Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9896
• Symbol: FIG4
• Description: FIG4 phosphoinositide 5-phosphatase

DataSource: http://genomecrispr.dkfz.de/#!/results/FIG4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109765057	109765080	6	+	26472758	Jiyoye	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.8394908722165528	[165]	[223]	6	hSpCas9	negative selection	58188
109743109	109743132	6	+	26472758	Jiyoye	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.2419174566349982	[137]	[43]	-7	hSpCas9	negative selection	58189
109766771	109766794	6	-	26472758	Jiyoye	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	1.0485633156898486	[233]	[364]	7	hSpCas9	negative selection	58190
109776957	109776980	6	+	26472758	Jiyoye	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.0459972466597417	[229]	[167]	0	hSpCas9	negative selection	58191
109791390	109791413	6	+	26472758	Jiyoye	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	1.0748783132349657	[191]	[304]	7	hSpCas9	negative selection	58192
109743714	109743737	6	+	26472758	Jiyoye	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	-0.5928246184941264	[323]	[161]	-4	hSpCas9	negative selection	58193
109776984	109777007	6	-	26472758	Jiyoye	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.7271257102057178	[89]	[40]	-5	hSpCas9	negative selection	58194
109791550	109791573	6	+	26472758	Jiyoye	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.6188198270270712	[111]	[54]	-4	hSpCas9	negative selection	58195
109716527	109716550	6	-	26472758	Jiyoye	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	3.9921378822270293	[0]	[11]	9	hSpCas9	negative selection	58196
109735205	109735228	6	-	26472758	Jiyoye	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-0.27696252430611845	[285]	[177]	-2	hSpCas9	negative selection	58197
109765057	109765080	6	+	26472758	KBM7	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.20273005368914798	[785,711]	[551,273]	2	hSpCas9	negative selection	249306
109743109	109743132	6	+	26472758	KBM7	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.23311073907944674	[484,462]	[203,314]	2	hSpCas9	negative selection	249307
109766771	109766794	6	-	26472758	KBM7	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.2876388069843372	[1425,1259]	[860,687]	3	hSpCas9	negative selection	249308
109776957	109776980	6	+	26472758	KBM7	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	0.3977339479807755	[643,437]	[410,257]	4	hSpCas9	negative selection	249309
109791390	109791413	6	+	26472758	KBM7	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.4802493537025738	[1115,784]	[683,553]	5	hSpCas9	negative selection	249310
109743714	109743737	6	+	26472758	KBM7	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.8671656686245988	[643,526]	[433,557]	8	hSpCas9	negative selection	249311
109776984	109777007	6	-	26472758	KBM7	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.166571319809368	[528,375]	[119,69]	-7	hSpCas9	negative selection	249312
109791550	109791573	6	+	26472758	KBM7	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	1.020106143336653	[336,227]	[295,237]	9	hSpCas9	negative selection	249313
109716527	109716550	6	-	26472758	KBM7	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.2539492006420736	[44,40]	[21,25]	2	hSpCas9	negative selection	249314
109735205	109735228	6	-	26472758	KBM7	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.29619745754898374	[819,787]	[474,456]	3	hSpCas9	negative selection	249315
109765057	109765080	6	+	26472758	Raji	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.6030394948607277	[260]	[91]	6	hSpCas9	negative selection	440424
109743109	109743132	6	+	26472758	Raji	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.3928818007722752	[214]	[18]	-7	hSpCas9	negative selection	440425
109766771	109766794	6	-	26472758	Raji	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	-0.14113247289392805	[612]	[128]	-1	hSpCas9	negative selection	440426
109776957	109776980	6	+	26472758	Raji	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.031177295159377727	[272]	[61]	0	hSpCas9	negative selection	440427
109791390	109791413	6	+	26472758	Raji	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.5248846801259135	[433]	[69]	-4	hSpCas9	negative selection	440428
109743714	109743737	6	+	26472758	Raji	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.5392456572938021	[340]	[114]	5	hSpCas9	negative selection	440429
109776984	109777007	6	-	26472758	Raji	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.2725501629493283	[405]	[38]	-7	hSpCas9	negative selection	440430
109791550	109791573	6	+	26472758	Raji	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.12752149727639728	[192]	[40]	-1	hSpCas9	negative selection	440431
109716527	109716550	6	-	26472758	Raji	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	1.547956126759581	[27]	[18]	9	hSpCas9	negative selection	440432
109735205	109735228	6	-	26472758	Raji	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-0.8769858129126366	[458]	[57]	-6	hSpCas9	negative selection	440433
109765057	109765080	6	+	26472758	K562	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.8814932609068933	[579]	[901]	7	hSpCas9	negative selection	631542
109743109	109743132	6	+	26472758	K562	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.07261056780807634	[293]	[235]	0	hSpCas9	negative selection	631543
109766771	109766794	6	-	26472758	K562	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.02345826182313071	[1006]	[863]	0	hSpCas9	negative selection	631544
109776957	109776980	6	+	26472758	K562	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.5122038258677692	[467]	[276]	-3	hSpCas9	negative selection	631545
109791390	109791413	6	+	26472758	K562	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	1.0203979821832245	[590]	[1011]	8	hSpCas9	negative selection	631546
109743714	109743737	6	+	26472758	K562	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.751064984724576	[510]	[725]	6	hSpCas9	negative selection	631547
109776984	109777007	6	-	26472758	K562	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-7.1101979859270905	[490]	[2]	-9	hSpCas9	negative selection	631548
109791550	109791573	6	+	26472758	K562	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	0.7104401556640957	[277]	[383]	6	hSpCas9	negative selection	631549
109716527	109716550	6	-	26472758	K562	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	1.4814579249672963	[13]	[32]	9	hSpCas9	negative selection	631550
109735205	109735228	6	-	26472758	K562	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-0.17831689584396637	[688]	[513]	-1	hSpCas9	negative selection	631551
109716525	109716548	6	+	26627737	DLD1	viability	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.19584094551197823	[510]	[105,254,189]	2	hSpCas9	negative selection	830078
109743109	109743132	6	+	26627737	DLD1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.8070545412540933	[368]	[87,84,30]	-6	hSpCas9	negative selection	830079
109743689	109743712	6	-	26627737	DLD1	viability	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.9767634537712824	[606]	[371,372,374]	8	hSpCas9	negative selection	830080
109763950	109763973	6	+	26627737	DLD1	viability	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.11889577117216787	[154]	[68,43,23]	-1	hSpCas9	negative selection	830081
109766812	109766835	6	+	26627737	DLD1	viability	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.04146578337631257	[977]	[259,446,204]	0	hSpCas9	negative selection	830082
109786428	109786451	6	+	26627737	DLD1	viability	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.1287769443136344	[1050]	[372,264,266]	-1	hSpCas9	negative selection	830083
109716525	109716548	6	+	26627737	GBM cells	viability after 5 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.6280901209463293	[259]	[245,184]	8	hSpCas9	negative selection	912393
109743109	109743132	6	+	26627737	GBM cells	viability after 5 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.29202890782570984	[241]	[107,103]	-4	hSpCas9	negative selection	912394
109743689	109743712	6	-	26627737	GBM cells	viability after 5 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.5211895340748978	[457]	[359,344]	7	hSpCas9	negative selection	912395
109763950	109763973	6	+	26627737	GBM cells	viability after 5 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.060058856854259934	[103]	[46,59]	-1	hSpCas9	negative selection	912396
109766812	109766835	6	+	26627737	GBM cells	viability after 5 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.2283551942046862	[603]	[248,303]	-4	hSpCas9	negative selection	912397
109786428	109786451	6	+	26627737	GBM cells	viability after 5 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.4464016701881788	[350]	[300,211]	6	hSpCas9	negative selection	912398
109716525	109716548	6	+	26627737	GBM cells	viability after 13 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.5925511721166158	[259]	[204,218]	7	hSpCas9	negative selection	994708
109743109	109743132	6	+	26627737	GBM cells	viability after 13 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.09441595566699083	[241]	[164,119]	1	hSpCas9	negative selection	994709
109743689	109743712	6	-	26627737	GBM cells	viability after 13 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.26803587309379284	[457]	[360,248]	3	hSpCas9	negative selection	994710
109763950	109763973	6	+	26627737	GBM cells	viability after 13 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	0.2394958991206133	[103]	[59,71]	3	hSpCas9	negative selection	994711
109766812	109766835	6	+	26627737	GBM cells	viability after 13 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.2786611838396471	[603]	[305,240]	-3	hSpCas9	negative selection	994712
109786428	109786451	6	+	26627737	GBM cells	viability after 13 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.556551352858073	[350]	[337,232]	7	hSpCas9	negative selection	994713
109716525	109716548	6	+	26627737	GBM cells	viability after 21 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	1.039707929104784	[259]	[292,287]	8	hSpCas9	negative selection	1077023
109743109	109743132	6	+	26627737	GBM cells	viability after 21 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.23844904848906784	[241]	[100,120]	-2	hSpCas9	negative selection	1077024
109743689	109743712	6	-	26627737	GBM cells	viability after 21 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.09009147192001066	[457]	[279,250]	0	hSpCas9	negative selection	1077025
109763950	109763973	6	+	26627737	GBM cells	viability after 21 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	0.19027506534288885	[103]	[76,52]	2	hSpCas9	negative selection	1077026
109766812	109766835	6	+	26627737	GBM cells	viability after 21 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.04394054260321223	[603]	[307,365]	0	hSpCas9	negative selection	1077027
109786428	109786451	6	+	26627737	GBM cells	viability after 21 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.6386853703428375	[350]	[322,272]	6	hSpCas9	negative selection	1077028
109716525	109716548	6	+	26627737	RPE1	viability after 9 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.46820683127718804	[944]	[205,223]	-3	hSpCas9	negative selection	1159338
109743109	109743132	6	+	26627737	RPE1	viability after 9 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.12151144050972153	[838]	[314,247]	0	hSpCas9	negative selection	1159339
109743689	109743712	6	-	26627737	RPE1	viability after 9 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.8717509850680284	[1409]	[750,880]	5	hSpCas9	negative selection	1159340
109763950	109763973	6	+	26627737	RPE1	viability after 9 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.515819858628129	[563]	[28,103]	-8	hSpCas9	negative selection	1159341
109766812	109766835	6	+	26627737	RPE1	viability after 9 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.4336857905619671	[1008]	[382,482]	3	hSpCas9	negative selection	1159342
109786428	109786451	6	+	26627737	RPE1	viability after 9 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.027606957601558513	[1421]	[372,518]	0	hSpCas9	negative selection	1159343
109716525	109716548	6	+	26627737	RPE1	viability after 12 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.4097672944532905	[944]	[194,186]	-3	hSpCas9	negative selection	1241653
109743109	109743132	6	+	26627737	RPE1	viability after 12 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.030328434478182745	[838]	[236,222]	0	hSpCas9	negative selection	1241654
109743689	109743712	6	-	26627737	RPE1	viability after 12 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	1.127172745370216	[1409]	[825,828]	6	hSpCas9	negative selection	1241655
109763950	109763973	6	+	26627737	RPE1	viability after 12 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.9391375165201281	[563]	[22,56]	-8	hSpCas9	negative selection	1241656
109766812	109766835	6	+	26627737	RPE1	viability after 12 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.3503603598428866	[1008]	[416,269]	2	hSpCas9	negative selection	1241657
109786428	109786451	6	+	26627737	RPE1	viability after 12 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.1307505782801609	[1421]	[410,425]	0	hSpCas9	negative selection	1241658
109716525	109716548	6	+	26627737	RPE1	viability after 15 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.9302738034432951	[944]	[208,73]	-5	hSpCas9	negative selection	1323968
109743109	109743132	6	+	26627737	RPE1	viability after 15 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.06206005380721222	[838]	[179,272]	0	hSpCas9	negative selection	1323969
109743689	109743712	6	-	26627737	RPE1	viability after 15 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.9050153678690728	[1409]	[696,794]	5	hSpCas9	negative selection	1323970
109763950	109763973	6	+	26627737	RPE1	viability after 15 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.8903995626900431	[563]	[25,143]	-5	hSpCas9	negative selection	1323971
109766812	109766835	6	+	26627737	RPE1	viability after 15 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.3151365100835567	[1008]	[517,197]	2	hSpCas9	negative selection	1323972
109786428	109786451	6	+	26627737	RPE1	viability after 15 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.2176195220861854	[1421]	[453,480]	1	hSpCas9	negative selection	1323973
109716525	109716548	6	+	26627737	RPE1	viability after 18 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.44093210564102714	[944]	[183,191]	-3	hSpCas9	negative selection	1406283
109743109	109743132	6	+	26627737	RPE1	viability after 18 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.043116348154742065	[838]	[197,270]	0	hSpCas9	negative selection	1406284
