Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10220
• Symbol: GDF11
• Description: growth differentiation factor 11

DataSource: http://genomecrispr.dkfz.de/#!/results/GDF11

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
55743604	55743627	12	-	26472758	Jiyoye	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.5144693946777821	[271]	[292]	4	hSpCas9	negative selection	62518
55743726	55743749	12	-	26472758	Jiyoye	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	62519
55743688	55743711	12	+	26472758	Jiyoye	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.329790212660333	[239]	[35]	-8	hSpCas9	negative selection	62520
55743502	55743525	12	-	26472758	Jiyoye	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.928007544807314	[137]	[197]	6	hSpCas9	negative selection	62521
55743592	55743615	12	+	26472758	Jiyoye	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.476596782463353	[141]	[148]	3	hSpCas9	negative selection	62522
55743330	55743353	12	-	26472758	Jiyoye	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.9432282817460833	[29]	[86]	8	hSpCas9	negative selection	62523
55748650	55748673	12	+	26472758	Jiyoye	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.11055837514769852	[112]	[91]	0	hSpCas9	negative selection	62524
55748712	55748735	12	-	26472758	Jiyoye	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	-0.1492179670185118	[174]	[118]	-1	hSpCas9	negative selection	62525
55748734	55748757	12	+	26472758	Jiyoye	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.6702097873396673	[39]	[47]	5	hSpCas9	negative selection	62526
55743638	55743661	12	-	26472758	Jiyoye	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.29700027754266345	[144]	[88]	-2	hSpCas9	negative selection	62527
55743604	55743627	12	-	26472758	KBM7	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.32193427450604006	[1263,1189]	[987,484]	3	hSpCas9	negative selection	253636
55743726	55743749	12	-	26472758	KBM7	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	0.6149777150142448	[178,135]	[123,101]	6	hSpCas9	negative selection	253637
55743688	55743711	12	+	26472758	KBM7	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.6528201631328057	[1134,798]	[128,154]	-8	hSpCas9	negative selection	253638
55743502	55743525	12	-	26472758	KBM7	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.5033496529055417	[631,638]	[607,262]	5	hSpCas9	negative selection	253639
55743592	55743615	12	+	26472758	KBM7	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.16146894528920175	[839,515]	[338,358]	1	hSpCas9	negative selection	253640
55743330	55743353	12	-	26472758	KBM7	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.2670718016382994	[298,179]	[322,213]	9	hSpCas9	negative selection	253641
55748650	55748673	12	+	26472758	KBM7	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.03693291950691191	[717,730]	[341,359]	0	hSpCas9	negative selection	253642
55748712	55748735	12	-	26472758	KBM7	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.5576425833159528	[650,672]	[448,471]	6	hSpCas9	negative selection	253643
55748734	55748757	12	+	26472758	KBM7	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.7167401288196128	[358,289]	[86,96]	-5	hSpCas9	negative selection	253644
55743638	55743661	12	-	26472758	KBM7	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.6563010717363822	[554,533]	[173,152]	-5	hSpCas9	negative selection	253645
55743604	55743627	12	-	26472758	Raji	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.3925947320520682	[580]	[176]	4	hSpCas9	negative selection	444754
55743726	55743749	12	-	26472758	Raji	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.4925293068135281	[96]	[7]	-8	hSpCas9	negative selection	444755
55743688	55743711	12	+	26472758	Raji	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.4721038352814055	[525]	[21]	-9	hSpCas9	negative selection	444756
55743502	55743525	12	-	26472758	Raji	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.922958964236172	[174]	[76]	8	hSpCas9	negative selection	444757
55743592	55743615	12	+	26472758	Raji	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.25189797399613256	[312]	[60]	-2	hSpCas9	negative selection	444758
55743330	55743353	12	-	26472758	Raji	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.8882150149114378	[148]	[63]	7	hSpCas9	negative selection	444759
55748650	55748673	12	+	26472758	Raji	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.29776556180742636	[318]	[90]	3	hSpCas9	negative selection	444760
55748712	55748735	12	-	26472758	Raji	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.18301797321045066	[352]	[92]	1	hSpCas9	negative selection	444761
55748734	55748757	12	+	26472758	Raji	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.6452777824379766	[134]	[48]	6	hSpCas9	negative selection	444762
55743638	55743661	12	-	26472758	Raji	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.8966183951838967	[360]	[44]	-6	hSpCas9	negative selection	444763
55743604	55743627	12	-	26472758	K562	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.009181861006359426	[1066]	[894]	0	hSpCas9	negative selection	635872
55743726	55743749	12	-	26472758	K562	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-5.562936194391156	[55]	[0]	-9	hSpCas9	negative selection	635873
55743688	55743711	12	+	26472758	K562	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.7767804380393857	[616]	[75]	-8	hSpCas9	negative selection	635874
55743502	55743525	12	-	26472758	K562	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.9009753121242846	[379]	[598]	7	hSpCas9	negative selection	635875
55743592	55743615	12	+	26472758	K562	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.10442565189081399	[637]	[578]	0	hSpCas9	negative selection	635876
55743330	55743353	12	-	26472758	K562	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.5305756915319875	[195]	[238]	4	hSpCas9	negative selection	635877
55748650	55748673	12	+	26472758	K562	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.4860298817719695	[588]	[354]	-3	hSpCas9	negative selection	635878
55748712	55748735	12	-	26472758	K562	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	-0.1892344497797438	[415]	[307]	-1	hSpCas9	negative selection	635879
55748734	55748757	12	+	26472758	K562	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.680813503931581	[187]	[98]	-4	hSpCas9	negative selection	635880
55743638	55743661	12	-	26472758	K562	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-1.1799659438716497	[670]	[249]	-6	hSpCas9	negative selection	635881
55743502	55743525	12	-	26627737	DLD1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.2028248940792996	[136]	[8,121,23]	2	hSpCas9	negative selection	784630
55743721	55743744	12	-	26627737	DLD1	viability	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.1763136638255799	[834]	[256,493,162]	1	hSpCas9	negative selection	784631
55748674	55748697	12	-	26627737	DLD1	viability	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.7042399180233919	[521]	[310,308,190]	7	hSpCas9	negative selection	784632
55748926	55748949	12	+	26627737	DLD1	viability	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.12594057883412546	[1123]	[419,350,212]	-1	hSpCas9	negative selection	784633
55749546	55749569	12	-	26627737	DLD1	viability	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	1.0981652537355195	[343]	[221,389,104]	8	hSpCas9	negative selection	784634
55749687	55749710	12	-	26627737	DLD1	viability	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.7526397373718838	[320]	[248,105,151]	7	hSpCas9	negative selection	784635
55743502	55743525	12	-	26627737	GBM cells	viability after 5 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.09885144539443758	[73]	[39,44]	1	hSpCas9	negative selection	866945
55743721	55743744	12	-	26627737	GBM cells	viability after 5 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.44461694515961475	[297]	[199,234]	6	hSpCas9	negative selection	866946
55748674	55748697	12	-	26627737	GBM cells	viability after 5 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.1489847478690841	[353]	[186,233]	2	hSpCas9	negative selection	866947
55748926	55748949	12	+	26627737	GBM cells	viability after 5 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.05625041263377639	[485]	[274,266]	0	hSpCas9	negative selection	866948
55749546	55749569	12	-	26627737	GBM cells	viability after 5 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.8238578376977661	[235]	[63,78]	-8	hSpCas9	negative selection	866949
55749687	55749710	12	-	26627737	GBM cells	viability after 5 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.6530036468431011	[66]	[43,68]	8	hSpCas9	negative selection	866950
55743502	55743525	12	-	26627737	GBM cells	viability after 13 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.22406243363848022	[73]	[24,41]	-3	hSpCas9	negative selection	949260
55743721	55743744	12	-	26627737	GBM cells	viability after 13 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.7354613216499788	[297]	[325,222]	8	hSpCas9	negative selection	949261
55748674	55748697	12	-	26627737	GBM cells	viability after 13 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.5379723717395908	[353]	[306,255]	6	hSpCas9	negative selection	949262
55748926	55748949	12	+	26627737	GBM cells	viability after 13 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.23256307508594243	[485]	[267,188]	-3	hSpCas9	negative selection	949263
55749546	55749569	12	-	26627737	GBM cells	viability after 13 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.5820671903295459	[235]	[127,50]	-6	hSpCas9	negative selection	949264
55749687	55749710	12	-	26627737	GBM cells	viability after 13 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.5060119045401206	[66]	[60,43]	6	hSpCas9	negative selection	949265
55743502	55743525	12	-	26627737	GBM cells	viability after 21 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.6609784666909464	[73]	[61,64]	6	hSpCas9	negative selection	1031575
55743721	55743744	12	-	26627737	GBM cells	viability after 21 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.49872775003035646	[297]	[210,244]	5	hSpCas9	negative selection	1031576
55748674	55748697	12	-	26627737	GBM cells	viability after 21 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.8466999181758419	[353]	[348,342]	8	hSpCas9	negative selection	1031577
55748926	55748949	12	+	26627737	GBM cells	viability after 21 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.4119070645747396	[485]	[222,175]	-4	hSpCas9	negative selection	1031578
55749546	55749569	12	-	26627737	GBM cells	viability after 21 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-1.286333400564191	[235]	[50,53]	-8	hSpCas9	negative selection	1031579
55749687	55749710	12	-	26627737	GBM cells	viability after 21 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.4878261542061353	[66]	[49,51]	5	hSpCas9	negative selection	1031580
55743502	55743525	12	-	26627737	RPE1	viability after 9 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.13677563925148162	[229]	[61,69]	-1	hSpCas9	negative selection	1113890
55743721	55743744	12	-	26627737	RPE1	viability after 9 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	-0.05227039418186985	[1459]	[318,597]	0	hSpCas9	negative selection	1113891
55748674	55748697	12	-	26627737	RPE1	viability after 9 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.3723928437918356	[946]	[149,330]	-3	hSpCas9	negative selection	1113892
55748926	55748949	12	+	26627737	RPE1	viability after 9 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.8625635362375682	[2428]	[281,593]	-6	hSpCas9	negative selection	1113893
55749546	55749569	12	-	26627737	RPE1	viability after 9 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	8.402791785837552	[0]	[115,92]	9	hSpCas9	negative selection	1113894
55749687	55749710	12	-	26627737	RPE1	viability after 9 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.9710688626488928	[320]	[134,276]	6	hSpCas9	negative selection	1113895
55743502	55743525	12	-	26627737	RPE1	viability after 12 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.43390406369994694	[229]	[53,36]	-3	hSpCas9	negative selection	1196205
55743721	55743744	12	-	26627737	RPE1	viability after 12 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.37182580917937647	[1459]	[526,486]	2	hSpCas9	negative selection	1196206
55748674	55748697	12	-	26627737	RPE1	viability after 12 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.0994122818360019	[946]	[202,273]	0	hSpCas9	negative selection	1196207
55748926	55748949	12	+	26627737	RPE1	viability after 12 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.8347860852822497	[2428]	[327,405]	-5	hSpCas9	negative selection	1196208
55749546	55749569	12	-	26627737	RPE1	viability after 12 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	8.649089323827976	[0]	[102,112]	9	hSpCas9	negative selection	1196209
55749687	55749710	12	-	26627737	RPE1	viability after 12 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.8230229341807846	[320]	[120,185]	5	hSpCas9	negative selection	1196210
55743502	55743525	12	-	26627737	RPE1	viability after 15 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.3390798112340476	[229]	[26,74]	-2	hSpCas9	negative selection	1278520
55743721	55743744	12	-	26627737	RPE1	viability after 15 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.7952427136959725	[1459]	[732,700]	5	hSpCas9	negative selection	1278521
55748674	55748697	12	-	26627737	RPE1	viability after 15 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.11895486954945073	[946]	[295,285]	0	hSpCas9	negative selection	1278522
55748926	55748949	12	+	26627737	RPE1	viability after 15 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-1.5095866491539809	[2428]	[166,312]	-7	hSpCas9	negative selection	1278523
55749546	55749569	12	-	26627737	RPE1	viability after 15 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	8.619513084212866	[0]	[152,70]	9	hSpCas9	negative selection	1278524
55749687	55749710	12	-	26627737	RPE1	viability after 15 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	1.7857553000282589	[320]	[82,534]	8	hSpCas9	negative selection	1278525
55743502	55743525	12	-	26627737	RPE1	viability after 18 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.03126254714210752	[229]	[23,99]	0	hSpCas9	negative selection	1360835
55743721	55743744	12	-	26627737	RPE1	viability after 18 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.31674264796019314	[1459]	[526,451]	2	hSpCas9	negative selection	1360836
