Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1892
• Symbol: ECHS1
• Description: enoyl-CoA hydratase, short chain 1

DataSource: http://genomecrispr.dkfz.de/#!/results/ECHS1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
133370704	133370727	10	-	26472758	Jiyoye	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.7303281422440616	[65]	[29]	-5	hSpCas9	negative selection	48042
133369942	133369965	10	-	26472758	Jiyoye	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-4.985142041272887	[209]	[4]	-9	hSpCas9	negative selection	48043
133373307	133373330	10	+	26472758	Jiyoye	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.7511297827232345	[77]	[98]	5	hSpCas9	negative selection	48044
133370611	133370634	10	-	26472758	Jiyoye	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.6020431485235053	[156]	[77]	-4	hSpCas9	negative selection	48045
133370577	133370600	10	-	26472758	Jiyoye	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.06855804946052446	[88]	[63]	0	hSpCas9	negative selection	48046
133366934	133366957	10	-	26472758	Jiyoye	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	1.5274696152235854	[22]	[49]	8	hSpCas9	negative selection	48047
133373262	133373285	10	+	26472758	Jiyoye	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	0.4244533729377089	[82]	[83]	3	hSpCas9	negative selection	48048
133370677	133370700	10	-	26472758	Jiyoye	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	0.2816444994220146	[167]	[153]	2	hSpCas9	negative selection	48049
133370665	133370688	10	+	26472758	Jiyoye	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.16959655635474946	[190]	[161]	1	hSpCas9	negative selection	48050
133370546	133370569	10	+	26472758	Jiyoye	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.9106079967304312	[90]	[128]	6	hSpCas9	negative selection	48051
133370704	133370727	10	-	26472758	KBM7	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.7893193367751907	[141,101]	[60,130]	8	hSpCas9	negative selection	239160
133369942	133369965	10	-	26472758	KBM7	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-2.9463165317666773	[934,720]	[38,59]	-9	hSpCas9	negative selection	239161
133373307	133373330	10	+	26472758	KBM7	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.24575988159617435	[345,315]	[201,168]	2	hSpCas9	negative selection	239162
133370611	133370634	10	-	26472758	KBM7	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.30459309355052344	[707,350]	[202,188]	-3	hSpCas9	negative selection	239163
133370577	133370600	10	-	26472758	KBM7	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.20255370547451923	[353,203]	[193,105]	2	hSpCas9	negative selection	239164
133366934	133366957	10	-	26472758	KBM7	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.379826740894458	[240,313]	[99,103]	-3	hSpCas9	negative selection	239165
133373262	133373285	10	+	26472758	KBM7	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	0.3904383099054535	[281,297]	[196,164]	4	hSpCas9	negative selection	239166
133370677	133370700	10	-	26472758	KBM7	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	0.3472616625186884	[795,567]	[403,401]	3	hSpCas9	negative selection	239167
133370665	133370688	10	+	26472758	KBM7	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.2688304622065162	[741,807]	[450,435]	3	hSpCas9	negative selection	239168
133370546	133370569	10	+	26472758	KBM7	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.5222502046201891	[829,688]	[434,577]	5	hSpCas9	negative selection	239169
133370704	133370727	10	-	26472758	Raji	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.8305433300147753	[62]	[25]	7	hSpCas9	negative selection	430278
133369942	133369965	10	-	26472758	Raji	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-1.8148143130227674	[378]	[24]	-8	hSpCas9	negative selection	430279
133373307	133373330	10	+	26472758	Raji	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.9403695960747688	[214]	[25]	-6	hSpCas9	negative selection	430280
133370611	133370634	10	-	26472758	Raji	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	0.37304341061421664	[182]	[54]	3	hSpCas9	negative selection	430281
133370577	133370600	10	-	26472758	Raji	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.9347441492342512	[132]	[58]	8	hSpCas9	negative selection	430282
133366934	133366957	10	-	26472758	Raji	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.26607486015384474	[113]	[21]	-2	hSpCas9	negative selection	430283
133373262	133373285	10	+	26472758	Raji	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-0.9537279789297878	[216]	[25]	-6	hSpCas9	negative selection	430284
133370677	133370700	10	-	26472758	Raji	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	0.45811200211379144	[366]	[116]	4	hSpCas9	negative selection	430285
133370665	133370688	10	+	26472758	Raji	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-1.6896294424625458	[416]	[29]	-8	hSpCas9	negative selection	430286
133370546	133370569	10	+	26472758	Raji	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.966027686128058	[224]	[101]	8	hSpCas9	negative selection	430287
133370704	133370727	10	-	26472758	K562	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	1.657556694029809	[94]	[252]	9	hSpCas9	negative selection	621396
133369942	133369965	10	-	26472758	K562	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-3.9919579231057023	[621]	[32]	-9	hSpCas9	negative selection	621397
133373307	133373330	10	+	26472758	K562	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.9617322643719353	[339]	[558]	7	hSpCas9	negative selection	621398
133370611	133370634	10	-	26472758	K562	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.6525929589007826	[472]	[126]	-7	hSpCas9	negative selection	621399
133370577	133370600	10	-	26472758	K562	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.0615678233518937	[224]	[181]	0	hSpCas9	negative selection	621400
133366934	133366957	10	-	26472758	K562	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.20883809384288687	[203]	[148]	-1	hSpCas9	negative selection	621401
133373262	133373285	10	+	26472758	K562	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	0.5140257874237268	[218]	[263]	4	hSpCas9	negative selection	621402
133370677	133370700	10	-	26472758	K562	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	1.1806342192967103	[473]	[906]	8	hSpCas9	negative selection	621403
133370665	133370688	10	+	26472758	K562	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-2.8965064020533133	[590]	[66]	-8	hSpCas9	negative selection	621404
133370546	133370569	10	+	26472758	K562	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.9521360945276092	[577]	[943]	7	hSpCas9	negative selection	621405
133366060	133366083	10	-	26627737	DLD1	viability	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.20587755599982804	[122]	[64,62,10]	2	hSpCas9	negative selection	774406
133366934	133366957	10	-	26627737	DLD1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.4699888334158656	[179]	[64,123,50]	5	hSpCas9	negative selection	774407
133368965	133368988	10	-	26627737	DLD1	viability	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.049820681361912644	[251]	[74,82,85]	0	hSpCas9	negative selection	774408
133369924	133369947	10	+	26627737	DLD1	viability	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.20965995400138826	[802]	[405,189,272]	2	hSpCas9	negative selection	774409
133370575	133370598	10	-	26627737	DLD1	viability	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.778828722592305	[706]	[215,81,91]	-6	hSpCas9	negative selection	774410
133373236	133373259	10	+	26627737	DLD1	viability	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.5057454939706663	[1018]	[122,296,251]	-5	hSpCas9	negative selection	774411
133366060	133366083	10	-	26627737	GBM cells	viability after 5 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.10108612511431447	[99]	[51,47]	-1	hSpCas9	negative selection	856721
133366934	133366957	10	-	26627737	GBM cells	viability after 5 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.1707184903472116	[163]	[92,104]	2	hSpCas9	negative selection	856722
133368965	133368988	10	-	26627737	GBM cells	viability after 5 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.049247193594696204	[163]	[103,65]	0	hSpCas9	negative selection	856723
133369924	133369947	10	+	26627737	GBM cells	viability after 5 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.5910521118997237	[381]	[134,136]	-7	hSpCas9	negative selection	856724
133370575	133370598	10	-	26627737	GBM cells	viability after 5 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.44381883514097303	[226]	[108,69]	-6	hSpCas9	negative selection	856725
133373236	133373259	10	+	26627737	GBM cells	viability after 5 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.3298387112302028	[340]	[132,157]	-5	hSpCas9	negative selection	856726
133366060	133366083	10	-	26627737	GBM cells	viability after 13 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.5986214002543011	[99]	[42,29]	-6	hSpCas9	negative selection	939036
133366934	133366957	10	-	26627737	GBM cells	viability after 13 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.1349442087056102	[163]	[85,76]	-2	hSpCas9	negative selection	939037
133368965	133368988	10	-	26627737	GBM cells	viability after 13 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.8248194626694851	[163]	[36,60]	-7	hSpCas9	negative selection	939038
133369924	133369947	10	+	26627737	GBM cells	viability after 13 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.43627481254200495	[381]	[161,145]	-5	hSpCas9	negative selection	939039
133370575	133370598	10	-	26627737	GBM cells	viability after 13 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.2430879330360659	[226]	[97,108]	-3	hSpCas9	negative selection	939040
133373236	133373259	10	+	26627737	GBM cells	viability after 13 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.1469949727272325	[340]	[149,180]	-2	hSpCas9	negative selection	939041
133366060	133366083	10	-	26627737	GBM cells	viability after 21 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-1.3358677478854872	[99]	[20,21]	-8	hSpCas9	negative selection	1021351
133366934	133366957	10	-	26627737	GBM cells	viability after 21 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.04902837748112576	[163]	[87,95]	0	hSpCas9	negative selection	1021352
133368965	133368988	10	-	26627737	GBM cells	viability after 21 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.010256645240750428	[163]	[100,76]	0	hSpCas9	negative selection	1021353
133369924	133369947	10	+	26627737	GBM cells	viability after 21 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.2908251535342066	[381]	[177,161]	-3	hSpCas9	negative selection	1021354
133370575	133370598	10	-	26627737	GBM cells	viability after 21 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.47635687591776793	[226]	[96,80]	-4	hSpCas9	negative selection	1021355
133373236	133373259	10	+	26627737	GBM cells	viability after 21 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.6010814369200886	[340]	[118,124]	-5	hSpCas9	negative selection	1021356
133366060	133366083	10	-	26627737	RPE1	viability after 9 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.9097586825865889	[145]	[115,46]	6	hSpCas9	negative selection	1103666
133366934	133366957	10	-	26627737	RPE1	viability after 9 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.2219721723197987	[378]	[123,72]	-1	hSpCas9	negative selection	1103667
133368965	133368988	10	-	26627737	RPE1	viability after 9 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.1288142048215295	[245]	[38,110]	-1	hSpCas9	negative selection	1103668
133369924	133369947	10	+	26627737	RPE1	viability after 9 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.0653437490049	[742]	[94,131]	-6	hSpCas9	negative selection	1103669
133370575	133370598	10	-	26627737	RPE1	viability after 9 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.9936623540493887	[969]	[93,227]	-6	hSpCas9	negative selection	1103670
133373236	133373259	10	+	26627737	RPE1	viability after 9 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.18074651641407308	[713]	[310,178]	1	hSpCas9	negative selection	1103671
133366060	133366083	10	-	26627737	RPE1	viability after 12 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.4921362847988042	[145]	[77,30]	3	hSpCas9	negative selection	1185981
133366934	133366957	10	-	26627737	RPE1	viability after 12 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.14235391782893947	[378]	[100,82]	-1	hSpCas9	negative selection	1185982
133368965	133368988	10	-	26627737	RPE1	viability after 12 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.28238457975050535	[245]	[31,77]	-2	hSpCas9	negative selection	1185983
133369924	133369947	10	+	26627737	RPE1	viability after 12 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.6010913100175792	[742]	[58,72]	-8	hSpCas9	negative selection	1185984
133370575	133370598	10	-	26627737	RPE1	viability after 12 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-1.1309117620934086	[969]	[50,190]	-7	hSpCas9	negative selection	1185985
133373236	133373259	10	+	26627737	RPE1	viability after 12 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.47455485845735024	[713]	[420,102]	3	hSpCas9	negative selection	1185986
133366060	133366083	10	-	26627737	RPE1	viability after 15 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	1.1828625766026175	[145]	[78,107]	6	hSpCas9	negative selection	1268296
133366934	133366957	10	-	26627737	RPE1	viability after 15 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.0874391262976344	[378]	[118,108]	0	hSpCas9	negative selection	1268297
133368965	133368988	10	-	26627737	RPE1	viability after 15 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.1336751889349146	[245]	[56,94]	0	hSpCas9	negative selection	1268298
133369924	133369947	10	+	26627737	RPE1	viability after 15 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.0930201153907393	[742]	[96,99]	-6	hSpCas9	negative selection	1268299
133370575	133370598	10	-	26627737	RPE1	viability after 15 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.9006195699179403	[969]	[119,172]	-5	hSpCas9	negative selection	1268300
133373236	133373259	10	+	26627737	RPE1	viability after 15 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.7219741589439109	[713]	[549,123]	4	hSpCas9	negative selection	1268301
133366060	133366083	10	-	26627737	RPE1	viability after 18 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.4408633105927384	[145]	[52,53]	3	hSpCas9	negative selection	1350611
133366934	133366957	10	-	26627737	RPE1	viability after 18 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.3311434613325175	[378]	[60,102]	-2	hSpCas9	negative selection	1350612
