Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 1974
• Symbol: EIF4A2
• Description: eukaryotic translation initiation factor 4A2

DataSource: http://genomecrispr.dkfz.de/#!/results/EIF4A2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
186784445	186784468	3	+	26472758	Jiyoye	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.8064200915934154	[108]	[46]	-5	hSpCas9	negative selection	49448
186785870	186785893	3	+	26472758	Jiyoye	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	-0.7789209106075845	[156]	[68]	-5	hSpCas9	negative selection	49449
186784620	186784643	3	-	26472758	Jiyoye	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.448434709158952	[37]	[20]	-3	hSpCas9	negative selection	49450
186786199	186786222	3	+	26472758	Jiyoye	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	1.8092738250772191	[27]	[73]	8	hSpCas9	negative selection	49451
186784421	186784444	3	+	26472758	Jiyoye	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	1.159865327965096	[72]	[122]	7	hSpCas9	negative selection	49452
186783624	186783647	3	-	26472758	Jiyoye	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	-0.07825144566436792	[580]	[414]	0	hSpCas9	negative selection	49453
186784456	186784479	3	+	26472758	Jiyoye	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	1.2868811477881614	[24]	[45]	7	hSpCas9	negative selection	49454
186785053	186785076	3	+	26472758	Jiyoye	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.34489710505054116	[127]	[75]	-2	hSpCas9	negative selection	49455
186785995	186786018	3	+	26472758	Jiyoye	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.36078202712395924	[297]	[174]	-3	hSpCas9	negative selection	49456
186786012	186786035	3	-	26472758	Jiyoye	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.22150849664460054	[200]	[129]	-1	hSpCas9	negative selection	49457
186784445	186784468	3	+	26472758	KBM7	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.5772981215287789	[427,225]	[236,210]	6	hSpCas9	negative selection	240566
186785870	186785893	3	+	26472758	KBM7	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.37373551447638664	[236,149]	[44,178]	4	hSpCas9	negative selection	240567
186784620	186784643	3	-	26472758	KBM7	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.10967643493868606	[163,207]	[130,38]	-1	hSpCas9	negative selection	240568
186786199	186786222	3	+	26472758	KBM7	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.7780788405924314	[262,194]	[300,76]	8	hSpCas9	negative selection	240569
186784421	186784444	3	+	26472758	KBM7	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.27051845105841665	[420,409]	[161,162]	-3	hSpCas9	negative selection	240570
186783624	186783647	3	-	26472758	KBM7	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.24730968168530576	[2128,1618]	[1254,840]	2	hSpCas9	negative selection	240571
186784456	186784479	3	+	26472758	KBM7	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-0.6489914643819228	[194,232]	[44,82]	-5	hSpCas9	negative selection	240572
186785053	186785076	3	+	26472758	KBM7	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.18845152222268838	[576,600]	[183,298]	-2	hSpCas9	negative selection	240573
186785995	186786018	3	+	26472758	KBM7	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.030943916092378787	[1515,1504]	[617,827]	0	hSpCas9	negative selection	240574
186786012	186786035	3	-	26472758	KBM7	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.4509538268337884	[1048,1053]	[277,439]	-4	hSpCas9	negative selection	240575
186784445	186784468	3	+	26472758	Raji	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.23291441745745867	[153]	[41]	2	hSpCas9	negative selection	431684
186785870	186785893	3	+	26472758	Raji	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	1.160625556650579	[132]	[68]	8	hSpCas9	negative selection	431685
186784620	186784643	3	-	26472758	Raji	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	1.3849175109025085	[32]	[19]	9	hSpCas9	negative selection	431686
186786199	186786222	3	+	26472758	Raji	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.7291177323435212	[99]	[13]	-5	hSpCas9	negative selection	431687
186784421	186784444	3	+	26472758	Raji	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.8629648077071529	[153]	[64]	7	hSpCas9	negative selection	431688
186783624	186783647	3	-	26472758	Raji	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.7782147977299783	[798]	[317]	7	hSpCas9	negative selection	431689
186784456	186784479	3	+	26472758	Raji	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-0.7127954270415884	[112]	[15]	-5	hSpCas9	negative selection	431690
186785053	186785076	3	+	26472758	Raji	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.33259647577242596	[218]	[63]	3	hSpCas9	negative selection	431691
186785995	186786018	3	+	26472758	Raji	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.123788330409762	[786]	[198]	1	hSpCas9	negative selection	431692
186786012	186786035	3	-	26472758	Raji	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.18807234815257168	[431]	[87]	-1	hSpCas9	negative selection	431693
186784445	186784468	3	+	26472758	K562	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.07218903528765186	[202]	[162]	0	hSpCas9	negative selection	622802
186785870	186785893	3	+	26472758	K562	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.8845227825800641	[230]	[359]	7	hSpCas9	negative selection	622803
186784620	186784643	3	-	26472758	K562	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.8398736022052452	[136]	[206]	7	hSpCas9	negative selection	622804
186786199	186786222	3	+	26472758	K562	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.7066716718526065	[173]	[89]	-4	hSpCas9	negative selection	622805
186784421	186784444	3	+	26472758	K562	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	1.0982862223458967	[326]	[590]	8	hSpCas9	negative selection	622806
186783624	186783647	3	-	26472758	K562	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.02732939480156893	[1402]	[1206]	0	hSpCas9	negative selection	622807
186784456	186784479	3	+	26472758	K562	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-0.555282621847722	[140]	[80]	-3	hSpCas9	negative selection	622808
186785053	186785076	3	+	26472758	K562	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.30183197016538454	[467]	[486]	2	hSpCas9	negative selection	622809
186785995	186786018	3	+	26472758	K562	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.3848839412837941	[928]	[1023]	3	hSpCas9	negative selection	622810
186786012	186786035	3	-	26472758	K562	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	1.0611115143033871	[439]	[774]	8	hSpCas9	negative selection	622811
186784620	186784643	3	-	26627737	DLD1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.961070079104302	[716]	[347,725,272]	8	hSpCas9	negative selection	820866
186784620	186784643	3	-	26627737	GBM cells	viability after 5 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.18908260611214311	[675]	[290,344]	-3	hSpCas9	negative selection	903181
186784620	186784643	3	-	26627737	GBM cells	viability after 13 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.1034384213590902	[675]	[395,296]	-1	hSpCas9	negative selection	985496
186784620	186784643	3	-	26627737	GBM cells	viability after 21 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.7279642789877753	[675]	[227,215]	-6	hSpCas9	negative selection	1067811
186784620	186784643	3	-	26627737	RPE1	viability after 9 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.12679436916184716	[1722]	[481,726]	0	hSpCas9	negative selection	1150126
186784620	186784643	3	-	26627737	RPE1	viability after 12 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.4290219893693681	[1722]	[562,686]	3	hSpCas9	negative selection	1232441
186784620	186784643	3	-	26627737	RPE1	viability after 15 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.4679953049599215	[1722]	[889,465]	3	hSpCas9	negative selection	1314756
186784620	186784643	3	-	26627737	RPE1	viability after 18 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.47407641215231777	[1722]	[583,711]	3	hSpCas9	negative selection	1397071
186784620	186784643	3	-	26627737	HeLa	viability after 8 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.1340032867544385	[849]	[327,385,297]	-1	hSpCas9	negative selection	1479386
186784620	186784643	3	-	26627737	HeLa	viability after 12 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.051618602983299455	[849]	[409,346,260]	0	hSpCas9	negative selection	1561701
186784620	186784643	3	-	26627737	HeLa	viability after 15 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.17296258213425597	[849]	[343,176,406]	-1	hSpCas9	negative selection	1644016
186784620	186784643	3	-	26627737	HeLa	viability after 18 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.18280975823097156	[849]	[227,144,406]	-1	hSpCas9	negative selection	1726331
186784620	186784643	3	-	26627737	HCT116	viability after 6 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	1.4802985713156647	[1288]	[964,344]	7	hSpCas9	negative selection	1808646
186784620	186784643	3	-	26627737	HCT116	viability after 8 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.3050413473313637	[527]	[373,295,407]	3	hSpCas9	negative selection	1890961
186784620	186784643	3	-	26627737	HCT116	viability after 9 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.6537587893936074	[1288]	[531,548]	5	hSpCas9	negative selection	1973276
186784620	186784643	3	-	26627737	HCT116	viability after 12 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.38264338453966895	[527]	[277,335,477]	4	hSpCas9	negative selection	2055591
186784620	186784643	3	-	26627737	HCT116	viability after 15 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.21070768611827173	[527]	[235,209,335]	-2	hSpCas9	negative selection	2137906
186784620	186784643	3	-	26627737	HCT116	viability after 18 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.14243444479763856	[527]	[434,220,188]	1	hSpCas9	negative selection	2220221
186783404	186783427	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCGAGAAATTACCACATTTGGG	EIF4A2	ENSG00000156976	-0.8873991655412475	[138,315]	[26,25]	-5	dCas9-VP64	positive selection	2429088
186783470	186783493	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCTACAAAATTGTGATCCTGG	EIF4A2	ENSG00000156976	1.4037737702790323	[66,72]	[57,21]	5	dCas9-VP64	positive selection	2429089
186783452	186783475	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTATCCGAGGTAACGACCCCAGG	EIF4A2	ENSG00000156976	-1.348483093065513	[79,15]	[3,2]	-7	dCas9-VP64	positive selection	2429090
186783404	186783427	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCGAGAAATTACCACATTTGGG	EIF4A2	ENSG00000156976	0.5533129794462626	[287,295]	[61,212]	4	dCas9-VP64	positive selection	2524343
186783470	186783493	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCTACAAAATTGTGATCCTGG	EIF4A2	ENSG00000156976	-1.0258039338375895	[308,786]	[53,117]	-8	dCas9-VP64	positive selection	2524344
186783452	186783475	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTATCCGAGGTAACGACCCCAGG	EIF4A2	ENSG00000156976	-0.04792386765233525	[53,49]	[10,20]	0	dCas9-VP64	positive selection	2524345
186784422	186784445	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.33153689630532707	[4,4]	[5,5]	7	hSpCas9	positive selection	2985484
186783608	186783631	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	0.5551932910653727	[3,3]	[2,6]	9	hSpCas9	positive selection	2985485
186786200	186786223	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.008014208119824173	[2,2]	[2,1]	0	hSpCas9	positive selection	2985486
