Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2059
• Symbol: EPS8
• Description: EGFR pathway substrate 8, signaling adaptor

DataSource: http://genomecrispr.dkfz.de/#!/results/EPS8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15631445	15631468	12	-	26472758	Jiyoye	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	51196
15640820	15640843	12	-	26472758	Jiyoye	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-0.058488190842938326	[173]	[125]	0	hSpCas9	negative selection	51197
15666470	15666493	12	-	26472758	Jiyoye	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.8617412449713546	[26]	[73]	8	hSpCas9	negative selection	51198
15666457	15666480	12	-	26472758	Jiyoye	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.5074331272634819	[163]	[86]	-4	hSpCas9	negative selection	51199
15654274	15654297	12	-	26472758	Jiyoye	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.28439830984631853	[364]	[225]	-2	hSpCas9	negative selection	51200
15647226	15647249	12	-	26472758	Jiyoye	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.4390242475452134	[223]	[228]	3	hSpCas9	negative selection	51201
15660613	15660636	12	-	26472758	Jiyoye	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-1.815217039830575	[13]	[2]	-8	hSpCas9	negative selection	51202
15654177	15654200	12	-	26472758	Jiyoye	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.8825133910525313	[81]	[113]	6	hSpCas9	negative selection	51203
15647175	15647198	12	-	26472758	Jiyoye	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.003504137176974176	[294]	[222]	0	hSpCas9	negative selection	51204
15647158	15647181	12	+	26472758	Jiyoye	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	-0.2018727377395959	[452]	[296]	-1	hSpCas9	negative selection	51205
15631445	15631468	12	-	26472758	KBM7	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	1.0816969781589814	[3,3]	[3,3]	9	hSpCas9	negative selection	242314
15640820	15640843	12	-	26472758	KBM7	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.7768708796907102	[629,550]	[393,546]	8	hSpCas9	negative selection	242315
15666470	15666493	12	-	26472758	KBM7	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.3978713569690802	[299,272]	[271,92]	4	hSpCas9	negative selection	242316
15666457	15666480	12	-	26472758	KBM7	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.20536812341995275	[729,757]	[409,211]	-2	hSpCas9	negative selection	242317
15654274	15654297	12	-	26472758	KBM7	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.13221706147665824	[1336,1071]	[438,579]	-1	hSpCas9	negative selection	242318
15647226	15647249	12	-	26472758	KBM7	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.5096106912396222	[917,557]	[472,493]	5	hSpCas9	negative selection	242319
15660613	15660636	12	-	26472758	KBM7	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.267673643409589	[38,26]	[0,33]	2	hSpCas9	negative selection	242320
15654177	15654200	12	-	26472758	KBM7	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.05848657780224803	[568,669]	[300,312]	0	hSpCas9	negative selection	242321
15647175	15647198	12	-	26472758	KBM7	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.4259340897086983	[1066,755]	[671,475]	4	hSpCas9	negative selection	242322
15647158	15647181	12	+	26472758	KBM7	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.8666167219392467	[1381,954]	[922,1045]	8	hSpCas9	negative selection	242323
15631445	15631468	12	-	26472758	Raji	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	2.2593866288186497	[8]	[9]	9	hSpCas9	negative selection	433432
15640820	15640843	12	-	26472758	Raji	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-0.13617349596089068	[411]	[86]	-1	hSpCas9	negative selection	433433
15666470	15666493	12	-	26472758	Raji	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.21429873929011167	[155]	[41]	2	hSpCas9	negative selection	433434
15666457	15666480	12	-	26472758	Raji	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.5950018270824621	[370]	[56]	-5	hSpCas9	negative selection	433435
15654274	15654297	12	-	26472758	Raji	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.4939926263259261	[409]	[133]	5	hSpCas9	negative selection	433436
15647226	15647249	12	-	26472758	Raji	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.614184013336408	[334]	[118]	6	hSpCas9	negative selection	433437
15660613	15660636	12	-	26472758	Raji	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-1.7995070602349195	[14]	[0]	-8	hSpCas9	negative selection	433438
15654177	15654200	12	-	26472758	Raji	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.21309297654471449	[170]	[45]	2	hSpCas9	negative selection	433439
15647175	15647198	12	-	26472758	Raji	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.9451121064747225	[422]	[188]	8	hSpCas9	negative selection	433440
15647158	15647181	12	+	26472758	Raji	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.012541163757662677	[832]	[194]	0	hSpCas9	negative selection	433441
15631445	15631468	12	-	26472758	K562	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	0.24441872766644668	[14]	[14]	1	hSpCas9	negative selection	624550
15640820	15640843	12	-	26472758	K562	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.48127651094116725	[481]	[567]	4	hSpCas9	negative selection	624551
15666470	15666493	12	-	26472758	K562	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.3503910963195436	[163]	[352]	9	hSpCas9	negative selection	624552
15666457	15666480	12	-	26472758	K562	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.8401147825452208	[614]	[289]	-5	hSpCas9	negative selection	624553
15654274	15654297	12	-	26472758	K562	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.08910832467203811	[1018]	[914]	0	hSpCas9	negative selection	624554
15647226	15647249	12	-	26472758	K562	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.4277540612731683	[582]	[661]	3	hSpCas9	negative selection	624555
15660613	15660636	12	-	26472758	K562	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	3.424327817681381	[15]	[144]	9	hSpCas9	negative selection	624556
15654177	15654200	12	-	26472758	K562	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.15313822067715743	[472]	[443]	1	hSpCas9	negative selection	624557
15647175	15647198	12	-	26472758	K562	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.6672757314045901	[689]	[924]	5	hSpCas9	negative selection	624558
15647158	15647181	12	+	26472758	K562	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.3750439190270185	[1012]	[1108]	3	hSpCas9	negative selection	624559
15650846	15650869	12	-	26627737	DLD1	viability	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.6020832278277612	[892]	[472,343,446]	6	hSpCas9	negative selection	783181
15654274	15654297	12	-	26627737	DLD1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.1570536889918194	[437]	[127,136,186]	1	hSpCas9	negative selection	783182
15662070	15662093	12	-	26627737	DLD1	viability	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.0026633681143909405	[375]	[192,87,75]	0	hSpCas9	negative selection	783183
15665760	15665783	12	-	26627737	DLD1	viability	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.6493420345005474	[397]	[193,152,230]	6	hSpCas9	negative selection	783184
15666470	15666493	12	-	26627737	DLD1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.4980707420724064	[1012]	[532,248,536]	5	hSpCas9	negative selection	783185
15669793	15669816	12	+	26627737	DLD1	viability	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.10091060138555463	[540]	[189,115,227]	1	hSpCas9	negative selection	783186
15650846	15650869	12	-	26627737	GBM cells	viability after 5 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.46231781024774454	[426]	[286,343]	7	hSpCas9	negative selection	865496
15654274	15654297	12	-	26627737	GBM cells	viability after 5 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.33216078955056316	[249]	[105,106]	-5	hSpCas9	negative selection	865497
15662070	15662093	12	-	26627737	GBM cells	viability after 5 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.04330378422086023	[170]	[60,127]	0	hSpCas9	negative selection	865498
15665760	15665783	12	-	26627737	GBM cells	viability after 5 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.2340249569324428	[283]	[102,155]	-4	hSpCas9	negative selection	865499
15666470	15666493	12	-	26627737	GBM cells	viability after 5 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.02800396227756785	[640]	[368,331]	0	hSpCas9	negative selection	865500
15669793	15669816	12	+	26627737	GBM cells	viability after 5 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.07245012988037675	[265]	[163,135]	1	hSpCas9	negative selection	865501
15650846	15650869	12	-	26627737	GBM cells	viability after 13 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.17791964866658005	[426]	[303,227]	2	hSpCas9	negative selection	947811
15654274	15654297	12	-	26627737	GBM cells	viability after 13 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.06572651255735831	[249]	[165,99]	-1	hSpCas9	negative selection	947812
15662070	15662093	12	-	26627737	GBM cells	viability after 13 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.059420125433608084	[170]	[93,84]	0	hSpCas9	negative selection	947813
15665760	15665783	12	-	26627737	GBM cells	viability after 13 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.3133621392710852	[283]	[139,110]	-4	hSpCas9	negative selection	947814
15666470	15666493	12	-	26627737	GBM cells	viability after 13 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.14531404365598632	[640]	[441,337]	1	hSpCas9	negative selection	947815
15669793	15669816	12	+	26627737	GBM cells	viability after 13 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.3610663445728207	[265]	[234,144]	4	hSpCas9	negative selection	947816
15650846	15650869	12	-	26627737	GBM cells	viability after 21 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.18744566430078158	[426]	[271,256]	2	hSpCas9	negative selection	1030126
15654274	15654297	12	-	26627737	GBM cells	viability after 21 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.22978271280796872	[249]	[119,111]	-2	hSpCas9	negative selection	1030127
15662070	15662093	12	-	26627737	GBM cells	viability after 21 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.2708326745753382	[170]	[76,76]	-2	hSpCas9	negative selection	1030128
15665760	15665783	12	-	26627737	GBM cells	viability after 21 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.1861822415501822	[283]	[132,137]	-2	hSpCas9	negative selection	1030129
15666470	15666493	12	-	26627737	GBM cells	viability after 21 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.4582938596300832	[640]	[502,455]	5	hSpCas9	negative selection	1030130
15669793	15669816	12	+	26627737	GBM cells	viability after 21 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.5726962970339176	[265]	[239,191]	6	hSpCas9	negative selection	1030131
15650846	15650869	12	-	26627737	RPE1	viability after 9 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.7691059360181777	[1555]	[641,1072]	5	hSpCas9	negative selection	1112441
15654274	15654297	12	-	26627737	RPE1	viability after 9 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.020578031722557455	[867]	[100,500]	0	hSpCas9	negative selection	1112442
15662070	15662093	12	-	26627737	RPE1	viability after 9 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.8723545915998767	[140]	[189,124]	8	hSpCas9	negative selection	1112443
15665760	15665783	12	-	26627737	RPE1	viability after 9 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	2.142987589559578	[250]	[257,461]	9	hSpCas9	negative selection	1112444
15666470	15666493	12	-	26627737	RPE1	viability after 9 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.8708799399585754	[2866]	[516,456]	-6	hSpCas9	negative selection	1112445
15669793	15669816	12	+	26627737	RPE1	viability after 9 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	-0.3301825310819539	[773]	[190,194]	-2	hSpCas9	negative selection	1112446
15650846	15650869	12	-	26627737	RPE1	viability after 12 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.8290375823531236	[1555]	[696,790]	5	hSpCas9	negative selection	1194756
15654274	15654297	12	-	26627737	RPE1	viability after 12 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.04325597578351223	[867]	[151,304]	0	hSpCas9	negative selection	1194757
15662070	15662093	12	-	26627737	RPE1	viability after 12 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.8422032302718125	[140]	[180,87]	8	hSpCas9	negative selection	1194758
15665760	15665783	12	-	26627737	RPE1	viability after 12 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	2.303698636833369	[250]	[177,496]	9	hSpCas9	negative selection	1194759
15666470	15666493	12	-	26627737	RPE1	viability after 12 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.7433663375910124	[2866]	[497,419]	-5	hSpCas9	negative selection	1194760
15669793	15669816	12	+	26627737	RPE1	viability after 12 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	-0.33800928785280443	[773]	[215,109]	-2	hSpCas9	negative selection	1194761
15650846	15650869	12	-	26627737	RPE1	viability after 15 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.8476975577405094	[1555]	[925,662]	5	hSpCas9	negative selection	1277071
15654274	15654297	12	-	26627737	RPE1	viability after 15 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.07575630724056998	[867]	[177,285]	0	hSpCas9	negative selection	1277072
15662070	15662093	12	-	26627737	RPE1	viability after 15 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.7038621443413247	[140]	[245,17]	8	hSpCas9	negative selection	1277073
15665760	15665783	12	-	26627737	RPE1	viability after 15 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.7741982287416769	[250]	[109,370]	8	hSpCas9	negative selection	1277074
15666470	15666493	12	-	26627737	RPE1	viability after 15 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.8788906609647169	[2866]	[411,468]	-5	hSpCas9	negative selection	1277075
15669793	15669816	12	+	26627737	RPE1	viability after 15 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	-0.601730557681407	[773]	[212,77]	-4	hSpCas9	negative selection	1277076
15650846	15650869	12	-	26627737	RPE1	viability after 18 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.8571385205714476	[1555]	[837,677]	5	hSpCas9	negative selection	1359386
15654274	15654297	12	-	26627737	RPE1	viability after 18 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.6729084919049052	[867]	[71,226]	-4	hSpCas9	negative selection	1359387
15662070	15662093	12	-	26627737	RPE1	viability after 18 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.1568508720057453	[140]	[123,42]	6	hSpCas9	negative selection	1359388
15665760	15665783	12	-	26627737	RPE1	viability after 18 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.218005456346997	[250]	[115,201]	7	hSpCas9	negative selection	1359389
15666470	15666493	12	-	26627737	RPE1	viability after 18 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.9092569794306943	[2866]	[381,443]	-5	hSpCas9	negative selection	1359390
15669793	15669816	12	+	26627737	RPE1	viability after 18 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	-0.45141459460225447	[773]	[203,97]	-3	hSpCas9	negative selection	1359391
15650846	15650869	12	-	26627737	HeLa	viability after 8 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.3995522576368087	[812]	[639,492,315]	3	hSpCas9	negative selection	1441701
15654274	15654297	12	-	26627737	HeLa	viability after 8 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.08441105697749424	[579]	[398,237,120]	-1	hSpCas9	negative selection	1441702
15662070	15662093	12	-	26627737	HeLa	viability after 8 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.5201438005047064	[255]	[193,150,142]	4	hSpCas9	negative selection	1441703