133368965	133368988	10	-	26627737	RPE1	viability after 18 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.12068288742897204	[245]	[91,50]	0	hSpCas9	negative selection	1350613
133369924	133369947	10	+	26627737	RPE1	viability after 18 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.432931769785096	[742]	[81,65]	-7	hSpCas9	negative selection	1350614
133370575	133370598	10	-	26627737	RPE1	viability after 18 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.7716599907776551	[969]	[60,251]	-5	hSpCas9	negative selection	1350615
133373236	133373259	10	+	26627737	RPE1	viability after 18 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.8277605032671322	[713]	[516,154]	5	hSpCas9	negative selection	1350616
133366060	133366083	10	-	26627737	HeLa	viability after 8 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.8097609185960868	[168]	[83,51,1]	-7	hSpCas9	negative selection	1432926
133366934	133366957	10	-	26627737	HeLa	viability after 8 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.30489628663550383	[202]	[88,7,117]	-3	hSpCas9	negative selection	1432927
133368965	133368988	10	-	26627737	HeLa	viability after 8 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.5998959253984506	[110]	[87,33,98]	5	hSpCas9	negative selection	1432928
133369924	133369947	10	+	26627737	HeLa	viability after 8 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.6749378425031203	[522]	[561,345,234]	6	hSpCas9	negative selection	1432929
133370575	133370598	10	-	26627737	HeLa	viability after 8 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.353081428237121	[364]	[203,233,172]	3	hSpCas9	negative selection	1432930
133373236	133373259	10	+	26627737	HeLa	viability after 8 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.11985207148903676	[611]	[178,229,424]	1	hSpCas9	negative selection	1432931
133366060	133366083	10	-	26627737	HeLa	viability after 12 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.8036004426961527	[168]	[15,80,17]	-6	hSpCas9	negative selection	1515241
133366934	133366957	10	-	26627737	HeLa	viability after 12 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.01802752574302846	[202]	[49,163,24]	0	hSpCas9	negative selection	1515242
133368965	133368988	10	-	26627737	HeLa	viability after 12 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	1.0279943102929476	[110]	[179,75,28]	7	hSpCas9	negative selection	1515243
133369924	133369947	10	+	26627737	HeLa	viability after 12 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.1437752870025375	[522]	[84,305,180]	-1	hSpCas9	negative selection	1515244
133370575	133370598	10	-	26627737	HeLa	viability after 12 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.39297460737038836	[364]	[339,87,181]	3	hSpCas9	negative selection	1515245
133373236	133373259	10	+	26627737	HeLa	viability after 12 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.2677598387703958	[611]	[230,137,559]	2	hSpCas9	negative selection	1515246
133366060	133366083	10	-	26627737	HeLa	viability after 15 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.4212277389050493	[168]	[14,198,60]	3	hSpCas9	negative selection	1597556
133366934	133366957	10	-	26627737	HeLa	viability after 15 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.5323385955538558	[202]	[28,70,72]	-5	hSpCas9	negative selection	1597557
133368965	133368988	10	-	26627737	HeLa	viability after 15 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.9514407322524144	[110]	[73,116,69]	7	hSpCas9	negative selection	1597558
133369924	133369947	10	+	26627737	HeLa	viability after 15 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.1447299479181135	[522]	[48,297,371]	1	hSpCas9	negative selection	1597559
133370575	133370598	10	-	26627737	HeLa	viability after 15 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.7094621308398342	[364]	[242,217,269]	5	hSpCas9	negative selection	1597560
133373236	133373259	10	+	26627737	HeLa	viability after 15 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.4022102390954616	[611]	[188,182,193]	-3	hSpCas9	negative selection	1597561
133366060	133366083	10	-	26627737	HeLa	viability after 18 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.4804846400927071	[168]	[10,172,60]	4	hSpCas9	negative selection	1679871
133366934	133366957	10	-	26627737	HeLa	viability after 18 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.5103109110823456	[202]	[20,58,72]	-4	hSpCas9	negative selection	1679872
133368965	133368988	10	-	26627737	HeLa	viability after 18 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	1.003496490157569	[110]	[50,102,69]	7	hSpCas9	negative selection	1679873
133369924	133369947	10	+	26627737	HeLa	viability after 18 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.17750725639505877	[522]	[35,255,371]	1	hSpCas9	negative selection	1679874
133370575	133370598	10	-	26627737	HeLa	viability after 18 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.7250889426738045	[364]	[162,186,269]	5	hSpCas9	negative selection	1679875
133373236	133373259	10	+	26627737	HeLa	viability after 18 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.35741857680377637	[611]	[137,151,193]	-3	hSpCas9	negative selection	1679876
133366060	133366083	10	-	26627737	HCT116	viability after 6 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	1.1824057846205973	[91]	[17,40]	6	hSpCas9	negative selection	1762186
133366934	133366957	10	-	26627737	HCT116	viability after 6 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.6145956378593413	[273]	[31,25]	-4	hSpCas9	negative selection	1762187
133368965	133368988	10	-	26627737	HCT116	viability after 6 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.4319204827637201	[285]	[137,17]	2	hSpCas9	negative selection	1762188
133369924	133369947	10	+	26627737	HCT116	viability after 6 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	1.4517736063134785	[1043]	[330,513]	7	hSpCas9	negative selection	1762189
133370575	133370598	10	-	26627737	HCT116	viability after 6 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	1.1257599978081152	[499]	[215,146]	6	hSpCas9	negative selection	1762190
133373236	133373259	10	+	26627737	HCT116	viability after 6 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	1.1252959551976145	[997]	[407,305]	6	hSpCas9	negative selection	1762191
133366060	133366083	10	-	26627737	HCT116	viability after 8 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.5239157812961153	[93]	[29,44,32]	-6	hSpCas9	negative selection	1844501
133366934	133366957	10	-	26627737	HCT116	viability after 8 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.51869948293943	[133]	[169,83,64]	5	hSpCas9	negative selection	1844502
133368965	133368988	10	-	26627737	HCT116	viability after 8 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.6314834097575107	[133]	[117,174,50]	6	hSpCas9	negative selection	1844503
133369924	133369947	10	+	26627737	HCT116	viability after 8 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.8504037894527966	[311]	[296,265,365]	7	hSpCas9	negative selection	1844504
133370575	133370598	10	-	26627737	HCT116	viability after 8 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.6664490583794046	[600]	[296,159,170]	-7	hSpCas9	negative selection	1844505
133373236	133373259	10	+	26627737	HCT116	viability after 8 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.02196706885404276	[448]	[126,174,446]	0	hSpCas9	negative selection	1844506
133366060	133366083	10	-	26627737	HCT116	viability after 9 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	2.321404079724249	[91]	[38,188]	9	hSpCas9	negative selection	1926816
133366934	133366957	10	-	26627737	HCT116	viability after 9 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	1.7107581694152685	[273]	[24,408]	9	hSpCas9	negative selection	1926817
133368965	133368988	10	-	26627737	HCT116	viability after 9 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.24920640415003192	[285]	[99,35]	-2	hSpCas9	negative selection	1926818
133369924	133369947	10	+	26627737	HCT116	viability after 9 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.5016734729924734	[1043]	[492,316]	3	hSpCas9	negative selection	1926819
133370575	133370598	10	-	26627737	HCT116	viability after 9 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.8560802108725223	[499]	[282,208]	6	hSpCas9	negative selection	1926820
133373236	133373259	10	+	26627737	HCT116	viability after 9 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.26109455115204727	[997]	[253,370]	2	hSpCas9	negative selection	1926821
133366060	133366083	10	-	26627737	HCT116	viability after 12 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.7786581470640259	[93]	[31,89,136]	7	hSpCas9	negative selection	2009131
133366934	133366957	10	-	26627737	HCT116	viability after 12 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.9180774694872004	[133]	[129,154,114]	7	hSpCas9	negative selection	2009132
133368965	133368988	10	-	26627737	HCT116	viability after 12 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.5825243170417903	[133]	[75,148,94]	5	hSpCas9	negative selection	2009133
133369924	133369947	10	+	26627737	HCT116	viability after 12 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.772693622130522	[311]	[270,148,417]	7	hSpCas9	negative selection	2009134
133370575	133370598	10	-	26627737	HCT116	viability after 12 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.5078109840353455	[600]	[218,194,251]	-5	hSpCas9	negative selection	2009135
133373236	133373259	10	+	26627737	HCT116	viability after 12 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.17300254166517903	[448]	[220,264,315]	1	hSpCas9	negative selection	2009136
133366060	133366083	10	-	26627737	HCT116	viability after 15 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.3058128063813852	[93]	[56,61,13]	-3	hSpCas9	negative selection	2091446
133366934	133366957	10	-	26627737	HCT116	viability after 15 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.409900650687125	[133]	[125,112,70]	4	hSpCas9	negative selection	2091447
133368965	133368988	10	-	26627737	HCT116	viability after 15 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.9197398320078453	[133]	[146,150,138]	7	hSpCas9	negative selection	2091448
133369924	133369947	10	+	26627737	HCT116	viability after 15 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.6397948762617786	[311]	[375,249,223]	6	hSpCas9	negative selection	2091449
133370575	133370598	10	-	26627737	HCT116	viability after 15 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.40707265828500083	[600]	[224,241,308]	-4	hSpCas9	negative selection	2091450
133373236	133373259	10	+	26627737	HCT116	viability after 15 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.30628326117919824	[448]	[394,350,220]	3	hSpCas9	negative selection	2091451
133366060	133366083	10	-	26627737	HCT116	viability after 18 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.7373361443113058	[93]	[128,81,12]	6	hSpCas9	negative selection	2173761
133366934	133366957	10	-	26627737	HCT116	viability after 18 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.9234400518233141	[133]	[154,131,78]	7	hSpCas9	negative selection	2173762
133368965	133368988	10	-	26627737	HCT116	viability after 18 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.8583634783638492	[133]	[160,93,97]	6	hSpCas9	negative selection	2173763
133369924	133369947	10	+	26627737	HCT116	viability after 18 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.4268927413447533	[311]	[302,35,283]	3	hSpCas9	negative selection	2173764
133370575	133370598	10	-	26627737	HCT116	viability after 18 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.7315449529516453	[600]	[180,274,56]	-6	hSpCas9	negative selection	2173765
133373236	133373259	10	+	26627737	HCT116	viability after 18 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.7511269705149441	[448]	[385,305,409]	6	hSpCas9	negative selection	2173766
133373535	133373558	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGCCCAGGGCGGGGTCCCGGG	ECHS1	ENSG00000127884	1.0290567366346641	[155,28]	[74,3]	4	dCas9-VP64	positive selection	2434639
133373491	133373514	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGAGCGGCAGCTCGGGCCTGG	ECHS1	ENSG00000127884	-0.6386141772358556	[8,66]	[2,6]	-3	dCas9-VP64	positive selection	2434640
133373517	133373540	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAAGGCCGAGGGGCGTCCCCGG	ECHS1	ENSG00000127884	-0.7513606469502134	[26,7]	[2,0]	-4	dCas9-VP64	positive selection	2434641
133373535	133373558	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGCCCAGGGCGGGGTCCCGGG	ECHS1	ENSG00000127884	-0.4001773810647622	[74,65]	[16,16]	-4	dCas9-VP64	positive selection	2529894
133373491	133373514	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGAGCGGCAGCTCGGGCCTGG	ECHS1	ENSG00000127884	0.080704896251798	[60,21]	[3,23]	0	dCas9-VP64	positive selection	2529895
133373517	133373540	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAAGGCCGAGGGGCGTCCCCGG	ECHS1	ENSG00000127884	-1.2660590250958557	[29,141]	[7,13]	-9	dCas9-VP64	positive selection	2529896
133370704	133370727	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.6474944188420986	[3,2]	[2,0]	-7	hSpCas9	positive selection	2984981
133370720	133370743	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	-0.2454062757290863	[2,3]	[2,1]	-3	hSpCas9	positive selection	2984982
133370702	133370725	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	-0.7630213348430313	[3,3]	[2,0]	-8	hSpCas9	positive selection	2984983
133370688	133370711	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	-0.17908150620892607	[4,4]	[4,1]	-3	hSpCas9	positive selection	2984984
133370704	133370727	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.26442827693458326	[3,3]	[3,0]	-4	hSpCas9	positive selection	3052839
133370720	133370743	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	-0.06959565059615175	[2,2]	[3,0]	-1	hSpCas9	positive selection	3052840
133370702	133370725	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	-0.25269872084738265	[3,3]	[2,1]	-4	hSpCas9	positive selection	3052841
133370688	133370711	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	-0.04772680951642652	[4,4]	[4,1]	0	hSpCas9	positive selection	3052842
133370632	133370655		-	24336571	A375	resistance to PLX after 7 days	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	-0.10644588478849881	[19,20]	[20,16]	-3	hSpCas9	positive selection	3111162
133373260	133373283		+	24336571	A375	resistance to PLX after 7 days	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.22379144380517735	[3,4]	[5,5]	6	hSpCas9	positive selection	3111163
133373235	133373258		+	24336571	A375	resistance to PLX after 7 days	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.14896254000404793	[15,10]	[11,11]	-5	hSpCas9	positive selection	3111164
