Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2065
  • Symbol: ERBB3
  • Description: erb-b2 receptor tyrosine kinase 3
DataSource: http://genomecrispr.dkfz.de/#!/results/ERBB3

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
56085076 56085099 12 + 26472758 Jiyoye viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.2627854721706987 [146] [132] 2 hSpCas9 negative selection 51335
56085144 56085167 12 - 26472758 Jiyoye viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 1.599820459448269 [27] [63] 8 hSpCas9 negative selection 51336
56080361 56080384 12 + 26472758 Jiyoye viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.717515502118024 [49] [61] 5 hSpCas9 negative selection 51337
56083892 56083915 12 - 26472758 Jiyoye viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 6.337912719068759 [0] [60] 9 hSpCas9 negative selection 51338
56083821 56083844 12 + 26472758 Jiyoye viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.3080951415610137 [109] [66] -2 hSpCas9 negative selection 51339
56085051 56085074 12 + 26472758 Jiyoye viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 1.0833869445929831 [96] [154] 7 hSpCas9 negative selection 51340
56080309 56080332 12 + 26472758 Jiyoye viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.22085584110716877 [169] [109] -1 hSpCas9 negative selection 51341
56083784 56083807 12 - 26472758 Jiyoye viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.7717947595394459 [239] [105] -5 hSpCas9 negative selection 51342
56085021 56085044 12 - 26472758 Jiyoye viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 -0.2831401193615113 [70] [43] -2 hSpCas9 negative selection 51343
56085134 56085157 12 - 26472758 Jiyoye viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.717515502118024 [49] [61] 5 hSpCas9 negative selection 51344
56085076 56085099 12 + 26472758 KBM7 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.1929690126731854 [567,487] [292,273] 2 hSpCas9 negative selection 242453
56085144 56085167 12 - 26472758 KBM7 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 0.5571154895449313 [186,231] [208,91] 6 hSpCas9 negative selection 242454
56080361 56080384 12 + 26472758 KBM7 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.11558626812971018 [217,99] [71,61] -1 hSpCas9 negative selection 242455
56083892 56083915 12 - 26472758 KBM7 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -2.715547100263503 [59,91] [3,6] -9 hSpCas9 negative selection 242456
56083821 56083844 12 + 26472758 KBM7 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.4431140920450199 [469,299] [255,228] 5 hSpCas9 negative selection 242457
56085051 56085074 12 + 26472758 KBM7 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.6053821394469435 [509,284] [286,268] 6 hSpCas9 negative selection 242458
56080309 56080332 12 + 26472758 KBM7 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.4554539401753801 [660,713] [566,339] 5 hSpCas9 negative selection 242459
56083784 56083807 12 - 26472758 KBM7 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.37904791312118535 [675,909] [530,461] 4 hSpCas9 negative selection 242460
56085021 56085044 12 - 26472758 KBM7 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.665785041634604 [241,89] [153,86] 7 hSpCas9 negative selection 242461
56085134 56085157 12 - 26472758 KBM7 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.06136053678819453 [320,227] [66,191] 0 hSpCas9 negative selection 242462
56085076 56085099 12 + 26472758 Raji viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 -0.038293919822035505 [176] [39] 0 hSpCas9 negative selection 433571
56085144 56085167 12 - 26472758 Raji viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 0.5101427048740066 [117] [38] 5 hSpCas9 negative selection 433572
56080361 56080384 12 + 26472758 Raji viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.780141735367988 [110] [14] -5 hSpCas9 negative selection 433573
56083892 56083915 12 - 26472758 Raji viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.43995887446047033 [53] [16] 4 hSpCas9 negative selection 433574
56083821 56083844 12 + 26472758 Raji viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.032167817025194 [140] [31] 0 hSpCas9 negative selection 433575
56085051 56085074 12 + 26472758 Raji viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.3607653003648067 [248] [44] -3 hSpCas9 negative selection 433576
56080309 56080332 12 + 26472758 Raji viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.6646010456118514 [279] [102] 6 hSpCas9 negative selection 433577
56083784 56083807 12 - 26472758 Raji viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.25707646813144847 [374] [103] 2 hSpCas9 negative selection 433578
56085021 56085044 12 - 26472758 Raji viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.506990994082837 [46] [30] 9 hSpCas9 negative selection 433579
56085134 56085157 12 - 26472758 Raji viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -0.13723883334631415 [108] [22] -1 hSpCas9 negative selection 433580
56085076 56085099 12 + 26472758 K562 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 -0.10293196410082225 [457] [359] 0 hSpCas9 negative selection 624689
56085144 56085167 12 - 26472758 K562 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 0.11115219680298272 [135] [123] 0 hSpCas9 negative selection 624690
56080361 56080384 12 + 26472758 K562 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.9900465259705762 [159] [33] -7 hSpCas9 negative selection 624691
56083892 56083915 12 - 26472758 K562 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -0.4126935588105449 [81] [51] -3 hSpCas9 negative selection 624692
56083821 56083844 12 + 26472758 K562 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.22870513269812154 [396] [285] -1 hSpCas9 negative selection 624693
56085051 56085074 12 + 26472758 K562 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.7869454432428881 [371] [181] -5 hSpCas9 negative selection 624694
56080309 56080332 12 + 26472758 K562 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.3684898352243756 [411] [448] 3 hSpCas9 negative selection 624695
56083784 56083807 12 - 26472758 K562 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.06713795937623035 [466] [412] 0 hSpCas9 negative selection 624696
56085021 56085044 12 - 26472758 K562 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.5422550160429 [156] [192] 4 hSpCas9 negative selection 624697
56085134 56085157 12 - 26472758 K562 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -1.2223623467063953 [245] [88] -6 hSpCas9 negative selection 624698
56080361 56080384 12 + 26627737 DLD1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.10553392992281918 [323] [83,157,89] 1 hSpCas9 negative selection 784691
56083811 56083834 12 + 26627737 DLD1 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.5136634036146295 [1030] [389,372,592] 5 hSpCas9 negative selection 784692
56085059 56085082 12 + 26627737 DLD1 viability CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.9510219768225275 [1072] [226,134,158] -7 hSpCas9 negative selection 784693
56087580 56087603 12 - 26627737 DLD1 viability CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.14584787491827078 [1029] [275,348,255] -1 hSpCas9 negative selection 784694
56087860 56087883 12 + 26627737 DLD1 viability TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.015390771025478287 [476] [105,94,226] 0 hSpCas9 negative selection 784695
56088022 56088045 12 - 26627737 DLD1 viability ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.48513403293015844 [245] [18,48,90] -5 hSpCas9 negative selection 784696
56080361 56080384 12 + 26627737 GBM cells viability after 5 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.7884958948062881 [123] [43,32] -8 hSpCas9 negative selection 867006
56083811 56083834 12 + 26627737 GBM cells viability after 5 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5034125726436043 [677] [273,238] -7 hSpCas9 negative selection 867007
56085059 56085082 12 + 26627737 GBM cells viability after 5 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.6962443929413591 [425] [103,177] -8 hSpCas9 negative selection 867008
56087580 56087603 12 - 26627737 GBM cells viability after 5 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.9428240411975819 [551] [149,157] -9 hSpCas9 negative selection 867009
56087860 56087883 12 + 26627737 GBM cells viability after 5 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.8778094285182554 [232] [78,56] -8 hSpCas9 negative selection 867010
56088022 56088045 12 - 26627737 GBM cells viability after 5 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.1847440541612242 [70] [21,44] -3 hSpCas9 negative selection 867011
56080361 56080384 12 + 26627737 GBM cells viability after 13 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.0717617232708663 [123] [47,18] -8 hSpCas9 negative selection 949321
56083811 56083834 12 + 26627737 GBM cells viability after 13 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.15714016988891477 [677] [466,363] 2 hSpCas9 negative selection 949322
56085059 56085082 12 + 26627737 GBM cells viability after 13 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -1.279850549362112 [425] [135,61] -8 hSpCas9 negative selection 949323
56087580 56087603 12 - 26627737 GBM cells viability after 13 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.7572583791430563 [551] [217,143] -7 hSpCas9 negative selection 949324
56087860 56087883 12 + 26627737 GBM cells viability after 13 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.020463097174089645 [232] [165,90] 0 hSpCas9 negative selection 949325
56088022 56088045 12 - 26627737 GBM cells viability after 13 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 0.9295726971838176 [70] [63,80] 9 hSpCas9 negative selection 949326
56080361 56080384 12 + 26627737 GBM cells viability after 21 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.410365375788754 [123] [28,21] -8 hSpCas9 negative selection 1031636
56083811 56083834 12 + 26627737 GBM cells viability after 21 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.38588444955682455 [677] [532,433] 4 hSpCas9 negative selection 1031637
56085059 56085082 12 + 26627737 GBM cells viability after 21 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -1.0995888184467113 [425] [107,107] -7 hSpCas9 negative selection 1031638
56087580 56087603 12 - 26627737 GBM cells viability after 21 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -1.6898219708481501 [551] [93,91] -8 hSpCas9 negative selection 1031639
56087860 56087883 12 + 26627737 GBM cells viability after 21 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.4633559889427179 [232] [107,76] -4 hSpCas9 negative selection 1031640
56088022 56088045 12 - 26627737 GBM cells viability after 21 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 1.9205303105675362 [70] [168,124] 9 hSpCas9 negative selection 1031641
56080361 56080384 12 + 26627737 RPE1 viability after 9 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.3411449481465334 [286] [66,75] -2 hSpCas9 negative selection 1113951
56083811 56083834 12 + 26627737 RPE1 viability after 9 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.12512452334166446 [2034] [543,635] -1 hSpCas9 negative selection 1113952
56085059 56085082 12 + 26627737 RPE1 viability after 9 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -1.6198093473746016 [627] [49,81] -8 hSpCas9 negative selection 1113953
56087580 56087603 12 - 26627737 RPE1 viability after 9 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.736129954679118 [358] [229,131] 5 hSpCas9 negative selection 1113954
56087860 56087883 12 + 26627737 RPE1 viability after 9 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.17409607383024517 [367] [184,58] 1 hSpCas9 negative selection 1113955
56088022 56088045 12 - 26627737 RPE1 viability after 9 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.6343337144232273 [552] [97,128] -4 hSpCas9 negative selection 1113956
56080361 56080384 12 + 26627737 RPE1 viability after 12 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.20462033307044858 [286] [49,129] 1 hSpCas9 negative selection 1196266
56083811 56083834 12 + 26627737 RPE1 viability after 12 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.1480042220091511 [2034] [524,459] -1 hSpCas9 negative selection 1196267
56085059 56085082 12 + 26627737 RPE1 viability after 12 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.11132220901595799 [627] [241,118] 0 hSpCas9 negative selection 1196268
56087580 56087603 12 - 26627737 RPE1 viability after 12 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 1.3946823131021313 [358] [222,285] 7 hSpCas9 negative selection 1196269
56087860 56087883 12 + 26627737 RPE1 viability after 12 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.5845072592099072 [367] [139,156] 4 hSpCas9 negative selection 1196270
56088022 56088045 12 - 26627737 RPE1 viability after 12 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.8192759303825354 [552] [107,58] -5 hSpCas9 negative selection 1196271
56080361 56080384 12 + 26627737 RPE1 viability after 15 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.4524335562794841 [286] [105,115] 3 hSpCas9 negative selection 1278581
56083811 56083834 12 + 26627737 RPE1 viability after 15 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.4005293990338168 [2034] [851,670] 2 hSpCas9 negative selection 1278582
56085059 56085082 12 + 26627737 RPE1 viability after 15 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.5226557791187786 [627] [170,77] -3 hSpCas9 negative selection 1278583
56087580 56087603 12 - 26627737 RPE1 viability after 15 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.7910761261660413 [358] [134,214] 5 hSpCas9 negative selection 1278584
56087860 56087883 12 + 26627737 RPE1 viability after 15 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 1.1087440134363111 [367] [308,142] 6 hSpCas9 negative selection 1278585
56088022 56088045 12 - 26627737 RPE1 viability after 15 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.4107324617352919 [552] [67,49] -7 hSpCas9 negative selection 1278586
56080361 56080384 12 + 26627737 RPE1 viability after 18 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.9581765546504457 [286] [76,228] 6 hSpCas9 negative selection 1360896
56083811 56083834 12 + 26627737 RPE1 viability after 18 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.1296553610715987 [2034] [551,652] 0 hSpCas9 negative selection 1360897
56085059 56085082 12 + 26627737 RPE1 viability after 18 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.22526718334835227 [627] [288,100] 1 hSpCas9 negative selection 1360898
56087580 56087603 12 - 26627737 RPE1 viability after 18 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 1.1311670699661587 [358] [261,158] 6 hSpCas9 negative selection 1360899
56087860 56087883 12 + 26627737 RPE1 viability after 18 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.21735207113682353 [367] [157,69] 1 hSpCas9 negative selection 1360900
56088022 56088045 12 - 26627737 RPE1 viability after 18 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.1437910618092417 [552] [24,112] -6 hSpCas9 negative selection 1360901
56080361 56080384 12 + 26627737 HeLa viability after 8 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.5927801600668482 [535] [286,79,127] -5 hSpCas9 negative selection 1443211
56083811 56083834 12 + 26627737 HeLa viability after 8 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.3689174048473123 [1413] [296,212,218] -8 hSpCas9 negative selection 1443212
56085059 56085082 12 + 26627737 HeLa viability after 8 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.7210178895777893 [513] [159,80,168] -6 hSpCas9 negative selection 1443213
56087580 56087603 12 - 26627737 HeLa viability after 8 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.04531612534124607 [615] [337,164,335] 0 hSpCas9 negative selection 1443214
56087860 56087883 12 + 26627737 HeLa viability after 8 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.6722368903810174 [326] [132,121,26] -6 hSpCas9 negative selection 1443215
56088022 56088045 12 - 26627737 HeLa viability after 8 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.2997481731609122 [356] [11,116,49] -8 hSpCas9 negative selection 1443216
56080361 56080384 12 + 26627737 HeLa viability after 12 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.014568419898909 [535] [40,108,176] -7 hSpCas9 negative selection 1525526
56083811 56083834 12 + 26627737 HeLa viability after 12 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6706685624063469 [1413] [585,363,157] -6 hSpCas9 negative selection 1525527