109743689	109743712	6	-	26627737	RPE1	viability after 18 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	1.3598225822763812	[1409]	[935,1019]	7	hSpCas9	negative selection	1406285
109763950	109763973	6	+	26627737	RPE1	viability after 18 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.3213892744173488	[563]	[28,94]	-7	hSpCas9	negative selection	1406286
109766812	109766835	6	+	26627737	RPE1	viability after 18 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.003163836009155041	[1008]	[196,353]	0	hSpCas9	negative selection	1406287
109786428	109786451	6	+	26627737	RPE1	viability after 18 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.14028238127675352	[1421]	[464,377]	0	hSpCas9	negative selection	1406288
109716525	109716548	6	+	26627737	HeLa	viability after 8 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.19252637847444803	[472]	[357,218,160]	1	hSpCas9	negative selection	1488598
109743109	109743132	6	+	26627737	HeLa	viability after 8 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.21874200295692509	[353]	[218,110,213]	2	hSpCas9	negative selection	1488599
109743689	109743712	6	-	26627737	HeLa	viability after 8 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.9300412711546281	[566]	[396,494,499]	7	hSpCas9	negative selection	1488600
109763950	109763973	6	+	26627737	HeLa	viability after 8 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	1.1727167282564013	[63]	[91,72,31]	8	hSpCas9	negative selection	1488601
109766812	109766835	6	+	26627737	HeLa	viability after 8 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.5789991810945226	[865]	[206,156,373]	-5	hSpCas9	negative selection	1488602
109786428	109786451	6	+	26627737	HeLa	viability after 8 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.9759118944326024	[520]	[575,457,339]	7	hSpCas9	negative selection	1488603
109716525	109716548	6	+	26627737	HeLa	viability after 12 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.3778866691270844	[472]	[319,243,200]	3	hSpCas9	negative selection	1570913
109743109	109743132	6	+	26627737	HeLa	viability after 12 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.4348375166663101	[353]	[130,181,279]	4	hSpCas9	negative selection	1570914
109743689	109743712	6	-	26627737	HeLa	viability after 12 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.9058333019597272	[566]	[434,334,557]	7	hSpCas9	negative selection	1570915
109763950	109763973	6	+	26627737	HeLa	viability after 12 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	0.5234995203476625	[63]	[12,59,37]	4	hSpCas9	negative selection	1570916
109766812	109766835	6	+	26627737	HeLa	viability after 12 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.6829838078107247	[865]	[333,118,229]	-6	hSpCas9	negative selection	1570917
109786428	109786451	6	+	26627737	HeLa	viability after 12 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	1.0207990294853573	[520]	[517,398,399]	7	hSpCas9	negative selection	1570918
109716525	109716548	6	+	26627737	HeLa	viability after 15 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.03631638947494592	[472]	[175,154,266]	0	hSpCas9	negative selection	1653228
109743109	109743132	6	+	26627737	HeLa	viability after 15 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.2454562941670867	[353]	[153,208,147]	2	hSpCas9	negative selection	1653229
109743689	109743712	6	-	26627737	HeLa	viability after 15 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.4989254401879081	[566]	[346,308,321]	4	hSpCas9	negative selection	1653230
109763950	109763973	6	+	26627737	HeLa	viability after 15 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	0.5878776819093874	[63]	[14,36,67]	5	hSpCas9	negative selection	1653231
109766812	109766835	6	+	26627737	HeLa	viability after 15 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.10231467453274723	[865]	[246,415,481]	0	hSpCas9	negative selection	1653232
109786428	109786451	6	+	26627737	HeLa	viability after 15 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.7407767003211425	[520]	[311,443,303]	6	hSpCas9	negative selection	1653233
109716525	109716548	6	+	26627737	HeLa	viability after 18 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.058805689052348065	[472]	[113,140,266]	0	hSpCas9	negative selection	1735543
109743109	109743132	6	+	26627737	HeLa	viability after 18 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.26710866734105077	[353]	[109,170,147]	2	hSpCas9	negative selection	1735544
109743689	109743712	6	-	26627737	HeLa	viability after 18 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.46181373798128955	[566]	[218,252,321]	4	hSpCas9	negative selection	1735545
109763950	109763973	6	+	26627737	HeLa	viability after 18 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	0.636773325163142	[63]	[9,33,67]	5	hSpCas9	negative selection	1735546
109766812	109766835	6	+	26627737	HeLa	viability after 18 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.08992326119364202	[865]	[158,344,481]	0	hSpCas9	negative selection	1735547
109786428	109786451	6	+	26627737	HeLa	viability after 18 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.7651438124148042	[520]	[223,363,303]	6	hSpCas9	negative selection	1735548
109716525	109716548	6	+	26627737	HCT116	viability after 6 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.3027698223753619	[910]	[146,8]	-6	hSpCas9	negative selection	1817858
109743109	109743132	6	+	26627737	HCT116	viability after 6 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.6870250237790791	[521]	[88,29]	-4	hSpCas9	negative selection	1817859
109743689	109743712	6	-	26627737	HCT116	viability after 6 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.1929322742856825	[1155]	[335,136]	1	hSpCas9	negative selection	1817860
109763950	109763973	6	+	26627737	HCT116	viability after 6 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.3386378611885422	[328]	[105,4]	-2	hSpCas9	negative selection	1817861
109766812	109766835	6	+	26627737	HCT116	viability after 6 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	1.386610939239902	[1300]	[1032,259]	7	hSpCas9	negative selection	1817862
109786428	109786451	6	+	26627737	HCT116	viability after 6 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.1848200588898783	[1379]	[535,86]	1	hSpCas9	negative selection	1817863
109716525	109716548	6	+	26627737	HCT116	viability after 8 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.7022569031911698	[397]	[191,128,84]	-7	hSpCas9	negative selection	1900173
109743109	109743132	6	+	26627737	HCT116	viability after 8 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.0028723731418845433	[336]	[132,232,188]	0	hSpCas9	negative selection	1900174
109743689	109743712	6	-	26627737	HCT116	viability after 8 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.264539916628182	[518]	[256,422,348]	3	hSpCas9	negative selection	1900175
109763950	109763973	6	+	26627737	HCT116	viability after 8 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.8555500689118594	[194]	[22,39,25]	-9	hSpCas9	negative selection	1900176
109766812	109766835	6	+	26627737	HCT116	viability after 8 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.5382568673055901	[421]	[269,250,488]	5	hSpCas9	negative selection	1900177
109786428	109786451	6	+	26627737	HCT116	viability after 8 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.3726442457858631	[766]	[348,246,382]	-4	hSpCas9	negative selection	1900178
109716525	109716548	6	+	26627737	HCT116	viability after 9 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.21870957056390422	[910]	[160,246]	-1	hSpCas9	negative selection	1982488
109743109	109743132	6	+	26627737	HCT116	viability after 9 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.9395155109724926	[521]	[8,122]	-6	hSpCas9	negative selection	1982489
109743689	109743712	6	-	26627737	HCT116	viability after 9 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	-1.0041624590338945	[1155]	[235,88]	-6	hSpCas9	negative selection	1982490
109763950	109763973	6	+	26627737	HCT116	viability after 9 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-2.3295288916573886	[328]	[31,5]	-9	hSpCas9	negative selection	1982491
109766812	109766835	6	+	26627737	HCT116	viability after 9 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.29849843059140113	[1300]	[753,168]	2	hSpCas9	negative selection	1982492
109786428	109786451	6	+	26627737	HCT116	viability after 9 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.8054111038428993	[1379]	[383,73]	-5	hSpCas9	negative selection	1982493
109716525	109716548	6	+	26627737	HCT116	viability after 12 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.007107442412151	[397]	[65,122,126]	-8	hSpCas9	negative selection	2064803
109743109	109743132	6	+	26627737	HCT116	viability after 12 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.15017646850795427	[336]	[114,171,195]	-1	hSpCas9	negative selection	2064804
109743689	109743712	6	-	26627737	HCT116	viability after 12 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.2428361356991301	[518]	[422,345,190]	2	hSpCas9	negative selection	2064805
109763950	109763973	6	+	26627737	HCT116	viability after 12 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.6728736864381886	[194]	[2,32,62]	-9	hSpCas9	negative selection	2064806
109766812	109766835	6	+	26627737	HCT116	viability after 12 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.021368700532748364	[421]	[131,248,302]	0	hSpCas9	negative selection	2064807
109786428	109786451	6	+	26627737	HCT116	viability after 12 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.828774120975578	[766]	[256,219,200]	-7	hSpCas9	negative selection	2064808
109716525	109716548	6	+	26627737	HCT116	viability after 15 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.5446679171407571	[397]	[97,24,113]	-8	hSpCas9	negative selection	2147118
109743109	109743132	6	+	26627737	HCT116	viability after 15 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.4539164178530311	[336]	[167,106,151]	-5	hSpCas9	negative selection	2147119
109743689	109743712	6	-	26627737	HCT116	viability after 15 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	-0.054238195026261704	[518]	[407,271,196]	0	hSpCas9	negative selection	2147120
109763950	109763973	6	+	26627737	HCT116	viability after 15 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-3.8613437111509086	[194]	[14,0,7]	-9	hSpCas9	negative selection	2147121
109766812	109766835	6	+	26627737	HCT116	viability after 15 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.23200866581055085	[421]	[115,280,210]	-2	hSpCas9	negative selection	2147122
109786428	109786451	6	+	26627737	HCT116	viability after 15 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-1.5558018147218164	[766]	[232,109,116]	-8	hSpCas9	negative selection	2147123
109716525	109716548	6	+	26627737	HCT116	viability after 18 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.9408078109968927	[397]	[53,42,53]	-9	hSpCas9	negative selection	2229433
109743109	109743132	6	+	26627737	HCT116	viability after 18 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.8919573123902769	[336]	[85,108,65]	-7	hSpCas9	negative selection	2229434
109743689	109743712	6	-	26627737	HCT116	viability after 18 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.6222313750840073	[518]	[477,336,344]	5	hSpCas9	negative selection	2229435
109763950	109763973	6	+	26627737	HCT116	viability after 18 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.3365407890104963	[194]	[62,0,50]	-8	hSpCas9	negative selection	2229436
109766812	109766835	6	+	26627737	HCT116	viability after 18 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.018211736692951508	[421]	[106,114,396]	0	hSpCas9	negative selection	2229437
109786428	109786451	6	+	26627737	HCT116	viability after 18 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-1.9952255294834607	[766]	[64,138,70]	-9	hSpCas9	negative selection	2229438
109691381	109691404	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACGAGCCTCCGGACCGCCCCAGG	FIG4	ENSG00000112367	-0.4579286311479125	[150,48]	[13,16]	-2	dCas9-VP64	positive selection	2402269
109691356	109691379	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCGGCGAGAAAACCCCTCAGG	FIG4	ENSG00000112367	0.009260482979320583	[46,25]	[8,6]	0	dCas9-VP64	positive selection	2402270
109691314	109691337	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTAATGGGTGTTGTTCCTGG	FIG4	ENSG00000112367	0.4695138274914832	[54,21]	[18,2]	2	dCas9-VP64	positive selection	2402271
109818288	109818311	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATTGCTTGAACCCAGGAGG	FIG4	ENSG00000112367	0.059142044687262585	[6,100]	[1,23]	0	dCas9-VP64	positive selection	2407405
109692814	109692837	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTAGCTACTTGGGAGGCTGGGG	FIG4	ENSG00000112367	2.3677236295083457	[37,27]	[69,1]	7	dCas9-VP64	positive selection	2412091
109795145	109795168	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCGCCCAGGCGGG	FIG4	ENSG00000112367	-0.2966468943215429	[82,22]	[4,12]	-1	dCas9-VP64	positive selection	2413456
109691381	109691404	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACGAGCCTCCGGACCGCCCCAGG	FIG4	ENSG00000112367	0.15510428184871938	[110,60]	[33,28]	1	dCas9-VP64	positive selection	2497524
109691356	109691379	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCGGCGAGAAAACCCCTCAGG	FIG4	ENSG00000112367	0.008786574127430238	[74,163]	[19,55]	0	dCas9-VP64	positive selection	2497525
109691314	109691337	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTAATGGGTGTTGTTCCTGG	FIG4	ENSG00000112367	3.0372093350623475	[82,19]	[14,256]	9	dCas9-VP64	positive selection	2497526
109818288	109818311	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATTGCTTGAACCCAGGAGG	FIG4	ENSG00000112367	0.5790361197083687	[35,47]	[19,19]	4	dCas9-VP64	positive selection	2502660
109692814	109692837	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTAGCTACTTGGGAGGCTGGGG	FIG4	ENSG00000112367	0.1906181633953845	[24,86]	[25,14]	1	dCas9-VP64	positive selection	2507346
109795145	109795168	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCGCCCAGGCGGG	FIG4	ENSG00000112367	1.7427299536741634	[67,144]	[186,48]	8	dCas9-VP64	positive selection	2508711
109716527	109716550	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.052864948026399794	[3,2]	[2,2]	0	hSpCas9	positive selection	2988705
109760355	109760378	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	-0.35115890871788524	[3,4]	[2,2]	-5	hSpCas9	positive selection	2988706
109762166	109762189	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	0.06148732141955793	[5,5]	[4,5]	1	hSpCas9	positive selection	2988707
109716483	109716506	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	0.3300097645654926	[5,5]	[5,5]	7	hSpCas9	positive selection	2988708