186784654	186784677	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	0.1290343326826264	[2,2]	[1,2]	2	hSpCas9	positive selection	2985487
186784422	186784445	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.5179919795355461	[4,4]	[3,0]	-7	hSpCas9	positive selection	3053342
186783608	186783631	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	0.5157324826799576	[3,3]	[3,2]	8	hSpCas9	positive selection	3053343
186786200	186786223	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.11079594319611813	[2,2]	[0,1]	-2	hSpCas9	positive selection	3053344
186784654	186784677	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	0.5142621840998715	[2,2]	[1,3]	8	hSpCas9	positive selection	3053345
186786216	186786239		-	24336571	A375	resistance to PLX after 7 days	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	-0.4358463054848958	[4,4]	[3,2]	-9	hSpCas9	positive selection	3111654
186784461	186784484		-	24336571	A375	resistance to PLX after 7 days	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.12448521843178995	[4,3]	[3,3]	-4	hSpCas9	positive selection	3111655
186786216	186786239		-	24336571	A375	resistance to PLX after 14 days	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	0.2522681701038816	[2,3]	[1,1]	2	hSpCas9	positive selection	3169447
186784461	186784484		-	24336571	A375	resistance to PLX after 14 days	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.38115541135138353	[4,1]	[1,1]	3	hSpCas9	positive selection	3169448
186786216	186786239		-	24336571	A375	viability after 7 days	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	-0.5698459205695355	[7]	[4,4]	-7	hSpCas9	negative selection	3227240
186784461	186784484		-	24336571	A375	viability after 7 days	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.06902361794197587	[4]	[4,3]	-1	hSpCas9	negative selection	3227241
186786216	186786239		-	24336571	A375	viability after 14 days	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	-0.9747547433040166	[7]	[2,3]	-8	hSpCas9	negative selection	3285033
186784461	186784484		-	24336571	A375	viability after 14 days	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.4537491942462166	[4]	[4,1]	-5	hSpCas9	negative selection	3285034
186785059	186785082	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	-0.4061970117849664	[163,241]	[0,0]	-3	hSpCas9	positive selection	3347711
186784620	186784643	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.7419369301486018	[235,275]	[0,0]	-5	hSpCas9	positive selection	3347712
186784461	186784484	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.4851318411761154	[396,459]	[0,2]	-3	hSpCas9	positive selection	3347713
186785053	186785076	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.3425866307412928	[193,193]	[0,0]	-2	hSpCas9	positive selection	3366918
186784621	186784644	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.7925223380047265	[264,264]	[0,0]	-5	hSpCas9	positive selection	3366919
186784445	186784468	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3366920
186784421	186784444	3	+	26780180	HT29	viability (Avana library 4 designs)	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	1.00036232919608	[]	[]	4	hSpCas9	negative selection	3422297
186783607	186783630	3	+	26780180	HT29	viability (Avana library 4 designs)	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	1.60603913123057	[]	[]	6	hSpCas9	negative selection	3422298
186786199	186786222	3	+	26780180	HT29	viability (Avana library 4 designs)	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	1.21839672576953	[]	[]	5	hSpCas9	negative selection	3422299
186784654	186784677	3	-	26780180	HT29	viability (Avana library 4 designs)	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	1.57922805262565	[]	[]	6	hSpCas9	negative selection	3422300
186783607	186783630	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	1.74128835247285	[]	[]	2	hSpCas9	negative selection	3502890
186786199	186786222	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	3.89798879270592	[]	[]	6	hSpCas9	negative selection	3502891
186784421	186784444	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.531249919097459	[]	[]	0	hSpCas9	negative selection	3502892
186784654	186784677	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	4.39533180338965	[]	[]	7	hSpCas9	negative selection	3502893
186784459	186784482	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTCGATGACACCATCGGGG	EIF4A2	ENSG00000156976	2.79036401239944	[]	[]	4	hSpCas9	negative selection	3502894
186784658	186784681	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATAGCTCTCTGCTGAATAGCGG	EIF4A2	ENSG00000156976	-1.18959333103386	[]	[]	-1	hSpCas9	negative selection	3502895
186783607	186783630	3	+	26780180	A375	viability (Avana lentiGuide)	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	3.4822149215148	[]	[]	3	hSpCas9	negative selection	3611549
186786199	186786222	3	+	26780180	A375	viability (Avana lentiGuide)	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.658441814347613	[]	[]	-1	hSpCas9	negative selection	3611550
186784421	186784444	3	+	26780180	A375	viability (Avana lentiGuide)	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	2.92786649149325	[]	[]	3	hSpCas9	negative selection	3611551
186784654	186784677	3	-	26780180	A375	viability (Avana lentiGuide)	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	16.611990392653	[]	[]	8	hSpCas9	negative selection	3611552
186784459	186784482	3	-	26780180	A375	viability (Avana lentiGuide)	TTACCTCGATGACACCATCGGGG	EIF4A2	ENSG00000156976	-5.03909475305729	[]	[]	-8	hSpCas9	negative selection	3611553
186784658	186784681	3	-	26780180	A375	viability (Avana lentiGuide)	AATAGCTCTCTGCTGAATAGCGG	EIF4A2	ENSG00000156976	21.8952304483699	[]	[]	9	hSpCas9	negative selection	3611554
186783607	186783630	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	0.014738525318757134	[4]	[4,3]	0	hSpCas9	positive selection	3720208
186786199	186786222	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.2795416134475949	[4]	[4,5]	7	hSpCas9	positive selection	3720209
186784421	186784444	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.15291394268383957	[5]	[5,4]	-2	hSpCas9	positive selection	3720210
186784654	186784677	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	0.2854142871454355	[4]	[5,5]	8	hSpCas9	positive selection	3720211
186784459	186784482	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTCGATGACACCATCGGGG	EIF4A2	ENSG00000156976	0.08356546471125952	[5]	[5,5]	2	hSpCas9	positive selection	3720212
186784658	186784681	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATAGCTCTCTGCTGAATAGCGG	EIF4A2	ENSG00000156976	-0.16143282360104896	[5]	[5,4]	-3	hSpCas9	positive selection	3720213
186783607	186783630	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCATGTCTGGTGGCTCCGCGG	EIF4A2	ENSG00000156976	-0.11092193185832186	[5]	[4,3]	-1	hSpCas9	positive selection	3828815
186786199	186786222	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.18291010895186557	[4]	[5,3]	4	hSpCas9	positive selection	3828816
186784421	186784444	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.015529693531387945	[6]	[5,5]	0	hSpCas9	positive selection	3828817
186784654	186784677	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTCTGCTGAATAGCGGAAGG	EIF4A2	ENSG00000156976	-0.5608591323105225	[4]	[1,2]	-6	hSpCas9	positive selection	3828818
186784459	186784482	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTCGATGACACCATCGGGG	EIF4A2	ENSG00000156976	0.22584964315431977	[5]	[6,4]	6	hSpCas9	positive selection	3828819
186784658	186784681	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATAGCTCTCTGCTGAATAGCGG	EIF4A2	ENSG00000156976	-0.3772096142495496	[5]	[2,3]	-5	hSpCas9	positive selection	3828820
186784445	186784468	3	+	26780180	A375	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	1.77474563263147	[]	[]	9	hSpCas9	negative selection	3936183
186784620	186784643	3	-	26780180	A375	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.750885674777082	[]	[]	2	hSpCas9	negative selection	3936184
186784621	186784644	3	+	26780180	A375	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.530114517364739	[]	[]	1	hSpCas9	negative selection	3936185
186785053	186785076	3	+	26780180	A375	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	1.01089456580675	[]	[]	5	hSpCas9	negative selection	3936186
186784461	186784484	3	-	26780180	A375	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	1.0357152864068	[]	[]	5	hSpCas9	negative selection	3936187
186785059	186785082	3	-	26780180	A375	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.711118027874905	[]	[]	2	hSpCas9	negative selection	3936188
186784445	186784468	3	+	26780180	HT29	viability (GeCKOv2 library)	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.485946021385795	[]	[]	1	hSpCas9	negative selection	4044149
186784620	186784643	3	-	26780180	HT29	viability (GeCKOv2 library)	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	1.02310791790929	[]	[]	4	hSpCas9	negative selection	4044150
186784621	186784644	3	+	26780180	HT29	viability (GeCKOv2 library)	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.540151068681001	[]	[]	1	hSpCas9	negative selection	4044151
186785053	186785076	3	+	26780180	HT29	viability (GeCKOv2 library)	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	1.24005801650627	[]	[]	6	hSpCas9	negative selection	4044152
186784461	186784484	3	-	26780180	HT29	viability (GeCKOv2 library)	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.143687962958327	[]	[]	-4	hSpCas9	negative selection	4044153
186785059	186785082	3	-	26780180	HT29	viability (GeCKOv2 library)	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.0256181924067047	[]	[]	0	hSpCas9	negative selection	4044154
186786216	186786239	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	-0.5429311358757212	[2]	[0,0]	-9	hSpCas9	positive selection	4134296
186784461	186784484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.0785551377127886	[2]	[2,0]	-2	hSpCas9	positive selection	4134297
186786216	186786239	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATTTGATCCTTAAAACCACGG	EIF4A2	ENSG00000156976	0.9373242999129274	[2]	[0,1,0,3]	6	hSpCas9	positive selection	4198318
186784461	186784484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.9784459500234819	[4]	[0,0,1,0]	-9	hSpCas9	positive selection	4198319
186785059	186785082	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	-0.0885543042135046	[3]	[3,1]	-2	hSpCas9	positive selection	4268496
186784620	186784643	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.015861330050500777	[3]	[2,2]	0	hSpCas9	positive selection	4268497
186784461	186784484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.24654880617921915	[4]	[4,3]	5	hSpCas9	positive selection	4268498
186785053	186785076	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.11234311912215089	[2]	[3,1]	2	hSpCas9	positive selection	4332762
186784621	186784644	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.04093404984649529	[3]	[3,1]	-1	hSpCas9	positive selection	4332763
186784445	186784468	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.1858667353643696	[3]	[2,1]	-4	hSpCas9	positive selection	4332764
186785923	186785945	3	-	27760321	OCIAML3	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4397249
186785996	186786018	3	+	27760321	OCIAML3	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.2864339342027502	[227,214]	[106,187]	-3	hSpCas9	negative selection	4397250
186786568	186786590	3	-	27760321	OCIAML3	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	0.295756179840186	[99,103]	[77,124]	3	hSpCas9	negative selection	4397251
