Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 22894
  • Symbol: DIS3
  • Description: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
DataSource: http://genomecrispr.dkfz.de/#!/results/DIS3

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
72781624 72781647 13 + 26472758 Jiyoye viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -1.314360172090727 [464] [140] -7 hSpCas9 negative selection 44355
72766022 72766045 13 + 26472758 Jiyoye viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -1.996180312725335 [163] [30] -8 hSpCas9 negative selection 44356
72771842 72771865 13 - 26472758 Jiyoye viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -0.5928246184941266 [165] [82] -4 hSpCas9 negative selection 44357
72771820 72771843 13 - 26472758 Jiyoye viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -0.26098105474168143 [115] [72] -2 hSpCas9 negative selection 44358
72761654 72761677 13 + 26472758 Jiyoye viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 1.0502408367905978 [72] [113] 7 hSpCas9 negative selection 44359
72781709 72781732 13 - 26472758 Jiyoye viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -2.2332822318069865 [105] [16] -8 hSpCas9 negative selection 44360
72781699 72781722 13 - 26472758 Jiyoye viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -0.4972469585118955 [72] [38] -4 hSpCas9 negative selection 44361
72773735 72773758 13 - 26472758 Jiyoye viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 4.494638222756212 [0] [16] 9 hSpCas9 negative selection 44362
72772708 72772731 13 - 26472758 Jiyoye viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 0.32471322131390035 [35] [33] 2 hSpCas9 negative selection 44363
72771085 72771108 13 - 26472758 Jiyoye viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.0210616155278296 [182] [33] -8 hSpCas9 negative selection 44364
72781624 72781647 13 + 26472758 KBM7 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -4.057041595605166 [1576,1476] [29,54] -9 hSpCas9 negative selection 235473
72766022 72766045 13 + 26472758 KBM7 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -0.610132713151578 [472,503] [147,154] -5 hSpCas9 negative selection 235474
72771842 72771865 13 - 26472758 KBM7 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -1.385806741192137 [808,575] [102,140] -7 hSpCas9 negative selection 235475
72771820 72771843 13 - 26472758 KBM7 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -2.168815317335171 [475,395] [56,34] -8 hSpCas9 negative selection 235476
72761654 72761677 13 + 26472758 KBM7 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.8892432633190539 [430,361] [439,257] 8 hSpCas9 negative selection 235477
72781709 72781732 13 - 26472758 KBM7 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -1.954303739835113 [351,294] [27,48] -8 hSpCas9 negative selection 235478
72781699 72781722 13 - 26472758 KBM7 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -2.612770698762545 [484,594] [29,52] -9 hSpCas9 negative selection 235479
72773735 72773758 13 - 26472758 KBM7 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -2.347800752981982 [98,135] [18,3] -9 hSpCas9 negative selection 235480
72772708 72772731 13 - 26472758 KBM7 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 0.11029767547697744 [305,223] [141,124] 1 hSpCas9 negative selection 235481
72771085 72771108 13 - 26472758 KBM7 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.4251085980442166 [624,610] [57,50] -9 hSpCas9 negative selection 235482
72781624 72781647 13 + 26472758 Raji viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -1.365104236089144 [665] [59] -7 hSpCas9 negative selection 426591
72766022 72766045 13 + 26472758 Raji viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -1.5744405046001455 [307] [23] -8 hSpCas9 negative selection 426592
72771842 72771865 13 - 26472758 Raji viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.1447562293569007 [342] [17] -8 hSpCas9 negative selection 426593
72771820 72771843 13 - 26472758 Raji viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -1.5364726544011253 [299] [23] -8 hSpCas9 negative selection 426594
72761654 72761677 13 + 26472758 Raji viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 1.7717805035891607 [105] [83] 9 hSpCas9 negative selection 426595
72781709 72781732 13 - 26472758 Raji viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -1.907566806092372 [193] [11] -8 hSpCas9 negative selection 426596
72781699 72781722 13 - 26472758 Raji viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.7194675623098017 [297] [20] -8 hSpCas9 negative selection 426597
72773735 72773758 13 - 26472758 Raji viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.039457852955672 [61] [6] -6 hSpCas9 negative selection 426598
72772708 72772731 13 - 26472758 Raji viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 0.14159925071151236 [124] [31] 1 hSpCas9 negative selection 426599
72771085 72771108 13 - 26472758 Raji viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.438408368066879 [326] [27] -7 hSpCas9 negative selection 426600
72781624 72781647 13 + 26472758 K562 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -3.7157064747944024 [1462] [93] -9 hSpCas9 negative selection 617709
72766022 72766045 13 + 26472758 K562 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -2.4687694832166334 [340] [51] -8 hSpCas9 negative selection 617710
72771842 72771865 13 - 26472758 K562 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -3.138391609367938 [604] [57] -8 hSpCas9 negative selection 617711
72771820 72771843 13 - 26472758 K562 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -5.189282615877433 [388] [8] -9 hSpCas9 negative selection 617712
72761654 72761677 13 + 26472758 K562 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.18693323300568682 [383] [368] 1 hSpCas9 negative selection 617713
72781709 72781732 13 - 26472758 K562 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -5.4280066143050485 [356] [6] -9 hSpCas9 negative selection 617714
72781699 72781722 13 - 26472758 K562 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -3.591631627391623 [456] [31] -8 hSpCas9 negative selection 617715
72773735 72773758 13 - 26472758 K562 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -6.022367813028454 [76] [0] -9 hSpCas9 negative selection 617716
72772708 72772731 13 - 26472758 K562 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -1.2567754153621113 [183] [64] -6 hSpCas9 negative selection 617717
72771085 72771108 13 - 26472758 K562 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.390495595030062 [381] [122] -6 hSpCas9 negative selection 617718
72762012 72762035 13 + 26627737 DLD1 viability AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -0.8691960534683594 [340] [27,34,103] -7 hSpCas9 negative selection 787200
72765979 72766002 13 - 26627737 DLD1 viability TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -2.733877554535381 [688] [13,10,65] -9 hSpCas9 negative selection 787201
72772217 72772240 13 - 26627737 DLD1 viability ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.3653406985258931 [136] [18,32,0] -8 hSpCas9 negative selection 787202
72773778 72773801 13 + 26627737 DLD1 viability CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.386959809555791 [430] [250,56,209] 4 hSpCas9 negative selection 787203
72780902 72780925 13 + 26627737 DLD1 viability TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.844121786716927 [375] [22,9,59] -8 hSpCas9 negative selection 787204
72781604 72781627 13 - 26627737 DLD1 viability CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.5695200230006745 [639] [46,81,72] -8 hSpCas9 negative selection 787205
72762012 72762035 13 + 26627737 GBM cells viability after 5 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -2.126621217221452 [113] [18,8] -9 hSpCas9 negative selection 869515
72765979 72766002 13 - 26627737 GBM cells viability after 5 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.31697258259135225 [294] [129,123] -5 hSpCas9 negative selection 869516
72772217 72772240 13 - 26627737 GBM cells viability after 5 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.25132876069492704 [90] [38,42] -4 hSpCas9 negative selection 869517
72773778 72773801 13 + 26627737 GBM cells viability after 5 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.8234381450098194 [205] [184,205] 9 hSpCas9 negative selection 869518
72780902 72780925 13 + 26627737 GBM cells viability after 5 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.4925551532547536 [424] [81,79] -9 hSpCas9 negative selection 869519
72781604 72781627 13 - 26627737 GBM cells viability after 5 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -0.018985044899420545 [221] [91,142] 0 hSpCas9 negative selection 869520
72762012 72762035 13 + 26627737 GBM cells viability after 13 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.9634392706761794 [113] [11,18] -9 hSpCas9 negative selection 951830
72765979 72766002 13 - 26627737 GBM cells viability after 13 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.9277531507336496 [294] [87,80] -8 hSpCas9 negative selection 951831
72772217 72772240 13 - 26627737 GBM cells viability after 13 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.6762939111975421 [90] [31,29] -7 hSpCas9 negative selection 951832
72773778 72773801 13 + 26627737 GBM cells viability after 13 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.47446196939070523 [205] [194,122] 6 hSpCas9 negative selection 951833
72780902 72780925 13 + 26627737 GBM cells viability after 13 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.7187210508328423 [424] [11,21] -9 hSpCas9 negative selection 951834
72781604 72781627 13 - 26627737 GBM cells viability after 13 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.4803850426740377 [221] [35,48] -9 hSpCas9 negative selection 951835
72762012 72762035 13 + 26627737 GBM cells viability after 21 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -2.9446639237955523 [113] [6,8] -9 hSpCas9 negative selection 1034145
72765979 72766002 13 - 26627737 GBM cells viability after 21 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.9846857558778936 [294] [92,69] -7 hSpCas9 negative selection 1034146
72772217 72772240 13 - 26627737 GBM cells viability after 21 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.5586039681847716 [90] [31,34] -5 hSpCas9 negative selection 1034147
72773778 72773801 13 + 26627737 GBM cells viability after 21 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.7443085616034538 [205] [187,186] 7 hSpCas9 negative selection 1034148
72780902 72780925 13 + 26627737 GBM cells viability after 21 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -5.688302799211113 [424] [4,3] -9 hSpCas9 negative selection 1034149
72781604 72781627 13 - 26627737 GBM cells viability after 21 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.0562015716068753 [221] [28,28] -9 hSpCas9 negative selection 1034150
72762012 72762035 13 + 26627737 RPE1 viability after 9 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -3.4864314297749943 [417] [5,18] -9 hSpCas9 negative selection 1116460
72765979 72766002 13 - 26627737 RPE1 viability after 9 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.8433743342724354 [797] [97,32] -8 hSpCas9 negative selection 1116461
72772217 72772240 13 - 26627737 RPE1 viability after 9 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -5.616522661842327 [244] [1,0] -9 hSpCas9 negative selection 1116462
72773778 72773801 13 + 26627737 RPE1 viability after 9 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.17535466455221682 [366] [68,143] -1 hSpCas9 negative selection 1116463
72780902 72780925 13 + 26627737 RPE1 viability after 9 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -4.015679505931341 [1132] [17,26] -9 hSpCas9 negative selection 1116464
72781604 72781627 13 - 26627737 RPE1 viability after 9 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.34807953669296 [565] [60,0] -9 hSpCas9 negative selection 1116465
72762012 72762035 13 + 26627737 RPE1 viability after 12 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -2.692603223909126 [417] [12,21] -9 hSpCas9 negative selection 1198775
72765979 72766002 13 - 26627737 RPE1 viability after 12 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -2.5684948719125016 [797] [40,30] -9 hSpCas9 negative selection 1198776
72772217 72772240 13 - 26627737 RPE1 viability after 12 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -4.204025259612313 [244] [5,0] -9 hSpCas9 negative selection 1198777
72773778 72773801 13 + 26627737 RPE1 viability after 12 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.9502914929938184 [366] [68,31] -6 hSpCas9 negative selection 1198778
72780902 72780925 13 + 26627737 RPE1 viability after 12 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -5.952838996390247 [1132] [1,7] -9 hSpCas9 negative selection 1198779
72781604 72781627 13 - 26627737 RPE1 viability after 12 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.0947414950797087 [565] [4,67] -8 hSpCas9 negative selection 1198780
72762012 72762035 13 + 26627737 RPE1 viability after 15 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -3.161266174771241 [417] [0,24] -9 hSpCas9 negative selection 1281090
72765979 72766002 13 - 26627737 RPE1 viability after 15 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -2.9371813596251273 [797] [30,27] -9 hSpCas9 negative selection 1281091
72772217 72772240 13 - 26627737 RPE1 viability after 15 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -4.547440528097295 [244] [4,0] -9 hSpCas9 negative selection 1281092
72773778 72773801 13 + 26627737 RPE1 viability after 15 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -3.399653713335441 [366] [18,0] -9 hSpCas9 negative selection 1281093
72780902 72780925 13 + 26627737 RPE1 viability after 15 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -6.498296366867472 [1132] [0,5] -9 hSpCas9 negative selection 1281094
72781604 72781627 13 - 26627737 RPE1 viability after 15 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -0.8963410168155049 [565] [84,86] -5 hSpCas9 negative selection 1281095
72762012 72762035 13 + 26627737 RPE1 viability after 18 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -6.8176908719801395 [417] [0,0] -9 hSpCas9 negative selection 1363405
72765979 72766002 13 - 26627737 RPE1 viability after 18 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -2.597655097169812 [797] [66,1] -8 hSpCas9 negative selection 1363406
72772217 72772240 13 - 26627737 RPE1 viability after 18 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -6.046969678901828 [244] [0,0] -9 hSpCas9 negative selection 1363407
72773778 72773801 13 + 26627737 RPE1 viability after 18 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -1.6443553364689405 [366] [36,25] -7 hSpCas9 negative selection 1363408
