Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 2911
• Symbol: GRM1
• Description: glutamate metabotropic receptor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/GRM1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
146399003	146399026	6	-	26472758	Jiyoye	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-1.3127166993013915	[55]	[16]	-7	hSpCas9	negative selection	67447
146399147	146399170	6	-	26472758	Jiyoye	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-3.51882403705035	[227]	[14]	-9	hSpCas9	negative selection	67448
146029733	146029756	6	+	26472758	Jiyoye	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.6522878793424048	[107]	[127]	5	hSpCas9	negative selection	67449
146159380	146159403	6	+	26472758	Jiyoye	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	2.3997958511402757	[48]	[194]	9	hSpCas9	negative selection	67450
146159424	146159447	6	+	26472758	Jiyoye	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-0.1345339212613989	[114]	[78]	-1	hSpCas9	negative selection	67451
146304730	146304753	6	+	26472758	Jiyoye	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	1.0695423859126363	[126]	[200]	7	hSpCas9	negative selection	67452
146386972	146386995	6	+	26472758	Jiyoye	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.2879700369657059	[33]	[20]	-2	hSpCas9	negative selection	67453
146398884	146398907	6	+	26472758	Jiyoye	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.9376900982046532	[17]	[25]	6	hSpCas9	negative selection	67454
146398913	146398936	6	-	26472758	Jiyoye	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.689318610287372	[124]	[151]	5	hSpCas9	negative selection	67455
146398956	146398979	6	-	26472758	Jiyoye	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.2771148409415005	[289]	[264]	2	hSpCas9	negative selection	67456
146399003	146399026	6	-	26472758	KBM7	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-1.6497533862942513	[252,206]	[28,38]	-8	hSpCas9	negative selection	258565
146399147	146399170	6	-	26472758	KBM7	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-3.397175308282091	[490,497]	[27,16]	-9	hSpCas9	negative selection	258566
146029733	146029756	6	+	26472758	KBM7	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	-0.10970175402172394	[534,305]	[187,170]	-1	hSpCas9	negative selection	258567
146159380	146159403	6	+	26472758	KBM7	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.8100275860559811	[599,615]	[705,323]	8	hSpCas9	negative selection	258568
146159424	146159447	6	+	26472758	KBM7	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-0.44773352338747674	[317,273]	[143,63]	-4	hSpCas9	negative selection	258569
146304730	146304753	6	+	26472758	KBM7	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.8630845090441938	[567,522]	[554,387]	8	hSpCas9	negative selection	258570
146386972	146386995	6	+	26472758	KBM7	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.3479570691685496	[177,165]	[80,317]	9	hSpCas9	negative selection	258571
146398884	146398907	6	+	26472758	KBM7	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.9812751315312462	[186,152]	[204,113]	9	hSpCas9	negative selection	258572
146398913	146398936	6	-	26472758	KBM7	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	-0.24379419762945329	[824,457]	[285,214]	-2	hSpCas9	negative selection	258573
146398956	146398979	6	-	26472758	KBM7	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.19695704100979028	[1436,1268]	[583,856]	2	hSpCas9	negative selection	258574
146399003	146399026	6	-	26472758	Raji	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-2.869896388126317	[62]	[1]	-9	hSpCas9	negative selection	449683
146399147	146399170	6	-	26472758	Raji	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-3.6792128265172073	[275]	[4]	-9	hSpCas9	negative selection	449684
146029733	146029756	6	+	26472758	Raji	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.12508553710705855	[161]	[40]	1	hSpCas9	negative selection	449685
146159380	146159403	6	+	26472758	Raji	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.0944056813753894	[334]	[82]	0	hSpCas9	negative selection	449686
146159424	146159447	6	+	26472758	Raji	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.18400481697651183	[109]	[28]	1	hSpCas9	negative selection	449687
146304730	146304753	6	+	26472758	Raji	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	1.414812060565847	[159]	[98]	9	hSpCas9	negative selection	449688
146386972	146386995	6	+	26472758	Raji	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.705285091802254	[110]	[41]	6	hSpCas9	negative selection	449689
146398884	146398907	6	+	26472758	Raji	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-0.21454455951376272	[109]	[21]	-2	hSpCas9	negative selection	449690
146398913	146398936	6	-	26472758	Raji	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.4641758936164897	[277]	[88]	4	hSpCas9	negative selection	449691
146398956	146398979	6	-	26472758	Raji	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.3329272001189525	[786]	[144]	-3	hSpCas9	negative selection	449692
146399003	146399026	6	-	26472758	K562	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-4.528170776230481	[81]	[2]	-9	hSpCas9	negative selection	640801
146399147	146399170	6	-	26472758	K562	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-8.340543773054709	[383]	[0]	-9	hSpCas9	negative selection	640802
146029733	146029756	6	+	26472758	K562	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.4923462411100323	[255]	[303]	4	hSpCas9	negative selection	640803
146159380	146159403	6	+	26472758	K562	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.2308863143595965	[481]	[954]	9	hSpCas9	negative selection	640804
146159424	146159447	6	+	26472758	K562	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.13194399840803417	[239]	[221]	1	hSpCas9	negative selection	640805
146304730	146304753	6	+	26472758	K562	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.6516956109165413	[465]	[617]	5	hSpCas9	negative selection	640806
146386972	146386995	6	+	26472758	K562	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.6208709634752988	[234]	[128]	-4	hSpCas9	negative selection	640807
146398884	146398907	6	+	26472758	K562	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-0.3211784481877782	[110]	[74]	-2	hSpCas9	negative selection	640808
146398913	146398936	6	-	26472758	K562	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.3544931190662798	[390]	[421]	2	hSpCas9	negative selection	640809
146398956	146398979	6	-	26472758	K562	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.12736022686793924	[1064]	[981]	0	hSpCas9	negative selection	640810
146029682	146029705	6	-	26627737	DLD1	viability	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	-0.0024726846606477615	[80]	[23,3,43]	0	hSpCas9	negative selection	830837
146159403	146159426	6	-	26627737	DLD1	viability	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.3105010255049534	[1035]	[535,373,307]	3	hSpCas9	negative selection	830838
146304788	146304811	6	-	26627737	DLD1	viability	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.38467740886799184	[207]	[7,35,191]	4	hSpCas9	negative selection	830839
146352365	146352388	6	-	26627737	DLD1	viability	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-0.08442917985359877	[30]	[8,0,15]	-1	hSpCas9	negative selection	830840
146357570	146357593	6	+	26627737	DLD1	viability	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.28031067483290517	[966]	[267,357,141]	-3	hSpCas9	negative selection	830841
146386972	146386995	6	+	26627737	DLD1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.9746419486528344	[320]	[266,133,188]	8	hSpCas9	negative selection	830842
146029682	146029705	6	-	26627737	GBM cells	viability after 5 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.6358794690518916	[74]	[73,50]	8	hSpCas9	negative selection	913152
146159403	146159426	6	-	26627737	GBM cells	viability after 5 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.15360263230529947	[548]	[382,271]	2	hSpCas9	negative selection	913153
146304788	146304811	6	-	26627737	GBM cells	viability after 5 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.4450405263316759	[65]	[19,31]	-6	hSpCas9	negative selection	913154
146352365	146352388	6	-	26627737	GBM cells	viability after 5 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.17193236929210176	[23]	[19,8]	2	hSpCas9	negative selection	913155
146357570	146357593	6	+	26627737	GBM cells	viability after 5 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.21031519486907274	[383]	[159,195]	-3	hSpCas9	negative selection	913156
146386972	146386995	6	+	26627737	GBM cells	viability after 5 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.483876375606842	[253]	[190,189]	7	hSpCas9	negative selection	913157
146029682	146029705	6	-	26627737	GBM cells	viability after 13 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.939638342624967	[74]	[114,47]	9	hSpCas9	negative selection	995467
146159403	146159426	6	-	26627737	GBM cells	viability after 13 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.18404535128566324	[548]	[392,293]	2	hSpCas9	negative selection	995468
146304788	146304811	6	-	26627737	GBM cells	viability after 13 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.37438843638857455	[65]	[36,19]	-4	hSpCas9	negative selection	995469
146352365	146352388	6	-	26627737	GBM cells	viability after 13 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-0.6004976595130307	[23]	[12,4]	-6	hSpCas9	negative selection	995470
146357570	146357593	6	+	26627737	GBM cells	viability after 13 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.055242235451827604	[383]	[210,191]	0	hSpCas9	negative selection	995471
146386972	146386995	6	+	26627737	GBM cells	viability after 13 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.2958662586938563	[253]	[387,297]	9	hSpCas9	negative selection	995472
146029682	146029705	6	-	26627737	GBM cells	viability after 21 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.5902753985820419	[74]	[64,57]	6	hSpCas9	negative selection	1077782
146159403	146159426	6	-	26627737	GBM cells	viability after 21 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.15248437570422846	[548]	[342,320]	1	hSpCas9	negative selection	1077783
146304788	146304811	6	-	26627737	GBM cells	viability after 21 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.19197876388255763	[65]	[33,28]	-2	hSpCas9	negative selection	1077784
146352365	146352388	6	-	26627737	GBM cells	viability after 21 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-2.3956823975148676	[23]	[2,1]	-9	hSpCas9	negative selection	1077785
146357570	146357593	6	+	26627737	GBM cells	viability after 21 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.27427664943996627	[383]	[195,150]	-3	hSpCas9	negative selection	1077786
146386972	146386995	6	+	26627737	GBM cells	viability after 21 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.2958859903994553	[253]	[354,323]	9	hSpCas9	negative selection	1077787
146029682	146029705	6	-	26627737	RPE1	viability after 9 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	1.5440148794838877	[180]	[128,211]	8	hSpCas9	negative selection	1160097
146159403	146159426	6	-	26627737	RPE1	viability after 9 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.13733555812572307	[1236]	[273,621]	1	hSpCas9	negative selection	1160098
146304788	146304811	6	-	26627737	RPE1	viability after 9 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.07179173571951436	[278]	[86,97]	0	hSpCas9	negative selection	1160099
146352365	146352388	6	-	26627737	RPE1	viability after 9 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	1.1321416389417451	[24]	[0,37]	7	hSpCas9	negative selection	1160100
146357570	146357593	6	+	26627737	RPE1	viability after 9 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.1589153401692719	[1104]	[425,159]	-1	hSpCas9	negative selection	1160101
146386972	146386995	6	+	26627737	RPE1	viability after 9 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.400551521385856	[534]	[284,644]	7	hSpCas9	negative selection	1160102
146029682	146029705	6	-	26627737	RPE1	viability after 12 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	1.9946902851176511	[180]	[84,308]	8	hSpCas9	negative selection	1242412
146159403	146159426	6	-	26627737	RPE1	viability after 12 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.7886039720883662	[1236]	[474,678]	5	hSpCas9	negative selection	1242413
146304788	146304811	6	-	26627737	RPE1	viability after 12 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.6359993243875314	[278]	[98,134]	4	hSpCas9	negative selection	1242414
146352365	146352388	6	-	26627737	RPE1	viability after 12 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.6737189903366891	[24]	[0,20]	4	hSpCas9	negative selection	1242415
146357570	146357593	6	+	26627737	RPE1	viability after 12 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.3438830795553256	[1104]	[332,128]	-2	hSpCas9	negative selection	1242416
146386972	146386995	6	+	26627737	RPE1	viability after 12 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.409281656948608	[534]	[322,443]	7	hSpCas9	negative selection	1242417
146029682	146029705	6	-	26627737	RPE1	viability after 15 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	3.037469049206864	[180]	[229,603]	9	hSpCas9	negative selection	1324727
146159403	146159426	6	-	26627737	RPE1	viability after 15 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.7492188010838983	[1236]	[493,678]	4	hSpCas9	negative selection	1324728
146304788	146304811	6	-	26627737	RPE1	viability after 15 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.5592591308811372	[278]	[21,83]	-4	hSpCas9	negative selection	1324729
146352365	146352388	6	-	26627737	RPE1	viability after 15 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.4489965199068493	[24]	[0,17]	3	hSpCas9	negative selection	1324730
146357570	146357593	6	+	26627737	RPE1	viability after 15 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.3996002274053416	[1104]	[379,98]	-3	hSpCas9	negative selection	1324731
146386972	146386995	6	+	26627737	RPE1	viability after 15 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.01294424464734	[534]	[169,435]	6	hSpCas9	negative selection	1324732
146029682	146029705	6	-	26627737	RPE1	viability after 18 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	3.6568197926629806	[180]	[166,1095]	9	hSpCas9	negative selection	1407042
146159403	146159426	6	-	26627737	RPE1	viability after 18 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	1.1024958261558835	[1236]	[623,815]	6	hSpCas9	negative selection	1407043
146304788	146304811	6	-	26627737	RPE1	viability after 18 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.6098697922488505	[278]	[29,69]	-4	hSpCas9	negative selection	1407044
