Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 26260
• Symbol: FBXO25
• Description: F-box protein 25

DataSource: http://genomecrispr.dkfz.de/#!/results/FBXO25

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
458493	458516	8	+	26472758	Jiyoye	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.2424928086030982	[341]	[108]	-7	hSpCas9	negative selection	56706
458427	458450	8	+	26472758	Jiyoye	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.3518165189903317	[219]	[129]	-3	hSpCas9	negative selection	56707
458383	458406	8	-	26472758	Jiyoye	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.24671070931262729	[208]	[186]	2	hSpCas9	negative selection	56708
458402	458425	8	-	26472758	Jiyoye	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.8596875862033799	[75]	[103]	6	hSpCas9	negative selection	56709
458449	458472	8	+	26472758	Jiyoye	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.020152258396626266	[305]	[233]	0	hSpCas9	negative selection	56710
463072	463095	8	+	26472758	Jiyoye	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	1.085247286618511	[154]	[247]	7	hSpCas9	negative selection	56711
463104	463127	8	+	26472758	Jiyoye	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-1.794458479663777	[45]	[9]	-8	hSpCas9	negative selection	56712
450016	450039	8	+	26472758	Jiyoye	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.483796663108786	[54]	[57]	3	hSpCas9	negative selection	56713
451432	451455	8	+	26472758	Jiyoye	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	0.608809242675524	[19]	[22]	4	hSpCas9	negative selection	56714
458493	458516	8	+	26472758	KBM7	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.5509776771293586	[1415,1072]	[294,110]	-8	hSpCas9	negative selection	247824
458427	458450	8	+	26472758	KBM7	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.3764657672382586	[637,490]	[404,284]	4	hSpCas9	negative selection	247825
458383	458406	8	-	26472758	KBM7	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.1454173812073894	[844,457]	[326,332]	1	hSpCas9	negative selection	247826
458402	458425	8	-	26472758	KBM7	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.27740964356107034	[428,267]	[234,158]	3	hSpCas9	negative selection	247827
458449	458472	8	+	26472758	KBM7	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.31847747159320994	[1342,1010]	[890,497]	3	hSpCas9	negative selection	247828
463072	463095	8	+	26472758	KBM7	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.03940649560525433	[805,715]	[427,312]	0	hSpCas9	negative selection	247829
463104	463127	8	+	26472758	KBM7	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.5307398860691612	[169,294]	[56,96]	-5	hSpCas9	negative selection	247830
450016	450039	8	+	26472758	KBM7	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.34562715029506974	[362,375]	[264,183]	3	hSpCas9	negative selection	247831
451432	451455	8	+	26472758	KBM7	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-0.41749674818495475	[49,55]	[30,7]	-4	hSpCas9	negative selection	247832
458493	458516	8	+	26472758	Raji	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.0988702391437437	[562]	[60]	-7	hSpCas9	negative selection	438942
458427	458450	8	+	26472758	Raji	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.2152988745404869	[411]	[110]	2	hSpCas9	negative selection	438943
458383	458406	8	-	26472758	Raji	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.6709435593625314	[248]	[91]	6	hSpCas9	negative selection	438944
458402	458425	8	-	26472758	Raji	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.09816500534422079	[156]	[38]	0	hSpCas9	negative selection	438945
458449	458472	8	+	26472758	Raji	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.1172313213299467	[291]	[146]	8	hSpCas9	negative selection	438946
463072	463095	8	+	26472758	Raji	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.9247302290883651	[369]	[162]	8	hSpCas9	negative selection	438947
463104	463127	8	+	26472758	Raji	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.5115262972708945	[85]	[13]	-4	hSpCas9	negative selection	438948
450016	450039	8	+	26472758	Raji	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7951056105199563	[148]	[59]	7	hSpCas9	negative selection	438949
451432	451455	8	+	26472758	Raji	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	2.1073835353735992	[17]	[17]	9	hSpCas9	negative selection	438950
458493	458516	8	+	26472758	K562	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-3.786293629168863	[996]	[60]	-9	hSpCas9	negative selection	630060
458427	458450	8	+	26472758	K562	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.8596094078024745	[550]	[843]	7	hSpCas9	negative selection	630061
458383	458406	8	-	26472758	K562	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.4528988421476407	[520]	[601]	3	hSpCas9	negative selection	630062
458402	458425	8	-	26472758	K562	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	1.3881770671272928	[271]	[600]	9	hSpCas9	negative selection	630063
458449	458472	8	+	26472758	K562	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.8480504398316732	[690]	[1049]	7	hSpCas9	negative selection	630064
463072	463095	8	+	26472758	K562	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	1.1125786735411034	[749]	[1368]	8	hSpCas9	negative selection	630065
463104	463127	8	+	26472758	K562	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	1.6076350310444412	[123]	[318]	9	hSpCas9	negative selection	630066
450016	450039	8	+	26472758	K562	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.5879430513606085	[304]	[386]	5	hSpCas9	negative selection	630067
451432	451455	8	+	26472758	K562	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-0.7097775827204287	[30]	[15]	-4	hSpCas9	negative selection	630068
458431	458454	8	-	26627737	DLD1	viability	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.7266920335238911	[1563]	[370,333,197]	-6	hSpCas9	negative selection	839556
458449	458472	8	+	26627737	DLD1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.432507463666722	[247]	[124,310,197]	9	hSpCas9	negative selection	839557
463072	463095	8	+	26627737	DLD1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.23222760522440522	[878]	[437,196,326]	2	hSpCas9	negative selection	839564
468763	468786	8	-	26627737	DLD1	viability	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.12728234908574	[471]	[479,281,218]	9	hSpCas9	negative selection	839588
458431	458454	8	-	26627737	GBM cells	viability after 5 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.1753958223770551	[736]	[335,363]	-3	hSpCas9	negative selection	921871
458449	458472	8	+	26627737	GBM cells	viability after 5 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.762667967116206	[171]	[118,193]	8	hSpCas9	negative selection	921872
463072	463095	8	+	26627737	GBM cells	viability after 5 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.27607149049344004	[491]	[245,392]	4	hSpCas9	negative selection	921879
468763	468786	8	-	26627737	GBM cells	viability after 5 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.07377877911857911	[313]	[159,159]	-1	hSpCas9	negative selection	921903
458431	458454	8	-	26627737	GBM cells	viability after 13 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.08904905447167244	[736]	[485,375]	1	hSpCas9	negative selection	1004186
458449	458472	8	+	26627737	GBM cells	viability after 13 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.0521925815659237	[171]	[203,184]	9	hSpCas9	negative selection	1004187
463072	463095	8	+	26627737	GBM cells	viability after 13 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.3951273796220014	[491]	[312,381]	5	hSpCas9	negative selection	1004194
468763	468786	8	-	26627737	GBM cells	viability after 13 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.002814721385119623	[313]	[174,165]	0	hSpCas9	negative selection	1004218
458431	458454	8	-	26627737	GBM cells	viability after 21 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.28301700766726956	[736]	[482,490]	3	hSpCas9	negative selection	1086501
458449	458472	8	+	26627737	GBM cells	viability after 21 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.078134441908979	[171]	[213,181]	9	hSpCas9	negative selection	1086502
463072	463095	8	+	26627737	GBM cells	viability after 21 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.1244658370462024	[491]	[305,277]	1	hSpCas9	negative selection	1086509
468763	468786	8	-	26627737	GBM cells	viability after 21 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.39103399689578777	[313]	[218,227]	4	hSpCas9	negative selection	1086533
458431	458454	8	-	26627737	RPE1	viability after 9 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.25332326854645837	[2294]	[373,897]	-2	hSpCas9	negative selection	1168816
458449	458472	8	+	26627737	RPE1	viability after 9 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.7637394371770619	[261]	[54,247]	5	hSpCas9	negative selection	1168817
463072	463095	8	+	26627737	RPE1	viability after 9 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.09262540707304456	[1317]	[494,368]	0	hSpCas9	negative selection	1168824
468763	468786	8	-	26627737	RPE1	viability after 9 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.46190493182191705	[1549]	[412,273]	-3	hSpCas9	negative selection	1168848
458431	458454	8	-	26627737	RPE1	viability after 12 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.24825864647365958	[2294]	[250,802]	-2	hSpCas9	negative selection	1251131
458449	458472	8	+	26627737	RPE1	viability after 12 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.6977462609831397	[261]	[68,161]	4	hSpCas9	negative selection	1251132
463072	463095	8	+	26627737	RPE1	viability after 12 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.648394986005883	[1317]	[657,445]	4	hSpCas9	negative selection	1251139
468763	468786	8	-	26627737	RPE1	viability after 12 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.5877525670370987	[1549]	[398,147]	-4	hSpCas9	negative selection	1251163
458431	458454	8	-	26627737	RPE1	viability after 15 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.46483249915561875	[2294]	[279,653]	-3	hSpCas9	negative selection	1333446
458449	458472	8	+	26627737	RPE1	viability after 15 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.3586280663494688	[261]	[242,138]	7	hSpCas9	negative selection	1333447
463072	463095	8	+	26627737	RPE1	viability after 15 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.8895277420213926	[1317]	[791,592]	5	hSpCas9	negative selection	1333454
468763	468786	8	-	26627737	RPE1	viability after 15 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.5653183100755714	[1549]	[362,231]	-4	hSpCas9	negative selection	1333478
458431	458454	8	-	26627737	RPE1	viability after 18 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.026435279422760694	[2294]	[275,962]	0	hSpCas9	negative selection	1415761
458449	458472	8	+	26627737	RPE1	viability after 18 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	1.205728267492598	[261]	[150,175]	7	hSpCas9	negative selection	1415762
463072	463095	8	+	26627737	RPE1	viability after 18 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	1.12791144953593	[1317]	[1019,517]	6	hSpCas9	negative selection	1415769
468763	468786	8	-	26627737	RPE1	viability after 18 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-0.6289373721699238	[1549]	[415,114]	-4	hSpCas9	negative selection	1415793
458431	458454	8	-	26627737	HeLa	viability after 8 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.15933949556456417	[885]	[648,367,329]	1	hSpCas9	negative selection	1498076
458449	458472	8	+	26627737	HeLa	viability after 8 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.7704181983701568	[450]	[99,69,167]	-6	hSpCas9	negative selection	1498077
463072	463095	8	+	26627737	HeLa	viability after 8 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.12996260373036939	[908]	[544,265,316]	-1	hSpCas9	negative selection	1498084
468763	468786	8	-	26627737	HeLa	viability after 8 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.7720744556989954	[359]	[322,390,111]	6	hSpCas9	negative selection	1498108
