Crispr
Gene Info
- Species: Human
(Homo sapiens)
- GeneID: 100132074
- Symbol: FOXO6
- Description: forkhead box O6
DataSource:
http://genomecrispr.dkfz.de/#!/results/FOXO6
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| Start |
The end |
chr |
strand |
pubmed |
cellline |
condition |
sequence |
symbol |
ensg |
log2fc |
rc_initial |
rc_final |
effect |
cas |
screentype |
index |
41362027 |
41362050 |
1 |
+ |
26627737 |
DLD1 |
viability |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.5232448860979442 |
[236] |
[100,148,75] |
5 |
hSpCas9 |
negative selection |
771412 |
41362172 |
41362195 |
1 |
+ |
26627737 |
DLD1 |
viability |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
1.2066946888534473 |
[181] |
[131,136,125] |
9 |
hSpCas9 |
negative selection |
771413 |
41381651 |
41381674 |
1 |
+ |
26627737 |
DLD1 |
viability |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.004962393888289673 |
[688] |
[188,269,194] |
0 |
hSpCas9 |
negative selection |
771414 |
41381652 |
41381675 |
1 |
+ |
26627737 |
DLD1 |
viability |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.03453645553588601 |
[486] |
[258,152,68] |
0 |
hSpCas9 |
negative selection |
771415 |
41381774 |
41381797 |
1 |
- |
26627737 |
DLD1 |
viability |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.7155162203069615 |
[660] |
[332,437,262] |
7 |
hSpCas9 |
negative selection |
771416 |
41382512 |
41382535 |
1 |
+ |
26627737 |
DLD1 |
viability |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
0.486196660219867 |
[339] |
[146,169,132] |
5 |
hSpCas9 |
negative selection |
771417 |
41362027 |
41362050 |
1 |
+ |
26627737 |
GBM cells |
viability after 5 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.11296022540260608 |
[121] |
[59,60] |
-2 |
hSpCas9 |
negative selection |
853727 |
41362172 |
41362195 |
1 |
+ |
26627737 |
GBM cells |
viability after 5 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.4357820874057967 |
[121] |
[89,86] |
6 |
hSpCas9 |
negative selection |
853728 |
41381651 |
41381674 |
1 |
+ |
26627737 |
GBM cells |
viability after 5 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.1805454995968097 |
[333] |
[190,214] |
3 |
hSpCas9 |
negative selection |
853729 |
41381652 |
41381675 |
1 |
+ |
26627737 |
GBM cells |
viability after 5 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.31395137416452923 |
[272] |
[179,183] |
5 |
hSpCas9 |
negative selection |
853730 |
41381774 |
41381797 |
1 |
- |
26627737 |
GBM cells |
viability after 5 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.6069869179292051 |
[231] |
[215,162] |
8 |
hSpCas9 |
negative selection |
853731 |
41382512 |
41382535 |
1 |
+ |
26627737 |
GBM cells |
viability after 5 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.5544517430522576 |
[177] |
[68,60] |
-7 |
hSpCas9 |
negative selection |
853732 |
41362027 |
41362050 |
1 |
+ |
26627737 |
GBM cells |
viability after 13 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.5248416665354401 |
[121] |
[61,32] |
-6 |
hSpCas9 |
negative selection |
936042 |
41362172 |
41362195 |
1 |
+ |
26627737 |
GBM cells |
viability after 13 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.5822217552444825 |
[121] |
[97,99] |
7 |
hSpCas9 |
negative selection |
936043 |
41381651 |
41381674 |
1 |
+ |
26627737 |
GBM cells |
viability after 13 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.17365232514850298 |
[333] |
[190,135] |
-2 |
hSpCas9 |
negative selection |
936044 |
41381652 |
41381675 |
1 |
+ |
26627737 |
GBM cells |
viability after 13 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.03265999962264263 |
[272] |
[145,155] |
0 |
hSpCas9 |
negative selection |
936045 |
41381774 |
41381797 |
1 |
- |
26627737 |
GBM cells |
viability after 13 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.4231800988002645 |
[231] |
[229,118] |
5 |
hSpCas9 |
negative selection |
936046 |
41382512 |
41382535 |
1 |
+ |
26627737 |
GBM cells |
viability after 13 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.8361912726185073 |
[177] |
[36,67] |
-7 |
hSpCas9 |
negative selection |
936047 |
41362027 |
41362050 |
1 |
+ |
26627737 |
GBM cells |
viability after 21 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.21536595937608594 |
[121] |
[54,58] |
-2 |
hSpCas9 |
negative selection |
1018357 |
41362172 |
41362195 |
1 |
+ |
26627737 |
GBM cells |
viability after 21 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
1.0094712668317922 |
[121] |
[134,131] |
8 |