146352365	146352388	6	-	26627737	RPE1	viability after 18 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	1.5037807530993423	[24]	[22,14]	7	hSpCas9	negative selection	1407045
146357570	146357593	6	+	26627737	RPE1	viability after 18 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.3272132022854968	[1104]	[286,184]	-2	hSpCas9	negative selection	1407046
146386972	146386995	6	+	26627737	RPE1	viability after 18 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.9595554205673011	[534]	[215,349]	6	hSpCas9	negative selection	1407047
146029682	146029705	6	-	26627737	HeLa	viability after 8 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	2.3763272993642968	[49]	[125,135,81]	9	hSpCas9	negative selection	1489357
146159403	146159426	6	-	26627737	HeLa	viability after 8 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.5290781103111843	[577]	[567,307,264]	5	hSpCas9	negative selection	1489358
146304788	146304811	6	-	26627737	HeLa	viability after 8 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.36972361272757337	[80]	[91,55,1]	3	hSpCas9	negative selection	1489359
146352365	146352388	6	-	26627737	HeLa	viability after 8 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-3.313522659538349	[98]	[0,2,7]	-9	hSpCas9	negative selection	1489360
146357570	146357593	6	+	26627737	HeLa	viability after 8 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.2993055462882294	[681]	[219,200,293]	-3	hSpCas9	negative selection	1489361
146386972	146386995	6	+	26627737	HeLa	viability after 8 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-1.1032602446928594	[484]	[123,131,47]	-8	hSpCas9	negative selection	1489362
146029682	146029705	6	-	26627737	HeLa	viability after 12 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	1.96845710862124	[49]	[40,84,114]	9	hSpCas9	negative selection	1571672
146159403	146159426	6	-	26627737	HeLa	viability after 12 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.5694243020911802	[577]	[581,278,216]	5	hSpCas9	negative selection	1571673
146304788	146304811	6	-	26627737	HeLa	viability after 12 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	1.1486698207361166	[80]	[0,97,118]	8	hSpCas9	negative selection	1571674
146352365	146352388	6	-	26627737	HeLa	viability after 12 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-1.531028476107035	[98]	[0,14,25]	-8	hSpCas9	negative selection	1571675
146357570	146357593	6	+	26627737	HeLa	viability after 12 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.18777524566610904	[681]	[225,225,291]	-2	hSpCas9	negative selection	1571676
146386972	146386995	6	+	26627737	HeLa	viability after 12 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.454608499193126	[484]	[259,336,219]	4	hSpCas9	negative selection	1571677
146029682	146029705	6	-	26627737	HeLa	viability after 15 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	2.4973731056240447	[49]	[49,103,197]	9	hSpCas9	negative selection	1653987
146159403	146159426	6	-	26627737	HeLa	viability after 15 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.0881209418363138	[577]	[265,211,273]	0	hSpCas9	negative selection	1653988
146304788	146304811	6	-	26627737	HeLa	viability after 15 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	1.5851118649854181	[80]	[94,64,139]	9	hSpCas9	negative selection	1653989
146352365	146352388	6	-	26627737	HeLa	viability after 15 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-5.332823507771604	[98]	[0,0,0]	-9	hSpCas9	negative selection	1653990
146357570	146357593	6	+	26627737	HeLa	viability after 15 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.2559194977038489	[681]	[214,174,313]	-2	hSpCas9	negative selection	1653991
146386972	146386995	6	+	26627737	HeLa	viability after 15 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.5861208622030651	[484]	[225,332,333]	5	hSpCas9	negative selection	1653992
146029682	146029705	6	-	26627737	HeLa	viability after 18 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	2.478928479327898	[49]	[33,81,197]	9	hSpCas9	negative selection	1736302
146159403	146159426	6	-	26627737	HeLa	viability after 18 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.06928620059526536	[577]	[174,171,273]	0	hSpCas9	negative selection	1736303
146304788	146304811	6	-	26627737	HeLa	viability after 18 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	1.5806124348683306	[80]	[62,53,139]	8	hSpCas9	negative selection	1736304
146352365	146352388	6	-	26627737	HeLa	viability after 18 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-5.022617856117737	[98]	[0,0,0]	-9	hSpCas9	negative selection	1736305
146357570	146357593	6	+	26627737	HeLa	viability after 18 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	-0.29072792274749537	[681]	[134,142,313]	-3	hSpCas9	negative selection	1736306
146386972	146386995	6	+	26627737	HeLa	viability after 18 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.5825514714460094	[484]	[153,270,333]	5	hSpCas9	negative selection	1736307
146029682	146029705	6	-	26627737	HCT116	viability after 6 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	-2.440881222265517	[164]	[7,2]	-8	hSpCas9	negative selection	1818617
146159403	146159426	6	-	26627737	HCT116	viability after 6 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.2864424089413069	[1953]	[208,465]	1	hSpCas9	negative selection	1818618
146304788	146304811	6	-	26627737	HCT116	viability after 6 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-2.6512409509445636	[181]	[10,0]	-9	hSpCas9	negative selection	1818619
146352365	146352388	6	-	26627737	HCT116	viability after 6 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-2.4182025840627723	[33]	[0,0]	-8	hSpCas9	negative selection	1818620
146357570	146357593	6	+	26627737	HCT116	viability after 6 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.407794448539012	[649]	[83,163]	2	hSpCas9	negative selection	1818621
146386972	146386995	6	+	26627737	HCT116	viability after 6 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.627920513855363	[528]	[82,352]	8	hSpCas9	negative selection	1818622
146029682	146029705	6	-	26627737	HCT116	viability after 8 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.5933947378207634	[90]	[76,74,74]	6	hSpCas9	negative selection	1900932
146159403	146159426	6	-	26627737	HCT116	viability after 8 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	-0.0820760467190298	[652]	[378,345,295]	-1	hSpCas9	negative selection	1900933
146304788	146304811	6	-	26627737	HCT116	viability after 8 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.4024275619817508	[122]	[60,40,51]	-5	hSpCas9	negative selection	1900934
146352365	146352388	6	-	26627737	HCT116	viability after 8 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	1.023697526329065	[21]	[19,40,12]	8	hSpCas9	negative selection	1900935
146357570	146357593	6	+	26627737	HCT116	viability after 8 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.4698299910412682	[315]	[280,187,254]	5	hSpCas9	negative selection	1900936
146386972	146386995	6	+	26627737	HCT116	viability after 8 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.6503717749529185	[220]	[169,208,193]	6	hSpCas9	negative selection	1900937
146029682	146029705	6	-	26627737	HCT116	viability after 9 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.7100360154196337	[164]	[161,0]	5	hSpCas9	negative selection	1983247
146159403	146159426	6	-	26627737	HCT116	viability after 9 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	-0.8306062007413598	[1953]	[346,250]	-5	hSpCas9	negative selection	1983248
146304788	146304811	6	-	26627737	HCT116	viability after 9 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	1.2953948064992462	[181]	[25,192]	8	hSpCas9	negative selection	1983249
146352365	146352388	6	-	26627737	HCT116	viability after 9 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-0.1711450240953587	[33]	[16,0]	-1	hSpCas9	negative selection	1983250
146357570	146357593	6	+	26627737	HCT116	viability after 9 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.7837824381969604	[649]	[395,221]	5	hSpCas9	negative selection	1983251
146386972	146386995	6	+	26627737	HCT116	viability after 9 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.6181288103946696	[528]	[546,343]	8	hSpCas9	negative selection	1983252
146029682	146029705	6	-	26627737	HCT116	viability after 12 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.8065005300695681	[90]	[41,100,111]	7	hSpCas9	negative selection	2065562
146159403	146159426	6	-	26627737	HCT116	viability after 12 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	-0.012060192676219827	[652]	[239,391,398]	0	hSpCas9	negative selection	2065563
146304788	146304811	6	-	26627737	HCT116	viability after 12 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.02366397301418144	[122]	[99,60,32]	0	hSpCas9	negative selection	2065564
146352365	146352388	6	-	26627737	HCT116	viability after 12 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-0.9917115110945551	[21]	[1,14,0]	-8	hSpCas9	negative selection	2065565
146357570	146357593	6	+	26627737	HCT116	viability after 12 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.649599155944597	[315]	[242,215,322]	6	hSpCas9	negative selection	2065566
146386972	146386995	6	+	26627737	HCT116	viability after 12 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.48542145697691685	[220]	[102,243,147]	5	hSpCas9	negative selection	2065567
146029682	146029705	6	-	26627737	HCT116	viability after 15 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.19921346132110895	[90]	[50,75,51]	2	hSpCas9	negative selection	2147877
146159403	146159426	6	-	26627737	HCT116	viability after 15 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	-0.020955544378149282	[652]	[405,399,307]	0	hSpCas9	negative selection	2147878
146304788	146304811	6	-	26627737	HCT116	viability after 15 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.46702274572894176	[122]	[77,61,16]	-5	hSpCas9	negative selection	2147879
146352365	146352388	6	-	26627737	HCT116	viability after 15 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.21226928048487181	[21]	[14,17,10]	2	hSpCas9	negative selection	2147880
146357570	146357593	6	+	26627737	HCT116	viability after 15 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.45346064969253186	[315]	[276,308,163]	4	hSpCas9	negative selection	2147881
146386972	146386995	6	+	26627737	HCT116	viability after 15 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.0900280951625176	[220]	[241,201,361]	8	hSpCas9	negative selection	2147882
146029682	146029705	6	-	26627737	HCT116	viability after 18 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	-0.14083683222217647	[90]	[42,18,59]	-1	hSpCas9	negative selection	2230192
146159403	146159426	6	-	26627737	HCT116	viability after 18 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.17636379165298455	[652]	[357,460,238]	1	hSpCas9	negative selection	2230193
146304788	146304811	6	-	26627737	HCT116	viability after 18 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.4686082436511849	[122]	[60,51,13]	-4	hSpCas9	negative selection	2230194
146352365	146352388	6	-	26627737	HCT116	viability after 18 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.5128374682448991	[21]	[11,20,11]	4	hSpCas9	negative selection	2230195
146357570	146357593	6	+	26627737	HCT116	viability after 18 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	1.2263205910689945	[315]	[398,265,415]	8	hSpCas9	negative selection	2230196
146386972	146386995	6	+	26627737	HCT116	viability after 18 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.1731465448500238	[220]	[95,195,442]	8	hSpCas9	negative selection	2230197
146029047	146029070	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	AACAGCTTGGAGCGCAGCTGTGG	GRM1	ENSG00000152822	2.9153840764901893	[87,11]	[24,144]	8	dCas9-VP64	positive selection	2419558
146029070	146029093	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACATCCTGATATCGGCTGCAGG	GRM1	ENSG00000152822	4.229155388313426	[68,137]	[502,354]	9	dCas9-VP64	positive selection	2419559
146029004	146029027	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTGCCCCCTCTGTCCTCACGG	GRM1	ENSG00000152822	1.3018761397334924	[569,117]	[341,15]	5	dCas9-VP64	positive selection	2419560
146027641	146027664	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAATAGTGCTGAAGAAAGAGGG	GRM1	ENSG00000152822	4.888445979214678	[359,89]	[1782,1102]	9	dCas9-VP64	positive selection	2419561
146027689	146027712	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTCTAATCCAGACGGTGCAAGG	GRM1	ENSG00000152822	7.85983988686854	[156,89]	[61,13071]	9	dCas9-VP64	positive selection	2419562
146062172	146062195	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GATGAGTTCATGTCCTTTGCGGG	GRM1	ENSG00000152822	0.694229254912727	[149,140]	[23,80]	3	dCas9-VP64	positive selection	2427680
146029047	146029070	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	AACAGCTTGGAGCGCAGCTGTGG	GRM1	ENSG00000152822	0.25783198137948315	[100,302]	[61,92]	2	dCas9-VP64	positive selection	2514813
146029070	146029093	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACATCCTGATATCGGCTGCAGG	GRM1	ENSG00000152822	0.0077631970773514025	[125,312]	[52,87]	0	dCas9-VP64	positive selection	2514814
146029004	146029027	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTGCCCCCTCTGTCCTCACGG	GRM1	ENSG00000152822	0.15745819395141258	[210,221]	[89,67]	1	dCas9-VP64	positive selection	2514815
146027641	146027664	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAATAGTGCTGAAGAAAGAGGG	GRM1	ENSG00000152822	2.614459746978397	[841,178]	[764,1286]	9	dCas9-VP64	positive selection	2514816
146027689	146027712	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTCTAATCCAGACGGTGCAAGG	GRM1	ENSG00000152822	4.415285877320739	[126,98]	[53,1486]	9	dCas9-VP64	positive selection	2514817
146062172	146062195	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GATGAGTTCATGTCCTTTGCGGG	GRM1	ENSG00000152822	0.8547963947462619	[154,70]	[111,25]	5	dCas9-VP64	positive selection	2522935
146029855	146029878	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	0.21891209406726725	[2,3]	[4,1]	4	hSpCas9	positive selection	2992101
146029770	146029793	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.6586135607754235	[4,4]	[1,2]	-7	hSpCas9	positive selection	2992102
146030193	146030216	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	0.38548216901513	[3,4]	[4,4]	7	hSpCas9	positive selection	2992103
146029731	146029754	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	0.1597473865423691	[3,3]	[1,4]	3	hSpCas9	positive selection	2992104
146029855	146029878	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	0.11453815615888437	[2,2]	[1,2]	2	hSpCas9	positive selection	3059959
146029770	146029793	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.41883604644251216	[4,4]	[4,3]	7	hSpCas9	positive selection	3059960
146030193	146030216	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	0.5512842405484749	[3,3]	[4,3]	8	hSpCas9	positive selection	3059961