55748674	55748697	12	-	26627737	RPE1	viability after 18 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.11401145013494673	[946]	[152,324]	0	hSpCas9	negative selection	1360837
55748926	55748949	12	+	26627737	RPE1	viability after 18 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.6124896403126756	[2428]	[333,529]	-4	hSpCas9	negative selection	1360838
55749546	55749569	12	-	26627737	RPE1	viability after 18 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	9.095606240113852	[0]	[209,80]	9	hSpCas9	negative selection	1360839
55749687	55749710	12	-	26627737	RPE1	viability after 18 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.9245381476990616	[320]	[103,228]	5	hSpCas9	negative selection	1360840
55743502	55743525	12	-	26627737	HeLa	viability after 8 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.7701641541610829	[112]	[34,94,108]	6	hSpCas9	negative selection	1443150
55743721	55743744	12	-	26627737	HeLa	viability after 8 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	-0.5203738705510199	[752]	[324,203,180]	-5	hSpCas9	negative selection	1443151
55748674	55748697	12	-	26627737	HeLa	viability after 8 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.0022468544921174782	[780]	[408,342,287]	0	hSpCas9	negative selection	1443152
55748926	55748949	12	+	26627737	HeLa	viability after 8 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.043384274014344526	[791]	[306,485,212]	0	hSpCas9	negative selection	1443153
55749546	55749569	12	-	26627737	HeLa	viability after 8 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-4.10828187611163	[520]	[26,9,5]	-9	hSpCas9	negative selection	1443154
55749687	55749710	12	-	26627737	HeLa	viability after 8 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.6186874372864041	[230]	[223,79,172]	5	hSpCas9	negative selection	1443155
55743502	55743525	12	-	26627737	HeLa	viability after 12 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.3019143084713709	[112]	[98,18,59]	2	hSpCas9	negative selection	1525465
55743721	55743744	12	-	26627737	HeLa	viability after 12 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	-0.04917548246876213	[752]	[208,315,372]	0	hSpCas9	negative selection	1525466
55748674	55748697	12	-	26627737	HeLa	viability after 12 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.3446253196127991	[780]	[264,563,379]	3	hSpCas9	negative selection	1525467
55748926	55748949	12	+	26627737	HeLa	viability after 12 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.10308851950972087	[791]	[451,280,187]	-1	hSpCas9	negative selection	1525468
55749546	55749569	12	-	26627737	HeLa	viability after 12 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-2.1533381612583793	[520]	[6,104,25]	-9	hSpCas9	negative selection	1525469
55749687	55749710	12	-	26627737	HeLa	viability after 12 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	1.209449064467619	[230]	[282,164,221]	8	hSpCas9	negative selection	1525470
55743502	55743525	12	-	26627737	HeLa	viability after 15 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.3732488415938049	[112]	[29,54,96]	3	hSpCas9	negative selection	1607780
55743721	55743744	12	-	26627737	HeLa	viability after 15 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.051031341528512075	[752]	[283,208,471]	0	hSpCas9	negative selection	1607781
55748674	55748697	12	-	26627737	HeLa	viability after 15 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.5191403654346762	[780]	[351,539,477]	4	hSpCas9	negative selection	1607782
55748926	55748949	12	+	26627737	HeLa	viability after 15 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.35440976242022804	[791]	[297,229,225]	-3	hSpCas9	negative selection	1607783
55749546	55749569	12	-	26627737	HeLa	viability after 15 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.23993020820240532	[520]	[155,216,164]	-2	hSpCas9	negative selection	1607784
55749687	55749710	12	-	26627737	HeLa	viability after 15 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.8150328757932459	[230]	[27,124,359]	6	hSpCas9	negative selection	1607785
55743502	55743525	12	-	26627737	HeLa	viability after 18 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.45123688261035566	[112]	[22,49,96]	4	hSpCas9	negative selection	1690095
55743721	55743744	12	-	26627737	HeLa	viability after 18 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.044944877930181426	[752]	[179,182,471]	0	hSpCas9	negative selection	1690096
55748674	55748697	12	-	26627737	HeLa	viability after 18 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.5309942251998045	[780]	[245,443,477]	4	hSpCas9	negative selection	1690097
55748926	55748949	12	+	26627737	HeLa	viability after 18 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.33892140181122166	[791]	[203,191,225]	-3	hSpCas9	negative selection	1690098
55749546	55749569	12	-	26627737	HeLa	viability after 18 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.25327319921182634	[520]	[97,183,164]	-2	hSpCas9	negative selection	1690099
55749687	55749710	12	-	26627737	HeLa	viability after 18 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.7769243913719945	[230]	[17,93,359]	6	hSpCas9	negative selection	1690100
55743502	55743525	12	-	26627737	HCT116	viability after 6 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-1.6595215087408572	[45]	[0,2]	-7	hSpCas9	negative selection	1772410
55743721	55743744	12	-	26627737	HCT116	viability after 6 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.5944120049305439	[1239]	[196,347]	3	hSpCas9	negative selection	1772411
55748674	55748697	12	-	26627737	HCT116	viability after 6 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.5717994411955267	[1383]	[334,316]	3	hSpCas9	negative selection	1772412
55748926	55748949	12	+	26627737	HCT116	viability after 6 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.6001547609975824	[1431]	[406,304]	3	hSpCas9	negative selection	1772413
55749546	55749569	12	-	26627737	HCT116	viability after 6 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.06834440033466138	[477]	[197,1]	0	hSpCas9	negative selection	1772414
55749687	55749710	12	-	26627737	HCT116	viability after 6 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.3994916532158379	[482]	[94,102]	2	hSpCas9	negative selection	1772415
55743502	55743525	12	-	26627737	HCT116	viability after 8 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.008536153949443959	[101]	[74,42,51]	0	hSpCas9	negative selection	1854725
55743721	55743744	12	-	26627737	HCT116	viability after 8 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.6271957293334187	[460]	[511,340,326]	6	hSpCas9	negative selection	1854726
55748674	55748697	12	-	26627737	HCT116	viability after 8 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.09012676324400304	[624]	[354,330,412]	1	hSpCas9	negative selection	1854727
55748926	55748949	12	+	26627737	HCT116	viability after 8 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.30163886666601236	[772]	[315,356,362]	-4	hSpCas9	negative selection	1854728
55749546	55749569	12	-	26627737	HCT116	viability after 8 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	0.6588204498609702	[168]	[168,169,102]	6	hSpCas9	negative selection	1854729
55749687	55749710	12	-	26627737	HCT116	viability after 8 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.020025960659506903	[414]	[163,246,263]	0	hSpCas9	negative selection	1854730
55743502	55743525	12	-	26627737	HCT116	viability after 9 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	3.295880329158023	[45]	[271,0]	9	hSpCas9	negative selection	1937040
55743721	55743744	12	-	26627737	HCT116	viability after 9 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.12713065102725274	[1239]	[331,384]	1	hSpCas9	negative selection	1937041
55748674	55748697	12	-	26627737	HCT116	viability after 9 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.007072599854495598	[1383]	[467,294]	0	hSpCas9	negative selection	1937042
55748926	55748949	12	+	26627737	HCT116	viability after 9 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.017095088155526073	[1431]	[420,359]	0	hSpCas9	negative selection	1937043
55749546	55749569	12	-	26627737	HCT116	viability after 9 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	1.2106314196131822	[477]	[572,75]	7	hSpCas9	negative selection	1937044
55749687	55749710	12	-	26627737	HCT116	viability after 9 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.7335079115482044	[482]	[33,111]	-5	hSpCas9	negative selection	1937045
55743502	55743525	12	-	26627737	HCT116	viability after 12 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.4714097459249582	[101]	[68,97,56]	4	hSpCas9	negative selection	2019355
55743721	55743744	12	-	26627737	HCT116	viability after 12 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.6125203340927037	[460]	[426,400,278]	6	hSpCas9	negative selection	2019356
55748674	55748697	12	-	26627737	HCT116	viability after 12 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.3082756215352557	[624]	[234,246,315]	-3	hSpCas9	negative selection	2019357
55748926	55748949	12	+	26627737	HCT116	viability after 12 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.03453402930313776	[772]	[387,246,551]	0	hSpCas9	negative selection	2019358
55749546	55749569	12	-	26627737	HCT116	viability after 12 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	0.9145670284719716	[168]	[230,98,164]	7	hSpCas9	negative selection	2019359
55749687	55749710	12	-	26627737	HCT116	viability after 12 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.05509659918354137	[414]	[165,307,161]	0	hSpCas9	negative selection	2019360
55743502	55743525	12	-	26627737	HCT116	viability after 15 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.9013450229762865	[101]	[97,131,96]	7	hSpCas9	negative selection	2101670
55743721	55743744	12	-	26627737	HCT116	viability after 15 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.3528575573914948	[460]	[185,486,322]	3	hSpCas9	negative selection	2101671
55748674	55748697	12	-	26627737	HCT116	viability after 15 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.5614510509054619	[624]	[261,313,156]	-5	hSpCas9	negative selection	2101672
55748926	55748949	12	+	26627737	HCT116	viability after 15 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.08525830573546034	[772]	[441,384,580]	0	hSpCas9	negative selection	2101673
55749546	55749569	12	-	26627737	HCT116	viability after 15 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	0.1927253614996144	[168]	[144,86,104]	2	hSpCas9	negative selection	2101674
55749687	55749710	12	-	26627737	HCT116	viability after 15 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.14207384266057482	[414]	[138,462,172]	1	hSpCas9	negative selection	2101675
55743502	55743525	12	-	26627737	HCT116	viability after 18 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.6789104017062965	[101]	[112,54,69]	5	hSpCas9	negative selection	2183985
55743721	55743744	12	-	26627737	HCT116	viability after 18 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.5331713181887299	[460]	[214,242,523]	4	hSpCas9	negative selection	2183986
55748674	55748697	12	-	26627737	HCT116	viability after 18 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.17307430012801717	[624]	[168,359,268]	-1	hSpCas9	negative selection	2183987
55748926	55748949	12	+	26627737	HCT116	viability after 18 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.47523453755636447	[772]	[576,234,776]	4	hSpCas9	negative selection	2183988
55749546	55749569	12	-	26627737	HCT116	viability after 18 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.2732784897674885	[168]	[75,53,73]	-3	hSpCas9	negative selection	2183989
55749687	55749710	12	-	26627737	HCT116	viability after 18 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.29869781330246703	[414]	[147,214,120]	-3	hSpCas9	negative selection	2183990
55743604	55743627	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.3136116788875203	[2,2]	[3,2]	6	hSpCas9	positive selection	2990301
55743502	55743525	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.9420392550881888	[2,3]	[1,0]	-9	hSpCas9	positive selection	2990302
55743383	55743406	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	-1.001918791979476	[1,2]	[0,0]	-9	hSpCas9	positive selection	2990303
55743477	55743500	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	-0.9917911573419207	[2,2]	[1,0]	-9	hSpCas9	positive selection	2990304
55743604	55743627	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.46571096643352233	[2,2]	[1,0]	-6	hSpCas9	positive selection	3058159
55743502	55743525	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.40185549063362613	[2,2]	[1,0]	-6	hSpCas9	positive selection	3058160
55743383	55743406	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	-0.1835092310273988	[1,1]	[2,0]	-3	hSpCas9	positive selection	3058161
55743477	55743500	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	-0.6642049297787174	[2,2]	[1,0]	-8	hSpCas9	positive selection	3058162
55743730	55743753		+	24336571	A375	resistance to PLX after 7 days	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.12737169126139697	[14,14]	[14,11]	-4	hSpCas9	positive selection	3116267
55749648	55749671		+	24336571	A375	resistance to PLX after 7 days	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.2564003456779974	[9,11]	[13,11]	7	hSpCas9	positive selection	3116268
55743589	55743612		+	24336571	A375	resistance to PLX after 7 days	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	0.37938903359290543	[7,9]	[12,9]	8	hSpCas9	positive selection	3116269
55749655	55749678		-	24336571	A375	resistance to PLX after 7 days	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.07127726402577653	[13,16]	[14,13]	-2	hSpCas9	positive selection	3116270
55743730	55743753		+	24336571	A375	resistance to PLX after 14 days	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.8523298240161374	[12,13]	[2,2]	-8	hSpCas9	positive selection	3174060
55749648	55749671		+	24336571	A375	resistance to PLX after 14 days	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.4000343590410499	[11,10]	[4,2]	-5	hSpCas9	positive selection	3174061
55743589	55743612		+	24336571	A375	resistance to PLX after 14 days	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	0.013112678875712436	[9,6]	[3,2]	0	hSpCas9	positive selection	3174062
55749655	55749678		-	24336571	A375	resistance to PLX after 14 days	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-1.0347614261613893	[12,23]	[3,2]	-9	hSpCas9	positive selection	3174063