56085059 56085082 12 + 26627737 HeLa viability after 12 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.5273704460575028 [513] [137,164,136] -5 hSpCas9 negative selection 1525528
56087580 56087603 12 - 26627737 HeLa viability after 12 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.13870055972195017 [615] [396,196,258] 1 hSpCas9 negative selection 1525529
56087860 56087883 12 + 26627737 HeLa viability after 12 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.1986169479629027 [326] [232,66,61] -2 hSpCas9 negative selection 1525530
56088022 56088045 12 - 26627737 HeLa viability after 12 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.9773173807943043 [356] [60,9,44] -9 hSpCas9 negative selection 1525531
56080361 56080384 12 + 26627737 HeLa viability after 15 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.3849661175325345 [535] [52,102,95] -8 hSpCas9 negative selection 1607841
56083811 56083834 12 + 26627737 HeLa viability after 15 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.9887494124637183 [1413] [225,258,393] -7 hSpCas9 negative selection 1607842
56085059 56085082 12 + 26627737 HeLa viability after 15 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.08374079339988683 [513] [187,348,120] 0 hSpCas9 negative selection 1607843
56087580 56087603 12 - 26627737 HeLa viability after 15 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.022394319348465253 [615] [373,215,140] 0 hSpCas9 negative selection 1607844
56087860 56087883 12 + 26627737 HeLa viability after 15 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.3121946834452559 [326] [185,247,52] 2 hSpCas9 negative selection 1607845
56088022 56088045 12 - 26627737 HeLa viability after 15 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.7732596831446568 [356] [61,76,118] -6 hSpCas9 negative selection 1607846
56080361 56080384 12 + 26627737 HeLa viability after 18 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.3973635396001995 [535] [35,82,95] -8 hSpCas9 negative selection 1690156
56083811 56083834 12 + 26627737 HeLa viability after 18 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.9639211718198566 [1413] [156,219,393] -7 hSpCas9 negative selection 1690157
56085059 56085082 12 + 26627737 HeLa viability after 18 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.06919680711073656 [513] [116,294,120] 0 hSpCas9 negative selection 1690158
56087580 56087603 12 - 26627737 HeLa viability after 18 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.004317119018290683 [615] [258,179,140] 0 hSpCas9 negative selection 1690159
56087860 56087883 12 + 26627737 HeLa viability after 18 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.2864776234062435 [326] [120,202,52] 2 hSpCas9 negative selection 1690160
56088022 56088045 12 - 26627737 HeLa viability after 18 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.7388405989901357 [356] [42,66,118] -6 hSpCas9 negative selection 1690161
56080361 56080384 12 + 26627737 HCT116 viability after 6 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 2.0656663744532477 [310] [301,150] 8 hSpCas9 negative selection 1772471
56083811 56083834 12 + 26627737 HCT116 viability after 6 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 1.074003256304833 [1972] [846,545] 6 hSpCas9 negative selection 1772472
56085059 56085082 12 + 26627737 HCT116 viability after 6 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.26877119439806907 [1012] [488,27] 1 hSpCas9 negative selection 1772473
56087580 56087603 12 - 26627737 HCT116 viability after 6 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.6099790908428959 [802] [182,197] 3 hSpCas9 negative selection 1772474
56087860 56087883 12 + 26627737 HCT116 viability after 6 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -1.2710126604269518 [540] [51,25] -6 hSpCas9 negative selection 1772475
56088022 56088045 12 - 26627737 HCT116 viability after 6 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 0.3854876718735668 [422] [82,88] 2 hSpCas9 negative selection 1772476
56080361 56080384 12 + 26627737 HCT116 viability after 8 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.7117267764724629 [317] [103,33,181] -7 hSpCas9 negative selection 1854786
56083811 56083834 12 + 26627737 HCT116 viability after 8 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.8092896334413827 [1023] [282,335,345] -7 hSpCas9 negative selection 1854787
56085059 56085082 12 + 26627737 HCT116 viability after 8 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.4136458283160801 [362] [148,112,187] -5 hSpCas9 negative selection 1854788
56087580 56087603 12 - 26627737 HCT116 viability after 8 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.07747110065411533 [547] [350,332,272] 0 hSpCas9 negative selection 1854789
56087860 56087883 12 + 26627737 HCT116 viability after 8 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.2069109789748822 [310] [132,151,159] -2 hSpCas9 negative selection 1854790
56088022 56088045 12 - 26627737 HCT116 viability after 8 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 1.8551330453750712 [38] [109,60,62] 9 hSpCas9 negative selection 1854791
56080361 56080384 12 + 26627737 HCT116 viability after 9 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 1.71048678719049 [310] [230,303] 9 hSpCas9 negative selection 1937101
56083811 56083834 12 + 26627737 HCT116 viability after 9 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.06212601021679398 [1972] [444,632] 0 hSpCas9 negative selection 1937102
56085059 56085082 12 + 26627737 HCT116 viability after 9 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.47737351988738963 [1012] [367,56] -3 hSpCas9 negative selection 1937103
56087580 56087603 12 - 26627737 HCT116 viability after 9 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.9138164251788374 [802] [327,463] 6 hSpCas9 negative selection 1937104
56087860 56087883 12 + 26627737 HCT116 viability after 9 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 0.2890662197405254 [540] [247,119] 2 hSpCas9 negative selection 1937105
56088022 56088045 12 - 26627737 HCT116 viability after 9 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.1583558205379765 [422] [82,24] -7 hSpCas9 negative selection 1937106
56080361 56080384 12 + 26627737 HCT116 viability after 12 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.570173651970824 [317] [210,69,46] -6 hSpCas9 negative selection 2019416
56083811 56083834 12 + 26627737 HCT116 viability after 12 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6709689329285877 [1023] [277,285,453] -6 hSpCas9 negative selection 2019417
56085059 56085082 12 + 26627737 HCT116 viability after 12 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.21790323077246712 [362] [118,162,213] -2 hSpCas9 negative selection 2019418
56087580 56087603 12 - 26627737 HCT116 viability after 12 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.07101196471231708 [547] [222,403,289] 0 hSpCas9 negative selection 2019419
56087860 56087883 12 + 26627737 HCT116 viability after 12 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.13241921389334793 [310] [124,89,232] -1 hSpCas9 negative selection 2019420
56088022 56088045 12 - 26627737 HCT116 viability after 12 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 1.7775780501279017 [38] [77,64,66] 9 hSpCas9 negative selection 2019421
56080361 56080384 12 + 26627737 HCT116 viability after 15 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.1961875801875303 [317] [307,146,184] 2 hSpCas9 negative selection 2101731
56083811 56083834 12 + 26627737 HCT116 viability after 15 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.4613006566310085 [1023] [473,375,436] -5 hSpCas9 negative selection 2101732
56085059 56085082 12 + 26627737 HCT116 viability after 15 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.5498898600326245 [362] [125,139,158] -5 hSpCas9 negative selection 2101733
56087580 56087603 12 - 26627737 HCT116 viability after 15 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.11775046159285629 [547] [393,309,326] 1 hSpCas9 negative selection 2101734
56087860 56087883 12 + 26627737 HCT116 viability after 15 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.31467472671187774 [310] [63,202,153] -3 hSpCas9 negative selection 2101735
56088022 56088045 12 - 26627737 HCT116 viability after 15 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 1.816294346554831 [38] [40,109,80] 9 hSpCas9 negative selection 2101736
56080361 56080384 12 + 26627737 HCT116 viability after 18 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.15004912383479413 [317] [159,112,245] 1 hSpCas9 negative selection 2184046
56083811 56083834 12 + 26627737 HCT116 viability after 18 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.3259446076248034 [1023] [395,315,481] -3 hSpCas9 negative selection 2184047
56085059 56085082 12 + 26627737 HCT116 viability after 18 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.02209164929097429 [362] [211,237,75] 0 hSpCas9 negative selection 2184048
56087580 56087603 12 - 26627737 HCT116 viability after 18 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.1928518763674426 [547] [139,280,272] -2 hSpCas9 negative selection 2184049
56087860 56087883 12 + 26627737 HCT116 viability after 18 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.03941285345283445 [310] [71,175,190] 0 hSpCas9 negative selection 2184050
56088022 56088045 12 - 26627737 HCT116 viability after 18 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 1.883256708409236 [38] [70,48,90] 9 hSpCas9 negative selection 2184051
56080303 56080326 12 + 24336569 HL60 viability GAGGGCGAACGACGCTCTGCAGG ERBB3 ENSG00000065361 0.3161728218412494 [708] [1867] 3 hSpCas9 negative selection 2263102
56080309 56080332 12 + 24336569 HL60 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.27982907890496256 [1046] [1824] -2 hSpCas9 negative selection 2263103
56080357 56080380 12 + 24336569 HL60 viability CTCCGAGGTGGGCAACTCTCAGG ERBB3 ENSG00000065361 2.2583859022557284 [103] [1052] 9 hSpCas9 negative selection 2263104
56083738 56083761 12 + 24336569 HL60 viability CTGCTTTGAACAGTGTGTCCTGG ERBB3 ENSG00000065361 1.7258908214287076 [166] [1168] 9 hSpCas9 negative selection 2263105
56083750 56083773 12 + 24336569 HL60 viability GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 0.470413766772996 [543] [1594] 4 hSpCas9 negative selection 2263106
56083756 56083779 12 - 24336569 HL60 viability CTCAGGCCATTCAGAGTCCCAGG ERBB3 ENSG00000065361 7.807279148269362 [0] [473] 9 hSpCas9 negative selection 2263107
56083765 56083788 12 + 24336569 HL60 viability CTGAATGGCCTGAGTGTGACCGG ERBB3 ENSG00000065361 1.0101125017232435 [514] [2194] 7 hSpCas9 negative selection 2263108
56083773 56083796 12 - 24336569 HL60 viability CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 1.523200314534808 [399] [2432] 8 hSpCas9 negative selection 2263109
56083784 56083807 12 - 24336569 HL60 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.26314711600654284 [731] [1858] 2 hSpCas9 negative selection 2263110
56083800 56083823 12 - 24336569 HL60 viability GCTTGTACAGTGTCTGGTATTGG ERBB3 ENSG00000065361 1.0676080387284175 [270] [1201] 7 hSpCas9 negative selection 2263111
56080303 56080326 12 + 24336569 KBM7 viability GAGGGCGAACGACGCTCTGCAGG ERBB3 ENSG00000065361 -0.24229170010387635 [702] [1620] -2 hSpCas9 negative selection 2330279
56080309 56080332 12 + 24336569 KBM7 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.8956478133667907 [510] [2592] 7 hSpCas9 negative selection 2330280
56080357 56080380 12 + 24336569 KBM7 viability CTCCGAGGTGGGCAACTCTCAGG ERBB3 ENSG00000065361 0.22463018927508177 [261] [834] 2 hSpCas9 negative selection 2330281
56083738 56083761 12 + 24336569 KBM7 viability CTGCTTTGAACAGTGTGTCCTGG ERBB3 ENSG00000065361 0.10802939142501122 [330] [972] 1 hSpCas9 negative selection 2330282
56083750 56083773 12 + 24336569 KBM7 viability GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 -0.6468429522298265 [592] [1032] -5 hSpCas9 negative selection 2330283
56083756 56083779 12 - 24336569 KBM7 viability CTCAGGCCATTCAGAGTCCCAGG ERBB3 ENSG00000065361 0.2153858161735469 [59] [189] 2 hSpCas9 negative selection 2330284
56083765 56083788 12 + 24336569 KBM7 viability CTGAATGGCCTGAGTGTGACCGG ERBB3 ENSG00000065361 1.3539647074178747 [461] [3220] 9 hSpCas9 negative selection 2330285
56083773 56083796 12 - 24336569 KBM7 viability CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.2030444659717784 [586] [1842] 2 hSpCas9 negative selection 2330286
56083784 56083807 12 - 24336569 KBM7 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.6900489110105867 [807] [1365] -5 hSpCas9 negative selection 2330287
56083800 56083823 12 - 24336569 KBM7 viability GCTTGTACAGTGTCTGGTATTGG ERBB3 ENSG00000065361 -0.12791297049309108 [382] [955] -1 hSpCas9 negative selection 2330288
56079958 56079981 12 - 25494202 A375 resistance to PLX-4720 (puromycin) CCCGCGGTCCCGCAACTTGGCGG ERBB3 ENSG00000065361 0.2698097654990519 [263,200] [11,114] 1 dCas9-VP64 positive selection 2387939
56080006 56080029 12 - 25494202 A375 resistance to PLX-4720 (puromycin) GAGTAGGGATTGCGGAGCCTCGG ERBB3 ENSG00000065361 -0.8113976516722801 [199,208] [18,31] -4 dCas9-VP64 positive selection 2387940
56079918 56079941 12 - 25494202 A375 resistance to PLX-4720 (puromycin) GCTCACCCTAATTTTTCTGCAGG ERBB3 ENSG00000065361 -1.640095077237501 [439,576] [27,43] -8 dCas9-VP64 positive selection 2387941
56089175 56089198 12 - 25494202 A375 resistance to PLX-4720 (puromycin) CACGCCACTGCACTCCAGCCTAG ERBB3 ENSG00000065361 -0.23120917697478569 [21,115] [6,17] -1 dCas9-VP64 positive selection 2389298
56079888 56079911 12 + 25494202 A375 resistance to PLX-4720 (puromycin) TCGGAATCTCGACCTCCCCTTGG ERBB3 ENSG00000065361 0.12850977916637296 [18,37] [7,4] 0 dCas9-VP64 positive selection 2429120
56079862 56079885 12 + 25494202 A375 resistance to PLX-4720 (puromycin) TTACCCTTCCCTGGATCTGGGGG ERBB3 ENSG00000065361 -0.3639644473025201 [40,44] [8,4] -2 dCas9-VP64 positive selection 2429121
56100389 56100412 12 + 25494202 A375 resistance to PLX-4720 (puromycin) CCCAGCACTTTGGGAGGCCAGAG ERBB3 ENSG00000065361 -3.2327828351083694 [281,50] [1,4] -9 dCas9-VP64 positive selection 2431331
56094806 56094829 12 - 25494202 A375 resistance to PLX-4720 (puromycin) CAGGCATGCGCCACCACGCCGGG ERBB3 ENSG00000065361 0.7395023947734947 [14,26] [11,2] 3 dCas9-VP64 positive selection 2436168
56099049 56099072 12 - 25494202 A375 resistance to PLX-4720 (puromycin) CAGGAGAATCTCTTGAACCCGAG ERBB3 ENSG00000065361 0.7055876385115556 [3,484] [1,182] 3 dCas9-VP64 positive selection 2452104
56080089 56080112 12 - 25494202 A375 resistance to PLX-4720 (puromycin) GTGTGAGAGAGAGAGAGAGAGGG ERBB3 ENSG00000065361 3.246472249107505 [0,4] [1,12] 8 dCas9-VP64 positive selection 2458448
56079958 56079981 12 - 25494202 A375 resistance to PLX-4720 (zeocin) CCCGCGGTCCCGCAACTTGGCGG ERBB3 ENSG00000065361 0.2412700798252256 [192,25] [76,9] 2 dCas9-VP64 positive selection 2483194
56080006 56080029 12 - 25494202 A375 resistance to PLX-4720 (zeocin) GAGTAGGGATTGCGGAGCCTCGG ERBB3 ENSG00000065361 -0.7612077839120586 [192,305] [44,49] -7 dCas9-VP64 positive selection 2483195
56079918 56079941 12 - 25494202 A375 resistance to PLX-4720 (zeocin) GCTCACCCTAATTTTTCTGCAGG ERBB3 ENSG00000065361 -0.4779075926911096 [450,452] [163,50] -5 dCas9-VP64 positive selection 2483196
56089175 56089198 12 - 25494202 A375 resistance to PLX-4720 (zeocin) CACGCCACTGCACTCCAGCCTAG ERBB3 ENSG00000065361 -0.7543799798568478 [117,158] [37,14] -7 dCas9-VP64 positive selection 2484553
56079888 56079911 12 + 25494202 A375 resistance to PLX-4720 (zeocin) TCGGAATCTCGACCTCCCCTTGG ERBB3 ENSG00000065361 0.6929537605637239 [192,97] [83,70] 5 dCas9-VP64 positive selection 2524375
56079862 56079885 12 + 25494202 A375 resistance to PLX-4720 (zeocin) TTACCCTTCCCTGGATCTGGGGG ERBB3 ENSG00000065361 0.40642705023875 [78,221] [50,76] 3 dCas9-VP64 positive selection 2524376
56100389 56100412 12 + 25494202 A375 resistance to PLX-4720 (zeocin) CCCAGCACTTTGGGAGGCCAGAG ERBB3 ENSG00000065361 0.5850522226976638 [88,64] [38,35] 4 dCas9-VP64 positive selection 2526586
56094806 56094829 12 - 25494202 A375 resistance to PLX-4720 (zeocin) CAGGCATGCGCCACCACGCCGGG ERBB3 ENSG00000065361 0.19409034858978108 [82,214] [36,71] 1 dCas9-VP64 positive selection 2531423
56099049 56099072 12 - 25494202 A375 resistance to PLX-4720 (zeocin) CAGGAGAATCTCTTGAACCCGAG ERBB3 ENSG00000065361 -0.4319067453035411 [83,67] [14,20] -4 dCas9-VP64 positive selection 2547359
56080089 56080112 12 - 25494202 A375 resistance to PLX-4720 (zeocin) GTGTGAGAGAGAGAGAGAGAGGG ERBB3 ENSG00000065361 2.8702956375825326 [127,55] [142,294] 9 dCas9-VP64 positive selection 2553703