146029731	146029754	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	-0.2702823461851086	[3,3]	[0,2]	-4	hSpCas9	positive selection	3059962
146304825	146304848		+	24336571	A375	resistance to PLX after 7 days	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	0.053130718829099366	[10,7]	[10,8]	2	hSpCas9	positive selection	3117886
146159460	146159483		-	24336571	A375	resistance to PLX after 7 days	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.2181989213119929	[15,17]	[13,14]	-6	hSpCas9	positive selection	3117887
146304661	146304684		-	24336571	A375	resistance to PLX after 7 days	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.10292371704336944	[48,46]	[43,44]	-3	hSpCas9	positive selection	3117888
146159465	146159488		+	24336571	A375	resistance to PLX after 7 days	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.05772700628038374	[18,16]	[18,18]	2	hSpCas9	positive selection	3117889
146304825	146304848		+	24336571	A375	resistance to PLX after 14 days	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	0.18871532839900146	[8,5]	[3,3]	2	hSpCas9	positive selection	3175679
146159460	146159483		-	24336571	A375	resistance to PLX after 14 days	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.9719448825483928	[19,18]	[3,3]	-9	hSpCas9	positive selection	3175680
146304661	146304684		-	24336571	A375	resistance to PLX after 14 days	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.646807095665191	[38,49]	[12,12]	-7	hSpCas9	positive selection	3175681
146159465	146159488		+	24336571	A375	resistance to PLX after 14 days	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.031302284548711534	[27,16]	[9,10]	0	hSpCas9	positive selection	3175682
146304825	146304848		+	24336571	A375	viability after 7 days	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	-1.362232495731167	[26]	[10,7]	-9	hSpCas9	negative selection	3233472
146159460	146159483		-	24336571	A375	viability after 7 days	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	1.0732733881550252	[7]	[15,17]	9	hSpCas9	negative selection	3233473
146304661	146304684		-	24336571	A375	viability after 7 days	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.10075252031548732	[53]	[48,46]	-1	hSpCas9	negative selection	3233474
146159465	146159488		+	24336571	A375	viability after 7 days	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	1.8902913099830148	[4]	[18,16]	9	hSpCas9	negative selection	3233475
146304825	146304848		+	24336571	A375	viability after 14 days	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	-1.6688471496579886	[26]	[8,5]	-9	hSpCas9	negative selection	3291265
146159460	146159483		-	24336571	A375	viability after 14 days	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	1.2564694680844268	[7]	[19,18]	9	hSpCas9	negative selection	3291266
146304661	146304684		-	24336571	A375	viability after 14 days	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.18996965603035343	[53]	[38,49]	-2	hSpCas9	negative selection	3291267
146159465	146159488		+	24336571	A375	viability after 14 days	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	2.197864167192116	[4]	[27,16]	9	hSpCas9	negative selection	3291268
146159465	146159488	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.34361546193684334	[130,109]	[0,0]	1	hSpCas9	positive selection	3352556
146304661	146304684	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-1.109567367180078	[349,309]	[0,0]	-7	hSpCas9	positive selection	3352557
146159460	146159483	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.32280662635116275	[94,149]	[0,0]	1	hSpCas9	positive selection	3352558
146352394	146352417	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3371761
146352381	146352404	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-1.6495643841626835	[479,479]	[0,0]	-9	hSpCas9	positive selection	3371762
146304647	146304670	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.2264895658184215	[178,178]	[0,0]	-1	hSpCas9	positive selection	3371763
146029855	146029878	6	-	26780180	HT29	viability (Avana library 4 designs)	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	0.40765057779796	[]	[]	1	hSpCas9	negative selection	3429303
146029769	146029792	6	+	26780180	HT29	viability (Avana library 4 designs)	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.238998605347427	[]	[]	-4	hSpCas9	negative selection	3429304
146030192	146030215	6	+	26780180	HT29	viability (Avana library 4 designs)	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	-0.560197606363441	[]	[]	-7	hSpCas9	negative selection	3429305
146029730	146029753	6	+	26780180	HT29	viability (Avana library 4 designs)	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	1.914360236561	[]	[]	7	hSpCas9	negative selection	3429306
146029730	146029753	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	3.45044196703614	[]	[]	5	hSpCas9	negative selection	3513911
146030192	146030215	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	0.562254212328281	[]	[]	0	hSpCas9	negative selection	3513912
146029855	146029878	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	5.12288202840645	[]	[]	8	hSpCas9	negative selection	3513913
146029769	146029792	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	2.69145162280075	[]	[]	4	hSpCas9	negative selection	3513914
146030105	146030128	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTACAAATACTTCCTGAGGG	GRM1	ENSG00000152822	-9.40348899583523	[]	[]	-7	hSpCas9	negative selection	3513915
146304647	146304670	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	4.95592755639947	[]	[]	8	hSpCas9	negative selection	3513916
146029730	146029753	6	+	26780180	A375	viability (Avana lentiGuide)	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	-2.08953017020928	[]	[]	-4	hSpCas9	negative selection	3622570
146030192	146030215	6	+	26780180	A375	viability (Avana lentiGuide)	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	-2.92722258264278	[]	[]	-5	hSpCas9	negative selection	3622571
146029855	146029878	6	-	26780180	A375	viability (Avana lentiGuide)	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	-3.14758586140683	[]	[]	-5	hSpCas9	negative selection	3622572
146029769	146029792	6	+	26780180	A375	viability (Avana lentiGuide)	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.937146912272105	[]	[]	-1	hSpCas9	negative selection	3622573
146030105	146030128	6	+	26780180	A375	viability (Avana lentiGuide)	TTTGTACAAATACTTCCTGAGGG	GRM1	ENSG00000152822	-2.50665075122915	[]	[]	-4	hSpCas9	negative selection	3622574
146304647	146304670	6	+	26780180	A375	viability (Avana lentiGuide)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-6.07116452610942	[]	[]	-8	hSpCas9	negative selection	3622575
146029730	146029753	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	-0.006287532110424552	[5]	[4,4]	0	hSpCas9	positive selection	3731229
146030192	146030215	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	0.06576510827606537	[5]	[5,4]	1	hSpCas9	positive selection	3731230
146029855	146029878	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	0.2395476678916472	[5]	[6,5]	6	hSpCas9	positive selection	3731231
146029769	146029792	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.026540768346675875	[5]	[5,6]	0	hSpCas9	positive selection	3731232
146030105	146030128	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTACAAATACTTCCTGAGGG	GRM1	ENSG00000152822	-0.6353801476738531	[7]	[4,4]	-7	hSpCas9	positive selection	3731233
146304647	146304670	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	0.25208518266007707	[4]	[6,5]	7	hSpCas9	positive selection	3731234
146029730	146029753	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCAGTATGGCATCCAGAGGG	GRM1	ENSG00000152822	-0.0060381451229359895	[4]	[4,3]	0	hSpCas9	positive selection	3839836
146030192	146030215	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATGTCTCTGCAGTCCACACGG	GRM1	ENSG00000152822	-0.0036419821867862186	[5]	[5,3]	0	hSpCas9	positive selection	3839837
146029855	146029878	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGCTCTGTTCCAGAGCCACGG	GRM1	ENSG00000152822	0.08861878168629367	[5]	[4,4]	2	hSpCas9	positive selection	3839838
146029769	146029792	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.2901405461913953	[6]	[7,5]	7	hSpCas9	positive selection	3839839
146030105	146030128	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTACAAATACTTCCTGAGGG	GRM1	ENSG00000152822	0.24578741554226521	[6]	[6,5]	6	hSpCas9	positive selection	3839840
146304647	146304670	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	0.297431107102773	[4]	[4,5]	8	hSpCas9	positive selection	3839841
146352394	146352417	6	-	26780180	A375	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.94677017083459	[]	[]	4	hSpCas9	negative selection	3945990
146159460	146159483	6	-	26780180	A375	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.586806327890582	[]	[]	1	hSpCas9	negative selection	3945991
146304661	146304684	6	-	26780180	A375	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.419189636944425	[]	[]	1	hSpCas9	negative selection	3945992
146352381	146352404	6	+	26780180	A375	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	1.10472742403346	[]	[]	5	hSpCas9	negative selection	3945993
146159465	146159488	6	+	26780180	A375	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.927127637006011	[]	[]	4	hSpCas9	negative selection	3945994
146304647	146304670	6	+	26780180	A375	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	1.59031422560428	[]	[]	8	hSpCas9	negative selection	3945995
146352394	146352417	6	-	26780180	HT29	viability (GeCKOv2 library)	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	1.15491014414663	[]	[]	5	hSpCas9	negative selection	4053956
146159460	146159483	6	-	26780180	HT29	viability (GeCKOv2 library)	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.759658371777415	[]	[]	3	hSpCas9	negative selection	4053957
146304661	146304684	6	-	26780180	HT29	viability (GeCKOv2 library)	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.0519182077885341	[]	[]	-1	hSpCas9	negative selection	4053958
146352381	146352404	6	+	26780180	HT29	viability (GeCKOv2 library)	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.684683857103333	[]	[]	2	hSpCas9	negative selection	4053959
146159465	146159488	6	+	26780180	HT29	viability (GeCKOv2 library)	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.684725310049879	[]	[]	2	hSpCas9	negative selection	4053960
146304647	146304670	6	+	26780180	HT29	viability (GeCKOv2 library)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	1.66287006199714	[]	[]	8	hSpCas9	negative selection	4053961
146304825	146304848	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	-0.13417972734741712	[3]	[1,1]	-3	hSpCas9	positive selection	4141248
146159460	146159483	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.23040332163479937	[4]	[2,1]	-5	hSpCas9	positive selection	4141249
146304661	146304684	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.1772012220259906	[5]	[4,3]	4	hSpCas9	positive selection	4141250
146159465	146159488	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.012060794486566606	[4]	[1,3]	0	hSpCas9	positive selection	4141251
146304825	146304848	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACTTTAAACGAATCTGCACAGG	GRM1	ENSG00000152822	0.34970003929700655	[5]	[3,4,5,0]	2	hSpCas9	positive selection	4205270
146159460	146159483	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.6643435043950776	[4]	[0,2,1,0]	-8	hSpCas9	positive selection	4205271
146304661	146304684	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	1.2317070848534668	[5]	[6,4,5,5]	8	hSpCas9	positive selection	4205272
146159465	146159488	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	1.0055763286987642	[3]	[2,3,1,3]	7	hSpCas9	positive selection	4205273
146159465	146159488	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	-0.14385476709919898	[3]	[3,1]	-3	hSpCas9	positive selection	4274025
146304661	146304684	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.5148024088560381	[4]	[4,4]	9	hSpCas9	positive selection	4274026
146159460	146159483	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.10912475446644493	[3]	[3,2]	2	hSpCas9	positive selection	4274027
146352394	146352417	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	-0.1776241994459128	[2]	[3,0]	-4	hSpCas9	positive selection	4338284
146352381	146352404	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.14515809199702778	[3]	[3,2]	3	hSpCas9	positive selection	4338285
146304647	146304670	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.037279730966857286	[3]	[3,1]	0	hSpCas9	positive selection	4338286
146029611	146029633	6	+	27760321	OCIAML3	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	-0.13563698250589962	[1127,1020]	[670,885]	-1	hSpCas9	negative selection	4405467
146029770	146029792	6	+	27760321	OCIAML3	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.3852240189365004	[140,108]	[105,32]	-4	hSpCas9	negative selection	4405468
146029980	146030002	6	-	27760321	OCIAML3	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.03050027232424929	[644,559]	[440,530]	0	hSpCas9	negative selection	4405469
146159562	146159584	6	-	27760321	OCIAML3	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.5319072041458386	[1021,789]	[954,1097]	6	hSpCas9	negative selection	4405470
146304661	146304683	6	-	27760321	OCIAML3	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.4612798064200027	[587,559]	[630,602]	5	hSpCas9	negative selection	4405471
146029611	146029633	6	+	27760321	OCIAML2	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.12515122558144331	[1127,1020]	[828,1102]	1	hSpCas9	negative selection	4488930
146029770	146029792	6	+	27760321	OCIAML2	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.1901770231743607	[140,108]	[98,134]	2	hSpCas9	negative selection	4488931
146029980	146030002	6	-	27760321	OCIAML2	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	-0.30033082616277873	[644,559]	[380,412]	-4	hSpCas9	negative selection	4488932
146159562	146159584	6	-	27760321	OCIAML2	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.31629758234752026	[1021,789]	[782,1067]	4	hSpCas9	negative selection	4488933
146304661	146304683	6	-	27760321	OCIAML2	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.33600002629654463	[587,559]	[563,616]	4	hSpCas9	negative selection	4488934
146029611	146029633	6	+	27760321	MV411	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.2551040774442186	[1127,1020]	[1004,605]	1	hSpCas9	negative selection	4572393
146029770	146029792	6	+	27760321	MV411	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	1.0968211914578585	[140,108]	[117,260]	7	hSpCas9	negative selection	4572394
146029980	146030002	6	-	27760321	MV411	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.8269579004846109	[644,559]	[623,822]	6	hSpCas9	negative selection	4572395
146159562	146159584	6	-	27760321	MV411	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.48596237265528863	[1021,789]	[443,1412]	3	hSpCas9	negative selection	4572396
