32948350 32948373 19 - 27383988 293T resistance to West Nile virus (flavivirus) AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 -0.9521271541831147 [295,295] [0,0] -6 hSpCas9 positive selection 3362008
32948343 32948366 19 + 27383988 293T resistance to West Nile virus (flavivirus) CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -1.1089960027999806 [329,329] [0,0] -7 hSpCas9 positive selection 3362009
32959983 32960006 19 - 26780180 HT29 viability (Avana library 4 designs) CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 1.21927536271925 [] [] 5 hSpCas9 negative selection 3415043
32948279 32948302 19 - 26780180 HT29 viability (Avana library 4 designs) GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 1.4875781021427 [] [] 6 hSpCas9 negative selection 3415044
32937642 32937665 19 + 26780180 HT29 viability (Avana library 4 designs) GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.833457112049935 [] [] 3 hSpCas9 negative selection 3415045
32939853 32939876 19 + 26780180 HT29 viability (Avana library 4 designs) TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 -0.0252869552134592 [] [] 0 hSpCas9 negative selection 3415046
32948279 32948302 19 - 26780180 A375 viability (Avana lentiCRISPRv2) GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 -3.65492835099047 [] [] -4 hSpCas9 negative selection 3491855
32939853 32939876 19 + 26780180 A375 viability (Avana lentiCRISPRv2) TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 -16.89676606713 [] [] -9 hSpCas9 negative selection 3491856
32937642 32937665 19 + 26780180 A375 viability (Avana lentiCRISPRv2) GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 3.90870771682154 [] [] 6 hSpCas9 negative selection 3491857
32959983 32960006 19 - 26780180 A375 viability (Avana lentiCRISPRv2) CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.230114693910963 [] [] 0 hSpCas9 negative selection 3491858
32926953 32926976 19 - 26780180 A375 viability (Avana lentiCRISPRv2) ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.6253132732964 [] [] -1 hSpCas9 negative selection 3491859
32953697 32953720 19 - 26780180 A375 viability (Avana lentiCRISPRv2) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 1.66526281579493 [] [] 2 hSpCas9 negative selection 3491860
32948279 32948302 19 - 26780180 A375 viability (Avana lentiGuide) GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 6.38883701415409 [] [] 5 hSpCas9 negative selection 3600514
32939853 32939876 19 + 26780180 A375 viability (Avana lentiGuide) TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 -3.64582008564552 [] [] -6 hSpCas9 negative selection 3600515
32937642 32937665 19 + 26780180 A375 viability (Avana lentiGuide) GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -5.48422862161015 [] [] -8 hSpCas9 negative selection 3600516
32959983 32960006 19 - 26780180 A375 viability (Avana lentiGuide) CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -2.8950612928279 [] [] -5 hSpCas9 negative selection 3600517
32926953 32926976 19 - 26780180 A375 viability (Avana lentiGuide) ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 7.26967615150521 [] [] 6 hSpCas9 negative selection 3600518
32953697 32953720 19 - 26780180 A375 viability (Avana lentiGuide) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 3.67770589904901 [] [] 3 hSpCas9 negative selection 3600519
32948279 32948302 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 -0.13100512803279643 [5] [4,5] -2 hSpCas9 positive selection 3709173
32939853 32939876 19 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 -0.709214291391598 [10] [6,5] -7 hSpCas9 positive selection 3709174
32937642 32937665 19 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -0.028788440024481957 [4] [5,3] 0 hSpCas9 positive selection 3709175
32959983 32960006 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.06795362422696935 [4] [4,4] 1 hSpCas9 positive selection 3709176
32926953 32926976 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.10367632886578897 [5] [4,4] -2 hSpCas9 positive selection 3709177
32953697 32953720 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.04217526212195057 [4] [5,4] 1 hSpCas9 positive selection 3709178
32948279 32948302 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTCCCCTCCTGCACCACAGCGG CEP89 ENSG00000121289 -0.28468287032059153 [6] [3,5] -4 hSpCas9 positive selection 3817780
32939853 32939876 19 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTACCTTTAAATTCAGAACAGGG CEP89 ENSG00000121289 0.0882436758185563 [7] [7,4] 2 hSpCas9 positive selection 3817781
32937642 32937665 19 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 -0.03976744434556828 [4] [2,5] 0 hSpCas9 positive selection 3817782
32959983 32960006 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.018594480557059728 [4] [4,3] 0 hSpCas9 positive selection 3817783
32926953 32926976 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 0.09792916592605598 [5] [4,5] 2 hSpCas9 positive selection 3817784
32953697 32953720 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.033311987831612454 [5] [5,3] 0 hSpCas9 positive selection 3817785
32948350 32948373 19 - 26780180 A375 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 1.19750443476883 [] [] 6 hSpCas9 negative selection 3925932
32953681 32953704 19 + 26780180 A375 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.918729255813695 [] [] 4 hSpCas9 negative selection 3925933
32966427 32966450 19 + 26780180 A375 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.136099141827005 [] [] 0 hSpCas9 negative selection 3925934
32953632 32953655 19 + 26780180 A375 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 1.34041088523839 [] [] 7 hSpCas9 negative selection 3925935
32948343 32948366 19 + 26780180 A375 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.798847355301187 [] [] 3 hSpCas9 negative selection 3925936
32966418 32966441 19 - 26780180 A375 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 1.3532230695862 [] [] 7 hSpCas9 negative selection 3925937
32948350 32948373 19 - 26780180 HT29 viability (GeCKOv2 library) AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 1.61906143265697 [] [] 8 hSpCas9 negative selection 4033898
32953681 32953704 19 + 26780180 HT29 viability (GeCKOv2 library) ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.554100437206693 [] [] 1 hSpCas9 negative selection 4033899
32966427 32966450 19 + 26780180 HT29 viability (GeCKOv2 library) CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.656858508007349 [] [] 2 hSpCas9 negative selection 4033900
32953632 32953655 19 + 26780180 HT29 viability (GeCKOv2 library) CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 1.15848424752355 [] [] 5 hSpCas9 negative selection 4033901
32948343 32948366 19 + 26780180 HT29 viability (GeCKOv2 library) CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.656131862395023 [] [] 2 hSpCas9 negative selection 4033902
32966418 32966441 19 - 26780180 HT29 viability (GeCKOv2 library) TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 1.21445098626249 [] [] 6 hSpCas9 negative selection 4033903
32953669 32953692 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 0.2617054752083707 [4] [3,4] 6 hSpCas9 positive selection 4127155
32953697 32953720 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.05407556276690264 [3] [1,2] -1 hSpCas9 positive selection 4127156
32966351 32966374 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 0.3005330352216526 [4] [3,4] 7 hSpCas9 positive selection 4127158
32953669 32953692 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AATTGGGGGATGTCAGTGCCCGG CEP89 ENSG00000121289 0.20916630983532766 [3] [2,3,1,0] 1 hSpCas9 positive selection 4191177
32953697 32953720 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.107628306083287 [3] [0,1,4,0] -1 hSpCas9 positive selection 4191178
32966351 32966374 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GATACTCACCTTGGTCTCTCTGG CEP89 ENSG00000121289 0.18223329123117443 [3] [2,2,3,0] 1 hSpCas9 positive selection 4191180
32953681 32953704 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.10444878107894132 [3] [3,1] 2 hSpCas9 positive selection 4262873
32953632 32953655 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.10467784413853454 [3] [3,2] 2 hSpCas9 positive selection 4262874
32966427 32966450 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.904858042910399 [2] [3,3] 9 hSpCas9 positive selection 4262875
32966418 32966441 19 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.26354654970800373 [3] [3,1] -5 hSpCas9 positive selection 4327147
32948350 32948373 19 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2434212963629489 [3] [3,2] 5 hSpCas9 positive selection 4327148
32948343 32948366 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.335517117820428 [3] [3,3] 6 hSpCas9 positive selection 4327149
32931471 32931493 19 + 27760321 OCIAML3 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.47494950338523556 [141,120] [138,146] 5 hSpCas9 negative selection 4388717
32933454 32933476 19 - 27760321 OCIAML3 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.28963509493962325 [574,427] [479,468] 3 hSpCas9 negative selection 4388718
32953686 32953708 19 - 27760321 OCIAML3 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.009060740549848345 [381,318] [206,362] 0 hSpCas9 negative selection 4388719
32960020 32960042 19 + 27760321 OCIAML3 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.015441490345246223 [308,244] [191,250] 0 hSpCas9 negative selection 4388720
32926946 32926968 19 + 27760321 OCIAML3 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 0.3907347750642298 [414,351] [334,465] 5 hSpCas9 negative selection 4388721
32931471 32931493 19 + 27760321 OCIAML2 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -0.381410885723968 [141,120] [64,102] -4 hSpCas9 negative selection 4472180
32933454 32933476 19 - 27760321 OCIAML2 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.17910587656822066 [574,427] [431,485] 2 hSpCas9 negative selection 4472181
32953686 32953708 19 - 27760321 OCIAML2 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 -0.26549116029263176 [381,318] [246,218] -3 hSpCas9 negative selection 4472182
32960020 32960042 19 + 27760321 OCIAML2 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.34154735848775586 [308,244] [276,288] 4 hSpCas9 negative selection 4472183
32926946 32926968 19 + 27760321 OCIAML2 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 0.13084392898127062 [414,351] [325,354] 1 hSpCas9 negative selection 4472184
32931471 32931493 19 + 27760321 MV411 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -1.7556763653671357 [141,120] [41,0] -8 hSpCas9 negative selection 4555643