109716527	109716550	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.24031841456500402	[3,3]	[3,1]	4	hSpCas9	positive selection	3056563
109760355	109760378	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	0.007986584402066316	[3,3]	[3,1]	0	hSpCas9	positive selection	3056564
109762166	109762189	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	-0.10653243913501009	[5,5]	[5,2]	-1	hSpCas9	positive selection	3056565
109716483	109716506	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	0.2542922103598525	[5,5]	[5,3]	4	hSpCas9	positive selection	3056566
109735189	109735212		+	24336571	A375	resistance to PLX after 7 days	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.24527012903562984	[22,19]	[17,17]	-7	hSpCas9	positive selection	3114812
109732666	109732689		+	24336571	A375	resistance to PLX after 7 days	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	0.10182665892913856	[18,16]	[17,19]	3	hSpCas9	positive selection	3114813
109732640	109732663		+	24336571	A375	resistance to PLX after 7 days	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.20252774269292736	[13,13]	[12,9]	-6	hSpCas9	positive selection	3114814
109735189	109735212		+	24336571	A375	resistance to PLX after 14 days	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.02174184846232413	[13,18]	[6,7]	0	hSpCas9	positive selection	3172605
109732666	109732689		+	24336571	A375	resistance to PLX after 14 days	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	-0.5894204646948655	[20,19]	[5,5]	-7	hSpCas9	positive selection	3172606
109732640	109732663		+	24336571	A375	resistance to PLX after 14 days	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.613692117264002	[12,16]	[3,3]	-7	hSpCas9	positive selection	3172607
109735189	109735212		+	24336571	A375	viability after 7 days	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.07233827430479012	[20]	[22,19]	1	hSpCas9	negative selection	3230398
109732666	109732689		+	24336571	A375	viability after 7 days	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	0.10477825109712696	[17]	[18,16]	1	hSpCas9	negative selection	3230399
109732640	109732663		+	24336571	A375	viability after 7 days	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.39008769356572726	[18]	[13,13]	-5	hSpCas9	negative selection	3230400
109735189	109735212		+	24336571	A375	viability after 14 days	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.2797137704297752	[20]	[13,18]	-3	hSpCas9	negative selection	3288191
109732666	109732689		+	24336571	A375	viability after 14 days	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	0.30819340921277977	[17]	[20,19]	4	hSpCas9	negative selection	3288192
109732640	109732663		+	24336571	A375	viability after 14 days	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.23516388993718434	[18]	[12,16]	-3	hSpCas9	negative selection	3288193
109735189	109735212	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	3.8627654434150407	[12,7]	[0,0]	9	hSpCas9	positive selection	3350107
109735243	109735266	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	-0.2504166180458872	[180,182]	[0,0]	-1	hSpCas9	positive selection	3350108
109762118	109762141	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	2.372287851819507	[36,21]	[0,0]	8	hSpCas9	positive selection	3350109
109732664	109732687	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	14.941198080068439	[7,7]	[1644,1644]	9	hSpCas9	positive selection	3369323
109762170	109762193	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3369324
109732640	109732663	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3369325
109716527	109716550	6	-	26780180	HT29	viability (Avana library 4 designs)	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	2.31395822317187	[]	[]	8	hSpCas9	negative selection	3425615
109760355	109760378	6	-	26780180	HT29	viability (Avana library 4 designs)	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	-0.361099635657856	[]	[]	-5	hSpCas9	negative selection	3425616
109762166	109762189	6	-	26780180	HT29	viability (Avana library 4 designs)	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	0.544825443101779	[]	[]	2	hSpCas9	negative selection	3425617
109716483	109716506	6	-	26780180	HT29	viability (Avana library 4 designs)	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	0.308473923714232	[]	[]	1	hSpCas9	negative selection	3425618
109716483	109716506	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	-16.4312629611349	[]	[]	-9	hSpCas9	negative selection	3507830
109716527	109716550	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	2.82971623109167	[]	[]	4	hSpCas9	negative selection	3507831
109760355	109760378	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	0.181588761441942	[]	[]	0	hSpCas9	negative selection	3507832
109762166	109762189	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	-3.51072900365331	[]	[]	-4	hSpCas9	negative selection	3507833
109735277	109735300	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAATTACACAAGGTGGAAGCGG	FIG4	ENSG00000112367	-1.46754293839438	[]	[]	-2	hSpCas9	negative selection	3507834
109727244	109727267	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTCATCCTGATGAAGCTAGG	FIG4	ENSG00000112367	-1.93693379512141	[]	[]	-2	hSpCas9	negative selection	3507835
109716483	109716506	6	-	26780180	A375	viability (Avana lentiGuide)	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	3.94447015137311	[]	[]	4	hSpCas9	negative selection	3616489
109716527	109716550	6	-	26780180	A375	viability (Avana lentiGuide)	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	3.58407958107765	[]	[]	3	hSpCas9	negative selection	3616490
109760355	109760378	6	-	26780180	A375	viability (Avana lentiGuide)	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	7.47411228889781	[]	[]	6	hSpCas9	negative selection	3616491
109762166	109762189	6	-	26780180	A375	viability (Avana lentiGuide)	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	8.0652257433718	[]	[]	6	hSpCas9	negative selection	3616492
109735277	109735300	6	+	26780180	A375	viability (Avana lentiGuide)	TTAATTACACAAGGTGGAAGCGG	FIG4	ENSG00000112367	-0.199742658273786	[]	[]	0	hSpCas9	negative selection	3616493
109727244	109727267	6	+	26780180	A375	viability (Avana lentiGuide)	TTACTCATCCTGATGAAGCTAGG	FIG4	ENSG00000112367	1.50180506881559	[]	[]	1	hSpCas9	negative selection	3616494
109716483	109716506	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	-0.8211168452476341	[9]	[5,4]	-8	hSpCas9	positive selection	3725148
109716527	109716550	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.12721068819451956	[4]	[5,4]	3	hSpCas9	positive selection	3725149
109760355	109760378	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	-0.0737931632724671	[5]	[5,4]	-1	hSpCas9	positive selection	3725150
109762166	109762189	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	-0.25442672393811616	[6]	[5,4]	-4	hSpCas9	positive selection	3725151
109735277	109735300	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAATTACACAAGGTGGAAGCGG	FIG4	ENSG00000112367	-0.23420412442592392	[6]	[5,5]	-4	hSpCas9	positive selection	3725152
109727244	109727267	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTCATCCTGATGAAGCTAGG	FIG4	ENSG00000112367	-0.28725578611097724	[6]	[4,4]	-4	hSpCas9	positive selection	3725153
109716483	109716506	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTATTTCCAAGATCCAAGCGG	FIG4	ENSG00000112367	0.1017510397428662	[7]	[6,6]	2	hSpCas9	positive selection	3833755
109716527	109716550	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.03579574571799979	[4]	[4,3]	0	hSpCas9	positive selection	3833756
109760355	109760378	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATACTTGGCCATGTCCCAGGG	FIG4	ENSG00000112367	-0.6207787728935887	[5]	[3,1]	-7	hSpCas9	positive selection	3833757
109762166	109762189	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCTACAGTAAGAATCAGGGCGG	FIG4	ENSG00000112367	0.13248946219242091	[7]	[7,6]	3	hSpCas9	positive selection	3833758
109735277	109735300	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAATTACACAAGGTGGAAGCGG	FIG4	ENSG00000112367	0.07901577866902407	[5]	[4,4]	1	hSpCas9	positive selection	3833759
109727244	109727267	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTCATCCTGATGAAGCTAGG	FIG4	ENSG00000112367	0.03932153944488517	[6]	[6,4]	0	hSpCas9	positive selection	3833760
109762170	109762193	6	-	26780180	A375	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.814548816433365	[]	[]	3	hSpCas9	negative selection	3941041
109762118	109762141	6	+	26780180	A375	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.25644212187858	[]	[]	0	hSpCas9	negative selection	3941042
109735243	109735266	6	-	26780180	A375	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.262972511807546	[]	[]	0	hSpCas9	negative selection	3941043
109735189	109735212	6	+	26780180	A375	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.779260548986001	[]	[]	3	hSpCas9	negative selection	3941044
109732664	109732687	6	-	26780180	A375	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.380119727382396	[]	[]	0	hSpCas9	negative selection	3941045
109732640	109732663	6	+	26780180	A375	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	1.18443899656805	[]	[]	6	hSpCas9	negative selection	3941046
109762170	109762193	6	-	26780180	HT29	viability (GeCKOv2 library)	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	1.24118786842606	[]	[]	6	hSpCas9	negative selection	4049007
109762118	109762141	6	+	26780180	HT29	viability (GeCKOv2 library)	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.686265096076629	[]	[]	2	hSpCas9	negative selection	4049008
109735243	109735266	6	-	26780180	HT29	viability (GeCKOv2 library)	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.672244364699813	[]	[]	2	hSpCas9	negative selection	4049009
109735189	109735212	6	+	26780180	HT29	viability (GeCKOv2 library)	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.884380687736168	[]	[]	4	hSpCas9	negative selection	4049010
109732664	109732687	6	-	26780180	HT29	viability (GeCKOv2 library)	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.911580171205526	[]	[]	4	hSpCas9	negative selection	4049011
109732640	109732663	6	+	26780180	HT29	viability (GeCKOv2 library)	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	1.28624146643088	[]	[]	6	hSpCas9	negative selection	4049012
109735189	109735212	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.10875800322328445	[4]	[2,2]	-3	hSpCas9	positive selection	4137860
109732666	109732689	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	-0.04355978631484689	[4]	[2,2]	-1	hSpCas9	positive selection	4137861
109732640	109732663	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.07627916159366682	[3]	[2,1]	2	hSpCas9	positive selection	4137862
109735189	109735212	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.24388561560906874	[4]	[0,1,3,0]	-4	hSpCas9	positive selection	4201882
109732666	109732689	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCTAGCAATTTTTACTTTAGG	FIG4	ENSG00000112367	-0.35984118099596735	[4]	[0,2,2,0]	-5	hSpCas9	positive selection	4201883
109732640	109732663	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.1010591411213774	[4]	[0,3,2,0]	-1	hSpCas9	positive selection	4201884
109735189	109735212	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.1963413422405913	[0]	[0,0]	-4	hSpCas9	positive selection	4271198
109735243	109735266	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.15508557740301737	[3]	[3,2]	3	hSpCas9	positive selection	4271199
109762118	109762141	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.18316628641253074	[1]	[1,0]	3	hSpCas9	positive selection	4271200
109732664	109732687	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.12153057475745177	[0]	[1,0]	2	hSpCas9	positive selection	4335463
109762170	109762193	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.31041193338030293	[1]	[1,0]	-6	hSpCas9	positive selection	4335464
109732640	109732663	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.27893473694687104	[2]	[2,1]	5	hSpCas9	positive selection	4335465
109716527	109716549	6	-	27760321	OCIAML3	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.09139067233832512	[560,444]	[313,435]	-1	hSpCas9	negative selection	4401322
109735190	109735212	6	+	27760321	OCIAML3	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.47573035410828735	[849,786]	[832,964]	5	hSpCas9	negative selection	4401323
109738395	109738417	6	+	27760321	OCIAML3	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-0.13901486197959104	[573,521]	[345,444]	-1	hSpCas9	negative selection	4401324
109741464	109741486	6	-	27760321	OCIAML3	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	0.3370769214291691	[58,47]	[62,38]	4	hSpCas9	negative selection	4401325
109741510	109741532	6	+	27760321	OCIAML3	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.10460043350447235	[127,116]	[82,128]	1	hSpCas9	negative selection	4401326
109716527	109716549	6	-	27760321	OCIAML2	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.0008105266445407044	[560,444]	[379,435]	0	hSpCas9	negative selection	4484785
109735190	109735212	6	+	27760321	OCIAML2	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.313955383669992	[849,786]	[729,945]	4	hSpCas9	negative selection	4484786
109738395	109738417	6	+	27760321	OCIAML2	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-0.8312943101581545	[573,521]	[248,248]	-7	hSpCas9	negative selection	4484787
109741464	109741486	6	-	27760321	OCIAML2	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	0.7847714175196936	[58,47]	[68,80]	9	hSpCas9	negative selection	4484788
109741510	109741532	6	+	27760321	OCIAML2	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.7062424536549059	[127,116]	[133,197]	8	hSpCas9	negative selection	4484789
109716527	109716549	6	-	27760321	MV411	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	1.4890493068767325	[560,444]	[1144,596]	9	hSpCas9	negative selection	4568248
109735190	109735212	6	+	27760321	MV411	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.7491900284146776	[849,786]	[300,351]	-5	hSpCas9	negative selection	4568249
109738395	109738417	6	+	27760321	MV411	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	0.0752389149212862	[573,521]	[564,103]	0	hSpCas9	negative selection	4568250
109741464	109741486	6	-	27760321	MV411	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-4.455961404650048	[58,47]	[1,0]	-9	hSpCas9	negative selection	4568251
109741510	109741532	6	+	27760321	MV411	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	1.4814150674613413	[127,116]	[257,176]	9	hSpCas9	negative selection	4568252
109716527	109716549	6	-	27760321	HL60	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.27841799874313033	[560,444]	[292,382]	-3	hSpCas9	negative selection	4651711
