Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2033
• Symbol: EP300
• Description: EP300 lysine acetyltransferase

DataSource: http://genomecrispr.dkfz.de/#!/results/EP300

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41150076	41150099	22	-	26472758	Jiyoye	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-2.141261243190169	[233]	[39]	-8	hSpCas9	negative selection	50728
41150169	41150192	22	-	26472758	Jiyoye	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.89660536667123	[78]	[15]	-8	hSpCas9	negative selection	50729
41117243	41117266	22	+	26472758	Jiyoye	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-1.98277113681014	[151]	[28]	-8	hSpCas9	negative selection	50730
41117485	41117508	22	+	26472758	Jiyoye	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-1.2831401193615117	[425]	[131]	-7	hSpCas9	negative selection	50731
41125918	41125941	22	+	26472758	Jiyoye	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-2.5421985454241587	[223]	[28]	-9	hSpCas9	negative selection	50732
41131539	41131562	22	+	26472758	Jiyoye	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-0.38846611998794023	[275]	[158]	-3	hSpCas9	negative selection	50733
41141059	41141082	22	-	26472758	Jiyoye	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.8953873885145578	[73]	[14]	-8	hSpCas9	negative selection	50734
41149839	41149862	22	-	26472758	Jiyoye	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.44923376486527683	[171]	[94]	-3	hSpCas9	negative selection	50735
41149875	41149898	22	-	26472758	Jiyoye	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.4997152141026453	[179]	[47]	-7	hSpCas9	negative selection	50736
41149959	41149982	22	-	26472758	Jiyoye	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.4811792626652174	[86]	[46]	-3	hSpCas9	negative selection	50737
41150076	41150099	22	-	26472758	KBM7	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.4943032356366568	[1075,979]	[254,96]	-8	hSpCas9	negative selection	241846
41150169	41150192	22	-	26472758	KBM7	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.663940131951941	[787,663]	[25,179]	-8	hSpCas9	negative selection	241847
41117243	41117266	22	+	26472758	KBM7	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-1.0809416125843174	[605,396]	[125,94]	-7	hSpCas9	negative selection	241848
41117485	41117508	22	+	26472758	KBM7	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.3911942255539259	[1348,893]	[410,381]	-4	hSpCas9	negative selection	241849
41125918	41125941	22	+	26472758	KBM7	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.3755772167937546	[737,488]	[63,149]	-7	hSpCas9	negative selection	241850
41131539	41131562	22	+	26472758	KBM7	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-0.21602193881417864	[1496,1135]	[734,342]	-2	hSpCas9	negative selection	241851
41141059	41141082	22	-	26472758	KBM7	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.2107717962270717	[324,315]	[77,53]	-7	hSpCas9	negative selection	241852
41149839	41149862	22	-	26472758	KBM7	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	0.09824476675875476	[677,563]	[364,262]	1	hSpCas9	negative selection	241853
41149875	41149898	22	-	26472758	KBM7	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.3158297785264607	[679,728]	[270,265]	-3	hSpCas9	negative selection	241854
41149959	41149982	22	-	26472758	KBM7	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.9320489116907167	[385,360]	[69,111]	-6	hSpCas9	negative selection	241855
41150076	41150099	22	-	26472758	Raji	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-3.8233538021892866	[365]	[5]	-9	hSpCas9	negative selection	432964
41150169	41150192	22	-	26472758	Raji	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-3.8327832151092176	[306]	[4]	-9	hSpCas9	negative selection	432965
41117243	41117266	22	+	26472758	Raji	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.799507060234919	[329]	[10]	-9	hSpCas9	negative selection	432966
41117485	41117508	22	+	26472758	Raji	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-1.5528670926517938	[530]	[41]	-8	hSpCas9	negative selection	432967
41125918	41125941	22	+	26472758	Raji	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.5763129189329164	[256]	[19]	-8	hSpCas9	negative selection	432968
41131539	41131562	22	+	26472758	Raji	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.3653694617615317	[543]	[48]	-7	hSpCas9	negative selection	432969
41141059	41141082	22	-	26472758	Raji	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-2.805505800856362	[240]	[7]	-9	hSpCas9	negative selection	432970
41149839	41149862	22	-	26472758	Raji	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-2.536472654401125	[424]	[16]	-9	hSpCas9	negative selection	432971
41149875	41149898	22	-	26472758	Raji	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.9679045919306375	[353]	[20]	-8	hSpCas9	negative selection	432972
41149959	41149982	22	-	26472758	Raji	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-1.5026699463103872	[231]	[18]	-8	hSpCas9	negative selection	432973
41150076	41150099	22	-	26472758	K562	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-3.8863356764951877	[980]	[55]	-9	hSpCas9	negative selection	624082
41150169	41150192	22	-	26472758	K562	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-5.134626338019276	[540]	[12]	-9	hSpCas9	negative selection	624083
41117243	41117266	22	+	26472758	K562	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.070783504032602	[427]	[85]	-7	hSpCas9	negative selection	624084
41117485	41117508	22	+	26472758	K562	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-1.446036901902023	[935]	[289]	-6	hSpCas9	negative selection	624085
41125918	41125941	22	+	26472758	K562	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-2.6659027733423453	[420]	[55]	-8	hSpCas9	negative selection	624086
41131539	41131562	22	+	26472758	K562	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-2.1320684660105926	[996]	[191]	-7	hSpCas9	negative selection	624087
41141059	41141082	22	-	26472758	K562	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-5.442081799516772	[308]	[5]	-9	hSpCas9	negative selection	624088
41149839	41149862	22	-	26472758	K562	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-1.5421776342243598	[551]	[159]	-6	hSpCas9	negative selection	624089
41149875	41149898	22	-	26472758	K562	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.2048886736971431	[638]	[233]	-6	hSpCas9	negative selection	624090
41149959	41149982	22	-	26472758	K562	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-2.173893903645258	[293]	[54]	-7	hSpCas9	negative selection	624091
41093069	41093092	22	-	26627737	DLD1	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.0263262161561943	[214]	[5,53,38]	-7	hSpCas9	negative selection	817985
41117390	41117413	22	-	26627737	DLD1	viability	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.42608039880405446	[610]	[160,89,168]	-4	hSpCas9	negative selection	817986
41126017	41126040	22	-	26627737	DLD1	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.21944621419456367	[319]	[122,50,164]	2	hSpCas9	negative selection	817987
41127528	41127551	22	+	26627737	DLD1	viability	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.6746354019902954	[80]	[49,48,24]	6	hSpCas9	negative selection	817988
41131557	41131580	22	-	26627737	DLD1	viability	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.0870935753167873	[270]	[17,131,89]	-1	hSpCas9	negative selection	817989
41137673	41137696	22	-	26627737	DLD1	viability	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-2.5365940564146268	[311]	[33,0,14]	-9	hSpCas9	negative selection	817990
41093069	41093092	22	-	26627737	GBM cells	viability after 5 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.04523289038079725	[75]	[35,42]	0	hSpCas9	negative selection	900300
41117390	41117413	22	-	26627737	GBM cells	viability after 5 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.7580513390458361	[214]	[214,174]	8	hSpCas9	negative selection	900301
41126017	41126040	22	-	26627737	GBM cells	viability after 5 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.17367076574402063	[142]	[91,80]	2	hSpCas9	negative selection	900302
41127528	41127551	22	+	26627737	GBM cells	viability after 5 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-0.7547613759194849	[128]	[44,36]	-8	hSpCas9	negative selection	900303
41131557	41131580	22	-	26627737	GBM cells	viability after 5 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.021397881410680553	[78]	[45,39]	0	hSpCas9	negative selection	900304
41137673	41137696	22	-	26627737	GBM cells	viability after 5 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.42118459748955706	[242]	[149,198]	6	hSpCas9	negative selection	900305
41093069	41093092	22	-	26627737	GBM cells	viability after 13 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.3912410933949868	[75]	[15,43]	-5	hSpCas9	negative selection	982615
41117390	41117413	22	-	26627737	GBM cells	viability after 13 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.8218519522426293	[214]	[278,146]	8	hSpCas9	negative selection	982616
41126017	41126040	22	-	26627737	GBM cells	viability after 13 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.0775828832248702	[142]	[219,117]	9	hSpCas9	negative selection	982617
41127528	41127551	22	+	26627737	GBM cells	viability after 13 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-1.5731816959794724	[128]	[33,14]	-9	hSpCas9	negative selection	982618
41131557	41131580	22	-	26627737	GBM cells	viability after 13 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.40618057993887113	[78]	[33,30]	-5	hSpCas9	negative selection	982619
41137673	41137696	22	-	26627737	GBM cells	viability after 13 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.352761751524621	[242]	[217,127]	4	hSpCas9	negative selection	982620
41093069	41093092	22	-	26627737	GBM cells	viability after 21 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.9798533388308105	[75]	[82,79]	8	hSpCas9	negative selection	1064930
41117390	41117413	22	-	26627737	GBM cells	viability after 21 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.7899344732012056	[214]	[202,200]	7	hSpCas9	negative selection	1064931
41126017	41126040	22	-	26627737	GBM cells	viability after 21 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.533715625516316	[142]	[249,201]	9	hSpCas9	negative selection	1064932
41127528	41127551	22	+	26627737	GBM cells	viability after 21 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-1.6657450105749845	[128]	[19,23]	-8	hSpCas9	negative selection	1064933
41131557	41131580	22	-	26627737	GBM cells	viability after 21 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.3159525633624001	[78]	[34,33]	-3	hSpCas9	negative selection	1064934
41137673	41137696	22	-	26627737	GBM cells	viability after 21 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.686890689216496	[242]	[211,212]	7	hSpCas9	negative selection	1064935
41093069	41093092	22	-	26627737	RPE1	viability after 9 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.0193813131947889	[523]	[76,85]	-6	hSpCas9	negative selection	1147245
41117390	41117413	22	-	26627737	RPE1	viability after 9 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.473199724160448	[1448]	[620,640]	3	hSpCas9	negative selection	1147246
41126017	41126040	22	-	26627737	RPE1	viability after 9 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.4243405731073377	[303]	[161,375]	7	hSpCas9	negative selection	1147247
41127528	41127551	22	+	26627737	RPE1	viability after 9 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.5602262684012937	[368]	[182,153]	4	hSpCas9	negative selection	1147248
41131557	41131580	22	-	26627737	RPE1	viability after 9 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.11507395287952468	[692]	[298,72]	-1	hSpCas9	negative selection	1147249
41137673	41137696	22	-	26627737	RPE1	viability after 9 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.15350861352282164	[1841]	[500,540]	-1	hSpCas9	negative selection	1147250
41093069	41093092	22	-	26627737	RPE1	viability after 12 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.27861122061632654	[523]	[145,196]	2	hSpCas9	negative selection	1229560
41117390	41117413	22	-	26627737	RPE1	viability after 12 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.8147482298241686	[1448]	[812,548]	5	hSpCas9	negative selection	1229561
41126017	41126040	22	-	26627737	RPE1	viability after 12 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.721789938804493	[303]	[248,290]	8	hSpCas9	negative selection	1229562
41127528	41127551	22	+	26627737	RPE1	viability after 12 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.6034860436758273	[368]	[137,163]	4	hSpCas9	negative selection	1229563
41131557	41131580	22	-	26627737	RPE1	viability after 12 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.28376768624026566	[692]	[214,238]	2	hSpCas9	negative selection	1229564
41137673	41137696	22	-	26627737	RPE1	viability after 12 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.3100812838216801	[1841]	[489,302]	-2	hSpCas9	negative selection	1229565
41093069	41093092	22	-	26627737	RPE1	viability after 15 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.29290672215289354	[523]	[119,240]	2	hSpCas9	negative selection	1311875
41117390	41117413	22	-	26627737	RPE1	viability after 15 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	1.318393043000137	[1448]	[1459,599]	7	hSpCas9	negative selection	1311876
41126017	41126040	22	-	26627737	RPE1	viability after 15 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.406181590536154	[303]	[91,358]	7	hSpCas9	negative selection	1311877
41127528	41127551	22	+	26627737	RPE1	viability after 15 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	1.5584703096020072	[368]	[450,168]	8	hSpCas9	negative selection	1311878
41131557	41131580	22	-	26627737	RPE1	viability after 15 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.25396461049251406	[692]	[274,193]	1	hSpCas9	negative selection	1311879
41137673	41137696	22	-	26627737	RPE1	viability after 15 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.2006880486409397	[1841]	[599,311]	-1	hSpCas9	negative selection	1311880
41093069	41093092	22	-	26627737	RPE1	viability after 18 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.8132234784030754	[523]	[174,326]	5	hSpCas9	negative selection	1394190
41117390	41117413	22	-	26627737	RPE1	viability after 18 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	1.5613427610263073	[1448]	[1534,746]	7	hSpCas9	negative selection	1394191
41126017	41126040	22	-	26627737	RPE1	viability after 18 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	2.363082951054093	[303]	[394,450]	9	hSpCas9	negative selection	1394192
41127528	41127551	22	+	26627737	RPE1	viability after 18 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	1.6772871464031143	[368]	[390,240]	8	hSpCas9	negative selection	1394193
41131557	41131580	22	-	26627737	RPE1	viability after 18 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.6237124163290578	[692]	[292,282]	4	hSpCas9	negative selection	1394194
41137673	41137696	22	-	26627737	RPE1	viability after 18 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.32320579130215643	[1841]	[677,561]	2	hSpCas9	negative selection	1394195
41093069	41093092	22	-	26627737	HeLa	viability after 8 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.34245495073055476	[163]	[3,91,60]	-3	hSpCas9	negative selection	1476505
41117390	41117413	22	-	26627737	HeLa	viability after 8 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.5658484005775495	[696]	[238,234,151]	-5	hSpCas9	negative selection	1476506
41126017	41126040	22	-	26627737	HeLa	viability after 8 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.8666225215435661	[205]	[280,127,110]	7	hSpCas9	negative selection	1476507
41127528	41127551	22	+	26627737	HeLa	viability after 8 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-0.7169631324568362	[173]	[54,21,61]	-6	hSpCas9	negative selection	1476508
41131557	41131580	22	-	26627737	HeLa	viability after 8 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.07511051637968014	[149]	[147,25,50]	0	hSpCas9	negative selection	1476509
41137673	41137696	22	-	26627737	HeLa	viability after 8 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.27056962170676424	[354]	[145,200,201]	2	hSpCas9	negative selection	1476510
41093069	41093092	22	-	26627737	HeLa	viability after 12 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.4418231832152533	[163]	[42,18,13]	-8	hSpCas9	negative selection	1558820
41117390	41117413	22	-	26627737	HeLa	viability after 12 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-1.4700098759490448	[696]	[64,120,122]	-8	hSpCas9	negative selection	1558821
41126017	41126040	22	-	26627737	HeLa	viability after 12 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.40656420754570877	[205]	[119,100,118]	3	hSpCas9	negative selection	1558822
41127528	41127551	22	+	26627737	HeLa	viability after 12 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.448002501358454	[173]	[165,24,112]	4	hSpCas9	negative selection	1558823
41131557	41131580	22	-	26627737	HeLa	viability after 12 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.122686392509191	[149]	[45,128,227]	7	hSpCas9	negative selection	1558824
