Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2632
• Symbol: GBE1
• Description: 1,4-alpha-glucan branching enzyme 1

DataSource: http://genomecrispr.dkfz.de/#!/results/GBE1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
81535197	81535220	3	-	26472758	Jiyoye	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	2.4775647093972717	[9]	[41]	9	hSpCas9	negative selection	62096
81761434	81761457	3	+	26472758	Jiyoye	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.15394037726091525	[89]	[60]	-1	hSpCas9	negative selection	62097
81761388	81761411	3	-	26472758	Jiyoye	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.3733870680495901	[215]	[210]	3	hSpCas9	negative selection	62098
81499196	81499219	3	-	26472758	Jiyoye	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.08943508358194463	[257]	[206]	0	hSpCas9	negative selection	62099
81761476	81761499	3	+	26472758	Jiyoye	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	0.9642318856571451	[173]	[255]	6	hSpCas9	negative selection	62100
81705506	81705529	3	-	26472758	Jiyoye	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.08381097100626886	[103]	[73]	0	hSpCas9	negative selection	62101
81648962	81648985	3	-	26472758	Jiyoye	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.23556400343567424	[106]	[94]	1	hSpCas9	negative selection	62102
81642918	81642941	3	+	26472758	Jiyoye	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.010570600324015134	[336]	[255]	0	hSpCas9	negative selection	62103
81593908	81593931	3	-	26472758	Jiyoye	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.6442528573011295	[256]	[123]	-4	hSpCas9	negative selection	62104
81499186	81499209	3	-	26472758	Jiyoye	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.07014039422830276	[95]	[75]	0	hSpCas9	negative selection	62105
81535197	81535220	3	-	26472758	KBM7	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-1.1164882167153665	[189,119]	[32,32]	-7	hSpCas9	negative selection	253214
81761434	81761457	3	+	26472758	KBM7	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.3567546087338336	[394,364]	[351,118]	4	hSpCas9	negative selection	253215
81761388	81761411	3	-	26472758	KBM7	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.022937667724009958	[984,600]	[497,235]	0	hSpCas9	negative selection	253216
81499196	81499219	3	-	26472758	KBM7	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.1445397375222015	[722,719]	[428,329]	1	hSpCas9	negative selection	253217
81761476	81761499	3	+	26472758	KBM7	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.10277065107714371	[665,408]	[263,200]	-1	hSpCas9	negative selection	253218
81705506	81705529	3	-	26472758	KBM7	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.26819072963916396	[399,323]	[130,148]	-3	hSpCas9	negative selection	253219
81648962	81648985	3	-	26472758	KBM7	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.6236017635581199	[313,246]	[244,162]	6	hSpCas9	negative selection	253220
81642918	81642941	3	+	26472758	KBM7	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.12049577076133655	[1528,1065]	[540,564]	-1	hSpCas9	negative selection	253221
81593908	81593931	3	-	26472758	KBM7	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.09180955479175756	[855,1081]	[345,513]	-1	hSpCas9	negative selection	253222
81499186	81499209	3	-	26472758	KBM7	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.1423098906695601	[554,599]	[300,200]	-1	hSpCas9	negative selection	253223
81535197	81535220	3	-	26472758	Raji	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.3573617883819469	[36]	[10]	3	hSpCas9	negative selection	444332
81761434	81761457	3	+	26472758	Raji	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.10148293393391522	[244]	[60]	0	hSpCas9	negative selection	444333
81761388	81761411	3	-	26472758	Raji	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.25124624022971576	[390]	[107]	2	hSpCas9	negative selection	444334
81499196	81499219	3	-	26472758	Raji	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.25873515215782095	[442]	[122]	2	hSpCas9	negative selection	444335
81761476	81761499	3	+	26472758	Raji	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	0.8715705982748302	[251]	[106]	7	hSpCas9	negative selection	444336
81705506	81705529	3	-	26472758	Raji	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.825181718801848	[196]	[80]	7	hSpCas9	negative selection	444337
81648962	81648985	3	-	26472758	Raji	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.13863446935803914	[136]	[34]	1	hSpCas9	negative selection	444338
81642918	81642941	3	+	26472758	Raji	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.32977595671004756	[791]	[230]	3	hSpCas9	negative selection	444339
81593908	81593931	3	-	26472758	Raji	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.028528114662359938	[375]	[88]	0	hSpCas9	negative selection	444340
81499186	81499209	3	-	26472758	Raji	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.5112804770472431	[259]	[85]	5	hSpCas9	negative selection	444341
81535197	81535220	3	-	26472758	K562	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.09589620295635881	[91]	[82]	0	hSpCas9	negative selection	635450
81761434	81761457	3	+	26472758	K562	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	1.2015329148132703	[238]	[463]	8	hSpCas9	negative selection	635451
81761388	81761411	3	-	26472758	K562	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.5158052139340213	[487]	[588]	4	hSpCas9	negative selection	635452
81499196	81499219	3	-	26472758	K562	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	1.118887845582588	[671]	[1231]	8	hSpCas9	negative selection	635453
81761476	81761499	3	+	26472758	K562	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	0.5372757760952748	[390]	[478]	4	hSpCas9	negative selection	635454
81705506	81705529	3	-	26472758	K562	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.606988807051155	[384]	[494]	5	hSpCas9	negative selection	635455
81648962	81648985	3	-	26472758	K562	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.8274008642593624	[242]	[363]	7	hSpCas9	negative selection	635456
81642918	81642941	3	+	26472758	K562	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.5339253448614318	[1034]	[1264]	4	hSpCas9	negative selection	635457
81593908	81593931	3	-	26472758	K562	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.40966724189928616	[823]	[923]	3	hSpCas9	negative selection	635458
81499186	81499209	3	-	26472758	K562	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.3138835473295466	[445]	[467]	2	hSpCas9	negative selection	635459
81577942	81577965	3	-	26627737	DLD1	viability	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.3476743098228121	[890]	[439,274,345]	3	hSpCas9	negative selection	823077
81593908	81593931	3	-	26627737	DLD1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.5784601777466121	[533]	[102,299,333]	6	hSpCas9	negative selection	823078
81642956	81642979	3	-	26627737	DLD1	viability	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.40369472210112745	[582]	[154,317,251]	4	hSpCas9	negative selection	823079
81649854	81649877	3	+	26627737	DLD1	viability	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.19605675302737313	[1186]	[476,363,157]	-2	hSpCas9	negative selection	823080
81705477	81705500	3	-	26627737	DLD1	viability	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.09014601932828548	[219]	[102,64,30]	-1	hSpCas9	negative selection	823081
81761469	81761492	3	-	26627737	DLD1	viability	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.8074708592432859	[412]	[68,98,56]	-6	hSpCas9	negative selection	823082
81577942	81577965	3	-	26627737	GBM cells	viability after 5 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.12384602811416978	[574]	[347,217]	-2	hSpCas9	negative selection	905392
81593908	81593931	3	-	26627737	GBM cells	viability after 5 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.03988750263186902	[301]	[161,170]	0	hSpCas9	negative selection	905393
81642956	81642979	3	-	26627737	GBM cells	viability after 5 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.15855769151870525	[496]	[314,279]	2	hSpCas9	negative selection	905394
81649854	81649877	3	+	26627737	GBM cells	viability after 5 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.21522565579873898	[538]	[225,271]	-3	hSpCas9	negative selection	905395
81705477	81705500	3	-	26627737	GBM cells	viability after 5 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.6347681208917773	[151]	[62,41]	-7	hSpCas9	negative selection	905396
81761469	81761492	3	-	26627737	GBM cells	viability after 5 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.15995972762602562	[120]	[69,74]	2	hSpCas9	negative selection	905397
81577942	81577965	3	-	26627737	GBM cells	viability after 13 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.06017848464100073	[574]	[285,309]	0	hSpCas9	negative selection	987707
81593908	81593931	3	-	26627737	GBM cells	viability after 13 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.1535295676788106	[301]	[159,136]	-2	hSpCas9	negative selection	987708
81642956	81642979	3	-	26627737	GBM cells	viability after 13 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.24497199038078987	[496]	[425,232]	3	hSpCas9	negative selection	987709
81649854	81649877	3	+	26627737	GBM cells	viability after 13 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.6058056415771423	[538]	[184,197]	-6	hSpCas9	negative selection	987710
81705477	81705500	3	-	26627737	GBM cells	viability after 13 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.4413611648086697	[151]	[84,40]	-5	hSpCas9	negative selection	987711
81761469	81761492	3	-	26627737	GBM cells	viability after 13 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.3358489224511033	[120]	[78,85]	4	hSpCas9	negative selection	987712
81577942	81577965	3	-	26627737	GBM cells	viability after 21 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.11431290149610818	[574]	[309,268]	-1	hSpCas9	negative selection	1070022
81593908	81593931	3	-	26627737	GBM cells	viability after 21 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.2396742076249715	[301]	[211,176]	2	hSpCas9	negative selection	1070023
81642956	81642979	3	-	26627737	GBM cells	viability after 21 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.18025714976193852	[496]	[318,293]	2	hSpCas9	negative selection	1070024
81649854	81649877	3	+	26627737	GBM cells	viability after 21 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.5891284529354779	[538]	[190,197]	-5	hSpCas9	negative selection	1070025
81705477	81705500	3	-	26627737	GBM cells	viability after 21 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.7228765478157573	[151]	[60,39]	-6	hSpCas9	negative selection	1070026
81761469	81761492	3	-	26627737	GBM cells	viability after 21 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-1.0725891966739112	[120]	[36,25]	-7	hSpCas9	negative selection	1070027
81577942	81577965	3	-	26627737	RPE1	viability after 9 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	1.1265383107544742	[577]	[498,260]	7	hSpCas9	negative selection	1152337
81593908	81593931	3	-	26627737	RPE1	viability after 9 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.0569476142504729	[1228]	[184,677]	0	hSpCas9	negative selection	1152338
81642956	81642979	3	-	26627737	RPE1	viability after 9 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	1.1393127665629508	[778]	[579,481]	7	hSpCas9	negative selection	1152339
81649854	81649877	3	+	26627737	RPE1	viability after 9 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.1578028504496245	[2188]	[588,990]	1	hSpCas9	negative selection	1152340
81705477	81705500	3	-	26627737	RPE1	viability after 9 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.4087703725791817	[654]	[74,256]	-3	hSpCas9	negative selection	1152341
81761469	81761492	3	-	26627737	RPE1	viability after 9 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.42196423402812566	[515]	[96,150]	-3	hSpCas9	negative selection	1152342
81577942	81577965	3	-	26627737	RPE1	viability after 12 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	1.0464590561894327	[577]	[430,203]	6	hSpCas9	negative selection	1234652
81593908	81593931	3	-	26627737	RPE1	viability after 12 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.20356534523837577	[1228]	[268,497]	1	hSpCas9	negative selection	1234653
81642956	81642979	3	-	26627737	RPE1	viability after 12 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	1.3435104184128155	[778]	[364,706]	7	hSpCas9	negative selection	1234654
81649854	81649877	3	+	26627737	RPE1	viability after 12 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.6592793344703958	[2188]	[1023,827]	4	hSpCas9	negative selection	1234655
81705477	81705500	3	-	26627737	RPE1	viability after 12 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-1.17648218714499	[654]	[21,136]	-7	hSpCas9	negative selection	1234656
81761469	81761492	3	-	26627737	RPE1	viability after 12 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.49746472432278577	[515]	[70,126]	-3	hSpCas9	negative selection	1234657
81577942	81577965	3	-	26627737	RPE1	viability after 15 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	1.5279994542924888	[577]	[610,336]	7	hSpCas9	negative selection	1316967
81593908	81593931	3	-	26627737	RPE1	viability after 15 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.017648636882483748	[1228]	[262,420]	0	hSpCas9	negative selection	1316968
81642956	81642979	3	-	26627737	RPE1	viability after 15 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	1.4251933244394523	[778]	[603,579]	7	hSpCas9	negative selection	1316969
81649854	81649877	3	+	26627737	RPE1	viability after 15 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.06216039454727129	[2188]	[558,625]	0	hSpCas9	negative selection	1316970
81705477	81705500	3	-	26627737	RPE1	viability after 15 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.331888537115106	[654]	[22,266]	-2	hSpCas9	negative selection	1316971
81761469	81761492	3	-	26627737	RPE1	viability after 15 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-1.8741751061687295	[515]	[21,56]	-8	hSpCas9	negative selection	1316972
81577942	81577965	3	-	26627737	RPE1	viability after 18 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	1.1685690713935575	[577]	[441,252]	6	hSpCas9	negative selection	1399282
81593908	81593931	3	-	26627737	RPE1	viability after 18 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.36191097059581434	[1228]	[403,449]	2	hSpCas9	negative selection	1399283