458431	458454	8	-	26627737	HeLa	viability after 12 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.09175383303454598	[885]	[386,258,394]	-1	hSpCas9	negative selection	1580391
458449	458472	8	+	26627737	HeLa	viability after 12 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.08618191759071622	[450]	[94,174,322]	0	hSpCas9	negative selection	1580392
463072	463095	8	+	26627737	HeLa	viability after 12 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.24115812415089732	[908]	[438,640,230]	2	hSpCas9	negative selection	1580399
468763	468786	8	-	26627737	HeLa	viability after 12 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.9606974631162977	[359]	[589,113,191]	7	hSpCas9	negative selection	1580423
458431	458454	8	-	26627737	HeLa	viability after 15 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.12707890640063546	[885]	[296,539,341]	1	hSpCas9	negative selection	1662706
458449	458472	8	+	26627737	HeLa	viability after 15 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.12397239050152734	[450]	[164,255,177]	1	hSpCas9	negative selection	1662707
463072	463095	8	+	26627737	HeLa	viability after 15 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.07995684751034293	[908]	[289,574,302]	0	hSpCas9	negative selection	1662714
468763	468786	8	-	26627737	HeLa	viability after 15 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.0264125147944307	[359]	[295,211,394]	7	hSpCas9	negative selection	1662738
458431	458454	8	-	26627737	HeLa	viability after 18 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.13199539147156591	[885]	[201,446,341]	1	hSpCas9	negative selection	1745021
458449	458472	8	+	26627737	HeLa	viability after 18 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.10648369376264519	[450]	[109,206,177]	0	hSpCas9	negative selection	1745022
463072	463095	8	+	26627737	HeLa	viability after 18 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.07526112928043971	[908]	[188,479,302]	0	hSpCas9	negative selection	1745029
468763	468786	8	-	26627737	HeLa	viability after 18 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.0153401760557095	[359]	[188,181,394]	7	hSpCas9	negative selection	1745053
458431	458454	8	-	26627737	HCT116	viability after 6 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.09328222404408715	[2036]	[349,336]	0	hSpCas9	negative selection	1827336
458449	458472	8	+	26627737	HCT116	viability after 6 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.337360060571462	[407]	[120,58]	2	hSpCas9	negative selection	1827337
463072	463095	8	+	26627737	HCT116	viability after 6 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-1.2158275508389471	[1295]	[195,27]	-6	hSpCas9	negative selection	1827344
468763	468786	8	-	26627737	HCT116	viability after 6 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	3.549980902290721	[264]	[699,370]	9	hSpCas9	negative selection	1827368
458431	458454	8	-	26627737	HCT116	viability after 8 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.28767247589744294	[596]	[408,410,384]	3	hSpCas9	negative selection	1909651
458449	458472	8	+	26627737	HCT116	viability after 8 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.025678538695348224	[361]	[193,294,99]	0	hSpCas9	negative selection	1909652
463072	463095	8	+	26627737	HCT116	viability after 8 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.40550270148677126	[584]	[482,461,337]	4	hSpCas9	negative selection	1909659
468763	468786	8	-	26627737	HCT116	viability after 8 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.7805508413528515	[207]	[220,166,202]	7	hSpCas9	negative selection	1909683
458431	458454	8	-	26627737	HCT116	viability after 9 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.13632338454958925	[2036]	[724,312]	-1	hSpCas9	negative selection	1991966
458449	458472	8	+	26627737	HCT116	viability after 9 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.32079165239370827	[407]	[39,211]	2	hSpCas9	negative selection	1991967
463072	463095	8	+	26627737	HCT116	viability after 9 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.7859211798993064	[1295]	[575,612]	5	hSpCas9	negative selection	1991974
468763	468786	8	-	26627737	HCT116	viability after 9 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.5679006140594054	[264]	[311,128]	8	hSpCas9	negative selection	1991998
458431	458454	8	-	26627737	HCT116	viability after 12 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.3184387452852071	[596]	[381,370,420]	3	hSpCas9	negative selection	2074281
458449	458472	8	+	26627737	HCT116	viability after 12 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.029082539137086832	[361]	[123,193,246]	0	hSpCas9	negative selection	2074282
463072	463095	8	+	26627737	HCT116	viability after 12 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.1129708393686929	[584]	[231,307,317]	-1	hSpCas9	negative selection	2074289
468763	468786	8	-	26627737	HCT116	viability after 12 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.1212227969248223	[207]	[245,211,253]	8	hSpCas9	negative selection	2074313
458431	458454	8	-	26627737	HCT116	viability after 15 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.3448331929406361	[596]	[479,420,410]	3	hSpCas9	negative selection	2156596
458449	458472	8	+	26627737	HCT116	viability after 15 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.5851938261566686	[361]	[142,195,77]	-6	hSpCas9	negative selection	2156597
463072	463095	8	+	26627737	HCT116	viability after 15 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.33396836911730887	[584]	[563,422,301]	3	hSpCas9	negative selection	2156604
468763	468786	8	-	26627737	HCT116	viability after 15 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.7756197336076478	[207]	[267,130,221]	6	hSpCas9	negative selection	2156628
458431	458454	8	-	26627737	HCT116	viability after 18 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.32729804444795496	[596]	[368,370,344]	3	hSpCas9	negative selection	2238911
458449	458472	8	+	26627737	HCT116	viability after 18 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.0787425067118177	[361]	[128,181,185]	0	hSpCas9	negative selection	2238912
463072	463095	8	+	26627737	HCT116	viability after 18 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.003395307459476027	[584]	[222,277,352]	0	hSpCas9	negative selection	2238919
468763	468786	8	-	26627737	HCT116	viability after 18 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	1.567183739205403	[207]	[301,115,496]	9	hSpCas9	negative selection	2238943
450011	450034	8	+	24336569	HL60	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	4.2353022891426875	[6]	[278]	9	hSpCas9	negative selection	2266099
450016	450039	8	+	24336569	HL60	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.40078517636130306	[621]	[996]	-4	hSpCas9	negative selection	2266100
451351	451374	8	+	24336569	HL60	viability	AGTAGGGAAGTCTGTATTAGTGG	FBXO25	ENSG00000147364	0.8562516211167609	[354]	[1359]	7	hSpCas9	negative selection	2266101
451368	451391	8	+	24336569	HL60	viability	TAGTGGGAAACATCAATATTTGG	FBXO25	ENSG00000147364	0.603163864929384	[246]	[793]	5	hSpCas9	negative selection	2266102
450011	450034	8	+	24336569	KBM7	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.08811575925557746	[138]	[402]	0	hSpCas9	negative selection	2333276
450016	450039	8	+	24336569	KBM7	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.393195191587829	[444]	[1593]	3	hSpCas9	negative selection	2333277
451351	451374	8	+	24336569	KBM7	viability	AGTAGGGAAGTCTGTATTAGTGG	FBXO25	ENSG00000147364	-0.004314780881037816	[309]	[842]	0	hSpCas9	negative selection	2333278
451368	451391	8	+	24336569	KBM7	viability	TAGTGGGAAACATCAATATTTGG	FBXO25	ENSG00000147364	-0.004115261348676957	[445]	[1212]	0	hSpCas9	negative selection	2333279
406667	406690	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACGGTGAAGACCTGAGATTTAGG	FBXO25	ENSG00000147364	-1.005882731248147	[99,751]	[32,61]	-6	dCas9-VP64	positive selection	2474186
406623	406646	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCCGTGAAGACCCGGACCGG	FBXO25	ENSG00000147364	0.9992034671070307	[134,158]	[85,40]	4	dCas9-VP64	positive selection	2474187
406696	406719	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGAGATCCCTGCGATCGCTGG	FBXO25	ENSG00000147364	-0.3176438019286638	[214,186]	[33,35]	-1	dCas9-VP64	positive selection	2474189
406667	406690	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACGGTGAAGACCTGAGATTTAGG	FBXO25	ENSG00000147364	-0.1893497952463774	[233,114]	[67,32]	-2	dCas9-VP64	positive selection	2569441
406623	406646	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCCGTGAAGACCCGGACCGG	FBXO25	ENSG00000147364	-0.3217268846818367	[260,44]	[72,8]	-3	dCas9-VP64	positive selection	2569442
406696	406719	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGAGATCCCTGCGATCGCTGG	FBXO25	ENSG00000147364	0.021887455331657812	[165,216]	[68,57]	0	dCas9-VP64	positive selection	2569444
450017	450040	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.08826229659669751	[3,3]	[4,1]	1	hSpCas9	positive selection	2988176
450017	450040	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.18714255186323558	[3,3]	[2,1]	-3	hSpCas9	positive selection	3056034
431385	431408		+	24336571	A375	resistance to PLX after 7 days	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.13607681626930512	[4,4]	[3,4]	-4	hSpCas9	positive selection	3114251
450013	450036		-	24336571	A375	resistance to PLX after 7 days	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.11933412257012022	[22,22]	[18,22]	-4	hSpCas9	positive selection	3114252
450011	450034		+	24336571	A375	resistance to PLX after 7 days	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.06497039572357033	[42,45]	[40,42]	-2	hSpCas9	positive selection	3114253
431385	431408		+	24336571	A375	resistance to PLX after 14 days	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.3996364059032821	[7,4]	[1,1]	-5	hSpCas9	positive selection	3172044
450013	450036		-	24336571	A375	resistance to PLX after 14 days	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.08077676342263407	[22,22]	[10,8]	-1	hSpCas9	positive selection	3172045
450011	450034		+	24336571	A375	resistance to PLX after 14 days	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.11439215702718664	[39,39]	[16,15]	-1	hSpCas9	positive selection	3172046
431385	431408		+	24336571	A375	viability after 7 days	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.7396800068195492	[8]	[4,4]	-8	hSpCas9	negative selection	3229837
450013	450036		-	24336571	A375	viability after 7 days	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.1675849608001343	[26]	[22,22]	-2	hSpCas9	negative selection	3229838
450011	450034		+	24336571	A375	viability after 7 days	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.6253183865360281	[29]	[42,45]	8	hSpCas9	negative selection	3229839
431385	431408		+	24336571	A375	viability after 14 days	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.3908778522663756	[8]	[7,4]	-5	hSpCas9	negative selection	3287630
450013	450036		-	24336571	A375	viability after 14 days	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.17157098629980938	[26]	[22,22]	-2	hSpCas9	negative selection	3287631
450011	450034		+	24336571	A375	viability after 14 days	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.47951424788625885	[29]	[39,39]	6	hSpCas9	negative selection	3287632
450013	450036	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	1.224839253438417	[58,71]	[0,0]	5	hSpCas9	positive selection	3349695
463072	463095	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.8925478122653564	[68,95]	[0,0]	4	hSpCas9	positive selection	3349696
463085	463108	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-1.0835129550297435	[281,366]	[0,0]	-7	hSpCas9	positive selection	3349697
450011	450034	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.4291743157373832	[205,205]	[0,0]	-3	hSpCas9	positive selection	3368907
431385	431408	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3368908
432914	432937	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	2.3795819614968328	[734,734]	[24,24]	8	hSpCas9	positive selection	3368909