41137673	41137696	22	-	26627737	HeLa	viability after 12 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.8980850841343744	[354]	[265,263,290]	7	hSpCas9	negative selection	1558825
41093069	41093092	22	-	26627737	HeLa	viability after 15 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.9110157482575632	[163]	[21,27,1]	-9	hSpCas9	negative selection	1641135
41117390	41117413	22	-	26627737	HeLa	viability after 15 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.013158585140074286	[696]	[338,231,270]	0	hSpCas9	negative selection	1641136
41126017	41126040	22	-	26627737	HeLa	viability after 15 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.020565204131477888	[205]	[141,61,39]	0	hSpCas9	negative selection	1641137
41127528	41127551	22	+	26627737	HeLa	viability after 15 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.6547282091136899	[173]	[171,119,35]	5	hSpCas9	negative selection	1641138
41131557	41131580	22	-	26627737	HeLa	viability after 15 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.9980084787363903	[149]	[76,148,141]	7	hSpCas9	negative selection	1641139
41137673	41137696	22	-	26627737	HeLa	viability after 15 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.48283398518851506	[354]	[54,130,439]	4	hSpCas9	negative selection	1641140
41093069	41093092	22	-	26627737	HeLa	viability after 18 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.8500347726618698	[163]	[13,25,1]	-9	hSpCas9	negative selection	1723450
41117390	41117413	22	-	26627737	HeLa	viability after 18 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.017276133117272163	[696]	[239,190,270]	0	hSpCas9	negative selection	1723451
41126017	41126040	22	-	26627737	HeLa	viability after 18 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.023685838815257654	[205]	[91,54,39]	0	hSpCas9	negative selection	1723452
41127528	41127551	22	+	26627737	HeLa	viability after 18 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.6620461356409693	[173]	[119,94,35]	5	hSpCas9	negative selection	1723453
41131557	41131580	22	-	26627737	HeLa	viability after 18 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.016347157395834	[149]	[50,127,141]	7	hSpCas9	negative selection	1723454
41137673	41137696	22	-	26627737	HeLa	viability after 18 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.4505997378611071	[354]	[34,99,439]	4	hSpCas9	negative selection	1723455
41093069	41093092	22	-	26627737	HCT116	viability after 6 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.6200391804219556	[241]	[36,17]	-4	hSpCas9	negative selection	1805765
41117390	41117413	22	-	26627737	HCT116	viability after 6 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.6930213854652931	[1015]	[691,18]	4	hSpCas9	negative selection	1805766
41126017	41126040	22	-	26627737	HCT116	viability after 6 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.596545706686956	[298]	[29,203]	7	hSpCas9	negative selection	1805767
41127528	41127551	22	+	26627737	HCT116	viability after 6 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-0.24518045892805618	[369]	[128,4]	-1	hSpCas9	negative selection	1805768
41131557	41131580	22	-	26627737	HCT116	viability after 6 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.9991552960065491	[379]	[208,69]	5	hSpCas9	negative selection	1805769
41137673	41137696	22	-	26627737	HCT116	viability after 6 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.6299637685477447	[438]	[100,109]	3	hSpCas9	negative selection	1805770
41093069	41093092	22	-	26627737	HCT116	viability after 8 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-1.0172190234824354	[180]	[46,68,31]	-8	hSpCas9	negative selection	1888080
41117390	41117413	22	-	26627737	HCT116	viability after 8 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.3389137110530063	[462]	[349,333,284]	3	hSpCas9	negative selection	1888081
41126017	41126040	22	-	26627737	HCT116	viability after 8 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.07112837374484149	[211]	[144,136,86]	0	hSpCas9	negative selection	1888082
41127528	41127551	22	+	26627737	HCT116	viability after 8 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.3093387181286329	[112]	[90,86,53]	3	hSpCas9	negative selection	1888083
41131557	41131580	22	-	26627737	HCT116	viability after 8 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.6533490938688367	[58]	[100,121,83]	9	hSpCas9	negative selection	1888084
41137673	41137696	22	-	26627737	HCT116	viability after 8 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.16288840373814	[203]	[250,164,337]	8	hSpCas9	negative selection	1888085
41093069	41093092	22	-	26627737	HCT116	viability after 9 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-3.1590331147539175	[241]	[4,8]	-9	hSpCas9	negative selection	1970395
41117390	41117413	22	-	26627737	HCT116	viability after 9 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.4290544834919523	[1015]	[462,287]	3	hSpCas9	negative selection	1970396
41126017	41126040	22	-	26627737	HCT116	viability after 9 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.2312842807402704	[298]	[186,19]	1	hSpCas9	negative selection	1970397
41127528	41127551	22	+	26627737	HCT116	viability after 9 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.14250794337334916	[369]	[36,165]	1	hSpCas9	negative selection	1970398
41131557	41131580	22	-	26627737	HCT116	viability after 9 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-1.5493885795575433	[379]	[75,1]	-8	hSpCas9	negative selection	1970399
41137673	41137696	22	-	26627737	HCT116	viability after 9 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.3478310635850012	[438]	[71,107]	-2	hSpCas9	negative selection	1970400
41093069	41093092	22	-	26627737	HCT116	viability after 12 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.9567147683650529	[180]	[63,60,20]	-8	hSpCas9	negative selection	2052710
41117390	41117413	22	-	26627737	HCT116	viability after 12 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.5811223971808687	[462]	[369,260,457]	5	hSpCas9	negative selection	2052711
41126017	41126040	22	-	26627737	HCT116	viability after 12 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.3180697225889133	[211]	[113,61,240]	3	hSpCas9	negative selection	2052712
41127528	41127551	22	+	26627737	HCT116	viability after 12 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.3014270596655124	[112]	[55,111,53]	3	hSpCas9	negative selection	2052713
41131557	41131580	22	-	26627737	HCT116	viability after 12 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.480044709366524	[58]	[78,121,59]	9	hSpCas9	negative selection	2052714
41137673	41137696	22	-	26627737	HCT116	viability after 12 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.7809810611693572	[203]	[208,164,175]	7	hSpCas9	negative selection	2052715
41093069	41093092	22	-	26627737	HCT116	viability after 15 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.1553255129727944	[180]	[138,88,57]	-2	hSpCas9	negative selection	2135025
41117390	41117413	22	-	26627737	HCT116	viability after 15 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.8094709694689882	[462]	[477,581,340]	7	hSpCas9	negative selection	2135026
41126017	41126040	22	-	26627737	HCT116	viability after 15 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.22969646738518906	[211]	[183,80,167]	2	hSpCas9	negative selection	2135027
41127528	41127551	22	+	26627737	HCT116	viability after 15 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.307635591774426	[112]	[113,45,84]	3	hSpCas9	negative selection	2135028
41131557	41131580	22	-	26627737	HCT116	viability after 15 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.7547181943690051	[58]	[80,145,111]	9	hSpCas9	negative selection	2135029
41137673	41137696	22	-	26627737	HCT116	viability after 15 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.6254056749843477	[203]	[367,423,293]	9	hSpCas9	negative selection	2135030
41093069	41093092	22	-	26627737	HCT116	viability after 18 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.4072769829306591	[180]	[218,74,53]	3	hSpCas9	negative selection	2217340
41117390	41117413	22	-	26627737	HCT116	viability after 18 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	1.6617855484123543	[462]	[810,697,611]	9	hSpCas9	negative selection	2217341
41126017	41126040	22	-	26627737	HCT116	viability after 18 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.810863664405308	[211]	[257,73,215]	6	hSpCas9	negative selection	2217342
41127528	41127551	22	+	26627737	HCT116	viability after 18 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.7888209829008893	[112]	[98,127,51]	6	hSpCas9	negative selection	2217343
41131557	41131580	22	-	26627737	HCT116	viability after 18 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.9689731592685775	[58]	[137,117,76]	9	hSpCas9	negative selection	2217344
41137673	41137696	22	-	26627737	HCT116	viability after 18 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.7073003234973712	[203]	[384,271,311]	9	hSpCas9	negative selection	2217345
41093007	41093030	22	+	24336569	HL60	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	-1.2569061070387744	[130]	[115]	-8	hSpCas9	negative selection	2262832
41093032	41093055	22	-	24336569	HL60	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	-1.2625982528176019	[855]	[754]	-8	hSpCas9	negative selection	2262833
41093042	41093065	22	-	24336569	HL60	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	-1.0356604110157717	[433]	[447]	-7	hSpCas9	negative selection	2262834
41093050	41093073	22	-	24336569	HL60	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	-0.6143380902015982	[407]	[563]	-5	hSpCas9	negative selection	2262835
41093055	41093078	22	+	24336569	HL60	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	0.008354161619572809	[287]	[612]	0	hSpCas9	negative selection	2262836
41093065	41093088	22	-	24336569	HL60	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	-0.7436159150653855	[738]	[933]	-6	hSpCas9	negative selection	2262837
41093070	41093093	22	-	24336569	HL60	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	-1.1205639203178368	[373]	[363]	-7	hSpCas9	negative selection	2262838
41093077	41093100	22	+	24336569	HL60	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	-1.4823276398829999	[708]	[536]	-8	hSpCas9	negative selection	2262839
41093084	41093107	22	-	24336569	HL60	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-0.5575220378536027	[659]	[948]	-5	hSpCas9	negative selection	2262840
41117222	41117245	22	-	24336569	HL60	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	1.0551408276133896	[218]	[962]	7	hSpCas9	negative selection	2262841
41093007	41093030	22	+	24336569	KBM7	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	-1.3258339241965131	[158]	[172]	-7	hSpCas9	negative selection	2330009
41093032	41093055	22	-	24336569	KBM7	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	-1.314684926051537	[569]	[624]	-7	hSpCas9	negative selection	2330010
41093042	41093065	22	-	24336569	KBM7	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	-0.6918437983628365	[503]	[850]	-5	hSpCas9	negative selection	2330011
41093050	41093073	22	-	24336569	KBM7	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	-1.2086764531879866	[421]	[497]	-7	hSpCas9	negative selection	2330012
41093055	41093078	22	+	24336569	KBM7	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	-0.2776541951065701	[235]	[530]	-2	hSpCas9	negative selection	2330013
41093065	41093088	22	-	24336569	KBM7	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	-1.1225518630026337	[743]	[931]	-7	hSpCas9	negative selection	2330014
41093070	41093093	22	-	24336569	KBM7	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	-1.4795693107933194	[455]	[445]	-7	hSpCas9	negative selection	2330015
41093077	41093100	22	+	24336569	KBM7	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	-1.1092566634108514	[559]	[707]	-7	hSpCas9	negative selection	2330016
41093084	41093107	22	-	24336569	KBM7	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-0.30588111149557107	[561]	[1239]	-3	hSpCas9	negative selection	2330017
41117222	41117245	22	-	24336569	KBM7	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	0.48645754107275896	[178]	[683]	4	hSpCas9	negative selection	2330018
41099318	41099341	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAACAGGCCGGGCGCGGTGG	EP300	ENSG00000100393	-0.0515501815974837	[34,320]	[2,75]	0	dCas9-VP64	positive selection	2390780
41109927	41109950	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCAGGAGGCCGGGG	EP300	ENSG00000100393	1.2848086487689858	[4,11]	[0,7]	5	dCas9-VP64	positive selection	2402909
41112263	41112286	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCTCCCCTGG	EP300	ENSG00000100393	-1.8290271006759882	[291,377]	[12,27]	-8	dCas9-VP64	positive selection	2406501
41101421	41101444	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTTTTTTTGAGACGGAGTCTAG	EP300	ENSG00000100393	-0.0033727294007129816	[93,134]	[41,5]	0	dCas9-VP64	positive selection	2412613
41092409	41092432	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCTCGGGCGAGTTCTCTGCGG	EP300	ENSG00000100393	1.306147620226768	[36,71]	[8,51]	5	dCas9-VP64	positive selection	2427885
41092478	41092501	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGAGGGTTCGGAGGGTGGGGG	EP300	ENSG00000100393	2.693102398770781	[0,0]	[0,0]	8	dCas9-VP64	positive selection	2427886
41092432	41092455	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGCCGCACCGGCCCCTAATGG	EP300	ENSG00000100393	2.09072708597083	[42,83]	[22,98]	7	dCas9-VP64	positive selection	2427887
41099088	41099111	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGTCTTGCTCTGTTGCCCAAG	EP300	ENSG00000100393	-0.819451643023694	[60,30]	[3,6]	-4	dCas9-VP64	positive selection	2435809
41135516	41135539	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCTCAGCACTTCAG	EP300	ENSG00000100393	-0.6796005969874881	[92,259]	[10,38]	-3	dCas9-VP64	positive selection	2447619
41150636	41150659	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTAGCACTTTGGGAGGCTGTGG	EP300	ENSG00000100393	-1.3778645461156502	[16,23]	[1,0]	-7	dCas9-VP64	positive selection	2455524
41167148	41167171	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGAGG	EP300	ENSG00000100393	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473437
41099318	41099341	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAACAGGCCGGGCGCGGTGG	EP300	ENSG00000100393	-0.24132967167370056	[128,18]	[33,7]	-2	dCas9-VP64	positive selection	2486035
41109927	41109950	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCAGGAGGCCGGGG	EP300	ENSG00000100393	-0.42778639369274607	[66,93]	[18,18]	-4	dCas9-VP64	positive selection	2498164
41112263	41112286	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCTCCCCTGG	EP300	ENSG00000100393	0.4396579999349357	[510,531]	[180,277]	3	dCas9-VP64	positive selection	2501756
41101421	41101444	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTTTTTTTGAGACGGAGTCTAG	EP300	ENSG00000100393	-0.5948176551250917	[72,353]	[48,41]	-6	dCas9-VP64	positive selection	2507868
41092409	41092432	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCTCGGGCGAGTTCTCTGCGG	EP300	ENSG00000100393	0.23420909663380018	[36,42]	[21,7]	1	dCas9-VP64	positive selection	2523140
41092478	41092501	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGAGGGTTCGGAGGGTGGGGG	EP300	ENSG00000100393	0.27865309790340387	[9,8]	[2,3]	2	dCas9-VP64	positive selection	2523141
41092432	41092455	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGCCGCACCGGCCCCTAATGG	EP300	ENSG00000100393	-1.650817693725016	[76,610]	[28,39]	-9	dCas9-VP64	positive selection	2523142
41099088	41099111	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGTCTTGCTCTGTTGCCCAAG	EP300	ENSG00000100393	-0.47354638593983023	[115,143]	[24,34]	-5	dCas9-VP64	positive selection	2531064
41135516	41135539	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCTCAGCACTTCAG	EP300	ENSG00000100393	0.2134968510682193	[79,136]	[55,26]	1	dCas9-VP64	positive selection	2542874
41150636	41150659	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTAGCACTTTGGGAGGCTGTGG	EP300	ENSG00000100393	-0.7460689547377737	[92,23]	[17,3]	-7	dCas9-VP64	positive selection	2550779
41167148	41167171	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGAGG	EP300	ENSG00000100393	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568692
41093007	41093030	22	+	27260157	DLD1	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	0.519382876216664	[]	[]	8	hSpCas9	negative selection	2576895
41117246	41117269	22	+	27260157	DLD1	viability	GAATTGGGACTAACCAATGGTGG	EP300	ENSG00000100393	-0.235522147004939	[]	[]	-2	hSpCas9	negative selection	2578515
41093050	41093073	22	-	27260157	DLD1	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	-0.752915672889442	[]	[]	-5	hSpCas9	negative selection	2604565
41093070	41093093	22	-	27260157	DLD1	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	1.05116195841294	[]	[]	9	hSpCas9	negative selection	2604609
41117506	41117529	22	+	27260157	DLD1	viability	GGGCACTAGTGGACCAAATCAGG	EP300	ENSG00000100393	-0.354692527941855	[]	[]	-3	hSpCas9	negative selection	2604944
41093081	41093104	22	-	27260157	DLD1	viability	CTAACCTGTGCCATCGCTGGCGG	EP300	ENSG00000100393	-0.714353561008796	[]	[]	-5	hSpCas9	negative selection	2607228
41093069	41093092	22	-	27260157	DLD1	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.159114547598638	[]	[]	-1	hSpCas9	negative selection	2613221