81642956	81642979	3	-	26627737	RPE1	viability after 18 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	1.480892829000081	[778]	[536,639]	7	hSpCas9	negative selection	1399284
81649854	81649877	3	+	26627737	RPE1	viability after 18 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.25483928609761275	[2188]	[744,661]	1	hSpCas9	negative selection	1399285
81705477	81705500	3	-	26627737	RPE1	viability after 18 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.02222858937643396	[654]	[102,249]	0	hSpCas9	negative selection	1399286
81761469	81761492	3	-	26627737	RPE1	viability after 18 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.8046823288422263	[515]	[56,103]	-5	hSpCas9	negative selection	1399287
81577942	81577965	3	-	26627737	HeLa	viability after 8 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.2913349991969181	[539]	[345,337,197]	2	hSpCas9	negative selection	1481597
81593908	81593931	3	-	26627737	HeLa	viability after 8 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.5731023716734692	[389]	[116,113,111]	-5	hSpCas9	negative selection	1481598
81642956	81642979	3	-	26627737	HeLa	viability after 8 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.6094356726926069	[1008]	[360,149,362]	-6	hSpCas9	negative selection	1481599
81649854	81649877	3	+	26627737	HeLa	viability after 8 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.41340722275219255	[797]	[442,579,366]	4	hSpCas9	negative selection	1481600
81705477	81705500	3	-	26627737	HeLa	viability after 8 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.9580064921742563	[138]	[155,87,116]	7	hSpCas9	negative selection	1481601
81761469	81761492	3	-	26627737	HeLa	viability after 8 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	1.44418230979517	[97]	[143,119,91]	8	hSpCas9	negative selection	1481602
81577942	81577965	3	-	26627737	HeLa	viability after 12 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.628226193098205	[539]	[318,335,379]	5	hSpCas9	negative selection	1563912
81593908	81593931	3	-	26627737	HeLa	viability after 12 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.4114948288633219	[389]	[124,164,68]	-4	hSpCas9	negative selection	1563913
81642956	81642979	3	-	26627737	HeLa	viability after 12 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.42465311439949416	[1008]	[452,207,285]	-4	hSpCas9	negative selection	1563914
81649854	81649877	3	+	26627737	HeLa	viability after 12 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.24468477207369066	[797]	[544,236,410]	2	hSpCas9	negative selection	1563915
81705477	81705500	3	-	26627737	HeLa	viability after 12 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.35103979653794637	[138]	[147,6,73]	3	hSpCas9	negative selection	1563916
81761469	81761492	3	-	26627737	HeLa	viability after 12 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	2.1468667144847755	[97]	[187,257,83]	9	hSpCas9	negative selection	1563917
81577942	81577965	3	-	26627737	HeLa	viability after 15 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.6885852974734289	[539]	[372,234,462]	5	hSpCas9	negative selection	1646227
81593908	81593931	3	-	26627737	HeLa	viability after 15 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.07936772554800015	[389]	[141,224,133]	0	hSpCas9	negative selection	1646228
81642956	81642979	3	-	26627737	HeLa	viability after 15 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.06072262672088247	[1008]	[377,381,533]	0	hSpCas9	negative selection	1646229
81649854	81649877	3	+	26627737	HeLa	viability after 15 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.041142001966717245	[797]	[379,374,239]	0	hSpCas9	negative selection	1646230
81705477	81705500	3	-	26627737	HeLa	viability after 15 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.2783903925795921	[138]	[1,108,97]	2	hSpCas9	negative selection	1646231
81761469	81761492	3	-	26627737	HeLa	viability after 15 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	2.208933634027796	[97]	[153,163,239]	9	hSpCas9	negative selection	1646232
81577942	81577965	3	-	26627737	HeLa	viability after 18 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.6599600086789877	[539]	[241,187,462]	5	hSpCas9	negative selection	1728542
81593908	81593931	3	-	26627737	HeLa	viability after 18 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.10686157980109245	[389]	[100,186,133]	0	hSpCas9	negative selection	1728543
81642956	81642979	3	-	26627737	HeLa	viability after 18 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.0812286621794771	[1008]	[264,316,533]	0	hSpCas9	negative selection	1728544
81649854	81649877	3	+	26627737	HeLa	viability after 18 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.015226562614037764	[797]	[242,310,239]	0	hSpCas9	negative selection	1728545
81705477	81705500	3	-	26627737	HeLa	viability after 18 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.28329097612406495	[138]	[1,89,97]	2	hSpCas9	negative selection	1728546
81761469	81761492	3	-	26627737	HeLa	viability after 18 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	2.234575659747115	[97]	[107,137,239]	9	hSpCas9	negative selection	1728547
81577942	81577965	3	-	26627737	HCT116	viability after 6 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.046016268892033474	[934]	[298,55]	0	hSpCas9	negative selection	1810857
81593908	81593931	3	-	26627737	HCT116	viability after 6 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.4301549310777261	[632]	[48,180]	2	hSpCas9	negative selection	1810858
81642956	81642979	3	-	26627737	HCT116	viability after 6 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.9986827971268162	[1551]	[163,98]	-5	hSpCas9	negative selection	1810859
81649854	81649877	3	+	26627737	HCT116	viability after 6 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	1.2570354214611408	[1019]	[370,389]	6	hSpCas9	negative selection	1810860
81705477	81705500	3	-	26627737	HCT116	viability after 6 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	1.1524524533418412	[506]	[55,243]	6	hSpCas9	negative selection	1810861
81761469	81761492	3	-	26627737	HCT116	viability after 6 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	2.2793408817842753	[442]	[903,25]	9	hSpCas9	negative selection	1810862
81577942	81577965	3	-	26627737	HCT116	viability after 8 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.05546699051319992	[664]	[402,324,330]	0	hSpCas9	negative selection	1893172
81593908	81593931	3	-	26627737	HCT116	viability after 8 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.34031329438913116	[444]	[243,148,188]	-4	hSpCas9	negative selection	1893173
81642956	81642979	3	-	26627737	HCT116	viability after 8 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.6627573686984939	[296]	[341,199,236]	6	hSpCas9	negative selection	1893174
81649854	81649877	3	+	26627737	HCT116	viability after 8 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.8311329185049358	[988]	[207,303,403]	-8	hSpCas9	negative selection	1893175
81705477	81705500	3	-	26627737	HCT116	viability after 8 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.8772979345134797	[75]	[69,111,48]	7	hSpCas9	negative selection	1893176
81761469	81761492	3	-	26627737	HCT116	viability after 8 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.39111533884440675	[178]	[80,90,53]	-4	hSpCas9	negative selection	1893177
81577942	81577965	3	-	26627737	HCT116	viability after 9 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.25958635752291753	[934]	[250,174]	-2	hSpCas9	negative selection	1975487
81593908	81593931	3	-	26627737	HCT116	viability after 9 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.08036279047667182	[632]	[60,237]	0	hSpCas9	negative selection	1975488
81642956	81642979	3	-	26627737	HCT116	viability after 9 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.10122068054834332	[1551]	[654,173]	0	hSpCas9	negative selection	1975489
81649854	81649877	3	+	26627737	HCT116	viability after 9 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	1.3024701874830136	[1019]	[382,899]	8	hSpCas9	negative selection	1975490
81705477	81705500	3	-	26627737	HCT116	viability after 9 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	-0.7871422998117712	[506]	[159,13]	-5	hSpCas9	negative selection	1975491
81761469	81761492	3	-	26627737	HCT116	viability after 9 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.13188922638449074	[442]	[180,88]	1	hSpCas9	negative selection	1975492
81577942	81577965	3	-	26627737	HCT116	viability after 12 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.4076735261815603	[664]	[550,417,412]	4	hSpCas9	negative selection	2057802
81593908	81593931	3	-	26627737	HCT116	viability after 12 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.5819683561235004	[444]	[113,180,177]	-6	hSpCas9	negative selection	2057803
81642956	81642979	3	-	26627737	HCT116	viability after 12 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.8200576408664157	[296]	[272,320,233]	7	hSpCas9	negative selection	2057804
81649854	81649877	3	+	26627737	HCT116	viability after 12 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.9824035458446083	[988]	[151,182,461]	-8	hSpCas9	negative selection	2057805
81705477	81705500	3	-	26627737	HCT116	viability after 12 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	1.3427173044357281	[75]	[60,41,202]	8	hSpCas9	negative selection	2057806
81761469	81761492	3	-	26627737	HCT116	viability after 12 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.024969974542302875	[178]	[85,53,136]	0	hSpCas9	negative selection	2057807
81577942	81577965	3	-	26627737	HCT116	viability after 15 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.2121520148753795	[664]	[447,611,269]	2	hSpCas9	negative selection	2140117
81593908	81593931	3	-	26627737	HCT116	viability after 15 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.6424756721591312	[444]	[145,179,162]	-6	hSpCas9	negative selection	2140118
81642956	81642979	3	-	26627737	HCT116	viability after 15 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.7750250532568851	[296]	[357,260,264]	6	hSpCas9	negative selection	2140119
81649854	81649877	3	+	26627737	HCT116	viability after 15 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.9909178805817535	[988]	[255,168,426]	-7	hSpCas9	negative selection	2140120
81705477	81705500	3	-	26627737	HCT116	viability after 15 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	1.270027327474318	[75]	[90,30,190]	8	hSpCas9	negative selection	2140121
81761469	81761492	3	-	26627737	HCT116	viability after 15 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.5095445432683131	[178]	[80,113,234]	5	hSpCas9	negative selection	2140122
81577942	81577965	3	-	26627737	HCT116	viability after 18 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.1693506260218609	[664]	[416,403,255]	1	hSpCas9	negative selection	2222432
81593908	81593931	3	-	26627737	HCT116	viability after 18 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-1.1302909152292735	[444]	[136,80,76]	-7	hSpCas9	negative selection	2222433
81642956	81642979	3	-	26627737	HCT116	viability after 18 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.5680138147433489	[296]	[220,205,211]	5	hSpCas9	negative selection	2222434
81649854	81649877	3	+	26627737	HCT116	viability after 18 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.83917594312233	[988]	[260,207,339]	-6	hSpCas9	negative selection	2222435
81705477	81705500	3	-	26627737	HCT116	viability after 18 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	2.119232616859238	[75]	[174,23,294]	9	hSpCas9	negative selection	2222436
81761469	81761492	3	-	26627737	HCT116	viability after 18 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.26113445607190894	[178]	[57,114,138]	2	hSpCas9	negative selection	2222437
81761976	81761999	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCCTTCAAATTGGACATAAGG	GBE1	ENSG00000114480	-0.3719051018966012	[139,179]	[34,17]	-2	dCas9-VP64	positive selection	2383307
81761889	81761912	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTGAGCGAGGTCAGCTTGGG	GBE1	ENSG00000114480	0.201197959438002	[47,83]	[11,21]	1	dCas9-VP64	positive selection	2383308
81761951	81761974	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGTCAGTGGGTGCTTAAGTGGG	GBE1	ENSG00000114480	1.2262570131879564	[454,344]	[100,318]	5	dCas9-VP64	positive selection	2383309
81623684	81623707	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTTGG	GBE1	ENSG00000114480	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385634
81761976	81761999	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCCTTCAAATTGGACATAAGG	GBE1	ENSG00000114480	3.140278928360898	[303,160]	[1371,21]	9	dCas9-VP64	positive selection	2478562
81761889	81761912	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTGAGCGAGGTCAGCTTGGG	GBE1	ENSG00000114480	1.4502998200081234	[39,50]	[33,46]	7	dCas9-VP64	positive selection	2478563
81761951	81761974	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGTCAGTGGGTGCTTAAGTGGG	GBE1	ENSG00000114480	2.0672081467201933	[383,331]	[75,879]	8	dCas9-VP64	positive selection	2478564
81623684	81623707	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTTGG	GBE1	ENSG00000114480	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480889
81761372	81761395	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0.22384584776409366	[0,0]	[0,0]	5	hSpCas9	positive selection	2990139
81761388	81761411	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.02421464372023656	[3,3]	[3,1]	0	hSpCas9	positive selection	2990140
81761477	81761500	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.8436267458600866	[3,3]	[0,1]	-8	hSpCas9	positive selection	2990141
81649871	81649894	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	0.13849936442870409	[4,4]	[4,3]	3	hSpCas9	positive selection	2990142
81761372	81761395	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3057997
81761388	81761411	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.5040882531662807	[3,3]	[3,0]	-7	hSpCas9	positive selection	3057998
81761477	81761500	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.047804251771701306	[3,3]	[1,2]	0	hSpCas9	positive selection	3057999
81649871	81649894	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	0.3477342268378034	[4,4]	[4,3]	6	hSpCas9	positive selection	3058000
81642956	81642979		-	24336571	A375	resistance to PLX after 7 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.16300484929921102	[9,12]	[8,10]	-5	hSpCas9	positive selection	3116096
