Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10013
• Symbol: HDAC6
• Description: histone deacetylase 6

DataSource: http://genomecrispr.dkfz.de/#!/results/HDAC6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48802945	48802968	X	+	26472758	Jiyoye	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.6117141380295229	[150]	[173]	4	hSpCas9	negative selection	69774
48822686	48822709	X	-	26472758	Jiyoye	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.1555571718318173	[160]	[108]	-1	hSpCas9	negative selection	69775
48815894	48815917	X	+	26472758	Jiyoye	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	0.7523108675545611	[73]	[93]	5	hSpCas9	negative selection	69776
48822673	48822696	X	-	26472758	Jiyoye	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-2.5580592003334504	[163]	[20]	-9	hSpCas9	negative selection	69777
48802762	48802785	X	-	26472758	Jiyoye	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.10551968164477232	[370]	[300]	0	hSpCas9	negative selection	69778
48808116	48808139	X	+	26472758	Jiyoye	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.04944656519066415	[254]	[198]	0	hSpCas9	negative selection	69779
48814511	48814534	X	-	26472758	Jiyoye	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	-0.5286942810744111	[175]	[91]	-4	hSpCas9	negative selection	69780
48814840	48814863	X	-	26472758	Jiyoye	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	69781
48816603	48816626	X	-	26472758	Jiyoye	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.6452920383882621	[167]	[80]	-4	hSpCas9	negative selection	69782
48822651	48822674	X	-	26472758	Jiyoye	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.6635151347656592	[71]	[85]	5	hSpCas9	negative selection	69783
48802945	48802968	X	+	26472758	KBM7	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.3304078492618008	[721,509]	[405,317]	3	hSpCas9	negative selection	260892
48822686	48822709	X	-	26472758	KBM7	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.3232835703567287	[495,551]	[180,214]	-3	hSpCas9	negative selection	260893
48815894	48815917	X	+	26472758	KBM7	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.5505065510928208	[823,657]	[201,266]	-5	hSpCas9	negative selection	260894
48822673	48822696	X	-	26472758	KBM7	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-3.5978204754404657	[531,413]	[13,21]	-9	hSpCas9	negative selection	260895
48802762	48802785	X	-	26472758	KBM7	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.23868576641820316	[1525,1031]	[934,487]	2	hSpCas9	negative selection	260896
48808116	48808139	X	+	26472758	KBM7	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.2521902292590551	[561,330]	[241,246]	2	hSpCas9	negative selection	260897
48814511	48814534	X	-	26472758	KBM7	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.11182484247182156	[740,918]	[524,341]	1	hSpCas9	negative selection	260898
48814840	48814863	X	-	26472758	KBM7	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.6122849944677102	[64,109]	[22,31]	-5	hSpCas9	negative selection	260899
48816603	48816626	X	-	26472758	KBM7	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.23873651278484448	[646,464]	[383,233]	2	hSpCas9	negative selection	260900
48822651	48822674	X	-	26472758	KBM7	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.6773683676127737	[335,411]	[407,175]	7	hSpCas9	negative selection	260901
48802945	48802968	X	+	26472758	Raji	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.3749690334385801	[421]	[126]	3	hSpCas9	negative selection	452010
48822686	48822709	X	-	26472758	Raji	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-1.1346912518245482	[245]	[25]	-7	hSpCas9	negative selection	452011
48815894	48815917	X	+	26472758	Raji	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.4140138365700907	[332]	[28]	-7	hSpCas9	negative selection	452012
48822673	48822696	X	-	26472758	Raji	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-2.377052089393592	[290]	[12]	-9	hSpCas9	negative selection	452013
48802762	48802785	X	-	26472758	Raji	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.27150291513470615	[663]	[185]	2	hSpCas9	negative selection	452014
48808116	48808139	X	+	26472758	Raji	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.4751153198740866	[309]	[99]	4	hSpCas9	negative selection	452015
48814511	48814534	X	-	26472758	Raji	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.20150571273814954	[355]	[94]	2	hSpCas9	negative selection	452016
48814840	48814863	X	-	26472758	Raji	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.9800793058767399	[50]	[5]	-6	hSpCas9	negative selection	452017
48816603	48816626	X	-	26472758	Raji	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.07375275749231935	[433]	[105]	0	hSpCas9	negative selection	452018
48822651	48822674	X	-	26472758	Raji	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.31156901390862757	[245]	[45]	-3	hSpCas9	negative selection	452019
48802945	48802968	X	+	26472758	K562	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.1565237045642892	[625]	[588]	1	hSpCas9	negative selection	643128
48822686	48822709	X	-	26472758	K562	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.928819007816701	[326]	[144]	-5	hSpCas9	negative selection	643129
48815894	48815917	X	+	26472758	K562	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-2.7866973967039907	[702]	[85]	-8	hSpCas9	negative selection	643130
48822673	48822696	X	-	26472758	K562	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-3.7361289096673804	[441]	[27]	-9	hSpCas9	negative selection	643131
48802762	48802785	X	-	26472758	K562	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.1420335666379613	[904]	[842]	1	hSpCas9	negative selection	643132
48808116	48808139	X	+	26472758	K562	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.8567317165325586	[417]	[638]	7	hSpCas9	negative selection	643133
48814511	48814534	X	-	26472758	K562	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	-0.4590807902237033	[766]	[470]	-3	hSpCas9	negative selection	643134
48814840	48814863	X	-	26472758	K562	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-2.965034637962503	[36]	[3]	-8	hSpCas9	negative selection	643135
48816603	48816626	X	-	26472758	K562	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.6365012890758124	[522]	[283]	-4	hSpCas9	negative selection	643136
48822651	48822674	X	-	26472758	K562	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.10976920097166493	[302]	[275]	0	hSpCas9	negative selection	643137
48801923	48801946	X	+	26627737	DLD1	viability	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.19066369113148302	[598]	[145,317,185]	2	hSpCas9	negative selection	845832
48802772	48802795	X	-	26627737	DLD1	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.6389076352913177	[215]	[108,122,86]	6	hSpCas9	negative selection	845833
48802945	48802968	X	+	26627737	DLD1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.082140336522517	[228]	[109,208,139]	8	hSpCas9	negative selection	845834
48803202	48803225	X	-	26627737	DLD1	viability	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.3698342697494259	[346]	[187,169,73]	4	hSpCas9	negative selection	845835
48805627	48805650	X	+	26627737	DLD1	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.32696795144262913	[1261]	[591,276,590]	3	hSpCas9	negative selection	845836
48806422	48806445	X	-	26627737	DLD1	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.2598968738586569	[1495]	[639,777,309]	2	hSpCas9	negative selection	845837
48801923	48801946	X	+	26627737	GBM cells	viability after 5 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.24516739219263495	[246]	[127,185]	4	hSpCas9	negative selection	928147
48802772	48802795	X	-	26627737	GBM cells	viability after 5 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.9263946113077928	[77]	[94,63]	9	hSpCas9	negative selection	928148
48802945	48802968	X	+	26627737	GBM cells	viability after 5 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.4907383059732444	[168]	[72,55]	-7	hSpCas9	negative selection	928149
48803202	48803225	X	-	26627737	GBM cells	viability after 5 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.3900942292862246	[142]	[110,89]	6	hSpCas9	negative selection	928150
48805627	48805650	X	+	26627737	GBM cells	viability after 5 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.2485488989428899	[721]	[421,497]	4	hSpCas9	negative selection	928151
48806422	48806445	X	-	26627737	GBM cells	viability after 5 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.4798730981237972	[523]	[207,194]	-6	hSpCas9	negative selection	928152
48801923	48801946	X	+	26627737	GBM cells	viability after 13 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.16869417003504514	[246]	[191,116]	2	hSpCas9	negative selection	1010462
48802772	48802795	X	-	26627737	GBM cells	viability after 13 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	1.0255536749637786	[77]	[121,56]	9	hSpCas9	negative selection	1010463
48802945	48802968	X	+	26627737	GBM cells	viability after 13 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.038067807591504965	[168]	[113,77]	0	hSpCas9	negative selection	1010464
48803202	48803225	X	-	26627737	GBM cells	viability after 13 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.16985884704754262	[142]	[79,59]	-2	hSpCas9	negative selection	1010465
48805627	48805650	X	+	26627737	GBM cells	viability after 13 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.5847834166106052	[721]	[629,552]	7	hSpCas9	negative selection	1010466
48806422	48806445	X	-	26627737	GBM cells	viability after 13 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.027564622626551127	[523]	[291,287]	0	hSpCas9	negative selection	1010467
48801923	48801946	X	+	26627737	GBM cells	viability after 21 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.8315922199192365	[246]	[254,223]	8	hSpCas9	negative selection	1092777
48802772	48802795	X	-	26627737	GBM cells	viability after 21 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.584020559357489	[77]	[62,63]	6	hSpCas9	negative selection	1092778
48802945	48802968	X	+	26627737	GBM cells	viability after 21 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.09651518644277862	[168]	[105,90]	1	hSpCas9	negative selection	1092779
48803202	48803225	X	-	26627737	GBM cells	viability after 21 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.11931837998269512	[142]	[70,71]	-1	hSpCas9	negative selection	1092780
48805627	48805650	X	+	26627737	GBM cells	viability after 21 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.8250398433836941	[721]	[708,681]	7	hSpCas9	negative selection	1092781
48806422	48806445	X	-	26627737	GBM cells	viability after 21 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.308198792455439	[523]	[352,351]	3	hSpCas9	negative selection	1092782
48801923	48801946	X	+	26627737	RPE1	viability after 9 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	2.09905263127965	[437]	[545,640]	9	hSpCas9	negative selection	1175092
48802772	48802795	X	-	26627737	RPE1	viability after 9 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.48030750799612315	[451]	[151,255]	3	hSpCas9	negative selection	1175093
48802945	48802968	X	+	26627737	RPE1	viability after 9 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.8136821078878391	[443]	[218,276]	5	hSpCas9	negative selection	1175094
48803202	48803225	X	-	26627737	RPE1	viability after 9 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.7637490437514105	[688]	[42,89]	-8	hSpCas9	negative selection	1175095
48805627	48805650	X	+	26627737	RPE1	viability after 9 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.8439519961948247	[2475]	[897,2027]	5	hSpCas9	negative selection	1175096