hSpCas9 |
negative selection |
1018358 |
41381651 |
41381674 |
1 |
+ |
26627737 |
GBM cells |
viability after 21 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.2379210853135046 |
[333] |
[225,202] |
2 |
hSpCas9 |
negative selection |
1018359 |
41381652 |
41381675 |
1 |
+ |
26627737 |
GBM cells |
viability after 21 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
-0.09001216708001611 |
[272] |
[142,135] |
-1 |
hSpCas9 |
negative selection |
1018360 |
41381774 |
41381797 |
1 |
- |
26627737 |
GBM cells |
viability after 21 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.2921581870271665 |
[231] |
[169,139] |
3 |
hSpCas9 |
negative selection |
1018361 |
41382512 |
41382535 |
1 |
+ |
26627737 |
GBM cells |
viability after 21 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.7804371141578722 |
[177] |
[60,51] |
-6 |
hSpCas9 |
negative selection |
1018362 |
41362027 |
41362050 |
1 |
+ |
26627737 |
RPE1 |
viability after 9 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-1.1164740133909437 |
[896] |
[77,195] |
-7 |
hSpCas9 |
negative selection |
1100672 |
41362172 |
41362195 |
1 |
+ |
26627737 |
RPE1 |
viability after 9 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.12305910941401771 |
[569] |
[155,173] |
-1 |
hSpCas9 |
negative selection |
1100673 |
41381651 |
41381674 |
1 |
+ |
26627737 |
RPE1 |
viability after 9 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.7646846879099499 |
[1518] |
[199,382] |
-5 |
hSpCas9 |
negative selection |
1100674 |
41381652 |
41381675 |
1 |
+ |
26627737 |
RPE1 |
viability after 9 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.6493845524981738 |
[663] |
[260,409] |
4 |
hSpCas9 |
negative selection |
1100675 |
41381774 |
41381797 |
1 |
- |
26627737 |
RPE1 |
viability after 9 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.0642775545595131 |
[1148] |
[577,976] |
6 |
hSpCas9 |
negative selection |
1100676 |
41382512 |
41382535 |
1 |
+ |
26627737 |
RPE1 |
viability after 9 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-1.0052874692182987 |
[381] |
[35,89] |
-6 |
hSpCas9 |
negative selection |
1100677 |
41362027 |
41362050 |
1 |
+ |
26627737 |
RPE1 |
viability after 12 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-1.2830798410309199 |
[896] |
[82,115] |
-7 |
hSpCas9 |
negative selection |
1182987 |
41362172 |
41362195 |
1 |
+ |
26627737 |
RPE1 |
viability after 12 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.09941197733122992 |
[569] |
[140,144] |
0 |
hSpCas9 |
negative selection |
1182988 |
41381651 |
41381674 |
1 |
+ |
26627737 |
RPE1 |
viability after 12 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.08729562501367649 |
[1518] |
[286,486] |
0 |
hSpCas9 |
negative selection |
1182989 |
41381652 |
41381675 |
1 |
+ |
26627737 |
RPE1 |
viability after 12 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.8983444941325697 |
[663] |
[264,403] |
5 |
hSpCas9 |
negative selection |
1182990 |
41381774 |
41381797 |
1 |
- |
26627737 |
RPE1 |
viability after 12 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.1231855446586743 |
[1148] |
[601,746] |
6 |
hSpCas9 |
negative selection |
1182991 |
41382512 |
41382535 |
1 |
+ |
26627737 |
RPE1 |
viability after 12 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.6793865282213052 |
[381] |
[100,24] |
-5 |
hSpCas9 |
negative selection |
1182992 |
41362027 |
41362050 |
1 |
+ |
26627737 |
RPE1 |
viability after 15 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.6716866093670429 |
[896] |
[170,147] |
-4 |
hSpCas9 |
negative selection |
1265302 |
41362172 |
41362195 |
1 |
+ |
26627737 |
RPE1 |
viability after 15 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.1436174135551827 |
[569] |
[283,75] |
0 |
hSpCas9 |
negative selection |
1265303 |
41381651 |
41381674 |
1 |
+ |
26627737 |
RPE1 |
viability after 15 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.13999439938071945 |
[1518] |
[530,417] |
0 |
hSpCas9 |
negative selection |
1265304 |
41381652 |
41381675 |
1 |
+ |
26627737 |
RPE1 |
viability after 15 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.1565184096725807 |
[663] |
[104,309] |
1 |
hSpCas9 |
negative selection |
1265305 |
41381774 |
41381797 |
1 |
- |
26627737 |
RPE1 |
viability after 15 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.0917273132248426 |
[1148] |
[454,921] |
6 |
hSpCas9 |
negative selection |
1265306 |
41382512 |
41382535 |
1 |
+ |
26627737 |
RPE1 |