450016	450039	8	+	26780180	HT29	viability (Avana library 4 designs)	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	1.69049221143316	[]	[]	6	hSpCas9	negative selection	3425075
450016	450039	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	2.54180754217732	[]	[]	4	hSpCas9	negative selection	3507028
435667	435690	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCAATTCAAGATATCCGAAGG	FBXO25	ENSG00000147364	-10.2974346271043	[]	[]	-7	hSpCas9	negative selection	3507029
435631	435654	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGGGAGAAGCCTTTAATCGG	FBXO25	ENSG00000147364	5.18589761836801	[]	[]	8	hSpCas9	negative selection	3507030
450016	450039	8	+	26780180	A375	viability (Avana lentiGuide)	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-4.85789640671545	[]	[]	-8	hSpCas9	negative selection	3615687
435667	435690	8	+	26780180	A375	viability (Avana lentiGuide)	GTGCAATTCAAGATATCCGAAGG	FBXO25	ENSG00000147364	15.5231000878765	[]	[]	8	hSpCas9	negative selection	3615688
435631	435654	8	+	26780180	A375	viability (Avana lentiGuide)	CCTTGGGAGAAGCCTTTAATCGG	FBXO25	ENSG00000147364	0.0452982421166412	[]	[]	0	hSpCas9	negative selection	3615689
450016	450039	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.06771024611744828	[5]	[5,4]	1	hSpCas9	positive selection	3724346
435667	435690	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCAATTCAAGATATCCGAAGG	FBXO25	ENSG00000147364	-0.7841912903514783	[5]	[2,2]	-8	hSpCas9	positive selection	3724347
435631	435654	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGGGAGAAGCCTTTAATCGG	FBXO25	ENSG00000147364	0.26803229558414	[5]	[6,7]	7	hSpCas9	positive selection	3724348
450016	450039	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.47813775642578354	[5]	[3,1]	-6	hSpCas9	positive selection	3832953
435667	435690	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCAATTCAAGATATCCGAAGG	FBXO25	ENSG00000147364	-0.7900760797745157	[5]	[3,1]	-7	hSpCas9	positive selection	3832954
435631	435654	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGGGAGAAGCCTTTAATCGG	FBXO25	ENSG00000147364	0.17554604489043213	[6]	[6,6]	4	hSpCas9	positive selection	3832955
431385	431408	8	+	26780180	A375	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.723204098131706	[]	[]	2	hSpCas9	negative selection	3940218
450013	450036	8	-	26780180	A375	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	1.39401259330976	[]	[]	7	hSpCas9	negative selection	3940219
432914	432937	8	-	26780180	A375	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.191070482526277	[]	[]	0	hSpCas9	negative selection	3940220
463072	463095	8	+	26780180	A375	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	1.30328609995405	[]	[]	7	hSpCas9	negative selection	3940221
450011	450034	8	+	26780180	A375	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.622861616950824	[]	[]	2	hSpCas9	negative selection	3940222
463085	463108	8	-	26780180	A375	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.208263682756146	[]	[]	0	hSpCas9	negative selection	3940223
431385	431408	8	+	26780180	HT29	viability (GeCKOv2 library)	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	1.77232973600752	[]	[]	8	hSpCas9	negative selection	4048184
450013	450036	8	-	26780180	HT29	viability (GeCKOv2 library)	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	2.36609257612212	[]	[]	9	hSpCas9	negative selection	4048185
432914	432937	8	-	26780180	HT29	viability (GeCKOv2 library)	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	-0.632532934528298	[]	[]	-9	hSpCas9	negative selection	4048186
463072	463095	8	+	26780180	HT29	viability (GeCKOv2 library)	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.566946798961131	[]	[]	2	hSpCas9	negative selection	4048187
450011	450034	8	+	26780180	HT29	viability (GeCKOv2 library)	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.959855596037177	[]	[]	4	hSpCas9	negative selection	4048188
463085	463108	8	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.833547116590498	[]	[]	3	hSpCas9	negative selection	4048189
431385	431408	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.5534059769732816	[2]	[1,0]	-9	hSpCas9	positive selection	4137255
450013	450036	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.009374856936798792	[4]	[2,3]	0	hSpCas9	positive selection	4137256
450011	450034	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.5234180953184019	[5]	[6,4]	9	hSpCas9	positive selection	4137257
431385	431408	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.6423382932355419	[2]	[2,4,1,0]	4	hSpCas9	positive selection	4201277
450013	450036	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.037226567589826356	[4]	[1,0,4,0]	0	hSpCas9	positive selection	4201278
450011	450034	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.8953221771221971	[4]	[3,4,2,3]	6	hSpCas9	positive selection	4201279
450013	450036	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-1.206247475929057	[1]	[0,0]	-9	hSpCas9	positive selection	4270743
463072	463095	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.033706297770585314	[2]	[2,1]	0	hSpCas9	positive selection	4270744
463085	463108	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.0676445432743073	[4]	[3,2]	1	hSpCas9	positive selection	4270745
450011	450034	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.05300998550118662	[3]	[3,1]	-1	hSpCas9	positive selection	4335007
431385	431408	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.45033988534083813	[1]	[0,0]	-7	hSpCas9	positive selection	4335008
432914	432937	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6253861030485981	[4]	[5,4]	9	hSpCas9	positive selection	4335009
450017	450039	8	+	27760321	OCIAML3	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.23039647446233624	[378,427]	[298,234]	-2	hSpCas9	negative selection	4400622
450062	450084	8	+	27760321	OCIAML3	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.6264363932698451	[24,23]	[13,49]	7	hSpCas9	negative selection	4400623
451399	451421	8	+	27760321	OCIAML3	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.42308632206428726	[468,300]	[209,235]	-4	hSpCas9	negative selection	4400624
458428	458450	8	+	27760321	OCIAML3	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.40764126111127386	[479,358]	[381,495]	5	hSpCas9	negative selection	4400625
450017	450039	8	+	27760321	OCIAML2	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.5284641450802047	[378,427]	[453,501]	7	hSpCas9	negative selection	4484085
450062	450084	8	+	27760321	OCIAML2	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.5133949713526476	[24,23]	[20,37]	7	hSpCas9	negative selection	4484086
451399	451421	8	+	27760321	OCIAML2	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.22389140870038077	[468,300]	[273,247]	-3	hSpCas9	negative selection	4484087
458428	458450	8	+	27760321	OCIAML2	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.14133644082848873	[479,358]	[295,469]	1	hSpCas9	negative selection	4484088
450017	450039	8	+	27760321	MV411	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-1.9154792067635913	[378,427]	[31,129]	-8	hSpCas9	negative selection	4567548
450062	450084	8	+	27760321	MV411	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	-4.0173503768081185	[24,23]	[0,0]	-9	hSpCas9	negative selection	4567549
451399	451421	8	+	27760321	MV411	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-1.2786566414731961	[468,300]	[87,125]	-7	hSpCas9	negative selection	4567550
458428	458450	8	+	27760321	MV411	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.5835124809742069	[479,358]	[131,259]	-4	hSpCas9	negative selection	4567551
450017	450039	8	+	27760321	HL60	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.10303067558453549	[378,427]	[271,446]	1	hSpCas9	negative selection	4651011
450062	450084	8	+	27760321	HL60	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	1.4332396508311014	[24,23]	[41,66]	9	hSpCas9	negative selection	4651012
451399	451421	8	+	27760321	HL60	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.1831137479210389	[468,300]	[254,291]	-2	hSpCas9	negative selection	4651013
458428	458450	8	+	27760321	HL60	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.17809747774629825	[479,358]	[309,289]	-2	hSpCas9	negative selection	4651014
450017	450039	8	+	27760321	HT1080	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	1.7834336851132087	[427,333]	[184,891]	8	hSpCas9	negative selection	4734474
450062	450084	8	+	27760321	HT1080	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	-3.0997209182049863	[23,18]	[0,0]	-7	hSpCas9	negative selection	4734475
451399	451421	8	+	27760321	HT1080	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	0.02396644887953364	[300,234]	[56,164]	0	hSpCas9	negative selection	4734476
458428	458450	8	+	27760321	HT1080	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	1.1948923629590236	[358,279]	[414,155]	6	hSpCas9	negative selection	4734477
450017	450039	8	+	27760321	HT29	viability after 7 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.51366620693494	[427,333]	[495,222,331]	-6	hSpCas9	negative selection	4817937
450062	450084	8	+	27760321	HT29	viability after 7 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.1505102320990468	[23,18]	[52,34,7]	2	hSpCas9	negative selection	4817938
451399	451421	8	+	27760321	HT29	viability after 7 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.171185799795731	[300,234]	[500,92,349]	-3	hSpCas9	negative selection	4817939
458428	458450	8	+	27760321	HT29	viability after 7 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.40373592036771877	[358,279]	[516,415,687]	6	hSpCas9	negative selection	4817940
450017	450039	8	+	27760321	HT29	viability after 25 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.42141589040174554	[427,333]	[693,416,635]	4	hSpCas9	negative selection	4901400
450062	450084	8	+	27760321	HT29	viability after 25 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.45913568786954073	[23,18]	[30,6,66]	5	hSpCas9	negative selection	4901401
451399	451421	8	+	27760321	HT29	viability after 25 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.15009300146197424	[300,234]	[322,153,355]	-1	hSpCas9	negative selection	4901402
458428	458450	8	+	27760321	HT29	viability after 25 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.7248486118354873	[358,279]	[616,566,626]	8	hSpCas9	negative selection	4901403
450017	450039	8	+	27760321	HT29	viability after 22 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.005143586666833733	[427,333]	[461,370,492]	0	hSpCas9	negative selection	4984863
450062	450084	8	+	27760321	HT29	viability after 22 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.8474887190274862	[23,18]	[52,42,37]	8	hSpCas9	negative selection	4984864
451399	451421	8	+	27760321	HT29	viability after 22 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.8916990729852657	[300,234]	[110,169,221]	-6	hSpCas9	negative selection	4984865
458428	458450	8	+	27760321	HT29	viability after 22 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.3610700452328026	[358,279]	[355,627,441]	4	hSpCas9	negative selection	4984866
450017	450039	8	+	27760321	HT29	viability after 19 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.021987690420004466	[427,333]	[698,296,360]	0	hSpCas9	negative selection	5068326
450062	450084	8	+	27760321	HT29	viability after 19 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.6053027632140231	[23,18]	[79,5,30]	6	hSpCas9	negative selection	5068327
451399	451421	8	+	27760321	HT29	viability after 19 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	0.04899618312312676	[300,234]	[304,546,105]	0	hSpCas9	negative selection	5068328
458428	458450	8	+	27760321	HT29	viability after 19 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.49105997199093226	[358,279]	[582,301,656]	5	hSpCas9	negative selection	5068329
450017	450039	8	+	27760321	HT29	viability after 16 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.0165837425853365	[427,333]	[548,416,338]	0	hSpCas9	negative selection	5151789
450062	450084	8	+	27760321	HT29	viability after 16 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.8834902679307581	[23,18]	[45,20,66]	9	hSpCas9	negative selection	5151790