48806422	48806445	X	-	26627737	RPE1	viability after 9 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.6136422580929697	[1148]	[628,448]	4	hSpCas9	negative selection	1175097
48801923	48801946	X	+	26627737	RPE1	viability after 12 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	2.192710095757072	[437]	[519,556]	9	hSpCas9	negative selection	1257407
48802772	48802795	X	-	26627737	RPE1	viability after 12 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.16036123041865624	[451]	[108,163]	1	hSpCas9	negative selection	1257408
48802945	48802968	X	+	26627737	RPE1	viability after 12 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.7443146090757815	[443]	[193,205]	5	hSpCas9	negative selection	1257409
48803202	48803225	X	-	26627737	RPE1	viability after 12 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.4710897591932948	[688]	[75,56]	-7	hSpCas9	negative selection	1257410
48805627	48805650	X	+	26627737	RPE1	viability after 12 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.7474709437811631	[2475]	[905,1339]	5	hSpCas9	negative selection	1257411
48806422	48806445	X	-	26627737	RPE1	viability after 12 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.6978744556323928	[1148]	[372,635]	4	hSpCas9	negative selection	1257412
48801923	48801946	X	+	26627737	RPE1	viability after 15 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	2.415843514737091	[437]	[763,561]	9	hSpCas9	negative selection	1339722
48802772	48802795	X	-	26627737	RPE1	viability after 15 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-1.1052589869278369	[451]	[6,109]	-6	hSpCas9	negative selection	1339723
48802945	48802968	X	+	26627737	RPE1	viability after 15 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.608635852639914	[443]	[246,137]	4	hSpCas9	negative selection	1339724
48803202	48803225	X	-	26627737	RPE1	viability after 15 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.5843439205591703	[688]	[8,118]	-7	hSpCas9	negative selection	1339725
48805627	48805650	X	+	26627737	RPE1	viability after 15 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.884818251088672	[2475]	[993,1581]	5	hSpCas9	negative selection	1339726
48806422	48806445	X	-	26627737	RPE1	viability after 15 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.21117260040896157	[1148]	[220,525]	1	hSpCas9	negative selection	1339727
48801923	48801946	X	+	26627737	RPE1	viability after 18 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	2.0209881292435665	[437]	[340,627]	8	hSpCas9	negative selection	1422037
48802772	48802795	X	-	26627737	RPE1	viability after 18 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.2948395307627557	[451]	[109,191]	2	hSpCas9	negative selection	1422038
48802945	48802968	X	+	26627737	RPE1	viability after 18 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.8022843395823531	[443]	[294,116]	5	hSpCas9	negative selection	1422039
48803202	48803225	X	-	26627737	RPE1	viability after 18 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.064803458761902	[688]	[70,107]	-6	hSpCas9	negative selection	1422040
48805627	48805650	X	+	26627737	RPE1	viability after 18 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.0532894784173201	[2475]	[1012,1785]	6	hSpCas9	negative selection	1422041
48806422	48806445	X	-	26627737	RPE1	viability after 18 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.8835438539010778	[1148]	[573,569]	5	hSpCas9	negative selection	1422042
48801923	48801946	X	+	26627737	HeLa	viability after 8 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.8066680852162416	[325]	[229,137,363]	6	hSpCas9	negative selection	1504352
48802772	48802795	X	-	26627737	HeLa	viability after 8 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	1.692444464035232	[90]	[160,113,116]	9	hSpCas9	negative selection	1504353
48802945	48802968	X	+	26627737	HeLa	viability after 8 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.29038422478922277	[162]	[188,10,82]	2	hSpCas9	negative selection	1504354
48803202	48803225	X	-	26627737	HeLa	viability after 8 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.8025180684642945	[309]	[168,2,79]	-7	hSpCas9	negative selection	1504355
48805627	48805650	X	+	26627737	HeLa	viability after 8 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.9845726479666889	[779]	[1030,496,572]	7	hSpCas9	negative selection	1504356
48806422	48806445	X	-	26627737	HeLa	viability after 8 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.12173676137763612	[1142]	[445,585,344]	-1	hSpCas9	negative selection	1504357
48801923	48801946	X	+	26627737	HeLa	viability after 12 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.4363305419979154	[325]	[60,251,222]	4	hSpCas9	negative selection	1586667
48802772	48802795	X	-	26627737	HeLa	viability after 12 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.21539650644686725	[90]	[37,41,50]	2	hSpCas9	negative selection	1586668
48802945	48802968	X	+	26627737	HeLa	viability after 12 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.4893812154879127	[162]	[152,69,64]	4	hSpCas9	negative selection	1586669
48803202	48803225	X	-	26627737	HeLa	viability after 12 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.1320781720056199	[309]	[251,134,37]	1	hSpCas9	negative selection	1586670
48805627	48805650	X	+	26627737	HeLa	viability after 12 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.8373517315608198	[779]	[618,529,584]	6	hSpCas9	negative selection	1586671
48806422	48806445	X	-	26627737	HeLa	viability after 12 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.22407367862466065	[1142]	[583,285,360]	-2	hSpCas9	negative selection	1586672
48801923	48801946	X	+	26627737	HeLa	viability after 15 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.8406314506177162	[325]	[248,127,343]	6	hSpCas9	negative selection	1668982
48802772	48802795	X	-	26627737	HeLa	viability after 15 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	1.6101544367931926	[90]	[176,53,106]	9	hSpCas9	negative selection	1668983
48802945	48802968	X	+	26627737	HeLa	viability after 15 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.060985967401315344	[162]	[75,8,126]	0	hSpCas9	negative selection	1668984
48803202	48803225	X	-	26627737	HeLa	viability after 15 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.6669950846106587	[309]	[123,44,67]	-5	hSpCas9	negative selection	1668985
48805627	48805650	X	+	26627737	HeLa	viability after 15 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.1197684347617698	[779]	[751,679,632]	7	hSpCas9	negative selection	1668986
48806422	48806445	X	-	26627737	HeLa	viability after 15 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.05042772527579209	[1142]	[569,247,534]	0	hSpCas9	negative selection	1668987
48801923	48801946	X	+	26627737	HeLa	viability after 18 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.8291620243060678	[325]	[160,108,343]	6	hSpCas9	negative selection	1751297
48802772	48802795	X	-	26627737	HeLa	viability after 18 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	1.6288412320995114	[90]	[122,42,106]	9	hSpCas9	negative selection	1751298
48802945	48802968	X	+	26627737	HeLa	viability after 18 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.10991197074166048	[162]	[55,6,126]	1	hSpCas9	negative selection	1751299
48803202	48803225	X	-	26627737	HeLa	viability after 18 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.6121467220501576	[309]	[90,34,67]	-5	hSpCas9	negative selection	1751300
48805627	48805650	X	+	26627737	HeLa	viability after 18 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.1195388319724318	[779]	[505,560,632]	7	hSpCas9	negative selection	1751301
48806422	48806445	X	-	26627737	HeLa	viability after 18 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.045372236729518844	[1142]	[384,205,534]	0	hSpCas9	negative selection	1751302
48801923	48801946	X	+	26627737	HCT116	viability after 6 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	1.3868893474469988	[653]	[99,361]	7	hSpCas9	negative selection	1833612
48802772	48802795	X	-	26627737	HCT116	viability after 6 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.3746631556169334	[540]	[82,55]	-2	hSpCas9	negative selection	1833613
48802945	48802968	X	+	26627737	HCT116	viability after 6 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.2578169750807343	[461]	[130,21]	-1	hSpCas9	negative selection	1833614
48803202	48803225	X	-	26627737	HCT116	viability after 6 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	1.5918069375256885	[342]	[148,169]	7	hSpCas9	negative selection	1833615
48805627	48805650	X	+	26627737	HCT116	viability after 6 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.2076044343029944	[1035]	[564,271]	6	hSpCas9	negative selection	1833616
48806422	48806445	X	-	26627737	HCT116	viability after 6 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.4510946070761549	[1215]	[202,104]	-3	hSpCas9	negative selection	1833617
48801923	48801946	X	+	26627737	HCT116	viability after 8 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.5650619466495952	[379]	[328,233,365]	5	hSpCas9	negative selection	1915927
48802772	48802795	X	-	26627737	HCT116	viability after 8 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.7656361703212466	[181]	[60,56,58]	-7	hSpCas9	negative selection	1915928
48802945	48802968	X	+	26627737	HCT116	viability after 8 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.5797632779058555	[256]	[105,128,49]	-6	hSpCas9	negative selection	1915929
48803202	48803225	X	-	26627737	HCT116	viability after 8 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.3453302943677833	[118]	[50,86,110]	4	hSpCas9	negative selection	1915930
48805627	48805650	X	+	26627737	HCT116	viability after 8 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.3820770782056686	[707]	[549,549,426]	4	hSpCas9	negative selection	1915931
48806422	48806445	X	-	26627737	HCT116	viability after 8 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.5162717266870709	[397]	[295,356,287]	5	hSpCas9	negative selection	1915932
48801923	48801946	X	+	26627737	HCT116	viability after 9 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.661167776015535	[653]	[288,265]	5	hSpCas9	negative selection	1998242
48802772	48802795	X	-	26627737	HCT116	viability after 9 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-1.268254385905285	[540]	[64,55]	-7	hSpCas9	negative selection	1998243
48802945	48802968	X	+	26627737	HCT116	viability after 9 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-1.1466172165489628	[461]	[24,79]	-7	hSpCas9	negative selection	1998244
48803202	48803225	X	-	26627737	HCT116	viability after 9 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.42827478111725836	[342]	[138,11]	-3	hSpCas9	negative selection	1998245
48805627	48805650	X	+	26627737	HCT116	viability after 9 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.175685932185171	[1035]	[682,578]	7	hSpCas9	negative selection	1998246
48806422	48806445	X	-	26627737	HCT116	viability after 9 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.4118294501220082	[1215]	[417,442]	3	hSpCas9	negative selection	1998247
48801923	48801946	X	+	26627737	HCT116	viability after 12 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.8240072736241144	[379]	[275,377,413]	7	hSpCas9	negative selection	2080557
48802772	48802795	X	-	26627737	HCT116	viability after 12 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.5280647204442912	[181]	[104,41,47]	-5	hSpCas9	negative selection	2080558
48802945	48802968	X	+	26627737	HCT116	viability after 12 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.8497511784142814	[256]	[25,110,92]	-7	hSpCas9	negative selection	2080559
