Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1859
• Symbol: DYRK1A
• Description: dual specificity tyrosine phosphorylation regulated kinase 1A

DataSource: http://genomecrispr.dkfz.de/#!/results/DYRK1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
37472728	37472751	21	-	26472758	Jiyoye	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	47618
37493102	37493125	21	-	26472758	Jiyoye	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.057665673693584274	[166]	[120]	0	hSpCas9	negative selection	47619
37490257	37490280	21	+	26472758	Jiyoye	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	1.4322663624687038	[56]	[115]	8	hSpCas9	negative selection	47620
37493140	37493163	21	-	26472758	Jiyoye	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-0.20988074892513597	[249]	[162]	-1	hSpCas9	negative selection	47621
37505328	37505351	21	+	26472758	Jiyoye	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.4859094145776144	[103]	[27]	-7	hSpCas9	negative selection	47622
37472707	37472730	21	-	26472758	Jiyoye	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.18200051949809848	[345]	[295]	1	hSpCas9	negative selection	47623
37472754	37472777	21	-	26472758	Jiyoye	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-1.026920453588655	[126]	[46]	-6	hSpCas9	negative selection	47624
37480653	37480676	21	+	26472758	Jiyoye	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.6639856474153656	[186]	[88]	-5	hSpCas9	negative selection	47625
37496160	37496183	21	-	26472758	Jiyoye	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.10761509964696558	[47]	[38]	0	hSpCas9	negative selection	47626
37505566	37505589	21	-	26472758	Jiyoye	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.14963607890113373	[202]	[137]	-1	hSpCas9	negative selection	47627
37472728	37472751	21	-	26472758	KBM7	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.0001208687159862	[69,32]	[16,6]	-6	hSpCas9	negative selection	238736
37493102	37493125	21	-	26472758	KBM7	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.01465042631401714	[676,684]	[399,245]	0	hSpCas9	negative selection	238737
37490257	37490280	21	+	26472758	KBM7	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.4897586939970924	[477,311]	[109,147]	-4	hSpCas9	negative selection	238738
37493140	37493163	21	-	26472758	KBM7	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-1.2914276739315196	[1633,1247]	[276,271]	-7	hSpCas9	negative selection	238739
37505328	37505351	21	+	26472758	KBM7	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.429370697702101	[496,378]	[60,88]	-7	hSpCas9	negative selection	238740
37472707	37472730	21	-	26472758	KBM7	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.6069050333337427	[1014,948]	[841,580]	6	hSpCas9	negative selection	238741
37472754	37472777	21	-	26472758	KBM7	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.4102943125841555	[780,672]	[227,281]	-4	hSpCas9	negative selection	238742
37480653	37480676	21	+	26472758	KBM7	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.5071953130374726	[551,674]	[214,197]	-4	hSpCas9	negative selection	238743
37496160	37496183	21	-	26472758	KBM7	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.7175246338101868	[478,258]	[96,107]	-5	hSpCas9	negative selection	238744
37505566	37505589	21	-	26472758	KBM7	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.3056371800465977	[1016,1272]	[325,546]	-3	hSpCas9	negative selection	238745
37472728	37472751	21	-	26472758	Raji	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.6999713866840054	[13]	[0]	-8	hSpCas9	negative selection	429854
37493102	37493125	21	-	26472758	Raji	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.5143588146223166	[436]	[70]	-4	hSpCas9	negative selection	429855
37490257	37490280	21	+	26472758	Raji	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.08024346780217184	[163]	[35]	0	hSpCas9	negative selection	429856
37493140	37493163	21	-	26472758	Raji	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-0.3437533045319767	[606]	[110]	-3	hSpCas9	negative selection	429857
37505328	37505351	21	+	26472758	Raji	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-0.8541423168117648	[147]	[18]	-6	hSpCas9	negative selection	429858
37472707	37472730	21	-	26472758	Raji	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-0.16314540700711877	[578]	[119]	-1	hSpCas9	negative selection	429859
37472754	37472777	21	-	26472758	Raji	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.3756993513283432	[368]	[65]	-3	hSpCas9	negative selection	429860
37480653	37480676	21	+	26472758	Raji	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.2862803131126773	[267]	[50]	-2	hSpCas9	negative selection	429861
37496160	37496183	21	-	26472758	Raji	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.39269006776104365	[197]	[34]	-3	hSpCas9	negative selection	429862
37505566	37505589	21	-	26472758	Raji	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.2715943005327217	[618]	[118]	-2	hSpCas9	negative selection	429863
37472728	37472751	21	-	26472758	K562	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	1.2444187276664471	[20]	[41]	9	hSpCas9	negative selection	620972
37493102	37493125	21	-	26472758	K562	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	0.12917815340965766	[507]	[468]	0	hSpCas9	negative selection	620973
37490257	37490280	21	+	26472758	K562	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.539852581278116	[371]	[107]	-6	hSpCas9	negative selection	620974
37493140	37493163	21	-	26472758	K562	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-2.870141036596409	[1047]	[120]	-8	hSpCas9	negative selection	620975
37505328	37505351	21	+	26472758	K562	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-2.6456472453007125	[340]	[45]	-8	hSpCas9	negative selection	620976
37472707	37472730	21	-	26472758	K562	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-0.41888982477445036	[1049]	[662]	-3	hSpCas9	negative selection	620977
37472754	37472777	21	-	26472758	K562	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.24279398177131878	[484]	[345]	-2	hSpCas9	negative selection	620978
37480653	37480676	21	+	26472758	K562	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.58520982340481	[717]	[201]	-7	hSpCas9	negative selection	620979
37496160	37496183	21	-	26472758	K562	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.8641057291117225	[275]	[63]	-7	hSpCas9	negative selection	620980
37505566	37505589	21	-	26472758	K562	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.011301216133029257	[904]	[757]	0	hSpCas9	negative selection	620981
37472799	37472822	21	-	26627737	DLD1	viability	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.6966197752193831	[539]	[422,170,228]	7	hSpCas9	negative selection	816161
37478224	37478247	21	-	26627737	DLD1	viability	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-1.8361297393764668	[446]	[47,58,14]	-8	hSpCas9	negative selection	816162
37480652	37480675	21	+	26627737	DLD1	viability	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-1.412368110728035	[315]	[17,49,42]	-8	hSpCas9	negative selection	816163
37486480	37486503	21	+	26627737	DLD1	viability	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.7582222861793024	[405]	[74,120,36]	-6	hSpCas9	negative selection	816164
37490257	37490280	21	+	26627737	DLD1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.1038457948894425	[157]	[27,1,35]	-7	hSpCas9	negative selection	816165
37496160	37496183	21	-	26627737	DLD1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.6051550127032694	[220]	[10,1,49]	-8	hSpCas9	negative selection	816166
37472799	37472822	21	-	26627737	GBM cells	viability after 5 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.3825930397696601	[235]	[204,124]	6	hSpCas9	negative selection	898476
37478224	37478247	21	-	26627737	GBM cells	viability after 5 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.226275855823676	[211]	[148,116]	3	hSpCas9	negative selection	898477
37480652	37480675	21	+	26627737	GBM cells	viability after 5 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.8125730259466388	[240]	[212,240]	9	hSpCas9	negative selection	898478
37486480	37486503	21	+	26627737	GBM cells	viability after 5 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.3225645044692375	[333]	[188,258]	5	hSpCas9	negative selection	898479
37490257	37490280	21	+	26627737	GBM cells	viability after 5 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.44331831645676545	[160]	[55,70]	-6	hSpCas9	negative selection	898480
37496160	37496183	21	-	26627737	GBM cells	viability after 5 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.878735992948055	[71]	[73,67]	9	hSpCas9	negative selection	898481
37472799	37472822	21	-	26627737	GBM cells	viability after 13 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.7102665079159579	[235]	[246,178]	8	hSpCas9	negative selection	980791
37478224	37478247	21	-	26627737	GBM cells	viability after 13 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.9483118027715676	[211]	[275,177]	9	hSpCas9	negative selection	980792
37480652	37480675	21	+	26627737	GBM cells	viability after 13 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	1.0144916402971385	[240]	[315,221]	9	hSpCas9	negative selection	980793
37486480	37486503	21	+	26627737	GBM cells	viability after 13 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.6299910388572176	[333]	[280,279]	7	hSpCas9	negative selection	980794
37490257	37490280	21	+	26627737	GBM cells	viability after 13 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.619091019450111	[160]	[84,33]	-6	hSpCas9	negative selection	980795
37496160	37496183	21	-	26627737	GBM cells	viability after 13 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	1.1033585199978595	[71]	[89,78]	9	hSpCas9	negative selection	980796
37472799	37472822	21	-	26627737	GBM cells	viability after 21 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.0173045181768434	[235]	[305,216]	8	hSpCas9	negative selection	1063106
37478224	37478247	21	-	26627737	GBM cells	viability after 21 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	1.5575961591343859	[211]	[349,328]	9	hSpCas9	negative selection	1063107
37480652	37480675	21	+	26627737	GBM cells	viability after 21 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	1.5559753241235905	[240]	[408,362]	9	hSpCas9	negative selection	1063108
37486480	37486503	21	+	26627737	GBM cells	viability after 21 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	1.3509818676337373	[333]	[512,416]	9	hSpCas9	negative selection	1063109
37490257	37490280	21	+	26627737	GBM cells	viability after 21 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.14840274115574353	[160]	[109,84]	1	hSpCas9	negative selection	1063110
37496160	37496183	21	-	26627737	GBM cells	viability after 21 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	2.0246020051641955	[71]	[178,140]	9	hSpCas9	negative selection	1063111
37472799	37472822	21	-	26627737	RPE1	viability after 9 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.22366146496334693	[918]	[221,482]	1	hSpCas9	negative selection	1145421
37478224	37478247	21	-	26627737	RPE1	viability after 9 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	1.0832798551427043	[491]	[290,371]	6	hSpCas9	negative selection	1145422
37480652	37480675	21	+	26627737	RPE1	viability after 9 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	1.1954785762494344	[427]	[181,467]	7	hSpCas9	negative selection	1145423
37486480	37486503	21	+	26627737	RPE1	viability after 9 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.1854122650609732	[1045]	[219,568]	1	hSpCas9	negative selection	1145424
37490257	37490280	21	+	26627737	RPE1	viability after 9 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.05756287071570648	[549]	[152,212]	0	hSpCas9	negative selection	1145425
37496160	37496183	21	-	26627737	RPE1	viability after 9 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.07928846522717437	[432]	[64,209]	0	hSpCas9	negative selection	1145426
37472799	37472822	21	-	26627737	RPE1	viability after 12 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.10297188790612516	[918]	[83,456]	0	hSpCas9	negative selection	1227736
37478224	37478247	21	-	26627737	RPE1	viability after 12 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.9336548581821542	[491]	[234,270]	6	hSpCas9	negative selection	1227737
37480652	37480675	21	+	26627737	RPE1	viability after 12 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.8733974499588365	[427]	[232,186]	5	hSpCas9	negative selection	1227738
37486480	37486503	21	+	26627737	RPE1	viability after 12 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.17903035371440837	[1045]	[119,383]	-1	hSpCas9	negative selection	1227739
37490257	37490280	21	+	26627737	RPE1	viability after 12 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.11500929926350756	[549]	[92,230]	0	hSpCas9	negative selection	1227740
37496160	37496183	21	-	26627737	RPE1	viability after 12 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.12527403596855902	[432]	[71,184]	0	hSpCas9	negative selection	1227741
37472799	37472822	21	-	26627737	RPE1	viability after 15 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.032778910148551776	[918]	[184,343]	0	hSpCas9	negative selection	1310051
37478224	37478247	21	-	26627737	RPE1	viability after 15 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	1.1696598566219718	[491]	[279,344]	6	hSpCas9	negative selection	1310052
37480652	37480675	21	+	26627737	RPE1	viability after 15 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.812077002258123	[427]	[292,134]	5	hSpCas9	negative selection	1310053
37486480	37486503	21	+	26627737	RPE1	viability after 15 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.5994637182661502	[1045]	[150,237]	-4	hSpCas9	negative selection	1310054
37490257	37490280	21	+	26627737	RPE1	viability after 15 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.5801579804474475	[549]	[43,161]	-4	hSpCas9	negative selection	1310055
37496160	37496183	21	-	26627737	RPE1	viability after 15 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.2994207609718341	[432]	[52,244]	2	hSpCas9	negative selection	1310056
37472799	37472822	21	-	26627737	RPE1	viability after 18 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-0.08739870733376834	[918]	[143,328]	0	hSpCas9	negative selection	1392366
37478224	37478247	21	-	26627737	RPE1	viability after 18 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	1.3584538818988374	[491]	[338,341]	7	hSpCas9	negative selection	1392367
37480652	37480675	21	+	26627737	RPE1	viability after 18 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.7055878424502948	[427]	[198,176]	4	hSpCas9	negative selection	1392368
37486480	37486503	21	+	26627737	RPE1	viability after 18 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.6753647757245176	[1045]	[125,230]	-4	hSpCas9	negative selection	1392369
37490257	37490280	21	+	26627737	RPE1	viability after 18 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.6827925795220757	[549]	[52,38]	-7	hSpCas9	negative selection	1392370
37496160	37496183	21	-	26627737	RPE1	viability after 18 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.40446897651283964	[432]	[81,94]	-3	hSpCas9	negative selection	1392371
37472799	37472822	21	-	26627737	HeLa	viability after 8 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.0616066416591903	[279]	[281,276,212]	7	hSpCas9	negative selection	1474681
