Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2101
• Symbol: ESRRA
• Description: estrogen related receptor alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/ESRRA

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64314266	64314289	11	+	26472758	Jiyoye	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-1.7892218312976298	[54]	[11]	-8	hSpCas9	negative selection	51903
64307263	64307286	11	+	26472758	Jiyoye	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-2.0285215883390633	[210]	[38]	-8	hSpCas9	negative selection	51904
64314276	64314299	11	+	26472758	Jiyoye	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.8898063562512579	[85]	[34]	-6	hSpCas9	negative selection	51905
64307292	64307315	11	-	26472758	Jiyoye	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.4293258862112475	[149]	[20]	-8	hSpCas9	negative selection	51906
64314045	64314068	11	+	26472758	Jiyoye	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.2816444994220145	[95]	[87]	2	hSpCas9	negative selection	51907
64314797	64314820	11	+	26472758	Jiyoye	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.027586718231319335	[133]	[102]	0	hSpCas9	negative selection	51908
64307307	64307330	11	-	26472758	Jiyoye	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.4741801219955075	[69]	[37]	-3	hSpCas9	negative selection	51909
64314813	64314836	11	-	26472758	Jiyoye	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.745977294957632	[33]	[42]	5	hSpCas9	negative selection	51910
64315181	64315204	11	+	26472758	Jiyoye	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.6434506915640944	[115]	[55]	-4	hSpCas9	negative selection	51911
64315256	64315279	11	-	26472758	Jiyoye	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.44507099805043465	[203]	[112]	-3	hSpCas9	negative selection	51912
64314266	64314289	11	+	26472758	KBM7	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	0.1558326937291501	[161,125]	[77,71]	1	hSpCas9	negative selection	243021
64307263	64307286	11	+	26472758	KBM7	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.1543579776938528	[719,574]	[266,275]	-1	hSpCas9	negative selection	243022
64314276	64314299	11	+	26472758	KBM7	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.278241772203524	[194,184]	[95,53]	-3	hSpCas9	negative selection	243023
64307292	64307315	11	-	26472758	KBM7	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.269103596843756	[441,332]	[29,114]	-7	hSpCas9	negative selection	243024
64314045	64314068	11	+	26472758	KBM7	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.49980194325586486	[545,294]	[330,219]	5	hSpCas9	negative selection	243025
64314797	64314820	11	+	26472758	KBM7	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.3565194771141884	[1036,705]	[516,516]	4	hSpCas9	negative selection	243026
64307307	64307330	11	-	26472758	KBM7	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-1.0895411859103563	[345,455]	[103,77]	-7	hSpCas9	negative selection	243027
64314813	64314836	11	-	26472758	KBM7	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	1.5575472554107483	[143,143]	[232,170]	9	hSpCas9	negative selection	243028
64315181	64315204	11	+	26472758	KBM7	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.00414046633331111	[677,510]	[217,327]	0	hSpCas9	negative selection	243029
64315256	64315279	11	-	26472758	KBM7	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.6042650466029899	[608,880]	[581,511]	6	hSpCas9	negative selection	243030
64314266	64314289	11	+	26472758	Raji	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-2.062541466068713	[107]	[5]	-8	hSpCas9	negative selection	434139
64307263	64307286	11	+	26472758	Raji	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-1.0091603697406895	[450]	[51]	-6	hSpCas9	negative selection	434140
64314276	64314299	11	+	26472758	Raji	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.12394201073285638	[107]	[22]	-1	hSpCas9	negative selection	434141
64307292	64307315	11	-	26472758	Raji	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.1354729885225643	[141]	[14]	-7	hSpCas9	negative selection	434142
64314045	64314068	11	+	26472758	Raji	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.6479519167363024	[120]	[87]	9	hSpCas9	negative selection	434143
64314797	64314820	11	+	26472758	Raji	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.3911765013741906	[390]	[118]	4	hSpCas9	negative selection	434144
64307307	64307330	11	-	26472758	Raji	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.7339187186073424	[128]	[17]	-5	hSpCas9	negative selection	434145
64314813	64314836	11	-	26472758	Raji	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.8717552868804573	[72]	[30]	7	hSpCas9	negative selection	434146
64315181	64315204	11	+	26472758	Raji	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.11189901649609252	[318]	[79]	1	hSpCas9	negative selection	434147
64315256	64315279	11	-	26472758	Raji	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.24824607121344927	[311]	[85]	2	hSpCas9	negative selection	434148
64314266	64314289	11	+	26472758	K562	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-1.1217091711314506	[115]	[44]	-6	hSpCas9	negative selection	625257
64307263	64307286	11	+	26472758	K562	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-3.0116214315644583	[534]	[55]	-8	hSpCas9	negative selection	625258
64314276	64314299	11	+	26472758	K562	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-3.4560209904746455	[233]	[17]	-8	hSpCas9	negative selection	625259
64307292	64307315	11	-	26472758	K562	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.885539866458221	[266]	[60]	-7	hSpCas9	negative selection	625260
64314045	64314068	11	+	26472758	K562	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.026728323954666566	[320]	[265]	0	hSpCas9	negative selection	625261
64314797	64314820	11	+	26472758	K562	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.48604822920101753	[442]	[266]	-3	hSpCas9	negative selection	625262
64307307	64307330	11	-	26472758	K562	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.4185462850559825	[246]	[38]	-8	hSpCas9	negative selection	625263
64314813	64314836	11	-	26472758	K562	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-0.36284244016348377	[162]	[106]	-2	hSpCas9	negative selection	625264
64315181	64315204	11	+	26472758	K562	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.05733317506595148	[517]	[454]	0	hSpCas9	negative selection	625265
64315256	64315279	11	-	26472758	K562	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.40215411849590943	[597]	[381]	-3	hSpCas9	negative selection	625266
64314045	64314068	11	+	26627737	DLD1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	779887
64314270	64314293	11	+	26627737	DLD1	viability	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.8889828451200859	[165]	[117,123,53]	8	hSpCas9	negative selection	779888
64314273	64314296	11	+	26627737	DLD1	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	1.0743559854944729	[141]	[125,123,39]	8	hSpCas9	negative selection	779889
64314354	64314377	11	-	26627737	DLD1	viability	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.9565899242466236	[816]	[131,149,115]	-7	hSpCas9	negative selection	779890
64315256	64315279	11	-	26627737	DLD1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.35965616048377935	[622]	[197,84,166]	-4	hSpCas9	negative selection	779891
64315257	64315280	11	-	26627737	DLD1	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.6180747304396412	[2264]	[295,653,444]	-6	hSpCas9	negative selection	779892
64314045	64314068	11	+	26627737	GBM cells	viability after 5 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	862202
64314270	64314293	11	+	26627737	GBM cells	viability after 5 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.16837454987891232	[111]	[30,103]	2	hSpCas9	negative selection	862203
64314273	64314296	11	+	26627737	GBM cells	viability after 5 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.21150410519371177	[123]	[93,59]	3	hSpCas9	negative selection	862204
64314354	64314377	11	-	26627737	GBM cells	viability after 5 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.4560430203891477	[242]	[85,103]	-6	hSpCas9	negative selection	862205
64315256	64315279	11	-	26627737	GBM cells	viability after 5 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.2438519478195481	[310]	[198,195]	4	hSpCas9	negative selection	862206
64315257	64315280	11	-	26627737	GBM cells	viability after 5 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.1657398598818538	[949]	[610,531]	2	hSpCas9	negative selection	862207
64314045	64314068	11	+	26627737	GBM cells	viability after 13 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	944517
64314270	64314293	11	+	26627737	GBM cells	viability after 13 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.09531968793205503	[111]	[38,85]	1	hSpCas9	negative selection	944518
64314273	64314296	11	+	26627737	GBM cells	viability after 13 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.09801606952862407	[123]	[58,65]	-1	hSpCas9	negative selection	944519
64314354	64314377	11	-	26627737	GBM cells	viability after 13 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.3760154354777308	[242]	[121,84]	-4	hSpCas9	negative selection	944520
64315256	64315279	11	-	26627737	GBM cells	viability after 13 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.07163234814314051	[310]	[146,201]	0	hSpCas9	negative selection	944521
64315257	64315280	11	-	26627737	GBM cells	viability after 13 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.31474818396565607	[949]	[730,567]	4	hSpCas9	negative selection	944522
64314045	64314068	11	+	26627737	GBM cells	viability after 21 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1026832
64314270	64314293	11	+	26627737	GBM cells	viability after 21 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.44714507453144947	[111]	[83,81]	4	hSpCas9	negative selection	1026833
64314273	64314296	11	+	26627737	GBM cells	viability after 21 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.8112588252762925	[123]	[124,111]	7	hSpCas9	negative selection	1026834
64314354	64314377	11	-	26627737	GBM cells	viability after 21 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.20635574552234012	[242]	[127,101]	-2	hSpCas9	negative selection	1026835
64315256	64315279	11	-	26627737	GBM cells	viability after 21 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.6715588228633618	[310]	[115,96]	-5	hSpCas9	negative selection	1026836
64315257	64315280	11	-	26627737	GBM cells	viability after 21 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5428892254453401	[949]	[788,717]	5	hSpCas9	negative selection	1026837
64314045	64314068	11	+	26627737	RPE1	viability after 9 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1109147
64314270	64314293	11	+	26627737	RPE1	viability after 9 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-1.278269434249588	[644]	[146,0]	-7	hSpCas9	negative selection	1109148
64314273	64314296	11	+	26627737	RPE1	viability after 9 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	2.886223780517841	[67]	[166,144]	9	hSpCas9	negative selection	1109149
64314354	64314377	11	-	26627737	RPE1	viability after 9 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.07721924896720025	[978]	[238,356]	0	hSpCas9	negative selection	1109150
64315256	64315279	11	-	26627737	RPE1	viability after 9 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.26465773783620783	[623]	[173,312]	2	hSpCas9	negative selection	1109151
64315257	64315280	11	-	26627737	RPE1	viability after 9 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.20158461994128896	[3486]	[1443,1011]	1	hSpCas9	negative selection	1109152
64314045	64314068	11	+	26627737	RPE1	viability after 12 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1191462
64314270	64314293	11	+	26627737	RPE1	viability after 12 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-2.3339060284063686	[644]	[46,20]	-9	hSpCas9	negative selection	1191463
64314273	64314296	11	+	26627737	RPE1	viability after 12 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	2.9072822776793203	[67]	[189,80]	9	hSpCas9	negative selection	1191464
64314354	64314377	11	-	26627737	RPE1	viability after 12 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.22106500241517513	[978]	[230,219]	-1	hSpCas9	negative selection	1191465
64315256	64315279	11	-	26627737	RPE1	viability after 12 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.14698416571233816	[623]	[172,198]	1	hSpCas9	negative selection	1191466
64315257	64315280	11	-	26627737	RPE1	viability after 12 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.20778745023290757	[3486]	[1403,740]	1	hSpCas9	negative selection	1191467
64314045	64314068	11	+	26627737	RPE1	viability after 15 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1273777
64314270	64314293	11	+	26627737	RPE1	viability after 15 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-1.6913430590372824	[644]	[112,1]	-8	hSpCas9	negative selection	1273778
64314273	64314296	11	+	26627737	RPE1	viability after 15 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	3.592520248140561	[67]	[285,179]	9	hSpCas9	negative selection	1273779
64314354	64314377	11	-	26627737	RPE1	viability after 15 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	0.18035193492767504	[978]	[267,357]	1	hSpCas9	negative selection	1273780
64315256	64315279	11	-	26627737	RPE1	viability after 15 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.004555584790657263	[623]	[121,227]	0	hSpCas9	negative selection	1273781
64315257	64315280	11	-	26627737	RPE1	viability after 15 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.20164648529620566	[3486]	[1366,909]	1	hSpCas9	negative selection	1273782
64314045	64314068	11	+	26627737	RPE1	viability after 18 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1356092
64314270	64314293	11	+	26627737	RPE1	viability after 18 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-0.9847549224100982	[644]	[144,26]	-6	hSpCas9	negative selection	1356093
64314273	64314296	11	+	26627737	RPE1	viability after 18 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	2.711600891648795	[67]	[169,66]	9	hSpCas9	negative selection	1356094
64314354	64314377	11	-	26627737	RPE1	viability after 18 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	0.15429183325380302	[978]	[352,230]	1	hSpCas9	negative selection	1356095
64315256	64315279	11	-	26627737	RPE1	viability after 18 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.7774006514719138	[623]	[119,74]	-5	hSpCas9	negative selection	1356096
64315257	64315280	11	-	26627737	RPE1	viability after 18 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.0421940163694603	[3486]	[1098,829]	0	hSpCas9	negative selection	1356097
64314045	64314068	11	+	26627737	HeLa	viability after 8 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1438407
64314270	64314293	11	+	26627737	HeLa	viability after 8 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.33344174247316705	[148]	[132,50,72]	3	hSpCas9	negative selection	1438408
64314273	64314296	11	+	26627737	HeLa	viability after 8 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.8059220136266065	[300]	[65,84,71]	-7	hSpCas9	negative selection	1438409
64314354	64314377	11	-	26627737	HeLa	viability after 8 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-1.2743110614888153	[411]	[4,125,75]	-8	hSpCas9	negative selection	1438410
64315256	64315279	11	-	26627737	HeLa	viability after 8 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.48877232804236287	[771]	[261,189,268]	-5	hSpCas9	negative selection	1438411
64315257	64315280	11	-	26627737	HeLa	viability after 8 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.7581439571652873	[1014]	[798,818,641]	6	hSpCas9	negative selection	1438412
64314045	64314068	11	+	26627737	HeLa	viability after 12 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1520722
