Gene2Function

Crispr

Gene Info

Species: Human (Homo sapiens)
GeneID: 29980
Symbol: DONSON
Description: DNA replication fork stabilization factor DONSON

DataSource: http://genomecrispr.dkfz.de/#!/results/DONSON

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
33582174	33582197	21	-	26472758	Jiyoye	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-2.2793251456773453	[102]	[15]	-8	hSpCas9	negative selection	46044
33581333	33581356	21	+	26472758	Jiyoye	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-6.690856701454654	[136]	[0]	-9	hSpCas9	negative selection	46045
33582174	33582197	21	-	26472758	KBM7	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.1492356161333288	[886,931]	[170,214]	-7	hSpCas9	negative selection	237162
33581333	33581356	21	+	26472758	KBM7	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-1.8798322182837832	[369,396]	[69,30]	-8	hSpCas9	negative selection	237163
33582174	33582197	21	-	26472758	Raji	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-2.542870425599276	[451]	[17]	-9	hSpCas9	negative selection	428280
33581333	33581356	21	+	26472758	Raji	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.441053089322443	[233]	[4]	-9	hSpCas9	negative selection	428281
33582174	33582197	21	-	26472758	K562	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.0268161592692076	[740]	[306]	-5	hSpCas9	negative selection	619398
33581333	33581356	21	+	26472758	K562	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-5.247434368663228	[359]	[7]	-9	hSpCas9	negative selection	619399
33583560	33583583	21	+	26627737	DLD1	viability	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.7989966613422337	[1468]	[30,75,87]	-9	hSpCas9	negative selection	816065
33583560	33583583	21	+	26627737	GBM cells	viability after 5 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.2438031680363872	[498]	[45,66]	-9	hSpCas9	negative selection	898380
33583560	33583583	21	+	26627737	GBM cells	viability after 13 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.850843109244283	[498]	[31,7]	-9	hSpCas9	negative selection	980695
33583560	33583583	21	+	26627737	GBM cells	viability after 21 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-5.00655972663581	[498]	[9,6]	-9	hSpCas9	negative selection	1063010
33583560	33583583	21	+	26627737	RPE1	viability after 9 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.6031592696603605	[1380]	[42,25]	-9	hSpCas9	negative selection	1145325
33583560	33583583	21	+	26627737	RPE1	viability after 12 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-5.870253343179773	[1380]	[0,11]	-9	hSpCas9	negative selection	1227640
33583560	33583583	21	+	26627737	RPE1	viability after 15 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.6724980858645955	[1380]	[50,10]	-9	hSpCas9	negative selection	1309955
33583560	33583583	21	+	26627737	RPE1	viability after 18 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-5.650981591044513	[1380]	[4,9]	-9	hSpCas9	negative selection	1392270
33583560	33583583	21	+	26627737	HeLa	viability after 8 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.7509724289175908	[1110]	[48,112,49]	-9	hSpCas9	negative selection	1474585
33583560	33583583	21	+	26627737	HeLa	viability after 12 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.045597902706594	[1110]	[125,92,116]	-9	hSpCas9	negative selection	1556900
33583560	33583583	21	+	26627737	HeLa	viability after 15 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.831363487293472	[1110]	[134,23,27]	-9	hSpCas9	negative selection	1639215
33583560	33583583	21	+	26627737	HeLa	viability after 18 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.9823025269515426	[1110]	[78,18,27]	-9	hSpCas9	negative selection	1721530
33583560	33583583	21	+	26627737	HCT116	viability after 6 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-1.280566729273879	[774]	[73,36]	-6	hSpCas9	negative selection	1803845
33583560	33583583	21	+	26627737	HCT116	viability after 8 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.5222443609347414	[739]	[81,48,81]	-9	hSpCas9	negative selection	1886160
33583560	33583583	21	+	26627737	HCT116	viability after 9 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-1.6879945495382227	[774]	[42,80]	-8	hSpCas9	negative selection	1968475
33583560	33583583	21	+	26627737	HCT116	viability after 12 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.633263043519239	[739]	[35,87,66]	-9	hSpCas9	negative selection	2050790
33583560	33583583	21	+	26627737	HCT116	viability after 15 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.2378322164193825	[739]	[22,108,0]	-9	hSpCas9	negative selection	2133105