133370561	133370584		+	24336571	A375	resistance to PLX after 7 days	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.2164084115300716	[17,16]	[12,16]	-6	hSpCas9	positive selection	3111165
133370632	133370655		-	24336571	A375	resistance to PLX after 14 days	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	-0.6801723404344918	[18,21]	[4,5]	-7	hSpCas9	positive selection	3168955
133373260	133373283		+	24336571	A375	resistance to PLX after 14 days	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.6754024417734812	[5,4]	[2,4]	6	hSpCas9	positive selection	3168956
133373235	133373258		+	24336571	A375	resistance to PLX after 14 days	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.7467041832139316	[12,9]	[8,8]	6	hSpCas9	positive selection	3168957
133370561	133370584		+	24336571	A375	resistance to PLX after 14 days	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.5317544560508476	[17,19]	[7,3]	-6	hSpCas9	positive selection	3168958
133370632	133370655		-	24336571	A375	viability after 7 days	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	-0.1858927392224916	[23]	[19,20]	-3	hSpCas9	negative selection	3226748
133373260	133373283		+	24336571	A375	viability after 7 days	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.026951562210281388	[4]	[3,4]	0	hSpCas9	negative selection	3226749
133373235	133373258		+	24336571	A375	viability after 7 days	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.07737167029796284	[12]	[15,10]	1	hSpCas9	negative selection	3226750
133370561	133370584		+	24336571	A375	viability after 7 days	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.059595247442548016	[17]	[17,16]	0	hSpCas9	negative selection	3226751
133370632	133370655		-	24336571	A375	viability after 14 days	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	-0.15229343258748562	[23]	[18,21]	-2	hSpCas9	negative selection	3284541
133373260	133373283		+	24336571	A375	viability after 14 days	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.17738962445133577	[4]	[5,4]	2	hSpCas9	negative selection	3284542
133373235	133373258		+	24336571	A375	viability after 14 days	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.11709238079684861	[12]	[12,9]	-1	hSpCas9	negative selection	3284543
133370561	133370584		+	24336571	A375	viability after 14 days	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.20357490543164297	[17]	[17,19]	2	hSpCas9	negative selection	3284544
133373260	133373283	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	2.351064378122662	[27,31]	[0,0]	8	hSpCas9	positive selection	3347350
133370561	133370584	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.5561613387074759	[111,95]	[0,0]	3	hSpCas9	positive selection	3347351
133373235	133373258	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.32272954077817617	[95,148]	[0,0]	1	hSpCas9	positive selection	3347352
133370632	133370655	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3366552
133369911	133369934	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.19388490038649384	[174,174]	[0,0]	-1	hSpCas9	positive selection	3366553
133370014	133370037	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.26864152467366925	[126,126]	[0,0]	1	hSpCas9	positive selection	3366554
133370704	133370727	10	-	26780180	HT29	viability (Avana library 4 designs)	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	1.1544613571488	[]	[]	4	hSpCas9	negative selection	3421786
133370720	133370743	10	-	26780180	HT29	viability (Avana library 4 designs)	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	0.905344656370149	[]	[]	3	hSpCas9	negative selection	3421787
133370702	133370725	10	-	26780180	HT29	viability (Avana library 4 designs)	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	0.927682713777114	[]	[]	3	hSpCas9	negative selection	3421788
133370687	133370710	10	+	26780180	HT29	viability (Avana library 4 designs)	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	0.359212534878453	[]	[]	1	hSpCas9	negative selection	3421789
133370687	133370710	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	0.626227456313424	[]	[]	0	hSpCas9	negative selection	3502122
133370720	133370743	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	-5.07249054893313	[]	[]	-5	hSpCas9	negative selection	3502123
133370704	133370727	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-1.1000323492894	[]	[]	-1	hSpCas9	negative selection	3502124
133370702	133370725	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	5.21781433762675	[]	[]	8	hSpCas9	negative selection	3502125
133373307	133373330	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	2.80942923924872	[]	[]	4	hSpCas9	negative selection	3502126
133373236	133373259	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	3.2367463408635	[]	[]	5	hSpCas9	negative selection	3502127
133370687	133370710	10	+	26780180	A375	viability (Avana lentiGuide)	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	-4.92318103243733	[]	[]	-8	hSpCas9	negative selection	3610781
133370720	133370743	10	-	26780180	A375	viability (Avana lentiGuide)	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	-9.84923618701494	[]	[]	-9	hSpCas9	negative selection	3610782
133370704	133370727	10	-	26780180	A375	viability (Avana lentiGuide)	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-7.44893208837986	[]	[]	-9	hSpCas9	negative selection	3610783
133370702	133370725	10	-	26780180	A375	viability (Avana lentiGuide)	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	0.353591633240882	[]	[]	0	hSpCas9	negative selection	3610784
133373307	133373330	10	+	26780180	A375	viability (Avana lentiGuide)	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	2.17141065373816	[]	[]	2	hSpCas9	negative selection	3610785
133373236	133373259	10	+	26780180	A375	viability (Avana lentiGuide)	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	1.48937595268215	[]	[]	1	hSpCas9	negative selection	3610786
133370687	133370710	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	-0.3151014708682943	[5]	[4,3]	-5	hSpCas9	positive selection	3719440
133370720	133370743	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	-0.5754027570972928	[5]	[3,2]	-7	hSpCas9	positive selection	3719441
133370704	133370727	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.289397344821182	[4]	[4,3]	-4	hSpCas9	positive selection	3719442
133370702	133370725	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	0.1859498787625568	[5]	[5,5]	5	hSpCas9	positive selection	3719443
133373307	133373330	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.3272048990091719	[4]	[5,5]	8	hSpCas9	positive selection	3719444
133373236	133373259	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.17939319307603205	[5]	[5,5]	5	hSpCas9	positive selection	3719445
133370687	133370710	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCAGTTGGATCAACCCCACGG	ECHS1	ENSG00000127884	0.21813029410322657	[5]	[5,5]	5	hSpCas9	positive selection	3828047
133370720	133370743	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCATCGCAGAAAAAAGAGGG	ECHS1	ENSG00000127884	0.04277673208271354	[4]	[2,4]	0	hSpCas9	positive selection	3828048
133370704	133370727	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.22872169181109206	[4]	[4,4]	6	hSpCas9	positive selection	3828049
133370702	133370725	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGGAAGAATAACACCGTGGGG	ECHS1	ENSG00000127884	0.2788474800042513	[4]	[5,4]	7	hSpCas9	positive selection	3828050
133373307	133373330	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.2717305083191155	[5]	[4,2]	-4	hSpCas9	positive selection	3828051
133373236	133373259	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.20745612272251387	[5]	[3,4]	-3	hSpCas9	positive selection	3828052
133369911	133369934	10	+	26780180	A375	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	1.07297379885744	[]	[]	5	hSpCas9	negative selection	3935450
133370632	133370655	10	+	26780180	A375	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.618017194812417	[]	[]	2	hSpCas9	negative selection	3935451
133373260	133373283	10	+	26780180	A375	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.854551144383251	[]	[]	3	hSpCas9	negative selection	3935452
133373235	133373258	10	+	26780180	A375	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.809375837579507	[]	[]	3	hSpCas9	negative selection	3935453
133370014	133370037	10	-	26780180	A375	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	1.17018139755953	[]	[]	6	hSpCas9	negative selection	3935454
133370561	133370584	10	+	26780180	A375	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	1.98254257906038	[]	[]	9	hSpCas9	negative selection	3935455
133369911	133369934	10	+	26780180	HT29	viability (GeCKOv2 library)	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	1.0140227187461	[]	[]	4	hSpCas9	negative selection	4043416
133370632	133370655	10	+	26780180	HT29	viability (GeCKOv2 library)	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	1.02323369509477	[]	[]	4	hSpCas9	negative selection	4043417
133373260	133373283	10	+	26780180	HT29	viability (GeCKOv2 library)	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.953221627088437	[]	[]	4	hSpCas9	negative selection	4043418
133373235	133373258	10	+	26780180	HT29	viability (GeCKOv2 library)	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	1.25854083595213	[]	[]	6	hSpCas9	negative selection	4043419
133370014	133370037	10	-	26780180	HT29	viability (GeCKOv2 library)	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.755612763534932	[]	[]	3	hSpCas9	negative selection	4043420
133370561	133370584	10	+	26780180	HT29	viability (GeCKOv2 library)	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	2.20746076690696	[]	[]	9	hSpCas9	negative selection	4043421
133370632	133370655	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	0.029909177677536758	[4]	[2,2]	0	hSpCas9	positive selection	4133754
133373260	133373283	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.11355334460720645	[2]	[1,1]	-3	hSpCas9	positive selection	4133755
133373235	133373258	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.13611847092896875	[4]	[1,3]	-3	hSpCas9	positive selection	4133756
133370561	133370584	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.21082365479211532	[3]	[1,2]	-5	hSpCas9	positive selection	4133757
133370632	133370655	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGATTGACGAGCTCAACCAGG	ECHS1	ENSG00000127884	-0.6796374681399671	[4]	[1,1,0,0]	-8	hSpCas9	positive selection	4197776
133373260	133373283	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.4004541699891651	[2]	[0,1,0,0]	-6	hSpCas9	positive selection	4197777
133373235	133373258	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.43958472363490964	[3]	[3,3,1,0]	3	hSpCas9	positive selection	4197778
133370561	133370584	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.05951726025393983	[4]	[2,3,3,0]	-1	hSpCas9	positive selection	4197779
133373260	133373283	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.21518736309448616	[1]	[1,0]	-4	hSpCas9	positive selection	4268092
133370561	133370584	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.16770190050569667	[2]	[2,1]	-3	hSpCas9	positive selection	4268093
133373235	133373258	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.2303423036299124	[2]	[1,1]	-5	hSpCas9	positive selection	4268094
133370632	133370655	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.5943014225595015	[3]	[3,4]	9	hSpCas9	positive selection	4332358
133369911	133369934	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.12880944825312346	[2]	[2,1]	-3	hSpCas9	positive selection	4332359
133370014	133370037	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.02643380228772102	[2]	[2,0]	0	hSpCas9	positive selection	4332360
133369012	133369034	10	-	27760321	OCIAML3	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.39162572551957825	[622,630]	[346,411]	-4	hSpCas9	negative selection	4396601
133370569	133370591	10	-	27760321	OCIAML3	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-1.4311501455099016	[1,495]	[96,53]	-8	hSpCas9	negative selection	4396602
133370655	133370677	10	-	27760321	OCIAML3	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.020507757637972968	[630,509]	[384,534]	0	hSpCas9	negative selection	4396603
133370703	133370725	10	-	27760321	OCIAML3	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.5645061249246219	[192,165]	[121,58]	-5	hSpCas9	negative selection	4396604
133370721	133370743	10	-	27760321	OCIAML3	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.22317707319277913	[100,74]	[63,99]	2	hSpCas9	negative selection	4396605
133369012	133369034	10	-	27760321	OCIAML2	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	0.12684042375451088	[622,630]	[397,763]	1	hSpCas9	negative selection	4480064
133370569	133370591	10	-	27760321	OCIAML2	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-0.6631945919314557	[1,495]	[99,187]	-6	hSpCas9	negative selection	4480065
133370655	133370677	10	-	27760321	OCIAML2	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	-0.10227655768392135	[630,509]	[402,459]	-1	hSpCas9	negative selection	4480066
133370703	133370725	10	-	27760321	OCIAML2	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.7842108506891212	[192,165]	[93,70]	-7	hSpCas9	negative selection	4480067
133370721	133370743	10	-	27760321	OCIAML2	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.3219298963100026	[100,74]	[79,98]	4	hSpCas9	negative selection	4480068
133369012	133369034	10	-	27760321	MV411	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	0.29889899183181257	[622,630]	[444,609]	2	hSpCas9	negative selection	4563527
133370569	133370591	10	-	27760321	MV411	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-2.7024217542011666	[1,495]	[6,57]	-9	hSpCas9	negative selection	4563528
133370655	133370677	10	-	27760321	MV411	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.6370569529509211	[630,509]	[702,400]	5	hSpCas9	negative selection	4563529
133370703	133370725	10	-	27760321	MV411	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-5.506211272435566	[192,165]	[0,4]	-9	hSpCas9	negative selection	4563530
133370721	133370743	10	-	27760321	MV411	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.2222888535553933	[100,74]	[1,164]	1	hSpCas9	negative selection	4563531
133369012	133369034	10	-	27760321	HL60	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	0.4731583741533433	[622,630]	[719,706]	6	hSpCas9	negative selection	4646990
133370569	133370591	10	-	27760321	HL60	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-1.4619932041783814	[1,495]	[82,76]	-8	hSpCas9	negative selection	4646991
133370655	133370677	10	-	27760321	HL60	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	-0.27239769056984225	[630,509]	[242,532]	-3	hSpCas9	negative selection	4646992