64314270	64314293	11	+	26627737	HeLa	viability after 12 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.7668962171491729	[148]	[80,91,141]	6	hSpCas9	negative selection	1520723
64314273	64314296	11	+	26627737	HeLa	viability after 12 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-1.0797438131833834	[300]	[1,123,41]	-7	hSpCas9	negative selection	1520724
64314354	64314377	11	-	26627737	HeLa	viability after 12 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.7211920299475624	[411]	[140,64,108]	-6	hSpCas9	negative selection	1520725
64315256	64315279	11	-	26627737	HeLa	viability after 12 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-1.5052166868026513	[771]	[58,155,115]	-8	hSpCas9	negative selection	1520726
64315257	64315280	11	-	26627737	HeLa	viability after 12 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5985391249297578	[1014]	[629,769,490]	5	hSpCas9	negative selection	1520727
64314045	64314068	11	+	26627737	HeLa	viability after 15 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1603037
64314270	64314293	11	+	26627737	HeLa	viability after 15 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.7870142298106132	[148]	[152,23,138]	6	hSpCas9	negative selection	1603038
64314273	64314296	11	+	26627737	HeLa	viability after 15 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.619767765701559	[300]	[15,144,78]	-5	hSpCas9	negative selection	1603039
64314354	64314377	11	-	26627737	HeLa	viability after 15 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-2.020524610383402	[411]	[11,99,9]	-9	hSpCas9	negative selection	1603040
64315256	64315279	11	-	26627737	HeLa	viability after 15 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.9455717818422132	[771]	[186,141,159]	-7	hSpCas9	negative selection	1603041
64315257	64315280	11	-	26627737	HeLa	viability after 15 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.7660924960195852	[1014]	[575,683,861]	6	hSpCas9	negative selection	1603042
64314045	64314068	11	+	26627737	HeLa	viability after 18 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1685352
64314270	64314293	11	+	26627737	HeLa	viability after 18 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.7601486786211676	[148]	[97,20,138]	6	hSpCas9	negative selection	1685353
64314273	64314296	11	+	26627737	HeLa	viability after 18 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.6140724422959103	[300]	[8,122,78]	-5	hSpCas9	negative selection	1685354
64314354	64314377	11	-	26627737	HeLa	viability after 18 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-2.040280950742582	[411]	[9,78,9]	-9	hSpCas9	negative selection	1685355
64315256	64315279	11	-	26627737	HeLa	viability after 18 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.9461839652662875	[771]	[128,112,159]	-7	hSpCas9	negative selection	1685356
64315257	64315280	11	-	26627737	HeLa	viability after 18 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.7692838202117198	[1014]	[392,561,861]	6	hSpCas9	negative selection	1685357
64314045	64314068	11	+	26627737	HCT116	viability after 6 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1767667
64314270	64314293	11	+	26627737	HCT116	viability after 6 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.8868106234825535	[312]	[41,117]	5	hSpCas9	negative selection	1767668
64314273	64314296	11	+	26627737	HCT116	viability after 6 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	4.75318216143768	[57]	[475,118]	9	hSpCas9	negative selection	1767669
64314354	64314377	11	-	26627737	HCT116	viability after 6 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	1.770821431318995	[693]	[662,211]	8	hSpCas9	negative selection	1767670
64315256	64315279	11	-	26627737	HCT116	viability after 6 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.38956179194193924	[612]	[278,41]	2	hSpCas9	negative selection	1767671
64315257	64315280	11	-	26627737	HCT116	viability after 6 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.40915822418935166	[1862]	[638,250]	2	hSpCas9	negative selection	1767672
64314045	64314068	11	+	26627737	HCT116	viability after 8 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1849982
64314270	64314293	11	+	26627737	HCT116	viability after 8 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	2.028397422105832	[54]	[158,126,85]	9	hSpCas9	negative selection	1849983
64314273	64314296	11	+	26627737	HCT116	viability after 8 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.2243090189035432	[218]	[164,42,102]	-3	hSpCas9	negative selection	1849984
64314354	64314377	11	-	26627737	HCT116	viability after 8 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.8744621998490533	[329]	[80,97,117]	-8	hSpCas9	negative selection	1849985
64315256	64315279	11	-	26627737	HCT116	viability after 8 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.07860418520328658	[375]	[188,246,152]	-1	hSpCas9	negative selection	1849986
64315257	64315280	11	-	26627737	HCT116	viability after 8 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.10371877911268745	[1053]	[638,423,559]	-1	hSpCas9	negative selection	1849987
64314045	64314068	11	+	26627737	HCT116	viability after 9 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1932297
64314270	64314293	11	+	26627737	HCT116	viability after 9 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.4958505971648048	[312]	[247,14]	3	hSpCas9	negative selection	1932298
64314273	64314296	11	+	26627737	HCT116	viability after 9 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.36763660003750065	[57]	[43,0]	2	hSpCas9	negative selection	1932299
64314354	64314377	11	-	26627737	HCT116	viability after 9 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-1.7736290558972607	[693]	[37,66]	-8	hSpCas9	negative selection	1932300
64315256	64315279	11	-	26627737	HCT116	viability after 9 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.722511441214128	[612]	[82,111]	-5	hSpCas9	negative selection	1932301
64315257	64315280	11	-	26627737	HCT116	viability after 9 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.3863335898242819	[1862]	[466,794]	3	hSpCas9	negative selection	1932302
64314045	64314068	11	+	26627737	HCT116	viability after 12 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2014612
64314270	64314293	11	+	26627737	HCT116	viability after 12 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	2.027978992962925	[54]	[150,128,70]	9	hSpCas9	negative selection	2014613
64314273	64314296	11	+	26627737	HCT116	viability after 12 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.9790244333837641	[218]	[45,47,81]	-8	hSpCas9	negative selection	2014614
64314354	64314377	11	-	26627737	HCT116	viability after 12 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.7849260620203062	[329]	[92,115,93]	-7	hSpCas9	negative selection	2014615
64315256	64315279	11	-	26627737	HCT116	viability after 12 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.25184279969704637	[375]	[115,238,148]	-3	hSpCas9	negative selection	2014616
64315257	64315280	11	-	26627737	HCT116	viability after 12 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.18823261171908912	[1053]	[636,639,615]	2	hSpCas9	negative selection	2014617
64314045	64314068	11	+	26627737	HCT116	viability after 15 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2096927
64314270	64314293	11	+	26627737	HCT116	viability after 15 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	2.370304994091387	[54]	[306,83,116]	9	hSpCas9	negative selection	2096928
64314273	64314296	11	+	26627737	HCT116	viability after 15 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.6760839022088991	[218]	[99,81,56]	-6	hSpCas9	negative selection	2096929
64314354	64314377	11	-	26627737	HCT116	viability after 15 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.8568018301124399	[329]	[164,110,45]	-7	hSpCas9	negative selection	2096930
64315256	64315279	11	-	26627737	HCT116	viability after 15 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.5734510352673543	[375]	[145,190,98]	-5	hSpCas9	negative selection	2096931
64315257	64315280	11	-	26627737	HCT116	viability after 15 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.16128284926990744	[1053]	[639,631,365]	-2	hSpCas9	negative selection	2096932
64314045	64314068	11	+	26627737	HCT116	viability after 18 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2179242
64314270	64314293	11	+	26627737	HCT116	viability after 18 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	1.5985105217226065	[54]	[108,47,86]	9	hSpCas9	negative selection	2179243
64314273	64314296	11	+	26627737	HCT116	viability after 18 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.6739492095061015	[218]	[130,31,36]	-6	hSpCas9	negative selection	2179244
64314354	64314377	11	-	26627737	HCT116	viability after 18 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.8834866794412312	[329]	[148,55,54]	-7	hSpCas9	negative selection	2179245
64315256	64315279	11	-	26627737	HCT116	viability after 18 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.47600374970765524	[375]	[140,109,142]	-4	hSpCas9	negative selection	2179246
64315257	64315280	11	-	26627737	HCT116	viability after 18 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.10490243846569625	[1053]	[535,477,403]	-1	hSpCas9	negative selection	2179247
64307228	64307251	11	-	24336569	HL60	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	-0.18055235750979926	[805]	[1504]	-1	hSpCas9	negative selection	2263352
64307236	64307259	11	-	24336569	HL60	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	0.3529651947426643	[544]	[1472]	3	hSpCas9	negative selection	2263353
64307246	64307269	11	-	24336569	HL60	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	0.15436857764625966	[289]	[682]	1	hSpCas9	negative selection	2263354
64307256	64307279	11	-	24336569	HL60	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	0.8305567342115652	[130]	[492]	6	hSpCas9	negative selection	2263355
64307263	64307286	11	+	24336569	HL60	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	0.6306103179955991	[455]	[1493]	5	hSpCas9	negative selection	2263356
64307269	64307292	11	+	24336569	HL60	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	1.3675664397230993	[366]	[2003]	8	hSpCas9	negative selection	2263357
64307293	64307316	11	-	24336569	HL60	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-0.07626050602135659	[1106]	[2221]	0	hSpCas9	negative selection	2263358
64307300	64307323	11	-	24336569	HL60	viability	GGGAGGCAGCGAGTGGGAGCTGG	ESRRA	ENSG00000173153	-0.476776946397132	[677]	[1030]	-4	hSpCas9	negative selection	2263359
64307306	64307329	11	-	24336569	HL60	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-0.4071766703437728	[1001]	[1598]	-4	hSpCas9	negative selection	2263360
64307311	64307334	11	+	24336569	HL60	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	0.6080088890584666	[385]	[1244]	5	hSpCas9	negative selection	2263361
64307228	64307251	11	-	24336569	KBM7	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.3138697497428446	[519]	[1762]	3	hSpCas9	negative selection	2330529
64307236	64307259	11	-	24336569	KBM7	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	-0.1323769648498335	[429]	[1069]	-1	hSpCas9	negative selection	2330530
64307246	64307269	11	-	24336569	KBM7	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-0.27308146531674604	[244]	[552]	-2	hSpCas9	negative selection	2330531
64307256	64307279	11	-	24336569	KBM7	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-0.6895519868548465	[135]	[229]	-5	hSpCas9	negative selection	2330532
64307263	64307286	11	+	24336569	KBM7	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.9925934829427774	[649]	[890]	-6	hSpCas9	negative selection	2330533
64307269	64307292	11	+	24336569	KBM7	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	-0.32593607932164426	[448]	[976]	-3	hSpCas9	negative selection	2330534
64307293	64307316	11	-	24336569	KBM7	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-2.5331700652039584	[1058]	[498]	-8	hSpCas9	negative selection	2330535
64307300	64307323	11	-	24336569	KBM7	viability	GGGAGGCAGCGAGTGGGAGCTGG	ESRRA	ENSG00000173153	0.16857792577586778	[365]	[1121]	1	hSpCas9	negative selection	2330536
64307306	64307329	11	-	24336569	KBM7	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-0.8135883599003619	[539]	[837]	-6	hSpCas9	negative selection	2330537
64307311	64307334	11	+	24336569	KBM7	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	0.23205806023034078	[402]	[1290]	2	hSpCas9	negative selection	2330538
64306075	64306098	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGCTCTATGTCTGGGAAGGGG	ESRRA	ENSG00000173153	-2.0419581160891207	[583,79]	[29,2]	-9	dCas9-VP64	positive selection	2421738
64306028	64306051	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGGACTTCGGCAAATGCGGG	ESRRA	ENSG00000173153	0.9967469417569541	[13,49]	[21,4]	4	dCas9-VP64	positive selection	2421739
64306112	64306135	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGGCGCTCGAAGGGGCCTGG	ESRRA	ENSG00000173153	4.610143464330992	[21,25]	[242,8]	9	dCas9-VP64	positive selection	2421740
64306075	64306098	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGCTCTATGTCTGGGAAGGGG	ESRRA	ENSG00000173153	-0.022324692347913788	[122,88]	[36,30]	0	dCas9-VP64	positive selection	2516993
64306028	64306051	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGGACTTCGGCAAATGCGGG	ESRRA	ENSG00000173153	1.9742227034785949	[26,34]	[60,19]	8	dCas9-VP64	positive selection	2516994
64306112	64306135	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGGCGCTCGAAGGGGCCTGG	ESRRA	ENSG00000173153	-0.2999627851707056	[152,12]	[37,6]	-3	dCas9-VP64	positive selection	2516995
64314042	64314065	11	-	27260157	DLD1	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.626168578835299	[]	[]	-5	hSpCas9	negative selection	2574484
64307236	64307259	11	-	27260157	DLD1	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	-0.581093070705175	[]	[]	-5	hSpCas9	negative selection	2576429
64307263	64307286	11	+	27260157	DLD1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	0.33025736381968	[]	[]	4	hSpCas9	negative selection	2579258
64314273	64314296	11	+	27260157	DLD1	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.431988362257369	[]	[]	7	hSpCas9	negative selection	2581916
64307306	64307329	11	-	27260157	DLD1	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-2.55544555285291	[]	[]	-9	hSpCas9	negative selection	2604590
64307256	64307279	11	-	27260157	DLD1	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-1.86272727406976	[]	[]	-8	hSpCas9	negative selection	2604613
64307293	64307316	11	-	27260157	DLD1	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-1.4104091868112	[]	[]	-8	hSpCas9	negative selection	2607678
64315188	64315211	11	+	27260157	DLD1	viability	GCAACTAGTGCGGCGGCTGCAGG	ESRRA	ENSG00000173153	-0.0561102995199176	[]	[]	0	hSpCas9	negative selection	2608958
64307269	64307292	11	+	27260157	DLD1	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	-0.127220429596745	[]	[]	-1	hSpCas9	negative selection	2611690
64314042	64314065	11	+	27260157	DLD1	viability	CCTGCGGGTGGGCATGCTCAAGG	ESRRA	ENSG00000173153	-0.820145637159305	[]	[]	-6	hSpCas9	negative selection	2612650
64307292	64307315	11	-	27260157	DLD1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.79639117132793	[]	[]	-8	hSpCas9	negative selection	2616868
64307228	64307251	11	-	27260157	DLD1	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.624653082915795	[]	[]	8	hSpCas9	negative selection	2620421
64315250	64315273	11	-	27260157	DLD1	viability	ACCTGAATTGGCAAGGGCCAAGG	ESRRA	ENSG00000173153	-0.253511688656127	[]	[]	-2	hSpCas9	negative selection	2641043
64307311	64307334	11	+	27260157	DLD1	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	0.0345238418282675	[]	[]	0	hSpCas9	negative selection	2647372
64307246	64307269	11	-	27260157	DLD1	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-0.278512516779351	[]	[]	-2	hSpCas9	negative selection	2649605
64314042	64314065	11	-	27260157	HT1080	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-1.56844512536852	[]	[]	-9	hSpCas9	negative selection	2650614