55743730	55743753		+	24336571	A375	viability after 7 days	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.21617077042938074	[17]	[14,14]	-3	hSpCas9	negative selection	3231853
55749648	55749671		+	24336571	A375	viability after 7 days	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.22154927967186866	[13]	[9,11]	-3	hSpCas9	negative selection	3231854
55743589	55743612		+	24336571	A375	viability after 7 days	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	-0.6764554804735587	[14]	[7,9]	-7	hSpCas9	negative selection	3231855
55749655	55749678		-	24336571	A375	viability after 7 days	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.2417053011320342	[18]	[13,16]	-3	hSpCas9	negative selection	3231856
55743730	55743753		+	24336571	A375	viability after 14 days	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.320787330821369	[17]	[12,13]	-4	hSpCas9	negative selection	3289646
55749648	55749671		+	24336571	A375	viability after 14 days	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.08115892458466487	[13]	[11,10]	-1	hSpCas9	negative selection	3289647
55743589	55743612		+	24336571	A375	viability after 14 days	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	-0.7172691396022262	[14]	[9,6]	-7	hSpCas9	negative selection	3289648
55749655	55749678		-	24336571	A375	viability after 14 days	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.03575512086649624	[18]	[12,23]	0	hSpCas9	negative selection	3289649
55749655	55749678	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	1.202965739133528	[59,72]	[0,0]	5	hSpCas9	positive selection	3351262
55749648	55749671	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.22433515453463215	[124,136]	[0,0]	1	hSpCas9	positive selection	3351263
55748732	55748755	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.7566990956432155	[97,82]	[0,0]	3	hSpCas9	positive selection	3351264
55743495	55743518	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	2.808865710629541	[130,130]	[5,5]	8	hSpCas9	positive selection	3370472
55743504	55743527	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3370473
55748650	55748673	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.274055249070477	[184,184]	[0,0]	-2	hSpCas9	positive selection	3370474
55743604	55743627	12	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.350015024528271	[]	[]	-5	hSpCas9	negative selection	3427438
55743502	55743525	12	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.220270138346638	[]	[]	0	hSpCas9	negative selection	3427439
55743382	55743405	12	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	2.66355499016726	[]	[]	8	hSpCas9	negative selection	3427440
55743476	55743499	12	+	26780180	HT29	viability (Avana library 4 designs)	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	1.17084568344699	[]	[]	4	hSpCas9	negative selection	3427441
55743604	55743627	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	6.90703301960598	[]	[]	9	hSpCas9	negative selection	3511049
55743502	55743525	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	4.12004250517816	[]	[]	6	hSpCas9	negative selection	3511050
55743382	55743405	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	-2.8050585633341	[]	[]	-3	hSpCas9	negative selection	3511051
55743476	55743499	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	6.84694133613504	[]	[]	9	hSpCas9	negative selection	3511052
55743688	55743711	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-6.68223893479834	[]	[]	-6	hSpCas9	negative selection	3511053
55743498	55743521	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCCCGTGTGCGTTTGGCGG	GDF11	ENSG00000135414	4.49028165575381	[]	[]	7	hSpCas9	negative selection	3511054
55743604	55743627	12	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.262447647351126	[]	[]	0	hSpCas9	negative selection	3619708
55743502	55743525	12	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	1.83295889293557	[]	[]	2	hSpCas9	negative selection	3619709
55743382	55743405	12	+	26780180	A375	viability (Avana lentiGuide)	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	23.4854997952521	[]	[]	9	hSpCas9	negative selection	3619710
55743476	55743499	12	+	26780180	A375	viability (Avana lentiGuide)	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	0.870653077256666	[]	[]	1	hSpCas9	negative selection	3619711
55743688	55743711	12	+	26780180	A375	viability (Avana lentiGuide)	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	28.243065037268	[]	[]	9	hSpCas9	negative selection	3619712
55743498	55743521	12	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCCCGTGTGCGTTTGGCGG	GDF11	ENSG00000135414	6.84266416178075	[]	[]	5	hSpCas9	negative selection	3619713
55743604	55743627	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.3154458967206914	[4]	[5,4]	8	hSpCas9	positive selection	3728367
55743502	55743525	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.1588309916794709	[4]	[5,3]	4	hSpCas9	positive selection	3728368
55743382	55743405	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	-0.26208269214563457	[4]	[4,2]	-4	hSpCas9	positive selection	3728369
55743476	55743499	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	0.2931624114658976	[3]	[5,4]	8	hSpCas9	positive selection	3728370
55743688	55743711	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-0.99592102288781	[4]	[2,0]	-8	hSpCas9	positive selection	3728371
55743498	55743521	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCCCGTGTGCGTTTGGCGG	GDF11	ENSG00000135414	0.17693001771527425	[5]	[6,6]	5	hSpCas9	positive selection	3728372
55743604	55743627	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.5755744352176211	[4]	[2,2]	-6	hSpCas9	positive selection	3836974
55743502	55743525	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.008737005379304719	[4]	[4,3]	0	hSpCas9	positive selection	3836975
55743382	55743405	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGCGGCCGAGGGCCCCGCGG	GDF11	ENSG00000135414	-1.383340273104148	[4]	[0,1]	-9	hSpCas9	positive selection	3836976
55743476	55743499	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCGTGGCGCCCGAGCCGGACGG	GDF11	ENSG00000135414	-0.0855131591141643	[4]	[3,4]	-1	hSpCas9	positive selection	3836977
55743688	55743711	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.3218253645069113	[4]	[0,0]	-9	hSpCas9	positive selection	3836978
55743498	55743521	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCCCGTGTGCGTTTGGCGG	GDF11	ENSG00000135414	0.05485677616450868	[6]	[4,6]	1	hSpCas9	positive selection	3836979
55743495	55743518	12	+	26780180	A375	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.803706876276525	[]	[]	3	hSpCas9	negative selection	3943389
55749648	55749671	12	+	26780180	A375	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.978425898312845	[]	[]	4	hSpCas9	negative selection	3943390
55748650	55748673	12	+	26780180	A375	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	1.09646277718937	[]	[]	5	hSpCas9	negative selection	3943391
55743504	55743527	12	-	26780180	A375	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.980914006613715	[]	[]	4	hSpCas9	negative selection	3943392
55749655	55749678	12	-	26780180	A375	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	1.74090450483689	[]	[]	9	hSpCas9	negative selection	3943393
55748732	55748755	12	+	26780180	A375	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.623397573791143	[]	[]	2	hSpCas9	negative selection	3943394
55743495	55743518	12	+	26780180	HT29	viability (GeCKOv2 library)	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	1.47471814798665	[]	[]	7	hSpCas9	negative selection	4051355
55749648	55749671	12	+	26780180	HT29	viability (GeCKOv2 library)	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	1.69429854480125	[]	[]	8	hSpCas9	negative selection	4051356
55748650	55748673	12	+	26780180	HT29	viability (GeCKOv2 library)	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.650279804643633	[]	[]	2	hSpCas9	negative selection	4051357
55743504	55743527	12	-	26780180	HT29	viability (GeCKOv2 library)	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	1.16405308037629	[]	[]	5	hSpCas9	negative selection	4051358
55749655	55749678	12	-	26780180	HT29	viability (GeCKOv2 library)	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	2.55230908996126	[]	[]	9	hSpCas9	negative selection	4051359
55748732	55748755	12	+	26780180	HT29	viability (GeCKOv2 library)	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	1.86505315325133	[]	[]	8	hSpCas9	negative selection	4051360
55743730	55743753	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.3979529402682633	[3]	[1,1]	-7	hSpCas9	positive selection	4139442
55749648	55749671	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.2796681890947885	[3]	[1,1]	-6	hSpCas9	positive selection	4139443
55743589	55743612	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	-0.018890383150409418	[3]	[2,1]	0	hSpCas9	positive selection	4139444
55749655	55749678	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.14838965085485475	[4]	[2,1]	-3	hSpCas9	positive selection	4139445
55743730	55743753	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCGAGACCGTCATTAGCATGG	GDF11	ENSG00000135414	-0.5960926522317863	[3]	[0,0,0,0]	-7	hSpCas9	positive selection	4203464
55749648	55749671	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.963642595436027	[4]	[2,3,1,3]	6	hSpCas9	positive selection	4203465
55743589	55743612	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGCCCAACATCAGCCGCGAGG	GDF11	ENSG00000135414	1.3353453163141387	[1]	[0,1,1,2]	9	hSpCas9	positive selection	4203466
55749655	55749678	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.19321687319895936	[3]	[3,0,0,0]	-3	hSpCas9	positive selection	4203467
55749655	55749678	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-1.152737599844759	[2]	[0,0]	-9	hSpCas9	positive selection	4272542
55749648	55749671	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.30226986564115965	[2]	[2,2]	6	hSpCas9	positive selection	4272543
55748732	55748755	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.37562253187063055	[2]	[2,3]	7	hSpCas9	positive selection	4272544
55743495	55743518	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.22812838368659602	[2]	[3,1]	4	hSpCas9	positive selection	4336806
55743504	55743527	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.03582229568810566	[2]	[2,1]	0	hSpCas9	positive selection	4336807
55748650	55748673	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2618029517846389	[3]	[3,1]	-5	hSpCas9	positive selection	4336808
55743502	55743524	12	-	27760321	OCIAML3	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.06580623194226531	[815,688]	[532,718]	0	hSpCas9	negative selection	4403283
55743729	55743751	12	-	27760321	OCIAML3	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.036375281304165064	[590,551]	[353,542]	0	hSpCas9	negative selection	4403284
55748673	55748695	12	-	27760321	OCIAML3	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.6311695865450114	[657,539]	[669,789]	7	hSpCas9	negative selection	4403285
55748748	55748770	12	+	27760321	OCIAML3	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.30209361879933716	[577,448]	[243,426]	-3	hSpCas9	negative selection	4403286
55748803	55748825	12	-	27760321	OCIAML3	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.41212583719151397	[612,499]	[435,758]	5	hSpCas9	negative selection	4403287
55743502	55743524	12	-	27760321	OCIAML2	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.0349644427387833	[815,688]	[528,674]	0	hSpCas9	negative selection	4486746
55743729	55743751	12	-	27760321	OCIAML2	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.2359793279155012	[590,551]	[498,604]	3	hSpCas9	negative selection	4486747
55748673	55748695	12	-	27760321	OCIAML2	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.1434002586878459	[657,539]	[501,572]	1	hSpCas9	negative selection	4486748
55748748	55748770	12	+	27760321	OCIAML2	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.1221384775467496	[577,448]	[378,378]	-1	hSpCas9	negative selection	4486749
55748803	55748825	12	-	27760321	OCIAML2	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.17322642767482777	[612,499]	[454,570]	2	hSpCas9	negative selection	4486750
55743502	55743524	12	-	27760321	MV411	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.19833837894380302	[815,688]	[667,416]	1	hSpCas9	negative selection	4570209
55743729	55743751	12	-	27760321	MV411	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.43956337221892866	[590,551]	[165,1030]	3	hSpCas9	negative selection	4570210
55748673	55748695	12	-	27760321	MV411	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.42640637734540743	[657,539]	[359,781]	3	hSpCas9	negative selection	4570211
55748748	55748770	12	+	27760321	MV411	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.7976039910778454	[577,448]	[165,234]	-5	hSpCas9	negative selection	4570212
55748803	55748825	12	-	27760321	MV411	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.5956766599948593	[612,499]	[498,631]	4	hSpCas9	negative selection	4570213
55743502	55743524	12	-	27760321	HL60	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.10152898911642849	[815,688]	[548,593]	-1	hSpCas9	negative selection	4653672
55743729	55743751	12	-	27760321	HL60	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.7131460823048723	[590,551]	[198,375]	-6	hSpCas9	negative selection	4653673
55748673	55748695	12	-	27760321	HL60	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.30539780669254024	[657,539]	[593,609]	4	hSpCas9	negative selection	4653674
55748748	55748770	12	+	27760321	HL60	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.2082577160426222	[577,448]	[344,376]	-2	hSpCas9	negative selection	4653675
55748803	55748825	12	-	27760321	HL60	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.6343652643946142	[612,499]	[770,628]	7	hSpCas9	negative selection	4653676
55743502	55743524	12	-	27760321	HT1080	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.6243546451902103	[688,537]	[318,439]	3	hSpCas9	negative selection	4737135
55743729	55743751	12	-	27760321	HT1080	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.22839151503369493	[551,430]	[205,254]	1	hSpCas9	negative selection	4737136
55748673	55748695	12	-	27760321	HT1080	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	-0.23250856817910634	[539,421]	[196,125]	-1	hSpCas9	negative selection	4737137
55748748	55748770	12	+	27760321	HT1080	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-3.2915759449199338	[448,350]	[0,32]	-7	hSpCas9	negative selection	4737138