72780902 72780925 13 + 26627737 RPE1 viability after 18 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -6.483507625186136 [1132] [0,5] -9 hSpCas9 negative selection 1363409
72781604 72781627 13 - 26627737 RPE1 viability after 18 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.8821764877727634 [565] [24,58] -8 hSpCas9 negative selection 1363410
72762012 72762035 13 + 26627737 HeLa viability after 8 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -0.2810280445483966 [144] [123,0,46] -3 hSpCas9 negative selection 1445720
72765979 72766002 13 - 26627737 HeLa viability after 8 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.0753325128717048 [367] [165,8,72] -8 hSpCas9 negative selection 1445721
72772217 72772240 13 - 26627737 HeLa viability after 8 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.1950010104812196 [358] [20,70,99] -8 hSpCas9 negative selection 1445722
72773778 72773801 13 + 26627737 HeLa viability after 8 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.5304982041652536 [439] [247,11,160] -5 hSpCas9 negative selection 1445723
72780902 72780925 13 + 26627737 HeLa viability after 8 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.4845259086051454 [459] [41,20,44] -9 hSpCas9 negative selection 1445724
72781604 72781627 13 - 26627737 HeLa viability after 8 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.0584377565613385 [261] [45,71,44] -8 hSpCas9 negative selection 1445725
72762012 72762035 13 + 26627737 HeLa viability after 12 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.3256188514807874 [144] [17,47,2] -8 hSpCas9 negative selection 1528035
72765979 72766002 13 - 26627737 HeLa viability after 12 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.399196625068689 [367] [55,126,159] -4 hSpCas9 negative selection 1528036
72772217 72772240 13 - 26627737 HeLa viability after 12 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.8209159627306226 [358] [60,46,17] -9 hSpCas9 negative selection 1528037
72773778 72773801 13 + 26627737 HeLa viability after 12 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.3794128130175524 [439] [172,123,124] -3 hSpCas9 negative selection 1528038
72780902 72780925 13 + 26627737 HeLa viability after 12 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.2648160142809313 [459] [194,47,0] -8 hSpCas9 negative selection 1528039
72781604 72781627 13 - 26627737 HeLa viability after 12 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -0.608942353553897 [261] [8,100,97] -5 hSpCas9 negative selection 1528040
72762012 72762035 13 + 26627737 HeLa viability after 15 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.0384737848886687 [144] [35,46,0] -7 hSpCas9 negative selection 1610350
72765979 72766002 13 - 26627737 HeLa viability after 15 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.8862698717367978 [367] [67,73,102] -7 hSpCas9 negative selection 1610351
72772217 72772240 13 - 26627737 HeLa viability after 15 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -2.217584382622643 [358] [19,47,25] -9 hSpCas9 negative selection 1610352
72773778 72773801 13 + 26627737 HeLa viability after 15 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.37457644215257707 [439] [160,44,213] -3 hSpCas9 negative selection 1610353
72780902 72780925 13 + 26627737 HeLa viability after 15 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.4816715931287399 [459] [75,118,0] -8 hSpCas9 negative selection 1610354
72781604 72781627 13 - 26627737 HeLa viability after 15 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.358822061110652 [261] [20,98,1] -8 hSpCas9 negative selection 1610355
72762012 72762035 13 + 26627737 HeLa viability after 18 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -0.9800206405821388 [144] [23,41,0] -7 hSpCas9 negative selection 1692665
72765979 72766002 13 - 26627737 HeLa viability after 18 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.9144060648143522 [367] [45,56,102] -7 hSpCas9 negative selection 1692666
72772217 72772240 13 - 26627737 HeLa viability after 18 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -2.2905781159881813 [358] [10,38,25] -9 hSpCas9 negative selection 1692667
72773778 72773801 13 + 26627737 HeLa viability after 18 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.3251586340033388 [439] [115,38,213] -3 hSpCas9 negative selection 1692668
72780902 72780925 13 + 26627737 HeLa viability after 18 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.446937215820677 [459] [52,99,0] -8 hSpCas9 negative selection 1692669
72781604 72781627 13 - 26627737 HeLa viability after 18 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.3248046235563646 [261] [11,86,1] -8 hSpCas9 negative selection 1692670
72762012 72762035 13 + 26627737 HCT116 viability after 6 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -5.267377681815003 [244] [0,0] -9 hSpCas9 negative selection 1774980
72765979 72766002 13 - 26627737 HCT116 viability after 6 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.709702671741236 [793] [143,38] -4 hSpCas9 negative selection 1774981
72772217 72772240 13 - 26627737 HCT116 viability after 6 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.3082638804544289 [293] [37,7] -6 hSpCas9 negative selection 1774982
72773778 72773801 13 + 26627737 HCT116 viability after 6 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.5857274360934854 [707] [313,85] 3 hSpCas9 negative selection 1774983
72780902 72780925 13 + 26627737 HCT116 viability after 6 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.5404096128312026 [757] [26,0] -9 hSpCas9 negative selection 1774984
72781604 72781627 13 - 26627737 HCT116 viability after 6 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 1.7113550568189053 [270] [134,141] 8 hSpCas9 negative selection 1774985
72762012 72762035 13 + 26627737 HCT116 viability after 8 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -0.4995457031619376 [155] [31,97,51] -5 hSpCas9 negative selection 1857295
72765979 72766002 13 - 26627737 HCT116 viability after 8 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.724854405899749 [272] [93,78,99] -7 hSpCas9 negative selection 1857296
72772217 72772240 13 - 26627737 HCT116 viability after 8 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.8939444149649395 [194] [43,52,75] -8 hSpCas9 negative selection 1857297
72773778 72773801 13 + 26627737 HCT116 viability after 8 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.2488472421146014 [426] [146,237,207] -3 hSpCas9 negative selection 1857298
72780902 72780925 13 + 26627737 HCT116 viability after 8 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.9885163593055815 [370] [24,4,46] -9 hSpCas9 negative selection 1857299
72781604 72781627 13 - 26627737 HCT116 viability after 8 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -0.3938312979669045 [193] [85,62,94] -5 hSpCas9 negative selection 1857300
72762012 72762035 13 + 26627737 HCT116 viability after 9 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -6.0316481276491025 [244] [0,0] -9 hSpCas9 negative selection 1939610
72765979 72766002 13 - 26627737 HCT116 viability after 9 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.7391160323918008 [793] [40,194] -5 hSpCas9 negative selection 1939611
72772217 72772240 13 - 26627737 HCT116 viability after 9 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 1.2593531375741263 [293] [159,209] 8 hSpCas9 negative selection 1939612
72773778 72773801 13 + 26627737 HCT116 viability after 9 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.48080245883627726 [707] [130,138] -3 hSpCas9 negative selection 1939613
72780902 72780925 13 + 26627737 HCT116 viability after 9 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.3320052949235888 [757] [42,1] -9 hSpCas9 negative selection 1939614
72781604 72781627 13 - 26627737 HCT116 viability after 9 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 1.1044889012871837 [270] [106,193] 7 hSpCas9 negative selection 1939615
72762012 72762035 13 + 26627737 HCT116 viability after 12 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.6352103154338828 [155] [5,68,6] -9 hSpCas9 negative selection 2021925
72765979 72766002 13 - 26627737 HCT116 viability after 12 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.3226510938414646 [272] [81,60,26] -8 hSpCas9 negative selection 2021926
72772217 72772240 13 - 26627737 HCT116 viability after 12 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.5879644231732728 [194] [20,16,64] -9 hSpCas9 negative selection 2021927
72773778 72773801 13 + 26627737 HCT116 viability after 12 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.5825887024618056 [426] [113,203,135] -6 hSpCas9 negative selection 2021928
72780902 72780925 13 + 26627737 HCT116 viability after 12 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.5484946944404383 [370] [34,0,11] -9 hSpCas9 negative selection 2021929
72781604 72781627 13 - 26627737 HCT116 viability after 12 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.0167197269759456 [193] [52,52,44] -8 hSpCas9 negative selection 2021930
72762012 72762035 13 + 26627737 HCT116 viability after 15 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.4417342366206527 [155] [0,56,36] -8 hSpCas9 negative selection 2104240
72765979 72766002 13 - 26627737 HCT116 viability after 15 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.6604723512414978 [272] [59,35,53] -9 hSpCas9 negative selection 2104241
72772217 72772240 13 - 26627737 HCT116 viability after 15 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.2907094963692103 [194] [28,36,68] -8 hSpCas9 negative selection 2104242
72773778 72773801 13 + 26627737 HCT116 viability after 15 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.8315674309478434 [426] [118,145,145] -7 hSpCas9 negative selection 2104243
72780902 72780925 13 + 26627737 HCT116 viability after 15 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.8644240175528743 [370] [25,0,59] -9 hSpCas9 negative selection 2104244
72781604 72781627 13 - 26627737 HCT116 viability after 15 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.148067069530084 [193] [34,66,46] -8 hSpCas9 negative selection 2104245
72762012 72762035 13 + 26627737 HCT116 viability after 18 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -3.8487636421518934 [155] [0,12,0] -9 hSpCas9 negative selection 2186555
72765979 72766002 13 - 26627737 HCT116 viability after 18 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.5822424552340417 [272] [21,37,73] -8 hSpCas9 negative selection 2186556
72772217 72772240 13 - 26627737 HCT116 viability after 18 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.857489941779597 [194] [11,34,112] -7 hSpCas9 negative selection 2186557
72773778 72773801 13 + 26627737 HCT116 viability after 18 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -1.5673515493106513 [426] [78,56,73] -8 hSpCas9 negative selection 2186558
72780902 72780925 13 + 26627737 HCT116 viability after 18 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -4.115821264221938 [370] [12,0,17] -9 hSpCas9 negative selection 2186559
72781604 72781627 13 - 26627737 HCT116 viability after 18 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.857314631483108 [193] [35,1,0] -9 hSpCas9 negative selection 2186560
72781609 72781632 13 + 24336569 HL60 viability TGCAGTAACACATTAGTGTCGGG DIS3 ENSG00000083520 -0.6010728633559529 [409] [571] -5 hSpCas9 negative selection 2260765
72781624 72781647 13 + 24336569 HL60 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -2.68257402392665 [1167] [384] -9 hSpCas9 negative selection 2260766
72781630 72781653 13 + 24336569 HL60 viability GGCAGCAAGTAGTGCGGTTGCGG DIS3 ENSG00000083520 0.2611728910905749 [331] [841] 2 hSpCas9 negative selection 2260767
72781648 72781671 13 + 24336569 HL60 viability TGCGGGCAGACGCTGCTCGCCGG DIS3 ENSG00000083520 0.9144127326866898 [437] [1746] 7 hSpCas9 negative selection 2260768
72781655 72781678 13 + 24336569 HL60 viability AGACGCTGCTCGCCGGGTCCTGG DIS3 ENSG00000083520 -0.09218326203092664 [742] [1474] -1 hSpCas9 negative selection 2260769
72781710 72781733 13 - 24336569 HL60 viability CCGGGTGCGCAGCGTGTGGAGGG DIS3 ENSG00000083520 -2.225460637080683 [578] [261] -9 hSpCas9 negative selection 2260770
72781728 72781751 13 - 24336569 HL60 viability ACATCGGCTGCGGTGCGCCCGGG DIS3 ENSG00000083520 -1.109049932300796 [527] [517] -7 hSpCas9 negative selection 2260771
72781738 72781761 13 - 24336569 HL60 viability CTGCGAGACGACATCGGCTGCGG DIS3 ENSG00000083520 -0.8860684116704657 [392] [449] -7 hSpCas9 negative selection 2260772
72781744 72781767 13 - 24336569 HL60 viability CACTACCTGCGAGACGACATCGG DIS3 ENSG00000083520 -0.2827223088760003 [575] [1001] -2 hSpCas9 negative selection 2260773
72781778 72781801 13 + 24336569 HL60 viability TCTTCATCACGCCGCCCGCCCGG DIS3 ENSG00000083520 7.061919113360925 [3] [1130] 9 hSpCas9 negative selection 2260774
72781609 72781632 13 + 24336569 KBM7 viability TGCAGTAACACATTAGTGTCGGG DIS3 ENSG00000083520 -1.7663190138051976 [564] [452] -8 hSpCas9 negative selection 2327942
72781624 72781647 13 + 24336569 KBM7 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -5.366199084739509 [740] [48] -9 hSpCas9 negative selection 2327943
72781630 72781653 13 + 24336569 KBM7 viability GGCAGCAAGTAGTGCGGTTGCGG DIS3 ENSG00000083520 -1.0813808347340041 [352] [454] -7 hSpCas9 negative selection 2327944
72781648 72781671 13 + 24336569 KBM7 viability TGCGGGCAGACGCTGCTCGCCGG DIS3 ENSG00000083520 0.5310471526585504 [577] [2277] 5 hSpCas9 negative selection 2327945
72781655 72781678 13 + 24336569 KBM7 viability AGACGCTGCTCGCCGGGTCCTGG DIS3 ENSG00000083520 0.3953770933055374 [445] [1599] 3 hSpCas9 negative selection 2327946
72781710 72781733 13 - 24336569 KBM7 viability CCGGGTGCGCAGCGTGTGGAGGG DIS3 ENSG00000083520 -1.5901835919916825 [254] [230] -8 hSpCas9 negative selection 2327947
72781728 72781751 13 - 24336569 KBM7 viability ACATCGGCTGCGGTGCGCCCGGG DIS3 ENSG00000083520 -3.122039848109141 [398] [124] -9 hSpCas9 negative selection 2327948
72781738 72781761 13 - 24336569 KBM7 viability CTGCGAGACGACATCGGCTGCGG DIS3 ENSG00000083520 -4.700920206178832 [266] [27] -9 hSpCas9 negative selection 2327949
72781744 72781767 13 - 24336569 KBM7 viability CACTACCTGCGAGACGACATCGG DIS3 ENSG00000083520 -3.2788247388145075 [821] [230] -9 hSpCas9 negative selection 2327950
72781778 72781801 13 + 24336569 KBM7 viability TCTTCATCACGCCGCCCGCCCGG DIS3 ENSG00000083520 8.173556916725758 [1] [1574] 9 hSpCas9 negative selection 2327951
72781937 72781960 13 + 25494202 A375 resistance to PLX-4720 (puromycin) ATATTAGTAACACTTCTCGCGGG DIS3 ENSG00000083520 1.0479299745159154 [72,26] [13,31] 4 dCas9-VP64 positive selection 2439885
72781963 72781986 13 + 25494202 A375 resistance to PLX-4720 (puromycin) ATGCCGAGATAAACATTGGTTGG DIS3 ENSG00000083520 1.789516016409388 [12,35] [17,19] 6 dCas9-VP64 positive selection 2439886