64307236	64307259	11	-	27260157	HT1080	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	0.0595160955136802	[]	[]	0	hSpCas9	negative selection	2652559
64307263	64307286	11	+	27260157	HT1080	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.527043297752475	[]	[]	-7	hSpCas9	negative selection	2655388
64314273	64314296	11	+	27260157	HT1080	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	1.42242532268245	[]	[]	9	hSpCas9	negative selection	2658046
64307306	64307329	11	-	27260157	HT1080	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-1.94278899009184	[]	[]	-9	hSpCas9	negative selection	2680720
64307256	64307279	11	-	27260157	HT1080	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-0.238002558253809	[]	[]	0	hSpCas9	negative selection	2680743
64307293	64307316	11	-	27260157	HT1080	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-0.307963643984872	[]	[]	-7	hSpCas9	negative selection	2683808
64315188	64315211	11	+	27260157	HT1080	viability	GCAACTAGTGCGGCGGCTGCAGG	ESRRA	ENSG00000173153	-0.176705716844873	[]	[]	0	hSpCas9	negative selection	2685088
64307269	64307292	11	+	27260157	HT1080	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	-0.699338869296144	[]	[]	-8	hSpCas9	negative selection	2687820
64314042	64314065	11	+	27260157	HT1080	viability	CCTGCGGGTGGGCATGCTCAAGG	ESRRA	ENSG00000173153	-1.46530071941341	[]	[]	-9	hSpCas9	negative selection	2688780
64307292	64307315	11	-	27260157	HT1080	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.63730670137281	[]	[]	-9	hSpCas9	negative selection	2692998
64307228	64307251	11	-	27260157	HT1080	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.869934970220925	[]	[]	7	hSpCas9	negative selection	2696551
64315250	64315273	11	-	27260157	HT1080	viability	ACCTGAATTGGCAAGGGCCAAGG	ESRRA	ENSG00000173153	-0.148845159548004	[]	[]	0	hSpCas9	negative selection	2717173
64307311	64307334	11	+	27260157	HT1080	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	-0.782836243137512	[]	[]	-8	hSpCas9	negative selection	2723502
64307246	64307269	11	-	27260157	HT1080	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-0.180735663984752	[]	[]	0	hSpCas9	negative selection	2725735
64314042	64314065	11	-	27260157	MKN45	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-1.8387884153754	[]	[]	-9	hSpCas9	negative selection	2726744
64307236	64307259	11	-	27260157	MKN45	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	-0.102986387876276	[]	[]	0	hSpCas9	negative selection	2728689
64307263	64307286	11	+	27260157	MKN45	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-1.70651883748274	[]	[]	-9	hSpCas9	negative selection	2731518
64314273	64314296	11	+	27260157	MKN45	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	1.14579608739165	[]	[]	8	hSpCas9	negative selection	2734176
64307306	64307329	11	-	27260157	MKN45	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-2.92628897550802	[]	[]	-9	hSpCas9	negative selection	2756850
64307256	64307279	11	-	27260157	MKN45	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-2.07265916153395	[]	[]	-9	hSpCas9	negative selection	2756873
64307293	64307316	11	-	27260157	MKN45	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-1.45966953251059	[]	[]	-8	hSpCas9	negative selection	2759938
64315188	64315211	11	+	27260157	MKN45	viability	GCAACTAGTGCGGCGGCTGCAGG	ESRRA	ENSG00000173153	0.247361201216669	[]	[]	5	hSpCas9	negative selection	2761218
64307269	64307292	11	+	27260157	MKN45	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	0.0925012244959285	[]	[]	0	hSpCas9	negative selection	2763950
64314042	64314065	11	+	27260157	MKN45	viability	CCTGCGGGTGGGCATGCTCAAGG	ESRRA	ENSG00000173153	-2.09666795890393	[]	[]	-9	hSpCas9	negative selection	2764910
64307292	64307315	11	-	27260157	MKN45	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-0.941793133108342	[]	[]	-7	hSpCas9	negative selection	2769128
64307228	64307251	11	-	27260157	MKN45	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.628214113246267	[]	[]	7	hSpCas9	negative selection	2772681
64315250	64315273	11	-	27260157	MKN45	viability	ACCTGAATTGGCAAGGGCCAAGG	ESRRA	ENSG00000173153	-0.855519440624441	[]	[]	-7	hSpCas9	negative selection	2793303
64307311	64307334	11	+	27260157	MKN45	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	-1.20974388204245	[]	[]	-8	hSpCas9	negative selection	2799632
64307246	64307269	11	-	27260157	MKN45	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-1.55373658355714	[]	[]	-9	hSpCas9	negative selection	2801865
64314042	64314065	11	-	27260157	RKO	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-1.23008038554404	[]	[]	-8	hSpCas9	negative selection	2802874
64307236	64307259	11	-	27260157	RKO	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	-0.188640332873682	[]	[]	-1	hSpCas9	negative selection	2804819
64307263	64307286	11	+	27260157	RKO	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.320054244468815	[]	[]	-6	hSpCas9	negative selection	2807648
64314273	64314296	11	+	27260157	RKO	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	1.65059914126421	[]	[]	9	hSpCas9	negative selection	2810306
64307306	64307329	11	-	27260157	RKO	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-3.59627139437393	[]	[]	-9	hSpCas9	negative selection	2832980
64307256	64307279	11	-	27260157	RKO	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-0.801399326267401	[]	[]	-7	hSpCas9	negative selection	2833003
64307293	64307316	11	-	27260157	RKO	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-1.51809381868398	[]	[]	-8	hSpCas9	negative selection	2836068
64315188	64315211	11	+	27260157	RKO	viability	GCAACTAGTGCGGCGGCTGCAGG	ESRRA	ENSG00000173153	0.255753154830019	[]	[]	1	hSpCas9	negative selection	2837348
64307269	64307292	11	+	27260157	RKO	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	-0.76340968543363	[]	[]	-7	hSpCas9	negative selection	2840080
64314042	64314065	11	+	27260157	RKO	viability	CCTGCGGGTGGGCATGCTCAAGG	ESRRA	ENSG00000173153	-1.61874094993234	[]	[]	-9	hSpCas9	negative selection	2841040
64307292	64307315	11	-	27260157	RKO	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.05396668860541	[]	[]	-9	hSpCas9	negative selection	2845258
64307228	64307251	11	-	27260157	RKO	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.576632260514028	[]	[]	3	hSpCas9	negative selection	2848811
64315250	64315273	11	-	27260157	RKO	viability	ACCTGAATTGGCAAGGGCCAAGG	ESRRA	ENSG00000173153	0.486055785241633	[]	[]	2	hSpCas9	negative selection	2869433
64307311	64307334	11	+	27260157	RKO	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	-0.753455854518436	[]	[]	-7	hSpCas9	negative selection	2875762
64307246	64307269	11	-	27260157	RKO	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-0.830474621771624	[]	[]	-7	hSpCas9	negative selection	2877995
64314042	64314065	11	-	27260157	SF268	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-1.98310156311676	[]	[]	-8	hSpCas9	negative selection	2879004
64307236	64307259	11	-	27260157	SF268	viability	AGGAACCCTTTGGACTGTCAGGG	ESRRA	ENSG00000173153	-0.170579147484227	[]	[]	-1	hSpCas9	negative selection	2880949
64307263	64307286	11	+	27260157	SF268	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.124837346369936	[]	[]	-1	hSpCas9	negative selection	2883778
64314273	64314296	11	+	27260157	SF268	viability	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.638345925632877	[]	[]	8	hSpCas9	negative selection	2886436
64307306	64307329	11	-	27260157	SF268	viability	TGGCCTGGGAGGCAGCGAGTGGG	ESRRA	ENSG00000173153	-2.86091909781879	[]	[]	-9	hSpCas9	negative selection	2909110
64307256	64307279	11	-	27260157	SF268	viability	AGGCTCGGTCTCTGTCTCCGAGG	ESRRA	ENSG00000173153	-0.546614496591205	[]	[]	-4	hSpCas9	negative selection	2909133
64307293	64307316	11	-	27260157	SF268	viability	AGCGAGTGGGAGCTGGACCAGGG	ESRRA	ENSG00000173153	-1.28439449029911	[]	[]	-7	hSpCas9	negative selection	2912198
64315188	64315211	11	+	27260157	SF268	viability	GCAACTAGTGCGGCGGCTGCAGG	ESRRA	ENSG00000173153	0.866905576606492	[]	[]	9	hSpCas9	negative selection	2913478
64307269	64307292	11	+	27260157	SF268	viability	GACCGAGCCTCCTGTGGCCCTGG	ESRRA	ENSG00000173153	0.617000094097399	[]	[]	8	hSpCas9	negative selection	2916210
64314042	64314065	11	+	27260157	SF268	viability	CCTGCGGGTGGGCATGCTCAAGG	ESRRA	ENSG00000173153	-2.23287396959978	[]	[]	-9	hSpCas9	negative selection	2917170
64307292	64307315	11	-	27260157	SF268	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.04635816104591	[]	[]	-8	hSpCas9	negative selection	2921388
64307228	64307251	11	-	27260157	SF268	viability	TTTGGACTGTCAGGGCTGGCCGG	ESRRA	ENSG00000173153	0.458632852493031	[]	[]	7	hSpCas9	negative selection	2924941
64315250	64315273	11	-	27260157	SF268	viability	ACCTGAATTGGCAAGGGCCAAGG	ESRRA	ENSG00000173153	0.333017368088951	[]	[]	4	hSpCas9	negative selection	2945563
64307311	64307334	11	+	27260157	SF268	viability	TCGCTGCCTCCCAGGCCACAAGG	ESRRA	ENSG00000173153	-0.385163135545198	[]	[]	-3	hSpCas9	negative selection	2951892
64307246	64307269	11	-	27260157	SF268	viability	TCTGTCTCCGAGGAACCCTTTGG	ESRRA	ENSG00000173153	-0.932738443158641	[]	[]	-6	hSpCas9	negative selection	2954125
64313982	64314005	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	0.2406631438781775	[2,2]	[0,4]	5	hSpCas9	positive selection	2986449
64314744	64314767	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	0.38952115546242144	[3,3]	[4,3]	7	hSpCas9	positive selection	2986450
64307232	64307255	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	-0.8660981841632794	[2,3]	[1,0]	-8	hSpCas9	positive selection	2986451
64307355	64307378	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	-0.1254299882799026	[1,2]	[1,0]	-2	hSpCas9	positive selection	2986452
64313982	64314005	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	-0.5049782428245545	[2,2]	[2,0]	-7	hSpCas9	positive selection	3054307
64314744	64314767	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	0.2369730961803716	[3,3]	[3,2]	4	hSpCas9	positive selection	3054308
64307232	64307255	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	0.2684054708357095	[2,2]	[2,2]	5	hSpCas9	positive selection	3054309
64307355	64307378	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	-0.12085857996662674	[1,1]	[1,0]	-2	hSpCas9	positive selection	3054310
64314018	64314041		-	24336571	A375	resistance to PLX after 7 days	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.0635354094803285	[13,13]	[13,12]	-2	hSpCas9	positive selection	3112589
64314228	64314251		+	24336571	A375	resistance to PLX after 7 days	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.1757034082164406	[7,7]	[6,6]	-5	hSpCas9	positive selection	3112590
64314018	64314041		-	24336571	A375	resistance to PLX after 14 days	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	1.9908153626888105	[9,15]	[22,25]	9	hSpCas9	positive selection	3170382
64314228	64314251		+	24336571	A375	resistance to PLX after 14 days	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.20519527746708754	[8,4]	[2,2]	-2	hSpCas9	positive selection	3170383
64314018	64314041		-	24336571	A375	viability after 7 days	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.6695186399012689	[8]	[13,13]	8	hSpCas9	negative selection	3228175
64314228	64314251		+	24336571	A375	viability after 7 days	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.13601272884286097	[7]	[7,7]	2	hSpCas9	negative selection	3228176
64314018	64314041		-	24336571	A375	viability after 14 days	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.5888493828636729	[8]	[9,15]	7	hSpCas9	negative selection	3285968
64314228	64314251		+	24336571	A375	viability after 14 days	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.010588499706111199	[7]	[8,4]	0	hSpCas9	negative selection	3285969
64314228	64314251	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.36989651190370554	[101,134]	[0,0]	2	hSpCas9	positive selection	3348414
64315257	64315280	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.3929377337840722	[118,113]	[0,0]	2	hSpCas9	positive selection	3348415
64314797	64314820	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	1.036702882962443	[85,62]	[0,0]	5	hSpCas9	positive selection	3348416
64314018	64314041	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3367620
64315233	64315256	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.14880175466766601	[137,137]	[0,0]	0	hSpCas9	positive selection	3367621
64314042	64314065	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-1.737027225413023	[509,509]	[0,0]	-9	hSpCas9	positive selection	3367622
64313981	64314004	11	+	26780180	HT29	viability (Avana library 4 designs)	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	4.62194956752171	[]	[]	9	hSpCas9	negative selection	3423280
64314744	64314767	11	-	26780180	HT29	viability (Avana library 4 designs)	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	2.67843457397125	[]	[]	8	hSpCas9	negative selection	3423281
64307231	64307254	11	+	26780180	HT29	viability (Avana library 4 designs)	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	1.79931499627134	[]	[]	7	hSpCas9	negative selection	3423282
64307354	64307377	11	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	3.23565814431105	[]	[]	8	hSpCas9	negative selection	3423283
64307231	64307254	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	2.58916043680297	[]	[]	4	hSpCas9	negative selection	3504359
64313981	64314004	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	4.32239511489351	[]	[]	7	hSpCas9	negative selection	3504360
64314744	64314767	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	3.02029874261106	[]	[]	4	hSpCas9	negative selection	3504361
64307354	64307377	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	-4.9799514087014	[]	[]	-5	hSpCas9	negative selection	3504362
64314757	64314780	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGTGTCTCATCTGCTGGTGG	ESRRA	ENSG00000173153	0.234381143778566	[]	[]	0	hSpCas9	negative selection	3504363
64313975	64313998	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGATCTCACACTCGTTGGAGG	ESRRA	ENSG00000173153	-3.52208683863862	[]	[]	-4	hSpCas9	negative selection	3504364
64307231	64307254	11	+	26780180	A375	viability (Avana lentiGuide)	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	-3.66780221529696	[]	[]	-6	hSpCas9	negative selection	3613018
64313981	64314004	11	+	26780180	A375	viability (Avana lentiGuide)	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	-5.08428661381101	[]	[]	-8	hSpCas9	negative selection	3613019
64314744	64314767	11	-	26780180	A375	viability (Avana lentiGuide)	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	8.69109859773673	[]	[]	6	hSpCas9	negative selection	3613020
64307354	64307377	11	+	26780180	A375	viability (Avana lentiGuide)	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	17.6715238998131	[]	[]	8	hSpCas9	negative selection	3613021
64314757	64314780	11	+	26780180	A375	viability (Avana lentiGuide)	ACTGGTGTCTCATCTGCTGGTGG	ESRRA	ENSG00000173153	13.7927765482105	[]	[]	7	hSpCas9	negative selection	3613022
64313975	64313998	11	-	26780180	A375	viability (Avana lentiGuide)	GGTGATCTCACACTCGTTGGAGG	ESRRA	ENSG00000173153	5.07232359611545	[]	[]	4	hSpCas9	negative selection	3613023
64307231	64307254	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	0.2077835799258935	[3]	[5,3]	6	hSpCas9	positive selection	3721677
64313981	64314004	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	-0.010007524247406363	[4]	[4,4]	0	hSpCas9	positive selection	3721678
64314744	64314767	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	-0.010814696991437112	[5]	[5,5]	0	hSpCas9	positive selection	3721679
64307354	64307377	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	-0.4691858380591982	[4]	[2,2]	-6	hSpCas9	positive selection	3721680
64314757	64314780	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGTGTCTCATCTGCTGGTGG	ESRRA	ENSG00000173153	0.042174106683055	[4]	[5,4]	1	hSpCas9	positive selection	3721681
64313975	64313998	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGATCTCACACTCGTTGGAGG	ESRRA	ENSG00000173153	-0.03569064556982102	[4]	[5,4]	0	hSpCas9	positive selection	3721682