37478224	37478247	21	-	26627737	HeLa	viability after 8 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.8406375375965509	[211]	[97,249,134]	7	hSpCas9	negative selection	1474682
37480652	37480675	21	+	26627737	HeLa	viability after 8 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.8952565127227204	[370]	[103,55,102]	-7	hSpCas9	negative selection	1474683
37486480	37486503	21	+	26627737	HeLa	viability after 8 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.36905728998139503	[240]	[261,137,40]	3	hSpCas9	negative selection	1474684
37490257	37490280	21	+	26627737	HeLa	viability after 8 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.29388698546935543	[216]	[194,28,35]	-3	hSpCas9	negative selection	1474685
37496160	37496183	21	-	26627737	HeLa	viability after 8 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.8306937831125858	[290]	[47,32,28]	-9	hSpCas9	negative selection	1474686
37472799	37472822	21	-	26627737	HeLa	viability after 12 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.226489335745955	[279]	[526,107,201]	8	hSpCas9	negative selection	1556996
37478224	37478247	21	-	26627737	HeLa	viability after 12 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	1.0785684426126387	[211]	[323,157,79]	7	hSpCas9	negative selection	1556997
37480652	37480675	21	+	26627737	HeLa	viability after 12 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.20464359936776017	[370]	[317,149,68]	1	hSpCas9	negative selection	1556998
37486480	37486503	21	+	26627737	HeLa	viability after 12 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.7368598729452777	[240]	[229,116,157]	6	hSpCas9	negative selection	1556999
37490257	37490280	21	+	26627737	HeLa	viability after 12 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.09170497495793217	[216]	[113,58,82]	-1	hSpCas9	negative selection	1557000
37496160	37496183	21	-	26627737	HeLa	viability after 12 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.1876262102057573	[290]	[14,64,75]	-8	hSpCas9	negative selection	1557001
37472799	37472822	21	-	26627737	HeLa	viability after 15 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.0511523509276617	[279]	[162,135,424]	7	hSpCas9	negative selection	1639311
37478224	37478247	21	-	26627737	HeLa	viability after 15 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.631861181497601	[211]	[68,223,106]	5	hSpCas9	negative selection	1639312
37480652	37480675	21	+	26627737	HeLa	viability after 15 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.5039648040985549	[370]	[152,154,2]	-4	hSpCas9	negative selection	1639313
37486480	37486503	21	+	26627737	HeLa	viability after 15 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.39370051595025096	[240]	[163,71,151]	3	hSpCas9	negative selection	1639314
37490257	37490280	21	+	26627737	HeLa	viability after 15 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.6197591296759937	[216]	[12,49,22]	-8	hSpCas9	negative selection	1639315
37496160	37496183	21	-	26627737	HeLa	viability after 15 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.8769885093511449	[290]	[29,98,64]	-6	hSpCas9	negative selection	1639316
37472799	37472822	21	-	26627737	HeLa	viability after 18 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.0653475787767337	[279]	[115,109,424]	7	hSpCas9	negative selection	1721626
37478224	37478247	21	-	26627737	HeLa	viability after 18 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.6011510410308567	[211]	[45,178,106]	5	hSpCas9	negative selection	1721627
37480652	37480675	21	+	26627737	HeLa	viability after 18 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.4609708232186593	[370]	[105,131,2]	-4	hSpCas9	negative selection	1721628
37486480	37486503	21	+	26627737	HeLa	viability after 18 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.4044038989726001	[240]	[109,61,151]	3	hSpCas9	negative selection	1721629
37490257	37490280	21	+	26627737	HeLa	viability after 18 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.6522086384773287	[216]	[6,41,22]	-8	hSpCas9	negative selection	1721630
37496160	37496183	21	-	26627737	HeLa	viability after 18 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.953835930274755	[290]	[15,78,64]	-7	hSpCas9	negative selection	1721631
37472799	37472822	21	-	26627737	HCT116	viability after 6 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.6982429866830576	[890]	[205,238]	4	hSpCas9	negative selection	1803941
37478224	37478247	21	-	26627737	HCT116	viability after 6 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.20026518778755664	[353]	[168,5]	1	hSpCas9	negative selection	1803942
37480652	37480675	21	+	26627737	HCT116	viability after 6 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.5646683318394156	[441]	[270,9]	3	hSpCas9	negative selection	1803943
37486480	37486503	21	+	26627737	HCT116	viability after 6 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-1.1861949192583419	[640]	[71,28]	-6	hSpCas9	negative selection	1803944
37490257	37490280	21	+	26627737	HCT116	viability after 6 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	1.2844054281958384	[182]	[13,100]	7	hSpCas9	negative selection	1803945
37496160	37496183	21	-	26627737	HCT116	viability after 6 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.1424842959596186	[194]	[29,4]	-6	hSpCas9	negative selection	1803946
37472799	37472822	21	-	26627737	HCT116	viability after 8 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-0.374480385274203	[344]	[166,184,88]	-4	hSpCas9	negative selection	1886256
37478224	37478247	21	-	26627737	HCT116	viability after 8 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-0.330795938349828	[222]	[96,90,104]	-4	hSpCas9	negative selection	1886257
37480652	37480675	21	+	26627737	HCT116	viability after 8 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.19601305628642016	[230]	[97,144,192]	2	hSpCas9	negative selection	1886258
37486480	37486503	21	+	26627737	HCT116	viability after 8 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.05809043058531607	[352]	[229,203,127]	0	hSpCas9	negative selection	1886259
37490257	37490280	21	+	26627737	HCT116	viability after 8 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.942797225803607	[219]	[56,61,69]	-8	hSpCas9	negative selection	1886260
37496160	37496183	21	-	26627737	HCT116	viability after 8 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.9805978266868551	[208]	[64,34,74]	-8	hSpCas9	negative selection	1886261
37472799	37472822	21	-	26627737	HCT116	viability after 9 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-1.6528776036835424	[890]	[97,57]	-8	hSpCas9	negative selection	1968571
37478224	37478247	21	-	26627737	HCT116	viability after 9 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-0.9874342588009581	[353]	[45,48]	-6	hSpCas9	negative selection	1968572
37480652	37480675	21	+	26627737	HCT116	viability after 9 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	1.7180716344757538	[441]	[251,495]	9	hSpCas9	negative selection	1968573
37486480	37486503	21	+	26627737	HCT116	viability after 9 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.15917186285453572	[640]	[121,177]	-1	hSpCas9	negative selection	1968574
37490257	37490280	21	+	26627737	HCT116	viability after 9 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.23708062505659022	[182]	[79,10]	-2	hSpCas9	negative selection	1968575
37496160	37496183	21	-	26627737	HCT116	viability after 9 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.6650532695319487	[194]	[0,57]	-5	hSpCas9	negative selection	1968576
37472799	37472822	21	-	26627737	HCT116	viability after 12 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.1022003642420932	[344]	[123,274,192]	1	hSpCas9	negative selection	2050886
37478224	37478247	21	-	26627737	HCT116	viability after 12 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-0.49542002819029707	[222]	[123,49,70]	-5	hSpCas9	negative selection	2050887
37480652	37480675	21	+	26627737	HCT116	viability after 12 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.2469006684238806	[230]	[116,76,110]	-3	hSpCas9	negative selection	2050888
37486480	37486503	21	+	26627737	HCT116	viability after 12 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.019575823963574046	[352]	[215,159,184]	0	hSpCas9	negative selection	2050889
37490257	37490280	21	+	26627737	HCT116	viability after 12 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.1968380748970295	[219]	[28,11,33]	-9	hSpCas9	negative selection	2050890
37496160	37496183	21	-	26627737	HCT116	viability after 12 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.513491063374542	[208]	[17,70,28]	-9	hSpCas9	negative selection	2050891
37472799	37472822	21	-	26627737	HCT116	viability after 15 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.14425426672076272	[344]	[227,210,218]	1	hSpCas9	negative selection	2133201
37478224	37478247	21	-	26627737	HCT116	viability after 15 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-1.0386886925637762	[222]	[83,71,33]	-8	hSpCas9	negative selection	2133202
37480652	37480675	21	+	26627737	HCT116	viability after 15 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.7153820755252172	[230]	[122,82,41]	-6	hSpCas9	negative selection	2133203
37486480	37486503	21	+	26627737	HCT116	viability after 15 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.1335883118551655	[352]	[181,182,188]	-1	hSpCas9	negative selection	2133204
37490257	37490280	21	+	26627737	HCT116	viability after 15 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.1964668911248533	[219]	[41,83,37]	-8	hSpCas9	negative selection	2133205
37496160	37496183	21	-	26627737	HCT116	viability after 15 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.6609042504483575	[208]	[17,34,3]	-9	hSpCas9	negative selection	2133206
37472799	37472822	21	-	26627737	HCT116	viability after 18 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.3913465743196405	[344]	[133,238,284]	3	hSpCas9	negative selection	2215516
37478224	37478247	21	-	26627737	HCT116	viability after 18 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-1.281940369304278	[222]	[53,48,28]	-8	hSpCas9	negative selection	2215517
37480652	37480675	21	+	26627737	HCT116	viability after 18 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.6148511597282645	[230]	[73,61,83]	-5	hSpCas9	negative selection	2215518
37486480	37486503	21	+	26627737	HCT116	viability after 18 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.3816284076751664	[352]	[270,210,183]	3	hSpCas9	negative selection	2215519
37490257	37490280	21	+	26627737	HCT116	viability after 18 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.9813070107247928	[219]	[34,21,23]	-9	hSpCas9	negative selection	2215520
37496160	37496183	21	-	26627737	HCT116	viability after 18 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.3225348769492173	[208]	[43,6,9]	-9	hSpCas9	negative selection	2215521
37420363	37420386	21	+	24336569	HL60	viability	TGAAAGAAGACGATGCATACAGG	DYRK1A	ENSG00000157540	0.5550995965794723	[118]	[369]	5	hSpCas9	negative selection	2261759
37472699	37472722	21	+	24336569	HL60	viability	CATGCAAACCTTCATCTGTTCGG	DYRK1A	ENSG00000157540	0.1345305495094008	[225]	[524]	1	hSpCas9	negative selection	2261760
37472707	37472730	21	-	24336569	HL60	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.20442824734997012	[980]	[2391]	2	hSpCas9	negative selection	2261761
37472742	37472765	21	+	24336569	HL60	viability	CCATGCTGCTGGCCTTCAGATGG	DYRK1A	ENSG00000157540	-0.11988286348696753	[703]	[1370]	-1	hSpCas9	negative selection	2261762
37472754	37472777	21	-	24336569	HL60	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.58646497679546	[793]	[1118]	-5	hSpCas9	negative selection	2261763
37472777	37472800	21	-	24336569	HL60	viability	GTCACTGTACTGATGTGAATGGG	DYRK1A	ENSG00000157540	0.8149487131723461	[432]	[1611]	6	hSpCas9	negative selection	2261764
37472799	37472822	21	-	24336569	HL60	viability	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.0029115378500468	[742]	[3150]	7	hSpCas9	negative selection	2261765
37472805	37472828	21	-	24336569	HL60	viability	GTTGGTCACTTATGTTTGGCTGG	DYRK1A	ENSG00000157540	0.11767104583794927	[401]	[922]	1	hSpCas9	negative selection	2261766
37472823	37472846	21	-	24336569	HL60	viability	ATGATAAGGCAGAAACCTGTTGG	DYRK1A	ENSG00000157540	-0.33583470727725184	[1626]	[2727]	-3	hSpCas9	negative selection	2261767
37472837	37472860	21	-	24336569	HL60	viability	AATCTGGTCAGAATATGATAAGG	DYRK1A	ENSG00000157540	-0.03293955020421624	[686]	[1420]	0	hSpCas9	negative selection	2261768
37420363	37420386	21	+	24336569	KBM7	viability	TGAAAGAAGACGATGCATACAGG	DYRK1A	ENSG00000157540	1.3401469187597892	[147]	[1021]	9	hSpCas9	negative selection	2328936
37472699	37472722	21	+	24336569	KBM7	viability	CATGCAAACCTTCATCTGTTCGG	DYRK1A	ENSG00000157540	-0.6696833383277943	[416]	[714]	-5	hSpCas9	negative selection	2328937
37472707	37472730	21	-	24336569	KBM7	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-0.14501642652845148	[1004]	[2478]	-1	hSpCas9	negative selection	2328938
37472742	37472765	21	+	24336569	KBM7	viability	CCATGCTGCTGGCCTTCAGATGG	DYRK1A	ENSG00000157540	0.899131999268368	[403]	[2054]	7	hSpCas9	negative selection	2328939
37472754	37472777	21	-	24336569	KBM7	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-1.228781830750518	[573]	[667]	-7	hSpCas9	negative selection	2328940
37472777	37472800	21	-	24336569	KBM7	viability	GTCACTGTACTGATGTGAATGGG	DYRK1A	ENSG00000157540	0.02761017021040768	[595]	[1656]	0	hSpCas9	negative selection	2328941
37472799	37472822	21	-	24336569	KBM7	viability	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.5437201880386167	[789]	[3140]	5	hSpCas9	negative selection	2328942
37472805	37472828	21	-	24336569	KBM7	viability	GTTGGTCACTTATGTTTGGCTGG	DYRK1A	ENSG00000157540	0.16006052431336315	[525]	[1602]	1	hSpCas9	negative selection	2328943
37472823	37472846	21	-	24336569	KBM7	viability	ATGATAAGGCAGAAACCTGTTGG	DYRK1A	ENSG00000157540	0.011321336111171698	[1234]	[3394]	0	hSpCas9	negative selection	2328944
37472837	37472860	21	-	24336569	KBM7	viability	AATCTGGTCAGAATATGATAAGG	DYRK1A	ENSG00000157540	1.16175887944161	[312]	[1909]	8	hSpCas9	negative selection	2328945
37410634	37410657	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGGGGAGGCTGAGGTGGGAAG	DYRK1A	ENSG00000157540	1.9136723579629027	[11,4]	[10,2]	6	dCas9-VP64	positive selection	2383702
37377160	37377183	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCTTGG	DYRK1A	ENSG00000157540	0.12883397399525423	[86,65]	[25,8]	0	dCas9-VP64	positive selection	2424695
37420034	37420057	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAATACCTGAAATTTTCCGTGG	DYRK1A	ENSG00000157540	-0.9961948867987128	[88,215]	[22,9]	-6	dCas9-VP64	positive selection	2427841
37419995	37420018	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTAAATGGTGGAATATTCAGG	DYRK1A	ENSG00000157540	-1.0259556275679906	[1230,508]	[164,14]	-6	dCas9-VP64	positive selection	2427842
37420040	37420063	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTATTACCACGGAAAATTTCAGG	DYRK1A	ENSG00000157540	0.9166978464552455	[276,79]	[20,128]	4	dCas9-VP64	positive selection	2427843
37367468	37367491	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGACTGAGCAGGCTGCGGCGCGG	DYRK1A	ENSG00000157540	2.116322697749411	[22,15]	[11,25]	7	dCas9-VP64	positive selection	2463032
37367444	37367467	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTCGGCTCGCGGTTCCAGCGG	DYRK1A	ENSG00000157540	-1.3811810419839727	[372,74]	[34,0]	-7	dCas9-VP64	positive selection	2463033