48803202	48803225	X	-	26627737	HCT116	viability after 12 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	1.3214586350776976	[118]	[123,167,179]	8	hSpCas9	negative selection	2080560
48805627	48805650	X	+	26627737	HCT116	viability after 12 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.41168959032516583	[707]	[468,489,527]	4	hSpCas9	negative selection	2080561
48806422	48806445	X	-	26627737	HCT116	viability after 12 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.682397657396355	[397]	[309,325,372]	6	hSpCas9	negative selection	2080562
48801923	48801946	X	+	26627737	HCT116	viability after 15 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.7867465159072871	[379]	[469,223,445]	7	hSpCas9	negative selection	2162872
48802772	48802795	X	-	26627737	HCT116	viability after 15 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.12412324112078921	[181]	[77,114,143]	1	hSpCas9	negative selection	2162873
48802945	48802968	X	+	26627737	HCT116	viability after 15 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.4130565926022792	[256]	[102,68,158]	-4	hSpCas9	negative selection	2162874
48803202	48803225	X	-	26627737	HCT116	viability after 15 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.8163415665729301	[118]	[99,174,83]	7	hSpCas9	negative selection	2162875
48805627	48805650	X	+	26627737	HCT116	viability after 15 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.5647982396352473	[707]	[803,426,597]	5	hSpCas9	negative selection	2162876
48806422	48806445	X	-	26627737	HCT116	viability after 15 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.6903014834584351	[397]	[383,328,394]	6	hSpCas9	negative selection	2162877
48801923	48801946	X	+	26627737	HCT116	viability after 18 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	1.23505148711964	[379]	[330,433,536]	8	hSpCas9	negative selection	2245187
48802772	48802795	X	-	26627737	HCT116	viability after 18 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.2572411152022347	[181]	[70,71,177]	2	hSpCas9	negative selection	2245188
48802945	48802968	X	+	26627737	HCT116	viability after 18 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-0.32717120376474207	[256]	[79,64,156]	-3	hSpCas9	negative selection	2245189
48803202	48803225	X	-	26627737	HCT116	viability after 18 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.43245324386297956	[118]	[36,144,44]	3	hSpCas9	negative selection	2245190
48805627	48805650	X	+	26627737	HCT116	viability after 18 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.5799599302565881	[707]	[492,398,656]	5	hSpCas9	negative selection	2245191
48806422	48806445	X	-	26627737	HCT116	viability after 18 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.7079662222327139	[397]	[267,306,370]	6	hSpCas9	negative selection	2245192
48802684	48802707	X	+	24336569	HL60	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.2901324407014527	[1176]	[2036]	-3	hSpCas9	negative selection	2269182
48802689	48802712	X	+	24336569	HL60	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	-0.15381494485358033	[367]	[699]	-1	hSpCas9	negative selection	2269183
48802697	48802720	X	-	24336569	HL60	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-0.7328920158688393	[793]	[1010]	-6	hSpCas9	negative selection	2269184
48802703	48802726	X	-	24336569	HL60	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	-1.4641838796350117	[102]	[78]	-8	hSpCas9	negative selection	2269185
48802715	48802738	X	-	24336569	HL60	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	-0.19493673937299916	[898]	[1661]	-2	hSpCas9	negative selection	2269186
48802721	48802744	X	+	24336569	HL60	viability	CAACCAGGCAGCGAAGAAGTAGG	HDAC6	ENSG00000094631	-0.25372603305774644	[1003]	[1781]	-2	hSpCas9	negative selection	2269187
48802761	48802784	X	-	24336569	HL60	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.7285649557270335	[1231]	[4319]	6	hSpCas9	negative selection	2269188
48802772	48802795	X	-	24336569	HL60	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.23488912379054067	[362]	[903]	2	hSpCas9	negative selection	2269189
48802910	48802933	X	-	24336569	HL60	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	2.3898416182966926	[65]	[731]	9	hSpCas9	negative selection	2269190
48802916	48802939	X	+	24336569	HL60	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	-0.7074767609925428	[908]	[1177]	-6	hSpCas9	negative selection	2269191
48802684	48802707	X	+	24336569	KBM7	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.5229125217741712	[1139]	[2163]	-4	hSpCas9	negative selection	2336359
48802689	48802712	X	+	24336569	KBM7	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	0.7123907242537506	[306]	[1371]	6	hSpCas9	negative selection	2336360
48802697	48802720	X	-	24336569	KBM7	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-0.04630767029529759	[565]	[1494]	0	hSpCas9	negative selection	2336361
48802703	48802726	X	-	24336569	KBM7	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	-2.0914353863236075	[49]	[31]	-8	hSpCas9	negative selection	2336362
48802715	48802738	X	-	24336569	KBM7	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	0.5037786411099467	[557]	[2157]	4	hSpCas9	negative selection	2336363
48802721	48802744	X	+	24336569	KBM7	viability	CAACCAGGCAGCGAAGAAGTAGG	HDAC6	ENSG00000094631	0.9637533326898422	[462]	[2462]	8	hSpCas9	negative selection	2336364
48802761	48802784	X	-	24336569	KBM7	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.0933807427049167	[920]	[2679]	0	hSpCas9	negative selection	2336365
48802772	48802795	X	-	24336569	KBM7	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.39655519352441576	[499]	[1035]	-3	hSpCas9	negative selection	2336366
48802910	48802933	X	-	24336569	KBM7	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.39473939776355205	[98]	[354]	3	hSpCas9	negative selection	2336367
48802916	48802939	X	+	24336569	KBM7	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.06276059293491576	[528]	[1506]	0	hSpCas9	negative selection	2336368
48801899	48801922	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTTTCTCAAACTCCGCCCTTGG	HDAC6	ENSG00000094631	-0.5456717634357701	[59,205]	[15,23]	-3	dCas9-VP64	positive selection	2439029
48801980	48802003	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCGGAGGCCGACCGAAGGCGG	HDAC6	ENSG00000094631	1.3119673787205763	[0,4]	[1,0]	5	dCas9-VP64	positive selection	2439030
48801930	48801953	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTACTCACCGCTCCACTCATTGG	HDAC6	ENSG00000094631	0.09959922744384908	[223,382]	[40,103]	0	dCas9-VP64	positive selection	2439031
48801899	48801922	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTTTCTCAAACTCCGCCCTTGG	HDAC6	ENSG00000094631	-0.7286642486838649	[130,110]	[31,15]	-7	dCas9-VP64	positive selection	2534284
48801980	48802003	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCGGAGGCCGACCGAAGGCGG	HDAC6	ENSG00000094631	-0.08190629913648872	[16,40]	[10,5]	0	dCas9-VP64	positive selection	2534285
48801930	48801953	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTACTCACCGCTCCACTCATTGG	HDAC6	ENSG00000094631	2.4768094884843275	[80,134]	[221,172]	9	dCas9-VP64	positive selection	2534286
48802910	48802933	X	-	27260157	DLD1	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.601057767190356	[]	[]	8	hSpCas9	negative selection	2577600
48802703	48802726	X	-	27260157	DLD1	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	0.372499294715748	[]	[]	4	hSpCas9	negative selection	2579973
48805498	48805521	X	-	27260157	DLD1	viability	GAAAGGACACGCAGCGATCTAGG	HDAC6	ENSG00000094631	0.424526213416205	[]	[]	7	hSpCas9	negative selection	2580941
48805627	48805650	X	+	27260157	DLD1	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.383535080361196	[]	[]	4	hSpCas9	negative selection	2582068
48802909	48802932	X	-	27260157	DLD1	viability	TCTTTACCTCCGCTAGATTGGGG	HDAC6	ENSG00000094631	0.382875445075197	[]	[]	4	hSpCas9	negative selection	2585754
48802761	48802784	X	-	27260157	DLD1	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.64163061000792	[]	[]	8	hSpCas9	negative selection	2587354
48802916	48802939	X	+	27260157	DLD1	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.593325360460318	[]	[]	8	hSpCas9	negative selection	2605469
48802689	48802712	X	+	27260157	DLD1	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	0.921061328968451	[]	[]	9	hSpCas9	negative selection	2606019
48802945	48802968	X	+	27260157	DLD1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.93079520006089	[]	[]	9	hSpCas9	negative selection	2611715
48802684	48802707	X	+	27260157	DLD1	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	0.0088823851611233	[]	[]	0	hSpCas9	negative selection	2612051
48805486	48805509	X	-	27260157	DLD1	viability	AGCGATCTAGGAGGCCCTCCTGG	HDAC6	ENSG00000094631	0.624567796912494	[]	[]	8	hSpCas9	negative selection	2612805
48802715	48802738	X	-	27260157	DLD1	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	-1.6814618446394	[]	[]	-8	hSpCas9	negative selection	2613059
48805468	48805491	X	+	27260157	DLD1	viability	CATCAAGGAGCAACTGATCCAGG	HDAC6	ENSG00000094631	0.592174540527431	[]	[]	8	hSpCas9	negative selection	2613060
48806422	48806445	X	-	27260157	DLD1	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.972216163085117	[]	[]	9	hSpCas9	negative selection	2620083
48802772	48802795	X	-	27260157	DLD1	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	1.14223350497255	[]	[]	9	hSpCas9	negative selection	2621425
48802697	48802720	X	-	27260157	DLD1	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-0.662365362028715	[]	[]	-5	hSpCas9	negative selection	2622602
48805453	48805476	X	+	27260157	DLD1	viability	TGAGCGGCTCCATGCCATCAAGG	HDAC6	ENSG00000094631	0.400757069675	[]	[]	4	hSpCas9	negative selection	2645198
48802975	48802998	X	-	27260157	DLD1	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.00528770736927649	[]	[]	0	hSpCas9	negative selection	2646887
48802910	48802933	X	-	27260157	HT1080	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.588037023898859	[]	[]	5	hSpCas9	negative selection	2653730
48802703	48802726	X	-	27260157	HT1080	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	-0.634448532716883	[]	[]	-8	hSpCas9	negative selection	2656103
48805498	48805521	X	-	27260157	HT1080	viability	GAAAGGACACGCAGCGATCTAGG	HDAC6	ENSG00000094631	0.200510679488478	[]	[]	2	hSpCas9	negative selection	2657071
48805627	48805650	X	+	27260157	HT1080	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.20542920916125	[]	[]	2	hSpCas9	negative selection	2658198
48802909	48802932	X	-	27260157	HT1080	viability	TCTTTACCTCCGCTAGATTGGGG	HDAC6	ENSG00000094631	-1.14099995843561	[]	[]	-8	hSpCas9	negative selection	2661884
48802761	48802784	X	-	27260157	HT1080	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.690531977709499	[]	[]	6	hSpCas9	negative selection	2663484
48802916	48802939	X	+	27260157	HT1080	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.788220352272197	[]	[]	7	hSpCas9	negative selection	2681599
48802689	48802712	X	+	27260157	HT1080	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	1.03511094083424	[]	[]	8	hSpCas9	negative selection	2682149
48802945	48802968	X	+	27260157	HT1080	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.89980115547467	[]	[]	9	hSpCas9	negative selection	2687845
48802684	48802707	X	+	27260157	HT1080	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.419132864690288	[]	[]	-7	hSpCas9	negative selection	2688181
48805486	48805509	X	-	27260157	HT1080	viability	AGCGATCTAGGAGGCCCTCCTGG	HDAC6	ENSG00000094631	0.225695172160302	[]	[]	2	hSpCas9	negative selection	2688935
48802715	48802738	X	-	27260157	HT1080	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	-0.623485121591455	[]	[]	-8	hSpCas9	negative selection	2689189