451399	451421	8	+	27760321	HT29	viability after 16 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	0.041164565853091084	[300,234]	[212,365,335]	0	hSpCas9	negative selection	5151791
458428	458450	8	+	27760321	HT29	viability after 16 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.4801400227147059	[358,279]	[584,492,425]	5	hSpCas9	negative selection	5151792
450017	450039	8	+	27760321	HT29	viability after 13 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.13277074339324818	[427,333]	[697,317,439]	1	hSpCas9	negative selection	5235252
450062	450084	8	+	27760321	HT29	viability after 13 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	-0.2983069971390151	[23,18]	[10,47,2]	-4	hSpCas9	negative selection	5235253
451399	451421	8	+	27760321	HT29	viability after 13 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.6366293796332677	[300,234]	[162,253,183]	-6	hSpCas9	negative selection	5235254
458428	458450	8	+	27760321	HT29	viability after 13 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.0275746762658092	[358,279]	[500,236,393]	0	hSpCas9	negative selection	5235255
450017	450039	8	+	27760321	HT29	viability after 10 days	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.21218809146815115	[427,333]	[544,751,365]	3	hSpCas9	negative selection	5318715
450062	450084	8	+	27760321	HT29	viability after 10 days	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	0.5588673074413331	[23,18]	[81,25,10]	7	hSpCas9	negative selection	5318716
451399	451421	8	+	27760321	HT29	viability after 10 days	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-0.3682771088882981	[300,234]	[248,390,143]	-5	hSpCas9	negative selection	5318717
458428	458450	8	+	27760321	HT29	viability after 10 days	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.18060249868836942	[358,279]	[473,337,538]	2	hSpCas9	negative selection	5318718
450017	450039	8	+	27760321	MOLM13	viability	TTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	1.1158323455561043	[378,427]	[403,576]	7	hSpCas9	negative selection	5402178
450062	450084	8	+	27760321	MOLM13	viability	TTGGATAAAATCGTTCAAAAGG	FBXO25	ENSG00000147364	-3.791293563980523	[24,23]	[0,0]	-9	hSpCas9	negative selection	5402179
451399	451421	8	+	27760321	MOLM13	viability	ATTAGAAACTATTCTCGCCTGG	FBXO25	ENSG00000147364	-3.2449852918025823	[468,300]	[34,11]	-9	hSpCas9	negative selection	5402180
458428	458450	8	+	27760321	MOLM13	viability	ATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.8537557452982381	[479,358]	[597,275]	6	hSpCas9	negative selection	5402181
406913	406936	8	+	27661255	K562	viability	GGGGCTTCCCTGAGGCGCGCCGG	FBXO25	ENSG00000147364	0.10779172291488615	[528,571]	[463,480]	4	dCas9-KRAB	negative selection	5479747
407251	407274	8	+	27661255	K562	viability	GGCCTGTGGGAGGGTCAGGTGGG	FBXO25	ENSG00000147364	0.12618601983464717	[134,263]	[152,187]	4	dCas9-KRAB	negative selection	5479748
407369	407392	8	+	27661255	K562	viability	GTCCGCGGGCGCGTCAGGTAGGG	FBXO25	ENSG00000147364	0.14743079590566138	[599,879]	[673,629]	5	dCas9-KRAB	negative selection	5479749
407446	407469	8	+	27661255	K562	viability	GGGTTCATTCAGGGAGCTGCGGG	FBXO25	ENSG00000147364	0.17018263976569636	[544,774]	[636,548]	6	dCas9-KRAB	negative selection	5479750
450013	450036	8	-	27260156	BXPC3	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3122427127220949	[196]	[226,277,254,263]	6	hSpCas9	negative selection	5543203
463072	463095	8	+	27260156	BXPC3	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.05395730176074964	[299]	[359,341,285,303]	1	hSpCas9	negative selection	5543204
463085	463108	8	-	27260156	BXPC3	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.0596663153582071	[1052]	[977,1045,973,1251]	-1	hSpCas9	negative selection	5543205
450011	450034	8	+	27260156	BXPC3	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.12321919146062893	[551]	[488,595,706,751]	2	hSpCas9	negative selection	5607467
431385	431408	8	+	27260156	BXPC3	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.1483114004000421	[158]	[225,74,118,177]	-3	hSpCas9	negative selection	5607468
432914	432937	8	-	27260156	BXPC3	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5784690398788193	[1022]	[1416,1525,1662,1824]	9	hSpCas9	negative selection	5607469
450013	450036	8	-	27260156	A673	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.08888325996482638	[196]	[289,173,264,284]	2	hSpCas9	negative selection	5664454
463072	463095	8	+	27260156	A673	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.12741755857299075	[299]	[551,347,335,354]	3	hSpCas9	negative selection	5664455
463085	463108	8	-	27260156	A673	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.0041105189147983	[1052]	[1480,1083,1393,1130]	0	hSpCas9	negative selection	5664456
450011	450034	8	+	27260156	A673	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.13336730115701784	[551]	[697,661,744,803]	3	hSpCas9	negative selection	5728718
431385	431408	8	+	27260156	A673	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.04174114588763045	[158]	[268,176,119,185]	-1	hSpCas9	negative selection	5728719
432914	432937	8	-	27260156	A673	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.660575464973685	[1022]	[2001,1768,1770,2250]	9	hSpCas9	negative selection	5728720
450013	450036	8	-	27260156	A375	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.5957225676001012	[196]	[283,277,382,424]	8	hSpCas9	negative selection	5785705
463072	463095	8	+	27260156	A375	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.191947671690204	[299]	[373,307,288,260]	-3	hSpCas9	negative selection	5785706
463085	463108	8	-	27260156	A375	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.18829231393145873	[1052]	[1747,1550,1178,1172]	2	hSpCas9	negative selection	5785707
450011	450034	8	+	27260156	A375	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.13832826615179844	[551]	[476,808,807,748]	2	hSpCas9	negative selection	5849969
431385	431408	8	+	27260156	A375	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.03545873649914366	[158]	[241,254,156,123]	0	hSpCas9	negative selection	5849970
432914	432937	8	-	27260156	A375	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.9654361391334847	[1022]	[2573,2445,2376,1985]	9	hSpCas9	negative selection	5849971
450013	450036	8	-	27260156	COLO741	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.23810201442059076	[196]	[368,258,269]	5	hSpCas9	negative selection	5906956
463072	463095	8	+	27260156	COLO741	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.004422891492784409	[299]	[404,367,374]	0	hSpCas9	negative selection	5906957
463085	463108	8	-	27260156	COLO741	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.2008528757516539	[1052]	[1809,1446,1410]	4	hSpCas9	negative selection	5906958
450011	450034	8	+	27260156	COLO741	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.22738032574904166	[551]	[783,906,783]	5	hSpCas9	negative selection	5971220
431385	431408	8	+	27260156	COLO741	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.3142226135605244	[158]	[208,112,170]	-6	hSpCas9	negative selection	5971221
432914	432937	8	-	27260156	COLO741	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5673614473345554	[1022]	[2049,1889,1879]	9	hSpCas9	negative selection	5971222
450013	450036	8	-	27260156	CAL120	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.5431272147080899	[196]	[525,276,294]	7	hSpCas9	negative selection	6028207
463072	463095	8	+	27260156	CAL120	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.05307394947826638	[299]	[518,207,375]	-1	hSpCas9	negative selection	6028208
463085	463108	8	-	27260156	CAL120	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.3039847110746594	[1052]	[1864,1765,1264]	4	hSpCas9	negative selection	6028209
450011	450034	8	+	27260156	CAL120	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	1.0130898349854442	[551]	[3029,676,710]	9	hSpCas9	negative selection	6092471
431385	431408	8	+	27260156	CAL120	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.020733598212079984	[158]	[78,261,225]	0	hSpCas9	negative selection	6092472
432914	432937	8	-	27260156	CAL120	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5955370496588743	[1022]	[2823,1640,1448]	8	hSpCas9	negative selection	6092473
450013	450036	8	-	27260156	CADOES1	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3772526396759124	[196]	[337,201,239,168]	6	hSpCas9	negative selection	6149458
463072	463095	8	+	27260156	CADOES1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.10908802463935752	[299]	[213,290,244,285]	-2	hSpCas9	negative selection	6149459
463085	463108	8	-	27260156	CADOES1	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.028900116701287892	[1052]	[995,962,834,1048]	0	hSpCas9	negative selection	6149460
450011	450034	8	+	27260156	CADOES1	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.20471475429659086	[551]	[583,390,651,744]	3	hSpCas9	negative selection	6213722
431385	431408	8	+	27260156	CADOES1	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.12667117551400087	[158]	[150,198,104,84]	-2	hSpCas9	negative selection	6213723
432914	432937	8	-	27260156	CADOES1	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	1.0077399738690622	[1022]	[1513,2254,2003,1879]	9	hSpCas9	negative selection	6213724
450013	450036	8	-	27260156	EWS502	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.056728419856086676	[196]	[254,157,159,296]	1	hSpCas9	negative selection	6270709
463072	463095	8	+	27260156	EWS502	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.10373465447626018	[299]	[236,247,288,425]	-2	hSpCas9	negative selection	6270710
463085	463108	8	-	27260156	EWS502	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.026166042723948735	[1052]	[955,1227,1044,1340]	0	hSpCas9	negative selection	6270711
450011	450034	8	+	27260156	EWS502	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.30264082533056247	[551]	[462,720,691,1060]	5	hSpCas9	negative selection	6334973
431385	431408	8	+	27260156	EWS502	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.5722906391748555	[158]	[72,143,132,105]	-7	hSpCas9	negative selection	6334974
432914	432937	8	-	27260156	EWS502	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6515612462969542	[1022]	[1716,1442,1742,1923]	9	hSpCas9	negative selection	6334975
450013	450036	8	-	27260156	EW8	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3500478763112701	[196]	[122,284,112,298]	6	hSpCas9	negative selection	6391960
463072	463095	8	+	27260156	EW8	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.2107676927811385	[299]	[325,226,192,397]	4	hSpCas9	negative selection	6391961
463085	463108	8	-	27260156	EW8	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.1493408935675664	[1052]	[1090,875,890,949]	2	hSpCas9	negative selection	6391962
450011	450034	8	+	27260156	EW8	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.21966788638008639	[551]	[482,601,595,384]	4	hSpCas9	negative selection	6456224
431385	431408	8	+	27260156	EW8	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.42640291626480287	[158]	[117,108,58,105]	-7	hSpCas9	negative selection	6456225
432914	432937	8	-	27260156	EW8	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.7771643518893712	[1022]	[1699,1329,1149,1574]	9	hSpCas9	negative selection	6456226
450013	450036	8	-	27260156	CORL105	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3169985329375955	[196]	[244,212,495,227]	6	hSpCas9	negative selection	6513211
463072	463095	8	+	27260156	CORL105	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.5607171692808585	[299]	[569,429,609,479]	8	hSpCas9	negative selection	6513212
463085	463108	8	-	27260156	CORL105	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.10210157538961151	[1052]	[1210,1208,1744,1191]	2	hSpCas9	negative selection	6513213
450011	450034	8	+	27260156	CORL105	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.45370842005818335	[551]	[813,1007,783,912]	8	hSpCas9	negative selection	6577475
431385	431408	8	+	27260156	CORL105	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.769445435989081	[158]	[111,102,171,59]	-8	hSpCas9	negative selection	6577476