37367397	37367420	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGGTATTTGCCGGGGAGGGGG	DYRK1A	ENSG00000157540	1.8381466026737971	[0,0]	[0,0]	6	dCas9-VP64	positive selection	2463034
37418784	37418807	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACTAGACCTACAACTAGCTGG	DYRK1A	ENSG00000157540	2.1788295993406743	[72,16]	[51,36]	7	dCas9-VP64	positive selection	2463050
37418752	37418775	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGGGGGTGTATGACTAGATGG	DYRK1A	ENSG00000157540	0.5722355943839097	[66,27]	[17,11]	2	dCas9-VP64	positive selection	2463051
37418805	37418828	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTTAATGTAATACCGTAACAGG	DYRK1A	ENSG00000157540	2.8226315345029946	[13,105]	[1,195]	8	dCas9-VP64	positive selection	2463052
37479730	37479753	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGCTGAGGCAGGAGAAAGG	DYRK1A	ENSG00000157540	1.7244712313844854	[32,17]	[27,7]	6	dCas9-VP64	positive selection	2468608
37483705	37483728	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCTAG	DYRK1A	ENSG00000157540	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468646
37448954	37448977	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGTTGGGATTACAGG	DYRK1A	ENSG00000157540	-0.9779924112879362	[118,144]	[22,4]	-6	dCas9-VP64	positive selection	2469573
37470026	37470049	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTCCTCGGGAGGCTGAGG	DYRK1A	ENSG00000157540	-0.2571104693801929	[13,2]	[1,0]	-1	dCas9-VP64	positive selection	2474853
37410634	37410657	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGGGGAGGCTGAGGTGGGAAG	DYRK1A	ENSG00000157540	-0.0414745702136492	[20,132]	[18,27]	0	dCas9-VP64	positive selection	2478957
37377160	37377183	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCTTGG	DYRK1A	ENSG00000157540	-0.30672599620467045	[261,149]	[50,57]	-3	dCas9-VP64	positive selection	2519950
37420034	37420057	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAATACCTGAAATTTTCCGTGG	DYRK1A	ENSG00000157540	0.6821472753180222	[177,211]	[135,70]	5	dCas9-VP64	positive selection	2523096
37419995	37420018	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTAAATGGTGGAATATTCAGG	DYRK1A	ENSG00000157540	-0.32838472321234247	[485,256]	[102,90]	-3	dCas9-VP64	positive selection	2523097
37420040	37420063	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTATTACCACGGAAAATTTCAGG	DYRK1A	ENSG00000157540	1.7941830797751825	[63,99]	[33,146]	8	dCas9-VP64	positive selection	2523098
37367468	37367491	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGACTGAGCAGGCTGCGGCGCGG	DYRK1A	ENSG00000157540	-0.5294972659680308	[134,113]	[27,27]	-5	dCas9-VP64	positive selection	2558287
37367444	37367467	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTCGGCTCGCGGTTCCAGCGG	DYRK1A	ENSG00000157540	-0.0009460047733960142	[357,412]	[219,36]	0	dCas9-VP64	positive selection	2558288
37367397	37367420	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGGTATTTGCCGGGGAGGGGG	DYRK1A	ENSG00000157540	-0.19637869902270877	[14,31]	[8,3]	-2	dCas9-VP64	positive selection	2558289
37418784	37418807	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACTAGACCTACAACTAGCTGG	DYRK1A	ENSG00000157540	-0.6288893117385459	[21,164]	[6,29]	-6	dCas9-VP64	positive selection	2558305
37418752	37418775	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGGGGGTGTATGACTAGATGG	DYRK1A	ENSG00000157540	-0.19691063865800618	[102,40]	[30,9]	-2	dCas9-VP64	positive selection	2558306
37418805	37418828	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTTAATGTAATACCGTAACAGG	DYRK1A	ENSG00000157540	-0.641301910979861	[241,55]	[52,9]	-6	dCas9-VP64	positive selection	2558307
37479730	37479753	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGCTGAGGCAGGAGAAAGG	DYRK1A	ENSG00000157540	-0.1093774260535414	[64,117]	[17,35]	-1	dCas9-VP64	positive selection	2563863
37483705	37483728	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCTAG	DYRK1A	ENSG00000157540	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563901
37448954	37448977	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGTTGGGATTACAGG	DYRK1A	ENSG00000157540	0.3469774473649052	[51,34]	[26,8]	3	dCas9-VP64	positive selection	2564828
37470026	37470049	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTCCTCGGGAGGCTGAGG	DYRK1A	ENSG00000157540	0.5230605474514848	[120,26]	[20,47]	4	dCas9-VP64	positive selection	2570108
37478192	37478215	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	0.2467277048481871	[3,3]	[3,4]	5	hSpCas9	positive selection	2984809
37480688	37480711	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	0.3627058509117489	[4,3]	[1,6]	7	hSpCas9	positive selection	2984810
37490258	37490281	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.08415421653771005	[4,4]	[2,4]	1	hSpCas9	positive selection	2984811
37490188	37490211	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.2833389162892099	[3,3]	[2,2]	-4	hSpCas9	positive selection	2984812
37478192	37478215	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	-0.011335168302166979	[3,3]	[2,2]	0	hSpCas9	positive selection	3052667
37480688	37480711	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	0.278014178568873	[4,4]	[5,2]	5	hSpCas9	positive selection	3052668
37490258	37490281	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.7238508752321781	[4,4]	[3,0]	-8	hSpCas9	positive selection	3052669
37490188	37490211	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.1695662236496971	[3,3]	[3,1]	-2	hSpCas9	positive selection	3052670
37472809	37472832		-	24336571	A375	resistance to PLX after 7 days	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	-0.01605420393053736	[114,120]	[119,111]	0	hSpCas9	positive selection	3111006
37480682	37480705		+	24336571	A375	resistance to PLX after 7 days	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.5525768706083941	[10,10]	[7,6]	-9	hSpCas9	positive selection	3111007
37480816	37480839		-	24336571	A375	resistance to PLX after 7 days	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	-0.0978338593644178	[26,24]	[26,20]	-3	hSpCas9	positive selection	3111008
37472809	37472832		-	24336571	A375	resistance to PLX after 14 days	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	0.15116000550280173	[116,115]	[59,60]	1	hSpCas9	positive selection	3168799
37480682	37480705		+	24336571	A375	resistance to PLX after 14 days	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.5860679635582645	[7,10]	[1,2]	-7	hSpCas9	positive selection	3168800
37480816	37480839		-	24336571	A375	resistance to PLX after 14 days	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	0.10631682482781357	[24,19]	[9,11]	1	hSpCas9	positive selection	3168801
37472809	37472832		-	24336571	A375	viability after 7 days	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	0.5858210060078171	[82]	[114,120]	8	hSpCas9	negative selection	3226592
37480682	37480705		+	24336571	A375	viability after 7 days	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.6329100712410605	[17]	[10,10]	-7	hSpCas9	negative selection	3226593
37480816	37480839		-	24336571	A375	viability after 7 days	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	-0.8194114910641691	[48]	[26,24]	-8	hSpCas9	negative selection	3226594
37472809	37472832		-	24336571	A375	viability after 14 days	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	0.5856528181983527	[82]	[116,115]	7	hSpCas9	negative selection	3284385
37480682	37480705		+	24336571	A375	viability after 14 days	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.8711724723401941	[17]	[7,10]	-8	hSpCas9	negative selection	3284386
37480816	37480839		-	24336571	A375	viability after 14 days	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	-1.021918240376304	[48]	[24,19]	-8	hSpCas9	negative selection	3284387
37480676	37480699	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.09463785243239854	[142,183]	[0,0]	0	hSpCas9	positive selection	3347224
37486469	37486492	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	2.0118822500717424	[27,47]	[0,0]	7	hSpCas9	positive selection	3347225
37472859	37472882	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	1.2436888035219165	[80,47]	[0,0]	5	hSpCas9	positive selection	3347226
37472866	37472889	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.5042250209986441	[216,216]	[0,0]	-3	hSpCas9	positive selection	3366423
37480682	37480705	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3366424
37486593	37486616	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3366425
37478191	37478214	21	+	26780180	HT29	viability (Avana library 4 designs)	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	1.68001092788698	[]	[]	6	hSpCas9	negative selection	3421614
37480687	37480710	21	+	26780180	HT29	viability (Avana library 4 designs)	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	-0.319143186922625	[]	[]	-5	hSpCas9	negative selection	3421615
37490257	37490280	21	+	26780180	HT29	viability (Avana library 4 designs)	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.974309388509796	[]	[]	4	hSpCas9	negative selection	3421616
37490188	37490211	21	-	26780180	HT29	viability (Avana library 4 designs)	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	1.57857447785305	[]	[]	6	hSpCas9	negative selection	3421617
37490257	37490280	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-4.48413745508989	[]	[]	-5	hSpCas9	negative selection	3501864
37490188	37490211	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-5.87634519245087	[]	[]	-6	hSpCas9	negative selection	3501865
37480687	37480710	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	-15.6772505586038	[]	[]	-9	hSpCas9	negative selection	3501866
37478191	37478214	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	-6.45420881016751	[]	[]	-6	hSpCas9	negative selection	3501867
37490272	37490295	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGGTTCAAAGAGACCCCTCGG	DYRK1A	ENSG00000157540	-1.95395247763728	[]	[]	-2	hSpCas9	negative selection	3501868
37490256	37490279	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	-6.70889930791342	[]	[]	-6	hSpCas9	negative selection	3501869
37490257	37490280	21	+	26780180	A375	viability (Avana lentiGuide)	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	9.47337812249947	[]	[]	6	hSpCas9	negative selection	3610523
37490188	37490211	21	-	26780180	A375	viability (Avana lentiGuide)	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	7.08571057015379	[]	[]	5	hSpCas9	negative selection	3610524
37480687	37480710	21	+	26780180	A375	viability (Avana lentiGuide)	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	0.1192786977006	[]	[]	0	hSpCas9	negative selection	3610525
37478191	37478214	21	+	26780180	A375	viability (Avana lentiGuide)	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	-2.29792456839111	[]	[]	-4	hSpCas9	negative selection	3610526
37490272	37490295	21	-	26780180	A375	viability (Avana lentiGuide)	TTAGGTTCAAAGAGACCCCTCGG	DYRK1A	ENSG00000157540	-1.51085785388457	[]	[]	-2	hSpCas9	negative selection	3610527
37490256	37490279	21	+	26780180	A375	viability (Avana lentiGuide)	TGAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.84035871162269	[]	[]	1	hSpCas9	negative selection	3610528
37490257	37490280	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.2239600965598814	[4]	[4,3]	-4	hSpCas9	positive selection	3719182
37490188	37490211	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.8406828273365826	[5]	[1,3]	-8	hSpCas9	positive selection	3719183
37480687	37480710	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	-1.1126604186126194	[8]	[3,2]	-9	hSpCas9	positive selection	3719184
37478191	37478214	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	-0.5068855214868465	[6]	[3,4]	-6	hSpCas9	positive selection	3719185
37490272	37490295	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGGTTCAAAGAGACCCCTCGG	DYRK1A	ENSG00000157540	-0.17668326506794657	[5]	[5,4]	-3	hSpCas9	positive selection	3719186
37490256	37490279	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	-0.7099926456641893	[5]	[3,2]	-7	hSpCas9	positive selection	3719187
37490257	37490280	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.26989536593749963	[4]	[5,4]	7	hSpCas9	positive selection	3827789
37490188	37490211	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.44517499534443206	[5]	[4,0]	-5	hSpCas9	positive selection	3827790
37480687	37480710	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTAGTCATAAGAAGGAACGG	DYRK1A	ENSG00000157540	0.09789605953340073	[5]	[6,3]	2	hSpCas9	positive selection	3827791
37478191	37478214	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATTGTCATGTTACAGAGGCGG	DYRK1A	ENSG00000157540	0.02297235046493279	[5]	[4,3]	0	hSpCas9	positive selection	3827792
37490272	37490295	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGGTTCAAAGAGACCCCTCGG	DYRK1A	ENSG00000157540	-0.001329223682991515	[5]	[5,3]	0	hSpCas9	positive selection	3827793
37490256	37490279	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.11784315863450986	[5]	[5,4]	2	hSpCas9	positive selection	3827794
37486593	37486616	21	+	26780180	A375	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	1.69830096178243	[]	[]	9	hSpCas9	negative selection	3935197
37480682	37480705	21	+	26780180	A375	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.969781495463096	[]	[]	4	hSpCas9	negative selection	3935198
37472866	37472889	21	-	26780180	A375	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	1.25807188137295	[]	[]	6	hSpCas9	negative selection	3935199
37480676	37480699	21	-	26780180	A375	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	2.40365157862415	[]	[]	9	hSpCas9	negative selection	3935200
37472859	37472882	21	+	26780180	A375	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	1.28348190920169	[]	[]	7	hSpCas9	negative selection	3935201
37486469	37486492	21	+	26780180	A375	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	1.40917880542549	[]	[]	7	hSpCas9	negative selection	3935202
37486593	37486616	21	+	26780180	HT29	viability (GeCKOv2 library)	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	1.5426923596673	[]	[]	7	hSpCas9	negative selection	4043163
37480682	37480705	21	+	26780180	HT29	viability (GeCKOv2 library)	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	1.28936691553495	[]	[]	6	hSpCas9	negative selection	4043164
37472866	37472889	21	-	26780180	HT29	viability (GeCKOv2 library)	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.127085156869941	[]	[]	-4	hSpCas9	negative selection	4043165
37480676	37480699	21	-	26780180	HT29	viability (GeCKOv2 library)	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	1.18669693768403	[]	[]	6	hSpCas9	negative selection	4043166
37472859	37472882	21	+	26780180	HT29	viability (GeCKOv2 library)	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	1.07266320132165	[]	[]	5	hSpCas9	negative selection	4043167
37486469	37486492	21	+	26780180	HT29	viability (GeCKOv2 library)	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	1.08599243939665	[]	[]	5	hSpCas9	negative selection	4043168
37472809	37472832	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	0.29953970173430233	[6]	[5,5]	7	hSpCas9	positive selection	4133587
37480682	37480705	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.35159324675159326	[3]	[2,0]	-7	hSpCas9	positive selection	4133588
37480816	37480839	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	-0.04313003730750686	[4]	[2,3]	-1	hSpCas9	positive selection	4133589