55748803	55748825	12	-	27760321	HT1080	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.317678903713892	[499,389]	[71,383]	1	hSpCas9	negative selection	4737139
55743502	55743524	12	-	27760321	HT29	viability after 7 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.2991032901057479	[688,537]	[953,1369,595]	4	hSpCas9	negative selection	4820598
55743729	55743751	12	-	27760321	HT29	viability after 7 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.005192613500106191	[551,430]	[675,733,501]	0	hSpCas9	negative selection	4820599
55748673	55748695	12	-	27760321	HT29	viability after 7 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.3553414222122272	[539,421]	[938,740,715]	5	hSpCas9	negative selection	4820600
55748748	55748770	12	+	27760321	HT29	viability after 7 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.6021750958470534	[448,350]	[434,201,390]	-7	hSpCas9	negative selection	4820601
55748803	55748825	12	-	27760321	HT29	viability after 7 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.41109285022598524	[499,389]	[889,630,777]	6	hSpCas9	negative selection	4820602
55743502	55743524	12	-	27760321	HT29	viability after 25 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.20245150135815093	[688,537]	[862,672,887]	2	hSpCas9	negative selection	4904061
55743729	55743751	12	-	27760321	HT29	viability after 25 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.16938877764569937	[551,430]	[354,627,962]	1	hSpCas9	negative selection	4904062
55748673	55748695	12	-	27760321	HT29	viability after 25 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.47565533360972767	[539,421]	[684,900,704]	5	hSpCas9	negative selection	4904063
55748748	55748770	12	+	27760321	HT29	viability after 25 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-1.0043939458685975	[448,350]	[258,145,281]	-6	hSpCas9	negative selection	4904064
55748803	55748825	12	-	27760321	HT29	viability after 25 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.6820571682789722	[499,389]	[759,925,757]	7	hSpCas9	negative selection	4904065
55743502	55743524	12	-	27760321	HT29	viability after 22 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.1570036443806635	[688,537]	[682,930,760]	1	hSpCas9	negative selection	4987524
55743729	55743751	12	-	27760321	HT29	viability after 22 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.22380758583863303	[551,430]	[559,377,519]	-2	hSpCas9	negative selection	4987525
55748673	55748695	12	-	27760321	HT29	viability after 22 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.41729982304024293	[539,421]	[869,552,801]	4	hSpCas9	negative selection	4987526
55748748	55748770	12	+	27760321	HT29	viability after 22 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.6252110901880897	[448,350]	[140,333,429]	-5	hSpCas9	negative selection	4987527
55748803	55748825	12	-	27760321	HT29	viability after 22 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.5930548628852748	[499,389]	[854,773,695]	6	hSpCas9	negative selection	4987528
55743502	55743524	12	-	27760321	HT29	viability after 19 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.4344772931060371	[688,537]	[915,581,1327]	4	hSpCas9	negative selection	5070987
55743729	55743751	12	-	27760321	HT29	viability after 19 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.3160955387802058	[551,430]	[643,213,513]	-3	hSpCas9	negative selection	5070988
55748673	55748695	12	-	27760321	HT29	viability after 19 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.7219681580146404	[539,421]	[812,1049,850]	7	hSpCas9	negative selection	5070989
55748748	55748770	12	+	27760321	HT29	viability after 19 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	0.01975685201951416	[448,350]	[288,194,872]	0	hSpCas9	negative selection	5070990
55748803	55748825	12	-	27760321	HT29	viability after 19 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.7592742745268057	[499,389]	[1256,906,475]	7	hSpCas9	negative selection	5070991
55743502	55743524	12	-	27760321	HT29	viability after 16 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.1387073361686626	[688,537]	[487,529,841]	-1	hSpCas9	negative selection	5154450
55743729	55743751	12	-	27760321	HT29	viability after 16 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.46600682960022316	[551,430]	[406,325,463]	-5	hSpCas9	negative selection	5154451
55748673	55748695	12	-	27760321	HT29	viability after 16 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.3149260108598473	[539,421]	[805,792,418]	3	hSpCas9	negative selection	5154452
55748748	55748770	12	+	27760321	HT29	viability after 16 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.3450660422742182	[448,350]	[306,341,403]	-4	hSpCas9	negative selection	5154453
55748803	55748825	12	-	27760321	HT29	viability after 16 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.7683361295706592	[499,389]	[1120,756,693]	8	hSpCas9	negative selection	5154454
55743502	55743524	12	-	27760321	HT29	viability after 13 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.07100413156924235	[688,537]	[1130,466,649]	0	hSpCas9	negative selection	5237913
55743729	55743751	12	-	27760321	HT29	viability after 13 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	0.02961123400180843	[551,430]	[435,841,474]	0	hSpCas9	negative selection	5237914
55748673	55748695	12	-	27760321	HT29	viability after 13 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.5802690486491788	[539,421]	[994,799,714]	7	hSpCas9	negative selection	5237915
55748748	55748770	12	+	27760321	HT29	viability after 13 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.2479379880645935	[448,350]	[292,546,335]	-3	hSpCas9	negative selection	5237916
55748803	55748825	12	-	27760321	HT29	viability after 13 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.5326689615706721	[499,389]	[799,606,827]	7	hSpCas9	negative selection	5237917
55743502	55743524	12	-	27760321	HT29	viability after 10 days	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.019393371202333753	[688,537]	[724,744,795]	0	hSpCas9	negative selection	5321376
55743729	55743751	12	-	27760321	HT29	viability after 10 days	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	-0.20171062133640322	[551,430]	[587,694,326]	-3	hSpCas9	negative selection	5321377
55748673	55748695	12	-	27760321	HT29	viability after 10 days	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.7102325338042068	[539,421]	[1013,893,1035]	8	hSpCas9	negative selection	5321378
55748748	55748770	12	+	27760321	HT29	viability after 10 days	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.6157500218370542	[448,350]	[256,440,283]	-6	hSpCas9	negative selection	5321379
55748803	55748825	12	-	27760321	HT29	viability after 10 days	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.6235873288003075	[499,389]	[1050,771,744]	8	hSpCas9	negative selection	5321380
55743502	55743524	12	-	27760321	MOLM13	viability	CTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.04976641032574369	[815,688]	[587,255]	0	hSpCas9	negative selection	5404839
55743729	55743751	12	-	27760321	MOLM13	viability	ATGCTAATGACGGTCTCGGTGG	GDF11	ENSG00000135414	1.0677753017284912	[590,551]	[1217,214]	7	hSpCas9	negative selection	5404840
55748673	55748695	12	-	27760321	MOLM13	viability	CGTAGGTACACCCACAGCTGGG	GDF11	ENSG00000135414	0.6894469911125712	[657,539]	[516,563]	5	hSpCas9	negative selection	5404841
55748748	55748770	12	+	27760321	MOLM13	viability	TAACTGGGGAAGGGACCGCAGG	GDF11	ENSG00000135414	-0.023131550077867075	[577,448]	[274,289]	0	hSpCas9	negative selection	5404842
55748803	55748825	12	-	27760321	MOLM13	viability	CAGCTCAATCTTCAGTGAGCGG	GDF11	ENSG00000135414	0.19974568277489024	[612,499]	[502,235]	1	hSpCas9	negative selection	5404843
55743794	55743817	12	+	27661255	K562	viability	GCTGGCTCTGGCCCCGCGAAGGG	GDF11	ENSG00000135414	0.2647579082394753	[569,655]	[656,526]	8	dCas9-KRAB	negative selection	5481804
55743308	55743331	12	-	27661255	K562	viability	GCCGCGAGCACCATGCTGGAGGG	GDF11	ENSG00000135414	0.07735993403080443	[203,250]	[210,173]	2	dCas9-KRAB	negative selection	5481805
55743502	55743525	12	-	27661255	K562	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.47369461953905634	[127,176]	[185,152]	9	dCas9-KRAB	negative selection	5481806
55743726	55743749	12	-	27661255	K562	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	0.07043234698342671	[1221,1152]	[1002,991]	2	dCas9-KRAB	negative selection	5481807
55749655	55749678	12	-	27260156	BXPC3	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.05402962570830683	[240]	[168,311,264,311]	1	hSpCas9	negative selection	5545002
55749648	55749671	12	+	27260156	BXPC3	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.3263216434802845	[415]	[585,532,484,571]	7	hSpCas9	negative selection	5545003
55748732	55748755	12	+	27260156	BXPC3	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.038855947554009396	[367]	[361,298,452,485]	0	hSpCas9	negative selection	5545004
55743495	55743518	12	+	27260156	BXPC3	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.038165546209326245	[400]	[337,487,365,546]	0	hSpCas9	negative selection	5609266
55743504	55743527	12	-	27260156	BXPC3	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.2629892108291865	[283]	[261,460,327,377]	6	hSpCas9	negative selection	5609267
55748650	55748673	12	+	27260156	BXPC3	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.1810745286308803	[622]	[426,652,594,638]	-4	hSpCas9	negative selection	5609268
55749655	55749678	12	-	27260156	A673	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.002290932505604304	[240]	[296,303,186,376]	0	hSpCas9	negative selection	5666253
55749648	55749671	12	+	27260156	A673	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.2805203201768448	[415]	[662,427,673,674]	6	hSpCas9	negative selection	5666254
55748732	55748755	12	+	27260156	A673	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.2926808844548055	[367]	[350,346,356,387]	-6	hSpCas9	negative selection	5666255
55743495	55743518	12	+	27260156	A673	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.01019164695515945	[400]	[473,515,414,534]	0	hSpCas9	negative selection	5730517
55743504	55743527	12	-	27260156	A673	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.16474718525947918	[283]	[335,351,453,380]	4	hSpCas9	negative selection	5730518
55748650	55748673	12	+	27260156	A673	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.16058566620400758	[622]	[745,617,696,621]	-4	hSpCas9	negative selection	5730519
55749655	55749678	12	-	27260156	A375	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.06362844222946085	[240]	[264,531,251,173]	0	hSpCas9	negative selection	5787504
55749648	55749671	12	+	27260156	A375	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.42090724977418137	[415]	[814,545,693,543]	6	hSpCas9	negative selection	5787505
55748732	55748755	12	+	27260156	A375	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.09533117195083934	[367]	[481,188,461,440]	-1	hSpCas9	negative selection	5787506
55743495	55743518	12	+	27260156	A375	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.03288145558733985	[400]	[576,348,521,376]	0	hSpCas9	negative selection	5851768
55743504	55743527	12	-	27260156	A375	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.08955398240291257	[283]	[334,404,254,414]	1	hSpCas9	negative selection	5851769
55748650	55748673	12	+	27260156	A375	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.1749192791172526	[622]	[650,786,608,558]	-3	hSpCas9	negative selection	5851770
55749655	55749678	12	-	27260156	COLO741	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.009428682359396978	[240]	[304,319,292]	0	hSpCas9	negative selection	5908755
55749648	55749671	12	+	27260156	COLO741	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.4793353619097366	[415]	[833,778,624]	8	hSpCas9	negative selection	5908756
55748732	55748755	12	+	27260156	COLO741	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.08607880454778616	[367]	[455,486,545]	1	hSpCas9	negative selection	5908757
55743495	55743518	12	+	27260156	COLO741	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.04280774961652839	[400]	[461,687,433]	0	hSpCas9	negative selection	5973019
55743504	55743527	12	-	27260156	COLO741	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.26781763930180996	[283]	[464,409,436]	5	hSpCas9	negative selection	5973020
55748650	55748673	12	+	27260156	COLO741	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.08848344391347196	[622]	[796,823,635]	-2	hSpCas9	negative selection	5973021
55749655	55749678	12	-	27260156	CAL120	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.3860503483453346	[240]	[522,431,242]	6	hSpCas9	negative selection	6030006
55749648	55749671	12	+	27260156	CAL120	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.4255848018098407	[415]	[1183,553,425]	6	hSpCas9	negative selection	6030007
55748732	55748755	12	+	27260156	CAL120	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.4135136631439817	[367]	[369,363,301]	-5	hSpCas9	negative selection	6030008
55743495	55743518	12	+	27260156	CAL120	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.30186774135456745	[400]	[645,339,266]	-4	hSpCas9	negative selection	6094270
55743504	55743527	12	-	27260156	CAL120	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.29009396570560797	[283]	[289,392,185]	-4	hSpCas9	negative selection	6094271
55748650	55748673	12	+	27260156	CAL120	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.599600197429449	[622]	[521,602,412]	-7	hSpCas9	negative selection	6094272
55749655	55749678	12	-	27260156	CADOES1	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.03725838446098351	[240]	[204,129,333,203]	0	hSpCas9	negative selection	6151257
55749648	55749671	12	+	27260156	CADOES1	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.2281168833219618	[415]	[488,469,417,434]	4	hSpCas9	negative selection	6151258
55748732	55748755	12	+	27260156	CADOES1	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.0946831773041662	[367]	[261,349,356,312]	-2	hSpCas9	negative selection	6151259
55743495	55743518	12	+	27260156	CADOES1	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.10449634390856938	[400]	[384,320,370,308]	-2	hSpCas9	negative selection	6215521
55743504	55743527	12	-	27260156	CADOES1	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.4234018970645434	[283]	[356,447,413,191]	7	hSpCas9	negative selection	6215522
55748650	55748673	12	+	27260156	CADOES1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.4702114804231676	[622]	[416,323,534,395]	-7	hSpCas9	negative selection	6215523