81642780	81642803		-	24336571	A375	resistance to PLX after 7 days	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.00718198239280754	[21,16]	[19,19]	0	hSpCas9	positive selection	3116098
81593958	81593981		-	24336571	A375	resistance to PLX after 7 days	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	-0.14594120342653932	[10,11]	[8,11]	-5	hSpCas9	positive selection	3116099
81642956	81642979		-	24336571	A375	resistance to PLX after 14 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.047763516694840136	[11,6]	[3,4]	0	hSpCas9	positive selection	3173889
81642780	81642803		-	24336571	A375	resistance to PLX after 14 days	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.43953854253192703	[17,18]	[10,10]	4	hSpCas9	positive selection	3173891
81593958	81593981		-	24336571	A375	resistance to PLX after 14 days	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	-0.2239317399189428	[18,11]	[5,4]	-2	hSpCas9	positive selection	3173892
81642956	81642979		-	24336571	A375	viability after 7 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.5224123294877383	[17]	[9,12]	-6	hSpCas9	negative selection	3231682
81642780	81642803		-	24336571	A375	viability after 7 days	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.17834433066562455	[17]	[21,16]	2	hSpCas9	negative selection	3231684
81593958	81593981		-	24336571	A375	viability after 7 days	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.2540337662427559	[9]	[10,11]	4	hSpCas9	negative selection	3231685
81642956	81642979		-	24336571	A375	viability after 14 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.7221552453053184	[17]	[11,6]	-7	hSpCas9	negative selection	3289475
81642780	81642803		-	24336571	A375	viability after 14 days	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.08125444675567578	[17]	[17,18]	1	hSpCas9	negative selection	3289477
81593958	81593981		-	24336571	A375	viability after 14 days	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6782922694274949	[9]	[18,11]	8	hSpCas9	negative selection	3289478
81593958	81593981	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.5218642078700165	[114,97]	[0,0]	2	hSpCas9	positive selection	3351138
81642780	81642803	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.6937489465390139	[241,252]	[0,0]	-5	hSpCas9	positive selection	3351139
81642807	81642830	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.3157021176544518	[177,202]	[0,0]	-2	hSpCas9	positive selection	3351140
81593984	81594007	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	6.605249514866141	[54,54]	[34,34]	9	hSpCas9	positive selection	3370345
81591149	81591172	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	-1.2583736268382073	[365,365]	[0,0]	-8	hSpCas9	positive selection	3370346
81591036	81591059	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.49756129071763344	[215,215]	[0,0]	-3	hSpCas9	positive selection	3370347
81761371	81761394	3	+	26780180	HT29	viability (Avana library 4 designs)	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0	[]	[]	0	hSpCas9	negative selection	3427276
81761388	81761411	3	-	26780180	HT29	viability (Avana library 4 designs)	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	1.08514104814179	[]	[]	4	hSpCas9	negative selection	3427277
81761476	81761499	3	+	26780180	HT29	viability (Avana library 4 designs)	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	1.01479565316481	[]	[]	4	hSpCas9	negative selection	3427278
81649871	81649894	3	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	-0.0334360798985661	[]	[]	0	hSpCas9	negative selection	3427279
81761476	81761499	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	6.03871182275014	[]	[]	9	hSpCas9	negative selection	3510806
81649871	81649894	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	3.12977858806564	[]	[]	5	hSpCas9	negative selection	3510807
81761388	81761411	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	2.17003844288696	[]	[]	3	hSpCas9	negative selection	3510808
81761371	81761394	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0	[]	[]	0	hSpCas9	negative selection	3510809
81649854	81649877	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	1.3242430866328	[]	[]	1	hSpCas9	negative selection	3510810
81642902	81642925	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTGTGTACCACATCTAAGAGG	GBE1	ENSG00000114480	-0.519151468832648	[]	[]	0	hSpCas9	negative selection	3510811
81761476	81761499	3	+	26780180	A375	viability (Avana lentiGuide)	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	7.4025322415192	[]	[]	6	hSpCas9	negative selection	3619465
81649871	81649894	3	-	26780180	A375	viability (Avana lentiGuide)	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	-0.0217016680168207	[]	[]	0	hSpCas9	negative selection	3619466
81761388	81761411	3	-	26780180	A375	viability (Avana lentiGuide)	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	5.12199573356307	[]	[]	4	hSpCas9	negative selection	3619467
81761371	81761394	3	+	26780180	A375	viability (Avana lentiGuide)	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0	[]	[]	0	hSpCas9	negative selection	3619468
81649854	81649877	3	+	26780180	A375	viability (Avana lentiGuide)	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	5.9579535722071	[]	[]	5	hSpCas9	negative selection	3619469
81642902	81642925	3	+	26780180	A375	viability (Avana lentiGuide)	GGCTGTGTACCACATCTAAGAGG	GBE1	ENSG00000114480	-3.78019038961773	[]	[]	-6	hSpCas9	negative selection	3619470
81761476	81761499	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	0.3191427978127419	[4]	[5,5]	8	hSpCas9	positive selection	3728124
81649871	81649894	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	-0.0027163495994773357	[5]	[6,4]	0	hSpCas9	positive selection	3728125
81761388	81761411	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.2821652650540824	[4]	[3,2]	-4	hSpCas9	positive selection	3728126
81761371	81761394	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0.05947611385637419	[0]	[0,0]	1	hSpCas9	positive selection	3728127
81649854	81649877	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.20229800881337506	[4]	[5,4]	5	hSpCas9	positive selection	3728128
81642902	81642925	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTGTGTACCACATCTAAGAGG	GBE1	ENSG00000114480	0.10567597128913972	[4]	[5,4]	2	hSpCas9	positive selection	3728129
81761476	81761499	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.04019496621998299	[4]	[4,3]	0	hSpCas9	positive selection	3836731
81649871	81649894	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGTATCGTATTTCACCGTGG	GBE1	ENSG00000114480	-0.3426582635518498	[6]	[4,2]	-4	hSpCas9	positive selection	3836732
81761388	81761411	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.2858351861485116	[5]	[1,5]	-4	hSpCas9	positive selection	3836733
81761371	81761394	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	0.24644513604583196	[0]	[0,0]	6	hSpCas9	positive selection	3836734
81649854	81649877	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.09417389019281242	[5]	[4,5]	2	hSpCas9	positive selection	3836735
81642902	81642925	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTGTGTACCACATCTAAGAGG	GBE1	ENSG00000114480	0.20977834432289355	[5]	[5,4]	5	hSpCas9	positive selection	3836736
81591036	81591059	3	-	26780180	A375	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.852398839161835	[]	[]	3	hSpCas9	negative selection	3943138
81642807	81642830	3	-	26780180	A375	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.178020083084379	[]	[]	0	hSpCas9	negative selection	3943139
81642780	81642803	3	-	26780180	A375	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	1.22971123436428	[]	[]	6	hSpCas9	negative selection	3943140
81593984	81594007	3	-	26780180	A375	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	1.03729688044654	[]	[]	5	hSpCas9	negative selection	3943141
81591149	81591172	3	-	26780180	A375	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.52853714316067	[]	[]	1	hSpCas9	negative selection	3943142
81593958	81593981	3	-	26780180	A375	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.584963146199479	[]	[]	1	hSpCas9	negative selection	3943143
81591036	81591059	3	-	26780180	HT29	viability (GeCKOv2 library)	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	1.24408185257306	[]	[]	6	hSpCas9	negative selection	4051104
81642807	81642830	3	-	26780180	HT29	viability (GeCKOv2 library)	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.662725640045876	[]	[]	2	hSpCas9	negative selection	4051105
81642780	81642803	3	-	26780180	HT29	viability (GeCKOv2 library)	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.425515703365148	[]	[]	1	hSpCas9	negative selection	4051106
81593984	81594007	3	-	26780180	HT29	viability (GeCKOv2 library)	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.782258882440079	[]	[]	3	hSpCas9	negative selection	4051107
81591149	81591172	3	-	26780180	HT29	viability (GeCKOv2 library)	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	1.01666138236949	[]	[]	4	hSpCas9	negative selection	4051108
81593958	81593981	3	-	26780180	HT29	viability (GeCKOv2 library)	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	1.09232110390765	[]	[]	5	hSpCas9	negative selection	4051109
81642956	81642979	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.21939580588188096	[3]	[1,1]	-5	hSpCas9	positive selection	4139252
81642780	81642803	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.12827114214148352	[4]	[2,3]	3	hSpCas9	positive selection	4139254
81593958	81593981	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	-0.01992418765274323	[3]	[1,2]	0	hSpCas9	positive selection	4139255
81642956	81642979	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.9324098605862453	[3]	[2,0,0,4]	6	hSpCas9	positive selection	4203274
81642780	81642803	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.4975180990570737	[3]	[3,2,3,0]	3	hSpCas9	positive selection	4203276
81593958	81593981	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.9041520247724506	[3]	[0,1,2,4]	6	hSpCas9	positive selection	4203277
81593958	81593981	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.3019410210278479	[2]	[2,1]	6	hSpCas9	positive selection	4272404
81642780	81642803	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.29382251803261655	[3]	[3,3]	6	hSpCas9	positive selection	4272405
81642807	81642830	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.05905909168970913	[3]	[3,1]	-1	hSpCas9	positive selection	4272406
81593984	81594007	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.2022191093148062	[2]	[2,0]	-4	hSpCas9	positive selection	4336668
81591149	81591172	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.18177885244565695	[3]	[3,3]	3	hSpCas9	positive selection	4336669
81591036	81591059	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.22563612681035755	[3]	[2,1]	-4	hSpCas9	positive selection	4336670
81649816	81649838	3	-	27760321	OCIAML3	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-3.2987000956212995	[11,12]	[0,0]	-9	hSpCas9	negative selection	4403072
81649870	81649892	3	-	27760321	OCIAML3	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-1.2603991522903044	[205,184]	[71,52]	-8	hSpCas9	negative selection	4403073
81670915	81670937	3	-	27760321	OCIAML3	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-3.4604298127181035	[63,44]	[5,0]	-9	hSpCas9	negative selection	4403074
81761391	81761413	3	+	27760321	OCIAML3	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.04868362834747342	[349,260]	[234,257]	0	hSpCas9	negative selection	4403075
81642911	81642933	3	-	27760321	OCIAML3	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.03665885129025881	[60,48]	[42,39]	0	hSpCas9	negative selection	4403076
81649816	81649838	3	-	27760321	OCIAML2	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-0.008852386496098319	[11,12]	[13,4]	0	hSpCas9	negative selection	4486535
81649870	81649892	3	-	27760321	OCIAML2	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	0.044299881959726894	[205,184]	[114,225]	0	hSpCas9	negative selection	4486536
81670915	81670937	3	-	27760321	OCIAML2	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.8363987103207338	[63,44]	[4,49]	-7	hSpCas9	negative selection	4486537
81761391	81761413	3	+	27760321	OCIAML2	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-0.05525805105552395	[349,260]	[224,249]	0	hSpCas9	negative selection	4486538
81642911	81642933	3	-	27760321	OCIAML2	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	0.019488745442045374	[60,48]	[46,41]	0	hSpCas9	negative selection	4486539
81649816	81649838	3	-	27760321	MV411	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-3.0536215267066176	[11,12]	[0,0]	-9	hSpCas9	negative selection	4569998
81649870	81649892	3	-	27760321	MV411	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-1.9230340723224182	[205,184]	[11,66]	-8	hSpCas9	negative selection	4569999
81670915	81670937	3	-	27760321	MV411	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	1.5289156802021764	[63,44]	[148,32]	9	hSpCas9	negative selection	4570000
81761391	81761413	3	+	27760321	MV411	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-1.0550816003114332	[349,260]	[74,127]	-6	hSpCas9	negative selection	4570001
81642911	81642933	3	-	27760321	MV411	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-5.173476453301204	[60,48]	[0,0]	-9	hSpCas9	negative selection	4570002
81649816	81649838	3	-	27760321	HL60	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	2.0559018472309125	[11,12]	[33,51]	9	hSpCas9	negative selection	4653461
81649870	81649892	3	-	27760321	HL60	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	0.22471057256848026	[205,184]	[232,136]	2	hSpCas9	negative selection	4653462
81670915	81670937	3	-	27760321	HL60	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.22634154347288904	[63,44]	[8,67]	-3	hSpCas9	negative selection	4653463
81761391	81761413	3	+	27760321	HL60	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-0.6522309843404728	[349,260]	[137,177]	-6	hSpCas9	negative selection	4653464
81642911	81642933	3	-	27760321	HL60	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	0.24246781871284595	[60,48]	[80,22]	3	hSpCas9	negative selection	4653465
81649816	81649838	3	-	27760321	HT1080	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	3.4664952857471825	[12,9]	[20,82]	9	hSpCas9	negative selection	4736924
81649870	81649892	3	-	27760321	HT1080	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-4.498158824971552	[184,144]	[0,4]	-8	hSpCas9	negative selection	4736925