56083738 56083761 12 + 27013184 SW480 treatment with recombinant TRAIL CTGCTTTGAACAGTGTGTCCTGG ERBB3 ENSG00000065361 0.13708600306695246 [254,295] [81,197] 0 hSpCas9 positive selection 2954728
56083739 56083762 12 + 27013184 SW480 treatment with recombinant TRAIL TGCTTTGAACAGTGTGTCCTGGG ERBB3 ENSG00000065361 -1.0163805959462056 [294,337] [95,25] -4 hSpCas9 positive selection 2954729
56080285 56080308 12 + 27013184 SW480 treatment with recombinant TRAIL CACCCTCTGCGGAGTCATGAGGG ERBB3 ENSG00000065361 0.2821239849543591 [398,688] [307,236] 1 hSpCas9 positive selection 2954730
56080309 56080332 12 + 27013184 SW480 treatment with recombinant TRAIL GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.9447576965058933 [45,94] [4,29] -4 hSpCas9 positive selection 2954731
56080310 56080333 12 + 27013184 SW480 treatment with recombinant TRAIL AACGACGCTCTGCAGGTGCTGGG ERBB3 ENSG00000065361 1.8778870805494638 [116,113] [137,247] 8 hSpCas9 positive selection 2954732
56080357 56080380 12 + 27013184 SW480 treatment with recombinant TRAIL CTCCGAGGTGGGCAACTCTCAGG ERBB3 ENSG00000065361 -3.4914327346039125 [127,498] [17,1] -9 hSpCas9 positive selection 2954733
56080361 56080384 12 + 27013184 SW480 treatment with recombinant TRAIL GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.3555949017288271 [264,466] [72,41] -6 hSpCas9 positive selection 2954734
56080368 56080391 12 + 27013184 SW480 treatment with recombinant TRAIL GCAACTCTCAGGCAGGTAAGTGG ERBB3 ENSG00000065361 -0.3979260395686837 [168,218] [42,90] -2 hSpCas9 positive selection 2954735
56083750 56083773 12 + 27013184 SW480 treatment with recombinant TRAIL GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 -0.09704789592653418 [1038,1362] [408,577] 0 hSpCas9 positive selection 2954736
56083734 56083757 12 - 27013184 SW480 treatment with recombinant TRAIL GACACACTGTTCAAAGCAGAGGG ERBB3 ENSG00000065361 -1.2814751381899159 [13,7] [1,1] -5 hSpCas9 positive selection 2954737
56083765 56083788 12 + 27013184 SW480 treatment with recombinant TRAIL CTGAATGGCCTGAGTGTGACCGG ERBB3 ENSG00000065361 -1.5909292880634518 [284,409] [29,75] -6 hSpCas9 positive selection 2954738
56083773 56083796 12 - 27013184 SW480 treatment with recombinant TRAIL CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.37966171334099674 [824,689] [374,504] 2 hSpCas9 positive selection 2954739
56083784 56083807 12 - 27013184 SW480 treatment with recombinant TRAIL GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.1269185279056561 [335,193] [145,101] 0 hSpCas9 positive selection 2954740
56083800 56083823 12 - 27013184 SW480 treatment with recombinant TRAIL GCTTGTACAGTGTCTGGTATTGG ERBB3 ENSG00000065361 1.5079000169590506 [26,28] [51,8] 7 hSpCas9 positive selection 2954741
56083806 56083829 12 - 27013184 SW480 treatment with recombinant TRAIL CGTAGAGCTTGTACAGTGTCTGG ERBB3 ENSG00000065361 1.100550014394602 [265,99] [157,201] 5 hSpCas9 positive selection 2954742
56083854 56083877 12 - 27013184 SW480 treatment with recombinant TRAIL GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 1.1474996244677833 [763,794] [650,875] 5 hSpCas9 positive selection 2954743
56083892 56083915 12 - 27013184 SW480 treatment with recombinant TRAIL GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.7382029578025695 [80,137] [76,76] 3 hSpCas9 positive selection 2954744
56083896 56083919 12 - 27013184 SW480 treatment with recombinant TRAIL GGGTGGGCTCACTAACCTGCAGG ERBB3 ENSG00000065361 -0.4794258304988821 [141,132] [26,64] -2 hSpCas9 positive selection 2954745
56080280 56080303 12 - 27013184 SW480 treatment with recombinant TRAIL ATGACTCCGCAGAGGGTGAAGGG ERBB3 ENSG00000065361 -0.608374195156402 [326,220] [101,45] -3 hSpCas9 positive selection 2954746
56083811 56083834 12 + 27013184 SW480 treatment with recombinant TRAIL CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.23903552149471485 [17,44] [1,23] -1 hSpCas9 positive selection 2954747
56080281 56080304 12 - 27013184 SW480 treatment with recombinant TRAIL CATGACTCCGCAGAGGGTGAAGG ERBB3 ENSG00000065361 -1.9973689085906954 [104,85] [9,10] -7 hSpCas9 positive selection 2954748
56080287 56080310 12 - 27013184 SW480 treatment with recombinant TRAIL CGCCCTCATGACTCCGCAGAGGG ERBB3 ENSG00000065361 0.7266183907185527 [188,181] [116,154] 3 hSpCas9 positive selection 2954749
56080288 56080311 12 - 27013184 SW480 treatment with recombinant TRAIL TCGCCCTCATGACTCCGCAGAGG ERBB3 ENSG00000065361 2.518912601303359 [171,135] [272,543] 9 hSpCas9 positive selection 2954750
56080351 56080374 12 - 27013184 SW480 treatment with recombinant TRAIL AGTTGCCCACCTCGGAGCCCCGG ERBB3 ENSG00000065361 1.5295771417923867 [389,447] [245,906] 7 hSpCas9 positive selection 2954751
56080359 56080382 12 - 27013184 SW480 treatment with recombinant TRAIL TGCCTGAGAGTTGCCCACCTCGG ERBB3 ENSG00000065361 0.2799819481443394 [121,144] [16,143] 1 hSpCas9 positive selection 2954752
56083818 56083841 12 + 27013184 SW480 treatment with recombinant TRAIL CAAGCTCTACGAGAGGTGTGAGG ERBB3 ENSG00000065361 -0.391897225700396 [442,495] [54,293] -2 hSpCas9 positive selection 2954753
56083821 56083844 12 + 27013184 SW480 treatment with recombinant TRAIL GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -3.505418545603784 [407,410] [3,31] -9 hSpCas9 positive selection 2954754
56083851 56083874 12 + 27013184 SW480 treatment with recombinant TRAIL GAACCTTGAGATTGTGCTCACGG ERBB3 ENSG00000065361 -1.1918409515808819 [1012,1106] [210,182] -5 hSpCas9 positive selection 2954755
56083852 56083875 12 + 27013184 SW480 treatment with recombinant TRAIL AACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -3.154323698571206 [158,57] [2,8] -9 hSpCas9 positive selection 2954756
56080284 56080307 12 + 27013184 SW480 treatment with recombinant TRAIL TCACCCTCTGCGGAGTCATGAGG ERBB3 ENSG00000065361 -3.0600144583609907 [65,75] [1,5] -9 hSpCas9 positive selection 2954757
56085021 56085044 12 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.18693333652964875 [3,3] [2,3] 4 hSpCas9 positive selection 2986211
56083812 56083835 12 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.040140769822039624 [4,4] [4,3] 0 hSpCas9 positive selection 2986212
56083822 56083845 12 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.15423403411846454 [3,3] [3,1] -2 hSpCas9 positive selection 2986213
56083751 56083774 12 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 0.4966711342956947 [4,4] [5,6] 8 hSpCas9 positive selection 2986214
56085021 56085044 12 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 -0.017417682641393102 [3,3] [2,2] 0 hSpCas9 positive selection 3054069
56083812 56083835 12 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.8744695732340557 [4,4] [1,0] -9 hSpCas9 positive selection 3054070
56083822 56083845 12 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.3497968604647011 [3,3] [2,3] 6 hSpCas9 positive selection 3054071
56083751 56083774 12 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 0.30196115103044985 [4,4] [5,3] 5 hSpCas9 positive selection 3054072
56099725 56099748 - 24336571 A375 resistance to PLX after 7 days ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.2515894370182523 [8,6] [7,4] -7 hSpCas9 positive selection 3112379
56085084 56085107 - 24336571 A375 resistance to PLX after 7 days CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 0.04598450876464802 [10,11] [13,9] 1 hSpCas9 positive selection 3112380
56083811 56083834 + 24336571 A375 resistance to PLX after 7 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.1534846816226092 [5,4] [3,4] -5 hSpCas9 positive selection 3112382
56083773 56083796 - 24336571 A375 resistance to PLX after 7 days CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.7552030411055679 [14,10] [6,7] -9 hSpCas9 positive selection 3112383
56084992 56085015 + 24336571 A375 resistance to PLX after 7 days CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.443043767127278 [12,12] [9,8] -9 hSpCas9 positive selection 3112384
56099715 56099738 + 24336571 A375 resistance to PLX after 7 days CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.14580689935992996 [24,26] [27,29] 5 hSpCas9 positive selection 3112385
56095662 56095685 + 24336571 A375 resistance to PLX after 7 days TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 0.09755115458035113 [3,3] [3,3] 3 hSpCas9 positive selection 3112386
56095739 56095762 + 24336571 A375 resistance to PLX after 7 days TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.2470692697594572 [8,7] [5,6] -7 hSpCas9 positive selection 3112387
56099725 56099748 - 24336571 A375 resistance to PLX after 14 days ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.2422189117087059 [7,5] [2,3] 2 hSpCas9 positive selection 3170172
56085084 56085107 - 24336571 A375 resistance to PLX after 14 days CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 0.379859990543544 [13,10] [6,7] 3 hSpCas9 positive selection 3170173
56083811 56083834 + 24336571 A375 resistance to PLX after 14 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.8982943430306205 [5,3] [4,2] 7 hSpCas9 positive selection 3170175
56083773 56083796 - 24336571 A375 resistance to PLX after 14 days CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -1.1599411548923388 [12,11] [1,1] -9 hSpCas9 positive selection 3170176
56084992 56085015 + 24336571 A375 resistance to PLX after 14 days CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.731625878214534 [11,16] [3,3] -8 hSpCas9 positive selection 3170177
56099715 56099738 + 24336571 A375 resistance to PLX after 14 days CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 1.4561406929781653 [17,37] [29,41] 8 hSpCas9 positive selection 3170178
56095662 56095685 + 24336571 A375 resistance to PLX after 14 days TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 1.5475134797371024 [2,1] [3,2] 9 hSpCas9 positive selection 3170179
56095739 56095762 + 24336571 A375 resistance to PLX after 14 days TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.24213435658599675 [7,9] [2,2] -3 hSpCas9 positive selection 3170180
56099725 56099748 - 24336571 A375 viability after 7 days ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.3933679177794458 [10] [8,6] -5 hSpCas9 negative selection 3227965
56085084 56085107 - 24336571 A375 viability after 7 days CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 -0.04554219405228267 [12] [10,11] 0 hSpCas9 negative selection 3227966
56083811 56083834 + 24336571 A375 viability after 7 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.010308145839836413 [5] [5,4] 0 hSpCas9 negative selection 3227968
56083773 56083796 - 24336571 A375 viability after 7 days CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.2907445079066435 [16] [14,10] -4 hSpCas9 negative selection 3227969
56084992 56085015 + 24336571 A375 viability after 7 days CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 0.08502018347197977 [12] [12,12] 1 hSpCas9 negative selection 3227970
56099715 56099738 + 24336571 A375 viability after 7 days CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.6283957158563731 [17] [24,26] 8 hSpCas9 negative selection 3227971
56095662 56095685 + 24336571 A375 viability after 7 days TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 -0.8406075432939083 [7] [3,3] -8 hSpCas9 negative selection 3227972
56095739 56095762 + 24336571 A375 viability after 7 days TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 0.10473811031868074 [7] [8,7] 1 hSpCas9 negative selection 3227973
56099725 56099748 - 24336571 A375 viability after 14 days ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.6123198503548759 [10] [7,5] -6 hSpCas9 negative selection 3285758
56085084 56085107 - 24336571 A375 viability after 14 days CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 0.07796121160423335 [12] [13,10] 1 hSpCas9 negative selection 3285759
56083811 56083834 + 24336571 A375 viability after 14 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.09723660691991332 [5] [5,3] -1 hSpCas9 negative selection 3285761
56083773 56083796 - 24336571 A375 viability after 14 days CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.354611128030446 [16] [12,11] -4 hSpCas9 negative selection 3285762
56084992 56085015 + 24336571 A375 viability after 14 days CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 0.26673263420804494 [12] [11,16] 3 hSpCas9 negative selection 3285763
56099715 56099738 + 24336571 A375 viability after 14 days CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.7367344264277831 [17] [17,37] 8 hSpCas9 negative selection 3285764
56095662 56095685 + 24336571 A375 viability after 14 days TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 -1.5189024285476314 [7] [2,1] -9 hSpCas9 negative selection 3285765
56095739 56095762 + 24336571 A375 viability after 14 days TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 0.2067798527963975 [7] [7,9] 2 hSpCas9 negative selection 3285766
56083811 56083834 12 + 27383988 293T resistance to West Nile virus (flavivirus) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.9933589915802279 [53,99] [0,0] 4 hSpCas9 positive selection 3348248
56095739 56095762 12 + 27383988 293T resistance to West Nile virus (flavivirus) TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 3.468044748942005 [37,44] [0,4] 9 hSpCas9 positive selection 3348249
56083854 56083877 12 - 27383988 293T resistance to West Nile virus (flavivirus) GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.28004628794591846 [251,251] [0,2] 1 hSpCas9 positive selection 3348250
56101235 56101258 12 - 27383988 293T resistance to West Nile virus (flavivirus) TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 0.5568864933047428 [103,103] [0,0] 3 hSpCas9 positive selection 3367459
56099725 56099748 12 - 27383988 293T resistance to West Nile virus (flavivirus) ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.8771001087750909 [280,280] [0,0] -6 hSpCas9 positive selection 3367460
56099715 56099738 12 + 27383988 293T resistance to West Nile virus (flavivirus) CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 -0.2264895658184215 [178,178] [0,0] -1 hSpCas9 positive selection 3367461
56085021 56085044 12 - 26780180 HT29 viability (Avana library 4 designs) AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.817474666615274 [] [] 3 hSpCas9 negative selection 3423034
56083811 56083834 12 + 26780180 HT29 viability (Avana library 4 designs) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.915217118657557 [] [] 3 hSpCas9 negative selection 3423035
56083821 56083844 12 + 26780180 HT29 viability (Avana library 4 designs) GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 2.24927520606056 [] [] 7 hSpCas9 negative selection 3423036
56083750 56083773 12 + 26780180 HT29 viability (Avana library 4 designs) GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 0.361673573713529 [] [] 1 hSpCas9 negative selection 3423037
56083821 56083844 12 + 26780180 A375 viability (Avana lentiCRISPRv2) GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.90423763240424 [] [] 1 hSpCas9 negative selection 3503989
56083750 56083773 12 + 26780180 A375 viability (Avana lentiCRISPRv2) GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 3.50380944979138 [] [] 5 hSpCas9 negative selection 3503990
56085021 56085044 12 - 26780180 A375 viability (Avana lentiCRISPRv2) AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 2.11748728602114 [] [] 3 hSpCas9 negative selection 3503991
56083811 56083834 12 + 26780180 A375 viability (Avana lentiCRISPRv2) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.385044358396882 [] [] 0 hSpCas9 negative selection 3503992
56083784 56083807 12 - 26780180 A375 viability (Avana lentiCRISPRv2) GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -3.8744107312907 [] [] -4 hSpCas9 negative selection 3503993
56080285 56080308 12 + 26780180 A375 viability (Avana lentiCRISPRv2) CACCCTCTGCGGAGTCATGAGGG ERBB3 ENSG00000065361 3.20763229176988 [] [] 5 hSpCas9 negative selection 3503994
56083821 56083844 12 + 26780180 A375 viability (Avana lentiGuide) GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 2.98346159782981 [] [] 3 hSpCas9 negative selection 3612648
56083750 56083773 12 + 26780180 A375 viability (Avana lentiGuide) GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 -2.97266472100617 [] [] -5 hSpCas9 negative selection 3612649
56085021 56085044 12 - 26780180 A375 viability (Avana lentiGuide) AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.9252019075885 [] [] 2 hSpCas9 negative selection 3612650
56083811 56083834 12 + 26780180 A375 viability (Avana lentiGuide) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 5.54874271495061 [] [] 5 hSpCas9 negative selection 3612651