72781893 72781916 13 + 25494202 A375 resistance to PLX-4720 (puromycin) TAGAATACGCCTAACCCCGGAGG DIS3 ENSG00000083520 1.0696480979529928 [5,17] [4,5] 4 dCas9-VP64 positive selection 2439887
72781937 72781960 13 + 25494202 A375 resistance to PLX-4720 (zeocin) ATATTAGTAACACTTCTCGCGGG DIS3 ENSG00000083520 -1.0832472467921763 [156,37] [19,8] -9 dCas9-VP64 positive selection 2535140
72781963 72781986 13 + 25494202 A375 resistance to PLX-4720 (zeocin) ATGCCGAGATAAACATTGGTTGG DIS3 ENSG00000083520 0.49918858774579133 [59,59] [14,37] 4 dCas9-VP64 positive selection 2535141
72781893 72781916 13 + 25494202 A375 resistance to PLX-4720 (zeocin) TAGAATACGCCTAACCCCGGAGG DIS3 ENSG00000083520 -0.31538654569488994 [101,194] [42,33] -3 dCas9-VP64 positive selection 2535142
72778354 72778377 13 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 -0.16652385956402313 [4,4] [2,3] -2 hSpCas9 positive selection 2983620
72781339 72781362 13 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 -0.07228156446266934 [4,4] [4,2] -1 hSpCas9 positive selection 2983621
72775291 72775314 13 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 -0.11041343256298183 [2,2] [2,1] -1 hSpCas9 positive selection 2983622
72781625 72781648 13 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -1.058719877995792 [2,3] [0,0] -9 hSpCas9 positive selection 2983623
72778354 72778377 13 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 0.302720680568067 [4,4] [3,3] 5 hSpCas9 positive selection 3051478
72781339 72781362 13 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 -0.28269967406285684 [4,4] [2,1] -4 hSpCas9 positive selection 3051479
72775291 72775314 13 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 0.06762828558949718 [2,2] [4,0] 1 hSpCas9 positive selection 3051480
72781625 72781648 13 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -0.36361419557121477 [2,2] [1,0] -5 hSpCas9 positive selection 3051481
72777438 72777461 + 24336571 A375 resistance to PLX after 7 days AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.08997306127189356 [11,12] [11,10] -3 hSpCas9 positive selection 3109819
72778177 72778200 + 24336571 A375 resistance to PLX after 7 days TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 0.031155164325310736 [3,2] [3,3] 1 hSpCas9 positive selection 3109820
72778244 72778267 + 24336571 A375 resistance to PLX after 7 days TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 0.13108933458791883 [15,15] [15,18] 4 hSpCas9 positive selection 3109821
72777438 72777461 + 24336571 A375 resistance to PLX after 14 days AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 0.2969252979002206 [7,3] [2,2] 3 hSpCas9 positive selection 3167612
72778177 72778200 + 24336571 A375 resistance to PLX after 14 days TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 0.6371040202767217 [1,2] [1,1] 6 hSpCas9 positive selection 3167613
72778244 72778267 + 24336571 A375 resistance to PLX after 14 days TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 0.540425716397411 [11,12] [7,8] 5 hSpCas9 positive selection 3167614
72777438 72777461 + 24336571 A375 viability after 7 days AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.4834974220744656 [18] [11,12] -6 hSpCas9 negative selection 3225405
72778177 72778200 + 24336571 A375 viability after 7 days TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.7449999826215408 [13] [3,2] -9 hSpCas9 negative selection 3225406
72778244 72778267 + 24336571 A375 viability after 7 days TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 0.08391835143843268 [15] [15,15] 1 hSpCas9 negative selection 3225407
72777438 72777461 + 24336571 A375 viability after 14 days AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.4899815539699302 [18] [7,3] -9 hSpCas9 negative selection 3283198
72778177 72778200 + 24336571 A375 viability after 14 days TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -2.133307238912193 [13] [1,2] -9 hSpCas9 negative selection 3283199
72778244 72778267 + 24336571 A375 viability after 14 days TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 -0.2504544016535878 [15] [11,12] -3 hSpCas9 negative selection 3283200
72778302 72778325 13 - 27383988 293T resistance to West Nile virus (flavivirus) CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 3.0098950665056456 [17,19] [0,0] 8 hSpCas9 positive selection 3346322
72776027 72776050 13 + 27383988 293T resistance to West Nile virus (flavivirus) GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.5972773917263879 [224,237] [0,0] -4 hSpCas9 positive selection 3346323
72776028 72776051 13 - 27383988 293T resistance to West Nile virus (flavivirus) CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 1.9171270145522712 [41,38] [0,0] 7 hSpCas9 positive selection 3346324
72777438 72777461 13 + 27383988 293T resistance to West Nile virus (flavivirus) AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 0.9174762085612103 [80,80] [0,0] 4 hSpCas9 positive selection 3365525
72778177 72778200 13 + 27383988 293T resistance to West Nile virus (flavivirus) TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 2.0478728458168853 [36,36] [0,0] 7 hSpCas9 positive selection 3365526
72777421 72777444 13 - 27383988 293T resistance to West Nile virus (flavivirus) CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 -0.631417037452424 [236,236] [0,0] -4 hSpCas9 positive selection 3365527
72778354 72778377 13 - 26780180 HT29 viability (Avana library 4 designs) ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 2.46498098140256 [] [] 8 hSpCas9 negative selection 3420383
72781339 72781362 13 - 26780180 HT29 viability (Avana library 4 designs) CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 1.11915793602974 [] [] 4 hSpCas9 negative selection 3420384
72775291 72775314 13 - 26780180 HT29 viability (Avana library 4 designs) GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 3.05822733876578 [] [] 8 hSpCas9 negative selection 3420385
72781624 72781647 13 + 26780180 HT29 viability (Avana library 4 designs) GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 5.3068476826636 [] [] 9 hSpCas9 negative selection 3420386
72778354 72778377 13 - 26780180 A375 viability (Avana lentiCRISPRv2) ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 -9.76081977025668 [] [] -7 hSpCas9 negative selection 3500040
72775291 72775314 13 - 26780180 A375 viability (Avana lentiCRISPRv2) GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 -2.45569441102443 [] [] -3 hSpCas9 negative selection 3500041
72781339 72781362 13 - 26780180 A375 viability (Avana lentiCRISPRv2) CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 0.0921110156305078 [] [] 0 hSpCas9 negative selection 3500042
72781624 72781647 13 + 26780180 A375 viability (Avana lentiCRISPRv2) GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -17.7318251946386 [] [] -9 hSpCas9 negative selection 3500043
72781793 72781816 13 - 26780180 A375 viability (Avana lentiCRISPRv2) GTTCTTAAAAAAGACCCGGGCGG DIS3 ENSG00000083520 -4.7711183386336 [] [] -5 hSpCas9 negative selection 3500044
72776028 72776051 13 + 26780180 A375 viability (Avana lentiCRISPRv2) CCTTGCTGTAGCTTACTTAAGGG DIS3 ENSG00000083520 -6.3636225797436 [] [] -6 hSpCas9 negative selection 3500045
72778354 72778377 13 - 26780180 A375 viability (Avana lentiGuide) ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 12.3917757985102 [] [] 7 hSpCas9 negative selection 3608699
72775291 72775314 13 - 26780180 A375 viability (Avana lentiGuide) GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 10.5314353167729 [] [] 7 hSpCas9 negative selection 3608700
72781339 72781362 13 - 26780180 A375 viability (Avana lentiGuide) CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 1.12928541702686 [] [] 1 hSpCas9 negative selection 3608701
72781624 72781647 13 + 26780180 A375 viability (Avana lentiGuide) GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 31.4150182360418 [] [] 9 hSpCas9 negative selection 3608702
72781793 72781816 13 - 26780180 A375 viability (Avana lentiGuide) GTTCTTAAAAAAGACCCGGGCGG DIS3 ENSG00000083520 21.319837549839 [] [] 9 hSpCas9 negative selection 3608703
72776028 72776051 13 + 26780180 A375 viability (Avana lentiGuide) CCTTGCTGTAGCTTACTTAAGGG DIS3 ENSG00000083520 13.2709982008621 [] [] 7 hSpCas9 negative selection 3608704
72778354 72778377 13 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 -0.45406213757219427 [7] [5,4] -6 hSpCas9 positive selection 3717358
72775291 72775314 13 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 -0.37193689663078755 [3] [4,1] -5 hSpCas9 positive selection 3717359
72781339 72781362 13 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 -0.21601683315852344 [5] [4,3] -3 hSpCas9 positive selection 3717360
72781624 72781647 13 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -0.99036127703174 [4] [2,0] -8 hSpCas9 positive selection 3717361
72781793 72781816 13 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GTTCTTAAAAAAGACCCGGGCGG DIS3 ENSG00000083520 -0.4125670500994837 [4] [4,2] -6 hSpCas9 positive selection 3717362
72776028 72776051 13 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CCTTGCTGTAGCTTACTTAAGGG DIS3 ENSG00000083520 -0.5321814816564496 [5] [4,2] -6 hSpCas9 positive selection 3717363
72778354 72778377 13 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACCTATGTAGAACAAGAACAGGG DIS3 ENSG00000083520 -0.06858506654280397 [6] [4,5] -1 hSpCas9 positive selection 3825965
72775291 72775314 13 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTTCTCCCCAAGAGTCAGTGGG DIS3 ENSG00000083520 -0.7687360060050296 [5] [2,1] -7 hSpCas9 positive selection 3825966
72781339 72781362 13 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTTAGATTGTAAGTGCCTGGAGG DIS3 ENSG00000083520 -0.21097455753768202 [6] [2,5] -3 hSpCas9 positive selection 3825967
72781624 72781647 13 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -1.7220192131951888 [5] [0,0] -9 hSpCas9 positive selection 3825968
72781793 72781816 13 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GTTCTTAAAAAAGACCCGGGCGG DIS3 ENSG00000083520 -1.1888637879921433 [4] [0,1] -9 hSpCas9 positive selection 3825969
72776028 72776051 13 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CCTTGCTGTAGCTTACTTAAGGG DIS3 ENSG00000083520 -0.588664394797056 [5] [2,2] -6 hSpCas9 positive selection 3825970
72777438 72777461 13 + 26780180 A375 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 1.72982125529719 [] [] 9 hSpCas9 negative selection 3933341
72776028 72776051 13 - 26780180 A375 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 1.41855960759224 [] [] 7 hSpCas9 negative selection 3933342
72778302 72778325 13 - 26780180 A375 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.692516128120052 [] [] 2 hSpCas9 negative selection 3933343
72777421 72777444 13 - 26780180 A375 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 1.49626940549321 [] [] 8 hSpCas9 negative selection 3933344
72776027 72776050 13 + 26780180 A375 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 1.63723076251344 [] [] 8 hSpCas9 negative selection 3933345
72778177 72778200 13 + 26780180 A375 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 1.29790919243138 [] [] 7 hSpCas9 negative selection 3933346
72777438 72777461 13 + 26780180 HT29 viability (GeCKOv2 library) AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 1.88417055213381 [] [] 9 hSpCas9 negative selection 4041307
72776028 72776051 13 - 26780180 HT29 viability (GeCKOv2 library) CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 1.83970283508867 [] [] 8 hSpCas9 negative selection 4041308
72778302 72778325 13 - 26780180 HT29 viability (GeCKOv2 library) CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.830225452194078 [] [] 3 hSpCas9 negative selection 4041309
72777421 72777444 13 - 26780180 HT29 viability (GeCKOv2 library) CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.504255654431093 [] [] 1 hSpCas9 negative selection 4041310
72776027 72776050 13 + 26780180 HT29 viability (GeCKOv2 library) GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.205260059417346 [] [] 0 hSpCas9 negative selection 4041311
72778177 72778200 13 + 26780180 HT29 viability (GeCKOv2 library) TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 2.06216761801541 [] [] 9 hSpCas9 negative selection 4041312
72777438 72777461 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.027492256062857434 [3] [2,1] 0 hSpCas9 positive selection 4132298
72778177 72778200 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.7699828334088217 [2] [0,0] -9 hSpCas9 positive selection 4132299
72778244 72778267 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 0.10543718400348416 [3] [2,2] 2 hSpCas9 positive selection 4132300
72777438 72777461 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.9823871680660426 [4] [0,0,0,0] -9 hSpCas9 positive selection 4196320
72778177 72778200 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.6371141398436477 [2] [0,0,0,0] -8 hSpCas9 positive selection 4196321
72778244 72778267 13 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTATGAAGATAACTTGCAGCTGG DIS3 ENSG00000083520 -0.15154297056283988 [3] [0,3,0,0] -2 hSpCas9 positive selection 4196322
72778302 72778325 13 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.4191455141370813 [1] [1,1] 8 hSpCas9 positive selection 4266960
72776027 72776050 13 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.3383044506837595 [3] [2,1] -6 hSpCas9 positive selection 4266961
72776028 72776051 13 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.1804923372434457 [1] [1,0] -4 hSpCas9 positive selection 4266962
72777438 72777461 13 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.13335289268555425 [2] [2,1] -3 hSpCas9 positive selection 4331230
72778177 72778200 13 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.8689644255730138 [1] [0,0] -9 hSpCas9 positive selection 4331231
72777421 72777444 13 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 -0.12197768140931597 [2] [2,1] -2 hSpCas9 positive selection 4331232
72773755 72773777 13 - 27760321 OCIAML3 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -2.1493780345629627 [176,151] [1,63] -9 hSpCas9 negative selection 4394776
72773944 72773966 13 + 27760321 OCIAML3 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 0.11168982291882618 [381,321] [324,258] 1 hSpCas9 negative selection 4394777
72775315 72775337 13 - 27760321 OCIAML3 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -0.6179087324023339 [692,559] [330,299] -6 hSpCas9 negative selection 4394778
72775982 72776004 13 - 27760321 OCIAML3 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 0.2353317592838013 [284,262] [276,219] 2 hSpCas9 negative selection 4394779
72781604 72781626 13 - 27760321 OCIAML3 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.0545476894932624 [368,342] [104,171] -7 hSpCas9 negative selection 4394780
72773755 72773777 13 - 27760321 OCIAML2 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -1.6580796777047906 [176,151] [35,49] -8 hSpCas9 negative selection 4478239