133370703	133370725	10	-	27760321	HL60	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.47514126291583847	[192,165]	[77,133]	-5	hSpCas9	negative selection	4646993
133370721	133370743	10	-	27760321	HL60	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.19750638406435428	[100,74]	[104,56]	2	hSpCas9	negative selection	4646994
133369012	133369034	10	-	27760321	HT1080	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-1.168136508055853	[630,492]	[112,84]	-4	hSpCas9	negative selection	4730453
133370569	133370591	10	-	27760321	HT1080	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-3.822434242340997	[495,386]	[10,13]	-8	hSpCas9	negative selection	4730454
133370655	133370677	10	-	27760321	HT1080	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	-0.6690115785790363	[509,397]	[118,107]	-3	hSpCas9	negative selection	4730455
133370703	133370725	10	-	27760321	HT1080	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.31807726925997515	[165,129]	[0,97]	-1	hSpCas9	negative selection	4730456
133370721	133370743	10	-	27760321	HT1080	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	-1.7103607897027815	[74,58]	[0,15]	-6	hSpCas9	negative selection	4730457
133369012	133369034	10	-	27760321	HT29	viability after 7 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.5187609594891835	[630,492]	[664,547,327]	-6	hSpCas9	negative selection	4813916
133370569	133370591	10	-	27760321	HT29	viability after 7 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.2740115440227893	[495,386]	[691,683,682]	4	hSpCas9	negative selection	4813917
133370655	133370677	10	-	27760321	HT29	viability after 7 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	-0.06984990012197168	[509,397]	[755,540,403]	-1	hSpCas9	negative selection	4813918
133370703	133370725	10	-	27760321	HT29	viability after 7 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.037793223820729915	[165,129]	[246,140,176]	0	hSpCas9	negative selection	4813919
133370721	133370743	10	-	27760321	HT29	viability after 7 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.06114518262774826	[74,58]	[55,93,113]	0	hSpCas9	negative selection	4813920
133369012	133369034	10	-	27760321	HT29	viability after 25 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.28012128430240696	[630,492]	[444,585,563]	-3	hSpCas9	negative selection	4897379
133370569	133370591	10	-	27760321	HT29	viability after 25 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.6295568857726601	[495,386]	[796,619,938]	7	hSpCas9	negative selection	4897380
133370655	133370677	10	-	27760321	HT29	viability after 25 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.8907597816725721	[509,397]	[957,945,982]	9	hSpCas9	negative selection	4897381
133370703	133370725	10	-	27760321	HT29	viability after 25 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	0.8652077014093102	[165,129]	[262,414,241]	8	hSpCas9	negative selection	4897382
133370721	133370743	10	-	27760321	HT29	viability after 25 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.9753885266618625	[74,58]	[193,68,189]	9	hSpCas9	negative selection	4897383
133369012	133369034	10	-	27760321	HT29	viability after 22 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.3353848801968528	[630,492]	[630,473,435]	-3	hSpCas9	negative selection	4980842
133370569	133370591	10	-	27760321	HT29	viability after 22 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.6894464802053741	[495,386]	[769,1049,648]	7	hSpCas9	negative selection	4980843
133370655	133370677	10	-	27760321	HT29	viability after 22 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.8172463145551332	[509,397]	[663,1024,1093]	8	hSpCas9	negative selection	4980844
133370703	133370725	10	-	27760321	HT29	viability after 22 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	0.417515314972683	[165,129]	[81,342,264]	4	hSpCas9	negative selection	4980845
133370721	133370743	10	-	27760321	HT29	viability after 22 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.4898903946176456	[74,58]	[139,142,41]	5	hSpCas9	negative selection	4980846
133369012	133369034	10	-	27760321	HT29	viability after 19 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.4976839795282327	[630,492]	[514,355,498]	-4	hSpCas9	negative selection	5064305
133370569	133370591	10	-	27760321	HT29	viability after 19 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.3861256471275783	[495,386]	[612,720,640]	4	hSpCas9	negative selection	5064306
133370655	133370677	10	-	27760321	HT29	viability after 19 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.7082377084959954	[509,397]	[1056,681,827]	7	hSpCas9	negative selection	5064307
133370703	133370725	10	-	27760321	HT29	viability after 19 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	1.0659503862859703	[165,129]	[370,290,400]	9	hSpCas9	negative selection	5064308
133370721	133370743	10	-	27760321	HT29	viability after 19 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.9874324198581883	[74,58]	[48,133,257]	8	hSpCas9	negative selection	5064309
133369012	133369034	10	-	27760321	HT29	viability after 16 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.19974849888517393	[630,492]	[525,715,393]	-2	hSpCas9	negative selection	5147768
133370569	133370591	10	-	27760321	HT29	viability after 16 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.8117329481996287	[495,386]	[758,971,856]	8	hSpCas9	negative selection	5147769
133370655	133370677	10	-	27760321	HT29	viability after 16 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.6589920044214324	[509,397]	[835,653,922]	7	hSpCas9	negative selection	5147770
133370703	133370725	10	-	27760321	HT29	viability after 16 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.21123207694860557	[165,129]	[112,116,196]	-2	hSpCas9	negative selection	5147771
133370721	133370743	10	-	27760321	HT29	viability after 16 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	1.3050911803846783	[74,58]	[180,89,286]	9	hSpCas9	negative selection	5147772
133369012	133369034	10	-	27760321	HT29	viability after 13 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.17411644519332603	[630,492]	[471,703,558]	-2	hSpCas9	negative selection	5231231
133370569	133370591	10	-	27760321	HT29	viability after 13 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.5863488297733748	[495,386]	[810,866,636]	7	hSpCas9	negative selection	5231232
133370655	133370677	10	-	27760321	HT29	viability after 13 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.41703384032588636	[509,397]	[691,721,695]	5	hSpCas9	negative selection	5231233
133370703	133370725	10	-	27760321	HT29	viability after 13 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	0.5184992762879277	[165,129]	[208,128,390]	6	hSpCas9	negative selection	5231234
133370721	133370743	10	-	27760321	HT29	viability after 13 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	0.27295864288663507	[74,58]	[118,37,122]	3	hSpCas9	negative selection	5231235
133369012	133369034	10	-	27760321	HT29	viability after 10 days	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.3341318735775808	[630,492]	[473,615,580]	-4	hSpCas9	negative selection	5314694
133370569	133370591	10	-	27760321	HT29	viability after 10 days	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	0.3808459290954706	[495,386]	[879,561,706]	5	hSpCas9	negative selection	5314695
133370655	133370677	10	-	27760321	HT29	viability after 10 days	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.5605528286384154	[509,397]	[1041,826,642]	7	hSpCas9	negative selection	5314696
133370703	133370725	10	-	27760321	HT29	viability after 10 days	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	0.05487352793834366	[165,129]	[158,227,189]	0	hSpCas9	negative selection	5314697
133370721	133370743	10	-	27760321	HT29	viability after 10 days	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	1.1209096432841354	[74,58]	[70,230,243]	9	hSpCas9	negative selection	5314698
133369012	133369034	10	-	27760321	MOLM13	viability	ATGTTTTACAGTTTGGCGGGGG	ECHS1	ENSG00000127884	-0.3423826920785332	[622,630]	[352,217]	-2	hSpCas9	negative selection	5398157
133370569	133370591	10	-	27760321	MOLM13	viability	GTCCTCACCGGCGGGGATAAGG	ECHS1	ENSG00000127884	-0.49446583761875873	[1,495]	[152,69]	-3	hSpCas9	negative selection	5398158
133370655	133370677	10	-	27760321	MOLM13	viability	CCCTCAATGCACTTTGCGATGG	ECHS1	ENSG00000127884	0.9566669016763687	[630,509]	[986,309]	6	hSpCas9	negative selection	5398159
133370703	133370725	10	-	27760321	MOLM13	viability	GAGGGAAGAATAACACCGTGGG	ECHS1	ENSG00000127884	-0.08618470230540409	[192,165]	[79,107]	0	hSpCas9	negative selection	5398160
133370721	133370743	10	-	27760321	MOLM13	viability	ACATCATCGCAGAAAAAAGAGG	ECHS1	ENSG00000127884	1.2284063701699481	[100,74]	[238,9]	8	hSpCas9	negative selection	5398161
133373103	133373126	10	+	27661255	K562	viability	GTCAGGCGGAAGAGGGGTGTGGG	ECHS1	ENSG00000127884	0.3579200027731697	[371,564]	[623,349]	9	dCas9-KRAB	negative selection	5476480
133373304	133373327	10	+	27661255	K562	viability	GCAGGACAGCAGGACACGCAGGG	ECHS1	ENSG00000127884	0.2697716135354237	[778,784]	[867,654]	8	dCas9-KRAB	negative selection	5476481
133373307	133373330	10	+	27661255	K562	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.15280567415438806	[1317,1224]	[1209,1062]	5	dCas9-KRAB	negative selection	5476482
133373260	133373283	10	+	27260156	BXPC3	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.04090540634013884	[131]	[102,132,167,135]	-1	hSpCas9	negative selection	5540552
133370561	133370584	10	+	27260156	BXPC3	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.2358540362175563	[436]	[302,390,337,544]	-5	hSpCas9	negative selection	5540553
133373235	133373258	10	+	27260156	BXPC3	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.3687691525019727	[282]	[338,398,275,531]	7	hSpCas9	negative selection	5540554
133370632	133370655	10	+	27260156	BXPC3	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.11494482404163414	[556]	[718,534,556,711]	2	hSpCas9	negative selection	5604818
133369911	133369934	10	+	27260156	BXPC3	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.2425297563359554	[399]	[487,473,521,493]	5	hSpCas9	negative selection	5604819
133370014	133370037	10	-	27260156	BXPC3	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.3465633606920717	[206]	[158,108,172,253]	-7	hSpCas9	negative selection	5604820
133373260	133373283	10	+	27260156	A673	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.40190299566869614	[131]	[150,254,202,220]	8	hSpCas9	negative selection	5661803
133370561	133370584	10	+	27260156	A673	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.01221627774287952	[436]	[518,484,520,557]	0	hSpCas9	negative selection	5661804
133373235	133373258	10	+	27260156	A673	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.48275867808424344	[282]	[471,467,471,486]	9	hSpCas9	negative selection	5661805
133370632	133370655	10	+	27260156	A673	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.06912149285441144	[556]	[734,757,719,587]	1	hSpCas9	negative selection	5726069
133369911	133369934	10	+	27260156	A673	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.09437207632633293	[399]	[552,517,527,451]	2	hSpCas9	negative selection	5726070
133370014	133370037	10	-	27260156	A673	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.07341143687629881	[206]	[407,189,217,247]	1	hSpCas9	negative selection	5726071
133373260	133373283	10	+	27260156	A375	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.03809993982677229	[131]	[285,138,122,90]	0	hSpCas9	negative selection	5783054
133370561	133370584	10	+	27260156	A375	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.21381421767885636	[436]	[660,786,499,460]	3	hSpCas9	negative selection	5783055
133373235	133373258	10	+	27260156	A375	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.38682902652937373	[282]	[425,603,381,348]	5	hSpCas9	negative selection	5783056
133370632	133370655	10	+	27260156	A375	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.4682895760354089	[556]	[827,1212,858,756]	7	hSpCas9	negative selection	5847320
133369911	133369934	10	+	27260156	A375	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.5047742544737381	[399]	[535,614,610,855]	7	hSpCas9	negative selection	5847321
133370014	133370037	10	-	27260156	A375	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.45700658146744844	[206]	[104,199,311,98]	-6	hSpCas9	negative selection	5847322
133373260	133373283	10	+	27260156	COLO741	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.5404907284422531	[131]	[376,189,183]	9	hSpCas9	negative selection	5904305
133370561	133370584	10	+	27260156	COLO741	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.11039038690581512	[436]	[604,569,629]	2	hSpCas9	negative selection	5904306
133373235	133373258	10	+	27260156	COLO741	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.38223883423993554	[282]	[356,625,423]	7	hSpCas9	negative selection	5904307
133370632	133370655	10	+	27260156	COLO741	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.33373307384440043	[556]	[1158,843,720]	7	hSpCas9	negative selection	5968571
133369911	133369934	10	+	27260156	COLO741	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.006350455953869322	[399]	[576,458,495]	0	hSpCas9	negative selection	5968572
133370014	133370037	10	-	27260156	COLO741	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.06500571455374948	[206]	[354,208,205]	-1	hSpCas9	negative selection	5968573
133373260	133373283	10	+	27260156	CAL120	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.22629429304433613	[131]	[300,112,178]	3	hSpCas9	negative selection	6025556
133370561	133370584	10	+	27260156	CAL120	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.2312228804808209	[436]	[536,416,446]	-3	hSpCas9	negative selection	6025557
133373235	133373258	10	+	27260156	CAL120	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.3030767728709872	[282]	[197,301,341]	-4	hSpCas9	negative selection	6025558
133370632	133370655	10	+	27260156	CAL120	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.1561470312543798	[556]	[906,601,826]	2	hSpCas9	negative selection	6089822
133369911	133369934	10	+	27260156	CAL120	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.12402751838522685	[399]	[730,411,512]	1	hSpCas9	negative selection	6089823
133370014	133370037	10	-	27260156	CAL120	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.37198121463166123	[206]	[771,132,163]	5	hSpCas9	negative selection	6089824
133373260	133373283	10	+	27260156	CADOES1	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.7699335484738121	[131]	[181,330,158,163]	9	hSpCas9	negative selection	6146807
133370561	133370584	10	+	27260156	CADOES1	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.04204977432893055	[436]	[365,491,334,385]	0	hSpCas9	negative selection	6146808