33583560	33583583	21	+	26627737	HCT116	viability after 18 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-4.120847418936798	[739]	[28,22,8]	-9	hSpCas9	negative selection	2215420
33580787	33580810	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAGAATCGCTTGAACCCCAG	DONSON	ENSG00000159147	0.6947743245442068	[118,16]	[8,38]	3	dCas9-VP64	positive selection	2469020
33580787	33580810	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAGAATCGCTTGAACCCCAG	DONSON	ENSG00000159147	-1.217410828372933	[137,230]	[25,24]	-9	dCas9-VP64	positive selection	2564275
33584656	33584679	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.486914046518125	[200,227]	[0,0]	-3	hSpCas9	positive selection	3346800
33584657	33584680	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTATCAGCTCCAATACGAGGG	DONSON	ENSG00000159147	-16.7064837465363	[]	[]	-9	hSpCas9	negative selection	3500968
33584657	33584680	21	+	26780180	A375	viability (Avana lentiGuide)	TTCTATCAGCTCCAATACGAGGG	DONSON	ENSG00000159147	22.0168055809897	[]	[]	9	hSpCas9	negative selection	3609627
33584657	33584680	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTATCAGCTCCAATACGAGGG	DONSON	ENSG00000159147	-0.7322681501545345	[7]	[4,3]	-8	hSpCas9	positive selection	3718286
33584657	33584680	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTATCAGCTCCAATACGAGGG	DONSON	ENSG00000159147	-1.4115777445280884	[6]	[2,0]	-9	hSpCas9	positive selection	3826893
33584656	33584679	21	+	26780180	A375	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	1.80888945041556	[]	[]	9	hSpCas9	negative selection	3934308
33584656	33584679	21	+	26780180	HT29	viability (GeCKOv2 library)	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	1.28915047595396	[]	[]	6	hSpCas9	negative selection	4042274
33569074	33569097	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGTGTACCTTTTTAATCCAGG	DONSON	ENSG00000159147	0.2919565993262168	[3]	[2,3]	7	hSpCas9	positive selection	4172767
33569066	33569089	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.22350696892843758	[2]	[0,1]	-5	hSpCas9	positive selection	4172772
33569074	33569097	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGTGTACCTTTTTAATCCAGG	DONSON	ENSG00000159147	0.8489051402900234	[3]	[4,2,1,2]	5	hSpCas9	positive selection	4236789
33569066	33569089	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	1.0459755672796738	[3]	[3,2,3,3]	7	hSpCas9	positive selection	4236794
33584656	33584679	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	0.09343976369743562	[4]	[4,3]	2	hSpCas9	positive selection	4267488
33575864	33575887	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.2138062309877518	[2]	[2,0]	-4	hSpCas9	positive selection	4299802
33569066	33569089	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.4140759651178591	[3]	[4,3]	8	hSpCas9	positive selection	4364053
33583597	33583619	21	+	27760321	OCIAML3	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-0.3399904863591878	[16,18]	[5,17]	-4	hSpCas9	negative selection	4395628
33583597	33583619	21	+	27760321	OCIAML2	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-3.8753432803668186	[16,18]	[0,0]	-9	hSpCas9	negative selection	4479091
33583597	33583619	21	+	27760321	MV411	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-3.581519346187088	[16,18]	[0,0]	-9	hSpCas9	negative selection	4562554
33583597	33583619	21	+	27760321	HL60	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-3.8893895079812246	[16,18]	[0,0]	-9	hSpCas9	negative selection	4646017
33583597	33583619	21	+	27760321	HT1080	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-2.7606711187674797	[18,14]	[0,0]	-7	hSpCas9	negative selection	4729480
33583597	33583619	21	+	27760321	HT29	viability after 7 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.450331372316744	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	4812943
33583597	33583619	21	+	27760321	HT29	viability after 25 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.2803533836140035	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	4896406
33583597	33583619	21	+	27760321	HT29	viability after 22 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.297672015473263	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	4979869
33583597	33583619	21	+	27760321	HT29	viability after 19 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.28183196305005	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	5063332
33583597	33583619	21	+	27760321	HT29	viability after 16 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.250367510629128	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	5146795
33583597	33583619	21	+	27760321	HT29	viability after 13 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.302654910073266	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	5230258