146304661	146304683	6	-	27760321	MV411	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.20286268484606634	[587,559]	[593,199]	1	hSpCas9	negative selection	4572397
146029611	146029633	6	+	27760321	HL60	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.19575860863001293	[1127,1020]	[887,1127]	2	hSpCas9	negative selection	4655856
146029770	146029792	6	+	27760321	HL60	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.004887535781498142	[140,108]	[101,99]	0	hSpCas9	negative selection	4655857
146029980	146030002	6	-	27760321	HL60	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	-0.26182373685356103	[644,559]	[407,410]	-3	hSpCas9	negative selection	4655858
146159562	146159584	6	-	27760321	HL60	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	-0.11054270429275692	[1021,789]	[648,713]	-1	hSpCas9	negative selection	4655859
146304661	146304683	6	-	27760321	HL60	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.12571542378212364	[587,559]	[423,436]	-1	hSpCas9	negative selection	4655860
146029611	146029633	6	+	27760321	HT1080	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.8198632216857187	[1020,796]	[738,529]	4	hSpCas9	negative selection	4739319
146029770	146029792	6	+	27760321	HT1080	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	1.47052538115071	[108,84]	[34,185]	7	hSpCas9	negative selection	4739320
146029980	146030002	6	-	27760321	HT1080	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	1.036289277781572	[559,436]	[444,365]	5	hSpCas9	negative selection	4739321
146159562	146159584	6	-	27760321	HT1080	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.8032130353318876	[789,616]	[542,429]	4	hSpCas9	negative selection	4739322
146304661	146304683	6	-	27760321	HT1080	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	1.01839375082369	[559,436]	[154,672]	5	hSpCas9	negative selection	4739323
146029611	146029633	6	+	27760321	HT29	viability after 7 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	-0.1853053468593331	[1020,796]	[1483,790,876]	-3	hSpCas9	negative selection	4822782
146029770	146029792	6	+	27760321	HT29	viability after 7 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.12203449529709376	[108,84]	[116,81,143]	-2	hSpCas9	negative selection	4822783
146029980	146030002	6	-	27760321	HT29	viability after 7 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.6465057560387477	[559,436]	[1096,833,1087]	8	hSpCas9	negative selection	4822784
146159562	146159584	6	-	27760321	HT29	viability after 7 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.4897122244964176	[789,616]	[1131,1582,1079]	7	hSpCas9	negative selection	4822785
146304661	146304683	6	-	27760321	HT29	viability after 7 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.25931957151160456	[559,436]	[619,534,464]	-4	hSpCas9	negative selection	4822786
146029611	146029633	6	+	27760321	HT29	viability after 25 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.32427506728801947	[1020,796]	[1254,1173,1493]	3	hSpCas9	negative selection	4906245
146029770	146029792	6	+	27760321	HT29	viability after 25 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.26610154393047036	[108,84]	[46,113,256]	2	hSpCas9	negative selection	4906246
146029980	146030002	6	-	27760321	HT29	viability after 25 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.6609675453592572	[559,436]	[658,950,1129]	7	hSpCas9	negative selection	4906247
146159562	146159584	6	-	27760321	HT29	viability after 25 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.7957331455372998	[789,616]	[1421,1377,1381]	8	hSpCas9	negative selection	4906248
146304661	146304683	6	-	27760321	HT29	viability after 25 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.13512072700471	[559,436]	[390,442,753]	-1	hSpCas9	negative selection	4906249
146029611	146029633	6	+	27760321	HT29	viability after 22 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.22636892064712466	[1020,796]	[1407,1075,1198]	2	hSpCas9	negative selection	4989708
146029770	146029792	6	+	27760321	HT29	viability after 22 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.32834273969745587	[108,84]	[59,88,119]	-3	hSpCas9	negative selection	4989709
146029980	146030002	6	-	27760321	HT29	viability after 22 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.7116222727791741	[559,436]	[1062,924,838]	7	hSpCas9	negative selection	4989710
146159562	146159584	6	-	27760321	HT29	viability after 22 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.8266555138415512	[789,616]	[1456,1423,1445]	8	hSpCas9	negative selection	4989711
146304661	146304683	6	-	27760321	HT29	viability after 22 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.051284266346355745	[559,436]	[551,619,495]	0	hSpCas9	negative selection	4989712
146029611	146029633	6	+	27760321	HT29	viability after 19 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.33705385328956194	[1020,796]	[1810,1352,844]	3	hSpCas9	negative selection	5073171
146029770	146029792	6	+	27760321	HT29	viability after 19 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.2053143215016111	[108,84]	[112,139,128]	2	hSpCas9	negative selection	5073172
146029980	146030002	6	-	27760321	HT29	viability after 19 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.11788688457001734	[559,436]	[922,414,551]	1	hSpCas9	negative selection	5073173
146159562	146159584	6	-	27760321	HT29	viability after 19 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.875499099150312	[789,616]	[1407,1525,1485]	8	hSpCas9	negative selection	5073174
146304661	146304683	6	-	27760321	HT29	viability after 19 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.4263389454349558	[559,436]	[403,271,587]	-4	hSpCas9	negative selection	5073175
146029611	146029633	6	+	27760321	HT29	viability after 16 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.19564968898200275	[1020,796]	[1526,1209,789]	2	hSpCas9	negative selection	5156634
146029770	146029792	6	+	27760321	HT29	viability after 16 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	-0.31171388858074156	[108,84]	[167,44,57]	-3	hSpCas9	negative selection	5156635
146029980	146030002	6	-	27760321	HT29	viability after 16 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.08211305264199636	[559,436]	[614,604,552]	0	hSpCas9	negative selection	5156636
146159562	146159584	6	-	27760321	HT29	viability after 16 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.8438557622427907	[789,616]	[1545,1128,1582]	8	hSpCas9	negative selection	5156637
146304661	146304683	6	-	27760321	HT29	viability after 16 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.3862102227910859	[559,436]	[335,447,486]	-4	hSpCas9	negative selection	5156638
146029611	146029633	6	+	27760321	HT29	viability after 13 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.3424370668908172	[1020,796]	[1332,1307,1367]	4	hSpCas9	negative selection	5240097
146029770	146029792	6	+	27760321	HT29	viability after 13 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.4846850147558981	[108,84]	[155,67,242]	6	hSpCas9	negative selection	5240098
146029980	146030002	6	-	27760321	HT29	viability after 13 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.3946401748448644	[559,436]	[781,830,672]	5	hSpCas9	negative selection	5240099
146159562	146159584	6	-	27760321	HT29	viability after 13 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.7655827221528877	[789,616]	[1375,1579,1216]	8	hSpCas9	negative selection	5240100
146304661	146304683	6	-	27760321	HT29	viability after 13 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.2855554911970306	[559,436]	[555,373,491]	-4	hSpCas9	negative selection	5240101
146029611	146029633	6	+	27760321	HT29	viability after 10 days	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.28138306128047197	[1020,796]	[1814,1306,1021]	4	hSpCas9	negative selection	5323560
146029770	146029792	6	+	27760321	HT29	viability after 10 days	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	0.21934370480223753	[108,84]	[82,147,190]	3	hSpCas9	negative selection	5323561
146029980	146030002	6	-	27760321	HT29	viability after 10 days	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	0.7171903328291567	[559,436]	[842,833,1378]	8	hSpCas9	negative selection	5323562
146159562	146159584	6	-	27760321	HT29	viability after 10 days	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.7662197722120709	[789,616]	[1427,1328,1714]	9	hSpCas9	negative selection	5323563
146304661	146304683	6	-	27760321	HT29	viability after 10 days	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.2311772100682894	[559,436]	[479,699,417]	-3	hSpCas9	negative selection	5323564
146029611	146029633	6	+	27760321	MOLM13	viability	GCGTCGTCTCAGCGCTCGGTGG	GRM1	ENSG00000152822	0.03991918383933468	[1127,1020]	[975,321]	0	hSpCas9	negative selection	5407023
146029770	146029792	6	+	27760321	MOLM13	viability	ACGTTGGATAAGATCAACGCGG	GRM1	ENSG00000152822	1.4471861350395516	[140,108]	[413,0]	8	hSpCas9	negative selection	5407024
146029980	146030002	6	-	27760321	MOLM13	viability	GACCGATCACTCCCGCAATGGG	GRM1	ENSG00000152822	-0.16675953597644844	[644,559]	[159,422]	-1	hSpCas9	negative selection	5407025
146159562	146159584	6	-	27760321	MOLM13	viability	GAACTCGCCCACGACGCCAAGG	GRM1	ENSG00000152822	0.829621818333822	[1021,789]	[768,1014]	6	hSpCas9	negative selection	5407026
146304661	146304683	6	-	27760321	MOLM13	viability	TTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	-0.9457738296121612	[587,559]	[230,114]	-5	hSpCas9	negative selection	5407027
146028131	146028154	6	+	27661255	K562	viability	GCCTCTGTCCCCAAGCGGGTGGG	GRM1	ENSG00000152822	-0.10872699044696965	[208,258]	[176,168]	-4	dCas9-KRAB	negative selection	5483456
146028007	146028030	6	-	27661255	K562	viability	GCGGGCGAGGAGAGCACAGGAGG	GRM1	ENSG00000152822	0.1145033397952591	[758,826]	[735,640]	4	dCas9-KRAB	negative selection	5483457
146028097	146028120	6	-	27661255	K562	viability	GCCGCCTGCGGGGCTGAAGTTGG	GRM1	ENSG00000152822	-0.04516751372590344	[532,603]	[504,382]	-2	dCas9-KRAB	negative selection	5483458
146159465	146159488	6	+	27260156	BXPC3	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	-0.20123813037041174	[545]	[482,432,439,649]	-4	hSpCas9	negative selection	5546485
146304661	146304684	6	-	27260156	BXPC3	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.1981793769677891	[1079]	[1085,1378,1260,1487]	4	hSpCas9	negative selection	5546486
146159460	146159483	6	-	27260156	BXPC3	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.11479109059286752	[799]	[866,623,710,894]	-3	hSpCas9	negative selection	5546487
146352394	146352417	6	-	27260156	BXPC3	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.3275689375121809	[363]	[388,537,431,563]	7	hSpCas9	negative selection	5610744
146352381	146352404	6	+	27260156	BXPC3	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.036138760507988144	[881]	[897,829,958,1122]	0	hSpCas9	negative selection	5610745
146304647	146304670	6	+	27260156	BXPC3	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.3741123266192168	[539]	[468,409,356,508]	-7	hSpCas9	negative selection	5610746
146159465	146159488	6	+	27260156	A673	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.13310361209245863	[545]	[797,642,702,742]	3	hSpCas9	negative selection	5667736
146304661	146304684	6	-	27260156	A673	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.2503114306612837	[1079]	[1726,1542,1356,1563]	6	hSpCas9	negative selection	5667737
146159460	146159483	6	-	27260156	A673	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.22953288453690723	[799]	[1243,1057,1066,1150]	5	hSpCas9	negative selection	5667738
146352394	146352417	6	-	27260156	A673	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.08681574514572954	[363]	[495,463,401,499]	2	hSpCas9	negative selection	5731995
146352381	146352404	6	+	27260156	A673	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.07638344613821302	[881]	[1251,961,1190,1075]	1	hSpCas9	negative selection	5731996
146304647	146304670	6	+	27260156	A673	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.27172559721765754	[539]	[558,515,542,531]	-6	hSpCas9	negative selection	5731997
146159465	146159488	6	+	27260156	A375	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.48540473604485634	[545]	[900,1245,836,660]	7	hSpCas9	negative selection	5788987
146304661	146304684	6	-	27260156	A375	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3588148603869963	[1079]	[1904,1818,1408,1388]	5	hSpCas9	negative selection	5788988
146159460	146159483	6	-	27260156	A375	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.07082959597387894	[799]	[988,1090,920,940]	1	hSpCas9	negative selection	5788989
146352394	146352417	6	-	27260156	A375	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.2514700153048813	[363]	[519,518,586,409]	3	hSpCas9	negative selection	5853246
146352381	146352404	6	+	27260156	A375	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.22584778557935958	[881]	[1129,1484,1155,1094]	3	hSpCas9	negative selection	5853247
146304647	146304670	6	+	27260156	A375	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.38974763915262967	[539]	[533,446,416,516]	-5	hSpCas9	negative selection	5853248
146159465	146159488	6	+	27260156	COLO741	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.22540848444789685	[545]	[868,828,755]	5	hSpCas9	negative selection	5910238
146304661	146304684	6	-	27260156	COLO741	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.16894091812788847	[1079]	[1599,1466,1584]	3	hSpCas9	negative selection	5910239
146159460	146159483	6	-	27260156	COLO741	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.003814246274532196	[799]	[1301,834,947]	0	hSpCas9	negative selection	5910240
146352394	146352417	6	-	27260156	COLO741	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.12022286315761518	[363]	[551,597,378]	2	hSpCas9	negative selection	5974497
146352381	146352404	6	+	27260156	COLO741	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.12706359991136118	[881]	[961,1125,1001]	-3	hSpCas9	negative selection	5974498
146304647	146304670	6	+	27260156	COLO741	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.21055381348506572	[539]	[746,582,478]	-4	hSpCas9	negative selection	5974499
146159465	146159488	6	+	27260156	CAL120	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.01647077904765709	[545]	[558,564,913]	0	hSpCas9	negative selection	6031489
146304661	146304684	6	-	27260156	CAL120	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.5218578215936338	[1079]	[2391,1722,1745]	7	hSpCas9	negative selection	6031490
146159460	146159483	6	-	27260156	CAL120	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.057938089543653315	[799]	[1074,998,814]	-1	hSpCas9	negative selection	6031491
146352394	146352417	6	-	27260156	CAL120	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.4315711366916124	[363]	[755,638,461]	6	hSpCas9	negative selection	6095748