32933454 32933476 19 - 27760321 MV411 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 -0.49637288800837953 [574,427] [168,327] -3 hSpCas9 negative selection 4555644
32953686 32953708 19 - 27760321 MV411 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.1734319715944852 [381,318] [226,308] 1 hSpCas9 negative selection 4555645
32960020 32960042 19 + 27760321 MV411 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.1949329934960879 [308,244] [135,315] 1 hSpCas9 negative selection 4555646
32926946 32926968 19 + 27760321 MV411 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -1.449445018698249 [414,351] [25,191] -7 hSpCas9 negative selection 4555647
32931471 32931493 19 + 27760321 HL60 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.042373445969418055 [141,120] [35,188] 0 hSpCas9 negative selection 4639106
32933454 32933476 19 - 27760321 HL60 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 -0.23704402078793882 [574,427] [279,412] -3 hSpCas9 negative selection 4639107
32953686 32953708 19 - 27760321 HL60 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.39636053193169285 [381,318] [434,311] 5 hSpCas9 negative selection 4639108
32960020 32960042 19 + 27760321 HL60 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.5845731749078875 [308,244] [244,434] 7 hSpCas9 negative selection 4639109
32926946 32926968 19 + 27760321 HL60 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 0.1122617756930019 [414,351] [368,303] 1 hSpCas9 negative selection 4639110
32931471 32931493 19 + 27760321 HT1080 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.5118439392721965 [120,94] [26,98] 2 hSpCas9 negative selection 4722569
32933454 32933476 19 - 27760321 HT1080 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 -1.2477061561321605 [427,333] [19,111] -5 hSpCas9 negative selection 4722570
32953686 32953708 19 - 27760321 HT1080 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 -0.8596602145706715 [318,248] [16,111] -4 hSpCas9 negative selection 4722571
32960020 32960042 19 + 27760321 HT1080 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 -0.6090540470371792 [244,190] [44,69] -3 hSpCas9 negative selection 4722572
32926946 32926968 19 + 27760321 HT1080 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.2965125652676623 [351,274] [168,27] -1 hSpCas9 negative selection 4722573
32931471 32931493 19 + 27760321 HT29 viability after 7 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.052747593025253225 [120,94] [261,142,46] 0 hSpCas9 negative selection 4806032
32933454 32933476 19 - 27760321 HT29 viability after 7 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.37175667781768906 [427,333] [790,561,571] 5 hSpCas9 negative selection 4806033
32953686 32953708 19 - 27760321 HT29 viability after 7 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.5265788062552795 [318,248] [457,534,572] 7 hSpCas9 negative selection 4806034
32960020 32960042 19 + 27760321 HT29 viability after 7 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 -0.30758815603851564 [244,190] [265,170,246] -4 hSpCas9 negative selection 4806035
32926946 32926968 19 + 27760321 HT29 viability after 7 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 0.1249962368679602 [351,274] [387,395,523] 2 hSpCas9 negative selection 4806036
32931471 32931493 19 + 27760321 HT29 viability after 25 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.11729896893667591 [120,94] [186,87,121] 1 hSpCas9 negative selection 4889495
32933454 32933476 19 - 27760321 HT29 viability after 25 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 -0.07399623621378558 [427,333] [352,400,498] -1 hSpCas9 negative selection 4889496
32953686 32953708 19 - 27760321 HT29 viability after 25 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 -0.15149737143706105 [318,248] [119,500,262] -1 hSpCas9 negative selection 4889497
32960020 32960042 19 + 27760321 HT29 viability after 25 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.15761664980824208 [244,190] [245,295,294] 1 hSpCas9 negative selection 4889498
32926946 32926968 19 + 27760321 HT29 viability after 25 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.2593148692574875 [351,274] [216,263,435] -3 hSpCas9 negative selection 4889499
32931471 32931493 19 + 27760321 HT29 viability after 22 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -0.6423182982628386 [120,94] [40,131,67] -5 hSpCas9 negative selection 4972958
32933454 32933476 19 - 27760321 HT29 viability after 22 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.08777450189982723 [427,333] [438,289,677] 0 hSpCas9 negative selection 4972959
32953686 32953708 19 - 27760321 HT29 viability after 22 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 -0.1732994252403358 [318,248] [224,280,369] -2 hSpCas9 negative selection 4972960
32960020 32960042 19 + 27760321 HT29 viability after 22 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.29663109605123983 [244,190] [434,198,290] 3 hSpCas9 negative selection 4972961
32926946 32926968 19 + 27760321 HT29 viability after 22 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.697507413232038 [351,274] [336,149,179] -5 hSpCas9 negative selection 4972962
32931471 32931493 19 + 27760321 HT29 viability after 19 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.3656477133916278 [120,94] [79,250,138] 3 hSpCas9 negative selection 5056421
32933454 32933476 19 - 27760321 HT29 viability after 19 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.3821624115496401 [427,333] [563,171,951] 3 hSpCas9 negative selection 5056422
32953686 32953708 19 - 27760321 HT29 viability after 19 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.29023105154048867 [318,248] [624,242,348] 2 hSpCas9 negative selection 5056423
32960020 32960042 19 + 27760321 HT29 viability after 19 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.047129044079079696 [244,190] [272,184,313] 0 hSpCas9 negative selection 5056424
32926946 32926968 19 + 27760321 HT29 viability after 19 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.5379286188478225 [351,274] [401,269,90] -5 hSpCas9 negative selection 5056425
32931471 32931493 19 + 27760321 HT29 viability after 16 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -0.6013427055953431 [120,94] [8,168,51] -5 hSpCas9 negative selection 5139884
32933454 32933476 19 - 27760321 HT29 viability after 16 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.4347753729846664 [427,333] [507,422,794] 5 hSpCas9 negative selection 5139885
32953686 32953708 19 - 27760321 HT29 viability after 16 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 -0.21813364651982203 [318,248] [372,305,148] -2 hSpCas9 negative selection 5139886
32960020 32960042 19 + 27760321 HT29 viability after 16 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.48473747334061157 [244,190] [417,379,231] 5 hSpCas9 negative selection 5139887
32926946 32926968 19 + 27760321 HT29 viability after 16 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.15607921871622737 [351,274] [271,134,537] -2 hSpCas9 negative selection 5139888
32931471 32931493 19 + 27760321 HT29 viability after 13 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -1.3011618675717183 [120,94] [25,81,44] -8 hSpCas9 negative selection 5223347
32933454 32933476 19 - 27760321 HT29 viability after 13 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.2744757925795109 [427,333] [485,397,708] 3 hSpCas9 negative selection 5223348
32953686 32953708 19 - 27760321 HT29 viability after 13 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.16204636004811832 [318,248] [260,559,289] 2 hSpCas9 negative selection 5223349
32960020 32960042 19 + 27760321 HT29 viability after 13 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.322349375123643 [244,190] [390,234,321] 4 hSpCas9 negative selection 5223350
32926946 32926968 19 + 27760321 HT29 viability after 13 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.24158304020223137 [351,274] [319,212,384] -3 hSpCas9 negative selection 5223351
32931471 32931493 19 + 27760321 HT29 viability after 10 days GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 -0.5584302021902909 [120,94] [102,130,42] -6 hSpCas9 negative selection 5306810
32933454 32933476 19 - 27760321 HT29 viability after 10 days GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 0.35636468226523377 [427,333] [469,613,739] 5 hSpCas9 negative selection 5306811
32953686 32953708 19 - 27760321 HT29 viability after 10 days TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.39174143648655235 [318,248] [408,538,449] 5 hSpCas9 negative selection 5306812
32960020 32960042 19 + 27760321 HT29 viability after 10 days GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 0.5755227347847752 [244,190] [359,371,481] 7 hSpCas9 negative selection 5306813
32926946 32926968 19 + 27760321 HT29 viability after 10 days TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 -0.03001247318284117 [351,274] [339,480,332] 0 hSpCas9 negative selection 5306814
32931471 32931493 19 + 27760321 MOLM13 viability GAGTTCTACATTCAAACGATGG CEP89 ENSG00000121289 0.5385490110626763 [141,120] [0,197] 4 hSpCas9 negative selection 5390273
32933454 32933476 19 - 27760321 MOLM13 viability GCTGAGAAGGCGTCGTCACAGG CEP89 ENSG00000121289 -0.3849593401226359 [574,427] [136,280] -3 hSpCas9 negative selection 5390274
32953686 32953708 19 - 27760321 MOLM13 viability TCATCCAGCGGCAAGGAATTGG CEP89 ENSG00000121289 0.4509641505722346 [381,318] [373,179] 3 hSpCas9 negative selection 5390275
32960020 32960042 19 + 27760321 MOLM13 viability GTCAATGTTGTCGCCAGAATGG CEP89 ENSG00000121289 -2.304609652246544 [308,244] [38,24] -8 hSpCas9 negative selection 5390276
32926946 32926968 19 + 27760321 MOLM13 viability TATAGGGCCCTTGGATGGGAGG CEP89 ENSG00000121289 0.12592946948433165 [414,351] [143,312] 0 hSpCas9 negative selection 5390277
32971879 32971902 19 + 27661255 K562 viability GCAGCGCGAGGAGAATGGACCGG CEP89 ENSG00000121289 0.21497987773494556 [795,789] [811,669] 7 dCas9-KRAB negative selection 5470391
32971933 32971956 19 - 27661255 K562 viability GGGCTTTAGGGAGTGGTCCCTGG CEP89 ENSG00000121289 0.02322136846790296 [516,792] [538,517] 0 dCas9-KRAB negative selection 5470392
32953681 32953704 19 + 27260156 BXPC3 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5665490483758914 [580] [953,822,782,1046] 9 hSpCas9 negative selection 5535333
32953632 32953655 19 + 27260156 BXPC3 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.06650477282637557 [900] [998,609,762,1269] -1 hSpCas9 negative selection 5535334