33583597	33583619	21	+	27760321	HT29	viability after 10 days	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-4.40866621723361	[18,14]	[0,0,0]	-9	hSpCas9	negative selection	5313721
33583597	33583619	21	+	27760321	MOLM13	viability	GGTACAAACGTAGAAATAGGGG	DONSON	ENSG00000159147	-3.3554625333594927	[16,18]	[0,0]	-9	hSpCas9	negative selection	5397184
33584656	33584679	21	+	27260156	BXPC3	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.578173266886875	[1242]	[756,912,757,1081]	-8	hSpCas9	negative selection	5539948
33575864	33575887	21	-	27260156	BXPC3	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.08327593400139965	[277]	[263,264,273,296]	-2	hSpCas9	negative selection	5572262
33569066	33569089	21	+	27260156	BXPC3	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.01095125703522526	[842]	[900,820,969,853]	0	hSpCas9	negative selection	5636513
33584656	33584679	21	+	27260156	A673	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.11213357163125592	[1242]	[1460,1261,1351,1462]	-3	hSpCas9	negative selection	5661199
33575864	33575887	21	-	27260156	A673	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.060855333929074384	[277]	[346,306,293,335]	-1	hSpCas9	negative selection	5693513
33569066	33569089	21	+	27260156	A673	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.027360021027509673	[842]	[1169,989,834,997]	0	hSpCas9	negative selection	5757764
33584656	33584679	21	+	27260156	A375	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.5155103966769007	[1242]	[1413,1168,837,699]	-6	hSpCas9	negative selection	5782450
33575864	33575887	21	-	27260156	A375	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.18477177848003878	[277]	[288,378,204,281]	-3	hSpCas9	negative selection	5814764
33569066	33569089	21	+	27260156	A375	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.04812675248758591	[842]	[887,1375,1075,802]	0	hSpCas9	negative selection	5879015
33584656	33584679	21	+	27260156	COLO741	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	0.03541241498068026	[1242]	[1999,1489,1434]	0	hSpCas9	negative selection	5903701
33575864	33575887	21	-	27260156	COLO741	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.16560776260559706	[277]	[246,357,336]	-4	hSpCas9	negative selection	5936015
33569066	33569089	21	+	27260156	COLO741	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.04220977295432604	[842]	[1090,1050,1000]	-1	hSpCas9	negative selection	6000266
33584656	33584679	21	+	27260156	CAL120	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.09249681662452836	[1242]	[1526,1439,1396]	-1	hSpCas9	negative selection	6024952
33575864	33575887	21	-	27260156	CAL120	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.04713396881042431	[277]	[305,359,333]	0	hSpCas9	negative selection	6057266
33569066	33569089	21	+	27260156	CAL120	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.3027283707792998	[842]	[1315,1464,1106]	4	hSpCas9	negative selection	6121517
33584656	33584679	21	+	27260156	CADOES1	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.16637434790542338	[1242]	[939,931,1257,988]	-3	hSpCas9	negative selection	6146203
33575864	33575887	21	-	27260156	CADOES1	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.03334253167447043	[277]	[196,126,342,346]	0	hSpCas9	negative selection	6178517
33569066	33569089	21	+	27260156	CADOES1	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.41636452934324186	[842]	[1032,1137,856,1161]	7	hSpCas9	negative selection	6242768
33584656	33584679	21	+	27260156	EWS502	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.29906108127227915	[1242]	[1228,1007,913,1108]	-5	hSpCas9	negative selection	6267454
33575864	33575887	21	-	27260156	EWS502	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.10379899598689946	[277]	[315,319,219,413]	1	hSpCas9	negative selection	6299768
33569066	33569089	21	+	27260156	EWS502	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.38139119907726204	[842]	[839,1341,1177,1331]	6	hSpCas9	negative selection	6364019
33584656	33584679	21	+	27260156	EW8	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.2416239350972993	[1242]	[1005,926,662,858]	-4	hSpCas9	negative selection	6388705
33575864	33575887	21	-	27260156	EW8	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.04541521454563402	[277]	[266,239,147,234]	-1	hSpCas9	negative selection	6421019
33569066	33569089	21	+	27260156	EW8	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.3101912343018285	[842]	[930,859,854,747]	5	hSpCas9	negative selection	6485270