146352381	146352404	6	+	27260156	CAL120	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.026635474647017654	[881]	[1352,986,935]	0	hSpCas9	negative selection	6095749
146304647	146304670	6	+	27260156	CAL120	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.15318816054824672	[539]	[753,526,554]	-2	hSpCas9	negative selection	6095750
146159465	146159488	6	+	27260156	CADOES1	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.10303060845732115	[545]	[463,654,569,490]	1	hSpCas9	negative selection	6152740
146304661	146304684	6	-	27260156	CADOES1	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.17248873658928887	[1079]	[1094,1059,1292,1077]	3	hSpCas9	negative selection	6152741
146159460	146159483	6	-	27260156	CADOES1	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.043922105033137315	[799]	[743,566,790,786]	0	hSpCas9	negative selection	6152742
146352394	146352417	6	-	27260156	CADOES1	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.2474889663668165	[363]	[317,429,351,511]	4	hSpCas9	negative selection	6216999
146352381	146352404	6	+	27260156	CADOES1	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.26780287223229793	[881]	[557,630,740,799]	-4	hSpCas9	negative selection	6217000
146304647	146304670	6	+	27260156	CADOES1	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.579792246782435	[539]	[349,299,229,468]	-8	hSpCas9	negative selection	6217001
146159465	146159488	6	+	27260156	EWS502	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.08658081969417003	[545]	[565,598,542,761]	1	hSpCas9	negative selection	6273991
146304661	146304684	6	-	27260156	EWS502	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.0991537696662046	[1079]	[1267,1202,1158,1263]	1	hSpCas9	negative selection	6273992
146159460	146159483	6	-	27260156	EWS502	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.11100314187669214	[799]	[729,1011,888,1053]	2	hSpCas9	negative selection	6273993
146352394	146352417	6	-	27260156	EWS502	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.3760349851071008	[363]	[407,633,504,454]	6	hSpCas9	negative selection	6338250
146352381	146352404	6	+	27260156	EWS502	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.24234233258211157	[881]	[987,1216,1079,1142]	4	hSpCas9	negative selection	6338251
146304647	146304670	6	+	27260156	EWS502	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.23698309774178325	[539]	[457,412,479,602]	-4	hSpCas9	negative selection	6338252
146159465	146159488	6	+	27260156	EW8	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.18702749657477263	[545]	[570,458,435,565]	3	hSpCas9	negative selection	6395242
146304661	146304684	6	-	27260156	EW8	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.20913616514153643	[1079]	[1150,1137,824,977]	4	hSpCas9	negative selection	6395243
146159460	146159483	6	-	27260156	EW8	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.2739280245710729	[799]	[1116,669,651,752]	5	hSpCas9	negative selection	6395244
146352394	146352417	6	-	27260156	EW8	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.010753318399675749	[363]	[221,279,334,335]	0	hSpCas9	negative selection	6459501
146352381	146352404	6	+	27260156	EW8	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.28805960704915434	[881]	[635,578,540,596]	-5	hSpCas9	negative selection	6459502
146304647	146304670	6	+	27260156	EW8	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.11453997533710768	[539]	[508,350,362,410]	-2	hSpCas9	negative selection	6459503
146159465	146159488	6	+	27260156	CORL105	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.48881837039230813	[545]	[1154,771,962,719]	8	hSpCas9	negative selection	6516493
146304661	146304684	6	-	27260156	CORL105	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3847788236339049	[1079]	[1780,1470,1785,1593]	7	hSpCas9	negative selection	6516494
146159460	146159483	6	-	27260156	CORL105	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.17859313568536095	[799]	[1030,873,1145,1203]	3	hSpCas9	negative selection	6516495
146352394	146352417	6	-	27260156	CORL105	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.42856399011943647	[363]	[553,475,881,431]	7	hSpCas9	negative selection	6580752
146352381	146352404	6	+	27260156	CORL105	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.2153628461826146	[881]	[1079,1424,1244,1043]	4	hSpCas9	negative selection	6580753
146304647	146304670	6	+	27260156	CORL105	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	0.00581855647757662	[539]	[617,581,791,571]	0	hSpCas9	negative selection	6580754
146159465	146159488	6	+	27260156	HS294T	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.23003541301766722	[545]	[151,246,296,313]	3	hSpCas9	negative selection	6637744
146304661	146304684	6	-	27260156	HS294T	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.09942284307575489	[1079]	[491,381,403,519]	1	hSpCas9	negative selection	6637745
146159460	146159483	6	-	27260156	HS294T	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.02164849816725911	[799]	[220,218,303,520]	0	hSpCas9	negative selection	6637746
146352394	146352417	6	-	27260156	HS294T	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.15130108294052438	[363]	[142,163,150,169]	2	hSpCas9	negative selection	6702003
146352381	146352404	6	+	27260156	HS294T	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.11888575256808653	[881]	[244,351,394,526]	1	hSpCas9	negative selection	6702004
146304647	146304670	6	+	27260156	HS294T	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.8403952641260742	[539]	[146,81,99,138]	-8	hSpCas9	negative selection	6702005
146159465	146159488	6	+	27260156	HCC44	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.11538982376075102	[545]	[734,707,782,470]	1	hSpCas9	negative selection	6758995
146304661	146304684	6	-	27260156	HCC44	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.33039379156702653	[1079]	[1730,1293,1830,1382]	5	hSpCas9	negative selection	6758996
146159460	146159483	6	-	27260156	HCC44	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.23817858725092456	[799]	[1079,1067,1223,920]	4	hSpCas9	negative selection	6758997
146352394	146352417	6	-	27260156	HCC44	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.5734621860824902	[363]	[978,401,591,534]	8	hSpCas9	negative selection	6823254
146352381	146352404	6	+	27260156	HCC44	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.2949858633284531	[881]	[1014,839,1489,1608]	5	hSpCas9	negative selection	6823255
146304647	146304670	6	+	27260156	HCC44	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.32180061624012335	[539]	[745,311,586,374]	-5	hSpCas9	negative selection	6823256
146159465	146159488	6	+	27260156	G402	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.3114309938903095	[545]	[659,918,1216,504]	4	hSpCas9	negative selection	6880246
146304661	146304684	6	-	27260156	G402	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.27561078195596367	[1079]	[1907,2188,1071,1299]	3	hSpCas9	negative selection	6880247
146159460	146159483	6	-	27260156	G402	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.08199183635919194	[799]	[1045,1191,1185,730]	1	hSpCas9	negative selection	6880248
146352394	146352417	6	-	27260156	G402	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	1.1513269037284473	[363]	[1231,912,1042,794]	9	hSpCas9	negative selection	6944505
146352381	146352404	6	+	27260156	G402	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.3523687703407782	[881]	[1571,1074,1507,1347]	4	hSpCas9	negative selection	6944506
146304647	146304670	6	+	27260156	G402	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.5661435257070829	[539]	[378,381,405,590]	-6	hSpCas9	negative selection	6944507
146159465	146159488	6	+	27260156	L33	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.15266478829220415	[545]	[564,255,439,539]	3	hSpCas9	negative selection	7001497
146304661	146304684	6	-	27260156	L33	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3937579614416724	[1079]	[1345,605,935,1363]	7	hSpCas9	negative selection	7001498
146159460	146159483	6	-	27260156	L33	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.15224981632525836	[799]	[921,339,563,905]	3	hSpCas9	negative selection	7001499
146352394	146352417	6	-	27260156	L33	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	-0.27884696354814376	[363]	[214,158,180,310]	-6	hSpCas9	negative selection	7065756
146352381	146352404	6	+	27260156	L33	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.05069738081509201	[881]	[758,366,578,832]	-1	hSpCas9	negative selection	7065757
146304647	146304670	6	+	27260156	L33	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.325496606788395	[539]	[333,200,270,469]	-6	hSpCas9	negative selection	7065758
146159465	146159488	6	+	27260156	K562	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.26037328077195826	[545]	[357,665,235,995]	3	hSpCas9	negative selection	7122748
146304661	146304684	6	-	27260156	K562	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.13395997420322647	[1079]	[1425,708,1104,982]	1	hSpCas9	negative selection	7122749
146159460	146159483	6	-	27260156	K562	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.4286271787055671	[799]	[1281,964,950,679]	5	hSpCas9	negative selection	7122750
146352394	146352417	6	-	27260156	K562	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.7190445648195312	[363]	[530,407,806,388]	8	hSpCas9	negative selection	7187007
146352381	146352404	6	+	27260156	K562	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.3421776959382016	[881]	[1015,1407,756,826]	4	hSpCas9	negative selection	7187008
146304647	146304670	6	+	27260156	K562	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.9324588851448222	[539]	[130,204,214,419]	-8	hSpCas9	negative selection	7187009
146159465	146159488	6	+	27260156	HT29	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.1876719348206462	[545]	[623,1145,770,528]	3	hSpCas9	negative selection	7243999
146304661	146304684	6	-	27260156	HT29	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.34657767714725196	[1079]	[2174,1579,1420,1536]	6	hSpCas9	negative selection	7244000
146159460	146159483	6	-	27260156	HT29	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.26602572984567474	[799]	[1280,1318,1113,997]	5	hSpCas9	negative selection	7244001
146352394	146352417	6	-	27260156	HT29	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.14241915662036406	[363]	[331,547,519,536]	2	hSpCas9	negative selection	7308258
146352381	146352404	6	+	27260156	HT29	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.23774362201388322	[881]	[1139,1498,1465,987]	4	hSpCas9	negative selection	7308259
146304647	146304670	6	+	27260156	HT29	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.31097371952952346	[539]	[633,500,450,531]	-6	hSpCas9	negative selection	7308260
146159465	146159488	6	+	27260156	MHHES1	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.10127474141865883	[545]	[853,878,549,437]	1	hSpCas9	negative selection	7365250
146304661	146304684	6	-	27260156	MHHES1	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.40679806253763773	[1079]	[1893,1747,1826,1111]	7	hSpCas9	negative selection	7365251
146159460	146159483	6	-	27260156	MHHES1	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.04695049425418807	[799]	[1011,646,1019,989]	0	hSpCas9	negative selection	7365252
146352394	146352417	6	-	27260156	MHHES1	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.05199832881210048	[363]	[438,432,352,458]	1	hSpCas9	negative selection	7429509
146352381	146352404	6	+	27260156	MHHES1	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.013939634933387013	[881]	[1266,1073,870,850]	0	hSpCas9	negative selection	7429510
146304647	146304670	6	+	27260156	MHHES1	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.3385095537396755	[539]	[649,454,365,462]	-6	hSpCas9	negative selection	7429511
146159465	146159488	6	+	27260156	MEWO	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.12025751229541298	[545]	[844,489,386]	2	hSpCas9	negative selection	7486501
146304661	146304684	6	-	27260156	MEWO	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.21184759248409035	[1079]	[1332,1158,1049]	4	hSpCas9	negative selection	7486502
146159460	146159483	6	-	27260156	MEWO	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.1457867223862559	[799]	[948,695,862]	3	hSpCas9	negative selection	7486503
146352394	146352417	6	-	27260156	MEWO	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.012984204904601893	[363]	[393,251,394]	0	hSpCas9	negative selection	7550760
146352381	146352404	6	+	27260156	MEWO	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.2914882320030753	[881]	[1361,753,982]	6	hSpCas9	negative selection	7550761
146304647	146304670	6	+	27260156	MEWO	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.3608770157029605	[539]	[445,248,495]	-7	hSpCas9	negative selection	7550762
146159465	146159488	6	+	27260156	LNCAPCLONEFGC	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.32408063504422346	[545]	[601,475,793,639]	5	hSpCas9	negative selection	7607752
146304661	146304684	6	-	27260156	LNCAPCLONEFGC	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3466565784707951	[1079]	[1351,1392,1072,1119]	5	hSpCas9	negative selection	7607753
146159460	146159483	6	-	27260156	LNCAPCLONEFGC	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.15096652886100936	[799]	[708,641,713,553]	-2	hSpCas9	negative selection	7607754
146352394	146352417	6	-	27260156	LNCAPCLONEFGC	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.3704656177065596	[363]	[299,332,618,489]	6	hSpCas9	negative selection	7672011
146352381	146352404	6	+	27260156	LNCAPCLONEFGC	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.2604274122738298	[881]	[695,1182,1188,783]	4	hSpCas9	negative selection	7672012
146304647	146304670	6	+	27260156	LNCAPCLONEFGC	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.24963163432609028	[539]	[336,440,505,374]	-4	hSpCas9	negative selection	7672013
146159465	146159488	6	+	27260156	PANC0327	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.4141372778230725	[545]	[819,582,469,733]	6	hSpCas9	negative selection	7729003
146304661	146304684	6	-	27260156	PANC0327	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.1891008963857368	[1079]	[1286,1205,1021,860]	2	hSpCas9	negative selection	7729004
146159460	146159483	6	-	27260156	PANC0327	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.23403808383875213	[799]	[689,792,1078,774]	3	hSpCas9	negative selection	7729005
146352394	146352417	6	-	27260156	PANC0327	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.4411158857049512	[363]	[602,454,303,404]	6	hSpCas9	negative selection	7793262
146352381	146352404	6	+	27260156	PANC0327	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.1063132225631539	[881]	[818,747,1016,799]	1	hSpCas9	negative selection	7793263
146304647	146304670	6	+	27260156	PANC0327	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.698894269908988	[539]	[397,236,329,232]	-7	hSpCas9	negative selection	7793264