32966427 32966450 19 + 27260156 BXPC3 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7028257248562921 [224] [311,337,431,468] 9 hSpCas9 negative selection 5535335
32966418 32966441 19 - 27260156 BXPC3 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.03315084220181208 [762] [684,694,773,1001] 0 hSpCas9 negative selection 5599607
32948350 32948373 19 - 27260156 BXPC3 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.29838345653514897 [564] [751,643,812,690] 6 hSpCas9 negative selection 5599608
32948343 32948366 19 + 27260156 BXPC3 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.2534731851460006 [846] [1004,1110,1113,978] 5 hSpCas9 negative selection 5599609
32953681 32953704 19 + 27260156 A673 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4786902075567444 [580] [1173,807,919,1014] 9 hSpCas9 negative selection 5656584
32953632 32953655 19 + 27260156 A673 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.14253627752217213 [900] [1005,990,1022,895] -4 hSpCas9 negative selection 5656585
32966427 32966450 19 + 27260156 A673 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7172381955774284 [224] [496,367,467,450] 9 hSpCas9 negative selection 5656586
32966418 32966441 19 - 27260156 A673 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.026544317676960083 [762] [944,966,810,875] 0 hSpCas9 negative selection 5720858
32948350 32948373 19 - 27260156 A673 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.16143110516074044 [564] [806,735,792,699] 4 hSpCas9 negative selection 5720859
32948343 32948366 19 + 27260156 A673 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.07574922728262556 [846] [1056,1015,1027,1190] 1 hSpCas9 negative selection 5720860
32953681 32953704 19 + 27260156 A375 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.45979903256897925 [580] [767,1220,943,845] 6 hSpCas9 negative selection 5777835
32953632 32953655 19 + 27260156 A375 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.8872631678976866 [900] [547,523,633,561] -8 hSpCas9 negative selection 5777836
32966427 32966450 19 + 27260156 A375 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8887326454259051 [224] [630,577,343,413] 9 hSpCas9 negative selection 5777837
32966418 32966441 19 - 27260156 A375 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.3081389164562777 [762] [588,943,583,781] -4 hSpCas9 negative selection 5842109
32948350 32948373 19 - 27260156 A375 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.4342572952933762 [564] [1036,1018,781,759] 6 hSpCas9 negative selection 5842110
32948343 32948366 19 + 27260156 A375 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.06697720048927769 [846] [950,881,984,946] -1 hSpCas9 negative selection 5842111
32953681 32953704 19 + 27260156 COLO741 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.3899054406691147 [580] [1173,958,811] 7 hSpCas9 negative selection 5899086
32953632 32953655 19 + 27260156 COLO741 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.04319262541701785 [900] [1348,1153,1074] 0 hSpCas9 negative selection 5899087
32966427 32966450 19 + 27260156 COLO741 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8878015836050447 [224] [468,651,472] 9 hSpCas9 negative selection 5899088
32966418 32966441 19 - 27260156 COLO741 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.10432332667135924 [762] [1056,1045,1039] 2 hSpCas9 negative selection 5963360
32948350 32948373 19 - 27260156 COLO741 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.35831910290153857 [564] [1007,846,925] 7 hSpCas9 negative selection 5963361
32948343 32948366 19 + 27260156 COLO741 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.23611957970660513 [846] [1554,1121,1174] 5 hSpCas9 negative selection 5963362
32953681 32953704 19 + 27260156 CAL120 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4520734898797074 [580] [800,1178,958] 6 hSpCas9 negative selection 6020337
32953632 32953655 19 + 27260156 CAL120 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.16337187436205014 [900] [1685,1162,986] 2 hSpCas9 negative selection 6020338
32966427 32966450 19 + 27260156 CAL120 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7904388982875719 [224] [353,538,538] 9 hSpCas9 negative selection 6020339
32966418 32966441 19 - 27260156 CAL120 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.22853290765357942 [762] [826,835,770] -3 hSpCas9 negative selection 6084611
32948350 32948373 19 - 27260156 CAL120 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.11441192051046728 [564] [667,951,650] 1 hSpCas9 negative selection 6084612
32948343 32948366 19 + 27260156 CAL120 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.5939777181573744 [846] [1888,1062,1859] 8 hSpCas9 negative selection 6084613
32953681 32953704 19 + 27260156 CADOES1 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5595971606964932 [580] [707,876,678,926] 8 hSpCas9 negative selection 6141588
32953632 32953655 19 + 27260156 CADOES1 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.1537720793698122 [900] [854,805,825,516] -3 hSpCas9 negative selection 6141589
32966427 32966450 19 + 27260156 CADOES1 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7783786722039089 [224] [323,280,359,474] 9 hSpCas9 negative selection 6141590
32966418 32966441 19 - 27260156 CADOES1 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.296716799826119 [762] [556,486,553,717] -5 hSpCas9 negative selection 6205862
32948350 32948373 19 - 27260156 CADOES1 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2512008112513432 [564] [601,585,679,633] 4 hSpCas9 negative selection 6205863
32948343 32948366 19 + 27260156 CADOES1 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.1807127135062081 [846] [1016,812,823,917] 3 hSpCas9 negative selection 6205864
32953681 32953704 19 + 27260156 EWS502 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.6586889736870868 [580] [772,900,1077,1172] 9 hSpCas9 negative selection 6262839
32953632 32953655 19 + 27260156 EWS502 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.1520049237544715 [900] [806,907,983,729] -3 hSpCas9 negative selection 6262840
32966427 32966450 19 + 27260156 EWS502 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7226562204361775 [224] [243,281,472,611] 9 hSpCas9 negative selection 6262841
32966418 32966441 19 - 27260156 EWS502 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.16946831154661435 [762] [741,796,717,599] -3 hSpCas9 negative selection 6327113
32948350 32948373 19 - 27260156 EWS502 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.09573970337349624 [564] [607,738,555,651] 1 hSpCas9 negative selection 6327114
32948343 32948366 19 + 27260156 EWS502 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.01619152015925529 [846] [719,796,1005,1059] 0 hSpCas9 negative selection 6327115
32953681 32953704 19 + 27260156 EW8 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4503002826266266 [580] [630,540,500,919] 7 hSpCas9 negative selection 6384090
32953632 32953655 19 + 27260156 EW8 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.6209947393915136 [900] [651,511,432,327] -8 hSpCas9 negative selection 6384091
32966427 32966450 19 + 27260156 EW8 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 -0.07613029818137185 [224] [245,243,95,126] -1 hSpCas9 negative selection 6384092
32966418 32966441 19 - 27260156 EW8 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.667081874733068 [762] [660,352,304,281] -8 hSpCas9 negative selection 6448364
32948350 32948373 19 - 27260156 EW8 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.07800183348080936 [564] [486,373,485,583] 1 hSpCas9 negative selection 6448365
32948343 32948366 19 + 27260156 EW8 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.1599854796853436 [846] [684,951,417,443] -3 hSpCas9 negative selection 6448366
32953681 32953704 19 + 27260156 CORL105 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.3369738183459865 [580] [882,625,810,1112] 6 hSpCas9 negative selection 6505341
32953632 32953655 19 + 27260156 CORL105 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.45496294577562724 [900] [932,794,771,583] -7 hSpCas9 negative selection 6505342
32966427 32966450 19 + 27260156 CORL105 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.5608604773967449 [224] [410,343,471,341] 8 hSpCas9 negative selection 6505343
32966418 32966441 19 - 27260156 CORL105 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.6173896849260601 [762] [532,487,579,726] -8 hSpCas9 negative selection 6569615
32948350 32948373 19 - 27260156 CORL105 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.24843446178820283 [564] [864,682,983,646] 4 hSpCas9 negative selection 6569616
32948343 32948366 19 + 27260156 CORL105 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.16974109590865982 [846] [847,866,864,941] -3 hSpCas9 negative selection 6569617
32953681 32953704 19 + 27260156 HS294T viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.7152388841300265 [580] [313,461,296,409] 8 hSpCas9 negative selection 6626592
32953632 32953655 19 + 27260156 HS294T viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.19383355525675083 [900] [211,329,295,403] -3 hSpCas9 negative selection 6626593
32966427 32966450 19 + 27260156 HS294T viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.6471034331432268 [224] [111,130,152,153] 8 hSpCas9 negative selection 6626594
32966418 32966441 19 - 27260156 HS294T viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.2515231403917057 [762] [281,231,253,213] -4 hSpCas9 negative selection 6690866
32948350 32948373 19 - 27260156 HS294T viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.3971513694349619 [564] [275,199,349,335] 5 hSpCas9 negative selection 6690867
32948343 32948366 19 + 27260156 HS294T viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.39487507246348397 [846] [246,185,284,285] -5 hSpCas9 negative selection 6690868
32953681 32953704 19 + 27260156 HCC44 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.3538371088874117 [580] [961,603,889,945] 6 hSpCas9 negative selection 6747843
32953632 32953655 19 + 27260156 HCC44 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.30039745024726183 [900] [1082,1065,1586,1338] 5 hSpCas9 negative selection 6747844
32966427 32966450 19 + 27260156 HCC44 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 1.0777159777118304 [224] [591,409,545,617] 9 hSpCas9 negative selection 6747845
32966418 32966441 19 - 27260156 HCC44 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.2311214592969505 [762] [1283,666,963,1187] 4 hSpCas9 negative selection 6812117