432914	432937	8	-	27260156	CORL105	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5968767502239547	[1022]	[1944,1603,2117,1634]	9	hSpCas9	negative selection	6577477
450013	450036	8	-	27260156	HS294T	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	1.1452039428761869	[196]	[351,95,95,102]	9	hSpCas9	negative selection	6634462
463072	463095	8	+	27260156	HS294T	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.44654418546401575	[299]	[148,137,114,245]	6	hSpCas9	negative selection	6634463
463085	463108	8	-	27260156	HS294T	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.2718216161022484	[1052]	[476,507,390,608]	3	hSpCas9	negative selection	6634464
450011	450034	8	+	27260156	HS294T	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.6039705379900279	[551]	[136,144,150,125]	-7	hSpCas9	negative selection	6698726
431385	431408	8	+	27260156	HS294T	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.44987730757050604	[158]	[59,130,22,129]	6	hSpCas9	negative selection	6698727
432914	432937	8	-	27260156	HS294T	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.3325486409497749	[1022]	[393,525,540,546]	4	hSpCas9	negative selection	6698728
450013	450036	8	-	27260156	HCC44	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3272104120786816	[196]	[274,266,195,361]	5	hSpCas9	negative selection	6755713
463072	463095	8	+	27260156	HCC44	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.03574556467461387	[299]	[131,311,469,412]	0	hSpCas9	negative selection	6755714
463085	463108	8	-	27260156	HCC44	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.10854770160172489	[1052]	[1182,1102,1656,1263]	1	hSpCas9	negative selection	6755715
450011	450034	8	+	27260156	HCC44	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.3506445792044741	[551]	[929,592,1043,697]	6	hSpCas9	negative selection	6819977
431385	431408	8	+	27260156	HCC44	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.5892513367036711	[158]	[118,139,159,63]	-7	hSpCas9	negative selection	6819978
432914	432937	8	-	27260156	HCC44	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.7572617733718792	[1022]	[2219,1344,2830,1681]	9	hSpCas9	negative selection	6819979
450013	450036	8	-	27260156	G402	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.26283447327096165	[196]	[373,122,384,273]	3	hSpCas9	negative selection	6876964
463072	463095	8	+	27260156	G402	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.26486869906935734	[299]	[486,783,339,185]	3	hSpCas9	negative selection	6876965
463085	463108	8	-	27260156	G402	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.3121710493743657	[1052]	[1773,2072,1633,977]	4	hSpCas9	negative selection	6876966
450011	450034	8	+	27260156	G402	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.3513013159966798	[551]	[1360,453,477,1173]	4	hSpCas9	negative selection	6941228
431385	431408	8	+	27260156	G402	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.7823219800760617	[158]	[127,155,111,61]	-7	hSpCas9	negative selection	6941229
432914	432937	8	-	27260156	G402	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	1.1996798615710738	[1022]	[3786,2223,2826,2721]	9	hSpCas9	negative selection	6941230
450013	450036	8	-	27260156	L33	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.18123042548658708	[196]	[189,114,111,244]	4	hSpCas9	negative selection	6998215
463072	463095	8	+	27260156	L33	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.007448141620330473	[299]	[403,76,145,365]	0	hSpCas9	negative selection	6998216
463085	463108	8	-	27260156	L33	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.2245034330321254	[1052]	[1116,522,844,1186]	5	hSpCas9	negative selection	6998217
450011	450034	8	+	27260156	L33	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.09614274643814688	[551]	[461,231,311,541]	-2	hSpCas9	negative selection	7062479
431385	431408	8	+	27260156	L33	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.38602313112716047	[158]	[97,63,42,163]	-7	hSpCas9	negative selection	7062480
432914	432937	8	-	27260156	L33	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.24685728044899768	[1022]	[1249,378,949,1169]	5	hSpCas9	negative selection	7062481
450013	450036	8	-	27260156	K562	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.15142364203051661	[196]	[122,61,154,267]	-2	hSpCas9	negative selection	7119466
463072	463095	8	+	27260156	K562	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.16445280782016047	[299]	[252,135,260,288]	-2	hSpCas9	negative selection	7119467
463085	463108	8	-	27260156	K562	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.09746239197344164	[1052]	[848,1136,917,626]	-1	hSpCas9	negative selection	7119468
450011	450034	8	+	27260156	K562	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.13042296384755375	[551]	[788,568,506,324]	1	hSpCas9	negative selection	7183730
431385	431408	8	+	27260156	K562	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.43093993971667643	[158]	[122,87,198,18]	-5	hSpCas9	negative selection	7183731
432914	432937	8	-	27260156	K562	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.9075909601770729	[1022]	[2030,1590,1285,1894]	9	hSpCas9	negative selection	7183732
450013	450036	8	-	27260156	HT29	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.26809205343348064	[196]	[292,342,236,283]	5	hSpCas9	negative selection	7240717
463072	463095	8	+	27260156	HT29	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.03824077824920202	[299]	[431,290,399,369]	0	hSpCas9	negative selection	7240718
463085	463108	8	-	27260156	HT29	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.1013942076028378	[1052]	[1526,1289,1318,1353]	2	hSpCas9	negative selection	7240719
450011	450034	8	+	27260156	HT29	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.3123155234240068	[551]	[926,903,917,617]	6	hSpCas9	negative selection	7304981
431385	431408	8	+	27260156	HT29	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.6308086466684508	[158]	[146,107,121,121]	-8	hSpCas9	negative selection	7304982
432914	432937	8	-	27260156	HT29	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.7858670862505048	[1022]	[2597,2021,2035,1952]	9	hSpCas9	negative selection	7304983
450013	450036	8	-	27260156	MHHES1	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.25699057363056776	[196]	[247,286,322,209]	5	hSpCas9	negative selection	7361968
463072	463095	8	+	27260156	MHHES1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.002186489045403306	[299]	[476,156,309,387]	0	hSpCas9	negative selection	7361969
463085	463108	8	-	27260156	MHHES1	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.4000472595728468	[1052]	[1623,1556,2140,1036]	7	hSpCas9	negative selection	7361970
450011	450034	8	+	27260156	MHHES1	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.2537112057953404	[551]	[731,1030,681,570]	4	hSpCas9	negative selection	7426232
431385	431408	8	+	27260156	MHHES1	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.4082485131771383	[158]	[137,223,106,87]	-6	hSpCas9	negative selection	7426233
432914	432937	8	-	27260156	MHHES1	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.7201850468334383	[1022]	[2254,2128,1916,1425]	9	hSpCas9	negative selection	7426234
450013	450036	8	-	27260156	MEWO	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.08569912126366908	[196]	[249,127,157]	-2	hSpCas9	negative selection	7483219
463072	463095	8	+	27260156	MEWO	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.04405434309420475	[299]	[340,299,236]	1	hSpCas9	negative selection	7483220
463085	463108	8	-	27260156	MEWO	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.12233800318527988	[1052]	[980,836,911]	-3	hSpCas9	negative selection	7483221
450011	450034	8	+	27260156	MEWO	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.2509225347093784	[551]	[632,623,589]	5	hSpCas9	negative selection	7547483
431385	431408	8	+	27260156	MEWO	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.33057052218043204	[158]	[118,115,119]	-6	hSpCas9	negative selection	7547484
432914	432937	8	-	27260156	MEWO	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5056344081653161	[1022]	[1437,1250,1402]	8	hSpCas9	negative selection	7547485
450013	450036	8	-	27260156	LNCAPCLONEFGC	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.04779963828616096	[196]	[198,136,166,234]	0	hSpCas9	negative selection	7604470
463072	463095	8	+	27260156	LNCAPCLONEFGC	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.8530296920676855	[299]	[146,89,178,193]	-8	hSpCas9	negative selection	7604471
463085	463108	8	-	27260156	LNCAPCLONEFGC	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.09378799767553492	[1052]	[1022,919,1223,940]	1	hSpCas9	negative selection	7604472
450011	450034	8	+	27260156	LNCAPCLONEFGC	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.10590370407418329	[551]	[404,466,590,414]	-2	hSpCas9	negative selection	7668734
431385	431408	8	+	27260156	LNCAPCLONEFGC	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.38357490419331985	[158]	[192,215,170,166]	6	hSpCas9	negative selection	7668735
432914	432937	8	-	27260156	LNCAPCLONEFGC	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.8058946488044454	[1022]	[1317,1479,1954,1790]	9	hSpCas9	negative selection	7668736
450013	450036	8	-	27260156	PANC0327	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.050173594606209404	[196]	[227,269,107,110]	0	hSpCas9	negative selection	7725721
463072	463095	8	+	27260156	PANC0327	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.06199294584036941	[299]	[157,341,300,200]	-1	hSpCas9	negative selection	7725722
463085	463108	8	-	27260156	PANC0327	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.023539824785785424	[1052]	[1066,890,912,948]	0	hSpCas9	negative selection	7725723
450011	450034	8	+	27260156	PANC0327	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.6529909392527491	[551]	[847,719,853,674]	8	hSpCas9	negative selection	7789985
431385	431408	8	+	27260156	PANC0327	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.25533970193335254	[158]	[52,18,271,136]	-4	hSpCas9	negative selection	7789986
432914	432937	8	-	27260156	PANC0327	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5215752850328084	[1022]	[1424,1061,1412,1358]	7	hSpCas9	negative selection	7789987
450013	450036	8	-	27260156	NCIH2009	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	1.1133825317324473	[196]	[686,459,658]	9	hSpCas9	negative selection	7846972
463072	463095	8	+	27260156	NCIH2009	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.8755173589747312	[299]	[593,828,846]	9	hSpCas9	negative selection	7846973
463085	463108	8	-	27260156	NCIH2009	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.6474798489966915	[1052]	[2970,1832,2245]	8	hSpCas9	negative selection	7846974
450011	450034	8	+	27260156	NCIH2009	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.6232704351435917	[551]	[1324,856,1412]	8	hSpCas9	negative selection	7911236
431385	431408	8	+	27260156	NCIH2009	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-1.06706667897968	[158]	[86,113,112]	-8	hSpCas9	negative selection	7911237
432914	432937	8	-	27260156	NCIH2009	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5939422680319584	[1022]	[2360,1912,2238]	7	hSpCas9	negative selection	7911238
450013	450036	8	-	27260156	NCIH1373	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3896692072462663	[196]	[228,142,359,114]	4	hSpCas9	negative selection	7968223
463072	463095	8	+	27260156	NCIH1373	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.3758380282969091	[299]	[549,432,345,113]	3	hSpCas9	negative selection	7968224
463085	463108	8	-	27260156	NCIH1373	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.7696218806887138	[1052]	[2606,1747,1893,500]	7	hSpCas9	negative selection	7968225
450011	450034	8	+	27260156	NCIH1373	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.6429734597021639	[551]	[570,852,520,507]	6	hSpCas9	negative selection	8032487
431385	431408	8	+	27260156	NCIH1373	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.5525607417235925	[158]	[139,302,54,142]	5	hSpCas9	negative selection	8032488