48805468	48805491	X	+	27260157	HT1080	viability	CATCAAGGAGCAACTGATCCAGG	HDAC6	ENSG00000094631	1.02708898294115	[]	[]	8	hSpCas9	negative selection	2689190
48806422	48806445	X	-	27260157	HT1080	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.210976899875303	[]	[]	2	hSpCas9	negative selection	2696213
48802772	48802795	X	-	27260157	HT1080	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.761699544819727	[]	[]	6	hSpCas9	negative selection	2697555
48802697	48802720	X	-	27260157	HT1080	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-1.99482127776741	[]	[]	-9	hSpCas9	negative selection	2698732
48805453	48805476	X	+	27260157	HT1080	viability	TGAGCGGCTCCATGCCATCAAGG	HDAC6	ENSG00000094631	0.983470304496378	[]	[]	8	hSpCas9	negative selection	2721328
48802975	48802998	X	-	27260157	HT1080	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.82775794391259	[]	[]	-8	hSpCas9	negative selection	2723017
48802910	48802933	X	-	27260157	MKN45	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.942281919536309	[]	[]	8	hSpCas9	negative selection	2729860
48802703	48802726	X	-	27260157	MKN45	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	-0.427525750739109	[]	[]	-6	hSpCas9	negative selection	2732233
48805498	48805521	X	-	27260157	MKN45	viability	GAAAGGACACGCAGCGATCTAGG	HDAC6	ENSG00000094631	-0.66756586347237	[]	[]	-7	hSpCas9	negative selection	2733201
48805627	48805650	X	+	27260157	MKN45	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	-0.265203262512389	[]	[]	-1	hSpCas9	negative selection	2734328
48802909	48802932	X	-	27260157	MKN45	viability	TCTTTACCTCCGCTAGATTGGGG	HDAC6	ENSG00000094631	-1.15091967380098	[]	[]	-8	hSpCas9	negative selection	2738014
48802761	48802784	X	-	27260157	MKN45	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.550861992682532	[]	[]	7	hSpCas9	negative selection	2739614
48802916	48802939	X	+	27260157	MKN45	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.449074306419102	[]	[]	6	hSpCas9	negative selection	2757729
48802689	48802712	X	+	27260157	MKN45	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	0.927696860443045	[]	[]	8	hSpCas9	negative selection	2758279
48802945	48802968	X	+	27260157	MKN45	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.524277279959851	[]	[]	6	hSpCas9	negative selection	2763975
48802684	48802707	X	+	27260157	MKN45	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.359520328600678	[]	[]	-1	hSpCas9	negative selection	2764311
48805486	48805509	X	-	27260157	MKN45	viability	AGCGATCTAGGAGGCCCTCCTGG	HDAC6	ENSG00000094631	0.727887862714458	[]	[]	7	hSpCas9	negative selection	2765065
48802715	48802738	X	-	27260157	MKN45	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	-1.71632979298848	[]	[]	-9	hSpCas9	negative selection	2765319
48805468	48805491	X	+	27260157	MKN45	viability	CATCAAGGAGCAACTGATCCAGG	HDAC6	ENSG00000094631	1.1319787716381	[]	[]	8	hSpCas9	negative selection	2765320
48806422	48806445	X	-	27260157	MKN45	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.212646770966422	[]	[]	5	hSpCas9	negative selection	2772343
48802772	48802795	X	-	27260157	MKN45	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.846840102892621	[]	[]	8	hSpCas9	negative selection	2773685
48802697	48802720	X	-	27260157	MKN45	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-0.972301973831279	[]	[]	-7	hSpCas9	negative selection	2774862
48805453	48805476	X	+	27260157	MKN45	viability	TGAGCGGCTCCATGCCATCAAGG	HDAC6	ENSG00000094631	-0.533844130463256	[]	[]	-6	hSpCas9	negative selection	2797458
48802975	48802998	X	-	27260157	MKN45	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.0937273831263849	[]	[]	0	hSpCas9	negative selection	2799147
48802910	48802933	X	-	27260157	RKO	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.652657924687482	[]	[]	3	hSpCas9	negative selection	2805990
48802703	48802726	X	-	27260157	RKO	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	-0.0973268947837796	[]	[]	0	hSpCas9	negative selection	2808363
48805498	48805521	X	-	27260157	RKO	viability	GAAAGGACACGCAGCGATCTAGG	HDAC6	ENSG00000094631	0.855388750055133	[]	[]	8	hSpCas9	negative selection	2809331
48805627	48805650	X	+	27260157	RKO	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.208273852631513	[]	[]	1	hSpCas9	negative selection	2810458
48802909	48802932	X	-	27260157	RKO	viability	TCTTTACCTCCGCTAGATTGGGG	HDAC6	ENSG00000094631	0.507240754410581	[]	[]	2	hSpCas9	negative selection	2814144
48802761	48802784	X	-	27260157	RKO	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	0.951470715764813	[]	[]	8	hSpCas9	negative selection	2815744
48802916	48802939	X	+	27260157	RKO	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.943360658433506	[]	[]	8	hSpCas9	negative selection	2833859
48802689	48802712	X	+	27260157	RKO	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	1.23981034351037	[]	[]	9	hSpCas9	negative selection	2834409
48802945	48802968	X	+	27260157	RKO	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.44059143470322	[]	[]	9	hSpCas9	negative selection	2840105
48802684	48802707	X	+	27260157	RKO	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.761090944476107	[]	[]	-7	hSpCas9	negative selection	2840441
48805486	48805509	X	-	27260157	RKO	viability	AGCGATCTAGGAGGCCCTCCTGG	HDAC6	ENSG00000094631	0.888227215189302	[]	[]	8	hSpCas9	negative selection	2841195
48802715	48802738	X	-	27260157	RKO	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	-0.82603295672363	[]	[]	-7	hSpCas9	negative selection	2841449
48805468	48805491	X	+	27260157	RKO	viability	CATCAAGGAGCAACTGATCCAGG	HDAC6	ENSG00000094631	0.869773538272951	[]	[]	8	hSpCas9	negative selection	2841450
48806422	48806445	X	-	27260157	RKO	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.455139184940818	[]	[]	2	hSpCas9	negative selection	2848473
48802772	48802795	X	-	27260157	RKO	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.134304771312324	[]	[]	0	hSpCas9	negative selection	2849815
48802697	48802720	X	-	27260157	RKO	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-0.498191450739746	[]	[]	-6	hSpCas9	negative selection	2850992
48805453	48805476	X	+	27260157	RKO	viability	TGAGCGGCTCCATGCCATCAAGG	HDAC6	ENSG00000094631	0.748221548636724	[]	[]	8	hSpCas9	negative selection	2873588
48802975	48802998	X	-	27260157	RKO	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.45257253105543	[]	[]	-6	hSpCas9	negative selection	2875277
48802910	48802933	X	-	27260157	SF268	viability	TTCTTTACCTCCGCTAGATTGGG	HDAC6	ENSG00000094631	0.707708521887393	[]	[]	8	hSpCas9	negative selection	2882120
48802703	48802726	X	-	27260157	SF268	viability	GGTTGTGGTGGAATCCTGGCCGG	HDAC6	ENSG00000094631	0.517512310558646	[]	[]	8	hSpCas9	negative selection	2884493
48805498	48805521	X	-	27260157	SF268	viability	GAAAGGACACGCAGCGATCTAGG	HDAC6	ENSG00000094631	0.607391327285171	[]	[]	8	hSpCas9	negative selection	2885461
48805627	48805650	X	+	27260157	SF268	viability	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	-0.00815513976775568	[]	[]	0	hSpCas9	negative selection	2886588
48802909	48802932	X	-	27260157	SF268	viability	TCTTTACCTCCGCTAGATTGGGG	HDAC6	ENSG00000094631	1.00441725703124	[]	[]	9	hSpCas9	negative selection	2890274
48802761	48802784	X	-	27260157	SF268	viability	AAGTGACACTGGAGTCCTGAGGG	HDAC6	ENSG00000094631	1.33264282521087	[]	[]	9	hSpCas9	negative selection	2891874
48802916	48802939	X	+	27260157	SF268	viability	CTAGCGGAGGTAAAGAAGAAAGG	HDAC6	ENSG00000094631	0.705857784358913	[]	[]	8	hSpCas9	negative selection	2909989
48802689	48802712	X	+	27260157	SF268	viability	AACTATGACCTCAACCGGCCAGG	HDAC6	ENSG00000094631	0.930927416076695	[]	[]	9	hSpCas9	negative selection	2910539
48802945	48802968	X	+	27260157	SF268	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.35187534488034	[]	[]	9	hSpCas9	negative selection	2916235
48802684	48802707	X	+	27260157	SF268	viability	TCCTCAACTATGACCTCAACCGG	HDAC6	ENSG00000094631	-0.166136738038317	[]	[]	-1	hSpCas9	negative selection	2916571
48805486	48805509	X	-	27260157	SF268	viability	AGCGATCTAGGAGGCCCTCCTGG	HDAC6	ENSG00000094631	-0.00990907352016857	[]	[]	0	hSpCas9	negative selection	2917325
48802715	48802738	X	-	27260157	SF268	viability	TCTTCGCTGCCTGGTTGTGGTGG	HDAC6	ENSG00000094631	0.55933878168223	[]	[]	8	hSpCas9	negative selection	2917579
48805468	48805491	X	+	27260157	SF268	viability	CATCAAGGAGCAACTGATCCAGG	HDAC6	ENSG00000094631	0.762701054083045	[]	[]	8	hSpCas9	negative selection	2917580
48806422	48806445	X	-	27260157	SF268	viability	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.269826499619647	[]	[]	4	hSpCas9	negative selection	2924603
48802772	48802795	X	-	27260157	SF268	viability	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.739100399856783	[]	[]	8	hSpCas9	negative selection	2925945
48802697	48802720	X	-	27260157	SF268	viability	GGTGGAATCCTGGCCGGTTGAGG	HDAC6	ENSG00000094631	-1.09380969372949	[]	[]	-7	hSpCas9	negative selection	2927122
48805453	48805476	X	+	27260157	SF268	viability	TGAGCGGCTCCATGCCATCAAGG	HDAC6	ENSG00000094631	0.961570542318824	[]	[]	9	hSpCas9	negative selection	2949718
48802975	48802998	X	-	27260157	SF268	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.00381518795054611	[]	[]	0	hSpCas9	negative selection	2951407
48808073	48808096	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	0.48510438997354693	[3,3]	[4,4]	8	hSpCas9	positive selection	2992884
48802898	48802921	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	0.3029302267106756	[2,2]	[3,2]	6	hSpCas9	positive selection	2992885
48817315	48817338	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	0.16062824344120932	[4,4]	[3,4]	3	hSpCas9	positive selection	2992886
48808285	48808308	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	-0.7558382348431998	[3,3]	[2,0]	-8	hSpCas9	positive selection	2992887
48808073	48808096	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	-0.11412452137957807	[3,3]	[1,1]	-2	hSpCas9	positive selection	3060742
48802898	48802921	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	-0.6982337553128575	[2,2]	[1,0]	-8	hSpCas9	positive selection	3060743
48817315	48817338	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	0.17779749256114374	[4,4]	[3,3]	3	hSpCas9	positive selection	3060744
48808285	48808308	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	0.04924389101365169	[3,3]	[3,1]	0	hSpCas9	positive selection	3060745
48815605	48815628		+	24336571	A375	resistance to PLX after 7 days	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	0.2711894729556743	[3,4]	[4,5]	7	hSpCas9	positive selection	3118628
48815982	48816005		+	24336571	A375	resistance to PLX after 7 days	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.21244038172623647	[22,20]	[19,18]	-6	hSpCas9	positive selection	3118630
48815982	48816005		-	24336571	A375	resistance to PLX after 7 days	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.08760367870019409	[20,17]	[19,16]	-3	hSpCas9	positive selection	3118631
48815616	48815639		-	24336571	A375	resistance to PLX after 7 days	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	0.5008922102322753	[3,3]	[4,5]	9	hSpCas9	positive selection	3118632
48815605	48815628		+	24336571	A375	resistance to PLX after 14 days	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	2.0333331045049343	[5,2]	[7,9]	9	hSpCas9	positive selection	3176421
48815982	48816005		+	24336571	A375	resistance to PLX after 14 days	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	2.393191089768049	[26,15]	[49,56]	9	hSpCas9	positive selection	3176423
48815982	48816005		-	24336571	A375	resistance to PLX after 14 days	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.14440745965740637	[17,13]	[6,5]	-1	hSpCas9	positive selection	3176424
48815616	48815639		-	24336571	A375	resistance to PLX after 14 days	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	1.0144629179504312	[2,6]	[4,3]	7	hSpCas9	positive selection	3176425