41093084	41093107	22	-	27260157	DLD1	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-1.60326232066256	[]	[]	-8	hSpCas9	negative selection	2613993
41117222	41117245	22	-	27260157	DLD1	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	-0.304612682323662	[]	[]	-2	hSpCas9	negative selection	2615662
41093046	41093069	22	+	27260157	DLD1	viability	GCGGCCTAAACTCTCATCTCCGG	EP300	ENSG00000100393	-0.0857302751150836	[]	[]	0	hSpCas9	negative selection	2616337
41117333	41117356	22	+	27260157	DLD1	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-0.408880711399989	[]	[]	-3	hSpCas9	negative selection	2616835
41093055	41093078	22	+	27260157	DLD1	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	-0.0602184689183251	[]	[]	0	hSpCas9	negative selection	2616945
41117389	41117412	22	-	27260157	DLD1	viability	GGCTGGCCATGACTTGACCTGGG	EP300	ENSG00000100393	-0.872729098324394	[]	[]	-6	hSpCas9	negative selection	2619300
41093071	41093094	22	+	27260157	DLD1	viability	CTCTCGGCGTCCGCCAGCGATGG	EP300	ENSG00000100393	-0.724734702569823	[]	[]	-5	hSpCas9	negative selection	2619938
41093077	41093100	22	+	27260157	DLD1	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	0.449944715920743	[]	[]	7	hSpCas9	negative selection	2620180
41117406	41117429	22	-	27260157	DLD1	viability	ACTGCTCTGTTGGGCCTGGCTGG	EP300	ENSG00000100393	0.470316947623031	[]	[]	8	hSpCas9	negative selection	2622618
41093042	41093065	22	-	27260157	DLD1	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	0.0775041445249792	[]	[]	3	hSpCas9	negative selection	2624115
41117416	41117439	22	-	27260157	DLD1	viability	CTAATCCAGGACTGCTCTGTTGG	EP300	ENSG00000100393	0.372523144473956	[]	[]	4	hSpCas9	negative selection	2641167
41093032	41093055	22	-	27260157	DLD1	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	-1.2660255142957	[]	[]	-7	hSpCas9	negative selection	2647001
41093065	41093088	22	-	27260157	DLD1	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	-0.538442428479868	[]	[]	-4	hSpCas9	negative selection	2649406
41093007	41093030	22	+	27260157	HT1080	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	2.57147999419225	[]	[]	9	hSpCas9	negative selection	2653025
41117246	41117269	22	+	27260157	HT1080	viability	GAATTGGGACTAACCAATGGTGG	EP300	ENSG00000100393	1.45094412782528	[]	[]	9	hSpCas9	negative selection	2654645
41093050	41093073	22	-	27260157	HT1080	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	1.61532582152617	[]	[]	9	hSpCas9	negative selection	2680695
41093070	41093093	22	-	27260157	HT1080	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	2.79203219656392	[]	[]	9	hSpCas9	negative selection	2680739
41117506	41117529	22	+	27260157	HT1080	viability	GGGCACTAGTGGACCAAATCAGG	EP300	ENSG00000100393	0.776732782325193	[]	[]	6	hSpCas9	negative selection	2681074
41093081	41093104	22	-	27260157	HT1080	viability	CTAACCTGTGCCATCGCTGGCGG	EP300	ENSG00000100393	1.93795441740324	[]	[]	9	hSpCas9	negative selection	2683358
41093069	41093092	22	-	27260157	HT1080	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	2.51824114759809	[]	[]	9	hSpCas9	negative selection	2689351
41093084	41093107	22	-	27260157	HT1080	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	1.19099464491112	[]	[]	8	hSpCas9	negative selection	2690123
41117222	41117245	22	-	27260157	HT1080	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	1.5351542681035	[]	[]	9	hSpCas9	negative selection	2691792
41093046	41093069	22	+	27260157	HT1080	viability	GCGGCCTAAACTCTCATCTCCGG	EP300	ENSG00000100393	1.70002012529543	[]	[]	9	hSpCas9	negative selection	2692467
41117333	41117356	22	+	27260157	HT1080	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-0.0362308328814413	[]	[]	0	hSpCas9	negative selection	2692965
41093055	41093078	22	+	27260157	HT1080	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	2.15045191593331	[]	[]	9	hSpCas9	negative selection	2693075
41117389	41117412	22	-	27260157	HT1080	viability	GGCTGGCCATGACTTGACCTGGG	EP300	ENSG00000100393	1.80811651361862	[]	[]	9	hSpCas9	negative selection	2695430
41093071	41093094	22	+	27260157	HT1080	viability	CTCTCGGCGTCCGCCAGCGATGG	EP300	ENSG00000100393	1.90727503180406	[]	[]	9	hSpCas9	negative selection	2696068
41093077	41093100	22	+	27260157	HT1080	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	2.61092926784671	[]	[]	9	hSpCas9	negative selection	2696310
41117406	41117429	22	-	27260157	HT1080	viability	ACTGCTCTGTTGGGCCTGGCTGG	EP300	ENSG00000100393	1.20897491470443	[]	[]	8	hSpCas9	negative selection	2698748
41093042	41093065	22	-	27260157	HT1080	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	2.18790563465936	[]	[]	9	hSpCas9	negative selection	2700245
41117416	41117439	22	-	27260157	HT1080	viability	CTAATCCAGGACTGCTCTGTTGG	EP300	ENSG00000100393	1.44215664045645	[]	[]	9	hSpCas9	negative selection	2717297
41093032	41093055	22	-	27260157	HT1080	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	0.937020996936687	[]	[]	7	hSpCas9	negative selection	2723131
41093065	41093088	22	-	27260157	HT1080	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	1.86829438277638	[]	[]	9	hSpCas9	negative selection	2725536
41093007	41093030	22	+	27260157	MKN45	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	0.419851973166608	[]	[]	6	hSpCas9	negative selection	2729155
41117246	41117269	22	+	27260157	MKN45	viability	GAATTGGGACTAACCAATGGTGG	EP300	ENSG00000100393	-0.978938007634068	[]	[]	-7	hSpCas9	negative selection	2730775
41093050	41093073	22	-	27260157	MKN45	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	-0.722401232330989	[]	[]	-7	hSpCas9	negative selection	2756825
41093070	41093093	22	-	27260157	MKN45	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	0.563151965554271	[]	[]	7	hSpCas9	negative selection	2756869
41117506	41117529	22	+	27260157	MKN45	viability	GGGCACTAGTGGACCAAATCAGG	EP300	ENSG00000100393	-0.737551348885779	[]	[]	-7	hSpCas9	negative selection	2757204
41093081	41093104	22	-	27260157	MKN45	viability	CTAACCTGTGCCATCGCTGGCGG	EP300	ENSG00000100393	-0.424343891459997	[]	[]	-6	hSpCas9	negative selection	2759488
41093069	41093092	22	-	27260157	MKN45	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.360040797161266	[]	[]	6	hSpCas9	negative selection	2765481
41093084	41093107	22	-	27260157	MKN45	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-0.783563451765142	[]	[]	-7	hSpCas9	negative selection	2766253
41117222	41117245	22	-	27260157	MKN45	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	-0.85575229058364	[]	[]	-7	hSpCas9	negative selection	2767922
41093046	41093069	22	+	27260157	MKN45	viability	GCGGCCTAAACTCTCATCTCCGG	EP300	ENSG00000100393	-0.246392191994941	[]	[]	-1	hSpCas9	negative selection	2768597
41117333	41117356	22	+	27260157	MKN45	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-1.60799349287228	[]	[]	-9	hSpCas9	negative selection	2769095
41093055	41093078	22	+	27260157	MKN45	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	-0.49146527711253	[]	[]	-6	hSpCas9	negative selection	2769205
41117389	41117412	22	-	27260157	MKN45	viability	GGCTGGCCATGACTTGACCTGGG	EP300	ENSG00000100393	0.533786425161819	[]	[]	6	hSpCas9	negative selection	2771560
41093071	41093094	22	+	27260157	MKN45	viability	CTCTCGGCGTCCGCCAGCGATGG	EP300	ENSG00000100393	-0.839941128705592	[]	[]	-7	hSpCas9	negative selection	2772198
41093077	41093100	22	+	27260157	MKN45	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	0.129684623156532	[]	[]	4	hSpCas9	negative selection	2772440
41117406	41117429	22	-	27260157	MKN45	viability	ACTGCTCTGTTGGGCCTGGCTGG	EP300	ENSG00000100393	0.991585394701407	[]	[]	8	hSpCas9	negative selection	2774878
41093042	41093065	22	-	27260157	MKN45	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	-0.531491544784399	[]	[]	-6	hSpCas9	negative selection	2776375
41117416	41117439	22	-	27260157	MKN45	viability	CTAATCCAGGACTGCTCTGTTGG	EP300	ENSG00000100393	0.71808987175904	[]	[]	7	hSpCas9	negative selection	2793427
41093032	41093055	22	-	27260157	MKN45	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	-0.83882126786286	[]	[]	-7	hSpCas9	negative selection	2799261
41093065	41093088	22	-	27260157	MKN45	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	0.167502180802191	[]	[]	5	hSpCas9	negative selection	2801666
41093007	41093030	22	+	27260157	RKO	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	0.470675392534718	[]	[]	2	hSpCas9	negative selection	2805285
41117246	41117269	22	+	27260157	RKO	viability	GAATTGGGACTAACCAATGGTGG	EP300	ENSG00000100393	-0.131445008276926	[]	[]	0	hSpCas9	negative selection	2806905
41093050	41093073	22	-	27260157	RKO	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	-0.718049927695711	[]	[]	-7	hSpCas9	negative selection	2832955
41093070	41093093	22	-	27260157	RKO	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	1.19142244191219	[]	[]	9	hSpCas9	negative selection	2832999
41117506	41117529	22	+	27260157	RKO	viability	GGGCACTAGTGGACCAAATCAGG	EP300	ENSG00000100393	0.397494332869826	[]	[]	2	hSpCas9	negative selection	2833334
41093081	41093104	22	-	27260157	RKO	viability	CTAACCTGTGCCATCGCTGGCGG	EP300	ENSG00000100393	-0.0600536572400679	[]	[]	0	hSpCas9	negative selection	2835618
41093069	41093092	22	-	27260157	RKO	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.54774820194976	[]	[]	3	hSpCas9	negative selection	2841611
41093084	41093107	22	-	27260157	RKO	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-0.580766191686009	[]	[]	-7	hSpCas9	negative selection	2842383
41117222	41117245	22	-	27260157	RKO	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	-0.130624136306773	[]	[]	0	hSpCas9	negative selection	2844052
41093046	41093069	22	+	27260157	RKO	viability	GCGGCCTAAACTCTCATCTCCGG	EP300	ENSG00000100393	-0.629827900316509	[]	[]	-7	hSpCas9	negative selection	2844727
41117333	41117356	22	+	27260157	RKO	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-1.22043516271474	[]	[]	-8	hSpCas9	negative selection	2845225
41093055	41093078	22	+	27260157	RKO	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	0.378984171760081	[]	[]	2	hSpCas9	negative selection	2845335
41117389	41117412	22	-	27260157	RKO	viability	GGCTGGCCATGACTTGACCTGGG	EP300	ENSG00000100393	-0.0723334196018869	[]	[]	0	hSpCas9	negative selection	2847690
41093071	41093094	22	+	27260157	RKO	viability	CTCTCGGCGTCCGCCAGCGATGG	EP300	ENSG00000100393	-0.117536555762883	[]	[]	0	hSpCas9	negative selection	2848328
41093077	41093100	22	+	27260157	RKO	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	-0.45994142225115	[]	[]	-6	hSpCas9	negative selection	2848570
41117406	41117429	22	-	27260157	RKO	viability	ACTGCTCTGTTGGGCCTGGCTGG	EP300	ENSG00000100393	0.987121145200905	[]	[]	9	hSpCas9	negative selection	2851008
41093042	41093065	22	-	27260157	RKO	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	-0.409691135331419	[]	[]	-6	hSpCas9	negative selection	2852505
41117416	41117439	22	-	27260157	RKO	viability	CTAATCCAGGACTGCTCTGTTGG	EP300	ENSG00000100393	-0.167114200501646	[]	[]	-1	hSpCas9	negative selection	2869557
41093032	41093055	22	-	27260157	RKO	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	0.472452094106782	[]	[]	2	hSpCas9	negative selection	2875391
41093065	41093088	22	-	27260157	RKO	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	0.0482647435361687	[]	[]	0	hSpCas9	negative selection	2877796
41093007	41093030	22	+	27260157	SF268	viability	GGCCGAGAATGTGGTGGAACCGG	EP300	ENSG00000100393	1.31240956315077	[]	[]	9	hSpCas9	negative selection	2881415
41117246	41117269	22	+	27260157	SF268	viability	GAATTGGGACTAACCAATGGTGG	EP300	ENSG00000100393	-0.400739954461634	[]	[]	-3	hSpCas9	negative selection	2883035
41093050	41093073	22	-	27260157	SF268	viability	AGGGCCGGAGATGAGAGTTTAGG	EP300	ENSG00000100393	0.303770627875975	[]	[]	4	hSpCas9	negative selection	2909085
41093070	41093093	22	-	27260157	SF268	viability	CATCGCTGGCGGACGCCGAGAGG	EP300	ENSG00000100393	1.23725834357099	[]	[]	9	hSpCas9	negative selection	2909129
41117506	41117529	22	+	27260157	SF268	viability	GGGCACTAGTGGACCAAATCAGG	EP300	ENSG00000100393	0.542759171354446	[]	[]	8	hSpCas9	negative selection	2909464
41093081	41093104	22	-	27260157	SF268	viability	CTAACCTGTGCCATCGCTGGCGG	EP300	ENSG00000100393	0.247972488691852	[]	[]	3	hSpCas9	negative selection	2911748
41093069	41093092	22	-	27260157	SF268	viability	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.791175815937885	[]	[]	8	hSpCas9	negative selection	2917741
41093084	41093107	22	-	27260157	SF268	viability	AAACTAACCTGTGCCATCGCTGG	EP300	ENSG00000100393	-0.638709541186088	[]	[]	-5	hSpCas9	negative selection	2918513
41117222	41117245	22	-	27260157	SF268	viability	GTAGAGTTGATTAATTCATCTGG	EP300	ENSG00000100393	-0.889457757195828	[]	[]	-6	hSpCas9	negative selection	2920182
41093046	41093069	22	+	27260157	SF268	viability	GCGGCCTAAACTCTCATCTCCGG	EP300	ENSG00000100393	0.384524515068997	[]	[]	4	hSpCas9	negative selection	2920857
41117333	41117356	22	+	27260157	SF268	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-0.382307919928104	[]	[]	-3	hSpCas9	negative selection	2921355
41093055	41093078	22	+	27260157	SF268	viability	ACTCTCATCTCCGGCCCTCTCGG	EP300	ENSG00000100393	0.384114219026358	[]	[]	4	hSpCas9	negative selection	2921465
41117389	41117412	22	-	27260157	SF268	viability	GGCTGGCCATGACTTGACCTGGG	EP300	ENSG00000100393	0.131560381614777	[]	[]	0	hSpCas9	negative selection	2923820
41093071	41093094	22	+	27260157	SF268	viability	CTCTCGGCGTCCGCCAGCGATGG	EP300	ENSG00000100393	-0.301348087467489	[]	[]	-2	hSpCas9	negative selection	2924458
41093077	41093100	22	+	27260157	SF268	viability	GCGTCCGCCAGCGATGGCACAGG	EP300	ENSG00000100393	0.656793942518824	[]	[]	8	hSpCas9	negative selection	2924700
41117406	41117429	22	-	27260157	SF268	viability	ACTGCTCTGTTGGGCCTGGCTGG	EP300	ENSG00000100393	0.68109496132262	[]	[]	8	hSpCas9	negative selection	2927138
41093042	41093065	22	-	27260157	SF268	viability	AGATGAGAGTTTAGGCCGCTTGG	EP300	ENSG00000100393	0.515221668023861	[]	[]	8	hSpCas9	negative selection	2928635
41117416	41117439	22	-	27260157	SF268	viability	CTAATCCAGGACTGCTCTGTTGG	EP300	ENSG00000100393	0.785432790694999	[]	[]	8	hSpCas9	negative selection	2945687
41093032	41093055	22	-	27260157	SF268	viability	TTAGGCCGCTTGGCTGAAGGCGG	EP300	ENSG00000100393	0.308963315471837	[]	[]	4	hSpCas9	negative selection	2951521
41093065	41093088	22	-	27260157	SF268	viability	CTGGCGGACGCCGAGAGGGCCGG	EP300	ENSG00000100393	0.28982333548207	[]	[]	4	hSpCas9	negative selection	2953926
41149038	41149061	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	-0.17135981347980206	[3,4]	[2,3]	-2	hSpCas9	positive selection	2985981
41149875	41149898	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.2916040669080574	[3,4]	[3,1]	-4	hSpCas9	positive selection	2985982
41157178	41157201	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	-0.5882026804182832	[4,4]	[2,1]	-7	hSpCas9	positive selection	2985983
41127525	41127548	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	-0.5044713462977055	[3,3]	[1,1]	-6	hSpCas9	positive selection	2985984
41149038	41149061	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	0.4583743223275178	[3,3]	[3,4]	7	hSpCas9	positive selection	3053839
41149875	41149898	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.10438004064695705	[3,3]	[2,1]	-1	hSpCas9	positive selection	3053840
41157178	41157201	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	-0.8372212292965353	[4,4]	[3,0]	-9	hSpCas9	positive selection	3053841
41127525	41127548	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	0.14068258991261537	[3,3]	[2,2]	2	hSpCas9	positive selection	3053842
41125873	41125896		+	24336571	A375	resistance to PLX after 7 days	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.06805886137751405	[15,17]	[15,16]	-2	hSpCas9	positive selection	3112160
41126017	41126040		-	24336571	A375	resistance to PLX after 7 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.34820134083538234	[17,20]	[24,24]	8	hSpCas9	positive selection	3112161
41117654	41117677		-	24336571	A375	resistance to PLX after 7 days	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	0.28471153628748935	[20,18]	[26,20]	7	hSpCas9	positive selection	3112162
41117356	41117379		+	24336571	A375	resistance to PLX after 7 days	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.3249408539714199	[19,25]	[16,18]	-8	hSpCas9	positive selection	3112164
41125873	41125896		+	24336571	A375	resistance to PLX after 14 days	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.7072074973244747	[20,21]	[5,5]	-8	hSpCas9	positive selection	3169953
41126017	41126040		-	24336571	A375	resistance to PLX after 14 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	3.0581004809681063	[14,13]	[50,64]	9	hSpCas9	positive selection	3169954
41117654	41117677		-	24336571	A375	resistance to PLX after 14 days	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	2.2569053976618543	[27,21]	[45,66]	9	hSpCas9	positive selection	3169955
41117356	41117379		+	24336571	A375	resistance to PLX after 14 days	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.4158744291093516	[17,22]	[13,11]	4	hSpCas9	positive selection	3169957
41125873	41125896		+	24336571	A375	viability after 7 days	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.07590918663655305	[18]	[15,17]	-1	hSpCas9	negative selection	3227746
41126017	41126040		-	24336571	A375	viability after 7 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.5066052995793612	[13]	[17,20]	7	hSpCas9	negative selection	3227747