56083784 56083807 12 - 26780180 A375 viability (Avana lentiGuide) GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 7.49987963669229 [] [] 6 hSpCas9 negative selection 3612652
56080285 56080308 12 + 26780180 A375 viability (Avana lentiGuide) CACCCTCTGCGGAGTCATGAGGG ERBB3 ENSG00000065361 -3.65952876174118 [] [] -6 hSpCas9 negative selection 3612653
56083821 56083844 12 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.07596896856985949 [4] [4,3] -1 hSpCas9 positive selection 3721307
56083750 56083773 12 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 0.09939084334706061 [6] [6,6] 2 hSpCas9 positive selection 3721308
56085021 56085044 12 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.09249949119647763 [4] [6,3] 2 hSpCas9 positive selection 3721309
56083811 56083834 12 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.21857861366018022 [5] [5,4] -3 hSpCas9 positive selection 3721310
56083784 56083807 12 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.22344422569317626 [5] [4,4] -4 hSpCas9 positive selection 3721311
56080285 56080308 12 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CACCCTCTGCGGAGTCATGAGGG ERBB3 ENSG00000065361 0.020276353020927118 [4] [4,4] 0 hSpCas9 positive selection 3721312
56083821 56083844 12 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.040404086058883536 [5] [5,3] 0 hSpCas9 positive selection 3829914
56083750 56083773 12 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GTGTGTCCTGGGACTCTGAATGG ERBB3 ENSG00000065361 -0.3420325527786732 [6] [3,3] -4 hSpCas9 positive selection 3829915
56085021 56085044 12 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.15766657617526117 [5] [5,3] 4 hSpCas9 positive selection 3829916
56083811 56083834 12 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.024337350513108202 [6] [5,5] 0 hSpCas9 positive selection 3829917
56083784 56083807 12 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.46020058224899213 [5] [2,4] -5 hSpCas9 positive selection 3829918
56080285 56080308 12 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CACCCTCTGCGGAGTCATGAGGG ERBB3 ENSG00000065361 -0.22564409325945567 [4] [3,2] -3 hSpCas9 positive selection 3829919
56099725 56099748 12 - 26780180 A375 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 1.03524633712681 [] [] 5 hSpCas9 negative selection 3937269
56083811 56083834 12 + 26780180 A375 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 2.02014101024758 [] [] 9 hSpCas9 negative selection 3937270
56099715 56099738 12 + 26780180 A375 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 1.17512328772401 [] [] 6 hSpCas9 negative selection 3937271
56083854 56083877 12 - 26780180 A375 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.768553810581817 [] [] 3 hSpCas9 negative selection 3937272
56101235 56101258 12 - 26780180 A375 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 1.28714693034843 [] [] 7 hSpCas9 negative selection 3937273
56095739 56095762 12 + 26780180 A375 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 1.55470968062567 [] [] 8 hSpCas9 negative selection 3937274
56099725 56099748 12 - 26780180 HT29 viability (GeCKOv2 library) ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.614759288158505 [] [] 2 hSpCas9 negative selection 4045235
56083811 56083834 12 + 26780180 HT29 viability (GeCKOv2 library) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.642667723347206 [] [] 2 hSpCas9 negative selection 4045236
56099715 56099738 12 + 26780180 HT29 viability (GeCKOv2 library) CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.700152301899447 [] [] 2 hSpCas9 negative selection 4045237
56083854 56083877 12 - 26780180 HT29 viability (GeCKOv2 library) GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.116918608925526 [] [] 0 hSpCas9 negative selection 4045238
56101235 56101258 12 - 26780180 HT29 viability (GeCKOv2 library) TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 0.868870293996461 [] [] 3 hSpCas9 negative selection 4045239
56095739 56095762 12 + 26780180 HT29 viability (GeCKOv2 library) TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 2.37523969830864 [] [] 9 hSpCas9 negative selection 4045240
56099725 56099748 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.11383310937695357 [2] [1,1] -3 hSpCas9 positive selection 4135104
56085084 56085107 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 0.05463628653105019 [3] [2,2] 1 hSpCas9 positive selection 4135105
56083811 56083834 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.12682049430491216 [2] [0,1] -3 hSpCas9 positive selection 4135107
56083773 56083796 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.4178777612189647 [2] [0,0] -8 hSpCas9 positive selection 4135108
56084992 56085015 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.0072374646519340335 [3] [1,1] 0 hSpCas9 positive selection 4135109
56099715 56099738 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.5277128355014721 [4] [3,5] 9 hSpCas9 positive selection 4135110
56095662 56095685 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 0.03304601855813549 [1] [0,1] 0 hSpCas9 positive selection 4135111
56095739 56095762 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.21528126428262606 [3] [1,1] -5 hSpCas9 positive selection 4135112
56099725 56099748 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.05917534990667539 [2] [0,2,0,0] 0 hSpCas9 positive selection 4199126
56085084 56085107 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CAAACTTCCCATCGTAGACCTGG ERBB3 ENSG00000065361 -0.6407857032157903 [3] [0,1,0,0] -8 hSpCas9 positive selection 4199127
56083811 56083834 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.559466640375612 [0] [0,0,0,0] 4 hSpCas9 positive selection 4199129
56083773 56083796 12 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CAGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.5413779673480716 [3] [1,0,0,0] -7 hSpCas9 positive selection 4199130
56084992 56085015 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CAGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 0.07946120364904 [3] [3,1,2,0] 0 hSpCas9 positive selection 4199131
56099715 56099738 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.06224677640478232 [4] [4,2,1,0] 0 hSpCas9 positive selection 4199132
56095662 56095685 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TAGCAAAACCCATCTGACAATGG ERBB3 ENSG00000065361 -0.20768339773397526 [2] [0,0,1,0] -3 hSpCas9 positive selection 4199133
56095739 56095762 12 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.029940224048940756 [2] [0,0,0,0] 0 hSpCas9 positive selection 4199134
56083811 56083834 12 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.4789126637400697 [3] [1,1] -8 hSpCas9 positive selection 4269108
56095739 56095762 12 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5243600077384236 [2] [0,1] -8 hSpCas9 positive selection 4269109
56083854 56083877 12 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.3043582064296328 [3] [3,3] 6 hSpCas9 positive selection 4269110
56101235 56101258 12 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.8994116393611825 [3] [1,0] -9 hSpCas9 positive selection 4333373
56099725 56099748 12 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.13165955211080438 [4] [2,3] -3 hSpCas9 positive selection 4333374
56099715 56099738 12 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 -0.35758814233080954 [2] [3,0] -6 hSpCas9 positive selection 4333375
56083773 56083795 12 - 27760321 OCIAML3 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.774686613231285 [656,507] [246,286] -6 hSpCas9 negative selection 4398183
56083812 56083834 12 + 27760321 OCIAML3 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.15897446519296748 [309,264] [218,290] 1 hSpCas9 negative selection 4398184
56083853 56083875 12 + 27760321 OCIAML3 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.4979109311738249 [484,421] [240,262] -5 hSpCas9 negative selection 4398185
56084993 56085015 12 + 27760321 OCIAML3 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.870918042308078 [196,170] [84,69] -7 hSpCas9 negative selection 4398186
56085052 56085074 12 + 27760321 OCIAML3 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.027854488719724957 [1318,1081] [827,1114] 0 hSpCas9 negative selection 4398187
56083773 56083795 12 - 27760321 OCIAML2 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.03062261776036651 [656,507] [416,511] 0 hSpCas9 negative selection 4481646
56083812 56083834 12 + 27760321 OCIAML2 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.21826721439273267 [309,264] [197,200] -3 hSpCas9 negative selection 4481647
56083853 56083875 12 + 27760321 OCIAML2 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.020421698965888642 [484,421] [321,435] 0 hSpCas9 negative selection 4481648
56084993 56085015 12 + 27760321 OCIAML2 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 0.46251275902067523 [196,170] [201,207] 6 hSpCas9 negative selection 4481649
56085052 56085074 12 + 27760321 OCIAML2 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.07984490540489775 [1318,1081] [951,1112] 1 hSpCas9 negative selection 4481650
56083773 56083795 12 - 27760321 MV411 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.21930992163290858 [656,507] [289,675] 1 hSpCas9 negative selection 4565109
56083812 56083834 12 + 27760321 MV411 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.017126738166802213 [309,264] [58,378] 0 hSpCas9 negative selection 4565110
56083853 56083875 12 + 27760321 MV411 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.6030067558279277 [484,421] [140,279] -4 hSpCas9 negative selection 4565111
56084993 56085015 12 + 27760321 MV411 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 1.52730660260627 [196,170] [4,865] 9 hSpCas9 negative selection 4565112
56085052 56085074 12 + 27760321 MV411 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.556686972275398 [1318,1081] [1205,1089] 4 hSpCas9 negative selection 4565113
56083773 56083795 12 - 27760321 HL60 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.30704989615380823 [656,507] [714,445] 4 hSpCas9 negative selection 4648572
56083812 56083834 12 + 27760321 HL60 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.014228406137982819 [309,264] [167,308] 0 hSpCas9 negative selection 4648573
56083853 56083875 12 + 27760321 HL60 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.2861056237781213 [484,421] [255,352] -3 hSpCas9 negative selection 4648574
56084993 56085015 12 + 27760321 HL60 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -1.7180052703163078 [196,170] [47,42] -9 hSpCas9 negative selection 4648575
56085052 56085074 12 + 27760321 HL60 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.3222059124185066 [1318,1081] [1274,1161] 4 hSpCas9 negative selection 4648576
56083773 56083795 12 - 27760321 HT1080 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.21960551658191485 [507,396] [129,181] -1 hSpCas9 negative selection 4732035
56083812 56083834 12 + 27760321 HT1080 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.349939442453568 [264,206] [44,27] -5 hSpCas9 negative selection 4732036
56083853 56083875 12 + 27760321 HT1080 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.6920622881833959 [421,329] [94,402] 3 hSpCas9 negative selection 4732037
56084993 56085015 12 + 27760321 HT1080 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -1.459849292341692 [170,133] [23,19] -5 hSpCas9 negative selection 4732038
56085052 56085074 12 + 27760321 HT1080 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 1.90247531687983 [1081,844] [2267,522] 8 hSpCas9 negative selection 4732039
56083773 56083795 12 - 27760321 HT29 viability after 7 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.06850459442262419 [507,396] [517,569,569] -1 hSpCas9 negative selection 4815498
56083812 56083834 12 + 27760321 HT29 viability after 7 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.27328623384848216 [264,206] [168,410,163] -4 hSpCas9 negative selection 4815499
56083853 56083875 12 + 27760321 HT29 viability after 7 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.023599593836969412 [421,329] [656,371,468] 0 hSpCas9 negative selection 4815500
56084993 56085015 12 + 27760321 HT29 viability after 7 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.6033015027430266 [170,133] [117,121,144] -7 hSpCas9 negative selection 4815501
56085052 56085074 12 + 27760321 HT29 viability after 7 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.5765702730808484 [1081,844] [2131,1781,1671] 8 hSpCas9 negative selection 4815502
56083773 56083795 12 - 27760321 HT29 viability after 25 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.2528542755247366 [507,396] [370,520,410] -3 hSpCas9 negative selection 4898961
56083812 56083834 12 + 27760321 HT29 viability after 25 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.8522436389259219 [264,206] [122,156,171] -6 hSpCas9 negative selection 4898962
56083853 56083875 12 + 27760321 HT29 viability after 25 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.06456340737781197 [421,329] [510,285,557] 0 hSpCas9 negative selection 4898963
56084993 56085015 12 + 27760321 HT29 viability after 25 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.18146509908983055 [170,133] [212,117,122] -2 hSpCas9 negative selection 4898964
56085052 56085074 12 + 27760321 HT29 viability after 25 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.6513226051430399 [1081,844] [1761,1698,1721] 7 hSpCas9 negative selection 4898965
56083773 56083795 12 - 27760321 HT29 viability after 22 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.07958482553077706 [507,396] [339,591,557] -1 hSpCas9 negative selection 4982424
56083812 56083834 12 + 27760321 HT29 viability after 22 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6940648454329509 [264,206] [180,113,210] -5 hSpCas9 negative selection 4982425
56083853 56083875 12 + 27760321 HT29 viability after 22 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.27432543752590643 [421,329] [562,412,600] 3 hSpCas9 negative selection 4982426
56084993 56085015 12 + 27760321 HT29 viability after 22 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.3983394285832744 [170,133] [103,183,113] -4 hSpCas9 negative selection 4982427
56085052 56085074 12 + 27760321 HT29 viability after 22 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.408769134616243 [1081,844] [1474,1619,1339] 4 hSpCas9 negative selection 4982428
56083773 56083795 12 - 27760321 HT29 viability after 19 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.23124107250164533 [507,396] [838,656,359] 2 hSpCas9 negative selection 5065887
56083812 56083834 12 + 27760321 HT29 viability after 19 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.7795017783231789 [264,206] [158,79,229] -6 hSpCas9 negative selection 5065888
56083853 56083875 12 + 27760321 HT29 viability after 19 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.23916139457375846 [421,329] [520,430,164] -2 hSpCas9 negative selection 5065889
56084993 56085015 12 + 27760321 HT29 viability after 19 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.4183213953687257 [170,133] [236,123,44] -4 hSpCas9 negative selection 5065890
56085052 56085074 12 + 27760321 HT29 viability after 19 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.4131593925257784 [1081,844] [1646,1225,1543] 4 hSpCas9 negative selection 5065891
56083773 56083795 12 - 27760321 HT29 viability after 16 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.07198622633319518 [507,396] [300,589,533] -1 hSpCas9 negative selection 5149350
56083812 56083834 12 + 27760321 HT29 viability after 16 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.04760347128635689 [264,206] [332,244,195] 0 hSpCas9 negative selection 5149351
56083853 56083875 12 + 27760321 HT29 viability after 16 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.24173871241353867 [421,329] [392,351,325] -3 hSpCas9 negative selection 5149352
56084993 56085015 12 + 27760321 HT29 viability after 16 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.7916397633993442 [170,133] [138,81,78] -6 hSpCas9 negative selection 5149353
56085052 56085074 12 + 27760321 HT29 viability after 16 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.5688109085104851 [1081,844] [1688,1609,1505] 6 hSpCas9 negative selection 5149354
56083773 56083795 12 - 27760321 HT29 viability after 13 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.2049958829461745 [507,396] [389,598,381] -2 hSpCas9 negative selection 5232813
56083812 56083834 12 + 27760321 HT29 viability after 13 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5968752318031277 [264,206] [101,255,184] -6 hSpCas9 negative selection 5232814