64307231	64307254	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGCCCTGACAGTCCAAAGGG	ESRRA	ENSG00000173153	0.10173024040642314	[4]	[3,3]	2	hSpCas9	positive selection	3830284
64313981	64314004	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGAGTGTGAGATCACCAAGCGG	ESRRA	ENSG00000173153	-0.2612854447558177	[4]	[3,2]	-4	hSpCas9	positive selection	3830285
64314744	64314767	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACACCAGTGCATTCACTGGGG	ESRRA	ENSG00000173153	-0.7667734286619212	[5]	[1,3]	-7	hSpCas9	positive selection	3830286
64307354	64307377	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCCTGGCGAGCAGGGCGG	ESRRA	ENSG00000173153	-1.1792805177770591	[4]	[0,1]	-9	hSpCas9	positive selection	3830287
64314757	64314780	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGTGTCTCATCTGCTGGTGG	ESRRA	ENSG00000173153	0.01555231785150012	[5]	[1,7]	0	hSpCas9	positive selection	3830288
64313975	64313998	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGATCTCACACTCGTTGGAGG	ESRRA	ENSG00000173153	-0.11021688000663744	[5]	[5,2]	-1	hSpCas9	positive selection	3830289
64314018	64314041	11	-	26780180	A375	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.917308408815504	[]	[]	4	hSpCas9	negative selection	3937632
64314228	64314251	11	+	26780180	A375	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.68807143981061	[]	[]	2	hSpCas9	negative selection	3937633
64315257	64315280	11	-	26780180	A375	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.888185885395182	[]	[]	4	hSpCas9	negative selection	3937634
64314042	64314065	11	-	26780180	A375	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	1.85865980871824	[]	[]	9	hSpCas9	negative selection	3937635
64315233	64315256	11	+	26780180	A375	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	1.50988784659843	[]	[]	8	hSpCas9	negative selection	3937636
64314797	64314820	11	+	26780180	A375	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	1.57091296110203	[]	[]	8	hSpCas9	negative selection	3937637
64314018	64314041	11	-	26780180	HT29	viability (GeCKOv2 library)	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	1.40521184863725	[]	[]	7	hSpCas9	negative selection	4045598
64314228	64314251	11	+	26780180	HT29	viability (GeCKOv2 library)	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	1.16775036296517	[]	[]	5	hSpCas9	negative selection	4045599
64315257	64315280	11	-	26780180	HT29	viability (GeCKOv2 library)	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.895024069494941	[]	[]	4	hSpCas9	negative selection	4045600
64314042	64314065	11	-	26780180	HT29	viability (GeCKOv2 library)	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	1.98200837266978	[]	[]	9	hSpCas9	negative selection	4045601
64315233	64315256	11	+	26780180	HT29	viability (GeCKOv2 library)	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	1.53004489583118	[]	[]	7	hSpCas9	negative selection	4045602
64314797	64314820	11	+	26780180	HT29	viability (GeCKOv2 library)	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	1.40791569190005	[]	[]	7	hSpCas9	negative selection	4045603
64314018	64314041	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.41928276476295184	[3]	[2,4]	8	hSpCas9	positive selection	4135324
64314228	64314251	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.06544410926176297	[2]	[2,1]	1	hSpCas9	positive selection	4135325
64314018	64314041	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.15770096860259325	[2]	[0,2,0,0]	1	hSpCas9	positive selection	4199346
64314228	64314251	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.22831961796783895	[2]	[0,2,2,0]	1	hSpCas9	positive selection	4199347
64314228	64314251	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.04412727792703356	[2]	[3,1]	0	hSpCas9	positive selection	4269282
64315257	64315280	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.48813611619645536	[2]	[3,3]	8	hSpCas9	positive selection	4269283
64314797	64314820	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.14485207376104015	[2]	[2,0]	-3	hSpCas9	positive selection	4269284
64314018	64314041	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.3155750918515512	[2]	[2,0]	-6	hSpCas9	positive selection	4333547
64315233	64315256	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.2815677958077658	[2]	[2,2]	5	hSpCas9	positive selection	4333548
64314042	64314065	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.03485667854107993	[4]	[3,3]	0	hSpCas9	positive selection	4333549
64314229	64314251	11	+	27760321	OCIAML3	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.06950143994626967	[763,599]	[486,645]	0	hSpCas9	negative selection	4398450
64314264	64314286	11	+	27760321	OCIAML3	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	0.11415613237303268	[169,129]	[125,125]	1	hSpCas9	negative selection	4398451
64314836	64314858	11	-	27760321	OCIAML3	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.2565387577712037	[819,733]	[481,541]	-3	hSpCas9	negative selection	4398452
64314859	64314881	11	-	27760321	OCIAML3	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.5071492259615554	[373,337]	[321,490]	6	hSpCas9	negative selection	4398453
64314897	64314919	11	+	27760321	OCIAML3	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.09972446162633652	[289,249]	[219,232]	1	hSpCas9	negative selection	4398454
64314229	64314251	11	+	27760321	OCIAML2	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.37288631135113937	[763,599]	[644,794]	5	hSpCas9	negative selection	4481913
64314264	64314286	11	+	27760321	OCIAML2	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-0.9108406301194079	[169,129]	[98,17]	-7	hSpCas9	negative selection	4481914
64314836	64314858	11	-	27760321	OCIAML2	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.702852136513375	[819,733]	[307,487]	-6	hSpCas9	negative selection	4481915
64314859	64314881	11	-	27760321	OCIAML2	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	-0.09176829756706822	[373,337]	[247,298]	-1	hSpCas9	negative selection	4481916
64314897	64314919	11	+	27760321	OCIAML2	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.47613461779559313	[289,249]	[264,352]	6	hSpCas9	negative selection	4481917
64314229	64314251	11	+	27760321	MV411	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.23381217121222975	[763,599]	[135,746]	-2	hSpCas9	negative selection	4565376
64314264	64314286	11	+	27760321	MV411	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	0.9929245030419729	[169,129]	[65,389]	7	hSpCas9	negative selection	4565377
64314836	64314858	11	-	27760321	MV411	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.8594686082251294	[819,733]	[95,561]	-5	hSpCas9	negative selection	4565378
64314859	64314881	11	-	27760321	MV411	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.5521488354409027	[373,337]	[300,408]	4	hSpCas9	negative selection	4565379
64314897	64314919	11	+	27760321	MV411	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	1.6002142764574265	[289,249]	[405,737]	9	hSpCas9	negative selection	4565380
64314229	64314251	11	+	27760321	HL60	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.7603589191262614	[763,599]	[969,902]	8	hSpCas9	negative selection	4648839
64314264	64314286	11	+	27760321	HL60	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	1.3845357847027007	[169,129]	[249,388]	9	hSpCas9	negative selection	4648840
64314836	64314858	11	-	27760321	HL60	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	0.38620901439035094	[819,733]	[728,933]	5	hSpCas9	negative selection	4648841
64314859	64314881	11	-	27760321	HL60	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	1.3533166396552758	[373,337]	[621,869]	9	hSpCas9	negative selection	4648842
64314897	64314919	11	+	27760321	HL60	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	1.4536449811660992	[289,249]	[582,622]	9	hSpCas9	negative selection	4648843
64314229	64314251	11	+	27760321	HT1080	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.1306863238560046	[599,467]	[168,221]	0	hSpCas9	negative selection	4732302
64314264	64314286	11	+	27760321	HT1080	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	0.7039334967949757	[129,101]	[49,102]	4	hSpCas9	negative selection	4732303
64314836	64314858	11	-	27760321	HT1080	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-1.3269051807769805	[733,572]	[77,131]	-5	hSpCas9	negative selection	4732304
64314859	64314881	11	-	27760321	HT1080	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.8707965947569567	[337,263]	[140,304]	5	hSpCas9	negative selection	4732305
64314897	64314919	11	+	27760321	HT1080	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	2.6417623315644727	[249,194]	[271,860]	9	hSpCas9	negative selection	4732306
64314229	64314251	11	+	27760321	HT29	viability after 7 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.008573215413605673	[599,467]	[560,749,716]	0	hSpCas9	negative selection	4815765
64314264	64314286	11	+	27760321	HT29	viability after 7 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-0.06623451788907753	[129,101]	[172,95,161]	-1	hSpCas9	negative selection	4815766
64314836	64314858	11	-	27760321	HT29	viability after 7 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.5186525303159966	[733,572]	[617,617,528]	-6	hSpCas9	negative selection	4815767
64314859	64314881	11	-	27760321	HT29	viability after 7 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.22758901408146198	[337,263]	[422,557,375]	3	hSpCas9	negative selection	4815768
64314897	64314919	11	+	27760321	HT29	viability after 7 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.7468061994108951	[249,194]	[603,338,512]	9	hSpCas9	negative selection	4815769
64314229	64314251	11	+	27760321	HT29	viability after 25 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.0054831682616443	[599,467]	[447,698,694]	0	hSpCas9	negative selection	4899228
64314264	64314286	11	+	27760321	HT29	viability after 25 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-1.7044068198532538	[129,101]	[62,47,5]	-7	hSpCas9	negative selection	4899229
64314836	64314858	11	-	27760321	HT29	viability after 25 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.7971116803403898	[733,572]	[629,303,331]	-6	hSpCas9	negative selection	4899230
64314859	64314881	11	-	27760321	HT29	viability after 25 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	-0.48211596717204336	[337,263]	[132,362,249]	-4	hSpCas9	negative selection	4899231
64314897	64314919	11	+	27760321	HT29	viability after 25 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	-0.004940456937310267	[249,194]	[168,205,405]	0	hSpCas9	negative selection	4899232
64314229	64314251	11	+	27760321	HT29	viability after 22 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.12706275854835614	[599,467]	[467,706,522]	-1	hSpCas9	negative selection	4982691
64314264	64314286	11	+	27760321	HT29	viability after 22 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-2.372844088023273	[129,101]	[44,24,6]	-8	hSpCas9	negative selection	4982692
64314836	64314858	11	-	27760321	HT29	viability after 22 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.7634854166581678	[733,572]	[649,187,491]	-6	hSpCas9	negative selection	4982693
64314859	64314881	11	-	27760321	HT29	viability after 22 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	-0.4094011687763102	[337,263]	[249,310,224]	-4	hSpCas9	negative selection	4982694
64314897	64314919	11	+	27760321	HT29	viability after 22 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	-0.15049429632400657	[249,194]	[188,206,300]	-1	hSpCas9	negative selection	4982695
64314229	64314251	11	+	27760321	HT29	viability after 19 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.790471653394712	[599,467]	[312,259,476]	-6	hSpCas9	negative selection	5066154
64314264	64314286	11	+	27760321	HT29	viability after 19 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-2.245283473891864	[129,101]	[77,4,6]	-8	hSpCas9	negative selection	5066155
64314836	64314858	11	-	27760321	HT29	viability after 19 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.8516452469454233	[733,572]	[393,615,236]	-6	hSpCas9	negative selection	5066156
64314859	64314881	11	-	27760321	HT29	viability after 19 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.26806185969017915	[337,263]	[66,483,646]	2	hSpCas9	negative selection	5066157
64314897	64314919	11	+	27760321	HT29	viability after 19 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.2618861129890092	[249,194]	[352,70,488]	2	hSpCas9	negative selection	5066158
64314229	64314251	11	+	27760321	HT29	viability after 16 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.4370685215983148	[599,467]	[703,309,337]	-4	hSpCas9	negative selection	5149617
64314264	64314286	11	+	27760321	HT29	viability after 16 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-1.3436046729943985	[129,101]	[22,119,5]	-7	hSpCas9	negative selection	5149618
64314836	64314858	11	-	27760321	HT29	viability after 16 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.7252673966032956	[733,572]	[515,429,387]	-6	hSpCas9	negative selection	5149619
64314859	64314881	11	-	27760321	HT29	viability after 16 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	-0.36390910413397165	[337,263]	[209,305,262]	-4	hSpCas9	negative selection	5149620
64314897	64314919	11	+	27760321	HT29	viability after 16 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.5792111843616188	[249,194]	[432,272,417]	6	hSpCas9	negative selection	5149621
64314229	64314251	11	+	27760321	HT29	viability after 13 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.3468173446947147	[599,467]	[399,498,557]	-4	hSpCas9	negative selection	5233080
64314264	64314286	11	+	27760321	HT29	viability after 13 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	0.0323202555048725	[129,101]	[95,92,218]	0	hSpCas9	negative selection	5233081
64314836	64314858	11	-	27760321	HT29	viability after 13 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.4080886796956385	[733,572]	[633,545,535]	-5	hSpCas9	negative selection	5233082
64314859	64314881	11	-	27760321	HT29	viability after 13 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.10885426295426953	[337,263]	[380,343,402]	1	hSpCas9	negative selection	5233083
64314897	64314919	11	+	27760321	HT29	viability after 13 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.07447629533500555	[249,194]	[263,324,228]	0	hSpCas9	negative selection	5233084
64314229	64314251	11	+	27760321	HT29	viability after 10 days	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.08879033633618993	[599,467]	[656,620,602]	-1	hSpCas9	negative selection	5316543
64314264	64314286	11	+	27760321	HT29	viability after 10 days	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	-0.6727325467607157	[129,101]	[63,69,136]	-7	hSpCas9	negative selection	5316544
64314836	64314858	11	-	27760321	HT29	viability after 10 days	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.3995903269273397	[733,572]	[754,626,476]	-5	hSpCas9	negative selection	5316545
64314859	64314881	11	-	27760321	HT29	viability after 10 days	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	0.1709633663017929	[337,263]	[84,668,519]	2	hSpCas9	negative selection	5316546
64314897	64314919	11	+	27760321	HT29	viability after 10 days	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	0.21958491591061807	[249,194]	[277,276,411]	3	hSpCas9	negative selection	5316547
64314229	64314251	11	+	27760321	MOLM13	viability	ACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.007658292584393656	[763,599]	[514,272]	0	hSpCas9	negative selection	5400006
64314264	64314286	11	+	27760321	MOLM13	viability	TGGGCGGCAGAAGTACAAGCGG	ESRRA	ENSG00000173153	0.18886419066094828	[169,129]	[206,0]	1	hSpCas9	negative selection	5400007
64314836	64314858	11	-	27760321	MOLM13	viability	CACAGAGGGTAGCCACGGCTGG	ESRRA	ENSG00000173153	-0.04168641159701025	[819,733]	[433,417]	0	hSpCas9	negative selection	5400008