432914	432937	8	-	27260156	NCIH1373	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	1.152435427121432	[1022]	[2399,2912,2387,633]	9	hSpCas9	negative selection	8032489
450013	450036	8	-	27260156	PATU8902	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.2870334939041911	[196]	[288,426,435,134]	3	hSpCas9	negative selection	8089474
463072	463095	8	+	27260156	PATU8902	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.013310900129155034	[299]	[264,217,496,720]	0	hSpCas9	negative selection	8089475
463085	463108	8	-	27260156	PATU8902	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.31587762826517984	[1052]	[2072,1672,1131,2688]	3	hSpCas9	negative selection	8089476
450011	450034	8	+	27260156	PATU8902	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.10590695569761344	[551]	[891,892,660,908]	1	hSpCas9	negative selection	8153738
431385	431408	8	+	27260156	PATU8902	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.33769921567044925	[158]	[222,163,415,278]	3	hSpCas9	negative selection	8153739
432914	432937	8	-	27260156	PATU8902	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.930900218342678	[1022]	[2964,3232,2031,2798]	8	hSpCas9	negative selection	8153740
450013	450036	8	-	27260156	PANC1	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.20262118771736182	[196]	[162,184,178,77]	-3	hSpCas9	negative selection	8210725
463072	463095	8	+	27260156	PANC1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.33271873166478116	[299]	[229,259,188,154]	-5	hSpCas9	negative selection	8210726
463085	463108	8	-	27260156	PANC1	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.12092320962329861	[1052]	[945,1315,1065,705]	2	hSpCas9	negative selection	8210727
450011	450034	8	+	27260156	PANC1	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.40525658811350396	[551]	[683,761,677,435]	6	hSpCas9	negative selection	8274989
431385	431408	8	+	27260156	PANC1	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.05910366293246638	[158]	[105,140,160,118]	-1	hSpCas9	negative selection	8274990
432914	432937	8	-	27260156	PANC1	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.635293930379252	[1022]	[1401,1443,1328,1288]	8	hSpCas9	negative selection	8274991
450013	450036	8	-	27260156	PANC0813	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.58863169293962	[196]	[362,463,215,348]	8	hSpCas9	negative selection	8331976
463072	463095	8	+	27260156	PANC0813	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.29691786119576025	[299]	[439,413,535,346]	5	hSpCas9	negative selection	8331977
463085	463108	8	-	27260156	PANC0813	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.45690635024026105	[1052]	[2015,1626,1842,1351]	7	hSpCas9	negative selection	8331978
450011	450034	8	+	27260156	PANC0813	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.10502000039138121	[551]	[656,849,752,533]	1	hSpCas9	negative selection	8396240
431385	431408	8	+	27260156	PANC0813	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.1468125605250159	[158]	[149,170,99,246]	-2	hSpCas9	negative selection	8396241
432914	432937	8	-	27260156	PANC0813	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5042342239128785	[1022]	[1912,1797,1818,1325]	7	hSpCas9	negative selection	8396242
450013	450036	8	-	27260156	RDES	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.27146394975651367	[196]	[229,178,304,412]	4	hSpCas9	negative selection	8453227
463072	463095	8	+	27260156	RDES	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.025238915151386432	[299]	[218,332,422,412]	0	hSpCas9	negative selection	8453228
463085	463108	8	-	27260156	RDES	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.09327684198793174	[1052]	[969,1281,1481,1505]	1	hSpCas9	negative selection	8453229
450011	450034	8	+	27260156	RDES	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.0014031565665439671	[551]	[467,580,755,787]	0	hSpCas9	negative selection	8517491
431385	431408	8	+	27260156	RDES	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.01616908710519649	[158]	[126,161,175,301]	0	hSpCas9	negative selection	8517492
432914	432937	8	-	27260156	RDES	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.9399463212176871	[1022]	[1805,2294,2358,2657]	9	hSpCas9	negative selection	8517493
450013	450036	8	-	27260156	PC3	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	-0.042784474437097764	[196]	[79,170,243,330]	-1	hSpCas9	negative selection	8574478
463072	463095	8	+	27260156	PC3	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.006683345569658661	[299]	[168,362,474,288]	0	hSpCas9	negative selection	8574479
463085	463108	8	-	27260156	PC3	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.051790519237527644	[1052]	[616,1029,1725,1031]	-1	hSpCas9	negative selection	8574480
450011	450034	8	+	27260156	PC3	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.12009021459606561	[551]	[449,718,760,508]	2	hSpCas9	negative selection	8638742
431385	431408	8	+	27260156	PC3	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.46449687087699587	[158]	[103,63,317,41]	-8	hSpCas9	negative selection	8638743
432914	432937	8	-	27260156	PC3	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5646285568729301	[1022]	[892,1539,2138,1847]	9	hSpCas9	negative selection	8638744
450013	450036	8	-	27260156	PATU8988T	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.3085291786593559	[196]	[334,119,192,288]	5	hSpCas9	negative selection	8695729
463072	463095	8	+	27260156	PATU8988T	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.5682708736157405	[299]	[572,388,411,333]	8	hSpCas9	negative selection	8695730
463085	463108	8	-	27260156	PATU8988T	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.2072830388921869	[1052]	[1004,1492,1214,1000]	3	hSpCas9	negative selection	8695731
450011	450034	8	+	27260156	PATU8988T	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.3687966744229745	[551]	[746,538,704,754]	6	hSpCas9	negative selection	8759993
431385	431408	8	+	27260156	PATU8988T	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.18303190178034456	[158]	[102,81,216,132]	-3	hSpCas9	negative selection	8759994
432914	432937	8	-	27260156	PATU8988T	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6608659869427207	[1022]	[1462,1665,1322,1833]	9	hSpCas9	negative selection	8759995
450013	450036	8	-	27260156	T47D	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.17879291975356915	[196]	[239,244,247,308]	4	hSpCas9	negative selection	8816980
463072	463095	8	+	27260156	T47D	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.01036941572287775	[299]	[315,491,285,300]	0	hSpCas9	negative selection	8816981
463085	463108	8	-	27260156	T47D	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.06660934413284503	[1052]	[1352,1087,1275,1443]	1	hSpCas9	negative selection	8816982
450011	450034	8	+	27260156	T47D	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.25453071975992025	[551]	[792,752,712,812]	5	hSpCas9	negative selection	8881244
431385	431408	8	+	27260156	T47D	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.18383215548560328	[158]	[170,124,176,182]	-4	hSpCas9	negative selection	8881245
432914	432937	8	-	27260156	T47D	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.5973409675641039	[1022]	[1839,1800,1657,1918]	9	hSpCas9	negative selection	8881246
450013	450036	8	-	27260156	SU8686	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.28146302462173944	[196]	[241,244,188,274]	5	hSpCas9	negative selection	8938231
463072	463095	8	+	27260156	SU8686	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.4678830522765107	[299]	[419,260,476,522]	7	hSpCas9	negative selection	8938232
463085	463108	8	-	27260156	SU8686	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.31534158581254634	[1052]	[1391,1119,1244,1467]	5	hSpCas9	negative selection	8938233
450011	450034	8	+	27260156	SU8686	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.17469556041528822	[551]	[539,459,668,868]	3	hSpCas9	negative selection	9002495
431385	431408	8	+	27260156	SU8686	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.6841504257683373	[158]	[82,84,98,133]	-7	hSpCas9	negative selection	9002496
432914	432937	8	-	27260156	SU8686	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6171334592838689	[1022]	[1362,1474,1745,1685]	8	hSpCas9	negative selection	9002497
450013	450036	8	-	27260156	SKES1	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.05969373216946883	[196]	[258,206,169,190]	1	hSpCas9	negative selection	9059482
463072	463095	8	+	27260156	SKES1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.09981575305317181	[299]	[294,242,297,275]	-2	hSpCas9	negative selection	9059483
463085	463108	8	-	27260156	SKES1	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	-0.022297039792270157	[1052]	[1287,1286,954,702]	0	hSpCas9	negative selection	9059484
450011	450034	8	+	27260156	SKES1	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.0081263586855298	[551]	[447,711,564,473]	0	hSpCas9	negative selection	9123746
431385	431408	8	+	27260156	SKES1	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.23139784669323338	[158]	[125,95,128,176]	-5	hSpCas9	negative selection	9123747
432914	432937	8	-	27260156	SKES1	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6366568162361312	[1022]	[1616,1885,1495,1394]	9	hSpCas9	negative selection	9123748
450013	450036	8	-	27260156	TOV112D	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.15906356135362953	[196]	[303,273,134,188]	3	hSpCas9	negative selection	9180733
463072	463095	8	+	27260156	TOV112D	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.05387420676435395	[299]	[361,525,140,275]	1	hSpCas9	negative selection	9180734
463085	463108	8	-	27260156	TOV112D	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.10956341731419417	[1052]	[1313,1155,1040,1059]	2	hSpCas9	negative selection	9180735
450011	450034	8	+	27260156	TOV112D	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.3365195216925331	[551]	[636,669,586,879]	6	hSpCas9	negative selection	9244997
431385	431408	8	+	27260156	TOV112D	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.9516592860728337	[158]	[48,82,127,66]	-9	hSpCas9	negative selection	9244998
432914	432937	8	-	27260156	TOV112D	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.6554050094301431	[1022]	[1788,1875,1334,1533]	9	hSpCas9	negative selection	9244999
450013	450036	8	-	27260156	TC71	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.021450546565885187	[196]	[182,207,169,303]	0	hSpCas9	negative selection	9301984
463072	463095	8	+	27260156	TC71	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.07943685740805906	[299]	[361,278,320,400]	2	hSpCas9	negative selection	9301985
463085	463108	8	-	27260156	TC71	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.1556642888641635	[1052]	[925,1310,1509,1282]	4	hSpCas9	negative selection	9301986
450011	450034	8	+	27260156	TC71	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	0.17545894975723791	[551]	[783,593,681,605]	4	hSpCas9	negative selection	9366248
431385	431408	8	+	27260156	TC71	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	-0.7131765819493436	[158]	[134,84,116,75]	-9	hSpCas9	negative selection	9366249
432914	432937	8	-	27260156	TC71	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.7790481006560657	[1022]	[1827,1980,1733,1996]	9	hSpCas9	negative selection	9366250
450013	450036	8	-	27260156	TC32	viability	CGCCACTCAATGAAGTTAACTGG	FBXO25	ENSG00000147364	0.6967966379259664	[196]	[212,264,257,472]	9	hSpCas9	negative selection	9423235
463072	463095	8	+	27260156	TC32	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.4827115709353661	[299]	[111,247,266,169]	-7	hSpCas9	negative selection	9423236
463085	463108	8	-	27260156	TC32	viability	TCTCCGTACTGCTCCTTCGCTGG	FBXO25	ENSG00000147364	0.02667238278778905	[1052]	[953,702,1156,1324]	0	hSpCas9	negative selection	9423237
450011	450034	8	+	27260156	TC32	viability	TCCCAGTTAACTTCATTGAGTGG	FBXO25	ENSG00000147364	-0.29535821710522037	[551]	[293,285,771,445]	-5	hSpCas9	negative selection	9487499
431385	431408	8	+	27260156	TC32	viability	ATGAATATGCATCGAAAAAAAGG	FBXO25	ENSG00000147364	0.015400205112844345	[158]	[160,171,126,117]	0	hSpCas9	negative selection	9487500