72773944 72773966 13 + 27760321 OCIAML2 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.17530934783294339 [381,321] [195,323] -2 hSpCas9 negative selection 4478240
72775315 72775337 13 - 27760321 OCIAML2 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -1.0286345219040867 [692,559] [193,316] -7 hSpCas9 negative selection 4478241
72775982 72776004 13 - 27760321 OCIAML2 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 0.3942769882215711 [284,262] [286,296] 5 hSpCas9 negative selection 4478242
72781604 72781626 13 - 27760321 OCIAML2 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.002197312742519 [368,342] [107,190] -7 hSpCas9 negative selection 4478243
72773755 72773777 13 - 27760321 MV411 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -2.481148069516961 [176,151] [0,46] -9 hSpCas9 negative selection 4561702
72773944 72773966 13 + 27760321 MV411 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.5159266861909726 [381,321] [214,81] -4 hSpCas9 negative selection 4561703
72775315 72775337 13 - 27760321 MV411 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -3.6222345694775284 [692,559] [22,48] -9 hSpCas9 negative selection 4561704
72775982 72776004 13 - 27760321 MV411 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -0.5124809088451868 [284,262] [67,214] -4 hSpCas9 negative selection 4561705
72781604 72781626 13 - 27760321 MV411 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 0.4323916311059288 [368,342] [454,109] 3 hSpCas9 negative selection 4561706
72773755 72773777 13 - 27760321 HL60 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -4.381772238061329 [176,151] [3,8] -9 hSpCas9 negative selection 4645165
72773944 72773966 13 + 27760321 HL60 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.20798859560804872 [381,321] [264,229] -2 hSpCas9 negative selection 4645166
72775315 72775337 13 - 27760321 HL60 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -0.6186160174098342 [692,559] [281,383] -6 hSpCas9 negative selection 4645167
72775982 72776004 13 - 27760321 HL60 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 0.11549685841935453 [284,262] [191,295] 1 hSpCas9 negative selection 4645168
72781604 72781626 13 - 27760321 HL60 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.094037540015234 [368,342] [55,80] -9 hSpCas9 negative selection 4645169
72773755 72773777 13 - 27760321 HT1080 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -5.754609744218425 [151,118] [0,0] -8 hSpCas9 negative selection 4728628
72773944 72773966 13 + 27760321 HT1080 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -3.190809220814535 [321,250] [22,0] -7 hSpCas9 negative selection 4728629
72775315 72775337 13 - 27760321 HT1080 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -1.461672196069343 [559,436] [10,138] -5 hSpCas9 negative selection 4728630
72775982 72776004 13 - 27760321 HT1080 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -3.3541937582148433 [262,204] [0,17] -7 hSpCas9 negative selection 4728631
72781604 72781626 13 - 27760321 HT1080 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -6.364298340994989 [342,267] [0,1] -9 hSpCas9 negative selection 4728632
72773755 72773777 13 - 27760321 HT29 viability after 7 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -0.7593701816694176 [151,118] [107,117,83] -8 hSpCas9 negative selection 4812091
72773944 72773966 13 + 27760321 HT29 viability after 7 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 0.3074626865649894 [321,250] [399,412,542] 5 hSpCas9 negative selection 4812092
72775315 72775337 13 - 27760321 HT29 viability after 7 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -0.050451910810826894 [559,436] [597,482,766] 0 hSpCas9 negative selection 4812093
72775982 72776004 13 - 27760321 HT29 viability after 7 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 0.3122250473915468 [262,204] [397,303,419] 5 hSpCas9 negative selection 4812094
72781604 72781626 13 - 27760321 HT29 viability after 7 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -0.48450920981485507 [342,267] [280,314,246] -6 hSpCas9 negative selection 4812095
72773755 72773777 13 - 27760321 HT29 viability after 25 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -1.8054136215494567 [151,118] [21,9,108] -8 hSpCas9 negative selection 4895554
72773944 72773966 13 + 27760321 HT29 viability after 25 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.882639076814353 [321,250] [189,186,151] -6 hSpCas9 negative selection 4895555
72775315 72775337 13 - 27760321 HT29 viability after 25 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -2.3516156655515696 [559,436] [178,34,116] -8 hSpCas9 negative selection 4895556
72775982 72776004 13 - 27760321 HT29 viability after 25 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -2.0865829388669703 [262,204] [79,67,36] -8 hSpCas9 negative selection 4895557
72781604 72781626 13 - 27760321 HT29 viability after 25 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -6.208983917332155 [342,267] [0,11,0] -9 hSpCas9 negative selection 4895558
72773755 72773777 13 - 27760321 HT29 viability after 22 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -2.305052118706592 [151,118] [14,2,77] -8 hSpCas9 negative selection 4979017
72773944 72773966 13 + 27760321 HT29 viability after 22 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.7651232529885554 [321,250] [221,152,208] -6 hSpCas9 negative selection 4979018
72775315 72775337 13 - 27760321 HT29 viability after 22 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -3.182937117766182 [559,436] [34,106,48] -8 hSpCas9 negative selection 4979019
72775982 72776004 13 - 27760321 HT29 viability after 22 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -1.315026773177669 [262,204] [133,130,59] -7 hSpCas9 negative selection 4979020
72781604 72781626 13 - 27760321 HT29 viability after 22 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -8.464312765588284 [342,267] [0,0,0] -9 hSpCas9 negative selection 4979021
72773755 72773777 13 - 27760321 HT29 viability after 19 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -3.353701651606551 [151,118] [0,27,14] -9 hSpCas9 negative selection 5062480
72773944 72773966 13 + 27760321 HT29 viability after 19 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -1.1217400949437257 [321,250] [380,85,13] -7 hSpCas9 negative selection 5062481
72775315 72775337 13 - 27760321 HT29 viability after 19 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -2.9119260570471432 [559,436] [212,17,12] -8 hSpCas9 negative selection 5062482
72775982 72776004 13 - 27760321 HT29 viability after 19 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -0.6913859725305695 [262,204] [215,85,198] -5 hSpCas9 negative selection 5062483
72781604 72781626 13 - 27760321 HT29 viability after 19 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -8.44847271316507 [342,267] [0,0,0] -9 hSpCas9 negative selection 5062484
72773755 72773777 13 - 27760321 HT29 viability after 16 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -3.3717099870358407 [151,118] [23,7,12] -9 hSpCas9 negative selection 5145943
72773944 72773966 13 + 27760321 HT29 viability after 16 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.9839481252663749 [321,250] [190,79,219] -7 hSpCas9 negative selection 5145944
72775315 72775337 13 - 27760321 HT29 viability after 16 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -2.042914857130265 [559,436] [83,217,96] -8 hSpCas9 negative selection 5145945
72775982 72776004 13 - 27760321 HT29 viability after 16 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -1.4943045562632147 [262,204] [122,76,81] -8 hSpCas9 negative selection 5145946
72781604 72781626 13 - 27760321 HT29 viability after 16 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.9411183937139533 [342,267] [0,59,67] -9 hSpCas9 negative selection 5145947
72773755 72773777 13 - 27760321 HT29 viability after 13 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -2.1952706810020572 [151,118] [9,57,34] -9 hSpCas9 negative selection 5229406
72773944 72773966 13 + 27760321 HT29 viability after 13 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.7485474998061685 [321,250] [205,148,235] -7 hSpCas9 negative selection 5229407
72775315 72775337 13 - 27760321 HT29 viability after 13 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -1.5596225203356353 [559,436] [311,126,151] -8 hSpCas9 negative selection 5229408
72775982 72776004 13 - 27760321 HT29 viability after 13 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -0.42492837549420437 [262,204] [273,157,175] -5 hSpCas9 negative selection 5229409
72781604 72781626 13 - 27760321 HT29 viability after 13 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.335271289808981 [342,267] [48,129,33] -9 hSpCas9 negative selection 5229410
72773755 72773777 13 - 27760321 HT29 viability after 10 days ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -1.1696832445152745 [151,118] [104,28,89] -8 hSpCas9 negative selection 5312869
72773944 72773966 13 + 27760321 HT29 viability after 10 days ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 -0.13674546222292389 [321,250] [240,423,313] -2 hSpCas9 negative selection 5312870
72775315 72775337 13 - 27760321 HT29 viability after 10 days CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 -0.6890918097511185 [559,436] [588,233,331] -7 hSpCas9 negative selection 5312871
72775982 72776004 13 - 27760321 HT29 viability after 10 days AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -0.28291515143396717 [262,204] [322,296,104] -4 hSpCas9 negative selection 5312872
72781604 72781626 13 - 27760321 HT29 viability after 10 days ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -1.319162585028199 [342,267] [100,183,173] -8 hSpCas9 negative selection 5312873
72773755 72773777 13 - 27760321 MOLM13 viability ATTCGCATAGAAACCAGACAGG DIS3 ENSG00000083520 -0.53965664943604 [176,151] [0,116] -3 hSpCas9 negative selection 5396332
72773944 72773966 13 + 27760321 MOLM13 viability ACCTCCTTAATGTCAGACTTGG DIS3 ENSG00000083520 0.08962069386596502 [381,321] [209,210] 0 hSpCas9 negative selection 5396333
72775315 72775337 13 - 27760321 MOLM13 viability CACGAAGATATTGTGGCTGTGG DIS3 ENSG00000083520 0.07375306514694546 [692,559] [6,678] 0 hSpCas9 negative selection 5396334
72775982 72776004 13 - 27760321 MOLM13 viability AGGAACATTTAGAGCTAGCAGG DIS3 ENSG00000083520 -1.7646128950418283 [284,262] [58,33] -7 hSpCas9 negative selection 5396335
72781604 72781626 13 - 27760321 MOLM13 viability ACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -3.245594571965416 [368,342] [11,28] -9 hSpCas9 negative selection 5396336
72781624 72781647 13 + 27661255 K562 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -1.1465789619889646 [1259,1252] [474,434] -8 dCas9-KRAB negative selection 5475122
72781554 72781577 13 - 27661255 K562 viability GCGGCCCCACGGGGACAAGGGGG DIS3 ENSG00000083520 -0.22117031837012024 [561,476] [342,368] -6 dCas9-KRAB negative selection 5475123
72778302 72778325 13 - 27260156 BXPC3 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.07357814482374603 [118] [69,76,130,213] -2 hSpCas9 negative selection 5539420
72776027 72776050 13 + 27260156 BXPC3 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.3633796757478603 [761] [552,659,663,598] -7 hSpCas9 negative selection 5539421
72776028 72776051 13 - 27260156 BXPC3 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.003475328463702 [181] [67,58,91,174] -9 hSpCas9 negative selection 5539422
72777438 72777461 13 + 27260156 BXPC3 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.764037108726338 [357] [188,237,125,342] -9 hSpCas9 negative selection 5603690
72778177 72778200 13 + 27260156 BXPC3 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.3755965217332966 [152] [64,43,60,78] -9 hSpCas9 negative selection 5603691
72777421 72777444 13 - 27260156 BXPC3 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.14160251103379456 [345] [329,388,395,498] 3 hSpCas9 negative selection 5603692
72778302 72778325 13 - 27260156 A673 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.2816246932451063 [118] [139,143,103,81] -6 hSpCas9 negative selection 5660671
72776027 72776050 13 + 27260156 A673 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.3084644877400398 [761] [911,641,710,709] -6 hSpCas9 negative selection 5660672
72776028 72776051 13 - 27260156 A673 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.8104303272787314 [181] [71,100,122,200] -9 hSpCas9 negative selection 5660673
72777438 72777461 13 + 27260156 A673 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.7240292052071442 [357] [347,259,259,177] -9 hSpCas9 negative selection 5724941
72778177 72778200 13 + 27260156 A673 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.7547790975811492 [152] [170,62,125,81] -9 hSpCas9 negative selection 5724942
72777421 72777444 13 - 27260156 A673 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.4178476644927045 [345] [660,535,543,486] 8 hSpCas9 negative selection 5724943
72778302 72778325 13 - 27260156 A375 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.28668003594011515 [118] [200,69,93,87] -4 hSpCas9 negative selection 5781922
72776027 72776050 13 + 27260156 A375 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.9912849941280746 [761] [355,624,420,414] -8 hSpCas9 negative selection 5781923
72776028 72776051 13 - 27260156 A375 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.9057466099799565 [181] [128,61,35,6] -9 hSpCas9 negative selection 5781924
72777438 72777461 13 + 27260156 A375 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -2.142343921839023 [357] [156,92,45,83] -9 hSpCas9 negative selection 5846192
72778177 72778200 13 + 27260156 A375 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.4553922090841318 [152] [42,52,119,44] -9 hSpCas9 negative selection 5846193
72777421 72777444 13 - 27260156 A375 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.40117660227271174 [345] [718,407,524,471] 6 hSpCas9 negative selection 5846194
72778302 72778325 13 - 27260156 COLO741 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.16524267812733218 [118] [140,145,217] 3 hSpCas9 negative selection 5903173
72776027 72776050 13 + 27260156 COLO741 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.2775647512173987 [761] [824,883,707] -5 hSpCas9 negative selection 5903174
72776028 72776051 13 - 27260156 COLO741 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.8599512621774914 [181] [83,35,72] -9 hSpCas9 negative selection 5903175
72777438 72777461 13 + 27260156 COLO741 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.6898637397830558 [357] [313,288,251] -8 hSpCas9 negative selection 5967443
72778177 72778200 13 + 27260156 COLO741 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.7024828407634829 [152] [148,141,74] -9 hSpCas9 negative selection 5967444