41117654	41117677		-	24336571	A375	viability after 7 days	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	0.1586150031857511	[18]	[20,18]	2	hSpCas9	negative selection	3227748
41117356	41117379		+	24336571	A375	viability after 7 days	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.2810810518248785	[19]	[19,25]	4	hSpCas9	negative selection	3227750
41125873	41125896		+	24336571	A375	viability after 14 days	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.2612028768806135	[18]	[20,21]	3	hSpCas9	negative selection	3285539
41126017	41126040		-	24336571	A375	viability after 14 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.1045822345351567	[13]	[14,13]	1	hSpCas9	negative selection	3285540
41117654	41117677		-	24336571	A375	viability after 14 days	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	0.4966349125469391	[18]	[27,21]	6	hSpCas9	negative selection	3285541
41117356	41117379		+	24336571	A375	viability after 14 days	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.1467438030027569	[19]	[17,22]	2	hSpCas9	negative selection	3285543
41117333	41117356	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	-1.0228683722334606	[291,329]	[0,0]	-7	hSpCas9	positive selection	3348078
41127726	41127749	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.31642249904627706	[101,143]	[0,0]	1	hSpCas9	positive selection	3348079
41117356	41117379	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.016612810143634606	[111,190]	[0,0]	0	hSpCas9	positive selection	3348080
41127620	41127643	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.06750165256581787	[145,145]	[0,0]	0	hSpCas9	positive selection	3367291
41126017	41126040	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3367292
41125873	41125896	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.7256673632484749	[252,252]	[0,0]	-5	hSpCas9	positive selection	3367293
41149038	41149061	22	-	26780180	HT29	viability (Avana library 4 designs)	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	1.27351930197995	[]	[]	5	hSpCas9	negative selection	3422804
41149875	41149898	22	-	26780180	HT29	viability (Avana library 4 designs)	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	1.1234796421156	[]	[]	4	hSpCas9	negative selection	3422805
41157177	41157200	22	+	26780180	HT29	viability (Avana library 4 designs)	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	1.21004310226606	[]	[]	5	hSpCas9	negative selection	3422806
41127524	41127547	22	+	26780180	HT29	viability (Avana library 4 designs)	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	0.70636462590851	[]	[]	2	hSpCas9	negative selection	3422807
41127524	41127547	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	3.87747268123219	[]	[]	6	hSpCas9	negative selection	3503643
41149875	41149898	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	7.11830639055963	[]	[]	9	hSpCas9	negative selection	3503644
41149038	41149061	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	4.70539703554676	[]	[]	7	hSpCas9	negative selection	3503645
41157177	41157200	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	2.21194801152375	[]	[]	3	hSpCas9	negative selection	3503646
41147884	41147907	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGAGGAGGGGTTTGCCGGGG	EP300	ENSG00000100393	4.34880402290323	[]	[]	7	hSpCas9	negative selection	3503647
41146750	41146773	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGACCCAAGTATGATCCGTGG	EP300	ENSG00000100393	8.25772125736201	[]	[]	9	hSpCas9	negative selection	3503648
41127524	41127547	22	+	26780180	A375	viability (Avana lentiGuide)	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	-2.01475764813282	[]	[]	-3	hSpCas9	negative selection	3612302
41149875	41149898	22	-	26780180	A375	viability (Avana lentiGuide)	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-5.08317368782109	[]	[]	-8	hSpCas9	negative selection	3612303
41149038	41149061	22	-	26780180	A375	viability (Avana lentiGuide)	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	-4.75734226177265	[]	[]	-7	hSpCas9	negative selection	3612304
41157177	41157200	22	+	26780180	A375	viability (Avana lentiGuide)	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	-7.93987778039041	[]	[]	-9	hSpCas9	negative selection	3612305
41147884	41147907	22	-	26780180	A375	viability (Avana lentiGuide)	TGAAGAGGAGGGGTTTGCCGGGG	EP300	ENSG00000100393	-4.8687225294691	[]	[]	-8	hSpCas9	negative selection	3612306
41146750	41146773	22	+	26780180	A375	viability (Avana lentiGuide)	CCTGACCCAAGTATGATCCGTGG	EP300	ENSG00000100393	-5.20378813884506	[]	[]	-8	hSpCas9	negative selection	3612307
41127524	41127547	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	0.12646371511829407	[5]	[5,5]	3	hSpCas9	positive selection	3720961
41149875	41149898	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.2533323355613196	[5]	[7,6]	7	hSpCas9	positive selection	3720962
41149038	41149061	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	0.17963102124396627	[5]	[6,6]	5	hSpCas9	positive selection	3720963
41157177	41157200	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	0.17778670883525127	[5]	[6,6]	5	hSpCas9	positive selection	3720964
41147884	41147907	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGAGGAGGGGTTTGCCGGGG	EP300	ENSG00000100393	0.41572203193875923	[4]	[5,6]	9	hSpCas9	positive selection	3720965
41146750	41146773	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGACCCAAGTATGATCCGTGG	EP300	ENSG00000100393	0.3970177488265531	[4]	[5,6]	9	hSpCas9	positive selection	3720966
41127524	41127547	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTGACTCCAGTTGCCCAAGGG	EP300	ENSG00000100393	0.3843378605573459	[5]	[6,6]	9	hSpCas9	positive selection	3829568
41149875	41149898	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.05110538456926214	[6]	[4,4]	0	hSpCas9	positive selection	3829569
41149038	41149061	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACGAGGCCCATAGCCCATAGG	EP300	ENSG00000100393	0.21526253501283968	[6]	[6,6]	5	hSpCas9	positive selection	3829570
41157177	41157200	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATATTGTGAAGAGCCCCATGG	EP300	ENSG00000100393	0.4534998535592372	[6]	[7,7]	9	hSpCas9	positive selection	3829571
41147884	41147907	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGAGGAGGGGTTTGCCGGGG	EP300	ENSG00000100393	0.46258039451783156	[5]	[6,7]	9	hSpCas9	positive selection	3829572
41146750	41146773	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGACCCAAGTATGATCCGTGG	EP300	ENSG00000100393	0.41182274909891103	[5]	[6,6]	9	hSpCas9	positive selection	3829573
41125873	41125896	22	+	26780180	A375	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.370238151652699	[]	[]	0	hSpCas9	negative selection	3936919
41127620	41127643	22	+	26780180	A375	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	1.71434999479711	[]	[]	9	hSpCas9	negative selection	3936920
41126017	41126040	22	-	26780180	A375	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.14756968803052	[]	[]	6	hSpCas9	negative selection	3936921
41117333	41117356	22	+	26780180	A375	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.305128026596747	[]	[]	0	hSpCas9	negative selection	3936922
41127726	41127749	22	-	26780180	A375	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.220457208064251	[]	[]	0	hSpCas9	negative selection	3936923
41117356	41117379	22	+	26780180	A375	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.27958205794539	[]	[]	-7	hSpCas9	negative selection	3936924
41125873	41125896	22	+	26780180	HT29	viability (GeCKOv2 library)	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.0466789794249475	[]	[]	0	hSpCas9	negative selection	4044885
41127620	41127643	22	+	26780180	HT29	viability (GeCKOv2 library)	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	1.44714089799316	[]	[]	7	hSpCas9	negative selection	4044886
41126017	41126040	22	-	26780180	HT29	viability (GeCKOv2 library)	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.29355757731442	[]	[]	6	hSpCas9	negative selection	4044887
41117333	41117356	22	+	26780180	HT29	viability (GeCKOv2 library)	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.21478829231499	[]	[]	0	hSpCas9	negative selection	4044888
41127726	41127749	22	-	26780180	HT29	viability (GeCKOv2 library)	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.748521611159091	[]	[]	3	hSpCas9	negative selection	4044889
41117356	41117379	22	+	26780180	HT29	viability (GeCKOv2 library)	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.310109834395684	[]	[]	0	hSpCas9	negative selection	4044890
41125873	41125896	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.07942224973240153	[3]	[2,2]	2	hSpCas9	positive selection	4134861
41126017	41126040	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.5970194477866976	[3]	[2,5]	9	hSpCas9	positive selection	4134862
41117654	41117677	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	0.49657501259699055	[4]	[2,5]	9	hSpCas9	positive selection	4134863
41117356	41117379	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.38261379292347913	[3]	[3,3]	8	hSpCas9	positive selection	4134865
41125873	41125896	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.45167633881993274	[3]	[0,1,1,0]	-6	hSpCas9	positive selection	4198883
41126017	41126040	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.3312356480264227	[3]	[3,4,1,0]	2	hSpCas9	positive selection	4198884
41117654	41117677	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACCGTTCATGACTTGATTAGG	EP300	ENSG00000100393	1.0028188454536744	[3]	[1,2,2,3]	7	hSpCas9	positive selection	4198885
41117356	41117379	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.1814679345977872	[4]	[3,5,4,4]	8	hSpCas9	positive selection	4198887
41117333	41117356	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.33168322353259927	[3]	[4,3]	6	hSpCas9	positive selection	4268919
41127726	41127749	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.049515951230383826	[2]	[2,1]	1	hSpCas9	positive selection	4268920
41117356	41117379	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.11792165786247558	[2]	[3,0]	2	hSpCas9	positive selection	4268921
41127620	41127643	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.17805748712317648	[2]	[1,1]	-4	hSpCas9	positive selection	4333184
41126017	41126040	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.04271232011721676	[2]	[1,1]	-1	hSpCas9	positive selection	4333185
41125873	41125896	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.6812740167688555	[2]	[3,4]	9	hSpCas9	positive selection	4333186
41146750	41146772	22	-	27760321	OCIAML3	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	-0.24909095255308783	[646,490]	[357,388]	-3	hSpCas9	negative selection	4397894
41147868	41147890	22	-	27760321	OCIAML3	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	-0.17196652706638565	[571,435]	[278,435]	-2	hSpCas9	negative selection	4397895
41149875	41149897	22	-	27760321	OCIAML3	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.23086624542419726	[398,299]	[187,286]	-2	hSpCas9	negative selection	4397896
41127633	41127655	22	-	27760321	OCIAML3	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.9464146756318753	[1265,1121]	[445,532]	-7	hSpCas9	negative selection	4397897
41140148	41140170	22	-	27760321	OCIAML3	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-2.258581714989189	[184,163]	[24,32]	-9	hSpCas9	negative selection	4397898
41146750	41146772	22	-	27760321	OCIAML2	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	-0.7042584959630016	[646,490]	[262,302]	-6	hSpCas9	negative selection	4481357
41147868	41147890	22	-	27760321	OCIAML2	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.2458639047588153	[571,435]	[480,477]	3	hSpCas9	negative selection	4481358
41149875	41149897	22	-	27760321	OCIAML2	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.8827691270385609	[398,299]	[164,134]	-7	hSpCas9	negative selection	4481359
41127633	41127655	22	-	27760321	OCIAML2	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.7853273560181292	[1265,1121]	[527,600]	-7	hSpCas9	negative selection	4481360
41140148	41140170	22	-	27760321	OCIAML2	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-3.386836170678987	[184,163]	[6,21]	-9	hSpCas9	negative selection	4481361
41146750	41146772	22	-	27760321	MV411	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	-0.016923396819455094	[646,490]	[304,462]	0	hSpCas9	negative selection	4564820
41147868	41147890	22	-	27760321	MV411	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.6984056460407477	[571,435]	[646,367]	5	hSpCas9	negative selection	4564821
41149875	41149897	22	-	27760321	MV411	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-2.301393577343677	[398,299]	[43,49]	-8	hSpCas9	negative selection	4564822
41127633	41127655	22	-	27760321	MV411	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.639676235701433	[1265,1121]	[131,1064]	-4	hSpCas9	negative selection	4564823
41140148	41140170	22	-	27760321	MV411	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-1.575651371262467	[184,163]	[0,94]	-7	hSpCas9	negative selection	4564824
41146750	41146772	22	-	27760321	HL60	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.04936693338399051	[646,490]	[448,506]	0	hSpCas9	negative selection	4648283
41147868	41147890	22	-	27760321	HL60	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.15117748324369895	[571,435]	[374,536]	1	hSpCas9	negative selection	4648284
41149875	41149897	22	-	27760321	HL60	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.6569608102401703	[398,299]	[197,159]	-6	hSpCas9	negative selection	4648285
41127633	41127655	22	-	27760321	HL60	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-1.2757360628754728	[1265,1121]	[390,413]	-8	hSpCas9	negative selection	4648286
41140148	41140170	22	-	27760321	HL60	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-1.0539276603145422	[184,163]	[69,66]	-8	hSpCas9	negative selection	4648287
41146750	41146772	22	-	27760321	HT1080	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	5.777050273820778	[490,382]	[8838,10319]	9	hSpCas9	negative selection	4731746
41147868	41147890	22	-	27760321	HT1080	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	6.460201843066074	[435,339]	[16032,10953]	9	hSpCas9	negative selection	4731747
41149875	41149897	22	-	27760321	HT1080	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	5.703049483845176	[299,233]	[5725,5337]	9	hSpCas9	negative selection	4731748
41127633	41127655	22	-	27760321	HT1080	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	4.792680341059867	[1121,875]	[10370,11752]	9	hSpCas9	negative selection	4731749
41140148	41140170	22	-	27760321	HT1080	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	6.318186955180346	[163,127]	[3848,5507]	9	hSpCas9	negative selection	4731750
41146750	41146772	22	-	27760321	HT29	viability after 7 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.3725665377156184	[490,382]	[835,550,806]	5	hSpCas9	negative selection	4815209
41147868	41147890	22	-	27760321	HT29	viability after 7 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.6029662573087422	[435,339]	[714,673,872]	8	hSpCas9	negative selection	4815210
41149875	41149897	22	-	27760321	HT29	viability after 7 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.32324611302642975	[299,233]	[397,220,222]	-4	hSpCas9	negative selection	4815211
41127633	41127655	22	-	27760321	HT29	viability after 7 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.38163452458283875	[1121,875]	[1233,1004,759]	-5	hSpCas9	negative selection	4815212
41140148	41140170	22	-	27760321	HT29	viability after 7 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-0.00873479081621098	[163,127]	[255,114,197]	0	hSpCas9	negative selection	4815213
41146750	41146772	22	-	27760321	HT29	viability after 25 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	1.5482103621692387	[490,382]	[1655,1508,1171]	9	hSpCas9	negative selection	4898672
41147868	41147890	22	-	27760321	HT29	viability after 25 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	1.55001493626887	[435,339]	[971,1415,1551]	9	hSpCas9	negative selection	4898673
41149875	41149897	22	-	27760321	HT29	viability after 25 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.6990639827690744	[299,233]	[462,350,693]	7	hSpCas9	negative selection	4898674
41127633	41127655	22	-	27760321	HT29	viability after 25 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.5287031677602521	[1121,875]	[710,772,905]	-5	hSpCas9	negative selection	4898675
41140148	41140170	22	-	27760321	HT29	viability after 25 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	0.37330300823210205	[163,127]	[210,77,375]	4	hSpCas9	negative selection	4898676
41146750	41146772	22	-	27760321	HT29	viability after 22 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	1.0744491985695108	[490,382]	[1244,944,995]	9	hSpCas9	negative selection	4982135
41147868	41147890	22	-	27760321	HT29	viability after 22 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	1.1186929616557286	[435,339]	[932,1222,764]	9	hSpCas9	negative selection	4982136
41149875	41149897	22	-	27760321	HT29	viability after 22 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.7747419422556843	[299,233]	[518,373,692]	8	hSpCas9	negative selection	4982137
41127633	41127655	22	-	27760321	HT29	viability after 22 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.39215015310609	[1121,875]	[595,937,1115]	-4	hSpCas9	negative selection	4982138