146159465	146159488	6	+	27260156	NCIH2009	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.4177307704189891	[545]	[1448,872,820]	6	hSpCas9	negative selection	7850254
146304661	146304684	6	-	27260156	NCIH2009	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.34471902424547274	[1079]	[2287,1685,1848]	5	hSpCas9	negative selection	7850255
146159460	146159483	6	-	27260156	NCIH2009	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.325715846228732	[799]	[1141,860,720]	-4	hSpCas9	negative selection	7850256
146352394	146352417	6	-	27260156	NCIH2009	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.8170754156034171	[363]	[1200,938,605]	9	hSpCas9	negative selection	7914513
146352381	146352404	6	+	27260156	NCIH2009	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.18776138496891193	[881]	[1137,1025,1091]	-3	hSpCas9	negative selection	7914514
146304647	146304670	6	+	27260156	NCIH2009	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	0.1443614769480763	[539]	[875,916,713]	2	hSpCas9	negative selection	7914515
146159465	146159488	6	+	27260156	NCIH1373	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.03853817604023285	[545]	[432,366,682,275]	0	hSpCas9	negative selection	7971505
146304661	146304684	6	-	27260156	NCIH1373	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3388484682063233	[1079]	[2474,1403,1238,299]	3	hSpCas9	negative selection	7971506
146159460	146159483	6	-	27260156	NCIH1373	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.3279460042855439	[799]	[770,518,664,247]	-3	hSpCas9	negative selection	7971507
146352394	146352417	6	-	27260156	NCIH1373	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.23843893831049148	[363]	[501,662,251,129]	2	hSpCas9	negative selection	8035764
146352381	146352404	6	+	27260156	NCIH1373	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.3084501007536825	[881]	[839,822,815,185]	-3	hSpCas9	negative selection	8035765
146304647	146304670	6	+	27260156	NCIH1373	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.4615676616952318	[539]	[478,304,562,111]	-4	hSpCas9	negative selection	8035766
146159465	146159488	6	+	27260156	PATU8902	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.7230389527845813	[545]	[845,1080,1572,1456]	7	hSpCas9	negative selection	8092756
146304661	146304684	6	-	27260156	PATU8902	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.4464846574420196	[1079]	[2088,1814,1701,2748]	4	hSpCas9	negative selection	8092757
146159460	146159483	6	-	27260156	PATU8902	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.11703507296215165	[799]	[1101,1511,805,699]	-1	hSpCas9	negative selection	8092758
146352394	146352417	6	-	27260156	PATU8902	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.9732663258548535	[363]	[1243,665,927,1168]	9	hSpCas9	negative selection	8157015
146352381	146352404	6	+	27260156	PATU8902	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.6564011886771399	[881]	[954,797,605,796]	-6	hSpCas9	negative selection	8157016
146304647	146304670	6	+	27260156	PATU8902	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.7645538367091667	[539]	[351,539,313,616]	-6	hSpCas9	negative selection	8157017
146159465	146159488	6	+	27260156	PANC1	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.22553687874908274	[545]	[574,868,380,440]	3	hSpCas9	negative selection	8214007
146304661	146304684	6	-	27260156	PANC1	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3380701293412358	[1079]	[1125,1309,1327,970]	5	hSpCas9	negative selection	8214008
146159460	146159483	6	-	27260156	PANC1	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.12270325412739058	[799]	[790,1010,660,594]	2	hSpCas9	negative selection	8214009
146352394	146352417	6	-	27260156	PANC1	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.5047480563855813	[363]	[444,470,377,472]	7	hSpCas9	negative selection	8278266
146352381	146352404	6	+	27260156	PANC1	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.23693342099827908	[881]	[847,1016,1187,583]	4	hSpCas9	negative selection	8278267
146304647	146304670	6	+	27260156	PANC1	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.32213222429152966	[539]	[303,371,340,448]	-5	hSpCas9	negative selection	8278268
146159465	146159488	6	+	27260156	PANC0813	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.022645972432499994	[545]	[713,728,549,618]	0	hSpCas9	negative selection	8335258
146304661	146304684	6	-	27260156	PANC0813	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3783972451322575	[1079]	[1876,1529,1622,1587]	6	hSpCas9	negative selection	8335259
146159460	146159483	6	-	27260156	PANC0813	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.02412742775101251	[799]	[1222,1028,909,579]	0	hSpCas9	negative selection	8335260
146352394	146352417	6	-	27260156	PANC0813	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.5500638300877527	[363]	[418,524,822,712]	8	hSpCas9	negative selection	8399517
146352381	146352404	6	+	27260156	PANC0813	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.016403613327206745	[881]	[1299,1011,900,1001]	0	hSpCas9	negative selection	8399518
146304647	146304670	6	+	27260156	PANC0813	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.04070215202945268	[539]	[590,649,533,683]	0	hSpCas9	negative selection	8399519
146159465	146159488	6	+	27260156	RDES	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.07570352200761882	[545]	[612,579,792,662]	1	hSpCas9	negative selection	8456509
146304661	146304684	6	-	27260156	RDES	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.12844410429048136	[1079]	[1041,1536,1417,1460]	2	hSpCas9	negative selection	8456510
146159460	146159483	6	-	27260156	RDES	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.14213192834349853	[799]	[713,630,915,1144]	-2	hSpCas9	negative selection	8456511
146352394	146352417	6	-	27260156	RDES	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.3453081214516648	[363]	[453,535,516,634]	5	hSpCas9	negative selection	8520768
146352381	146352404	6	+	27260156	RDES	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.17476751035554583	[881]	[831,878,868,1017]	-3	hSpCas9	negative selection	8520769
146304647	146304670	6	+	27260156	RDES	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.70694621220913	[539]	[206,378,334,671]	-8	hSpCas9	negative selection	8520770
146159465	146159488	6	+	27260156	PC3	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.41070995708605795	[545]	[514,553,1439,685]	8	hSpCas9	negative selection	8577760
146304661	146304684	6	-	27260156	PC3	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3914523421042466	[1079]	[823,1373,2195,1702]	7	hSpCas9	negative selection	8577761
146159460	146159483	6	-	27260156	PC3	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.2686335721879758	[799]	[681,919,1316,1086]	6	hSpCas9	negative selection	8577762
146352394	146352417	6	-	27260156	PC3	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.3273166876343301	[363]	[315,332,706,588]	7	hSpCas9	negative selection	8642019
146352381	146352404	6	+	27260156	PC3	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.09473736882322481	[881]	[615,1288,1175,781]	2	hSpCas9	negative selection	8642020
146304647	146304670	6	+	27260156	PC3	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.5109415635771047	[539]	[168,384,698,449]	-8	hSpCas9	negative selection	8642021
146159465	146159488	6	+	27260156	PATU8988T	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	-0.18116181469698991	[545]	[621,405,413,409]	-3	hSpCas9	negative selection	8699011
146304661	146304684	6	-	27260156	PATU8988T	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.10937574005381623	[1079]	[1184,1212,852,1275]	2	hSpCas9	negative selection	8699012
146159460	146159483	6	-	27260156	PATU8988T	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.16724937333600487	[799]	[891,929,817,835]	3	hSpCas9	negative selection	8699013
146352394	146352417	6	-	27260156	PATU8988T	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.5178267373024146	[363]	[566,585,493,363]	8	hSpCas9	negative selection	8763270
146352381	146352404	6	+	27260156	PATU8988T	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.1735858729706582	[881]	[1159,695,634,1365]	3	hSpCas9	negative selection	8763271
146304647	146304670	6	+	27260156	PATU8988T	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	0.029381395957770867	[539]	[852,492,400,367]	0	hSpCas9	negative selection	8763272
146159465	146159488	6	+	27260156	T47D	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.3143857721282787	[545]	[794,682,845,849]	6	hSpCas9	negative selection	8820262
146304661	146304684	6	-	27260156	T47D	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.3550075136495803	[1079]	[1655,1397,1586,1820]	7	hSpCas9	negative selection	8820263
146159460	146159483	6	-	27260156	T47D	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.1693997840071596	[799]	[1064,913,1089,1136]	3	hSpCas9	negative selection	8820264
146352394	146352417	6	-	27260156	T47D	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.12478338990874194	[363]	[450,455,429,514]	2	hSpCas9	negative selection	8884521
146352381	146352404	6	+	27260156	T47D	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.15827129836278353	[881]	[1131,1041,1217,1203]	3	hSpCas9	negative selection	8884522
146304647	146304670	6	+	27260156	T47D	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.1784386421834774	[539]	[628,521,504,571]	-4	hSpCas9	negative selection	8884523
146159465	146159488	6	+	27260156	SU8686	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.22517571169989115	[545]	[508,632,658,760]	4	hSpCas9	negative selection	8941513
146304661	146304684	6	-	27260156	SU8686	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.22503328020919322	[1079]	[1262,1083,1204,1504]	4	hSpCas9	negative selection	8941514
146159460	146159483	6	-	27260156	SU8686	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.015185449024526676	[799]	[777,669,801,921]	0	hSpCas9	negative selection	8941515
146352394	146352417	6	-	27260156	SU8686	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.4737667342129743	[363]	[444,467,521,591]	7	hSpCas9	negative selection	9005772
146352381	146352404	6	+	27260156	SU8686	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.08370731534251397	[881]	[718,772,1039,779]	-1	hSpCas9	negative selection	9005773
146304647	146304670	6	+	27260156	SU8686	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.48296884447585875	[539]	[380,374,415,354]	-6	hSpCas9	negative selection	9005774
146159465	146159488	6	+	27260156	SKES1	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.02523344900462654	[545]	[685,623,456,480]	0	hSpCas9	negative selection	9062764
146304661	146304684	6	-	27260156	SKES1	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.37224294518434875	[1079]	[1787,1649,1124,1121]	7	hSpCas9	negative selection	9062765
146159460	146159483	6	-	27260156	SKES1	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.005196814493613644	[799]	[887,999,589,740]	0	hSpCas9	negative selection	9062766
146352394	146352417	6	-	27260156	SKES1	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.45576638056919405	[363]	[669,413,507,417]	8	hSpCas9	negative selection	9127023
146352381	146352404	6	+	27260156	SKES1	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.007054726809818557	[881]	[1162,736,903,758]	0	hSpCas9	negative selection	9127024
146304647	146304670	6	+	27260156	SKES1	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.26508078225198073	[539]	[389,586,529,305]	-5	hSpCas9	negative selection	9127025
146159465	146159488	6	+	27260156	TOV112D	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.14466919109313425	[545]	[634,923,432,508]	3	hSpCas9	negative selection	9184015
146304661	146304684	6	-	27260156	TOV112D	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.41543498133828405	[1079]	[1346,1850,1307,1356]	7	hSpCas9	negative selection	9184016
146159460	146159483	6	-	27260156	TOV112D	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.026742152498429372	[799]	[730,997,706,756]	0	hSpCas9	negative selection	9184017
146352394	146352417	6	-	27260156	TOV112D	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	-0.1333249510580533	[363]	[278,397,271,389]	-3	hSpCas9	negative selection	9248274
146352381	146352404	6	+	27260156	TOV112D	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.09023488451725503	[881]	[1012,1030,934,812]	1	hSpCas9	negative selection	9248275
146304647	146304670	6	+	27260156	TOV112D	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.1583994683504432	[539]	[330,559,305,738]	-3	hSpCas9	negative selection	9248276
146159465	146159488	6	+	27260156	TC71	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	0.06897960158349348	[545]	[469,557,695,739]	1	hSpCas9	negative selection	9305266
146304661	146304684	6	-	27260156	TC71	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.23589849346485425	[1079]	[1213,1360,1211,1694]	6	hSpCas9	negative selection	9305267
146159460	146159483	6	-	27260156	TC71	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	0.15367853797224573	[799]	[945,989,983,890]	4	hSpCas9	negative selection	9305268
146352394	146352417	6	-	27260156	TC71	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.1466604141692007	[363]	[527,401,392,401]	3	hSpCas9	negative selection	9369525
146352381	146352404	6	+	27260156	TC71	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	0.057214087764076216	[881]	[927,1061,1008,932]	1	hSpCas9	negative selection	9369526
146304647	146304670	6	+	27260156	TC71	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.4926307925185818	[539]	[399,403,441,397]	-8	hSpCas9	negative selection	9369527
146159465	146159488	6	+	27260156	TC32	viability	TCTTGCGCAAACTCCGAGAGAGG	GRM1	ENSG00000152822	-0.054358796984519814	[545]	[434,392,677,519]	-1	hSpCas9	negative selection	9426517
146304661	146304684	6	-	27260156	TC32	viability	CTTTATCGTGATTCCCCCGTTGG	GRM1	ENSG00000152822	0.18635996767981555	[1079]	[984,1171,1287,1135]	3	hSpCas9	negative selection	9426518
146159460	146159483	6	-	27260156	TC32	viability	CTCGGAGTTTGCGCAAGAGTCGG	GRM1	ENSG00000152822	-0.038383973884729694	[799]	[628,709,720,846]	0	hSpCas9	negative selection	9426519
146352394	146352417	6	-	27260156	TC32	viability	CAGCAGCTTGCTGCCGTCGATGG	GRM1	ENSG00000152822	0.5494915861181073	[363]	[624,325,643,448]	8	hSpCas9	negative selection	9490776
146352381	146352404	6	+	27260156	TC32	viability	GATGCCATGAAGCCCATCGACGG	GRM1	ENSG00000152822	-0.3054021252332799	[881]	[638,503,613,958]	-5	hSpCas9	negative selection	9490777
146304647	146304670	6	+	27260156	TC32	viability	TTATGAGGTGGAAGCCAACGGGG	GRM1	ENSG00000152822	-0.6883338972029646	[539]	[354,195,339,398]	-8	hSpCas9	negative selection	9490778
146029682	146029705	6	-	27869803	HPAFII	viability after 27 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	1.2294808746891277	[90]	[91,128,NaN]	8	hSpCas9	negative selection	9593941