109735190	109735212	6	+	27760321	HL60	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.05934538806338896	[849,786]	[589,809]	0	hSpCas9	negative selection	4651712
109738395	109738417	6	+	27760321	HL60	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.0632268593570167	[573,521]	[150,280]	-8	hSpCas9	negative selection	4651713
109741464	109741486	6	-	27760321	HL60	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-1.024808970967876	[58,47]	[16,25]	-7	hSpCas9	negative selection	4651714
109741510	109741532	6	+	27760321	HL60	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	2.019821443442816	[127,116]	[426,382]	9	hSpCas9	negative selection	4651715
109716527	109716549	6	-	27760321	HT1080	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	1.4059103709186485	[444,346]	[533,290]	7	hSpCas9	negative selection	4735174
109735190	109735212	6	+	27760321	HT1080	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.29151953755384086	[786,613]	[373,305]	1	hSpCas9	negative selection	4735175
109738395	109738417	6	+	27760321	HT1080	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	0.5557243258230307	[521,407]	[299,241]	3	hSpCas9	negative selection	4735176
109741464	109741486	6	-	27760321	HT1080	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-4.099720918204987	[47,37]	[0,0]	-8	hSpCas9	negative selection	4735177
109741510	109741532	6	+	27760321	HT1080	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.5218128107104736	[116,91]	[44,75]	2	hSpCas9	negative selection	4735178
109716527	109716549	6	-	27760321	HT29	viability after 7 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.5240165993896523	[444,346]	[811,802,595]	7	hSpCas9	negative selection	4818637
109735190	109735212	6	+	27760321	HT29	viability after 7 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.14861640370714402	[786,613]	[927,1134,922]	2	hSpCas9	negative selection	4818638
109738395	109738417	6	+	27760321	HT29	viability after 7 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.2009381258288447	[521,407]	[440,241,126]	-9	hSpCas9	negative selection	4818639
109741464	109741486	6	-	27760321	HT29	viability after 7 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-0.7021497297939079	[47,37]	[48,48,6]	-7	hSpCas9	negative selection	4818640
109741510	109741532	6	+	27760321	HT29	viability after 7 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.3216829361239526	[116,91]	[299,131,92]	5	hSpCas9	negative selection	4818641
109716527	109716549	6	-	27760321	HT29	viability after 25 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.18591961905251347	[444,346]	[279,429,500]	-2	hSpCas9	negative selection	4902100
109735190	109735212	6	+	27760321	HT29	viability after 25 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.5636243886818115	[786,613]	[288,774,579]	-5	hSpCas9	negative selection	4902101
109738395	109738417	6	+	27760321	HT29	viability after 25 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.8745991060852756	[521,407]	[143,176,109]	-8	hSpCas9	negative selection	4902102
109741464	109741486	6	-	27760321	HT29	viability after 25 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-1.0023107179448858	[47,37]	[63,0,3]	-6	hSpCas9	negative selection	4902103
109741510	109741532	6	+	27760321	HT29	viability after 25 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	-0.10168009160243119	[116,91]	[30,152,159]	-1	hSpCas9	negative selection	4902104
109716527	109716549	6	-	27760321	HT29	viability after 22 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.13306415484415252	[444,346]	[298,590,364]	-1	hSpCas9	negative selection	4985563
109735190	109735212	6	+	27760321	HT29	viability after 22 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.4341101188678068	[786,613]	[776,550,463]	-4	hSpCas9	negative selection	4985564
109738395	109738417	6	+	27760321	HT29	viability after 22 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.356707486282951	[521,407]	[179,299,149]	-7	hSpCas9	negative selection	4985565
109741464	109741486	6	-	27760321	HT29	viability after 22 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-1.5862831699378268	[47,37]	[37,7,2]	-7	hSpCas9	negative selection	4985566
109741510	109741532	6	+	27760321	HT29	viability after 22 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	-0.21900850829209273	[116,91]	[31,120,160]	-2	hSpCas9	negative selection	4985567
109716527	109716549	6	-	27760321	HT29	viability after 19 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.5134315232341026	[444,346]	[525,252,198]	-4	hSpCas9	negative selection	5069026
109735190	109735212	6	+	27760321	HT29	viability after 19 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.9720874083433209	[786,613]	[611,273,361]	-6	hSpCas9	negative selection	5069027
109738395	109738417	6	+	27760321	HT29	viability after 19 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.4891035137720452	[521,407]	[149,354,63]	-7	hSpCas9	negative selection	5069028
109741464	109741486	6	-	27760321	HT29	viability after 19 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	1.2922652204843328	[47,37]	[1,7,330]	9	hSpCas9	negative selection	5069029
109741510	109741532	6	+	27760321	HT29	viability after 19 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.3595198873620762	[116,91]	[65,151,229]	3	hSpCas9	negative selection	5069030
109716527	109716549	6	-	27760321	HT29	viability after 16 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.1717487108543805	[444,346]	[400,680,400]	1	hSpCas9	negative selection	5152489
109735190	109735212	6	+	27760321	HT29	viability after 16 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-1.0764598217433154	[786,613]	[541,329,259]	-7	hSpCas9	negative selection	5152490
109738395	109738417	6	+	27760321	HT29	viability after 16 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.9442039125568045	[521,407]	[115,202,82]	-8	hSpCas9	negative selection	5152491
109741464	109741486	6	-	27760321	HT29	viability after 16 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-0.6351461278316255	[47,37]	[86,3,7]	-5	hSpCas9	negative selection	5152492
109741510	109741532	6	+	27760321	HT29	viability after 16 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.21656023879167385	[116,91]	[181,176,51]	2	hSpCas9	negative selection	5152493
109716527	109716549	6	-	27760321	HT29	viability after 13 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.025428412918881454	[444,346]	[403,399,590]	0	hSpCas9	negative selection	5235952
109735190	109735212	6	+	27760321	HT29	viability after 13 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.08725905260154243	[786,613]	[1085,750,474]	-1	hSpCas9	negative selection	5235953
109738395	109738417	6	+	27760321	HT29	viability after 13 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-1.0712505762100506	[521,407]	[99,369,297]	-7	hSpCas9	negative selection	5235954
109741464	109741486	6	-	27760321	HT29	viability after 13 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	0.12538768061767014	[47,37]	[92,27,42]	1	hSpCas9	negative selection	5235955
109741510	109741532	6	+	27760321	HT29	viability after 13 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	1.0117570527199808	[116,91]	[106,314,307]	9	hSpCas9	negative selection	5235956
109716527	109716549	6	-	27760321	HT29	viability after 10 days	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.18528563064405432	[444,346]	[331,797,562]	2	hSpCas9	negative selection	5319415
109735190	109735212	6	+	27760321	HT29	viability after 10 days	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.33672059797890697	[786,613]	[894,591,589]	-4	hSpCas9	negative selection	5319416
109738395	109738417	6	+	27760321	HT29	viability after 10 days	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-0.7777903486380942	[521,407]	[303,455,260]	-7	hSpCas9	negative selection	5319417
109741464	109741486	6	-	27760321	HT29	viability after 10 days	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	-0.9905622562889396	[47,37]	[25,44,10]	-8	hSpCas9	negative selection	5319418
109741510	109741532	6	+	27760321	HT29	viability after 10 days	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	-1.0069164566242856	[116,91]	[66,86,41]	-8	hSpCas9	negative selection	5319419
109716527	109716549	6	-	27760321	MOLM13	viability	ACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.568415239763935	[560,444]	[79,283]	-4	hSpCas9	negative selection	5402878
109735190	109735212	6	+	27760321	MOLM13	viability	ACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.23168318857107528	[849,786]	[786,333]	1	hSpCas9	negative selection	5402879
109738395	109738417	6	+	27760321	MOLM13	viability	AAGTACTGTGCATCGTGACTGG	FIG4	ENSG00000112367	-0.8151806756181873	[573,521]	[274,90]	-5	hSpCas9	negative selection	5402880
109741464	109741486	6	-	27760321	MOLM13	viability	CTATTAGAGTGACATACACTGG	FIG4	ENSG00000112367	0.5554293781004027	[58,47]	[75,16]	4	hSpCas9	negative selection	5402881
109741510	109741532	6	+	27760321	MOLM13	viability	GCACCCGTTTTCTTAAAAGAGG	FIG4	ENSG00000112367	0.01817330903699732	[127,116]	[130,17]	0	hSpCas9	negative selection	5402882
109691497	109691520	6	+	27661255	K562	viability	GAGCTGTGAGTACCCCCTCGCGG	FIG4	ENSG00000112367	-0.14780610204535188	[1101,1154]	[880,754]	-5	dCas9-KRAB	negative selection	5480310
109691555	109691578	6	+	27661255	K562	viability	GGTGTGGGGCCGTAGGACAGAGG	FIG4	ENSG00000112367	0.11334788601891288	[912,1201]	[979,848]	4	dCas9-KRAB	negative selection	5480311
109691652	109691675	6	-	27661255	K562	viability	GGCGCCCAGGCACAGCTCAAGGG	FIG4	ENSG00000112367	0.25091275681740466	[302,382]	[335,314]	8	dCas9-KRAB	negative selection	5480312
109735189	109735212	6	+	27260156	BXPC3	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.20747318853050345	[65]	[52,76,118,71]	4	hSpCas9	negative selection	5543658
109735243	109735266	6	-	27260156	BXPC3	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.4449255038479219	[640]	[857,759,1071,978]	8	hSpCas9	negative selection	5543659
109762118	109762141	6	+	27260156	BXPC3	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.10245882734426148	[96]	[125,73,103,133]	2	hSpCas9	negative selection	5543660
109732664	109732687	6	-	27260156	BXPC3	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.12130852099253264	[58]	[49,72,29,74]	-3	hSpCas9	negative selection	5607923
109762170	109762193	6	-	27260156	BXPC3	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.04572419462854915	[184]	[150,202,240,152]	-1	hSpCas9	negative selection	5607924
109732640	109732663	6	+	27260156	BXPC3	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.20439064301137866	[214]	[171,244,124,240]	-5	hSpCas9	negative selection	5607925
109735189	109735212	6	+	27260156	A673	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.19890931981273452	[65]	[95,109,51,106]	5	hSpCas9	negative selection	5664909
109735243	109735266	6	-	27260156	A673	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.2745100346808083	[640]	[798,858,971,1086]	6	hSpCas9	negative selection	5664910
109762118	109762141	6	+	27260156	A673	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.3461094885316316	[96]	[144,190,132,119]	7	hSpCas9	negative selection	5664911
109732664	109732687	6	-	27260156	A673	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.3370933506467009	[58]	[69,41,45,68]	-7	hSpCas9	negative selection	5729174
109762170	109762193	6	-	27260156	A673	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.03661238455653715	[184]	[254,277,114,267]	0	hSpCas9	negative selection	5729175
109732640	109732663	6	+	27260156	A673	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.06451228591679614	[214]	[367,235,181,213]	-2	hSpCas9	negative selection	5729176
109735189	109735212	6	+	27260156	A375	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.09048901547461075	[65]	[63,138,82,18]	-1	hSpCas9	negative selection	5786160
109735243	109735266	6	-	27260156	A375	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.6945799760429967	[640]	[1126,1266,1436,1038]	8	hSpCas9	negative selection	5786161
109762118	109762141	6	+	27260156	A375	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	-0.32948148018926027	[96]	[107,79,52,114]	-5	hSpCas9	negative selection	5786162
109732664	109732687	6	-	27260156	A375	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.5307511796804643	[58]	[149,145,39,71]	7	hSpCas9	negative selection	5850425
109762170	109762193	6	-	27260156	A375	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.6108621417644384	[184]	[430,264,474,159]	8	hSpCas9	negative selection	5850426
109732640	109732663	6	+	27260156	A375	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.12320951116803203	[214]	[238,349,209,300]	1	hSpCas9	negative selection	5850427
109735189	109735212	6	+	27260156	COLO741	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.2896677188158221	[65]	[110,155,46]	6	hSpCas9	negative selection	5907411
109735243	109735266	6	-	27260156	COLO741	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.38685605770940273	[640]	[1134,1168,922]	7	hSpCas9	negative selection	5907412
109762118	109762141	6	+	27260156	COLO741	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.19840951406236806	[96]	[140,153,131]	4	hSpCas9	negative selection	5907413
109732664	109732687	6	-	27260156	COLO741	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.49134787052728157	[58]	[105,137,75]	8	hSpCas9	negative selection	5971676
109762170	109762193	6	-	27260156	COLO741	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	1.6771158975333538	[184]	[302,1551,400]	9	hSpCas9	negative selection	5971677
109732640	109732663	6	+	27260156	COLO741	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.2633919930155022	[214]	[204,192,281]	-5	hSpCas9	negative selection	5971678
109735189	109735212	6	+	27260156	CAL120	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.2410273683116415	[65]	[60,66,78]	-4	hSpCas9	negative selection	6028662
109735243	109735266	6	-	27260156	CAL120	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.40448948226482145	[640]	[1161,1137,885]	6	hSpCas9	negative selection	6028663
109762118	109762141	6	+	27260156	CAL120	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.40501596439201615	[96]	[148,180,147]	6	hSpCas9	negative selection	6028664
109732664	109732687	6	-	27260156	CAL120	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.5604416786835982	[58]	[24,36,82]	-7	hSpCas9	negative selection	6092927
109762170	109762193	6	-	27260156	CAL120	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.48986639938865717	[184]	[495,247,252]	7	hSpCas9	negative selection	6092928
109732640	109732663	6	+	27260156	CAL120	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.20962589434947732	[214]	[505,331,122]	3	hSpCas9	negative selection	6092929