37472809	37472832	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGTTGGTCACTTATGTTTGG	DYRK1A	ENSG00000157540	1.0151800376611537	[6]	[5,6,5,5]	7	hSpCas9	positive selection	4197609
37480682	37480705	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.17879619552786022	[4]	[3,5,0,0]	1	hSpCas9	positive selection	4197610
37480816	37480839	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATTAAATTACCTGTCCAAAGG	DYRK1A	ENSG00000157540	-0.5407891743922888	[5]	[2,2,1,0]	-7	hSpCas9	positive selection	4197611
37480676	37480699	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.2828473070611424	[3]	[3,1]	-5	hSpCas9	positive selection	4267960
37486469	37486492	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.5418144426795961	[2]	[1,0]	-8	hSpCas9	positive selection	4267961
37472859	37472882	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	-0.4023853118755358	[2]	[0,0]	-7	hSpCas9	positive selection	4267962
37472866	37472889	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.2547041428101083	[2]	[2,0]	-5	hSpCas9	positive selection	4332226
37480682	37480705	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.48890237148721316	[1]	[0,0]	-8	hSpCas9	positive selection	4332227
37486593	37486616	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.08543457958202393	[3]	[2,2]	-2	hSpCas9	positive selection	4332228
37472799	37472821	21	-	27760321	OCIAML3	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.06811381187838128	[683,588]	[568,456]	0	hSpCas9	negative selection	4396372
37480683	37480705	21	+	27760321	OCIAML3	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-2.1367142657185934	[106,73]	[11,20]	-9	hSpCas9	negative selection	4396373
37486482	37486504	21	+	27760321	OCIAML3	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	-1.6468424229878615	[308,279]	[56,94]	-8	hSpCas9	negative selection	4396374
37490188	37490210	21	-	27760321	OCIAML3	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-2.4250192635612997	[8,15]	[0,2]	-9	hSpCas9	negative selection	4396375
37490257	37490279	21	+	27760321	OCIAML3	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.5320083365953282	[317,263]	[354,291]	6	hSpCas9	negative selection	4396376
37472799	37472821	21	-	27760321	OCIAML2	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.6228417553591393	[683,588]	[674,942]	8	hSpCas9	negative selection	4479835
37480683	37480705	21	+	27760321	OCIAML2	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-1.0985829750388096	[106,73]	[22,47]	-8	hSpCas9	negative selection	4479836
37486482	37486504	21	+	27760321	OCIAML2	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	-3.071663172336709	[308,279]	[23,33]	-9	hSpCas9	negative selection	4479837
37490188	37490210	21	-	27760321	OCIAML2	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-3.3754095568477744	[8,15]	[0,0]	-9	hSpCas9	negative selection	4479838
37490257	37490279	21	+	27760321	OCIAML2	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	-0.5826042315425953	[317,263]	[143,172]	-6	hSpCas9	negative selection	4479839
37472799	37472821	21	-	27760321	MV411	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.6516059810767328	[683,588]	[599,744]	5	hSpCas9	negative selection	4563298
37480683	37480705	21	+	27760321	MV411	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-5.8832143916156365	[106,73]	[0,0]	-9	hSpCas9	negative selection	4563299
37486482	37486504	21	+	27760321	MV411	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	-0.20286691210350494	[308,279]	[71,313]	-1	hSpCas9	negative selection	4563300
37490188	37490210	21	-	27760321	MV411	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.45032107485846673	[8,15]	[0,13]	-3	hSpCas9	negative selection	4563301
37490257	37490279	21	+	27760321	MV411	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	-1.3237830634369003	[317,263]	[53,109]	-7	hSpCas9	negative selection	4563302
37472799	37472821	21	-	27760321	HL60	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.4325652304452857	[683,588]	[690,708]	5	hSpCas9	negative selection	4646761
37480683	37480705	21	+	27760321	HL60	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.06681609324555682	[106,73]	[93,57]	0	hSpCas9	negative selection	4646762
37486482	37486504	21	+	27760321	HL60	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.004368493047563815	[308,279]	[128,359]	0	hSpCas9	negative selection	4646763
37490188	37490210	21	-	27760321	HL60	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-1.3581078404745446	[8,15]	[6,0]	-8	hSpCas9	negative selection	4646764
37490257	37490279	21	+	27760321	HL60	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.3688279156345543	[317,263]	[342,265]	4	hSpCas9	negative selection	4646765
37472799	37472821	21	-	27760321	HT1080	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	1.8575528106418502	[588,459]	[856,647]	8	hSpCas9	negative selection	4730224
37480683	37480705	21	+	27760321	HT1080	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.7567990484140508	[73,57]	[0,91]	4	hSpCas9	negative selection	4730225
37486482	37486504	21	+	27760321	HT1080	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	2.2365967887412084	[279,218]	[267,687]	9	hSpCas9	negative selection	4730226
37490188	37490210	21	-	27760321	HT1080	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	5.228138578713851	[15,12]	[312,111]	9	hSpCas9	negative selection	4730227
37490257	37490279	21	+	27760321	HT1080	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	2.763924769813172	[263,205]	[548,730]	9	hSpCas9	negative selection	4730228
37472799	37472821	21	-	27760321	HT29	viability after 7 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.2479921391519364	[588,459]	[1080,610,750]	4	hSpCas9	negative selection	4813687
37480683	37480705	21	+	27760321	HT29	viability after 7 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	1.2179683586846168	[73,57]	[147,175,258]	9	hSpCas9	negative selection	4813688
37486482	37486504	21	+	27760321	HT29	viability after 7 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.568055567039744	[279,218]	[528,402,500]	8	hSpCas9	negative selection	4813689
37490188	37490210	21	-	27760321	HT29	viability after 7 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.2753152426723151	[15,12]	[2,40,0]	-4	hSpCas9	negative selection	4813690
37490257	37490279	21	+	27760321	HT29	viability after 7 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.4772814663783831	[263,205]	[415,532,314]	7	hSpCas9	negative selection	4813691
37472799	37472821	21	-	27760321	HT29	viability after 25 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.6883190859159622	[588,459]	[980,1037,865]	7	hSpCas9	negative selection	4897150
37480683	37480705	21	+	27760321	HT29	viability after 25 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.848396704518382	[73,57]	[38,155,227]	8	hSpCas9	negative selection	4897151
37486482	37486504	21	+	27760321	HT29	viability after 25 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.5917559447413081	[279,218]	[526,433,308]	6	hSpCas9	negative selection	4897152
37490188	37490210	21	-	27760321	HT29	viability after 25 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.11143789145616712	[15,12]	[40,0,0]	-1	hSpCas9	negative selection	4897153
37490257	37490279	21	+	27760321	HT29	viability after 25 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.006214460693367174	[263,205]	[236,267,309]	0	hSpCas9	negative selection	4897154
37472799	37472821	21	-	27760321	HT29	viability after 22 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.5509042375939679	[588,459]	[1018,1009,629]	6	hSpCas9	negative selection	4980613
37480683	37480705	21	+	27760321	HT29	viability after 22 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.7393685901068394	[73,57]	[141,94,144]	8	hSpCas9	negative selection	4980614
37486482	37486504	21	+	27760321	HT29	viability after 22 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.003016624235633758	[279,218]	[203,325,339]	0	hSpCas9	negative selection	4980615
37490188	37490210	21	-	27760321	HT29	viability after 22 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	1.951297768715456	[15,12]	[188,0,0]	9	hSpCas9	negative selection	4980616
37490257	37490279	21	+	27760321	HT29	viability after 22 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.37730283237951834	[263,205]	[362,376,317]	4	hSpCas9	negative selection	4980617
37472799	37472821	21	-	27760321	HT29	viability after 19 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.0749304944558612	[588,459]	[751,530,624]	0	hSpCas9	negative selection	5064076
37480683	37480705	21	+	27760321	HT29	viability after 19 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.6449650111883811	[73,57]	[239,38,88]	6	hSpCas9	negative selection	5064077
37486482	37486504	21	+	27760321	HT29	viability after 19 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.3457650263522313	[279,218]	[376,368,343]	3	hSpCas9	negative selection	5064078
37490188	37490210	21	-	27760321	HT29	viability after 19 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.9977308395783338	[15,12]	[24,0,0]	-6	hSpCas9	negative selection	5064079
37490257	37490279	21	+	27760321	HT29	viability after 19 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.597143749603455	[263,205]	[443,390,388]	6	hSpCas9	negative selection	5064080
37472799	37472821	21	-	27760321	HT29	viability after 16 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.27323504612121574	[588,459]	[627,663,828]	3	hSpCas9	negative selection	5147539
37480683	37480705	21	+	27760321	HT29	viability after 16 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	1.3527706304576093	[73,57]	[250,256,61]	9	hSpCas9	negative selection	5147540
37486482	37486504	21	+	27760321	HT29	viability after 16 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.3968499511841745	[279,218]	[523,307,286]	4	hSpCas9	negative selection	5147541
37490188	37490210	21	-	27760321	HT29	viability after 16 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	0.9991748916131571	[15,12]	[102,0,0]	9	hSpCas9	negative selection	5147542
37490257	37490279	21	+	27760321	HT29	viability after 16 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.43259583747797015	[263,205]	[501,292,284]	5	hSpCas9	negative selection	5147543
37472799	37472821	21	-	27760321	HT29	viability after 13 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.0644033078520545	[588,459]	[499,737,668]	0	hSpCas9	negative selection	5231002
37480683	37480705	21	+	27760321	HT29	viability after 13 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.5630889260596226	[73,57]	[91,91,152]	7	hSpCas9	negative selection	5231003
37486482	37486504	21	+	27760321	HT29	viability after 13 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.6891203862993984	[279,218]	[632,474,301]	8	hSpCas9	negative selection	5231004
37490188	37490210	21	-	27760321	HT29	viability after 13 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-1.9812906471165794	[15,12]	[10,0,0]	-8	hSpCas9	negative selection	5231005
37490257	37490279	21	+	27760321	HT29	viability after 13 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.35114374990641106	[263,205]	[155,460,421]	4	hSpCas9	negative selection	5231006
37472799	37472821	21	-	27760321	HT29	viability after 10 days	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.5660416748653478	[588,459]	[755,1175,981]	7	hSpCas9	negative selection	5314465
37480683	37480705	21	+	27760321	HT29	viability after 10 days	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.0901153332840936	[73,57]	[33,90,106]	-1	hSpCas9	negative selection	5314466
37486482	37486504	21	+	27760321	HT29	viability after 10 days	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	0.2847219254460318	[279,218]	[374,370,391]	4	hSpCas9	negative selection	5314467
37490188	37490210	21	-	27760321	HT29	viability after 10 days	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-0.9585093683976922	[15,12]	[24,1,0]	-7	hSpCas9	negative selection	5314468
37490257	37490279	21	+	27760321	HT29	viability after 10 days	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	0.880390585599267	[263,205]	[511,546,560]	9	hSpCas9	negative selection	5314469
37472799	37472821	21	-	27760321	MOLM13	viability	ACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.9063948887301255	[683,588]	[513,804]	6	hSpCas9	negative selection	5397928
37480683	37480705	21	+	27760321	MOLM13	viability	GACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.2739596402965945	[106,73]	[6,106]	1	hSpCas9	negative selection	5397929
37486482	37486504	21	+	27760321	MOLM13	viability	GATCGTGTGGAGCAAGAATGGG	DYRK1A	ENSG00000157540	-3.2118221542416516	[308,279]	[18,16]	-9	hSpCas9	negative selection	5397930
37490188	37490210	21	-	27760321	MOLM13	viability	ATGGTTTCGAAACATAAAGTGG	DYRK1A	ENSG00000157540	-2.8555288098404485	[8,15]	[0,0]	-8	hSpCas9	negative selection	5397931
37490257	37490279	21	+	27760321	MOLM13	viability	GAGAAACACCAATTTCCGAGGG	DYRK1A	ENSG00000157540	-0.17202839886167043	[317,263]	[163,128]	-1	hSpCas9	negative selection	5397932
37420468	37420491	21	+	27661255	K562	viability	GATAAATAGCAGTTAGTGGGGGG	DYRK1A	ENSG00000157540	0.08567749926617166	[812,966]	[892,631]	3	dCas9-KRAB	negative selection	5476341
37420788	37420811	21	+	27661255	K562	viability	GGATATTATACCCATACATACGG	DYRK1A	ENSG00000157540	0.11690451829587489	[766,878]	[769,660]	4	dCas9-KRAB	negative selection	5476342
37480676	37480699	21	-	27260156	BXPC3	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.052028224652346244	[968]	[904,942,1126,1269]	1	hSpCas9	negative selection	5540420
37486469	37486492	21	+	27260156	BXPC3	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.11016401594575453	[337]	[372,333,297,291]	-3	hSpCas9	negative selection	5540421
37472859	37472882	21	+	27260156	BXPC3	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.4146229037955687	[272]	[421,475,302,295]	8	hSpCas9	negative selection	5540422
37472866	37472889	21	-	27260156	BXPC3	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.3121964507699925	[417]	[581,455,507,631]	6	hSpCas9	negative selection	5604686
37480682	37480705	21	+	27260156	BXPC3	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.17482368691020467	[163]	[138,164,102,205]	-4	hSpCas9	negative selection	5604687
37486593	37486616	21	+	27260156	BXPC3	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.030148232228116523	[672]	[638,584,887,649]	0	hSpCas9	negative selection	5604688
37480676	37480699	21	-	27260156	A673	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.07454981774580383	[968]	[1112,1129,1084,1088]	-2	hSpCas9	negative selection	5661671
37486469	37486492	21	+	27260156	A673	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	0.05745193030787177	[337]	[379,348,423,538]	1	hSpCas9	negative selection	5661672
37472859	37472882	21	+	27260156	A673	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.11775454815864328	[272]	[439,329,333,326]	3	hSpCas9	negative selection	5661673
37472866	37472889	21	-	27260156	A673	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.2204054057584893	[417]	[543,575,612,600]	5	hSpCas9	negative selection	5725937
37480682	37480705	21	+	27260156	A673	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.01774233282156179	[163]	[179,160,188,249]	0	hSpCas9	negative selection	5725938
37486593	37486616	21	+	27260156	A673	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.05521642649346303	[672]	[790,659,899,760]	-1	hSpCas9	negative selection	5725939