15665760	15665783	12	-	26627737	HeLa	viability after 8 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.16018480138297253	[521]	[218,186,206]	-1	hSpCas9	negative selection	1441704
15666470	15666493	12	-	26627737	HeLa	viability after 8 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.7961685620686356	[819]	[416,922,483]	6	hSpCas9	negative selection	1441705
15669793	15669816	12	+	26627737	HeLa	viability after 8 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	-0.4835456353355507	[422]	[121,141,128]	-5	hSpCas9	negative selection	1441706
15650846	15650869	12	-	26627737	HeLa	viability after 12 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.3632294732702528	[812]	[493,406,399]	3	hSpCas9	negative selection	1524016
15654274	15654297	12	-	26627737	HeLa	viability after 12 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.07542397302231885	[579]	[292,211,180]	0	hSpCas9	negative selection	1524017
15662070	15662093	12	-	26627737	HeLa	viability after 12 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-1.5901575494731404	[255]	[33,0,73]	-9	hSpCas9	negative selection	1524018
15665760	15665783	12	-	26627737	HeLa	viability after 12 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.08345640588186415	[521]	[280,137,200]	0	hSpCas9	negative selection	1524019
15666470	15666493	12	-	26627737	HeLa	viability after 12 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.06203036378500926	[819]	[388,403,263]	0	hSpCas9	negative selection	1524020
15669793	15669816	12	+	26627737	HeLa	viability after 12 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.08459433469254171	[422]	[153,139,265]	0	hSpCas9	negative selection	1524021
15650846	15650869	12	-	26627737	HeLa	viability after 15 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	-0.30437966641113123	[812]	[149,297,364]	-3	hSpCas9	negative selection	1606331
15654274	15654297	12	-	26627737	HeLa	viability after 15 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.305072181134005	[579]	[198,389,286]	2	hSpCas9	negative selection	1606332
15662070	15662093	12	-	26627737	HeLa	viability after 15 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.1337190897904582	[255]	[127,158,50]	1	hSpCas9	negative selection	1606333
15665760	15665783	12	-	26627737	HeLa	viability after 15 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.20512301064428415	[521]	[76,285,191]	-2	hSpCas9	negative selection	1606334
15666470	15666493	12	-	26627737	HeLa	viability after 15 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.599948672456978	[819]	[280,266,102]	-5	hSpCas9	negative selection	1606335
15669793	15669816	12	+	26627737	HeLa	viability after 15 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.12898394979966565	[422]	[144,225,194]	1	hSpCas9	negative selection	1606336
15650846	15650869	12	-	26627737	HeLa	viability after 18 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	-0.2956791590542627	[812]	[101,248,364]	-3	hSpCas9	negative selection	1688646
15654274	15654297	12	-	26627737	HeLa	viability after 18 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.2818348494930346	[579]	[133,310,286]	2	hSpCas9	negative selection	1688647
15662070	15662093	12	-	26627737	HeLa	viability after 18 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.08484245018358827	[255]	[74,135,50]	0	hSpCas9	negative selection	1688648
15665760	15665783	12	-	26627737	HeLa	viability after 18 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-0.1565301119585771	[521]	[54,247,191]	-1	hSpCas9	negative selection	1688649
15666470	15666493	12	-	26627737	HeLa	viability after 18 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.5542369016734163	[819]	[203,218,102]	-5	hSpCas9	negative selection	1688650
15669793	15669816	12	+	26627737	HeLa	viability after 18 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.17778667934600473	[422]	[105,191,194]	1	hSpCas9	negative selection	1688651
15650846	15650869	12	-	26627737	HCT116	viability after 6 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	-0.04536564587271297	[1090]	[142,178]	0	hSpCas9	negative selection	1770961
15654274	15654297	12	-	26627737	HCT116	viability after 6 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.2531124029083448	[1131]	[80,186]	-1	hSpCas9	negative selection	1770962
15662070	15662093	12	-	26627737	HCT116	viability after 6 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	2.8581741219017247	[199]	[615,13]	9	hSpCas9	negative selection	1770963
15665760	15665783	12	-	26627737	HCT116	viability after 6 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.3463572345110166	[448]	[241,144]	7	hSpCas9	negative selection	1770964
15666470	15666493	12	-	26627737	HCT116	viability after 6 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.8439200264594567	[1677]	[213,109]	-5	hSpCas9	negative selection	1770965
15669793	15669816	12	+	26627737	HCT116	viability after 6 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.4914077513528742	[575]	[203,84]	2	hSpCas9	negative selection	1770966
15650846	15650869	12	-	26627737	HCT116	viability after 8 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.7012309591096777	[388]	[383,382,279]	6	hSpCas9	negative selection	1853276
15654274	15654297	12	-	26627737	HCT116	viability after 8 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.5650536004236452	[256]	[215,149,261]	5	hSpCas9	negative selection	1853277
15662070	15662093	12	-	26627737	HCT116	viability after 8 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.9393443417921661	[360]	[167,94,49]	-8	hSpCas9	negative selection	1853278
15665760	15665783	12	-	26627737	HCT116	viability after 8 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.6553190865992605	[181]	[142,124,204]	6	hSpCas9	negative selection	1853279
15666470	15666493	12	-	26627737	HCT116	viability after 8 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.11039649173216382	[863]	[466,455,400]	-1	hSpCas9	negative selection	1853280
15669793	15669816	12	+	26627737	HCT116	viability after 8 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.17743507185487287	[321]	[174,184,240]	2	hSpCas9	negative selection	1853281
15650846	15650869	12	-	26627737	HCT116	viability after 9 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.2521964455902399	[1090]	[332,357]	2	hSpCas9	negative selection	1935591
15654274	15654297	12	-	26627737	HCT116	viability after 9 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-1.2401762260142566	[1131]	[156,104]	-7	hSpCas9	negative selection	1935592
15662070	15662093	12	-	26627737	HCT116	viability after 9 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.202062224767642	[199]	[85,151]	7	hSpCas9	negative selection	1935593
15665760	15665783	12	-	26627737	HCT116	viability after 9 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.784321733906483	[448]	[363,81]	5	hSpCas9	negative selection	1935594
15666470	15666493	12	-	26627737	HCT116	viability after 9 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.40738855265921736	[1677]	[410,279]	-3	hSpCas9	negative selection	1935595
15669793	15669816	12	+	26627737	HCT116	viability after 9 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.1726200827238532	[575]	[293,77]	1	hSpCas9	negative selection	1935596
15650846	15650869	12	-	26627737	HCT116	viability after 12 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.5616937658875787	[388]	[254,370,284]	5	hSpCas9	negative selection	2017906
15654274	15654297	12	-	26627737	HCT116	viability after 12 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.9796677749989262	[256]	[184,341,280]	8	hSpCas9	negative selection	2017907
15662070	15662093	12	-	26627737	HCT116	viability after 12 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.2375208920025848	[360]	[186,141,150]	-2	hSpCas9	negative selection	2017908
15665760	15665783	12	-	26627737	HCT116	viability after 12 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.004199977041687	[181]	[219,229,123]	8	hSpCas9	negative selection	2017909
15666470	15666493	12	-	26627737	HCT116	viability after 12 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.47038357089491245	[863]	[381,310,284]	-5	hSpCas9	negative selection	2017910
15669793	15669816	12	+	26627737	HCT116	viability after 12 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.37351744726914293	[321]	[175,240,244]	4	hSpCas9	negative selection	2017911
15650846	15650869	12	-	26627737	HCT116	viability after 15 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.9928951795669898	[388]	[524,489,329]	8	hSpCas9	negative selection	2100221
15654274	15654297	12	-	26627737	HCT116	viability after 15 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.073288783244392	[256]	[271,342,311]	8	hSpCas9	negative selection	2100222
15662070	15662093	12	-	26627737	HCT116	viability after 15 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.30542671351111683	[360]	[220,139,148]	-3	hSpCas9	negative selection	2100223
15665760	15665783	12	-	26627737	HCT116	viability after 15 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.0832195645856098	[181]	[273,277,119]	8	hSpCas9	negative selection	2100224
15666470	15666493	12	-	26627737	HCT116	viability after 15 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.1759021959249838	[863]	[705,407,584]	1	hSpCas9	negative selection	2100225
15669793	15669816	12	+	26627737	HCT116	viability after 15 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.6634623103095632	[321]	[256,297,318]	6	hSpCas9	negative selection	2100226
15650846	15650869	12	-	26627737	HCT116	viability after 18 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.7600658253078345	[388]	[417,298,235]	6	hSpCas9	negative selection	2182536
15654274	15654297	12	-	26627737	HCT116	viability after 18 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.094096791225543	[256]	[194,325,270]	8	hSpCas9	negative selection	2182537
15662070	15662093	12	-	26627737	HCT116	viability after 18 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	-0.6360435409069343	[360]	[105,96,135]	-5	hSpCas9	negative selection	2182538
15665760	15665783	12	-	26627737	HCT116	viability after 18 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.7581185139822393	[181]	[113,183,145]	6	hSpCas9	negative selection	2182539
15666470	15666493	12	-	26627737	HCT116	viability after 18 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.5635090146442872	[863]	[690,671,478]	5	hSpCas9	negative selection	2182540
15669793	15669816	12	+	26627737	HCT116	viability after 18 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.7847430365576924	[321]	[202,256,348]	6	hSpCas9	negative selection	2182541
15842724	15842747	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGACTGCTTGAGCCCAGG	EPS8	ENSG00000151491	0.7107825170273987	[226,48]	[71,23]	3	dCas9-VP64	positive selection	2383412
15856695	15856718	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCATGCTGGAATACAGTGG	EPS8	ENSG00000151491	1.1601218908602615	[129,33]	[69,6]	4	dCas9-VP64	positive selection	2387684
15843454	15843477	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTGAGCCACCGTGCCAGG	EPS8	ENSG00000151491	-0.21542961903399005	[276,86]	[54,10]	-1	dCas9-VP64	positive selection	2388496
15751312	15751335	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACGCCACTGCACTCCAGCCTGG	EPS8	ENSG00000151491	-0.23120917697478569	[21,115]	[6,17]	-1	dCas9-VP64	positive selection	2389402
15851018	15851041	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTGGGAGGCTGAGGCAGGGGG	EPS8	ENSG00000151491	1.0311422578945828	[46,428]	[158,53]	4	dCas9-VP64	positive selection	2400124
15676215	15676238	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCTGGG	EPS8	ENSG00000151491	0.12883397399525423	[86,65]	[25,8]	0	dCas9-VP64	positive selection	2424637
15789648	15789671	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCGATCAAAGTCGGACCAAGG	EPS8	ENSG00000151491	1.0682490988946858	[72,250]	[119,26]	4	dCas9-VP64	positive selection	2435664
15789714	15789737	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACTAGCAGCCAGGAGGCGCAGG	EPS8	ENSG00000151491	0.9842324056908782	[206,419]	[79,198]	4	dCas9-VP64	positive selection	2435665
15789688	15789711	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTTCCAGAAGTGCCCTAACAGG	EPS8	ENSG00000151491	-1.1169103882193734	[10,83]	[3,4]	-6	dCas9-VP64	positive selection	2435666
15757485	15757508	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGCGCCACCACGCCTAG	EPS8	ENSG00000151491	0.7395023947734947	[14,26]	[11,2]	3	dCas9-VP64	positive selection	2436125
15875203	15875226	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAGCTAATCTAGTGGGGACGTGG	EPS8	ENSG00000151491	-0.04510212151789125	[14,160]	[12,24]	0	dCas9-VP64	positive selection	2441236
15882209	15882232	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGACGCTCTAGGCACCGGGATGG	EPS8	ENSG00000151491	1.155788359887487	[72,6]	[7,30]	4	dCas9-VP64	positive selection	2441360
15882262	15882285	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCTAGTTCAGTGCTCGTGAGG	EPS8	ENSG00000151491	1.1426686741552463	[7,6]	[4,1]	4	dCas9-VP64	positive selection	2441361
15882233	15882256	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCTGGCCCACGCCGACTAAGG	EPS8	ENSG00000151491	2.346401059476001	[105,165]	[199,103]	7	dCas9-VP64	positive selection	2441362
15864967	15864990	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGTCTGG	EPS8	ENSG00000151491	-1.453588368366345	[188,63]	[8,9]	-8	dCas9-VP64	positive selection	2463554
15675553	15675576	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACGGCACTCCAGCCTGG	EPS8	ENSG00000151491	-0.056849389797668376	[44,102]	[10,20]	0	dCas9-VP64	positive selection	2473090
15739354	15739377	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAATGTTTTACCAGCTATCTAGG	EPS8	ENSG00000151491	-1.407043341160977	[503,368]	[33,36]	-7	dCas9-VP64	positive selection	2476439
15849467	15849490	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGCGTGAGCCACCGTGCCAGG	EPS8	ENSG00000151491	1.3051580023585738	[14,7]	[5,4]	5	dCas9-VP64	positive selection	2476735
15842724	15842747	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGACTGCTTGAGCCCAGG	EPS8	ENSG00000151491	0.4123872135065094	[127,354]	[119,88]	3	dCas9-VP64	positive selection	2478667
15856695	15856718	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCATGCTGGAATACAGTGG	EPS8	ENSG00000151491	1.306299962184366	[69,114]	[103,45]	7	dCas9-VP64	positive selection	2482939
15843454	15843477	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTGAGCCACCGTGCCAGG	EPS8	ENSG00000151491	-0.36417141382431395	[64,32]	[9,14]	-4	dCas9-VP64	positive selection	2483751
15751312	15751335	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACGCCACTGCACTCCAGCCTGG	EPS8	ENSG00000151491	-0.7543799798568478	[117,158]	[37,14]	-7	dCas9-VP64	positive selection	2484657
15851018	15851041	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTGGGAGGCTGAGGCAGGGGG	EPS8	ENSG00000151491	0.6350691816100226	[174,241]	[44,161]	5	dCas9-VP64	positive selection	2495379
15676215	15676238	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCTGGG	EPS8	ENSG00000151491	-0.30672599620467045	[261,149]	[50,57]	-3	dCas9-VP64	positive selection	2519892
15789648	15789671	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCGATCAAAGTCGGACCAAGG	EPS8	ENSG00000151491	0.45051620377704016	[164,159]	[54,88]	3	dCas9-VP64	positive selection	2530919
15789714	15789737	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACTAGCAGCCAGGAGGCGCAGG	EPS8	ENSG00000151491	2.0417000248664765	[38,17]	[67,11]	8	dCas9-VP64	positive selection	2530920
15789688	15789711	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTTCCAGAAGTGCCCTAACAGG	EPS8	ENSG00000151491	0.6703113688744118	[51,191]	[54,69]	5	dCas9-VP64	positive selection	2530921
15757485	15757508	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGCGCCACCACGCCTAG	EPS8	ENSG00000151491	0.19409034858978108	[82,214]	[36,71]	1	dCas9-VP64	positive selection	2531380