146159403	146159426	6	-	27869803	HPAFII	viability after 27 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	-0.03619935771154337	[471]	[307,186,NaN]	0	hSpCas9	negative selection	9593942
146304788	146304811	6	-	27869803	HPAFII	viability after 27 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-1.2164461929555654	[132]	[52,10,NaN]	-7	hSpCas9	negative selection	9593943
146352365	146352388	6	-	27869803	HPAFII	viability after 27 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	1.2111131705260556	[17]	[46,0,NaN]	8	hSpCas9	negative selection	9593944
146357570	146357593	6	+	27869803	HPAFII	viability after 27 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.27873054294993094	[318]	[281,137,NaN]	2	hSpCas9	negative selection	9593945
146386972	146386995	6	+	27869803	HPAFII	viability after 27 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.2029328849910563	[181]	[192,242,NaN]	8	hSpCas9	negative selection	9593946
146029682	146029705	6	-	27869803	HPAFII	viability after 15 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.7618571546693544	[90]	[208,138,NaN]	8	hSpCas9	negative selection	9676390
146159403	146159426	6	-	27869803	HPAFII	viability after 15 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.09809247387189224	[471]	[677,458,NaN]	1	hSpCas9	negative selection	9676391
146304788	146304811	6	-	27869803	HPAFII	viability after 15 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-0.3235298972063094	[132]	[194,63,NaN]	-4	hSpCas9	negative selection	9676392
146352365	146352388	6	-	27869803	HPAFII	viability after 15 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.40152168708904323	[17]	[56,5,NaN]	4	hSpCas9	negative selection	9676393
146357570	146357593	6	+	27869803	HPAFII	viability after 15 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.6358059708910556	[318]	[758,391,NaN]	7	hSpCas9	negative selection	9676394
146386972	146386995	6	+	27869803	HPAFII	viability after 15 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.217757726180002	[181]	[330,531,NaN]	9	hSpCas9	negative selection	9676395
146029682	146029705	6	-	27869803	ASPC1	viability after 36 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	-0.40710919844187554	[209]	[33,45,76]	-4	hSpCas9	negative selection	9758839
146159403	146159426	6	-	27869803	ASPC1	viability after 36 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.001046340454854855	[1449]	[504,361,616]	0	hSpCas9	negative selection	9758840
146304788	146304811	6	-	27869803	ASPC1	viability after 36 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	1.4727274447611522	[314]	[12,124,649]	9	hSpCas9	negative selection	9758841
146352365	146352388	6	-	27869803	ASPC1	viability after 36 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.1975454977814568	[39]	[6,19,18]	2	hSpCas9	negative selection	9758842
146357570	146357593	6	+	27869803	ASPC1	viability after 36 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.6960907761148399	[652]	[85,662,330]	6	hSpCas9	negative selection	9758843
146386972	146386995	6	+	27869803	ASPC1	viability after 36 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.006229563155291	[772]	[290,704,582]	8	hSpCas9	negative selection	9758844
146029682	146029705	6	-	27869803	PATU8988S	viability after 35 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.060991457899040036	[207]	[38,135,NaN]	0	hSpCas9	negative selection	9841288
146159403	146159426	6	-	27869803	PATU8988S	viability after 35 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.5031608145391915	[1067]	[670,547,NaN]	5	hSpCas9	negative selection	9841289
146304788	146304811	6	-	27869803	PATU8988S	viability after 35 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.46349990269106156	[235]	[157,103,NaN]	5	hSpCas9	negative selection	9841290
146352365	146352388	6	-	27869803	PATU8988S	viability after 35 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-2.7737778395684796	[33]	[2,0,NaN]	-9	hSpCas9	negative selection	9841291
146357570	146357593	6	+	27869803	PATU8988S	viability after 35 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.7317509074539843	[751]	[484,520,NaN]	7	hSpCas9	negative selection	9841292
146386972	146386995	6	+	27869803	PATU8988S	viability after 35 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.07313773347831756	[503]	[171,213,NaN]	0	hSpCas9	negative selection	9841293
146029682	146029705	6	-	27869803	PATU8988S	viability after 31 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	-0.22676183206493583	[207]	[47,99,NaN]	-3	hSpCas9	negative selection	9923737
146159403	146159426	6	-	27869803	PATU8988S	viability after 31 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.6679228905151358	[1067]	[658,698,NaN]	7	hSpCas9	negative selection	9923738
146304788	146304811	6	-	27869803	PATU8988S	viability after 31 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	0.3669797920594652	[235]	[123,117,NaN]	4	hSpCas9	negative selection	9923739
146352365	146352388	6	-	27869803	PATU8988S	viability after 31 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	-0.1952437530450135	[33]	[17,3,NaN]	-2	hSpCas9	negative selection	9923740
146357570	146357593	6	+	27869803	PATU8988S	viability after 31 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.546740087333512	[751]	[353,544,NaN]	6	hSpCas9	negative selection	9923741
146386972	146386995	6	+	27869803	PATU8988S	viability after 31 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.6157424762905542	[503]	[80,194,NaN]	-6	hSpCas9	negative selection	9923742
146029682	146029705	6	-	27869803	HPAFII	viability after 35 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	0.8264813081610216	[90]	[60,104,NaN]	5	hSpCas9	negative selection	10006186
146159403	146159426	6	-	27869803	HPAFII	viability after 35 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.2384710114528812	[471]	[311,247,NaN]	1	hSpCas9	negative selection	10006187
146304788	146304811	6	-	27869803	HPAFII	viability after 35 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-1.7464269124692018	[132]	[36,0,NaN]	-7	hSpCas9	negative selection	10006188
146352365	146352388	6	-	27869803	HPAFII	viability after 35 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	1.2131442094679055	[17]	[38,0,NaN]	7	hSpCas9	negative selection	10006189
146357570	146357593	6	+	27869803	HPAFII	viability after 35 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.7033564073958656	[318]	[293,227,NaN]	4	hSpCas9	negative selection	10006190
146386972	146386995	6	+	27869803	HPAFII	viability after 35 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.3408764801532935	[181]	[183,288,NaN]	8	hSpCas9	negative selection	10006191
146029682	146029705	6	-	27869803	HPAFII	viability after 31 days	GCACTTTCTCGGCCGGAGGCTGG	GRM1	ENSG00000152822	1.3838002702898735	[90]	[116,150,NaN]	8	hSpCas9	negative selection	10088635
146159403	146159426	6	-	27869803	HPAFII	viability after 31 days	TGTCAGAATGGGCGATACAGAGG	GRM1	ENSG00000152822	0.15397126434472397	[471]	[310,276,NaN]	1	hSpCas9	negative selection	10088636
146304788	146304811	6	-	27869803	HPAFII	viability after 31 days	GGTGTCCTGGAAGGCGGCACTGG	GRM1	ENSG00000152822	-2.424157084050604	[132]	[22,3,NaN]	-8	hSpCas9	negative selection	10088637
146352365	146352388	6	-	27869803	HPAFII	viability after 31 days	TGGCATCGCAGAGGCCCACGTGG	GRM1	ENSG00000152822	0.6743538844798147	[17]	[29,0,NaN]	5	hSpCas9	negative selection	10088638
146357570	146357593	6	+	27869803	HPAFII	viability after 31 days	ACTATGTGCACGTTGGAACCTGG	GRM1	ENSG00000152822	0.6401168326236909	[318]	[334,217,NaN]	5	hSpCas9	negative selection	10088639
146386972	146386995	6	+	27869803	HPAFII	viability after 31 days	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.3671574929435226	[181]	[184,348,NaN]	8	hSpCas9	negative selection	10088640
146399003	146399026	6	-	28162770	P31FUJ	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-1.9769632999847888	[66]	[19]	-8	hSpCas9	negative selection	10165906
146399147	146399170	6	-	28162770	P31FUJ	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.066585251749628	[302]	[84]	-8	hSpCas9	negative selection	10165907
146029733	146029756	6	+	28162770	P31FUJ	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.29127805415975505	[120]	[173]	3	hSpCas9	negative selection	10165908
146159380	146159403	6	+	28162770	P31FUJ	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.6665938546472157	[192]	[359]	7	hSpCas9	negative selection	10165909
146159424	146159447	6	+	28162770	P31FUJ	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-0.2790958566883137	[94]	[91]	-3	hSpCas9	negative selection	10165910
146304730	146304753	6	+	28162770	P31FUJ	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.652038597574201	[188]	[348]	7	hSpCas9	negative selection	10165911
146386972	146386995	6	+	28162770	P31FUJ	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.4401271776618849	[126]	[109]	-4	hSpCas9	negative selection	10165912
146398884	146398907	6	+	28162770	P31FUJ	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.12724126304453287	[126]	[162]	1	hSpCas9	negative selection	10165913
146398913	146398936	6	-	28162770	P31FUJ	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.31235928824880266	[391]	[571]	3	hSpCas9	negative selection	10165914
146398956	146398979	6	-	28162770	P31FUJ	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.2232161555851806	[599]	[603]	-2	hSpCas9	negative selection	10165915
146399003	146399026	6	-	28162770	TF1	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10335272
146399147	146399170	6	-	28162770	TF1	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10335273
146029733	146029756	6	+	28162770	TF1	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10335274
146159380	146159403	6	+	28162770	TF1	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10335275
146159424	146159447	6	+	28162770	TF1	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10335276
146304730	146304753	6	+	28162770	TF1	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10335277
146386972	146386995	6	+	28162770	TF1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10335278
146398884	146398907	6	+	28162770	TF1	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10335279
146398913	146398936	6	-	28162770	TF1	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10335280
146398956	146398979	6	-	28162770	TF1	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	NaN	[NaN]	[437]	1	hSpCas9	negative selection	10335281
146399003	146399026	6	-	28162770	SKM1	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-3.0850361038557996	[23]	[4]	-9	hSpCas9	negative selection	10504638
146399147	146399170	6	-	28162770	SKM1	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-6.930526154800175	[68]	[0]	-9	hSpCas9	negative selection	10504639
146029733	146029756	6	+	28162770	SKM1	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.19736362684492564	[36]	[74]	2	hSpCas9	negative selection	10504640
146159380	146159403	6	+	28162770	SKM1	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.4923132127554816	[75]	[188]	5	hSpCas9	negative selection	10504641
146159424	146159447	6	+	28162770	SKM1	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.38745166760694444	[31]	[73]	4	hSpCas9	negative selection	10504642
146304730	146304753	6	+	28162770	SKM1	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.24838762986939245	[59]	[125]	2	hSpCas9	negative selection	10504643
146386972	146386995	6	+	28162770	SKM1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.2370391973008492	[31]	[47]	-2	hSpCas9	negative selection	10504644
146398884	146398907	6	+	28162770	SKM1	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.31044859800164415	[25]	[56]	3	hSpCas9	negative selection	10504645
146398913	146398936	6	-	28162770	SKM1	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.16847552785948788	[75]	[150]	1	hSpCas9	negative selection	10504646
146398956	146398979	6	-	28162770	SKM1	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.20880434875916887	[138]	[283]	2	hSpCas9	negative selection	10504647
146399003	146399026	6	-	28162770	SKM1	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-3.0850361038557996	[23]	[4]	-9	hSpCas9	negative selection	10674004
146399147	146399170	6	-	28162770	SKM1	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-6.930526154800175	[68]	[0]	-9	hSpCas9	negative selection	10674005
146029733	146029756	6	+	28162770	SKM1	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.19736362684492564	[36]	[74]	2	hSpCas9	negative selection	10674006
146159380	146159403	6	+	28162770	SKM1	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.4923132127554816	[75]	[188]	5	hSpCas9	negative selection	10674007
146159424	146159447	6	+	28162770	SKM1	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.38745166760694444	[31]	[73]	4	hSpCas9	negative selection	10674008
146304730	146304753	6	+	28162770	SKM1	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.24838762986939245	[59]	[125]	2	hSpCas9	negative selection	10674009
146386972	146386995	6	+	28162770	SKM1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.2370391973008492	[31]	[47]	-2	hSpCas9	negative selection	10674010
146398884	146398907	6	+	28162770	SKM1	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.31044859800164415	[25]	[56]	3	hSpCas9	negative selection	10674011
146398913	146398936	6	-	28162770	SKM1	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.16847552785948788	[75]	[150]	1	hSpCas9	negative selection	10674012
146398956	146398979	6	-	28162770	SKM1	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.20880434875916887	[138]	[283]	2	hSpCas9	negative selection	10674013
146399003	146399026	6	-	28162770	PL21	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-0.6363616532278005	[74]	[20]	-4	hSpCas9	negative selection	10843370
146399147	146399170	6	-	28162770	PL21	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-1.3745545507780088	[279]	[46]	-7	hSpCas9	negative selection	10843371
146029733	146029756	6	+	28162770	PL21	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.212630558672517	[114]	[57]	2	hSpCas9	negative selection	10843372
146159380	146159403	6	+	28162770	PL21	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.3777825290924692	[289]	[327]	9	hSpCas9	negative selection	10843373
146159424	146159447	6	+	28162770	PL21	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-1.7606897882300019	[108]	[13]	-8	hSpCas9	negative selection	10843374
146304730	146304753	6	+	28162770	PL21	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	1.4317309726722327	[200]	[235]	9	hSpCas9	negative selection	10843375
146386972	146386995	6	+	28162770	PL21	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.4923203659826303	[48]	[29]	4	hSpCas9	negative selection	10843376
146398884	146398907	6	+	28162770	PL21	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-0.5547478876741485	[80]	[23]	-4	hSpCas9	negative selection	10843377