109735189	109735212	6	+	27260156	CADOES1	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.12719518265588947	[65]	[71,98,19,32]	-2	hSpCas9	negative selection	6149913
109735243	109735266	6	-	27260156	CADOES1	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.4226155523056743	[640]	[884,779,758,770]	7	hSpCas9	negative selection	6149914
109762118	109762141	6	+	27260156	CADOES1	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.8250598869318553	[96]	[174,145,189,126]	9	hSpCas9	negative selection	6149915
109732664	109732687	6	-	27260156	CADOES1	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.5584362161516245	[58]	[44,29,36,36]	-7	hSpCas9	negative selection	6214178
109762170	109762193	6	-	27260156	CADOES1	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.14732958553546727	[184]	[90,89,244,196]	-3	hSpCas9	negative selection	6214179
109732640	109732663	6	+	27260156	CADOES1	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.19062175105414048	[214]	[192,260,255,201]	3	hSpCas9	negative selection	6214180
109735189	109735212	6	+	27260156	EWS502	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.19057598176375734	[65]	[57,73,111,77]	3	hSpCas9	negative selection	6271164
109735243	109735266	6	-	27260156	EWS502	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.49628095860382265	[640]	[834,1010,1162,823]	8	hSpCas9	negative selection	6271165
109762118	109762141	6	+	27260156	EWS502	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.4667260816171255	[96]	[124,205,175,53]	7	hSpCas9	negative selection	6271166
109732664	109732687	6	-	27260156	EWS502	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.11096632944634299	[58]	[146,18,31,20]	-2	hSpCas9	negative selection	6335429
109762170	109762193	6	-	27260156	EWS502	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.0929082847499485	[184]	[233,180,199,107]	-2	hSpCas9	negative selection	6335430
109732640	109732663	6	+	27260156	EWS502	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.45063103139773397	[214]	[455,186,270,316]	7	hSpCas9	negative selection	6335431
109735189	109735212	6	+	27260156	EW8	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.27325499602920855	[65]	[28,79,22,46]	-5	hSpCas9	negative selection	6392415
109735243	109735266	6	-	27260156	EW8	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.44431091682174745	[640]	[681,650,748,732]	7	hSpCas9	negative selection	6392416
109762118	109762141	6	+	27260156	EW8	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.5701088376442975	[96]	[150,140,125,50]	8	hSpCas9	negative selection	6392417
109732664	109732687	6	-	27260156	EW8	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.8647429320307176	[58]	[22,52,18,10]	-9	hSpCas9	negative selection	6456680
109762170	109762193	6	-	27260156	EW8	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.03310778995007535	[184]	[172,136,124,184]	0	hSpCas9	negative selection	6456681
109732640	109732663	6	+	27260156	EW8	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.12209811699796158	[214]	[184,270,153,153]	2	hSpCas9	negative selection	6456682
109735189	109735212	6	+	27260156	CORL105	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.6349751496939651	[65]	[45,55,44,50]	-8	hSpCas9	negative selection	6513666
109735243	109735266	6	-	27260156	CORL105	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.245530452461093	[640]	[832,754,1013,975]	4	hSpCas9	negative selection	6513667
109762118	109762141	6	+	27260156	CORL105	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.1595304863548801	[96]	[71,165,166,105]	3	hSpCas9	negative selection	6513668
109732664	109732687	6	-	27260156	CORL105	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.06050810749375568	[58]	[132,60,36,53]	1	hSpCas9	negative selection	6577931
109762170	109762193	6	-	27260156	CORL105	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.2760452610258912	[184]	[149,199,222,147]	-5	hSpCas9	negative selection	6577932
109732640	109732663	6	+	27260156	CORL105	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.21980717381874193	[214]	[259,149,258,204]	-4	hSpCas9	negative selection	6577933
109735189	109735212	6	+	27260156	HS294T	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.42223383308670126	[65]	[10,10,21,35]	-5	hSpCas9	negative selection	6634917
109735243	109735266	6	-	27260156	HS294T	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.7356783189755247	[640]	[340,261,538,540]	8	hSpCas9	negative selection	6634918
109762118	109762141	6	+	27260156	HS294T	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.13401378895915883	[96]	[19,36,31,84]	1	hSpCas9	negative selection	6634919
109732664	109732687	6	-	27260156	HS294T	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.5095875339570375	[58]	[9,9,22,22]	-6	hSpCas9	negative selection	6699182
109762170	109762193	6	-	27260156	HS294T	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.07708021300335433	[184]	[47,66,89,67]	-1	hSpCas9	negative selection	6699183
109732640	109732663	6	+	27260156	HS294T	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.17815273721095393	[214]	[69,76,171,52]	2	hSpCas9	negative selection	6699184
109735189	109735212	6	+	27260156	HCC44	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.2158068747098687	[65]	[19,74,133,34]	-4	hSpCas9	negative selection	6756168
109735243	109735266	6	-	27260156	HCC44	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.25413902593175447	[640]	[963,677,1083,800]	4	hSpCas9	negative selection	6756169
109762118	109762141	6	+	27260156	HCC44	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.46288189556906256	[96]	[151,124,218,123]	7	hSpCas9	negative selection	6756170
109732664	109732687	6	-	27260156	HCC44	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.05122868663334579	[58]	[73,100,67,29]	0	hSpCas9	negative selection	6820433
109762170	109762193	6	-	27260156	HCC44	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.4136446285403257	[184]	[189,282,416,238]	6	hSpCas9	negative selection	6820434
109732640	109732663	6	+	27260156	HCC44	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.5386986188587919	[214]	[150,492,423,316]	8	hSpCas9	negative selection	6820435
109735189	109735212	6	+	27260156	G402	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.03195922655435712	[65]	[80,151,19,79]	0	hSpCas9	negative selection	6877419
109735243	109735266	6	-	27260156	G402	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.6249064122996009	[640]	[1196,1131,1335,1151]	7	hSpCas9	negative selection	6877420
109762118	109762141	6	+	27260156	G402	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	1.4593688239872793	[96]	[146,346,199,569]	9	hSpCas9	negative selection	6877421
109732664	109732687	6	-	27260156	G402	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.3258053063660995	[58]	[18,116,66,25]	-4	hSpCas9	negative selection	6941684
109762170	109762193	6	-	27260156	G402	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.02428600550856963	[184]	[534,170,168,89]	0	hSpCas9	negative selection	6941685
109732640	109732663	6	+	27260156	G402	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.6951470927288508	[214]	[333,496,359,493]	8	hSpCas9	negative selection	6941686
109735189	109735212	6	+	27260156	L33	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.06556495942082252	[65]	[98,25,33,58]	1	hSpCas9	negative selection	6998670
109735243	109735266	6	-	27260156	L33	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.47439299241002447	[640]	[852,396,451,1019]	8	hSpCas9	negative selection	6998671
109762118	109762141	6	+	27260156	L33	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.26389270688234223	[96]	[83,22,145,94]	5	hSpCas9	negative selection	6998672
109732664	109732687	6	-	27260156	L33	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.2144524554101972	[58]	[56,34,32,78]	4	hSpCas9	negative selection	7062935
109762170	109762193	6	-	27260156	L33	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.18470583621005288	[184]	[209,59,131,273]	4	hSpCas9	negative selection	7062936
109732640	109732663	6	+	27260156	L33	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.403566325767472	[214]	[255,133,230,188]	8	hSpCas9	negative selection	7062937
109735189	109735212	6	+	27260156	K562	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.8987378827031627	[65]	[8,37,16,56]	-7	hSpCas9	negative selection	7119921
109735243	109735266	6	-	27260156	K562	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.5345051793869267	[640]	[1204,862,664,616]	6	hSpCas9	negative selection	7119922
109762118	109762141	6	+	27260156	K562	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.19095698028303065	[96]	[201,46,131,25]	2	hSpCas9	negative selection	7119923
109732664	109732687	6	-	27260156	K562	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.21937718784823845	[58]	[76,47,7,48]	-3	hSpCas9	negative selection	7184186
109762170	109762193	6	-	27260156	K562	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.4758062715431851	[184]	[134,133,93,503]	6	hSpCas9	negative selection	7184187
109732640	109732663	6	+	27260156	K562	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.052057521841788024	[214]	[236,188,252,122]	0	hSpCas9	negative selection	7184188
109735189	109735212	6	+	27260156	HT29	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.01699462721542533	[65]	[109,64,56,84]	0	hSpCas9	negative selection	7241172
109735243	109735266	6	-	27260156	HT29	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.43358905289949407	[640]	[1211,1010,947,1040]	8	hSpCas9	negative selection	7241173
109762118	109762141	6	+	27260156	HT29	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.22327965539964012	[96]	[105,125,174,138]	4	hSpCas9	negative selection	7241174
109732664	109732687	6	-	27260156	HT29	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.009224627379232242	[58]	[95,37,97,56]	0	hSpCas9	negative selection	7305437
109762170	109762193	6	-	27260156	HT29	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.00992493917238968	[184]	[246,298,220,153]	0	hSpCas9	negative selection	7305438
109732640	109732663	6	+	27260156	HT29	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.24004159865288643	[214]	[434,221,217,353]	5	hSpCas9	negative selection	7305439
109735189	109735212	6	+	27260156	MHHES1	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.5003225515199947	[65]	[4,55,75,63]	-7	hSpCas9	negative selection	7362423
109735243	109735266	6	-	27260156	MHHES1	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.525878276117701	[640]	[1102,1414,990,740]	8	hSpCas9	negative selection	7362424
109762118	109762141	6	+	27260156	MHHES1	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	-0.010818855171476738	[96]	[80,139,60,140]	0	hSpCas9	negative selection	7362425
109732664	109732687	6	-	27260156	MHHES1	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.7746989627858056	[58]	[66,20,8,54]	-8	hSpCas9	negative selection	7426688
109762170	109762193	6	-	27260156	MHHES1	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.33457346972825164	[184]	[349,234,238,234]	6	hSpCas9	negative selection	7426689
109732640	109732663	6	+	27260156	MHHES1	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.3242119396116586	[214]	[495,374,264,138]	6	hSpCas9	negative selection	7426690
109735189	109735212	6	+	27260156	MEWO	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.03964858775129931	[65]	[71,71,47]	0	hSpCas9	negative selection	7483674
109735243	109735266	6	-	27260156	MEWO	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.229003001610745	[640]	[726,721,663]	5	hSpCas9	negative selection	7483675
109762118	109762141	6	+	27260156	MEWO	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.8785113052793192	[96]	[179,173,148]	9	hSpCas9	negative selection	7483676
109732664	109732687	6	-	27260156	MEWO	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.27966881544893285	[58]	[42,29,62]	-6	hSpCas9	negative selection	7547939
109762170	109762193	6	-	27260156	MEWO	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.3394116601914259	[184]	[174,86,155]	-6	hSpCas9	negative selection	7547940
109732640	109732663	6	+	27260156	MEWO	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.1153639862101008	[214]	[148,167,232]	-3	hSpCas9	negative selection	7547941
109735189	109735212	6	+	27260156	LNCAPCLONEFGC	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.15560675356365294	[65]	[73,44,74,23]	-2	hSpCas9	negative selection	7604925
109735243	109735266	6	-	27260156	LNCAPCLONEFGC	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.376072956255379	[640]	[638,753,874,765]	6	hSpCas9	negative selection	7604926
109762118	109762141	6	+	27260156	LNCAPCLONEFGC	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.8147428125843856	[96]	[69,235,124,178]	9	hSpCas9	negative selection	7604927
109732664	109732687	6	-	27260156	LNCAPCLONEFGC	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.055737752801359175	[58]	[29,64,88,42]	0	hSpCas9	negative selection	7669190
109762170	109762193	6	-	27260156	LNCAPCLONEFGC	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.17086112637647877	[184]	[160,136,306,170]	2	hSpCas9	negative selection	7669191
109732640	109732663	6	+	27260156	LNCAPCLONEFGC	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.12285412129335449	[214]	[160,259,272,160]	2	hSpCas9	negative selection	7669192
109735189	109735212	6	+	27260156	PANC0327	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.20533492431227618	[65]	[61,127,4,66]	3	hSpCas9	negative selection	7726176
109735243	109735266	6	-	27260156	PANC0327	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.24682656829371846	[640]	[786,610,715,605]	3	hSpCas9	negative selection	7726177
109762118	109762141	6	+	27260156	PANC0327	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.8660108723614912	[96]	[206,87,101,243]	9	hSpCas9	negative selection	7726178
109732664	109732687	6	-	27260156	PANC0327	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-2.0742229254655005	[58]	[10,9,23,4]	-9	hSpCas9	negative selection	7790441
109762170	109762193	6	-	27260156	PANC0327	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.003968863921457677	[184]	[171,122,135,233]	0	hSpCas9	negative selection	7790442
109732640	109732663	6	+	27260156	PANC0327	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.3381467315605641	[214]	[322,129,370,162]	5	hSpCas9	negative selection	7790443
109735189	109735212	6	+	27260156	NCIH2009	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.38690261590935693	[65]	[111,110,136]	5	hSpCas9	negative selection	7847427
109735243	109735266	6	-	27260156	NCIH2009	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.6891450293858863	[640]	[1486,1385,1465]	8	hSpCas9	negative selection	7847428