33584656	33584679	21	+	27260156	CORL105	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.27951624112793416	[1242]	[1272,980,1384,1191]	-5	hSpCas9	negative selection	6509956
33575864	33575887	21	-	27260156	CORL105	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.3116793375958651	[277]	[255,226,342,235]	-5	hSpCas9	negative selection	6542270
33569066	33569089	21	+	27260156	CORL105	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.313752100760479	[842]	[792,657,1007,752]	-5	hSpCas9	negative selection	6606521
33584656	33584679	21	+	27260156	HS294T	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	0.017930543003515487	[1242]	[319,432,402,870]	0	hSpCas9	negative selection	6631207
33575864	33575887	21	-	27260156	HS294T	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.18469897954428816	[277]	[115,68,75,119]	-3	hSpCas9	negative selection	6663521
33569066	33569089	21	+	27260156	HS294T	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.1386045841292456	[842]	[252,195,350,409]	-2	hSpCas9	negative selection	6727772
33584656	33584679	21	+	27260156	HCC44	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.43517160663940424	[1242]	[917,918,1346,1025]	-6	hSpCas9	negative selection	6752458
33575864	33575887	21	-	27260156	HCC44	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.08064863603290229	[277]	[187,159,531,354]	-1	hSpCas9	negative selection	6784772
33569066	33569089	21	+	27260156	HCC44	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.4060089483199565	[842]	[1519,1452,1267,813]	6	hSpCas9	negative selection	6849023
33584656	33584679	21	+	27260156	G402	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.07865446840315737	[1242]	[1462,1676,1006,1601]	-1	hSpCas9	negative selection	6873709
33575864	33575887	21	-	27260156	G402	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.3399550105164845	[277]	[446,286,609,368]	4	hSpCas9	negative selection	6906023
33569066	33569089	21	+	27260156	G402	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.653858209584177	[842]	[1614,1742,1134,1963]	7	hSpCas9	negative selection	6970274
33584656	33584679	21	+	27260156	L33	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.23788051552007783	[1242]	[1028,468,558,1151]	-5	hSpCas9	negative selection	6994960
33575864	33575887	21	-	27260156	L33	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.3892680242449058	[277]	[233,118,101,161]	-7	hSpCas9	negative selection	7027274
33569066	33569089	21	+	27260156	L33	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.2753960258467365	[842]	[944,391,605,1214]	6	hSpCas9	negative selection	7091525
33584656	33584679	21	+	27260156	K562	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.5107963348281821	[1242]	[846,1083,630,576]	-6	hSpCas9	negative selection	7116211
33575864	33575887	21	-	27260156	K562	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.3226348596980747	[277]	[194,490,397,165]	4	hSpCas9	negative selection	7148525
33569066	33569089	21	+	27260156	K562	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.13239350468028332	[842]	[788,1176,782,572]	1	hSpCas9	negative selection	7212776
33584656	33584679	21	+	27260156	HT29	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.7909394018101993	[1242]	[1126,819,817,751]	-8	hSpCas9	negative selection	7237462
33575864	33575887	21	-	27260156	HT29	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.14644552046167958	[277]	[520,315,223,189]	-3	hSpCas9	negative selection	7269776
33569066	33569089	21	+	27260156	HT29	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.10374732212796378	[842]	[916,1264,1000,1200]	2	hSpCas9	negative selection	7334027
33584656	33584679	21	+	27260156	MHHES1	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.3174058975331979	[1242]	[1311,1016,1223,964]	-5	hSpCas9	negative selection	7358713
33575864	33575887	21	-	27260156	MHHES1	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.053200635510627925	[277]	[294,479,269,196]	-1	hSpCas9	negative selection	7391027
33569066	33569089	21	+	27260156	MHHES1	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.017522028267096146	[842]	[955,1158,952,734]	0	hSpCas9	negative selection	7455278
33584656	33584679	21	+	27260156	MEWO	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.024290125303059185	[1242]	[1452,973,1063]	0	hSpCas9	negative selection	7479964
33575864	33575887	21	-	27260156	MEWO	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.10427505110047541	[277]	[247,235,242]	-2	hSpCas9	negative selection	7512278
33569066	33569089	21	+	27260156	MEWO	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.03727623560952242	[842]	[928,685,721]	-1	hSpCas9	negative selection	7576529