15875203	15875226	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAGCTAATCTAGTGGGGACGTGG	EPS8	ENSG00000151491	0.4598344795084126	[138,258]	[71,103]	3	dCas9-VP64	positive selection	2536491
15882209	15882232	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGACGCTCTAGGCACCGGGATGG	EPS8	ENSG00000151491	-0.5089027875677826	[92,41]	[12,16]	-5	dCas9-VP64	positive selection	2536615
15882262	15882285	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCTAGTTCAGTGCTCGTGAGG	EPS8	ENSG00000151491	-0.4687184825366784	[279,114]	[63,29]	-5	dCas9-VP64	positive selection	2536616
15882233	15882256	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCTGGCCCACGCCGACTAAGG	EPS8	ENSG00000151491	0.36646179052739436	[359,340]	[47,239]	3	dCas9-VP64	positive selection	2536617
15864967	15864990	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGTCTGG	EPS8	ENSG00000151491	0.10976477844408938	[73,10]	[24,4]	0	dCas9-VP64	positive selection	2558809
15675553	15675576	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACGGCACTCCAGCCTGG	EPS8	ENSG00000151491	-0.4857295796910447	[163,101]	[25,34]	-5	dCas9-VP64	positive selection	2568345
15739354	15739377	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAATGTTTTACCAGCTATCTAGG	EPS8	ENSG00000151491	-0.5925637368659709	[1038,268]	[178,108]	-6	dCas9-VP64	positive selection	2571694
15849467	15849490	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGCGTGAGCCACCGTGCCAGG	EPS8	ENSG00000151491	1.1554864993418033	[20,247]	[176,21]	7	dCas9-VP64	positive selection	2571990
15681212	15681235	12	+	27013184	SW480	treatment with recombinant TRAIL	ATAAACAAACCTACCATAAAGGG	EPS8	ENSG00000151491	1.0104350076196265	[338,193]	[247,221]	5	hSpCas9	positive selection	2962047
15681253	15681276	12	+	27013184	SW480	treatment with recombinant TRAIL	AACCATGTTCTCTGTCCGTCTGG	EPS8	ENSG00000151491	1.698334885682188	[176,206]	[311,202]	7	hSpCas9	positive selection	2962048
15681260	15681283	12	+	27013184	SW480	treatment with recombinant TRAIL	TTCTCTGTCCGTCTGGGAAAAGG	EPS8	ENSG00000151491	-0.6243248889386235	[314,528]	[34,229]	-3	hSpCas9	positive selection	2962049
15681264	15681287	12	+	27013184	SW480	treatment with recombinant TRAIL	CTGTCCGTCTGGGAAAAGGTAGG	EPS8	ENSG00000151491	0.31835303038262247	[224,354]	[76,260]	1	hSpCas9	positive selection	2962050
15682884	15682907	12	+	27013184	SW480	treatment with recombinant TRAIL	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.7774856529223506	[159,267]	[17,101]	-4	hSpCas9	positive selection	2962051
15682885	15682908	12	+	27013184	SW480	treatment with recombinant TRAIL	CAACTTACTTCATCTGAGATGGG	EPS8	ENSG00000151491	1.0731408105712352	[470,926]	[496,785]	5	hSpCas9	positive selection	2962052
15682904	15682927	12	+	27013184	SW480	treatment with recombinant TRAIL	TGGGTACATTCCAAAACTACTGG	EPS8	ENSG00000151491	-1.0038476302743455	[138,130]	[24,34]	-4	hSpCas9	positive selection	2962053
15682905	15682928	12	+	27013184	SW480	treatment with recombinant TRAIL	GGGTACATTCCAAAACTACTGGG	EPS8	ENSG00000151491	-0.20093698886578992	[63,200]	[77,3]	-1	hSpCas9	positive selection	2962054
15662025	15662048	12	-	27013184	SW480	treatment with recombinant TRAIL	AGCCCGCATTGACAGAGATGTGG	EPS8	ENSG00000151491	-0.6918539603020228	[509,886]	[99,298]	-3	hSpCas9	positive selection	2962055
15662049	15662072	12	-	27013184	SW480	treatment with recombinant TRAIL	GGAAGAAACACCTGAGATGATGG	EPS8	ENSG00000151491	0.01964421155095808	[28,51]	[1,38]	0	hSpCas9	positive selection	2962056
15662070	15662093	12	-	27013184	SW480	treatment with recombinant TRAIL	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	2.5647722191888462	[65,68]	[145,208]	9	hSpCas9	positive selection	2962057
15670900	15670923	12	-	27013184	SW480	treatment with recombinant TRAIL	ACAAAGGAAGAATTATGCACGGG	EPS8	ENSG00000151491	-3.729105349236563	[251,306]	[1,18]	-9	hSpCas9	positive selection	2962059
15670901	15670924	12	-	27013184	SW480	treatment with recombinant TRAIL	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	1.5764272782697377	[11,43]	[20,52]	7	hSpCas9	positive selection	2962060
15681221	15681244	12	-	27013184	SW480	treatment with recombinant TRAIL	GTGCAAAGGCCCTTTATGGTAGG	EPS8	ENSG00000151491	0.5814218993018054	[64,133]	[72,46]	3	hSpCas9	positive selection	2962061
15681225	15681248	12	-	27013184	SW480	treatment with recombinant TRAIL	ACAAGTGCAAAGGCCCTTTATGG	EPS8	ENSG00000151491	0.8651525586957032	[2,1]	[1,1]	4	hSpCas9	positive selection	2962062
15681235	15681258	12	-	27013184	SW480	treatment with recombinant TRAIL	TGGTTCAAAAACAAGTGCAAAGG	EPS8	ENSG00000151491	0.9664565506760621	[80,31]	[72,15]	4	hSpCas9	positive selection	2962063
15681268	15681291	12	-	27013184	SW480	treatment with recombinant TRAIL	ATCACCTACCTTTTCCCAGACGG	EPS8	ENSG00000151491	-3.651838275092112	[243,363]	[1,21]	-9	hSpCas9	positive selection	2962064
15681294	15681317	12	-	27013184	SW480	treatment with recombinant TRAIL	TATTATTATTACAGTGGCTACGG	EPS8	ENSG00000151491	-2.87924579297702	[29,38]	[1,1]	-8	hSpCas9	positive selection	2962065
15682944	15682967	12	-	27013184	SW480	treatment with recombinant TRAIL	CAAGTGAAAGACACAATGAATGG	EPS8	ENSG00000151491	-2.7112941663524075	[106,34]	[1,8]	-8	hSpCas9	positive selection	2962066
15662022	15662045	12	+	27013184	SW480	treatment with recombinant TRAIL	TTACCACATCTCTGTCAATGCGG	EPS8	ENSG00000151491	3.0544505857555087	[103,184]	[701,224]	9	hSpCas9	positive selection	2962068
15662023	15662046	12	+	27013184	SW480	treatment with recombinant TRAIL	TACCACATCTCTGTCAATGCGGG	EPS8	ENSG00000151491	-0.38180050561010404	[537,406]	[105,232]	-2	hSpCas9	positive selection	2962069
15662039	15662062	12	+	27013184	SW480	treatment with recombinant TRAIL	ATGCGGGCTGCCATCATCTCAGG	EPS8	ENSG00000151491	-0.31725660902345676	[204,510]	[148,76]	-1	hSpCas9	positive selection	2962070
15662069	15662092	12	+	27013184	SW480	treatment with recombinant TRAIL	TCCTGCTCATGATACTGCCTTGG	EPS8	ENSG00000151491	0.25579657142092205	[778,828]	[337,519]	1	hSpCas9	positive selection	2962071
15666423	15666446	12	+	27013184	SW480	treatment with recombinant TRAIL	TCTTTCAATGCTTTTACCTCAGG	EPS8	ENSG00000151491	-0.40049537502448795	[514,704]	[213,171]	-2	hSpCas9	positive selection	2962072
15666424	15666447	12	+	27013184	SW480	treatment with recombinant TRAIL	CTTTCAATGCTTTTACCTCAGGG	EPS8	ENSG00000151491	3.1370678105318346	[488,595]	[1473,2848]	9	hSpCas9	positive selection	2962073
15670843	15670866	12	+	27013184	SW480	treatment with recombinant TRAIL	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	0.2217733717492245	[5,18]	[5,5]	1	hSpCas9	positive selection	2962074
15654186	15654209	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	0.4668191748001539	[4,5]	[5,6]	8	hSpCas9	positive selection	2986155
15670844	15670867	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	-0.04345173587752556	[3,3]	[2,3]	0	hSpCas9	positive selection	2986156
15666470	15666493	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.8325868176898628	[2,2]	[1,0]	-8	hSpCas9	positive selection	2986157
15665792	15665815	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.3783844830336451	[4,4]	[4,6]	7	hSpCas9	positive selection	2986158
15654186	15654209	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	0.5603203565716723	[4,4]	[5,5]	8	hSpCas9	positive selection	3054013
15670844	15670867	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	0.045117311632557264	[3,3]	[4,1]	0	hSpCas9	positive selection	3054014
15666470	15666493	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.0037326977911830705	[2,2]	[2,0]	0	hSpCas9	positive selection	3054015
15665792	15665815	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.058185161122521256	[4,4]	[4,2]	1	hSpCas9	positive selection	3054016
15670901	15670924		-	24336571	A375	resistance to PLX after 7 days	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	-0.20108832255773323	[5,5]	[5,4]	-6	hSpCas9	positive selection	3112328
15682884	15682907		+	24336571	A375	resistance to PLX after 7 days	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.43407985153590034	[5,4]	[4,2]	-9	hSpCas9	positive selection	3112330
15682914	15682937		-	24336571	A375	resistance to PLX after 7 days	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	-0.2045500986808626	[24,28]	[22,22]	-6	hSpCas9	positive selection	3112331
15670901	15670924		-	24336571	A375	resistance to PLX after 14 days	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	-0.06664229319104376	[5,4]	[2,1]	0	hSpCas9	positive selection	3170121
15682884	15682907		+	24336571	A375	resistance to PLX after 14 days	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.5151788585817811	[6,4]	[1,1]	-6	hSpCas9	positive selection	3170123
15682914	15682937		-	24336571	A375	resistance to PLX after 14 days	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	-1.1112372620854953	[20,20]	[3,3]	-9	hSpCas9	positive selection	3170124
15670901	15670924		-	24336571	A375	viability after 7 days	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.39037766387529815	[4]	[5,5]	6	hSpCas9	negative selection	3227914
15682884	15682907		+	24336571	A375	viability after 7 days	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-1.1878117756293314	[13]	[5,4]	-9	hSpCas9	negative selection	3227916
15682914	15682937		-	24336571	A375	viability after 7 days	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.7797580329464184	[15]	[24,28]	9	hSpCas9	negative selection	3227917
15670901	15670924		-	24336571	A375	viability after 14 days	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.1951340079479118	[4]	[5,4]	2	hSpCas9	negative selection	3285707
15682884	15682907		+	24336571	A375	viability after 14 days	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-1.0433421207282745	[13]	[6,4]	-8	hSpCas9	negative selection	3285709
15682914	15682937		-	24336571	A375	viability after 14 days	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.44106532722795444	[15]	[20,20]	5	hSpCas9	negative selection	3285710
15669786	15669809	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.45095000092722326	[343,282]	[0,1]	-3	hSpCas9	positive selection	3348207
15669804	15669827	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	-1.0488695387585993	[320,311]	[0,0]	-7	hSpCas9	positive selection	3348208
15682884	15682907	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.7196890701770995	[77,107]	[0,0]	3	hSpCas9	positive selection	3348209
15670901	15670924	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.08740121000352279	[143,143]	[0,0]	0	hSpCas9	positive selection	3367417
15682914	15682937	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	-1.3087278267252564	[378,378]	[0,0]	-8	hSpCas9	positive selection	3367418
15669721	15669744	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3367419
15654186	15654209	12	-	26780180	HT29	viability (Avana library 4 designs)	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	-0.0818131607032475	[]	[]	-1	hSpCas9	negative selection	3422978
15670843	15670866	12	+	26780180	HT29	viability (Avana library 4 designs)	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	1.97127569990241	[]	[]	7	hSpCas9	negative selection	3422979
15666470	15666493	12	-	26780180	HT29	viability (Avana library 4 designs)	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.18324112272606	[]	[]	-3	hSpCas9	negative selection	3422980
15665792	15665815	12	-	26780180	HT29	viability (Avana library 4 designs)	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.0484597244667178	[]	[]	0	hSpCas9	negative selection	3422981
15665792	15665815	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.0193053205501876	[]	[]	0	hSpCas9	negative selection	3503905
15654186	15654209	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	0.322744995024763	[]	[]	0	hSpCas9	negative selection	3503906
15666470	15666493	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.81179980780985	[]	[]	2	hSpCas9	negative selection	3503907
15670843	15670866	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	-5.03263225414508	[]	[]	-5	hSpCas9	negative selection	3503908
15665802	15665825	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTAACATCCACCTGGGTGACGG	EPS8	ENSG00000151491	0.70130151289818	[]	[]	1	hSpCas9	negative selection	3503909
15669383	15669406	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-11.0154884407937	[]	[]	-8	hSpCas9	negative selection	3503910
15665792	15665815	12	-	26780180	A375	viability (Avana lentiGuide)	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	-0.5870499658525	[]	[]	-1	hSpCas9	negative selection	3612564
15654186	15654209	12	-	26780180	A375	viability (Avana lentiGuide)	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	-1.16754414316336	[]	[]	-2	hSpCas9	negative selection	3612565
15666470	15666493	12	-	26780180	A375	viability (Avana lentiGuide)	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.684893574846604	[]	[]	0	hSpCas9	negative selection	3612566
15670843	15670866	12	+	26780180	A375	viability (Avana lentiGuide)	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	-5.45286714013403	[]	[]	-8	hSpCas9	negative selection	3612567
15665802	15665825	12	+	26780180	A375	viability (Avana lentiGuide)	TCTAACATCCACCTGGGTGACGG	EPS8	ENSG00000151491	-2.01103278958569	[]	[]	-3	hSpCas9	negative selection	3612568
15669383	15669406	12	+	26780180	A375	viability (Avana lentiGuide)	TTACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	3.56248436549742	[]	[]	3	hSpCas9	negative selection	3612569
15665792	15665815	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.034977228232887125	[5]	[5,5]	0	hSpCas9	positive selection	3721223
15654186	15654209	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	-0.026597135311991205	[7]	[7,6]	0	hSpCas9	positive selection	3721224
15666470	15666493	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.4498737635726897	[4]	[4,1]	-6	hSpCas9	positive selection	3721225
15670843	15670866	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	-0.4450734395483713	[5]	[3,3]	-6	hSpCas9	positive selection	3721226
15665802	15665825	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTAACATCCACCTGGGTGACGG	EPS8	ENSG00000151491	0.31336193171252424	[5]	[5,6]	8	hSpCas9	positive selection	3721227
15669383	15669406	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.7232550268090164	[5]	[2,2]	-8	hSpCas9	positive selection	3721228
15665792	15665815	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGATGTTAGAAGTCGAGTGG	EPS8	ENSG00000151491	0.062403100402953465	[6]	[4,6]	1	hSpCas9	positive selection	3829830
15654186	15654209	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACTGTCAATGGTGATGAACGG	EPS8	ENSG00000151491	-0.08774606970655963	[6]	[5,4]	-1	hSpCas9	positive selection	3829831
15666470	15666493	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.00409452741650454	[4]	[5,2]	0	hSpCas9	positive selection	3829832
15670843	15670866	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAAGCATCTTACTTCAACACGG	EPS8	ENSG00000151491	0.07590059087477141	[4]	[5,3]	1	hSpCas9	positive selection	3829833
15665802	15665825	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTAACATCCACCTGGGTGACGG	EPS8	ENSG00000151491	-0.21129669056513234	[5]	[2,5]	-3	hSpCas9	positive selection	3829834
15669383	15669406	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	0.24738147703616908	[6]	[6,6]	6	hSpCas9	positive selection	3829835
15670901	15670924	12	-	26780180	A375	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	1.19317599561855	[]	[]	6	hSpCas9	negative selection	3937185
15669804	15669827	12	-	26780180	A375	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	1.77199118584826	[]	[]	9	hSpCas9	negative selection	3937186
15682884	15682907	12	+	26780180	A375	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.725545588092553	[]	[]	2	hSpCas9	negative selection	3937187
15669786	15669809	12	+	26780180	A375	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	1.81261954006355	[]	[]	9	hSpCas9	negative selection	3937188