56083853 56083875 12 + 27760321 HT29 viability after 13 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.30164367837615746 [421,329] [463,251,345] -4 hSpCas9 negative selection 5232815
56084993 56085015 12 + 27760321 HT29 viability after 13 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.4386571038318321 [170,133] [84,179,126] -5 hSpCas9 negative selection 5232816
56085052 56085074 12 + 27760321 HT29 viability after 13 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.5211189925136113 [1081,844] [1492,1521,1785] 6 hSpCas9 negative selection 5232817
56083773 56083795 12 - 27760321 HT29 viability after 10 days AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 -0.2298807491035393 [507,396] [514,500,430] -3 hSpCas9 negative selection 5316276
56083812 56083834 12 + 27760321 HT29 viability after 10 days ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.3038889587145112 [264,206] [405,299,382] 4 hSpCas9 negative selection 5316277
56083853 56083875 12 + 27760321 HT29 viability after 10 days ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 -0.24053971981072464 [421,329] [473,419,300] -3 hSpCas9 negative selection 5316278
56084993 56085015 12 + 27760321 HT29 viability after 10 days AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 -0.48836910843983805 [170,133] [228,148,31] -6 hSpCas9 negative selection 5316279
56085052 56085074 12 + 27760321 HT29 viability after 10 days CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.4285824121117714 [1081,844] [1413,1685,1755] 6 hSpCas9 negative selection 5316280
56083773 56083795 12 - 27760321 MOLM13 viability AGCATCGCCGGTCACACTCAGG ERBB3 ENSG00000065361 0.7344382521410695 [656,507] [423,643] 5 hSpCas9 negative selection 5399739
56083812 56083834 12 + 27760321 MOLM13 viability ACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.5266382066498854 [309,264] [114,5] -7 hSpCas9 negative selection 5399740
56083853 56083875 12 + 27760321 MOLM13 viability ACCTTGAGATTGTGCTCACGGG ERBB3 ENSG00000065361 0.4731913990372411 [484,421] [544,191] 3 hSpCas9 negative selection 5399741
56084993 56085015 12 + 27760321 MOLM13 viability AGTGGATTCGAGAAGTGACAGG ERBB3 ENSG00000065361 0.7347811608017404 [196,170] [93,238] 5 hSpCas9 negative selection 5399742
56085052 56085074 12 + 27760321 MOLM13 viability CCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 1.156506937369334 [1318,1081] [1514,1491] 7 hSpCas9 negative selection 5399743
56080233 56080256 12 - 27661255 K562 viability GCCCCTAGGCTAGGACATCGAGG ERBB3 ENSG00000065361 0.049867197746490066 [436,508] [429,355] 1 dCas9-KRAB negative selection 5477695
56083811 56083834 12 + 27260156 BXPC3 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.6218670959702979 [532] [188,208,162,155] -9 hSpCas9 negative selection 5541568
56095739 56095762 12 + 27260156 BXPC3 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.27746905056506344 [222] [252,117,194,200] -6 hSpCas9 negative selection 5541569
56083854 56083877 12 - 27260156 BXPC3 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.8060741540159178 [858] [429,512,513,615] -9 hSpCas9 negative selection 5541570
56101235 56101258 12 - 27260156 BXPC3 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.0902537682335995 [489] [272,200,258,224] -9 hSpCas9 negative selection 5605833
56099725 56099748 12 - 27260156 BXPC3 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -1.4302721196627022 [1189] [457,402,496,493] -9 hSpCas9 negative selection 5605834
56099715 56099738 12 + 27260156 BXPC3 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.48726094554608734 [385] [573,489,656,539] 8 hSpCas9 negative selection 5605835
56083811 56083834 12 + 27260156 A673 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.007566769093532405 [532] [732,651,577,590] 0 hSpCas9 negative selection 5662819
56095739 56095762 12 + 27260156 A673 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.15808372524118441 [222] [221,296,258,173] -4 hSpCas9 negative selection 5662820
56083854 56083877 12 - 27260156 A673 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.25024835486498676 [858] [1216,1150,1131,1416] 6 hSpCas9 negative selection 5662821
56101235 56101258 12 - 27260156 A673 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.2401455310112021 [489] [547,408,561,478] -5 hSpCas9 negative selection 5727084
56099725 56099748 12 - 27260156 A673 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.15742775272308163 [1189] [1373,1335,1120,1302] -4 hSpCas9 negative selection 5727085
56099715 56099738 12 + 27260156 A673 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.37309093066367993 [385] [638,564,662,533] 8 hSpCas9 negative selection 5727086
56083811 56083834 12 + 27260156 A375 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.8357272818222581 [532] [259,364,444,327] -8 hSpCas9 negative selection 5784070
56095739 56095762 12 + 27260156 A375 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.9254496152642164 [222] [117,201,109,127] -8 hSpCas9 negative selection 5784071
56083854 56083877 12 - 27260156 A375 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.15391572972416434 [858] [976,975,616,1028] -2 hSpCas9 negative selection 5784072
56101235 56101258 12 - 27260156 A375 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.5669205450445602 [489] [554,270,426,287] -6 hSpCas9 negative selection 5848335
56099725 56099748 12 - 27260156 A375 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.6086179351814667 [1189] [1015,1086,784,793] -7 hSpCas9 negative selection 5848336
56099715 56099738 12 + 27260156 A375 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.5731366889856842 [385] [715,654,742,575] 8 hSpCas9 negative selection 5848337
56083811 56083834 12 + 27260156 COLO741 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.15263635949449816 [532] [739,715,406] -3 hSpCas9 negative selection 5905321
56095739 56095762 12 + 27260156 COLO741 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.4142775232403675 [222] [350,166,139] -7 hSpCas9 negative selection 5905322
56083854 56083877 12 - 27260156 COLO741 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.3530284374520911 [858] [1573,1343,1305] 7 hSpCas9 negative selection 5905323
56101235 56101258 12 - 27260156 COLO741 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.43671029346388396 [489] [411,431,532] -7 hSpCas9 negative selection 5969586
56099725 56099748 12 - 27260156 COLO741 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.10940440494476822 [1189] [1428,1558,1250] -2 hSpCas9 negative selection 5969587
56099715 56099738 12 + 27260156 COLO741 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.4794752757839499 [385] [693,486,866] 8 hSpCas9 negative selection 5969588
56083811 56083834 12 + 27260156 CAL120 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.7049375661700246 [532] [660,205,391] -7 hSpCas9 negative selection 6026572
56095739 56095762 12 + 27260156 CAL120 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5329669594370201 [222] [227,119,231] -6 hSpCas9 negative selection 6026573
56083854 56083877 12 - 27260156 CAL120 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.21727098283812418 [858] [871,851,1024] -3 hSpCas9 negative selection 6026574
56101235 56101258 12 - 27260156 CAL120 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.5267235945624661 [489] [523,464,297] -6 hSpCas9 negative selection 6090837
56099725 56099748 12 - 27260156 CAL120 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.632946581755017 [1189] [1456,812,674] -7 hSpCas9 negative selection 6090838
56099715 56099738 12 + 27260156 CAL120 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.7658796273461934 [385] [861,679,912] 9 hSpCas9 negative selection 6090839
56083811 56083834 12 + 27260156 CADOES1 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.4297361441245554 [532] [309,350,294,521] -6 hSpCas9 negative selection 6147823
56095739 56095762 12 + 27260156 CADOES1 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.2805582347814144 [222] [166,39,220,257] -5 hSpCas9 negative selection 6147824
56083854 56083877 12 - 27260156 CADOES1 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.2156513374292377 [858] [944,886,868,1012] 3 hSpCas9 negative selection 6147825
56101235 56101258 12 - 27260156 CADOES1 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.8868802775507649 [489] [353,121,294,212] -9 hSpCas9 negative selection 6212088
56099725 56099748 12 - 27260156 CADOES1 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.3995638471371181 [1189] [675,834,712,1143] -6 hSpCas9 negative selection 6212089
56099715 56099738 12 + 27260156 CADOES1 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.28093336757105225 [385] [542,511,320,365] 5 hSpCas9 negative selection 6212090
56083811 56083834 12 + 27260156 EWS502 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.3881500623320021 [532] [363,547,343,472] -6 hSpCas9 negative selection 6269074
56095739 56095762 12 + 27260156 EWS502 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.3833804695014895 [222] [310,74,122,203] -6 hSpCas9 negative selection 6269075
56083854 56083877 12 - 27260156 EWS502 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.18686472102077345 [858] [982,1026,1039,1099] 3 hSpCas9 negative selection 6269076
56101235 56101258 12 - 27260156 EWS502 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.0586186607236217 [489] [221,266,266,241] -9 hSpCas9 negative selection 6333339
56099725 56099748 12 - 27260156 EWS502 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.4326931825071948 [1189] [764,898,976,1126] -6 hSpCas9 negative selection 6333340
56099715 56099738 12 + 27260156 EWS502 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.02509665405420569 [385] [325,376,572,399] 0 hSpCas9 negative selection 6333341
56083811 56083834 12 + 27260156 EW8 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5904008574492488 [532] [299,330,259,261] -8 hSpCas9 negative selection 6390325
56095739 56095762 12 + 27260156 EW8 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.7162532662496899 [222] [119,90,113,114] -8 hSpCas9 negative selection 6390326
56083854 56083877 12 - 27260156 EW8 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.08782472265260244 [858] [973,638,732,637] 1 hSpCas9 negative selection 6390327
56101235 56101258 12 - 27260156 EW8 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.843927724555532 [489] [272,283,200,135] -9 hSpCas9 negative selection 6454590
56099725 56099748 12 - 27260156 EW8 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.3737296802526655 [1189] [733,968,603,691] -6 hSpCas9 negative selection 6454591
56099715 56099738 12 + 27260156 EW8 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.7118803795869091 [385] [549,727,433,354] 9 hSpCas9 negative selection 6454592
56083811 56083834 12 + 27260156 CORL105 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.3319815273441572 [532] [469,565,566,388] -6 hSpCas9 negative selection 6511576
56095739 56095762 12 + 27260156 CORL105 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 0.09193661248344653 [222] [366,295,271,179] 1 hSpCas9 negative selection 6511577
56083854 56083877 12 - 27260156 CORL105 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.28331626329031834 [858] [1219,1172,1451,1086] 5 hSpCas9 negative selection 6511578
56101235 56101258 12 - 27260156 CORL105 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.5343312789054673 [489] [426,359,583,244] -7 hSpCas9 negative selection 6575841
56099725 56099748 12 - 27260156 CORL105 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.1923938540436898 [1189] [1381,1007,1388,1133] -4 hSpCas9 negative selection 6575842
56099715 56099738 12 + 27260156 CORL105 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.1983187495150845 [385] [541,446,513,571] 3 hSpCas9 negative selection 6575843
56083811 56083834 12 + 27260156 HS294T viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.3795620158752915 [532] [55,43,115,108] -9 hSpCas9 negative selection 6632827
56095739 56095762 12 + 27260156 HS294T viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5609685068440124 [222] [34,71,61,67] -7 hSpCas9 negative selection 6632828
56083854 56083877 12 - 27260156 HS294T viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.11794565406375634 [858] [256,529,310,343] 1 hSpCas9 negative selection 6632829
56101235 56101258 12 - 27260156 HS294T viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.9779936084711437 [489] [68,77,77,175] -8 hSpCas9 negative selection 6697092
56099725 56099748 12 - 27260156 HS294T viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.8777984485850694 [1189] [268,216,263,249] -8 hSpCas9 negative selection 6697093
56099715 56099738 12 + 27260156 HS294T viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.32379294656362423 [385] [193,212,145,192] 4 hSpCas9 negative selection 6697094
56083811 56083834 12 + 27260156 HCC44 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.3206593596403486 [532] [308,228,301,144] -9 hSpCas9 negative selection 6754078
56095739 56095762 12 + 27260156 HCC44 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5488295124772606 [222] [172,263,88,135] -7 hSpCas9 negative selection 6754079
56083854 56083877 12 - 27260156 HCC44 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.021819857672825016 [858] [1182,768,1125,933] 0 hSpCas9 negative selection 6754080
56101235 56101258 12 - 27260156 HCC44 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.8632563207413194 [489] [330,236,517,182] -8 hSpCas9 negative selection 6818343
56099725 56099748 12 - 27260156 HCC44 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.02766692191418252 [1189] [1433,976,1732,1258] 0 hSpCas9 negative selection 6818344
56099715 56099738 12 + 27260156 HCC44 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.1948801984785457 [385] [634,343,310,699] 3 hSpCas9 negative selection 6818345
56083811 56083834 12 + 27260156 G402 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.20861429234775303 [532] [450,847,737,228] -3 hSpCas9 negative selection 6875329
56095739 56095762 12 + 27260156 G402 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 0.4703082279569837 [222] [323,316,364,483] 6 hSpCas9 negative selection 6875330
56083854 56083877 12 - 27260156 G402 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.15615159961690006 [858] [1694,1223,1195,656] 2 hSpCas9 negative selection 6875331
56101235 56101258 12 - 27260156 G402 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.3056586185915313 [489] [471,603,539,329] -4 hSpCas9 negative selection 6939594
56099725 56099748 12 - 27260156 G402 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.3463073189880441 [1189] [1446,867,958,1309] -4 hSpCas9 negative selection 6939595
56099715 56099738 12 + 27260156 G402 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 1.2237580629391362 [385] [894,1151,728,1569] 9 hSpCas9 negative selection 6939596
56083811 56083834 12 + 27260156 L33 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.9012358024919767 [532] [321,98,187,277] -9 hSpCas9 negative selection 6996580
56095739 56095762 12 + 27260156 L33 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.6504394678812484 [222] [183,56,79,116] -9 hSpCas9 negative selection 6996581
56083854 56083877 12 - 27260156 L33 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.021267533741661127 [858] [935,325,520,822] 0 hSpCas9 negative selection 6996582
56101235 56101258 12 - 27260156 L33 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.0656556574404832 [489] [179,95,139,299] -9 hSpCas9 negative selection 7060845
56099725 56099748 12 - 27260156 L33 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -1.2178712375666345 [1189] [513,205,360,455] -9 hSpCas9 negative selection 7060846
56099715 56099738 12 + 27260156 L33 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.48685007477654635 [385] [571,215,251,660] 8 hSpCas9 negative selection 7060847
56083811 56083834 12 + 27260156 K562 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.619551971303707 [532] [187,111,164,150] -9 hSpCas9 negative selection 7117831
56095739 56095762 12 + 27260156 K562 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 0.14753688581672397 [222] [433,138,254,77] 1 hSpCas9 negative selection 7117832
56083854 56083877 12 - 27260156 K562 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.3530652130756844 [858] [801,1048,985,1035] 4 hSpCas9 negative selection 7117833
56101235 56101258 12 - 27260156 K562 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.7959315101726554 [489] [102,138,119,135] -9 hSpCas9 negative selection 7182096
56099725 56099748 12 - 27260156 K562 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.5399288467052861 [1189] [961,821,702,469] -6 hSpCas9 negative selection 7182097