viability after 15 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-1.4871141387839535 |
[381] |
[63,13] |
-7 |
hSpCas9 |
negative selection |
1265307 |
41362027 |
41362050 |
1 |
+ |
26627737 |
RPE1 |
viability after 18 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.9858150118389852 |
[896] |
[128,114] |
-6 |
hSpCas9 |
negative selection |
1347617 |
41362172 |
41362195 |
1 |
+ |
26627737 |
RPE1 |
viability after 18 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.04529316204703121 |
[569] |
[223,68] |
0 |
hSpCas9 |
negative selection |
1347618 |
41381651 |
41381674 |
1 |
+ |
26627737 |
RPE1 |
viability after 18 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.1960907346294859 |
[1518] |
[352,362] |
-1 |
hSpCas9 |
negative selection |
1347619 |
41381652 |
41381675 |
1 |
+ |
26627737 |
RPE1 |
viability after 18 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.5276570695552583 |
[663] |
[223,294] |
3 |
hSpCas9 |
negative selection |
1347620 |
41381774 |
41381797 |
1 |
- |
26627737 |
RPE1 |
viability after 18 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.8877687193450041 |
[1148] |
[405,752] |
5 |
hSpCas9 |
negative selection |
1347621 |
41382512 |
41382535 |
1 |
+ |
26627737 |
RPE1 |
viability after 18 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.3438644413370868 |
[381] |
[116,42] |
-2 |
hSpCas9 |
negative selection |
1347622 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HeLa |
viability after 8 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-1.2348236172021179 |
[134] |
[12,0,55] |
-8 |
hSpCas9 |
negative selection |
1429932 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HeLa |
viability after 8 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.3103950746014198 |
[359] |
[163,171,236] |
3 |
hSpCas9 |
negative selection |
1429933 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HeLa |
viability after 8 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.21960613337182955 |
[403] |
[98,139,198] |
-2 |
hSpCas9 |
negative selection |
1429934 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HeLa |
viability after 8 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
-0.4557771976911865 |
[505] |
[113,146,206] |
-4 |
hSpCas9 |
negative selection |
1429935 |
41381774 |
41381797 |
1 |
- |
26627737 |
HeLa |
viability after 8 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.6219828875746696 |
[341] |
[270,324,108] |
5 |
hSpCas9 |
negative selection |
1429936 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HeLa |
viability after 8 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.008104801590603783 |
[248] |
[167,97,72] |
0 |
hSpCas9 |
negative selection |
1429937 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HeLa |
viability after 12 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
1.626849826636886 |
[134] |
[320,98,108] |
9 |
hSpCas9 |
negative selection |
1512247 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HeLa |
viability after 12 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.22209512261915648 |
[359] |
[131,148,240] |
2 |
hSpCas9 |
negative selection |
1512248 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HeLa |
viability after 12 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.19375879571446414 |
[403] |
[240,127,211] |
1 |
hSpCas9 |
negative selection |
1512249 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HeLa |
viability after 12 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
-0.28773259634103493 |
[505] |
[320,135,64] |
-3 |
hSpCas9 |
negative selection |
1512250 |
41381774 |
41381797 |
1 |
- |
26627737 |
HeLa |
viability after 12 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.5334451046876243 |
[341] |
[576,392,263] |
8 |
hSpCas9 |
negative selection |
1512251 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HeLa |
viability after 12 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.13808919098361572 |
[248] |
[66,128,79] |
-1 |
hSpCas9 |
negative selection |
1512252 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HeLa |
viability after 15 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
1.0992554370033651 |
[134] |
[155,87,107] |
7 |
hSpCas9 |
negative selection |
1594562 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HeLa |
viability after 15 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.12671723434589266 |
[359] |
[95,126,183] |
-1 |
hSpCas9 |
negative selection |
1594563 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HeLa |