41140148	41140170	22	-	27760321	HT29	viability after 22 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-0.024444774855824747	[163,127]	[258,103,131]	0	hSpCas9	negative selection	4982139
41146750	41146772	22	-	27760321	HT29	viability after 19 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	1.0960487476225058	[490,382]	[1342,1194,708]	9	hSpCas9	negative selection	5065598
41147868	41147890	22	-	27760321	HT29	viability after 19 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	1.100332384012381	[435,339]	[874,1167,807]	9	hSpCas9	negative selection	5065599
41149875	41149897	22	-	27760321	HT29	viability after 19 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.08371892575209533	[299,233]	[516,208,266]	0	hSpCas9	negative selection	5065600
41127633	41127655	22	-	27760321	HT29	viability after 19 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.20845939998704677	[1121,875]	[858,1177,917]	-2	hSpCas9	negative selection	5065601
41140148	41140170	22	-	27760321	HT29	viability after 19 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-0.5896614392950146	[163,127]	[224,15,103]	-5	hSpCas9	negative selection	5065602
41146750	41146772	22	-	27760321	HT29	viability after 16 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.7932491969983775	[490,382]	[1364,522,710]	8	hSpCas9	negative selection	5149061
41147868	41147890	22	-	27760321	HT29	viability after 16 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.5079635642513589	[435,339]	[525,773,538]	6	hSpCas9	negative selection	5149062
41149875	41149897	22	-	27760321	HT29	viability after 16 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.27676508316888576	[299,233]	[264,339,471]	3	hSpCas9	negative selection	5149063
41127633	41127655	22	-	27760321	HT29	viability after 16 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.5712778250981059	[1121,875]	[619,1062,552]	-5	hSpCas9	negative selection	5149064
41140148	41140170	22	-	27760321	HT29	viability after 16 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-0.22245182396322472	[163,127]	[35,222,148]	-3	hSpCas9	negative selection	5149065
41146750	41146772	22	-	27760321	HT29	viability after 13 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.3875676891607645	[490,382]	[886,678,436]	5	hSpCas9	negative selection	5232524
41147868	41147890	22	-	27760321	HT29	viability after 13 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.7763353102791235	[435,339]	[800,918,602]	8	hSpCas9	negative selection	5232525
41149875	41149897	22	-	27760321	HT29	viability after 13 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.12679009555707121	[299,233]	[347,285,377]	1	hSpCas9	negative selection	5232526
41127633	41127655	22	-	27760321	HT29	viability after 13 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.8639946040791636	[1121,875]	[612,587,704]	-7	hSpCas9	negative selection	5232527
41140148	41140170	22	-	27760321	HT29	viability after 13 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	0.15085620874634476	[163,127]	[207,132,220]	1	hSpCas9	negative selection	5232528
41146750	41146772	22	-	27760321	HT29	viability after 10 days	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.3207061801582333	[490,382]	[818,736,493]	4	hSpCas9	negative selection	5315987
41147868	41147890	22	-	27760321	HT29	viability after 10 days	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	0.6840258329573807	[435,339]	[987,730,617]	8	hSpCas9	negative selection	5315988
41149875	41149897	22	-	27760321	HT29	viability after 10 days	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	0.2010605357208618	[299,233]	[344,208,585]	2	hSpCas9	negative selection	5315989
41127633	41127655	22	-	27760321	HT29	viability after 10 days	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-0.6177774300020482	[1121,875]	[697,1055,693]	-6	hSpCas9	negative selection	5315990
41140148	41140170	22	-	27760321	HT29	viability after 10 days	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	-0.2632431684737697	[163,127]	[167,131,154]	-3	hSpCas9	negative selection	5315991
41146750	41146772	22	-	27760321	MOLM13	viability	CACGGATCATACTTGGGTCAGG	EP300	ENSG00000100393	0.5090890447212553	[646,490]	[86,764]	3	hSpCas9	negative selection	5399450
41147868	41147890	22	-	27760321	MOLM13	viability	CCGGGGTACAATAGGGGGCTGG	EP300	ENSG00000100393	-0.5293391349894545	[571,435]	[309,97]	-3	hSpCas9	negative selection	5399451
41149875	41149897	22	-	27760321	MOLM13	viability	TACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.6598909162334068	[398,299]	[123,8]	-7	hSpCas9	negative selection	5399452
41127633	41127655	22	-	27760321	MOLM13	viability	ATTGGCCTGTTCCCGGCGCTGG	EP300	ENSG00000100393	-1.8170643836520848	[1265,1121]	[185,194]	-7	hSpCas9	negative selection	5399453
41140148	41140170	22	-	27760321	MOLM13	viability	GGATCCGGCGTAGGAAATATGG	EP300	ENSG00000100393	0.23852367295246868	[184,163]	[250,0]	1	hSpCas9	negative selection	5399454
41091821	41091844	22	+	27661255	K562	viability	GAGAGAGAGCGGGCGAGAGTGGG	EP300	ENSG00000100393	0.21240075195029418	[954,1244]	[1050,980]	7	dCas9-KRAB	negative selection	5477467
41091896	41091919	22	+	27661255	K562	viability	GGAGTCGGGTCGGAGAGAGGCGG	EP300	ENSG00000100393	-0.18768005785329767	[1247,1226]	[939,806]	-5	dCas9-KRAB	negative selection	5477468
41092882	41092905	22	-	27661255	K562	viability	GGCTCCGACGGCACCCGAGGGGG	EP300	ENSG00000100393	0.018668672017385257	[664,619]	[539,503]	0	dCas9-KRAB	negative selection	5477469
41092915	41092938	22	-	27661255	K562	viability	GGTCCCCGCGCCGCACCCAGGGG	EP300	ENSG00000100393	-0.22532501520623138	[1337,1484]	[1088,854]	-6	dCas9-KRAB	negative selection	5477470
41117333	41117356	22	+	27260156	BXPC3	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.7485253701292274	[724]	[1108,1131,1599,1276]	9	hSpCas9	negative selection	5541379
41127726	41127749	22	-	27260156	BXPC3	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.47451789590620946	[456]	[569,639,633,839]	8	hSpCas9	negative selection	5541380
41117356	41117379	22	+	27260156	BXPC3	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.9312653490756443	[330]	[542,549,633,964]	9	hSpCas9	negative selection	5541381
41127620	41127643	22	+	27260156	BXPC3	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.23672351305403352	[422]	[392,539,558,613]	5	hSpCas9	negative selection	5605644
41126017	41126040	22	-	27260156	BXPC3	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.42783483330917743	[326]	[365,351,523,633]	8	hSpCas9	negative selection	5605645
41125873	41125896	22	+	27260156	BXPC3	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.5714267438516307	[431]	[622,688,641,737]	9	hSpCas9	negative selection	5605646
41117333	41117356	22	+	27260156	A673	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.2648751969232658	[724]	[1244,1021,1006,924]	6	hSpCas9	negative selection	5662630
41127726	41127749	22	-	27260156	A673	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.26871052444043364	[456]	[745,580,634,694]	6	hSpCas9	negative selection	5662631
41117356	41117379	22	+	27260156	A673	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.2976532681826142	[330]	[612,392,417,549]	7	hSpCas9	negative selection	5662632
41127620	41127643	22	+	27260156	A673	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.6389059752172873	[422]	[344,327,326,304]	-9	hSpCas9	negative selection	5726895
41126017	41126040	22	-	27260156	A673	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.2678095310901294	[326]	[402,296,240,375]	-6	hSpCas9	negative selection	5726896
41125873	41125896	22	+	27260156	A673	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.16297649882025855	[431]	[479,570,554,711]	4	hSpCas9	negative selection	5726897
41117333	41117356	22	+	27260156	A375	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.6730522005661628	[724]	[1343,1406,1299,1351]	8	hSpCas9	negative selection	5783881
41127726	41127749	22	-	27260156	A375	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.8556937533894516	[456]	[889,1176,1116,732]	9	hSpCas9	negative selection	5783882
41117356	41117379	22	+	27260156	A375	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.0503574322304317	[330]	[874,695,623,969]	9	hSpCas9	negative selection	5783883
41127620	41127643	22	+	27260156	A375	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.11265795485531385	[422]	[349,723,387,679]	1	hSpCas9	negative selection	5848146
41126017	41126040	22	-	27260156	A375	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.7174738280574002	[326]	[706,826,478,535]	9	hSpCas9	negative selection	5848147
41125873	41125896	22	+	27260156	A375	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.7386705971277356	[431]	[690,784,1300,606]	9	hSpCas9	negative selection	5848148
41117333	41117356	22	+	27260156	COLO741	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.32662608131973236	[724]	[1284,1133,1079]	6	hSpCas9	negative selection	5905132
41127726	41127749	22	-	27260156	COLO741	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.17025310988491496	[456]	[749,620,609]	3	hSpCas9	negative selection	5905133
41117356	41117379	22	+	27260156	COLO741	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.32508353560593495	[330]	[740,352,512]	6	hSpCas9	negative selection	5905134
41127620	41127643	22	+	27260156	COLO741	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.44163560130726764	[422]	[477,454,275]	-7	hSpCas9	negative selection	5969397
41126017	41126040	22	-	27260156	COLO741	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.13863933498321712	[326]	[411,356,371]	-3	hSpCas9	negative selection	5969398
41125873	41125896	22	+	27260156	COLO741	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.16268339467814258	[431]	[518,720,604]	3	hSpCas9	negative selection	5969399
41117333	41117356	22	+	27260156	CAL120	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.5964879596781112	[724]	[1836,1131,1196]	8	hSpCas9	negative selection	6026383
41127726	41127749	22	-	27260156	CAL120	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.8149973757360786	[456]	[1413,969,684]	9	hSpCas9	negative selection	6026384
41117356	41117379	22	+	27260156	CAL120	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.5617136943696324	[330]	[1537,1124,1035]	9	hSpCas9	negative selection	6026385
41127620	41127643	22	+	27260156	CAL120	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.09063094399162192	[422]	[687,537,475]	1	hSpCas9	negative selection	6090648
41126017	41126040	22	-	27260156	CAL120	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.9044250925276446	[326]	[824,919,552]	9	hSpCas9	negative selection	6090649
41125873	41125896	22	+	27260156	CAL120	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.7660566018832832	[431]	[1305,681,814]	9	hSpCas9	negative selection	6090650
41117333	41117356	22	+	27260156	CADOES1	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.1641366168815701	[724]	[741,719,781,778]	3	hSpCas9	negative selection	6147634
41127726	41127749	22	-	27260156	CADOES1	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.02174015685691251	[456]	[407,416,468,431]	0	hSpCas9	negative selection	6147635
41117356	41117379	22	+	27260156	CADOES1	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.16512834671872134	[330]	[281,345,327,427]	3	hSpCas9	negative selection	6147636
41127620	41127643	22	+	27260156	CADOES1	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.7234871302170903	[422]	[240,204,318,185]	-8	hSpCas9	negative selection	6211899
41126017	41126040	22	-	27260156	CADOES1	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.11775190513641476	[326]	[152,301,220,451]	-2	hSpCas9	negative selection	6211900
41125873	41125896	22	+	27260156	CADOES1	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.0412585051665129	[431]	[424,567,300,357]	0	hSpCas9	negative selection	6211901
41117333	41117356	22	+	27260156	EWS502	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.14141314345200018	[724]	[837,849,989,698]	2	hSpCas9	negative selection	6268885
41127726	41127749	22	-	27260156	EWS502	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.2080288455967589	[456]	[476,667,607,481]	3	hSpCas9	negative selection	6268886
41117356	41117379	22	+	27260156	EWS502	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.1388412086338513	[330]	[195,530,238,310]	-2	hSpCas9	negative selection	6268887
41127620	41127643	22	+	27260156	EWS502	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.8132191889380254	[422]	[209,232,284,300]	-8	hSpCas9	negative selection	6333150
41126017	41126040	22	-	27260156	EWS502	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.3777783033765244	[326]	[185,149,394,356]	-6	hSpCas9	negative selection	6333151
41125873	41125896	22	+	27260156	EWS502	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.09474172713137084	[431]	[384,553,427,338]	-2	hSpCas9	negative selection	6333152
41117333	41117356	22	+	27260156	EW8	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.23938602537026654	[724]	[786,562,662,773]	4	hSpCas9	negative selection	6390136
41127726	41127749	22	-	27260156	EW8	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.10073981372187257	[456]	[456,564,297,291]	1	hSpCas9	negative selection	6390137
41117356	41117379	22	+	27260156	EW8	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.06445927203485746	[330]	[288,220,254,263]	-1	hSpCas9	negative selection	6390138
41127620	41127643	22	+	27260156	EW8	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.7889268192058277	[422]	[156,205,170,258]	-8	hSpCas9	negative selection	6454401
41126017	41126040	22	-	27260156	EW8	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.18934716674139795	[326]	[371,129,213,230]	-4	hSpCas9	negative selection	6454402
41125873	41125896	22	+	27260156	EW8	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.09835606583256205	[431]	[241,362,337,352]	-2	hSpCas9	negative selection	6454403
41117333	41117356	22	+	27260156	CORL105	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.3455655679746583	[724]	[1103,1061,1042,1099]	6	hSpCas9	negative selection	6511387
41127726	41127749	22	-	27260156	CORL105	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.4802385950754987	[456]	[707,452,945,912]	8	hSpCas9	negative selection	6511388
41117356	41117379	22	+	27260156	CORL105	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.49601269081610283	[330]	[621,436,562,570]	8	hSpCas9	negative selection	6511389
41127620	41127643	22	+	27260156	CORL105	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.6177786697082019	[422]	[283,360,374,276]	-8	hSpCas9	negative selection	6575652
41126017	41126040	22	-	27260156	CORL105	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.028912283101700964	[326]	[486,253,465,372]	0	hSpCas9	negative selection	6575653
41125873	41125896	22	+	27260156	CORL105	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.38333562961543904	[431]	[595,493,968,628]	7	hSpCas9	negative selection	6575654
41117333	41117356	22	+	27260156	HS294T	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.9252759976208993	[724]	[616,544,348,622]	9	hSpCas9	negative selection	6632638
41127726	41127749	22	-	27260156	HS294T	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	1.2468957573808497	[456]	[600,474,242,320]	9	hSpCas9	negative selection	6632639
41117356	41117379	22	+	27260156	HS294T	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.9208390217509175	[330]	[214,352,202,186]	9	hSpCas9	negative selection	6632640
41127620	41127643	22	+	27260156	HS294T	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.06645924330507139	[422]	[172,186,102,158]	-1	hSpCas9	negative selection	6696903
41126017	41126040	22	-	27260156	HS294T	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.37004382446861084	[326]	[260,123,120,133]	5	hSpCas9	negative selection	6696904
41125873	41125896	22	+	27260156	HS294T	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	1.00799857629786	[431]	[313,259,428,345]	9	hSpCas9	negative selection	6696905
41117333	41117356	22	+	27260156	HCC44	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.4415230606895155	[724]	[1564,888,1210,877]	7	hSpCas9	negative selection	6753889
41127726	41127749	22	-	27260156	HCC44	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.6586244245107163	[456]	[1164,611,911,650]	9	hSpCas9	negative selection	6753890
41117356	41117379	22	+	27260156	HCC44	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.27005528630575	[330]	[892,983,1221,558]	9	hSpCas9	negative selection	6753891
41127620	41127643	22	+	27260156	HCC44	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.1032193017596886	[422]	[447,541,420,610]	1	hSpCas9	negative selection	6818154
41126017	41126040	22	-	27260156	HCC44	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.24834512669721837	[326]	[297,287,696,520]	4	hSpCas9	negative selection	6818155
41125873	41125896	22	+	27260156	HCC44	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.576223085670458	[431]	[607,645,827,839]	8	hSpCas9	negative selection	6818156
41117333	41117356	22	+	27260156	G402	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.21627104714285794	[724]	[1041,1221,632,1213]	2	hSpCas9	negative selection	6875140
41127726	41127749	22	-	27260156	G402	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.354732451360424	[456]	[729,998,265,865]	4	hSpCas9	negative selection	6875141
41117356	41117379	22	+	27260156	G402	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.181219287331235	[330]	[449,702,420,277]	2	hSpCas9	negative selection	6875142