37480676	37480699	21	-	27260156	A375	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.18440823327835654	[968]	[965,856,1173,966]	-3	hSpCas9	negative selection	5782922
37486469	37486492	21	+	27260156	A375	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-1.1648879411942201	[337]	[174,235,180,125]	-8	hSpCas9	negative selection	5782923
37472859	37472882	21	+	27260156	A375	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.570292502847399	[272]	[561,660,372,338]	8	hSpCas9	negative selection	5782924
37472866	37472889	21	-	27260156	A375	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.30095516655806726	[417]	[710,777,505,451]	4	hSpCas9	negative selection	5847188
37480682	37480705	21	+	27260156	A375	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.09086756053830469	[163]	[312,93,256,143]	1	hSpCas9	negative selection	5847189
37486593	37486616	21	+	27260156	A375	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.37239821714355226	[672]	[758,549,607,513]	-5	hSpCas9	negative selection	5847190
37480676	37480699	21	-	27260156	COLO741	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.35634093195675	[968]	[877,1006,1003]	-6	hSpCas9	negative selection	5904173
37486469	37486492	21	+	27260156	COLO741	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.5024260570812026	[337]	[327,396,198]	-8	hSpCas9	negative selection	5904174
37472859	37472882	21	+	27260156	COLO741	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.25463208761060374	[272]	[563,352,347]	5	hSpCas9	negative selection	5904175
37472866	37472889	21	-	27260156	COLO741	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.36106214500163314	[417]	[559,619,852]	7	hSpCas9	negative selection	5968439
37480682	37480705	21	+	27260156	COLO741	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.6433258505003412	[163]	[155,141,107]	-8	hSpCas9	negative selection	5968440
37486593	37486616	21	+	27260156	COLO741	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.5623558575485217	[672]	[537,607,594]	-8	hSpCas9	negative selection	5968441
37480676	37480699	21	-	27260156	CAL120	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.161509858930587	[968]	[987,1304,929]	-2	hSpCas9	negative selection	6025424
37486469	37486492	21	+	27260156	CAL120	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.7320905416617555	[337]	[425,187,172]	-8	hSpCas9	negative selection	6025425
37472859	37472882	21	+	27260156	CAL120	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.5530388883626396	[272]	[799,440,302]	7	hSpCas9	negative selection	6025426
37472866	37472889	21	-	27260156	CAL120	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.0628731865905222	[417]	[688,549,414]	0	hSpCas9	negative selection	6089690
37480682	37480705	21	+	27260156	CAL120	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.1764969353280943	[163]	[247,133,169]	-3	hSpCas9	negative selection	6089691
37486593	37486616	21	+	27260156	CAL120	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.07634406411974276	[672]	[733,927,712]	-1	hSpCas9	negative selection	6089692
37480676	37480699	21	-	27260156	CADOES1	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.5233372583711983	[968]	[612,554,636,705]	-7	hSpCas9	negative selection	6146675
37486469	37486492	21	+	27260156	CADOES1	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.6512630820274096	[337]	[135,261,200,201]	-8	hSpCas9	negative selection	6146676
37472859	37472882	21	+	27260156	CADOES1	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.05000236160828564	[272]	[299,228,240,281]	0	hSpCas9	negative selection	6146677
37472866	37472889	21	-	27260156	CADOES1	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.4864516018196462	[417]	[256,295,280,275]	-7	hSpCas9	negative selection	6210941
37480682	37480705	21	+	27260156	CADOES1	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.3990213971895811	[163]	[222,71,85,79]	-6	hSpCas9	negative selection	6210942
37486593	37486616	21	+	27260156	CADOES1	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.7588655930917518	[672]	[444,430,298,301]	-8	hSpCas9	negative selection	6210943
37480676	37480699	21	-	27260156	EWS502	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.323872551771636	[968]	[525,862,873,1065]	-5	hSpCas9	negative selection	6267926
37486469	37486492	21	+	27260156	EWS502	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.666455794250009	[337]	[106,292,205,312]	-8	hSpCas9	negative selection	6267927
37472859	37472882	21	+	27260156	EWS502	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.4822484834735122	[272]	[557,337,322,375]	8	hSpCas9	negative selection	6267928
37472866	37472889	21	-	27260156	EWS502	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.23656711191260948	[417]	[330,592,606,578]	4	hSpCas9	negative selection	6332192
37480682	37480705	21	+	27260156	EWS502	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.5031818254843734	[163]	[73,75,161,190]	-7	hSpCas9	negative selection	6332193
37486593	37486616	21	+	27260156	EWS502	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.4424889176164696	[672]	[511,459,514,619]	-6	hSpCas9	negative selection	6332194
37480676	37480699	21	-	27260156	EW8	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.09046322275440188	[968]	[1063,666,661,603]	-2	hSpCas9	negative selection	6389177
37486469	37486492	21	+	27260156	EW8	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.18413626679882544	[337]	[256,154,239,312]	-3	hSpCas9	negative selection	6389178
37472859	37472882	21	+	27260156	EW8	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.12332556456791322	[272]	[314,227,159,281]	2	hSpCas9	negative selection	6389179
37472866	37472889	21	-	27260156	EW8	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.2244273290202689	[417]	[392,450,329,418]	4	hSpCas9	negative selection	6453443
37480682	37480705	21	+	27260156	EW8	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.13871412648357162	[163]	[148,96,78,270]	2	hSpCas9	negative selection	6453444
37486593	37486616	21	+	27260156	EW8	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.13718572605092527	[672]	[527,529,424,514]	-3	hSpCas9	negative selection	6453445
37480676	37480699	21	-	27260156	CORL105	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.4202419877680882	[968]	[743,776,886,985]	-6	hSpCas9	negative selection	6510428
37486469	37486492	21	+	27260156	CORL105	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.924099424802049	[337]	[330,130,164,205]	-9	hSpCas9	negative selection	6510429
37472859	37472882	21	+	27260156	CORL105	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.1832996168245452	[272]	[410,377,399,269]	3	hSpCas9	negative selection	6510430
37472866	37472889	21	-	27260156	CORL105	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.3386498190976246	[417]	[373,367,439,373]	-6	hSpCas9	negative selection	6574694
37480682	37480705	21	+	27260156	CORL105	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.2644009395858409	[163]	[71,156,284,141]	-5	hSpCas9	negative selection	6574695
37486593	37486616	21	+	27260156	CORL105	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.4598368070456284	[672]	[489,340,906,606]	-7	hSpCas9	negative selection	6574696
37480676	37480699	21	-	27260156	HS294T	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.5263033568562075	[968]	[166,310,233,349]	-6	hSpCas9	negative selection	6631679
37486469	37486492	21	+	27260156	HS294T	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.4595097342104275	[337]	[78,67,111,128]	-6	hSpCas9	negative selection	6631680
37472859	37472882	21	+	27260156	HS294T	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.08570665062881977	[272]	[80,122,135,109]	1	hSpCas9	negative selection	6631681
37472866	37472889	21	-	27260156	HS294T	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.08097973015443333	[417]	[157,199,141,185]	1	hSpCas9	negative selection	6695945
37480682	37480705	21	+	27260156	HS294T	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.324442627893607	[163]	[45,42,63,49]	-4	hSpCas9	negative selection	6695946
37486593	37486616	21	+	27260156	HS294T	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.14049772650533005	[672]	[246,271,211,204]	-2	hSpCas9	negative selection	6695947
37480676	37480699	21	-	27260156	HCC44	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.42293637195421596	[968]	[988,721,856,733]	-6	hSpCas9	negative selection	6752930
37486469	37486492	21	+	27260156	HCC44	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-1.5350793296679148	[337]	[108,175,75,146]	-9	hSpCas9	negative selection	6752931
37472859	37472882	21	+	27260156	HCC44	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.045902701948341895	[272]	[272,296,382,328]	0	hSpCas9	negative selection	6752932
37472866	37472889	21	-	27260156	HCC44	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.6970710909829536	[417]	[315,233,300,323]	-7	hSpCas9	negative selection	6817196
37480682	37480705	21	+	27260156	HCC44	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.4486149331510121	[163]	[245,64,98,145]	-6	hSpCas9	negative selection	6817197
37486593	37486616	21	+	27260156	HCC44	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-1.0904637949500262	[672]	[475,238,493,271]	-8	hSpCas9	negative selection	6817198
37480676	37480699	21	-	27260156	G402	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.27950805985166105	[968]	[1564,1272,1209,1683]	3	hSpCas9	negative selection	6874181
37486469	37486492	21	+	27260156	G402	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	0.35126966796521486	[337]	[586,432,223,845]	4	hSpCas9	negative selection	6874182
37472859	37472882	21	+	27260156	G402	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.9817892076500853	[272]	[1035,728,631,307]	9	hSpCas9	negative selection	6874183
37472866	37472889	21	-	27260156	G402	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.29855890683370456	[417]	[864,633,488,556]	4	hSpCas9	negative selection	6938447
37480682	37480705	21	+	27260156	G402	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.6647069556768406	[163]	[42,202,126,123]	-7	hSpCas9	negative selection	6938448
37486593	37486616	21	+	27260156	G402	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.5820500488937496	[672]	[778,714,465,287]	-6	hSpCas9	negative selection	6938449
37480676	37480699	21	-	27260156	L33	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.3570414712594804	[968]	[725,337,410,820]	-7	hSpCas9	negative selection	6995432
37486469	37486492	21	+	27260156	L33	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.6674392080079036	[337]	[231,103,123,167]	-9	hSpCas9	negative selection	6995433
37472859	37472882	21	+	27260156	L33	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.32819356740208516	[272]	[388,106,239,337]	7	hSpCas9	negative selection	6995434
37472866	37472889	21	-	27260156	L33	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.034147590111265363	[417]	[469,162,265,340]	-1	hSpCas9	negative selection	7059698
37480682	37480705	21	+	27260156	L33	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.4177843651331128	[163]	[128,28,64,186]	-7	hSpCas9	negative selection	7059699
37486593	37486616	21	+	27260156	L33	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.22919619100326594	[672]	[616,181,376,633]	-5	hSpCas9	negative selection	7059700
37480676	37480699	21	-	27260156	K562	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.03419622733735883	[968]	[818,1130,568,848]	0	hSpCas9	negative selection	7116683
37486469	37486492	21	+	27260156	K562	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.7011135965281333	[337]	[152,57,143,352]	-7	hSpCas9	negative selection	7116684
37472859	37472882	21	+	27260156	K562	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.1891309178672903	[272]	[323,125,470,188]	2	hSpCas9	negative selection	7116685
37472866	37472889	21	-	27260156	K562	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.9249055615251442	[417]	[288,181,199,124]	-8	hSpCas9	negative selection	7180949
37480682	37480705	21	+	27260156	K562	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.08816146476025488	[163]	[33,244,178,154]	1	hSpCas9	negative selection	7180950
37486593	37486616	21	+	27260156	K562	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.49007794070907607	[672]	[747,588,300,130]	-5	hSpCas9	negative selection	7180951
37480676	37480699	21	-	27260156	HT29	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.35763196076304926	[968]	[1155,921,790,830]	-6	hSpCas9	negative selection	7237934
37486469	37486492	21	+	27260156	HT29	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.548695626220259	[337]	[269,256,340,253]	-7	hSpCas9	negative selection	7237935
37472859	37472882	21	+	27260156	HT29	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.29260384256409794	[272]	[364,476,378,404]	6	hSpCas9	negative selection	7237936
37472866	37472889	21	-	27260156	HT29	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.3084919050680974	[417]	[475,355,354,446]	-5	hSpCas9	negative selection	7302200
37480682	37480705	21	+	27260156	HT29	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.3184571945099919	[163]	[130,168,186,150]	-6	hSpCas9	negative selection	7302201
37486593	37486616	21	+	27260156	HT29	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.4522914763856466	[672]	[658,567,568,593]	-7	hSpCas9	negative selection	7302202
37480676	37480699	21	-	27260156	MHHES1	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.11656320217954186	[968]	[1190,1147,936,809]	-2	hSpCas9	negative selection	7359185
37486469	37486492	21	+	27260156	MHHES1	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	0.02170485766255631	[337]	[386,572,351,270]	0	hSpCas9	negative selection	7359186
37472859	37472882	21	+	27260156	MHHES1	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.531110420120809	[272]	[503,659,371,294]	8	hSpCas9	negative selection	7359187
37472866	37472889	21	-	27260156	MHHES1	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.07718980349257988	[417]	[682,422,465,432]	1	hSpCas9	negative selection	7423451
37480682	37480705	21	+	27260156	MHHES1	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.25806562859669535	[163]	[174,107,163,162]	-5	hSpCas9	negative selection	7423452
37486593	37486616	21	+	27260156	MHHES1	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	0.258295590541729	[672]	[1430,1032,749,550]	5	hSpCas9	negative selection	7423453
37480676	37480699	21	-	27260156	MEWO	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.46907039695533215	[968]	[662,694,607]	-7	hSpCas9	negative selection	7480436
37486469	37486492	21	+	27260156	MEWO	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-1.3703666550910292	[337]	[121,90,153]	-9	hSpCas9	negative selection	7480437
37472859	37472882	21	+	27260156	MEWO	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	-0.041618304725776434	[272]	[281,235,232]	-1	hSpCas9	negative selection	7480438
37472866	37472889	21	-	27260156	MEWO	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.09803581477921636	[417]	[292,368,419]	-2	hSpCas9	negative selection	7544702
37480682	37480705	21	+	27260156	MEWO	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.38966726904568616	[163]	[191,81,91]	-7	hSpCas9	negative selection	7544703
37486593	37486616	21	+	27260156	MEWO	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.7885402930452636	[672]	[448,328,331]	-9	hSpCas9	negative selection	7544704
37480676	37480699	21	-	27260156	LNCAPCLONEFGC	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.49332181018752586	[968]	[592,688,649,561]	-6	hSpCas9	negative selection	7601687