64314859	64314881	11	-	27760321	MOLM13	viability	CACAATCTCTCGGTCAAAGAGG	ESRRA	ENSG00000173153	1.848988142808825	[373,337]	[716,727]	9	hSpCas9	negative selection	5400009
64314897	64314919	11	+	27760321	MOLM13	viability	CCAAGAGCATCCCAGGTAAAGG	ESRRA	ENSG00000173153	4.908213787068245	[289,249]	[8671,1061]	9	hSpCas9	negative selection	5400010
64314228	64314251	11	+	27260156	BXPC3	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5843016659010205	[388]	[497,825,499,607]	9	hSpCas9	negative selection	5541742
64315257	64315280	11	-	27260156	BXPC3	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.3095708442633224	[374]	[474,528,391,548]	6	hSpCas9	negative selection	5541743
64314797	64314820	11	+	27260156	BXPC3	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.14758672656796828	[367]	[387,328,351,309]	-3	hSpCas9	negative selection	5541744
64314018	64314041	11	-	27260156	BXPC3	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.4720792241599567	[368]	[561,511,567,487]	8	hSpCas9	negative selection	5606007
64315233	64315256	11	+	27260156	BXPC3	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.017941176924694713	[341]	[342,266,430,420]	0	hSpCas9	negative selection	5606008
64314042	64314065	11	-	27260156	BXPC3	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.11298327884242143	[1268]	[1087,1236,1197,1412]	-3	hSpCas9	negative selection	5606009
64314228	64314251	11	+	27260156	A673	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.361505973244359	[388]	[716,583,510,601]	8	hSpCas9	negative selection	5662993
64315257	64315280	11	-	27260156	A673	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.4379351151000827	[374]	[723,548,581,597]	8	hSpCas9	negative selection	5662994
64314797	64314820	11	+	27260156	A673	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.08401737772654466	[367]	[389,501,476,494]	2	hSpCas9	negative selection	5662995
64314018	64314041	11	-	27260156	A673	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.14286850227668302	[368]	[516,491,448,501]	3	hSpCas9	negative selection	5727258
64315233	64315256	11	+	27260156	A673	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.0285252734898227	[341]	[482,442,302,388]	0	hSpCas9	negative selection	5727259
64314042	64314065	11	-	27260156	A673	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	0.04479101438898159	[1268]	[1732,1572,1452,1542]	1	hSpCas9	negative selection	5727260
64314228	64314251	11	+	27260156	A375	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.2984285063586391	[388]	[691,675,506,394]	4	hSpCas9	negative selection	5784244
64315257	64315280	11	-	27260156	A375	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.38060296384225406	[374]	[511,462,437,819]	5	hSpCas9	negative selection	5784245
64314797	64314820	11	+	27260156	A375	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.7162564245490062	[367]	[421,223,203,198]	-7	hSpCas9	negative selection	5784246
64314018	64314041	11	-	27260156	A375	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.01412880598645544	[368]	[340,614,348,455]	0	hSpCas9	negative selection	5848509
64315233	64315256	11	+	27260156	A375	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.10515350824281416	[341]	[377,504,450,396]	1	hSpCas9	negative selection	5848510
64314042	64314065	11	-	27260156	A375	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.1960926103868248	[1268]	[1241,1465,1415,1093]	-3	hSpCas9	negative selection	5848511
64314228	64314251	11	+	27260156	COLO741	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.6641119000509065	[388]	[922,853,608]	9	hSpCas9	negative selection	5905495
64315257	64315280	11	-	27260156	COLO741	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.45757705816355637	[374]	[795,726,474]	8	hSpCas9	negative selection	5905496
64314797	64314820	11	+	27260156	COLO741	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.03593996732247151	[367]	[533,442,407]	0	hSpCas9	negative selection	5905497
64314018	64314041	11	-	27260156	COLO741	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.0511592716534936	[368]	[508,479,384]	-1	hSpCas9	negative selection	5969760
64315233	64315256	11	+	27260156	COLO741	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.010593193414548063	[341]	[415,466,434]	0	hSpCas9	negative selection	5969761
64314042	64314065	11	-	27260156	COLO741	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.36086484094209514	[1268]	[1383,1315,1106]	-6	hSpCas9	negative selection	5969762
64314228	64314251	11	+	27260156	CAL120	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.634098203246237	[388]	[1145,535,632]	8	hSpCas9	negative selection	6026746
64315257	64315280	11	-	27260156	CAL120	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.3867872406689522	[374]	[847,523,495]	6	hSpCas9	negative selection	6026747
64314797	64314820	11	+	27260156	CAL120	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.7888593384801319	[367]	[187,248,344]	-8	hSpCas9	negative selection	6026748
64314018	64314041	11	-	27260156	CAL120	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.18084462492886094	[368]	[784,290,524]	2	hSpCas9	negative selection	6091011
64315233	64315256	11	+	27260156	CAL120	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.11971452205988764	[341]	[285,368,501]	-2	hSpCas9	negative selection	6091012
64314042	64314065	11	-	27260156	CAL120	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.2439543784890854	[1268]	[846,1654,1422]	-4	hSpCas9	negative selection	6091013
64314228	64314251	11	+	27260156	CADOES1	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.8824622596010463	[388]	[540,711,729,685]	9	hSpCas9	negative selection	6147997
64315257	64315280	11	-	27260156	CADOES1	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.7979275614891377	[374]	[809,592,491,526]	9	hSpCas9	negative selection	6147998
64314797	64314820	11	+	27260156	CADOES1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.3717752639479121	[367]	[182,345,300,226]	-6	hSpCas9	negative selection	6147999
64314018	64314041	11	-	27260156	CADOES1	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.36938158915396985	[368]	[600,429,398,338]	6	hSpCas9	negative selection	6212262
64315233	64315256	11	+	27260156	CADOES1	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.2657156735801256	[341]	[393,269,516,346]	4	hSpCas9	negative selection	6212263
64314042	64314065	11	-	27260156	CADOES1	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.17304851666601517	[1268]	[949,1113,967,1159]	-3	hSpCas9	negative selection	6212264
64314228	64314251	11	+	27260156	EWS502	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5435978479544472	[388]	[487,628,675,621]	8	hSpCas9	negative selection	6269248
64315257	64315280	11	-	27260156	EWS502	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.4112835301245986	[374]	[563,487,448,611]	7	hSpCas9	negative selection	6269249
64314797	64314820	11	+	27260156	EWS502	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.30980548359931187	[367]	[261,330,352,316]	-5	hSpCas9	negative selection	6269250
64314018	64314041	11	-	27260156	EWS502	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.2701123559789264	[368]	[448,523,543,359]	5	hSpCas9	negative selection	6333513
64315233	64315256	11	+	27260156	EWS502	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.01321076561883433	[341]	[487,306,337,281]	0	hSpCas9	negative selection	6333514
64314042	64314065	11	-	27260156	EWS502	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.24654433502232065	[1268]	[946,1206,1257,1136]	-4	hSpCas9	negative selection	6333515
64314228	64314251	11	+	27260156	EW8	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5827977943317253	[388]	[532,339,442,581]	8	hSpCas9	negative selection	6390499
64315257	64315280	11	-	27260156	EW8	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5927494043638561	[374]	[493,430,456,453]	9	hSpCas9	negative selection	6390500
64314797	64314820	11	+	27260156	EW8	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.10619904706293182	[367]	[477,146,269,412]	2	hSpCas9	negative selection	6390501
64314018	64314041	11	-	27260156	EW8	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.3105151194729717	[368]	[409,295,323,463]	5	hSpCas9	negative selection	6454764
64315233	64315256	11	+	27260156	EW8	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.031216450548717967	[341]	[304,295,193,305]	0	hSpCas9	negative selection	6454765
64314042	64314065	11	-	27260156	EW8	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.3415647974302234	[1268]	[840,898,769,744]	-6	hSpCas9	negative selection	6454766
64314228	64314251	11	+	27260156	CORL105	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.1972926013326501	[388]	[458,550,562,518]	3	hSpCas9	negative selection	6511750
64315257	64315280	11	-	27260156	CORL105	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.17878579416568507	[374]	[380,318,468,395]	-3	hSpCas9	negative selection	6511751
64314797	64314820	11	+	27260156	CORL105	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.4230726583906042	[367]	[244,369,330,336]	-6	hSpCas9	negative selection	6511752
64314018	64314041	11	-	27260156	CORL105	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.2938813805588675	[368]	[681,499,457,472]	5	hSpCas9	negative selection	6576015
64315233	64315256	11	+	27260156	CORL105	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.5264035369323691	[341]	[327,251,270,261]	-7	hSpCas9	negative selection	6576016
64314042	64314065	11	-	27260156	CORL105	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.28002017217173325	[1268]	[1248,1158,1419,1098]	-5	hSpCas9	negative selection	6576017
64314228	64314251	11	+	27260156	HS294T	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.8460651738505985	[388]	[499,171,196,176]	9	hSpCas9	negative selection	6633001
64315257	64315280	11	-	27260156	HS294T	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.46436790588989907	[374]	[181,154,194,284]	6	hSpCas9	negative selection	6633002
64314797	64314820	11	+	27260156	HS294T	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.6857306106983838	[367]	[331,117,221,237]	8	hSpCas9	negative selection	6633003
64314018	64314041	11	-	27260156	HS294T	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.32333521662339787	[368]	[137,308,146,106]	4	hSpCas9	negative selection	6697266
64315233	64315256	11	+	27260156	HS294T	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.18739747004910356	[341]	[165,252,75,91]	2	hSpCas9	negative selection	6697267
64314042	64314065	11	-	27260156	HS294T	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	0.15712580593443093	[1268]	[372,544,521,806]	2	hSpCas9	negative selection	6697268
64314228	64314251	11	+	27260156	HCC44	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.30871823608590676	[388]	[694,576,423,469]	5	hSpCas9	negative selection	6754252
64315257	64315280	11	-	27260156	HCC44	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.22986789402699623	[374]	[661,479,480,380]	3	hSpCas9	negative selection	6754253
64314797	64314820	11	+	27260156	HCC44	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.23367186873272222	[367]	[297,308,413,401]	-4	hSpCas9	negative selection	6754254
64314018	64314041	11	-	27260156	HCC44	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.20713238492808872	[368]	[352,277,491,353]	-3	hSpCas9	negative selection	6818517
64315233	64315256	11	+	27260156	HCC44	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.12470717618293159	[341]	[452,252,525,240]	-2	hSpCas9	negative selection	6818518
64314042	64314065	11	-	27260156	HCC44	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.1925933124351762	[1268]	[1353,1291,1393,1008]	-3	hSpCas9	negative selection	6818519
64314228	64314251	11	+	27260156	G402	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.4111529286388339	[388]	[432,614,1031,422]	5	hSpCas9	negative selection	6875503
64315257	64315280	11	-	27260156	G402	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.21591161000043138	[374]	[806,385,598,370]	2	hSpCas9	negative selection	6875504
64314797	64314820	11	+	27260156	G402	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.8464891725460602	[367]	[277,97,426,192]	-7	hSpCas9	negative selection	6875505
64314018	64314041	11	-	27260156	G402	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.27596798577615034	[368]	[641,728,260,569]	3	hSpCas9	negative selection	6939768
64315233	64315256	11	+	27260156	G402	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.05196903765469352	[341]	[534,348,345,394]	0	hSpCas9	negative selection	6939769
64314042	64314065	11	-	27260156	G402	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.24205105428669005	[1268]	[1546,1190,1541,994]	-3	hSpCas9	negative selection	6939770
64314228	64314251	11	+	27260156	L33	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	-0.07664880019260867	[388]	[386,147,206,396]	-2	hSpCas9	negative selection	6996754
64315257	64315280	11	-	27260156	L33	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5549417848672702	[374]	[561,233,382,461]	9	hSpCas9	negative selection	6996755
64314797	64314820	11	+	27260156	L33	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.010943821086301153	[367]	[407,154,194,362]	0	hSpCas9	negative selection	6996756
64314018	64314041	11	-	27260156	L33	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.07887967573574522	[368]	[329,135,250,336]	-2	hSpCas9	negative selection	7061019
64315233	64315256	11	+	27260156	L33	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.40829876998738235	[341]	[279,99,183,213]	-7	hSpCas9	negative selection	7061020
64314042	64314065	11	-	27260156	L33	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.030220822860866692	[1268]	[1137,572,746,1247]	0	hSpCas9	negative selection	7061021
64314228	64314251	11	+	27260156	K562	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	1.025544749484486	[388]	[713,846,764,512]	9	hSpCas9	negative selection	7118005
64315257	64315280	11	-	27260156	K562	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5934138099128266	[374]	[607,521,430,459]	7	hSpCas9	negative selection	7118006
64314797	64314820	11	+	27260156	K562	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.16605096153018634	[367]	[305,218,273,353]	-2	hSpCas9	negative selection	7118007
64314018	64314041	11	-	27260156	K562	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.4034358858511413	[368]	[458,685,412,213]	5	hSpCas9	negative selection	7182270
64315233	64315256	11	+	27260156	K562	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.6178922762368747	[341]	[289,378,545,609]	7	hSpCas9	negative selection	7182271
64314042	64314065	11	-	27260156	K562	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	0.07380753577667032	[1268]	[1519,976,1367,918]	0	hSpCas9	negative selection	7182272
64314228	64314251	11	+	27260156	HT29	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.40635515411898804	[388]	[655,610,571,659]	7	hSpCas9	negative selection	7239256
64315257	64315280	11	-	27260156	HT29	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.06536010817169419	[374]	[489,397,430,422]	-1	hSpCas9	negative selection	7239257
64314797	64314820	11	+	27260156	HT29	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.39844597972930745	[367]	[415,354,311,285]	-6	hSpCas9	negative selection	7239258
64314018	64314041	11	-	27260156	HT29	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.18463275191130968	[368]	[513,530,548,450]	3	hSpCas9	negative selection	7303521
64315233	64315256	11	+	27260156	HT29	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.09311675489040272	[341]	[304,379,385,467]	-2	hSpCas9	negative selection	7303522
64314042	64314065	11	-	27260156	HT29	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.25452569593817764	[1268]	[1373,1497,1193,1139]	-5	hSpCas9	negative selection	7303523
64314228	64314251	11	+	27260156	MHHES1	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.573941696979374	[388]	[647,832,526,611]	8	hSpCas9	negative selection	7360507
64315257	64315280	11	-	27260156	MHHES1	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5570435981215064	[374]	[820,731,590,411]	8	hSpCas9	negative selection	7360508