41127620	41127643	22	+	27260156	G402	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.5385212079867675	[422]	[212,200,228,728]	-6	hSpCas9	negative selection	6939405
41126017	41126040	22	-	27260156	G402	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.4841701934499587	[326]	[259,465,182,239]	-6	hSpCas9	negative selection	6939406
41125873	41125896	22	+	27260156	G402	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.032823447343752726	[431]	[565,601,572,426]	0	hSpCas9	negative selection	6939407
41117333	41117356	22	+	27260156	L33	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.32062108012805113	[724]	[1020,368,531,850]	6	hSpCas9	negative selection	6996391
41127726	41127749	22	-	27260156	L33	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.07220461632145159	[456]	[482,159,336,511]	1	hSpCas9	negative selection	6996392
41117356	41117379	22	+	27260156	L33	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.4748027108536975	[330]	[324,211,322,486]	8	hSpCas9	negative selection	6996393
41127620	41127643	22	+	27260156	L33	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.5763789075887592	[422]	[261,119,163,318]	-8	hSpCas9	negative selection	7060656
41126017	41126040	22	-	27260156	L33	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.05303062714032669	[326]	[338,103,255,260]	-1	hSpCas9	negative selection	7060657
41125873	41125896	22	+	27260156	L33	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.47850305571999	[431]	[659,243,431,464]	8	hSpCas9	negative selection	7060658
41117333	41117356	22	+	27260156	K562	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.2596821760115511	[724]	[770,723,909,680]	3	hSpCas9	negative selection	7117642
41127726	41127749	22	-	27260156	K562	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.334311058000124	[456]	[306,703,556,472]	4	hSpCas9	negative selection	7117643
41117356	41117379	22	+	27260156	K562	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.15514631463522133	[330]	[470,202,459,193]	2	hSpCas9	negative selection	7117644
41127620	41127643	22	+	27260156	K562	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.47836386700468736	[422]	[253,182,299,326]	-5	hSpCas9	negative selection	7181907
41126017	41126040	22	-	27260156	K562	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.1683823707779828	[326]	[487,444,227,178]	2	hSpCas9	negative selection	7181908
41125873	41125896	22	+	27260156	K562	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.49425842343104626	[431]	[608,470,475,596]	6	hSpCas9	negative selection	7181909
41117333	41117356	22	+	27260156	HT29	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.24089059985227934	[724]	[1305,1147,882,871]	5	hSpCas9	negative selection	7238893
41127726	41127749	22	-	27260156	HT29	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.002178236883096603	[456]	[560,553,544,560]	0	hSpCas9	negative selection	7238894
41117356	41117379	22	+	27260156	HT29	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.5399665008207155	[330]	[331,281,248,249]	-7	hSpCas9	negative selection	7238895
41127620	41127643	22	+	27260156	HT29	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.688899604158077	[422]	[334,349,376,226]	-8	hSpCas9	negative selection	7303158
41126017	41126040	22	-	27260156	HT29	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.7804570539935083	[326]	[359,145,264,163]	-8	hSpCas9	negative selection	7303159
41125873	41125896	22	+	27260156	HT29	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.09656168267021095	[431]	[625,540,488,585]	1	hSpCas9	negative selection	7303160
41117333	41117356	22	+	27260156	MHHES1	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.11829772788136794	[724]	[1008,1083,818,692]	2	hSpCas9	negative selection	7360144
41127726	41127749	22	-	27260156	MHHES1	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.20259977150579098	[456]	[816,533,560,488]	4	hSpCas9	negative selection	7360145
41117356	41117379	22	+	27260156	MHHES1	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.4851515075379954	[330]	[612,443,574,460]	8	hSpCas9	negative selection	7360146
41127620	41127643	22	+	27260156	MHHES1	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.7332041101306387	[422]	[361,213,458,141]	-8	hSpCas9	negative selection	7424409
41126017	41126040	22	-	27260156	MHHES1	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.24764477935102247	[326]	[458,441,217,176]	-5	hSpCas9	negative selection	7424410
41125873	41125896	22	+	27260156	MHHES1	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.24662210383829242	[431]	[446,479,356,367]	-5	hSpCas9	negative selection	7424411
41117333	41117356	22	+	27260156	MEWO	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.28301228268988243	[724]	[875,928,679]	6	hSpCas9	negative selection	7481395
41127726	41127749	22	-	27260156	MEWO	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.28818954527332385	[456]	[683,421,491]	6	hSpCas9	negative selection	7481396
41117356	41117379	22	+	27260156	MEWO	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.29770659384077525	[330]	[403,456,284]	6	hSpCas9	negative selection	7481397
41127620	41127643	22	+	27260156	MEWO	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.14362837816969057	[422]	[396,389,294]	-3	hSpCas9	negative selection	7545660
41126017	41126040	22	-	27260156	MEWO	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.0034008720717580987	[326]	[372,252,306]	0	hSpCas9	negative selection	7545661
41125873	41125896	22	+	27260156	MEWO	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.011210672664497823	[431]	[495,414,327]	0	hSpCas9	negative selection	7545662
41117333	41117356	22	+	27260156	LNCAPCLONEFGC	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.30564512352059925	[724]	[921,791,821,710]	5	hSpCas9	negative selection	7602646
41127726	41127749	22	-	27260156	LNCAPCLONEFGC	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.1961323952834141	[456]	[392,528,435,530]	3	hSpCas9	negative selection	7602647
41117356	41117379	22	+	27260156	LNCAPCLONEFGC	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.5848022243742759	[330]	[183,186,228,204]	-7	hSpCas9	negative selection	7602648
41127620	41127643	22	+	27260156	LNCAPCLONEFGC	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.48750194400650526	[422]	[280,259,220,323]	-6	hSpCas9	negative selection	7666911
41126017	41126040	22	-	27260156	LNCAPCLONEFGC	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.8107443584923812	[326]	[187,110,250,140]	-8	hSpCas9	negative selection	7666912
41125873	41125896	22	+	27260156	LNCAPCLONEFGC	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.08211018970077175	[431]	[366,476,437,374]	1	hSpCas9	negative selection	7666913
41117333	41117356	22	+	27260156	PANC0327	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.6704922785972127	[724]	[846,1051,1162,1019]	8	hSpCas9	negative selection	7723897
41127726	41127749	22	-	27260156	PANC0327	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.6406032391478078	[456]	[538,297,1246,483]	8	hSpCas9	negative selection	7723898
41117356	41117379	22	+	27260156	PANC0327	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.0970746510452072	[330]	[656,564,502,800]	9	hSpCas9	negative selection	7723899
41127620	41127643	22	+	27260156	PANC0327	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.00036987145748867967	[422]	[365,152,672,338]	0	hSpCas9	negative selection	7788162
41126017	41126040	22	-	27260156	PANC0327	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.31357374575425034	[326]	[394,512,280,237]	4	hSpCas9	negative selection	7788163
41125873	41125896	22	+	27260156	PANC0327	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.541794507617965	[431]	[814,531,537,373]	7	hSpCas9	negative selection	7788164
41117333	41117356	22	+	27260156	NCIH2009	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.7349126857033728	[724]	[2466,1246,1502]	8	hSpCas9	negative selection	7845148
41127726	41127749	22	-	27260156	NCIH2009	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.44086428496704505	[456]	[1093,788,761]	6	hSpCas9	negative selection	7845149
41117356	41117379	22	+	27260156	NCIH2009	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.369023309338234	[330]	[1484,1024,1131]	9	hSpCas9	negative selection	7845150
41127620	41127643	22	+	27260156	NCIH2009	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.09725438179346277	[422]	[700,432,553]	-1	hSpCas9	negative selection	7909413
41126017	41126040	22	-	27260156	NCIH2009	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.3390370252071233	[326]	[566,553,609]	4	hSpCas9	negative selection	7909414
41125873	41125896	22	+	27260156	NCIH2009	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.875039840198138	[431]	[1225,1029,1087]	9	hSpCas9	negative selection	7909415
41117333	41117356	22	+	27260156	NCIH1373	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.7003170237249949	[724]	[1098,822,1605,469]	7	hSpCas9	negative selection	7966399
41127726	41127749	22	-	27260156	NCIH1373	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.864367980425999	[456]	[617,638,767,455]	8	hSpCas9	negative selection	7966400
41117356	41117379	22	+	27260156	NCIH1373	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.621491698757559	[330]	[822,391,437,182]	6	hSpCas9	negative selection	7966401
41127620	41127643	22	+	27260156	NCIH1373	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.26649376497044586	[422]	[800,255,396,48]	-3	hSpCas9	negative selection	8030664
41126017	41126040	22	-	27260156	NCIH1373	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.07773440143506594	[326]	[664,180,197,109]	0	hSpCas9	negative selection	8030665
41125873	41125896	22	+	27260156	NCIH1373	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.45890077710387495	[431]	[1070,423,357,240]	4	hSpCas9	negative selection	8030666
41117333	41117356	22	+	27260156	PATU8902	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.6126991060197418	[724]	[1683,1400,1231,1976]	6	hSpCas9	negative selection	8087650
41127726	41127749	22	-	27260156	PATU8902	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	1.068229274705629	[456]	[1475,1115,1131,1696]	9	hSpCas9	negative selection	8087651
41117356	41117379	22	+	27260156	PATU8902	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.7305321770177213	[330]	[1119,893,578,468]	7	hSpCas9	negative selection	8087652
41127620	41127643	22	+	27260156	PATU8902	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.19700375045252563	[422]	[563,562,464,465]	-2	hSpCas9	negative selection	8151915
41126017	41126040	22	-	27260156	PATU8902	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.6356591156547975	[326]	[384,1093,735,593]	6	hSpCas9	negative selection	8151916
41125873	41125896	22	+	27260156	PATU8902	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.5321510281164472	[431]	[1134,659,746,970]	5	hSpCas9	negative selection	8151917
41117333	41117356	22	+	27260156	PANC1	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.8373434160826385	[724]	[1106,1383,1240,807]	9	hSpCas9	negative selection	8208901
41127726	41127749	22	-	27260156	PANC1	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.544801817612409	[456]	[426,766,564,565]	8	hSpCas9	negative selection	8208902
41117356	41117379	22	+	27260156	PANC1	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	1.3100556669117895	[330]	[740,1165,667,380]	9	hSpCas9	negative selection	8208903
41127620	41127643	22	+	27260156	PANC1	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.47594256304542215	[422]	[307,308,232,207]	-6	hSpCas9	negative selection	8273166
41126017	41126040	22	-	27260156	PANC1	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.473875203069456	[326]	[486,552,330,238]	7	hSpCas9	negative selection	8273167
41125873	41125896	22	+	27260156	PANC1	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.560630608262617	[431]	[586,819,418,427]	8	hSpCas9	negative selection	8273168
41117333	41117356	22	+	27260156	PANC0813	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	1.3066340820940663	[724]	[1890,2428,2042,2042]	9	hSpCas9	negative selection	8330152
41127726	41127749	22	-	27260156	PANC0813	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	1.1023821971343575	[456]	[1387,1018,986,1230]	9	hSpCas9	negative selection	8330153
41117356	41117379	22	+	27260156	PANC0813	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	2.042751781724977	[330]	[1572,1888,1230,1701]	9	hSpCas9	negative selection	8330154
41127620	41127643	22	+	27260156	PANC0813	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	0.03444279141010413	[422]	[414,645,581,389]	0	hSpCas9	negative selection	8394417
41126017	41126040	22	-	27260156	PANC0813	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	1.0254980153990116	[326]	[838,650,566,1057]	9	hSpCas9	negative selection	8394418
41125873	41125896	22	+	27260156	PANC0813	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.8625183012887727	[431]	[946,1173,992,595]	9	hSpCas9	negative selection	8394419
41117333	41117356	22	+	27260156	RDES	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.09439796098937203	[724]	[695,772,1015,1146]	1	hSpCas9	negative selection	8451403
41127726	41127749	22	-	27260156	RDES	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	-0.029357213395543272	[456]	[460,461,526,627]	0	hSpCas9	negative selection	8451404
41117356	41117379	22	+	27260156	RDES	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.05379586332238939	[330]	[295,352,385,450]	-1	hSpCas9	negative selection	8451405
41127620	41127643	22	+	27260156	RDES	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.6719721757924481	[422]	[218,325,307,388]	-8	hSpCas9	negative selection	8515668
41126017	41126040	22	-	27260156	RDES	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.4779618589815777	[326]	[249,202,243,404]	-7	hSpCas9	negative selection	8515669
41125873	41125896	22	+	27260156	RDES	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	-0.08831313959325145	[431]	[322,540,447,584]	-1	hSpCas9	negative selection	8515670
41117333	41117356	22	+	27260156	PC3	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.5805261331544644	[724]	[956,1010,1495,926]	9	hSpCas9	negative selection	8572654
41127726	41127749	22	-	27260156	PC3	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.3494345839992777	[456]	[356,563,951,638]	7	hSpCas9	negative selection	8572655
41117356	41117379	22	+	27260156	PC3	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.7581682374432944	[330]	[284,493,959,735]	9	hSpCas9	negative selection	8572656
41127620	41127643	22	+	27260156	PC3	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.7302497439101857	[422]	[191,230,392,253]	-9	hSpCas9	negative selection	8636919
41126017	41126040	22	-	27260156	PC3	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.11154668373882337	[326]	[165,284,553,335]	-3	hSpCas9	negative selection	8636920
41125873	41125896	22	+	27260156	PC3	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.15960173500159103	[431]	[264,391,715,710]	3	hSpCas9	negative selection	8636921
41117333	41117356	22	+	27260156	PATU8988T	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.6329572312768603	[724]	[1535,999,860,930]	9	hSpCas9	negative selection	8693905
41127726	41127749	22	-	27260156	PATU8988T	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.4331516685164529	[456]	[585,619,508,679]	7	hSpCas9	negative selection	8693906
41117356	41117379	22	+	27260156	PATU8988T	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.11239380773167751	[330]	[417,321,260,383]	2	hSpCas9	negative selection	8693907
41127620	41127643	22	+	27260156	PATU8988T	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.16868962383332461	[422]	[270,486,200,521]	-3	hSpCas9	negative selection	8758170
41126017	41126040	22	-	27260156	PATU8988T	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.31716137954326235	[326]	[264,297,651,342]	5	hSpCas9	negative selection	8758171
41125873	41125896	22	+	27260156	PATU8988T	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.4910208121768472	[431]	[395,596,404,983]	7	hSpCas9	negative selection	8758172
41117333	41117356	22	+	27260156	T47D	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.27481989781374394	[724]	[955,923,1081,1135]	6	hSpCas9	negative selection	8815156
41127726	41127749	22	-	27260156	T47D	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.21415803726040278	[456]	[575,667,640,578]	4	hSpCas9	negative selection	8815157
41117356	41117379	22	+	27260156	T47D	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.27745012754210385	[330]	[297,302,356,314]	-6	hSpCas9	negative selection	8815158
41127620	41127643	22	+	27260156	T47D	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.40061011148866754	[422]	[428,252,419,401]	-7	hSpCas9	negative selection	8879421
41126017	41126040	22	-	27260156	T47D	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.3079370850943134	[326]	[317,243,314,360]	-6	hSpCas9	negative selection	8879422
41125873	41125896	22	+	27260156	T47D	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.24678755309113398	[431]	[704,496,671,519]	5	hSpCas9	negative selection	8879423
41117333	41117356	22	+	27260156	SU8686	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.7116206129163192	[724]	[991,1012,1186,1622]	9	hSpCas9	negative selection	8936407