55749655	55749678	12	-	27260156	EWS502	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.22669780391813144	[240]	[395,325,169,285]	4	hSpCas9	negative selection	6272508
55749648	55749671	12	+	27260156	EWS502	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.06075562790445371	[415]	[406,486,458,490]	1	hSpCas9	negative selection	6272509
55748732	55748755	12	+	27260156	EWS502	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.14714518563854567	[367]	[212,396,478,332]	-3	hSpCas9	negative selection	6272510
55743495	55743518	12	+	27260156	EWS502	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.012656309344567934	[400]	[406,389,415,508]	0	hSpCas9	negative selection	6336772
55743504	55743527	12	-	27260156	EWS502	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.31751606715525715	[283]	[160,258,242,315]	-5	hSpCas9	negative selection	6336773
55748650	55748673	12	+	27260156	EWS502	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.24931515547949956	[622]	[535,632,567,474]	-4	hSpCas9	negative selection	6336774
55749655	55749678	12	-	27260156	EW8	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.2819009805067394	[240]	[234,202,222,289]	5	hSpCas9	negative selection	6393759
55749648	55749671	12	+	27260156	EW8	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.24460238922386587	[415]	[241,486,455,384]	4	hSpCas9	negative selection	6393760
55748732	55748755	12	+	27260156	EW8	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.10250107906960121	[367]	[335,235,283,430]	1	hSpCas9	negative selection	6393761
55743495	55743518	12	+	27260156	EW8	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.21885598590331878	[400]	[309,390,203,227]	-4	hSpCas9	negative selection	6458023
55743504	55743527	12	-	27260156	EW8	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.01639343931767212	[283]	[272,254,148,250]	0	hSpCas9	negative selection	6458024
55748650	55748673	12	+	27260156	EW8	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.08136095774781699	[622]	[560,509,351,514]	-1	hSpCas9	negative selection	6458025
55749655	55749678	12	-	27260156	CORL105	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.16840027756588782	[240]	[339,214,506,238]	3	hSpCas9	negative selection	6515010
55749648	55749671	12	+	27260156	CORL105	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.47474237835564326	[415]	[691,722,765,539]	8	hSpCas9	negative selection	6515011
55748732	55748755	12	+	27260156	CORL105	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.42543834688839355	[367]	[533,582,657,549]	7	hSpCas9	negative selection	6515012
55743495	55743518	12	+	27260156	CORL105	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.14568972019420823	[400]	[530,443,695,435]	2	hSpCas9	negative selection	6579274
55743504	55743527	12	-	27260156	CORL105	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.12118588230331595	[283]	[196,309,371,349]	-2	hSpCas9	negative selection	6579275
55748650	55748673	12	+	27260156	CORL105	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.19575720705039848	[622]	[828,476,712,549]	-4	hSpCas9	negative selection	6579276
55749655	55749678	12	-	27260156	HS294T	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.384398663749669	[240]	[98,103,118,175]	5	hSpCas9	negative selection	6636261
55749648	55749671	12	+	27260156	HS294T	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.06696782424855562	[415]	[178,137,159,201]	0	hSpCas9	negative selection	6636262
55748732	55748755	12	+	27260156	HS294T	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	1.0067505715757659	[367]	[234,246,360,309]	9	hSpCas9	negative selection	6636263
55743495	55743518	12	+	27260156	HS294T	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.2306995659900026	[400]	[262,139,103,219]	3	hSpCas9	negative selection	6700525
55743504	55743527	12	-	27260156	HS294T	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.19452796049817767	[283]	[100,125,164,109]	2	hSpCas9	negative selection	6700526
55748650	55748673	12	+	27260156	HS294T	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.1636441519441049	[622]	[316,186,133,211]	-2	hSpCas9	negative selection	6700527
55749655	55749678	12	-	27260156	HCC44	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.2123407738624311	[240]	[208,251,488,338]	3	hSpCas9	negative selection	6757512
55749648	55749671	12	+	27260156	HCC44	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.39371823263352657	[415]	[725,681,608,454]	6	hSpCas9	negative selection	6757513
55748732	55748755	12	+	27260156	HCC44	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.4401384810502533	[367]	[694,321,982,378]	7	hSpCas9	negative selection	6757514
55743495	55743518	12	+	27260156	HCC44	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	0.12819322749379125	[400]	[270,367,700,665]	2	hSpCas9	negative selection	6821776
55743504	55743527	12	-	27260156	HCC44	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.7208416364389081	[283]	[363,929,353,367]	9	hSpCas9	negative selection	6821777
55748650	55748673	12	+	27260156	HCC44	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.08411542117781812	[622]	[1010,498,752,777]	1	hSpCas9	negative selection	6821778
55749655	55749678	12	-	27260156	G402	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.5400776526566231	[240]	[548,301,356,506]	6	hSpCas9	negative selection	6878763
55749648	55749671	12	+	27260156	G402	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.7343541833960825	[415]	[883,1098,776,644]	8	hSpCas9	negative selection	6878764
55748732	55748755	12	+	27260156	G402	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.6592496764626641	[367]	[458,1051,753,559]	7	hSpCas9	negative selection	6878765
55743495	55743518	12	+	27260156	G402	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.027863632588294274	[400]	[478,593,235,608]	0	hSpCas9	negative selection	6943027
55743504	55743527	12	-	27260156	G402	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.15528486879451409	[283]	[429,337,608,178]	2	hSpCas9	negative selection	6943028
55748650	55748673	12	+	27260156	G402	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.6129136247331154	[622]	[574,484,632,312]	-6	hSpCas9	negative selection	6943029
55749655	55749678	12	-	27260156	L33	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.14339256070262496	[240]	[212,86,114,263]	-3	hSpCas9	negative selection	7000014
55749648	55749671	12	+	27260156	L33	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.054258713768273376	[415]	[421,154,277,359]	-1	hSpCas9	negative selection	7000015
55748732	55748755	12	+	27260156	L33	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.016805923235663267	[367]	[276,151,202,518]	0	hSpCas9	negative selection	7000016
55743495	55743518	12	+	27260156	L33	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.052855552250058946	[400]	[343,174,243,387]	-1	hSpCas9	negative selection	7064278
55743504	55743527	12	-	27260156	L33	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.34148701329271225	[283]	[363,158,202,363]	7	hSpCas9	negative selection	7064279
55748650	55748673	12	+	27260156	L33	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.09803286363776414	[622]	[500,249,420,549]	-2	hSpCas9	negative selection	7064280
55749655	55749678	12	-	27260156	K562	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.22068539723416447	[240]	[242,90,516,147]	2	hSpCas9	negative selection	7121265
55749648	55749671	12	+	27260156	K562	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.5495066063354803	[415]	[748,482,626,337]	7	hSpCas9	negative selection	7121266
55748732	55748755	12	+	27260156	K562	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.23839952376417423	[367]	[269,192,519,134]	-3	hSpCas9	negative selection	7121267
55743495	55743518	12	+	27260156	K562	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.0135573757351381	[400]	[525,285,430,194]	0	hSpCas9	negative selection	7185529
55743504	55743527	12	-	27260156	K562	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.14880568872979472	[283]	[225,197,427,72]	-2	hSpCas9	negative selection	7185530
55748650	55748673	12	+	27260156	K562	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.38505931968224494	[622]	[743,618,147,238]	-5	hSpCas9	negative selection	7185531
55749655	55749678	12	-	27260156	HT29	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.29518545353253534	[240]	[429,380,320,315]	6	hSpCas9	negative selection	7242516
55749648	55749671	12	+	27260156	HT29	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.262497322434158	[415]	[724,579,500,620]	5	hSpCas9	negative selection	7242517
55748732	55748755	12	+	27260156	HT29	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.09821311446418712	[367]	[590,318,368,396]	-2	hSpCas9	negative selection	7242518
55743495	55743518	12	+	27260156	HT29	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.26556044428118225	[400]	[411,364,378,453]	-5	hSpCas9	negative selection	7306780
55743504	55743527	12	-	27260156	HT29	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.3261428360152377	[283]	[543,400,428,367]	6	hSpCas9	negative selection	7306781
55748650	55748673	12	+	27260156	HT29	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.033082892298556155	[622]	[731,674,747,787]	0	hSpCas9	negative selection	7306782
55749655	55749678	12	-	27260156	MHHES1	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.08268409646790675	[240]	[324,123,240,310]	-1	hSpCas9	negative selection	7363767
55749648	55749671	12	+	27260156	MHHES1	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.008537968461180823	[415]	[486,481,532,393]	0	hSpCas9	negative selection	7363768
55748732	55748755	12	+	27260156	MHHES1	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.5038585029827882	[367]	[686,503,599,556]	8	hSpCas9	negative selection	7363769
55743495	55743518	12	+	27260156	MHHES1	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.18875492632822083	[400]	[467,477,427,252]	-4	hSpCas9	negative selection	7428031
55743504	55743527	12	-	27260156	MHHES1	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.33208390163454515	[283]	[428,646,363,229]	6	hSpCas9	negative selection	7428032
55748650	55748673	12	+	27260156	MHHES1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.16948427610061712	[622]	[955,1034,523,689]	3	hSpCas9	negative selection	7428033
55749655	55749678	12	-	27260156	MEWO	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.01974923956200081	[240]	[367,165,178]	0	hSpCas9	negative selection	7485018
55749648	55749671	12	+	27260156	MEWO	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.010343698337983098	[415]	[598,391,224]	0	hSpCas9	negative selection	7485019
55748732	55748755	12	+	27260156	MEWO	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.2131760942561512	[367]	[328,320,246]	-5	hSpCas9	negative selection	7485020
55743495	55743518	12	+	27260156	MEWO	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.3218065698128875	[400]	[344,316,246]	-6	hSpCas9	negative selection	7549282
55743504	55743527	12	-	27260156	MEWO	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.24044200624411494	[283]	[361,294,293]	5	hSpCas9	negative selection	7549283
55748650	55748673	12	+	27260156	MEWO	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2900370261831574	[622]	[546,400,495]	-6	hSpCas9	negative selection	7549284
55749655	55749678	12	-	27260156	LNCAPCLONEFGC	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.06550416433264128	[240]	[88,288,212,240]	-1	hSpCas9	negative selection	7606269
55749648	55749671	12	+	27260156	LNCAPCLONEFGC	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.401024527581582	[415]	[409,548,582,458]	6	hSpCas9	negative selection	7606270
55748732	55748755	12	+	27260156	LNCAPCLONEFGC	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.1805577365511095	[367]	[409,327,366,406]	3	hSpCas9	negative selection	7606271
55743495	55743518	12	+	27260156	LNCAPCLONEFGC	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.210382885274438	[400]	[182,345,407,332]	-3	hSpCas9	negative selection	7670533
55743504	55743527	12	-	27260156	LNCAPCLONEFGC	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.13815605388002017	[283]	[188,131,391,252]	-2	hSpCas9	negative selection	7670534
55748650	55748673	12	+	27260156	LNCAPCLONEFGC	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.17836672781125368	[622]	[482,383,596,552]	-3	hSpCas9	negative selection	7670535
55749655	55749678	12	-	27260156	PANC0327	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.5279012346964593	[240]	[515,304,229,200]	7	hSpCas9	negative selection	7727520
55749648	55749671	12	+	27260156	PANC0327	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.07430611422450399	[415]	[307,384,397,458]	1	hSpCas9	negative selection	7727521
55748732	55748755	12	+	27260156	PANC0327	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.11484394151585875	[367]	[205,205,373,425]	-2	hSpCas9	negative selection	7727522
55743495	55743518	12	+	27260156	PANC0327	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.5327313762954886	[400]	[272,253,221,236]	-6	hSpCas9	negative selection	7791784
55743504	55743527	12	-	27260156	PANC0327	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.18634937148044883	[283]	[287,82,199,338]	-3	hSpCas9	negative selection	7791785
55748650	55748673	12	+	27260156	PANC0327	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.3058358122326855	[622]	[380,379,515,516]	-4	hSpCas9	negative selection	7791786
55749655	55749678	12	-	27260156	NCIH2009	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.8772095639135966	[240]	[558,653,628]	9	hSpCas9	negative selection	7848771
55749648	55749671	12	+	27260156	NCIH2009	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.6425828076084721	[415]	[795,934,966]	8	hSpCas9	negative selection	7848772
55748732	55748755	12	+	27260156	NCIH2009	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.4150472838275079	[367]	[778,626,668]	6	hSpCas9	negative selection	7848773
55743495	55743518	12	+	27260156	NCIH2009	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.23034476603964077	[400]	[714,359,405]	-3	hSpCas9	negative selection	7913035
55743504	55743527	12	-	27260156	NCIH2009	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.4256407079285057	[283]	[670,436,518]	6	hSpCas9	negative selection	7913036
55748650	55748673	12	+	27260156	NCIH2009	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.28000790969028155	[622]	[651,858,622]	-4	hSpCas9	negative selection	7913037