viability after 15 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.4190653353747434 |
[403] |
[123,97,148] |
-4 |
hSpCas9 |
negative selection |
1594564 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HeLa |
viability after 15 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.16584581828662726 |
[505] |
[300,212,173] |
1 |
hSpCas9 |
negative selection |
1594565 |
41381774 |
41381797 |
1 |
- |
26627737 |
HeLa |
viability after 15 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.8431609730458278 |
[341] |
[543,708,223] |
9 |
hSpCas9 |
negative selection |
1594566 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HeLa |
viability after 15 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
0.07068001362810472 |
[248] |
[146,123,42] |
0 |
hSpCas9 |
negative selection |
1594567 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HeLa |
viability after 18 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
1.0416565396268815 |
[134] |
[105,59,107] |
7 |
hSpCas9 |
negative selection |
1676877 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HeLa |
viability after 18 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.11100226293943544 |
[359] |
[64,107,183] |
-1 |
hSpCas9 |
negative selection |
1676878 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HeLa |
viability after 18 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.3911028154107438 |
[403] |
[87,80,148] |
-3 |
hSpCas9 |
negative selection |
1676879 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HeLa |
viability after 18 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.19363783679032942 |
[505] |
[206,180,173] |
1 |
hSpCas9 |
negative selection |
1676880 |
41381774 |
41381797 |
1 |
- |
26627737 |
HeLa |
viability after 18 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.8302419476071787 |
[341] |
[361,579,223] |
9 |
hSpCas9 |
negative selection |
1676881 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HeLa |
viability after 18 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
0.061086907973423976 |
[248] |
[96,102,42] |
0 |
hSpCas9 |
negative selection |
1676882 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 6 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.4579089323808636 |
[420] |
[4,71] |
-3 |
hSpCas9 |
negative selection |
1759192 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 6 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.782166026999968 |
[589] |
[47,220] |
4 |
hSpCas9 |
negative selection |
1759193 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 6 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.4743066362739503 |
[802] |
[86,92] |
-3 |
hSpCas9 |
negative selection |
1759194 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 6 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.11984266948329644 |
[569] |
[10,144] |
0 |
hSpCas9 |
negative selection |
1759195 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 6 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
-0.5231403026100433 |
[706] |
[164,28] |
-3 |
hSpCas9 |
negative selection |
1759196 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 6 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-1.7359012744746387 |
[361] |
[38,4] |
-7 |
hSpCas9 |
negative selection |
1759197 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 8 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.5992276081527368 |
[119] |
[78,109,110] |
6 |
hSpCas9 |
negative selection |
1841507 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 8 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.031384415073460736 |
[254] |
[117,139,171] |
0 |
hSpCas9 |
negative selection |
1841508 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 8 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.07770263652684825 |
[239] |
[154,126,136] |
0 |
hSpCas9 |
negative selection |
1841509 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 8 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.4428775107824391 |
[220] |
[198,198,99] |
4 |
hSpCas9 |
negative selection |
1841510 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 8 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
-0.1551799507785886 |
[476] |
[170,221,312] |
-2 |
hSpCas9 |
negative selection |
1841511 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 8 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.7941518812020589 |
[205] |
[81,75,38] |
-7 |
hSpCas9 |
negative selection |