81670915	81670937	3	-	27760321	HT1080	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	3.317529724631573	[44,34]	[228,81]	9	hSpCas9	negative selection	4736926
81761391	81761413	3	+	27760321	HT1080	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-6.533400840742515	[260,203]	[0,0]	-9	hSpCas9	negative selection	4736927
81642911	81642933	3	-	27760321	HT1080	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-4.114558017842154	[48,37]	[0,0]	-8	hSpCas9	negative selection	4736928
81649816	81649838	3	-	27760321	HT29	viability after 7 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-2.755304038184308	[12,9]	[4,0,0]	-9	hSpCas9	negative selection	4820387
81649870	81649892	3	-	27760321	HT29	viability after 7 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.20896676932306746	[184,144]	[161,156,226]	-3	hSpCas9	negative selection	4820388
81670915	81670937	3	-	27760321	HT29	viability after 7 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	0.0038935641412574107	[44,34]	[79,69,9]	0	hSpCas9	negative selection	4820389
81761391	81761413	3	+	27760321	HT29	viability after 7 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.1488967556846768	[260,203]	[451,383,179]	2	hSpCas9	negative selection	4820390
81642911	81642933	3	-	27760321	HT29	viability after 7 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.6448871054164238	[48,37]	[55,46,7]	-7	hSpCas9	negative selection	4820391
81649816	81649838	3	-	27760321	HT29	viability after 25 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-1.521590884859024	[12,9]	[9,1,0]	-7	hSpCas9	negative selection	4903850
81649870	81649892	3	-	27760321	HT29	viability after 25 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.8952224540201403	[184,144]	[84,67,157]	-6	hSpCas9	negative selection	4903851
81670915	81670937	3	-	27760321	HT29	viability after 25 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.0024750618747453323	[44,34]	[79,48,0]	0	hSpCas9	negative selection	4903852
81761391	81761413	3	+	27760321	HT29	viability after 25 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.616989205025672	[260,203]	[218,502,523]	7	hSpCas9	negative selection	4903853
81642911	81642933	3	-	27760321	HT29	viability after 25 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.5424505100708861	[48,37]	[66,26,2]	-5	hSpCas9	negative selection	4903854
81649816	81649838	3	-	27760321	HT29	viability after 22 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-3.3185133743608928	[12,9]	[0,1,0]	-9	hSpCas9	negative selection	4987313
81649870	81649892	3	-	27760321	HT29	viability after 22 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.4738583581427145	[184,144]	[86,136,189]	-4	hSpCas9	negative selection	4987314
81670915	81670937	3	-	27760321	HT29	viability after 22 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-1.273851059390176	[44,34]	[25,29,0]	-7	hSpCas9	negative selection	4987315
81761391	81761413	3	+	27760321	HT29	viability after 22 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.8038369721681311	[260,203]	[436,569,400]	8	hSpCas9	negative selection	4987316
81642911	81642933	3	-	27760321	HT29	viability after 22 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.9830582745895144	[48,37]	[3,33,38]	-6	hSpCas9	negative selection	4987317
81649816	81649838	3	-	27760321	HT29	viability after 19 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-3.7156118204841073	[12,9]	[0,0,0]	-9	hSpCas9	negative selection	5070776
81649870	81649892	3	-	27760321	HT29	viability after 19 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.19010447760545812	[184,144]	[214,28,253]	-2	hSpCas9	negative selection	5070777
81670915	81670937	3	-	27760321	HT29	viability after 19 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.0020095284526071566	[44,34]	[58,76,3]	0	hSpCas9	negative selection	5070778
81761391	81761413	3	+	27760321	HT29	viability after 19 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-0.037669163454195354	[260,203]	[191,344,233]	0	hSpCas9	negative selection	5070779
81642911	81642933	3	-	27760321	HT29	viability after 19 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-1.4739703806896287	[48,37]	[18,21,12]	-7	hSpCas9	negative selection	5070780
81649816	81649838	3	-	27760321	HT29	viability after 16 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-2.3368169350166275	[12,9]	[5,0,0]	-8	hSpCas9	negative selection	5154239
81649870	81649892	3	-	27760321	HT29	viability after 16 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.6866867405498487	[184,144]	[133,74,137]	-6	hSpCas9	negative selection	5154240
81670915	81670937	3	-	27760321	HT29	viability after 16 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.9221943047909784	[44,34]	[63,9,0]	-7	hSpCas9	negative selection	5154241
81761391	81761413	3	+	27760321	HT29	viability after 16 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.5977236290851208	[260,203]	[532,322,339]	7	hSpCas9	negative selection	5154242
81642911	81642933	3	-	27760321	HT29	viability after 16 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	0.08782490364909945	[48,37]	[86,29,41]	0	hSpCas9	negative selection	5154243
81649816	81649838	3	-	27760321	HT29	viability after 13 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-0.9546184607637684	[12,9]	[5,13,0]	-7	hSpCas9	negative selection	5237702
81649870	81649892	3	-	27760321	HT29	viability after 13 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.42762187086735026	[184,144]	[92,86,240]	-5	hSpCas9	negative selection	5237703
81670915	81670937	3	-	27760321	HT29	viability after 13 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.21935303886707302	[44,34]	[54,15,47]	-3	hSpCas9	negative selection	5237704
81761391	81761413	3	+	27760321	HT29	viability after 13 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.5415430536392732	[260,203]	[406,381,388]	7	hSpCas9	negative selection	5237705
81642911	81642933	3	-	27760321	HT29	viability after 13 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.14276662948047436	[48,37]	[13,57,63]	-2	hSpCas9	negative selection	5237706
81649816	81649838	3	-	27760321	HT29	viability after 10 days	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-3.112614817723432	[12,9]	[1,1,0]	-9	hSpCas9	negative selection	5321165
81649870	81649892	3	-	27760321	HT29	viability after 10 days	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-0.9155454938165899	[184,144]	[182,101,43]	-7	hSpCas9	negative selection	5321166
81670915	81670937	3	-	27760321	HT29	viability after 10 days	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-0.9130081551899467	[44,34]	[58,0,18]	-7	hSpCas9	negative selection	5321167
81761391	81761413	3	+	27760321	HT29	viability after 10 days	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	0.6344946874475978	[260,203]	[481,376,489]	8	hSpCas9	negative selection	5321168
81642911	81642933	3	-	27760321	HT29	viability after 10 days	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	0.8219619050698714	[48,37]	[168,24,91]	9	hSpCas9	negative selection	5321169
81649816	81649838	3	-	27760321	MOLM13	viability	AATTATGATTGGATACACTGGG	GBE1	ENSG00000114480	-2.8275647138790223	[11,12]	[0,0]	-8	hSpCas9	negative selection	5404628
81649870	81649892	3	-	27760321	MOLM13	viability	TTGTATCGTATTTCACCGTGGG	GBE1	ENSG00000114480	-4.2986529256889625	[205,184]	[10,0]	-9	hSpCas9	negative selection	5404629
81670915	81670937	3	-	27760321	MOLM13	viability	TCGTACCCATACAAAAAACTGG	GBE1	ENSG00000114480	-4.926455327009252	[63,44]	[0,0]	-9	hSpCas9	negative selection	5404630
81761391	81761413	3	+	27760321	MOLM13	viability	CGGCGTAGGGCTTCAAGTACGG	GBE1	ENSG00000114480	-1.13780091450872	[349,260]	[41,107]	-6	hSpCas9	negative selection	5404631
81642911	81642933	3	-	27760321	MOLM13	viability	ATCATAGTCCTCTTAGATGTGG	GBE1	ENSG00000114480	-0.2859420013340155	[60,48]	[0,45]	-2	hSpCas9	negative selection	5404632
81761371	81761394	3	+	27661255	K562	viability	GTACCTGCGCTGGAAGTCCACGG	GBE1	ENSG00000114480	-0.020864632676917044	[709,576]	[595,433]	-1	dCas9-KRAB	negative selection	5481651
81761486	81761509	3	+	27661255	K562	viability	GGCCGAGCCGCGGGAGTCATCGG	GBE1	ENSG00000114480	-0.13397460681845458	[955,1248]	[842,760]	-5	dCas9-KRAB	negative selection	5481652
81761541	81761564	3	+	27661255	K562	viability	GAGGCCCGAGAGGTCGAGTGGGG	GBE1	ENSG00000114480	-0.05339668471601201	[876,695]	[743,491]	-2	dCas9-KRAB	negative selection	5481653
81761579	81761602	3	+	27661255	K562	viability	GAGCTCTAGCTGGGACGCGGCGG	GBE1	ENSG00000114480	-0.10026131502732571	[149,140]	[134,85]	-4	dCas9-KRAB	negative selection	5481654
81761616	81761639	3	+	27661255	K562	viability	GAGGGCGCCTAGGCGTGTCGAGG	GBE1	ENSG00000114480	0.10884686378087638	[1233,1397]	[1116,1142]	4	dCas9-KRAB	negative selection	5481655
81761198	81761221	3	-	27661255	K562	viability	GGGTTCTGTGGCTTCCGTAGTGG	GBE1	ENSG00000114480	-0.30649350004111875	[1220,1073]	[811,683]	-7	dCas9-KRAB	negative selection	5481656
81593958	81593981	3	-	27260156	BXPC3	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.4998871705713222	[246]	[332,314,397,426]	9	hSpCas9	negative selection	5544864
81642780	81642803	3	-	27260156	BXPC3	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.1491823056174042	[969]	[1095,1042,1160,1209]	3	hSpCas9	negative selection	5544865
81642807	81642830	3	-	27260156	BXPC3	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.05720233343518921	[659]	[658,625,768,840]	1	hSpCas9	negative selection	5544866
81593984	81594007	3	-	27260156	BXPC3	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.2082587272700529	[254]	[203,303,309,439]	4	hSpCas9	negative selection	5609128
81591149	81591172	3	-	27260156	BXPC3	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.1976639297099413	[894]	[882,1004,1181,1265]	4	hSpCas9	negative selection	5609129
81591036	81591059	3	-	27260156	BXPC3	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.23973244055444648	[566]	[458,413,503,656]	-5	hSpCas9	negative selection	5609130
81593958	81593981	3	-	27260156	A673	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.4169674972702164	[246]	[397,376,363,447]	8	hSpCas9	negative selection	5666115
81642780	81642803	3	-	27260156	A673	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.1417410475818136	[969]	[1300,891,1089,964]	-4	hSpCas9	negative selection	5666116
81642807	81642830	3	-	27260156	A673	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.06036200372311873	[659]	[997,776,778,767]	1	hSpCas9	negative selection	5666117
81593984	81594007	3	-	27260156	A673	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.03732101584411174	[254]	[229,349,397,263]	0	hSpCas9	negative selection	5730379
81591149	81591172	3	-	27260156	A673	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.20208222362203265	[894]	[1311,981,1281,1389]	5	hSpCas9	negative selection	5730380
81591036	81591059	3	-	27260156	A673	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.39613755341434564	[566]	[489,527,540,504]	-7	hSpCas9	negative selection	5730381
81593958	81593981	3	-	27260156	A375	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.7702444953124692	[246]	[554,362,466,555]	9	hSpCas9	negative selection	5787366
81642780	81642803	3	-	27260156	A375	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.28491368335409717	[969]	[859,811,1169,864]	-4	hSpCas9	negative selection	5787367
81642807	81642830	3	-	27260156	A375	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.10813844900386615	[659]	[938,747,869,760]	1	hSpCas9	negative selection	5787368
81593984	81594007	3	-	27260156	A375	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.17752847767140112	[254]	[322,377,235,145]	-3	hSpCas9	negative selection	5851630
81591149	81591172	3	-	27260156	A375	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.46986237701804223	[894]	[1590,1409,1292,1482]	7	hSpCas9	negative selection	5851631
81591036	81591059	3	-	27260156	A375	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.43302192129185924	[566]	[492,772,459,296]	-6	hSpCas9	negative selection	5851632
81593958	81593981	3	-	27260156	COLO741	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.3058269326445342	[246]	[386,430,353]	6	hSpCas9	negative selection	5908617
81642780	81642803	3	-	27260156	COLO741	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.102657120488989	[969]	[1126,1674,1181]	2	hSpCas9	negative selection	5908618
81642807	81642830	3	-	27260156	COLO741	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.08488439104530143	[659]	[852,919,903]	1	hSpCas9	negative selection	5908619
81593984	81594007	3	-	27260156	COLO741	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.18192746125526038	[254]	[338,501,271]	4	hSpCas9	negative selection	5972881
81591149	81591172	3	-	27260156	COLO741	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.19886594809972602	[894]	[1398,1440,1116]	4	hSpCas9	negative selection	5972882
81591036	81591059	3	-	27260156	COLO741	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.3422736942941406	[566]	[676,503,542]	-6	hSpCas9	negative selection	5972883
81593958	81593981	3	-	27260156	CAL120	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.5288388360846127	[246]	[582,314,452]	7	hSpCas9	negative selection	6029868
81642780	81642803	3	-	27260156	CAL120	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.07210755381425538	[969]	[1765,840,933]	-1	hSpCas9	negative selection	6029869
81642807	81642830	3	-	27260156	CAL120	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.12542133311339126	[659]	[586,811,832]	-2	hSpCas9	negative selection	6029870
81593984	81594007	3	-	27260156	CAL120	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.9003342958489545	[254]	[179,135,194]	-8	hSpCas9	negative selection	6094132
81591149	81591172	3	-	27260156	CAL120	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.49248014305918775	[894]	[2249,1113,1440]	7	hSpCas9	negative selection	6094133
81591036	81591059	3	-	27260156	CAL120	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.027206970711357636	[566]	[814,684,671]	0	hSpCas9	negative selection	6094134
81593958	81593981	3	-	27260156	CADOES1	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.7853798996070612	[246]	[476,382,315,407]	9	hSpCas9	negative selection	6151119
81642780	81642803	3	-	27260156	CADOES1	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.1620362171551668	[969]	[804,771,769,880]	-3	hSpCas9	negative selection	6151120
81642807	81642830	3	-	27260156	CADOES1	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.3434079583754225	[659]	[999,741,558,814]	6	hSpCas9	negative selection	6151121