186787118	186787140	3	+	27760321	OCIAML3	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.6723965602452702	[58,59]	[60,91]	7	hSpCas9	negative selection	4397252
186787193	186787215	3	+	27760321	OCIAML3	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.20363984509532562	[642,517]	[581,438]	2	hSpCas9	negative selection	4397253
186785923	186785945	3	-	27760321	OCIAML2	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4480712
186785996	186786018	3	+	27760321	OCIAML2	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.22253500122399816	[227,214]	[213,202]	3	hSpCas9	negative selection	4480713
186786568	186786590	3	-	27760321	OCIAML2	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	0.6371497230616958	[99,103]	[134,120]	8	hSpCas9	negative selection	4480714
186787118	186787140	3	+	27760321	OCIAML2	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.3295610118169612	[58,59]	[58,62]	4	hSpCas9	negative selection	4480715
186787193	186787215	3	+	27760321	OCIAML2	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	-0.19224265389679063	[642,517]	[384,439]	-2	hSpCas9	negative selection	4480716
186785923	186785945	3	-	27760321	MV411	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4564175
186785996	186786018	3	+	27760321	MV411	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	1.3339134802975128	[227,214]	[598,22]	8	hSpCas9	negative selection	4564176
186786568	186786590	3	-	27760321	MV411	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	0.6055259198933212	[99,103]	[0,255]	4	hSpCas9	negative selection	4564177
186787118	186787140	3	+	27760321	MV411	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	1.122424085087559	[58,59]	[112,44]	7	hSpCas9	negative selection	4564178
186787193	186787215	3	+	27760321	MV411	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.9727198825472559	[642,517]	[769,713]	7	hSpCas9	negative selection	4564179
186785923	186785945	3	-	27760321	HL60	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4647638
186785996	186786018	3	+	27760321	HL60	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-1.184737444790575	[227,214]	[51,108]	-8	hSpCas9	negative selection	4647639
186786568	186786590	3	-	27760321	HL60	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.9746514060533067	[99,103]	[12,73]	-7	hSpCas9	negative selection	4647640
186787118	186787140	3	+	27760321	HL60	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	-1.89350849926223	[58,59]	[0,25]	-9	hSpCas9	negative selection	4647641
186787193	186787215	3	+	27760321	HL60	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.10895533206603714	[642,517]	[526,488]	1	hSpCas9	negative selection	4647642
186785923	186785945	3	-	27760321	HT1080	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4731101
186785996	186786018	3	+	27760321	HT1080	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.7563962881249634	[214,167]	[16,75]	-3	hSpCas9	negative selection	4731102
186786568	186786590	3	-	27760321	HT1080	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-1.358807355523068	[103,80]	[0,28]	-5	hSpCas9	negative selection	4731103
186787118	186787140	3	+	27760321	HT1080	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	-4.413977711270596	[59,46]	[0,0]	-8	hSpCas9	negative selection	4731104
186787193	186787215	3	+	27760321	HT1080	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.9673620565115981	[517,403]	[370,345]	5	hSpCas9	negative selection	4731105
186785923	186785945	3	-	27760321	HT29	viability after 7 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4814564
186785996	186786018	3	+	27760321	HT29	viability after 7 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.7199613749835322	[214,167]	[146,90,207]	-7	hSpCas9	negative selection	4814565
186786568	186786590	3	-	27760321	HT29	viability after 7 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.04216806293897868	[103,80]	[67,43,223]	0	hSpCas9	negative selection	4814566
186787118	186787140	3	+	27760321	HT29	viability after 7 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.13374809802845533	[59,46]	[93,59,74]	2	hSpCas9	negative selection	4814567
186787193	186787215	3	+	27760321	HT29	viability after 7 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.1318615393770648	[517,403]	[650,566,726]	2	hSpCas9	negative selection	4814568
186785923	186785945	3	-	27760321	HT29	viability after 25 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4898027
186785996	186786018	3	+	27760321	HT29	viability after 25 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.2290340407385868	[214,167]	[217,195,138]	-2	hSpCas9	negative selection	4898028
186786568	186786590	3	-	27760321	HT29	viability after 25 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.2775425196660204	[103,80]	[35,112,118]	-3	hSpCas9	negative selection	4898029
186787118	186787140	3	+	27760321	HT29	viability after 25 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.5329862589431151	[59,46]	[85,120,54]	6	hSpCas9	negative selection	4898030
186787193	186787215	3	+	27760321	HT29	viability after 25 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.5823246792586801	[517,403]	[738,799,833]	6	hSpCas9	negative selection	4898031
186785923	186785945	3	-	27760321	HT29	viability after 22 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4981490
186785996	186786018	3	+	27760321	HT29	viability after 22 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.8074160737027997	[214,167]	[85,127,166]	-6	hSpCas9	negative selection	4981491
186786568	186786590	3	-	27760321	HT29	viability after 22 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.5077181745425556	[103,80]	[66,64,93]	-5	hSpCas9	negative selection	4981492
186787118	186787140	3	+	27760321	HT29	viability after 22 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	-0.0062024807992688835	[59,46]	[91,26,64]	0	hSpCas9	negative selection	4981493
186787193	186787215	3	+	27760321	HT29	viability after 22 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.2774506371986384	[517,403]	[556,751,630]	3	hSpCas9	negative selection	4981494
186785923	186785945	3	-	27760321	HT29	viability after 19 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5064953
186785996	186786018	3	+	27760321	HT29	viability after 19 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-1.6238592956383964	[214,167]	[81,79,52]	-7	hSpCas9	negative selection	5064954
186786568	186786590	3	-	27760321	HT29	viability after 19 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-1.201737306837238	[103,80]	[93,30,18]	-7	hSpCas9	negative selection	5064955
186787118	186787140	3	+	27760321	HT29	viability after 19 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.30005634494494693	[59,46]	[152,55,26]	3	hSpCas9	negative selection	5064956
186787193	186787215	3	+	27760321	HT29	viability after 19 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.42706943372123307	[517,403]	[750,1167,229]	4	hSpCas9	negative selection	5064957
186785923	186785945	3	-	27760321	HT29	viability after 16 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5148416
186785996	186786018	3	+	27760321	HT29	viability after 16 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.850317507738782	[214,167]	[131,147,76]	-6	hSpCas9	negative selection	5148417
186786568	186786590	3	-	27760321	HT29	viability after 16 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.6898704720578359	[103,80]	[42,3,144]	-6	hSpCas9	negative selection	5148418
186787118	186787140	3	+	27760321	HT29	viability after 16 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	-0.3261017023062598	[59,46]	[71,68,3]	-3	hSpCas9	negative selection	5148419
186787193	186787215	3	+	27760321	HT29	viability after 16 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.37693076092084665	[517,403]	[388,691,900]	4	hSpCas9	negative selection	5148420
186785923	186785945	3	-	27760321	HT29	viability after 13 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5231879
186785996	186786018	3	+	27760321	HT29	viability after 13 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.4212761221478215	[214,167]	[147,153,193]	-5	hSpCas9	negative selection	5231880
186786568	186786590	3	-	27760321	HT29	viability after 13 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	0.3127270054854818	[103,80]	[72,177,147]	4	hSpCas9	negative selection	5231881
186787118	186787140	3	+	27760321	HT29	viability after 13 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.159647842441617	[59,46]	[60,59,85]	2	hSpCas9	negative selection	5231882
186787193	186787215	3	+	27760321	HT29	viability after 13 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.21923120377807526	[517,403]	[624,627,614]	2	hSpCas9	negative selection	5231883
186785923	186785945	3	-	27760321	HT29	viability after 10 days	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5315342
186785996	186786018	3	+	27760321	HT29	viability after 10 days	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.5817124343112178	[214,167]	[150,157,169]	-6	hSpCas9	negative selection	5315343
186786568	186786590	3	-	27760321	HT29	viability after 10 days	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.3864902412523512	[103,80]	[50,84,127]	-5	hSpCas9	negative selection	5315344
186787118	186787140	3	+	27760321	HT29	viability after 10 days	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	0.8500887802866659	[59,46]	[248,36,73]	9	hSpCas9	negative selection	5315345
186787193	186787215	3	+	27760321	HT29	viability after 10 days	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	0.18681213615368053	[517,403]	[445,662,851]	2	hSpCas9	negative selection	5315346
186785923	186785945	3	-	27760321	MOLM13	viability	CCAATGCAGGCATGACAAGTGG	EIF4A2	ENSG00000156976	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5398805
186785996	186786018	3	+	27760321	MOLM13	viability	TATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.0022732577364109607	[227,214]	[186,71]	0	hSpCas9	negative selection	5398806
186786568	186786590	3	-	27760321	MOLM13	viability	TTTTCACCAGAATTCGAATTGG	EIF4A2	ENSG00000156976	-0.5453387960014733	[99,103]	[84,0]	-3	hSpCas9	negative selection	5398807
186787118	186787140	3	+	27760321	MOLM13	viability	ACATTACAGGAATGGAAGTTGG	EIF4A2	ENSG00000156976	-1.4263201058146255	[58,59]	[11,12]	-7	hSpCas9	negative selection	5398808
186787193	186787215	3	+	27760321	MOLM13	viability	CTCAATACGAGGCGCAAGGTGG	EIF4A2	ENSG00000156976	-0.7866577452271584	[642,517]	[251,134]	-5	hSpCas9	negative selection	5398809
186783567	186783590	3	+	27661255	K562	viability	GCGCCGCTGTCTTTTCAGTCGGG	EIF4A2	ENSG00000156976	-0.5529894616769608	[219,269]	[167,102]	-8	dCas9-KRAB	negative selection	5476976
186783618	186783641	3	+	27661255	K562	viability	GTGGCTCCGCGGATTATAACAGG	EIF4A2	ENSG00000156976	-0.3429383209516894	[740,753]	[495,448]	-7	dCas9-KRAB	negative selection	5476977
186783817	186783840	3	+	27661255	K562	viability	GGACGGTGGTGCGAAAGCAGTGG	EIF4A2	ENSG00000156976	0.016210597887830303	[1103,1145]	[898,915]	0	dCas9-KRAB	negative selection	5476978
186785265	186785288	3	+	27661255	K562	viability	GTATGCAGGTATGGTTTGTAGGG	EIF4A2	ENSG00000156976	-0.08053582679798632	[1479,1520]	[1261,1022]	-3	dCas9-KRAB	negative selection	5476979
186783570	186783593	3	-	27661255	K562	viability	GCGCCCGACTGAAAAGACAGCGG	EIF4A2	ENSG00000156976	-0.7136541051592895	[406,452]	[221,197]	-8	dCas9-KRAB	negative selection	5476980
186783989	186784012	3	-	27661255	K562	viability	GGACCCTCCCCCAACTCGTGTGG	EIF4A2	ENSG00000156976	0.3885591160237314	[99,152]	[140,122]	9	dCas9-KRAB	negative selection	5476981
186785058	186785081	3	-	27661255	K562	viability	GGGGGCCAATACTAGTGCTTGGG	EIF4A2	ENSG00000156976	-0.044524961164099264	[983,794]	[764,628]	-2	dCas9-KRAB	negative selection	5476982