64314797	64314820	11	+	27260156	MHHES1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.477676416351348	[367]	[426,266,261,250]	-7	hSpCas9	negative selection	7360509
64314018	64314041	11	-	27260156	MHHES1	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.029977920390843737	[368]	[395,598,371,295]	0	hSpCas9	negative selection	7424772
64315233	64315256	11	+	27260156	MHHES1	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.056235085170831534	[341]	[360,341,363,395]	-1	hSpCas9	negative selection	7424773
64314042	64314065	11	-	27260156	MHHES1	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.09088592153176256	[1268]	[1453,1395,1261,1261]	-2	hSpCas9	negative selection	7424774
64314228	64314251	11	+	27260156	MEWO	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.41969380596989164	[388]	[508,410,544]	8	hSpCas9	negative selection	7481758
64315257	64315280	11	-	27260156	MEWO	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.20311607590807454	[374]	[491,323,412]	4	hSpCas9	negative selection	7481759
64314797	64314820	11	+	27260156	MEWO	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.017958457034829456	[367]	[299,410,324]	0	hSpCas9	negative selection	7481760
64314018	64314041	11	-	27260156	MEWO	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.05229126143286511	[368]	[496,232,300]	-1	hSpCas9	negative selection	7546023
64315233	64315256	11	+	27260156	MEWO	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.029310131143660934	[341]	[314,271,353]	0	hSpCas9	negative selection	7546024
64314042	64314065	11	-	27260156	MEWO	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.11438456022512922	[1268]	[1262,1130,927]	-2	hSpCas9	negative selection	7546025
64314228	64314251	11	+	27260156	LNCAPCLONEFGC	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5407540342111412	[388]	[459,499,559,538]	8	hSpCas9	negative selection	7603009
64315257	64315280	11	-	27260156	LNCAPCLONEFGC	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.014504681369649164	[374]	[369,277,308,413]	0	hSpCas9	negative selection	7603010
64314797	64314820	11	+	27260156	LNCAPCLONEFGC	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.38119438628168495	[367]	[349,243,251,175]	-5	hSpCas9	negative selection	7603011
64314018	64314041	11	-	27260156	LNCAPCLONEFGC	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.17221503409683392	[368]	[354,297,457,412]	2	hSpCas9	negative selection	7667274
64315233	64315256	11	+	27260156	LNCAPCLONEFGC	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.2530003188439558	[341]	[539,268,410,265]	4	hSpCas9	negative selection	7667275
64314042	64314065	11	-	27260156	LNCAPCLONEFGC	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	0.1009517040365222	[1268]	[1199,1246,1311,1182]	1	hSpCas9	negative selection	7667276
64314228	64314251	11	+	27260156	PANC0327	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.25911683512669126	[388]	[599,323,446,309]	4	hSpCas9	negative selection	7724260
64315257	64315280	11	-	27260156	PANC0327	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.3569299990316183	[374]	[599,375,353,396]	5	hSpCas9	negative selection	7724261
64314797	64314820	11	+	27260156	PANC0327	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.883285294365669	[367]	[152,229,152,163]	-8	hSpCas9	negative selection	7724262
64314018	64314041	11	-	27260156	PANC0327	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.3609416422570729	[368]	[600,317,499,292]	5	hSpCas9	negative selection	7788525
64315233	64315256	11	+	27260156	PANC0327	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.36776166692885126	[341]	[364,89,208,306]	-5	hSpCas9	negative selection	7788526
64314042	64314065	11	-	27260156	PANC0327	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.3913621197744557	[1268]	[738,645,889,1179]	-5	hSpCas9	negative selection	7788527
64314228	64314251	11	+	27260156	NCIH2009	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.6996131548668196	[388]	[996,888,782]	8	hSpCas9	negative selection	7845511
64315257	64315280	11	-	27260156	NCIH2009	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.9606076737755256	[374]	[1516,771,870]	9	hSpCas9	negative selection	7845512
64314797	64314820	11	+	27260156	NCIH2009	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.5025511149661411	[367]	[820,358,1028]	7	hSpCas9	negative selection	7845513
64314018	64314041	11	-	27260156	NCIH2009	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.6003699414652741	[368]	[869,672,819]	8	hSpCas9	negative selection	7909776
64315233	64315256	11	+	27260156	NCIH2009	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.25750384835617013	[341]	[438,357,409]	-4	hSpCas9	negative selection	7909777
64314042	64314065	11	-	27260156	NCIH2009	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	0.42502244083216434	[1268]	[2753,2546,1906]	6	hSpCas9	negative selection	7909778
64314228	64314251	11	+	27260156	NCIH1373	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.3636789023126577	[388]	[257,762,642,131]	3	hSpCas9	negative selection	7966762
64315257	64315280	11	-	27260156	NCIH1373	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.24090177215169584	[374]	[584,805,254,81]	2	hSpCas9	negative selection	7966763
64314797	64314820	11	+	27260156	NCIH1373	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-1.6087816057747666	[367]	[143,110,123,43]	-9	hSpCas9	negative selection	7966764
64314018	64314041	11	-	27260156	NCIH1373	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.5372116844443116	[368]	[618,816,281,175]	5	hSpCas9	negative selection	8031027
64315233	64315256	11	+	27260156	NCIH1373	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.07933761393857763	[341]	[370,502,416,79]	0	hSpCas9	negative selection	8031028
64314042	64314065	11	-	27260156	NCIH1373	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.22156488008401043	[1268]	[1879,1147,810,301]	-2	hSpCas9	negative selection	8031029
64314228	64314251	11	+	27260156	PATU8902	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.9587577929948086	[388]	[724,989,941,1650]	9	hSpCas9	negative selection	8088013
64315257	64315280	11	-	27260156	PATU8902	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.7648140218212345	[374]	[566,300,154,230]	-6	hSpCas9	negative selection	8088014
64314797	64314820	11	+	27260156	PATU8902	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.797088983725093	[367]	[417,165,249,360]	-6	hSpCas9	negative selection	8088015
64314018	64314041	11	-	27260156	PATU8902	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.295415717435512	[368]	[654,749,283,957]	3	hSpCas9	negative selection	8152278
64315233	64315256	11	+	27260156	PATU8902	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.431038438909992	[341]	[841,591,579,551]	4	hSpCas9	negative selection	8152279
64314042	64314065	11	-	27260156	PATU8902	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.110994333463311	[1268]	[1437,2364,892,2088]	-1	hSpCas9	negative selection	8152280
64314228	64314251	11	+	27260156	PANC1	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.47681257282361517	[388]	[673,314,521,328]	7	hSpCas9	negative selection	8209264
64315257	64315280	11	-	27260156	PANC1	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5454981525427427	[374]	[496,582,442,385]	8	hSpCas9	negative selection	8209265
64314797	64314820	11	+	27260156	PANC1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.5313798616776189	[367]	[181,326,167,216]	-7	hSpCas9	negative selection	8209266
64314018	64314041	11	-	27260156	PANC1	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.07617090933065879	[368]	[311,346,323,234]	-1	hSpCas9	negative selection	8273529
64315233	64315256	11	+	27260156	PANC1	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.016271661618292743	[341]	[275,234,339,316]	0	hSpCas9	negative selection	8273530
64314042	64314065	11	-	27260156	PANC1	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.1485384102440357	[1268]	[1010,1285,1059,673]	-2	hSpCas9	negative selection	8273531
64314228	64314251	11	+	27260156	PANC0813	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.35582093678607934	[388]	[806,587,556,415]	6	hSpCas9	negative selection	8330515
64315257	64315280	11	-	27260156	PANC0813	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5041946595186856	[374]	[733,616,674,489]	7	hSpCas9	negative selection	8330516
64314797	64314820	11	+	27260156	PANC0813	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.05151526337286655	[367]	[480,496,370,444]	0	hSpCas9	negative selection	8330517
64314018	64314041	11	-	27260156	PANC0813	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.15100041080189153	[368]	[495,396,370,310]	-2	hSpCas9	negative selection	8394780
64315233	64315256	11	+	27260156	PANC0813	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.12089125892285957	[341]	[515,449,272,509]	2	hSpCas9	negative selection	8394781
64314042	64314065	11	-	27260156	PANC0813	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.07338940642268033	[1268]	[2009,1192,1340,1187]	-1	hSpCas9	negative selection	8394782
64314228	64314251	11	+	27260156	RDES	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5181907786935358	[388]	[566,589,667,756]	8	hSpCas9	negative selection	8451766
64315257	64315280	11	-	27260156	RDES	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.5807226192498263	[374]	[511,620,601,892]	8	hSpCas9	negative selection	8451767
64314797	64314820	11	+	27260156	RDES	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.5266596343760546	[367]	[264,246,340,330]	-7	hSpCas9	negative selection	8451768
64314018	64314041	11	-	27260156	RDES	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.51536615510794	[368]	[461,623,582,796]	7	hSpCas9	negative selection	8516031
64315233	64315256	11	+	27260156	RDES	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.0718808481425049	[341]	[307,434,491,432]	1	hSpCas9	negative selection	8516032
64314042	64314065	11	-	27260156	RDES	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.25446614426319214	[1268]	[1074,1147,1153,1566]	-4	hSpCas9	negative selection	8516033
64314228	64314251	11	+	27260156	PC3	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.2088832083871787	[388]	[300,445,756,425]	4	hSpCas9	negative selection	8573017
64315257	64315280	11	-	27260156	PC3	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.47888392209922154	[374]	[361,389,848,637]	8	hSpCas9	negative selection	8573018
64314797	64314820	11	+	27260156	PC3	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.18884629117135404	[367]	[202,268,616,337]	-4	hSpCas9	negative selection	8573019
64314018	64314041	11	-	27260156	PC3	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.11889750377693137	[368]	[269,238,833,451]	2	hSpCas9	negative selection	8637282
64315233	64315256	11	+	27260156	PC3	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.030038470926992855	[341]	[203,418,507,349]	0	hSpCas9	negative selection	8637283
64314042	64314065	11	-	27260156	PC3	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.11937242303329687	[1268]	[731,1231,1853,1179]	-3	hSpCas9	negative selection	8637284
64314228	64314251	11	+	27260156	PATU8988T	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.20878110187307075	[388]	[443,385,434,470]	3	hSpCas9	negative selection	8694268
64315257	64315280	11	-	27260156	PATU8988T	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.6893183149993127	[374]	[415,536,526,876]	9	hSpCas9	negative selection	8694269
64314797	64314820	11	+	27260156	PATU8988T	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.15198516436214354	[367]	[124,485,373,308]	-3	hSpCas9	negative selection	8694270
64314018	64314041	11	-	27260156	PATU8988T	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.01651698360086945	[368]	[440,370,328,297]	0	hSpCas9	negative selection	8758533
64315233	64315256	11	+	27260156	PATU8988T	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.36788283879615213	[341]	[275,278,264,201]	-6	hSpCas9	negative selection	8758534
64314042	64314065	11	-	27260156	PATU8988T	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.35120187760405064	[1268]	[864,819,1178,964]	-5	hSpCas9	negative selection	8758535
64314228	64314251	11	+	27260156	T47D	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.46814263919895116	[388]	[539,640,689,633]	8	hSpCas9	negative selection	8815519
64315257	64315280	11	-	27260156	T47D	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.42195118083146416	[374]	[631,595,428,688]	8	hSpCas9	negative selection	8815520
64314797	64314820	11	+	27260156	T47D	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.4759436170146271	[367]	[279,319,251,382]	-7	hSpCas9	negative selection	8815521
64314018	64314041	11	-	27260156	T47D	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.27434642438045126	[368]	[572,391,594,529]	6	hSpCas9	negative selection	8879784
64315233	64315256	11	+	27260156	T47D	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.1530183875843779	[341]	[372,338,401,318]	-3	hSpCas9	negative selection	8879785
64314042	64314065	11	-	27260156	T47D	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.299789571565537	[1268]	[1159,1175,1276,1190]	-6	hSpCas9	negative selection	8879786
64314228	64314251	11	+	27260156	SU8686	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.08090618955473047	[388]	[424,368,419,419]	1	hSpCas9	negative selection	8936770
64315257	64315280	11	-	27260156	SU8686	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.6734415176840594	[374]	[579,537,623,642]	9	hSpCas9	negative selection	8936771
64314797	64314820	11	+	27260156	SU8686	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.07449714948616981	[367]	[319,386,292,385]	-1	hSpCas9	negative selection	8936772
64314018	64314041	11	-	27260156	SU8686	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.19783551441130431	[368]	[310,260,367,347]	-3	hSpCas9	negative selection	9001035
64315233	64315256	11	+	27260156	SU8686	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.3171157987724603	[341]	[187,228,353,344]	-5	hSpCas9	negative selection	9001036
64314042	64314065	11	-	27260156	SU8686	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.0517582595301731	[1268]	[1255,944,1072,1672]	-1	hSpCas9	negative selection	9001037
64314228	64314251	11	+	27260156	SKES1	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.3501961897418492	[388]	[614,547,501,348]	7	hSpCas9	negative selection	9058021
64315257	64315280	11	-	27260156	SKES1	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.253831786517642	[374]	[588,451,296,461]	5	hSpCas9	negative selection	9058022
64314797	64314820	11	+	27260156	SKES1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.12109280601775363	[367]	[377,558,298,376]	2	hSpCas9	negative selection	9058023
64314018	64314041	11	-	27260156	SKES1	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	-0.18953776062870187	[368]	[363,281,220,411]	-4	hSpCas9	negative selection	9122286
64315233	64315256	11	+	27260156	SKES1	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.1072471302255853	[341]	[428,352,246,261]	-2	hSpCas9	negative selection	9122287
64314042	64314065	11	-	27260156	SKES1	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.18021180504130863	[1268]	[1123,1305,1059,1004]	-4	hSpCas9	negative selection	9122288
64314228	64314251	11	+	27260156	TOV112D	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.5271537712855572	[388]	[448,662,463,680]	8	hSpCas9	negative selection	9179272
64315257	64315280	11	-	27260156	TOV112D	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.023357184896073357	[374]	[386,603,267,323]	0	hSpCas9	negative selection	9179273
64314797	64314820	11	+	27260156	TOV112D	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.4030370457834837	[367]	[188,421,281,249]	-7	hSpCas9	negative selection	9179274
64314018	64314041	11	-	27260156	TOV112D	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.15761147219243435	[368]	[418,685,372,242]	3	hSpCas9	negative selection	9243537