56099715 56099738 12 + 27260156 K562 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.8831767171405774 [385] [548,780,680,526] 9 hSpCas9 negative selection 7182098
56083811 56083834 12 + 27260156 HT29 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.09344723765451103 [532] [618,766,550,513] -2 hSpCas9 negative selection 7239082
56095739 56095762 12 + 27260156 HT29 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.2881043483175576 [222] [233,221,295,144] -5 hSpCas9 negative selection 7239083
56083854 56083877 12 - 27260156 HT29 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.44186924868651545 [858] [1690,1657,1315,1081] 8 hSpCas9 negative selection 7239084
56101235 56101258 12 - 27260156 HT29 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.43761385193969893 [489] [492,531,401,351] -7 hSpCas9 negative selection 7303347
56099725 56099748 12 - 27260156 HT29 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.05609084852306534 [1189] [1691,1682,1419,1268] 1 hSpCas9 negative selection 7303348
56099715 56099738 12 + 27260156 HT29 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.28000912512591064 [385] [757,528,520,487] 5 hSpCas9 negative selection 7303349
56083811 56083834 12 + 27260156 MHHES1 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5416367518847086 [532] [406,379,531,335] -7 hSpCas9 negative selection 7360333
56095739 56095762 12 + 27260156 MHHES1 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.24018905720249162 [222] [237,164,253,191] -4 hSpCas9 negative selection 7360334
56083854 56083877 12 - 27260156 MHHES1 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.43635273062072577 [858] [1513,1437,1290,1059] 7 hSpCas9 negative selection 7360335
56101235 56101258 12 - 27260156 MHHES1 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.6366283955219695 [489] [335,506,342,260] -8 hSpCas9 negative selection 7424598
56099725 56099748 12 - 27260156 MHHES1 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.02425806090990057 [1189] [1562,1276,1223,1223] 0 hSpCas9 negative selection 7424599
56099715 56099738 12 + 27260156 MHHES1 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.2956393033233036 [385] [547,397,536,608] 5 hSpCas9 negative selection 7424600
56083811 56083834 12 + 27260156 MEWO viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.3297769213760395 [532] [347,343,488] -6 hSpCas9 negative selection 7481584
56095739 56095762 12 + 27260156 MEWO viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.690243031770198 [222] [139,116,132] -8 hSpCas9 negative selection 7481585
56083854 56083877 12 - 27260156 MEWO viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.2563121631262306 [858] [1326,875,747] 5 hSpCas9 negative selection 7481586
56101235 56101258 12 - 27260156 MEWO viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.2886227137355613 [489] [454,430,254] -6 hSpCas9 negative selection 7545849
56099725 56099748 12 - 27260156 MEWO viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.03796927001452288 [1189] [1225,1111,1106] 0 hSpCas9 negative selection 7545850
56099715 56099738 12 + 27260156 MEWO viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.30741564527945775 [385] [335,464,517] 6 hSpCas9 negative selection 7545851
56083811 56083834 12 + 27260156 LNCAPCLONEFGC viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5819173630282484 [532] [346,394,303,235] -7 hSpCas9 negative selection 7602835
56095739 56095762 12 + 27260156 LNCAPCLONEFGC viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.10651828786515316 [222] [148,175,194,232] -2 hSpCas9 negative selection 7602836
56083854 56083877 12 - 27260156 LNCAPCLONEFGC viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.17586445278362506 [858] [809,765,1429,599] 2 hSpCas9 negative selection 7602837
56101235 56101258 12 - 27260156 LNCAPCLONEFGC viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.369573355508656 [489] [254,439,320,349] -5 hSpCas9 negative selection 7667100
56099725 56099748 12 - 27260156 LNCAPCLONEFGC viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.280455838154964 [1189] [829,943,975,809] -4 hSpCas9 negative selection 7667101
56099715 56099738 12 + 27260156 LNCAPCLONEFGC viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.46213166733861666 [385] [650,359,392,513] 7 hSpCas9 negative selection 7667102
56083811 56083834 12 + 27260156 PANC0327 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.03230095376194 [532] [232,216,279,197] -8 hSpCas9 negative selection 7724086
56095739 56095762 12 + 27260156 PANC0327 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.8368648295174304 [222] [99,31,191,128] -8 hSpCas9 negative selection 7724087
56083854 56083877 12 - 27260156 PANC0327 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.38487758851421744 [858] [873,295,461,765] -5 hSpCas9 negative selection 7724088
56101235 56101258 12 - 27260156 PANC0327 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.15772981578528653 [489] [267,158,293,858] -2 hSpCas9 negative selection 7788351
56099725 56099748 12 - 27260156 PANC0327 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.8193271854429267 [1189] [612,643,415,717] -8 hSpCas9 negative selection 7788352
56099715 56099738 12 + 27260156 PANC0327 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.35978999198265027 [385] [611,339,467,366] 5 hSpCas9 negative selection 7788353
56083811 56083834 12 + 27260156 NCIH2009 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6621970776515572 [532] [473,393,544] -7 hSpCas9 negative selection 7845337
56095739 56095762 12 + 27260156 NCIH2009 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.3622114394425835 [222] [232,291,198] -5 hSpCas9 negative selection 7845338
56083854 56083877 12 - 27260156 NCIH2009 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.41847698997769833 [858] [2026,1381,1487] 6 hSpCas9 negative selection 7845339
56101235 56101258 12 - 27260156 NCIH2009 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.7171637803954293 [489] [466,449,340] -7 hSpCas9 negative selection 7909602
56099725 56099748 12 - 27260156 NCIH2009 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.41084470956394537 [1189] [1466,1218,1106] -5 hSpCas9 negative selection 7909603
56099715 56099738 12 + 27260156 NCIH2009 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.5343019257062438 [385] [711,678,938] 7 hSpCas9 negative selection 7909604
56083811 56083834 12 + 27260156 NCIH1373 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.9392053464285821 [532] [161,103,388,158] -7 hSpCas9 negative selection 7966588
56095739 56095762 12 + 27260156 NCIH1373 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.028256238057317695 [222] [233,76,177,137] 0 hSpCas9 negative selection 7966589
56083854 56083877 12 - 27260156 NCIH1373 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.6457440674127897 [858] [481,536,746,178] -6 hSpCas9 negative selection 7966590
56101235 56101258 12 - 27260156 NCIH1373 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.078086135768359 [489] [69,384,116,114] -8 hSpCas9 negative selection 8030853
56099725 56099748 12 - 27260156 NCIH1373 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.8870147682106763 [1189] [614,561,412,350] -7 hSpCas9 negative selection 8030854
56099715 56099738 12 + 27260156 NCIH1373 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.8955653706217955 [385] [1006,801,704,191] 8 hSpCas9 negative selection 8030855
56083811 56083834 12 + 27260156 PATU8902 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.8324589864786491 [532] [683,419,237,357] -7 hSpCas9 negative selection 8087839
56095739 56095762 12 + 27260156 PATU8902 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5181297138609593 [222] [261,103,150,384] -5 hSpCas9 negative selection 8087840
56083854 56083877 12 - 27260156 PATU8902 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.49649627861562173 [858] [1009,847,473,1188] -5 hSpCas9 negative selection 8087841
56101235 56101258 12 - 27260156 PATU8902 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.3177795366841134 [489] [221,797,419,815] -3 hSpCas9 negative selection 8152104
56099725 56099748 12 - 27260156 PATU8902 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.5475578403876586 [1189] [808,1485,1088,1162] -5 hSpCas9 negative selection 8152105
56099715 56099738 12 + 27260156 PATU8902 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.5575660343292812 [385] [578,881,722,1022] 6 hSpCas9 negative selection 8152106
56083811 56083834 12 + 27260156 PANC1 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.14523986593659416 [532] [298,606,518,600] 2 hSpCas9 negative selection 8209090
56095739 56095762 12 + 27260156 PANC1 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.07680336880382876 [222] [139,324,151,142] -1 hSpCas9 negative selection 8209091
56083854 56083877 12 - 27260156 PANC1 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.5315442719284884 [858] [987,1167,1243,899] 8 hSpCas9 negative selection 8209092
56101235 56101258 12 - 27260156 PANC1 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.45732958419833747 [489] [188,466,277,319] -6 hSpCas9 negative selection 8273355
56099725 56099748 12 - 27260156 PANC1 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.03147598141175756 [1189] [1331,830,1010,951] 0 hSpCas9 negative selection 8273356
56099715 56099738 12 + 27260156 PANC1 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.17118003544076407 [385] [346,608,432,179] 2 hSpCas9 negative selection 8273357
56083811 56083834 12 + 27260156 PANC0813 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.3694266797423679 [532] [415,474,456,577] -5 hSpCas9 negative selection 8330341
56095739 56095762 12 + 27260156 PANC0813 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5739371125612562 [222] [221,163,167,154] -7 hSpCas9 negative selection 8330342
56083854 56083877 12 - 27260156 PANC0813 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.3762258279598458 [858] [1428,1215,1422,1186] 6 hSpCas9 negative selection 8330343
56101235 56101258 12 - 27260156 PANC0813 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.4732509058578653 [489] [711,266,329,377] -6 hSpCas9 negative selection 8394606
56099725 56099748 12 - 27260156 PANC0813 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.20365423309944797 [1189] [1164,1250,1138,1288] -3 hSpCas9 negative selection 8394607
56099715 56099738 12 + 27260156 PANC0813 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.6139562765336357 [385] [662,410,758,925] 8 hSpCas9 negative selection 8394608
56083811 56083834 12 + 27260156 RDES viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -1.3351187720057243 [532] [222,211,296,240] -9 hSpCas9 negative selection 8451592
56095739 56095762 12 + 27260156 RDES viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.549491864476197 [222] [153,153,159,243] -7 hSpCas9 negative selection 8451593
56083854 56083877 12 - 27260156 RDES viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 -0.2790874214997967 [858] [749,819,891,777] -5 hSpCas9 negative selection 8451594
56101235 56101258 12 - 27260156 RDES viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.1615748326833553 [489] [213,242,298,254] -9 hSpCas9 negative selection 8515857
56099725 56099748 12 - 27260156 RDES viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.5666377187103372 [1189] [785,786,1013,1163] -7 hSpCas9 negative selection 8515858
56099715 56099738 12 + 27260156 RDES viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.629469163683971 [385] [528,653,689,927] 8 hSpCas9 negative selection 8515859
56083811 56083834 12 + 27260156 PC3 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.059041764726860776 [532] [457,384,698,533] -1 hSpCas9 negative selection 8572843
56095739 56095762 12 + 27260156 PC3 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.8329607954969613 [222] [44,136,234,152] -9 hSpCas9 negative selection 8572844
56083854 56083877 12 - 27260156 PC3 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.5593832760644761 [858] [961,1173,1804,1308] 9 hSpCas9 negative selection 8572845
56101235 56101258 12 - 27260156 PC3 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.43004930506987876 [489] [245,301,451,507] -7 hSpCas9 negative selection 8637108
56099725 56099748 12 - 27260156 PC3 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 0.062445743397547826 [1189] [907,1117,2023,1222] 1 hSpCas9 negative selection 8637109
56099715 56099738 12 + 27260156 PC3 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.24847148982740747 [385] [237,466,741,553] 5 hSpCas9 negative selection 8637110
56083811 56083834 12 + 27260156 PATU8988T viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.40573796357199754 [532] [385,357,474,326] -6 hSpCas9 negative selection 8694094
56095739 56095762 12 + 27260156 PATU8988T viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5321543852523352 [222] [138,100,189,161] -7 hSpCas9 negative selection 8694095
56083854 56083877 12 - 27260156 PATU8988T viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.3304775142250598 [858] [1308,1121,962,766] 5 hSpCas9 negative selection 8694096
56101235 56101258 12 - 27260156 PATU8988T viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.6055140045034597 [489] [265,345,214,431] -7 hSpCas9 negative selection 8758359
56099725 56099748 12 - 27260156 PATU8988T viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.14036619771897252 [1189] [1156,1006,930,1078] -2 hSpCas9 negative selection 8758360
56099715 56099738 12 + 27260156 PATU8988T viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.3900360601111963 [385] [490,537,366,571] 6 hSpCas9 negative selection 8758361
56083811 56083834 12 + 27260156 T47D viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.7429772305874427 [532] [391,268,408,423] -9 hSpCas9 negative selection 8815345
56095739 56095762 12 + 27260156 T47D viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.4230593172685202 [222] [196,159,214,205] -7 hSpCas9 negative selection 8815346
56083854 56083877 12 - 27260156 T47D viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.16317275397503916 [858] [1184,1063,1098,1139] 3 hSpCas9 negative selection 8815347
56101235 56101258 12 - 27260156 T47D viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.7963309208519846 [489] [281,383,271,373] -9 hSpCas9 negative selection 8879610
56099725 56099748 12 - 27260156 T47D viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.3243191522446309 [1189] [1133,1076,1055,1166] -6 hSpCas9 negative selection 8879611
56099715 56099738 12 + 27260156 T47D viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.2468305895052311 [385] [572,449,499,621] 5 hSpCas9 negative selection 8879612
56083811 56083834 12 + 27260156 SU8686 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6811731196033995 [532] [283,338,304,402] -7 hSpCas9 negative selection 8936596
56095739 56095762 12 + 27260156 SU8686 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.36542613209530184 [222] [155,106,144,308] -6 hSpCas9 negative selection 8936597
56083854 56083877 12 - 27260156 SU8686 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.27928558425030947 [858] [1053,1029,960,1085] 5 hSpCas9 negative selection 8936598
56101235 56101258 12 - 27260156 SU8686 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -1.1254124701351402 [489] [240,231,224,180] -8 hSpCas9 negative selection 9000861
56099725 56099748 12 - 27260156 SU8686 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.34455868477284934 [1189] [1003,683,930,1149] -5 hSpCas9 negative selection 9000862
56099715 56099738 12 + 27260156 SU8686 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.3594288470533136 [385] [457,421,437,684] 6 hSpCas9 negative selection 9000863
56083811 56083834 12 + 27260156 SKES1 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5852678041280613 [532] [451,421,308,263] -8 hSpCas9 negative selection 9057847
56095739 56095762 12 + 27260156 SKES1 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5532736043246804 [222] [121,175,168,137] -8 hSpCas9 negative selection 9057848
56083854 56083877 12 - 27260156 SKES1 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.23894154938445156 [858] [1142,1001,991,924] 5 hSpCas9 negative selection 9057849
56101235 56101258 12 - 27260156 SKES1 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.44873362664315586 [489] [508,348,231,359] -7 hSpCas9 negative selection 9122112
56099725 56099748 12 - 27260156 SKES1 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.29036863556113524 [1189] [1162,1030,949,784] -6 hSpCas9 negative selection 9122113