72777421 72777444 13 - 27260156 COLO741 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.37132814097765116 [345] [528,501,671] 7 hSpCas9 negative selection 5967445
72778302 72778325 13 - 27260156 CAL120 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.3954676042861083 [118] [132,136,302] 6 hSpCas9 negative selection 6024424
72776027 72776050 13 + 27260156 CAL120 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.43250751959625106 [761] [681,583,835] -6 hSpCas9 negative selection 6024425
72776028 72776051 13 - 27260156 CAL120 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.470111968482213 [181] [79,35,12] -9 hSpCas9 negative selection 6024426
72777438 72777461 13 + 27260156 CAL120 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.8406603411816853 [357] [343,139,275] -8 hSpCas9 negative selection 6088694
72778177 72778200 13 + 27260156 CAL120 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.3544322073621784 [152] [72,197,163] -5 hSpCas9 negative selection 6088695
72777421 72777444 13 - 27260156 CAL120 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.32071782807259486 [345] [581,629,409] 5 hSpCas9 negative selection 6088696
72778302 72778325 13 - 27260156 CADOES1 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.27015404133673737 [118] [163,118,136,112] 4 hSpCas9 negative selection 6145675
72776027 72776050 13 + 27260156 CADOES1 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.2872785827325689 [761] [595,476,635,614] -5 hSpCas9 negative selection 6145676
72776028 72776051 13 - 27260156 CADOES1 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.254214881449649 [181] [29,77,52,124] -9 hSpCas9 negative selection 6145677
72777438 72777461 13 + 27260156 CADOES1 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.029479320283312 [357] [152,186,111,201] -9 hSpCas9 negative selection 6209945
72778177 72778200 13 + 27260156 CADOES1 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.3343769116239608 [152] [56,94,37,34] -9 hSpCas9 negative selection 6209946
72777421 72777444 13 - 27260156 CADOES1 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.424588531117558 [345] [380,441,467,436] 7 hSpCas9 negative selection 6209947
72778302 72778325 13 - 27260156 EWS502 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.0876197481076686 [118] [45,166,153,113] -1 hSpCas9 negative selection 6266926
72776027 72776050 13 + 27260156 EWS502 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.34197775972872607 [761] [622,661,414,857] -5 hSpCas9 negative selection 6266927
72776028 72776051 13 - 27260156 EWS502 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.235240137290664 [181] [5,31,10,34] -9 hSpCas9 negative selection 6266928
72777438 72777461 13 + 27260156 EWS502 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.7841025412432043 [357] [133,330,177,243] -8 hSpCas9 negative selection 6331196
72778177 72778200 13 + 27260156 EWS502 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.6021335177848715 [152] [40,86,33,50] -9 hSpCas9 negative selection 6331197
72777421 72777444 13 - 27260156 EWS502 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.6111579797176587 [345] [746,495,488,477] 9 hSpCas9 negative selection 6331198
72778302 72778325 13 - 27260156 EW8 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.1169573666497632 [118] [72,96,130,108] 2 hSpCas9 negative selection 6388177
72776027 72776050 13 + 27260156 EW8 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.5570406190642362 [761] [653,295,342,422] -7 hSpCas9 negative selection 6388178
72776028 72776051 13 - 27260156 EW8 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.5522516448899744 [181] [25,7,15,51] -9 hSpCas9 negative selection 6388179
72777438 72777461 13 + 27260156 EW8 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.5764021799062247 [357] [243,165,110,275] -8 hSpCas9 negative selection 6452447
72778177 72778200 13 + 27260156 EW8 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.9691173859835278 [152] [76,71,43,64] -9 hSpCas9 negative selection 6452448
72777421 72777444 13 - 27260156 EW8 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.7874690161764113 [345] [493,418,430,599] 9 hSpCas9 negative selection 6452449
72778302 72778325 13 - 27260156 CORL105 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.24756033567152103 [118] [112,103,164,94] -4 hSpCas9 negative selection 6509428
72776027 72776050 13 + 27260156 CORL105 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.6575095220997461 [761] [578,507,581,596] -8 hSpCas9 negative selection 6509429
72776028 72776051 13 - 27260156 CORL105 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.489313124206086 [181] [61,81,38,113] -9 hSpCas9 negative selection 6509430
72777438 72777461 13 + 27260156 CORL105 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.6510291535853232 [357] [290,374,230,163] -8 hSpCas9 negative selection 6573698
72778177 72778200 13 + 27260156 CORL105 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.144156501623477 [152] [88,59,94,82] -9 hSpCas9 negative selection 6573699
72777421 72777444 13 - 27260156 CORL105 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.3088932168406696 [345] [518,510,542,440] 6 hSpCas9 negative selection 6573700
72778302 72778325 13 - 27260156 HS294T viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.592778905788035 [118] [28,39,25,25] -7 hSpCas9 negative selection 6630679
72776027 72776050 13 + 27260156 HS294T viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.4966677263556566 [761] [160,191,256,233] -6 hSpCas9 negative selection 6630680
72776028 72776051 13 - 27260156 HS294T viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.0854349145486726 [181] [7,11,21,26] -9 hSpCas9 negative selection 6630681
72777438 72777461 13 + 27260156 HS294T viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.1903195640571147 [357] [30,56,78,81] -9 hSpCas9 negative selection 6694949
72778177 72778200 13 + 27260156 HS294T viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.003023148487746 [152] [14,42,20,41] -8 hSpCas9 negative selection 6694950
72777421 72777444 13 - 27260156 HS294T viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.30088282305615754 [345] [132,216,154,152] 4 hSpCas9 negative selection 6694951
72778302 72778325 13 - 27260156 HCC44 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.019097447436319914 [118] [120,53,149,228] 0 hSpCas9 negative selection 6751930
72776027 72776050 13 + 27260156 HCC44 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.2555734254393738 [761] [701,677,861,669] -4 hSpCas9 negative selection 6751931
72776028 72776051 13 - 27260156 HCC44 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.0177148175992117 [181] [83,59,40,18] -9 hSpCas9 negative selection 6751932
72777438 72777461 13 + 27260156 HCC44 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.8912944321829424 [357] [230,169,217,258] -8 hSpCas9 negative selection 6816200
72778177 72778200 13 + 27260156 HCC44 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.7743824333991622 [152] [52,60,54,32] -9 hSpCas9 negative selection 6816201
72777421 72777444 13 - 27260156 HCC44 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.32249278578832924 [345] [659,255,625,483] 5 hSpCas9 negative selection 6816202
72778302 72778325 13 - 27260156 G402 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.3641486494157058 [118] [361,119,93,191] 4 hSpCas9 negative selection 6873181
72776027 72776050 13 + 27260156 G402 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.8639771520722196 [761] [676,387,602,395] -7 hSpCas9 negative selection 6873182
72776028 72776051 13 - 27260156 G402 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.6914299811437696 [181] [18,81,3,32] -9 hSpCas9 negative selection 6873183
72777438 72777461 13 + 27260156 G402 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.408015383487042 [357] [86,183,111,259] -9 hSpCas9 negative selection 6937451
72778177 72778200 13 + 27260156 G402 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.0602434992317404 [152] [139,110,82,34] -8 hSpCas9 negative selection 6937452
72777421 72777444 13 - 27260156 G402 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.9582329868953513 [345] [949,664,1113,570] 9 hSpCas9 negative selection 6937453
72778302 72778325 13 - 27260156 L33 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.6567220273804375 [118] [70,37,26,94] -9 hSpCas9 negative selection 6994432
72776027 72776050 13 + 27260156 L33 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.23717274874793193 [761] [798,358,655,876] 5 hSpCas9 negative selection 6994433
72776028 72776051 13 - 27260156 L33 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.367434903853919 [181] [72,30,21,97] -9 hSpCas9 negative selection 6994434
72777438 72777461 13 + 27260156 L33 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.22282710431261582 [357] [370,104,203,273] -5 hSpCas9 negative selection 7058702
72778177 72778200 13 + 27260156 L33 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.433624350766012 [152] [140,48,51,108] -8 hSpCas9 negative selection 7058703
72777421 72777444 13 - 27260156 L33 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.22613143959450818 [345] [357,140,307,427] 5 hSpCas9 negative selection 7058704
72778302 72778325 13 - 27260156 K562 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.3139600634577737 [118] [204,127,165,41] 4 hSpCas9 negative selection 7115683
72776027 72776050 13 + 27260156 K562 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.33535969563551465 [761] [561,379,699,497] -4 hSpCas9 negative selection 7115684
72776028 72776051 13 - 27260156 K562 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.7751370176055956 [181] [3,4,23,12] -9 hSpCas9 negative selection 7115685
72777438 72777461 13 + 27260156 K562 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.3061653063302314 [357] [186,258,25,60] -8 hSpCas9 negative selection 7179953
72778177 72778200 13 + 27260156 K562 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -2.4676677712056483 [152] [11,11,62,10] -9 hSpCas9 negative selection 7179954
72777421 72777444 13 - 27260156 K562 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.4357681882940343 [345] [428,590,414,253] 5 hSpCas9 negative selection 7179955
72778302 72778325 13 - 27260156 HT29 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.16981505410371178 [118] [234,128,193,101] 3 hSpCas9 negative selection 7236934
72776027 72776050 13 + 27260156 HT29 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.45264461388026733 [761] [565,834,696,616] -7 hSpCas9 negative selection 7236935
72776028 72776051 13 - 27260156 HT29 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.4519700617814038 [181] [38,77,46,4] -9 hSpCas9 negative selection 7236936
72777438 72777461 13 + 27260156 HT29 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.9688395524646292 [357] [175,205,360,148] -8 hSpCas9 negative selection 7301204
72778177 72778200 13 + 27260156 HT29 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.9173107396244407 [152] [101,42,93,143] -8 hSpCas9 negative selection 7301205
72777421 72777444 13 - 27260156 HT29 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.4088434400251674 [345] [578,604,446,598] 7 hSpCas9 negative selection 7301206
72778302 72778325 13 - 27260156 MHHES1 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.042591661573311734 [118] [141,159,189,74] 0 hSpCas9 negative selection 7358185
72776027 72776050 13 + 27260156 MHHES1 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.5203864510899884 [761] [712,857,433,448] -7 hSpCas9 negative selection 7358186
72776028 72776051 13 - 27260156 MHHES1 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.665882656293976 [181] [118,69,26,50] -9 hSpCas9 negative selection 7358187
72777438 72777461 13 + 27260156 MHHES1 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.815167975386538 [357] [184,278,197,244] -9 hSpCas9 negative selection 7422455
72778177 72778200 13 + 27260156 MHHES1 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.1262277704850263 [152] [86,73,107,51] -9 hSpCas9 negative selection 7422456
72777421 72777444 13 - 27260156 MHHES1 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.2513675863827314 [345] [556,466,359,469] 4 hSpCas9 negative selection 7422457
72778302 72778325 13 - 27260156 MEWO viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.22985292916931965 [118] [176,29,93] -5 hSpCas9 negative selection 7479436
72776027 72776050 13 + 27260156 MEWO viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.33809228925185963 [761] [604,505,588] -6 hSpCas9 negative selection 7479437
72776028 72776051 13 - 27260156 MEWO viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.041363090892433 [181] [45,37,40] -9 hSpCas9 negative selection 7479438
72777438 72777461 13 + 27260156 MEWO viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.8026976480571824 [357] [180,160,231] -9 hSpCas9 negative selection 7543706
72778177 72778200 13 + 27260156 MEWO viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.5905588603751541 [152] [94,123,65] -8 hSpCas9 negative selection 7543707
72777421 72777444 13 - 27260156 MEWO viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.6214141500420476 [345] [731,327,479] 9 hSpCas9 negative selection 7543708
72778302 72778325 13 - 27260156 LNCAPCLONEFGC viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.15386439070993707 [118] [88,72,128,102] -2 hSpCas9 negative selection 7600687
72776027 72776050 13 + 27260156 LNCAPCLONEFGC viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.43858023099132093 [761] [432,528,757,353] -6 hSpCas9 negative selection 7600688
72776028 72776051 13 - 27260156 LNCAPCLONEFGC viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.4022265935920504 [181] [4,18,19,18] -9 hSpCas9 negative selection 7600689
72777438 72777461 13 + 27260156 LNCAPCLONEFGC viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.419804924309516 [357] [112,137,135,98] -9 hSpCas9 negative selection 7664957
72778177 72778200 13 + 27260156 LNCAPCLONEFGC viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.7312097903319665 [152] [72,107,59,87] -8 hSpCas9 negative selection 7664958
72777421 72777444 13 - 27260156 LNCAPCLONEFGC viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.21175069153263343 [345] [458,341,226,402] 3 hSpCas9 negative selection 7664959
72778302 72778325 13 - 27260156 PANC0327 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.9919407519968686 [118] [63,48,46,53] -8 hSpCas9 negative selection 7721938
72776027 72776050 13 + 27260156 PANC0327 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.9335136942547791 [761] [436,277,289,428] -8 hSpCas9 negative selection 7721939
72776028 72776051 13 - 27260156 PANC0327 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.7192451285347627 [181] [9,26,3,5] -9 hSpCas9 negative selection 7721940
72777438 72777461 13 + 27260156 PANC0327 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.03591526139347123 [357] [183,182,484,394] 0 hSpCas9 negative selection 7786208