133373235	133373258	10	+	27260156	CADOES1	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.2703025398112377	[282]	[299,223,315,433]	4	hSpCas9	negative selection	6146809
133370632	133370655	10	+	27260156	CADOES1	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.27458786344750974	[556]	[545,770,489,702]	4	hSpCas9	negative selection	6211073
133369911	133369934	10	+	27260156	CADOES1	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.27702243346626093	[399]	[530,513,359,395]	4	hSpCas9	negative selection	6211074
133370014	133370037	10	-	27260156	CADOES1	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.2820405187157333	[206]	[146,68,211,206]	-5	hSpCas9	negative selection	6211075
133373260	133373283	10	+	27260156	EWS502	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.35647650505243655	[131]	[125,193,105,302]	6	hSpCas9	negative selection	6268058
133370561	133370584	10	+	27260156	EWS502	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.15337599887384284	[436]	[296,435,453,495]	-3	hSpCas9	negative selection	6268059
133373235	133373258	10	+	27260156	EWS502	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.27666242658154133	[282]	[445,311,328,354]	5	hSpCas9	negative selection	6268060
133370632	133370655	10	+	27260156	EWS502	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.03762955820325281	[556]	[609,527,639,647]	0	hSpCas9	negative selection	6332324
133369911	133369934	10	+	27260156	EWS502	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.009555309576826071	[399]	[451,320,506,401]	0	hSpCas9	negative selection	6332325
133370014	133370037	10	-	27260156	EWS502	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.40578231241200324	[206]	[131,157,135,244]	-6	hSpCas9	negative selection	6332326
133373260	133373283	10	+	27260156	EW8	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.42468868686759786	[131]	[161,235,75,113]	7	hSpCas9	negative selection	6389309
133370561	133370584	10	+	27260156	EW8	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.3471833641937948	[436]	[208,359,203,344]	-6	hSpCas9	negative selection	6389310
133373235	133373258	10	+	27260156	EW8	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.2781928852240991	[282]	[317,229,330,227]	5	hSpCas9	negative selection	6389311
133370632	133370655	10	+	27260156	EW8	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.013140024582209253	[556]	[556,303,437,534]	0	hSpCas9	negative selection	6453575
133369911	133369934	10	+	27260156	EW8	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.11120339214674355	[399]	[332,300,265,308]	-2	hSpCas9	negative selection	6453576
133370014	133370037	10	-	27260156	EW8	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.20434383222550623	[206]	[216,105,107,164]	-4	hSpCas9	negative selection	6453577
133373260	133373283	10	+	27260156	CORL105	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.315818878418616	[131]	[233,123,279,147]	6	hSpCas9	negative selection	6510560
133370561	133370584	10	+	27260156	CORL105	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.043555651676046234	[436]	[538,424,495,527]	-1	hSpCas9	negative selection	6510561
133373235	133373258	10	+	27260156	CORL105	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.1483107530641803	[282]	[383,321,398,369]	3	hSpCas9	negative selection	6510562
133370632	133370655	10	+	27260156	CORL105	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.13971317868110483	[556]	[698,994,591,561]	2	hSpCas9	negative selection	6574826
133369911	133369934	10	+	27260156	CORL105	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.3281793220339915	[399]	[498,592,688,582]	6	hSpCas9	negative selection	6574827
133370014	133370037	10	-	27260156	CORL105	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.1602797194604244	[206]	[240,182,211,231]	-3	hSpCas9	negative selection	6574828
133373260	133373283	10	+	27260156	HS294T	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.5880781643263382	[131]	[55,38,67,160]	7	hSpCas9	negative selection	6631811
133370561	133370584	10	+	27260156	HS294T	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.5165831923507868	[436]	[118,72,145,138]	-6	hSpCas9	negative selection	6631812
133373235	133373258	10	+	27260156	HS294T	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.44058322343746537	[282]	[113,214,104,162]	6	hSpCas9	negative selection	6631813
133370632	133370655	10	+	27260156	HS294T	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.49249813660664843	[556]	[307,267,300,340]	6	hSpCas9	negative selection	6696077
133369911	133369934	10	+	27260156	HS294T	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.3802728703006578	[399]	[205,206,188,201]	5	hSpCas9	negative selection	6696078
133370014	133370037	10	-	27260156	HS294T	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.5354209124677562	[206]	[63,39,62,52]	-6	hSpCas9	negative selection	6696079
133373260	133373283	10	+	27260156	HCC44	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.1459890657092311	[131]	[169,144,135,90]	-2	hSpCas9	negative selection	6753062
133370561	133370584	10	+	27260156	HCC44	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.20191770767048622	[436]	[582,466,384,285]	-3	hSpCas9	negative selection	6753063
133373235	133373258	10	+	27260156	HCC44	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.22225893375965244	[282]	[235,462,345,413]	3	hSpCas9	negative selection	6753064
133370632	133370655	10	+	27260156	HCC44	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	-0.22295822949374325	[556]	[514,463,490,679]	-4	hSpCas9	negative selection	6817328
133369911	133369934	10	+	27260156	HCC44	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.15391964393323015	[399]	[783,377,495,396]	2	hSpCas9	negative selection	6817329
133370014	133370037	10	-	27260156	HCC44	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.16411478887627307	[206]	[236,182,272,159]	-3	hSpCas9	negative selection	6817330
133373260	133373283	10	+	27260156	G402	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.2631620982277092	[131]	[111,40,140,228]	-3	hSpCas9	negative selection	6874313
133370561	133370584	10	+	27260156	G402	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.19429513377567276	[436]	[256,533,724,326]	-2	hSpCas9	negative selection	6874314
133373235	133373258	10	+	27260156	G402	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.2584425223110563	[282]	[259,552,586,244]	3	hSpCas9	negative selection	6874315
133370632	133370655	10	+	27260156	G402	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.2904411399363155	[556]	[1212,754,522,878]	3	hSpCas9	negative selection	6938579
133369911	133369934	10	+	27260156	G402	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.42479148093518315	[399]	[629,919,467,613]	5	hSpCas9	negative selection	6938580
133370014	133370037	10	-	27260156	G402	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.09886613248772713	[206]	[276,270,222,308]	1	hSpCas9	negative selection	6938581
133373260	133373283	10	+	27260156	L33	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.033585292334809225	[131]	[135,53,111,94]	0	hSpCas9	negative selection	6995564
133370561	133370584	10	+	27260156	L33	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.411300945518539	[436]	[227,140,251,343]	-7	hSpCas9	negative selection	6995565
133373235	133373258	10	+	27260156	L33	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.07714214964781863	[282]	[300,90,270,240]	1	hSpCas9	negative selection	6995566
133370632	133370655	10	+	27260156	L33	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	-0.10129719432045212	[556]	[553,207,353,451]	-2	hSpCas9	negative selection	7059830
133369911	133369934	10	+	27260156	L33	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.20272054529789912	[399]	[320,250,266,485]	4	hSpCas9	negative selection	7059831
133370014	133370037	10	-	27260156	L33	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.03654720152255675	[206]	[234,87,105,187]	-1	hSpCas9	negative selection	7059832
133373260	133373283	10	+	27260156	K562	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.3708743512574033	[131]	[256,119,137,102]	5	hSpCas9	negative selection	7116815
133370561	133370584	10	+	27260156	K562	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.48829103608687685	[436]	[366,124,230,369]	-5	hSpCas9	negative selection	7116816
133373235	133373258	10	+	27260156	K562	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.01767387874961346	[282]	[453,352,93,126]	0	hSpCas9	negative selection	7116817
133370632	133370655	10	+	27260156	K562	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.21207573439891153	[556]	[790,452,723,356]	2	hSpCas9	negative selection	7181081
133369911	133369934	10	+	27260156	K562	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.5528231442341769	[399]	[627,542,392,525]	7	hSpCas9	negative selection	7181082
133370014	133370037	10	-	27260156	K562	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.1848221832749979	[206]	[243,186,289,124]	2	hSpCas9	negative selection	7181083
133373260	133373283	10	+	27260156	HT29	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.3287060716757435	[131]	[224,157,229,190]	6	hSpCas9	negative selection	7238066
133370561	133370584	10	+	27260156	HT29	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.18177837788050583	[436]	[400,377,528,539]	-4	hSpCas9	negative selection	7238067
133373235	133373258	10	+	27260156	HT29	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.472089271740626	[282]	[481,490,484,451]	8	hSpCas9	negative selection	7238068
133370632	133370655	10	+	27260156	HT29	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.19428568286548858	[556]	[782,1042,768,549]	4	hSpCas9	negative selection	7302332
133369911	133369934	10	+	27260156	HT29	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.3359742233511025	[399]	[682,761,637,410]	6	hSpCas9	negative selection	7302333
133370014	133370037	10	-	27260156	HT29	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.018845113532222957	[206]	[335,175,318,193]	0	hSpCas9	negative selection	7302334
133373260	133373283	10	+	27260156	MHHES1	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.16716232837974254	[131]	[128,107,195,98]	-3	hSpCas9	negative selection	7359317
133370561	133370584	10	+	27260156	MHHES1	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.16486903885290205	[436]	[301,447,759,263]	-3	hSpCas9	negative selection	7359318
133373235	133373258	10	+	27260156	MHHES1	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.15234976651690735	[282]	[321,356,441,297]	3	hSpCas9	negative selection	7359319
133370632	133370655	10	+	27260156	MHHES1	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.29919497796512684	[556]	[1070,827,664,589]	5	hSpCas9	negative selection	7423583
133369911	133369934	10	+	27260156	MHHES1	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.14352820002665273	[399]	[470,598,703,267]	2	hSpCas9	negative selection	7423584
133370014	133370037	10	-	27260156	MHHES1	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.05268775556574701	[206]	[232,286,202,186]	-1	hSpCas9	negative selection	7423585
133373260	133373283	10	+	27260156	MEWO	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.24193657447299133	[131]	[206,125,116]	5	hSpCas9	negative selection	7480568
133370561	133370584	10	+	27260156	MEWO	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.23624094406938828	[436]	[421,284,348]	-5	hSpCas9	negative selection	7480569
133373235	133373258	10	+	27260156	MEWO	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.30047955658492725	[282]	[283,323,361]	6	hSpCas9	negative selection	7480570
133370632	133370655	10	+	27260156	MEWO	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.16106124697949148	[556]	[677,440,647]	3	hSpCas9	negative selection	7544834
133369911	133369934	10	+	27260156	MEWO	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.19634667558450883	[399]	[502,310,199]	-4	hSpCas9	negative selection	7544835
133370014	133370037	10	-	27260156	MEWO	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.537136613157098	[206]	[141,133,125]	-8	hSpCas9	negative selection	7544836
133373260	133373283	10	+	27260156	LNCAPCLONEFGC	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.29770479151006435	[131]	[43,93,101,150]	-5	hSpCas9	negative selection	7601819
133370561	133370584	10	+	27260156	LNCAPCLONEFGC	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.3707579410696177	[436]	[294,242,246,434]	-5	hSpCas9	negative selection	7601820
133373235	133373258	10	+	27260156	LNCAPCLONEFGC	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.1063471926088898	[282]	[312,175,325,301]	1	hSpCas9	negative selection	7601821
133370632	133370655	10	+	27260156	LNCAPCLONEFGC	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.21691058869374003	[556]	[385,500,910,604]	3	hSpCas9	negative selection	7666085
133369911	133369934	10	+	27260156	LNCAPCLONEFGC	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.3864248194125951	[399]	[426,445,601,440]	6	hSpCas9	negative selection	7666086
133370014	133370037	10	-	27260156	LNCAPCLONEFGC	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.6361999984721958	[206]	[129,89,151,116]	-7	hSpCas9	negative selection	7666087
133373260	133373283	10	+	27260156	PANC0327	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.0287938804873904	[131]	[123,95,155,86]	0	hSpCas9	negative selection	7723070
133370561	133370584	10	+	27260156	PANC0327	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.3909999667663349	[436]	[401,261,223,308]	-5	hSpCas9	negative selection	7723071
133373235	133373258	10	+	27260156	PANC0327	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.07396224264216478	[282]	[301,98,380,300]	1	hSpCas9	negative selection	7723072
133370632	133370655	10	+	27260156	PANC0327	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.6590599281379524	[556]	[802,798,582,938]	8	hSpCas9	negative selection	7787336
133369911	133369934	10	+	27260156	PANC0327	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.09409399855126252	[399]	[388,361,384,383]	1	hSpCas9	negative selection	7787337
133370014	133370037	10	-	27260156	PANC0327	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.4612988398279727	[206]	[188,202,375,245]	6	hSpCas9	negative selection	7787338
133373260	133373283	10	+	27260156	NCIH2009	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.4821090803370012	[131]	[343,226,218]	6	hSpCas9	negative selection	7844321
133370561	133370584	10	+	27260156	NCIH2009	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.27068100794780486	[436]	[743,455,1014]	4	hSpCas9	negative selection	7844322
133373235	133373258	10	+	27260156	NCIH2009	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.007250650392044533	[282]	[371,356,446]	0	hSpCas9	negative selection	7844323