64315233	64315256	11	+	27260156	TOV112D	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.09498909296537289	[341]	[444,248,283,459]	1	hSpCas9	negative selection	9243538
64314042	64314065	11	-	27260156	TOV112D	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.08125182356437333	[1268]	[1260,1199,1248,1100]	-1	hSpCas9	negative selection	9243539
64314228	64314251	11	+	27260156	TC71	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.22636714565422636	[388]	[478,408,638,414]	5	hSpCas9	negative selection	9300523
64315257	64315280	11	-	27260156	TC71	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.4044874924122867	[374]	[483,668,417,563]	8	hSpCas9	negative selection	9300524
64314797	64314820	11	+	27260156	TC71	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.23542800248437484	[367]	[306,377,314,341]	-6	hSpCas9	negative selection	9300525
64314018	64314041	11	-	27260156	TC71	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.09519480531059105	[368]	[337,509,480,356]	2	hSpCas9	negative selection	9364788
64315233	64315256	11	+	27260156	TC71	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	-0.4974743892459338	[341]	[272,266,259,236]	-8	hSpCas9	negative selection	9364789
64314042	64314065	11	-	27260156	TC71	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.08122957984382473	[1268]	[1129,1379,1264,1377]	-2	hSpCas9	negative selection	9364790
64314228	64314251	11	+	27260156	TC32	viability	CACAATTCAAGGAGTGCGCCTGG	ESRRA	ENSG00000173153	0.7221109959658587	[388]	[604,385,845,667]	9	hSpCas9	negative selection	9421774
64315257	64315280	11	-	27260156	TC32	viability	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.47346631869996453	[374]	[357,394,682,583]	7	hSpCas9	negative selection	9421775
64314797	64314820	11	+	27260156	TC32	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.454016641053316	[367]	[224,64,443,378]	-7	hSpCas9	negative selection	9421776
64314018	64314041	11	-	27260156	TC32	viability	ACTTGGTGAAGCGGCAGGCCTGG	ESRRA	ENSG00000173153	0.08460445385376475	[368]	[300,191,564,510]	1	hSpCas9	negative selection	9486039
64315233	64315256	11	+	27260156	TC32	viability	GTATGTTCTACTAAAGGCCTTGG	ESRRA	ENSG00000173153	0.2486432696955442	[341]	[449,217,470,437]	4	hSpCas9	negative selection	9486040
64314042	64314065	11	-	27260156	TC32	viability	CCTTGAGCATGCCCACCCGCAGG	ESRRA	ENSG00000173153	-0.09915627191919585	[1268]	[1074,645,1376,1544]	-2	hSpCas9	negative selection	9486041
64314045	64314068	11	+	27869803	HPAFII	viability after 27 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9542887
64314270	64314293	11	+	27869803	HPAFII	viability after 27 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	1.0993258914423847	[191]	[152,268,NaN]	8	hSpCas9	negative selection	9542888
64314273	64314296	11	+	27869803	HPAFII	viability after 27 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.45103481487455865	[105]	[37,107,NaN]	3	hSpCas9	negative selection	9542889
64314354	64314377	11	-	27869803	HPAFII	viability after 27 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-2.2495872869477473	[235]	[48,6,NaN]	-8	hSpCas9	negative selection	9542890
64315256	64315279	11	-	27869803	HPAFII	viability after 27 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-3.263120028258276	[336]	[18,17,NaN]	-9	hSpCas9	negative selection	9542891
64315257	64315280	11	-	27869803	HPAFII	viability after 27 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.25871192708062596	[823]	[336,382,NaN]	-2	hSpCas9	negative selection	9542892
64314045	64314068	11	+	27869803	HPAFII	viability after 15 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9625336
64314270	64314293	11	+	27869803	HPAFII	viability after 15 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	0.2653725789127076	[191]	[276,229,NaN]	3	hSpCas9	negative selection	9625337
64314273	64314296	11	+	27869803	HPAFII	viability after 15 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.5652998826009261	[105]	[191,153,NaN]	6	hSpCas9	negative selection	9625338
64314354	64314377	11	-	27869803	HPAFII	viability after 15 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.8802925437641776	[235]	[204,95,NaN]	-7	hSpCas9	negative selection	9625339
64315256	64315279	11	-	27869803	HPAFII	viability after 15 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-1.9779594128485471	[336]	[160,48,NaN]	-9	hSpCas9	negative selection	9625340
64315257	64315280	11	-	27869803	HPAFII	viability after 15 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.09319122830816107	[823]	[1149,816,NaN]	1	hSpCas9	negative selection	9625341
64314045	64314068	11	+	27869803	ASPC1	viability after 36 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-1.8555547515517397	[1360]	[163,168,76]	-9	hSpCas9	negative selection	9707785
64314270	64314293	11	+	27869803	ASPC1	viability after 36 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-2.0653956749318976	[333]	[0,45,31]	-9	hSpCas9	negative selection	9707786
64314273	64314296	11	+	27869803	ASPC1	viability after 36 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.5617254188932732	[253]	[175,0,24]	-5	hSpCas9	negative selection	9707787
64314354	64314377	11	-	27869803	ASPC1	viability after 36 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.23654504400239873	[630]	[405,107,93]	-2	hSpCas9	negative selection	9707788
64315256	64315279	11	-	27869803	ASPC1	viability after 36 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-1.5076113477790725	[900]	[140,106,90]	-8	hSpCas9	negative selection	9707789
64315257	64315280	11	-	27869803	ASPC1	viability after 36 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.546314868047663	[1995]	[1423,1045,698]	5	hSpCas9	negative selection	9707790
64314045	64314068	11	+	27869803	PATU8988S	viability after 35 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.007362728749896963	[1235]	[651,347,NaN]	0	hSpCas9	negative selection	9790234
64314270	64314293	11	+	27869803	PATU8988S	viability after 35 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-1.063649234272586	[424]	[33,129,NaN]	-7	hSpCas9	negative selection	9790235
64314273	64314296	11	+	27869803	PATU8988S	viability after 35 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.30720109278870356	[349]	[81,145,NaN]	-3	hSpCas9	negative selection	9790236
64314354	64314377	11	-	27869803	PATU8988S	viability after 35 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.21515381395841338	[532]	[151,217,NaN]	-2	hSpCas9	negative selection	9790237
64315256	64315279	11	-	27869803	PATU8988S	viability after 35 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-1.0222420730227169	[624]	[94,152,NaN]	-7	hSpCas9	negative selection	9790238
64315257	64315280	11	-	27869803	PATU8988S	viability after 35 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.35382355854535796	[1391]	[694,737,NaN]	4	hSpCas9	negative selection	9790239
64314045	64314068	11	+	27869803	PATU8988S	viability after 31 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.0942962700595038	[1235]	[603,426,NaN]	1	hSpCas9	negative selection	9872683
64314270	64314293	11	+	27869803	PATU8988S	viability after 31 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	-1.251974928995058	[424]	[42,106,NaN]	-8	hSpCas9	negative selection	9872684
64314273	64314296	11	+	27869803	PATU8988S	viability after 31 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.08481773596956577	[349]	[91,181,NaN]	-1	hSpCas9	negative selection	9872685
64314354	64314377	11	-	27869803	PATU8988S	viability after 31 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-0.10688447096103881	[532]	[166,235,NaN]	-1	hSpCas9	negative selection	9872686
64315256	64315279	11	-	27869803	PATU8988S	viability after 31 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.708890841981301	[624]	[89,231,NaN]	-6	hSpCas9	negative selection	9872687
64315257	64315280	11	-	27869803	PATU8988S	viability after 31 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	0.508515961751627	[1391]	[632,988,NaN]	6	hSpCas9	negative selection	9872688
64314045	64314068	11	+	27869803	HPAFII	viability after 35 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	9955132
64314270	64314293	11	+	27869803	HPAFII	viability after 35 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	1.9461991773308165	[191]	[208,560,NaN]	9	hSpCas9	negative selection	9955133
64314273	64314296	11	+	27869803	HPAFII	viability after 35 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	-0.4393829005725025	[105]	[8,73,NaN]	-3	hSpCas9	negative selection	9955134
64314354	64314377	11	-	27869803	HPAFII	viability after 35 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-3.0745838961402154	[235]	[24,1,NaN]	-8	hSpCas9	negative selection	9955135
64315256	64315279	11	-	27869803	HPAFII	viability after 35 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-3.110085991195971	[336]	[7,32,NaN]	-8	hSpCas9	negative selection	9955136
64315257	64315280	11	-	27869803	HPAFII	viability after 35 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.39065062207337786	[823]	[233,412,NaN]	-2	hSpCas9	negative selection	9955137
64314045	64314068	11	+	27869803	HPAFII	viability after 31 days	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10037581
64314270	64314293	11	+	27869803	HPAFII	viability after 31 days	GCAGAAGTACAAGCGGCGGCCGG	ESRRA	ENSG00000173153	1.5686935045799337	[191]	[76,583,NaN]	9	hSpCas9	negative selection	10037582
64314273	64314296	11	+	27869803	HPAFII	viability after 31 days	GAAGTACAAGCGGCGGCCGGAGG	ESRRA	ENSG00000173153	0.19321664172343	[105]	[45,91,NaN]	1	hSpCas9	negative selection	10037583
64314354	64314377	11	-	27869803	HPAFII	viability after 31 days	TGCTCTCACCTGTCTTCCGGGGG	ESRRA	ENSG00000173153	-2.182787715753749	[235]	[32,24,NaN]	-8	hSpCas9	negative selection	10037584
64315256	64315279	11	-	27869803	HPAFII	viability after 31 days	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-2.293772906513374	[336]	[28,48,NaN]	-8	hSpCas9	negative selection	10037585
64315257	64315280	11	-	27869803	HPAFII	viability after 31 days	CAGACTCACCTGAATTGGCAAGG	ESRRA	ENSG00000173153	-0.6745000419599803	[823]	[216,368,NaN]	-4	hSpCas9	negative selection	10037586
64314266	64314289	11	+	28162770	P31FUJ	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	0.33604063094350045	[59]	[88]	3	hSpCas9	negative selection	10151497
64307263	64307286	11	+	28162770	P31FUJ	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.6782133527367413	[383]	[281]	-5	hSpCas9	negative selection	10151498
64314276	64314299	11	+	28162770	P31FUJ	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.05222995877255787	[74]	[84]	0	hSpCas9	negative selection	10151499
64307292	64307315	11	-	28162770	P31FUJ	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.9808229870895806	[130]	[38]	-8	hSpCas9	negative selection	10151500
64314045	64314068	11	+	28162770	P31FUJ	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.012836520472470803	[169]	[197]	0	hSpCas9	negative selection	10151501
64314797	64314820	11	+	28162770	P31FUJ	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.09139606409781084	[253]	[317]	0	hSpCas9	negative selection	10151502
64307307	64307330	11	-	28162770	P31FUJ	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.4625366010919945	[196]	[41]	-8	hSpCas9	negative selection	10151503
64314813	64314836	11	-	28162770	P31FUJ	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.29228884032937885	[122]	[176]	3	hSpCas9	negative selection	10151504
64315181	64315204	11	+	28162770	P31FUJ	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.3897046651669127	[353]	[544]	4	hSpCas9	negative selection	10151505
64315256	64315279	11	-	28162770	P31FUJ	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.0033203582916112584	[405]	[475]	0	hSpCas9	negative selection	10151506
64314266	64314289	11	+	28162770	TF1	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10320863
64307263	64307286	11	+	28162770	TF1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10320864
64314276	64314299	11	+	28162770	TF1	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10320865
64307292	64307315	11	-	28162770	TF1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10320866
64314045	64314068	11	+	28162770	TF1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10320867
64314797	64314820	11	+	28162770	TF1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10320868
64307307	64307330	11	-	28162770	TF1	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10320869
64314813	64314836	11	-	28162770	TF1	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	NaN	[NaN]	[214]	1	hSpCas9	negative selection	10320870
64315181	64315204	11	+	28162770	TF1	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10320871
64315256	64315279	11	-	28162770	TF1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10320872
64314266	64314289	11	+	28162770	SKM1	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.8220016980220053	[15]	[15]	-6	hSpCas9	negative selection	10490229
64307263	64307286	11	+	28162770	SKM1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.3435388186015279	[88]	[123]	-3	hSpCas9	negative selection	10490230
64314276	64314299	11	+	28162770	SKM1	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-1.1115083152169905	[32]	[26]	-7	hSpCas9	negative selection	10490231
64307292	64307315	11	-	28162770	SKM1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-0.48639866623756656	[41]	[52]	-4	hSpCas9	negative selection	10490232
64314045	64314068	11	+	28162770	SKM1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.4357960594456414	[45]	[219]	9	hSpCas9	negative selection	10490233
64314797	64314820	11	+	28162770	SKM1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.8784380201190867	[59]	[194]	8	hSpCas9	negative selection	10490234
64307307	64307330	11	-	28162770	SKM1	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.7492453555866916	[57]	[60]	-5	hSpCas9	negative selection	10490235
64314813	64314836	11	-	28162770	SKM1	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-0.3074285251922473	[27]	[39]	-3	hSpCas9	negative selection	10490236
64315181	64315204	11	+	28162770	SKM1	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.115048672922239	[67]	[110]	-1	hSpCas9	negative selection	10490237
64315256	64315279	11	-	28162770	SKM1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.25857235885049074	[89]	[132]	-2	hSpCas9	negative selection	10490238
64314266	64314289	11	+	28162770	SKM1	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.8220016980220053	[15]	[15]	-6	hSpCas9	negative selection	10659595
64307263	64307286	11	+	28162770	SKM1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.3435388186015279	[88]	[123]	-3	hSpCas9	negative selection	10659596
64314276	64314299	11	+	28162770	SKM1	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-1.1115083152169905	[32]	[26]	-7	hSpCas9	negative selection	10659597
64307292	64307315	11	-	28162770	SKM1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-0.48639866623756656	[41]	[52]	-4	hSpCas9	negative selection	10659598
64314045	64314068	11	+	28162770	SKM1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.4357960594456414	[45]	[219]	9	hSpCas9	negative selection	10659599
64314797	64314820	11	+	28162770	SKM1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.8784380201190867	[59]	[194]	8	hSpCas9	negative selection	10659600
64307307	64307330	11	-	28162770	SKM1	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.7492453555866916	[57]	[60]	-5	hSpCas9	negative selection	10659601
64314813	64314836	11	-	28162770	SKM1	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-0.3074285251922473	[27]	[39]	-3	hSpCas9	negative selection	10659602
64315181	64315204	11	+	28162770	SKM1	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.115048672922239	[67]	[110]	-1	hSpCas9	negative selection	10659603
64315256	64315279	11	-	28162770	SKM1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.25857235885049074	[89]	[132]	-2	hSpCas9	negative selection	10659604
64314266	64314289	11	+	28162770	PL21	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-1.8778628975119531	[75]	[8]	-8	hSpCas9	negative selection	10828961