1841512 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 9 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
-0.5159977196865335 |
[420] |
[129,37] |
-4 |
hSpCas9 |
negative selection |
1923822 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 9 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-2.0968177183082197 |
[589] |
[47,27] |
-8 |
hSpCas9 |
negative selection |
1923823 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 9 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.6226071413324603 |
[802] |
[161,462] |
4 |
hSpCas9 |
negative selection |
1923824 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 9 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.5090251311032127 |
[569] |
[229,205] |
4 |
hSpCas9 |
negative selection |
1923825 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 9 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
-0.13400960872425996 |
[706] |
[247,111] |
-1 |
hSpCas9 |
negative selection |
1923826 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 9 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
0.6872096591271791 |
[361] |
[15,265] |
5 |
hSpCas9 |
negative selection |
1923827 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 12 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.8389387181891337 |
[119] |
[109,126,101] |
7 |
hSpCas9 |
negative selection |
2006137 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 12 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.20478476434669948 |
[254] |
[119,97,246] |
2 |
hSpCas9 |
negative selection |
2006138 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 12 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.9724772846158724 |
[239] |
[225,191,324] |
8 |
hSpCas9 |
negative selection |
2006139 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 12 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.7486818372152506 |
[220] |
[278,191,106] |
6 |
hSpCas9 |
negative selection |
2006140 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 12 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.37919927761521 |
[476] |
[354,302,316] |
4 |
hSpCas9 |
negative selection |
2006141 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 12 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
0.1410572115904633 |
[205] |
[110,165,82] |
1 |
hSpCas9 |
negative selection |
2006142 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 15 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.1046740781619182 |
[119] |
[74,121,25] |
1 |
hSpCas9 |
negative selection |
2088452 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 15 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.12284463796855544 |
[254] |
[110,103,184] |
-1 |
hSpCas9 |
negative selection |
2088453 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 15 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.410964258125897 |
[239] |
[216,163,172] |
4 |
hSpCas9 |
negative selection |
2088454 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 15 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.5986737618490262 |
[220] |
[220,241,117] |
5 |
hSpCas9 |
negative selection |
2088455 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 15 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
-0.06283712004712994 |
[476] |
[279,416,93] |
0 |
hSpCas9 |
negative selection |
2088456 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 15 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.32938029031352334 |
[205] |
[188,92,12] |
-3 |
hSpCas9 |
negative selection |
2088457 |
41362027 |
41362050 |
1 |
+ |
26627737 |
HCT116 |
viability after 18 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.17632627144835245 |
[119] |
[82,46,67] |
1 |
hSpCas9 |
negative selection |
2170767 |
41362172 |
41362195 |
1 |
+ |
26627737 |
HCT116 |
viability after 18 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.285823513649293 |
[254] |
[136,128,187] |
2 |
hSpCas9 |
negative selection |
2170768 |
41381651 |
41381674 |
1 |
+ |
26627737 |
HCT116 |
viability after 18 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.2626779669056687 |
[239] |
[127,88,206] |
2 |
hSpCas9 |
negative selection |
2170769 |
41381652 |
41381675 |
1 |
+ |
26627737 |
HCT116 |
viability after 18 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
1.0953890166209717 |
[220] |
[202,288,186] |
8 |
hSpCas9 |
negative selection |
2170770 |
41381774 |
41381797 |
1 |
- |
26627737 |
HCT116 |
viability after 18 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
-0.09164028049607464 |