133370632	133370655	10	+	27260156	NCIH2009	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.38461580751963065	[556]	[1096,916,1049]	5	hSpCas9	negative selection	7908587
133369911	133369934	10	+	27260156	NCIH2009	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.36881318400814306	[399]	[1169,575,508]	5	hSpCas9	negative selection	7908588
133370014	133370037	10	-	27260156	NCIH2009	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.21766192965996467	[206]	[307,161,288]	-3	hSpCas9	negative selection	7908589
133373260	133373283	10	+	27260156	NCIH1373	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.07805527673283463	[131]	[113,80,131,80]	0	hSpCas9	negative selection	7965572
133370561	133370584	10	+	27260156	NCIH1373	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.26130743268554796	[436]	[444,460,341,100]	-3	hSpCas9	negative selection	7965573
133373235	133373258	10	+	27260156	NCIH1373	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.04357692585283568	[282]	[245,531,252,61]	0	hSpCas9	negative selection	7965574
133370632	133370655	10	+	27260156	NCIH1373	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.7664584671277654	[556]	[946,1568,698,250]	7	hSpCas9	negative selection	8029838
133369911	133369934	10	+	27260156	NCIH1373	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	1.0846927586737467	[399]	[2326,490,566,175]	9	hSpCas9	negative selection	8029839
133370014	133370037	10	-	27260156	NCIH1373	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.27539313667968657	[206]	[541,113,173,93]	2	hSpCas9	negative selection	8029840
133373260	133373283	10	+	27260156	PATU8902	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.5497529896518898	[131]	[493,143,121,359]	6	hSpCas9	negative selection	8086823
133370561	133370584	10	+	27260156	PATU8902	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.3095811425660979	[436]	[1038,364,486,1242]	3	hSpCas9	negative selection	8086824
133373235	133373258	10	+	27260156	PATU8902	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.10369390189890393	[282]	[210,660,640,83]	1	hSpCas9	negative selection	8086825
133370632	133370655	10	+	27260156	PATU8902	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.9791441476692118	[556]	[1197,1120,846,3334]	9	hSpCas9	negative selection	8151089
133369911	133369934	10	+	27260156	PATU8902	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.8376663817125927	[399]	[725,605,1223,1410]	8	hSpCas9	negative selection	8151090
133370014	133370037	10	-	27260156	PATU8902	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.3000199529101004	[206]	[187,329,68,412]	-3	hSpCas9	negative selection	8151091
133373260	133373283	10	+	27260156	PANC1	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.5387622061168362	[131]	[91,266,84,223]	8	hSpCas9	negative selection	8208074
133370561	133370584	10	+	27260156	PANC1	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.7645234312306307	[436]	[182,296,199,216]	-8	hSpCas9	negative selection	8208075
133373235	133373258	10	+	27260156	PANC1	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.14393186571481387	[282]	[273,457,210,179]	2	hSpCas9	negative selection	8208076
133370632	133370655	10	+	27260156	PANC1	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.2893823099809719	[556]	[493,846,664,408]	4	hSpCas9	negative selection	8272340
133369911	133369934	10	+	27260156	PANC1	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.342815638678721	[399]	[336,441,658,321]	5	hSpCas9	negative selection	8272341
133370014	133370037	10	-	27260156	PANC1	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.8401513423079814	[206]	[137,78,51,117]	-8	hSpCas9	negative selection	8272342
133373260	133373283	10	+	27260156	PANC0813	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.2618919228472856	[131]	[193,141,199,206]	4	hSpCas9	negative selection	8329325
133370561	133370584	10	+	27260156	PANC0813	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.1340809819592618	[436]	[543,435,616,648]	2	hSpCas9	negative selection	8329326
133373235	133373258	10	+	27260156	PANC0813	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.14507336603805132	[282]	[515,320,345,303]	2	hSpCas9	negative selection	8329327
133370632	133370655	10	+	27260156	PANC0813	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.6188758376160267	[556]	[941,1675,691,715]	8	hSpCas9	negative selection	8393591
133369911	133369934	10	+	27260156	PANC0813	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.42030539101375053	[399]	[732,542,658,590]	6	hSpCas9	negative selection	8393592
133370014	133370037	10	-	27260156	PANC0813	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.09705564087234508	[206]	[257,252,307,222]	1	hSpCas9	negative selection	8393593
133373260	133373283	10	+	27260156	RDES	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.272308018829996	[131]	[156,126,234,228]	4	hSpCas9	negative selection	8450576
133370561	133370584	10	+	27260156	RDES	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.18581161176356986	[436]	[314,390,530,573]	-3	hSpCas9	negative selection	8450577
133373235	133373258	10	+	27260156	RDES	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.2763480821264959	[282]	[373,290,481,441]	4	hSpCas9	negative selection	8450578
133370632	133370655	10	+	27260156	RDES	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.26486357130844385	[556]	[800,743,688,816]	4	hSpCas9	negative selection	8514842
133369911	133369934	10	+	27260156	RDES	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.28498007302863826	[399]	[448,546,577,697]	4	hSpCas9	negative selection	8514843
133370014	133370037	10	-	27260156	RDES	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.3104075857052251	[206]	[113,201,191,284]	-5	hSpCas9	negative selection	8514844
133373260	133373283	10	+	27260156	PC3	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.21076947535247825	[131]	[102,158,167,191]	4	hSpCas9	negative selection	8571827
133370561	133370584	10	+	27260156	PC3	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.3419234013463893	[436]	[269,283,502,375]	-7	hSpCas9	negative selection	8571828
133373235	133373258	10	+	27260156	PC3	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.3924940968320377	[282]	[256,400,480,393]	7	hSpCas9	negative selection	8571829
133370632	133370655	10	+	27260156	PC3	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	-0.003976682838624096	[556]	[295,462,995,710]	0	hSpCas9	negative selection	8636093
133369911	133369934	10	+	27260156	PC3	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.3951987053830891	[399]	[411,545,812,418]	8	hSpCas9	negative selection	8636094
133370014	133370037	10	-	27260156	PC3	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.3783997671224171	[206]	[89,102,356,182]	-7	hSpCas9	negative selection	8636095
133373260	133373283	10	+	27260156	PATU8988T	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.8538883316962178	[131]	[84,50,67,76]	-8	hSpCas9	negative selection	8693078
133370561	133370584	10	+	27260156	PATU8988T	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.8099656870224905	[436]	[291,288,168,216]	-8	hSpCas9	negative selection	8693079
133373235	133373258	10	+	27260156	PATU8988T	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.2187258393378999	[282]	[206,392,133,220]	-4	hSpCas9	negative selection	8693080
133370632	133370655	10	+	27260156	PATU8988T	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.0026374190958645682	[556]	[449,764,380,587]	0	hSpCas9	negative selection	8757344
133369911	133369934	10	+	27260156	PATU8988T	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.5616297213201941	[399]	[119,453,228,262]	-7	hSpCas9	negative selection	8757345
133370014	133370037	10	-	27260156	PATU8988T	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.7117645061022095	[206]	[75,161,210,34]	-8	hSpCas9	negative selection	8757346
133373260	133373283	10	+	27260156	T47D	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.14426012506199326	[131]	[142,176,182,175]	3	hSpCas9	negative selection	8814329
133370561	133370584	10	+	27260156	T47D	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.13012043497250902	[436]	[408,469,497,482]	-3	hSpCas9	negative selection	8814330
133373235	133373258	10	+	27260156	T47D	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.2317308046906258	[282]	[353,492,332,358]	5	hSpCas9	negative selection	8814331
133370632	133370655	10	+	27260156	T47D	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.07154611606193162	[556]	[648,683,701,691]	1	hSpCas9	negative selection	8878595
133369911	133369934	10	+	27260156	T47D	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.09310735876560422	[399]	[493,478,463,554]	2	hSpCas9	negative selection	8878596
133370014	133370037	10	-	27260156	T47D	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.21668935666066802	[206]	[186,204,164,275]	-5	hSpCas9	negative selection	8878597
133373260	133373283	10	+	27260156	SU8686	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.30598826463633544	[131]	[116,161,176,201]	5	hSpCas9	negative selection	8935580
133370561	133370584	10	+	27260156	SU8686	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.0902559749699487	[436]	[392,319,521,667]	1	hSpCas9	negative selection	8935581
133373235	133373258	10	+	27260156	SU8686	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.29147587040147926	[282]	[284,357,384,349]	5	hSpCas9	negative selection	8935582
133370632	133370655	10	+	27260156	SU8686	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.23927839230387665	[556]	[627,415,713,923]	4	hSpCas9	negative selection	8999846
133369911	133369934	10	+	27260156	SU8686	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.2637737046102326	[399]	[425,406,438,674]	4	hSpCas9	negative selection	8999847
133370014	133370037	10	-	27260156	SU8686	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	0.4399992735686976	[206]	[339,161,293,332]	7	hSpCas9	negative selection	8999848
133373260	133373283	10	+	27260156	SKES1	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.8216772629295046	[131]	[461,118,124,240]	9	hSpCas9	negative selection	9056831
133370561	133370584	10	+	27260156	SKES1	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.45836882099911913	[436]	[374,454,263,209]	-7	hSpCas9	negative selection	9056832
133373235	133373258	10	+	27260156	SKES1	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	-0.07820209694908953	[282]	[347,259,223,247]	-2	hSpCas9	negative selection	9056833
133370632	133370655	10	+	27260156	SKES1	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.27549131683424133	[556]	[785,534,657,699]	6	hSpCas9	negative selection	9121097
133369911	133369934	10	+	27260156	SKES1	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.32521000607771094	[399]	[666,470,547,345]	6	hSpCas9	negative selection	9121098
133370014	133370037	10	-	27260156	SKES1	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.49652614843572196	[206]	[201,102,139,141]	-8	hSpCas9	negative selection	9121099
133373260	133373283	10	+	27260156	TOV112D	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	-0.21371822075407088	[131]	[81,87,208,68]	-4	hSpCas9	negative selection	9178082
133370561	133370584	10	+	27260156	TOV112D	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.39165466812406124	[436]	[329,467,245,322]	-7	hSpCas9	negative selection	9178083
133373235	133373258	10	+	27260156	TOV112D	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.18717305174470178	[282]	[304,326,376,281]	3	hSpCas9	negative selection	9178084
133370632	133370655	10	+	27260156	TOV112D	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	-0.015335684728637972	[556]	[593,835,356,494]	0	hSpCas9	negative selection	9242348
133369911	133369934	10	+	27260156	TOV112D	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	-0.03844943501873202	[399]	[437,464,246,430]	0	hSpCas9	negative selection	9242349
133370014	133370037	10	-	27260156	TOV112D	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.4487837332244391	[206]	[95,315,114,116]	-7	hSpCas9	negative selection	9242350
133373260	133373283	10	+	27260156	TC71	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.5852040810253298	[131]	[255,244,162,183]	9	hSpCas9	negative selection	9299333
133370561	133370584	10	+	27260156	TC71	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	-0.18645523770920353	[436]	[410,462,403,365]	-5	hSpCas9	negative selection	9299334
133373235	133373258	10	+	27260156	TC71	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.306762823181087	[282]	[323,398,284,504]	7	hSpCas9	negative selection	9299335
133370632	133370655	10	+	27260156	TC71	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.04414143643656865	[556]	[666,555,622,614]	1	hSpCas9	negative selection	9363599
133369911	133369934	10	+	27260156	TC71	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.10987252553718692	[399]	[563,325,399,566]	3	hSpCas9	negative selection	9363600
133370014	133370037	10	-	27260156	TC71	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.21556501238770065	[206]	[215,208,140,199]	-5	hSpCas9	negative selection	9363601
133373260	133373283	10	+	27260156	TC32	viability	CGCCAGGCGGGACAGCGAACCGG	ECHS1	ENSG00000127884	0.3081979473808514	[131]	[125,98,146,262]	5	hSpCas9	negative selection	9420584
133370561	133370584	10	+	27260156	TC32	viability	TGCAAAGGCCTTATCCCCGCCGG	ECHS1	ENSG00000127884	0.14012664399060154	[436]	[557,285,610,401]	2	hSpCas9	negative selection	9420585
133373235	133373258	10	+	27260156	TC32	viability	CGCGCACTCACCCGAGGCGAAGG	ECHS1	ENSG00000127884	0.3212970873528608	[282]	[364,134,452,456]	5	hSpCas9	negative selection	9420586
133370632	133370655	10	+	27260156	TC32	viability	CCTGGTTGAGCTCGTCAATCAGG	ECHS1	ENSG00000127884	0.09605265345604919	[556]	[505,474,795,502]	1	hSpCas9	negative selection	9484850
133369911	133369934	10	+	27260156	TC32	viability	CCATTGACAGCAGCGATGACTGG	ECHS1	ENSG00000127884	0.2639689185774833	[399]	[344,402,569,515]	5	hSpCas9	negative selection	9484851
133370014	133370037	10	-	27260156	TC32	viability	GCTAGCTGGAGCTGATATCAAGG	ECHS1	ENSG00000127884	-0.2050087503034277	[206]	[143,97,194,268]	-4	hSpCas9	negative selection	9484852
133366060	133366083	10	-	27869803	HPAFII	viability after 27 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.23035172140363525	[50]	[7,50,NaN]	1	hSpCas9	negative selection	9537394
133366934	133366957	10	-	27869803	HPAFII	viability after 27 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.5265533927171456	[117]	[78,97,NaN]	4	hSpCas9	negative selection	9537395
133368965	133368988	10	-	27869803	HPAFII	viability after 27 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.7743478161692863	[82]	[120,35,NaN]	6	hSpCas9	negative selection	9537396