15682914	15682937	12	-	26780180	A375	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.459636546328232	[]	[]	1	hSpCas9	negative selection	3937189
15669721	15669744	12	+	26780180	A375	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	1.4498676244265	[]	[]	8	hSpCas9	negative selection	3937190
15670901	15670924	12	-	26780180	HT29	viability (GeCKOv2 library)	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	1.23127010211568	[]	[]	6	hSpCas9	negative selection	4045151
15669804	15669827	12	-	26780180	HT29	viability (GeCKOv2 library)	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.609528245057118	[]	[]	2	hSpCas9	negative selection	4045152
15682884	15682907	12	+	26780180	HT29	viability (GeCKOv2 library)	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.739202052158187	[]	[]	3	hSpCas9	negative selection	4045153
15669786	15669809	12	+	26780180	HT29	viability (GeCKOv2 library)	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	1.38449687227965	[]	[]	7	hSpCas9	negative selection	4045154
15682914	15682937	12	-	26780180	HT29	viability (GeCKOv2 library)	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.412490651375673	[]	[]	1	hSpCas9	negative selection	4045155
15669721	15669744	12	+	26780180	HT29	viability (GeCKOv2 library)	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	1.35780538356461	[]	[]	7	hSpCas9	negative selection	4045156
15670901	15670924	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	-0.36332818584755733	[2]	[1,0]	-7	hSpCas9	positive selection	4135050
15682884	15682907	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.5769429121290831	[2]	[1,0]	-9	hSpCas9	positive selection	4135052
15682914	15682937	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.0054152724762254745	[3]	[3,1]	0	hSpCas9	positive selection	4135053
15670901	15670924	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	1.2471867484216617	[2]	[0,2,1,3]	9	hSpCas9	positive selection	4199072
15682884	15682907	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.027830689345203996	[3]	[0,2,1,0]	0	hSpCas9	positive selection	4199074
15682914	15682937	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	-0.18408936127137987	[3]	[2,0,2,0]	-3	hSpCas9	positive selection	4199075
15669786	15669809	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.2246217704426941	[4]	[3,3]	4	hSpCas9	positive selection	4269063
15669804	15669827	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.058703625622500144	[4]	[3,2]	1	hSpCas9	positive selection	4269064
15682884	15682907	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.60476748476543	[2]	[3,3]	9	hSpCas9	positive selection	4269065
15670901	15670924	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	-0.24823567023509174	[2]	[2,0]	-5	hSpCas9	positive selection	4333328
15682914	15682937	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.11058446598374322	[3]	[3,2]	2	hSpCas9	positive selection	4333329
15669721	15669744	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.1960950325841433	[2]	[1,0]	-4	hSpCas9	positive selection	4333330
15658565	15658587	12	-	27760321	OCIAML3	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	0.20196238986304302	[414,355]	[274,437]	2	hSpCas9	negative selection	4398113
15665797	15665819	12	+	27760321	OCIAML3	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.8176125626679454	[666,610]	[804,978]	8	hSpCas9	negative selection	4398114
15669384	15669406	12	+	27760321	OCIAML3	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	0.9403074425637257	[181,149]	[204,303]	9	hSpCas9	negative selection	4398115
15669787	15669809	12	+	27760321	OCIAML3	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.7541250169219431	[975,821]	[913,1529]	8	hSpCas9	negative selection	4398116
15654230	15654252	12	-	27760321	OCIAML3	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	0.4304378267123026	[50,31]	[26,63]	5	hSpCas9	negative selection	4398117
15658565	15658587	12	-	27760321	OCIAML2	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	0.18454687397793895	[414,355]	[260,474]	2	hSpCas9	negative selection	4481576
15665797	15665819	12	+	27760321	OCIAML2	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.49289014797765396	[666,610]	[756,687]	6	hSpCas9	negative selection	4481577
15669384	15669406	12	+	27760321	OCIAML2	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.6185172983942759	[181,149]	[77,98]	-6	hSpCas9	negative selection	4481578
15669787	15669809	12	+	27760321	OCIAML2	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.24759204344331698	[975,821]	[791,949]	3	hSpCas9	negative selection	4481579
15654230	15654252	12	-	27760321	OCIAML2	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	1.4086383421349544	[50,31]	[82,93]	9	hSpCas9	negative selection	4481580
15658565	15658587	12	-	27760321	MV411	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-1.6908445910320415	[414,355]	[30,149]	-8	hSpCas9	negative selection	4565039
15665797	15665819	12	+	27760321	MV411	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.9611454777490256	[666,610]	[924,663]	7	hSpCas9	negative selection	4565040
15669384	15669406	12	+	27760321	MV411	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	0.21939426259702932	[181,149]	[60,225]	1	hSpCas9	negative selection	4565041
15669787	15669809	12	+	27760321	MV411	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.6891162254344851	[975,821]	[1087,749]	5	hSpCas9	negative selection	4565042
15654230	15654252	12	-	27760321	MV411	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	-0.25380089033835684	[50,31]	[36,0]	-2	hSpCas9	negative selection	4565043
15658565	15658587	12	-	27760321	HL60	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.753440038044959	[414,355]	[160,212]	-7	hSpCas9	negative selection	4648502
15665797	15665819	12	+	27760321	HL60	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.004154905224029615	[666,610]	[500,546]	0	hSpCas9	negative selection	4648503
15669384	15669406	12	+	27760321	HL60	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.24709466521225987	[181,149]	[54,175]	-3	hSpCas9	negative selection	4648504
15669787	15669809	12	+	27760321	HL60	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.018132047335496893	[975,821]	[686,797]	0	hSpCas9	negative selection	4648505
15654230	15654252	12	-	27760321	HL60	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	-0.39406994687273933	[50,31]	[21,28]	-4	hSpCas9	negative selection	4648506
15658565	15658587	12	-	27760321	HT1080	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.966658258751131	[355,277]	[24,107]	-4	hSpCas9	negative selection	4731965
15665797	15665819	12	+	27760321	HT1080	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	-1.80199295416852	[610,476]	[117,0]	-6	hSpCas9	negative selection	4731966
15669384	15669406	12	+	27760321	HT1080	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	3.420562900897913	[149,116]	[546,593]	9	hSpCas9	negative selection	4731967
15669787	15669809	12	+	27760321	HT1080	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-8.187946646763354	[821,641]	[0,0]	-9	hSpCas9	negative selection	4731968
15654230	15654252	12	-	27760321	HT1080	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	4.232328842956574	[31,24]	[63,376]	9	hSpCas9	negative selection	4731969
15658565	15658587	12	-	27760321	HT29	viability after 7 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.40505689417134016	[355,277]	[111,345,432]	-5	hSpCas9	negative selection	4815428
15665797	15665819	12	+	27760321	HT29	viability after 7 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.29912337115300225	[610,476]	[725,868,962]	4	hSpCas9	negative selection	4815429
15669384	15669406	12	+	27760321	HT29	viability after 7 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	0.04152937869849649	[149,116]	[61,231,217]	0	hSpCas9	negative selection	4815430
15669787	15669809	12	+	27760321	HT29	viability after 7 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.13510966357697363	[821,641]	[1176,787,656]	-2	hSpCas9	negative selection	4815431
15654230	15654252	12	-	27760321	HT29	viability after 7 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	1.2491860363993177	[31,24]	[77,97,83]	9	hSpCas9	negative selection	4815432
15658565	15658587	12	-	27760321	HT29	viability after 25 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-1.2279657273255453	[355,277]	[172,122,167]	-7	hSpCas9	negative selection	4898891
15665797	15665819	12	+	27760321	HT29	viability after 25 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	-0.23260718848160633	[610,476]	[549,318,737]	-2	hSpCas9	negative selection	4898892
15669384	15669406	12	+	27760321	HT29	viability after 25 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.5903852420927107	[149,116]	[19,100,197]	-5	hSpCas9	negative selection	4898893
15669787	15669809	12	+	27760321	HT29	viability after 25 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.15333144303293955	[821,641]	[846,732,659]	-1	hSpCas9	negative selection	4898894
15654230	15654252	12	-	27760321	HT29	viability after 25 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	0.6067645871129792	[31,24]	[4,92,53]	6	hSpCas9	negative selection	4898895
15658565	15658587	12	-	27760321	HT29	viability after 22 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.9711279186735386	[355,277]	[294,65,196]	-6	hSpCas9	negative selection	4982354
15665797	15665819	12	+	27760321	HT29	viability after 22 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	-0.3799771168633381	[610,476]	[277,627,549]	-4	hSpCas9	negative selection	4982355
15669384	15669406	12	+	27760321	HT29	viability after 22 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	0.2182159508416559	[149,116]	[217,195,122]	2	hSpCas9	negative selection	4982356
15669787	15669809	12	+	27760321	HT29	viability after 22 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.010748102447999619	[821,641]	[920,623,973]	0	hSpCas9	negative selection	4982357
15654230	15654252	12	-	27760321	HT29	viability after 22 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	1.1860570666142367	[31,24]	[6,117,101]	9	hSpCas9	negative selection	4982358
15658565	15658587	12	-	27760321	HT29	viability after 19 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.9431629555087873	[355,277]	[452,105,39]	-6	hSpCas9	negative selection	5065817
15665797	15665819	12	+	27760321	HT29	viability after 19 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.012552166597445291	[610,476]	[660,760,469]	0	hSpCas9	negative selection	5065818
15669384	15669406	12	+	27760321	HT29	viability after 19 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.12403886197904845	[149,116]	[162,183,77]	-1	hSpCas9	negative selection	5065819
15669787	15669809	12	+	27760321	HT29	viability after 19 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.11944576200668466	[821,641]	[1102,624,623]	-1	hSpCas9	negative selection	5065820
15654230	15654252	12	-	27760321	HT29	viability after 19 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	-0.16907856844677216	[31,24]	[57,29,2]	-1	hSpCas9	negative selection	5065821
15658565	15658587	12	-	27760321	HT29	viability after 16 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.32880300118529826	[355,277]	[98,312,416]	-4	hSpCas9	negative selection	5149280
15665797	15665819	12	+	27760321	HT29	viability after 16 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.15235361477737708	[610,476]	[625,615,783]	1	hSpCas9	negative selection	5149281
15669384	15669406	12	+	27760321	HT29	viability after 16 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-1.4133997565645555	[149,116]	[93,47,29]	-8	hSpCas9	negative selection	5149282
15669787	15669809	12	+	27760321	HT29	viability after 16 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.2241348295597856	[821,641]	[1037,745,1098]	2	hSpCas9	negative selection	5149283
15654230	15654252	12	-	27760321	HT29	viability after 16 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	0.18262542359714873	[31,24]	[33,49,23]	2	hSpCas9	negative selection	5149284
15658565	15658587	12	-	27760321	HT29	viability after 13 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.5589292011675958	[355,277]	[111,332,300]	-6	hSpCas9	negative selection	5232743
15665797	15665819	12	+	27760321	HT29	viability after 13 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.23744870541937935	[610,476]	[651,867,713]	3	hSpCas9	negative selection	5232744
15669384	15669406	12	+	27760321	HT29	viability after 13 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.7578920174264212	[149,116]	[47,103,120]	-7	hSpCas9	negative selection	5232745
15669787	15669809	12	+	27760321	HT29	viability after 13 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.2882125007280758	[821,641]	[1347,841,926]	3	hSpCas9	negative selection	5232746
15654230	15654252	12	-	27760321	HT29	viability after 13 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	-0.09694370379436323	[31,24]	[0,29,59]	-1	hSpCas9	negative selection	5232747
15658565	15658587	12	-	27760321	HT29	viability after 10 days	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.5254278294038782	[355,277]	[175,340,308]	-6	hSpCas9	negative selection	5316206
15665797	15665819	12	+	27760321	HT29	viability after 10 days	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.3389496314167457	[610,476]	[931,461,1164]	4	hSpCas9	negative selection	5316207
15669384	15669406	12	+	27760321	HT29	viability after 10 days	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.059165418427216565	[149,116]	[210,158,110]	-1	hSpCas9	negative selection	5316208
15669787	15669809	12	+	27760321	HT29	viability after 10 days	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.23994439961517378	[821,641]	[1292,784,1149]	3	hSpCas9	negative selection	5316209
15654230	15654252	12	-	27760321	HT29	viability after 10 days	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	1.0187993040519356	[31,24]	[9,193,16]	9	hSpCas9	negative selection	5316210
15658565	15658587	12	-	27760321	MOLM13	viability	GAGGGTGTTTTAACGCTGCGGG	EPS8	ENSG00000151491	-0.9050891473897246	[414,355]	[131,101]	-5	hSpCas9	negative selection	5399669
15665797	15665819	12	+	27760321	MOLM13	viability	CGACTTCTAACATCCACCTGGG	EPS8	ENSG00000151491	0.2687533613740176	[666,610]	[612,281]	1	hSpCas9	negative selection	5399670
15669384	15669406	12	+	27760321	MOLM13	viability	TACCTTAACCTCATCACACTGG	EPS8	ENSG00000151491	-0.3187457732094643	[181,149]	[131,25]	-2	hSpCas9	negative selection	5399671
15669787	15669809	12	+	27760321	MOLM13	viability	CATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.27787550601671307	[975,821]	[603,619]	2	hSpCas9	negative selection	5399672
15654230	15654252	12	-	27760321	MOLM13	viability	CTTAGTCCCCTATTGAATAAGG	EPS8	ENSG00000151491	1.8881786833878447	[50,31]	[127,48]	9	hSpCas9	negative selection	5399673
15789200	15789223	12	+	27661255	K562	viability	GCCGCGAGCCCAGACGAGGTGGG	EPS8	ENSG00000151491	0.44864057075271746	[216,293]	[296,259]	9	dCas9-KRAB	negative selection	5477637
15788992	15789015	12	-	27661255	K562	viability	GTTGGCAGCCAGGTGCGGTAGGG	EPS8	ENSG00000151491	0.07789924188425865	[854,809]	[829,593]	2	dCas9-KRAB	negative selection	5477638
15669786	15669809	12	+	27260156	BXPC3	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.008554009173290522	[1108]	[1022,1115,1315,1231]	0	hSpCas9	negative selection	5541523
15669804	15669827	12	-	27260156	BXPC3	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.2737237064383886	[987]	[1229,1150,1213,1419]	6	hSpCas9	negative selection	5541524
15682884	15682907	12	+	27260156	BXPC3	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.07816635505937691	[415]	[437,377,336,500]	-2	hSpCas9	negative selection	5541525
15670901	15670924	12	-	27260156	BXPC3	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.14789962783735117	[328]	[312,356,427,440]	3	hSpCas9	negative selection	5605788