37486469	37486492	21	+	27260156	LNCAPCLONEFGC	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.8407752664542826	[337]	[120,178,196,190]	-8	hSpCas9	negative selection	7601688
37472859	37472882	21	+	27260156	LNCAPCLONEFGC	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.4769222669127212	[272]	[284,284,427,395]	7	hSpCas9	negative selection	7601689
37472866	37472889	21	-	27260156	LNCAPCLONEFGC	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.026624482719000447	[417]	[445,381,448,273]	0	hSpCas9	negative selection	7665953
37480682	37480705	21	+	27260156	LNCAPCLONEFGC	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.3001743153648413	[163]	[157,90,101,129]	-5	hSpCas9	negative selection	7665954
37486593	37486616	21	+	27260156	LNCAPCLONEFGC	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.8262287862218942	[672]	[425,357,285,293]	-8	hSpCas9	negative selection	7665955
37480676	37480699	21	-	27260156	PANC0327	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.251088197862132	[968]	[990,696,569,659]	-4	hSpCas9	negative selection	7722938
37486469	37486492	21	+	27260156	PANC0327	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.3379609362285343	[337]	[145,77,229,508]	-5	hSpCas9	negative selection	7722939
37472859	37472882	21	+	27260156	PANC0327	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.48175749811051577	[272]	[483,224,301,369]	7	hSpCas9	negative selection	7722940
37472866	37472889	21	-	27260156	PANC0327	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.26749442218605224	[417]	[235,308,417,264]	-4	hSpCas9	negative selection	7787204
37480682	37480705	21	+	27260156	PANC0327	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.2198948196384356	[163]	[89,192,148,236]	3	hSpCas9	negative selection	7787205
37486593	37486616	21	+	27260156	PANC0327	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.6081460756012659	[672]	[366,435,399,357]	-7	hSpCas9	negative selection	7787206
37480676	37480699	21	-	27260156	NCIH2009	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.30160547500918533	[968]	[740,1252,1225]	-4	hSpCas9	negative selection	7844189
37486469	37486492	21	+	27260156	NCIH2009	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.4249557304280748	[337]	[380,320,358]	-5	hSpCas9	negative selection	7844190
37472859	37472882	21	+	27260156	NCIH2009	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.18286288058507083	[272]	[466,371,466]	2	hSpCas9	negative selection	7844191
37472866	37472889	21	-	27260156	NCIH2009	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.2808561311843683	[417]	[730,522,880]	4	hSpCas9	negative selection	7908455
37480682	37480705	21	+	27260156	NCIH2009	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.10617169557921535	[163]	[158,246,220]	-1	hSpCas9	negative selection	7908456
37486593	37486616	21	+	27260156	NCIH2009	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.6923307273910001	[672]	[605,607,534]	-7	hSpCas9	negative selection	7908457
37480676	37480699	21	-	27260156	NCIH1373	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.07408722509826582	[968]	[1462,975,1402,200]	0	hSpCas9	negative selection	7965440
37486469	37486492	21	+	27260156	NCIH1373	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.8374063913036925	[337]	[112,208,196,83]	-7	hSpCas9	negative selection	7965441
37472859	37472882	21	+	27260156	NCIH1373	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.596242644167705	[272]	[872,225,561,68]	6	hSpCas9	negative selection	7965442
37472866	37472889	21	-	27260156	NCIH1373	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.5195360440277125	[417]	[839,459,637,210]	5	hSpCas9	negative selection	8029706
37480682	37480705	21	+	27260156	NCIH1373	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.6070973764332588	[163]	[99,100,118,42]	-6	hSpCas9	negative selection	8029707
37486593	37486616	21	+	27260156	NCIH1373	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.5183812553222689	[672]	[295,577,659,137]	-5	hSpCas9	negative selection	8029708
37480676	37480699	21	-	27260156	PATU8902	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.24220999490517814	[968]	[2278,1854,962,1408]	2	hSpCas9	negative selection	8086691
37486469	37486492	21	+	27260156	PATU8902	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	0.07391938423948768	[337]	[677,309,551,409]	0	hSpCas9	negative selection	8086692
37472859	37472882	21	+	27260156	PATU8902	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.5261644637611507	[272]	[566,811,431,385]	5	hSpCas9	negative selection	8086693
37472866	37472889	21	-	27260156	PATU8902	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.6845836200564538	[417]	[938,1103,701,1066]	7	hSpCas9	negative selection	8150957
37480682	37480705	21	+	27260156	PATU8902	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.9733195827023139	[163]	[812,232,181,649]	9	hSpCas9	negative selection	8150958
37486593	37486616	21	+	27260156	PATU8902	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	0.4675563129077931	[672]	[1363,1889,932,1052]	5	hSpCas9	negative selection	8150959
37480676	37480699	21	-	27260156	PANC1	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.04493694714482299	[968]	[965,821,712,724]	0	hSpCas9	negative selection	8207942
37486469	37486492	21	+	27260156	PANC1	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.06308945810865041	[337]	[213,301,414,196]	-1	hSpCas9	negative selection	8207943
37472859	37472882	21	+	27260156	PANC1	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.4645984274997895	[272]	[237,594,311,218]	7	hSpCas9	negative selection	8207944
37472866	37472889	21	-	27260156	PANC1	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.39009638817569137	[417]	[414,786,400,355]	6	hSpCas9	negative selection	8272208
37480682	37480705	21	+	27260156	PANC1	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.7267557371299699	[163]	[297,462,141,93]	9	hSpCas9	negative selection	8272209
37486593	37486616	21	+	27260156	PANC1	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	0.013346177962206385	[672]	[585,799,537,463]	0	hSpCas9	negative selection	8272210
37480676	37480699	21	-	27260156	PANC0813	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.46984265586900076	[968]	[828,790,950,721]	-6	hSpCas9	negative selection	8329193
37486469	37486492	21	+	27260156	PANC0813	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.8223964947518786	[337]	[232,186,259,218]	-8	hSpCas9	negative selection	8329194
37472859	37472882	21	+	27260156	PANC0813	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.2610815515226048	[272]	[461,264,500,319]	4	hSpCas9	negative selection	8329195
37472866	37472889	21	-	27260156	PANC0813	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.5182241250155332	[417]	[343,458,254,313]	-7	hSpCas9	negative selection	8393459
37480682	37480705	21	+	27260156	PANC0813	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.9746224827950418	[163]	[120,88,136,49]	-8	hSpCas9	negative selection	8393460
37486593	37486616	21	+	27260156	PANC0813	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.8646132588407439	[672]	[597,430,349,374]	-8	hSpCas9	negative selection	8393461
37480676	37480699	21	-	27260156	RDES	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.08100119448824805	[968]	[858,981,1062,1376]	-1	hSpCas9	negative selection	8450444
37486469	37486492	21	+	27260156	RDES	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.3879338397805995	[337]	[213,308,353,325]	-6	hSpCas9	negative selection	8450445
37472859	37472882	21	+	27260156	RDES	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.5816836849073244	[272]	[450,355,493,598]	8	hSpCas9	negative selection	8450446
37472866	37472889	21	-	27260156	RDES	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.29272138970577877	[417]	[459,503,569,884]	5	hSpCas9	negative selection	8514710
37480682	37480705	21	+	27260156	RDES	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.13513774047209992	[163]	[81,123,192,333]	-2	hSpCas9	negative selection	8514711
37486593	37486616	21	+	27260156	RDES	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.11334127325445675	[672]	[358,688,901,1029]	-2	hSpCas9	negative selection	8514712
37480676	37480699	21	-	27260156	PC3	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.10429655004793281	[968]	[548,905,1526,924]	-2	hSpCas9	negative selection	8571695
37486469	37486492	21	+	27260156	PC3	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.6172134270293873	[337]	[146,226,361,205]	-8	hSpCas9	negative selection	8571696
37472859	37472882	21	+	27260156	PC3	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.48471008410548566	[272]	[213,407,775,313]	8	hSpCas9	negative selection	8571697
37472866	37472889	21	-	27260156	PC3	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.30220242058032853	[417]	[288,416,895,667]	6	hSpCas9	negative selection	8635961
37480682	37480705	21	+	27260156	PC3	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.04585086892408907	[163]	[154,172,67,179]	-1	hSpCas9	negative selection	8635962
37486593	37486616	21	+	27260156	PC3	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.5803267961061453	[672]	[357,326,1010,304]	-8	hSpCas9	negative selection	8635963
37480676	37480699	21	-	27260156	PATU8988T	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.09034433521852403	[968]	[1002,1009,1024,945]	1	hSpCas9	negative selection	8692946
37486469	37486492	21	+	27260156	PATU8988T	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	0.17998667220782605	[337]	[245,499,307,444]	3	hSpCas9	negative selection	8692947
37472859	37472882	21	+	27260156	PATU8988T	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.43050076396778125	[272]	[380,241,356,437]	7	hSpCas9	negative selection	8692948
37472866	37472889	21	-	27260156	PATU8988T	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.5041566863908209	[417]	[748,493,463,578]	8	hSpCas9	negative selection	8757212
37480682	37480705	21	+	27260156	PATU8988T	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.2228618855417983	[163]	[86,128,206,116]	-4	hSpCas9	negative selection	8757213
37486593	37486616	21	+	27260156	PATU8988T	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	0.19191649334124627	[672]	[809,625,602,938]	3	hSpCas9	negative selection	8757214
37480676	37480699	21	-	27260156	T47D	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.44988625418874306	[968]	[751,904,784,857]	-7	hSpCas9	negative selection	8814197
37486469	37486492	21	+	27260156	T47D	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.4735748549973241	[337]	[279,228,324,304]	-7	hSpCas9	negative selection	8814198
37472859	37472882	21	+	27260156	T47D	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.19312535954951549	[272]	[481,363,298,308]	4	hSpCas9	negative selection	8814199
37472866	37472889	21	-	27260156	T47D	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	-0.04594787787127505	[417]	[550,508,466,352]	-1	hSpCas9	negative selection	8878463
37480682	37480705	21	+	27260156	T47D	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.5422895920952455	[163]	[113,130,115,164]	-8	hSpCas9	negative selection	8878464
37486593	37486616	21	+	27260156	T47D	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.5132443809913098	[672]	[605,471,569,555]	-8	hSpCas9	negative selection	8878465
37480676	37480699	21	-	27260156	SU8686	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	0.06039284890200958	[968]	[1109,817,998,1099]	1	hSpCas9	negative selection	8935448
37486469	37486492	21	+	27260156	SU8686	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.08235026078887953	[337]	[328,431,251,215]	-1	hSpCas9	negative selection	8935449
37472859	37472882	21	+	27260156	SU8686	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.6735242032740247	[272]	[520,365,383,452]	9	hSpCas9	negative selection	8935450
37472866	37472889	21	-	27260156	SU8686	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.6242443622628774	[417]	[681,773,574,466]	9	hSpCas9	negative selection	8999714
37480682	37480705	21	+	27260156	SU8686	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	0.08857993021557231	[163]	[170,132,244,143]	1	hSpCas9	negative selection	8999715
37486593	37486616	21	+	27260156	SU8686	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	0.012589212929410176	[672]	[721,605,632,738]	0	hSpCas9	negative selection	8999716
37480676	37480699	21	-	27260156	SKES1	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.20201542490376956	[968]	[897,1021,717,755]	-4	hSpCas9	negative selection	9056699
37486469	37486492	21	+	27260156	SKES1	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.8801945397276366	[337]	[271,177,167,130]	-9	hSpCas9	negative selection	9056700
37472859	37472882	21	+	27260156	SKES1	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.3656927998555936	[272]	[533,389,307,214]	7	hSpCas9	negative selection	9056701
37472866	37472889	21	-	27260156	SKES1	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.201800006251729	[417]	[756,437,436,332]	4	hSpCas9	negative selection	9120965
37480682	37480705	21	+	27260156	SKES1	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.16831379019257398	[163]	[131,190,149,114]	-4	hSpCas9	negative selection	9120966
37486593	37486616	21	+	27260156	SKES1	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.7760843530291655	[672]	[503,417,350,318]	-9	hSpCas9	negative selection	9120967
37480676	37480699	21	-	27260156	TOV112D	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.2590281065813086	[968]	[790,927,856,696]	-5	hSpCas9	negative selection	9177950
37486469	37486492	21	+	27260156	TOV112D	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.6724402280035028	[337]	[267,309,124,175]	-8	hSpCas9	negative selection	9177951
37472859	37472882	21	+	27260156	TOV112D	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.6200369431400788	[272]	[342,480,528,337]	9	hSpCas9	negative selection	9177952
37472866	37472889	21	-	27260156	TOV112D	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.39318998119901594	[417]	[603,490,709,387]	7	hSpCas9	negative selection	9242216
37480682	37480705	21	+	27260156	TOV112D	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.1062229673470747	[163]	[103,243,144,135]	-2	hSpCas9	negative selection	9242217
37486593	37486616	21	+	27260156	TOV112D	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.6313052395205958	[672]	[431,582,324,435]	-8	hSpCas9	negative selection	9242218
37480676	37480699	21	-	27260156	TC71	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.23901639472363778	[968]	[1011,861,738,910]	-6	hSpCas9	negative selection	9299201
37486469	37486492	21	+	27260156	TC71	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.13622246979066943	[337]	[357,303,277,382]	-4	hSpCas9	negative selection	9299202
37472859	37472882	21	+	27260156	TC71	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.014999430572360528	[272]	[296,320,225,343]	0	hSpCas9	negative selection	9299203
37472866	37472889	21	-	27260156	TC71	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.20112562296384262	[417]	[522,496,582,450]	5	hSpCas9	negative selection	9363467
37480682	37480705	21	+	27260156	TC71	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.5718721828168611	[163]	[92,83,103,197]	-9	hSpCas9	negative selection	9363468
37486593	37486616	21	+	27260156	TC71	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.2535056165309572	[672]	[624,713,601,470]	-6	hSpCas9	negative selection	9363469