133369924	133369947	10	+	27869803	HPAFII	viability after 27 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.3089561492810144	[409]	[116,61,NaN]	-7	hSpCas9	negative selection	9537397
133370575	133370598	10	-	27869803	HPAFII	viability after 27 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.01366611274497722	[240]	[110,141,NaN]	0	hSpCas9	negative selection	9537398
133373236	133373259	10	+	27869803	HPAFII	viability after 27 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-2.561195125843738	[446]	[77,7,NaN]	-8	hSpCas9	negative selection	9537399
133366060	133366083	10	-	27869803	HPAFII	viability after 15 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.2820989248898047	[50]	[49,76,NaN]	3	hSpCas9	negative selection	9619843
133366934	133366957	10	-	27869803	HPAFII	viability after 15 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.8655730141600233	[117]	[272,204,NaN]	8	hSpCas9	negative selection	9619844
133368965	133368988	10	-	27869803	HPAFII	viability after 15 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	1.034609269760453	[82]	[392,51,NaN]	9	hSpCas9	negative selection	9619845
133369924	133369947	10	+	27869803	HPAFII	viability after 15 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.8971545837215023	[409]	[399,134,NaN]	-7	hSpCas9	negative selection	9619846
133370575	133370598	10	-	27869803	HPAFII	viability after 15 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.47332463048953477	[240]	[374,349,NaN]	5	hSpCas9	negative selection	9619847
133373236	133373259	10	+	27869803	HPAFII	viability after 15 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-2.01315902981561	[446]	[229,49,NaN]	-9	hSpCas9	negative selection	9619848
133366060	133366083	10	-	27869803	ASPC1	viability after 36 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.3063625506955212	[243]	[52,74,164]	3	hSpCas9	negative selection	9702292
133366934	133366957	10	-	27869803	ASPC1	viability after 36 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.36819781496481685	[395]	[128,93,100]	-4	hSpCas9	negative selection	9702293
133368965	133368988	10	-	27869803	ASPC1	viability after 36 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.33912604263253354	[391]	[48,191,81]	-3	hSpCas9	negative selection	9702294
133369924	133369947	10	+	27869803	ASPC1	viability after 36 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.24498286740743602	[868]	[276,266,486]	2	hSpCas9	negative selection	9702295
133370575	133370598	10	-	27869803	ASPC1	viability after 36 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	1.0740678680761595	[721]	[894,253,488]	8	hSpCas9	negative selection	9702296
133373236	133373259	10	+	27869803	ASPC1	viability after 36 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.29617370626609063	[893]	[158,384,534]	3	hSpCas9	negative selection	9702297
133366060	133366083	10	-	27869803	PATU8988S	viability after 35 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.0031130995696568853	[182]	[92,53,NaN]	0	hSpCas9	negative selection	9784741
133366934	133366957	10	-	27869803	PATU8988S	viability after 35 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.19540530155639735	[279]	[91,104,NaN]	-2	hSpCas9	negative selection	9784742
133368965	133368988	10	-	27869803	PATU8988S	viability after 35 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.11900181240506857	[305]	[62,204,NaN]	1	hSpCas9	negative selection	9784743
133369924	133369947	10	+	27869803	PATU8988S	viability after 35 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.08260583019367007	[847]	[430,291,NaN]	1	hSpCas9	negative selection	9784744
133370575	133370598	10	-	27869803	PATU8988S	viability after 35 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.1344345756449633	[773]	[280,286,NaN]	-1	hSpCas9	negative selection	9784745
133373236	133373259	10	+	27869803	PATU8988S	viability after 35 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-0.3652289202757043	[807]	[313,190,NaN]	-4	hSpCas9	negative selection	9784746
133366060	133366083	10	-	27869803	PATU8988S	viability after 31 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.2003950344822334	[182]	[100,61,NaN]	2	hSpCas9	negative selection	9867190
133366934	133366957	10	-	27869803	PATU8988S	viability after 31 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.44511168794862277	[279]	[151,151,NaN]	5	hSpCas9	negative selection	9867191
133368965	133368988	10	-	27869803	PATU8988S	viability after 31 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.0022763931754681277	[305]	[39,225,NaN]	0	hSpCas9	negative selection	9867192
133369924	133369947	10	+	27869803	PATU8988S	viability after 31 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	0.2638665386256863	[847]	[383,433,NaN]	3	hSpCas9	negative selection	9867193
133370575	133370598	10	-	27869803	PATU8988S	viability after 31 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.3274873537207448	[773]	[208,292,NaN]	-4	hSpCas9	negative selection	9867194
133373236	133373259	10	+	27869803	PATU8988S	viability after 31 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	0.11200743181899875	[807]	[323,378,NaN]	1	hSpCas9	negative selection	9867195
133366060	133366083	10	-	27869803	HPAFII	viability after 35 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	-0.36897904200589204	[50]	[3,37,NaN]	-2	hSpCas9	negative selection	9949639
133366934	133366957	10	-	27869803	HPAFII	viability after 35 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	1.2063988924384645	[117]	[71,211,NaN]	7	hSpCas9	negative selection	9949640
133368965	133368988	10	-	27869803	HPAFII	viability after 35 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	-0.6473861552578446	[82]	[31,20,NaN]	-4	hSpCas9	negative selection	9949641
133369924	133369947	10	+	27869803	HPAFII	viability after 35 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-0.5386770944772384	[409]	[148,135,NaN]	-3	hSpCas9	negative selection	9949642
133370575	133370598	10	-	27869803	HPAFII	viability after 35 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	-0.3610652294119269	[240]	[78,112,NaN]	-2	hSpCas9	negative selection	9949643
133373236	133373259	10	+	27869803	HPAFII	viability after 35 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-3.079669784985311	[446]	[30,21,NaN]	-8	hSpCas9	negative selection	9949644
133366060	133366083	10	-	27869803	HPAFII	viability after 31 days	GATTTGTCCTGTTGAGACACTGG	ECHS1	ENSG00000127884	0.31243361088939836	[50]	[2,70,NaN]	2	hSpCas9	negative selection	10032088
133366934	133366957	10	-	27869803	HPAFII	viability after 31 days	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.8987615792494765	[117]	[66,184,NaN]	6	hSpCas9	negative selection	10032089
133368965	133368988	10	-	27869803	HPAFII	viability after 31 days	TATCATCTATGCCGGTGAGAAGG	ECHS1	ENSG00000127884	0.7434697331297843	[82]	[99,53,NaN]	5	hSpCas9	negative selection	10032090
133369924	133369947	10	+	27869803	HPAFII	viability after 31 days	CGATGACTGGCTTCTTGACCTGG	ECHS1	ENSG00000127884	-1.3091679139719756	[409]	[111,71,NaN]	-7	hSpCas9	negative selection	10032091
133370575	133370598	10	-	27869803	HPAFII	viability after 31 days	GGCCATTGTCCTCACCGGCGGGG	ECHS1	ENSG00000127884	0.3227630693048606	[240]	[116,225,NaN]	2	hSpCas9	negative selection	10032092
133373236	133373259	10	+	27869803	HPAFII	viability after 31 days	GCGCACTCACCCGAGGCGAAGGG	ECHS1	ENSG00000127884	-2.066619836915576	[446]	[34,86,NaN]	-8	hSpCas9	negative selection	10032093
133370704	133370727	10	-	28162770	P31FUJ	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.9332419225554707	[64]	[39]	-6	hSpCas9	negative selection	10147852
133369942	133369965	10	-	28162770	P31FUJ	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-3.337138864229114	[644]	[74]	-9	hSpCas9	negative selection	10147853
133373307	133373330	10	+	28162770	P31FUJ	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.1608616440718983	[101]	[133]	1	hSpCas9	negative selection	10147854
133370611	133370634	10	-	28162770	P31FUJ	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.6387945640902155	[211]	[79]	-8	hSpCas9	negative selection	10147855
133370577	133370600	10	-	28162770	P31FUJ	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.1426043954428004	[154]	[164]	-1	hSpCas9	negative selection	10147856
133366934	133366957	10	-	28162770	P31FUJ	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.4890959416628857	[76]	[126]	5	hSpCas9	negative selection	10147857
133373262	133373285	10	+	28162770	P31FUJ	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	0.0803556808452517	[230]	[286]	0	hSpCas9	negative selection	10147858
133370677	133370700	10	-	28162770	P31FUJ	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.16775867250849896	[411]	[430]	-2	hSpCas9	negative selection	10147859
133370665	133370688	10	+	28162770	P31FUJ	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.2578629996778349	[431]	[606]	2	hSpCas9	negative selection	10147860
133370546	133370569	10	+	28162770	P31FUJ	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.40017454594797464	[393]	[610]	4	hSpCas9	negative selection	10147861
133370704	133370727	10	-	28162770	TF1	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10317218
133369942	133369965	10	-	28162770	TF1	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10317219
133373307	133373330	10	+	28162770	TF1	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10317220
133370611	133370634	10	-	28162770	TF1	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10317221
133370577	133370600	10	-	28162770	TF1	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10317222
133366934	133366957	10	-	28162770	TF1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10317223
133373262	133373285	10	+	28162770	TF1	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	NaN	[NaN]	[338]	1	hSpCas9	negative selection	10317224
133370677	133370700	10	-	28162770	TF1	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	NaN	[NaN]	[736]	1	hSpCas9	negative selection	10317225
133370665	133370688	10	+	28162770	TF1	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	NaN	[NaN]	[224]	1	hSpCas9	negative selection	10317226
133370546	133370569	10	+	28162770	TF1	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10317227
133370704	133370727	10	-	28162770	SKM1	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10486584
133369942	133369965	10	-	28162770	SKM1	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-4.831985786594628	[144]	[8]	-9	hSpCas9	negative selection	10486585
133373307	133373330	10	+	28162770	SKM1	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.11573290107871581	[37]	[61]	-1	hSpCas9	negative selection	10486586
133370611	133370634	10	-	28162770	SKM1	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.7251401587694166	[71]	[76]	-5	hSpCas9	negative selection	10486587
133370577	133370600	10	-	28162770	SKM1	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.23703919730084944	[25]	[38]	-2	hSpCas9	negative selection	10486588
133366934	133366957	10	-	28162770	SKM1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.4581062211707298	[34]	[84]	4	hSpCas9	negative selection	10486589
133373262	133373285	10	+	28162770	SKM1	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	1.2166787701420543	[45]	[188]	9	hSpCas9	negative selection	10486590
133370677	133370700	10	-	28162770	SKM1	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.10998246098603004	[104]	[171]	-1	hSpCas9	negative selection	10486591
133370665	133370688	10	+	28162770	SKM1	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.4141239903160278	[100]	[133]	-3	hSpCas9	negative selection	10486592
133370546	133370569	10	+	28162770	SKM1	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.10644504095296048	[92]	[176]	1	hSpCas9	negative selection	10486593
133370704	133370727	10	-	28162770	SKM1	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10655950
133369942	133369965	10	-	28162770	SKM1	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-4.831985786594628	[144]	[8]	-9	hSpCas9	negative selection	10655951
133373307	133373330	10	+	28162770	SKM1	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.11573290107871581	[37]	[61]	-1	hSpCas9	negative selection	10655952
133370611	133370634	10	-	28162770	SKM1	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.7251401587694166	[71]	[76]	-5	hSpCas9	negative selection	10655953
133370577	133370600	10	-	28162770	SKM1	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.23703919730084944	[25]	[38]	-2	hSpCas9	negative selection	10655954
133366934	133366957	10	-	28162770	SKM1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.4581062211707298	[34]	[84]	4	hSpCas9	negative selection	10655955
133373262	133373285	10	+	28162770	SKM1	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	1.2166787701420543	[45]	[188]	9	hSpCas9	negative selection	10655956
133370677	133370700	10	-	28162770	SKM1	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.10998246098603004	[104]	[171]	-1	hSpCas9	negative selection	10655957
133370665	133370688	10	+	28162770	SKM1	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.4141239903160278	[100]	[133]	-3	hSpCas9	negative selection	10655958
133370546	133370569	10	+	28162770	SKM1	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.10644504095296048	[92]	[176]	1	hSpCas9	negative selection	10655959
133370704	133370727	10	-	28162770	PL21	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.7147127873190784	[48]	[34]	6	hSpCas9	negative selection	10825316
133369942	133369965	10	-	28162770	PL21	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-1.5335433956875846	[438]	[65]	-7	hSpCas9	negative selection	10825317
133373307	133373330	10	+	28162770	PL21	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.43102349671940765	[120]	[70]	4	hSpCas9	negative selection	10825318
133370611	133370634	10	-	28162770	PL21	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.2592920041479772	[208]	[75]	-2	hSpCas9	negative selection	10825319
133370577	133370600	10	-	28162770	PL21	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.3830036716391305	[110]	[62]	3	hSpCas9	negative selection	10825320
133366934	133366957	10	-	28162770	PL21	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.274140195933097	[94]	[49]	2	hSpCas9	negative selection	10825321
133373262	133373285	10	+	28162770	PL21	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-1.1765809532384215	[160]	[30]	-7	hSpCas9	negative selection	10825322
133370677	133370700	10	-	28162770	PL21	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.47708139408382466	[338]	[105]	-3	hSpCas9	negative selection	10825323
133370665	133370688	10	+	28162770	PL21	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.2127235135551867	[220]	[82]	-1	hSpCas9	negative selection	10825324
133370546	133370569	10	+	28162770	PL21	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.054534292242420956	[249]	[112]	0	hSpCas9	negative selection	10825325