15682914	15682937	12	-	27260156	BXPC3	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.21703041449018734	[707]	[715,772,989,996]	5	hSpCas9	negative selection	5605789
15669721	15669744	12	+	27260156	BXPC3	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.02071760556846103	[269]	[246,266,282,323]	0	hSpCas9	negative selection	5605790
15669786	15669809	12	+	27260156	A673	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.15600625943908075	[1108]	[1643,1385,1310,1620]	4	hSpCas9	negative selection	5662774
15669804	15669827	12	-	27260156	A673	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.26310476546614536	[987]	[1506,1444,1350,1396]	6	hSpCas9	negative selection	5662775
15682884	15682907	12	+	27260156	A673	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.08729719972661759	[415]	[547,410,451,479]	-2	hSpCas9	negative selection	5662776
15670901	15670924	12	-	27260156	A673	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.182176714456444	[328]	[521,445,429,399]	4	hSpCas9	negative selection	5727039
15682914	15682937	12	-	27260156	A673	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.06425206554797291	[707]	[831,968,901,838]	1	hSpCas9	negative selection	5727040
15669721	15669744	12	+	27260156	A673	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.1927169966732002	[269]	[346,413,429,280]	4	hSpCas9	negative selection	5727041
15669786	15669809	12	+	27260156	A375	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.22871059655598058	[1108]	[1541,1519,1496,1507]	3	hSpCas9	negative selection	5784025
15669804	15669827	12	-	27260156	A375	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.32376766708315907	[987]	[1208,1767,1246,1574]	5	hSpCas9	negative selection	5784026
15682884	15682907	12	+	27260156	A375	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.01900084386119419	[415]	[447,763,412,391]	0	hSpCas9	negative selection	5784027
15670901	15670924	12	-	27260156	A375	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.26014715207291284	[328]	[406,701,420,354]	4	hSpCas9	negative selection	5848290
15682914	15682937	12	-	27260156	A375	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.5115246797538608	[707]	[807,1434,1019,1447]	7	hSpCas9	negative selection	5848291
15669721	15669744	12	+	27260156	A375	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.35171735247315916	[269]	[517,397,332,363]	5	hSpCas9	negative selection	5848292
15669786	15669809	12	+	27260156	COLO741	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.012114610938201542	[1108]	[1613,1286,1333]	0	hSpCas9	negative selection	5905276
15669804	15669827	12	-	27260156	COLO741	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.420172764122521	[987]	[2042,1611,1455]	8	hSpCas9	negative selection	5905277
15682884	15682907	12	+	27260156	COLO741	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.1518200229408466	[415]	[709,561,513]	3	hSpCas9	negative selection	5905278
15670901	15670924	12	-	27260156	COLO741	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.43121371196653424	[328]	[743,558,421]	8	hSpCas9	negative selection	5969541
15682914	15682937	12	-	27260156	COLO741	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.38080409291277306	[707]	[1147,1334,1054]	7	hSpCas9	negative selection	5969542
15669721	15669744	12	+	27260156	COLO741	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.3790490150328603	[269]	[618,346,396]	7	hSpCas9	negative selection	5969543
15669786	15669809	12	+	27260156	CAL120	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.0037332120714941297	[1108]	[1526,998,1620]	0	hSpCas9	negative selection	6026527
15669804	15669827	12	-	27260156	CAL120	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.15899241188474167	[987]	[2110,1046,1075]	2	hSpCas9	negative selection	6026528
15682884	15682907	12	+	27260156	CAL120	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.1563568739068419	[415]	[475,620,300]	-2	hSpCas9	negative selection	6026529
15670901	15670924	12	-	27260156	CAL120	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.44338621210785994	[328]	[714,438,539]	6	hSpCas9	negative selection	6090792
15682914	15682937	12	-	27260156	CAL120	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.36203481057706255	[707]	[1117,1179,1096]	5	hSpCas9	negative selection	6090793
15669721	15669744	12	+	27260156	CAL120	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.25939839179683943	[269]	[239,323,271]	-4	hSpCas9	negative selection	6090794
15669786	15669809	12	+	27260156	CADOES1	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.05412317563365798	[1108]	[1062,1025,1081,1113]	0	hSpCas9	negative selection	6147778
15669804	15669827	12	-	27260156	CADOES1	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.5082238654648441	[987]	[1521,1454,1086,1157]	8	hSpCas9	negative selection	6147779
15682884	15682907	12	+	27260156	CADOES1	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.15257794377402553	[415]	[466,429,422,398]	2	hSpCas9	negative selection	6147780
15670901	15670924	12	-	27260156	CADOES1	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.4632926417380645	[328]	[432,357,455,440]	7	hSpCas9	negative selection	6212043
15682914	15682937	12	-	27260156	CADOES1	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.5217592957982804	[707]	[798,844,953,1192]	8	hSpCas9	negative selection	6212044
15669721	15669744	12	+	27260156	CADOES1	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.28418776986260474	[269]	[412,317,260,227]	5	hSpCas9	negative selection	6212045
15669786	15669809	12	+	27260156	EWS502	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.3126131492071085	[1108]	[1490,1181,1668,1500]	5	hSpCas9	negative selection	6269029
15669804	15669827	12	-	27260156	EWS502	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.31132586527997197	[987]	[963,1305,1430,1547]	5	hSpCas9	negative selection	6269030
15682884	15682907	12	+	27260156	EWS502	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.4495527003057724	[415]	[640,607,527,622]	7	hSpCas9	negative selection	6269031
15670901	15670924	12	-	27260156	EWS502	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.1102110788565655	[328]	[319,335,367,495]	2	hSpCas9	negative selection	6333294
15682914	15682937	12	-	27260156	EWS502	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.4376792903303346	[707]	[895,1053,994,1134]	7	hSpCas9	negative selection	6333295
15669721	15669744	12	+	27260156	EWS502	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.5589184820122733	[269]	[378,536,359,405]	8	hSpCas9	negative selection	6333296
15669786	15669809	12	+	27260156	EW8	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.13067727786653816	[1108]	[926,851,1064,1067]	2	hSpCas9	negative selection	6390280
15669804	15669827	12	-	27260156	EW8	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.32797245449696133	[987]	[1146,958,974,956]	6	hSpCas9	negative selection	6390281
15682884	15682907	12	+	27260156	EW8	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.43243951416046233	[415]	[672,371,415,387]	7	hSpCas9	negative selection	6390282
15670901	15670924	12	-	27260156	EW8	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.04350426568617455	[328]	[270,288,220,325]	0	hSpCas9	negative selection	6454545
15682914	15682937	12	-	27260156	EW8	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.4336474393689771	[707]	[947,1060,602,535]	7	hSpCas9	negative selection	6454546
15669721	15669744	12	+	27260156	EW8	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.08646355211720391	[269]	[172,298,240,207]	1	hSpCas9	negative selection	6454547
15669786	15669809	12	+	27260156	CORL105	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.1407722968758205	[1108]	[1302,1489,1855,1137]	2	hSpCas9	negative selection	6511531
15669804	15669827	12	-	27260156	CORL105	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.27330808511733773	[987]	[1356,1375,1717,1189]	5	hSpCas9	negative selection	6511532
15682884	15682907	12	+	27260156	CORL105	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.04078883435057812	[415]	[412,712,438,316]	0	hSpCas9	negative selection	6511533
15670901	15670924	12	-	27260156	CORL105	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.26326722424903476	[328]	[600,379,402,461]	5	hSpCas9	negative selection	6575796
15682914	15682937	12	-	27260156	CORL105	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.2719908596308931	[707]	[1055,1055,1074,828]	5	hSpCas9	negative selection	6575797
15669721	15669744	12	+	27260156	CORL105	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.16421239900253792	[269]	[208,270,340,313]	-3	hSpCas9	negative selection	6575798
15669786	15669809	12	+	27260156	HS294T	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.32120000361033796	[1108]	[535,712,399,475]	4	hSpCas9	negative selection	6632782
15669804	15669827	12	-	27260156	HS294T	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.5050156768661314	[987]	[587,590,456,520]	6	hSpCas9	negative selection	6632783
15682884	15682907	12	+	27260156	HS294T	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.24471391889221972	[415]	[110,132,248,295]	3	hSpCas9	negative selection	6632784
15670901	15670924	12	-	27260156	HS294T	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.41574091292465365	[328]	[80,166,138,325]	5	hSpCas9	negative selection	6697047
15682914	15682937	12	-	27260156	HS294T	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.3646252860409068	[707]	[267,453,315,379]	5	hSpCas9	negative selection	6697048
15669721	15669744	12	+	27260156	HS294T	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.1320889324307819	[269]	[93,108,88,86]	-2	hSpCas9	negative selection	6697049
15669786	15669809	12	+	27260156	HCC44	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.16325387087255416	[1108]	[1387,1406,1656,1202]	2	hSpCas9	negative selection	6754033
15669804	15669827	12	-	27260156	HCC44	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.15739849841621245	[987]	[1530,673,1567,1360]	2	hSpCas9	negative selection	6754034
15682884	15682907	12	+	27260156	HCC44	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.25041831672900466	[415]	[533,260,345,458]	-4	hSpCas9	negative selection	6754035
15670901	15670924	12	-	27260156	HCC44	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.04241647811264082	[328]	[370,349,574,273]	0	hSpCas9	negative selection	6818298
15682914	15682937	12	-	27260156	HCC44	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.5135709921162388	[707]	[1095,1210,1210,1045]	8	hSpCas9	negative selection	6818299
15669721	15669744	12	+	27260156	HCC44	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.17492662244740953	[269]	[247,374,209,220]	-3	hSpCas9	negative selection	6818300
15669786	15669809	12	+	27260156	G402	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.48979320489227973	[1108]	[2613,2407,1500,1235]	6	hSpCas9	negative selection	6875284
15669804	15669827	12	-	27260156	G402	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.4608236169191289	[987]	[2062,2244,1160,1272]	6	hSpCas9	negative selection	6875285
15682884	15682907	12	+	27260156	G402	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.7132992967838752	[415]	[670,720,1050,851]	8	hSpCas9	negative selection	6875286
15670901	15670924	12	-	27260156	G402	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.5791984758954216	[328]	[607,568,573,642]	7	hSpCas9	negative selection	6939549
15682914	15682937	12	-	27260156	G402	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.5958739084533924	[707]	[1574,1210,1072,1387]	7	hSpCas9	negative selection	6939550
15669721	15669744	12	+	27260156	G402	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.6818340370572095	[269]	[492,570,573,473]	8	hSpCas9	negative selection	6939551
15669786	15669809	12	+	27260156	L33	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.18861834768736618	[1108]	[1379,490,727,1314]	4	hSpCas9	negative selection	6996535
15669804	15669827	12	-	27260156	L33	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.23008045548251643	[987]	[1155,434,791,1157]	5	hSpCas9	negative selection	6996536
15682884	15682907	12	+	27260156	L33	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.07365174368751787	[415]	[458,148,220,404]	-2	hSpCas9	negative selection	6996537
15670901	15670924	12	-	27260156	L33	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.1829673283433178	[328]	[318,181,268,304]	4	hSpCas9	negative selection	7060800
15682914	15682937	12	-	27260156	L33	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.044465806090823845	[707]	[687,268,505,771]	1	hSpCas9	negative selection	7060801
15669721	15669744	12	+	27260156	L33	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.3701440568924077	[269]	[171,86,136,233]	-7	hSpCas9	negative selection	7060802
15669786	15669809	12	+	27260156	K562	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.34927632758143323	[1108]	[1053,1708,1281,1001]	4	hSpCas9	negative selection	7117786
15669804	15669827	12	-	27260156	K562	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.7727353628084748	[987]	[1787,1941,1383,979]	8	hSpCas9	negative selection	7117787
15682884	15682907	12	+	27260156	K562	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.013498307820550587	[415]	[555,365,283,280]	0	hSpCas9	negative selection	7117788
15670901	15670924	12	-	27260156	K562	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.8847354477615919	[328]	[516,599,315,702]	9	hSpCas9	negative selection	7182051
15682914	15682937	12	-	27260156	K562	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.8216010118463388	[707]	[1178,924,1464,889]	9	hSpCas9	negative selection	7182052
15669721	15669744	12	+	27260156	K562	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.08815273527690592	[269]	[211,439,211,169]	1	hSpCas9	negative selection	7182053
15669786	15669809	12	+	27260156	HT29	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.0702805403782385	[1108]	[1683,1626,1240,1168]	1	hSpCas9	negative selection	7239037
15669804	15669827	12	-	27260156	HT29	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.34013590817825423	[987]	[1571,1758,1514,1278]	6	hSpCas9	negative selection	7239038
15682884	15682907	12	+	27260156	HT29	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.030429206239982992	[415]	[553,565,582,382]	0	hSpCas9	negative selection	7239039
15670901	15670924	12	-	27260156	HT29	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.006800622086705732	[328]	[446,496,323,353]	0	hSpCas9	negative selection	7303302
15682914	15682937	12	-	27260156	HT29	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.3187012491518948	[707]	[1212,1252,1104,777]	6	hSpCas9	negative selection	7303303
15669721	15669744	12	+	27260156	HT29	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.147817284649584	[269]	[417,317,485,244]	3	hSpCas9	negative selection	7303304
15669786	15669809	12	+	27260156	MHHES1	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.22673453213929173	[1108]	[1740,1625,1254,1281]	4	hSpCas9	negative selection	7360288
15669804	15669827	12	-	27260156	MHHES1	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.5805179691033828	[987]	[1835,1529,1943,1382]	8	hSpCas9	negative selection	7360289
15682884	15682907	12	+	27260156	MHHES1	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.4779054514012172	[415]	[433,990,529,647]	8	hSpCas9	negative selection	7360290
15670901	15670924	12	-	27260156	MHHES1	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.12198059530714866	[328]	[541,541,298,279]	2	hSpCas9	negative selection	7424553
15682914	15682937	12	-	27260156	MHHES1	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.31885015082010904	[707]	[1083,1305,938,730]	6	hSpCas9	negative selection	7424554
15669721	15669744	12	+	27260156	MHHES1	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.12349342579770739	[269]	[426,338,347,237]	2	hSpCas9	negative selection	7424555
