Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 64787
• Symbol: EPS8L2
• Description: EPS8 signaling adaptor L2

DataSource: http://genomecrispr.dkfz.de/#!/results/EPS8L2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
694999	695022	11	-	26472758	Jiyoye	viability	GCAGCTGGGCCTGGCTGAGGCGG	EPS8L2	ENSG00000177106	-1.6923602920450411	[179]	[41]	-8	hSpCas9	negative selection	42528
694900	694923	11	-	26472758	Jiyoye	viability	GAGCAGGGACGAGGACTCGGAGG	EPS8L2	ENSG00000177106	-1.030229930801425	[64]	[23]	-6	hSpCas9	negative selection	42530
694882	694905	11	-	26472758	Jiyoye	viability	GGAGGAGGACGCAGACTCGGAGG	EPS8L2	ENSG00000177106	1.5727614472238485	[73]	[165]	8	hSpCas9	negative selection	42531
694834	694857	11	-	26472758	Jiyoye	viability	GGCAGTGGCGGTGATGGCGGCGG	EPS8L2	ENSG00000177106	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	42533
694813	694836	11	-	26472758	Jiyoye	viability	GGAGCCCGGGCACATGGACATGG	EPS8L2	ENSG00000177106	0.05784112927785928	[92]	[72]	0	hSpCas9	negative selection	42534
694751	694774	11	+	26472758	Jiyoye	viability	GCACTTGCCTGCGAAGGCTGCGG	EPS8L2	ENSG00000177106	-0.3726988041296237	[90]	[52]	-3	hSpCas9	negative selection	42535
694999	695022	11	-	26472758	KBM7	viability	GCAGCTGGGCCTGGCTGAGGCGG	EPS8L2	ENSG00000177106	-2.0335221647079154	[558,370]	[41,61]	-8	hSpCas9	negative selection	233646
694900	694923	11	-	26472758	KBM7	viability	GAGCAGGGACGAGGACTCGGAGG	EPS8L2	ENSG00000177106	-0.4605992449073133	[119,83]	[26,40]	-4	hSpCas9	negative selection	233648
694882	694905	11	-	26472758	KBM7	viability	GGAGGAGGACGCAGACTCGGAGG	EPS8L2	ENSG00000177106	0.24623203156191203	[784,420]	[288,361]	2	hSpCas9	negative selection	233649
694834	694857	11	-	26472758	KBM7	viability	GGCAGTGGCGGTGATGGCGGCGG	EPS8L2	ENSG00000177106	-2.884995328167963	[24,7]	[0,0]	-9	hSpCas9	negative selection	233651
694813	694836	11	-	26472758	KBM7	viability	GGAGCCCGGGCACATGGACATGG	EPS8L2	ENSG00000177106	0.34003537132842976	[340,288]	[114,250]	3	hSpCas9	negative selection	233652
694751	694774	11	+	26472758	KBM7	viability	GCACTTGCCTGCGAAGGCTGCGG	EPS8L2	ENSG00000177106	-0.5684247580687694	[711,571]	[196,206]	-5	hSpCas9	negative selection	233653
694999	695022	11	-	26472758	Raji	viability	GCAGCTGGGCCTGGCTGAGGCGG	EPS8L2	ENSG00000177106	-2.937010583984854	[197]	[5]	-9	hSpCas9	negative selection	424764
694900	694923	11	-	26472758	Raji	viability	GAGCAGGGACGAGGACTCGGAGG	EPS8L2	ENSG00000177106	0.10738353537359968	[51]	[12]	1	hSpCas9	negative selection	424766
694882	694905	11	-	26472758	Raji	viability	GGAGGAGGACGCAGACTCGGAGG	EPS8L2	ENSG00000177106	-0.15017574039404324	[262]	[54]	-1	hSpCas9	negative selection	424767
694834	694857	11	-	26472758	Raji	viability	GGCAGTGGCGGTGATGGCGGCGG	EPS8L2	ENSG00000177106	-1.7995070602349195	[14]	[0]	-8	hSpCas9	negative selection	424769
694813	694836	11	-	26472758	Raji	viability	GGAGCCCGGGCACATGGACATGG	EPS8L2	ENSG00000177106	-0.4775789653475566	[209]	[34]	-4	hSpCas9	negative selection	424770
694751	694774	11	+	26472758	Raji	viability	GCACTTGCCTGCGAAGGCTGCGG	EPS8L2	ENSG00000177106	-0.6520766965796931	[236]	[34]	-5	hSpCas9	negative selection	424771