48815605	48815628		+	24336571	A375	viability after 7 days	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	-0.47089119702855564	[6]	[3,4]	-6	hSpCas9	negative selection	3234214
48815982	48816005		+	24336571	A375	viability after 7 days	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.006516741758491373	[23]	[22,20]	0	hSpCas9	negative selection	3234216
48815982	48816005		-	24336571	A375	viability after 7 days	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.39373834520586065	[14]	[20,17]	6	hSpCas9	negative selection	3234217
48815616	48815639		-	24336571	A375	viability after 7 days	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	-0.2966045442406928	[4]	[3,3]	-4	hSpCas9	negative selection	3234218
48815605	48815628		+	24336571	A375	viability after 14 days	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	-0.46565895096101784	[6]	[5,2]	-5	hSpCas9	negative selection	3292007
48815982	48816005		+	24336571	A375	viability after 14 days	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.04289836217823595	[23]	[26,15]	0	hSpCas9	negative selection	3292009
48815982	48816005		-	24336571	A375	viability after 14 days	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.17558640593828906	[14]	[17,13]	2	hSpCas9	negative selection	3292010
48815616	48815639		-	24336571	A375	viability after 14 days	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	0.006837181450763508	[4]	[2,6]	0	hSpCas9	negative selection	3292011
48816159	48816182	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	3.0894981508391024	[13,21]	[0,0]	8	hSpCas9	positive selection	3353123
48802975	48802998	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-1.402448207610028	[394,413]	[0,0]	-8	hSpCas9	positive selection	3353124
48815982	48816005	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.2215293073167529	[160,195]	[0,0]	-1	hSpCas9	positive selection	3353125
48802911	48802934	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	-1.404451886326152	[404,404]	[0,0]	-8	hSpCas9	positive selection	3372316
48816168	48816191	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	1.0478728458168853	[73,73]	[0,0]	5	hSpCas9	positive selection	3372317
48815982	48816005	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.7539010439774191	[257,257]	[0,0]	-5	hSpCas9	positive selection	3372318
48808072	48808095	X	+	26780180	HT29	viability (Avana library 4 designs)	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	1.61708005044663	[]	[]	6	hSpCas9	negative selection	3430145
48802898	48802921	X	-	26780180	HT29	viability (Avana library 4 designs)	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	1.12087735560978	[]	[]	4	hSpCas9	negative selection	3430146
48817314	48817337	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	0.164388797340481	[]	[]	0	hSpCas9	negative selection	3430147
48808285	48808308	X	-	26780180	HT29	viability (Avana library 4 designs)	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	0.113903540969324	[]	[]	0	hSpCas9	negative selection	3430148
48808072	48808095	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	-0.656882435073512	[]	[]	-1	hSpCas9	negative selection	3515161
48802898	48802921	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	2.89234519577434	[]	[]	4	hSpCas9	negative selection	3515162
48808285	48808308	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	5.99548106612049	[]	[]	9	hSpCas9	negative selection	3515163
48817314	48817337	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	-1.6306498225642	[]	[]	-2	hSpCas9	negative selection	3515164
48808268	48808291	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATTGGGATGTGCACCACGG	HDAC6	ENSG00000094631	0.6342407049197	[]	[]	0	hSpCas9	negative selection	3515165
48808087	48808110	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCGGGCTGCCACAGCCACGTGG	HDAC6	ENSG00000094631	6.64616362437007	[]	[]	9	hSpCas9	negative selection	3515166
48808072	48808095	X	+	26780180	A375	viability (Avana lentiGuide)	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	-4.68191508651067	[]	[]	-7	hSpCas9	negative selection	3623820
48802898	48802921	X	-	26780180	A375	viability (Avana lentiGuide)	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	-5.17241851382431	[]	[]	-8	hSpCas9	negative selection	3623821
48808285	48808308	X	-	26780180	A375	viability (Avana lentiGuide)	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	-1.78654626102312	[]	[]	-3	hSpCas9	negative selection	3623822
48817314	48817337	X	+	26780180	A375	viability (Avana lentiGuide)	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	-6.98193362281842	[]	[]	-9	hSpCas9	negative selection	3623823
48808268	48808291	X	+	26780180	A375	viability (Avana lentiGuide)	GTAGATTGGGATGTGCACCACGG	HDAC6	ENSG00000094631	1.20877705477069	[]	[]	1	hSpCas9	negative selection	3623824
48808087	48808110	X	-	26780180	A375	viability (Avana lentiGuide)	AGCGGGCTGCCACAGCCACGTGG	HDAC6	ENSG00000094631	-1.7865994349392	[]	[]	-3	hSpCas9	negative selection	3623825
48808072	48808095	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	0.032195212151009116	[5]	[5,4]	0	hSpCas9	positive selection	3732479
48802898	48802921	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	0.14269945605386852	[4]	[4,4]	4	hSpCas9	positive selection	3732480
48808285	48808308	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	0.2643598009051367	[4]	[6,5]	7	hSpCas9	positive selection	3732481
48817314	48817337	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	-0.10288150926269367	[4]	[3,4]	-2	hSpCas9	positive selection	3732482
48808268	48808291	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATTGGGATGTGCACCACGG	HDAC6	ENSG00000094631	-0.12197481349318805	[5]	[4,4]	-2	hSpCas9	positive selection	3732483
48808087	48808110	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCGGGCTGCCACAGCCACGTGG	HDAC6	ENSG00000094631	0.4510010861394259	[4]	[6,5]	9	hSpCas9	positive selection	3732484
48808072	48808095	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATTGCATGTTCAACCACGTGG	HDAC6	ENSG00000094631	0.21113015755571943	[5]	[5,4]	5	hSpCas9	positive selection	3841086
48802898	48802921	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTAGATTGGGGATAGAGCGGGG	HDAC6	ENSG00000094631	-0.08874206325585965	[4]	[5,0]	-1	hSpCas9	positive selection	3841087
48808285	48808308	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAACTGTGTTCCTTGACCGTGG	HDAC6	ENSG00000094631	0.2273140790338127	[5]	[5,5]	6	hSpCas9	positive selection	3841088
48817314	48817337	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTTCCCAGGTTCTGAATGG	HDAC6	ENSG00000094631	0.2644104542618487	[5]	[5,5]	7	hSpCas9	positive selection	3841089
48808268	48808291	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATTGGGATGTGCACCACGG	HDAC6	ENSG00000094631	0.01619899842417577	[5]	[5,3]	0	hSpCas9	positive selection	3841090
48808087	48808110	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCGGGCTGCCACAGCCACGTGG	HDAC6	ENSG00000094631	0.13095711932642023	[5]	[4,5]	3	hSpCas9	positive selection	3841091
48816159	48816182	X	-	26780180	A375	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.96734513687202	[]	[]	4	hSpCas9	negative selection	3947156
48815982	48816005	X	+	26780180	A375	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	2.02924364430378	[]	[]	9	hSpCas9	negative selection	3947157
48815982	48816005	X	-	26780180	A375	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.94542438923045	[]	[]	4	hSpCas9	negative selection	3947158
48802911	48802934	X	-	26780180	A375	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	-0.0656466562938658	[]	[]	-2	hSpCas9	negative selection	3947159
48816168	48816191	X	+	26780180	A375	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	1.05154994000171	[]	[]	5	hSpCas9	negative selection	3947160
48802975	48802998	X	-	26780180	A375	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.446995446590039	[]	[]	1	hSpCas9	negative selection	3947161
48816159	48816182	X	-	26780180	HT29	viability (GeCKOv2 library)	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	1.07492922455673	[]	[]	5	hSpCas9	negative selection	4055122
48815982	48816005	X	+	26780180	HT29	viability (GeCKOv2 library)	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	2.49928688906552	[]	[]	9	hSpCas9	negative selection	4055123
48815982	48816005	X	-	26780180	HT29	viability (GeCKOv2 library)	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	1.28029197262863	[]	[]	6	hSpCas9	negative selection	4055124
48802911	48802934	X	-	26780180	HT29	viability (GeCKOv2 library)	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.0239786777877148	[]	[]	0	hSpCas9	negative selection	4055125
48816168	48816191	X	+	26780180	HT29	viability (GeCKOv2 library)	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	1.51420125517551	[]	[]	7	hSpCas9	negative selection	4055126
48802975	48802998	X	-	26780180	HT29	viability (GeCKOv2 library)	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.219258432938176	[]	[]	0	hSpCas9	negative selection	4055127
48815605	48815628	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	0.12257457012248228	[3]	[1,3]	3	hSpCas9	positive selection	4142065
48815982	48816005	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.3891838212780987	[4]	[1,5]	8	hSpCas9	positive selection	4142067
48815982	48816005	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.03473068492178008	[4]	[2,2]	-1	hSpCas9	positive selection	4142068
48815616	48815639	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	-0.05397969903389571	[2]	[1,1]	-1	hSpCas9	positive selection	4142069
48815605	48815628	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCCCTTGAGCCCTTCTGGGAGG	HDAC6	ENSG00000094631	1.153725766492264	[0]	[3,0,0,0]	8	hSpCas9	positive selection	4206087
48815982	48816005	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.5995520112045575	[4]	[1,0,0,4]	4	hSpCas9	positive selection	4206089
48815982	48816005	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.10855999490999943	[4]	[4,0,1,0]	-1	hSpCas9	positive selection	4206090
48815616	48815639	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCACAAGAACCTCCCAGAAGG	HDAC6	ENSG00000094631	0.2538646328218468	[2]	[3,2,0,0]	2	hSpCas9	positive selection	4206091
48816159	48816182	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.4065964757595153	[1]	[1,0]	-7	hSpCas9	positive selection	4274697
48802975	48802998	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.2307387915204533	[4]	[4,4]	4	hSpCas9	positive selection	4274698
48815982	48816005	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.3470997907659273	[2]	[2,0]	-6	hSpCas9	positive selection	4274699
48802911	48802934	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.5378228325332666	[3]	[4,4]	9	hSpCas9	positive selection	4338958
48816168	48816191	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.985688981997775	[2]	[3,4]	9	hSpCas9	positive selection	4338959
48815982	48816005	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.0074277855178704055	[3]	[2,2]	0	hSpCas9	positive selection	4338960
48802904	48802926	X	+	27760321	OCIAML3	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.2389962899425706	[674,601]	[548,639]	3	hSpCas9	negative selection	4406419
48815983	48816005	X	+	27760321	OCIAML3	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.4640372175108775	[571,528]	[576,615]	5	hSpCas9	negative selection	4406420
48816158	48816180	X	-	27760321	OCIAML3	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	0.24581399901104173	[561,540]	[441,603]	3	hSpCas9	negative selection	4406421
48805495	48805517	X	-	27760321	OCIAML3	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.5042754613477318	[682,524]	[549,814]	6	hSpCas9	negative selection	4406422