109762118	109762141	6	+	27260156	NCIH2009	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	-0.2233487225698747	[96]	[127,83,138]	-3	hSpCas9	negative selection	7847429
109732664	109732687	6	-	27260156	NCIH2009	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.16508166136353486	[58]	[78,101,39]	-2	hSpCas9	negative selection	7911692
109762170	109762193	6	-	27260156	NCIH2009	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.04719758587943246	[184]	[223,242,277]	0	hSpCas9	negative selection	7911693
109732640	109732663	6	+	27260156	NCIH2009	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.4388932291655938	[214]	[439,317,470]	6	hSpCas9	negative selection	7911694
109735189	109735212	6	+	27260156	NCIH1373	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.014342635937976578	[65]	[66,81,102,10]	0	hSpCas9	negative selection	7968678
109735243	109735266	6	-	27260156	NCIH1373	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	1.1096446743948831	[640]	[2934,906,1003,433]	9	hSpCas9	negative selection	7968679
109762118	109762141	6	+	27260156	NCIH1373	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.22278302064540156	[96]	[246,103,73,26]	2	hSpCas9	negative selection	7968680
109732664	109732687	6	-	27260156	NCIH1373	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.30602957669640407	[58]	[16,171,97,3]	3	hSpCas9	negative selection	8032943
109762170	109762193	6	-	27260156	NCIH1373	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.17432835856077644	[184]	[351,102,86,60]	-2	hSpCas9	negative selection	8032944
109732640	109732663	6	+	27260156	NCIH1373	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.24172003059126035	[214]	[651,77,214,71]	2	hSpCas9	negative selection	8032945
109735189	109735212	6	+	27260156	PATU8902	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.909334973835219	[65]	[122,5,22,48]	-7	hSpCas9	negative selection	8089929
109735243	109735266	6	-	27260156	PATU8902	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.8368047561108811	[640]	[1603,971,1928,1794]	8	hSpCas9	negative selection	8089930
109762118	109762141	6	+	27260156	PATU8902	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.6626384003590107	[96]	[193,243,244,155]	7	hSpCas9	negative selection	8089931
109732664	109732687	6	-	27260156	PATU8902	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	1.7957917347686787	[58]	[263,816,58,28]	9	hSpCas9	negative selection	8154194
109762170	109762193	6	-	27260156	PATU8902	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.1879448984058405	[184]	[158,272,495,178]	2	hSpCas9	negative selection	8154195
109732640	109732663	6	+	27260156	PATU8902	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.1148737960798254	[214]	[281,197,349,475]	1	hSpCas9	negative selection	8154196
109735189	109735212	6	+	27260156	PANC1	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.2940810276286232	[65]	[46,143,22,76]	5	hSpCas9	negative selection	8211180
109735243	109735266	6	-	27260156	PANC1	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.38343916342506984	[640]	[585,1220,521,647]	6	hSpCas9	negative selection	8211181
109762118	109762141	6	+	27260156	PANC1	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.783559003578687	[96]	[105,89,190,169]	9	hSpCas9	negative selection	8211182
109732664	109732687	6	-	27260156	PANC1	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.7233415252226378	[58]	[31,93,94,110]	9	hSpCas9	negative selection	8275445
109762170	109762193	6	-	27260156	PANC1	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.03808954101370032	[184]	[166,190,108,155]	0	hSpCas9	negative selection	8275446
109732640	109732663	6	+	27260156	PANC1	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.49576914441711883	[214]	[249,285,235,268]	7	hSpCas9	negative selection	8275447
109735189	109735212	6	+	27260156	PANC0813	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.14807664417312028	[65]	[47,65,113,50]	-2	hSpCas9	negative selection	8332431
109735243	109735266	6	-	27260156	PANC0813	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.6246442865726116	[640]	[938,1298,1609,795]	8	hSpCas9	negative selection	8332432
109762118	109762141	6	+	27260156	PANC0813	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.037882467730796954	[96]	[68,62,235,96]	0	hSpCas9	negative selection	8332433
109732664	109732687	6	-	27260156	PANC0813	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.13318320669774542	[58]	[93,86,23,50]	-2	hSpCas9	negative selection	8396696
109762170	109762193	6	-	27260156	PANC0813	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.30219036246651276	[184]	[277,490,119,186]	5	hSpCas9	negative selection	8396697
109732640	109732663	6	+	27260156	PANC0813	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.39876031992247074	[214]	[198,351,394,370]	6	hSpCas9	negative selection	8396698
109735189	109735212	6	+	27260156	RDES	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.0006227892395123114	[65]	[73,68,50,112]	0	hSpCas9	negative selection	8453682
109735243	109735266	6	-	27260156	RDES	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.37393192822751525	[640]	[725,883,1118,1157]	6	hSpCas9	negative selection	8453683
109762118	109762141	6	+	27260156	RDES	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.10394594270807378	[96]	[121,84,91,188]	1	hSpCas9	negative selection	8453684
109732664	109732687	6	-	27260156	RDES	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.34258768367027814	[58]	[81,63,130,65]	5	hSpCas9	negative selection	8517947
109762170	109762193	6	-	27260156	RDES	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.2552793391623964	[184]	[224,215,254,333]	4	hSpCas9	negative selection	8517948
109732640	109732663	6	+	27260156	RDES	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.22973952923164853	[214]	[281,189,331,371]	4	hSpCas9	negative selection	8517949
109735189	109735212	6	+	27260156	PC3	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.19716590994013572	[65]	[82,65,94,48]	4	hSpCas9	negative selection	8574933
109735243	109735266	6	-	27260156	PC3	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.10011175920474341	[640]	[441,807,937,678]	2	hSpCas9	negative selection	8574934
109762118	109762141	6	+	27260156	PC3	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	-0.09530523376248867	[96]	[91,56,220,27]	-2	hSpCas9	negative selection	8574935
109732664	109732687	6	-	27260156	PC3	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-1.1280223637353224	[58]	[13,29,22,42]	-9	hSpCas9	negative selection	8639198
109762170	109762193	6	-	27260156	PC3	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.111320840509334	[184]	[110,193,280,266]	2	hSpCas9	negative selection	8639199
109732640	109732663	6	+	27260156	PC3	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.48462358937308847	[214]	[200,357,242,386]	8	hSpCas9	negative selection	8639200
109735189	109735212	6	+	27260156	PATU8988T	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-1.6755566215667321	[65]	[1,13,32,30]	-9	hSpCas9	negative selection	8696184
109735243	109735266	6	-	27260156	PATU8988T	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.45951670913673187	[640]	[1024,895,824,648]	7	hSpCas9	negative selection	8696185
109762118	109762141	6	+	27260156	PATU8988T	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.8466768950566728	[96]	[183,181,90,223]	9	hSpCas9	negative selection	8696186
109732664	109732687	6	-	27260156	PATU8988T	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.9665773012472747	[58]	[211,66,5,161]	9	hSpCas9	negative selection	8760449
109762170	109762193	6	-	27260156	PATU8988T	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.5047544898471386	[184]	[77,129,29,279]	-7	hSpCas9	negative selection	8760450
109732640	109732663	6	+	27260156	PATU8988T	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.27373103060197734	[214]	[198,140,186,155]	-4	hSpCas9	negative selection	8760451
109735189	109735212	6	+	27260156	T47D	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.0980534191546587	[65]	[98,76,88,63]	2	hSpCas9	negative selection	8817435
109735243	109735266	6	-	27260156	T47D	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.2794634356528673	[640]	[919,889,840,978]	6	hSpCas9	negative selection	8817436
109762118	109762141	6	+	27260156	T47D	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.2940793326679798	[96]	[128,154,146,120]	6	hSpCas9	negative selection	8817437
109732664	109732687	6	-	27260156	T47D	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.0515975259024577	[58]	[70,29,50,138]	1	hSpCas9	negative selection	8881700
109762170	109762193	6	-	27260156	T47D	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.32391411350356414	[184]	[256,215,309,300]	7	hSpCas9	negative selection	8881701
109732640	109732663	6	+	27260156	T47D	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.24849622045271813	[214]	[285,318,333,246]	5	hSpCas9	negative selection	8881702
109735189	109735212	6	+	27260156	SU8686	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.7800775075839073	[65]	[133,96,72,148]	9	hSpCas9	negative selection	8938686
109735243	109735266	6	-	27260156	SU8686	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.44364515162571166	[640]	[943,765,767,994]	7	hSpCas9	negative selection	8938687
109762118	109762141	6	+	27260156	SU8686	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.16197753273279725	[96]	[70,85,132,154]	2	hSpCas9	negative selection	8938688
109732664	109732687	6	-	27260156	SU8686	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.09876367182082335	[58]	[46,67,34,68]	-2	hSpCas9	negative selection	9002951
109762170	109762193	6	-	27260156	SU8686	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.4884621482339436	[184]	[214,240,329,248]	7	hSpCas9	negative selection	9002952
109732640	109732663	6	+	27260156	SU8686	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.03554576570334689	[214]	[239,245,175,199]	0	hSpCas9	negative selection	9002953
109735189	109735212	6	+	27260156	SKES1	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.34394677704956456	[65]	[134,74,25,101]	7	hSpCas9	negative selection	9059937
109735243	109735266	6	-	27260156	SKES1	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.24498594680120594	[640]	[802,685,883,657]	5	hSpCas9	negative selection	9059938
109762118	109762141	6	+	27260156	SKES1	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.4763411825824311	[96]	[214,110,178,49]	8	hSpCas9	negative selection	9059939
109732664	109732687	6	-	27260156	SKES1	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	-0.6663207007309349	[58]	[66,23,35,24]	-9	hSpCas9	negative selection	9124202
109762170	109762193	6	-	27260156	SKES1	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.07040064965301895	[184]	[242,126,138,255]	1	hSpCas9	negative selection	9124203
109732640	109732663	6	+	27260156	SKES1	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.19398557169290687	[214]	[101,280,223,144]	-4	hSpCas9	negative selection	9124204
109735189	109735212	6	+	27260156	TOV112D	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.22633238175865555	[65]	[134,18,37,31]	-4	hSpCas9	negative selection	9181188
109735243	109735266	6	-	27260156	TOV112D	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.1329715905504692	[640]	[474,1029,713,657]	2	hSpCas9	negative selection	9181189
109762118	109762141	6	+	27260156	TOV112D	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.003428060162896429	[96]	[131,95,104,59]	0	hSpCas9	negative selection	9181190
109732664	109732687	6	-	27260156	TOV112D	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.08077948751726893	[58]	[20,99,49,83]	1	hSpCas9	negative selection	9245453
109762170	109762193	6	-	27260156	TOV112D	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.07733821422365295	[184]	[130,249,133,200]	-1	hSpCas9	negative selection	9245454
109732640	109732663	6	+	27260156	TOV112D	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.20331631847082465	[214]	[270,172,326,204]	4	hSpCas9	negative selection	9245455
109735189	109735212	6	+	27260156	TC71	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	-0.05320508084684006	[65]	[43,77,30,124]	-1	hSpCas9	negative selection	9302439
109735243	109735266	6	-	27260156	TC71	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.1453300144314526	[640]	[708,785,615,945]	3	hSpCas9	negative selection	9302440
109762118	109762141	6	+	27260156	TC71	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.41637967518936003	[96]	[106,168,117,163]	8	hSpCas9	negative selection	9302441
109732664	109732687	6	-	27260156	TC71	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.08232286697744806	[58]	[51,73,63,78]	2	hSpCas9	negative selection	9366704
109762170	109762193	6	-	27260156	TC71	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	0.14975836678644305	[184]	[236,125,265,250]	4	hSpCas9	negative selection	9366705
109732640	109732663	6	+	27260156	TC71	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	0.2568287182636305	[214]	[252,268,313,263]	6	hSpCas9	negative selection	9366706
109735189	109735212	6	+	27260156	TC32	viability	CACTGTCTTGCGAATGCCCCTGG	FIG4	ENSG00000112367	0.5780026032428647	[65]	[50,46,134,166]	8	hSpCas9	negative selection	9423690
109735243	109735266	6	-	27260156	TC32	viability	CAAAGATGTCAAAGCTCTCTTGG	FIG4	ENSG00000112367	0.4574252533770398	[640]	[679,735,996,932]	7	hSpCas9	negative selection	9423691
109762118	109762141	6	+	27260156	TC32	viability	AAATGTGATTGCAGAAAGTGTGG	FIG4	ENSG00000112367	0.28018385126254586	[96]	[87,87,144,133]	5	hSpCas9	negative selection	9423692
109732664	109732687	6	-	27260156	TC32	viability	TAAAGTAAAAATTGCTAGATAGG	FIG4	ENSG00000112367	0.06508650105592073	[58]	[100,4,115,29]	1	hSpCas9	negative selection	9487955
109762170	109762193	6	-	27260156	TC32	viability	AAAATGCTACAGTAAGAATCAGG	FIG4	ENSG00000112367	-0.054470429335006454	[184]	[183,29,260,257]	-1	hSpCas9	negative selection	9487956
109732640	109732663	6	+	27260156	TC32	viability	TCTACGAATATTTCAAAATGTGG	FIG4	ENSG00000112367	-0.01276644611620359	[214]	[157,107,386,210]	0	hSpCas9	negative selection	9487957
109716525	109716548	6	+	27869803	HPAFII	viability after 27 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.302563380917851	[327]	[112,33,NaN]	-7	hSpCas9	negative selection	9593182
109743109	109743132	6	+	27869803	HPAFII	viability after 27 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-2.490331894823327	[273]	[35,16,NaN]	-8	hSpCas9	negative selection	9593183
109743689	109743712	6	-	27869803	HPAFII	viability after 27 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.4245287811585239	[574]	[276,512,NaN]	3	hSpCas9	negative selection	9593184
109763950	109763973	6	+	27869803	HPAFII	viability after 27 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.6913293782687904	[128]	[14,25,NaN]	-8	hSpCas9	negative selection	9593185