32948350 32948373 19 - 27260156 HCC44 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.4963448023897574 [564] [1148,696,1327,560] 7 hSpCas9 negative selection 6812118
32948343 32948366 19 + 27260156 HCC44 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.4471035620351973 [846] [1632,1008,1554,1136] 7 hSpCas9 negative selection 6812119
32953681 32953704 19 + 27260156 G402 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.2455520496077519 [580] [1135,1011,776,502] 3 hSpCas9 negative selection 6869094
32953632 32953655 19 + 27260156 G402 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.4120444757488897 [900] [845,1002,915,562] -5 hSpCas9 negative selection 6869095
32966427 32966450 19 + 27260156 G402 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.5545453574792293 [224] [396,463,307,442] 7 hSpCas9 negative selection 6869096
32966418 32966441 19 - 27260156 G402 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.012176956309063347 [762] [1258,829,893,814] 0 hSpCas9 negative selection 6933368
32948350 32948373 19 - 27260156 G402 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 -0.01031184136544272 [564] [1121,481,799,396] 0 hSpCas9 negative selection 6933369
32948343 32948366 19 + 27260156 G402 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.09075078142476356 [846] [1339,1752,1110,305] 1 hSpCas9 negative selection 6933370
32953681 32953704 19 + 27260156 L33 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.494964008520256 [580] [772,398,530,685] 8 hSpCas9 negative selection 6990345
32953632 32953655 19 + 27260156 L33 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.24046575095267453 [900] [1144,399,608,1163] 5 hSpCas9 negative selection 6990346
32966427 32966450 19 + 27260156 L33 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7144730831628141 [224] [339,174,246,317] 9 hSpCas9 negative selection 6990347
32966418 32966441 19 - 27260156 L33 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.038593533877011366 [762] [736,356,449,810] 0 hSpCas9 negative selection 7054619
32948350 32948373 19 - 27260156 L33 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.18071429228879088 [564] [699,279,380,570] 4 hSpCas9 negative selection 7054620
32948343 32948366 19 + 27260156 L33 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.21381979499984127 [846] [849,399,597,1152] 4 hSpCas9 negative selection 7054621
32953681 32953704 19 + 27260156 K562 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.79057990040795 [580] [1257,950,724,686] 8 hSpCas9 negative selection 7111596
32953632 32953655 19 + 27260156 K562 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.27818897495110273 [900] [565,618,819,623] -3 hSpCas9 negative selection 7111597
32966427 32966450 19 + 27260156 K562 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.920148208217134 [224] [717,218,362,244] 9 hSpCas9 negative selection 7111598
32966418 32966441 19 - 27260156 K562 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.24247764473300243 [762] [650,310,936,400] -3 hSpCas9 negative selection 7175870
32948350 32948373 19 - 27260156 K562 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.417219353298385 [564] [1009,480,699,519] 5 hSpCas9 negative selection 7175871
32948343 32948366 19 + 27260156 K562 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.053645183843375466 [846] [914,671,579,737] 0 hSpCas9 negative selection 7175872
32953681 32953704 19 + 27260156 HT29 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5587082964306532 [580] [1171,1288,1068,697] 9 hSpCas9 negative selection 7232847
32953632 32953655 19 + 27260156 HT29 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.13677387914556494 [900] [967,1028,1117,877] -3 hSpCas9 negative selection 7232848
32966427 32966450 19 + 27260156 HT29 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7934191780528883 [224] [552,427,521,400] 9 hSpCas9 negative selection 7232849
32966418 32966441 19 - 27260156 HT29 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.16275141265916648 [762] [902,843,880,702] -3 hSpCas9 negative selection 7297121
32948350 32948373 19 - 27260156 HT29 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.11276144020538298 [564] [830,804,801,561] 2 hSpCas9 negative selection 7297122
32948343 32948366 19 + 27260156 HT29 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.13342429218628904 [846] [920,1076,1015,765] -3 hSpCas9 negative selection 7297123
32953681 32953704 19 + 27260156 MHHES1 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.6222469857063789 [580] [917,1102,1202,824] 9 hSpCas9 negative selection 7354098
32953632 32953655 19 + 27260156 MHHES1 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.06816438705390626 [900] [1179,865,1139,734] -1 hSpCas9 negative selection 7354099
32966427 32966450 19 + 27260156 MHHES1 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7397287947471687 [224] [464,437,514,300] 9 hSpCas9 negative selection 7354100
32966418 32966441 19 - 27260156 MHHES1 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.070090436914797 [762] [787,1022,797,692] -1 hSpCas9 negative selection 7418372
32948350 32948373 19 - 27260156 MHHES1 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.4016222261505491 [564] [1166,915,805,565] 7 hSpCas9 negative selection 7418373
32948343 32948366 19 + 27260156 MHHES1 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.1779032227438384 [846] [1102,1162,1189,891] 3 hSpCas9 negative selection 7418374
32953681 32953704 19 + 27260156 MEWO viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5038096955824286 [580] [973,655,721] 8 hSpCas9 negative selection 7475349
32953632 32953655 19 + 27260156 MEWO viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.3463205146882702 [900] [778,551,680] -6 hSpCas9 negative selection 7475350
32966427 32966450 19 + 27260156 MEWO viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.9912546182673025 [224] [428,484,342] 9 hSpCas9 negative selection 7475351
32966418 32966441 19 - 27260156 MEWO viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.1902895437408868 [762] [785,585,535] -4 hSpCas9 negative selection 7539623
32948350 32948373 19 - 27260156 MEWO viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.20538069109375567 [564] [659,617,559] 4 hSpCas9 negative selection 7539624
32948343 32948366 19 + 27260156 MEWO viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.16630468324656822 [846] [644,793,666] -4 hSpCas9 negative selection 7539625
32953681 32953704 19 + 27260156 LNCAPCLONEFGC viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.6048042351699497 [580] [599,778,831,999] 8 hSpCas9 negative selection 7596600
32953632 32953655 19 + 27260156 LNCAPCLONEFGC viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.1802249152294242 [900] [615,860,655,730] -3 hSpCas9 negative selection 7596601
32966427 32966450 19 + 27260156 LNCAPCLONEFGC viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7776458843719298 [224] [378,367,432,227] 9 hSpCas9 negative selection 7596602
32966418 32966441 19 - 27260156 LNCAPCLONEFGC viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.45976859143889776 [762] [416,614,501,469] -6 hSpCas9 negative selection 7660874
32948350 32948373 19 - 27260156 LNCAPCLONEFGC viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.27613339516771385 [564] [525,794,606,538] 4 hSpCas9 negative selection 7660875
32948343 32948366 19 + 27260156 LNCAPCLONEFGC viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.015135008873098599 [846] [895,623,919,689] 0 hSpCas9 negative selection 7660876
32953681 32953704 19 + 27260156 PANC0327 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.2834969944057575 [580] [530,388,974,640] 4 hSpCas9 negative selection 7717851
32953632 32953655 19 + 27260156 PANC0327 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.22070698788083198 [900] [845,453,626,862] -3 hSpCas9 negative selection 7717852
32966427 32966450 19 + 27260156 PANC0327 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.831606096857494 [224] [321,439,316,329] 9 hSpCas9 negative selection 7717853
32966418 32966441 19 - 27260156 PANC0327 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -1.1159099310734892 [762] [287,319,380,258] -8 hSpCas9 negative selection 7782125
32948350 32948373 19 - 27260156 PANC0327 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.06877873467365281 [564] [519,229,544,847] 1 hSpCas9 negative selection 7782126
32948343 32948366 19 + 27260156 PANC0327 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.24087235545537522 [846] [813,783,482,460] -4 hSpCas9 negative selection 7782127
32953681 32953704 19 + 27260156 NCIH2009 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.7196890694022974 [580] [1613,1443,1002] 8 hSpCas9 negative selection 7839102
32953632 32953655 19 + 27260156 NCIH2009 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.14351879144537583 [900] [986,1183,1214] -2 hSpCas9 negative selection 7839103
32966427 32966450 19 + 27260156 NCIH2009 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 1.288908542438381 [224] [510,1000,735] 9 hSpCas9 negative selection 7839104
32966418 32966441 19 - 27260156 NCIH2009 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 0.1928180568768969 [762] [1405,964,1323] 2 hSpCas9 negative selection 7903376
32948350 32948373 19 - 27260156 NCIH2009 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 -0.0007918166403804716 [564] [905,715,767] 0 hSpCas9 negative selection 7903377
32948343 32948366 19 + 27260156 NCIH2009 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.11844651532475958 [846] [1560,1250,1094] 1 hSpCas9 negative selection 7903378
32953681 32953704 19 + 27260156 NCIH1373 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4721222445009995 [580] [641,840,864,327] 4 hSpCas9 negative selection 7960353
32953632 32953655 19 + 27260156 NCIH1373 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.04681854065640956 [900] [1105,1043,1003,196] 0 hSpCas9 negative selection 7960354
32966427 32966450 19 + 27260156 NCIH1373 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8563062558447293 [224] [595,362,639,62] 8 hSpCas9 negative selection 7960355
32966418 32966441 19 - 27260156 NCIH1373 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.48099397441680497 [762] [1105,522,372,139] -5 hSpCas9 negative selection 8024627
32948350 32948373 19 - 27260156 NCIH1373 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2886687678464174 [564] [765,410,1278,171] 3 hSpCas9 negative selection 8024628
32948343 32948366 19 + 27260156 NCIH1373 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.6573540652115156 [846] [1163,304,383,178] -6 hSpCas9 negative selection 8024629