72778177 72778200 13 + 27260156 PANC0327 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.8450612127893986 [152] [105,13,59,132] -8 hSpCas9 negative selection 7786209
72777421 72777444 13 - 27260156 PANC0327 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.1472896550042404 [345] [283,345,304,420] 2 hSpCas9 negative selection 7786210
72778302 72778325 13 - 27260156 NCIH2009 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.49047806355545487 [118] [80,142,122] -6 hSpCas9 negative selection 7843189
72776027 72776050 13 + 27260156 NCIH2009 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -1.2627263086436422 [761] [402,403,515] -8 hSpCas9 negative selection 7843190
72776028 72776051 13 - 27260156 NCIH2009 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.63865753138124 [181] [24,26,9] -9 hSpCas9 negative selection 7843191
72777438 72777461 13 + 27260156 NCIH2009 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.8152768016129195 [357] [128,116,177] -9 hSpCas9 negative selection 7907459
72778177 72778200 13 + 27260156 NCIH2009 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.8227170329765585 [152] [35,79,59] -9 hSpCas9 negative selection 7907460
72777421 72777444 13 - 27260156 NCIH2009 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.31530668273132934 [345] [638,595,575] 4 hSpCas9 negative selection 7907461
72778302 72778325 13 - 27260156 NCIH1373 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.6166246507458177 [118] [404,34,45,103] 6 hSpCas9 negative selection 7964440
72776027 72776050 13 + 27260156 NCIH1373 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.48719462765030586 [761] [365,653,828,139] -5 hSpCas9 negative selection 7964441
72776028 72776051 13 - 27260156 NCIH1373 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -3.323574731801711 [181] [3,30,12,7] -9 hSpCas9 negative selection 7964442
72777438 72777461 13 + 27260156 NCIH1373 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -3.043145670938486 [357] [75,57,35,6] -9 hSpCas9 negative selection 8028710
72778177 72778200 13 + 27260156 NCIH1373 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.6805357385322683 [152] [29,10,13,43] -9 hSpCas9 negative selection 8028711
72777421 72777444 13 - 27260156 NCIH1373 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.41665044845404897 [345] [631,705,278,117] 4 hSpCas9 negative selection 8028712
72778302 72778325 13 - 27260156 PATU8902 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.007978266829193892 [118] [228,101,245,52] 0 hSpCas9 negative selection 8085691
72776027 72776050 13 + 27260156 PATU8902 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -1.6304913801926837 [761] [657,280,155,313] -8 hSpCas9 negative selection 8085692
72776028 72776051 13 - 27260156 PATU8902 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.2934245348988638 [181] [66,5,37,104] -9 hSpCas9 negative selection 8085693
72777438 72777461 13 + 27260156 PATU8902 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -2.4323398461242527 [357] [40,70,180,47] -9 hSpCas9 negative selection 8149961
72778177 72778200 13 + 27260156 PATU8902 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.9059854668392806 [152] [124,213,8,135] -7 hSpCas9 negative selection 8149962
72777421 72777444 13 - 27260156 PATU8902 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.624159312090437 [345] [1026,713,570,686] 6 hSpCas9 negative selection 8149963
72778302 72778325 13 - 27260156 PANC1 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.6592716660739713 [118] [57,56,86,55] -7 hSpCas9 negative selection 8206942
72776027 72776050 13 + 27260156 PANC1 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.6375444926913838 [761] [457,540,407,310] -7 hSpCas9 negative selection 8206943
72776028 72776051 13 - 27260156 PANC1 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.9679705506487646 [181] [30,18,21,8] -9 hSpCas9 negative selection 8206944
72777438 72777461 13 + 27260156 PANC1 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.2937913810521835 [357] [154,119,185,49] -9 hSpCas9 negative selection 8271212
72778177 72778200 13 + 27260156 PANC1 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.3771008718388116 [152] [53,65,43,41] -9 hSpCas9 negative selection 8271213
72777421 72777444 13 - 27260156 PANC1 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.2936997993067817 [345] [276,461,329,397] 5 hSpCas9 negative selection 8271214
72778302 72778325 13 - 27260156 PANC0813 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.4127830928301448 [118] [132,67,107,112] -6 hSpCas9 negative selection 8328193
72776027 72776050 13 + 27260156 PANC0813 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.4873704470861423 [761] [990,605,621,380] -6 hSpCas9 negative selection 8328194
72776028 72776051 13 - 27260156 PANC0813 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.6188997054873209 [181] [63,78,34,97] -9 hSpCas9 negative selection 8328195
72777438 72777461 13 + 27260156 PANC0813 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.26627042912598 [357] [199,181,226,96] -9 hSpCas9 negative selection 8392463
72778177 72778200 13 + 27260156 PANC0813 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.2597284604548997 [152] [55,51,88,99] -9 hSpCas9 negative selection 8392464
72777421 72777444 13 - 27260156 PANC0813 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.2366973214379828 [345] [535,478,463,442] 4 hSpCas9 negative selection 8392465
72778302 72778325 13 - 27260156 RDES viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.3847501264738007 [118] [171,83,230,244] 6 hSpCas9 negative selection 8449444
72776027 72776050 13 + 27260156 RDES viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.35389542117283856 [761] [803,1123,1181,1459] 5 hSpCas9 negative selection 8449445
72776028 72776051 13 - 27260156 RDES viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.47835708733462257 [181] [146,173,142,125] -7 hSpCas9 negative selection 8449446
72777438 72777461 13 + 27260156 RDES viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.27943898033512254 [357] [259,406,418,261] -5 hSpCas9 negative selection 8513714
72778177 72778200 13 + 27260156 RDES viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.6278333330161516 [152] [92,140,63,160] -8 hSpCas9 negative selection 8513715
72777421 72777444 13 - 27260156 RDES viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.6963812787147972 [345] [495,552,777,803] 9 hSpCas9 negative selection 8513716
72778302 72778325 13 - 27260156 PC3 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.24538231506972719 [118] [44,218,111,34] -5 hSpCas9 negative selection 8570695
72776027 72776050 13 + 27260156 PC3 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.20194820413755576 [761] [610,618,1449,1085] 4 hSpCas9 negative selection 8570696
72776028 72776051 13 - 27260156 PC3 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.1776936934910966 [181] [14,84,170,111] -9 hSpCas9 negative selection 8570697
72777438 72777461 13 + 27260156 PC3 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.4177296094402953 [357] [137,212,581,297] -7 hSpCas9 negative selection 8634965
72778177 72778200 13 + 27260156 PC3 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 0.2654074803863442 [152] [89,208,207,263] 6 hSpCas9 negative selection 8634966
72777421 72777444 13 - 27260156 PC3 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.4118502034182318 [345] [281,443,858,439] 8 hSpCas9 negative selection 8634967
72778302 72778325 13 - 27260156 PATU8988T viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.22858347100050858 [118] [116,98,133,189] 4 hSpCas9 negative selection 8691946
72776027 72776050 13 + 27260156 PATU8988T viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.44951752251658256 [761] [652,576,297,643] -6 hSpCas9 negative selection 8691947
72776028 72776051 13 - 27260156 PATU8988T viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.579115089943109 [181] [53,25,14,21] -9 hSpCas9 negative selection 8691948
72777438 72777461 13 + 27260156 PATU8988T viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.7795007090001376 [357] [241,248,115,204] -8 hSpCas9 negative selection 8756216
72778177 72778200 13 + 27260156 PATU8988T viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.2387928621702982 [152] [55,153,37,6] -9 hSpCas9 negative selection 8756217
72777421 72777444 13 - 27260156 PATU8988T viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.5037351663648637 [345] [652,459,398,375] 8 hSpCas9 negative selection 8756218
72778302 72778325 13 - 27260156 T47D viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.16401147143203 [118] [140,117,139,227] 3 hSpCas9 negative selection 8813197
72776027 72776050 13 + 27260156 T47D viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.14654389417973646 [761] [986,879,914,1163] 3 hSpCas9 negative selection 8813198
72776028 72776051 13 - 27260156 T47D viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.012967401643379 [181] [77,39,50,41] -9 hSpCas9 negative selection 8813199
72777438 72777461 13 + 27260156 T47D viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.6090745594033897 [357] [330,269,220,272] -8 hSpCas9 negative selection 8877467
72778177 72778200 13 + 27260156 T47D viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.0404753620104759 [152] [69,89,99,85] -9 hSpCas9 negative selection 8877468
72777421 72777444 13 - 27260156 T47D viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.5587193031009128 [345] [610,558,501,710] 9 hSpCas9 negative selection 8877469
72778302 72778325 13 - 27260156 SU8686 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.37806681984569424 [118] [116,127,50,50] -6 hSpCas9 negative selection 8934448
72776027 72776050 13 + 27260156 SU8686 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.4748393696825546 [761] [671,523,380,582] -6 hSpCas9 negative selection 8934449
72776028 72776051 13 - 27260156 SU8686 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -1.8945968040015346 [181] [52,36,49,55] -9 hSpCas9 negative selection 8934450
72777438 72777461 13 + 27260156 SU8686 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -1.6162078355468248 [357] [139,97,104,118] -9 hSpCas9 negative selection 8998718
72778177 72778200 13 + 27260156 SU8686 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -2.3319902077826233 [152] [30,40,30,12] -9 hSpCas9 negative selection 8998719
72777421 72777444 13 - 27260156 SU8686 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 -0.10582725521936509 [345] [248,334,359,338] -2 hSpCas9 negative selection 8998720
72778302 72778325 13 - 27260156 SKES1 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.03753777048791895 [118] [236,34,119,101] 0 hSpCas9 negative selection 9055699
72776027 72776050 13 + 27260156 SKES1 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 0.03474202658510517 [761] [933,1034,617,595] 0 hSpCas9 negative selection 9055700
72776028 72776051 13 - 27260156 SKES1 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.9699841833267016 [181] [88,77,135,66] -9 hSpCas9 negative selection 9055701
72777438 72777461 13 + 27260156 SKES1 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.8287932763037638 [357] [187,216,151,240] -9 hSpCas9 negative selection 9119969
72778177 72778200 13 + 27260156 SKES1 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.7642659045968607 [152] [100,116,68,77] -9 hSpCas9 negative selection 9119970
72777421 72777444 13 - 27260156 SKES1 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.3106018151061892 [345] [450,451,462,355] 6 hSpCas9 negative selection 9119971
72778302 72778325 13 - 27260156 TOV112D viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 -0.28440044175474255 [118] [76,40,212,45] -5 hSpCas9 negative selection 9176950
72776027 72776050 13 + 27260156 TOV112D viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.230411362139733 [761] [475,865,705,592] -4 hSpCas9 negative selection 9176951
72776028 72776051 13 - 27260156 TOV112D viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -2.1186172587313656 [181] [27,15,64,50] -9 hSpCas9 negative selection 9176952
72777438 72777461 13 + 27260156 TOV112D viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.3442911589077438 [357] [361,311,286,184] -6 hSpCas9 negative selection 9241220
72778177 72778200 13 + 27260156 TOV112D viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.29374402470742544 [152] [139,121,136,101] -5 hSpCas9 negative selection 9241221
72777421 72777444 13 - 27260156 TOV112D viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.012510270917998556 [345] [411,359,266,365] 0 hSpCas9 negative selection 9241222
72778302 72778325 13 - 27260156 TC71 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.037692510592338246 [118] [82,193,99,149] 1 hSpCas9 negative selection 9298201
72776027 72776050 13 + 27260156 TC71 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.007561254473066659 [761] [922,823,717,783] 0 hSpCas9 negative selection 9298202
72776028 72776051 13 - 27260156 TC71 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.8291064717978975 [181] [98,78,131,129] -9 hSpCas9 negative selection 9298203
72777438 72777461 13 + 27260156 TC71 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.5480964774710102 [357] [360,171,221,295] -9 hSpCas9 negative selection 9362471
72778177 72778200 13 + 27260156 TC71 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -0.46721072576226397 [152] [122,130,111,107] -8 hSpCas9 negative selection 9362472
72777421 72777444 13 - 27260156 TC71 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.5198205832140975 [345] [482,560,486,602] 9 hSpCas9 negative selection 9362473
72778302 72778325 13 - 27260156 TC32 viability CGATTCGAGTAGCAGCAAAATGG DIS3 ENSG00000083520 0.07334626545662148 [118] [87,109,107,164] 1 hSpCas9 negative selection 9419452
72776027 72776050 13 + 27260156 TC32 viability GCCTTGCTGTAGCTTACTTAAGG DIS3 ENSG00000083520 -0.29937722624805274 [761] [538,411,765,683] -5 hSpCas9 negative selection 9419453
72776028 72776051 13 - 27260156 TC32 viability CCCTTAAGTAAGCTACAGCAAGG DIS3 ENSG00000083520 -0.8733437179942585 [181] [38,108,128,97] -9 hSpCas9 negative selection 9419454
72777438 72777461 13 + 27260156 TC32 viability AGCAAGACGATCTATGAGTTCGG DIS3 ENSG00000083520 -0.856960692183959 [357] [214,88,266,209] -9 hSpCas9 negative selection 9483722
72778177 72778200 13 + 27260156 TC32 viability TTAGACTTACAAGTGAAAGCTGG DIS3 ENSG00000083520 -1.0833192446926974 [152] [46,44,146,52] -9 hSpCas9 negative selection 9483723
72777421 72777444 13 - 27260156 TC32 viability CTTGCTTGTTTGTCTGAAGAAGG DIS3 ENSG00000083520 0.4863550227885017 [345] [430,319,648,484] 8 hSpCas9 negative selection 9483724
72762012 72762035 13 + 27869803 HPAFII viability after 27 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.4927513445726532 [90] [28,6,NaN] -7 hSpCas9 negative selection 9550206