33584656	33584679	21	+	27260156	LNCAPCLONEFGC	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.271208463251815	[1242]	[997,763,1105,898]	-4	hSpCas9	negative selection	7601215
33575864	33575887	21	-	27260156	LNCAPCLONEFGC	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.06993822578256847	[277]	[208,284,217,337]	1	hSpCas9	negative selection	7633529
33569066	33569089	21	+	27260156	LNCAPCLONEFGC	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.2979204031202254	[842]	[973,843,964,980]	5	hSpCas9	negative selection	7697780
33584656	33584679	21	+	27260156	PANC0327	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.3141155341425821	[1242]	[1667,758,782,422]	-4	hSpCas9	negative selection	7722466
33575864	33575887	21	-	27260156	PANC0327	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.13005133255352908	[277]	[205,197,327,352]	2	hSpCas9	negative selection	7754780
33569066	33569089	21	+	27260156	PANC0327	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.1350510502643164	[842]	[928,764,721,888]	2	hSpCas9	negative selection	7819031
33584656	33584679	21	+	27260156	NCIH2009	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.8911543657909874	[1242]	[1140,880,826]	-8	hSpCas9	negative selection	7843717
33575864	33575887	21	-	27260156	NCIH2009	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.042203822299075266	[277]	[424,349,429]	0	hSpCas9	negative selection	7876031
33569066	33569089	21	+	27260156	NCIH2009	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.08354944344501303	[842]	[1545,1184,1070]	1	hSpCas9	negative selection	7940282
33584656	33584679	21	+	27260156	NCIH1373	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.5174042838255898	[1242]	[1172,906,828,268]	-5	hSpCas9	negative selection	7964968
33575864	33575887	21	-	27260156	NCIH1373	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.6167013886085286	[277]	[379,370,470,182]	6	hSpCas9	negative selection	7997282
33569066	33569089	21	+	27260156	NCIH1373	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.1488254094014323	[842]	[1206,1021,1134,218]	1	hSpCas9	negative selection	8061533
33584656	33584679	21	+	27260156	PATU8902	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.3148368958541494	[1242]	[1395,1375,919,2066]	-3	hSpCas9	negative selection	8086219
33575864	33575887	21	-	27260156	PATU8902	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.3224913658205305	[277]	[1050,418,159,364]	3	hSpCas9	negative selection	8118533
33569066	33569089	21	+	27260156	PATU8902	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.0019183923364824995	[842]	[905,1344,883,1685]	0	hSpCas9	negative selection	8182784
33584656	33584679	21	+	27260156	PANC1	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.6230741861088929	[1242]	[807,751,567,648]	-7	hSpCas9	negative selection	8207470
33575864	33575887	21	-	27260156	PANC1	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.14551254027707816	[277]	[225,275,371,193]	2	hSpCas9	negative selection	8239784
33569066	33569089	21	+	27260156	PANC1	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.31781488851090334	[842]	[601,437,566,662]	-5	hSpCas9	negative selection	8304035
33584656	33584679	21	+	27260156	PANC0813	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.7510226420267905	[1242]	[808,890,801,955]	-8	hSpCas9	negative selection	8328721
33575864	33575887	21	-	27260156	PANC0813	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.14823782257975204	[277]	[368,274,317,226]	-2	hSpCas9	negative selection	8361035
33569066	33569089	21	+	27260156	PANC0813	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.009596543615679631	[842]	[1078,1042,982,893]	0	hSpCas9	negative selection	8425286
33584656	33584679	21	+	27260156	RDES	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.14616937338943026	[1242]	[987,1158,1338,1801]	-2	hSpCas9	negative selection	8449972
33575864	33575887	21	-	27260156	RDES	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.05671692952952667	[277]	[302,302,302,433]	0	hSpCas9	negative selection	8482286
33569066	33569089	21	+	27260156	RDES	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.28698961161562986	[842]	[717,1097,1390,1687]	4	hSpCas9	negative selection	8546537
33584656	33584679	21	+	27260156	PC3	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.09433774837552145	[1242]	[742,1167,1788,1257]	-2	hSpCas9	negative selection	8571223
33575864	33575887	21	-	27260156	PC3	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.33514989407122053	[277]	[173,336,784,320]	7	hSpCas9	negative selection	8603537
33569066	33569089	21	+	27260156	PC3	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.22179902266151386	[842]	[557,1152,1558,959]	5	hSpCas9	negative selection	8667788