186785311	186785334	3	-	27661255	K562	viability	GTACATCCAAGAGAGCGCTTCGG	EIF4A2	ENSG00000156976	0.25471141777912365	[11,5]	[12,4]	8	dCas9-KRAB	negative selection	5476983
186785059	186785082	3	-	27260156	BXPC3	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.38430322358582025	[667]	[957,830,866,992]	8	hSpCas9	negative selection	5540956
186784620	186784643	3	-	27260156	BXPC3	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.03172421476214615	[757]	[851,623,817,806]	0	hSpCas9	negative selection	5540957
186784461	186784484	3	-	27260156	BXPC3	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.29916106322738933	[1454]	[1803,1782,1862,2059]	6	hSpCas9	negative selection	5540958
186785053	186785076	3	+	27260156	BXPC3	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.15236302877107066	[325]	[278,310,279,363]	-4	hSpCas9	negative selection	5605222
186784621	186784644	3	+	27260156	BXPC3	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.09559766448879464	[574]	[563,659,613,746]	2	hSpCas9	negative selection	5605223
186784445	186784468	3	+	27260156	BXPC3	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.0008375262123472282	[595]	[616,458,672,766]	0	hSpCas9	negative selection	5605224
186785059	186785082	3	-	27260156	A673	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.29527038686086626	[667]	[1103,1007,946,883]	7	hSpCas9	negative selection	5662207
186784620	186784643	3	-	27260156	A673	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.10268141075151294	[757]	[936,860,835,759]	-3	hSpCas9	negative selection	5662208
186784461	186784484	3	-	27260156	A673	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.20898835286568085	[1454]	[2297,1664,2144,2004]	5	hSpCas9	negative selection	5662209
186785053	186785076	3	+	27260156	A673	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.15057210207120142	[325]	[424,391,392,532]	3	hSpCas9	negative selection	5726473
186784621	186784644	3	+	27260156	A673	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.059945533418798796	[574]	[881,651,569,564]	-1	hSpCas9	negative selection	5726474
186784445	186784468	3	+	27260156	A673	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.21289677277659277	[595]	[637,555,662,614]	-5	hSpCas9	negative selection	5726475
186785059	186785082	3	-	27260156	A375	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.12452793255329642	[667]	[1013,1034,694,699]	1	hSpCas9	negative selection	5783458
186784620	186784643	3	-	27260156	A375	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.305954172882179	[757]	[864,859,571,599]	-4	hSpCas9	negative selection	5783459
186784461	186784484	3	-	27260156	A375	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.027461622226972127	[1454]	[1724,1806,1641,1525]	0	hSpCas9	negative selection	5783460
186785053	186785076	3	+	27260156	A375	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.19662533761866713	[325]	[539,340,540,322]	3	hSpCas9	negative selection	5847724
186784621	186784644	3	+	27260156	A375	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.18206968667450618	[574]	[837,965,750,544]	2	hSpCas9	negative selection	5847725
186784445	186784468	3	+	27260156	A375	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.7357625488991523	[595]	[486,555,310,344]	-7	hSpCas9	negative selection	5847726
186785059	186785082	3	-	27260156	COLO741	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.19885420596416514	[667]	[1071,998,880]	4	hSpCas9	negative selection	5904709
186784620	186784643	3	-	27260156	COLO741	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.04224167558136982	[757]	[1300,1012,721]	0	hSpCas9	negative selection	5904710
186784461	186784484	3	-	27260156	COLO741	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.16919855425806385	[1454]	[2241,2015,2025]	3	hSpCas9	negative selection	5904711
186785053	186785076	3	+	27260156	COLO741	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.14479366801438498	[325]	[376,466,291]	-3	hSpCas9	negative selection	5968975
186784621	186784644	3	+	27260156	COLO741	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.07722922028095813	[574]	[925,662,748]	1	hSpCas9	negative selection	5968976
186784445	186784468	3	+	27260156	COLO741	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.09474425189766447	[595]	[822,668,658]	-2	hSpCas9	negative selection	5968977
186785059	186785082	3	-	27260156	CAL120	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.4074655338692533	[667]	[1660,897,836]	6	hSpCas9	negative selection	6025960
186784620	186784643	3	-	27260156	CAL120	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.3176274477172062	[757]	[1265,1390,887]	5	hSpCas9	negative selection	6025961
186784461	186784484	3	-	27260156	CAL120	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.074671697746584	[1454]	[1800,1461,1902]	-1	hSpCas9	negative selection	6025962
186785053	186785076	3	+	27260156	CAL120	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.4640221673772774	[325]	[339,250,297]	-6	hSpCas9	negative selection	6090226
186784621	186784644	3	+	27260156	CAL120	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.25582030291891633	[574]	[1086,729,781]	4	hSpCas9	negative selection	6090227
186784445	186784468	3	+	27260156	CAL120	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.2368087074816883	[595]	[958,433,545]	-3	hSpCas9	negative selection	6090228
186785059	186785082	3	-	27260156	CADOES1	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.3424423912041995	[667]	[901,755,845,640]	6	hSpCas9	negative selection	6147211
186784620	186784643	3	-	27260156	CADOES1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.10472165194942029	[757]	[574,572,754,721]	-2	hSpCas9	negative selection	6147212
186784461	186784484	3	-	27260156	CADOES1	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.16028593307860772	[1454]	[1461,1437,1558,1592]	2	hSpCas9	negative selection	6147213
186785053	186785076	3	+	27260156	CADOES1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.08144543877010146	[325]	[249,324,294,275]	-1	hSpCas9	negative selection	6211477
186784621	186784644	3	+	27260156	CADOES1	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.28089159849774914	[574]	[582,756,668,587]	5	hSpCas9	negative selection	6211478
186784445	186784468	3	+	27260156	CADOES1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.6517748579669398	[595]	[442,235,271,463]	-8	hSpCas9	negative selection	6211479
186785059	186785082	3	-	27260156	EWS502	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.2860446251453451	[667]	[901,901,897,729]	5	hSpCas9	negative selection	6268462
186784620	186784643	3	-	27260156	EWS502	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.08160479969810619	[757]	[443,926,785,917]	-1	hSpCas9	negative selection	6268463
186784461	186784484	3	-	27260156	EWS502	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.07295570954119723	[1454]	[1588,1231,1316,1727]	-1	hSpCas9	negative selection	6268464
186785053	186785076	3	+	27260156	EWS502	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.1240815160586457	[325]	[364,237,405,250]	-2	hSpCas9	negative selection	6332728
186784621	186784644	3	+	27260156	EWS502	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.0797973837867959	[574]	[563,644,793,575]	1	hSpCas9	negative selection	6332729
186784445	186784468	3	+	27260156	EWS502	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.7146861125466197	[595]	[404,477,311,330]	-8	hSpCas9	negative selection	6332730
186785059	186785082	3	-	27260156	EW8	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.2430932855461534	[667]	[731,653,528,674]	4	hSpCas9	negative selection	6389713
186784620	186784643	3	-	27260156	EW8	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.01900078390666471	[757]	[609,555,565,697]	0	hSpCas9	negative selection	6389714
186784461	186784484	3	-	27260156	EW8	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.20922403648723287	[1454]	[1445,1649,1136,1264]	4	hSpCas9	negative selection	6389715
186785053	186785076	3	+	27260156	EW8	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.17094681596557826	[325]	[267,227,250,191]	-3	hSpCas9	negative selection	6453979
186784621	186784644	3	+	27260156	EW8	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.32963786236565584	[574]	[663,606,613,459]	6	hSpCas9	negative selection	6453980
186784445	186784468	3	+	27260156	EW8	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.6092576153338315	[595]	[432,230,304,310]	-8	hSpCas9	negative selection	6453981
186785059	186785082	3	-	27260156	CORL105	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.3723181164121401	[667]	[1078,935,1071,974]	7	hSpCas9	negative selection	6510964
186784620	186784643	3	-	27260156	CORL105	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.28161681355459534	[757]	[1066,1065,1234,970]	5	hSpCas9	negative selection	6510965
186784461	186784484	3	-	27260156	CORL105	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.1345940674335866	[1454]	[1501,1493,1795,1451]	-3	hSpCas9	negative selection	6510966
186785053	186785076	3	+	27260156	CORL105	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.12712288503161295	[325]	[425,294,383,301]	-2	hSpCas9	negative selection	6575230
186784621	186784644	3	+	27260156	CORL105	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.16806579133198923	[574]	[610,522,655,616]	-3	hSpCas9	negative selection	6575231
186784445	186784468	3	+	27260156	CORL105	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.6304546360790371	[595]	[446,356,556,459]	-8	hSpCas9	negative selection	6575232
186785059	186785082	3	-	27260156	HS294T	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.44471885384596455	[667]	[286,365,374,388]	6	hSpCas9	negative selection	6632215
186784620	186784643	3	-	27260156	HS294T	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.05053912192753973	[757]	[258,395,276,277]	0	hSpCas9	negative selection	6632216
186784461	186784484	3	-	27260156	HS294T	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.018482835284468813	[1454]	[469,482,717,628]	0	hSpCas9	negative selection	6632217
186785053	186785076	3	+	27260156	HS294T	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.16368094893591656	[325]	[72,73,159,154]	-2	hSpCas9	negative selection	6696481
186784621	186784644	3	+	27260156	HS294T	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.29100723602136147	[574]	[261,337,222,260]	4	hSpCas9	negative selection	6696482
186784445	186784468	3	+	27260156	HS294T	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.621337756134874	[595]	[184,124,111,178]	-7	hSpCas9	negative selection	6696483
186785059	186785082	3	-	27260156	HCC44	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.43603507575429534	[667]	[1106,904,1107,999]	7	hSpCas9	negative selection	6753466
186784620	186784643	3	-	27260156	HCC44	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.014957006397991801	[757]	[947,817,1026,711]	0	hSpCas9	negative selection	6753467
186784461	186784484	3	-	27260156	HCC44	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.06572580377827819	[1454]	[1952,1110,2116,1298]	-1	hSpCas9	negative selection	6753468
186785053	186785076	3	+	27260156	HCC44	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.46764412589553167	[325]	[451,551,419,581]	7	hSpCas9	negative selection	6817732
186784621	186784644	3	+	27260156	HCC44	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.15278422868011693	[574]	[549,880,855,587]	2	hSpCas9	negative selection	6817733
186784445	186784468	3	+	27260156	HCC44	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.8735408087234924	[595]	[396,318,375,386]	-8	hSpCas9	negative selection	6817734