15669786	15669809	12	+	27260156	MEWO	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.02072746224283617	[1108]	[1249,1025,835]	0	hSpCas9	negative selection	7481539
15669804	15669827	12	-	27260156	MEWO	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.3464672440416936	[987]	[1419,1149,1002]	7	hSpCas9	negative selection	7481540
15682884	15682907	12	+	27260156	MEWO	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.2812361601578601	[415]	[373,345,250]	-6	hSpCas9	negative selection	7481541
15670901	15670924	12	-	27260156	MEWO	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.07848177121050753	[328]	[284,365,315]	1	hSpCas9	negative selection	7545804
15682914	15682937	12	-	27260156	MEWO	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.3106681692814002	[707]	[922,837,722]	6	hSpCas9	negative selection	7545805
15669721	15669744	12	+	27260156	MEWO	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.21652839008213598	[269]	[333,162,177]	-5	hSpCas9	negative selection	7545806
15669786	15669809	12	+	27260156	LNCAPCLONEFGC	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.16510587178089686	[1108]	[1297,896,1249,1089]	2	hSpCas9	negative selection	7602790
15669804	15669827	12	-	27260156	LNCAPCLONEFGC	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.4353358391503468	[987]	[1353,1014,1235,1248]	6	hSpCas9	negative selection	7602791
15682884	15682907	12	+	27260156	LNCAPCLONEFGC	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.4538757708687145	[415]	[588,465,487,518]	7	hSpCas9	negative selection	7602792
15670901	15670924	12	-	27260156	LNCAPCLONEFGC	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.6143355194172927	[328]	[484,444,470,425]	8	hSpCas9	negative selection	7667055
15682914	15682937	12	-	27260156	LNCAPCLONEFGC	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.47176544631110695	[707]	[855,779,983,958]	7	hSpCas9	negative selection	7667056
15669721	15669744	12	+	27260156	LNCAPCLONEFGC	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.039706015027615615	[269]	[220,295,270,217]	0	hSpCas9	negative selection	7667057
15669786	15669809	12	+	27260156	PANC0327	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.05990756059529612	[1108]	[1064,1007,1080,958]	0	hSpCas9	negative selection	7724041
15669804	15669827	12	-	27260156	PANC0327	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.32599656756760154	[987]	[1066,1177,857,1283]	5	hSpCas9	negative selection	7724042
15682884	15682907	12	+	27260156	PANC0327	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.21969196183306658	[415]	[487,321,508,420]	3	hSpCas9	negative selection	7724043
15670901	15670924	12	-	27260156	PANC0327	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.4400299791805339	[328]	[414,180,401,616]	6	hSpCas9	negative selection	7788306
15682914	15682937	12	-	27260156	PANC0327	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.37336524864254694	[707]	[891,779,669,926]	5	hSpCas9	negative selection	7788307
15669721	15669744	12	+	27260156	PANC0327	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.012205070475210023	[269]	[290,349,146,152]	0	hSpCas9	negative selection	7788308
15669786	15669809	12	+	27260156	NCIH2009	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.4247794036109418	[1108]	[2182,2003,2070]	6	hSpCas9	negative selection	7845292
15669804	15669827	12	-	27260156	NCIH2009	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.5394852757042594	[987]	[2363,1746,1979]	7	hSpCas9	negative selection	7845293
15682884	15682907	12	+	27260156	NCIH2009	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.13482137390945972	[415]	[528,681,679]	1	hSpCas9	negative selection	7845294
15670901	15670924	12	-	27260156	NCIH2009	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.6829491111468609	[328]	[704,632,869]	8	hSpCas9	negative selection	7909557
15682914	15682937	12	-	27260156	NCIH2009	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.47207582972273454	[707]	[1869,1338,1003]	6	hSpCas9	negative selection	7909558
15669721	15669744	12	+	27260156	NCIH2009	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.12418869791585274	[269]	[367,240,434]	-2	hSpCas9	negative selection	7909559
15669786	15669809	12	+	27260156	NCIH1373	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.42634251427923053	[1108]	[1892,1494,1709,426]	4	hSpCas9	negative selection	7966543
15669804	15669827	12	-	27260156	NCIH1373	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.5337664713984664	[987]	[1294,1475,1788,477]	5	hSpCas9	negative selection	7966544
15682884	15682907	12	+	27260156	NCIH1373	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.46864080942783715	[415]	[1052,593,365,167]	4	hSpCas9	negative selection	7966545
15670901	15670924	12	-	27260156	NCIH1373	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.5126878193584582	[328]	[529,335,674,152]	5	hSpCas9	negative selection	8030808
15682914	15682937	12	-	27260156	NCIH1373	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.5656840390382611	[707]	[1137,1218,1120,316]	5	hSpCas9	negative selection	8030809
15669721	15669744	12	+	27260156	NCIH1373	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.2962952066439466	[269]	[309,417,438,77]	3	hSpCas9	negative selection	8030810
15669786	15669809	12	+	27260156	PATU8902	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.14679152594406109	[1108]	[2159,1400,1528,1784]	1	hSpCas9	negative selection	8087794
15669804	15669827	12	-	27260156	PATU8902	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.2936206111858224	[987]	[2295,1688,1202,1658]	3	hSpCas9	negative selection	8087795
15682884	15682907	12	+	27260156	PATU8902	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.022883531901589954	[415]	[481,817,578,459]	0	hSpCas9	negative selection	8087796
15670901	15670924	12	-	27260156	PATU8902	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.5172922837526506	[328]	[377,450,987,725]	5	hSpCas9	negative selection	8152059
15682914	15682937	12	-	27260156	PATU8902	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.22257738059115895	[707]	[1215,1190,909,1362]	2	hSpCas9	negative selection	8152060
15669721	15669744	12	+	27260156	PATU8902	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.4062071879158342	[269]	[165,216,306,458]	-4	hSpCas9	negative selection	8152061
15669786	15669809	12	+	27260156	PANC1	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.08859410445469229	[1108]	[1037,1346,907,837]	1	hSpCas9	negative selection	8209045
15669804	15669827	12	-	27260156	PANC1	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.1861192378728589	[987]	[899,1140,774,1050]	3	hSpCas9	negative selection	8209046
15682884	15682907	12	+	27260156	PANC1	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.1821809895919761	[415]	[412,563,342,337]	3	hSpCas9	negative selection	8209047
15670901	15670924	12	-	27260156	PANC1	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.38567400637064175	[328]	[213,668,382,283]	6	hSpCas9	negative selection	8273310
15682914	15682937	12	-	27260156	PANC1	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.25317466011999445	[707]	[849,706,839,518]	4	hSpCas9	negative selection	8273311
15669721	15669744	12	+	27260156	PANC1	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.33599718193048567	[269]	[163,260,153,170]	-5	hSpCas9	negative selection	8273312
15669786	15669809	12	+	27260156	PANC0813	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.33863666008084814	[1108]	[1783,1319,1585,1894]	5	hSpCas9	negative selection	8330296
15669804	15669827	12	-	27260156	PANC0813	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.4028852106162475	[987]	[1835,1435,1386,1504]	6	hSpCas9	negative selection	8330297
15682884	15682907	12	+	27260156	PANC0813	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.1715086655015035	[415]	[621,416,390,327]	-3	hSpCas9	negative selection	8330298
15670901	15670924	12	-	27260156	PANC0813	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.4478489178941224	[328]	[644,500,510,464]	7	hSpCas9	negative selection	8394561
15682914	15682937	12	-	27260156	PANC0813	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.4429274011259192	[707]	[1410,890,1196,1051]	7	hSpCas9	negative selection	8394562
15669721	15669744	12	+	27260156	PANC0813	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.0481965545411327	[269]	[263,409,256,291]	-1	hSpCas9	negative selection	8394563
15669786	15669809	12	+	27260156	RDES	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.007763375565411623	[1108]	[1156,1201,1298,1497]	0	hSpCas9	negative selection	8451547
15669804	15669827	12	-	27260156	RDES	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.3384297258260849	[987]	[1199,1255,1775,1572]	5	hSpCas9	negative selection	8451548
15682884	15682907	12	+	27260156	RDES	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.11333407118953868	[415]	[368,442,458,876]	1	hSpCas9	negative selection	8451549
15670901	15670924	12	-	27260156	RDES	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.19976033978454444	[328]	[414,404,457,456]	3	hSpCas9	negative selection	8515812
15682914	15682937	12	-	27260156	RDES	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.6038155244839116	[707]	[1028,1097,1413,1471]	8	hSpCas9	negative selection	8515813
15669721	15669744	12	+	27260156	RDES	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.11888069831682713	[269]	[348,339,383,248]	2	hSpCas9	negative selection	8515814
15669786	15669809	12	+	27260156	PC3	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.1025353205110493	[1108]	[698,784,1888,1137]	-2	hSpCas9	negative selection	8572798
15669804	15669827	12	-	27260156	PC3	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.17982826754281356	[987]	[782,1241,1487,1109]	4	hSpCas9	negative selection	8572799
15682884	15682907	12	+	27260156	PC3	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.02607215476325142	[415]	[259,496,872,252]	0	hSpCas9	negative selection	8572800
15670901	15670924	12	-	27260156	PC3	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.2698394616901274	[328]	[397,213,554,428]	6	hSpCas9	negative selection	8637063
15682914	15682937	12	-	27260156	PC3	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.1831481720045086	[707]	[379,1006,996,1015]	4	hSpCas9	negative selection	8637064
15669721	15669744	12	+	27260156	PC3	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.041262388107924486	[269]	[274,182,345,296]	0	hSpCas9	negative selection	8637065
15669786	15669809	12	+	27260156	PATU8988T	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.07741942642195321	[1108]	[1046,1140,876,1490]	1	hSpCas9	negative selection	8694049
15669804	15669827	12	-	27260156	PATU8988T	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.48870907781677975	[987]	[1516,1163,1126,1553]	7	hSpCas9	negative selection	8694050
15682884	15682907	12	+	27260156	PATU8988T	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.12368494732335066	[415]	[438,304,669,311]	2	hSpCas9	negative selection	8694051
15670901	15670924	12	-	27260156	PATU8988T	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.49529550429229346	[328]	[446,611,378,363]	8	hSpCas9	negative selection	8758314
15682914	15682937	12	-	27260156	PATU8988T	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.1910515236509407	[707]	[742,801,785,795]	3	hSpCas9	negative selection	8758315
15669721	15669744	12	+	27260156	PATU8988T	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.2386715166401152	[269]	[121,378,214,179]	-4	hSpCas9	negative selection	8758316
15669786	15669809	12	+	27260156	T47D	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.16371755436654767	[1108]	[1541,1317,1336,1609]	3	hSpCas9	negative selection	8815300
15669804	15669827	12	-	27260156	T47D	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.366699841351644	[987]	[1550,1343,1447,1609]	7	hSpCas9	negative selection	8815301
15682884	15682907	12	+	27260156	T47D	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.3678642342999676	[415]	[671,593,500,742]	7	hSpCas9	negative selection	8815302
15670901	15670924	12	-	27260156	T47D	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.3568158704933916	[328]	[442,453,592,473]	7	hSpCas9	negative selection	8879565
15682914	15682937	12	-	27260156	T47D	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.23096646770630846	[707]	[964,875,1010,1028]	5	hSpCas9	negative selection	8879566
15669721	15669744	12	+	27260156	T47D	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.32332325060126876	[269]	[391,375,399,407]	7	hSpCas9	negative selection	8879567
15669786	15669809	12	+	27260156	SU8686	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.2524575022079847	[1108]	[1194,1189,1291,1632]	4	hSpCas9	negative selection	8936551
15669804	15669827	12	-	27260156	SU8686	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.46318362523602086	[987]	[1195,1221,1482,1562]	7	hSpCas9	negative selection	8936552
15682884	15682907	12	+	27260156	SU8686	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.043608476984109995	[415]	[346,389,481,385]	-1	hSpCas9	negative selection	8936553
15670901	15670924	12	-	27260156	SU8686	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.5656000964451593	[328]	[390,349,491,768]	8	hSpCas9	negative selection	9000816
15682914	15682937	12	-	27260156	SU8686	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.42138969079634325	[707]	[879,775,1138,1001]	7	hSpCas9	negative selection	9000817
15669721	15669744	12	+	27260156	SU8686	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.2699447104215629	[269]	[184,314,213,152]	-4	hSpCas9	negative selection	9000818
15669786	15669809	12	+	27260156	SKES1	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.3566894378093506	[1108]	[1493,1780,1330,1134]	7	hSpCas9	negative selection	9057802
15669804	15669827	12	-	27260156	SKES1	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.2659855955643158	[987]	[1404,1365,1100,938]	5	hSpCas9	negative selection	9057803
15682884	15682907	12	+	27260156	SKES1	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.0752646784000397	[415]	[348,512,299,415]	-2	hSpCas9	negative selection	9057804
15670901	15670924	12	-	27260156	SKES1	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.17814654059064539	[328]	[342,417,399,326]	4	hSpCas9	negative selection	9122067
15682914	15682937	12	-	27260156	SKES1	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.14716525419977344	[707]	[880,727,758,761]	3	hSpCas9	negative selection	9122068
15669721	15669744	12	+	27260156	SKES1	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.14263452559976375	[269]	[310,308,274,294]	3	hSpCas9	negative selection	9122069
15669786	15669809	12	+	27260156	TOV112D	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.32467681340810084	[1108]	[1432,1745,1199,1276]	6	hSpCas9	negative selection	9179053
15669804	15669827	12	-	27260156	TOV112D	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.20682083331617274	[987]	[1271,896,1097,1246]	4	hSpCas9	negative selection	9179054
15682884	15682907	12	+	27260156	TOV112D	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.08421259178842783	[415]	[349,543,282,426]	-2	hSpCas9	negative selection	9179055
15670901	15670924	12	-	27260156	TOV112D	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.654944899527678	[328]	[617,556,571,349]	9	hSpCas9	negative selection	9243318
15682914	15682937	12	-	27260156	TOV112D	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.27056023301824905	[707]	[777,891,985,768]	5	hSpCas9	negative selection	9243319
15669721	15669744	12	+	27260156	TOV112D	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	0.28599191076064834	[269]	[257,230,325,468]	5	hSpCas9	negative selection	9243320
15669786	15669809	12	+	27260156	TC71	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	-0.007832478487755923	[1108]	[1178,1153,1116,1287]	0	hSpCas9	negative selection	9300304