56099715 56099738 12 + 27260156 SKES1 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.19700854881898616 [385] [503,538,379,367] 4 hSpCas9 negative selection 9122114
56083811 56083834 12 + 27260156 TOV112D viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.5504488559424451 [532] [425,386,358,297] -8 hSpCas9 negative selection 9179098
56095739 56095762 12 + 27260156 TOV112D viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.4326915978738448 [222] [170,146,190,148] -7 hSpCas9 negative selection 9179099
56083854 56083877 12 - 27260156 TOV112D viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.07736427620825603 [858] [1148,1028,790,715] 1 hSpCas9 negative selection 9179100
56101235 56101258 12 - 27260156 TOV112D viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.502726575364545 [489] [248,432,296,416] -7 hSpCas9 negative selection 9243363
56099725 56099748 12 - 27260156 TOV112D viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.15074276125630215 [1189] [1091,1322,919,1021] -3 hSpCas9 negative selection 9243364
56099715 56099738 12 + 27260156 TOV112D viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.006061305902790748 [385] [376,555,321,338] 0 hSpCas9 negative selection 9243365
56083811 56083834 12 + 27260156 TC71 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.4792361693774093 [532] [384,409,395,451] -8 hSpCas9 negative selection 9300349
56095739 56095762 12 + 27260156 TC71 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.8976378871870252 [222] [90,182,137,99] -9 hSpCas9 negative selection 9300350
56083854 56083877 12 - 27260156 TC71 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.2229987670025939 [858] [1012,1062,1094,1131] 5 hSpCas9 negative selection 9300351
56101235 56101258 12 - 27260156 TC71 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.4854459002377004 [489] [401,349,423,318] -8 hSpCas9 negative selection 9364614
56099725 56099748 12 - 27260156 TC71 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.16315913020093564 [1189] [1218,1055,1059,1227] -4 hSpCas9 negative selection 9364615
56099715 56099738 12 + 27260156 TC71 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.1988414996942634 [385] [522,430,446,499] 5 hSpCas9 negative selection 9364616
56083811 56083834 12 + 27260156 TC32 viability CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.6009430242020162 [532] [261,272,396,415] -8 hSpCas9 negative selection 9421600
56095739 56095762 12 + 27260156 TC32 viability TTCTCTACTGGCGTGGGCGCCGG ERBB3 ENSG00000065361 -0.5988601636279192 [222] [183,68,226,98] -8 hSpCas9 negative selection 9421601
56083854 56083877 12 - 27260156 TC32 viability GTCCCGTGAGCACAATCTCAAGG ERBB3 ENSG00000065361 0.13637929959821382 [858] [813,570,1378,952] 2 hSpCas9 negative selection 9421602
56101235 56101258 12 - 27260156 TC32 viability TGGTAGGCGCTATCTCCGCGTGG ERBB3 ENSG00000065361 -0.8567214815765845 [489] [234,170,312,331] -9 hSpCas9 negative selection 9485865
56099725 56099748 12 - 27260156 TC32 viability ACCTTTATGACCAGATACCGTGG ERBB3 ENSG00000065361 -0.15424473628738822 [1189] [1029,778,1236,1035] -3 hSpCas9 negative selection 9485866
56099715 56099738 12 + 27260156 TC32 viability CCGAGACCCACCACGGTATCTGG ERBB3 ENSG00000065361 0.13731737989204462 [385] [271,254,572,585] 2 hSpCas9 negative selection 9485867
56080361 56080384 12 + 27869803 HPAFII viability after 27 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.9006907361266647 [127] [147,106,NaN] 7 hSpCas9 negative selection 9547691
56083811 56083834 12 + 27869803 HPAFII viability after 27 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.30302193618224993 [726] [734,251,NaN] 2 hSpCas9 negative selection 9547692
56085059 56085082 12 + 27869803 HPAFII viability after 27 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.2542123455190281 [257] [134,95,NaN] -2 hSpCas9 negative selection 9547693
56087580 56087603 12 - 27869803 HPAFII viability after 27 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.45788672292580834 [498] [184,195,NaN] -3 hSpCas9 negative selection 9547694
56087860 56087883 12 + 27869803 HPAFII viability after 27 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.12437894210293504 [238] [159,77,NaN] -1 hSpCas9 negative selection 9547695
56088022 56088045 12 - 27869803 HPAFII viability after 27 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.005967896294459818 [107] [1,101,NaN] 0 hSpCas9 negative selection 9547696
56080361 56080384 12 + 27869803 HPAFII viability after 15 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.6859337319060821 [127] [298,172,NaN] 7 hSpCas9 negative selection 9630140
56083811 56083834 12 + 27869803 HPAFII viability after 15 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.24211640874517437 [726] [1008,443,NaN] -3 hSpCas9 negative selection 9630141
56085059 56085082 12 + 27869803 HPAFII viability after 15 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.12042833943403441 [257] [333,205,NaN] -1 hSpCas9 negative selection 9630142
56087580 56087603 12 - 27869803 HPAFII viability after 15 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -1.1692599737806115 [498] [354,165,NaN] -8 hSpCas9 negative selection 9630143
56087860 56087883 12 + 27869803 HPAFII viability after 15 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.14144281472164308 [238] [296,192,NaN] -2 hSpCas9 negative selection 9630144
56088022 56088045 12 - 27869803 HPAFII viability after 15 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.6417132956261962 [107] [14,50,NaN] -8 hSpCas9 negative selection 9630145
56080361 56080384 12 + 27869803 ASPC1 viability after 36 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.42861734331573115 [555] [97,69,233] -4 hSpCas9 negative selection 9712589
56083811 56083834 12 + 27869803 ASPC1 viability after 36 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.15962340787514417 [1440] [307,790,274] -2 hSpCas9 negative selection 9712590
56085059 56085082 12 + 27869803 ASPC1 viability after 36 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 -0.7362339771030619 [767] [308,76,121] -6 hSpCas9 negative selection 9712591
56087580 56087603 12 - 27869803 ASPC1 viability after 36 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 0.8415921439952012 [1101] [1057,563,522] 7 hSpCas9 negative selection 9712592
56087860 56087883 12 + 27869803 ASPC1 viability after 36 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.11596402096314681 [680] [315,65,270] -1 hSpCas9 negative selection 9712593
56088022 56088045 12 - 27869803 ASPC1 viability after 36 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.9397272859904291 [182] [21,12,56] -7 hSpCas9 negative selection 9712594
56080361 56080384 12 + 27869803 PATU8988S viability after 35 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.9909336487991929 [409] [119,45,NaN] -7 hSpCas9 negative selection 9795038
56083811 56083834 12 + 27869803 PATU8988S viability after 35 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.48204174348443074 [1357] [428,353,NaN] -5 hSpCas9 negative selection 9795039
56085059 56085082 12 + 27869803 PATU8988S viability after 35 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.20769124377955717 [684] [362,273,NaN] 2 hSpCas9 negative selection 9795040
56087580 56087603 12 - 27869803 PATU8988S viability after 35 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.9304443438830238 [1000] [225,196,NaN] -7 hSpCas9 negative selection 9795041
56087860 56087883 12 + 27869803 PATU8988S viability after 35 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.5418410562476605 [584] [90,232,NaN] -5 hSpCas9 negative selection 9795042
56088022 56088045 12 - 27869803 PATU8988S viability after 35 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -1.1550970424921587 [223] [44,35,NaN] -8 hSpCas9 negative selection 9795043
56080361 56080384 12 + 27869803 PATU8988S viability after 31 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.8604693444327256 [409] [104,70,NaN] -7 hSpCas9 negative selection 9877487
56083811 56083834 12 + 27869803 PATU8988S viability after 31 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 -0.21268845785350932 [1357] [417,529,NaN] -2 hSpCas9 negative selection 9877488
56085059 56085082 12 + 27869803 PATU8988S viability after 31 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.1282092052590758 [684] [316,274,NaN] 1 hSpCas9 negative selection 9877489
56087580 56087603 12 - 27869803 PATU8988S viability after 31 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.7576309317612516 [1000] [232,239,NaN] -7 hSpCas9 negative selection 9877490
56087860 56087883 12 + 27869803 PATU8988S viability after 31 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.053484573985092806 [584] [105,375,NaN] 0 hSpCas9 negative selection 9877491
56088022 56088045 12 - 27869803 PATU8988S viability after 31 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.716640476411917 [223] [12,106,NaN] -6 hSpCas9 negative selection 9877492
56080361 56080384 12 + 27869803 HPAFII viability after 35 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 1.2690252041673982 [127] [134,179,NaN] 8 hSpCas9 negative selection 9959936
56083811 56083834 12 + 27869803 HPAFII viability after 35 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.4794698988471986 [726] [665,340,NaN] 3 hSpCas9 negative selection 9959937
56085059 56085082 12 + 27869803 HPAFII viability after 35 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.1865813261758593 [257] [142,154,NaN] 1 hSpCas9 negative selection 9959938
56087580 56087603 12 - 27869803 HPAFII viability after 35 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.4696017030928321 [498] [220,138,NaN] -3 hSpCas9 negative selection 9959939
56087860 56087883 12 + 27869803 HPAFII viability after 35 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.8175447551808495 [238] [78,56,NaN] -5 hSpCas9 negative selection 9959940
56088022 56088045 12 - 27869803 HPAFII viability after 35 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.15878752125413387 [107] [0,102,NaN] -1 hSpCas9 negative selection 9959941
56080361 56080384 12 + 27869803 HPAFII viability after 31 days GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.8999217326858788 [127] [134,132,NaN] 6 hSpCas9 negative selection 10042385
56083811 56083834 12 + 27869803 HPAFII viability after 31 days CACTGTACAAGCTCTACGAGAGG ERBB3 ENSG00000065361 0.2874581106138252 [726] [619,364,NaN] 2 hSpCas9 negative selection 10042386
56085059 56085082 12 + 27869803 HPAFII viability after 31 days CCAACCTCCGCGTGGTGCGAGGG ERBB3 ENSG00000065361 0.004822055348530127 [257] [117,174,NaN] 0 hSpCas9 negative selection 10042387
56087580 56087603 12 - 27869803 HPAFII viability after 31 days CTTGCAAACCTCATGACAGGGGG ERBB3 ENSG00000065361 -0.39738161292307206 [498] [259,160,NaN] -3 hSpCas9 negative selection 10042388
56087860 56087883 12 + 27869803 HPAFII viability after 31 days TGCCATGATGAGTGTGCCGGGGG ERBB3 ENSG00000065361 -0.5513453500861977 [238] [80,102,NaN] -4 hSpCas9 negative selection 10042389
56088022 56088045 12 - 27869803 HPAFII viability after 31 days ACTGTCATTGAAGTGCCGGCAGG ERBB3 ENSG00000065361 -0.6792949073898413 [107] [0,77,NaN] -4 hSpCas9 negative selection 10042390
56085076 56085099 12 + 28162770 P31FUJ viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.3454965660257667 [216] [323] 4 hSpCas9 negative selection 10150943
56085144 56085167 12 - 28162770 P31FUJ viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.35436418429529204 [98] [90] -3 hSpCas9 negative selection 10150944
56080361 56080384 12 + 28162770 P31FUJ viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.10161683465618054 [45] [57] 1 hSpCas9 negative selection 10150945
56083892 56083915 12 - 28162770 P31FUJ viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -1.5864391590290792 [45] [17] -7 hSpCas9 negative selection 10150946
56083821 56083844 12 + 28162770 P31FUJ viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.2838755567403029 [136] [195] 3 hSpCas9 negative selection 10150947
56085051 56085074 12 + 28162770 P31FUJ viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.008205895089416243 [241] [285] 0 hSpCas9 negative selection 10150948
56080309 56080332 12 + 28162770 P31FUJ viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.5142964957880284 [226] [380] 6 hSpCas9 negative selection 10150949
56083784 56083807 12 - 28162770 P31FUJ viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.06806427494515432 [482] [594] 0 hSpCas9 negative selection 10150950
56085021 56085044 12 - 28162770 P31FUJ viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.654104016739985 [62] [232] 9 hSpCas9 negative selection 10150951
56085134 56085157 12 - 28162770 P31FUJ viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.027962027794588007 [105] [126] 0 hSpCas9 negative selection 10150952
56085076 56085099 12 + 28162770 TF1 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 NaN [NaN] [202] 1 hSpCas9 negative selection 10320309
56085144 56085167 12 - 28162770 TF1 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 NaN [NaN] [68] 1 hSpCas9 negative selection 10320310
56080361 56080384 12 + 28162770 TF1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 NaN [NaN] [9] 1 hSpCas9 negative selection 10320311
56083892 56083915 12 - 28162770 TF1 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 NaN [NaN] [14] 1 hSpCas9 negative selection 10320312
56083821 56083844 12 + 28162770 TF1 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 NaN [NaN] [120] 1 hSpCas9 negative selection 10320313
56085051 56085074 12 + 28162770 TF1 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 NaN [NaN] [77] 1 hSpCas9 negative selection 10320314
56080309 56080332 12 + 28162770 TF1 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 NaN [NaN] [218] 1 hSpCas9 negative selection 10320315
56083784 56083807 12 - 28162770 TF1 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 NaN [NaN] [355] 1 hSpCas9 negative selection 10320316
56085021 56085044 12 - 28162770 TF1 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 NaN [NaN] [65] 1 hSpCas9 negative selection 10320317
56085134 56085157 12 - 28162770 TF1 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 NaN [NaN] [73] 1 hSpCas9 negative selection 10320318
56085076 56085099 12 + 28162770 SKM1 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.11958161575267262 [62] [120] 1 hSpCas9 negative selection 10489675
56085144 56085167 12 - 28162770 SKM1 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.1375035237499349 [27] [44] -1 hSpCas9 negative selection 10489676
56080361 56080384 12 + 28162770 SKM1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.302627538928426 [29] [42] -3 hSpCas9 negative selection 10489677
56083892 56083915 12 - 28162770 SKM1 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.8024891668857883 [11] [36] 7 hSpCas9 negative selection 10489678
56083821 56083844 12 + 28162770 SKM1 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.7498519122661701 [38] [40] -5 hSpCas9 negative selection 10489679
56085051 56085074 12 + 28162770 SKM1 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.7239666710832869 [49] [145] 7 hSpCas9 negative selection 10489680
56080309 56080332 12 + 28162770 SKM1 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.39700808391979026 [60] [141] 4 hSpCas9 negative selection 10489681
56083784 56083807 12 - 28162770 SKM1 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.009280266214586108 [114] [201] 0 hSpCas9 negative selection 10489682
56085021 56085044 12 - 28162770 SKM1 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.2483876298693926 [14] [62] 9 hSpCas9 negative selection 10489683
56085134 56085157 12 - 28162770 SKM1 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -0.5906761519155499 [22] [26] -5 hSpCas9 negative selection 10489684
56085076 56085099 12 + 28162770 SKM1 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.11958161575267262 [62] [120] 1 hSpCas9 negative selection 10659041
56085144 56085167 12 - 28162770 SKM1 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.1375035237499349 [27] [44] -1 hSpCas9 negative selection 10659042
56080361 56080384 12 + 28162770 SKM1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.302627538928426 [29] [42] -3 hSpCas9 negative selection 10659043
56083892 56083915 12 - 28162770 SKM1 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.8024891668857883 [11] [36] 7 hSpCas9 negative selection 10659044
56083821 56083844 12 + 28162770 SKM1 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.7498519122661701 [38] [40] -5 hSpCas9 negative selection 10659045
56085051 56085074 12 + 28162770 SKM1 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.7239666710832869 [49] [145] 7 hSpCas9 negative selection 10659046