41127726	41127749	22	-	27260156	SU8686	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.31914796009265267	[456]	[452,485,607,766]	5	hSpCas9	negative selection	8936408
41117356	41117379	22	+	27260156	SU8686	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.8744123109654396	[330]	[511,414,781,757]	9	hSpCas9	negative selection	8936409
41127620	41127643	22	+	27260156	SU8686	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.13295888782086077	[422]	[324,317,406,513]	-2	hSpCas9	negative selection	9000672
41126017	41126040	22	-	27260156	SU8686	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.2281504827021803	[326]	[397,365,331,425]	4	hSpCas9	negative selection	9000673
41125873	41125896	22	+	27260156	SU8686	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.5523705702549453	[431]	[543,616,748,608]	8	hSpCas9	negative selection	9000674
41117333	41117356	22	+	27260156	SKES1	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.2513174097208195	[724]	[1036,939,537,946]	5	hSpCas9	negative selection	9057658
41127726	41127749	22	-	27260156	SKES1	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	-0.027903362336559018	[456]	[490,493,409,405]	0	hSpCas9	negative selection	9057659
41117356	41117379	22	+	27260156	SKES1	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	-0.22881248569520773	[330]	[318,285,313,217]	-5	hSpCas9	negative selection	9057660
41127620	41127643	22	+	27260156	SKES1	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.6241196469388217	[422]	[450,307,190,182]	-8	hSpCas9	negative selection	9121923
41126017	41126040	22	-	27260156	SKES1	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.03609543619019673	[326]	[403,363,262,262]	-1	hSpCas9	negative selection	9121924
41125873	41125896	22	+	27260156	SKES1	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.16762558121971552	[431]	[539,518,462,427]	3	hSpCas9	negative selection	9121925
41117333	41117356	22	+	27260156	TOV112D	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.2957848329497853	[724]	[731,1646,665,696]	5	hSpCas9	negative selection	9178909
41127726	41127749	22	-	27260156	TOV112D	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.11352403429022671	[456]	[524,908,435,221]	2	hSpCas9	negative selection	9178910
41117356	41117379	22	+	27260156	TOV112D	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.1380339726671873	[330]	[230,489,459,298]	2	hSpCas9	negative selection	9178911
41127620	41127643	22	+	27260156	TOV112D	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.404603619951623	[422]	[163,502,340,303]	-7	hSpCas9	negative selection	9243174
41126017	41126040	22	-	27260156	TOV112D	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.07607766467304927	[326]	[388,398,252,355]	1	hSpCas9	negative selection	9243175
41125873	41125896	22	+	27260156	TOV112D	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.3226426368426608	[431]	[810,560,453,369]	6	hSpCas9	negative selection	9243176
41117333	41117356	22	+	27260156	TC71	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.2103083010030541	[724]	[983,930,935,731]	5	hSpCas9	negative selection	9300160
41127726	41127749	22	-	27260156	TC71	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.207466078518795	[456]	[558,554,503,651]	5	hSpCas9	negative selection	9300161
41117356	41117379	22	+	27260156	TC71	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.20988390737507467	[330]	[292,397,576,367]	5	hSpCas9	negative selection	9300162
41127620	41127643	22	+	27260156	TC71	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.728229956804828	[422]	[281,188,279,347]	-9	hSpCas9	negative selection	9364425
41126017	41126040	22	-	27260156	TC71	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.23161462530253718	[326]	[225,404,244,322]	-6	hSpCas9	negative selection	9364426
41125873	41125896	22	+	27260156	TC71	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.020300988961289373	[431]	[430,483,459,506]	0	hSpCas9	negative selection	9364427
41117333	41117356	22	+	27260156	TC32	viability	CTGTCAGAATTGCTGCGATCTGG	EP300	ENSG00000100393	0.3638554524318037	[724]	[793,718,1061,986]	6	hSpCas9	negative selection	9421411
41127726	41127749	22	-	27260156	TC32	viability	CTTGGCAAGACTTGCCTGACTGG	EP300	ENSG00000100393	0.06885282634633584	[456]	[475,289,596,497]	1	hSpCas9	negative selection	9421412
41117356	41117379	22	+	27260156	TC32	viability	TAGTTCCCCTAACCTCAATATGG	EP300	ENSG00000100393	0.1947653137419761	[330]	[236,295,500,436]	3	hSpCas9	negative selection	9421413
41127620	41127643	22	+	27260156	TC32	viability	ATGCTCACAAGTGCCAGCGCCGG	EP300	ENSG00000100393	-0.3966735704392016	[422]	[264,290,394,259]	-6	hSpCas9	negative selection	9485676
41126017	41126040	22	-	27260156	TC32	viability	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.1888975429795029	[326]	[414,298,368,306]	3	hSpCas9	negative selection	9485677
41125873	41125896	22	+	27260156	TC32	viability	ATGAACAACCCCAATCCTTATGG	EP300	ENSG00000100393	0.03795297217517811	[431]	[339,347,463,540]	0	hSpCas9	negative selection	9485678
41093069	41093092	22	-	27869803	HPAFII	viability after 27 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.050724474524977525	[107]	[20,82,NaN]	0	hSpCas9	negative selection	9581051
41117390	41117413	22	-	27869803	HPAFII	viability after 27 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.92281452856158	[415]	[152,83,NaN]	-6	hSpCas9	negative selection	9581052
41126017	41126040	22	-	27869803	HPAFII	viability after 27 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.5580343392556013	[139]	[121,96,NaN]	4	hSpCas9	negative selection	9581053
41127528	41127551	22	+	27869803	HPAFII	viability after 27 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-2.1795494203307126	[140]	[5,24,NaN]	-8	hSpCas9	negative selection	9581054
41131557	41131580	22	-	27869803	HPAFII	viability after 27 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.2980774495320406	[76]	[32,154,NaN]	9	hSpCas9	negative selection	9581055
41137673	41137696	22	-	27869803	HPAFII	viability after 27 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.5413313785214846	[214]	[190,443,NaN]	9	hSpCas9	negative selection	9581056
41093069	41093092	22	-	27869803	HPAFII	viability after 15 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	-0.6796208463522235	[107]	[69,73,NaN]	-6	hSpCas9	negative selection	9663500
41117390	41117413	22	-	27869803	HPAFII	viability after 15 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.962407999642279	[415]	[353,151,NaN]	-7	hSpCas9	negative selection	9663501
41126017	41126040	22	-	27869803	HPAFII	viability after 15 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.0056286020560547545	[139]	[250,86,NaN]	0	hSpCas9	negative selection	9663502
41127528	41127551	22	+	27869803	HPAFII	viability after 15 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-1.5992107117078702	[140]	[41,54,NaN]	-8	hSpCas9	negative selection	9663503
41131557	41131580	22	-	27869803	HPAFII	viability after 15 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.9303071188582656	[76]	[190,136,NaN]	8	hSpCas9	negative selection	9663504
41137673	41137696	22	-	27869803	HPAFII	viability after 15 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	0.7064834386942614	[214]	[307,419,NaN]	7	hSpCas9	negative selection	9663505
41093069	41093092	22	-	27869803	ASPC1	viability after 36 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	1.878025439196771	[190]	[542,91,154]	9	hSpCas9	negative selection	9745949
41117390	41117413	22	-	27869803	ASPC1	viability after 36 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	0.7805496551079466	[917]	[907,286,502]	7	hSpCas9	negative selection	9745950
41126017	41126040	22	-	27869803	ASPC1	viability after 36 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.8430246068573879	[401]	[365,238,178]	7	hSpCas9	negative selection	9745951
41127528	41127551	22	+	27869803	ASPC1	viability after 36 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	0.5756143490979465	[292]	[117,67,241]	6	hSpCas9	negative selection	9745952
41131557	41131580	22	-	27869803	ASPC1	viability after 36 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	0.6760317391720406	[398]	[151,172,308]	6	hSpCas9	negative selection	9745953
41137673	41137696	22	-	27869803	ASPC1	viability after 36 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.06871899779900115	[550]	[378,223,11]	0	hSpCas9	negative selection	9745954
41093069	41093092	22	-	27869803	PATU8988S	viability after 35 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.12316897236675883	[137]	[74,45,NaN]	1	hSpCas9	negative selection	9828398
41117390	41117413	22	-	27869803	PATU8988S	viability after 35 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-1.033441791262904	[782]	[181,125,NaN]	-7	hSpCas9	negative selection	9828399
41126017	41126040	22	-	27869803	PATU8988S	viability after 35 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.14186040713441617	[340]	[113,134,NaN]	-1	hSpCas9	negative selection	9828400
41127528	41127551	22	+	27869803	PATU8988S	viability after 35 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-1.4128556469937565	[257]	[49,27,NaN]	-8	hSpCas9	negative selection	9828401
41131557	41131580	22	-	27869803	PATU8988S	viability after 35 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.5436258507631132	[392]	[146,69,NaN]	-5	hSpCas9	negative selection	9828402
41137673	41137696	22	-	27869803	PATU8988S	viability after 35 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-0.5647309371889446	[469]	[117,137,NaN]	-5	hSpCas9	negative selection	9828403
41093069	41093092	22	-	27869803	PATU8988S	viability after 31 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.2098437325365281	[137]	[71,52,NaN]	2	hSpCas9	negative selection	9910847
41117390	41117413	22	-	27869803	PATU8988S	viability after 31 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-0.6856118552823929	[782]	[183,206,NaN]	-6	hSpCas9	negative selection	9910848
41126017	41126040	22	-	27869803	PATU8988S	viability after 31 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	-0.4278160405304362	[340]	[97,104,NaN]	-5	hSpCas9	negative selection	9910849
41127528	41127551	22	+	27869803	PATU8988S	viability after 31 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-1.4460737069359284	[257]	[24,53,NaN]	-8	hSpCas9	negative selection	9910850
41131557	41131580	22	-	27869803	PATU8988S	viability after 31 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	-0.77277240818902	[392]	[85,98,NaN]	-7	hSpCas9	negative selection	9910851
41137673	41137696	22	-	27869803	PATU8988S	viability after 31 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	-1.3890121606019608	[469]	[60,84,NaN]	-8	hSpCas9	negative selection	9910852
41093069	41093092	22	-	27869803	HPAFII	viability after 35 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.31407676581247235	[107]	[11,130,NaN]	2	hSpCas9	negative selection	9993296
41117390	41117413	22	-	27869803	HPAFII	viability after 35 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-1.2246618133852194	[415]	[83,96,NaN]	-6	hSpCas9	negative selection	9993297
41126017	41126040	22	-	27869803	HPAFII	viability after 35 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.3984492056034104	[139]	[107,76,NaN]	2	hSpCas9	negative selection	9993298
41127528	41127551	22	+	27869803	HPAFII	viability after 35 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-2.2855879908361922	[140]	[0,29,NaN]	-8	hSpCas9	negative selection	9993299
41131557	41131580	22	-	27869803	HPAFII	viability after 35 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.7428802502676886	[76]	[10,264,NaN]	9	hSpCas9	negative selection	9993300
41137673	41137696	22	-	27869803	HPAFII	viability after 35 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.7013884907117898	[214]	[59,684,NaN]	9	hSpCas9	negative selection	9993301
41093069	41093092	22	-	27869803	HPAFII	viability after 31 days	ATCGCTGGCGGACGCCGAGAGGG	EP300	ENSG00000100393	0.15621500074435524	[107]	[34,102,NaN]	1	hSpCas9	negative selection	10075745
41117390	41117413	22	-	27869803	HPAFII	viability after 31 days	TGGCTGGCCATGACTTGACCTGG	EP300	ENSG00000100393	-1.3393681158362571	[415]	[86,97,NaN]	-7	hSpCas9	negative selection	10075746
41126017	41126040	22	-	27869803	HPAFII	viability after 31 days	ATGTTGGGCATTCCTCCACCAGG	EP300	ENSG00000100393	0.3090913978816714	[139]	[104,88,NaN]	2	hSpCas9	negative selection	10075747
41127528	41127551	22	+	27869803	HPAFII	viability after 31 days	GACTCCAGTTGCCCAAGGGATGG	EP300	ENSG00000100393	-2.779038306390722	[140]	[0,22,NaN]	-8	hSpCas9	negative selection	10075748
41131557	41131580	22	-	27869803	HPAFII	viability after 31 days	GCTGGTTCTTTGCTTGCACCTGG	EP300	ENSG00000100393	1.7674482424736682	[76]	[26,277,NaN]	9	hSpCas9	negative selection	10075749
41137673	41137696	22	-	27869803	HPAFII	viability after 31 days	AGGACCCAGGGAGGGCACACTGG	EP300	ENSG00000100393	1.2008537262919647	[214]	[173,389,NaN]	8	hSpCas9	negative selection	10075750
41150076	41150099	22	-	28162770	P31FUJ	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.0844794574572774	[313]	[173]	-6	hSpCas9	negative selection	10150353
41150169	41150192	22	-	28162770	P31FUJ	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-2.2247648853489603	[357]	[89]	-8	hSpCas9	negative selection	10150354
41117243	41117266	22	+	28162770	P31FUJ	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.6882539721391305	[180]	[32]	-9	hSpCas9	negative selection	10150355
41117485	41117508	22	+	28162770	P31FUJ	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.33019896720895825	[336]	[314]	-3	hSpCas9	negative selection	10150356
41125918	41125941	22	+	28162770	P31FUJ	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.7986558821878302	[224]	[75]	-8	hSpCas9	negative selection	10150357
41131539	41131562	22	+	28162770	P31FUJ	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-0.9132607023638943	[483]	[301]	-6	hSpCas9	negative selection	10150358
41141059	41141082	22	-	28162770	P31FUJ	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.7688551046545884	[173]	[59]	-8	hSpCas9	negative selection	10150359
41149839	41149862	22	-	28162770	P31FUJ	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.011138233000445086	[282]	[329]	0	hSpCas9	negative selection	10150360
41149875	41149898	22	-	28162770	P31FUJ	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.40987063524133627	[328]	[290]	-4	hSpCas9	negative selection	10150361
41149959	41149982	22	-	28162770	P31FUJ	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.28303650693451504	[262]	[253]	-3	hSpCas9	negative selection	10150362
41150076	41150099	22	-	28162770	TF1	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10319719
41150169	41150192	22	-	28162770	TF1	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10319720
41117243	41117266	22	+	28162770	TF1	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10319721
41117485	41117508	22	+	28162770	TF1	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10319722
41125918	41125941	22	+	28162770	TF1	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10319723
41131539	41131562	22	+	28162770	TF1	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10319724
41141059	41141082	22	-	28162770	TF1	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10319725
41149839	41149862	22	-	28162770	TF1	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10319726
41149875	41149898	22	-	28162770	TF1	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10319727
41149959	41149982	22	-	28162770	TF1	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10319728
41150076	41150099	22	-	28162770	SKM1	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-2.76953427812787	[80]	[20]	-9	hSpCas9	negative selection	10489085
41150169	41150192	22	-	28162770	SKM1	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.519973160572348	[72]	[44]	-7	hSpCas9	negative selection	10489086
41117243	41117266	22	+	28162770	SKM1	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-1.6844981742720706	[59]	[32]	-8	hSpCas9	negative selection	10489087
41117485	41117508	22	+	28162770	SKM1	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	0.15333624774372523	[117]	[231]	1	hSpCas9	negative selection	10489088
41125918	41125941	22	+	28162770	SKM1	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.3908445333798847	[88]	[59]	-7	hSpCas9	negative selection	10489089
41131539	41131562	22	+	28162770	SKM1	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.0489668491482778	[157]	[134]	-6	hSpCas9	negative selection	10489090
41141059	41141082	22	-	28162770	SKM1	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.687072117935897	[50]	[27]	-8	hSpCas9	negative selection	10489091
41149839	41149862	22	-	28162770	SKM1	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.6112346018051847	[88]	[102]	-5	hSpCas9	negative selection	10489092
41149875	41149898	22	-	28162770	SKM1	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.0614676327173949	[84]	[71]	-6	hSpCas9	negative selection	10489093
41149959	41149982	22	-	28162770	SKM1	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.48857796429681377	[49]	[62]	-4	hSpCas9	negative selection	10489094
41150076	41150099	22	-	28162770	SKM1	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-2.76953427812787	[80]	[20]	-9	hSpCas9	negative selection	10658451
41150169	41150192	22	-	28162770	SKM1	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.519973160572348	[72]	[44]	-7	hSpCas9	negative selection	10658452