15669804	15669827	12	-	27260156	TC71	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.18747389756669386	[987]	[1000,1215,1113,1519]	5	hSpCas9	negative selection	9300305
15682884	15682907	12	+	27260156	TC71	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	-0.029508268888845723	[415]	[365,511,366,510]	0	hSpCas9	negative selection	9300306
15670901	15670924	12	-	27260156	TC71	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	-0.024239544122439893	[328]	[329,348,301,411]	0	hSpCas9	negative selection	9364569
15682914	15682937	12	-	27260156	TC71	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.1085058943585201	[707]	[736,1029,769,733]	2	hSpCas9	negative selection	9364570
15669721	15669744	12	+	27260156	TC71	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.10616445391544027	[269]	[308,298,208,258]	-3	hSpCas9	negative selection	9364571
15669786	15669809	12	+	27260156	TC32	viability	TCATAGCATCTTTCCGATCCAGG	EPS8	ENSG00000151491	0.08364753180421558	[1108]	[1078,661,1799,1105]	1	hSpCas9	negative selection	9421555
15669804	15669827	12	-	27260156	TC32	viability	GCACTTGACTACCTTTGTCCTGG	EPS8	ENSG00000151491	0.3027122137276197	[987]	[1127,770,1396,1420]	5	hSpCas9	negative selection	9421556
15682884	15682907	12	+	27260156	TC32	viability	TCAACTTACTTCATCTGAGATGG	EPS8	ENSG00000151491	0.32794850109917817	[415]	[399,407,584,605]	6	hSpCas9	negative selection	9421557
15670901	15670924	12	-	27260156	TC32	viability	AACAAAGGAAGAATTATGCACGG	EPS8	ENSG00000151491	0.1991524891408819	[328]	[363,141,470,533]	3	hSpCas9	negative selection	9485820
15682914	15682937	12	-	27260156	TC32	viability	TCTAATCATCCCAGTAGTTTTGG	EPS8	ENSG00000151491	0.47387316211714703	[707]	[859,757,1133,998]	7	hSpCas9	negative selection	9485821
15669721	15669744	12	+	27260156	TC32	viability	TTGAGTCCACACTTTGCCCTTGG	EPS8	ENSG00000151491	-0.029324311168360873	[269]	[296,152,197,358]	0	hSpCas9	negative selection	9485822
15650846	15650869	12	-	27869803	HPAFII	viability after 27 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	1.0181621588997214	[382]	[505,325,NaN]	8	hSpCas9	negative selection	9546181
15654274	15654297	12	-	27869803	HPAFII	viability after 27 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.4300807949048868	[311]	[315,546,NaN]	9	hSpCas9	negative selection	9546182
15662070	15662093	12	-	27869803	HPAFII	viability after 27 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.47100848987764676	[188]	[128,144,NaN]	4	hSpCas9	negative selection	9546183
15665760	15665783	12	-	27869803	HPAFII	viability after 27 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.53435441480831	[184]	[248,308,NaN]	9	hSpCas9	negative selection	9546184
15666470	15666493	12	-	27869803	HPAFII	viability after 27 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.7100587034512549	[568]	[370,587,NaN]	6	hSpCas9	negative selection	9546185
15669793	15669816	12	+	27869803	HPAFII	viability after 27 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	1.120535800438057	[316]	[255,450,NaN]	8	hSpCas9	negative selection	9546186
15650846	15650869	12	-	27869803	HPAFII	viability after 15 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.6040905061491273	[382]	[867,474,NaN]	7	hSpCas9	negative selection	9628630
15654274	15654297	12	-	27869803	HPAFII	viability after 15 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.25529511464413346	[311]	[673,229,NaN]	3	hSpCas9	negative selection	9628631
15662070	15662093	12	-	27869803	HPAFII	viability after 15 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.3307532565576714	[188]	[215,279,NaN]	4	hSpCas9	negative selection	9628632
15665760	15665783	12	-	27869803	HPAFII	viability after 15 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.9031725482496037	[184]	[414,344,NaN]	8	hSpCas9	negative selection	9628633
15666470	15666493	12	-	27869803	HPAFII	viability after 15 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.573054601657393	[568]	[1349,635,NaN]	6	hSpCas9	negative selection	9628634
15669793	15669816	12	+	27869803	HPAFII	viability after 15 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.15484327044902557	[316]	[620,228,NaN]	1	hSpCas9	negative selection	9628635
15650846	15650869	12	-	27869803	ASPC1	viability after 36 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.5655419349351686	[1046]	[672,111,782]	5	hSpCas9	negative selection	9711079
15654274	15654297	12	-	27869803	ASPC1	viability after 36 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.1873512268130075	[665]	[930,346,386]	9	hSpCas9	negative selection	9711080
15662070	15662093	12	-	27869803	ASPC1	viability after 36 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	1.8009155631563307	[491]	[446,807,531]	9	hSpCas9	negative selection	9711081
15665760	15665783	12	-	27869803	ASPC1	viability after 36 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	-1.2179546090110738	[539]	[93,94,59]	-8	hSpCas9	negative selection	9711082
15666470	15666493	12	-	27869803	ASPC1	viability after 36 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.6529263808706287	[1418]	[1427,564,484]	6	hSpCas9	negative selection	9711083
15669793	15669816	12	+	27869803	ASPC1	viability after 36 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	1.009443217955237	[713]	[340,753,408]	8	hSpCas9	negative selection	9711084
15650846	15650869	12	-	27869803	PATU8988S	viability after 35 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	-0.23056952379456686	[1027]	[297,407,NaN]	-2	hSpCas9	negative selection	9793528
15654274	15654297	12	-	27869803	PATU8988S	viability after 35 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.7373480757355364	[763]	[215,152,NaN]	-6	hSpCas9	negative selection	9793529
15662070	15662093	12	-	27869803	PATU8988S	viability after 35 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.04494333219935631	[300]	[152,96,NaN]	0	hSpCas9	negative selection	9793530
15665760	15665783	12	-	27869803	PATU8988S	viability after 35 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.1396125944761859	[364]	[135,187,NaN]	1	hSpCas9	negative selection	9793531
15666470	15666493	12	-	27869803	PATU8988S	viability after 35 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.00693964255338253	[1313]	[602,449,NaN]	0	hSpCas9	negative selection	9793532
15669793	15669816	12	+	27869803	PATU8988S	viability after 35 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.5189087080978338	[569]	[302,354,NaN]	6	hSpCas9	negative selection	9793533
15650846	15650869	12	-	27869803	PATU8988S	viability after 31 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	0.03367764553528352	[1027]	[368,483,NaN]	0	hSpCas9	negative selection	9875977
15654274	15654297	12	-	27869803	PATU8988S	viability after 31 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.2713598376565259	[763]	[280,215,NaN]	-3	hSpCas9	negative selection	9875978
15662070	15662093	12	-	27869803	PATU8988S	viability after 31 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.2337439292725505	[300]	[196,69,NaN]	3	hSpCas9	negative selection	9875979
15665760	15665783	12	-	27869803	PATU8988S	viability after 31 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	0.19347385516666293	[364]	[110,236,NaN]	2	hSpCas9	negative selection	9875980
15666470	15666493	12	-	27869803	PATU8988S	viability after 31 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.2230022038685473	[1313]	[396,514,NaN]	-3	hSpCas9	negative selection	9875981
15669793	15669816	12	+	27869803	PATU8988S	viability after 31 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	0.5507916523753095	[569]	[262,421,NaN]	6	hSpCas9	negative selection	9875982
15650846	15650869	12	-	27869803	HPAFII	viability after 35 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	1.4668707704436337	[382]	[455,625,NaN]	8	hSpCas9	negative selection	9958426
15654274	15654297	12	-	27869803	HPAFII	viability after 35 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.9544002548727544	[311]	[296,966,NaN]	9	hSpCas9	negative selection	9958427
15662070	15662093	12	-	27869803	HPAFII	viability after 35 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.8482642342261146	[188]	[96,256,NaN]	5	hSpCas9	negative selection	9958428
15665760	15665783	12	-	27869803	HPAFII	viability after 35 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.7239406380109181	[184]	[124,516,NaN]	9	hSpCas9	negative selection	9958429
15666470	15666493	12	-	27869803	HPAFII	viability after 35 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.1510366639897058	[568]	[491,805,NaN]	7	hSpCas9	negative selection	9958430
15669793	15669816	12	+	27869803	HPAFII	viability after 35 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	1.2830669799213155	[316]	[287,505,NaN]	8	hSpCas9	negative selection	9958431
15650846	15650869	12	-	27869803	HPAFII	viability after 31 days	AGCAGAACATCAGCGCAAACAGG	EPS8	ENSG00000151491	1.0249093474102757	[382]	[389,488,NaN]	7	hSpCas9	negative selection	10040875
15654274	15654297	12	-	27869803	HPAFII	viability after 31 days	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.4359728656116073	[311]	[378,576,NaN]	9	hSpCas9	negative selection	10040876
15662070	15662093	12	-	27869803	HPAFII	viability after 31 days	ACCAAGGCAGTATCATGAGCAGG	EPS8	ENSG00000151491	0.4507535625731578	[188]	[54,242,NaN]	3	hSpCas9	negative selection	10040877
15665760	15665783	12	-	27869803	HPAFII	viability after 31 days	CTGCATGGGCAGCCGACCAAGGG	EPS8	ENSG00000151491	1.6329706218449396	[184]	[232,418,NaN]	9	hSpCas9	negative selection	10040878
15666470	15666493	12	-	27869803	HPAFII	viability after 31 days	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.0964810646118877	[568]	[466,917,NaN]	7	hSpCas9	negative selection	10040879
15669793	15669816	12	+	27869803	HPAFII	viability after 31 days	ATCTTTCCGATCCAGGACAAAGG	EPS8	ENSG00000151491	1.0046392304864193	[316]	[288,430,NaN]	7	hSpCas9	negative selection	10040880
15631445	15631468	12	-	28162770	P31FUJ	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	1.8826750130055574	[2]	[12]	9	hSpCas9	negative selection	10150804
15640820	15640843	12	-	28162770	P31FUJ	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.8927286776694803	[340]	[743]	8	hSpCas9	negative selection	10150805
15666470	15666493	12	-	28162770	P31FUJ	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.9464980192577375	[122]	[74]	-6	hSpCas9	negative selection	10150806
15666457	15666480	12	-	28162770	P31FUJ	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.3522658710159502	[301]	[277]	-3	hSpCas9	negative selection	10150807
15654274	15654297	12	-	28162770	P31FUJ	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.195807996932177	[384]	[394]	-2	hSpCas9	negative selection	10150808
15647226	15647249	12	-	28162770	P31FUJ	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.13856482320748864	[326]	[422]	1	hSpCas9	negative selection	10150809
15660613	15660636	12	-	28162770	P31FUJ	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.6968084676942237	[20]	[39]	7	hSpCas9	negative selection	10150810
15654177	15654200	12	-	28162770	P31FUJ	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.37773654301279375	[204]	[312]	4	hSpCas9	negative selection	10150811
15647175	15647198	12	-	28162770	P31FUJ	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.4892280263542932	[601]	[992]	5	hSpCas9	negative selection	10150812
15647158	15647181	12	+	28162770	P31FUJ	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.6501231782701289	[865]	[1596]	7	hSpCas9	negative selection	10150813
15631445	15631468	12	-	28162770	TF1	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10320170
15640820	15640843	12	-	28162770	TF1	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10320171
15666470	15666493	12	-	28162770	TF1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10320172
15666457	15666480	12	-	28162770	TF1	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10320173
15654274	15654297	12	-	28162770	TF1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10320174
15647226	15647249	12	-	28162770	TF1	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10320175
15660613	15660636	12	-	28162770	TF1	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10320176
15654177	15654200	12	-	28162770	TF1	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10320177
15647175	15647198	12	-	28162770	TF1	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	NaN	[NaN]	[814]	1	hSpCas9	negative selection	10320178
15647158	15647181	12	+	28162770	TF1	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	NaN	[NaN]	[1133]	1	hSpCas9	negative selection	10320179
15631445	15631468	12	-	28162770	SKM1	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10489536
15640820	15640843	12	-	28162770	SKM1	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.19507181533693596	[83]	[169]	2	hSpCas9	negative selection	10489537
15666470	15666493	12	-	28162770	SKM1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.24511249783653155	[20]	[43]	2	hSpCas9	negative selection	10489538
15666457	15666480	12	-	28162770	SKM1	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.1590366852995762	[71]	[113]	-1	hSpCas9	negative selection	10489539
15654274	15654297	12	-	28162770	SKM1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.22479251345693563	[90]	[187]	2	hSpCas9	negative selection	10489540
15647226	15647249	12	-	28162770	SKM1	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.1779983019779946	[88]	[177]	1	hSpCas9	negative selection	10489541
15660613	15660636	12	-	28162770	SKM1	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.9149638961442004	[2]	[9]	8	hSpCas9	negative selection	10489542
15654177	15654200	12	-	28162770	SKM1	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.05246741989413554	[53]	[98]	0	hSpCas9	negative selection	10489543
15647175	15647198	12	-	28162770	SKM1	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.6532404354627537	[131]	[366]	6	hSpCas9	negative selection	10489544
15647158	15647181	12	+	28162770	SKM1	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.5765476784682693	[175]	[463]	5	hSpCas9	negative selection	10489545
15631445	15631468	12	-	28162770	SKM1	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-2.406964198743162	[2]	[0]	-8	hSpCas9	negative selection	10658902
15640820	15640843	12	-	28162770	SKM1	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.19507181533693596	[83]	[169]	2	hSpCas9	negative selection	10658903
15666470	15666493	12	-	28162770	SKM1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.24511249783653155	[20]	[43]	2	hSpCas9	negative selection	10658904
15666457	15666480	12	-	28162770	SKM1	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.1590366852995762	[71]	[113]	-1	hSpCas9	negative selection	10658905
15654274	15654297	12	-	28162770	SKM1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.22479251345693563	[90]	[187]	2	hSpCas9	negative selection	10658906
15647226	15647249	12	-	28162770	SKM1	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.1779983019779946	[88]	[177]	1	hSpCas9	negative selection	10658907
15660613	15660636	12	-	28162770	SKM1	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.9149638961442004	[2]	[9]	8	hSpCas9	negative selection	10658908
15654177	15654200	12	-	28162770	SKM1	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.05246741989413554	[53]	[98]	0	hSpCas9	negative selection	10658909
15647175	15647198	12	-	28162770	SKM1	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.6532404354627537	[131]	[366]	6	hSpCas9	negative selection	10658910
15647158	15647181	12	+	28162770	SKM1	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.5765476784682693	[175]	[463]	5	hSpCas9	negative selection	10658911
15631445	15631468	12	-	28162770	PL21	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-0.7998603855106801	[7]	[1]	-5	hSpCas9	negative selection	10828268
15640820	15640843	12	-	28162770	PL21	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.30416267903254846	[213]	[114]	2	hSpCas9	negative selection	10828269