81593984	81594007	3	-	27260156	CADOES1	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.25493569241261926	[254]	[393,239,256,238]	4	hSpCas9	negative selection	6215383
81591149	81591172	3	-	27260156	CADOES1	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.3283346163196187	[894]	[876,1113,1146,1042]	5	hSpCas9	negative selection	6215384
81591036	81591059	3	-	27260156	CADOES1	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.19551571212102442	[566]	[526,776,484,627]	3	hSpCas9	negative selection	6215385
81593958	81593981	3	-	27260156	EWS502	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6430195551481521	[246]	[373,447,373,440]	9	hSpCas9	negative selection	6272370
81642780	81642803	3	-	27260156	EWS502	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.08337960031611624	[969]	[795,1157,697,1252]	-1	hSpCas9	negative selection	6272371
81642807	81642830	3	-	27260156	EWS502	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.3060367348900265	[659]	[1140,735,853,680]	5	hSpCas9	negative selection	6272372
81593984	81594007	3	-	27260156	EWS502	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.1336936237735089	[254]	[180,413,227,374]	2	hSpCas9	negative selection	6336634
81591149	81591172	3	-	27260156	EWS502	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.17881880231562952	[894]	[1042,1243,996,993]	3	hSpCas9	negative selection	6336635
81591036	81591059	3	-	27260156	EWS502	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.19488429632818013	[566]	[486,602,553,448]	-3	hSpCas9	negative selection	6336636
81593958	81593981	3	-	27260156	EW8	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6698309234220076	[246]	[224,395,335,302]	9	hSpCas9	negative selection	6393621
81642780	81642803	3	-	27260156	EW8	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.2096282200910239	[969]	[666,589,703,749]	-4	hSpCas9	negative selection	6393622
81642807	81642830	3	-	27260156	EW8	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.13045230319870005	[659]	[605,672,388,707]	2	hSpCas9	negative selection	6393623
81593984	81594007	3	-	27260156	EW8	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.07279351825717728	[254]	[232,226,160,258]	1	hSpCas9	negative selection	6457885
81591149	81591172	3	-	27260156	EW8	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.24729368965533494	[894]	[826,786,835,990]	4	hSpCas9	negative selection	6457886
81591036	81591059	3	-	27260156	EW8	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.6123562464329291	[566]	[331,248,297,325]	-8	hSpCas9	negative selection	6457887
81593958	81593981	3	-	27260156	CORL105	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.199453727040783	[246]	[368,327,278,344]	4	hSpCas9	negative selection	6514872
81642780	81642803	3	-	27260156	CORL105	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.08190196333496824	[969]	[1223,1031,1068,971]	-1	hSpCas9	negative selection	6514873
81642807	81642830	3	-	27260156	CORL105	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.02086339147389049	[659]	[778,734,796,826]	0	hSpCas9	negative selection	6514874
81593984	81594007	3	-	27260156	CORL105	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.21579870869936413	[254]	[345,225,256,202]	-4	hSpCas9	negative selection	6579136
81591149	81591172	3	-	27260156	CORL105	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.361033182724663	[894]	[1656,1288,1319,1124]	6	hSpCas9	negative selection	6579137
81591036	81591059	3	-	27260156	CORL105	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.2552478670085353	[566]	[620,379,614,622]	-5	hSpCas9	negative selection	6579138
81593958	81593981	3	-	27260156	HS294T	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6959191342655209	[246]	[160,209,103,137]	8	hSpCas9	negative selection	6636123
81642780	81642803	3	-	27260156	HS294T	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.03761414632826443	[969]	[312,294,588,344]	0	hSpCas9	negative selection	6636124
81642807	81642830	3	-	27260156	HS294T	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.29928357454770194	[659]	[299,329,180,470]	4	hSpCas9	negative selection	6636125
81593984	81594007	3	-	27260156	HS294T	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.3522330451486724	[254]	[104,190,109,90]	5	hSpCas9	negative selection	6700387
81591149	81591172	3	-	27260156	HS294T	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.4823507509431727	[894]	[377,425,368,828]	6	hSpCas9	negative selection	6700388
81591036	81591059	3	-	27260156	HS294T	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.28158983603372884	[566]	[127,166,142,309]	-4	hSpCas9	negative selection	6700389
81593958	81593981	3	-	27260156	HCC44	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.2858354984638133	[246]	[414,220,434,328]	4	hSpCas9	negative selection	6757374
81642780	81642803	3	-	27260156	HCC44	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.12161494725724298	[969]	[1085,1333,1334,1009]	2	hSpCas9	negative selection	6757375
81642807	81642830	3	-	27260156	HCC44	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.13950449972876783	[659]	[854,383,894,666]	-2	hSpCas9	negative selection	6757376
81593984	81594007	3	-	27260156	HCC44	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.2784338322317941	[254]	[487,355,151,376]	4	hSpCas9	negative selection	6821638
81591149	81591172	3	-	27260156	HCC44	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.16683098139598396	[894]	[1412,854,1329,1039]	2	hSpCas9	negative selection	6821639
81591036	81591059	3	-	27260156	HCC44	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.25209222203613707	[566]	[365,594,579,589]	-4	hSpCas9	negative selection	6821640
81593958	81593981	3	-	27260156	G402	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.7806491810425208	[246]	[1313,242,367,255]	8	hSpCas9	negative selection	6878625
81642780	81642803	3	-	27260156	G402	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.15796801170185493	[969]	[1060,641,1579,937]	-2	hSpCas9	negative selection	6878626
81642807	81642830	3	-	27260156	G402	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.26962312142558365	[659]	[1514,754,1031,658]	3	hSpCas9	negative selection	6878627
81593984	81594007	3	-	27260156	G402	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.46281447645382057	[254]	[942,264,365,214]	6	hSpCas9	negative selection	6942889
81591149	81591172	3	-	27260156	G402	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.5612937653126208	[894]	[1464,2271,1556,1183]	7	hSpCas9	negative selection	6942890
81591036	81591059	3	-	27260156	G402	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.19692553268971424	[566]	[942,785,830,637]	2	hSpCas9	negative selection	6942891
81593958	81593981	3	-	27260156	L33	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6207813948136054	[246]	[395,169,233,335]	9	hSpCas9	negative selection	6999876
81642780	81642803	3	-	27260156	L33	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.14036099657211532	[969]	[1003,449,754,975]	3	hSpCas9	negative selection	6999877
81642807	81642830	3	-	27260156	L33	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.1384937671773997	[659]	[728,250,509,752]	3	hSpCas9	negative selection	6999878
81593984	81594007	3	-	27260156	L33	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.2935271374563785	[254]	[375,175,142,215]	6	hSpCas9	negative selection	7064140
81591149	81591172	3	-	27260156	L33	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	-0.011838412847957502	[894]	[813,307,557,1096]	0	hSpCas9	negative selection	7064141
81591036	81591059	3	-	27260156	L33	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.20723321222125662	[566]	[558,227,257,436]	-5	hSpCas9	negative selection	7064142
81593958	81593981	3	-	27260156	K562	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.8642112987517289	[246]	[543,483,233,353]	9	hSpCas9	negative selection	7121127
81642780	81642803	3	-	27260156	K562	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.14959768939899243	[969]	[824,977,730,601]	-2	hSpCas9	negative selection	7121128
81642807	81642830	3	-	27260156	K562	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.38027614559753165	[659]	[737,747,866,697]	5	hSpCas9	negative selection	7121129
81593984	81594007	3	-	27260156	K562	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.2424006212585671	[254]	[250,165,359,283]	3	hSpCas9	negative selection	7185391
81591149	81591172	3	-	27260156	K562	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.7749051440356148	[894]	[2387,1121,924,1097]	8	hSpCas9	negative selection	7185392
81591036	81591059	3	-	27260156	K562	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.5808232294938755	[566]	[461,438,283,191]	-6	hSpCas9	negative selection	7185393
81593958	81593981	3	-	27260156	HT29	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.48928203782258717	[246]	[495,433,430,338]	8	hSpCas9	negative selection	7242378
81642780	81642803	3	-	27260156	HT29	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.14370294146287765	[969]	[1205,1403,1510,1105]	2	hSpCas9	negative selection	7242379
81642807	81642830	3	-	27260156	HT29	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.016989757502073544	[659]	[941,954,719,664]	0	hSpCas9	negative selection	7242380
81593984	81594007	3	-	27260156	HT29	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.04204329013835095	[254]	[289,334,280,361]	0	hSpCas9	negative selection	7306642
81591149	81591172	3	-	27260156	HT29	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.35288476266761004	[894]	[1805,1375,1378,1058]	7	hSpCas9	negative selection	7306643
81591036	81591059	3	-	27260156	HT29	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.028424947745625234	[566]	[690,872,571,590]	0	hSpCas9	negative selection	7306644
81593958	81593981	3	-	27260156	MHHES1	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.2818659292222553	[246]	[414,201,300,405]	5	hSpCas9	negative selection	7363629
81642780	81642803	3	-	27260156	MHHES1	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.13861124327068297	[969]	[1217,1286,1250,1068]	2	hSpCas9	negative selection	7363630
81642807	81642830	3	-	27260156	MHHES1	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.25265641445410103	[659]	[1068,929,763,803]	4	hSpCas9	negative selection	7363631
81593984	81594007	3	-	27260156	MHHES1	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.1999957802935749	[254]	[455,339,386,180]	3	hSpCas9	negative selection	7427893
81591149	81591172	3	-	27260156	MHHES1	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.4032985859854695	[894]	[1616,1382,1442,981]	7	hSpCas9	negative selection	7427894
81591036	81591059	3	-	27260156	MHHES1	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.01385962618388581	[566]	[745,474,858,511]	0	hSpCas9	negative selection	7427895
81593958	81593981	3	-	27260156	MEWO	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.2121499660925944	[246]	[272,275,254]	4	hSpCas9	negative selection	7484880
81642780	81642803	3	-	27260156	MEWO	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.0771084446856869	[969]	[910,743,935]	-2	hSpCas9	negative selection	7484881
81642807	81642830	3	-	27260156	MEWO	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.10632809147986383	[659]	[819,451,496]	-2	hSpCas9	negative selection	7484882
81593984	81594007	3	-	27260156	MEWO	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.3103546294955022	[254]	[359,264,274]	6	hSpCas9	negative selection	7549144
81591149	81591172	3	-	27260156	MEWO	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.046778160512148115	[894]	[1103,637,899]	1	hSpCas9	negative selection	7549145
81591036	81591059	3	-	27260156	MEWO	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.18428161724954079	[566]	[493,408,502]	-4	hSpCas9	negative selection	7549146
81593958	81593981	3	-	27260156	LNCAPCLONEFGC	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6393041857743609	[246]	[277,263,383,479]	8	hSpCas9	negative selection	7606131
81642780	81642803	3	-	27260156	LNCAPCLONEFGC	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.134490422884741	[969]	[1070,998,983,801]	2	hSpCas9	negative selection	7606132
81642807	81642830	3	-	27260156	LNCAPCLONEFGC	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.2237507262963282	[659]	[593,660,787,766]	3	hSpCas9	negative selection	7606133
81593984	81594007	3	-	27260156	LNCAPCLONEFGC	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.08941404316759904	[254]	[278,196,220,171]	-1	hSpCas9	negative selection	7670395
81591149	81591172	3	-	27260156	LNCAPCLONEFGC	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.34775832430535825	[894]	[1051,898,1249,965]	5	hSpCas9	negative selection	7670396
81591036	81591059	3	-	27260156	LNCAPCLONEFGC	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.314979674612645	[566]	[433,339,421,460]	-5	hSpCas9	negative selection	7670397
81593958	81593981	3	-	27260156	PANC0327	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.12317047221416966	[246]	[460,214,147,152]	1	hSpCas9	negative selection	7727382
81642780	81642803	3	-	27260156	PANC0327	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.07170530792031493	[969]	[998,909,843,875]	1	hSpCas9	negative selection	7727383
81642807	81642830	3	-	27260156	PANC0327	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.18348524205162137	[659]	[495,515,403,646]	-3	hSpCas9	negative selection	7727384
81593984	81594007	3	-	27260156	PANC0327	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.09782333275405997	[254]	[209,183,201,253]	-1	hSpCas9	negative selection	7791646
81591149	81591172	3	-	27260156	PANC0327	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.28506112871161104	[894]	[913,669,1218,1105]	4	hSpCas9	negative selection	7791647
81591036	81591059	3	-	27260156	PANC0327	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.02945869501006612	[566]	[632,609,330,395]	0	hSpCas9	negative selection	7791648
81593958	81593981	3	-	27260156	NCIH2009	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.9788454132616186	[246]	[887,810,378]	9	hSpCas9	negative selection	7848633
81642780	81642803	3	-	27260156	NCIH2009	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.018686248811014217	[969]	[1734,1260,1193]	0	hSpCas9	negative selection	7848634
81642807	81642830	3	-	27260156	NCIH2009	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.16908543611990434	[659]	[1065,946,1102]	2	hSpCas9	negative selection	7848635
81593984	81594007	3	-	27260156	NCIH2009	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.07633365341157983	[254]	[529,252,375]	1	hSpCas9	negative selection	7912897