33584656	33584679	21	+	27260156	PATU8988T	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.3568373211233773	[1242]	[1377,645,838,855]	-5	hSpCas9	negative selection	8692474
33575864	33575887	21	-	27260156	PATU8988T	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.2080876914970754	[277]	[371,221,246,399]	3	hSpCas9	negative selection	8724788
33569066	33569089	21	+	27260156	PATU8988T	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.20761275011520497	[842]	[804,970,908,1092]	3	hSpCas9	negative selection	8789039
33584656	33584679	21	+	27260156	T47D	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.07915502722919987	[1242]	[1383,1265,1331,1514]	-2	hSpCas9	negative selection	8813725
33575864	33575887	21	-	27260156	T47D	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.1695956157581735	[277]	[358,299,424,377]	3	hSpCas9	negative selection	8846039
33569066	33569089	21	+	27260156	T47D	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.2558453800788365	[842]	[1107,1140,1210,1233]	5	hSpCas9	negative selection	8910290
33584656	33584679	21	+	27260156	SU8686	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.8761053535305973	[1242]	[612,574,756,773]	-8	hSpCas9	negative selection	8934976
33575864	33575887	21	-	27260156	SU8686	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.21700663267327502	[277]	[243,214,316,162]	-4	hSpCas9	negative selection	8967290
33569066	33569089	21	+	27260156	SU8686	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.4110285944688892	[842]	[937,1216,1144,1149]	7	hSpCas9	negative selection	9031541
33584656	33584679	21	+	27260156	SKES1	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.18498725066699406	[1242]	[949,1442,1061,937]	-4	hSpCas9	negative selection	9056227
33575864	33575887	21	-	27260156	SKES1	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.008794718412854508	[277]	[397,237,169,303]	0	hSpCas9	negative selection	9088541
33569066	33569089	21	+	27260156	SKES1	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	-0.0022020605036804364	[842]	[700,976,901,773]	0	hSpCas9	negative selection	9152792
33584656	33584679	21	+	27260156	TOV112D	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	-0.3223224654222343	[1242]	[954,1184,953,931]	-6	hSpCas9	negative selection	9177478
33575864	33575887	21	-	27260156	TOV112D	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.09246312925081157	[277]	[221,386,266,325]	1	hSpCas9	negative selection	9209792
33569066	33569089	21	+	27260156	TOV112D	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.4328167742195672	[842]	[1158,1900,984,712]	7	hSpCas9	negative selection	9274043
33584656	33584679	21	+	27260156	TC71	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	0.09931155367791189	[1242]	[1394,1461,1287,1578]	2	hSpCas9	negative selection	9298729
33575864	33575887	21	-	27260156	TC71	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	-0.06398221402671811	[277]	[361,213,205,363]	-2	hSpCas9	negative selection	9331043
33569066	33569089	21	+	27260156	TC71	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.31626722788859096	[842]	[987,995,1245,1278]	7	hSpCas9	negative selection	9395294
33584656	33584679	21	+	27260156	TC32	viability	TTTCTATCAGCTCCAATACGAGG	DONSON	ENSG00000159147	0.16911364860693534	[1242]	[1372,994,1706,1276]	3	hSpCas9	negative selection	9419980
33575864	33575887	21	-	27260156	TC32	viability	AGAAAATGTTTGCGATGATCAGG	DONSON	ENSG00000159147	0.2830018473136551	[277]	[287,232,385,397]	5	hSpCas9	negative selection	9452294
33569066	33569089	21	+	27260156	TC32	viability	TGCCCAAGCCTGGATTAAAAAGG	DONSON	ENSG00000159147	0.20032677460503212	[842]	[891,775,1059,935]	3	hSpCas9	negative selection	9516545
33583560	33583583	21	+	27869803	HPAFII	viability after 27 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.5318511642615937	[451]	[31,10,NaN]	-9	hSpCas9	negative selection	9579125
33583560	33583583	21	+	27869803	HPAFII	viability after 15 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-2.144926942615904	[451]	[152,82,NaN]	-9	hSpCas9	negative selection	9661574
33583560	33583583	21	+	27869803	ASPC1	viability after 36 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-1.280727374394112	[1277]	[217,206,138]	-8	hSpCas9	negative selection	9744023
33583560	33583583	21	+	27869803	PATU8988S	viability after 35 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.163379782137499	[1167]	[54,49,NaN]	-9	hSpCas9	negative selection	9826472
33583560	33583583	21	+	27869803	PATU8988S	viability after 31 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.426631663382541	[1167]	[8,86,NaN]	-9	hSpCas9	negative selection	9908921