48814461	48814483	X	-	27760321	OCIAML3	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.20564047911843975	[955,763]	[652,924]	2	hSpCas9	negative selection	4406423
48802904	48802926	X	+	27760321	OCIAML2	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.7387209956150724	[674,601]	[757,995]	8	hSpCas9	negative selection	4489882
48815983	48816005	X	+	27760321	OCIAML2	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.046229739167891803	[571,528]	[404,465]	0	hSpCas9	negative selection	4489883
48816158	48816180	X	-	27760321	OCIAML2	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	0.3922510456731678	[561,540]	[548,635]	5	hSpCas9	negative selection	4489884
48805495	48805517	X	-	27760321	OCIAML2	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.3291102926489114	[682,524]	[490,764]	4	hSpCas9	negative selection	4489885
48814461	48814483	X	-	27760321	OCIAML2	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.5339031642975228	[955,763]	[949,1068]	7	hSpCas9	negative selection	4489886
48802904	48802926	X	+	27760321	MV411	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	1.0922747621313154	[674,601]	[1002,737]	7	hSpCas9	negative selection	4573345
48815983	48816005	X	+	27760321	MV411	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.5199184477668803	[571,528]	[438,643]	4	hSpCas9	negative selection	4573346
48816158	48816180	X	-	27760321	MV411	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	0.9941489431674713	[561,540]	[933,413]	7	hSpCas9	negative selection	4573347
48805495	48805517	X	-	27760321	MV411	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.20803762254075714	[682,524]	[426,501]	1	hSpCas9	negative selection	4573348
48814461	48814483	X	-	27760321	MV411	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.7643463842105013	[955,763]	[853,1114]	5	hSpCas9	negative selection	4573349
48802904	48802926	X	+	27760321	HL60	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.08174428711846693	[674,601]	[441,666]	1	hSpCas9	negative selection	4656808
48815983	48816005	X	+	27760321	HL60	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-1.1067863219917378	[571,528]	[235,179]	-8	hSpCas9	negative selection	4656809
48816158	48816180	X	-	27760321	HL60	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	0.06864876591198138	[561,540]	[498,445]	0	hSpCas9	negative selection	4656810
48805495	48805517	X	-	27760321	HL60	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	-0.4222501890072477	[682,524]	[363,366]	-5	hSpCas9	negative selection	4656811
48814461	48814483	X	-	27760321	HL60	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	-0.336763719971623	[955,763]	[618,482]	-4	hSpCas9	negative selection	4656812
48802904	48802926	X	+	27760321	HT1080	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	1.046343523281188	[601,469]	[556,313]	5	hSpCas9	negative selection	4740271
48815983	48816005	X	+	27760321	HT1080	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.7724087294439674	[528,412]	[288,354]	4	hSpCas9	negative selection	4740272
48816158	48816180	X	-	27760321	HT1080	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	2.6206914045150165	[540,421]	[1278,1070]	9	hSpCas9	negative selection	4740273
48805495	48805517	X	-	27760321	HT1080	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.3344284133799931	[524,409]	[283,180]	1	hSpCas9	negative selection	4740274
48814461	48814483	X	-	27760321	HT1080	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	-1.5154389906208228	[763,595]	[78,111]	-5	hSpCas9	negative selection	4740275
48802904	48802926	X	+	27760321	HT29	viability after 7 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	-0.12119261697869077	[601,469]	[746,721,452]	-2	hSpCas9	negative selection	4823734
48815983	48816005	X	+	27760321	HT29	viability after 7 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.3757705186058575	[528,412]	[797,554,997]	6	hSpCas9	negative selection	4823735
48816158	48816180	X	-	27760321	HT29	viability after 7 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.29929628882357756	[540,421]	[550,641,327]	-4	hSpCas9	negative selection	4823736
48805495	48805517	X	-	27760321	HT29	viability after 7 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.09467012366540112	[524,409]	[822,533,594]	1	hSpCas9	negative selection	4823737
48814461	48814483	X	-	27760321	HT29	viability after 7 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.21920169776478715	[763,595]	[1066,919,1069]	3	hSpCas9	negative selection	4823738
48802904	48802926	X	+	27760321	HT29	viability after 25 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.2581049432032164	[601,469]	[885,722,559]	2	hSpCas9	negative selection	4907197
48815983	48816005	X	+	27760321	HT29	viability after 25 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.11091427458527353	[528,412]	[719,374,645]	1	hSpCas9	negative selection	4907198
48816158	48816180	X	-	27760321	HT29	viability after 25 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.7271043560120957	[540,421]	[248,342,418]	-6	hSpCas9	negative selection	4907199
48805495	48805517	X	-	27760321	HT29	viability after 25 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.2329388699462458	[524,409]	[574,554,770]	2	hSpCas9	negative selection	4907200
48814461	48814483	X	-	27760321	HT29	viability after 25 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.23628759582546188	[763,595]	[814,1012,923]	2	hSpCas9	negative selection	4907201
48802904	48802926	X	+	27760321	HT29	viability after 22 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.08182804670571397	[601,469]	[812,512,636]	0	hSpCas9	negative selection	4990660
48815983	48816005	X	+	27760321	HT29	viability after 22 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.26198031299088437	[528,412]	[924,417,607]	2	hSpCas9	negative selection	4990661
48816158	48816180	X	-	27760321	HT29	viability after 22 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.8135428557515845	[540,421]	[257,344,348]	-6	hSpCas9	negative selection	4990662
48805495	48805517	X	-	27760321	HT29	viability after 22 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.0006778902297804312	[524,409]	[640,484,492]	0	hSpCas9	negative selection	4990663
48814461	48814483	X	-	27760321	HT29	viability after 22 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.5597881716202614	[763,595]	[1341,1097,1029]	6	hSpCas9	negative selection	4990664
48802904	48802926	X	+	27760321	HT29	viability after 19 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	-0.4287408332306568	[601,469]	[630,556,205]	-4	hSpCas9	negative selection	5074123
48815983	48816005	X	+	27760321	HT29	viability after 19 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.41532096126443324	[528,412]	[911,465,793]	4	hSpCas9	negative selection	5074124
48816158	48816180	X	-	27760321	HT29	viability after 19 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.8929459952982235	[540,421]	[508,168,235]	-6	hSpCas9	negative selection	5074125
48805495	48805517	X	-	27760321	HT29	viability after 19 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	-0.22778329704273673	[524,409]	[633,322,431]	-2	hSpCas9	negative selection	5074126
48814461	48814483	X	-	27760321	HT29	viability after 19 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.06492552295285936	[763,595]	[873,779,792]	0	hSpCas9	negative selection	5074127
48802904	48802926	X	+	27760321	HT29	viability after 16 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.059978741616896425	[601,469]	[799,619,471]	0	hSpCas9	negative selection	5157586
48815983	48816005	X	+	27760321	HT29	viability after 16 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.11283102114437943	[528,412]	[691,342,449]	-1	hSpCas9	negative selection	5157587
48816158	48816180	X	-	27760321	HT29	viability after 16 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.4279209510900351	[540,421]	[387,324,488]	-4	hSpCas9	negative selection	5157588
48805495	48805517	X	-	27760321	HT29	viability after 16 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.7535042242233688	[524,409]	[754,1047,825]	8	hSpCas9	negative selection	5157589
48814461	48814483	X	-	27760321	HT29	viability after 16 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.0692425999755184	[763,595]	[770,790,829]	0	hSpCas9	negative selection	5157590
48802904	48802926	X	+	27760321	HT29	viability after 13 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	-0.19071471148791447	[601,469]	[596,504,532]	-2	hSpCas9	negative selection	5241049
48815983	48816005	X	+	27760321	HT29	viability after 13 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.4522487858117356	[528,412]	[959,957,348]	6	hSpCas9	negative selection	5241050
48816158	48816180	X	-	27760321	HT29	viability after 13 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.06439223372863029	[540,421]	[553,472,572]	-1	hSpCas9	negative selection	5241051
48805495	48805517	X	-	27760321	HT29	viability after 13 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.36756241863377603	[524,409]	[819,632,648]	4	hSpCas9	negative selection	5241052
48814461	48814483	X	-	27760321	HT29	viability after 13 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.2541326874837132	[763,595]	[690,1006,1113]	3	hSpCas9	negative selection	5241053
48802904	48802926	X	+	27760321	HT29	viability after 10 days	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	-0.09991223259672266	[601,469]	[467,748,658]	-1	hSpCas9	negative selection	5324512
48815983	48816005	X	+	27760321	HT29	viability after 10 days	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.3162089614080758	[528,412]	[789,636,765]	4	hSpCas9	negative selection	5324513
48816158	48816180	X	-	27760321	HT29	viability after 10 days	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	-0.20661189091293988	[540,421]	[600,449,509]	-3	hSpCas9	negative selection	5324514
48805495	48805517	X	-	27760321	HT29	viability after 10 days	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	0.2856811089957222	[524,409]	[987,456,682]	4	hSpCas9	negative selection	5324515
48814461	48814483	X	-	27760321	HT29	viability after 10 days	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	-0.045368440594403814	[763,595]	[555,881,1026]	0	hSpCas9	negative selection	5324516
48802904	48802926	X	+	27760321	MOLM13	viability	TCTATCCCCAATCTAGCGGAGG	HDAC6	ENSG00000094631	0.7156471198863144	[674,601]	[398,753]	5	hSpCas9	negative selection	5407975
48815983	48816005	X	+	27760321	MOLM13	viability	CAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	1.150880229013883	[571,528]	[706,674]	7	hSpCas9	negative selection	5407976
48816158	48816180	X	-	27760321	MOLM13	viability	ATGATCCGCAAGATGCGCTGGG	HDAC6	ENSG00000094631	0.49119472920710305	[561,540]	[328,530]	3	hSpCas9	negative selection	5407977
48805495	48805517	X	-	27760321	MOLM13	viability	GGACACGCAGCGATCTAGGAGG	HDAC6	ENSG00000094631	1.242699244984456	[682,524]	[1137,512]	8	hSpCas9	negative selection	5407978
48814461	48814483	X	-	27760321	MOLM13	viability	GAACCTACCCTGCTCGTAGCGG	HDAC6	ENSG00000094631	0.7489072174704231	[955,763]	[1057,599]	5	hSpCas9	negative selection	5407979
48802080	48802103	X	+	27661255	K562	viability	GGGCAGTCCCCTGAGGAGCGGGG	HDAC6	ENSG00000094631	-0.17656634809998661	[784,826]	[634,512]	-5	dCas9-KRAB	negative selection	5484278
48802109	48802132	X	+	27661255	K562	viability	GAAACGCTAGGGGCGGGATCTGG	HDAC6	ENSG00000094631	-0.4577126478942948	[523,551]	[364,267]	-7	dCas9-KRAB	negative selection	5484279
48802218	48802241	X	+	27661255	K562	viability	GGCCGGCTGAGTGAAAGGGTGGG	HDAC6	ENSG00000094631	0.129227227563057	[543,602]	[572,437]	4	dCas9-KRAB	negative selection	5484280
48802496	48802519	X	+	27661255	K562	viability	GGAGGGAGAAGGCCTGAGAGAGG	HDAC6	ENSG00000094631	-1.2489783618901746	[975,1349]	[474,314]	-8	dCas9-KRAB	negative selection	5484281