41117243	41117266	22	+	28162770	SKM1	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-1.6844981742720706	[59]	[32]	-8	hSpCas9	negative selection	10658453
41117485	41117508	22	+	28162770	SKM1	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	0.15333624774372523	[117]	[231]	1	hSpCas9	negative selection	10658454
41125918	41125941	22	+	28162770	SKM1	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.3908445333798847	[88]	[59]	-7	hSpCas9	negative selection	10658455
41131539	41131562	22	+	28162770	SKM1	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.0489668491482778	[157]	[134]	-6	hSpCas9	negative selection	10658456
41141059	41141082	22	-	28162770	SKM1	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.687072117935897	[50]	[27]	-8	hSpCas9	negative selection	10658457
41149839	41149862	22	-	28162770	SKM1	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.6112346018051847	[88]	[102]	-5	hSpCas9	negative selection	10658458
41149875	41149898	22	-	28162770	SKM1	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.0614676327173949	[84]	[71]	-6	hSpCas9	negative selection	10658459
41149959	41149982	22	-	28162770	SKM1	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.48857796429681377	[49]	[62]	-4	hSpCas9	negative selection	10658460
41150076	41150099	22	-	28162770	PL21	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.7528629059735104	[301]	[38]	-8	hSpCas9	negative selection	10827817
41150169	41150192	22	-	28162770	PL21	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.9794679403503315	[298]	[32]	-8	hSpCas9	negative selection	10827818
41117243	41117266	22	+	28162770	PL21	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.4437165752854044	[249]	[19]	-9	hSpCas9	negative selection	10827819
41117485	41117508	22	+	28162770	PL21	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.47173095145500127	[324]	[101]	-3	hSpCas9	negative selection	10827820
41125918	41125941	22	+	28162770	PL21	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-3.86287018303648	[233]	[6]	-9	hSpCas9	negative selection	10827821
41131539	41131562	22	+	28162770	PL21	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.7529739978798442	[665]	[85]	-8	hSpCas9	negative selection	10827822
41141059	41141082	22	-	28162770	PL21	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-4.066646926205582	[153]	[3]	-9	hSpCas9	negative selection	10827823
41149839	41149862	22	-	28162770	PL21	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-3.2193992770244644	[213]	[9]	-9	hSpCas9	negative selection	10827824
41149875	41149898	22	-	28162770	PL21	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.2542387764216916	[284]	[51]	-7	hSpCas9	negative selection	10827825
41149959	41149982	22	-	28162770	PL21	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	0.2853869011078311	[114]	[60]	2	hSpCas9	negative selection	10827826
41150076	41150099	22	-	28162770	P31FUJ	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.0844794574572774	[313]	[173]	-6	hSpCas9	negative selection	10997183
41150169	41150192	22	-	28162770	P31FUJ	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-2.2247648853489603	[357]	[89]	-8	hSpCas9	negative selection	10997184
41117243	41117266	22	+	28162770	P31FUJ	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.6882539721391305	[180]	[32]	-9	hSpCas9	negative selection	10997185
41117485	41117508	22	+	28162770	P31FUJ	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.33019896720895825	[336]	[314]	-3	hSpCas9	negative selection	10997186
41125918	41125941	22	+	28162770	P31FUJ	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.7986558821878302	[224]	[75]	-8	hSpCas9	negative selection	10997187
41131539	41131562	22	+	28162770	P31FUJ	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-0.9132607023638943	[483]	[301]	-6	hSpCas9	negative selection	10997188
41141059	41141082	22	-	28162770	P31FUJ	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.7688551046545884	[173]	[59]	-8	hSpCas9	negative selection	10997189
41149839	41149862	22	-	28162770	P31FUJ	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.011138233000445086	[282]	[329]	0	hSpCas9	negative selection	10997190
41149875	41149898	22	-	28162770	P31FUJ	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.40987063524133627	[328]	[290]	-4	hSpCas9	negative selection	10997191
41149959	41149982	22	-	28162770	P31FUJ	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.28303650693451504	[262]	[253]	-3	hSpCas9	negative selection	10997192
41150076	41150099	22	-	28162770	OCIAML5	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.5514070927302859	[163]	[100]	-7	hSpCas9	negative selection	11166549
41150169	41150192	22	-	28162770	OCIAML5	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-2.267104070142841	[151]	[56]	-8	hSpCas9	negative selection	11166550
41117243	41117266	22	+	28162770	OCIAML5	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	0.0715825430058882	[96]	[183]	0	hSpCas9	negative selection	11166551
41117485	41117508	22	+	28162770	OCIAML5	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	0.46357526117593406	[183]	[457]	4	hSpCas9	negative selection	11166552
41125918	41125941	22	+	28162770	OCIAML5	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-0.5625599536690121	[143]	[175]	-4	hSpCas9	negative selection	11166553
41131539	41131562	22	+	28162770	OCIAML5	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	0.8267323158920856	[247]	[793]	7	hSpCas9	negative selection	11166554
41141059	41141082	22	-	28162770	OCIAML5	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	0.7045672067986648	[119]	[352]	6	hSpCas9	negative selection	11166555
41149839	41149862	22	-	28162770	OCIAML5	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	0.25785112121403847	[119]	[258]	2	hSpCas9	negative selection	11166556
41149875	41149898	22	-	28162770	OCIAML5	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.5202981533490815	[262]	[330]	-4	hSpCas9	negative selection	11166557
41149959	41149982	22	-	28162770	OCIAML5	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.051375379087403694	[92]	[161]	0	hSpCas9	negative selection	11166558
41150076	41150099	22	-	28162770	EOL1	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-0.8378404194755783	[457]	[134]	-5	hSpCas9	negative selection	11335915
41150169	41150192	22	-	28162770	EOL1	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-2.7014419974106767	[320]	[25]	-9	hSpCas9	negative selection	11335916
41117243	41117266	22	+	28162770	EOL1	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-4.123205359877834	[429]	[12]	-9	hSpCas9	negative selection	11335917
41117485	41117508	22	+	28162770	EOL1	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.7609842221946383	[697]	[216]	-5	hSpCas9	negative selection	11335918
41125918	41125941	22	+	28162770	EOL1	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-4.703188752840913	[444]	[8]	-9	hSpCas9	negative selection	11335919
41131539	41131562	22	+	28162770	EOL1	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.4601160786647904	[1033]	[197]	-7	hSpCas9	negative selection	11335920
41141059	41141082	22	-	28162770	EOL1	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-3.599014184486479	[206]	[8]	-9	hSpCas9	negative selection	11335921
41149839	41149862	22	-	28162770	EOL1	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-2.16488731201141	[365]	[42]	-8	hSpCas9	negative selection	11335922
41149875	41149898	22	-	28162770	EOL1	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-2.3761117065631763	[403]	[40]	-8	hSpCas9	negative selection	11335923
41149959	41149982	22	-	28162770	EOL1	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.6334476815503522	[211]	[71]	-4	hSpCas9	negative selection	11335924
41150076	41150099	22	-	28162770	MOLM13	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.9131046542073011	[348]	[66]	-7	hSpCas9	negative selection	11505281
41150169	41150192	22	-	28162770	MOLM13	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-3.817512837317669	[311]	[15]	-9	hSpCas9	negative selection	11505282
41117243	41117266	22	+	28162770	MOLM13	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	0.0808662584353316	[288]	[220]	0	hSpCas9	negative selection	11505283
41117485	41117508	22	+	28162770	MOLM13	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.5001677259526669	[535]	[273]	-3	hSpCas9	negative selection	11505284
41125918	41125941	22	+	28162770	MOLM13	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-0.9577173594444522	[273]	[101]	-5	hSpCas9	negative selection	11505285
41131539	41131562	22	+	28162770	MOLM13	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.3678812226771118	[845]	[236]	-6	hSpCas9	negative selection	11505286
41141059	41141082	22	-	28162770	MOLM13	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.2690762126216273	[249]	[74]	-6	hSpCas9	negative selection	11505287
41149839	41149862	22	-	28162770	MOLM13	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-1.7317829632917856	[440]	[95]	-7	hSpCas9	negative selection	11505288
41149875	41149898	22	-	28162770	MOLM13	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.4991123428979642	[388]	[198]	-3	hSpCas9	negative selection	11505289
41149959	41149982	22	-	28162770	MOLM13	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-1.3261071576580061	[214]	[61]	-6	hSpCas9	negative selection	11505290
41150076	41150099	22	-	28162770	HEL	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.694496515674854	[378]	[74]	-7	hSpCas9	negative selection	11674647
41150169	41150192	22	-	28162770	HEL	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-3.281025582172558	[257]	[16]	-9	hSpCas9	negative selection	11674648
41117243	41117266	22	+	28162770	HEL	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-0.19571730734498702	[210]	[117]	-1	hSpCas9	negative selection	11674649
41117485	41117508	22	+	28162770	HEL	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.2203512237852937	[441]	[242]	-1	hSpCas9	negative selection	11674650
41125918	41125941	22	+	28162770	HEL	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.0233220940150374	[310]	[97]	-6	hSpCas9	negative selection	11674651
41131539	41131562	22	+	28162770	HEL	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-0.2715312939737593	[685]	[363]	-2	hSpCas9	negative selection	11674652
41141059	41141082	22	-	28162770	HEL	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.2492784871266314	[192]	[51]	-6	hSpCas9	negative selection	11674653
41149839	41149862	22	-	28162770	HEL	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.4153641225632114	[303]	[145]	-3	hSpCas9	negative selection	11674654
41149875	41149898	22	-	28162770	HEL	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.8331308114989173	[330]	[118]	-5	hSpCas9	negative selection	11674655
41149959	41149982	22	-	28162770	HEL	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-1.4977423915494734	[193]	[43]	-7	hSpCas9	negative selection	11674656
41150076	41150099	22	-	28162770	MV411	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-2.8084156839507424	[315]	[37]	-9	hSpCas9	negative selection	11844013
41150169	41150192	22	-	28162770	MV411	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-2.9155010203434304	[205]	[22]	-9	hSpCas9	negative selection	11844014
41117243	41117266	22	+	28162770	MV411	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-4.264674384530699	[250]	[10]	-9	hSpCas9	negative selection	11844015
41117485	41117508	22	+	28162770	MV411	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.13541954274691892	[398]	[305]	-1	hSpCas9	negative selection	11844016
41125918	41125941	22	+	28162770	MV411	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-2.554181001725684	[250]	[35]	-8	hSpCas9	negative selection	11844017
41131539	41131562	22	+	28162770	MV411	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.714594599018204	[599]	[153]	-8	hSpCas9	negative selection	11844018
41141059	41141082	22	-	28162770	MV411	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-0.9646129263322136	[138]	[59]	-6	hSpCas9	negative selection	11844019
41149839	41149862	22	-	28162770	MV411	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.45465758353637853	[217]	[133]	-3	hSpCas9	negative selection	11844020
41149875	41149898	22	-	28162770	MV411	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.5327812413373147	[236]	[68]	-7	hSpCas9	negative selection	11844021
41149959	41149982	22	-	28162770	MV411	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	0.014552755628685105	[160]	[136]	0	hSpCas9	negative selection	11844022
41150076	41150099	22	-	28162770	MONOMAC1	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.5874963236177315	[193]	[73]	-8	hSpCas9	negative selection	12013379
41150169	41150192	22	-	28162770	MONOMAC1	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-0.6922446950223811	[147]	[104]	-5	hSpCas9	negative selection	12013380
41117243	41117266	22	+	28162770	MONOMAC1	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-3.065792313781301	[167]	[22]	-9	hSpCas9	negative selection	12013381
41117485	41117508	22	+	28162770	MONOMAC1	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-1.0389720008273025	[189]	[105]	-7	hSpCas9	negative selection	12013382
41125918	41125941	22	+	28162770	MONOMAC1	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-2.7902669637643105	[174]	[28]	-9	hSpCas9	negative selection	12013383
41131539	41131562	22	+	28162770	MONOMAC1	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-2.4117756958525662	[375]	[80]	-9	hSpCas9	negative selection	12013384
41141059	41141082	22	-	28162770	MONOMAC1	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-1.7550323001804407	[105]	[35]	-8	hSpCas9	negative selection	12013385
41149839	41149862	22	-	28162770	MONOMAC1	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-2.0126122759221263	[175]	[49]	-8	hSpCas9	negative selection	12013386
41149875	41149898	22	-	28162770	MONOMAC1	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-0.9422229480307283	[175]	[104]	-6	hSpCas9	negative selection	12013387
41149959	41149982	22	-	28162770	MONOMAC1	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.9293410638558968	[102]	[61]	-6	hSpCas9	negative selection	12013388
41150076	41150099	22	-	28162770	OCIAML2	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-1.614365302703611	[57]	[104]	-7	hSpCas9	negative selection	12182745
41150169	41150192	22	-	28162770	OCIAML2	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.9012641795720235	[30]	[45]	-8	hSpCas9	negative selection	12182746
41117243	41117266	22	+	28162770	OCIAML2	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-1.6715425191681577	[49]	[86]	-7	hSpCas9	negative selection	12182747
41117485	41117508	22	+	28162770	OCIAML2	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.007455804919047182	[69]	[385]	0	hSpCas9	negative selection	12182748
41125918	41125941	22	+	28162770	OCIAML2	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-3.311932079223103	[42]	[23]	-9	hSpCas9	negative selection	12182749
41131539	41131562	22	+	28162770	OCIAML2	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.4226244523313287	[132]	[274]	-7	hSpCas9	negative selection	12182750
41141059	41141082	22	-	28162770	OCIAML2	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-2.515023944600615	[32]	[31]	-8	hSpCas9	negative selection	12182751
41149839	41149862	22	-	28162770	OCIAML2	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-1.16512727826791	[52]	[130]	-6	hSpCas9	negative selection	12182752
41149875	41149898	22	-	28162770	OCIAML2	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-2.040945549998916	[48]	[65]	-8	hSpCas9	negative selection	12182753
41149959	41149982	22	-	28162770	OCIAML2	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.19761133083574522	[11]	[57]	-2	hSpCas9	negative selection	12182754
41150076	41150099	22	-	28162770	OCIAML3	viability	GAAGGTGCAGCAGGAAGTGAAGG	EP300	ENSG00000100393	-0.8778006063247543	[83]	[137]	-6	hSpCas9	negative selection	12352111
41150169	41150192	22	-	28162770	OCIAML3	viability	GCAGGCTGCGGAGGAAGCAGCGG	EP300	ENSG00000100393	-1.2488721542754755	[73]	[93]	-7	hSpCas9	negative selection	12352112
41117243	41117266	22	+	28162770	OCIAML3	viability	ACAGAATTGGGACTAACCAATGG	EP300	ENSG00000100393	-2.0269670476002695	[53]	[39]	-8	hSpCas9	negative selection	12352113
41117485	41117508	22	+	28162770	OCIAML3	viability	GACTTCTCCCAACATGGGGATGG	EP300	ENSG00000100393	-0.16710998583525838	[105]	[284]	-1	hSpCas9	negative selection	12352114
41125918	41125941	22	+	28162770	OCIAML3	viability	GGACAGCAGATTGGAGCCAGTGG	EP300	ENSG00000100393	-1.774579885965984	[50]	[44]	-8	hSpCas9	negative selection	12352115
41131539	41131562	22	+	28162770	OCIAML3	viability	TCAGATGCCGACACAACCCCAGG	EP300	ENSG00000100393	-1.4944719667732487	[153]	[164]	-7	hSpCas9	negative selection	12352116
41141059	41141082	22	-	28162770	OCIAML3	viability	AGATTTTCTCAGCTAGAAGGTGG	EP300	ENSG00000100393	-2.2087174844393713	[48]	[31]	-8	hSpCas9	negative selection	12352117
41149839	41149862	22	-	28162770	OCIAML3	viability	AGAGCTGGTTGAGGAAGCTGGGG	EP300	ENSG00000100393	-0.7257975128797043	[62]	[114]	-5	hSpCas9	negative selection	12352118
41149875	41149898	22	-	28162770	OCIAML3	viability	GTACGACTAGGTACAGGCGAGGG	EP300	ENSG00000100393	-1.2973906339659882	[91]	[112]	-7	hSpCas9	negative selection	12352119
41149959	41149982	22	-	28162770	OCIAML3	viability	GGAGGTGTAGGAACAGGGGCTGG	EP300	ENSG00000100393	-0.6141855222617935	[35]	[70]	-5	hSpCas9	negative selection	12352120