81591149	81591172	3	-	27260156	NCIH2009	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.31594920408792115	[894]	[1523,1210,1931]	4	hSpCas9	negative selection	7912898
81591036	81591059	3	-	27260156	NCIH2009	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.27491664610509675	[566]	[681,461,827]	-4	hSpCas9	negative selection	7912899
81593958	81593981	3	-	27260156	NCIH1373	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.9738386283716975	[246]	[631,442,667,116]	8	hSpCas9	negative selection	7969884
81642780	81642803	3	-	27260156	NCIH1373	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.30136231407965974	[969]	[1539,1482,1347,255]	3	hSpCas9	negative selection	7969885
81642807	81642830	3	-	27260156	NCIH1373	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.4222006399844791	[659]	[587,1282,1108,229]	4	hSpCas9	negative selection	7969886
81593984	81594007	3	-	27260156	NCIH1373	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.46923745235787717	[254]	[337,142,218,38]	-5	hSpCas9	negative selection	8034148
81591149	81591172	3	-	27260156	NCIH1373	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.8659633759824156	[894]	[1997,1344,1371,717]	8	hSpCas9	negative selection	8034149
81591036	81591059	3	-	27260156	NCIH1373	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.03631032946952889	[566]	[609,534,624,188]	0	hSpCas9	negative selection	8034150
81593958	81593981	3	-	27260156	PATU8902	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.36796432923835243	[246]	[716,255,344,479]	4	hSpCas9	negative selection	8091135
81642780	81642803	3	-	27260156	PATU8902	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.5187507513579206	[969]	[1595,2470,1254,2675]	5	hSpCas9	negative selection	8091136
81642807	81642830	3	-	27260156	PATU8902	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.4686008128452973	[659]	[1216,1509,1208,1143]	5	hSpCas9	negative selection	8091137
81593984	81594007	3	-	27260156	PATU8902	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.5900657393799338	[254]	[659,301,648,484]	6	hSpCas9	negative selection	8155399
81591149	81591172	3	-	27260156	PATU8902	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.634340353304181	[894]	[2579,2148,1416,1672]	6	hSpCas9	negative selection	8155400
81591036	81591059	3	-	27260156	PATU8902	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.03568152876598474	[566]	[840,747,599,1134]	0	hSpCas9	negative selection	8155401
81593958	81593981	3	-	27260156	PANC1	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.2223355868723461	[246]	[266,380,236,144]	3	hSpCas9	negative selection	8212386
81642780	81642803	3	-	27260156	PANC1	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.10270564706703933	[969]	[781,1059,898,863]	1	hSpCas9	negative selection	8212387
81642807	81642830	3	-	27260156	PANC1	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.3146260416486214	[659]	[539,870,867,587]	5	hSpCas9	negative selection	8212388
81593984	81594007	3	-	27260156	PANC1	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.0823838918394636	[254]	[220,341,151,230]	1	hSpCas9	negative selection	8276650
81591149	81591172	3	-	27260156	PANC1	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.31244704648859944	[894]	[1028,779,1125,848]	5	hSpCas9	negative selection	8276651
81591036	81591059	3	-	27260156	PANC1	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.03812375904111903	[566]	[441,605,634,356]	0	hSpCas9	negative selection	8276652
81593958	81593981	3	-	27260156	PANC0813	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.3105754975847683	[246]	[443,394,316,293]	5	hSpCas9	negative selection	8333637
81642780	81642803	3	-	27260156	PANC0813	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.39315875420261537	[969]	[1370,1750,1447,1405]	6	hSpCas9	negative selection	8333638
81642807	81642830	3	-	27260156	PANC0813	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.41855797349424373	[659]	[941,1027,1113,1049]	6	hSpCas9	negative selection	8333639
81593984	81594007	3	-	27260156	PANC0813	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.21739297591922668	[254]	[250,221,200,349]	-3	hSpCas9	negative selection	8397901
81591149	81591172	3	-	27260156	PANC0813	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.15531403800176202	[894]	[1139,1460,1197,894]	2	hSpCas9	negative selection	8397902
81591036	81591059	3	-	27260156	PANC0813	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.06584372687566897	[566]	[799,591,536,857]	1	hSpCas9	negative selection	8397903
81593958	81593981	3	-	27260156	RDES	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.549887537577354	[246]	[447,348,419,433]	8	hSpCas9	negative selection	8454888
81642780	81642803	3	-	27260156	RDES	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.18358502005151522	[969]	[889,1267,1276,1752]	3	hSpCas9	negative selection	8454889
81642807	81642830	3	-	27260156	RDES	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.24032405694231995	[659]	[813,800,870,1133]	4	hSpCas9	negative selection	8454890
81593984	81594007	3	-	27260156	RDES	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.06455638946109721	[254]	[278,149,367,468]	1	hSpCas9	negative selection	8519152
81591149	81591172	3	-	27260156	RDES	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.35452881431301997	[894]	[1071,1322,1398,1514]	5	hSpCas9	negative selection	8519153
81591036	81591059	3	-	27260156	RDES	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.10473547459469379	[566]	[401,621,733,714]	-2	hSpCas9	negative selection	8519154
81593958	81593981	3	-	27260156	PC3	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.33669277260991504	[246]	[107,331,414,506]	7	hSpCas9	negative selection	8576139
81642780	81642803	3	-	27260156	PC3	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.0484359119041009	[969]	[541,928,1864,1125]	1	hSpCas9	negative selection	8576140
81642807	81642830	3	-	27260156	PC3	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.06365170651340946	[659]	[438,728,1131,659]	1	hSpCas9	negative selection	8576141
81593984	81594007	3	-	27260156	PC3	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.3981896197292514	[254]	[152,328,609,413]	8	hSpCas9	negative selection	8640403
81591149	81591172	3	-	27260156	PC3	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	-0.08965799029779897	[894]	[486,871,1108,1075]	-2	hSpCas9	negative selection	8640404
81591036	81591059	3	-	27260156	PC3	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.1798669257819327	[566]	[259,486,774,651]	-4	hSpCas9	negative selection	8640405
81593958	81593981	3	-	27260156	PATU8988T	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.15492713310649042	[246]	[199,347,214,311]	2	hSpCas9	negative selection	8697390
81642780	81642803	3	-	27260156	PATU8988T	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.09512623318279279	[969]	[626,1066,822,1022]	-2	hSpCas9	negative selection	8697391
81642807	81642830	3	-	27260156	PATU8988T	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.19955753879881877	[659]	[482,823,872,757]	3	hSpCas9	negative selection	8697392
81593984	81594007	3	-	27260156	PATU8988T	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.02484109549694391	[254]	[240,202,244,278]	0	hSpCas9	negative selection	8761654
81591149	81591172	3	-	27260156	PATU8988T	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.29238198135255555	[894]	[1192,1120,702,1244]	5	hSpCas9	negative selection	8761655
81591036	81591059	3	-	27260156	PATU8988T	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.43568342817946093	[566]	[462,333,347,474]	-6	hSpCas9	negative selection	8761656
81593958	81593981	3	-	27260156	T47D	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.1246490537833872	[246]	[400,226,352,279]	2	hSpCas9	negative selection	8818641
81642780	81642803	3	-	27260156	T47D	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.13255581718112075	[969]	[1334,1112,1368,1143]	3	hSpCas9	negative selection	8818642
81642807	81642830	3	-	27260156	T47D	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.0038823778890427207	[659]	[735,717,853,778]	0	hSpCas9	negative selection	8818643
81593984	81594007	3	-	27260156	T47D	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.2981870225793567	[254]	[363,287,375,441]	6	hSpCas9	negative selection	8882905
81591149	81591172	3	-	27260156	T47D	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.2344849051626322	[894]	[1386,1055,1199,1280]	5	hSpCas9	negative selection	8882906
81591036	81591059	3	-	27260156	T47D	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.3844838912257856	[566]	[454,446,578,547]	-7	hSpCas9	negative selection	8882907
81593958	81593981	3	-	27260156	SU8686	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.37398844391867436	[246]	[345,272,233,432]	6	hSpCas9	negative selection	8939892
81642780	81642803	3	-	27260156	SU8686	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.32447571169995215	[969]	[880,1213,1114,1713]	5	hSpCas9	negative selection	8939893
81642807	81642830	3	-	27260156	SU8686	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.20077155639583733	[659]	[664,602,909,878]	3	hSpCas9	negative selection	8939894
81593984	81594007	3	-	27260156	SU8686	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	-0.03860324918243896	[254]	[216,189,274,324]	0	hSpCas9	negative selection	9004156
81591149	81591172	3	-	27260156	SU8686	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.2687884679634446	[894]	[858,961,1196,1334]	4	hSpCas9	negative selection	9004157
81591036	81591059	3	-	27260156	SU8686	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.09633178779551424	[566]	[493,518,584,503]	-2	hSpCas9	negative selection	9004158
81593958	81593981	3	-	27260156	SKES1	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.01859498241676394	[246]	[293,294,196,224]	0	hSpCas9	negative selection	9061143
81642780	81642803	3	-	27260156	SKES1	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.027393760794516275	[969]	[1427,1006,744,838]	0	hSpCas9	negative selection	9061144
81642807	81642830	3	-	27260156	SKES1	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.1398055359236713	[659]	[831,845,763,506]	3	hSpCas9	negative selection	9061145
81593984	81594007	3	-	27260156	SKES1	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.14111419615950271	[254]	[341,297,265,229]	3	hSpCas9	negative selection	9125407
81591149	81591172	3	-	27260156	SKES1	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.13774391447041767	[894]	[1033,817,1156,903]	3	hSpCas9	negative selection	9125408
81591036	81591059	3	-	27260156	SKES1	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.18387988298811755	[566]	[500,465,541,475]	-4	hSpCas9	negative selection	9125409
81593958	81593981	3	-	27260156	TOV112D	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6559991740979729	[246]	[272,545,335,430]	9	hSpCas9	negative selection	9182394
81642780	81642803	3	-	27260156	TOV112D	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.014008131949633462	[969]	[844,1462,643,1006]	0	hSpCas9	negative selection	9182395
81642807	81642830	3	-	27260156	TOV112D	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	0.19297544913840659	[659]	[758,901,837,563]	4	hSpCas9	negative selection	9182396
81593984	81594007	3	-	27260156	TOV112D	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.07861076576973414	[254]	[261,253,257,298]	1	hSpCas9	negative selection	9246658
81591149	81591172	3	-	27260156	TOV112D	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.3253415562140666	[894]	[1328,1183,1067,946]	6	hSpCas9	negative selection	9246659
81591036	81591059	3	-	27260156	TOV112D	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.016385901692169358	[566]	[392,862,307,735]	0	hSpCas9	negative selection	9246660
81593958	81593981	3	-	27260156	TC71	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.379393324936632	[246]	[196,310,383,496]	8	hSpCas9	negative selection	9303645
81642780	81642803	3	-	27260156	TC71	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	-0.11275284285853593	[969]	[790,1060,892,1116]	-3	hSpCas9	negative selection	9303646
81642807	81642830	3	-	27260156	TC71	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.050790489519697724	[659]	[597,603,759,774]	-1	hSpCas9	negative selection	9303647
81593984	81594007	3	-	27260156	TC71	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.21112599676798205	[254]	[322,319,274,350]	5	hSpCas9	negative selection	9367909
81591149	81591172	3	-	27260156	TC71	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.2180023908821015	[894]	[1160,1073,997,1240]	5	hSpCas9	negative selection	9367910
81591036	81591059	3	-	27260156	TC71	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	-0.2150826151261959	[566]	[548,530,509,502]	-5	hSpCas9	negative selection	9367911
81593958	81593981	3	-	27260156	TC32	viability	TTGGAAGAATATCGCTTTGATGG	GBE1	ENSG00000114480	0.6026517626037424	[246]	[358,262,479,340]	8	hSpCas9	negative selection	9424896
81642780	81642803	3	-	27260156	TC32	viability	GCAGATTGTTTGCCTACTCCAGG	GBE1	ENSG00000114480	0.10261400535764809	[969]	[935,678,1206,1206]	2	hSpCas9	negative selection	9424897
81642807	81642830	3	-	27260156	TC32	viability	CTAGAGGGACTCATGATCTTTGG	GBE1	ENSG00000114480	-0.12091255049016814	[659]	[512,468,727,611]	-2	hSpCas9	negative selection	9424898
81593984	81594007	3	-	27260156	TC32	viability	TCCTTCTGTCAAACATAAGATGG	GBE1	ENSG00000114480	0.45782292296006355	[254]	[367,288,436,223]	7	hSpCas9	negative selection	9489160
81591149	81591172	3	-	27260156	TC32	viability	TTCTAAGGTCAAGGTTTCTCAGG	GBE1	ENSG00000114480	0.43957291456492353	[894]	[899,955,1613,1210]	7	hSpCas9	negative selection	9489161
81591036	81591059	3	-	27260156	TC32	viability	CGATTCTATAACAATAGCTGAGG	GBE1	ENSG00000114480	0.05705013103215062	[566]	[555,547,597,483]	1	hSpCas9	negative selection	9489162
81577942	81577965	3	-	27869803	HPAFII	viability after 27 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.16278902043109067	[440]	[186,319,NaN]	1	hSpCas9	negative selection	9586148
81593908	81593931	3	-	27869803	HPAFII	viability after 27 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.40861253948858955	[268]	[232,149,NaN]	3	hSpCas9	negative selection	9586149
81642956	81642979	3	-	27869803	HPAFII	viability after 27 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.2895628061110692	[495]	[447,210,NaN]	2	hSpCas9	negative selection	9586150