37480676	37480699	21	-	27260156	TC32	viability	TATGACTAGAATCGTCTCCCTGG	DYRK1A	ENSG00000157540	-0.1695298097442205	[968]	[773,736,922,803]	-3	hSpCas9	negative selection	9420452
37486469	37486492	21	+	27260156	TC32	viability	TGTAAAGGCATATGATCGTGTGG	DYRK1A	ENSG00000157540	-0.4907906632915554	[337]	[187,192,272,263]	-7	hSpCas9	negative selection	9420453
37472859	37472882	21	+	27260156	TC32	viability	TCAGCAACCTCTAACTAACCAGG	DYRK1A	ENSG00000157540	0.487225475302086	[272]	[323,158,701,375]	8	hSpCas9	negative selection	9420454
37472866	37472889	21	-	27260156	TC32	viability	GAACTTACCTGGTTAGTTAGAGG	DYRK1A	ENSG00000157540	0.22402296604678712	[417]	[279,419,627,551]	4	hSpCas9	negative selection	9484718
37480682	37480705	21	+	27260156	TC32	viability	AGACGATTCTAGTCATAAGAAGG	DYRK1A	ENSG00000157540	-0.1512733719199617	[163]	[113,101,231,131]	-3	hSpCas9	negative selection	9484719
37486593	37486616	21	+	27260156	TC32	viability	ACTGAAATGAAATACTACATAGG	DYRK1A	ENSG00000157540	-0.48998411502543	[672]	[368,275,799,469]	-7	hSpCas9	negative selection	9484720
37472799	37472822	21	-	27869803	HPAFII	viability after 27 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.46702829584449096	[160]	[116,116,NaN]	4	hSpCas9	negative selection	9579221
37478224	37478247	21	-	27869803	HPAFII	viability after 27 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.5282698281759769	[140]	[137,80,NaN]	4	hSpCas9	negative selection	9579222
37480652	37480675	21	+	27869803	HPAFII	viability after 27 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	0.004780086373568748	[171]	[51,122,NaN]	0	hSpCas9	negative selection	9579223
37486480	37486503	21	+	27869803	HPAFII	viability after 27 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.7041799958301191	[281]	[258,226,NaN]	6	hSpCas9	negative selection	9579224
37490257	37490280	21	+	27869803	HPAFII	viability after 27 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.3325347028323894	[123]	[176,2,NaN]	2	hSpCas9	negative selection	9579225
37496160	37496183	21	-	27869803	HPAFII	viability after 27 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.1396778949842718	[220]	[163,97,NaN]	1	hSpCas9	negative selection	9579226
37472799	37472822	21	-	27869803	HPAFII	viability after 15 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.9714453225858313	[160]	[313,354,NaN]	9	hSpCas9	negative selection	9661670
37478224	37478247	21	-	27869803	HPAFII	viability after 15 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.7821911117604801	[140]	[304,232,NaN]	8	hSpCas9	negative selection	9661671
37480652	37480675	21	+	27869803	HPAFII	viability after 15 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.43638058218489373	[171]	[180,108,NaN]	-5	hSpCas9	negative selection	9661672
37486480	37486503	21	+	27869803	HPAFII	viability after 15 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.8734657460917267	[281]	[894,343,NaN]	8	hSpCas9	negative selection	9661673
37490257	37490280	21	+	27869803	HPAFII	viability after 15 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.9350528739574082	[123]	[432,143,NaN]	8	hSpCas9	negative selection	9661674
37496160	37496183	21	-	27869803	HPAFII	viability after 15 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.014373201150209763	[220]	[347,164,NaN]	0	hSpCas9	negative selection	9661675
37472799	37472822	21	-	27869803	ASPC1	viability after 36 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	0.2214197426107809	[506]	[341,97,194]	2	hSpCas9	negative selection	9744119
37478224	37478247	21	-	27869803	ASPC1	viability after 36 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-0.33865116216107816	[379]	[81,76,141]	-3	hSpCas9	negative selection	9744120
37480652	37480675	21	+	27869803	ASPC1	viability after 36 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.6190484738540276	[555]	[84,230,70]	-6	hSpCas9	negative selection	9744121
37486480	37486503	21	+	27869803	ASPC1	viability after 36 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	0.4281148729143566	[433]	[150,263,190]	4	hSpCas9	negative selection	9744122
37490257	37490280	21	+	27869803	ASPC1	viability after 36 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.746295021688826	[468]	[112,90,90]	-6	hSpCas9	negative selection	9744123
37496160	37496183	21	-	27869803	ASPC1	viability after 36 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.5010446665315069	[476]	[224,79,70]	-5	hSpCas9	negative selection	9744124
37472799	37472822	21	-	27869803	PATU8988S	viability after 35 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-0.6491625835056116	[571]	[101,191,NaN]	-6	hSpCas9	negative selection	9826568
37478224	37478247	21	-	27869803	PATU8988S	viability after 35 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-1.5005488224681947	[424]	[57,62,NaN]	-8	hSpCas9	negative selection	9826569
37480652	37480675	21	+	27869803	PATU8988S	viability after 35 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.9211575209385147	[462]	[86,109,NaN]	-7	hSpCas9	negative selection	9826570
37486480	37486503	21	+	27869803	PATU8988S	viability after 35 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.8915618547985527	[554]	[114,125,NaN]	-7	hSpCas9	negative selection	9826571
37490257	37490280	21	+	27869803	PATU8988S	viability after 35 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.145230874747193	[384]	[57,11,NaN]	-9	hSpCas9	negative selection	9826572
37496160	37496183	21	-	27869803	PATU8988S	viability after 35 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.659667917253429	[364]	[58,33,NaN]	-8	hSpCas9	negative selection	9826573
37472799	37472822	21	-	27869803	PATU8988S	viability after 31 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-1.0716267957665542	[571]	[93,126,NaN]	-8	hSpCas9	negative selection	9909017
37478224	37478247	21	-	27869803	PATU8988S	viability after 31 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	-1.8431114662045713	[424]	[15,86,NaN]	-9	hSpCas9	negative selection	9909018
37480652	37480675	21	+	27869803	PATU8988S	viability after 31 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-1.519331133423265	[462]	[81,41,NaN]	-8	hSpCas9	negative selection	9909019
37486480	37486503	21	+	27869803	PATU8988S	viability after 31 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	-0.485806178306345	[554]	[117,208,NaN]	-5	hSpCas9	negative selection	9909020
37490257	37490280	21	+	27869803	PATU8988S	viability after 31 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.5529017856193486	[384]	[30,19,NaN]	-9	hSpCas9	negative selection	9909021
37496160	37496183	21	-	27869803	PATU8988S	viability after 31 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.039644972762843	[364]	[30,40,NaN]	-9	hSpCas9	negative selection	9909022
37472799	37472822	21	-	27869803	HPAFII	viability after 35 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-0.42136654450243083	[160]	[18,107,NaN]	-3	hSpCas9	negative selection	9991466
37478224	37478247	21	-	27869803	HPAFII	viability after 35 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.5936710554121969	[140]	[134,76,NaN]	4	hSpCas9	negative selection	9991467
37480652	37480675	21	+	27869803	HPAFII	viability after 35 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.3349081515558111	[171]	[21,121,NaN]	-2	hSpCas9	negative selection	9991468
37486480	37486503	21	+	27869803	HPAFII	viability after 35 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	1.2516262159250966	[281]	[314,367,NaN]	8	hSpCas9	negative selection	9991469
37490257	37490280	21	+	27869803	HPAFII	viability after 35 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.3095611744058956	[123]	[145,0,NaN]	2	hSpCas9	negative selection	9991470
37496160	37496183	21	-	27869803	HPAFII	viability after 35 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.32343249400003504	[220]	[87,90,NaN]	-2	hSpCas9	negative selection	9991471
37472799	37472822	21	-	27869803	HPAFII	viability after 31 days	CACTTATGTTTGGCTGGCGACGG	DYRK1A	ENSG00000157540	-0.33479470988478277	[160]	[18,128,NaN]	-2	hSpCas9	negative selection	10073915
37478224	37478247	21	-	27869803	HPAFII	viability after 31 days	AGCAGTTGCTGGGTCACGGAAGG	DYRK1A	ENSG00000157540	0.6438549345854986	[140]	[137,107,NaN]	5	hSpCas9	negative selection	10073916
37480652	37480675	21	+	27869803	HPAFII	viability after 31 days	AAAGAAGCGAAGACACCAACAGG	DYRK1A	ENSG00000157540	-0.4686245093343431	[171]	[41,99,NaN]	-3	hSpCas9	negative selection	10073917
37486480	37486503	21	+	27869803	HPAFII	viability after 31 days	ATGATCGTGTGGAGCAAGAATGG	DYRK1A	ENSG00000157540	1.26716948542544	[281]	[434,321,NaN]	8	hSpCas9	negative selection	10073918
37490257	37490280	21	+	27869803	HPAFII	viability after 31 days	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	0.7780569503615843	[123]	[204,25,NaN]	5	hSpCas9	negative selection	10073919
37496160	37496183	21	-	27869803	HPAFII	viability after 31 days	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.044421662509819104	[220]	[136,117,NaN]	0	hSpCas9	negative selection	10073920
37472728	37472751	21	-	28162770	P31FUJ	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	0.9477700412274421	[14]	[33]	9	hSpCas9	negative selection	10147428
37493102	37493125	21	-	28162770	P31FUJ	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	0.06377646145610827	[332]	[408]	0	hSpCas9	negative selection	10147429
37490257	37490280	21	+	28162770	P31FUJ	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.7549485969489376	[190]	[132]	-5	hSpCas9	negative selection	10147430
37493140	37493163	21	-	28162770	P31FUJ	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	0.03935533929459489	[577]	[697]	0	hSpCas9	negative selection	10147431
37505328	37505351	21	+	28162770	P31FUJ	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.607546997745189	[152]	[58]	-7	hSpCas9	negative selection	10147432
37472707	37472730	21	-	28162770	P31FUJ	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.40579825990885077	[351]	[547]	4	hSpCas9	negative selection	10147433
37472754	37472777	21	-	28162770	P31FUJ	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.17475491904650675	[340]	[354]	-2	hSpCas9	negative selection	10147434
37480653	37480676	21	+	28162770	P31FUJ	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	0.002081161105266016	[344]	[405]	0	hSpCas9	negative selection	10147435
37496160	37496183	21	-	28162770	P31FUJ	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.5390098411799744	[250]	[202]	-4	hSpCas9	negative selection	10147436
37505566	37505589	21	-	28162770	P31FUJ	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.2744031088811515	[386]	[375]	-3	hSpCas9	negative selection	10147437
37472728	37472751	21	-	28162770	TF1	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10316794
37493102	37493125	21	-	28162770	TF1	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[266]	1	hSpCas9	negative selection	10316795
37490257	37490280	21	+	28162770	TF1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10316796
37493140	37493163	21	-	28162770	TF1	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10316797
37505328	37505351	21	+	28162770	TF1	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10316798
37472707	37472730	21	-	28162770	TF1	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[286]	1	hSpCas9	negative selection	10316799
37472754	37472777	21	-	28162770	TF1	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10316800
37480653	37480676	21	+	28162770	TF1	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10316801
37496160	37496183	21	-	28162770	TF1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10316802
37505566	37505589	21	-	28162770	TF1	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10316803
37472728	37472751	21	-	28162770	SKM1	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10486160
37493102	37493125	21	-	28162770	SKM1	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-1.3890422907458995	[79]	[53]	-7	hSpCas9	negative selection	10486161
37490257	37490280	21	+	28162770	SKM1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.8475367901291433	[56]	[13]	-9	hSpCas9	negative selection	10486162
37493140	37493163	21	-	28162770	SKM1	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-4.74627437185876	[166]	[10]	-9	hSpCas9	negative selection	10486163
37505328	37505351	21	+	28162770	SKM1	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-3.5000736031346436	[31]	[4]	-9	hSpCas9	negative selection	10486164
37472707	37472730	21	-	28162770	SKM1	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.2490814000394772	[98]	[207]	2	hSpCas9	negative selection	10486165
37472754	37472777	21	-	28162770	SKM1	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.6615370258287594	[67]	[75]	-5	hSpCas9	negative selection	10486166
37480653	37480676	21	+	28162770	SKM1	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.4715044509378723	[79]	[50]	-7	hSpCas9	negative selection	10486167
37496160	37496183	21	-	28162770	SKM1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-3.175638652636706	[45]	[8]	-9	hSpCas9	negative selection	10486168
37505566	37505589	21	-	28162770	SKM1	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.6405548266844736	[96]	[109]	-5	hSpCas9	negative selection	10486169
37472728	37472751	21	-	28162770	SKM1	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-2.237039197300849	[7]	[2]	-8	hSpCas9	negative selection	10655526
37493102	37493125	21	-	28162770	SKM1	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-1.3890422907458995	[79]	[53]	-7	hSpCas9	negative selection	10655527
37490257	37490280	21	+	28162770	SKM1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.8475367901291433	[56]	[13]	-9	hSpCas9	negative selection	10655528
37493140	37493163	21	-	28162770	SKM1	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-4.74627437185876	[166]	[10]	-9	hSpCas9	negative selection	10655529
37505328	37505351	21	+	28162770	SKM1	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-3.5000736031346436	[31]	[4]	-9	hSpCas9	negative selection	10655530
37472707	37472730	21	-	28162770	SKM1	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.2490814000394772	[98]	[207]	2	hSpCas9	negative selection	10655531
37472754	37472777	21	-	28162770	SKM1	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.6615370258287594	[67]	[75]	-5	hSpCas9	negative selection	10655532
37480653	37480676	21	+	28162770	SKM1	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.4715044509378723	[79]	[50]	-7	hSpCas9	negative selection	10655533
37496160	37496183	21	-	28162770	SKM1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-3.175638652636706	[45]	[8]	-9	hSpCas9	negative selection	10655534
37505566	37505589	21	-	28162770	SKM1	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.6405548266844736	[96]	[109]	-5	hSpCas9	negative selection	10655535
37472728	37472751	21	-	28162770	PL21	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-2.384822886231836	[11]	[0]	-8	hSpCas9	negative selection	10824892
37493102	37493125	21	-	28162770	PL21	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.7574817832401279	[368]	[94]	-5	hSpCas9	negative selection	10824893
37490257	37490280	21	+	28162770	PL21	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.3848228862318361	[149]	[24]	-7	hSpCas9	negative selection	10824894
37493140	37493163	21	-	28162770	PL21	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-1.3386744254279466	[522]	[89]	-7	hSpCas9	negative selection	10824895
37505328	37505351	21	+	28162770	PL21	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.500300103651772	[168]	[25]	-7	hSpCas9	negative selection	10824896