32953681 32953704 19 + 27260156 PATU8902 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.112274198086937 [580] [1061,802,618,1097] 1 hSpCas9 negative selection 8081604
32953632 32953655 19 + 27260156 PATU8902 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.7518788553675366 [900] [855,992,696,398] -6 hSpCas9 negative selection 8081605
32966427 32966450 19 + 27260156 PATU8902 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.9953069762555183 [224] [699,617,655,494] 9 hSpCas9 negative selection 8081606
32966418 32966441 19 - 27260156 PATU8902 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.390912242353882 [762] [753,1019,552,998] -4 hSpCas9 negative selection 8145878
32948350 32948373 19 - 27260156 PATU8902 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.07459757944464335 [564] [854,741,766,976] 0 hSpCas9 negative selection 8145879
32948343 32948366 19 + 27260156 PATU8902 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.209236801596423 [846] [1031,1098,676,1399] -2 hSpCas9 negative selection 8145880
32953681 32953704 19 + 27260156 PANC1 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5682933699550801 [580] [658,884,631,792] 8 hSpCas9 negative selection 8202855
32953632 32953655 19 + 27260156 PANC1 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.20160855583283843 [900] [708,796,756,475] -3 hSpCas9 negative selection 8202856
32966427 32966450 19 + 27260156 PANC1 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.37462887991079163 [224] [149,401,187,284] 6 hSpCas9 negative selection 8202857
32966418 32966441 19 - 27260156 PANC1 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.32811465450701566 [762] [451,427,556,609] -5 hSpCas9 negative selection 8267129
32948350 32948373 19 - 27260156 PANC1 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.46785627617114744 [564] [554,1006,499,679] 7 hSpCas9 negative selection 8267130
32948343 32948366 19 + 27260156 PANC1 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.10605878505350108 [846] [657,728,677,643] -2 hSpCas9 negative selection 8267131
32953681 32953704 19 + 27260156 PANC0813 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5742915738889955 [580] [998,1293,1112,674] 8 hSpCas9 negative selection 8324106
32953632 32953655 19 + 27260156 PANC0813 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.10940545172352556 [900] [1080,1386,1045,1049] 1 hSpCas9 negative selection 8324107
32966427 32966450 19 + 27260156 PANC0813 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.6847118713527663 [224] [475,479,239,501] 9 hSpCas9 negative selection 8324108
32966418 32966441 19 - 27260156 PANC0813 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.07573766004236837 [762] [985,965,822,648] -1 hSpCas9 negative selection 8388380
32948350 32948373 19 - 27260156 PANC0813 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2321198274228548 [564] [803,905,675,734] 4 hSpCas9 negative selection 8388381
32948343 32948366 19 + 27260156 PANC0813 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.012916966151243381 [846] [918,1028,977,1008] 0 hSpCas9 negative selection 8388382
32953681 32953704 19 + 27260156 RDES viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.6883791426578701 [580] [924,889,1224,1328] 9 hSpCas9 negative selection 8445357
32953632 32953655 19 + 27260156 RDES viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.22309741589807686 [900] [776,729,925,1174] -4 hSpCas9 negative selection 8445358
32966427 32966450 19 + 27260156 RDES viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8040053702746282 [224] [386,389,459,598] 9 hSpCas9 negative selection 8445359
32966418 32966441 19 - 27260156 RDES viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.23988433802806952 [762] [654,756,676,897] -4 hSpCas9 negative selection 8509631
32948350 32948373 19 - 27260156 RDES viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.23688714551477408 [564] [625,639,794,1068] 4 hSpCas9 negative selection 8509632
32948343 32948366 19 + 27260156 RDES viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.04049076094465054 [846] [857,896,1039,997] 0 hSpCas9 negative selection 8509633
32953681 32953704 19 + 27260156 PC3 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.47852187728669493 [580] [351,680,1847,907] 8 hSpCas9 negative selection 8566608
32953632 32953655 19 + 27260156 PC3 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.379825867933102 [900] [352,594,1341,828] -7 hSpCas9 negative selection 8566609
32966427 32966450 19 + 27260156 PC3 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8305827579880878 [224] [208,393,680,474] 9 hSpCas9 negative selection 8566610
32966418 32966441 19 - 27260156 PC3 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.03576537300874494 [762] [387,818,1352,733] -1 hSpCas9 negative selection 8630882
32948350 32948373 19 - 27260156 PC3 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2281900573968355 [564] [402,652,1090,711] 5 hSpCas9 negative selection 8630883
32948343 32948366 19 + 27260156 PC3 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.010690438735999286 [846] [537,885,1452,808] 0 hSpCas9 negative selection 8630884
32953681 32953704 19 + 27260156 PATU8988T viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5228913941180495 [580] [976,876,656,716] 8 hSpCas9 negative selection 8687859
32953632 32953655 19 + 27260156 PATU8988T viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.32890257088228203 [900] [652,981,469,697] -5 hSpCas9 negative selection 8687860
32966427 32966450 19 + 27260156 PATU8988T viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7898985374898111 [224] [237,419,416,436] 9 hSpCas9 negative selection 8687861
32966418 32966441 19 - 27260156 PATU8988T viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.7164474555488387 [762] [452,383,491,459] -8 hSpCas9 negative selection 8752133
32948350 32948373 19 - 27260156 PATU8988T viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.04148999226282446 [564] [561,607,386,708] 0 hSpCas9 negative selection 8752134
32948343 32948366 19 + 27260156 PATU8988T viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.05005341602266644 [846] [725,790,669,992] -1 hSpCas9 negative selection 8752135
32953681 32953704 19 + 27260156 T47D viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.561697253039599 [580] [1125,824,929,1135] 9 hSpCas9 negative selection 8809110
32953632 32953655 19 + 27260156 T47D viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.23600201374264007 [900] [943,877,846,897] -5 hSpCas9 negative selection 8809111
32966427 32966450 19 + 27260156 T47D viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7080122179994394 [224] [371,433,417,489] 9 hSpCas9 negative selection 8809112
32966418 32966441 19 - 27260156 T47D viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.046312043293598726 [762] [830,686,883,1061] -1 hSpCas9 negative selection 8873384
32948350 32948373 19 - 27260156 T47D viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.313081946553148 [564] [928,802,762,776] 6 hSpCas9 negative selection 8873385
32948343 32948366 19 + 27260156 T47D viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.0966776410159692 [846] [1117,919,1074,1120] 2 hSpCas9 negative selection 8873386
32953681 32953704 19 + 27260156 SU8686 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.3254522744941899 [580] [556,727,839,788] 5 hSpCas9 negative selection 8930361
32953632 32953655 19 + 27260156 SU8686 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.16923978944091267 [900] [889,798,1113,1297] 3 hSpCas9 negative selection 8930362
32966427 32966450 19 + 27260156 SU8686 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.8379298692097287 [224] [330,366,453,463] 9 hSpCas9 negative selection 8930363
32966418 32966441 19 - 27260156 SU8686 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.12844336455735694 [762] [568,660,700,880] -2 hSpCas9 negative selection 8994635
32948350 32948373 19 - 27260156 SU8686 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.17087345887595173 [564] [600,561,670,709] 3 hSpCas9 negative selection 8994636
32948343 32948366 19 + 27260156 SU8686 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 -0.19463891685736112 [846] [602,647,843,888] -3 hSpCas9 negative selection 8994637
32953681 32953704 19 + 27260156 SKES1 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5029542771371885 [580] [1093,895,750,608] 8 hSpCas9 negative selection 9051612
32953632 32953655 19 + 27260156 SKES1 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.2402163468952343 [900] [907,906,718,563] -5 hSpCas9 negative selection 9051613
32966427 32966450 19 + 27260156 SKES1 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.7146521055932644 [224] [384,471,315,317] 9 hSpCas9 negative selection 9051614
32966418 32966441 19 - 27260156 SKES1 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.08589586137265304 [762] [827,780,673,613] -2 hSpCas9 negative selection 9115886
32948350 32948373 19 - 27260156 SKES1 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.05816416524203305 [564] [602,663,586,507] 1 hSpCas9 negative selection 9115887
32948343 32948366 19 + 27260156 SKES1 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.030993390130683918 [846] [1029,1116,611,754] 0 hSpCas9 negative selection 9115888
32953681 32953704 19 + 27260156 TOV112D viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4345907423757799 [580] [972,1023,482,739] 7 hSpCas9 negative selection 9172863
32953632 32953655 19 + 27260156 TOV112D viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 0.09101320641918076 [900] [644,2120,669,673] 1 hSpCas9 negative selection 9172864
32966427 32966450 19 + 27260156 TOV112D viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.6565806238075457 [224] [275,511,191,468] 9 hSpCas9 negative selection 9172865
32966418 32966441 19 - 27260156 TOV112D viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.31996962864148976 [762] [700,653,553,557] -6 hSpCas9 negative selection 9237137
32948350 32948373 19 - 27260156 TOV112D viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.2669802116513309 [564] [703,764,625,650] 5 hSpCas9 negative selection 9237138
32948343 32948366 19 + 27260156 TOV112D viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.08321141148189903 [846] [794,1442,673,808] 1 hSpCas9 negative selection 9237139
32953681 32953704 19 + 27260156 TC71 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.4978337392111746 [580] [846,812,729,1149] 9 hSpCas9 negative selection 9294114
32953632 32953655 19 + 27260156 TC71 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.06781997050896305 [900] [812,962,918,997] -2 hSpCas9 negative selection 9294115