146398913	146398936	6	-	28162770	PL21	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.14485717898813044	[265]	[127]	1	hSpCas9	negative selection	10843378
146398956	146398979	6	-	28162770	PL21	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.11410774331641815	[561]	[225]	-1	hSpCas9	negative selection	10843379
146399003	146399026	6	-	28162770	P31FUJ	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-1.9769632999847888	[66]	[19]	-8	hSpCas9	negative selection	11012736
146399147	146399170	6	-	28162770	P31FUJ	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.066585251749628	[302]	[84]	-8	hSpCas9	negative selection	11012737
146029733	146029756	6	+	28162770	P31FUJ	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.29127805415975505	[120]	[173]	3	hSpCas9	negative selection	11012738
146159380	146159403	6	+	28162770	P31FUJ	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.6665938546472157	[192]	[359]	7	hSpCas9	negative selection	11012739
146159424	146159447	6	+	28162770	P31FUJ	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-0.2790958566883137	[94]	[91]	-3	hSpCas9	negative selection	11012740
146304730	146304753	6	+	28162770	P31FUJ	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.652038597574201	[188]	[348]	7	hSpCas9	negative selection	11012741
146386972	146386995	6	+	28162770	P31FUJ	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.4401271776618849	[126]	[109]	-4	hSpCas9	negative selection	11012742
146398884	146398907	6	+	28162770	P31FUJ	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.12724126304453287	[126]	[162]	1	hSpCas9	negative selection	11012743
146398913	146398936	6	-	28162770	P31FUJ	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.31235928824880266	[391]	[571]	3	hSpCas9	negative selection	11012744
146398956	146398979	6	-	28162770	P31FUJ	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.2232161555851806	[599]	[603]	-2	hSpCas9	negative selection	11012745
146399003	146399026	6	-	28162770	OCIAML5	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-7.041891129744014	[72]	[0]	-9	hSpCas9	negative selection	11182102
146399147	146399170	6	-	28162770	OCIAML5	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.9571832766782116	[184]	[42]	-8	hSpCas9	negative selection	11182103
146029733	146029756	6	+	28162770	OCIAML5	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.01787288857162994	[57]	[105]	0	hSpCas9	negative selection	11182104
146159380	146159403	6	+	28162770	OCIAML5	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.1712659329666268	[91]	[373]	8	hSpCas9	negative selection	11182105
146159424	146159447	6	+	28162770	OCIAML5	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.3269035701813223	[52]	[119]	2	hSpCas9	negative selection	11182106
146304730	146304753	6	+	28162770	OCIAML5	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	1.2496288262053539	[88]	[381]	9	hSpCas9	negative selection	11182107
146386972	146386995	6	+	28162770	OCIAML5	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.7624293583793205	[77]	[82]	-5	hSpCas9	negative selection	11182108
146398884	146398907	6	+	28162770	OCIAML5	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-0.2177160431806774	[66]	[103]	-1	hSpCas9	negative selection	11182109
146398913	146398936	6	-	28162770	OCIAML5	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.7380854859597228	[184]	[556]	6	hSpCas9	negative selection	11182110
146398956	146398979	6	-	28162770	OCIAML5	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.11767952079956712	[335]	[558]	-1	hSpCas9	negative selection	11182111
146399003	146399026	6	-	28162770	EOL1	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-0.5221353543247744	[168]	[61]	-4	hSpCas9	negative selection	11351468
146399147	146399170	6	-	28162770	EOL1	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-3.963727145870637	[384]	[12]	-9	hSpCas9	negative selection	11351469
146029733	146029756	6	+	28162770	EOL1	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.18219898070742513	[178]	[106]	1	hSpCas9	negative selection	11351470
146159380	146159403	6	+	28162770	EOL1	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.2822765878857438	[397]	[509]	9	hSpCas9	negative selection	11351471
146159424	146159447	6	+	28162770	EOL1	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-0.7705976469010447	[135]	[41]	-5	hSpCas9	negative selection	11351472
146304730	146304753	6	+	28162770	EOL1	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.011378729443714042	[402]	[213]	0	hSpCas9	negative selection	11351473
146386972	146386995	6	+	28162770	EOL1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.09631411983701432	[86]	[48]	0	hSpCas9	negative selection	11351474
146398884	146398907	6	+	28162770	EOL1	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.9245477715705345	[105]	[105]	7	hSpCas9	negative selection	11351475
146398913	146398936	6	-	28162770	EOL1	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.3226321375681812	[427]	[281]	3	hSpCas9	negative selection	11351476
146398956	146398979	6	-	28162770	EOL1	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.38271063451994247	[635]	[256]	-3	hSpCas9	negative selection	11351477
146399003	146399026	6	-	28162770	MOLM13	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-2.8966830507512773	[102]	[9]	-8	hSpCas9	negative selection	11520834
146399147	146399170	6	-	28162770	MOLM13	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.359929643072741	[425]	[59]	-8	hSpCas9	negative selection	11520835
146029733	146029756	6	+	28162770	MOLM13	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	1.5244729099109464	[149]	[311]	9	hSpCas9	negative selection	11520836
146159380	146159403	6	+	28162770	MOLM13	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.2001935983409222	[309]	[514]	8	hSpCas9	negative selection	11520837
146159424	146159447	6	+	28162770	MOLM13	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	-1.7291474655149748	[187]	[40]	-7	hSpCas9	negative selection	11520838
146304730	146304753	6	+	28162770	MOLM13	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.8815336455235564	[258]	[344]	6	hSpCas9	negative selection	11520839
146386972	146386995	6	+	28162770	MOLM13	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-1.8089508238142455	[125]	[25]	-7	hSpCas9	negative selection	11520840
146398884	146398907	6	+	28162770	MOLM13	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-1.918169050762499	[114]	[21]	-7	hSpCas9	negative selection	11520841
146398913	146398936	6	-	28162770	MOLM13	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.47923435513858825	[379]	[382]	3	hSpCas9	negative selection	11520842
146398956	146398979	6	-	28162770	MOLM13	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.01932850115165108	[805]	[574]	0	hSpCas9	negative selection	11520843
146399003	146399026	6	-	28162770	HEL	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-2.0577008861407355	[103]	[15]	-8	hSpCas9	negative selection	11690200
146399147	146399170	6	-	28162770	HEL	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.6318835481086484	[299]	[30]	-8	hSpCas9	negative selection	11690201
146029733	146029756	6	+	28162770	HEL	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	1.1350193302116611	[149]	[210]	8	hSpCas9	negative selection	11690202
146159380	146159403	6	+	28162770	HEL	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.1224491780276455	[288]	[402]	8	hSpCas9	negative selection	11690203
146159424	146159447	6	+	28162770	HEL	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.35214870364600176	[147]	[120]	3	hSpCas9	negative selection	11690204
146304730	146304753	6	+	28162770	HEL	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.9787880351323721	[243]	[307]	8	hSpCas9	negative selection	11690205
146386972	146386995	6	+	28162770	HEL	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.2133460397444431	[100]	[74]	1	hSpCas9	negative selection	11690206
146398884	146398907	6	+	28162770	HEL	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	0.2153176082656807	[77]	[57]	1	hSpCas9	negative selection	11690207
146398913	146398936	6	-	28162770	HEL	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.3829247289342056	[357]	[298]	3	hSpCas9	negative selection	11690208
146398956	146398979	6	-	28162770	HEL	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.47631383964340623	[605]	[278]	-3	hSpCas9	negative selection	11690209
146399003	146399026	6	-	28162770	MV411	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-0.5769908846337701	[84]	[47]	-4	hSpCas9	negative selection	11859566
146399147	146399170	6	-	28162770	MV411	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-2.8372851281226517	[262]	[30]	-9	hSpCas9	negative selection	11859567
146029733	146029756	6	+	28162770	MV411	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	-0.006319041463007546	[123]	[103]	0	hSpCas9	negative selection	11859568
146159380	146159403	6	+	28162770	MV411	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.3686511377518558	[250]	[545]	9	hSpCas9	negative selection	11859569
146159424	146159447	6	+	28162770	MV411	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.6624750500616191	[71]	[95]	6	hSpCas9	negative selection	11859570
146304730	146304753	6	+	28162770	MV411	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.8420826049012708	[197]	[298]	7	hSpCas9	negative selection	11859571
146386972	146386995	6	+	28162770	MV411	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-1.3228781739739794	[97]	[32]	-7	hSpCas9	negative selection	11859572
146398884	146398907	6	+	28162770	MV411	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	1.3227256780870122	[55]	[117]	9	hSpCas9	negative selection	11859573
146398913	146398936	6	-	28162770	MV411	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.14589952432071318	[308]	[287]	1	hSpCas9	negative selection	11859574
146398956	146398979	6	-	28162770	MV411	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.31770350902563704	[505]	[341]	-2	hSpCas9	negative selection	11859575
146399003	146399026	6	-	28162770	MONOMAC1	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-2.232660756790275	[40]	[9]	-9	hSpCas9	negative selection	12028932
146399147	146399170	6	-	28162770	MONOMAC1	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-1.1735778742355647	[121]	[61]	-7	hSpCas9	negative selection	12028933
146029733	146029756	6	+	28162770	MONOMAC1	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.7845846236255918	[78]	[155]	7	hSpCas9	negative selection	12028934
146159380	146159403	6	+	28162770	MONOMAC1	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	1.1615201698185311	[139]	[358]	8	hSpCas9	negative selection	12028935
146159424	146159447	6	+	28162770	MONOMAC1	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.04397125244424127	[54]	[64]	0	hSpCas9	negative selection	12028936
146304730	146304753	6	+	28162770	MONOMAC1	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.6119148599323799	[128]	[225]	6	hSpCas9	negative selection	12028937
146386972	146386995	6	+	28162770	MONOMAC1	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	-0.4085409522532656	[65]	[56]	-4	hSpCas9	negative selection	12028938
146398884	146398907	6	+	28162770	MONOMAC1	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	-0.4431974343289513	[50]	[42]	-4	hSpCas9	negative selection	12028939
146398913	146398936	6	-	28162770	MONOMAC1	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	0.785369092925708	[164]	[325]	7	hSpCas9	negative selection	12028940
146398956	146398979	6	-	28162770	MONOMAC1	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.009414030407872698	[350]	[404]	0	hSpCas9	negative selection	12028941
146399003	146399026	6	-	28162770	OCIAML2	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-2.4706298252421615	[16]	[16]	-8	hSpCas9	negative selection	12198298
146399147	146399170	6	-	28162770	OCIAML2	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-3.6670270380456644	[54]	[23]	-9	hSpCas9	negative selection	12198299
146029733	146029756	6	+	28162770	OCIAML2	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	-0.0018603420255277614	[27]	[154]	0	hSpCas9	negative selection	12198300
146159380	146159403	6	+	28162770	OCIAML2	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.5056541057840314	[45]	[361]	5	hSpCas9	negative selection	12198301
146159424	146159447	6	+	28162770	OCIAML2	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.762030931548114	[9]	[93]	7	hSpCas9	negative selection	12198302
146304730	146304753	6	+	28162770	OCIAML2	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.8101409448884414	[31]	[310]	7	hSpCas9	negative selection	12198303
146386972	146386995	6	+	28162770	OCIAML2	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	1.326383152593984	[9]	[138]	9	hSpCas9	negative selection	12198304
146398884	146398907	6	+	28162770	OCIAML2	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	1.3273263988131934	[10]	[152]	9	hSpCas9	negative selection	12198305
146398913	146398936	6	-	28162770	OCIAML2	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	-0.2913061257975994	[67]	[307]	-2	hSpCas9	negative selection	12198306
146398956	146398979	6	-	28162770	OCIAML2	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	-0.076851445335121	[93]	[493]	0	hSpCas9	negative selection	12198307
146399003	146399026	6	-	28162770	OCIAML3	viability	GAGGCGCTGGAGGTAGCAGGAGG	GRM1	ENSG00000152822	-0.8284728939611863	[19]	[33]	-6	hSpCas9	negative selection	12367664
146399147	146399170	6	-	28162770	OCIAML3	viability	GGCAATGATCACCTGAGCCCAGG	GRM1	ENSG00000152822	-1.4087927678572554	[72]	[82]	-7	hSpCas9	negative selection	12367665
146029733	146029756	6	+	28162770	OCIAML3	viability	GCAGTATGGCATCCAGAGGGTGG	GRM1	ENSG00000152822	0.7483845571229149	[27]	[141]	6	hSpCas9	negative selection	12367666
146159380	146159403	6	+	28162770	OCIAML3	viability	AAAGAGCTGGCTGCCCAGGAAGG	GRM1	ENSG00000152822	0.42705397520366645	[50]	[206]	4	hSpCas9	negative selection	12367667
146159424	146159447	6	+	28162770	OCIAML3	viability	CAAAATCTACAGCAACGCTGGGG	GRM1	ENSG00000152822	0.4712838199275561	[26]	[112]	4	hSpCas9	negative selection	12367668
146304730	146304753	6	+	28162770	OCIAML3	viability	TGAGGCTGGACACTAACACGAGG	GRM1	ENSG00000152822	0.7602209464665093	[52]	[270]	6	hSpCas9	negative selection	12367669
146386972	146386995	6	+	28162770	OCIAML3	viability	GCAAAGCTTGTGACTTGGGATGG	GRM1	ENSG00000152822	0.5279828840544474	[16]	[73]	5	hSpCas9	negative selection	12367670
146398884	146398907	6	+	28162770	OCIAML3	viability	ACTGTACCGGGACACACCAGTGG	GRM1	ENSG00000152822	1.1501534552462467	[9]	[66]	8	hSpCas9	negative selection	12367671
146398913	146398936	6	-	28162770	OCIAML3	viability	GTAGCAGAGCTCCCGACTGGAGG	GRM1	ENSG00000152822	1.405992359675837	[85]	[687]	9	hSpCas9	negative selection	12367672
146398956	146398979	6	-	28162770	OCIAML3	viability	TGAATGGGCACACATAACCAAGG	GRM1	ENSG00000152822	0.21749097546061646	[148]	[522]	2	hSpCas9	negative selection	12367673