186785059	186785082	3	-	27260156	G402	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.33701926221560097	[667]	[914,728,1484,954]	4	hSpCas9	negative selection	6874717
186784620	186784643	3	-	27260156	G402	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.11821191798385566	[757]	[1166,969,1077,826]	1	hSpCas9	negative selection	6874718
186784461	186784484	3	-	27260156	G402	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.2085812640613689	[1454]	[1669,2330,2479,1695]	2	hSpCas9	negative selection	6874719
186785053	186785076	3	+	27260156	G402	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.003791550556135559	[325]	[349,305,490,424]	0	hSpCas9	negative selection	6938983
186784621	186784644	3	+	27260156	G402	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.48057869772991957	[574]	[1255,1195,815,709]	6	hSpCas9	negative selection	6938984
186784445	186784468	3	+	27260156	G402	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-1.268306446036696	[595]	[570,237,265,172]	-8	hSpCas9	negative selection	6938985
186785059	186785082	3	-	27260156	L33	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.16163953830627453	[667]	[602,338,535,709]	3	hSpCas9	negative selection	6995968
186784620	186784643	3	-	27260156	L33	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.27587817885477584	[757]	[1045,407,523,792]	6	hSpCas9	negative selection	6995969
186784461	186784484	3	-	27260156	L33	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.3258558230283981	[1454]	[984,520,794,1126]	-6	hSpCas9	negative selection	6995970
186785053	186785076	3	+	27260156	L33	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.09226942337523258	[325]	[396,136,166,390]	2	hSpCas9	negative selection	7060234
186784621	186784644	3	+	27260156	L33	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.12202888715331417	[574]	[582,249,287,460]	-3	hSpCas9	negative selection	7060235
186784445	186784468	3	+	27260156	L33	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.4911849575858215	[595]	[312,223,279,393]	-8	hSpCas9	negative selection	7060236
186785059	186785082	3	-	27260156	K562	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.057319728346458265	[667]	[483,775,630,575]	0	hSpCas9	negative selection	7117219
186784620	186784643	3	-	27260156	K562	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.41715628523795145	[757]	[224,598,543,613]	-5	hSpCas9	negative selection	7117220
186784461	186784484	3	-	27260156	K562	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.05914923875322864	[1454]	[1321,1612,1178,1280]	0	hSpCas9	negative selection	7117221
186785053	186785076	3	+	27260156	K562	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.27429579629189904	[325]	[316,277,325,63]	-3	hSpCas9	negative selection	7181485
186784621	186784644	3	+	27260156	K562	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.34149309665597916	[574]	[839,863,564,373]	4	hSpCas9	negative selection	7181486
186784445	186784468	3	+	27260156	K562	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.40965287979944026	[595]	[417,481,166,515]	-5	hSpCas9	negative selection	7181487
186785059	186785082	3	-	27260156	HT29	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.37012292922024115	[667]	[1019,1354,750,1083]	7	hSpCas9	negative selection	7238470
186784620	186784643	3	-	27260156	HT29	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.05124253388089528	[757]	[958,1162,921,804]	1	hSpCas9	negative selection	7238471
186784461	186784484	3	-	27260156	HT29	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.18818865770272097	[1454]	[2203,2077,1940,1861]	3	hSpCas9	negative selection	7238472
186785053	186785076	3	+	27260156	HT29	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.24663612881648606	[325]	[499,513,512,368]	5	hSpCas9	negative selection	7302736
186784621	186784644	3	+	27260156	HT29	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.14004709855103892	[574]	[776,915,693,708]	2	hSpCas9	negative selection	7302737
186784445	186784468	3	+	27260156	HT29	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.18099175439295245	[595]	[779,683,531,577]	-4	hSpCas9	negative selection	7302738
186785059	186785082	3	-	27260156	MHHES1	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	-0.009717803802042402	[667]	[975,656,723,654]	0	hSpCas9	negative selection	7359721
186784620	186784643	3	-	27260156	MHHES1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.08806075855492312	[757]	[947,882,765,656]	-2	hSpCas9	negative selection	7359722
186784461	186784484	3	-	27260156	MHHES1	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.1555405885091039	[1454]	[2023,2084,1721,1543]	3	hSpCas9	negative selection	7359723
186785053	186785076	3	+	27260156	MHHES1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.13808477061537805	[325]	[327,365,153,451]	-3	hSpCas9	negative selection	7423987
186784621	186784644	3	+	27260156	MHHES1	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.12967646860583126	[574]	[819,596,449,528]	-2	hSpCas9	negative selection	7423988
186784445	186784468	3	+	27260156	MHHES1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.16280341135034443	[595]	[736,584,801,338]	-3	hSpCas9	negative selection	7423989
186785059	186785082	3	-	27260156	MEWO	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	-0.03903803493784891	[667]	[743,602,503]	-1	hSpCas9	negative selection	7480972
186784620	186784643	3	-	27260156	MEWO	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.17099154797083194	[757]	[709,642,551]	-4	hSpCas9	negative selection	7480973
186784461	186784484	3	-	27260156	MEWO	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.32635163934123423	[1454]	[1746,1859,1519]	7	hSpCas9	negative selection	7480974
186785053	186785076	3	+	27260156	MEWO	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.18384916080783847	[325]	[481,247,335]	4	hSpCas9	negative selection	7545238
186784621	186784644	3	+	27260156	MEWO	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.18860235113953427	[574]	[734,759,366]	4	hSpCas9	negative selection	7545239
186784445	186784468	3	+	27260156	MEWO	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.3193675083103299	[595]	[667,312,402]	-6	hSpCas9	negative selection	7545240
186785059	186785082	3	-	27260156	LNCAPCLONEFGC	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.29087845193826334	[667]	[640,783,910,648]	4	hSpCas9	negative selection	7602223
186784620	186784643	3	-	27260156	LNCAPCLONEFGC	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.12334413094812735	[757]	[749,588,1039,665]	2	hSpCas9	negative selection	7602224
186784461	186784484	3	-	27260156	LNCAPCLONEFGC	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.26775941863578967	[1454]	[969,1236,1240,944]	-4	hSpCas9	negative selection	7602225
186785053	186785076	3	+	27260156	LNCAPCLONEFGC	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.06566843258219168	[325]	[224,350,382,180]	-1	hSpCas9	negative selection	7666489
186784621	186784644	3	+	27260156	LNCAPCLONEFGC	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.2840649254272968	[574]	[551,472,770,772]	4	hSpCas9	negative selection	7666490
186784445	186784468	3	+	27260156	LNCAPCLONEFGC	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.7011267132037267	[595]	[305,339,344,338]	-8	hSpCas9	negative selection	7666491
186785059	186785082	3	-	27260156	PANC0327	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.679112138260453	[667]	[1076,741,806,1210]	8	hSpCas9	negative selection	7723474
186784620	186784643	3	-	27260156	PANC0327	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.1528438733977543	[757]	[767,470,557,655]	-2	hSpCas9	negative selection	7723475
186784461	186784484	3	-	27260156	PANC0327	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.017116749234199258	[1454]	[1883,1048,1273,980]	0	hSpCas9	negative selection	7723476
186785053	186785076	3	+	27260156	PANC0327	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.2785909836177518	[325]	[383,196,142,247]	-4	hSpCas9	negative selection	7787740
186784621	186784644	3	+	27260156	PANC0327	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.22748526852800965	[574]	[623,559,639,574]	3	hSpCas9	negative selection	7787741
186784445	186784468	3	+	27260156	PANC0327	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.10864869467419569	[595]	[477,619,354,492]	-2	hSpCas9	negative selection	7787742
186785059	186785082	3	-	27260156	NCIH2009	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.5672131020733167	[667]	[1999,1059,1213]	7	hSpCas9	negative selection	7844725
186784620	186784643	3	-	27260156	NCIH2009	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.2728188679345842	[757]	[1313,1342,1184]	4	hSpCas9	negative selection	7844726
186784461	186784484	3	-	27260156	NCIH2009	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.0031933091857809792	[1454]	[2256,2370,1517]	0	hSpCas9	negative selection	7844727
186785053	186785076	3	+	27260156	NCIH2009	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.14281970149666545	[325]	[564,360,341]	-2	hSpCas9	negative selection	7908991
186784621	186784644	3	+	27260156	NCIH2009	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.05278735874009019	[574]	[744,628,944]	0	hSpCas9	negative selection	7908992
186784445	186784468	3	+	27260156	NCIH2009	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.5195869698484046	[595]	[895,410,499]	-6	hSpCas9	negative selection	7908993
186785059	186785082	3	-	27260156	NCIH1373	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.41818045515964064	[667]	[851,1139,671,346]	4	hSpCas9	negative selection	7965976
186784620	186784643	3	-	27260156	NCIH1373	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.005045457632530503	[757]	[1001,525,739,320]	0	hSpCas9	negative selection	7965977
186784461	186784484	3	-	27260156	NCIH1373	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.1380225177005887	[1454]	[2189,958,1381,410]	-1	hSpCas9	negative selection	7965978
186785053	186785076	3	+	27260156	NCIH1373	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.4023460983464088	[325]	[318,271,162,95]	-4	hSpCas9	negative selection	8030242
186784621	186784644	3	+	27260156	NCIH1373	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.267094775933278	[574]	[748,778,697,229]	2	hSpCas9	negative selection	8030243
186784445	186784468	3	+	27260156	NCIH1373	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-1.0132288539262906	[595]	[296,407,213,103]	-8	hSpCas9	negative selection	8030244
186785059	186785082	3	-	27260156	PATU8902	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.29689138840002627	[667]	[1456,1091,911,1158]	3	hSpCas9	negative selection	8087227
186784620	186784643	3	-	27260156	PATU8902	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.29233328052277013	[757]	[795,890,688,1144]	-3	hSpCas9	negative selection	8087228
186784461	186784484	3	-	27260156	PATU8902	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.33564687772089963	[1454]	[1464,1447,1738,1740]	-3	hSpCas9	negative selection	8087229
186785053	186785076	3	+	27260156	PATU8902	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.5801604224553181	[325]	[558,151,174,362]	-5	hSpCas9	negative selection	8151493
186784621	186784644	3	+	27260156	PATU8902	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.5319821012761188	[574]	[953,1049,1092,1596]	5	hSpCas9	negative selection	8151494
186784445	186784468	3	+	27260156	PATU8902	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-2.3414972987586564	[595]	[241,216,81,128]	-9	hSpCas9	negative selection	8151495
186785059	186785082	3	-	27260156	PANC1	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.25102349328696405	[667]	[501,874,912,504]	4	hSpCas9	negative selection	8208478