32966427 32966450 19 + 27260156 TC71 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.6003901713520601 [224] [401,334,319,408] 9 hSpCas9 negative selection 9294116
32966418 32966441 19 - 27260156 TC71 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.052253508354158096 [762] [782,741,755,880] -1 hSpCas9 negative selection 9358388
32948350 32948373 19 - 27260156 TC71 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.14407545559016194 [564] [733,548,619,780] 3 hSpCas9 negative selection 9358389
32948343 32948366 19 + 27260156 TC71 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.14764272954999025 [846] [984,916,912,1224] 4 hSpCas9 negative selection 9358390
32953681 32953704 19 + 27260156 TC32 viability ATCCCCCAATTCCTTGCCGCTGG CEP89 ENSG00000121289 0.5246401814788538 [580] [795,709,965,670] 8 hSpCas9 negative selection 9415365
32953632 32953655 19 + 27260156 TC32 viability CAGCGTACAGGTCATCACTGTGG CEP89 ENSG00000121289 -0.2977768044726976 [900] [626,408,1027,833] -5 hSpCas9 negative selection 9415366
32966427 32966450 19 + 27260156 TC32 viability CAACGCTGGCTGCAGGTAAAAGG CEP89 ENSG00000121289 0.4752559039765133 [224] [275,206,397,332] 7 hSpCas9 negative selection 9415367
32966418 32966441 19 - 27260156 TC32 viability TGCAGCCAGCGTTGCTCCGAAGG CEP89 ENSG00000121289 -0.2832127402319416 [762] [454,531,765,639] -5 hSpCas9 negative selection 9479639
32948350 32948373 19 - 27260156 TC32 viability AAAGGTGCCATTGTTACATGAGG CEP89 ENSG00000121289 0.32920037879410513 [564] [626,474,980,678] 6 hSpCas9 negative selection 9479640
32948343 32948366 19 + 27260156 TC32 viability CTGTTCACCTCATGTAACAATGG CEP89 ENSG00000121289 0.08923277705000321 [846] [924,695,879,886] 1 hSpCas9 negative selection 9479641
32918223 32918246 19 - 27869803 HPAFII viability after 27 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.8926043161327286 [500] [362,593,NaN] 7 hSpCas9 negative selection 9566990
32926953 32926976 19 - 27869803 HPAFII viability after 27 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.9171413201463856 [79] [12,29,NaN] -6 hSpCas9 negative selection 9566991
32933447 32933470 19 - 27869803 HPAFII viability after 27 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.4692061425214486 [340] [77,389,NaN] 4 hSpCas9 negative selection 9566992
32953692 32953715 19 - 27869803 HPAFII viability after 27 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.10895057728418178 [434] [184,297,NaN] 0 hSpCas9 negative selection 9566993
32959983 32960006 19 - 27869803 HPAFII viability after 27 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 -0.3354539514580903 [227] [172,29,NaN] -3 hSpCas9 negative selection 9566994
32966413 32966436 19 + 27869803 HPAFII viability after 27 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.0688143083273347 [108] [52,55,NaN] 0 hSpCas9 negative selection 9566995
32918223 32918246 19 - 27869803 HPAFII viability after 15 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 0.29421399721337815 [500] [769,591,NaN] 3 hSpCas9 negative selection 9649439
32926953 32926976 19 - 27869803 HPAFII viability after 15 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.1859454834019072 [79] [53,88,NaN] -2 hSpCas9 negative selection 9649440
32933447 32933470 19 - 27869803 HPAFII viability after 15 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 -0.24996352149502812 [340] [293,316,NaN] -3 hSpCas9 negative selection 9649441
32953692 32953715 19 - 27869803 HPAFII viability after 15 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.3465242848538805 [434] [371,364,NaN] -4 hSpCas9 negative selection 9649442
32959983 32960006 19 - 27869803 HPAFII viability after 15 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.28256935544832784 [227] [347,266,NaN] 3 hSpCas9 negative selection 9649443
32966413 32966436 19 + 27869803 HPAFII viability after 15 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.8386188667779968 [108] [120,30,NaN] -7 hSpCas9 negative selection 9649444
32918223 32918246 19 - 27869803 ASPC1 viability after 36 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 -0.3481877821140583 [1262] [333,405,303] -4 hSpCas9 negative selection 9731888
32926953 32926976 19 - 27869803 ASPC1 viability after 36 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.7311991545878376 [200] [51,40,35] -6 hSpCas9 negative selection 9731889
32933447 32933470 19 - 27869803 ASPC1 viability after 36 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.4866072668422036 [616] [525,281,156] 5 hSpCas9 negative selection 9731890
32953692 32953715 19 - 27869803 ASPC1 viability after 36 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.25432784313428003 [1124] [557,244,577] 2 hSpCas9 negative selection 9731891
32959983 32960006 19 - 27869803 ASPC1 viability after 36 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.4473376352738339 [534] [127,363,253] 4 hSpCas9 negative selection 9731892
32966413 32966436 19 + 27869803 ASPC1 viability after 36 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.2632381979606249 [206] [42,451,41] 9 hSpCas9 negative selection 9731893
32918223 32918246 19 - 27869803 PATU8988S viability after 35 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 -0.07360773900508621 [1100] [364,477,NaN] 0 hSpCas9 negative selection 9814337
32926953 32926976 19 - 27869803 PATU8988S viability after 35 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.7188519967377123 [185] [51,38,NaN] -6 hSpCas9 negative selection 9814338
32933447 32933470 19 - 27869803 PATU8988S viability after 35 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.5349045955080706 [539] [359,269,NaN] 6 hSpCas9 negative selection 9814339
32953692 32953715 19 - 27869803 PATU8988S viability after 35 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.3047027108897057 [947] [512,429,NaN] 3 hSpCas9 negative selection 9814340
32959983 32960006 19 - 27869803 PATU8988S viability after 35 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.37901467492199825 [568] [305,289,NaN] 4 hSpCas9 negative selection 9814341
32966413 32966436 19 + 27869803 PATU8988S viability after 35 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.6724767016040332 [213] [377,170,NaN] 9 hSpCas9 negative selection 9814342
32918223 32918246 19 - 27869803 PATU8988S viability after 31 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 -0.3248749285311301 [1100] [236,494,NaN] -4 hSpCas9 negative selection 9896786
32926953 32926976 19 - 27869803 PATU8988S viability after 31 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.46631059874796055 [185] [65,37,NaN] -5 hSpCas9 negative selection 9896787
32933447 32933470 19 - 27869803 PATU8988S viability after 31 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.3625668115314809 [539] [282,268,NaN] 4 hSpCas9 negative selection 9896788
32953692 32953715 19 - 27869803 PATU8988S viability after 31 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 0.08184999901404211 [947] [374,431,NaN] 1 hSpCas9 negative selection 9896789
32959983 32960006 19 - 27869803 PATU8988S viability after 31 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.051436916125189504 [568] [235,233,NaN] 0 hSpCas9 negative selection 9896790
32966413 32966436 19 + 27869803 PATU8988S viability after 31 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 1.558705705138655 [213] [330,149,NaN] 9 hSpCas9 negative selection 9896791
32918223 32918246 19 - 27869803 HPAFII viability after 35 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 1.5587372987109298 [500] [519,1002,NaN] 9 hSpCas9 negative selection 9979235
32926953 32926976 19 - 27869803 HPAFII viability after 35 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.17769702830324108 [79] [0,74,NaN] -1 hSpCas9 negative selection 9979236
32933447 32933470 19 - 27869803 HPAFII viability after 35 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.4707582749628018 [340] [123,368,NaN] 3 hSpCas9 negative selection 9979237
32953692 32953715 19 - 27869803 HPAFII viability after 35 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.17840927726975875 [434] [100,299,NaN] -1 hSpCas9 negative selection 9979238
32959983 32960006 19 - 27869803 HPAFII viability after 35 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.1956647519625886 [227] [158,101,NaN] 1 hSpCas9 negative selection 9979239
32966413 32966436 19 + 27869803 HPAFII viability after 35 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.9340258544694664 [108] [26,30,NaN] -5 hSpCas9 negative selection 9979240
32918223 32918246 19 - 27869803 HPAFII viability after 31 days CACCAGGAGCGCCTCCAAGAAGG CEP89 ENSG00000121289 1.245861062902134 [500] [472,877,NaN] 8 hSpCas9 negative selection 10061684
32926953 32926976 19 - 27869803 HPAFII viability after 31 days ATTGAAGGCCTCCCATCCAAGGG CEP89 ENSG00000121289 -0.5954720991286162 [79] [0,60,NaN] -4 hSpCas9 negative selection 10061685
32933447 32933470 19 - 27869803 HPAFII viability after 31 days AAGGCGTCGTCACAGGAAGGTGG CEP89 ENSG00000121289 0.43786394899364073 [340] [96,435,NaN] 3 hSpCas9 negative selection 10061686
32953692 32953715 19 - 27869803 HPAFII viability after 31 days TCAGCTGTCATCCAGCGGCAAGG CEP89 ENSG00000121289 -0.314059163979968 [434] [159,235,NaN] -2 hSpCas9 negative selection 10061687
32959983 32960006 19 - 27869803 HPAFII viability after 31 days CTATTCCTCAGCCTCGCCAGAGG CEP89 ENSG00000121289 0.2658618189566985 [227] [183,120,NaN] 2 hSpCas9 negative selection 10061688
32966413 32966436 19 + 27869803 HPAFII viability after 31 days AGCTGCCTTCGGAGCAACGCTGG CEP89 ENSG00000121289 -0.4083418319024179 [108] [36,55,NaN] -3 hSpCas9 negative selection 10061689
32966375 32966398 19 + 28162770 P31FUJ viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.4753725076884567 [167] [70] -7 hSpCas9 negative selection 10131980
32881872 32881895 19 - 28162770 P31FUJ viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.9532796757920157 [144] [43] -8 hSpCas9 negative selection 10131981
32953697 32953720 19 - 28162770 P31FUJ viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.4351103797074942 [106] [92] -4 hSpCas9 negative selection 10131982
32937642 32937665 19 + 28162770 P31FUJ viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.26998578341730045 [294] [417] 3 hSpCas9 negative selection 10131983
32931521 32931544 19 - 28162770 P31FUJ viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.08163135392605941 [192] [239] 0 hSpCas9 negative selection 10131984
32931508 32931531 19 - 28162770 P31FUJ viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.222877279361811 [34] [47] 2 hSpCas9 negative selection 10131985