72765979 72766002 13 - 27869803 HPAFII viability after 27 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.3101436207167352 [300] [77,51,NaN] -7 hSpCas9 negative selection 9550207
72772217 72772240 13 - 27869803 HPAFII viability after 27 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.4282285331874363 [46] [0,15,NaN] -7 hSpCas9 negative selection 9550208
72773778 72773801 13 + 27869803 HPAFII viability after 27 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -2.908496428858025 [308] [25,17,NaN] -9 hSpCas9 negative selection 9550209
72780902 72780925 13 + 27869803 HPAFII viability after 27 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -1.6329180904319949 [302] [58,44,NaN] -8 hSpCas9 negative selection 9550210
72781604 72781627 13 - 27869803 HPAFII viability after 27 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -4.917504856759344 [161] [4,0,NaN] -9 hSpCas9 negative selection 9550211
72762012 72762035 13 + 27869803 HPAFII viability after 15 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.799325125222461 [90] [16,34,NaN] -9 hSpCas9 negative selection 9632655
72765979 72766002 13 - 27869803 HPAFII viability after 15 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.059678193670553 [300] [251,94,NaN] -8 hSpCas9 negative selection 9632656
72772217 72772240 13 - 27869803 HPAFII viability after 15 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.4622586140119882 [46] [11,51,NaN] -5 hSpCas9 negative selection 9632657
72773778 72773801 13 + 27869803 HPAFII viability after 15 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.8880375503911702 [308] [303,101,NaN] -7 hSpCas9 negative selection 9632658
72780902 72780925 13 + 27869803 HPAFII viability after 15 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.12207286116405 [302] [66,18,NaN] -9 hSpCas9 negative selection 9632659
72781604 72781627 13 - 27869803 HPAFII viability after 15 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.6006856004281333 [161] [61,7,NaN] -9 hSpCas9 negative selection 9632660
72762012 72762035 13 + 27869803 ASPC1 viability after 36 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -2.1084048710460914 [175] [21,4,15] -9 hSpCas9 negative selection 9715104
72765979 72766002 13 - 27869803 ASPC1 viability after 36 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -0.8456243054000719 [864] [195,256,75] -7 hSpCas9 negative selection 9715105
72772217 72772240 13 - 27869803 ASPC1 viability after 36 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.2307871905070789 [215] [50,23,24] -8 hSpCas9 negative selection 9715106
72773778 72773801 13 + 27869803 ASPC1 viability after 36 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -0.1296148054082896 [553] [165,325,63] -1 hSpCas9 negative selection 9715107
72780902 72780925 13 + 27869803 ASPC1 viability after 36 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -3.2916611313328032 [982] [0,36,56] -9 hSpCas9 negative selection 9715108
72781604 72781627 13 - 27869803 ASPC1 viability after 36 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.413034247751549 [605] [24,71,23] -9 hSpCas9 negative selection 9715109
72762012 72762035 13 + 27869803 PATU8988S viability after 35 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -1.9317098529019936 [179] [19,17,NaN] -9 hSpCas9 negative selection 9797553
72765979 72766002 13 - 27869803 PATU8988S viability after 35 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.3470389409184147 [763] [101,139,NaN] -8 hSpCas9 negative selection 9797554
72772217 72772240 13 - 27869803 PATU8988S viability after 35 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -1.903328101167974 [180] [13,24,NaN] -9 hSpCas9 negative selection 9797555
72773778 72773801 13 + 27869803 PATU8988S viability after 35 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.07431618252098728 [552] [231,236,NaN] 0 hSpCas9 negative selection 9797556
72780902 72780925 13 + 27869803 PATU8988S viability after 35 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.721615647092353 [793] [39,56,NaN] -9 hSpCas9 negative selection 9797557
72781604 72781627 13 - 27869803 PATU8988S viability after 35 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -3.7710088570809877 [574] [0,32,NaN] -9 hSpCas9 negative selection 9797558
72762012 72762035 13 + 27869803 PATU8988S viability after 31 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -3.216581667537758 [179] [12,0,NaN] -9 hSpCas9 negative selection 9880002
72765979 72766002 13 - 27869803 PATU8988S viability after 31 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.217638529111994 [763] [86,186,NaN] -8 hSpCas9 negative selection 9880003
72772217 72772240 13 - 27869803 PATU8988S viability after 31 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -2.7352186383226114 [180] [5,16,NaN] -9 hSpCas9 negative selection 9880004
72773778 72773801 13 + 27869803 PATU8988S viability after 31 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 0.19717382188141755 [552] [243,263,NaN] 2 hSpCas9 negative selection 9880005
72780902 72780925 13 + 27869803 PATU8988S viability after 31 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.620694620737064 [793] [32,74,NaN] -9 hSpCas9 negative selection 9880006
72781604 72781627 13 - 27869803 PATU8988S viability after 31 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -2.4028663538059543 [574] [12,81,NaN] -9 hSpCas9 negative selection 9880007
72762012 72762035 13 + 27869803 HPAFII viability after 35 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -5.525706087202021 [90] [0,0,NaN] -9 hSpCas9 negative selection 9962451
72765979 72766002 13 - 27869803 HPAFII viability after 35 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -2.607674933988302 [300] [24,24,NaN] -8 hSpCas9 negative selection 9962452
72772217 72772240 13 - 27869803 HPAFII viability after 35 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.10222323936464894 [46] [0,45,NaN] 0 hSpCas9 negative selection 9962453
72773778 72773801 13 + 27869803 HPAFII viability after 35 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -1.3197177926108081 [308] [104,14,NaN] -6 hSpCas9 negative selection 9962454
72780902 72780925 13 + 27869803 HPAFII viability after 35 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -4.28262931077239 [302] [5,9,NaN] -9 hSpCas9 negative selection 9962455
72781604 72781627 13 - 27869803 HPAFII viability after 35 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -6.35776144988795 [161] [0,0,NaN] -9 hSpCas9 negative selection 9962456
72762012 72762035 13 + 27869803 HPAFII viability after 31 days AGCTTGCATCATACAGCGAGTGG DIS3 ENSG00000083520 -3.7215574161145333 [90] [0,6,NaN] -9 hSpCas9 negative selection 10044900
72765979 72766002 13 - 27869803 HPAFII viability after 31 days TCCTATAGATCTGCAGACCAAGG DIS3 ENSG00000083520 -1.5793401440567099 [300] [45,67,NaN] -7 hSpCas9 negative selection 10044901
72772217 72772240 13 - 27869803 HPAFII viability after 31 days ATTTGTAGTGTAGACCCACCAGG DIS3 ENSG00000083520 -0.16706737611194367 [46] [0,47,NaN] -1 hSpCas9 negative selection 10044902
72773778 72773801 13 + 27869803 HPAFII viability after 31 days CGAGGGATTCTCTTATCAGCAGG DIS3 ENSG00000083520 -2.5009492445385275 [308] [55,2,NaN] -8 hSpCas9 negative selection 10044903
72780902 72780925 13 + 27869803 HPAFII viability after 31 days TCGGATGCGTTTATATACGGGGG DIS3 ENSG00000083520 -2.423716962922436 [302] [35,26,NaN] -8 hSpCas9 negative selection 10044904
72781604 72781627 13 - 27869803 HPAFII viability after 31 days CACTAATGTGTTACTGCACCAGG DIS3 ENSG00000083520 -6.506478803209367 [161] [0,0,NaN] -9 hSpCas9 negative selection 10044905
72781624 72781647 13 + 28162770 P31FUJ viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -6.434926028244839 [588] [7] -9 hSpCas9 negative selection 10144374
72766022 72766045 13 + 28162770 P31FUJ viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -1.9594258543591259 [277] [83] -8 hSpCas9 negative selection 10144375
72771842 72771865 13 - 28162770 P31FUJ viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.0615307772645495 [237] [66] -8 hSpCas9 negative selection 10144376
72771820 72771843 13 - 28162770 P31FUJ viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -3.7139288941509947 [133] [11] -9 hSpCas9 negative selection 10144377
72761654 72761677 13 + 28162770 P31FUJ viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.5745527176432255 [199] [349] 6 hSpCas9 negative selection 10144378
72781709 72781732 13 - 28162770 P31FUJ viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -2.5353649744348097 [73] [14] -8 hSpCas9 negative selection 10144379
72781699 72781722 13 - 28162770 P31FUJ viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.5598432226953935 [423] [168] -7 hSpCas9 negative selection 10144380
72773735 72773758 13 - 28162770 P31FUJ viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.5165951704149698 [55] [22] -7 hSpCas9 negative selection 10144381
72772708 72772731 13 - 28162770 P31FUJ viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.7046257297847998 [189] [136] -5 hSpCas9 negative selection 10144382
72771085 72771108 13 - 28162770 P31FUJ viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.1845470358071575 [293] [75] -8 hSpCas9 negative selection 10144383
72781624 72781647 13 + 28162770 TF1 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 NaN [NaN] [0] 1 hSpCas9 negative selection 10313740
72766022 72766045 13 + 28162770 TF1 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 NaN [NaN] [71] 1 hSpCas9 negative selection 10313741
72771842 72771865 13 - 28162770 TF1 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 NaN [NaN] [39] 1 hSpCas9 negative selection 10313742
72771820 72771843 13 - 28162770 TF1 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 NaN [NaN] [1] 1 hSpCas9 negative selection 10313743
72761654 72761677 13 + 28162770 TF1 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 NaN [NaN] [86] 1 hSpCas9 negative selection 10313744
72781709 72781732 13 - 28162770 TF1 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 NaN [NaN] [9] 1 hSpCas9 negative selection 10313745
72781699 72781722 13 - 28162770 TF1 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 NaN [NaN] [48] 1 hSpCas9 negative selection 10313746
72773735 72773758 13 - 28162770 TF1 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 NaN [NaN] [0] 1 hSpCas9 negative selection 10313747
72772708 72772731 13 - 28162770 TF1 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 NaN [NaN] [55] 1 hSpCas9 negative selection 10313748
72771085 72771108 13 - 28162770 TF1 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 NaN [NaN] [6] 1 hSpCas9 negative selection 10313749
72781624 72781647 13 + 28162770 SKM1 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -5.281433316659303 [175] [7] -9 hSpCas9 negative selection 10483106
72766022 72766045 13 + 28162770 SKM1 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -0.3674358345565242 [53] [73] -3 hSpCas9 negative selection 10483107
72771842 72771865 13 - 28162770 SKM1 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -0.8663958173804589 [65] [63] -6 hSpCas9 negative selection 10483108
72771820 72771843 13 - 28162770 SKM1 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -2.09209086138975 [40] [16] -8 hSpCas9 negative selection 10483109
72761654 72761677 13 + 28162770 SKM1 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.8423952701935556 [52] [167] 7 hSpCas9 negative selection 10483110
72781709 72781732 13 - 28162770 SKM1 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -3.8220016980220053 [23] [2] -9 hSpCas9 negative selection 10483111
72781699 72781722 13 - 28162770 SKM1 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.7017074643042935 [91] [49] -8 hSpCas9 negative selection 10483112
72773735 72773758 13 - 28162770 SKM1 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 0.34792330342030686 [3] [8] 3 hSpCas9 negative selection 10483113
72772708 72772731 13 - 28162770 SKM1 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.6644604210355256 [51] [57] -5 hSpCas9 negative selection 10483114
72771085 72771108 13 - 28162770 SKM1 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.9970884045800967 [69] [30] -8 hSpCas9 negative selection 10483115
72781624 72781647 13 + 28162770 SKM1 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -5.281433316659303 [175] [7] -9 hSpCas9 negative selection 10652472
72766022 72766045 13 + 28162770 SKM1 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -0.3674358345565242 [53] [73] -3 hSpCas9 negative selection 10652473
72771842 72771865 13 - 28162770 SKM1 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -0.8663958173804589 [65] [63] -6 hSpCas9 negative selection 10652474
72771820 72771843 13 - 28162770 SKM1 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -2.09209086138975 [40] [16] -8 hSpCas9 negative selection 10652475
72761654 72761677 13 + 28162770 SKM1 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.8423952701935556 [52] [167] 7 hSpCas9 negative selection 10652476
72781709 72781732 13 - 28162770 SKM1 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -3.8220016980220053 [23] [2] -9 hSpCas9 negative selection 10652477
72781699 72781722 13 - 28162770 SKM1 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.7017074643042935 [91] [49] -8 hSpCas9 negative selection 10652478
72773735 72773758 13 - 28162770 SKM1 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 0.34792330342030686 [3] [8] 3 hSpCas9 negative selection 10652479
72772708 72772731 13 - 28162770 SKM1 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.6644604210355256 [51] [57] -5 hSpCas9 negative selection 10652480
72771085 72771108 13 - 28162770 SKM1 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.9970884045800967 [69] [30] -8 hSpCas9 negative selection 10652481
72781624 72781647 13 + 28162770 PL21 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -3.638764143443105 [600] [20] -9 hSpCas9 negative selection 10821838
72766022 72766045 13 + 28162770 PL21 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 0.6289829132931944 [103] [69] 5 hSpCas9 negative selection 10821839
72771842 72771865 13 - 28162770 PL21 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.3004306989414633 [248] [21] -8 hSpCas9 negative selection 10821840
72771820 72771843 13 - 28162770 PL21 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -2.4303375454842047 [160] [12] -9 hSpCas9 negative selection 10821841
72761654 72761677 13 + 28162770 PL21 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.0501141704847127 [161] [72] 0 hSpCas9 negative selection 10821842
72781709 72781732 13 - 28162770 PL21 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -5.607215307568284 [111] [0] -9 hSpCas9 negative selection 10821843
72781699 72781722 13 - 28162770 PL21 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -3.6668582539956853 [320] [10] -9 hSpCas9 negative selection 10821844