186784620	186784643	3	-	27260156	PANC1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.17044872422504587	[757]	[554,566,769,435]	-3	hSpCas9	negative selection	8208479
186784461	186784484	3	-	27260156	PANC1	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.12450454711857484	[1454]	[1235,1676,1384,1219]	2	hSpCas9	negative selection	8208480
186785053	186785076	3	+	27260156	PANC1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.24123336341523915	[325]	[236,239,268,203]	-4	hSpCas9	negative selection	8272744
186784621	186784644	3	+	27260156	PANC1	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.03581764114810876	[574]	[370,768,532,415]	0	hSpCas9	negative selection	8272745
186784445	186784468	3	+	27260156	PANC1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.5798209857972285	[595]	[332,458,387,227]	-7	hSpCas9	negative selection	8272746
186785059	186785082	3	-	27260156	PANC0813	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.4565365856827778	[667]	[1184,972,989,1161]	7	hSpCas9	negative selection	8329729
186784620	186784643	3	-	27260156	PANC0813	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.41631921230748337	[757]	[1426,1025,1288,1039]	6	hSpCas9	negative selection	8329730
186784461	186784484	3	-	27260156	PANC0813	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.20344464253223915	[1454]	[1685,1389,1271,1597]	-3	hSpCas9	negative selection	8329731
186785053	186785076	3	+	27260156	PANC0813	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.357108840063337	[325]	[395,292,216,297]	-5	hSpCas9	negative selection	8393995
186784621	186784644	3	+	27260156	PANC0813	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.27306110067281186	[574]	[922,1134,689,539]	4	hSpCas9	negative selection	8393996
186784445	186784468	3	+	27260156	PANC0813	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.83213803426178	[595]	[474,350,433,323]	-8	hSpCas9	negative selection	8393997
186785059	186785082	3	-	27260156	RDES	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.4594353683212137	[667]	[964,898,1249,1130]	7	hSpCas9	negative selection	8450980
186784620	186784643	3	-	27260156	RDES	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.10491846000817429	[757]	[654,894,657,1067]	-2	hSpCas9	negative selection	8450981
186784461	186784484	3	-	27260156	RDES	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.22537113399032127	[1454]	[1654,1605,2018,2700]	3	hSpCas9	negative selection	8450982
186785053	186785076	3	+	27260156	RDES	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.1616522259406905	[325]	[274,290,320,482]	-3	hSpCas9	negative selection	8515246
186784621	186784644	3	+	27260156	RDES	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.3676427139953311	[574]	[785,766,850,1030]	6	hSpCas9	negative selection	8515247
186784445	186784468	3	+	27260156	RDES	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.6382779651371624	[595]	[305,391,455,663]	-8	hSpCas9	negative selection	8515248
186785059	186785082	3	-	27260156	PC3	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.12680104531159786	[667]	[406,583,1530,787]	3	hSpCas9	negative selection	8572231
186784620	186784643	3	-	27260156	PC3	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.14667928904832117	[757]	[451,596,1155,748]	-3	hSpCas9	negative selection	8572232
186784461	186784484	3	-	27260156	PC3	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.12471310872821828	[1454]	[1062,1361,2779,1667]	3	hSpCas9	negative selection	8572233
186785053	186785076	3	+	27260156	PC3	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.1275779234886829	[325]	[162,367,620,431]	3	hSpCas9	negative selection	8636497
186784621	186784644	3	+	27260156	PC3	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.10306895563504875	[574]	[372,627,916,712]	2	hSpCas9	negative selection	8636498
186784445	186784468	3	+	27260156	PC3	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.4486054940105681	[595]	[266,422,692,493]	-8	hSpCas9	negative selection	8636499
186785059	186785082	3	-	27260156	PATU8988T	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.08108074390448328	[667]	[547,729,638,830]	1	hSpCas9	negative selection	8693482
186784620	186784643	3	-	27260156	PATU8988T	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.21197188149251334	[757]	[563,762,1208,843]	3	hSpCas9	negative selection	8693483
186784461	186784484	3	-	27260156	PATU8988T	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.17336977652648944	[1454]	[1540,1575,1520,1713]	3	hSpCas9	negative selection	8693484
186785053	186785076	3	+	27260156	PATU8988T	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.04710280546663931	[325]	[430,220,384,247]	0	hSpCas9	negative selection	8757748
186784621	186784644	3	+	27260156	PATU8988T	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.3040210628898031	[574]	[398,402,311,703]	-5	hSpCas9	negative selection	8757749
186784445	186784468	3	+	27260156	PATU8988T	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.11354754722984	[595]	[463,721,550,398]	-2	hSpCas9	negative selection	8757750
186785059	186785082	3	-	27260156	T47D	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.32058715622329503	[667]	[938,794,1129,1037]	6	hSpCas9	negative selection	8814733
186784620	186784643	3	-	27260156	T47D	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.10104968417890847	[757]	[862,815,777,837]	-2	hSpCas9	negative selection	8814734
186784461	186784484	3	-	27260156	T47D	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.33008004025586457	[1454]	[1296,1452,1281,1352]	-6	hSpCas9	negative selection	8814735
186785053	186785076	3	+	27260156	T47D	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.2924920410324753	[325]	[341,253,314,334]	-6	hSpCas9	negative selection	8878999
186784621	186784644	3	+	27260156	T47D	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.016913388161713727	[574]	[651,579,608,819]	0	hSpCas9	negative selection	8879000
186784445	186784468	3	+	27260156	T47D	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.5707090127147632	[595]	[487,452,486,441]	-8	hSpCas9	negative selection	8879001
186785059	186785082	3	-	27260156	SU8686	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.38388669047081714	[667]	[878,769,807,1028]	6	hSpCas9	negative selection	8935984
186784620	186784643	3	-	27260156	SU8686	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.06417690207574778	[757]	[477,739,906,1108]	1	hSpCas9	negative selection	8935985
186784461	186784484	3	-	27260156	SU8686	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.19847216857824534	[1454]	[1167,1079,1447,1381]	-3	hSpCas9	negative selection	8935986
186785053	186785076	3	+	27260156	SU8686	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.1845493138466655	[325]	[245,314,431,520]	3	hSpCas9	negative selection	9000250
186784621	186784644	3	+	27260156	SU8686	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.18863721944535583	[574]	[747,512,607,745]	3	hSpCas9	negative selection	9000251
186784445	186784468	3	+	27260156	SU8686	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.28410084993220225	[595]	[263,591,519,590]	-5	hSpCas9	negative selection	9000252
186785059	186785082	3	-	27260156	SKES1	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.30360036498132814	[667]	[1143,1056,655,533]	6	hSpCas9	negative selection	9057235
186784620	186784643	3	-	27260156	SKES1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.35016118785469147	[757]	[564,698,599,519]	-6	hSpCas9	negative selection	9057236
186784461	186784484	3	-	27260156	SKES1	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.1445989137136543	[1454]	[1356,1913,1419,1702]	3	hSpCas9	negative selection	9057237
186785053	186785076	3	+	27260156	SKES1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.08879098864869228	[325]	[290,290,392,246]	-2	hSpCas9	negative selection	9121501
186784621	186784644	3	+	27260156	SKES1	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	-0.03770152857761544	[574]	[732,591,481,462]	-1	hSpCas9	negative selection	9121502
186784445	186784468	3	+	27260156	SKES1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.5231161318045682	[595]	[519,360,421,361]	-8	hSpCas9	negative selection	9121503
186785059	186785082	3	-	27260156	TOV112D	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.3282643057441743	[667]	[850,1013,723,813]	6	hSpCas9	negative selection	9178486
186784620	186784643	3	-	27260156	TOV112D	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.09634559846101864	[757]	[624,900,709,644]	-2	hSpCas9	negative selection	9178487
186784461	186784484	3	-	27260156	TOV112D	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.3552556653091614	[1454]	[1783,2581,1596,1665]	6	hSpCas9	negative selection	9178488
186785053	186785076	3	+	27260156	TOV112D	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.0759697083971328	[325]	[320,391,368,304]	1	hSpCas9	negative selection	9242752
186784621	186784644	3	+	27260156	TOV112D	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.4015875914805148	[574]	[866,859,585,761]	7	hSpCas9	negative selection	9242753
186784445	186784468	3	+	27260156	TOV112D	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.51903281971389	[595]	[369,531,442,346]	-8	hSpCas9	negative selection	9242754
186785059	186785082	3	-	27260156	TC71	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.10821905684728417	[667]	[701,763,781,844]	2	hSpCas9	negative selection	9299737
186784620	186784643	3	-	27260156	TC71	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.11577522794547468	[757]	[736,679,820,759]	-3	hSpCas9	negative selection	9299738
186784461	186784484	3	-	27260156	TC71	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	0.31220559689765337	[1454]	[1702,1988,2077,1978]	7	hSpCas9	negative selection	9299739
186785053	186785076	3	+	27260156	TC71	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.14430544773076642	[325]	[341,417,402,381]	3	hSpCas9	negative selection	9364003
186784621	186784644	3	+	27260156	TC71	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.018473034811971323	[574]	[670,618,587,618]	0	hSpCas9	negative selection	9364004
186784445	186784468	3	+	27260156	TC71	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.08840885698017853	[595]	[559,526,670,646]	-2	hSpCas9	negative selection	9364005
186785059	186785082	3	-	27260156	TC32	viability	TGGGGGCCAATACTAGTGCTTGG	EIF4A2	ENSG00000156976	0.30657056507224434	[667]	[762,515,1055,879]	5	hSpCas9	negative selection	9420988
186784620	186784643	3	-	27260156	TC32	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.13871487917026792	[757]	[621,449,939,667]	-2	hSpCas9	negative selection	9420989
186784461	186784484	3	-	27260156	TC32	viability	TCTTACCTCGATGACACCATCGG	EIF4A2	ENSG00000156976	-0.013366862636547072	[1454]	[1142,1196,1709,1437]	0	hSpCas9	negative selection	9420990
186785053	186785076	3	+	27260156	TC32	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.057610626111227026	[325]	[184,231,415,391]	-1	hSpCas9	negative selection	9485254
186784621	186784644	3	+	27260156	TC32	viability	CTTCGTGGCATCTATGCTTACGG	EIF4A2	ENSG00000156976	0.11175109839476366	[574]	[661,334,735,684]	2	hSpCas9	negative selection	9485255
186784445	186784468	3	+	27260156	TC32	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.8819682525746679	[595]	[294,326,258,297]	-9	hSpCas9	negative selection	9485256
186784620	186784643	3	-	27869803	HPAFII	viability after 27 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.5216511568346283	[598]	[118,302,NaN]	-4	hSpCas9	negative selection	9583937