432914	432937	8	-	27260156	TC32	viability	CTTCCTTTGTGCTTTCTTTATGG	FBXO25	ENSG00000147364	0.8762524456365655	[1022]	[1814,1210,2055,2146]	9	hSpCas9	negative selection	9487501
458431	458454	8	-	27869803	HPAFII	viability after 27 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-1.2491359955775108	[812]	[283,92,NaN]	-7	hSpCas9	negative selection	9602660
458449	458472	8	+	27869803	HPAFII	viability after 27 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-1.2663900210332597	[98]	[31,12,NaN]	-7	hSpCas9	negative selection	9602661
463072	463095	8	+	27869803	HPAFII	viability after 27 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.134969605876335	[530]	[371,251,NaN]	1	hSpCas9	negative selection	9602668
468763	468786	8	-	27869803	HPAFII	viability after 27 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-1.7559744736771576	[277]	[93,0,NaN]	-8	hSpCas9	negative selection	9602692
458431	458454	8	-	27869803	HPAFII	viability after 15 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.7681863451901838	[812]	[652,425,NaN]	-7	hSpCas9	negative selection	9685109
458449	458472	8	+	27869803	HPAFII	viability after 15 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.09785882134112467	[98]	[103,119,NaN]	1	hSpCas9	negative selection	9685110
463072	463095	8	+	27869803	HPAFII	viability after 15 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.293860175400535	[530]	[1129,431,NaN]	3	hSpCas9	negative selection	9685117
468763	468786	8	-	27869803	HPAFII	viability after 15 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-1.0226015865430216	[277]	[307,46,NaN]	-8	hSpCas9	negative selection	9685141
458431	458454	8	-	27869803	ASPC1	viability after 36 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.11083570159674516	[1748]	[1160,398,506]	1	hSpCas9	negative selection	9767558
458449	458472	8	+	27869803	ASPC1	viability after 36 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.9761121499380871	[495]	[276,62,601]	8	hSpCas9	negative selection	9767559
463072	463095	8	+	27869803	ASPC1	viability after 36 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.429140748397592	[1265]	[662,773,398]	4	hSpCas9	negative selection	9767566
468763	468786	8	-	27869803	ASPC1	viability after 36 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.3607675708505794	[594]	[233,263,288]	3	hSpCas9	negative selection	9767590
458431	458454	8	-	27869803	PATU8988S	viability after 35 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.05441517160534981	[1497]	[630,621,NaN]	0	hSpCas9	negative selection	9850007
458449	458472	8	+	27869803	PATU8988S	viability after 35 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.13633312415611457	[447]	[116,279,NaN]	1	hSpCas9	negative selection	9850008
463072	463095	8	+	27869803	PATU8988S	viability after 35 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.05279419661707441	[1182]	[367,620,NaN]	0	hSpCas9	negative selection	9850015
468763	468786	8	-	27869803	PATU8988S	viability after 35 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.7763097587649139	[527]	[459,267,NaN]	8	hSpCas9	negative selection	9850039
458431	458454	8	-	27869803	PATU8988S	viability after 31 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	0.06295837394893522	[1497]	[630,614,NaN]	0	hSpCas9	negative selection	9932456
458449	458472	8	+	27869803	PATU8988S	viability after 31 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.18723345286737286	[447]	[165,250,NaN]	2	hSpCas9	negative selection	9932457
463072	463095	8	+	27869803	PATU8988S	viability after 31 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.007918543488100838	[1182]	[330,644,NaN]	0	hSpCas9	negative selection	9932464
468763	468786	8	-	27869803	PATU8988S	viability after 31 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	0.7519225101872524	[527]	[504,162,NaN]	8	hSpCas9	negative selection	9932488
458431	458454	8	-	27869803	HPAFII	viability after 35 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.39443948298068077	[812]	[322,301,NaN]	-2	hSpCas9	negative selection	10014905
458449	458472	8	+	27869803	HPAFII	viability after 35 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.8890053446851087	[98]	[35,16,NaN]	-5	hSpCas9	negative selection	10014906
463072	463095	8	+	27869803	HPAFII	viability after 35 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.02550230120786634	[530]	[241,288,NaN]	0	hSpCas9	negative selection	10014913
468763	468786	8	-	27869803	HPAFII	viability after 35 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-1.160296886190488	[277]	[117,0,NaN]	-6	hSpCas9	negative selection	10014937
458431	458454	8	-	27869803	HPAFII	viability after 31 days	TGTCCCATCCGTCTGAGAACCGG	FBXO25	ENSG00000147364	-0.43744137892777735	[812]	[446,216,NaN]	-3	hSpCas9	negative selection	10097354
458449	458472	8	+	27869803	HPAFII	viability after 31 days	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	-0.26126567446281745	[98]	[31,61,NaN]	-2	hSpCas9	negative selection	10097355
463072	463095	8	+	27869803	HPAFII	viability after 31 days	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.22507856822501182	[530]	[388,303,NaN]	1	hSpCas9	negative selection	10097362
468763	468786	8	-	27869803	HPAFII	viability after 31 days	ATGAAGTGCTGCGGAGACACAGG	FBXO25	ENSG00000147364	-2.419792422960497	[277]	[54,0,NaN]	-8	hSpCas9	negative selection	10097386
458493	458516	8	+	28162770	P31FUJ	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.3039221958012064	[394]	[187]	-7	hSpCas9	negative selection	10155994
458427	458450	8	+	28162770	P31FUJ	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.05096388142856545	[401]	[455]	0	hSpCas9	negative selection	10155995
458383	458406	8	-	28162770	P31FUJ	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.3886861723318915	[168]	[259]	4	hSpCas9	negative selection	10155996
458402	458425	8	-	28162770	P31FUJ	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	-0.3668195523860662	[123]	[112]	-3	hSpCas9	negative selection	10155997
458449	458472	8	+	28162770	P31FUJ	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.7149539280342108	[238]	[460]	7	hSpCas9	negative selection	10155998
463072	463095	8	+	28162770	P31FUJ	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.5475755802197936	[351]	[282]	-4	hSpCas9	negative selection	10155999
463104	463127	8	+	28162770	P31FUJ	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.5270637918619063	[74]	[126]	6	hSpCas9	negative selection	10156000
450016	450039	8	+	28162770	P31FUJ	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7709499304467288	[191]	[384]	8	hSpCas9	negative selection	10156001
451432	451455	8	+	28162770	P31FUJ	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-0.4641277505208343	[26]	[22]	-4	hSpCas9	negative selection	10156002
458493	458516	8	+	28162770	TF1	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10325360
458427	458450	8	+	28162770	TF1	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10325361
458383	458406	8	-	28162770	TF1	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10325362
458402	458425	8	-	28162770	TF1	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10325363
458449	458472	8	+	28162770	TF1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	NaN	[NaN]	[431]	1	hSpCas9	negative selection	10325364
463072	463095	8	+	28162770	TF1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10325365
463104	463127	8	+	28162770	TF1	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10325366
450016	450039	8	+	28162770	TF1	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10325367
451432	451455	8	+	28162770	TF1	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10325368
458493	458516	8	+	28162770	SKM1	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.44832322850421924	[114]	[148]	-4	hSpCas9	negative selection	10494726
458427	458450	8	+	28162770	SKM1	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.14192904727047284	[80]	[157]	1	hSpCas9	negative selection	10494727
458383	458406	8	-	28162770	SKM1	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.4821516951373809	[48]	[120]	5	hSpCas9	negative selection	10494728
458402	458425	8	-	28162770	SKM1	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10494729
458449	458472	8	+	28162770	SKM1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.6197037517189183	[66]	[181]	6	hSpCas9	negative selection	10494730
463072	463095	8	+	28162770	SKM1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.25694964337281634	[79]	[168]	2	hSpCas9	negative selection	10494731
463104	463127	8	+	28162770	SKM1	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.8220016980220055	[24]	[24]	-6	hSpCas9	negative selection	10494732
450016	450039	8	+	28162770	SKM1	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7505770782433183	[38]	[115]	7	hSpCas9	negative selection	10494733
451432	451455	8	+	28162770	SKM1	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	1.663425129148236	[4]	[27]	9	hSpCas9	negative selection	10494734
458493	458516	8	+	28162770	SKM1	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.44832322850421924	[114]	[148]	-4	hSpCas9	negative selection	10664092
458427	458450	8	+	28162770	SKM1	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.14192904727047284	[80]	[157]	1	hSpCas9	negative selection	10664093
458383	458406	8	-	28162770	SKM1	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.4821516951373809	[48]	[120]	5	hSpCas9	negative selection	10664094
458402	458425	8	-	28162770	SKM1	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10664095
458449	458472	8	+	28162770	SKM1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.6197037517189183	[66]	[181]	6	hSpCas9	negative selection	10664096
463072	463095	8	+	28162770	SKM1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.25694964337281634	[79]	[168]	2	hSpCas9	negative selection	10664097
463104	463127	8	+	28162770	SKM1	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.8220016980220055	[24]	[24]	-6	hSpCas9	negative selection	10664098
450016	450039	8	+	28162770	SKM1	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7505770782433183	[38]	[115]	7	hSpCas9	negative selection	10664099
451432	451455	8	+	28162770	SKM1	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	1.663425129148236	[4]	[27]	9	hSpCas9	negative selection	10664100
458493	458516	8	+	28162770	PL21	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.2003983150944086	[395]	[74]	-7	hSpCas9	negative selection	10833458
458427	458450	8	+	28162770	PL21	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.770228838728946	[259]	[192]	6	hSpCas9	negative selection	10833459
458383	458406	8	-	28162770	PL21	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.240781598986666	[209]	[107]	2	hSpCas9	negative selection	10833460
458402	458425	8	-	28162770	PL21	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.30532185118137656	[118]	[63]	2	hSpCas9	negative selection	10833461
458449	458472	8	+	28162770	PL21	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.7876443097729294	[377]	[283]	6	hSpCas9	negative selection	10833462
463072	463095	8	+	28162770	PL21	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.38957641620247074	[303]	[100]	-3	hSpCas9	negative selection	10833463
463104	463127	8	+	28162770	PL21	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.6072153075682838	[76]	[21]	-4	hSpCas9	negative selection	10833464
450016	450039	8	+	28162770	PL21	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.7366665590234858	[133]	[34]	-5	hSpCas9	negative selection	10833465
451432	451455	8	+	28162770	PL21	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-3.1217884803980427	[19]	[0]	-9	hSpCas9	negative selection	10833466
458493	458516	8	+	28162770	P31FUJ	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.3039221958012064	[394]	[187]	-7	hSpCas9	negative selection	11002824
458427	458450	8	+	28162770	P31FUJ	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.05096388142856545	[401]	[455]	0	hSpCas9	negative selection	11002825
458383	458406	8	-	28162770	P31FUJ	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.3886861723318915	[168]	[259]	4	hSpCas9	negative selection	11002826