37472707	37472730	21	-	28162770	PL21	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.4331167864669343	[387]	[227]	4	hSpCas9	negative selection	10824897
37472754	37472777	21	-	28162770	PL21	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	0.7662430879591604	[230]	[170]	6	hSpCas9	negative selection	10824898
37480653	37480676	21	+	28162770	PL21	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.18913478872444173	[295]	[112]	-1	hSpCas9	negative selection	10824899
37496160	37496183	21	-	28162770	PL21	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-3.214897884789524	[127]	[5]	-9	hSpCas9	negative selection	10824900
37505566	37505589	21	-	28162770	PL21	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.2877984318369715	[459]	[163]	-2	hSpCas9	negative selection	10824901
37472728	37472751	21	-	28162770	P31FUJ	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	0.9477700412274421	[14]	[33]	9	hSpCas9	negative selection	10994258
37493102	37493125	21	-	28162770	P31FUJ	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	0.06377646145610827	[332]	[408]	0	hSpCas9	negative selection	10994259
37490257	37490280	21	+	28162770	P31FUJ	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.7549485969489376	[190]	[132]	-5	hSpCas9	negative selection	10994260
37493140	37493163	21	-	28162770	P31FUJ	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	0.03935533929459489	[577]	[697]	0	hSpCas9	negative selection	10994261
37505328	37505351	21	+	28162770	P31FUJ	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.607546997745189	[152]	[58]	-7	hSpCas9	negative selection	10994262
37472707	37472730	21	-	28162770	P31FUJ	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.40579825990885077	[351]	[547]	4	hSpCas9	negative selection	10994263
37472754	37472777	21	-	28162770	P31FUJ	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.17475491904650675	[340]	[354]	-2	hSpCas9	negative selection	10994264
37480653	37480676	21	+	28162770	P31FUJ	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	0.002081161105266016	[344]	[405]	0	hSpCas9	negative selection	10994265
37496160	37496183	21	-	28162770	P31FUJ	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.5390098411799744	[250]	[202]	-4	hSpCas9	negative selection	10994266
37505566	37505589	21	-	28162770	P31FUJ	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.2744031088811515	[386]	[375]	-3	hSpCas9	negative selection	10994267
37472728	37472751	21	-	28162770	OCIAML5	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-2.0744589922004453	[13]	[5]	-8	hSpCas9	negative selection	11163624
37493102	37493125	21	-	28162770	OCIAML5	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.9222113948922745	[294]	[280]	-5	hSpCas9	negative selection	11163625
37490257	37490280	21	+	28162770	OCIAML5	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.2573230493502554	[97]	[73]	-6	hSpCas9	negative selection	11163626
37493140	37493163	21	-	28162770	OCIAML5	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-2.0532425062907493	[314]	[136]	-8	hSpCas9	negative selection	11163627
37505328	37505351	21	+	28162770	OCIAML5	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-2.009607847850477	[57]	[25]	-8	hSpCas9	negative selection	11163628
37472707	37472730	21	-	28162770	OCIAML5	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	1.145917083537498	[178]	[714]	8	hSpCas9	negative selection	11163629
37472754	37472777	21	-	28162770	OCIAML5	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	0.04448208052306246	[223]	[416]	0	hSpCas9	negative selection	11163630
37480653	37480676	21	+	28162770	OCIAML5	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	0.1852144452154626	[190]	[391]	1	hSpCas9	negative selection	11163631
37496160	37496183	21	-	28162770	OCIAML5	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	0.27594104151207455	[96]	[211]	2	hSpCas9	negative selection	11163632
37505566	37505589	21	-	28162770	OCIAML5	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	0.09878577980691516	[208]	[403]	0	hSpCas9	negative selection	11163633
37472728	37472751	21	-	28162770	EOL1	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	0.5730754010691568	[36]	[28]	5	hSpCas9	negative selection	11332990
37493102	37493125	21	-	28162770	EOL1	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.006290203922069915	[447]	[234]	0	hSpCas9	negative selection	11332991
37490257	37490280	21	+	28162770	EOL1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.5449375117306858	[287]	[51]	-7	hSpCas9	negative selection	11332992
37493140	37493163	21	-	28162770	EOL1	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-2.3987536647255214	[1050]	[104]	-8	hSpCas9	negative selection	11332993
37505328	37505351	21	+	28162770	EOL1	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.4096066256500872	[236]	[46]	-7	hSpCas9	negative selection	11332994
37472707	37472730	21	-	28162770	EOL1	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.04511634276079812	[630]	[342]	0	hSpCas9	negative selection	11332995
37472754	37472777	21	-	28162770	EOL1	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.14154141888723787	[401]	[191]	-1	hSpCas9	negative selection	11332996
37480653	37480676	21	+	28162770	EOL1	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.24155551891936944	[376]	[167]	-2	hSpCas9	negative selection	11332997
37496160	37496183	21	-	28162770	EOL1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.1885148929161016	[198]	[45]	-7	hSpCas9	negative selection	11332998
37505566	37505589	21	-	28162770	EOL1	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	0.5286190952393953	[474]	[360]	5	hSpCas9	negative selection	11332999
37472728	37472751	21	-	28162770	MOLM13	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.2101825235680588	[15]	[4]	-6	hSpCas9	negative selection	11502356
37493102	37493125	21	-	28162770	MOLM13	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-2.3130539096822296	[865]	[125]	-8	hSpCas9	negative selection	11502357
37490257	37490280	21	+	28162770	MOLM13	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.5279589751849538	[346]	[86]	-6	hSpCas9	negative selection	11502358
37493140	37493163	21	-	28162770	MOLM13	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-3.1455758657651396	[868]	[70]	-8	hSpCas9	negative selection	11502359
37505328	37505351	21	+	28162770	MOLM13	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-1.5509696457067368	[153]	[37]	-6	hSpCas9	negative selection	11502360
37472707	37472730	21	-	28162770	MOLM13	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	1.3261806225514634	[480]	[871]	8	hSpCas9	negative selection	11502361
37472754	37472777	21	-	28162770	MOLM13	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.30855426398533703	[530]	[309]	-2	hSpCas9	negative selection	11502362
37480653	37480676	21	+	28162770	MOLM13	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.5380112198951053	[489]	[121]	-6	hSpCas9	negative selection	11502363
37496160	37496183	21	-	28162770	MOLM13	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-1.877122326455825	[314]	[61]	-7	hSpCas9	negative selection	11502364
37505566	37505589	21	-	28162770	MOLM13	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.5110928371863381	[476]	[241]	-3	hSpCas9	negative selection	11502365
37472728	37472751	21	-	28162770	HEL	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.6791892628870055	[19]	[3]	-7	hSpCas9	negative selection	11671722
37493102	37493125	21	-	28162770	HEL	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-2.6432323851105957	[633]	[64]	-8	hSpCas9	negative selection	11671723
37490257	37490280	21	+	28162770	HEL	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.3039316655935163	[238]	[30]	-8	hSpCas9	negative selection	11671724
37493140	37493163	21	-	28162770	HEL	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-4.088444409571843	[663]	[24]	-9	hSpCas9	negative selection	11671725
37505328	37505351	21	+	28162770	HEL	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-5.198563421980585	[171]	[2]	-9	hSpCas9	negative selection	11671726
37472707	37472730	21	-	28162770	HEL	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-1.7427543916644714	[579]	[110]	-7	hSpCas9	negative selection	11671727
37472754	37472777	21	-	28162770	HEL	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-1.0913951713826866	[508]	[152]	-6	hSpCas9	negative selection	11671728
37480653	37480676	21	+	28162770	HEL	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-2.262103934959303	[351]	[46]	-8	hSpCas9	negative selection	11671729
37496160	37496183	21	-	28162770	HEL	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.137774477838606	[212]	[30]	-8	hSpCas9	negative selection	11671730
37505566	37505589	21	-	28162770	HEL	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-1.2197576442497082	[439]	[120]	-6	hSpCas9	negative selection	11671731
37472728	37472751	21	-	28162770	MV411	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	0.5693656456701377	[7]	[9]	5	hSpCas9	negative selection	11841088
37493102	37493125	21	-	28162770	MV411	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.6393518387692336	[293]	[158]	-4	hSpCas9	negative selection	11841089
37490257	37490280	21	+	28162770	MV411	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.18065610132151483	[147]	[109]	-1	hSpCas9	negative selection	11841090
37493140	37493163	21	-	28162770	MV411	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-1.5361230709351552	[450]	[130]	-7	hSpCas9	negative selection	11841091
37505328	37505351	21	+	28162770	MV411	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-2.023864471034619	[139]	[28]	-8	hSpCas9	negative selection	11841092
37472707	37472730	21	-	28162770	MV411	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.11776693833799246	[348]	[318]	1	hSpCas9	negative selection	11841093
37472754	37472777	21	-	28162770	MV411	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.10657051509850904	[215]	[168]	-1	hSpCas9	negative selection	11841094
37480653	37480676	21	+	28162770	MV411	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-0.964307626354164	[314]	[135]	-6	hSpCas9	negative selection	11841095
37496160	37496183	21	-	28162770	MV411	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.9288852218576876	[112]	[49]	-6	hSpCas9	negative selection	11841096
37505566	37505589	21	-	28162770	MV411	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	0.3405469551742567	[269]	[287]	3	hSpCas9	negative selection	11841097
37472728	37472751	21	-	28162770	MONOMAC1	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.897476565200646	[12]	[3]	-8	hSpCas9	negative selection	12010454
37493102	37493125	21	-	28162770	MONOMAC1	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-1.3482009203932044	[190]	[85]	-7	hSpCas9	negative selection	12010455
37490257	37490280	21	+	28162770	MONOMAC1	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-0.9092345360768177	[76]	[46]	-6	hSpCas9	negative selection	12010456
37493140	37493163	21	-	28162770	MONOMAC1	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-2.84701913963112	[294]	[46]	-9	hSpCas9	negative selection	12010457
37505328	37505351	21	+	28162770	MONOMAC1	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-0.06871275008401445	[85]	[93]	0	hSpCas9	negative selection	12010458
37472707	37472730	21	-	28162770	MONOMAC1	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-0.1472838118624542	[227]	[235]	-1	hSpCas9	negative selection	12010459
37472754	37472777	21	-	28162770	MONOMAC1	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-1.1970368470595536	[205]	[102]	-7	hSpCas9	negative selection	12010460
37480653	37480676	21	+	28162770	MONOMAC1	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.24716032648539	[204]	[98]	-7	hSpCas9	negative selection	12010461
37496160	37496183	21	-	28162770	MONOMAC1	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.0609752974835254	[90]	[24]	-9	hSpCas9	negative selection	12010462
37505566	37505589	21	-	28162770	MONOMAC1	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.18367846420453482	[214]	[216]	-2	hSpCas9	negative selection	12010463
37472728	37472751	21	-	28162770	OCIAML2	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	1.2298098928989307	[0]	[12]	9	hSpCas9	negative selection	12179820
37493102	37493125	21	-	28162770	OCIAML2	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-1.4294071625156484	[68]	[141]	-7	hSpCas9	negative selection	12179821
37490257	37490280	21	+	28162770	OCIAML2	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-1.9251956887076425	[36]	[53]	-8	hSpCas9	negative selection	12179822
37493140	37493163	21	-	28162770	OCIAML2	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-5.533639622767962	[116]	[13]	-9	hSpCas9	negative selection	12179823
37505328	37505351	21	+	28162770	OCIAML2	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-3.824266779856862	[22]	[8]	-9	hSpCas9	negative selection	12179824
37472707	37472730	21	-	28162770	OCIAML2	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	0.5052699249573447	[82]	[652]	5	hSpCas9	negative selection	12179825
37472754	37472777	21	-	28162770	OCIAML2	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	-0.14215888448802697	[43]	[220]	-1	hSpCas9	negative selection	12179826
37480653	37480676	21	+	28162770	OCIAML2	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.3860963150304935	[57]	[122]	-7	hSpCas9	negative selection	12179827
37496160	37496183	21	-	28162770	OCIAML2	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-2.0160639617766805	[26]	[36]	-8	hSpCas9	negative selection	12179828
37505566	37505589	21	-	28162770	OCIAML2	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-0.31220046263767826	[55]	[249]	-3	hSpCas9	negative selection	12179829
37472728	37472751	21	-	28162770	OCIAML3	viability	GCAGCATGGAATGAAAATGACGG	DYRK1A	ENSG00000157540	-1.5940076403241634	[7]	[7]	-8	hSpCas9	negative selection	12349186
37493102	37493125	21	-	28162770	OCIAML3	viability	TTCAACCAAAATACACCCGAGGG	DYRK1A	ENSG00000157540	-0.17079620959961916	[87]	[235]	-1	hSpCas9	negative selection	12349187
37490257	37490280	21	+	28162770	OCIAML3	viability	GAGAAACACCAATTTCCGAGGGG	DYRK1A	ENSG00000157540	-2.795641501493814	[45]	[19]	-9	hSpCas9	negative selection	12349188
37493140	37493163	21	-	28162770	OCIAML3	viability	TCATTGGCACCACTGAACAGAGG	DYRK1A	ENSG00000157540	-2.3125947051755142	[129]	[78]	-9	hSpCas9	negative selection	12349189
37505328	37505351	21	+	28162770	OCIAML3	viability	GTGGAAACAGGAGGACCTGGTGG	DYRK1A	ENSG00000157540	-2.390474246239031	[32]	[18]	-9	hSpCas9	negative selection	12349190
37472707	37472730	21	-	28162770	OCIAML3	viability	GGTGCAAGCCGAACAGATGAAGG	DYRK1A	ENSG00000157540	-0.7831637321866793	[117]	[206]	-5	hSpCas9	negative selection	12349191
37472754	37472777	21	-	28162770	OCIAML3	viability	GCATCTGTCCAGCCATCTGAAGG	DYRK1A	ENSG00000157540	0.13534476973216772	[56]	[188]	1	hSpCas9	negative selection	12349192
37480653	37480676	21	+	28162770	OCIAML3	viability	AAGAAGCGAAGACACCAACAGGG	DYRK1A	ENSG00000157540	-1.4729922393627974	[79]	[86]	-7	hSpCas9	negative selection	12349193
37496160	37496183	21	-	28162770	OCIAML3	viability	GCTTGGTCAAGAATATGAGCAGG	DYRK1A	ENSG00000157540	-0.5787408836708527	[46]	[94]	-4	hSpCas9	negative selection	12349194
37505566	37505589	21	-	28162770	OCIAML3	viability	TGAGCTTGACGATGTACTGGAGG	DYRK1A	ENSG00000157540	-1.0472644618334972	[101]	[148]	-6	hSpCas9	negative selection	12349195