109766812	109766835	6	+	27869803	HPAFII	viability after 27 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.8951614668749004	[556]	[61,236,NaN]	-6	hSpCas9	negative selection	9593186
109786428	109786451	6	+	27869803	HPAFII	viability after 27 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.39246755734765737	[487]	[267,134,NaN]	-3	hSpCas9	negative selection	9593187
109716525	109716548	6	+	27869803	HPAFII	viability after 15 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.7243655548614195	[327]	[340,133,NaN]	-6	hSpCas9	negative selection	9675631
109743109	109743132	6	+	27869803	HPAFII	viability after 15 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.2644739781833081	[273]	[439,123,NaN]	-3	hSpCas9	negative selection	9675632
109743689	109743712	6	-	27869803	HPAFII	viability after 15 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.10430711602071452	[574]	[704,638,NaN]	1	hSpCas9	negative selection	9675633
109763950	109763973	6	+	27869803	HPAFII	viability after 15 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.9958937603767819	[128]	[79,62,NaN]	-7	hSpCas9	negative selection	9675634
109766812	109766835	6	+	27869803	HPAFII	viability after 15 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.8286836923598527	[556]	[349,328,NaN]	-7	hSpCas9	negative selection	9675635
109786428	109786451	6	+	27869803	HPAFII	viability after 15 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.16492978791907908	[487]	[756,287,NaN]	-2	hSpCas9	negative selection	9675636
109716525	109716548	6	+	27869803	ASPC1	viability after 36 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.0163945474977236	[610]	[149,102,74]	-7	hSpCas9	negative selection	9758080
109743109	109743132	6	+	27869803	ASPC1	viability after 36 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.8810266869420303	[589]	[499,398,274]	8	hSpCas9	negative selection	9758081
109743689	109743712	6	-	27869803	ASPC1	viability after 36 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.11594713660295375	[1128]	[645,445,253]	1	hSpCas9	negative selection	9758082
109763950	109763973	6	+	27869803	ASPC1	viability after 36 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-0.18587498942598968	[208]	[57,83,51]	-2	hSpCas9	negative selection	9758083
109766812	109766835	6	+	27869803	ASPC1	viability after 36 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	0.03297935908132499	[1085]	[376,405,376]	0	hSpCas9	negative selection	9758084
109786428	109786451	6	+	27869803	ASPC1	viability after 36 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	0.8392346924142364	[1005]	[700,681,527]	7	hSpCas9	negative selection	9758085
109716525	109716548	6	+	27869803	PATU8988S	viability after 35 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	0.5098727392476365	[629]	[490,230,NaN]	5	hSpCas9	negative selection	9840529
109743109	109743132	6	+	27869803	PATU8988S	viability after 35 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.2032282706463304	[468]	[194,132,NaN]	-2	hSpCas9	negative selection	9840530
109743689	109743712	6	-	27869803	PATU8988S	viability after 35 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	-0.21741151600718944	[1159]	[328,474,NaN]	-2	hSpCas9	negative selection	9840531
109763950	109763973	6	+	27869803	PATU8988S	viability after 35 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.2706829508095923	[206]	[57,10,NaN]	-8	hSpCas9	negative selection	9840532
109766812	109766835	6	+	27869803	PATU8988S	viability after 35 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.3113281868131241	[813]	[134,393,NaN]	-3	hSpCas9	negative selection	9840533
109786428	109786451	6	+	27869803	PATU8988S	viability after 35 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.15523673823087814	[970]	[427,273,NaN]	-2	hSpCas9	negative selection	9840534
109716525	109716548	6	+	27869803	PATU8988S	viability after 31 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-0.16715413758819933	[629]	[250,188,NaN]	-2	hSpCas9	negative selection	9922978
109743109	109743132	6	+	27869803	PATU8988S	viability after 31 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.06594588992260877	[468]	[182,211,NaN]	0	hSpCas9	negative selection	9922979
109743689	109743712	6	-	27869803	PATU8988S	viability after 31 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	-0.10492955057069009	[1159]	[309,582,NaN]	-1	hSpCas9	negative selection	9922980
109763950	109763973	6	+	27869803	PATU8988S	viability after 31 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.8586141113621109	[206]	[20,24,NaN]	-9	hSpCas9	negative selection	9922981
109766812	109766835	6	+	27869803	PATU8988S	viability after 31 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.42486642239338646	[813]	[144,364,NaN]	-5	hSpCas9	negative selection	9922982
109786428	109786451	6	+	27869803	PATU8988S	viability after 31 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.0873590556112902	[970]	[319,420,NaN]	-1	hSpCas9	negative selection	9922983
109716525	109716548	6	+	27869803	HPAFII	viability after 35 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.3464436324436841	[327]	[77,50,NaN]	-6	hSpCas9	negative selection	10005427
109743109	109743132	6	+	27869803	HPAFII	viability after 35 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-2.2262622243875563	[273]	[23,35,NaN]	-8	hSpCas9	negative selection	10005428
109743689	109743712	6	-	27869803	HPAFII	viability after 35 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.5454794907254457	[574]	[239,632,NaN]	3	hSpCas9	negative selection	10005429
109763950	109763973	6	+	27869803	HPAFII	viability after 35 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-3.2970282678847216	[128]	[0,12,NaN]	-8	hSpCas9	negative selection	10005430
109766812	109766835	6	+	27869803	HPAFII	viability after 35 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.5008445000201273	[556]	[36,381,NaN]	-3	hSpCas9	negative selection	10005431
109786428	109786451	6	+	27869803	HPAFII	viability after 35 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-0.39733947680589055	[487]	[275,87,NaN]	-2	hSpCas9	negative selection	10005432
109716525	109716548	6	+	27869803	HPAFII	viability after 31 days	ATCCTCGGGCTTATTTCGAGCGG	FIG4	ENSG00000112367	-1.4501158189080299	[327]	[97,33,NaN]	-7	hSpCas9	negative selection	10087876
109743109	109743132	6	+	27869803	HPAFII	viability after 31 days	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-2.6208046935105442	[273]	[24,24,NaN]	-8	hSpCas9	negative selection	10087877
109743689	109743712	6	-	27869803	HPAFII	viability after 31 days	AGGGCAGCCACATGTGCAAATGG	FIG4	ENSG00000112367	0.49893345960259516	[574]	[277,649,NaN]	3	hSpCas9	negative selection	10087878
109763950	109763973	6	+	27869803	HPAFII	viability after 31 days	GGAGGATGTGTGATTCCCACTGG	FIG4	ENSG00000112367	-1.7320726081143063	[128]	[5,38,NaN]	-7	hSpCas9	negative selection	10087879
109766812	109766835	6	+	27869803	HPAFII	viability after 31 days	CCTACAGAAAGATAGCACCATGG	FIG4	ENSG00000112367	-0.8406067348851693	[556]	[52,306,NaN]	-5	hSpCas9	negative selection	10087880
109786428	109786451	6	+	27869803	HPAFII	viability after 31 days	TGGCTATGACAAGCTCAGCACGG	FIG4	ENSG00000112367	-1.0218487869977773	[487]	[187,76,NaN]	-6	hSpCas9	negative selection	10087881
109765057	109765080	6	+	28162770	P31FUJ	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.5875793979394649	[251]	[444]	6	hSpCas9	negative selection	10157393
109743109	109743132	6	+	28162770	P31FUJ	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.8066669962522042	[258]	[86]	-8	hSpCas9	negative selection	10157394
109766771	109766794	6	-	28162770	P31FUJ	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	-0.9029320883982118	[470]	[295]	-6	hSpCas9	negative selection	10157395
109776957	109776980	6	+	28162770	P31FUJ	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.28526962430851416	[223]	[215]	-3	hSpCas9	negative selection	10157396
109791390	109791413	6	+	28162770	P31FUJ	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.8691115851357553	[285]	[183]	-6	hSpCas9	negative selection	10157397
109743714	109743737	6	+	28162770	P31FUJ	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.3689035601413537	[256]	[389]	4	hSpCas9	negative selection	10157398
109776984	109777007	6	-	28162770	P31FUJ	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-2.061690288021624	[269]	[75]	-8	hSpCas9	negative selection	10157399
109791550	109791573	6	+	28162770	P31FUJ	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.41292297296257935	[212]	[187]	-4	hSpCas9	negative selection	10157400
109716527	109716550	6	-	28162770	P31FUJ	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.38480529785942874	[29]	[26]	-3	hSpCas9	negative selection	10157401
109735205	109735228	6	-	28162770	P31FUJ	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.0004682706525869218	[603]	[709]	0	hSpCas9	negative selection	10157402
109765057	109765080	6	+	28162770	TF1	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10326759
109743109	109743132	6	+	28162770	TF1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10326760
109766771	109766794	6	-	28162770	TF1	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	NaN	[NaN]	[418]	1	hSpCas9	negative selection	10326761
109776957	109776980	6	+	28162770	TF1	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10326762
109791390	109791413	6	+	28162770	TF1	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10326763
109743714	109743737	6	+	28162770	TF1	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10326764
109776984	109777007	6	-	28162770	TF1	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10326765
109791550	109791573	6	+	28162770	TF1	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	NaN	[NaN]	[283]	1	hSpCas9	negative selection	10326766
109716527	109716550	6	-	28162770	TF1	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10326767
109735205	109735228	6	-	28162770	TF1	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	NaN	[NaN]	[399]	1	hSpCas9	negative selection	10326768
109765057	109765080	6	+	28162770	SKM1	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	1.1294544500199577	[67]	[262]	9	hSpCas9	negative selection	10496125
109743109	109743132	6	+	28162770	SKM1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.18108279132683397	[58]	[91]	-1	hSpCas9	negative selection	10496126
109766771	109766794	6	-	28162770	SKM1	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.06118463699524468	[134]	[248]	0	hSpCas9	negative selection	10496127
109776957	109776980	6	+	28162770	SKM1	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.6382897448496173	[80]	[91]	-5	hSpCas9	negative selection	10496128
109791390	109791413	6	+	28162770	SKM1	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.05261462616342194	[87]	[149]	0	hSpCas9	negative selection	10496129
109743714	109743737	6	+	28162770	SKM1	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.8330083002274074	[66]	[210]	7	hSpCas9	negative selection	10496130
109776984	109777007	6	-	28162770	SKM1	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.7480011165782285	[56]	[59]	-5	hSpCas9	negative selection	10496131
109791550	109791573	6	+	28162770	SKM1	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	1.0824206419957634	[38]	[145]	8	hSpCas9	negative selection	10496132
109716527	109716550	6	-	28162770	SKM1	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.44349007476827573	[9]	[12]	-4	hSpCas9	negative selection	10496133
109735205	109735228	6	-	28162770	SKM1	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.41344687613988895	[109]	[258]	4	hSpCas9	negative selection	10496134
109765057	109765080	6	+	28162770	SKM1	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	1.1294544500199577	[67]	[262]	9	hSpCas9	negative selection	10665491
109743109	109743132	6	+	28162770	SKM1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.18108279132683397	[58]	[91]	-1	hSpCas9	negative selection	10665492
109766771	109766794	6	-	28162770	SKM1	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.06118463699524468	[134]	[248]	0	hSpCas9	negative selection	10665493
109776957	109776980	6	+	28162770	SKM1	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.6382897448496173	[80]	[91]	-5	hSpCas9	negative selection	10665494
109791390	109791413	6	+	28162770	SKM1	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.05261462616342194	[87]	[149]	0	hSpCas9	negative selection	10665495
109743714	109743737	6	+	28162770	SKM1	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.8330083002274074	[66]	[210]	7	hSpCas9	negative selection	10665496
109776984	109777007	6	-	28162770	SKM1	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.7480011165782285	[56]	[59]	-5	hSpCas9	negative selection	10665497
109791550	109791573	6	+	28162770	SKM1	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	1.0824206419957634	[38]	[145]	8	hSpCas9	negative selection	10665498
109716527	109716550	6	-	28162770	SKM1	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.44349007476827573	[9]	[12]	-4	hSpCas9	negative selection	10665499
109735205	109735228	6	-	28162770	SKM1	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.41344687613988895	[109]	[258]	4	hSpCas9	negative selection	10665500
109765057	109765080	6	+	28162770	PL21	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	-0.058077775046697755	[298]	[124]	0	hSpCas9	negative selection	10834857
109743109	109743132	6	+	28162770	PL21	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.6873856562522673	[147]	[19]	-8	hSpCas9	negative selection	10834858
109766771	109766794	6	-	28162770	PL21	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	-0.13000898720301057	[615]	[244]	-1	hSpCas9	negative selection	10834859
109776957	109776980	6	+	28162770	PL21	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	0.40697059867502733	[252]	[145]	3	hSpCas9	negative selection	10834860
109791390	109791413	6	+	28162770	PL21	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.33552758997506227	[373]	[128]	-2	hSpCas9	negative selection	10834861
109743714	109743737	6	+	28162770	PL21	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	-0.23874462674389157	[243]	[89]	-2	hSpCas9	negative selection	10834862
109776984	109777007	6	-	28162770	PL21	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.42134876225694984	[199]	[64]	-3	hSpCas9	negative selection	10834863
109791550	109791573	6	+	28162770	PL21	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.40285680906209764	[160]	[52]	-3	hSpCas9	negative selection	10834864
109716527	109716550	6	-	28162770	PL21	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-1.4628253982331096	[18]	[2]	-7	hSpCas9	negative selection	10834865