694999	695022	11	-	26472758	K562	viability	GCAGCTGGGCCTGGCTGAGGCGG	EPS8L2	ENSG00000177106	-2.8168284611600938	[408]	[48]	-8	hSpCas9	negative selection	615882
694900	694923	11	-	26472758	K562	viability	GAGCAGGGACGAGGACTCGGAGG	EPS8L2	ENSG00000177106	0.4668111490028948	[53]	[62]	3	hSpCas9	negative selection	615884
694882	694905	11	-	26472758	K562	viability	GGAGGAGGACGCAGACTCGGAGG	EPS8L2	ENSG00000177106	-0.44307819023545936	[429]	[266]	-3	hSpCas9	negative selection	615885
694834	694857	11	-	26472758	K562	viability	GGCAGTGGCGGTGATGGCGGCGG	EPS8L2	ENSG00000177106	-2.662471867942072	[14]	[1]	-8	hSpCas9	negative selection	615887
694813	694836	11	-	26472758	K562	viability	GGAGCCCGGGCACATGGACATGG	EPS8L2	ENSG00000177106	0.2929172453576368	[233]	[241]	2	hSpCas9	negative selection	615888
694751	694774	11	+	26472758	K562	viability	GCACTTGCCTGCGAAGGCTGCGG	EPS8L2	ENSG00000177106	-0.2237856401276598	[432]	[312]	-1	hSpCas9	negative selection	615889
705936	705959	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCCCTAGAGCTGGGGCGCTGG	EPS8L2	ENSG00000177106	-0.2214845933930394	[21,35]	[1,7]	-1	dCas9-VP64	positive selection	2455081
705978	706001	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGTCCTCCCCAACACCCGCCTGG	EPS8L2	ENSG00000177106	1.500767521039994	[164,75]	[99,46]	5	dCas9-VP64	positive selection	2455082
705960	705983	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCCGCGGAGGGGCACACCAGG	EPS8L2	ENSG00000177106	-0.18468200222982045	[84,9]	[13,1]	0	dCas9-VP64	positive selection	2455083
705936	705959	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCCCTAGAGCTGGGGCGCTGG	EPS8L2	ENSG00000177106	-0.29767347656290977	[120,42]	[24,17]	-3	dCas9-VP64	positive selection	2550336
705978	706001	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGTCCTCCCCAACACCCGCCTGG	EPS8L2	ENSG00000177106	2.2207646256066753	[86,132]	[94,235]	8	dCas9-VP64	positive selection	2550337
705960	705983	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCCGCGGAGGGGCACACCAGG	EPS8L2	ENSG00000177106	0.12430198029127415	[30,38]	[13,9]	1	dCas9-VP64	positive selection	2550338
694550	694573	11	+	27661255	K562	viability	GGCAGGTGTGCAGGGCGGGTGGG	EPS8L2	ENSG00000177106	-0.19405013419392736	[769,710]	[560,480]	-6	dCas9-KRAB	negative selection	5474533
695013	695036	11	-	27661255	K562	viability	GACTCGGCGGCAAAGCAGCTGGG	EPS8L2	ENSG00000177106	-0.02474869838636687	[983,837]	[772,669]	-1	dCas9-KRAB	negative selection	5474534
695041	695064	11	-	27661255	K562	viability	GCTCGGCGGAGTCCGGATGGAGG	EPS8L2	ENSG00000177106	-0.0959330358951922	[228,330]	[188,223]	-4	dCas9-KRAB	negative selection	5474535
695055	695078	11	-	27661255	K562	viability	GCGCCTTCGGGAAGGCTCGGCGG	EPS8L2	ENSG00000177106	0.20578470396144954	[128,237]	[190,146]	7	dCas9-KRAB	negative selection	5474536
706223	706246	11	+	27661255	K562	viability	GCGCGAACAGACGGACGCACCGG	EPS8L2	ENSG00000177106	0.14808385164720494	[1113,1199]	[1174,892]	5	dCas9-KRAB	negative selection	5477650
706629	706652	11	+	27661255	K562	viability	GGAGAGCGCTGGTGGTAGGGAGG	EPS8L2	ENSG00000177106	0.09300029496296291	[414,419]	[407,310]	3	dCas9-KRAB	negative selection	5477651