133370704	133370727	10	-	28162770	P31FUJ	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.9332419225554707	[64]	[39]	-6	hSpCas9	negative selection	10994682
133369942	133369965	10	-	28162770	P31FUJ	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-3.337138864229114	[644]	[74]	-9	hSpCas9	negative selection	10994683
133373307	133373330	10	+	28162770	P31FUJ	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.1608616440718983	[101]	[133]	1	hSpCas9	negative selection	10994684
133370611	133370634	10	-	28162770	P31FUJ	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.6387945640902155	[211]	[79]	-8	hSpCas9	negative selection	10994685
133370577	133370600	10	-	28162770	P31FUJ	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.1426043954428004	[154]	[164]	-1	hSpCas9	negative selection	10994686
133366934	133366957	10	-	28162770	P31FUJ	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.4890959416628857	[76]	[126]	5	hSpCas9	negative selection	10994687
133373262	133373285	10	+	28162770	P31FUJ	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	0.0803556808452517	[230]	[286]	0	hSpCas9	negative selection	10994688
133370677	133370700	10	-	28162770	P31FUJ	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.16775867250849896	[411]	[430]	-2	hSpCas9	negative selection	10994689
133370665	133370688	10	+	28162770	P31FUJ	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.2578629996778349	[431]	[606]	2	hSpCas9	negative selection	10994690
133370546	133370569	10	+	28162770	P31FUJ	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.40017454594797464	[393]	[610]	4	hSpCas9	negative selection	10994691
133370704	133370727	10	-	28162770	OCIAML5	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	1.6839863293762127	[19]	[115]	9	hSpCas9	negative selection	11164048
133369942	133369965	10	-	28162770	OCIAML5	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-2.451528641280268	[299]	[98]	-8	hSpCas9	negative selection	11164049
133373307	133373330	10	+	28162770	OCIAML5	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.9315397484209982	[69]	[240]	7	hSpCas9	negative selection	11164050
133370611	133370634	10	-	28162770	OCIAML5	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.6948268290527997	[164]	[91]	-7	hSpCas9	negative selection	11164051
133370577	133370600	10	-	28162770	OCIAML5	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.9148023262119596	[46]	[44]	-5	hSpCas9	negative selection	11164052
133366934	133366957	10	-	28162770	OCIAML5	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.7445777349047944	[40]	[123]	6	hSpCas9	negative selection	11164053
133373262	133373285	10	+	28162770	OCIAML5	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	1.0276391954182913	[74]	[275]	8	hSpCas9	negative selection	11164054
133370677	133370700	10	-	28162770	OCIAML5	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	1.2991770095122404	[189]	[843]	9	hSpCas9	negative selection	11164055
133370665	133370688	10	+	28162770	OCIAML5	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.09517076826244997	[180]	[348]	0	hSpCas9	negative selection	11164056
133370546	133370569	10	+	28162770	OCIAML5	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	1.0188048019435398	[145]	[533]	8	hSpCas9	negative selection	11164057
133370704	133370727	10	-	28162770	EOL1	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.4164891462645324	[113]	[44]	-3	hSpCas9	negative selection	11333414
133369942	133369965	10	-	28162770	EOL1	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-3.7297627758413565	[553]	[21]	-9	hSpCas9	negative selection	11333415
133373307	133373330	10	+	28162770	EOL1	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-1.2481867634586021	[256]	[56]	-7	hSpCas9	negative selection	11333416
133370611	133370634	10	-	28162770	EOL1	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.6054885186470284	[334]	[115]	-4	hSpCas9	negative selection	11333417
133370577	133370600	10	-	28162770	EOL1	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.8470360194652475	[238]	[69]	-5	hSpCas9	negative selection	11333418
133366934	133366957	10	-	28162770	EOL1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.15430764914070505	[187]	[88]	-1	hSpCas9	negative selection	11333419
133373262	133373285	10	+	28162770	EOL1	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-0.2726440956407708	[226]	[98]	-2	hSpCas9	negative selection	11333420
133370677	133370700	10	-	28162770	EOL1	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.3455413917972096	[409]	[169]	-3	hSpCas9	negative selection	11333421
133370665	133370688	10	+	28162770	EOL1	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.039110381365745184	[391]	[200]	0	hSpCas9	negative selection	11333422
133370546	133370569	10	+	28162770	EOL1	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.5311402882632335	[330]	[251]	5	hSpCas9	negative selection	11333423
133370704	133370727	10	-	28162770	MOLM13	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	2.20349330025256	[105]	[352]	9	hSpCas9	negative selection	11502780
133369942	133369965	10	-	28162770	MOLM13	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-1.7319251918166594	[633]	[137]	-7	hSpCas9	negative selection	11502781
133373307	133373330	10	+	28162770	MOLM13	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	1.5795347373734878	[173]	[375]	9	hSpCas9	negative selection	11502782
133370611	133370634	10	-	28162770	MOLM13	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.7636746856901193	[262]	[111]	-4	hSpCas9	negative selection	11502783
133370577	133370600	10	-	28162770	MOLM13	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.9140567782675935	[148]	[202]	7	hSpCas9	negative selection	11502784
133366934	133366957	10	-	28162770	MOLM13	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	1.8592108118496151	[137]	[361]	9	hSpCas9	negative selection	11502785
133373262	133373285	10	+	28162770	MOLM13	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	1.1986364529756277	[278]	[462]	8	hSpCas9	negative selection	11502786
133370677	133370700	10	-	28162770	MOLM13	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	1.7956723619624957	[540]	[1357]	9	hSpCas9	negative selection	11502787
133370665	133370688	10	+	28162770	MOLM13	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.2430599747622978	[394]	[337]	1	hSpCas9	negative selection	11502788
133370546	133370569	10	+	28162770	MOLM13	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.8849747094722813	[351]	[469]	6	hSpCas9	negative selection	11502789
133370704	133370727	10	-	28162770	HEL	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.3904280319348423	[87]	[42]	-3	hSpCas9	negative selection	11672146
133369942	133369965	10	-	28162770	HEL	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-4.141241581683438	[550]	[19]	-9	hSpCas9	negative selection	11672147
133373307	133373330	10	+	28162770	HEL	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	0.2669813203833245	[156]	[120]	2	hSpCas9	negative selection	11672148
133370611	133370634	10	-	28162770	HEL	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.5374440748073944	[246]	[108]	-4	hSpCas9	negative selection	11672149
133370577	133370600	10	-	28162770	HEL	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.045803689613124754	[120]	[79]	0	hSpCas9	negative selection	11672150
133366934	133366957	10	-	28162770	HEL	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	0.6531554479456954	[137]	[138]	5	hSpCas9	negative selection	11672151
133373262	133373285	10	+	28162770	HEL	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-0.2295056208012705	[215]	[117]	-2	hSpCas9	negative selection	11672152
133370677	133370700	10	-	28162770	HEL	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.3311483276805116	[437]	[222]	-2	hSpCas9	negative selection	11672153
133370665	133370688	10	+	28162770	HEL	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-1.0597172317392398	[357]	[109]	-6	hSpCas9	negative selection	11672154
133370546	133370569	10	+	28162770	HEL	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	-0.3325991137653741	[347]	[176]	-2	hSpCas9	negative selection	11672155
133370704	133370727	10	-	28162770	MV411	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.019168563109658088	[40]	[34]	0	hSpCas9	negative selection	11841512
133369942	133369965	10	-	28162770	MV411	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-3.5599173712748287	[433]	[30]	-9	hSpCas9	negative selection	11841513
133373307	133373330	10	+	28162770	MV411	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.8105097984265042	[126]	[60]	-5	hSpCas9	negative selection	11841514
133370611	133370634	10	-	28162770	MV411	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.8657730596652158	[211]	[48]	-8	hSpCas9	negative selection	11841515
133370577	133370600	10	-	28162770	MV411	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.4907087017951392	[97]	[115]	4	hSpCas9	negative selection	11841516
133366934	133366957	10	-	28162770	MV411	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.6785618677734478	[94]	[49]	-5	hSpCas9	negative selection	11841517
133373262	133373285	10	+	28162770	MV411	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-1.296882965441035	[174]	[59]	-7	hSpCas9	negative selection	11841518
133370677	133370700	10	-	28162770	MV411	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	0.3870213849737576	[314]	[346]	3	hSpCas9	negative selection	11841519
133370665	133370688	10	+	28162770	MV411	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.8835860998431453	[310]	[141]	-6	hSpCas9	negative selection	11841520
133370546	133370569	10	+	28162770	MV411	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.43574108153994234	[207]	[236]	4	hSpCas9	negative selection	11841521
133370704	133370727	10	-	28162770	MONOMAC1	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.393434059863057	[54]	[47]	-3	hSpCas9	negative selection	12010878
133369942	133369965	10	-	28162770	MONOMAC1	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-2.0327363948111197	[256]	[71]	-8	hSpCas9	negative selection	12010879
133373307	133373330	10	+	28162770	MONOMAC1	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.5307742442365493	[91]	[72]	-4	hSpCas9	negative selection	12010880
133370611	133370634	10	-	28162770	MONOMAC1	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-0.3115966113224093	[130]	[120]	-3	hSpCas9	negative selection	12010881
133370577	133370600	10	-	28162770	MONOMAC1	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	-0.4600712528933476	[77]	[64]	-4	hSpCas9	negative selection	12010882
133366934	133366957	10	-	28162770	MONOMAC1	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.37391460914363295	[51]	[45]	-3	hSpCas9	negative selection	12010883
133373262	133373285	10	+	28162770	MONOMAC1	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-1.5314558861301129	[115]	[45]	-8	hSpCas9	negative selection	12010884
133370677	133370700	10	-	28162770	MONOMAC1	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	0.18260674568409607	[195]	[254]	1	hSpCas9	negative selection	12010885
133370665	133370688	10	+	28162770	MONOMAC1	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.5477239349283398	[189]	[148]	-4	hSpCas9	negative selection	12010886
133370546	133370569	10	+	28162770	MONOMAC1	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	-0.32577016118175645	[163]	[149]	-3	hSpCas9	negative selection	12010887
133370704	133370727	10	-	28162770	OCIAML2	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	-0.18522760637991276	[7]	[38]	-1	hSpCas9	negative selection	12180244
133369942	133369965	10	-	28162770	OCIAML2	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-4.345098943158303	[98]	[26]	-9	hSpCas9	negative selection	12180245
133373307	133373330	10	+	28162770	OCIAML2	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	1.1732263645325633	[15]	[199]	9	hSpCas9	negative selection	12180246
133370611	133370634	10	-	28162770	OCIAML2	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	-1.1102275825401633	[36]	[94]	-6	hSpCas9	negative selection	12180247
133370577	133370600	10	-	28162770	OCIAML2	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.27532455215129964	[23]	[160]	2	hSpCas9	negative selection	12180248
133366934	133366957	10	-	28162770	OCIAML2	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.24356091669624003	[21]	[102]	-2	hSpCas9	negative selection	12180249
133373262	133373285	10	+	28162770	OCIAML2	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-0.27269044763025224	[33]	[155]	-2	hSpCas9	negative selection	12180250
133370677	133370700	10	-	28162770	OCIAML2	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.3802435887850559	[57]	[246]	-3	hSpCas9	negative selection	12180251
133370665	133370688	10	+	28162770	OCIAML2	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	0.24337462048073388	[56]	[373]	2	hSpCas9	negative selection	12180252
133370546	133370569	10	+	28162770	OCIAML2	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	0.5390853295910507	[36]	[297]	5	hSpCas9	negative selection	12180253
133370704	133370727	10	-	28162770	OCIAML3	viability	AAGAGGGAAGAATAACACCGTGG	ECHS1	ENSG00000127884	0.7810317910227618	[15]	[82]	7	hSpCas9	negative selection	12349610
133369942	133369965	10	-	28162770	OCIAML3	viability	GCACTGGGACCACCTCACCCAGG	ECHS1	ENSG00000127884	-1.5940076403241632	[162]	[162]	-8	hSpCas9	negative selection	12349611
133373307	133373330	10	+	28162770	OCIAML3	viability	GGACAGCAGGACACGCAGGGCGG	ECHS1	ENSG00000127884	-0.9159357352115254	[39]	[63]	-6	hSpCas9	negative selection	12349612
133370611	133370634	10	-	28162770	OCIAML3	viability	GGCCCTGAAGACCTTCGAGGAGG	ECHS1	ENSG00000127884	0.04158093346696093	[55]	[173]	0	hSpCas9	negative selection	12349613
133370577	133370600	10	-	28162770	OCIAML3	viability	GGGGCCATTGTCCTCACCGGCGG	ECHS1	ENSG00000127884	0.20744668029375668	[34]	[121]	2	hSpCas9	negative selection	12349614
133366934	133366957	10	-	28162770	OCIAML3	viability	GAAGTCGCTGGCGATGGAGATGG	ECHS1	ENSG00000127884	-0.6913048416790784	[22]	[42]	-5	hSpCas9	negative selection	12349615
133373262	133373285	10	+	28162770	OCIAML3	viability	CCAGGCGGGACAGCGAACCGGGG	ECHS1	ENSG00000127884	-0.38170403661129904	[40]	[94]	-3	hSpCas9	negative selection	12349616
133370677	133370700	10	-	28162770	OCIAML3	viability	GATCCAACTGAACCGCCCCAAGG	ECHS1	ENSG00000127884	-0.12688162989686508	[67]	[187]	-1	hSpCas9	negative selection	12349617
133370665	133370688	10	+	28162770	OCIAML3	viability	GTGCATTGAGGGCCTTGGGGCGG	ECHS1	ENSG00000127884	-0.5531353589086352	[86]	[178]	-4	hSpCas9	negative selection	12349618
133370546	133370569	10	+	28162770	OCIAML3	viability	GCTGCCGCGCGTACCTGCAAAGG	ECHS1	ENSG00000127884	-0.13457602168686594	[75]	[208]	-1	hSpCas9	negative selection	12349619