56080309 56080332 12 + 28162770 SKM1 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.39700808391979026 [60] [141] 4 hSpCas9 negative selection 10659047
56083784 56083807 12 - 28162770 SKM1 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.009280266214586108 [114] [201] 0 hSpCas9 negative selection 10659048
56085021 56085044 12 - 28162770 SKM1 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.2483876298693926 [14] [62] 9 hSpCas9 negative selection 10659049
56085134 56085157 12 - 28162770 SKM1 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -0.5906761519155499 [22] [26] -5 hSpCas9 negative selection 10659050
56085076 56085099 12 + 28162770 PL21 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.3296503474857244 [180] [98] 3 hSpCas9 negative selection 10828407
56085144 56085167 12 - 28162770 PL21 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -2.1217884803980427 [89] [8] -8 hSpCas9 negative selection 10828408
56080361 56080384 12 + 28162770 PL21 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 1.3111709268780642 [99] [107] 9 hSpCas9 negative selection 10828409
56083892 56083915 12 - 28162770 PL21 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 2.20013961448932 [41] [83] 9 hSpCas9 negative selection 10828410
56083821 56083844 12 + 28162770 PL21 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.9820637167314291 [176] [38] -6 hSpCas9 negative selection 10828411
56085051 56085074 12 + 28162770 PL21 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.0007730794366760038 [199] [86] 0 hSpCas9 negative selection 10828412
56080309 56080332 12 + 28162770 PL21 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 1.0116945250762095 [195] [171] 8 hSpCas9 negative selection 10828413
56083784 56083807 12 - 28162770 PL21 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.937363909260615 [351] [79] -6 hSpCas9 negative selection 10828414
56085021 56085044 12 - 28162770 PL21 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.2716928755143544 [58] [30] 2 hSpCas9 negative selection 10828415
56085134 56085157 12 - 28162770 PL21 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -1.7796825035730497 [70] [8] -8 hSpCas9 negative selection 10828416
56085076 56085099 12 + 28162770 P31FUJ viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.3454965660257667 [216] [323] 4 hSpCas9 negative selection 10997773
56085144 56085167 12 - 28162770 P31FUJ viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.35436418429529204 [98] [90] -3 hSpCas9 negative selection 10997774
56080361 56080384 12 + 28162770 P31FUJ viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.10161683465618054 [45] [57] 1 hSpCas9 negative selection 10997775
56083892 56083915 12 - 28162770 P31FUJ viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -1.5864391590290792 [45] [17] -7 hSpCas9 negative selection 10997776
56083821 56083844 12 + 28162770 P31FUJ viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.2838755567403029 [136] [195] 3 hSpCas9 negative selection 10997777
56085051 56085074 12 + 28162770 P31FUJ viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.008205895089416243 [241] [285] 0 hSpCas9 negative selection 10997778
56080309 56080332 12 + 28162770 P31FUJ viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.5142964957880284 [226] [380] 6 hSpCas9 negative selection 10997779
56083784 56083807 12 - 28162770 P31FUJ viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.06806427494515432 [482] [594] 0 hSpCas9 negative selection 10997780
56085021 56085044 12 - 28162770 P31FUJ viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.654104016739985 [62] [232] 9 hSpCas9 negative selection 10997781
56085134 56085157 12 - 28162770 P31FUJ viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.027962027794588007 [105] [126] 0 hSpCas9 negative selection 10997782
56085076 56085099 12 + 28162770 OCIAML5 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.370325850472451 [116] [272] 3 hSpCas9 negative selection 11167139
56085144 56085167 12 - 28162770 OCIAML5 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 1.6073650477733001 [25] [142] 9 hSpCas9 negative selection 11167140
56080361 56080384 12 + 28162770 OCIAML5 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.18766960264843613 [52] [83] -1 hSpCas9 negative selection 11167141
56083892 56083915 12 - 28162770 OCIAML5 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -0.1415731880589819 [21] [35] -1 hSpCas9 negative selection 11167142
56083821 56083844 12 + 28162770 OCIAML5 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 1.0429638695344605 [56] [211] 8 hSpCas9 negative selection 11167143
56085051 56085074 12 + 28162770 OCIAML5 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.2671040701428409 [73] [110] -2 hSpCas9 negative selection 11167144
56080309 56080332 12 + 28162770 OCIAML5 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 1.0680801214467883 [129] [491] 8 hSpCas9 negative selection 11167145
56083784 56083807 12 - 28162770 OCIAML5 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.5312620686875087 [183] [479] 4 hSpCas9 negative selection 11167146
56085021 56085044 12 - 28162770 OCIAML5 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.2548486330525148 [38] [83] 2 hSpCas9 negative selection 11167147
56085134 56085157 12 - 28162770 OCIAML5 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 1.346203056272277 [55] [256] 9 hSpCas9 negative selection 11167148
56085076 56085099 12 + 28162770 EOL1 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.4472259940373481 [425] [305] 4 hSpCas9 negative selection 11336505
56085144 56085167 12 - 28162770 EOL1 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.5067915400374099 [88] [32] -4 hSpCas9 negative selection 11336506
56080361 56080384 12 + 28162770 EOL1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.4025950683751789 [111] [77] 3 hSpCas9 negative selection 11336507
56083892 56083915 12 - 28162770 EOL1 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -0.32543048143781306 [87] [36] -2 hSpCas9 negative selection 11336508
56083821 56083844 12 + 28162770 EOL1 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.11147919831853675 [252] [143] 1 hSpCas9 negative selection 11336509
56085051 56085074 12 + 28162770 EOL1 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.4553002992460091 [431] [165] -3 hSpCas9 negative selection 11336510
56080309 56080332 12 + 28162770 EOL1 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.8365716843044485 [260] [76] -5 hSpCas9 negative selection 11336511
56083784 56083807 12 - 28162770 EOL1 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.5610947698566237 [466] [362] 5 hSpCas9 negative selection 11336512
56085021 56085044 12 - 28162770 EOL1 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 3.4245499382445215 [101] [576] 9 hSpCas9 negative selection 11336513
56085134 56085157 12 - 28162770 EOL1 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.6563516606209617 [111] [92] 6 hSpCas9 negative selection 11336514
56085076 56085099 12 + 28162770 MOLM13 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.7036608326822266 [275] [324] 5 hSpCas9 negative selection 11505871
56085144 56085167 12 - 28162770 MOLM13 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -1.3394655405130256 [125] [35] -6 hSpCas9 negative selection 11505872
56080361 56080384 12 + 28162770 MOLM13 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 1.3747799771530973 [103] [194] 9 hSpCas9 negative selection 11505873
56083892 56083915 12 - 28162770 MOLM13 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 1.4807134219021625 [55] [112] 9 hSpCas9 negative selection 11505874
56083821 56083844 12 + 28162770 MOLM13 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.012694755793752344 [169] [123] 0 hSpCas9 negative selection 11505875
56085051 56085074 12 + 28162770 MOLM13 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 1.1328512043309547 [303] [481] 8 hSpCas9 negative selection 11505876
56080309 56080332 12 + 28162770 MOLM13 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.9303046075708505 [368] [139] -5 hSpCas9 negative selection 11505877
56083784 56083807 12 - 28162770 MOLM13 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.054747117401419465 [486] [338] 0 hSpCas9 negative selection 11505878
56085021 56085044 12 - 28162770 MOLM13 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.29593669875528383 [88] [78] 2 hSpCas9 negative selection 11505879
56085134 56085157 12 - 28162770 MOLM13 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.778590221008687 [128] [159] 6 hSpCas9 negative selection 11505880
56085076 56085099 12 + 28162770 HEL viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.19022662730285034 [259] [189] 1 hSpCas9 negative selection 11675237
56085144 56085167 12 - 28162770 HEL viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 1.0313041199180097 [109] [143] 8 hSpCas9 negative selection 11675238
56080361 56080384 12 + 28162770 HEL viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 0.420346410663909 [83] [71] 3 hSpCas9 negative selection 11675239
56083892 56083915 12 - 28162770 HEL viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -0.49476469174957804 [32] [14] -3 hSpCas9 negative selection 11675240
56083821 56083844 12 + 28162770 HEL viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.37374929078821206 [175] [86] -3 hSpCas9 negative selection 11675241
56085051 56085074 12 + 28162770 HEL viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.6427388320003571 [282] [282] 5 hSpCas9 negative selection 11675242
56080309 56080332 12 + 28162770 HEL viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.5058576600014436 [234] [105] -3 hSpCas9 negative selection 11675243
56083784 56083807 12 - 28162770 HEL viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.68283703990215 [395] [157] -4 hSpCas9 negative selection 11675244
56085021 56085044 12 - 28162770 HEL viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 -0.4727383854195788 [77] [35] -3 hSpCas9 negative selection 11675245
56085134 56085157 12 - 28162770 HEL viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.7389541472596598 [86] [92] 6 hSpCas9 negative selection 11675246
56085076 56085099 12 + 28162770 MV411 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.30101859098761957 [184] [191] 2 hSpCas9 negative selection 11844603
56085144 56085167 12 - 28162770 MV411 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.48126042739983044 [57] [34] -4 hSpCas9 negative selection 11844604
56080361 56080384 12 + 28162770 MV411 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -2.4750284736883157 [131] [19] -8 hSpCas9 negative selection 11844605
56083892 56083915 12 - 28162770 MV411 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.806864959396794 [18] [27] 7 hSpCas9 negative selection 11844606
56083821 56083844 12 + 28162770 MV411 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 -0.8241157102422587 [123] [58] -5 hSpCas9 negative selection 11844607
56085051 56085074 12 + 28162770 MV411 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.5187165109109781 [232] [136] -4 hSpCas9 negative selection 11844608
56080309 56080332 12 + 28162770 MV411 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.031278477283288225 [221] [182] 0 hSpCas9 negative selection 11844609
56083784 56083807 12 - 28162770 MV411 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.10403481971860229 [332] [260] -1 hSpCas9 negative selection 11844610
56085021 56085044 12 - 28162770 MV411 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.613759765028591 [63] [164] 9 hSpCas9 negative selection 11844611
56085134 56085157 12 - 28162770 MV411 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -0.5180971955802021 [50] [29] -4 hSpCas9 negative selection 11844612
56085076 56085099 12 + 28162770 MONOMAC1 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.743665969256674 [148] [285] 7 hSpCas9 negative selection 12013969
56085144 56085167 12 - 28162770 MONOMAC1 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 -0.01646460141773276 [59] [67] 0 hSpCas9 negative selection 12013970
56080361 56080384 12 + 28162770 MONOMAC1 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.8815350213316242 [44] [27] -6 hSpCas9 negative selection 12013971
56083892 56083915 12 - 28162770 MONOMAC1 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 -0.5690056244465116 [21] [16] -5 hSpCas9 negative selection 12013972
56083821 56083844 12 + 28162770 MONOMAC1 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.1355384920273171 [107] [135] 1 hSpCas9 negative selection 12013973
56085051 56085074 12 + 28162770 MONOMAC1 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 0.7437239495657704 [86] [166] 7 hSpCas9 negative selection 12013974
56080309 56080332 12 + 28162770 MONOMAC1 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.46761454229076227 [134] [213] 4 hSpCas9 negative selection 12013975
56083784 56083807 12 - 28162770 MONOMAC1 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.04336136233121035 [181] [214] 0 hSpCas9 negative selection 12013976
56085021 56085044 12 - 28162770 MONOMAC1 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.9072998127551818 [39] [85] 8 hSpCas9 negative selection 12013977
56085134 56085157 12 - 28162770 MONOMAC1 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.6554059645265886 [35] [64] 6 hSpCas9 negative selection 12013978
56085076 56085099 12 + 28162770 OCIAML2 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 0.932494352493182 [37] [401] 8 hSpCas9 negative selection 12183335
56085144 56085167 12 - 28162770 OCIAML2 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 2.0348982079845896 [6] [158] 9 hSpCas9 negative selection 12183336
56080361 56080384 12 + 28162770 OCIAML2 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -0.4181624053480259 [26] [111] -3 hSpCas9 negative selection 12183337
56083892 56083915 12 - 28162770 OCIAML2 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 0.49284429873272484 [9] [77] 5 hSpCas9 negative selection 12183338
56083821 56083844 12 + 28162770 OCIAML2 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 0.4324084448707507 [24] [186] 4 hSpCas9 negative selection 12183339
56085051 56085074 12 + 28162770 OCIAML2 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.5989539222177006 [46] [171] -4 hSpCas9 negative selection 12183340
56080309 56080332 12 + 28162770 OCIAML2 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 -0.5425227437239467 [35] [136] -4 hSpCas9 negative selection 12183341
56083784 56083807 12 - 28162770 OCIAML2 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 0.5147530786856566 [61] [490] 5 hSpCas9 negative selection 12183342
56085021 56085044 12 - 28162770 OCIAML2 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 1.488728190260493 [8] [139] 9 hSpCas9 negative selection 12183343
56085134 56085157 12 - 28162770 OCIAML2 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 -0.6543417784145492 [22] [80] -5 hSpCas9 negative selection 12183344
56085076 56085099 12 + 28162770 OCIAML3 viability CGAGGGACCCAGGTCTACGATGG ERBB3 ENSG00000065361 -0.0014319554931317424 [62] [189] 0 hSpCas9 negative selection 12352701
56085144 56085167 12 - 28162770 OCIAML3 viability AGCGGAGCTGGCGCAGAGCGTGG ERBB3 ENSG00000065361 0.7001754640802949 [20] [102] 6 hSpCas9 negative selection 12352702
56080361 56080384 12 + 28162770 OCIAML3 viability GAGGTGGGCAACTCTCAGGCAGG ERBB3 ENSG00000065361 -1.1789701410453193 [23] [31] -7 hSpCas9 negative selection 12352703
56083892 56083915 12 - 28162770 OCIAML3 viability GGGCTCACTAACCTGCAGGAAGG ERBB3 ENSG00000065361 1.7483845571229146 [6] [70] 9 hSpCas9 negative selection 12352704
56083821 56083844 12 + 28162770 OCIAML3 viability GCTCTACGAGAGGTGTGAGGTGG ERBB3 ENSG00000065361 1.6460434475087915 [28] [273] 9 hSpCas9 negative selection 12352705
56085051 56085074 12 + 28162770 OCIAML3 viability ACCATTGCCCAACCTCCGCGTGG ERBB3 ENSG00000065361 -0.2850573994350107 [66] [165] -2 hSpCas9 negative selection 12352706
56080309 56080332 12 + 28162770 OCIAML3 viability GAACGACGCTCTGCAGGTGCTGG ERBB3 ENSG00000065361 0.23953121353709605 [38] [138] 2 hSpCas9 negative selection 12352707
56083784 56083807 12 - 28162770 OCIAML3 viability GTATTGGTTCTCAGCATCGCCGG ERBB3 ENSG00000065361 -0.9015804422344557 [124] [201] -6 hSpCas9 negative selection 12352708
56085021 56085044 12 - 28162770 OCIAML3 viability AGAATTCATTCATGGCCACGAGG ERBB3 ENSG00000065361 0.4486366970843305 [24] [102] 4 hSpCas9 negative selection 12352709
56085134 56085157 12 - 28162770 OCIAML3 viability GCGCAGAGCGTGGCTGGAGTTGG ERBB3 ENSG00000065361 0.018969236566589776 [33] [103] 0 hSpCas9 negative selection 12352710