186784620	186784643	3	-	27869803	HPAFII	viability after 15 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.22577846258626155	[598]	[412,635,NaN]	-3	hSpCas9	negative selection	9666386
186784620	186784643	3	-	27869803	ASPC1	viability after 36 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.024281095248743334	[1343]	[832,488,212]	0	hSpCas9	negative selection	9748835
186784620	186784643	3	-	27869803	PATU8988S	viability after 35 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.21091967708149106	[1041]	[399,324,NaN]	-2	hSpCas9	negative selection	9831284
186784620	186784643	3	-	27869803	PATU8988S	viability after 31 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.11462166045648081	[1041]	[488,399,NaN]	1	hSpCas9	negative selection	9913733
186784620	186784643	3	-	27869803	HPAFII	viability after 35 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.2149545632040044	[598]	[82,461,NaN]	-1	hSpCas9	negative selection	9996182
186784620	186784643	3	-	27869803	HPAFII	viability after 31 days	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.524394790756423	[598]	[126,349,NaN]	-4	hSpCas9	negative selection	10078631
186784445	186784468	3	+	28162770	P31FUJ	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.20838758272043378	[122]	[166]	2	hSpCas9	negative selection	10149109
186785870	186785893	3	+	28162770	P31FUJ	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9907038372327778	[184]	[431]	9	hSpCas9	negative selection	10149110
186784620	186784643	3	-	28162770	P31FUJ	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	1.089125890472984	[55]	[139]	9	hSpCas9	negative selection	10149111
186786199	186786222	3	+	28162770	P31FUJ	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.027982412525880296	[58]	[67]	0	hSpCas9	negative selection	10149112
186784421	186784444	3	+	28162770	P31FUJ	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.5604775324315026	[205]	[356]	6	hSpCas9	negative selection	10149113
186783624	186783647	3	-	28162770	P31FUJ	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.13587965917272582	[758]	[979]	1	hSpCas9	negative selection	10149114
186784456	186784479	3	+	28162770	P31FUJ	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.4464876788549306	[147]	[236]	5	hSpCas9	negative selection	10149115
186785053	186785076	3	+	28162770	P31FUJ	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.04959752628634628	[295]	[359]	0	hSpCas9	negative selection	10149116
186785995	186786018	3	+	28162770	P31FUJ	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.2648274217283779	[924]	[1305]	3	hSpCas9	negative selection	10149117
186786012	186786035	3	-	28162770	P31FUJ	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.27964779652240956	[475]	[678]	3	hSpCas9	negative selection	10149118
186784445	186784468	3	+	28162770	TF1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10318475
186785870	186785893	3	+	28162770	TF1	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10318476
186784620	186784643	3	-	28162770	TF1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10318477
186786199	186786222	3	+	28162770	TF1	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10318478
186784421	186784444	3	+	28162770	TF1	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10318479
186783624	186783647	3	-	28162770	TF1	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[302]	1	hSpCas9	negative selection	10318480
186784456	186784479	3	+	28162770	TF1	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10318481
186785053	186785076	3	+	28162770	TF1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10318482
186785995	186786018	3	+	28162770	TF1	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[369]	1	hSpCas9	negative selection	10318483
186786012	186786035	3	-	28162770	TF1	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10318484
186784445	186784468	3	+	28162770	SKM1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.35249603321013107	[34]	[78]	3	hSpCas9	negative selection	10487841
186785870	186785893	3	+	28162770	SKM1	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9360255116720304	[33]	[114]	8	hSpCas9	negative selection	10487842
186784620	186784643	3	-	28162770	SKM1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-1.3074285251922473	[27]	[19]	-7	hSpCas9	negative selection	10487843
186786199	186786222	3	+	28162770	SKM1	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.03350580321571739	[21]	[37]	0	hSpCas9	negative selection	10487844
186784421	186784444	3	+	28162770	SKM1	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.5405683813627027	[41]	[107]	5	hSpCas9	negative selection	10487845
186783624	186783647	3	-	28162770	SKM1	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.5995617350248486	[192]	[516]	6	hSpCas9	negative selection	10487846
186784456	186784479	3	+	28162770	SKM1	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-1.179553702640089	[40]	[31]	-7	hSpCas9	negative selection	10487847
186785053	186785076	3	+	28162770	SKM1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.3449545364677368	[73]	[102]	-3	hSpCas9	negative selection	10487848
186785995	186786018	3	+	28162770	SKM1	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.0682779347415976	[197]	[366]	0	hSpCas9	negative selection	10487849
186786012	186786035	3	-	28162770	SKM1	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.4461944129275671	[92]	[223]	4	hSpCas9	negative selection	10487850
186784445	186784468	3	+	28162770	SKM1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.35249603321013107	[34]	[78]	3	hSpCas9	negative selection	10657207
186785870	186785893	3	+	28162770	SKM1	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9360255116720304	[33]	[114]	8	hSpCas9	negative selection	10657208
186784620	186784643	3	-	28162770	SKM1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-1.3074285251922473	[27]	[19]	-7	hSpCas9	negative selection	10657209
186786199	186786222	3	+	28162770	SKM1	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.03350580321571739	[21]	[37]	0	hSpCas9	negative selection	10657210
186784421	186784444	3	+	28162770	SKM1	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.5405683813627027	[41]	[107]	5	hSpCas9	negative selection	10657211
186783624	186783647	3	-	28162770	SKM1	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.5995617350248486	[192]	[516]	6	hSpCas9	negative selection	10657212
186784456	186784479	3	+	28162770	SKM1	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-1.179553702640089	[40]	[31]	-7	hSpCas9	negative selection	10657213
186785053	186785076	3	+	28162770	SKM1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.3449545364677368	[73]	[102]	-3	hSpCas9	negative selection	10657214
186785995	186786018	3	+	28162770	SKM1	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.0682779347415976	[197]	[366]	0	hSpCas9	negative selection	10657215
186786012	186786035	3	-	28162770	SKM1	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.4461944129275671	[92]	[223]	4	hSpCas9	negative selection	10657216
186784445	186784468	3	+	28162770	PL21	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-1.0222528068471277	[139]	[29]	-6	hSpCas9	negative selection	10826573
186785870	186785893	3	+	28162770	PL21	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.8249280957036645	[130]	[100]	7	hSpCas9	negative selection	10826574
186784620	186784643	3	-	28162770	PL21	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.3404287668733825	[63]	[21]	-2	hSpCas9	negative selection	10826575
186786199	186786222	3	+	28162770	PL21	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.9245051718758928	[114]	[94]	7	hSpCas9	negative selection	10826576
186784421	186784444	3	+	28162770	PL21	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.2292859601488366	[146]	[74]	2	hSpCas9	negative selection	10826577
186783624	186783647	3	-	28162770	PL21	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.2200391719270247	[719]	[364]	2	hSpCas9	negative selection	10826578
186784456	186784479	3	+	28162770	PL21	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.4951464100613939	[118]	[72]	4	hSpCas9	negative selection	10826579
186785053	186785076	3	+	28162770	PL21	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.3055004335704304	[229]	[80]	-2	hSpCas9	negative selection	10826580
186785995	186786018	3	+	28162770	PL21	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.8560380220214214	[753]	[593]	7	hSpCas9	negative selection	10826581
186786012	186786035	3	-	28162770	PL21	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.5356747627287102	[400]	[252]	5	hSpCas9	negative selection	10826582
186784445	186784468	3	+	28162770	P31FUJ	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.20838758272043378	[122]	[166]	2	hSpCas9	negative selection	10995939
186785870	186785893	3	+	28162770	P31FUJ	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9907038372327778	[184]	[431]	9	hSpCas9	negative selection	10995940
186784620	186784643	3	-	28162770	P31FUJ	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	1.089125890472984	[55]	[139]	9	hSpCas9	negative selection	10995941
186786199	186786222	3	+	28162770	P31FUJ	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.027982412525880296	[58]	[67]	0	hSpCas9	negative selection	10995942
186784421	186784444	3	+	28162770	P31FUJ	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.5604775324315026	[205]	[356]	6	hSpCas9	negative selection	10995943
186783624	186783647	3	-	28162770	P31FUJ	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.13587965917272582	[758]	[979]	1	hSpCas9	negative selection	10995944
186784456	186784479	3	+	28162770	P31FUJ	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.4464876788549306	[147]	[236]	5	hSpCas9	negative selection	10995945
186785053	186785076	3	+	28162770	P31FUJ	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.04959752628634628	[295]	[359]	0	hSpCas9	negative selection	10995946
186785995	186786018	3	+	28162770	P31FUJ	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.2648274217283779	[924]	[1305]	3	hSpCas9	negative selection	10995947
186786012	186786035	3	-	28162770	P31FUJ	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.27964779652240956	[475]	[678]	3	hSpCas9	negative selection	10995948
186784445	186784468	3	+	28162770	OCIAML5	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.5231180482988625	[81]	[102]	-4	hSpCas9	negative selection	11165305
186785870	186785893	3	+	28162770	OCIAML5	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.40650818677909684	[134]	[322]	3	hSpCas9	negative selection	11165306
186784620	186784643	3	-	28162770	OCIAML5	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.410062023984884	[52]	[71]	-3	hSpCas9	negative selection	11165307
186786199	186786222	3	+	28162770	OCIAML5	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.12890677622282143	[62]	[103]	-1	hSpCas9	negative selection	11165308
186784421	186784444	3	+	28162770	OCIAML5	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.4746994895512082	[96]	[125]	-3	hSpCas9	negative selection	11165309
186783624	186783647	3	-	28162770	OCIAML5	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.24974252847786982	[464]	[997]	2	hSpCas9	negative selection	11165310
186784456	186784479	3	+	28162770	OCIAML5	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.331533367475392	[69]	[158]	3	hSpCas9	negative selection	11165311
186785053	186785076	3	+	28162770	OCIAML5	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.24800038423992554	[180]	[387]	2	hSpCas9	negative selection	11165312
186785995	186786018	3	+	28162770	OCIAML5	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.4202594378236193	[502]	[1214]	3	hSpCas9	negative selection	11165313