55749655	55749678	12	-	27260156	NCIH1373	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.5163372594693163	[240]	[352,520,368,71]	5	hSpCas9	negative selection	7970022
55749648	55749671	12	+	27260156	NCIH1373	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.5151358275875191	[415]	[611,474,481,298]	5	hSpCas9	negative selection	7970023
55748732	55748755	12	+	27260156	NCIH1373	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.754270864163868	[367]	[403,611,907,215]	7	hSpCas9	negative selection	7970024
55743495	55743518	12	+	27260156	NCIH1373	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.12431458939557988	[400]	[309,398,254,180]	-1	hSpCas9	negative selection	8034286
55743504	55743527	12	-	27260156	NCIH1373	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.628041768663334	[283]	[149,217,304,34]	-6	hSpCas9	negative selection	8034287
55748650	55748673	12	+	27260156	NCIH1373	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.6551219549872038	[622]	[556,228,567,119]	-6	hSpCas9	negative selection	8034288
55749655	55749678	12	-	27260156	PATU8902	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.7249754361811012	[240]	[832,639,356,415]	7	hSpCas9	negative selection	8091273
55749648	55749671	12	+	27260156	PATU8902	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.8237695463443457	[415]	[834,1304,522,1637]	8	hSpCas9	negative selection	8091274
55748732	55748755	12	+	27260156	PATU8902	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.2811564311438155	[367]	[633,501,547,847]	3	hSpCas9	negative selection	8091275
55743495	55743518	12	+	27260156	PATU8902	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.4106841054701433	[400]	[429,402,376,485]	-4	hSpCas9	negative selection	8155537
55743504	55743527	12	-	27260156	PATU8902	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.3290259980095761	[283]	[554,326,137,274]	-3	hSpCas9	negative selection	8155538
55748650	55748673	12	+	27260156	PATU8902	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.3191216784404419	[622]	[1115,482,398,869]	-3	hSpCas9	negative selection	8155539
55749655	55749678	12	-	27260156	PANC1	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.18516377911504733	[240]	[282,222,241,192]	3	hSpCas9	negative selection	8212524
55749648	55749671	12	+	27260156	PANC1	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.06146056615033743	[415]	[301,477,426,311]	0	hSpCas9	negative selection	8212525
55748732	55748755	12	+	27260156	PANC1	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.2943731565159809	[367]	[262,372,245,180]	-5	hSpCas9	negative selection	8212526
55743495	55743518	12	+	27260156	PANC1	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.4560194020708764	[400]	[213,326,261,218]	-6	hSpCas9	negative selection	8276788
55743504	55743527	12	-	27260156	PANC1	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.30966134008747365	[283]	[260,424,387,177]	5	hSpCas9	negative selection	8276789
55748650	55748673	12	+	27260156	PANC1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.060206189167877344	[622]	[415,736,407,527]	-1	hSpCas9	negative selection	8276790
55749655	55749678	12	-	27260156	PANC0813	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.36230696210874946	[240]	[428,369,319,342]	6	hSpCas9	negative selection	8333775
55749648	55749671	12	+	27260156	PANC0813	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.07009137787480937	[415]	[511,390,538,603]	1	hSpCas9	negative selection	8333776
55748732	55748755	12	+	27260156	PANC0813	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.40147300222653265	[367]	[751,494,373,671]	6	hSpCas9	negative selection	8333777
55743495	55743518	12	+	27260156	PANC0813	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.0417905515068161	[400]	[484,491,417,437]	0	hSpCas9	negative selection	8398039
55743504	55743527	12	-	27260156	PANC0813	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.029207820158049902	[283]	[499,197,262,359]	0	hSpCas9	negative selection	8398040
55748650	55748673	12	+	27260156	PANC0813	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.1836195836261245	[622]	[645,762,525,640]	-3	hSpCas9	negative selection	8398041
55749655	55749678	12	-	27260156	RDES	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.12313201577864374	[240]	[215,308,251,231]	-2	hSpCas9	negative selection	8455026
55749648	55749671	12	+	27260156	RDES	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.33012513048402403	[415]	[681,520,570,597]	5	hSpCas9	negative selection	8455027
55748732	55748755	12	+	27260156	RDES	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.2711942122535153	[367]	[411,483,463,721]	4	hSpCas9	negative selection	8455028
55743495	55743518	12	+	27260156	RDES	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.02402965063627316	[400]	[366,538,471,428]	0	hSpCas9	negative selection	8519290
55743504	55743527	12	-	27260156	RDES	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.04852865237024728	[283]	[378,265,278,316]	-1	hSpCas9	negative selection	8519291
55748650	55748673	12	+	27260156	RDES	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.6828179953943696	[622]	[386,401,414,607]	-8	hSpCas9	negative selection	8519292
55749655	55749678	12	-	27260156	PC3	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.08087689317176505	[240]	[208,184,299,335]	1	hSpCas9	negative selection	8576277
55749648	55749671	12	+	27260156	PC3	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.28230326573883663	[415]	[347,605,725,427]	6	hSpCas9	negative selection	8576278
55748732	55748755	12	+	27260156	PC3	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.3367914941094842	[367]	[165,295,630,226]	-6	hSpCas9	negative selection	8576279
55743495	55743518	12	+	27260156	PC3	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.30258222883403746	[400]	[190,315,514,379]	-6	hSpCas9	negative selection	8640541
55743504	55743527	12	-	27260156	PC3	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.07046667037191656	[283]	[185,180,565,274]	-1	hSpCas9	negative selection	8640542
55748650	55748673	12	+	27260156	PC3	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.11394127473702964	[622]	[269,672,661,817]	-3	hSpCas9	negative selection	8640543
55749655	55749678	12	-	27260156	PATU8988T	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.4641617798237007	[240]	[218,348,499,207]	7	hSpCas9	negative selection	8697528
55749648	55749671	12	+	27260156	PATU8988T	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.1353841150814148	[415]	[469,445,427,420]	2	hSpCas9	negative selection	8697529
55748732	55748755	12	+	27260156	PATU8988T	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.37456340039064695	[367]	[541,455,390,454]	6	hSpCas9	negative selection	8697530
55743495	55743518	12	+	27260156	PATU8988T	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.23903348369180694	[400]	[302,454,330,227]	-4	hSpCas9	negative selection	8761792
55743504	55743527	12	-	27260156	PATU8988T	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.5698867583875822	[283]	[462,401,401,357]	8	hSpCas9	negative selection	8761793
55748650	55748673	12	+	27260156	PATU8988T	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.17900647072437603	[622]	[821,660,597,640]	3	hSpCas9	negative selection	8761794
55749655	55749678	12	-	27260156	T47D	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.33328217917346703	[240]	[369,365,308,369]	7	hSpCas9	negative selection	8818779
55749648	55749671	12	+	27260156	T47D	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.305508363736527	[415]	[587,665,610,521]	6	hSpCas9	negative selection	8818780
55748732	55748755	12	+	27260156	T47D	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.03070036274214677	[367]	[477,400,396,480]	0	hSpCas9	negative selection	8818781
55743495	55743518	12	+	27260156	T47D	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.3001898891351868	[400]	[315,307,461,437]	-6	hSpCas9	negative selection	8883043
55743504	55743527	12	-	27260156	T47D	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	-0.0009142832548008073	[283]	[336,262,342,386]	0	hSpCas9	negative selection	8883044
55748650	55748673	12	+	27260156	T47D	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2313466327141634	[622]	[739,519,605,615]	-5	hSpCas9	negative selection	8883045
55749655	55749678	12	-	27260156	SU8686	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.046108644555919676	[240]	[185,213,296,310]	0	hSpCas9	negative selection	8940030
55749648	55749671	12	+	27260156	SU8686	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.263661197042656	[415]	[413,547,416,617]	4	hSpCas9	negative selection	8940031
55748732	55748755	12	+	27260156	SU8686	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.10201452643250658	[367]	[379,407,396,374]	1	hSpCas9	negative selection	8940032
55743495	55743518	12	+	27260156	SU8686	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.1006712303104565	[400]	[387,323,422,346]	-2	hSpCas9	negative selection	9004294
55743504	55743527	12	-	27260156	SU8686	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.01603184833192761	[283]	[237,323,265,312]	0	hSpCas9	negative selection	9004295
55748650	55748673	12	+	27260156	SU8686	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.437313061445906	[622]	[356,364,643,488]	-6	hSpCas9	negative selection	9004296
55749655	55749678	12	-	27260156	SKES1	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.010890060537114943	[240]	[188,296,251,228]	0	hSpCas9	negative selection	9061281
55749648	55749671	12	+	27260156	SKES1	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.35649506915309725	[415]	[658,546,529,416]	7	hSpCas9	negative selection	9061282
55748732	55748755	12	+	27260156	SKES1	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.010240367580300669	[367]	[325,367,360,390]	0	hSpCas9	negative selection	9061283
55743495	55743518	12	+	27260156	SKES1	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.3540742955947766	[400]	[419,251,296,289]	-7	hSpCas9	negative selection	9125545
55743504	55743527	12	-	27260156	SKES1	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.4462733637037618	[283]	[448,532,337,261]	8	hSpCas9	negative selection	9125546
55748650	55748673	12	+	27260156	SKES1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.39433611121907425	[622]	[469,580,446,408]	-7	hSpCas9	negative selection	9125547
55749655	55749678	12	-	27260156	TOV112D	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.04594534757136404	[240]	[298,269,173,206]	-1	hSpCas9	negative selection	9182532
55749648	55749671	12	+	27260156	TOV112D	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.5134000840774428	[415]	[609,876,487,476]	8	hSpCas9	negative selection	9182533
55748732	55748755	12	+	27260156	TOV112D	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.30939937574046145	[367]	[265,121,225,522]	-6	hSpCas9	negative selection	9182534
55743495	55743518	12	+	27260156	TOV112D	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.045808146464470734	[400]	[472,497,210,406]	-1	hSpCas9	negative selection	9246796
55743504	55743527	12	-	27260156	TOV112D	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.1938721998995856	[283]	[330,308,247,406]	4	hSpCas9	negative selection	9246797
55748650	55748673	12	+	27260156	TOV112D	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.05416739733587628	[622]	[651,899,371,557]	-1	hSpCas9	negative selection	9246798
55749655	55749678	12	-	27260156	TC71	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	-0.13070729594954322	[240]	[214,209,229,292]	-3	hSpCas9	negative selection	9303783
55749648	55749671	12	+	27260156	TC71	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	-0.2005933585041963	[415]	[406,402,322,422]	-5	hSpCas9	negative selection	9303784
55748732	55748755	12	+	27260156	TC71	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	-0.1926422529284782	[367]	[375,295,365,340]	-5	hSpCas9	negative selection	9303785
55743495	55743518	12	+	27260156	TC71	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.2960766671765545	[400]	[342,328,313,419]	-7	hSpCas9	negative selection	9368047
55743504	55743527	12	-	27260156	TC71	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.09383741545025703	[283]	[236,283,424,353]	2	hSpCas9	negative selection	9368048
55748650	55748673	12	+	27260156	TC71	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.13511654499615927	[622]	[694,547,573,614]	-4	hSpCas9	negative selection	9368049
55749655	55749678	12	-	27260156	TC32	viability	TAGTTGGCCTTGTAGCGCTTAGG	GDF11	ENSG00000135414	0.18175193682040613	[240]	[332,213,294,176]	3	hSpCas9	negative selection	9425034
55749648	55749671	12	+	27260156	TC32	viability	CATCGCACCTAAGCGCTACAAGG	GDF11	ENSG00000135414	0.26923808105297253	[415]	[373,502,440,533]	5	hSpCas9	negative selection	9425035
55748732	55748755	12	+	27260156	TC32	viability	TTGCGACTAAAACCCCTAACTGG	GDF11	ENSG00000135414	0.0348754006577921	[367]	[247,343,400,431]	0	hSpCas9	negative selection	9425036
55743495	55743518	12	+	27260156	TC32	viability	ACGGCTGCCCCGTGTGCGTTTGG	GDF11	ENSG00000135414	-0.28558096910450564	[400]	[298,231,305,416]	-5	hSpCas9	negative selection	9489298
55743504	55743527	12	-	27260156	TC32	viability	GTGCTGCCGCCAAACGCACACGG	GDF11	ENSG00000135414	0.09252398192849531	[283]	[266,128,351,457]	1	hSpCas9	negative selection	9489299
55748650	55748673	12	+	27260156	TC32	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2949735024537183	[622]	[557,260,601,557]	-5	hSpCas9	negative selection	9489300
55743502	55743525	12	-	27869803	HPAFII	viability after 27 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-2.351278918619773	[119]	[19,5,NaN]	-8	hSpCas9	negative selection	9547630
55743721	55743744	12	-	27869803	HPAFII	viability after 27 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.6077385092751497	[533]	[543,330,NaN]	5	hSpCas9	negative selection	9547631
55748674	55748697	12	-	27869803	HPAFII	viability after 27 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.280588273553092	[522]	[173,269,NaN]	-2	hSpCas9	negative selection	9547632
55748926	55748949	12	+	27869803	HPAFII	viability after 27 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.6184610702626043	[501]	[190,155,NaN]	-4	hSpCas9	negative selection	9547633
55749546	55749569	12	-	27869803	HPAFII	viability after 27 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.5976056097453082	[201]	[85,56,NaN]	-4	hSpCas9	negative selection	9547634