72773735 72773758 13 - 28162770 PL21 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -0.7998603855106796 [27] [6] -5 hSpCas9 negative selection 10821845
72772708 72772731 13 - 28162770 PL21 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.41243511743969613 [210] [68] -3 hSpCas9 negative selection 10821846
72771085 72771108 13 - 28162770 PL21 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.4306265758449606 [191] [30] -7 hSpCas9 negative selection 10821847
72781624 72781647 13 + 28162770 P31FUJ viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -6.434926028244839 [588] [7] -9 hSpCas9 negative selection 10991204
72766022 72766045 13 + 28162770 P31FUJ viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -1.9594258543591259 [277] [83] -8 hSpCas9 negative selection 10991205
72771842 72771865 13 - 28162770 P31FUJ viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.0615307772645495 [237] [66] -8 hSpCas9 negative selection 10991206
72771820 72771843 13 - 28162770 P31FUJ viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -3.7139288941509947 [133] [11] -9 hSpCas9 negative selection 10991207
72761654 72761677 13 + 28162770 P31FUJ viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.5745527176432255 [199] [349] 6 hSpCas9 negative selection 10991208
72781709 72781732 13 - 28162770 P31FUJ viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -2.5353649744348097 [73] [14] -8 hSpCas9 negative selection 10991209
72781699 72781722 13 - 28162770 P31FUJ viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.5598432226953935 [423] [168] -7 hSpCas9 negative selection 10991210
72773735 72773758 13 - 28162770 P31FUJ viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.5165951704149698 [55] [22] -7 hSpCas9 negative selection 10991211
72772708 72772731 13 - 28162770 P31FUJ viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.7046257297847998 [189] [136] -5 hSpCas9 negative selection 10991212
72771085 72771108 13 - 28162770 P31FUJ viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.1845470358071575 [293] [75] -8 hSpCas9 negative selection 10991213
72781624 72781647 13 + 28162770 OCIAML5 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -7.001813690368679 [283] [3] -9 hSpCas9 negative selection 11160570
72766022 72766045 13 + 28162770 OCIAML5 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -0.5060068135037367 [165] [210] -3 hSpCas9 negative selection 11160571
72771842 72771865 13 - 28162770 OCIAML5 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -1.6864805051460219 [147] [82] -7 hSpCas9 negative selection 11160572
72771820 72771843 13 - 28162770 OCIAML5 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -1.281750846107242 [65] [48] -6 hSpCas9 negative selection 11160573
72761654 72761677 13 + 28162770 OCIAML5 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.9884552151288065 [85] [307] 8 hSpCas9 negative selection 11160574
72781709 72781732 13 - 28162770 OCIAML5 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -6.633426284388657 [54] [0] -9 hSpCas9 negative selection 11160575
72781699 72781722 13 - 28162770 OCIAML5 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -5.629674149527549 [191] [6] -9 hSpCas9 negative selection 11160576
72773735 72773758 13 - 28162770 OCIAML5 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.5890321650302033 [9] [5] -7 hSpCas9 negative selection 11160577
72772708 72772731 13 - 28162770 OCIAML5 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.659421492921601 [69] [79] -4 hSpCas9 negative selection 11160578
72771085 72771108 13 - 28162770 OCIAML5 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.803703549302598 [175] [90] -7 hSpCas9 negative selection 11160579
72781624 72781647 13 + 28162770 EOL1 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -6.3124914257303155 [1055] [6] -9 hSpCas9 negative selection 11329936
72766022 72766045 13 + 28162770 EOL1 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -2.313441504816932 [216] [22] -8 hSpCas9 negative selection 11329937
72771842 72771865 13 - 28162770 EOL1 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.722699007404964 [425] [33] -9 hSpCas9 negative selection 11329938
72771820 72771843 13 - 28162770 EOL1 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -1.5835991320997906 [255] [44] -7 hSpCas9 negative selection 11329939
72761654 72761677 13 + 28162770 EOL1 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.4707407021271154 [351] [256] 4 hSpCas9 negative selection 11329940
72781709 72781732 13 - 28162770 EOL1 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -6.141541418887238 [133] [0] -9 hSpCas9 negative selection 11329941
72781699 72781722 13 - 28162770 EOL1 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -3.4942418625694165 [384] [17] -9 hSpCas9 negative selection 11329942
72773735 72773758 13 - 28162770 EOL1 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -3.1051995718235177 [48] [2] -9 hSpCas9 negative selection 11329943
72772708 72772731 13 - 28162770 EOL1 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -1.0987847322600894 [186] [45] -6 hSpCas9 negative selection 11329944
72771085 72771108 13 - 28162770 EOL1 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -7.189194394478654 [276] [0] -9 hSpCas9 negative selection 11329945
72781624 72781647 13 + 28162770 MOLM13 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -7.954175384628234 [685] [1] -9 hSpCas9 negative selection 11499302
72766022 72766045 13 + 28162770 MOLM13 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -2.3946070947054863 [239] [32] -8 hSpCas9 negative selection 11499303
72771842 72771865 13 - 28162770 MOLM13 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -0.8642344804486721 [354] [140] -5 hSpCas9 negative selection 11499304
72771820 72771843 13 - 28162770 MOLM13 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -3.6613936354003873 [244] [13] -9 hSpCas9 negative selection 11499305
72761654 72761677 13 + 28162770 MOLM13 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 -0.08713583502247355 [309] [210] 0 hSpCas9 negative selection 11499306
72781709 72781732 13 - 28162770 MOLM13 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -1.8857475730701216 [137] [26] -7 hSpCas9 negative selection 11499307
72781699 72781722 13 - 28162770 MOLM13 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -3.0640118754251637 [346] [29] -8 hSpCas9 negative selection 11499308
72773735 72773758 13 - 28162770 MOLM13 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -5.721935177335439 [72] [0] -9 hSpCas9 negative selection 11499309
72772708 72772731 13 - 28162770 MOLM13 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -2.014892724370099 [217] [38] -7 hSpCas9 negative selection 11499310
72771085 72771108 13 - 28162770 MOLM13 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -5.661393635400388 [349] [4] -9 hSpCas9 negative selection 11499311
72781624 72781647 13 + 28162770 HEL viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -5.6177887182228625 [689] [8] -9 hSpCas9 negative selection 11668668
72766022 72766045 13 + 28162770 HEL viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -4.331265959466699 [219] [6] -9 hSpCas9 negative selection 11668669
72771842 72771865 13 - 28162770 HEL viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.0121256819509554 [295] [46] -8 hSpCas9 negative selection 11668670
72771820 72771843 13 - 28162770 HEL viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -6.17104235921668 [224] [1] -9 hSpCas9 negative selection 11668671
72761654 72761677 13 + 28162770 HEL viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 1.0253931574283977 [213] [278] 8 hSpCas9 negative selection 11668672
72781709 72781732 13 - 28162770 HEL viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -2.605188681443229 [94] [9] -8 hSpCas9 negative selection 11668673
72781699 72781722 13 - 28162770 HEL viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -4.463883587533437 [378] [10] -9 hSpCas9 negative selection 11668674
72773735 72773758 13 - 28162770 HEL viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -5.2399042173614845 [58] [0] -9 hSpCas9 negative selection 11668675
72772708 72772731 13 - 28162770 HEL viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.04205893630059393 [171] [106] 0 hSpCas9 negative selection 11668676
72771085 72771108 13 - 28162770 HEL viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -4.758140604281827 [337] [7] -9 hSpCas9 negative selection 11668677
72781624 72781647 13 + 28162770 MV411 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -6.868906410454693 [554] [3] -9 hSpCas9 negative selection 11838034
72766022 72766045 13 + 28162770 MV411 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 0.3410966579970206 [163] [174] 3 hSpCas9 negative selection 11838035
72771842 72771865 13 - 28162770 MV411 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -1.7744772256456653 [198] [48] -8 hSpCas9 negative selection 11838036
72771820 72771843 13 - 28162770 MV411 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -1.1740262176555016 [149] [55] -6 hSpCas9 negative selection 11838037
72761654 72761677 13 + 28162770 MV411 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.28540540098179584 [149] [153] 2 hSpCas9 negative selection 11838038
72781709 72781732 13 - 28162770 MV411 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -4.909066934897216 [106] [2] -9 hSpCas9 negative selection 11838039
72781699 72781722 13 - 28162770 MV411 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -3.229971808783577 [322] [28] -9 hSpCas9 negative selection 11838040
72773735 72773758 13 - 28162770 MV411 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -2.6785618677734475 [37] [4] -9 hSpCas9 negative selection 11838041
72772708 72772731 13 - 28162770 MV411 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.5540167698351445 [121] [69] -4 hSpCas9 negative selection 11838042
72771085 72771108 13 - 28162770 MV411 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.1358910887687306 [239] [45] -8 hSpCas9 negative selection 11838043
72781624 72781647 13 + 28162770 MONOMAC1 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -3.296025941690921 [376] [43] -9 hSpCas9 negative selection 12007400
72766022 72766045 13 + 28162770 MONOMAC1 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -0.23968118446804731 [102] [99] -2 hSpCas9 negative selection 12007401
72771842 72771865 13 - 28162770 MONOMAC1 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -1.5449601504798605 [139] [54] -8 hSpCas9 negative selection 12007402
72771820 72771843 13 - 28162770 MONOMAC1 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -3.184097791352056 [110] [13] -9 hSpCas9 negative selection 12007403
72761654 72761677 13 + 28162770 MONOMAC1 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.338172618464503 [117] [170] 3 hSpCas9 negative selection 12007404
72781709 72781732 13 - 28162770 MONOMAC1 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -5.32631986400452 [34] [0] -9 hSpCas9 negative selection 12007405
72781699 72781722 13 - 28162770 MONOMAC1 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.5380737648946208 [151] [59] -8 hSpCas9 negative selection 12007406
72773735 72773758 13 - 28162770 MONOMAC1 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.9696263509564813 [40] [11] -8 hSpCas9 negative selection 12007407
72772708 72772731 13 - 28162770 MONOMAC1 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -2.3728866824589714 [121] [26] -9 hSpCas9 negative selection 12007408
72771085 72771108 13 - 28162770 MONOMAC1 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -1.921929608925185 [118] [35] -8 hSpCas9 negative selection 12007409
72781624 72781647 13 + 28162770 OCIAML2 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -4.875020080321496 [89] [16] -9 hSpCas9 negative selection 12176766
72766022 72766045 13 + 28162770 OCIAML2 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 -1.2075954194083673 [34] [83] -7 hSpCas9 negative selection 12176767
72771842 72771865 13 - 28162770 OCIAML2 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -2.3450989431583023 [43] [47] -8 hSpCas9 negative selection 12176768
72771820 72771843 13 - 28162770 OCIAML2 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -1.590924058959873 [24] [45] -7 hSpCas9 negative selection 12176769
72761654 72761677 13 + 28162770 OCIAML2 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 -0.06750564750681787 [37] [200] 0 hSpCas9 negative selection 12176770
72781709 72781732 13 - 28162770 OCIAML2 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -6.862947248020921 [20] [0] -9 hSpCas9 negative selection 12176771
72781699 72781722 13 - 28162770 OCIAML2 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.9532306083336395 [50] [72] -8 hSpCas9 negative selection 12176772
72773735 72773758 13 - 28162770 OCIAML2 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -1.4706298252421615 [2] [5] -7 hSpCas9 negative selection 12176773
72772708 72772731 13 - 28162770 OCIAML2 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -1.2200863635915644 [28] [68] -7 hSpCas9 negative selection 12176774
72771085 72771108 13 - 28162770 OCIAML2 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -2.02317084827094 [32] [44] -8 hSpCas9 negative selection 12176775
72781624 72781647 13 + 28162770 OCIAML3 viability GTGTCGGGCAGCAAGTAGTGCGG DIS3 ENSG00000083520 -3.017607153106431 [168] [62] -9 hSpCas9 negative selection 12346132
72766022 72766045 13 + 28162770 OCIAML3 viability GTGGAATCGAACTTCAGGAGAGG DIS3 ENSG00000083520 0.048670358253280435 [48] [152] 0 hSpCas9 negative selection 12346133
72771842 72771865 13 - 28162770 OCIAML3 viability TATTAGGCCAGGAAATGCCTTGG DIS3 ENSG00000083520 -0.8794098591864113 [77] [127] -6 hSpCas9 negative selection 12346134
72771820 72771843 13 - 28162770 OCIAML3 viability GATCAAGAATCAGCCAGAAGAGG DIS3 ENSG00000083520 -0.9945455699078918 [32] [49] -6 hSpCas9 negative selection 12346135
72761654 72761677 13 + 28162770 OCIAML3 viability GAAAAGCCACTGATGCACGTTGG DIS3 ENSG00000083520 0.6763901539231172 [56] [274] 6 hSpCas9 negative selection 12346136
72781709 72781732 13 - 28162770 OCIAML3 viability CGGGTGCGCAGCGTGTGGAGGGG DIS3 ENSG00000083520 -6.72329065726913 [34] [0] -9 hSpCas9 negative selection 12346137
72781699 72781722 13 - 28162770 OCIAML3 viability GCGTGTGGAGGGGCGCACGAGGG DIS3 ENSG00000083520 -1.9197778015059197 [93] [74] -8 hSpCas9 negative selection 12346138
72773735 72773758 13 - 28162770 OCIAML3 viability AGGCTTCCACATTAGAAGGACGG DIS3 ENSG00000083520 -2.4013625623817676 [13] [7] -9 hSpCas9 negative selection 12346139
72772708 72772731 13 - 28162770 OCIAML3 viability GTTTTCTGCCAAAGATGCCCTGG DIS3 ENSG00000083520 -0.09831247770009437 [49] [140] -1 hSpCas9 negative selection 12346140
72771085 72771108 13 - 28162770 OCIAML3 viability GTGTTCCTTAAAATGTGACGTGG DIS3 ENSG00000083520 -3.389187848435665 [58] [16] -9 hSpCas9 negative selection 12346141