48816159	48816182	X	-	27260156	BXPC3	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.06550154183935164	[132]	[97,164,91,182]	-1	hSpCas9	negative selection	5547157
48802975	48802998	X	-	27260156	BXPC3	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.13074246981936577	[1948]	[1865,2132,2135,2900]	3	hSpCas9	negative selection	5547158
48815982	48816005	X	+	27260156	BXPC3	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.14689983528362488	[449]	[410,526,525,642]	3	hSpCas9	negative selection	5547159
48802911	48802934	X	-	27260156	BXPC3	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3258793705526759	[906]	[934,1103,1382,1384]	7	hSpCas9	negative selection	5611418
48816168	48816191	X	+	27260156	BXPC3	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.34254428710558893	[247]	[284,264,308,480]	7	hSpCas9	negative selection	5611419
48815982	48816005	X	-	27260156	BXPC3	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.019969876167559297	[739]	[707,772,672,1013]	0	hSpCas9	negative selection	5611420
48816159	48816182	X	-	27260156	A673	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.2648504959610807	[132]	[162,114,144,110]	-6	hSpCas9	negative selection	5668408
48802975	48802998	X	-	27260156	A673	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.013211438916281182	[1948]	[2573,2082,2540,2093]	0	hSpCas9	negative selection	5668409
48815982	48816005	X	+	27260156	A673	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.1660073112294415	[449]	[655,463,650,664]	4	hSpCas9	negative selection	5668410
48802911	48802934	X	-	27260156	A673	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.40874909079078914	[906]	[1651,1416,1263,1474]	8	hSpCas9	negative selection	5732669
48816168	48816191	X	+	27260156	A673	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.1965368245524114	[247]	[263,198,294,283]	-5	hSpCas9	negative selection	5732670
48815982	48816005	X	-	27260156	A673	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.04357529508279079	[739]	[790,923,938,996]	1	hSpCas9	negative selection	5732671
48816159	48816182	X	-	27260156	A375	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.1806178590394485	[132]	[279,144,98,175]	2	hSpCas9	negative selection	5789659
48802975	48802998	X	-	27260156	A375	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.010601894776189447	[1948]	[2359,2915,2282,1756]	0	hSpCas9	negative selection	5789660
48815982	48816005	X	+	27260156	A375	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.22234629050499843	[449]	[557,730,579,598]	3	hSpCas9	negative selection	5789661
48802911	48802934	X	-	27260156	A375	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.7789113540826229	[906]	[1550,2120,2045,1610]	9	hSpCas9	negative selection	5853920
48816168	48816191	X	+	27260156	A375	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.025117597642410505	[247]	[266,298,321,254]	0	hSpCas9	negative selection	5853921
48815982	48816005	X	-	27260156	A375	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.07973199871826941	[739]	[867,866,829,721]	-1	hSpCas9	negative selection	5853922
48816159	48816182	X	-	27260156	COLO741	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.2639077050093612	[132]	[108,176,135]	-5	hSpCas9	negative selection	5910910
48802975	48802998	X	-	27260156	COLO741	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.0017653382295370612	[1948]	[3123,2473,1968]	0	hSpCas9	negative selection	5910911
48815982	48816005	X	+	27260156	COLO741	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.22083200581204748	[449]	[663,726,620]	5	hSpCas9	negative selection	5910912
48802911	48802934	X	-	27260156	COLO741	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3298366022306911	[906]	[1646,1540,1212]	6	hSpCas9	negative selection	5975171
48816168	48816191	X	+	27260156	COLO741	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.24987698648729417	[247]	[172,377,241]	-5	hSpCas9	negative selection	5975172
48815982	48816005	X	-	27260156	COLO741	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.004161325828251461	[739]	[1047,870,932]	0	hSpCas9	negative selection	5975173
48816159	48816182	X	-	27260156	CAL120	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.6313141938599232	[132]	[334,311,135]	8	hSpCas9	negative selection	6032161
48802975	48802998	X	-	27260156	CAL120	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.15746924207368496	[1948]	[2416,2014,2127]	-2	hSpCas9	negative selection	6032162
48815982	48816005	X	+	27260156	CAL120	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.032511313371233586	[449]	[757,483,433]	0	hSpCas9	negative selection	6032163
48802911	48802934	X	-	27260156	CAL120	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.32789609565148825	[906]	[997,1411,1769]	5	hSpCas9	negative selection	6096422
48816168	48816191	X	+	27260156	CAL120	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.086279269669859	[247]	[455,270,275]	1	hSpCas9	negative selection	6096423
48815982	48816005	X	-	27260156	CAL120	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.414406678516537	[739]	[770,478,831]	-5	hSpCas9	negative selection	6096424
48816159	48816182	X	-	27260156	CADOES1	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.014915077374802577	[132]	[125,163,71,127]	0	hSpCas9	negative selection	6153412
48802975	48802998	X	-	27260156	CADOES1	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.3825317563811115	[1948]	[1266,1295,1532,1468]	-6	hSpCas9	negative selection	6153413
48815982	48816005	X	+	27260156	CADOES1	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.4568909478417314	[449]	[561,487,562,688]	7	hSpCas9	negative selection	6153414
48802911	48802934	X	-	27260156	CADOES1	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.31619477856683886	[906]	[942,1106,1112,1037]	5	hSpCas9	negative selection	6217673
48816168	48816191	X	+	27260156	CADOES1	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.06904340770657535	[247]	[278,213,149,236]	-1	hSpCas9	negative selection	6217674
48815982	48816005	X	-	27260156	CADOES1	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.29709999914014695	[739]	[583,568,541,544]	-5	hSpCas9	negative selection	6217675
48816159	48816182	X	-	27260156	EWS502	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.013282892501958132	[132]	[85,91,181,211]	0	hSpCas9	negative selection	6274663
48802975	48802998	X	-	27260156	EWS502	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.21422850769487112	[1948]	[1714,1558,1916,1950]	-4	hSpCas9	negative selection	6274664
48815982	48816005	X	+	27260156	EWS502	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.051556587537901946	[449]	[463,546,503,457]	0	hSpCas9	negative selection	6274665
48802911	48802934	X	-	27260156	EWS502	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.5269166700925276	[906]	[1141,1218,1565,1662]	8	hSpCas9	negative selection	6338924
48816168	48816191	X	+	27260156	EWS502	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.03495556486015905	[247]	[145,331,308,247]	0	hSpCas9	negative selection	6338925
48815982	48816005	X	-	27260156	EWS502	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.21890794956959503	[739]	[651,746,504,792]	-4	hSpCas9	negative selection	6338926
48816159	48816182	X	-	27260156	EW8	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.032495821380144285	[132]	[122,154,30,126]	0	hSpCas9	negative selection	6395914
48802975	48802998	X	-	27260156	EW8	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.5177345609488619	[1948]	[1145,1224,991,1070]	-7	hSpCas9	negative selection	6395915
48815982	48816005	X	+	27260156	EW8	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.009847584056891748	[449]	[417,370,278,399]	0	hSpCas9	negative selection	6395916
48802911	48802934	X	-	27260156	EW8	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.35187597143213045	[906]	[808,1064,841,1035]	6	hSpCas9	negative selection	6460175
48816168	48816191	X	+	27260156	EW8	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.29943658317533517	[247]	[301,241,203,253]	5	hSpCas9	negative selection	6460176
48815982	48816005	X	-	27260156	EW8	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.5211212274113632	[739]	[487,449,408,332]	-7	hSpCas9	negative selection	6460177
48816159	48816182	X	-	27260156	CORL105	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.4279847440585498	[132]	[168,72,111,110]	-7	hSpCas9	negative selection	6517165
48802975	48802998	X	-	27260156	CORL105	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.025812340974622927	[1948]	[2264,2082,2463,2190]	0	hSpCas9	negative selection	6517166
48815982	48816005	X	+	27260156	CORL105	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.2916509536032752	[449]	[675,626,609,661]	5	hSpCas9	negative selection	6517167
48802911	48802934	X	-	27260156	CORL105	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.4688020495837366	[906]	[1464,1343,1867,1265]	8	hSpCas9	negative selection	6581426
48816168	48816191	X	+	27260156	CORL105	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.15746768849261505	[247]	[235,259,258,284]	-3	hSpCas9	negative selection	6581427
48815982	48816005	X	-	27260156	CORL105	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.030270858407764112	[739]	[909,739,1041,735]	0	hSpCas9	negative selection	6581428
48816159	48816182	X	-	27260156	HS294T	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.2604610075667346	[132]	[78,43,55,66]	3	hSpCas9	negative selection	6638416
48802975	48802998	X	-	27260156	HS294T	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.20949350239587483	[1948]	[874,853,760,1016]	3	hSpCas9	negative selection	6638417
48815982	48816005	X	+	27260156	HS294T	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.4043772350282704	[449]	[306,171,189,248]	5	hSpCas9	negative selection	6638418
48802911	48802934	X	-	27260156	HS294T	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.32510878755477046	[906]	[463,469,420,388]	4	hSpCas9	negative selection	6702677
48816168	48816191	X	+	27260156	HS294T	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.5633342059503526	[247]	[108,50,113,329]	7	hSpCas9	negative selection	6702678
48815982	48816005	X	-	27260156	HS294T	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.16777247346565527	[739]	[222,267,287,238]	-2	hSpCas9	negative selection	6702679
48816159	48816182	X	-	27260156	HCC44	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.18601959966281756	[132]	[170,128,167,71]	-3	hSpCas9	negative selection	6759667
48802975	48802998	X	-	27260156	HCC44	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.15568495226763313	[1948]	[2072,1795,2238,1873]	-3	hSpCas9	negative selection	6759668
48815982	48816005	X	+	27260156	HCC44	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.2918085307890278	[449]	[1042,485,615,405]	5	hSpCas9	negative selection	6759669
48802911	48802934	X	-	27260156	HCC44	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.5063382138731882	[906]	[1405,1482,1462,1456]	8	hSpCas9	negative selection	6823928
48816168	48816191	X	+	27260156	HCC44	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.0007755966290542426	[247]	[342,150,398,270]	0	hSpCas9	negative selection	6823929
48815982	48816005	X	-	27260156	HCC44	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.35765600873996406	[739]	[830,672,663,460]	-5	hSpCas9	negative selection	6823930
48816159	48816182	X	-	27260156	G402	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.3280170476894706	[132]	[217,137,66,107]	-4	hSpCas9	negative selection	6880918
48802975	48802998	X	-	27260156	G402	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.12664942747782582	[1948]	[1789,1792,2604,2425]	-1	hSpCas9	negative selection	6880919