81649854	81649877	3	+	27869803	HPAFII	viability after 27 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.23977397125658495	[437]	[464,110,NaN]	2	hSpCas9	negative selection	9586151
81705477	81705500	3	-	27869803	HPAFII	viability after 27 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.12578884094623044	[99]	[76,40,NaN]	1	hSpCas9	negative selection	9586152
81761469	81761492	3	-	27869803	HPAFII	viability after 27 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.8459997330630746	[209]	[132,252,NaN]	7	hSpCas9	negative selection	9586153
81577942	81577965	3	-	27869803	HPAFII	viability after 15 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.2129886693266091	[440]	[456,378,NaN]	-2	hSpCas9	negative selection	9668597
81593908	81593931	3	-	27869803	HPAFII	viability after 15 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.21088288928304716	[268]	[571,186,NaN]	2	hSpCas9	negative selection	9668598
81642956	81642979	3	-	27869803	HPAFII	viability after 15 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.17339407882812063	[495]	[877,428,NaN]	2	hSpCas9	negative selection	9668599
81649854	81649877	3	+	27869803	HPAFII	viability after 15 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.6848358286192888	[437]	[863,689,NaN]	7	hSpCas9	negative selection	9668600
81705477	81705500	3	-	27869803	HPAFII	viability after 15 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.6081509078668114	[99]	[214,131,NaN]	7	hSpCas9	negative selection	9668601
81761469	81761492	3	-	27869803	HPAFII	viability after 15 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.8602528077255871	[209]	[553,319,NaN]	8	hSpCas9	negative selection	9668602
81577942	81577965	3	-	27869803	ASPC1	viability after 36 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.2458963368798368	[1260]	[719,300,552]	2	hSpCas9	negative selection	9751046
81593908	81593931	3	-	27869803	ASPC1	viability after 36 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.45353351583344814	[702]	[312,283,389]	4	hSpCas9	negative selection	9751047
81642956	81642979	3	-	27869803	ASPC1	viability after 36 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.00801239502663098	[1032]	[302,210,510]	0	hSpCas9	negative selection	9751048
81649854	81649877	3	+	27869803	ASPC1	viability after 36 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.18075760576706323	[1327]	[854,446,350]	1	hSpCas9	negative selection	9751049
81705477	81705500	3	-	27869803	ASPC1	viability after 36 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.1392864909902084	[319]	[147,19,185]	1	hSpCas9	negative selection	9751050
81761469	81761492	3	-	27869803	ASPC1	viability after 36 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.37629330083394014	[469]	[111,292,217]	4	hSpCas9	negative selection	9751051
81577942	81577965	3	-	27869803	PATU8988S	viability after 35 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.15639474886552718	[950]	[369,483,NaN]	1	hSpCas9	negative selection	9833495
81593908	81593931	3	-	27869803	PATU8988S	viability after 35 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.5461745457917909	[597]	[137,191,NaN]	-5	hSpCas9	negative selection	9833496
81642956	81642979	3	-	27869803	PATU8988S	viability after 35 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.48800980663587284	[906]	[241,278,NaN]	-5	hSpCas9	negative selection	9833497
81649854	81649877	3	+	27869803	PATU8988S	viability after 35 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.03785315741499673	[935]	[459,273,NaN]	0	hSpCas9	negative selection	9833498
81705477	81705500	3	-	27869803	PATU8988S	viability after 35 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.10758254090448105	[249]	[100,115,NaN]	1	hSpCas9	negative selection	9833499
81761469	81761492	3	-	27869803	PATU8988S	viability after 35 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.5576927192183686	[529]	[153,135,NaN]	-5	hSpCas9	negative selection	9833500
81577942	81577965	3	-	27869803	PATU8988S	viability after 31 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	0.12515837140843555	[950]	[274,589,NaN]	1	hSpCas9	negative selection	9915944
81593908	81593931	3	-	27869803	PATU8988S	viability after 31 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.27992334046112105	[597]	[169,229,NaN]	-3	hSpCas9	negative selection	9915945
81642956	81642979	3	-	27869803	PATU8988S	viability after 31 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	-0.5301839382223645	[906]	[238,264,NaN]	-5	hSpCas9	negative selection	9915946
81649854	81649877	3	+	27869803	PATU8988S	viability after 31 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	-0.10196024992141961	[935]	[334,363,NaN]	-1	hSpCas9	negative selection	9915947
81705477	81705500	3	-	27869803	PATU8988S	viability after 31 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.12727566482868458	[249]	[107,109,NaN]	1	hSpCas9	negative selection	9915948
81761469	81761492	3	-	27869803	PATU8988S	viability after 31 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	-0.6495980354715543	[529]	[117,155,NaN]	-6	hSpCas9	negative selection	9915949
81577942	81577965	3	-	27869803	HPAFII	viability after 35 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.24142063391146107	[440]	[130,253,NaN]	-1	hSpCas9	negative selection	9998393
81593908	81593931	3	-	27869803	HPAFII	viability after 35 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	1.157484116506666	[268]	[442,146,NaN]	7	hSpCas9	negative selection	9998394
81642956	81642979	3	-	27869803	HPAFII	viability after 35 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.8793326821943067	[495]	[499,418,NaN]	6	hSpCas9	negative selection	9998395
81649854	81649877	3	+	27869803	HPAFII	viability after 35 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.2152982222320141	[437]	[398,97,NaN]	1	hSpCas9	negative selection	9998396
81705477	81705500	3	-	27869803	HPAFII	viability after 35 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	1.3057035574419136	[99]	[63,193,NaN]	8	hSpCas9	negative selection	9998397
81761469	81761492	3	-	27869803	HPAFII	viability after 35 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.8421336518494515	[209]	[64,331,NaN]	5	hSpCas9	negative selection	9998398
81577942	81577965	3	-	27869803	HPAFII	viability after 31 days	ACGCATGGGCTTGGTGGAGAAGG	GBE1	ENSG00000114480	-0.21249580908207144	[440]	[159,271,NaN]	-1	hSpCas9	negative selection	10080842
81593908	81593931	3	-	27869803	HPAFII	viability after 31 days	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.5512561656142708	[268]	[281,154,NaN]	4	hSpCas9	negative selection	10080843
81642956	81642979	3	-	27869803	HPAFII	viability after 31 days	ACCTGAAGAGCTACAAGAACTGG	GBE1	ENSG00000114480	0.5468186929598883	[495]	[342,475,NaN]	4	hSpCas9	negative selection	10080844
81649854	81649877	3	+	27869803	HPAFII	viability after 31 days	CGAACCACATACTTTGCCCACGG	GBE1	ENSG00000114480	0.2922038168337864	[437]	[434,154,NaN]	2	hSpCas9	negative selection	10080845
81705477	81705500	3	-	27869803	HPAFII	viability after 31 days	ATACTGCAAAGAATGGGCCCCGG	GBE1	ENSG00000114480	0.43771368113852416	[99]	[53,99,NaN]	3	hSpCas9	negative selection	10080846
81761469	81761492	3	-	27869803	HPAFII	viability after 31 days	TCGGCCCGAGGACTACGAGGCGG	GBE1	ENSG00000114480	0.9572040351157904	[209]	[101,366,NaN]	7	hSpCas9	negative selection	10080847
81535197	81535220	3	-	28162770	P31FUJ	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.42544728235677454	[31]	[27]	-4	hSpCas9	negative selection	10161001
81761434	81761457	3	+	28162770	P31FUJ	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.8993784706891869	[199]	[125]	-6	hSpCas9	negative selection	10161002
81761388	81761411	3	-	28162770	P31FUJ	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.3251134205122208	[340]	[501]	3	hSpCas9	negative selection	10161003
81499196	81499219	3	-	28162770	P31FUJ	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.20032575184736112	[316]	[427]	2	hSpCas9	negative selection	10161004
81761476	81761499	3	+	28162770	P31FUJ	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.25833729652151605	[227]	[223]	-2	hSpCas9	negative selection	10161005
81705506	81705529	3	-	28162770	P31FUJ	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.053106667672001895	[145]	[177]	0	hSpCas9	negative selection	10161006
81648962	81648985	3	-	28162770	P31FUJ	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	-0.031168343244728128	[219]	[252]	0	hSpCas9	negative selection	10161007
81642918	81642941	3	+	28162770	P31FUJ	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.11684877142950145	[931]	[1009]	-1	hSpCas9	negative selection	10161008
81593908	81593931	3	-	28162770	P31FUJ	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.3432455714990299	[486]	[725]	4	hSpCas9	negative selection	10161009
81499186	81499209	3	-	28162770	P31FUJ	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.11250797069666682	[252]	[274]	-1	hSpCas9	negative selection	10161010
81535197	81535220	3	-	28162770	TF1	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10330367
81761434	81761457	3	+	28162770	TF1	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10330368
81761388	81761411	3	-	28162770	TF1	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	NaN	[NaN]	[214]	1	hSpCas9	negative selection	10330369
81499196	81499219	3	-	28162770	TF1	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10330370
81761476	81761499	3	+	28162770	TF1	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10330371
81705506	81705529	3	-	28162770	TF1	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10330372
81648962	81648985	3	-	28162770	TF1	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10330373
81642918	81642941	3	+	28162770	TF1	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	NaN	[NaN]	[802]	1	hSpCas9	negative selection	10330374
81593908	81593931	3	-	28162770	TF1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	NaN	[NaN]	[608]	1	hSpCas9	negative selection	10330375
81499186	81499209	3	-	28162770	TF1	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10330376
81535197	81535220	3	-	28162770	SKM1	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.8624964762500651	[13]	[44]	7	hSpCas9	negative selection	10499733
81761434	81761457	3	+	28162770	SKM1	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.27753397552890896	[34]	[74]	2	hSpCas9	negative selection	10499734
81761388	81761411	3	-	28162770	SKM1	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.12204189600397919	[91]	[176]	1	hSpCas9	negative selection	10499735
81499196	81499219	3	-	28162770	SKM1	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.3308497900613655	[84]	[188]	3	hSpCas9	negative selection	10499736
81761476	81761499	3	+	28162770	SKM1	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	1.424158889247392	[42]	[203]	9	hSpCas9	negative selection	10499737
81705506	81705529	3	-	28162770	SKM1	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10499738
81648962	81648985	3	-	28162770	SKM1	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.5461494136260023	[42]	[110]	5	hSpCas9	negative selection	10499739
81642918	81642941	3	+	28162770	SKM1	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.42987060152448797	[172]	[411]	4	hSpCas9	negative selection	10499740
81593908	81593931	3	-	28162770	SKM1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.7532128261475883	[98]	[294]	7	hSpCas9	negative selection	10499741
81499186	81499209	3	-	28162770	SKM1	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.5554867234532499	[68]	[82]	-4	hSpCas9	negative selection	10499742
81535197	81535220	3	-	28162770	SKM1	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.8624964762500651	[13]	[44]	7	hSpCas9	negative selection	10669099
81761434	81761457	3	+	28162770	SKM1	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.27753397552890896	[34]	[74]	2	hSpCas9	negative selection	10669100
81761388	81761411	3	-	28162770	SKM1	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.12204189600397919	[91]	[176]	1	hSpCas9	negative selection	10669101
81499196	81499219	3	-	28162770	SKM1	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.3308497900613655	[84]	[188]	3	hSpCas9	negative selection	10669102
81761476	81761499	3	+	28162770	SKM1	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	1.424158889247392	[42]	[203]	9	hSpCas9	negative selection	10669103
81705506	81705529	3	-	28162770	SKM1	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10669104
81648962	81648985	3	-	28162770	SKM1	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.5461494136260023	[42]	[110]	5	hSpCas9	negative selection	10669105
81642918	81642941	3	+	28162770	SKM1	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.42987060152448797	[172]	[411]	4	hSpCas9	negative selection	10669106
81593908	81593931	3	-	28162770	SKM1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.7532128261475883	[98]	[294]	7	hSpCas9	negative selection	10669107
81499186	81499209	3	-	28162770	SKM1	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.5554867234532499	[68]	[82]	-4	hSpCas9	negative selection	10669108
81535197	81535220	3	-	28162770	PL21	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.8807803808942474	[54]	[12]	-6	hSpCas9	negative selection	10838465
81761434	81761457	3	+	28162770	PL21	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.2547623456674632	[158]	[57]	-2	hSpCas9	negative selection	10838466
81761388	81761411	3	-	28162770	PL21	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.017017310665430774	[301]	[132]	0	hSpCas9	negative selection	10838467
81499196	81499219	3	-	28162770	PL21	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	-0.41457022962588824	[342]	[111]	-3	hSpCas9	negative selection	10838468
81761476	81761499	3	+	28162770	PL21	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.2792126982712372	[236]	[84]	-2	hSpCas9	negative selection	10838469
81705506	81705529	3	-	28162770	PL21	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.36269262727528	[108]	[60]	3	hSpCas9	negative selection	10838470
81648962	81648985	3	-	28162770	PL21	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.523836802229738	[162]	[101]	4	hSpCas9	negative selection	10838471
81642918	81642941	3	+	28162770	PL21	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.17047964096908053	[687]	[336]	1	hSpCas9	negative selection	10838472
81593908	81593931	3	-	28162770	PL21	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.3659718612977495	[352]	[197]	3	hSpCas9	negative selection	10838473
81499186	81499209	3	-	28162770	PL21	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	1.2253401686144627	[226]	[230]	8	hSpCas9	negative selection	10838474