[476] |
[276,244,120] |
-1 |
hSpCas9 |
negative selection |
2170771 |
41382512 |
41382535 |
1 |
+ |
26627737 |
HCT116 |
viability after 18 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.7142787472803058 |
[205] |
[49,65,65] |
-6 |
hSpCas9 |
negative selection |
2170772 |
41361939 |
41361962 |
1 |
+ |
27661255 |
K562 |
viability |
GAAGCTGCGAGCGCATCAGGTGG |
FOXO6 |
ENSG00000204060 |
0.30180228274876525 |
[705,1134] |
[982,826] |
8 |
dCas9-KRAB |
negative selection |
5480757 |
41362163 |
41362186 |
1 |
+ |
27661255 |
K562 |
viability |
GGAAAGCGAAGAGCTCTCGGCGG |
FOXO6 |
ENSG00000204060 |
0.11933285319993087 |
[592,784] |
[657,540] |
4 |
dCas9-KRAB |
negative selection |
5480758 |
41362027 |
41362050 |
1 |
+ |
27869803 |
HPAFII |
viability after 27 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.7795462631335992 |
[109] |
[41,146,NaN] |
6 |
hSpCas9 |
negative selection |
9534400 |
41362172 |
41362195 |
1 |
+ |
27869803 |
HPAFII |
viability after 27 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.3269192672965595 |
[125] |
[69,93,NaN] |
2 |
hSpCas9 |
negative selection |
9534401 |
41381651 |
41381674 |
1 |
+ |
27869803 |
HPAFII |
viability after 27 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.013934298389533584 |
[333] |
[258,102,NaN] |
0 |
hSpCas9 |
negative selection |
9534402 |
41381652 |
41381675 |
1 |
+ |
27869803 |
HPAFII |
viability after 27 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.3005729383728951 |
[325] |
[221,201,NaN] |
2 |
hSpCas9 |
negative selection |
9534403 |
41381774 |
41381797 |
1 |
- |
27869803 |
HPAFII |
viability after 27 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.1484493334350463 |
[282] |
[415,257,NaN] |
8 |
hSpCas9 |
negative selection |
9534404 |
41382512 |
41382535 |
1 |
+ |
27869803 |
HPAFII |
viability after 27 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.9077623322506165 |
[193] |
[73,37,NaN] |
-6 |
hSpCas9 |
negative selection |
9534405 |
41362027 |
41362050 |
1 |
+ |
27869803 |
HPAFII |
viability after 15 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.47336767661565227 |
[109] |
[136,180,NaN] |
5 |
hSpCas9 |
negative selection |
9616849 |
41362172 |
41362195 |
1 |
+ |
27869803 |
HPAFII |
viability after 15 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.4023764402265202 |
[125] |
[112,219,NaN] |
4 |
hSpCas9 |
negative selection |
9616850 |
41381651 |
41381674 |
1 |
+ |
27869803 |
HPAFII |
viability after 15 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
-0.22776899708891069 |
[333] |
[501,184,NaN] |
-3 |
hSpCas9 |
negative selection |
9616851 |
41381652 |
41381675 |
1 |
+ |
27869803 |
HPAFII |
viability after 15 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.11675065138260099 |
[325] |
[665,201,NaN] |
1 |
hSpCas9 |
negative selection |
9616852 |
41381774 |
41381797 |
1 |
- |
27869803 |
HPAFII |
viability after 15 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.9906159828914496 |
[282] |
[813,473,NaN] |
9 |
hSpCas9 |
negative selection |
9616853 |
41382512 |
41382535 |
1 |
+ |
27869803 |
HPAFII |
viability after 15 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.11020236976614556 |
[193] |
[342,99,NaN] |
-1 |
hSpCas9 |
negative selection |
9616854 |
41362027 |
41362050 |
1 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.0891735325525882 |
[264] |
[92,182,33] |
0 |
hSpCas9 |
negative selection |
9699298 |
41362172 |
41362195 |
1 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.08402699709225381 |
[506] |
[240,149,177] |
0 |
hSpCas9 |
negative selection |
9699299 |
41381651 |
41381674 |
1 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
1.2726829917757956 |
[655] |
[979,439,337] |
9 |
hSpCas9 |
negative selection |
9699300 |
41381652 |
41381675 |
1 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
1.175124103796666 |
[657] |
[719,728,204] |
9 |
hSpCas9 |
negative selection |
9699301 |
41381774 |
41381797 |
1 |
- |
27869803 |
ASPC1 |
viability after 36 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
0.5002665842596025 |
[691] |
[697,332,94] |
5 |
hSpCas9 |
negative selection |
9699302 |
41382512 |
41382535 |
1 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.2567289616025641 |
[609] |
[334,252,6] |
-3 |
hSpCas9 |
negative selection |
9699303 |
41362027 |
41362050 |
1 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.3461353464519261 |
[210] |
[117,97,NaN] |
4 |
hSpCas9 |
negative selection |
9781747 |
41362172 |
41362195 |