55749687	55749710	12	-	27869803	HPAFII	viability after 27 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.0897720383010252	[402]	[119,264,NaN]	0	hSpCas9	negative selection	9547635
55743502	55743525	12	-	27869803	HPAFII	viability after 15 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-1.0534654076819	[119]	[108,32,NaN]	-8	hSpCas9	negative selection	9630079
55743721	55743744	12	-	27869803	HPAFII	viability after 15 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.17656765778489913	[533]	[1070,385,NaN]	2	hSpCas9	negative selection	9630080
55748674	55748697	12	-	27869803	HPAFII	viability after 15 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.0649225478408566	[522]	[648,549,NaN]	0	hSpCas9	negative selection	9630081
55748926	55748949	12	+	27869803	HPAFII	viability after 15 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.04084037362624193	[501]	[759,377,NaN]	0	hSpCas9	negative selection	9630082
55749546	55749569	12	-	27869803	HPAFII	viability after 15 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	0.06588902606586622	[201]	[299,181,NaN]	0	hSpCas9	negative selection	9630083
55749687	55749710	12	-	27869803	HPAFII	viability after 15 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.08459276725653697	[402]	[413,404,NaN]	-1	hSpCas9	negative selection	9630084
55743502	55743525	12	-	27869803	ASPC1	viability after 36 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	1.0459697824945868	[173]	[101,280,16]	8	hSpCas9	negative selection	9712528
55743721	55743744	12	-	27869803	ASPC1	viability after 36 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	-0.6551137870414544	[1482]	[420,467,149]	-6	hSpCas9	negative selection	9712529
55748674	55748697	12	-	27869803	ASPC1	viability after 36 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.2151260093486691	[1114]	[445,325,550]	2	hSpCas9	negative selection	9712530
55748926	55748949	12	+	27869803	ASPC1	viability after 36 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	0.2983173244387991	[1629]	[702,671,711]	3	hSpCas9	negative selection	9712531
55749546	55749569	12	-	27869803	ASPC1	viability after 36 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.07384577553090169	[595]	[292,190,133]	0	hSpCas9	negative selection	9712532
55749687	55749710	12	-	27869803	ASPC1	viability after 36 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	0.36663975821247785	[828]	[429,181,480]	3	hSpCas9	negative selection	9712533
55743502	55743525	12	-	27869803	PATU8988S	viability after 35 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.3973040509692405	[223]	[67,68,NaN]	-4	hSpCas9	negative selection	9794977
55743721	55743744	12	-	27869803	PATU8988S	viability after 35 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	1.0301026109613043	[1062]	[1005,741,NaN]	9	hSpCas9	negative selection	9794978
55748674	55748697	12	-	27869803	PATU8988S	viability after 35 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.6555288626592553	[922]	[233,237,NaN]	-6	hSpCas9	negative selection	9794979
55748926	55748949	12	+	27869803	PATU8988S	viability after 35 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.7998736148938363	[1248]	[263,313,NaN]	-7	hSpCas9	negative selection	9794980
55749546	55749569	12	-	27869803	PATU8988S	viability after 35 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.30884454365872005	[594]	[173,212,NaN]	-3	hSpCas9	negative selection	9794981
55749687	55749710	12	-	27869803	PATU8988S	viability after 35 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.930371845603879	[692]	[125,166,NaN]	-7	hSpCas9	negative selection	9794982
55743502	55743525	12	-	27869803	PATU8988S	viability after 31 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.40017593134834106	[223]	[79,51,NaN]	-4	hSpCas9	negative selection	9877426
55743721	55743744	12	-	27869803	PATU8988S	viability after 31 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	1.1680015299890654	[1062]	[874,1050,NaN]	9	hSpCas9	negative selection	9877427
55748674	55748697	12	-	27869803	PATU8988S	viability after 31 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.2949445752569801	[922]	[255,355,NaN]	-3	hSpCas9	negative selection	9877428
55748926	55748949	12	+	27869803	PATU8988S	viability after 31 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.7039648062844736	[1248]	[171,475,NaN]	-6	hSpCas9	negative selection	9877429
55749546	55749569	12	-	27869803	PATU8988S	viability after 31 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	0.04625244651211305	[594]	[156,356,NaN]	0	hSpCas9	negative selection	9877430
55749687	55749710	12	-	27869803	PATU8988S	viability after 31 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.6944594750529497	[692]	[146,200,NaN]	-6	hSpCas9	negative selection	9877431
55743502	55743525	12	-	27869803	HPAFII	viability after 35 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-2.2047572283197368	[119]	[15,9,NaN]	-8	hSpCas9	negative selection	9959875
55743721	55743744	12	-	27869803	HPAFII	viability after 35 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.4084223441899566	[533]	[307,415,NaN]	2	hSpCas9	negative selection	9959876
55748674	55748697	12	-	27869803	HPAFII	viability after 35 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	0.13474786732240296	[522]	[134,465,NaN]	0	hSpCas9	negative selection	9959877
55748926	55748949	12	+	27869803	HPAFII	viability after 35 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.9738581459030783	[501]	[87,175,NaN]	-5	hSpCas9	negative selection	9959878
55749546	55749569	12	-	27869803	HPAFII	viability after 35 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.804735073987177	[201]	[82,30,NaN]	-5	hSpCas9	negative selection	9959879
55749687	55749710	12	-	27869803	HPAFII	viability after 35 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.2878191719598153	[402]	[49,298,NaN]	-2	hSpCas9	negative selection	9959880
55743502	55743525	12	-	27869803	HPAFII	viability after 31 days	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-1.2312588589274553	[119]	[43,11,NaN]	-6	hSpCas9	negative selection	10042324
55743721	55743744	12	-	27869803	HPAFII	viability after 31 days	TGACGGTCTCGGTGGTGGCGTGG	GDF11	ENSG00000135414	0.23719184615245847	[533]	[380,322,NaN]	1	hSpCas9	negative selection	10042325
55748674	55748697	12	-	27869803	HPAFII	viability after 31 days	GCCGTAGGTACACCCACAGCTGG	GDF11	ENSG00000135414	-0.06085403903049835	[522]	[211,356,NaN]	0	hSpCas9	negative selection	10042326
55748926	55748949	12	+	27869803	HPAFII	viability after 31 days	TGATCCCAGTGGCACAGACCTGG	GDF11	ENSG00000135414	-0.9869020654853493	[501]	[111,174,NaN]	-6	hSpCas9	negative selection	10042327
55749546	55749569	12	-	27869803	HPAFII	viability after 31 days	AGTCCAGACCCAGGTTCCGCCGG	GDF11	ENSG00000135414	-0.41278464205067705	[201]	[43,129,NaN]	-3	hSpCas9	negative selection	10042328
55749687	55749710	12	-	27869803	HPAFII	viability after 31 days	GCATGAACATGTACTCGCACTGG	GDF11	ENSG00000135414	-0.3721751544368713	[402]	[101,253,NaN]	-3	hSpCas9	negative selection	10042329
55743604	55743627	12	-	28162770	P31FUJ	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.38017467247637415	[526]	[805]	4	hSpCas9	negative selection	10161415
55743726	55743749	12	-	28162770	P31FUJ	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-0.9406214529210682	[146]	[89]	-6	hSpCas9	negative selection	10161416
55743688	55743711	12	+	28162770	P31FUJ	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.545238850324443	[302]	[60]	-8	hSpCas9	negative selection	10161417
55743502	55743525	12	-	28162770	P31FUJ	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.3477379712590385	[221]	[204]	-3	hSpCas9	negative selection	10161418
55743592	55743615	12	+	28162770	P31FUJ	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.21362989513953268	[298]	[302]	-2	hSpCas9	negative selection	10161419
55743330	55743353	12	-	28162770	P31FUJ	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.8128404611413338	[139]	[288]	8	hSpCas9	negative selection	10161420
55748650	55748673	12	+	28162770	P31FUJ	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2375401234210418	[304]	[303]	-2	hSpCas9	negative selection	10161421
55748712	55748735	12	-	28162770	P31FUJ	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	-0.04962110626979943	[324]	[368]	0	hSpCas9	negative selection	10161422
55748734	55748757	12	+	28162770	P31FUJ	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.17372379500894783	[254]	[337]	1	hSpCas9	negative selection	10161423
55743638	55743661	12	-	28162770	P31FUJ	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.2991255339849094	[313]	[453]	3	hSpCas9	negative selection	10161424
55743604	55743627	12	-	28162770	TF1	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	NaN	[NaN]	[534]	1	hSpCas9	negative selection	10330781
55743726	55743749	12	-	28162770	TF1	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10330782
55743688	55743711	12	+	28162770	TF1	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10330783
55743502	55743525	12	-	28162770	TF1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	NaN	[NaN]	[214]	1	hSpCas9	negative selection	10330784
55743592	55743615	12	+	28162770	TF1	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10330785
55743330	55743353	12	-	28162770	TF1	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10330786
55748650	55748673	12	+	28162770	TF1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	NaN	[NaN]	[639]	1	hSpCas9	negative selection	10330787
55748712	55748735	12	-	28162770	TF1	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	NaN	[NaN]	[312]	1	hSpCas9	negative selection	10330788
55748734	55748757	12	+	28162770	TF1	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10330789
55743638	55743661	12	-	28162770	TF1	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10330790
55743604	55743627	12	-	28162770	SKM1	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.016088750138307795	[142]	[249]	0	hSpCas9	negative selection	10500147
55743726	55743749	12	-	28162770	SKM1	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.8220016980220055	[19]	[9]	-8	hSpCas9	negative selection	10500148
55743688	55743711	12	+	28162770	SKM1	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.0820645373245084	[96]	[80]	-7	hSpCas9	negative selection	10500149
55743502	55743525	12	-	28162770	SKM1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	1.6030198898294605	[53]	[289]	9	hSpCas9	negative selection	10500150
55743592	55743615	12	+	28162770	SKM1	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.12286817738153799	[84]	[137]	-1	hSpCas9	negative selection	10500151
55743330	55743353	12	-	28162770	SKM1	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.0259952085329445	[24]	[89]	8	hSpCas9	negative selection	10500152
55748650	55748673	12	+	28162770	SKM1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.5886306221368373	[81]	[217]	5	hSpCas9	negative selection	10500153
55748712	55748735	12	-	28162770	SKM1	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.31727309058012226	[73]	[162]	3	hSpCas9	negative selection	10500154
55748734	55748757	12	+	28162770	SKM1	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.3573334310185611	[49]	[68]	-3	hSpCas9	negative selection	10500155
55743638	55743661	12	-	28162770	SKM1	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.09367502212967208	[66]	[110]	-1	hSpCas9	negative selection	10500156
55743604	55743627	12	-	28162770	SKM1	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.016088750138307795	[142]	[249]	0	hSpCas9	negative selection	10669513
55743726	55743749	12	-	28162770	SKM1	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.8220016980220055	[19]	[9]	-8	hSpCas9	negative selection	10669514
55743688	55743711	12	+	28162770	SKM1	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.0820645373245084	[96]	[80]	-7	hSpCas9	negative selection	10669515
55743502	55743525	12	-	28162770	SKM1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	1.6030198898294605	[53]	[289]	9	hSpCas9	negative selection	10669516
55743592	55743615	12	+	28162770	SKM1	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.12286817738153799	[84]	[137]	-1	hSpCas9	negative selection	10669517
55743330	55743353	12	-	28162770	SKM1	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.0259952085329445	[24]	[89]	8	hSpCas9	negative selection	10669518
55748650	55748673	12	+	28162770	SKM1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.5886306221368373	[81]	[217]	5	hSpCas9	negative selection	10669519
55748712	55748735	12	-	28162770	SKM1	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.31727309058012226	[73]	[162]	3	hSpCas9	negative selection	10669520
55748734	55748757	12	+	28162770	SKM1	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.3573334310185611	[49]	[68]	-3	hSpCas9	negative selection	10669521
55743638	55743661	12	-	28162770	SKM1	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.09367502212967208	[66]	[110]	-1	hSpCas9	negative selection	10669522
55743604	55743627	12	-	28162770	PL21	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.27340160356341303	[410]	[147]	-2	hSpCas9	negative selection	10838879
55743726	55743749	12	-	28162770	PL21	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	0.09051512331482225	[40]	[18]	0	hSpCas9	negative selection	10838880
55743688	55743711	12	+	28162770	PL21	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-0.9281844824862194	[375]	[85]	-6	hSpCas9	negative selection	10838881
55743502	55743525	12	-	28162770	PL21	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.5665032670324743	[210]	[135]	5	hSpCas9	negative selection	10838882
55743592	55743615	12	+	28162770	PL21	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.8782115196019579	[269]	[215]	7	hSpCas9	negative selection	10838883
55743330	55743353	12	-	28162770	PL21	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.6584303117220478	[114]	[78]	5	hSpCas9	negative selection	10838884
55748650	55748673	12	+	28162770	PL21	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.12324601494916809	[288]	[136]	1	hSpCas9	negative selection	10838885
55748712	55748735	12	-	28162770	PL21	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	-0.17398469152347074	[196]	[75]	-1	hSpCas9	negative selection	10838886
55748734	55748757	12	+	28162770	PL21	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.42720852303524137	[175]	[102]	4	hSpCas9	negative selection	10838887
55743638	55743661	12	-	28162770	PL21	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.08971562479566969	[189]	[87]	0	hSpCas9	negative selection	10838888