81535197	81535220	3	-	28162770	P31FUJ	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.42544728235677454	[31]	[27]	-4	hSpCas9	negative selection	11007831
81761434	81761457	3	+	28162770	P31FUJ	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.8993784706891869	[199]	[125]	-6	hSpCas9	negative selection	11007832
81761388	81761411	3	-	28162770	P31FUJ	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.3251134205122208	[340]	[501]	3	hSpCas9	negative selection	11007833
81499196	81499219	3	-	28162770	P31FUJ	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.20032575184736112	[316]	[427]	2	hSpCas9	negative selection	11007834
81761476	81761499	3	+	28162770	P31FUJ	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.25833729652151605	[227]	[223]	-2	hSpCas9	negative selection	11007835
81705506	81705529	3	-	28162770	P31FUJ	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.053106667672001895	[145]	[177]	0	hSpCas9	negative selection	11007836
81648962	81648985	3	-	28162770	P31FUJ	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	-0.031168343244728128	[219]	[252]	0	hSpCas9	negative selection	11007837
81642918	81642941	3	+	28162770	P31FUJ	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.11684877142950145	[931]	[1009]	-1	hSpCas9	negative selection	11007838
81593908	81593931	3	-	28162770	P31FUJ	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.3432455714990299	[486]	[725]	4	hSpCas9	negative selection	11007839
81499186	81499209	3	-	28162770	P31FUJ	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.11250797069666682	[252]	[274]	-1	hSpCas9	negative selection	11007840
81535197	81535220	3	-	28162770	OCIAML5	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.3995543661664902	[18]	[25]	-3	hSpCas9	negative selection	11177197
81761434	81761457	3	+	28162770	OCIAML5	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.5751046840507021	[73]	[198]	5	hSpCas9	negative selection	11177198
81761388	81761411	3	-	28162770	OCIAML5	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.003543519800828232	[167]	[303]	0	hSpCas9	negative selection	11177199
81499196	81499219	3	-	28162770	OCIAML5	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.1284372535102058	[148]	[293]	1	hSpCas9	negative selection	11177200
81761476	81761499	3	+	28162770	OCIAML5	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-4.151626852722904	[127]	[12]	-9	hSpCas9	negative selection	11177201
81705506	81705529	3	-	28162770	OCIAML5	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.238421315438756	[82]	[126]	-2	hSpCas9	negative selection	11177202
81648962	81648985	3	-	28162770	OCIAML5	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.10212973952287815	[127]	[247]	0	hSpCas9	negative selection	11177203
81642918	81642941	3	+	28162770	OCIAML5	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.44091015032723635	[452]	[1109]	4	hSpCas9	negative selection	11177204
81593908	81593931	3	-	28162770	OCIAML5	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.05984209951114616	[286]	[539]	0	hSpCas9	negative selection	11177205
81499186	81499209	3	-	28162770	OCIAML5	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.6167773721106404	[124]	[345]	5	hSpCas9	negative selection	11177206
81535197	81535220	3	-	28162770	EOL1	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	1.1469401929069825	[53]	[62]	8	hSpCas9	negative selection	11346563
81761434	81761457	3	+	28162770	EOL1	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.652588135957257	[226]	[187]	6	hSpCas9	negative selection	11346564
81761388	81761411	3	-	28162770	EOL1	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	1.4048976608062487	[609]	[850]	9	hSpCas9	negative selection	11346565
81499196	81499219	3	-	28162770	EOL1	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.009664385208485338	[542]	[287]	0	hSpCas9	negative selection	11346566
81761476	81761499	3	+	28162770	EOL1	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.6672684001916842	[421]	[139]	-5	hSpCas9	negative selection	11346567
81705506	81705529	3	-	28162770	EOL1	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.6707911793247514	[216]	[181]	6	hSpCas9	negative selection	11346568
81648962	81648985	3	-	28162770	EOL1	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.6150644430498173	[201]	[162]	5	hSpCas9	negative selection	11346569
81642918	81642941	3	+	28162770	EOL1	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.2063742079895694	[838]	[509]	1	hSpCas9	negative selection	11346570
81593908	81593931	3	-	28162770	EOL1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.02985536198935501	[435]	[224]	0	hSpCas9	negative selection	11346571
81499186	81499209	3	-	28162770	EOL1	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.29241076371528535	[264]	[113]	-2	hSpCas9	negative selection	11346572
81535197	81535220	3	-	28162770	MOLM13	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.8731475362904886	[75]	[29]	-5	hSpCas9	negative selection	11515929
81761434	81761457	3	+	28162770	MOLM13	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-1.0440096569868542	[153]	[53]	-5	hSpCas9	negative selection	11515930
81761388	81761411	3	-	28162770	MOLM13	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.9040793958423791	[395]	[152]	-5	hSpCas9	negative selection	11515931
81499196	81499219	3	-	28162770	MOLM13	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.5838974895099311	[417]	[452]	4	hSpCas9	negative selection	11515932
81761476	81761499	3	+	28162770	MOLM13	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-2.6818577379601036	[354]	[39]	-8	hSpCas9	negative selection	11515933
81705506	81705529	3	-	28162770	MOLM13	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.6959354203613158	[176]	[78]	-4	hSpCas9	negative selection	11515934
81648962	81648985	3	-	28162770	MOLM13	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	-0.04823424284857945	[265]	[185]	0	hSpCas9	negative selection	11515935
81642918	81642941	3	+	28162770	MOLM13	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.18636350841983984	[852]	[541]	-1	hSpCas9	negative selection	11515936
81593908	81593931	3	-	28162770	MOLM13	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.4975145506538572	[722]	[737]	3	hSpCas9	negative selection	11515937
81499186	81499209	3	-	28162770	MOLM13	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.8110311342552927	[346]	[142]	-4	hSpCas9	negative selection	11515938
81535197	81535220	3	-	28162770	HEL	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.7593596115709884	[36]	[13]	-5	hSpCas9	negative selection	11685295
81761434	81761457	3	+	28162770	HEL	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.37970442616656297	[167]	[139]	3	hSpCas9	negative selection	11685296
81761388	81761411	3	-	28162770	HEL	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.44905770730543626	[397]	[347]	4	hSpCas9	negative selection	11685297
81499196	81499219	3	-	28162770	HEL	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.6570230580066044	[401]	[405]	5	hSpCas9	negative selection	11685298
81761476	81761499	3	+	28162770	HEL	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	0.6926640573320391	[283]	[293]	6	hSpCas9	negative selection	11685299
81705506	81705529	3	-	28162770	HEL	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.9578348934052938	[126]	[157]	8	hSpCas9	negative selection	11685300
81648962	81648985	3	-	28162770	HEL	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.044837275571702584	[223]	[147]	0	hSpCas9	negative selection	11685301
81642918	81642941	3	+	28162770	HEL	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.5043698642887231	[666]	[605]	4	hSpCas9	negative selection	11685302
81593908	81593931	3	-	28162770	HEL	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	-0.2089384210425418	[470]	[260]	-1	hSpCas9	negative selection	11685303
81499186	81499209	3	-	28162770	HEL	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.03031499834565593	[286]	[179]	0	hSpCas9	negative selection	11685304
81535197	81535220	3	-	28162770	MV411	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.6972404682222957	[40]	[55]	6	hSpCas9	negative selection	11854661
81761434	81761457	3	+	28162770	MV411	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.696853016630937	[126]	[65]	-5	hSpCas9	negative selection	11854662
81761388	81761411	3	-	28162770	MV411	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	-0.17055326588541608	[325]	[243]	-1	hSpCas9	negative selection	11854663
81499196	81499219	3	-	28162770	MV411	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.36540088813706517	[222]	[241]	3	hSpCas9	negative selection	11854664
81761476	81761499	3	+	28162770	MV411	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.3237191504133503	[207]	[139]	-2	hSpCas9	negative selection	11854665
81705506	81705529	3	-	28162770	MV411	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.22204773251844512	[125]	[90]	-2	hSpCas9	negative selection	11854666
81648962	81648985	3	-	28162770	MV411	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.6498750132819856	[114]	[151]	6	hSpCas9	negative selection	11854667
81642918	81642941	3	+	28162770	MV411	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.03140317900843015	[568]	[468]	0	hSpCas9	negative selection	11854668
81593908	81593931	3	-	28162770	MV411	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.16862316760594687	[394]	[373]	1	hSpCas9	negative selection	11854669
81499186	81499209	3	-	28162770	MV411	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.4943693064529301	[198]	[118]	-4	hSpCas9	negative selection	11854670
81535197	81535220	3	-	28162770	MONOMAC1	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.8029631529404464	[17]	[35]	7	hSpCas9	negative selection	12024027
81761434	81761457	3	+	28162770	MONOMAC1	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-0.44606439489946825	[81]	[68]	-4	hSpCas9	negative selection	12024028
81761388	81761411	3	-	28162770	MONOMAC1	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.704878153258257	[212]	[397]	6	hSpCas9	negative selection	12024029
81499196	81499219	3	-	28162770	MONOMAC1	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	-0.12378786502891503	[191]	[201]	-1	hSpCas9	negative selection	12024030
81761476	81761499	3	+	28162770	MONOMAC1	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.22618319271907003	[149]	[146]	-2	hSpCas9	negative selection	12024031
81705506	81705529	3	-	28162770	MONOMAC1	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.09841903646661765	[65]	[80]	1	hSpCas9	negative selection	12024032
81648962	81648985	3	-	28162770	MONOMAC1	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	-0.010623722828672244	[86]	[98]	0	hSpCas9	negative selection	12024033
81642918	81642941	3	+	28162770	MONOMAC1	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	0.10499169039010381	[437]	[539]	1	hSpCas9	negative selection	12024034
81593908	81593931	3	-	28162770	MONOMAC1	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.3635664480331977	[218]	[322]	3	hSpCas9	negative selection	12024035
81499186	81499209	3	-	28162770	MONOMAC1	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	-0.4175372090547931	[126]	[108]	-4	hSpCas9	negative selection	12024036
81535197	81535220	3	-	28162770	OCIAML2	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	0.22980989289893117	[5]	[38]	2	hSpCas9	negative selection	12193393
81761434	81761457	3	+	28162770	OCIAML2	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	0.6118323349498118	[16]	[143]	6	hSpCas9	negative selection	12193394
81761388	81761411	3	-	28162770	OCIAML2	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.27045187739627674	[69]	[467]	2	hSpCas9	negative selection	12193395
81499196	81499219	3	-	28162770	OCIAML2	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.2901825108784125	[53]	[365]	2	hSpCas9	negative selection	12193396
81761476	81761499	3	+	28162770	OCIAML2	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.855293675477486	[46]	[143]	-5	hSpCas9	negative selection	12193397
81705506	81705529	3	-	28162770	OCIAML2	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	0.15740139737088088	[21]	[135]	1	hSpCas9	negative selection	12193398
81648962	81648985	3	-	28162770	OCIAML2	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	-0.3122004626376782	[27]	[124]	-3	hSpCas9	negative selection	12193399
81642918	81642941	3	+	28162770	OCIAML2	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.5053952434028379	[125]	[491]	-4	hSpCas9	negative selection	12193400
81593908	81593931	3	-	28162770	OCIAML2	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.5977073045209923	[66]	[561]	6	hSpCas9	negative selection	12193401
81499186	81499209	3	-	28162770	OCIAML2	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.09179010682790661	[42]	[253]	0	hSpCas9	negative selection	12193402
81535197	81535220	3	-	28162770	OCIAML3	viability	GAGTTGGAACAGCATTGCCAGGG	GBE1	ENSG00000114480	-0.4684767582403042	[10]	[23]	-4	hSpCas9	negative selection	12362759
81761434	81761457	3	+	28162770	OCIAML3	viability	CAGTTCGGGCACGTCAGCCAGGG	GBE1	ENSG00000114480	-2.294447358465255	[38]	[23]	-9	hSpCas9	negative selection	12362760
81761388	81761411	3	-	28162770	OCIAML3	viability	GTACTTGAAGCCCTACGCCGTGG	GBE1	ENSG00000114480	0.17404563162613995	[100]	[343]	1	hSpCas9	negative selection	12362761
81499196	81499219	3	-	28162770	OCIAML3	viability	TGTGCTAGATTCAGATGCAGCGG	GBE1	ENSG00000114480	0.024121724332192174	[85]	[263]	0	hSpCas9	negative selection	12362762
81761476	81761499	3	+	28162770	OCIAML3	viability	GTAGTCCTCGGGCCGAGCCGCGG	GBE1	ENSG00000114480	-0.3286630738031683	[51]	[124]	-3	hSpCas9	negative selection	12362763
81705506	81705529	3	-	28162770	OCIAML3	viability	GGCGTCCACAGATGTGCTGATGG	GBE1	ENSG00000114480	-0.17505509104193612	[45]	[122]	-1	hSpCas9	negative selection	12362764
81648962	81648985	3	-	28162770	OCIAML3	viability	ATTCCAGACCAAAGAAGCCACGG	GBE1	ENSG00000114480	0.7708290460324901	[52]	[272]	7	hSpCas9	negative selection	12362765
81642918	81642941	3	+	28162770	OCIAML3	viability	TAAGAGGACTATGATACCCATGG	GBE1	ENSG00000114480	-0.16104823304805693	[189]	[512]	-1	hSpCas9	negative selection	12362766
81593908	81593931	3	-	28162770	OCIAML3	viability	GCTTTATCATCACCATGGAGTGG	GBE1	ENSG00000114480	0.45168445036870575	[100]	[416]	4	hSpCas9	negative selection	12362767
81499186	81499209	3	-	28162770	OCIAML3	viability	TCAGATGCAGCGGAATATGGAGG	GBE1	ENSG00000114480	0.8073549220576041	[52]	[279]	7	hSpCas9	negative selection	12362768