1 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.03799925949754912 |
[324] |
[84,183,NaN] |
0 |
hSpCas9 |
negative selection |
9781748 |
41381651 |
41381674 |
1 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.5272428053090217 |
[609] |
[381,325,NaN] |
6 |
hSpCas9 |
negative selection |
9781749 |
41381652 |
41381675 |
1 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.3938437847132367 |
[605] |
[397,242,NaN] |
4 |
hSpCas9 |
negative selection |
9781750 |
41381774 |
41381797 |
1 |
- |
27869803 |
PATU8988S |
viability after 35 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.4553982434251833 |
[764] |
[809,879,NaN] |
9 |
hSpCas9 |
negative selection |
9781751 |
41382512 |
41382535 |
1 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.6161768157185716 |
[412] |
[115,100,NaN] |
-6 |
hSpCas9 |
negative selection |
9781752 |
41362027 |
41362050 |
1 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
0.17156877248761782 |
[210] |
[92,96,NaN] |
2 |
hSpCas9 |
negative selection |
9864196 |
41362172 |
41362195 |
1 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
-0.010766478576271443 |
[324] |
[70,201,NaN] |
0 |
hSpCas9 |
negative selection |
9864197 |
41381651 |
41381674 |
1 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.7108373030922333 |
[609] |
[365,438,NaN] |
8 |
hSpCas9 |
negative selection |
9864198 |
41381652 |
41381675 |
1 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.4365900906859767 |
[605] |
[297,363,NaN] |
5 |
hSpCas9 |
negative selection |
9864199 |
41381774 |
41381797 |
1 |
- |
27869803 |
PATU8988S |
viability after 31 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.1442122140036597 |
[764] |
[543,839,NaN] |
9 |
hSpCas9 |
negative selection |
9864200 |
41382512 |
41382535 |
1 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-0.5180976243613076 |
[412] |
[92,142,NaN] |
-5 |
hSpCas9 |
negative selection |
9864201 |
41362027 |
41362050 |
1 |
+ |
27869803 |
HPAFII |
viability after 35 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
1.345246027834074 |
[109] |
[53,239,NaN] |
8 |
hSpCas9 |
negative selection |
9946645 |
41362172 |
41362195 |
1 |
+ |
27869803 |
HPAFII |
viability after 35 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.28008663108529974 |
[125] |
[44,113,NaN] |
1 |
hSpCas9 |
negative selection |
9946646 |
41381651 |
41381674 |
1 |
+ |
27869803 |
HPAFII |
viability after 35 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.2392150337468677 |
[333] |
[303,81,NaN] |
1 |
hSpCas9 |
negative selection |
9946647 |
41381652 |
41381675 |
1 |
+ |
27869803 |
HPAFII |
viability after 35 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.5534484147679386 |
[325] |
[300,175,NaN] |
3 |
hSpCas9 |
negative selection |
9946648 |
41381774 |
41381797 |
1 |
- |
27869803 |
HPAFII |
viability after 35 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.3425122178028215 |
[282] |
[288,446,NaN] |
8 |
hSpCas9 |
negative selection |
9946649 |
41382512 |
41382535 |
1 |
+ |
27869803 |
HPAFII |
viability after 35 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-1.4223086182325797 |
[193] |
[30,42,NaN] |
-6 |
hSpCas9 |
negative selection |
9946650 |
41362027 |
41362050 |
1 |
+ |
27869803 |
HPAFII |
viability after 31 days |
GACTTGGCCGGCGACGAGGACGG |
FOXO6 |
ENSG00000204060 |
1.0496748764311583 |
[109] |
[44,217,NaN] |
7 |
hSpCas9 |
negative selection |
10029094 |
41362172 |
41362195 |
1 |
+ |
27869803 |
HPAFII |
viability after 31 days |
AGAGCTCTCGGCGGAACGCGTGG |
FOXO6 |
ENSG00000204060 |
0.3189148584478543 |
[125] |
[36,143,NaN] |
2 |
hSpCas9 |
negative selection |
10029095 |
41381651 |
41381674 |
1 |
+ |
27869803 |
HPAFII |
viability after 31 days |
TTTCATCCGCGTGCAGAACGAGG |
FOXO6 |
ENSG00000204060 |
0.5565849863839867 |
[333] |
[413,124,NaN] |
4 |
hSpCas9 |
negative selection |
10029096 |
41381652 |
41381675 |
1 |
+ |
27869803 |
HPAFII |
viability after 31 days |
TTCATCCGCGTGCAGAACGAGGG |
FOXO6 |
ENSG00000204060 |
0.31422988448722666 |
[325] |
[293,154,NaN] |
2 |
hSpCas9 |
negative selection |
10029097 |
41381774 |
41381797 |
1 |
- |
27869803 |
HPAFII |
viability after 31 days |
TCGCCTTGCCCTTGATGCGCAGG |
FOXO6 |
ENSG00000204060 |
1.3186419613942462 |
[282] |
[421,367,NaN] |
8 |
hSpCas9 |
negative selection |
10029098 |
41382512 |
41382535 |
1 |
+ |
27869803 |
HPAFII |
viability after 31 days |
TGGACCTCGACATGTTCAGCGGG |
FOXO6 |
ENSG00000204060 |
-1.5934713330256338 |
[193] |
[48,21,NaN] |
-7 |
hSpCas9 |
negative selection |
10029099 |