55743604	55743627	12	-	28162770	P31FUJ	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.38017467247637415	[526]	[805]	4	hSpCas9	negative selection	11008245
55743726	55743749	12	-	28162770	P31FUJ	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-0.9406214529210682	[146]	[89]	-6	hSpCas9	negative selection	11008246
55743688	55743711	12	+	28162770	P31FUJ	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.545238850324443	[302]	[60]	-8	hSpCas9	negative selection	11008247
55743502	55743525	12	-	28162770	P31FUJ	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.3477379712590385	[221]	[204]	-3	hSpCas9	negative selection	11008248
55743592	55743615	12	+	28162770	P31FUJ	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.21362989513953268	[298]	[302]	-2	hSpCas9	negative selection	11008249
55743330	55743353	12	-	28162770	P31FUJ	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.8128404611413338	[139]	[288]	8	hSpCas9	negative selection	11008250
55748650	55748673	12	+	28162770	P31FUJ	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.2375401234210418	[304]	[303]	-2	hSpCas9	negative selection	11008251
55748712	55748735	12	-	28162770	P31FUJ	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	-0.04962110626979943	[324]	[368]	0	hSpCas9	negative selection	11008252
55748734	55748757	12	+	28162770	P31FUJ	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.17372379500894783	[254]	[337]	1	hSpCas9	negative selection	11008253
55743638	55743661	12	-	28162770	P31FUJ	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.2991255339849094	[313]	[453]	3	hSpCas9	negative selection	11008254
55743604	55743627	12	-	28162770	OCIAML5	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.6865136789992994	[294]	[856]	6	hSpCas9	negative selection	11177611
55743726	55743749	12	-	28162770	OCIAML5	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	0.010429905386068139	[43]	[79]	0	hSpCas9	negative selection	11177612
55743688	55743711	12	+	28162770	OCIAML5	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.04708255326914	[173]	[75]	-8	hSpCas9	negative selection	11177613
55743502	55743525	12	-	28162770	OCIAML5	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.1680176751793354	[106]	[216]	1	hSpCas9	negative selection	11177614
55743592	55743615	12	+	28162770	OCIAML5	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.2984250556634537	[190]	[423]	2	hSpCas9	negative selection	11177615
55743330	55743353	12	-	28162770	OCIAML5	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	-0.5729124996669261	[88]	[107]	-4	hSpCas9	negative selection	11177616
55748650	55748673	12	+	28162770	OCIAML5	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.49688173795707447	[200]	[511]	4	hSpCas9	negative selection	11177617
55748712	55748735	12	-	28162770	OCIAML5	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.11510203666863073	[199]	[390]	0	hSpCas9	negative selection	11177618
55748734	55748757	12	+	28162770	OCIAML5	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.9018196060610967	[117]	[113]	-5	hSpCas9	negative selection	11177619
55743638	55743661	12	-	28162770	OCIAML5	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.05086601117583828	[145]	[272]	0	hSpCas9	negative selection	11177620
55743604	55743627	12	-	28162770	EOL1	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.06803069847713528	[984]	[543]	0	hSpCas9	negative selection	11346977
55743726	55743749	12	-	28162770	EOL1	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	1.047404519356068	[44]	[48]	8	hSpCas9	negative selection	11346978
55743688	55743711	12	+	28162770	EOL1	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-3.0217240420119498	[816]	[52]	-9	hSpCas9	negative selection	11346979
55743502	55743525	12	-	28162770	EOL1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.5387880648139366	[438]	[335]	5	hSpCas9	negative selection	11346980
55743592	55743615	12	+	28162770	EOL1	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.06995624067461326	[523]	[262]	0	hSpCas9	negative selection	11346981
55743330	55743353	12	-	28162770	EOL1	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.48342104342303	[185]	[273]	9	hSpCas9	negative selection	11346982
55748650	55748673	12	+	28162770	EOL1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.08195566945638888	[372]	[207]	0	hSpCas9	negative selection	11346983
55748712	55748735	12	-	28162770	EOL1	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.015313235493716798	[307]	[163]	0	hSpCas9	negative selection	11346984
55748734	55748757	12	+	28162770	EOL1	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-1.751562617208817	[293]	[45]	-8	hSpCas9	negative selection	11346985
55743638	55743661	12	-	28162770	EOL1	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.5095102722916907	[251]	[188]	4	hSpCas9	negative selection	11346986
55743604	55743627	12	-	28162770	MOLM13	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.13880695746919058	[656]	[522]	1	hSpCas9	negative selection	11516343
55743726	55743749	12	-	28162770	MOLM13	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.8896626230735047	[81]	[15]	-7	hSpCas9	negative selection	11516344
55743688	55743711	12	+	28162770	MOLM13	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.704391040895863	[612]	[67]	-8	hSpCas9	negative selection	11516345
55743502	55743525	12	-	28162770	MOLM13	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	1.1383212244550842	[283]	[451]	8	hSpCas9	negative selection	11516346
55743592	55743615	12	+	28162770	MOLM13	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.6717617149102287	[447]	[515]	5	hSpCas9	negative selection	11516347
55743330	55743353	12	-	28162770	MOLM13	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.9922255233142342	[161]	[232]	7	hSpCas9	negative selection	11516348
55748650	55748673	12	+	28162770	MOLM13	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.7268222990157555	[498]	[217]	-4	hSpCas9	negative selection	11516349
55748712	55748735	12	-	28162770	MOLM13	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.19007692033950563	[313]	[258]	1	hSpCas9	negative selection	11516350
55748734	55748757	12	+	28162770	MOLM13	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.12698858804165997	[218]	[144]	-1	hSpCas9	negative selection	11516351
55743638	55743661	12	-	28162770	MOLM13	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.23342412790755598	[319]	[271]	1	hSpCas9	negative selection	11516352
55743604	55743627	12	-	28162770	HEL	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.5700697643021244	[569]	[541]	5	hSpCas9	negative selection	11685709
55743726	55743749	12	-	28162770	HEL	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.2577254944487288	[55]	[14]	-6	hSpCas9	negative selection	11685710
55743688	55743711	12	+	28162770	HEL	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-2.5334587664574855	[460]	[50]	-8	hSpCas9	negative selection	11685711
55743502	55743525	12	-	28162770	HEL	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.6668244505246701	[296]	[301]	6	hSpCas9	negative selection	11685712
55743592	55743615	12	+	28162770	HEL	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.26632262674882057	[343]	[264]	2	hSpCas9	negative selection	11685713
55743330	55743353	12	-	28162770	HEL	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.4590268788279688	[183]	[161]	4	hSpCas9	negative selection	11685714
55748650	55748673	12	+	28162770	HEL	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.05717977541052921	[345]	[212]	0	hSpCas9	negative selection	11685715
55748712	55748735	12	-	28162770	HEL	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	1.2113625959067655	[295]	[438]	9	hSpCas9	negative selection	11685716
55748734	55748757	12	+	28162770	HEL	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.5722740589704933	[194]	[83]	-4	hSpCas9	negative selection	11685717
55743638	55743661	12	-	28162770	HEL	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.9422236687207992	[251]	[83]	-5	hSpCas9	negative selection	11685718
55743604	55743627	12	-	28162770	MV411	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.6252421438626437	[470]	[611]	5	hSpCas9	negative selection	11855075
55743726	55743749	12	-	28162770	MV411	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	1.5970219885730028	[30]	[78]	9	hSpCas9	negative selection	11855076
55743688	55743711	12	+	28162770	MV411	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.7574282043890408	[296]	[73]	-8	hSpCas9	negative selection	11855077
55743502	55743525	12	-	28162770	MV411	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.9972414502782209	[178]	[300]	8	hSpCas9	negative selection	11855078
55743592	55743615	12	+	28162770	MV411	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.48952804338343087	[234]	[140]	-4	hSpCas9	negative selection	11855079
55743330	55743353	12	-	28162770	MV411	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.8324000515039316	[91]	[137]	7	hSpCas9	negative selection	11855080
55748650	55748673	12	+	28162770	MV411	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	0.821276673032221	[216]	[322]	7	hSpCas9	negative selection	11855081
55748712	55748735	12	-	28162770	MV411	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.32629297149401504	[266]	[281]	3	hSpCas9	negative selection	11855082
55748734	55748757	12	+	28162770	MV411	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-1.2905274704012113	[150]	[51]	-7	hSpCas9	negative selection	11855083
55743638	55743661	12	-	28162770	MV411	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.38727798513548045	[235]	[151]	-3	hSpCas9	negative selection	11855084
55743604	55743627	12	-	28162770	MONOMAC1	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.040002350241295725	[223]	[263]	0	hSpCas9	negative selection	12024441
55743726	55743749	12	-	28162770	MONOMAC1	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	1.1854327897628592	[27]	[72]	8	hSpCas9	negative selection	12024442
55743688	55743711	12	+	28162770	MONOMAC1	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.5161608690702133	[256]	[102]	-8	hSpCas9	negative selection	12024443
55743502	55743525	12	-	28162770	MONOMAC1	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.2470775295591492	[175]	[169]	-2	hSpCas9	negative selection	12024444
55743592	55743615	12	+	28162770	MONOMAC1	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.5972773444103168	[193]	[146]	-5	hSpCas9	negative selection	12024445
55743330	55743353	12	-	28162770	MONOMAC1	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.5902338289547181	[61]	[106]	6	hSpCas9	negative selection	12024446
55748650	55748673	12	+	28162770	MONOMAC1	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	1.655667062172924	[169]	[613]	9	hSpCas9	negative selection	12024447
55748712	55748735	12	-	28162770	MONOMAC1	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.42329998376348776	[187]	[288]	4	hSpCas9	negative selection	12024448
55748734	55748757	12	+	28162770	MONOMAC1	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	0.675957876205126	[88]	[162]	6	hSpCas9	negative selection	12024449
55743638	55743661	12	-	28162770	MONOMAC1	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.6657123099404707	[136]	[98]	-5	hSpCas9	negative selection	12024450
55743604	55743627	12	-	28162770	OCIAML2	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	0.4324084448707508	[99]	[747]	4	hSpCas9	negative selection	12193807
55743726	55743749	12	-	28162770	OCIAML2	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	-1.1811232080471763	[8]	[21]	-6	hSpCas9	negative selection	12193808
55743688	55743711	12	+	28162770	OCIAML2	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.9731301657713445	[67]	[95]	-8	hSpCas9	negative selection	12193809
55743502	55743525	12	-	28162770	OCIAML2	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	-0.15721323021031627	[33]	[168]	-1	hSpCas9	negative selection	12193810
55743592	55743615	12	+	28162770	OCIAML2	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	0.9923421511003847	[36]	[407]	8	hSpCas9	negative selection	12193811
55743330	55743353	12	-	28162770	OCIAML2	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	1.2842576769213074	[11]	[161]	9	hSpCas9	negative selection	12193812
55748650	55748673	12	+	28162770	OCIAML2	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.22025499137983284	[61]	[294]	-2	hSpCas9	negative selection	12193813
55748712	55748735	12	-	28162770	OCIAML2	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.2549008738617614	[56]	[376]	2	hSpCas9	negative selection	12193814
55748734	55748757	12	+	28162770	OCIAML2	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.7105806179629138	[30]	[104]	-5	hSpCas9	negative selection	12193815
55743638	55743661	12	-	28162770	OCIAML2	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	-0.6475075873262406	[51]	[183]	-5	hSpCas9	negative selection	12193816
55743604	55743627	12	-	28162770	OCIAML3	viability	GCAGCTGCTTCACCACCTCGCGG	GDF11	ENSG00000135414	-0.006042651441483526	[159]	[480]	0	hSpCas9	negative selection	12363173
55743726	55743749	12	-	28162770	OCIAML3	viability	GCTAATGACGGTCTCGGTGGTGG	GDF11	ENSG00000135414	1.0498485494505616	[7]	[49]	8	hSpCas9	negative selection	12363174
55743688	55743711	12	+	28162770	OCIAML3	viability	GCAGCCCGAGGACTTCCTGGAGG	GDF11	ENSG00000135414	-1.0438105577636836	[83]	[122]	-6	hSpCas9	negative selection	12363175
55743502	55743525	12	-	28162770	OCIAML3	viability	GCTGCCGCCAAACGCACACGGGG	GDF11	ENSG00000135414	0.5257316039499325	[51]	[225]	5	hSpCas9	negative selection	12363176
55743592	55743615	12	+	28162770	OCIAML3	viability	GCCCAACATCAGCCGCGAGGTGG	GDF11	ENSG00000135414	-0.2755601141717628	[82]	[206]	-2	hSpCas9	negative selection	12363177
55743330	55743353	12	-	28162770	OCIAML3	viability	CAGGAAGCCCAGCAGCAGCGGGG	GDF11	ENSG00000135414	0.9989476511505239	[29]	[180]	8	hSpCas9	negative selection	12363178
55748650	55748673	12	+	28162770	OCIAML3	viability	GATGTTCACAAAGGTACTGAAGG	GDF11	ENSG00000135414	-0.009045139603007069	[57]	[173]	0	hSpCas9	negative selection	12363179
55748712	55748735	12	-	28162770	OCIAML3	viability	CAAGATCTGCAGGTAGACTGTGG	GDF11	ENSG00000135414	0.933469365736233	[63]	[368]	7	hSpCas9	negative selection	12363180
55748734	55748757	12	+	28162770	OCIAML3	viability	GCGACTAAAACCCCTAACTGGGG	GDF11	ENSG00000135414	-0.7804207645550445	[32]	[57]	-5	hSpCas9	negative selection	12363181
55743638	55743661	12	-	28162770	OCIAML3	viability	TCCAGGATCTGCTGCAGCGGCGG	GDF11	ENSG00000135414	0.14725809127566847	[66]	[223]	1	hSpCas9	negative selection	12363182