33583560	33583583	21	+	27869803	HPAFII	viability after 35 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.9025933918205116	[451]	[27,0,NaN]	-9	hSpCas9	negative selection	9991370
33583560	33583583	21	+	27869803	HPAFII	viability after 31 days	CTAATCCTGCTGCTCGGAACAGG	DONSON	ENSG00000159147	-3.9952049368971068	[451]	[24,5,NaN]	-9	hSpCas9	negative selection	10073819
33582174	33582197	21	-	28162770	P31FUJ	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.4363355984995105	[379]	[164]	-7	hSpCas9	negative selection	10145987
33581333	33581356	21	+	28162770	P31FUJ	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.6590669591164766	[214]	[19]	-9	hSpCas9	negative selection	10145988
33582174	33582197	21	-	28162770	TF1	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10315353
33581333	33581356	21	+	28162770	TF1	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10315354
33582174	33582197	21	-	28162770	SKM1	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-0.2840366768380188	[103]	[150]	-2	hSpCas9	negative selection	10484719
33581333	33581356	21	+	28162770	SKM1	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.2066655482573307	[46]	[8]	-9	hSpCas9	negative selection	10484720
33582174	33582197	21	-	28162770	SKM1	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-0.2840366768380188	[103]	[150]	-2	hSpCas9	negative selection	10654085
33581333	33581356	21	+	28162770	SKM1	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.2066655482573307	[46]	[8]	-9	hSpCas9	negative selection	10654086
33582174	33582197	21	-	28162770	PL21	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.5731678267406064	[334]	[48]	-7	hSpCas9	negative selection	10823451
33581333	33581356	21	+	28162770	PL21	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-2.2035825715616895	[126]	[11]	-8	hSpCas9	negative selection	10823452
33582174	33582197	21	-	28162770	P31FUJ	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.4363355984995105	[379]	[164]	-7	hSpCas9	negative selection	10992817
33581333	33581356	21	+	28162770	P31FUJ	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.6590669591164766	[214]	[19]	-9	hSpCas9	negative selection	10992818
33582174	33582197	21	-	28162770	OCIAML5	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-0.5785014975380337	[181]	[219]	-4	hSpCas9	negative selection	11162183
33581333	33581356	21	+	28162770	OCIAML5	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.0484637836675006	[109]	[23]	-8	hSpCas9	negative selection	11162184
33582174	33582197	21	-	28162770	EOL1	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-2.0957246234557267	[429]	[52]	-8	hSpCas9	negative selection	11331549
33581333	33581356	21	+	28162770	EOL1	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-0.4216278695635052	[149]	[58]	-3	hSpCas9	negative selection	11331550
33582174	33582197	21	-	28162770	MOLM13	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-2.2311796048630987	[525]	[80]	-7	hSpCas9	negative selection	11500915
33581333	33581356	21	+	28162770	MOLM13	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-5.326526484805528	[221]	[3]	-9	hSpCas9	negative selection	11500916
33582174	33582197	21	-	28162770	HEL	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.1666552353308457	[353]	[100]	-6	hSpCas9	negative selection	11670281
33581333	33581356	21	+	28162770	HEL	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-5.190151182164385	[170]	[2]	-9	hSpCas9	negative selection	11670282
33582174	33582197	21	-	28162770	MV411	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.7964652710940396	[366]	[88]	-8	hSpCas9	negative selection	11839647
33581333	33581356	21	+	28162770	MV411	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-4.466807966883347	[104]	[3]	-9	hSpCas9	negative selection	11839648
33582174	33582197	21	-	28162770	MONOMAC1	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-2.0595333233096187	[199]	[54]	-9	hSpCas9	negative selection	12009013
33581333	33581356	21	+	28162770	MONOMAC1	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-2.1085001724578967	[78]	[20]	-9	hSpCas9	negative selection	12009014
33582174	33582197	21	-	28162770	OCIAML2	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.4105088328045903	[46]	[97]	-7	hSpCas9	negative selection	12178379
33581333	33581356	21	+	28162770	OCIAML2	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.1811232080471763	[35]	[21]	-9	hSpCas9	negative selection	12178380
33582174	33582197	21	-	28162770	OCIAML3	viability	ACAGCATCTGGAACAAGCTTGGG	DONSON	ENSG00000159147	-1.1789701410453195	[80]	[107]	-7	hSpCas9	negative selection	12347745
33581333	33581356	21	+	28162770	OCIAML3	viability	GCAACAGGGGACAAGAGGGTTGG	DONSON	ENSG00000159147	-3.382503535130451	[75]	[21]	-9	hSpCas9	negative selection	12347746