15666470	15666493	12	-	28162770	PL21	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.03412966305039089	[91]	[40]	0	hSpCas9	negative selection	10828270
15666457	15666480	12	-	28162770	PL21	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.8184760636780268	[311]	[76]	-5	hSpCas9	negative selection	10828271
15654274	15654297	12	-	28162770	PL21	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.20039831509440853	[329]	[124]	-1	hSpCas9	negative selection	10828272
15647226	15647249	12	-	28162770	PL21	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.8006227005468542	[338]	[256]	7	hSpCas9	negative selection	10828273
15660613	15660636	12	-	28162770	PL21	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-0.04778789895426527	[18]	[7]	0	hSpCas9	negative selection	10828274
15654177	15654200	12	-	28162770	PL21	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	-1.5242259428972522	[151]	[22]	-7	hSpCas9	negative selection	10828275
15647175	15647198	12	-	28162770	PL21	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.9558711858219386	[442]	[373]	7	hSpCas9	negative selection	10828276
15647158	15647181	12	+	28162770	PL21	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.7541775420155756	[612]	[449]	6	hSpCas9	negative selection	10828277
15631445	15631468	12	-	28162770	P31FUJ	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	1.8826750130055574	[2]	[12]	9	hSpCas9	negative selection	10997634
15640820	15640843	12	-	28162770	P31FUJ	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.8927286776694803	[340]	[743]	8	hSpCas9	negative selection	10997635
15666470	15666493	12	-	28162770	P31FUJ	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.9464980192577375	[122]	[74]	-6	hSpCas9	negative selection	10997636
15666457	15666480	12	-	28162770	P31FUJ	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.3522658710159502	[301]	[277]	-3	hSpCas9	negative selection	10997637
15654274	15654297	12	-	28162770	P31FUJ	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	-0.195807996932177	[384]	[394]	-2	hSpCas9	negative selection	10997638
15647226	15647249	12	-	28162770	P31FUJ	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.13856482320748864	[326]	[422]	1	hSpCas9	negative selection	10997639
15660613	15660636	12	-	28162770	P31FUJ	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.6968084676942237	[20]	[39]	7	hSpCas9	negative selection	10997640
15654177	15654200	12	-	28162770	P31FUJ	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.37773654301279375	[204]	[312]	4	hSpCas9	negative selection	10997641
15647175	15647198	12	-	28162770	P31FUJ	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.4892280263542932	[601]	[992]	5	hSpCas9	negative selection	10997642
15647158	15647181	12	+	28162770	P31FUJ	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.6501231782701289	[865]	[1596]	7	hSpCas9	negative selection	10997643
15631445	15631468	12	-	28162770	OCIAML5	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	2.3703258504724505	[2]	[27]	9	hSpCas9	negative selection	11167000
15640820	15640843	12	-	28162770	OCIAML5	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-0.16427951091814763	[184]	[297]	-1	hSpCas9	negative selection	11167001
15666470	15666493	12	-	28162770	OCIAML5	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.6564828143379913	[41]	[238]	9	hSpCas9	negative selection	11167002
15666457	15666480	12	-	28162770	OCIAML5	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	0.05482402474452164	[167]	[314]	0	hSpCas9	negative selection	11167003
15654274	15654297	12	-	28162770	OCIAML5	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.5333109548946073	[128]	[336]	4	hSpCas9	negative selection	11167004
15647226	15647249	12	-	28162770	OCIAML5	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	-0.1168614345622282	[163]	[272]	-1	hSpCas9	negative selection	11167005
15660613	15660636	12	-	28162770	OCIAML5	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	1.054824024744522	[3]	[14]	8	hSpCas9	negative selection	11167006
15654177	15654200	12	-	28162770	OCIAML5	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	-0.7410352584752531	[124]	[134]	-5	hSpCas9	negative selection	11167007
15647175	15647198	12	-	28162770	OCIAML5	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.3439712708974465	[291]	[668]	3	hSpCas9	negative selection	11167008
15647158	15647181	12	+	28162770	OCIAML5	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.560626987946548	[461]	[1229]	5	hSpCas9	negative selection	11167009
15631445	15631468	12	-	28162770	EOL1	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-1.7193084182041902	[24]	[3]	-8	hSpCas9	negative selection	11336366
15640820	15640843	12	-	28162770	EOL1	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.08616595389230589	[328]	[183]	0	hSpCas9	negative selection	11336367
15666470	15666493	12	-	28162770	EOL1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.4408686066865601	[164]	[235]	9	hSpCas9	negative selection	11336368
15666457	15666480	12	-	28162770	EOL1	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.6250093930194229	[482]	[164]	-4	hSpCas9	negative selection	11336369
15654274	15654297	12	-	28162770	EOL1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.16555587107432956	[571]	[337]	1	hSpCas9	negative selection	11336370
15647226	15647249	12	-	28162770	EOL1	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.2840901582576747	[582]	[373]	2	hSpCas9	negative selection	11336371
15660613	15660636	12	-	28162770	EOL1	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-2.5348838470667627	[21]	[1]	-8	hSpCas9	negative selection	11336372
15654177	15654200	12	-	28162770	EOL1	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	-0.08165737795617373	[232]	[115]	0	hSpCas9	negative selection	11336373
15647175	15647198	12	-	28162770	EOL1	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.5102746140530867	[628]	[471]	4	hSpCas9	negative selection	11336374
15647158	15647181	12	+	28162770	EOL1	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.6424282418969025	[973]	[800]	6	hSpCas9	negative selection	11336375
15631445	15631468	12	-	28162770	MOLM13	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	1.467889381544579	[8]	[17]	9	hSpCas9	negative selection	11505732
15640820	15640843	12	-	28162770	MOLM13	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-1.3679912386943145	[331]	[92]	-6	hSpCas9	negative selection	11505733
15666470	15666493	12	-	28162770	MOLM13	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	1.3346228506811146	[118]	[216]	8	hSpCas9	negative selection	11505734
15666457	15666480	12	-	28162770	MOLM13	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-1.0312123825227395	[423]	[149]	-5	hSpCas9	negative selection	11505735
15654274	15654297	12	-	28162770	MOLM13	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.5158836631574173	[472]	[488]	4	hSpCas9	negative selection	11505736
15647226	15647249	12	-	28162770	MOLM13	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.3426699957462631	[420]	[385]	2	hSpCas9	negative selection	11505737
15660613	15660636	12	-	28162770	MOLM13	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-0.4251954145389094	[12]	[6]	-3	hSpCas9	negative selection	11505738
15654177	15654200	12	-	28162770	MOLM13	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	1.3808326472753556	[221]	[417]	9	hSpCas9	negative selection	11505739
15647175	15647198	12	-	28162770	MOLM13	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	-0.3545724329032336	[671]	[379]	-2	hSpCas9	negative selection	11505740
15647158	15647181	12	+	28162770	MOLM13	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.7245749804349046	[872]	[1042]	5	hSpCas9	negative selection	11505741
15631445	15631468	12	-	28162770	HEL	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	1.0053089113850646	[6]	[8]	8	hSpCas9	negative selection	11675098
15640820	15640843	12	-	28162770	HEL	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.6371793066584563	[259]	[258]	5	hSpCas9	negative selection	11675099
15666470	15666493	12	-	28162770	HEL	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.21413622590104575	[162]	[89]	-1	hSpCas9	negative selection	11675100
15666457	15666480	12	-	28162770	HEL	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.8255406885554665	[367]	[132]	-5	hSpCas9	negative selection	11675101
15654274	15654297	12	-	28162770	HEL	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	1.2675466682465428	[368]	[568]	9	hSpCas9	negative selection	11675102
15647226	15647249	12	-	28162770	HEL	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.8233110776421779	[359]	[407]	7	hSpCas9	negative selection	11675103
15660613	15660636	12	-	28162770	HEL	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-1.2317302859157842	[10]	[2]	-6	hSpCas9	negative selection	11675104
15654177	15654200	12	-	28162770	HEL	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.12313006927330045	[204]	[142]	1	hSpCas9	negative selection	11675105
15647175	15647198	12	-	28162770	HEL	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.4280959102688435	[556]	[479]	3	hSpCas9	negative selection	11675106
15647158	15647181	12	+	28162770	HEL	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.11266808977527298	[721]	[499]	0	hSpCas9	negative selection	11675107
15631445	15631468	12	-	28162770	MV411	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-2.3375249499383806	[5]	[0]	-8	hSpCas9	negative selection	11844464
15640820	15640843	12	-	28162770	MV411	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-0.28158677834452334	[214]	[148]	-2	hSpCas9	negative selection	11844465
15666470	15666493	12	-	28162770	MV411	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.9195520005990135	[90]	[144]	8	hSpCas9	negative selection	11844466
15666457	15666480	12	-	28162770	MV411	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	0.017740328823094176	[230]	[196]	0	hSpCas9	negative selection	11844467
15654274	15654297	12	-	28162770	MV411	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.8515088744516363	[299]	[455]	7	hSpCas9	negative selection	11844468
15647226	15647249	12	-	28162770	MV411	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.42055223966388583	[250]	[282]	4	hSpCas9	negative selection	11844469
15660613	15660636	12	-	28162770	MV411	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	1.3994406442278247	[8]	[19]	9	hSpCas9	negative selection	11844470
15654177	15654200	12	-	28162770	MV411	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	-0.5799829943289345	[180]	[101]	-4	hSpCas9	negative selection	11844471
15647175	15647198	12	-	28162770	MV411	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.3790148089335563	[376]	[412]	3	hSpCas9	negative selection	11844472
15647158	15647181	12	+	28162770	MV411	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.2622998827906815	[675]	[682]	2	hSpCas9	negative selection	11844473
15631445	15631468	12	-	28162770	MONOMAC1	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-1.78199934778071	[5]	[1]	-8	hSpCas9	negative selection	12013830
15640820	15640843	12	-	28162770	MONOMAC1	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	-0.7475893169948786	[144]	[98]	-6	hSpCas9	negative selection	12013831
15666470	15666493	12	-	28162770	MONOMAC1	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	0.12977346920755473	[58]	[73]	1	hSpCas9	negative selection	12013832
15666457	15666480	12	-	28162770	MONOMAC1	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.7994444822401192	[207]	[136]	-6	hSpCas9	negative selection	12013833
15654274	15654297	12	-	28162770	MONOMAC1	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.45296477538909397	[252]	[396]	4	hSpCas9	negative selection	12013834
15647226	15647249	12	-	28162770	MONOMAC1	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.433440312913971	[207]	[321]	4	hSpCas9	negative selection	12013835
15660613	15660636	12	-	28162770	MONOMAC1	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.6509600594953961	[4]	[8]	6	hSpCas9	negative selection	12013836
15654177	15654200	12	-	28162770	MONOMAC1	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.7499447706409554	[96]	[186]	7	hSpCas9	negative selection	12013837
15647175	15647198	12	-	28162770	MONOMAC1	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.8116280140675738	[248]	[500]	7	hSpCas9	negative selection	12013838
15647158	15647181	12	+	28162770	MONOMAC1	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.21723141997451934	[468]	[624]	2	hSpCas9	negative selection	12013839
15631445	15631468	12	-	28162770	OCIAML2	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-1.1487017303547988	[1]	[4]	-6	hSpCas9	negative selection	12183196
15640820	15640843	12	-	28162770	OCIAML2	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	1.08001831095366	[38]	[456]	8	hSpCas9	negative selection	12183197
15666470	15666493	12	-	28162770	OCIAML2	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.06853138167081568	[27]	[147]	0	hSpCas9	negative selection	12183198
15666457	15666480	12	-	28162770	OCIAML2	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.6066913748181897	[49]	[181]	-4	hSpCas9	negative selection	12183199
15654274	15654297	12	-	28162770	OCIAML2	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.31853198004947325	[56]	[393]	3	hSpCas9	negative selection	12183200
15647226	15647249	12	-	28162770	OCIAML2	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.035402206257275415	[71]	[408]	0	hSpCas9	negative selection	12183201
15660613	15660636	12	-	28162770	OCIAML2	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	-2.956056652412403	[6]	[4]	-9	hSpCas9	negative selection	12183202
15654177	15654200	12	-	28162770	OCIAML2	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	0.034898207984589924	[27]	[158]	0	hSpCas9	negative selection	12183203
15647175	15647198	12	-	28162770	OCIAML2	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	0.055580088194905786	[70]	[408]	0	hSpCas9	negative selection	12183204
15647158	15647181	12	+	28162770	OCIAML2	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.48699157248728686	[94]	[737]	5	hSpCas9	negative selection	12183205
15631445	15631468	12	-	28162770	OCIAML3	viability	GAGACACAAACAACTTCCGGTGG	EPS8	ENSG00000151491	-1.594007640324163	[1]	[1]	-8	hSpCas9	negative selection	12352562
15640820	15640843	12	-	28162770	OCIAML3	viability	TTGATGATCGGAAGCAATGGTGG	EPS8	ENSG00000151491	0.34940883130946937	[51]	[199]	3	hSpCas9	negative selection	12352563
15666470	15666493	12	-	28162770	OCIAML3	viability	GCAATCAGTGACAGTAAAGGAGG	EPS8	ENSG00000151491	-0.22477383065844392	[35]	[92]	-2	hSpCas9	negative selection	12352564
15666457	15666480	12	-	28162770	OCIAML3	viability	GTAAAGGAGGGAAACAGAAGAGG	EPS8	ENSG00000151491	-0.30860542146191494	[79]	[194]	-2	hSpCas9	negative selection	12352565
15654274	15654297	12	-	28162770	OCIAML3	viability	TAGGTGGTGCAGGCAACAGGAGG	EPS8	ENSG00000151491	0.015532883117658991	[96]	[295]	0	hSpCas9	negative selection	12352566
15647226	15647249	12	-	28162770	OCIAML3	viability	TCAGAGTATCATCCAGCCGATGG	EPS8	ENSG00000151491	0.18128607250114248	[77]	[266]	1	hSpCas9	negative selection	12352567
15660613	15660636	12	-	28162770	OCIAML3	viability	GGTAAAAGGAAAGGACCAGGAGG	EPS8	ENSG00000151491	0.7279204545631992	[3]	[19]	6	hSpCas9	negative selection	12352568
15654177	15654200	12	-	28162770	OCIAML3	viability	ATGGTGATGAACGGCAGCTGTGG	EPS8	ENSG00000151491	-0.03107144593300598	[43]	[129]	0	hSpCas9	negative selection	12352569
15647175	15647198	12	-	28162770	OCIAML3	viability	AGAGGATCCCACCTGGACCAAGG	EPS8	ENSG00000151491	-0.08525570622312562	[148]	[423]	0	hSpCas9	negative selection	12352570
15647158	15647181	12	+	28162770	OCIAML3	viability	AAGCAACAGCAGCTTCCCCTTGG	EPS8	ENSG00000151491	0.743602076795469	[182]	[924]	6	hSpCas9	negative selection	12352571