64307263	64307286	11	+	28162770	PL21	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	0.3600805273590104	[289]	[161]	3	hSpCas9	negative selection	10828962
64314276	64314299	11	+	28162770	PL21	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	1.8375695351046122	[62]	[97]	9	hSpCas9	negative selection	10828963
64307292	64307315	11	-	28162770	PL21	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-0.9536657215897153	[177]	[39]	-6	hSpCas9	negative selection	10828964
64314045	64314068	11	+	28162770	PL21	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.2369241911195226	[175]	[64]	-2	hSpCas9	negative selection	10828965
64314797	64314820	11	+	28162770	PL21	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.28420387927779456	[299]	[158]	2	hSpCas9	negative selection	10828966
64307307	64307330	11	-	28162770	PL21	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.1374417447095277	[138]	[54]	-1	hSpCas9	negative selection	10828967
64314813	64314836	11	-	28162770	PL21	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	1.7791528488792898	[80]	[120]	9	hSpCas9	negative selection	10828968
64315181	64315204	11	+	28162770	PL21	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.1196496966289522	[257]	[121]	1	hSpCas9	negative selection	10828969
64315256	64315279	11	-	28162770	PL21	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.14121901034694373	[298]	[117]	-1	hSpCas9	negative selection	10828970
64314266	64314289	11	+	28162770	P31FUJ	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	0.33604063094350045	[59]	[88]	3	hSpCas9	negative selection	10998327
64307263	64307286	11	+	28162770	P31FUJ	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.6782133527367413	[383]	[281]	-5	hSpCas9	negative selection	10998328
64314276	64314299	11	+	28162770	P31FUJ	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.05222995877255787	[74]	[84]	0	hSpCas9	negative selection	10998329
64307292	64307315	11	-	28162770	P31FUJ	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.9808229870895806	[130]	[38]	-8	hSpCas9	negative selection	10998330
64314045	64314068	11	+	28162770	P31FUJ	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.012836520472470803	[169]	[197]	0	hSpCas9	negative selection	10998331
64314797	64314820	11	+	28162770	P31FUJ	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.09139606409781084	[253]	[317]	0	hSpCas9	negative selection	10998332
64307307	64307330	11	-	28162770	P31FUJ	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.4625366010919945	[196]	[41]	-8	hSpCas9	negative selection	10998333
64314813	64314836	11	-	28162770	P31FUJ	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.29228884032937885	[122]	[176]	3	hSpCas9	negative selection	10998334
64315181	64315204	11	+	28162770	P31FUJ	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.3897046651669127	[353]	[544]	4	hSpCas9	negative selection	10998335
64315256	64315279	11	-	28162770	P31FUJ	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	-0.0033203582916112584	[405]	[475]	0	hSpCas9	negative selection	10998336
64314266	64314289	11	+	28162770	OCIAML5	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.9733728670861309	[61]	[56]	-6	hSpCas9	negative selection	11167693
64307263	64307286	11	+	28162770	OCIAML5	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.7711465754804294	[207]	[219]	-5	hSpCas9	negative selection	11167694
64314276	64314299	11	+	28162770	OCIAML5	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	0.42356787174943067	[37]	[91]	3	hSpCas9	negative selection	11167695
64307292	64307315	11	-	28162770	OCIAML5	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.0999940843075826	[56]	[47]	-6	hSpCas9	negative selection	11167696
64314045	64314068	11	+	28162770	OCIAML5	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.9372544283633455	[45]	[158]	7	hSpCas9	negative selection	11167697
64314797	64314820	11	+	28162770	OCIAML5	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.12692641209458042	[146]	[242]	-1	hSpCas9	negative selection	11167698
64307307	64307330	11	-	28162770	OCIAML5	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.417663746718222	[73]	[24]	-8	hSpCas9	negative selection	11167699
64314813	64314836	11	-	28162770	OCIAML5	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	1.1277555471983727	[53]	[212]	8	hSpCas9	negative selection	11167700
64315181	64315204	11	+	28162770	OCIAML5	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.9747490906388256	[183]	[168]	-6	hSpCas9	negative selection	11167701
64315256	64315279	11	-	28162770	OCIAML5	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.3617485657492314	[240]	[558]	3	hSpCas9	negative selection	11167702
64314266	64314289	11	+	28162770	EOL1	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.7252658735005899	[90]	[28]	-5	hSpCas9	negative selection	11337059
64307263	64307286	11	+	28162770	EOL1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.7285862317922008	[389]	[123]	-5	hSpCas9	negative selection	11337060
64314276	64314299	11	+	28162770	EOL1	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.7357028564548589	[176]	[55]	-5	hSpCas9	negative selection	11337061
64307292	64307315	11	-	28162770	EOL1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.7275289250091588	[307]	[48]	-8	hSpCas9	negative selection	11337062
64314045	64314068	11	+	28162770	EOL1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.19239919370210412	[298]	[179]	1	hSpCas9	negative selection	11337063
64314797	64314820	11	+	28162770	EOL1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.9932931235985247	[528]	[139]	-6	hSpCas9	negative selection	11337064
64307307	64307330	11	-	28162770	EOL1	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.7971510659423613	[187]	[56]	-5	hSpCas9	negative selection	11337065
64314813	64314836	11	-	28162770	EOL1	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	1.7031324549384796	[122]	[210]	9	hSpCas9	negative selection	11337066
64315181	64315204	11	+	28162770	EOL1	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.22410805342944246	[259]	[159]	2	hSpCas9	negative selection	11337067
64315256	64315279	11	-	28162770	EOL1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.024576589901806556	[389]	[208]	0	hSpCas9	negative selection	11337068
64314266	64314289	11	+	28162770	MOLM13	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	0.01772365886213323	[96]	[70]	0	hSpCas9	negative selection	11506425
64307263	64307286	11	+	28162770	MOLM13	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.515157485174224	[422]	[213]	-3	hSpCas9	negative selection	11506426
64314276	64314299	11	+	28162770	MOLM13	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	2.065675922623319	[111]	[338]	9	hSpCas9	negative selection	11506427
64307292	64307315	11	-	28162770	MOLM13	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.713861055294523	[244]	[26]	-8	hSpCas9	negative selection	11506428
64314045	64314068	11	+	28162770	MOLM13	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.6017451282793693	[215]	[473]	9	hSpCas9	negative selection	11506429
64314797	64314820	11	+	28162770	MOLM13	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	1.4520788666971167	[366]	[725]	9	hSpCas9	negative selection	11506430
64307307	64307330	11	-	28162770	MOLM13	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-1.1617421685103055	[163]	[52]	-6	hSpCas9	negative selection	11506431
64314813	64314836	11	-	28162770	MOLM13	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.6333129907519502	[106]	[119]	5	hSpCas9	negative selection	11506432
64315181	64315204	11	+	28162770	MOLM13	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.972034354657408	[360]	[511]	7	hSpCas9	negative selection	11506433
64315256	64315279	11	-	28162770	MOLM13	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.28653877330449307	[617]	[544]	2	hSpCas9	negative selection	11506434
64314266	64314289	11	+	28162770	HEL	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.7442842911088903	[101]	[38]	-5	hSpCas9	negative selection	11675791
64307263	64307286	11	+	28162770	HEL	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.11399001698727934	[342]	[202]	-1	hSpCas9	negative selection	11675792
64314276	64314299	11	+	28162770	HEL	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	0.028028987885148737	[97]	[63]	0	hSpCas9	negative selection	11675793
64307292	64307315	11	-	28162770	HEL	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.921465108554002	[206]	[34]	-7	hSpCas9	negative selection	11675794
64314045	64314068	11	+	28162770	HEL	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	1.3267811064295159	[210]	[338]	9	hSpCas9	negative selection	11675795
64314797	64314820	11	+	28162770	HEL	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.1664825907217008	[344]	[247]	1	hSpCas9	negative selection	11675796
64307307	64307330	11	-	28162770	HEL	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-1.2879985055625292	[121]	[31]	-6	hSpCas9	negative selection	11675797
64314813	64314836	11	-	28162770	HEL	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-0.4067298442639429	[88]	[42]	-3	hSpCas9	negative selection	11675798
64315181	64315204	11	+	28162770	HEL	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	0.5522265390949147	[295]	[277]	4	hSpCas9	negative selection	11675799
64315256	64315279	11	-	28162770	HEL	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.4612343116631614	[515]	[454]	4	hSpCas9	negative selection	11675800
64314266	64314289	11	+	28162770	MV411	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.49540460972010014	[81]	[48]	-4	hSpCas9	negative selection	11845157
64307263	64307286	11	+	28162770	MV411	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-0.5309307423939934	[270]	[157]	-4	hSpCas9	negative selection	11845158
64314276	64314299	11	+	28162770	MV411	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	0.1985279503018288	[89]	[86]	1	hSpCas9	negative selection	11845159
64307292	64307315	11	-	28162770	MV411	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.0055431903870957	[142]	[29]	-8	hSpCas9	negative selection	11845160
64314045	64314068	11	+	28162770	MV411	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.29386372114224113	[178]	[122]	-2	hSpCas9	negative selection	11845161
64314797	64314820	11	+	28162770	MV411	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.10095146230529128	[289]	[261]	0	hSpCas9	negative selection	11845162
64307307	64307330	11	-	28162770	MV411	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.659453044825743	[104]	[13]	-9	hSpCas9	negative selection	11845163
64314813	64314836	11	-	28162770	MV411	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-0.385780118545602	[75]	[48]	-3	hSpCas9	negative selection	11845164
64315181	64315204	11	+	28162770	MV411	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.3974674903946631	[257]	[164]	-3	hSpCas9	negative selection	11845165
64315256	64315279	11	-	28162770	MV411	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.9825404009317921	[309]	[515]	8	hSpCas9	negative selection	11845166
64314266	64314289	11	+	28162770	MONOMAC1	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-2.4865434642545385	[43]	[8]	-9	hSpCas9	negative selection	12014523
64307263	64307286	11	+	28162770	MONOMAC1	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	1.0718981602139244	[182]	[440]	8	hSpCas9	negative selection	12014524
64314276	64314299	11	+	28162770	MONOMAC1	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-1.5051591424218858	[51]	[20]	-8	hSpCas9	negative selection	12014525
64307292	64307315	11	-	28162770	MONOMAC1	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.6781635367961703	[133]	[23]	-9	hSpCas9	negative selection	12014526
64314045	64314068	11	+	28162770	MONOMAC1	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-0.5840599701688008	[101]	[77]	-5	hSpCas9	negative selection	12014527
64314797	64314820	11	+	28162770	MONOMAC1	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	-0.8250680696725958	[169]	[109]	-6	hSpCas9	negative selection	12014528
64307307	64307330	11	-	28162770	MONOMAC1	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-0.3760069881048731	[59]	[52]	-3	hSpCas9	negative selection	12014529
64314813	64314836	11	-	28162770	MONOMAC1	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	-1.2965725206104681	[44]	[20]	-7	hSpCas9	negative selection	12014530
64315181	64315204	11	+	28162770	MONOMAC1	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.44726347659272714	[156]	[131]	-4	hSpCas9	negative selection	12014531
64315256	64315279	11	-	28162770	MONOMAC1	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.626085390856367	[142]	[252]	6	hSpCas9	negative selection	12014532
64314266	64314289	11	+	28162770	OCIAML2	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-0.3897098298585939	[12]	[54]	-3	hSpCas9	negative selection	12183889
64307263	64307286	11	+	28162770	OCIAML2	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	0.2249767391629876	[45]	[297]	2	hSpCas9	negative selection	12183890
64314276	64314299	11	+	28162770	OCIAML2	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	0.6491094190319343	[12]	[112]	6	hSpCas9	negative selection	12183891
64307292	64307315	11	-	28162770	OCIAML2	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-1.0685313816708155	[27]	[73]	-6	hSpCas9	negative selection	12183892
64314045	64314068	11	+	28162770	OCIAML2	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	0.5112228280475796	[29]	[236]	5	hSpCas9	negative selection	12183893
64314797	64314820	11	+	28162770	OCIAML2	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	0.4962033108226394	[43]	[343]	5	hSpCas9	negative selection	12183894
64307307	64307330	11	-	28162770	OCIAML2	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-1.4350059155114399	[19]	[40]	-7	hSpCas9	negative selection	12183895
64314813	64314836	11	-	28162770	OCIAML2	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.6245274077981791	[10]	[93]	6	hSpCas9	negative selection	12183896
64315181	64315204	11	+	28162770	OCIAML2	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.04741839451761731	[43]	[235]	0	hSpCas9	negative selection	12183897
64315256	64315279	11	-	28162770	OCIAML2	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.9516031754408865	[49]	[535]	8	hSpCas9	negative selection	12183898
64314266	64314289	11	+	28162770	OCIAML3	viability	GGCGGCAGAAGTACAAGCGGCGG	ESRRA	ENSG00000173153	-1.7575063726070428	[27]	[24]	-8	hSpCas9	negative selection	12353255
64307263	64307286	11	+	28162770	OCIAML3	viability	GACAGAGACCGAGCCTCCTGTGG	ESRRA	ENSG00000173153	-1.061133650751461	[93]	[135]	-6	hSpCas9	negative selection	12353256
64314276	64314299	11	+	28162770	OCIAML3	viability	GTACAAGCGGCGGCCGGAGGTGG	ESRRA	ENSG00000173153	-0.8439858933325106	[21]	[36]	-6	hSpCas9	negative selection	12353257
64307292	64307315	11	-	28162770	OCIAML3	viability	GCGAGTGGGAGCTGGACCAGGGG	ESRRA	ENSG00000173153	-2.5236183124327654	[39]	[20]	-9	hSpCas9	negative selection	12353258
64314045	64314068	11	+	28162770	OCIAML3	viability	GCGGGTGGGCATGCTCAAGGAGG	ESRRA	ENSG00000173153	-1.066076084639386	[42]	[61]	-6	hSpCas9	negative selection	12353259
64314797	64314820	11	+	28162770	OCIAML3	viability	TATGCCATGCCTGACCCCGCAGG	ESRRA	ENSG00000173153	1.425357684542768	[36]	[299]	9	hSpCas9	negative selection	12353260
64307307	64307330	11	-	28162770	OCIAML3	viability	GTGGCCTGGGAGGCAGCGAGTGG	ESRRA	ENSG00000173153	-2.059671212672975	[57]	[41]	-8	hSpCas9	negative selection	12353261
64314813	64314836	11	-	28162770	OCIAML3	viability	GAGGTGCCCATCAGGGCCTGCGG	ESRRA	ENSG00000173153	0.11871040759536577	[17]	[58]	1	hSpCas9	negative selection	12353262
64315181	64315204	11	+	28162770	OCIAML3	viability	CCCTGCTGCAACTAGTGCGGCGG	ESRRA	ENSG00000173153	-0.933857643208788	[80]	[127]	-6	hSpCas9	negative selection	12353263
64315256	64315279	11	-	28162770	OCIAML3	viability	AGACTCACCTGAATTGGCAAGGG	ESRRA	ENSG00000173153	0.40117534337806104	[74]	[298]	4	hSpCas9	negative selection	12353264