109735205	109735228	6	-	28162770	PL21	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-0.8189187213263645	[380]	[93]	-5	hSpCas9	negative selection	10834866
109765057	109765080	6	+	28162770	P31FUJ	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.5875793979394649	[251]	[444]	6	hSpCas9	negative selection	11004223
109743109	109743132	6	+	28162770	P31FUJ	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.8066669962522042	[258]	[86]	-8	hSpCas9	negative selection	11004224
109766771	109766794	6	-	28162770	P31FUJ	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	-0.9029320883982118	[470]	[295]	-6	hSpCas9	negative selection	11004225
109776957	109776980	6	+	28162770	P31FUJ	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.28526962430851416	[223]	[215]	-3	hSpCas9	negative selection	11004226
109791390	109791413	6	+	28162770	P31FUJ	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.8691115851357553	[285]	[183]	-6	hSpCas9	negative selection	11004227
109743714	109743737	6	+	28162770	P31FUJ	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.3689035601413537	[256]	[389]	4	hSpCas9	negative selection	11004228
109776984	109777007	6	-	28162770	P31FUJ	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-2.061690288021624	[269]	[75]	-8	hSpCas9	negative selection	11004229
109791550	109791573	6	+	28162770	P31FUJ	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.41292297296257935	[212]	[187]	-4	hSpCas9	negative selection	11004230
109716527	109716550	6	-	28162770	P31FUJ	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-0.38480529785942874	[29]	[26]	-3	hSpCas9	negative selection	11004231
109735205	109735228	6	-	28162770	P31FUJ	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.0004682706525869218	[603]	[709]	0	hSpCas9	negative selection	11004232
109765057	109765080	6	+	28162770	OCIAML5	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.5969182603381844	[125]	[343]	5	hSpCas9	negative selection	11173589
109743109	109743132	6	+	28162770	OCIAML5	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.5452819622371766	[248]	[307]	-4	hSpCas9	negative selection	11173590
109766771	109766794	6	-	28162770	OCIAML5	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.29272621338049487	[340]	[753]	2	hSpCas9	negative selection	11173591
109776957	109776980	6	+	28162770	OCIAML5	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	0.30957181939335465	[96]	[216]	2	hSpCas9	negative selection	11173592
109791390	109791413	6	+	28162770	OCIAML5	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.40330317291872364	[172]	[412]	3	hSpCas9	negative selection	11173593
109743714	109743737	6	+	28162770	OCIAML5	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.5713344013494734	[128]	[345]	5	hSpCas9	negative selection	11173594
109776984	109777007	6	-	28162770	OCIAML5	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.6211121360241251	[143]	[168]	-4	hSpCas9	negative selection	11173595
109791550	109791573	6	+	28162770	OCIAML5	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	1.5703429170711993	[60]	[326]	9	hSpCas9	negative selection	11173596
109716527	109716550	6	-	28162770	OCIAML5	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.7724242940437969	[11]	[36]	6	hSpCas9	negative selection	11173597
109735205	109735228	6	-	28162770	OCIAML5	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.12480870364415275	[282]	[556]	1	hSpCas9	negative selection	11173598
109765057	109765080	6	+	28162770	EOL1	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.9070603448416937	[580]	[573]	7	hSpCas9	negative selection	11342955
109743109	109743132	6	+	28162770	EOL1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.4418797834836876	[213]	[82]	-3	hSpCas9	negative selection	11342956
109766771	109766794	6	-	28162770	EOL1	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.1611669906895168	[936]	[551]	1	hSpCas9	negative selection	11342957
109776957	109776980	6	+	28162770	EOL1	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.13378553874579263	[428]	[205]	-1	hSpCas9	negative selection	11342958
109791390	109791413	6	+	28162770	EOL1	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.2988389285060693	[789]	[511]	2	hSpCas9	negative selection	11342959
109743714	109743737	6	+	28162770	EOL1	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.31336775011306794	[471]	[308]	3	hSpCas9	negative selection	11342960
109776984	109777007	6	-	28162770	EOL1	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.4999500569573756	[305]	[56]	-7	hSpCas9	negative selection	11342961
109791550	109791573	6	+	28162770	EOL1	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	0.5907175876268805	[212]	[168]	5	hSpCas9	negative selection	11342962
109716527	109716550	6	-	28162770	EOL1	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-2.284905594058415	[36]	[3]	-8	hSpCas9	negative selection	11342963
109735205	109735228	6	-	28162770	EOL1	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.16166747865353537	[542]	[319]	1	hSpCas9	negative selection	11342964
109765057	109765080	6	+	28162770	MOLM13	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.7170848799133084	[418]	[497]	5	hSpCas9	negative selection	11512321
109743109	109743132	6	+	28162770	MOLM13	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.7279496207505526	[322]	[140]	-4	hSpCas9	negative selection	11512322
109766771	109766794	6	-	28162770	MOLM13	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.41803317510698124	[735]	[710]	3	hSpCas9	negative selection	11512323
109776957	109776980	6	+	28162770	MOLM13	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-1.1017251548431415	[373]	[125]	-5	hSpCas9	negative selection	11512324
109791390	109791413	6	+	28162770	MOLM13	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	-0.4100575083430792	[622]	[338]	-2	hSpCas9	negative selection	11512325
109743714	109743737	6	+	28162770	MOLM13	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	1.2439933696177434	[319]	[547]	8	hSpCas9	negative selection	11512326
109776984	109777007	6	-	28162770	MOLM13	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.0307128343733962	[307]	[108]	-5	hSpCas9	negative selection	11512327
109791550	109791573	6	+	28162770	MOLM13	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	0.4747757671298186	[208]	[209]	3	hSpCas9	negative selection	11512328
109716527	109716550	6	-	28162770	MOLM13	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.1741581784878683	[37]	[30]	1	hSpCas9	negative selection	11512329
109735205	109735228	6	-	28162770	MOLM13	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-1.1673463256578012	[729]	[234]	-6	hSpCas9	negative selection	11512330
109765057	109765080	6	+	28162770	HEL	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.14658559823705686	[377]	[267]	1	hSpCas9	negative selection	11681687
109743109	109743132	6	+	28162770	HEL	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-1.2928705807296883	[240]	[62]	-6	hSpCas9	negative selection	11681688
109766771	109766794	6	-	28162770	HEL	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.765325437468672	[653]	[711]	6	hSpCas9	negative selection	11681689
109776957	109776980	6	+	28162770	HEL	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	0.5792597751759567	[301]	[288]	5	hSpCas9	negative selection	11681690
109791390	109791413	6	+	28162770	HEL	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.543000689142972	[508]	[474]	4	hSpCas9	negative selection	11681691
109743714	109743737	6	+	28162770	HEL	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.5917876445536014	[316]	[305]	5	hSpCas9	negative selection	11681692
109776984	109777007	6	-	28162770	HEL	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.1104239896936505	[208]	[61]	-6	hSpCas9	negative selection	11681693
109791550	109791573	6	+	28162770	HEL	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	0.9765690159440109	[168]	[212]	8	hSpCas9	negative selection	11681694
109716527	109716550	6	-	28162770	HEL	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	0.10668593176014696	[28]	[19]	0	hSpCas9	negative selection	11681695
109735205	109735228	6	-	28162770	HEL	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.009141556028324338	[542]	[349]	0	hSpCas9	negative selection	11681696
109765057	109765080	6	+	28162770	MV411	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.8324000515039314	[237]	[356]	7	hSpCas9	negative selection	11851053
109743109	109743132	6	+	28162770	MV411	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.2968829654410348	[244]	[167]	-2	hSpCas9	negative selection	11851054
109766771	109766794	6	-	28162770	MV411	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.17965943634791537	[413]	[394]	1	hSpCas9	negative selection	11851055
109776957	109776980	6	+	28162770	MV411	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.10523406753569486	[248]	[194]	-1	hSpCas9	negative selection	11851056
109791390	109791413	6	+	28162770	MV411	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.4081733807704272	[279]	[312]	3	hSpCas9	negative selection	11851057
109743714	109743737	6	+	28162770	MV411	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.865014415758651	[276]	[424]	7	hSpCas9	negative selection	11851058
109776984	109777007	6	-	28162770	MV411	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.5941968535486354	[180]	[100]	-4	hSpCas9	negative selection	11851059
109791550	109791573	6	+	28162770	MV411	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-0.5095856957246844	[168]	[99]	-4	hSpCas9	negative selection	11851060
109716527	109716550	6	-	28162770	MV411	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-3.337524949938381	[23]	[1]	-9	hSpCas9	negative selection	11851061
109735205	109735228	6	-	28162770	MV411	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.019345841930339613	[464]	[396]	0	hSpCas9	negative selection	11851062
109765057	109765080	6	+	28162770	MONOMAC1	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	1.135345605464975	[219]	[553]	8	hSpCas9	negative selection	12020419
109743109	109743132	6	+	28162770	MONOMAC1	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.5932445616391091	[84]	[146]	6	hSpCas9	negative selection	12020420
109766771	109766794	6	-	28162770	MONOMAC1	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.4057369297780633	[321]	[488]	4	hSpCas9	negative selection	12020421
109776957	109776980	6	+	28162770	MONOMAC1	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.5256595945209244	[161]	[128]	-4	hSpCas9	negative selection	12020422
109791390	109791413	6	+	28162770	MONOMAC1	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.8029631529404462	[185]	[371]	7	hSpCas9	negative selection	12020423
109743714	109743737	6	+	28162770	MONOMAC1	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	1.1532055294222225	[110]	[282]	8	hSpCas9	negative selection	12020424
109776984	109777007	6	-	28162770	MONOMAC1	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.8368612828152281	[133]	[85]	-6	hSpCas9	negative selection	12020425
109791550	109791573	6	+	28162770	MONOMAC1	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	1.4122549830233433	[97]	[298]	9	hSpCas9	negative selection	12020426
109716527	109716550	6	-	28162770	MONOMAC1	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-1.1299226512010168	[20]	[10]	-7	hSpCas9	negative selection	12020427
109735205	109735228	6	-	28162770	MONOMAC1	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	-0.3819121899678374	[290]	[255]	-3	hSpCas9	negative selection	12020428
109765057	109765080	6	+	28162770	OCIAML2	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	0.8883290005901681	[49]	[512]	8	hSpCas9	negative selection	12189785
109743109	109743132	6	+	28162770	OCIAML2	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	0.6427116478337838	[25]	[224]	6	hSpCas9	negative selection	12189786
109766771	109766794	6	-	28162770	OCIAML2	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	-0.5805638522750017	[91]	[340]	-4	hSpCas9	negative selection	12189787
109776957	109776980	6	+	28162770	OCIAML2	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.30325150591019556	[62]	[282]	-2	hSpCas9	negative selection	12189788
109791390	109791413	6	+	28162770	OCIAML2	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.3089801063325386	[74]	[514]	3	hSpCas9	negative selection	12189789
109743714	109743737	6	+	28162770	OCIAML2	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.3650697225094046	[35]	[256]	3	hSpCas9	negative selection	12189790
109776984	109777007	6	-	28162770	OCIAML2	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-0.6810496049125332	[34]	[120]	-5	hSpCas9	negative selection	12189791
109791550	109791573	6	+	28162770	OCIAML2	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	0.25021610356076784	[26]	[177]	2	hSpCas9	negative selection	12189792
109716527	109716550	6	-	28162770	OCIAML2	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-1.4706298252421615	[6]	[13]	-7	hSpCas9	negative selection	12189793
109735205	109735228	6	-	28162770	OCIAML2	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.06414691831077812	[77]	[451]	0	hSpCas9	negative selection	12189794
109765057	109765080	6	+	28162770	OCIAML3	viability	CAACACAGCACAGTTTATGGTGG	FIG4	ENSG00000112367	1.051496402332044	[69]	[437]	8	hSpCas9	negative selection	12359151
109743109	109743132	6	+	28162770	OCIAML3	viability	GGGTGATGTTGCAAATGAAGTGG	FIG4	ENSG00000112367	-0.09520178335272145	[68]	[194]	0	hSpCas9	negative selection	12359152
109766771	109766794	6	-	28162770	OCIAML3	viability	GTTGAGAACCACCATACTGAAGG	FIG4	ENSG00000112367	0.1081383997673322	[129]	[422]	1	hSpCas9	negative selection	12359153
109776957	109776980	6	+	28162770	OCIAML3	viability	GGAGTTTTCCATCCCACTGAAGG	FIG4	ENSG00000112367	-0.6133729651910941	[74]	[147]	-5	hSpCas9	negative selection	12359154
109791390	109791413	6	+	28162770	OCIAML3	viability	GAGAAGAAGCTGTATTACAGCGG	FIG4	ENSG00000112367	0.09083522276591038	[92]	[298]	0	hSpCas9	negative selection	12359155
109743714	109743737	6	+	28162770	OCIAML3	viability	ACTTTGACCAGATGTTCCAGAGG	FIG4	ENSG00000112367	0.6283847810122849	[56]	[265]	6	hSpCas9	negative selection	12359156
109776984	109777007	6	-	28162770	OCIAML3	viability	GTTGGGAGCTCCCAGAGATGAGG	FIG4	ENSG00000112367	-1.1626683287162187	[65]	[88]	-7	hSpCas9	negative selection	12359157
109791550	109791573	6	+	28162770	OCIAML3	viability	AGACAGTGCCAAAGTGACCGAGG	FIG4	ENSG00000112367	-1.0090451396030071	[41]	[62]	-6	hSpCas9	negative selection	12359158
109716527	109716550	6	-	28162770	OCIAML3	viability	AACCGCTCGAAATAAGCCCGAGG	FIG4	ENSG00000112367	-4.9159357352115265	[9]	[0]	-9	hSpCas9	negative selection	12359159
109735205	109735228	6	-	28162770	OCIAML3	viability	TCTGACTTTAACATCTCCAGGGG	FIG4	ENSG00000112367	0.5283889910355634	[95]	[417]	5	hSpCas9	negative selection	12359160