186786012	186786035	3	-	28162770	OCIAML5	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.08061716099743976	[339]	[648]	0	hSpCas9	negative selection	11165314
186784445	186784468	3	+	28162770	EOL1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	1.0695428382303918	[226]	[250]	8	hSpCas9	negative selection	11334671
186785870	186785893	3	+	28162770	EOL1	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.5722460276396535	[179]	[140]	5	hSpCas9	negative selection	11334672
186784620	186784643	3	-	28162770	EOL1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.6393531136227921	[135]	[45]	-4	hSpCas9	negative selection	11334673
186786199	186786222	3	+	28162770	EOL1	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.0765508650155845	[179]	[99]	0	hSpCas9	negative selection	11334674
186784421	186784444	3	+	28162770	EOL1	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-1.2269399816151014	[310]	[69]	-7	hSpCas9	negative selection	11334675
186783624	186783647	3	-	28162770	EOL1	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.18532972567294959	[1281]	[767]	1	hSpCas9	negative selection	11334676
186784456	186784479	3	+	28162770	EOL1	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.011259404763865444	[112]	[59]	0	hSpCas9	negative selection	11334677
186785053	186785076	3	+	28162770	EOL1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	1.1447223676571638	[278]	[324]	8	hSpCas9	negative selection	11334678
186785995	186786018	3	+	28162770	EOL1	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.17338386120135252	[918]	[545]	1	hSpCas9	negative selection	11334679
186786012	186786035	3	-	28162770	EOL1	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.11575231515371553	[500]	[285]	1	hSpCas9	negative selection	11334680
186784445	186784468	3	+	28162770	MOLM13	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.3127703148776727	[205]	[184]	2	hSpCas9	negative selection	11504037
186785870	186785893	3	+	28162770	MOLM13	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9616102305159011	[222]	[313]	7	hSpCas9	negative selection	11504038
186784620	186784643	3	-	28162770	MOLM13	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	2.1654807373766407	[77]	[252]	9	hSpCas9	negative selection	11504039
186786199	186786222	3	+	28162770	MOLM13	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.390934555494727	[106]	[58]	-2	hSpCas9	negative selection	11504040
186784421	186784444	3	+	28162770	MOLM13	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.45534412822546516	[230]	[228]	3	hSpCas9	negative selection	11504041
186783624	186783647	3	-	28162770	MOLM13	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.49334496222724855	[954]	[971]	3	hSpCas9	negative selection	11504042
186784456	186784479	3	+	28162770	MOLM13	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-1.532110618455421	[155]	[38]	-6	hSpCas9	negative selection	11504043
186785053	186785076	3	+	28162770	MOLM13	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.6291234227228466	[295]	[330]	5	hSpCas9	negative selection	11504044
186785995	186786018	3	+	28162770	MOLM13	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.29439822909282687	[961]	[852]	2	hSpCas9	negative selection	11504045
186786012	186786035	3	-	28162770	MOLM13	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-1.2716780078099073	[924]	[276]	-6	hSpCas9	negative selection	11504046
186784445	186784468	3	+	28162770	HEL	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.30176605540793944	[203]	[105]	-2	hSpCas9	negative selection	11673403
186785870	186785893	3	+	28162770	HEL	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.5091556776217651	[146]	[133]	4	hSpCas9	negative selection	11673404
186784620	186784643	3	-	28162770	HEL	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-1.3207352919745292	[77]	[19]	-6	hSpCas9	negative selection	11673405
186786199	186786222	3	+	28162770	HEL	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.37355219918496785	[93]	[77]	3	hSpCas9	negative selection	11673406
186784421	186784444	3	+	28162770	HEL	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.8682230872770224	[227]	[79]	-5	hSpCas9	negative selection	11673407
186783624	186783647	3	-	28162770	HEL	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	-0.1250877258706098	[944]	[554]	-1	hSpCas9	negative selection	11673408
186784456	186784479	3	+	28162770	HEL	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	-0.009337864579336275	[87]	[55]	0	hSpCas9	negative selection	11673409
186785053	186785076	3	+	28162770	HEL	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.1782716234657615	[286]	[207]	1	hSpCas9	negative selection	11673410
186785995	186786018	3	+	28162770	HEL	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.43395392499412755	[733]	[347]	-3	hSpCas9	negative selection	11673411
186786012	186786035	3	-	28162770	HEL	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-1.280184944981002	[655]	[172]	-6	hSpCas9	negative selection	11673412
186784445	186784468	3	+	28162770	MV411	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-1.0200427600822106	[129]	[53]	-6	hSpCas9	negative selection	11842769
186785870	186785893	3	+	28162770	MV411	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	1.4698299721192232	[86]	[202]	9	hSpCas9	negative selection	11842770
186784620	186784643	3	-	28162770	MV411	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.4499304146815185	[72]	[83]	4	hSpCas9	negative selection	11842771
186786199	186786222	3	+	28162770	MV411	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.9181299255298152	[97]	[155]	8	hSpCas9	negative selection	11842772
186784421	186784444	3	+	28162770	MV411	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-1.0941193508535196	[184]	[72]	-6	hSpCas9	negative selection	11842773
186783624	186783647	3	-	28162770	MV411	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.24940441549217618	[732]	[733]	2	hSpCas9	negative selection	11842774
186784456	186784479	3	+	28162770	MV411	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.49465525115379416	[106]	[126]	4	hSpCas9	negative selection	11842775
186785053	186785076	3	+	28162770	MV411	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.14779146741588833	[216]	[164]	-1	hSpCas9	negative selection	11842776
186785995	186786018	3	+	28162770	MV411	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.5922838809564528	[636]	[808]	5	hSpCas9	negative selection	11842777
186786012	186786035	3	-	28162770	MV411	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	0.22277549654850592	[353]	[347]	2	hSpCas9	negative selection	11842778
186784445	186784468	3	+	28162770	MONOMAC1	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.012004953227032933	[94]	[107]	0	hSpCas9	negative selection	12012135
186785870	186785893	3	+	28162770	MONOMAC1	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.9780498594985376	[61]	[139]	8	hSpCas9	negative selection	12012136
186784620	186784643	3	-	28162770	MONOMAC1	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	0.04175001252756294	[49]	[58]	0	hSpCas9	negative selection	12012137
186786199	186786222	3	+	28162770	MONOMAC1	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	0.39664287076271143	[54]	[82]	4	hSpCas9	negative selection	12012138
186784421	186784444	3	+	28162770	MONOMAC1	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	0.1192224977411166	[101]	[126]	1	hSpCas9	negative selection	12012139
186783624	186783647	3	-	28162770	MONOMAC1	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.31650791058523575	[420]	[600]	3	hSpCas9	negative selection	12012140
186784456	186784479	3	+	28162770	MONOMAC1	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.442787588696121	[42]	[66]	4	hSpCas9	negative selection	12012141
186785053	186785076	3	+	28162770	MONOMAC1	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.27327243288663905	[135]	[128]	-2	hSpCas9	negative selection	12012142
186785995	186786018	3	+	28162770	MONOMAC1	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.0945343077107621	[420]	[451]	-1	hSpCas9	negative selection	12012143
186786012	186786035	3	-	28162770	MONOMAC1	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.1970368470595536	[180]	[180]	-2	hSpCas9	negative selection	12012144
186784445	186784468	3	+	28162770	OCIAML2	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	-0.20966974764622598	[28]	[138]	-2	hSpCas9	negative selection	12181501
186785870	186785893	3	+	28162770	OCIAML2	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.3586398732438833	[27]	[198]	3	hSpCas9	negative selection	12181502
186784620	186784643	3	-	28162770	OCIAML2	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.2884264940214123	[12]	[58]	-2	hSpCas9	negative selection	12181503
186786199	186786222	3	+	28162770	OCIAML2	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	-0.5320303699063045	[29]	[114]	-4	hSpCas9	negative selection	12181504
186784421	186784444	3	+	28162770	OCIAML2	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.3214038164676849	[38]	[172]	-3	hSpCas9	negative selection	12181505
186783624	186783647	3	-	28162770	OCIAML2	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.4883983937015324	[124]	[971]	5	hSpCas9	negative selection	12181506
186784456	186784479	3	+	28162770	OCIAML2	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.06542307499804867	[14]	[86]	0	hSpCas9	negative selection	12181507
186785053	186785076	3	+	28162770	OCIAML2	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	0.24361569242396136	[31]	[209]	2	hSpCas9	negative selection	12181508
186785995	186786018	3	+	28162770	OCIAML2	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	-0.4219037854257399	[130]	[541]	-3	hSpCas9	negative selection	12181509
186786012	186786035	3	-	28162770	OCIAML2	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.28541495277525375	[72]	[331]	-2	hSpCas9	negative selection	12181510
186784445	186784468	3	+	28162770	OCIAML3	viability	CCAGAGGGAATGGACCCCGATGG	EIF4A2	ENSG00000156976	0.6499179425619261	[37]	[179]	6	hSpCas9	negative selection	12350867
186785870	186785893	3	+	28162770	OCIAML3	viability	GCTTGGGTTTTAGATCCAAAAGG	EIF4A2	ENSG00000156976	0.18560229125053682	[59]	[205]	1	hSpCas9	negative selection	12350868
186784620	186784643	3	-	28162770	OCIAML3	viability	CGTAAGCATAGATGCCACGAAGG	EIF4A2	ENSG00000156976	-0.09150729979497996	[17]	[50]	0	hSpCas9	negative selection	12350869
186786199	186786222	3	+	28162770	OCIAML3	viability	GCAGATGAAATGTTGAGCCGTGG	EIF4A2	ENSG00000156976	1.710846941204258	[16]	[167]	9	hSpCas9	negative selection	12350870
186784421	186784444	3	+	28162770	OCIAML3	viability	CTTGTCAGCAGAGAACATGGCGG	EIF4A2	ENSG00000156976	-0.2785058145962339	[44]	[111]	-2	hSpCas9	negative selection	12350871
186783624	186783647	3	-	28162770	OCIAML3	viability	TGCATACCTGTTATAATCCGCGG	EIF4A2	ENSG00000156976	0.37486984218005626	[163]	[641]	3	hSpCas9	negative selection	12350872
186784456	186784479	3	+	28162770	OCIAML3	viability	GGACCCCGATGGTGTCATCGAGG	EIF4A2	ENSG00000156976	0.16087986183930525	[23]	[80]	1	hSpCas9	negative selection	12350873
186785053	186785076	3	+	28162770	OCIAML3	viability	GGAGACCCAAGCACTAGTATTGG	EIF4A2	ENSG00000156976	-0.25415763743953845	[63]	[161]	-2	hSpCas9	negative selection	12350874
186785995	186786018	3	+	28162770	OCIAML3	viability	ATATTGTTGTTGGTACACCCGGG	EIF4A2	ENSG00000156976	0.9282992525472253	[199]	[1148]	7	hSpCas9	negative selection	12350875
186786012	186786035	3	-	28162770	OCIAML3	viability	AACATATCAAACACTCTCCCGGG	EIF4A2	ENSG00000156976	-0.25840460853972425	[104]	[264]	-2	hSpCas9	negative selection	12350876