32915482 32915505 19 - 28162770 P31FUJ viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.07344426824071393 [147] [182] 0 hSpCas9 negative selection 10131986
32915385 32915408 19 - 28162770 P31FUJ viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.30555854684969286 [60] [57] -3 hSpCas9 negative selection 10131987
32901279 32901302 19 - 28162770 P31FUJ viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.4511703021379433 [304] [489] 5 hSpCas9 negative selection 10131988
32881981 32882004 19 - 28162770 P31FUJ viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.2701002810765414 [421] [597] 3 hSpCas9 negative selection 10131989
32966375 32966398 19 + 28162770 TF1 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 NaN [NaN] [88] 1 hSpCas9 negative selection 10301346
32881872 32881895 19 - 28162770 TF1 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 NaN [NaN] [14] 1 hSpCas9 negative selection 10301347
32953697 32953720 19 - 28162770 TF1 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 NaN [NaN] [97] 1 hSpCas9 negative selection 10301348
32937642 32937665 19 + 28162770 TF1 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 NaN [NaN] [207] 1 hSpCas9 negative selection 10301349
32931521 32931544 19 - 28162770 TF1 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 NaN [NaN] [134] 1 hSpCas9 negative selection 10301350
32931508 32931531 19 - 28162770 TF1 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 NaN [NaN] [53] 1 hSpCas9 negative selection 10301351
32915482 32915505 19 - 28162770 TF1 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 NaN [NaN] [112] 1 hSpCas9 negative selection 10301352
32915385 32915408 19 - 28162770 TF1 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 NaN [NaN] [119] 1 hSpCas9 negative selection 10301353
32901279 32901302 19 - 28162770 TF1 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 NaN [NaN] [227] 1 hSpCas9 negative selection 10301354
32881981 32882004 19 - 28162770 TF1 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 NaN [NaN] [540] 1 hSpCas9 negative selection 10301355
32966375 32966398 19 + 28162770 SKM1 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.5256086952417807 [56] [34] -7 hSpCas9 negative selection 10470712
32881872 32881895 19 - 28162770 SKM1 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -3.0850361038557996 [23] [4] -9 hSpCas9 negative selection 10470713
32953697 32953720 19 - 28162770 SKM1 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.15597199564799558 [32] [64] 1 hSpCas9 negative selection 10470714
32937642 32937665 19 + 28162770 SKM1 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.6276089498042645 [66] [182] 6 hSpCas9 negative selection 10470715
32931521 32931544 19 - 28162770 SKM1 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 -0.06909455998677777 [53] [90] 0 hSpCas9 negative selection 10470716
32931508 32931531 19 - 28162770 SKM1 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.23703919730084966 [17] [26] -2 hSpCas9 negative selection 10470717
32915482 32915505 19 - 28162770 SKM1 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.17799830197799466 [36] [73] 1 hSpCas9 negative selection 10470718
32915385 32915408 19 - 28162770 SKM1 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.20902482113125243 [16] [25] -2 hSpCas9 negative selection 10470719
32901279 32901302 19 - 28162770 SKM1 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.50410207283655 [68] [172] 5 hSpCas9 negative selection 10470720
32881981 32882004 19 - 28162770 SKM1 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.5019713228503813 [140] [352] 5 hSpCas9 negative selection 10470721
32966375 32966398 19 + 28162770 SKM1 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.5256086952417807 [56] [34] -7 hSpCas9 negative selection 10640078
32881872 32881895 19 - 28162770 SKM1 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -3.0850361038557996 [23] [4] -9 hSpCas9 negative selection 10640079
32953697 32953720 19 - 28162770 SKM1 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.15597199564799558 [32] [64] 1 hSpCas9 negative selection 10640080
32937642 32937665 19 + 28162770 SKM1 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.6276089498042645 [66] [182] 6 hSpCas9 negative selection 10640081
32931521 32931544 19 - 28162770 SKM1 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 -0.06909455998677777 [53] [90] 0 hSpCas9 negative selection 10640082
32931508 32931531 19 - 28162770 SKM1 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.23703919730084966 [17] [26] -2 hSpCas9 negative selection 10640083
32915482 32915505 19 - 28162770 SKM1 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.17799830197799466 [36] [73] 1 hSpCas9 negative selection 10640084
32915385 32915408 19 - 28162770 SKM1 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.20902482113125243 [16] [25] -2 hSpCas9 negative selection 10640085
32901279 32901302 19 - 28162770 SKM1 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.50410207283655 [68] [172] 5 hSpCas9 negative selection 10640086
32881981 32882004 19 - 28162770 SKM1 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.5019713228503813 [140] [352] 5 hSpCas9 negative selection 10640087
32966375 32966398 19 + 28162770 PL21 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -0.49464616418458734 [190] [58] -4 hSpCas9 negative selection 10809444
32881872 32881895 19 - 28162770 PL21 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.560672721631254 [60] [8] -7 hSpCas9 negative selection 10809445
32953697 32953720 19 - 28162770 PL21 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 1.0019135042836247 [147] [128] 8 hSpCas9 negative selection 10809446
32937642 32937665 19 + 28162770 PL21 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.5544230826890677 [290] [185] 5 hSpCas9 negative selection 10809447
32931521 32931544 19 - 28162770 PL21 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.1276271147049521 [203] [96] 1 hSpCas9 negative selection 10809448
32931508 32931531 19 - 28162770 PL21 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.12975028659792187 [41] [19] 1 hSpCas9 negative selection 10809449
32915482 32915505 19 - 28162770 PL21 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 1.446933379315903 [133] [158] 9 hSpCas9 negative selection 10809450
32915385 32915408 19 - 28162770 PL21 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.5371746017668908 [37] [23] 5 hSpCas9 negative selection 10809451
32901279 32901302 19 - 28162770 PL21 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.9681928864396232 [201] [171] 7 hSpCas9 negative selection 10809452
32881981 32882004 19 - 28162770 PL21 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.4191493964311157 [365] [212] 3 hSpCas9 negative selection 10809453
32966375 32966398 19 + 28162770 P31FUJ viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.4753725076884567 [167] [70] -7 hSpCas9 negative selection 10978810
32881872 32881895 19 - 28162770 P31FUJ viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.9532796757920157 [144] [43] -8 hSpCas9 negative selection 10978811
32953697 32953720 19 - 28162770 P31FUJ viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.4351103797074942 [106] [92] -4 hSpCas9 negative selection 10978812
32937642 32937665 19 + 28162770 P31FUJ viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.26998578341730045 [294] [417] 3 hSpCas9 negative selection 10978813
32931521 32931544 19 - 28162770 P31FUJ viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.08163135392605941 [192] [239] 0 hSpCas9 negative selection 10978814
32931508 32931531 19 - 28162770 P31FUJ viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.222877279361811 [34] [47] 2 hSpCas9 negative selection 10978815
32915482 32915505 19 - 28162770 P31FUJ viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.07344426824071393 [147] [182] 0 hSpCas9 negative selection 10978816
32915385 32915408 19 - 28162770 P31FUJ viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.30555854684969286 [60] [57] -3 hSpCas9 negative selection 10978817
32901279 32901302 19 - 28162770 P31FUJ viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.4511703021379433 [304] [489] 5 hSpCas9 negative selection 10978818
32881981 32882004 19 - 28162770 P31FUJ viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.2701002810765414 [421] [597] 3 hSpCas9 negative selection 10978819
32966375 32966398 19 + 28162770 OCIAML5 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -0.3888199785425334 [102] [141] -3 hSpCas9 negative selection 11148176
32881872 32881895 19 - 28162770 OCIAML5 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.8240521946944004 [50] [25] -7 hSpCas9 negative selection 11148177
32953697 32953720 19 - 28162770 OCIAML5 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.8125130979205273 [46] [148] 7 hSpCas9 negative selection 11148178
32937642 32937665 19 + 28162770 OCIAML5 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.26474709411875297 [165] [359] 2 hSpCas9 negative selection 11148179
32931521 32931544 19 - 28162770 OCIAML5 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.8186258038830432 [97] [311] 7 hSpCas9 negative selection 11148180
32931508 32931531 19 - 28162770 OCIAML5 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.860651477055532 [17] [58] 7 hSpCas9 negative selection 11148181
32915482 32915505 19 - 28162770 OCIAML5 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -0.591539020640778 [95] [114] -4 hSpCas9 negative selection 11148182
32915385 32915408 19 - 28162770 OCIAML5 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.6863533439201293 [41] [121] 6 hSpCas9 negative selection 11148183
32901279 32901302 19 - 28162770 OCIAML5 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 -0.01523177059634706 [172] [308] 0 hSpCas9 negative selection 11148184
32881981 32882004 19 - 28162770 OCIAML5 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.3829922623086117 [242] [571] 3 hSpCas9 negative selection 11148185
32966375 32966398 19 + 28162770 EOL1 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -0.971829597355308 [375] [100] -6 hSpCas9 negative selection 11317542
32881872 32881895 19 - 28162770 EOL1 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.7635082221147256 [57] [8] -8 hSpCas9 negative selection 11317543
32953697 32953720 19 - 28162770 EOL1 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -1.666566956132217 [234] [38] -8 hSpCas9 negative selection 11317544
32937642 32937665 19 + 28162770 EOL1 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.16421818433881807 [497] [293] 1 hSpCas9 negative selection 11317545