458402	458425	8	-	28162770	P31FUJ	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	-0.3668195523860662	[123]	[112]	-3	hSpCas9	negative selection	11002827
458449	458472	8	+	28162770	P31FUJ	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.7149539280342108	[238]	[460]	7	hSpCas9	negative selection	11002828
463072	463095	8	+	28162770	P31FUJ	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.5475755802197936	[351]	[282]	-4	hSpCas9	negative selection	11002829
463104	463127	8	+	28162770	P31FUJ	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.5270637918619063	[74]	[126]	6	hSpCas9	negative selection	11002830
450016	450039	8	+	28162770	P31FUJ	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7709499304467288	[191]	[384]	8	hSpCas9	negative selection	11002831
451432	451455	8	+	28162770	P31FUJ	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-0.4641277505208343	[26]	[22]	-4	hSpCas9	negative selection	11002832
458493	458516	8	+	28162770	OCIAML5	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.4291238734998069	[181]	[121]	-7	hSpCas9	negative selection	11172190
458427	458450	8	+	28162770	OCIAML5	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.23252360117203608	[206]	[438]	2	hSpCas9	negative selection	11172191
458383	458406	8	-	28162770	OCIAML5	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.48328203978568707	[106]	[269]	4	hSpCas9	negative selection	11172192
458402	458425	8	-	28162770	OCIAML5	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.27917796241425585	[41]	[91]	2	hSpCas9	negative selection	11172193
458449	458472	8	+	28162770	OCIAML5	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.7882033015362563	[144]	[451]	7	hSpCas9	negative selection	11172194
463072	463095	8	+	28162770	OCIAML5	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.580285513717016	[175]	[474]	5	hSpCas9	negative selection	11172195
463104	463127	8	+	28162770	OCIAML5	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	1.8177848274436723	[32]	[209]	9	hSpCas9	negative selection	11172196
450016	450039	8	+	28162770	OCIAML5	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.05851744833142328	[104]	[181]	0	hSpCas9	negative selection	11172197
451432	451455	8	+	28162770	OCIAML5	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-4.021991572306309	[8]	[0]	-9	hSpCas9	negative selection	11172198
458493	458516	8	+	28162770	EOL1	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.4572604998834644	[700]	[268]	-3	hSpCas9	negative selection	11341556
458427	458450	8	+	28162770	EOL1	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.10365609517818233	[347]	[196]	0	hSpCas9	negative selection	11341557
458383	458406	8	-	28162770	EOL1	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	-0.40757609042271625	[354]	[140]	-3	hSpCas9	negative selection	11341558
458402	458425	8	-	28162770	EOL1	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	-0.43054718725202723	[219]	[85]	-3	hSpCas9	negative selection	11341559
458449	458472	8	+	28162770	EOL1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.5203796575403546	[572]	[432]	5	hSpCas9	negative selection	11341560
463072	463095	8	+	28162770	EOL1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.18830733200159555	[662]	[397]	1	hSpCas9	negative selection	11341561
463104	463127	8	+	28162770	EOL1	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-1.5183957242781938	[86]	[15]	-7	hSpCas9	negative selection	11341562
450016	450039	8	+	28162770	EOL1	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.4733291765501263	[194]	[73]	-4	hSpCas9	negative selection	11341563
451432	451455	8	+	28162770	EOL1	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	1.1261816327401855	[19]	[22]	8	hSpCas9	negative selection	11341564
458493	458516	8	+	28162770	MOLM13	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-2.258165438411177	[482]	[72]	-7	hSpCas9	negative selection	11510922
458427	458450	8	+	28162770	MOLM13	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.4642043347367229	[391]	[390]	3	hSpCas9	negative selection	11510923
458383	458406	8	-	28162770	MOLM13	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	1.372892867608832	[203]	[381]	9	hSpCas9	negative selection	11510924
458402	458425	8	-	28162770	MOLM13	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	-0.24774207094275136	[178]	[108]	-1	hSpCas9	negative selection	11510925
458449	458472	8	+	28162770	MOLM13	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.42507629800560576	[512]	[497]	3	hSpCas9	negative selection	11510926
463072	463095	8	+	28162770	MOLM13	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.3211229603912227	[507]	[293]	-2	hSpCas9	negative selection	11510927
463104	463127	8	+	28162770	MOLM13	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.05285188226573512	[99]	[74]	0	hSpCas9	negative selection	11510928
450016	450039	8	+	28162770	MOLM13	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.27044331733836174	[171]	[149]	2	hSpCas9	negative selection	11510929
451432	451455	8	+	28162770	MOLM13	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-4.28699812061889	[26]	[0]	-9	hSpCas9	negative selection	11510930
458493	458516	8	+	28162770	HEL	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.6164825207222373	[528]	[220]	-4	hSpCas9	negative selection	11680288
458427	458450	8	+	28162770	HEL	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.5168299347064516	[346]	[317]	4	hSpCas9	negative selection	11680289
458383	458406	8	-	28162770	HEL	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	1.0800379427513567	[208]	[282]	8	hSpCas9	negative selection	11680290
458402	458425	8	-	28162770	HEL	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	1.2277013327215132	[121]	[182]	9	hSpCas9	negative selection	11680291
458449	458472	8	+	28162770	HEL	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.8434361822374857	[401]	[461]	7	hSpCas9	negative selection	11680292
463072	463095	8	+	28162770	HEL	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.8826311580217079	[397]	[469]	7	hSpCas9	negative selection	11680293
463104	463127	8	+	28162770	HEL	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.7378960650406972	[87]	[93]	6	hSpCas9	negative selection	11680294
450016	450039	8	+	28162770	HEL	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.38474190442175027	[158]	[77]	-3	hSpCas9	negative selection	11680295
451432	451455	8	+	28162770	HEL	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	1.2801687526156487	[17]	[27]	9	hSpCas9	negative selection	11680296
458493	458516	8	+	28162770	MV411	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-1.6339179527186056	[419]	[113]	-7	hSpCas9	negative selection	11849654
458427	458450	8	+	28162770	MV411	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.8840895285154322	[264]	[411]	7	hSpCas9	negative selection	11849655
458383	458406	8	-	28162770	MV411	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	-0.11082275679081185	[190]	[148]	-1	hSpCas9	negative selection	11849656
458402	458425	8	-	28162770	MV411	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.4872645654552438	[93]	[110]	4	hSpCas9	negative selection	11849657
458449	458472	8	+	28162770	MV411	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.06576359066138238	[261]	[230]	0	hSpCas9	negative selection	11849658
463072	463095	8	+	28162770	MV411	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.570851533397202	[297]	[168]	-4	hSpCas9	negative selection	11849659
463104	463127	8	+	28162770	MV411	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.9902797112856506	[48]	[81]	8	hSpCas9	negative selection	11849660
450016	450039	8	+	28162770	MV411	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.5270116327665004	[158]	[192]	5	hSpCas9	negative selection	11849661
451432	451455	8	+	28162770	MV411	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-2.211994067854522	[32]	[5]	-8	hSpCas9	negative selection	11849662
458493	458516	8	+	28162770	MONOMAC1	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.3345403708094886	[241]	[219]	-3	hSpCas9	negative selection	12019020
458427	458450	8	+	28162770	MONOMAC1	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	-0.06377031619608942	[185]	[203]	0	hSpCas9	negative selection	12019021
458383	458406	8	-	28162770	MONOMAC1	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.694149665801521	[116]	[216]	6	hSpCas9	negative selection	12019022
458402	458425	8	-	28162770	MONOMAC1	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.25042212991166757	[65]	[89]	2	hSpCas9	negative selection	12019023
458449	458472	8	+	28162770	MONOMAC1	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.42024337393433087	[205]	[315]	4	hSpCas9	negative selection	12019024
463072	463095	8	+	28162770	MONOMAC1	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.4241079899682486	[209]	[322]	4	hSpCas9	negative selection	12019025
463104	463127	8	+	28162770	MONOMAC1	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	0.7833343461915135	[36]	[72]	7	hSpCas9	negative selection	12019026
450016	450039	8	+	28162770	MONOMAC1	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	1.210840860646424	[100]	[267]	9	hSpCas9	negative selection	12019027
451432	451455	8	+	28162770	MONOMAC1	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	0.5684978993034235	[9]	[16]	5	hSpCas9	negative selection	12019028
458493	458516	8	+	28162770	OCIAML2	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.8653473401414089	[46]	[142]	-6	hSpCas9	negative selection	12188386
458427	458450	8	+	28162770	OCIAML2	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.6676731970269261	[40]	[360]	6	hSpCas9	negative selection	12188387
458383	458406	8	-	28162770	OCIAML2	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.67776201465051	[29]	[265]	6	hSpCas9	negative selection	12188388
458402	458425	8	-	28162770	OCIAML2	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	-0.7274052406042727	[22]	[76]	-5	hSpCas9	negative selection	12188389
458449	458472	8	+	28162770	OCIAML2	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.1838736087320718	[53]	[339]	1	hSpCas9	negative selection	12188390
463072	463095	8	+	28162770	OCIAML2	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	-0.45270791724489867	[79]	[323]	-4	hSpCas9	negative selection	12188391
463104	463127	8	+	28162770	OCIAML2	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	-0.12270652182185438	[10]	[55]	-1	hSpCas9	negative selection	12188392
450016	450039	8	+	28162770	OCIAML2	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	-0.006348806943468177	[26]	[148]	0	hSpCas9	negative selection	12188393
451432	451455	8	+	28162770	OCIAML2	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	-3.4706298252421615	[3]	[1]	-9	hSpCas9	negative selection	12188394
458493	458516	8	+	28162770	OCIAML3	viability	TTAGTGAAGACAGACAGCTGTGG	FBXO25	ENSG00000147364	-0.6923455595174557	[128]	[240]	-5	hSpCas9	negative selection	12357752
458427	458450	8	+	28162770	OCIAML3	viability	TATACCGGTTCTCAGACGGATGG	FBXO25	ENSG00000147364	0.8799235480082491	[62]	[349]	7	hSpCas9	negative selection	12357753
458383	458406	8	-	28162770	OCIAML3	viability	GAGGAAGGTCACTGAGGGTGAGG	FBXO25	ENSG00000147364	0.6232230758965058	[39]	[185]	5	hSpCas9	negative selection	12357754
458402	458425	8	-	28162770	OCIAML3	viability	ATGTTGTTCAGCATGTGCAGAGG	FBXO25	ENSG00000147364	0.9405813378818737	[33]	[196]	7	hSpCas9	negative selection	12357755
458449	458472	8	+	28162770	OCIAML3	viability	GGACATCATCACCTTAGGCCAGG	FBXO25	ENSG00000147364	0.707161894396402	[69]	[344]	6	hSpCas9	negative selection	12357756
463072	463095	8	+	28162770	OCIAML3	viability	TCAGAAACATTACCCAGCGAAGG	FBXO25	ENSG00000147364	0.375618710632318	[95]	[375]	3	hSpCas9	negative selection	12357757
463104	463127	8	+	28162770	OCIAML3	viability	GAGACACACTGCATTTCTGTCGG	FBXO25	ENSG00000147364	1.3953451154763283	[16]	[134]	9	hSpCas9	negative selection	12357758
450016	450039	8	+	28162770	OCIAML3	viability	GTTAACTTCATTGAGTGGCGTGG	FBXO25	ENSG00000147364	0.7113375703675952	[34]	[172]	6	hSpCas9	negative selection	12357759
451432	451455	8	+	28162770	OCIAML3	viability	ACAGGATCTTCAGATGACTAAGG	FBXO25	ENSG00000147364	0.90849270020502	[5]	[33]	7	hSpCas9	negative selection	12357760