32931521 32931544 19 - 28162770 EOL1 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.12874707614101288 [341] [196] 1 hSpCas9 negative selection 11317546
32931508 32931531 19 - 28162770 EOL1 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -1.573703095957291 [112] [19] -7 hSpCas9 negative selection 11317547
32915482 32915505 19 - 28162770 EOL1 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -1.2115889164154945 [210] [47] -7 hSpCas9 negative selection 11317548
32915385 32915408 19 - 28162770 EOL1 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.9872835269184972 [44] [46] 8 hSpCas9 negative selection 11317549
32901279 32901302 19 - 28162770 EOL1 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 -0.26186535266034694 [263] [115] -2 hSpCas9 negative selection 11317550
32881981 32882004 19 - 28162770 EOL1 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.9701583680908344 [466] [481] 8 hSpCas9 negative selection 11317551
32966375 32966398 19 + 28162770 MOLM13 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.3282818020203497 [256] [73] -6 hSpCas9 negative selection 11486908
32881872 32881895 19 - 28162770 MOLM13 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.934209062026767 [73] [13] -7 hSpCas9 negative selection 11486909
32953697 32953720 19 - 28162770 MOLM13 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.07341189038043772 [178] [122] 0 hSpCas9 negative selection 11486910
32937642 32937665 19 + 28162770 MOLM13 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.6593154521978133 [443] [506] 5 hSpCas9 negative selection 11486911
32931521 32931544 19 - 28162770 MOLM13 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 1.0172279725350137 [204] [299] 7 hSpCas9 negative selection 11486912
32931508 32931531 19 - 28162770 MOLM13 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.20196201676309022 [69] [43] -1 hSpCas9 negative selection 11486913
32915482 32915505 19 - 28162770 MOLM13 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.5446465805286167 [182] [192] 4 hSpCas9 negative selection 11486914
32915385 32915408 19 - 28162770 MOLM13 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.19000464163042863 [70] [44] -1 hSpCas9 negative selection 11486915
32901279 32901302 19 - 28162770 MOLM13 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.24186021756924347 [330] [282] 1 hSpCas9 negative selection 11486916
32881981 32882004 19 - 28162770 MOLM13 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.0991809333212077 [571] [442] 0 hSpCas9 negative selection 11486917
32966375 32966398 19 + 28162770 HEL viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.4254326706412221 [259] [61] -7 hSpCas9 negative selection 11656274
32881872 32881895 19 - 28162770 HEL viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -5.2399042173614845 [58] [0] -9 hSpCas9 negative selection 11656275
32953697 32953720 19 - 28162770 HEL viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.7582160494202927 [143] [155] 6 hSpCas9 negative selection 11656276
32937642 32937665 19 + 28162770 HEL viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.13459192833003164 [383] [269] 1 hSpCas9 negative selection 11656277
32931521 32931544 19 - 28162770 HEL viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.5734761695632432 [255] [243] 5 hSpCas9 negative selection 11656278
32931508 32931531 19 - 28162770 HEL viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.0390852079733881 [76] [47] 0 hSpCas9 negative selection 11656279
32915482 32915505 19 - 28162770 HEL viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -0.25996396664472815 [171] [91] -2 hSpCas9 negative selection 11656280
32915385 32915408 19 - 28162770 HEL viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.006354006140514734 [68] [43] 0 hSpCas9 negative selection 11656281
32901279 32901302 19 - 28162770 HEL viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.13354383889716553 [305] [214] 1 hSpCas9 negative selection 11656282
32881981 32882004 19 - 28162770 HEL viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 -0.03192647166903129 [422] [264] 0 hSpCas9 negative selection 11656283
32966375 32966398 19 + 28162770 MV411 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.4444401538548928 [167] [51] -7 hSpCas9 negative selection 11825640
32881872 32881895 19 - 28162770 MV411 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 0.8754687733958174 [54] [84] 7 hSpCas9 negative selection 11825641
32953697 32953720 19 - 28162770 MV411 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.09246289080643444 [107] [96] 0 hSpCas9 negative selection 11825642
32937642 32937665 19 + 28162770 MV411 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.588707367971143 [325] [412] 5 hSpCas9 negative selection 11825643
32931521 32931544 19 - 28162770 MV411 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.04812874255936872 [154] [134] 0 hSpCas9 negative selection 11825644
32931508 32931531 19 - 28162770 MV411 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.21641065516215074 [46] [45] 1 hSpCas9 negative selection 11825645
32915482 32915505 19 - 28162770 MV411 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.7635611751759334 [92] [132] 7 hSpCas9 negative selection 11825646
32915385 32915408 19 - 28162770 MV411 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.7969565685756779 [32] [15] -5 hSpCas9 negative selection 11825647
32901279 32901302 19 - 28162770 MV411 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.20211356027328498 [193] [187] 1 hSpCas9 negative selection 11825648
32881981 32882004 19 - 28162770 MV411 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.3243455364885569 [346] [365] 3 hSpCas9 negative selection 11825649
32966375 32966398 19 + 28162770 MONOMAC1 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.5449601504798605 [111] [43] -8 hSpCas9 negative selection 11995006
32881872 32881895 19 - 28162770 MONOMAC1 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -1.158562699244918 [36] [18] -7 hSpCas9 negative selection 11995007
32953697 32953720 19 - 28162770 MONOMAC1 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 0.6318512365476917 [75] [134] 6 hSpCas9 negative selection 11995008
32937642 32937665 19 + 28162770 MONOMAC1 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.07469226032664622 [192] [232] 0 hSpCas9 negative selection 11995009
32931521 32931544 19 - 28162770 MONOMAC1 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 0.2520938508876981 [114] [156] 2 hSpCas9 negative selection 11995010
32931508 32931531 19 - 28162770 MONOMAC1 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.9855327418658422 [37] [21] -7 hSpCas9 negative selection 11995011
32915482 32915505 19 - 28162770 MONOMAC1 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -1.3873680591637032 [88] [38] -8 hSpCas9 negative selection 11995012
32915385 32915408 19 - 28162770 MONOMAC1 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.6200990957906358 [20] [36] 6 hSpCas9 negative selection 11995013
32901279 32901302 19 - 28162770 MONOMAC1 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.7365357912014705 [99] [190] 7 hSpCas9 negative selection 11995014
32881981 32882004 19 - 28162770 MONOMAC1 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.21336920348764454 [233] [310] 2 hSpCas9 negative selection 11995015
32966375 32966398 19 + 28162770 OCIAML2 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -1.129592907407094 [29] [75] -6 hSpCas9 negative selection 12164372
32881872 32881895 19 - 28162770 OCIAML2 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -0.9758651334925832 [10] [30] -6 hSpCas9 negative selection 12164373
32953697 32953720 19 - 28162770 OCIAML2 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.16482139571807575 [35] [177] -1 hSpCas9 negative selection 12164374
32937642 32937665 19 + 28162770 OCIAML2 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.48438271998452875 [56] [441] 5 hSpCas9 negative selection 12164375
32931521 32931544 19 - 28162770 OCIAML2 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 -0.17166287879810993 [37] [186] -1 hSpCas9 negative selection 12164376
32931508 32931531 19 - 28162770 OCIAML2 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 -0.27798474729976563 [13] [63] -2 hSpCas9 negative selection 12164377
32915482 32915505 19 - 28162770 OCIAML2 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 -0.19209432586817948 [26] [130] -1 hSpCas9 negative selection 12164378
32915385 32915408 19 - 28162770 OCIAML2 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 -0.849141448495891 [12] [39] -5 hSpCas9 negative selection 12164379
32901279 32901302 19 - 28162770 OCIAML2 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.5240563748613709 [33] [270] 5 hSpCas9 negative selection 12164380
32881981 32882004 19 - 28162770 OCIAML2 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.41752420778477173 [61] [458] 4 hSpCas9 negative selection 12164381
32966375 32966398 19 + 28162770 OCIAML3 viability GATGGGTTGGGGCTGCGGGGAGG CEP89 ENSG00000121289 -0.15660232801686486 [47] [129] -1 hSpCas9 negative selection 12333738
32881872 32881895 19 - 28162770 OCIAML3 viability GGTGCTGAAGGACAAGCAGGAGG CEP89 ENSG00000121289 -2.594007640324163 [17] [8] -9 hSpCas9 negative selection 12333739
32953697 32953720 19 - 28162770 OCIAML3 viability GAAACTCAGCTGTCATCCAGCGG CEP89 ENSG00000121289 -0.3116079096234381 [36] [89] -2 hSpCas9 negative selection 12333740
32937642 32937665 19 + 28162770 OCIAML3 viability GGAGGTTTCTCACATAATGGAGG CEP89 ENSG00000121289 0.6891279715661401 [97] [476] 6 hSpCas9 negative selection 12333741
32931521 32931544 19 - 28162770 OCIAML3 viability AAAACAAGCTCAAGAACTGGTGG CEP89 ENSG00000121289 -0.4944719667732488 [48] [104] -4 hSpCas9 negative selection 12333742
32931508 32931531 19 - 28162770 OCIAML3 viability GAACTGGTGGATGAAAATGATGG CEP89 ENSG00000121289 0.6861002788685718 [20] [101] 6 hSpCas9 negative selection 12333743
32915482 32915505 19 - 28162770 OCIAML3 viability TAAACAACTAATGCTCCTGGAGG CEP89 ENSG00000121289 0.06310464615282829 [25] [81] 0 hSpCas9 negative selection 12333744
32915385 32915408 19 - 28162770 OCIAML3 viability GAACTCAAAACACACTCGGATGG CEP89 ENSG00000121289 0.5214695770957729 [11] [51] 5 hSpCas9 negative selection 12333745
32901279 32901302 19 - 28162770 OCIAML3 viability GACAGAGCAAAACAAAGCACTGG CEP89 ENSG00000121289 0.5129075635923488 [64] [279] 5 hSpCas9 negative selection 12333746
32881981 32882004 19 - 28162770 OCIAML3 viability AGCAGGCAGCACTGAAGCTGGGG CEP89 ENSG00000121289 0.9231767459621331 [68] [394] 7 hSpCas9 negative selection 12333747