48815982	48816005	X	+	27260156	G402	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.10219616316277647	[449]	[422,507,709,680]	1	hSpCas9	negative selection	6880920
48802911	48802934	X	-	27260156	G402	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.9936980436556715	[906]	[2251,2565,1968,2054]	9	hSpCas9	negative selection	6945179
48816168	48816191	X	+	27260156	G402	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.1191008210266925	[247]	[389,367,209,171]	-1	hSpCas9	negative selection	6945180
48815982	48816005	X	-	27260156	G402	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.017382107680225745	[739]	[1233,522,816,1012]	0	hSpCas9	negative selection	6945181
48816159	48816182	X	-	27260156	L33	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.06893101298127569	[132]	[81,34,163,80]	-1	hSpCas9	negative selection	7002169
48802975	48802998	X	-	27260156	L33	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.14896577587319237	[1948]	[1973,903,1403,2233]	3	hSpCas9	negative selection	7002170
48815982	48816005	X	+	27260156	L33	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.159190014607548	[449]	[586,209,300,429]	3	hSpCas9	negative selection	7002171
48802911	48802934	X	-	27260156	L33	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.08707732593503281	[906]	[939,367,577,1094]	2	hSpCas9	negative selection	7066430
48816168	48816191	X	+	27260156	L33	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.19936102798407462	[247]	[275,70,142,185]	-4	hSpCas9	negative selection	7066431
48815982	48816005	X	-	27260156	L33	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.16814755668674503	[739]	[588,263,438,703]	-4	hSpCas9	negative selection	7066432
48816159	48816182	X	-	27260156	K562	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.526261022209698	[132]	[103,287,51,228]	6	hSpCas9	negative selection	7123420
48802975	48802998	X	-	27260156	K562	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.4325402712228843	[1948]	[1228,2029,1060,882]	-5	hSpCas9	negative selection	7123421
48815982	48816005	X	+	27260156	K562	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.25751076101877235	[449]	[371,756,320,464]	3	hSpCas9	negative selection	7123422
48802911	48802934	X	-	27260156	K562	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.425033174289156	[906]	[1221,1236,1101,808]	5	hSpCas9	negative selection	7187681
48816168	48816191	X	+	27260156	K562	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.4931764401277806	[247]	[154,339,64,82]	-5	hSpCas9	negative selection	7187682
48815982	48816005	X	-	27260156	K562	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.10661014714619876	[739]	[499,503,850,571]	-1	hSpCas9	negative selection	7187683
48816159	48816182	X	-	27260156	HT29	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.5310488564970042	[132]	[98,89,188,70]	-7	hSpCas9	negative selection	7244671
48802975	48802998	X	-	27260156	HT29	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.014323159534736174	[1948]	[2859,2543,2273,1976]	0	hSpCas9	negative selection	7244672
48815982	48816005	X	+	27260156	HT29	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.02736390575231274	[449]	[511,560,495,642]	0	hSpCas9	negative selection	7244673
48802911	48802934	X	-	27260156	HT29	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3764766973316229	[906]	[1422,1717,1437,1189]	7	hSpCas9	negative selection	7308932
48816168	48816191	X	+	27260156	HT29	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.15118746453032128	[247]	[273,437,402,237]	3	hSpCas9	negative selection	7308933
48815982	48816005	X	-	27260156	HT29	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.022885000127062294	[739]	[911,1026,784,831]	0	hSpCas9	negative selection	7308934
48816159	48816182	X	-	27260156	MHHES1	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.3460691114992933	[132]	[266,127,40,63]	-6	hSpCas9	negative selection	7365922
48802975	48802998	X	-	27260156	MHHES1	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.156507392119567	[1948]	[2029,1834,2175,1820]	-3	hSpCas9	negative selection	7365923
48815982	48816005	X	+	27260156	MHHES1	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.24267246814525956	[449]	[811,654,654,352]	4	hSpCas9	negative selection	7365924
48802911	48802934	X	-	27260156	MHHES1	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3960768934517134	[906]	[1157,1654,1405,1175]	7	hSpCas9	negative selection	7430183
48816168	48816191	X	+	27260156	MHHES1	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.11721879278386049	[247]	[314,361,178,198]	-2	hSpCas9	negative selection	7430184
48815982	48816005	X	-	27260156	MHHES1	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.07303226260612927	[739]	[1010,851,766,598]	-1	hSpCas9	negative selection	7430185
48816159	48816182	X	-	27260156	MEWO	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.31873073083151127	[132]	[123,92,86]	-6	hSpCas9	negative selection	7487173
48802975	48802998	X	-	27260156	MEWO	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.07190971890978437	[1948]	[1839,1582,1801]	-1	hSpCas9	negative selection	7487174
48815982	48816005	X	+	27260156	MEWO	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.41901386607730157	[449]	[572,663,452]	8	hSpCas9	negative selection	7487175
48802911	48802934	X	-	27260156	MEWO	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.000821142774534156	[906]	[1084,569,938]	0	hSpCas9	negative selection	7551434
48816168	48816191	X	+	27260156	MEWO	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.06454821710937675	[247]	[253,253,221]	1	hSpCas9	negative selection	7551435
48815982	48816005	X	-	27260156	MEWO	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.28671544930620846	[739]	[540,637,517]	-6	hSpCas9	negative selection	7551436
48816159	48816182	X	-	27260156	LNCAPCLONEFGC	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.030100136078623496	[132]	[91,79,212,103]	0	hSpCas9	negative selection	7608424
48802975	48802998	X	-	27260156	LNCAPCLONEFGC	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.11697624106857951	[1948]	[1728,1797,2301,1896]	1	hSpCas9	negative selection	7608425
48815982	48816005	X	+	27260156	LNCAPCLONEFGC	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.3747587587012764	[449]	[324,676,676,450]	6	hSpCas9	negative selection	7608426
48802911	48802934	X	-	27260156	LNCAPCLONEFGC	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.506695843253919	[906]	[1265,850,1358,1239]	7	hSpCas9	negative selection	7672685
48816168	48816191	X	+	27260156	LNCAPCLONEFGC	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.19273908005263418	[247]	[217,387,182,218]	3	hSpCas9	negative selection	7672686
48815982	48816005	X	-	27260156	LNCAPCLONEFGC	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.06513658501879493	[739]	[655,692,868,612]	1	hSpCas9	negative selection	7672687
48816159	48816182	X	-	27260156	PANC0327	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.7194889848448174	[132]	[54,46,166,19]	-7	hSpCas9	negative selection	7729675
48802975	48802998	X	-	27260156	PANC0327	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.19715088393805447	[1948]	[2485,1987,2101,1403]	3	hSpCas9	negative selection	7729676
48815982	48816005	X	+	27260156	PANC0327	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.034561344103217456	[449]	[547,318,556,236]	0	hSpCas9	negative selection	7729677
48802911	48802934	X	-	27260156	PANC0327	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.24894023930381737	[906]	[1023,766,1214,853]	3	hSpCas9	negative selection	7793936
48816168	48816191	X	+	27260156	PANC0327	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.042908535865058495	[247]	[240,293,103,260]	0	hSpCas9	negative selection	7793937
48815982	48816005	X	-	27260156	PANC0327	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.0806333489518628	[739]	[762,396,712,653]	-1	hSpCas9	negative selection	7793938
48816159	48816182	X	-	27260156	NCIH2009	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-1.0033148984303994	[132]	[119,110,51]	-8	hSpCas9	negative selection	7850926
48802975	48802998	X	-	27260156	NCIH2009	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.05896987772483908	[1948]	[3561,2279,2188]	-1	hSpCas9	negative selection	7850927
48815982	48816005	X	+	27260156	NCIH2009	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.47282142543081573	[449]	[1058,873,719]	6	hSpCas9	negative selection	7850928
48802911	48802934	X	-	27260156	NCIH2009	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.6377404866914163	[906]	[2445,1551,2014]	8	hSpCas9	negative selection	7915187
48816168	48816191	X	+	27260156	NCIH2009	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.2548304196807787	[247]	[467,434,346]	3	hSpCas9	negative selection	7915188
48815982	48816005	X	-	27260156	NCIH2009	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.1101661451130912	[739]	[1133,893,879]	-1	hSpCas9	negative selection	7915189
48816159	48816182	X	-	27260156	NCIH1373	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.5781764292860321	[132]	[91,93,49,43]	-5	hSpCas9	negative selection	7972177
48802975	48802998	X	-	27260156	NCIH1373	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.0838467904311817	[1948]	[2741,2739,2256,388]	0	hSpCas9	negative selection	7972178
48815982	48816005	X	+	27260156	NCIH1373	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.7121832532774096	[449]	[1315,346,1116,165]	7	hSpCas9	negative selection	7972179
48802911	48802934	X	-	27260156	NCIH1373	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	1.0236400013050084	[906]	[2285,2008,2000,524]	9	hSpCas9	negative selection	8036438
48816168	48816191	X	+	27260156	NCIH1373	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.765755993193355	[247]	[266,284,707,162]	7	hSpCas9	negative selection	8036439
48815982	48816005	X	-	27260156	NCIH1373	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.5318689517776665	[739]	[1383,894,1195,364]	5	hSpCas9	negative selection	8036440
48816159	48816182	X	-	27260156	PATU8902	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.10963779729606049	[132]	[166,167,183,161]	-1	hSpCas9	negative selection	8093428
48802975	48802998	X	-	27260156	PATU8902	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.5832285303265574	[1948]	[4127,4707,2603,5325]	6	hSpCas9	negative selection	8093429
48815982	48816005	X	+	27260156	PATU8902	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	1.0128060089633386	[449]	[1425,1182,1408,952]	9	hSpCas9	negative selection	8093430
48802911	48802934	X	-	27260156	PATU8902	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.9521709993294749	[906]	[1814,2598,2364,3082]	8	hSpCas9	negative selection	8157689
48816168	48816191	X	+	27260156	PATU8902	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.7639967407323558	[247]	[537,570,85,1370]	7	hSpCas9	negative selection	8157690
48815982	48816005	X	-	27260156	PATU8902	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.7250297118133702	[739]	[1926,1469,1472,2024]	7	hSpCas9	negative selection	8157691
48816159	48816182	X	-	27260156	PANC1	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.3532975405123504	[132]	[63,80,52,146]	-5	hSpCas9	negative selection	8214679
48802975	48802998	X	-	27260156	PANC1	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.0648972789014497	[1948]	[1639,2303,1698,1490]	1	hSpCas9	negative selection	8214680
48815982	48816005	X	+	27260156	PANC1	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.034461851018584705	[449]	[416,482,433,279]	0	hSpCas9	negative selection	8214681
48802911	48802934	X	-	27260156	PANC1	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3970486773378874	[906]	[1119,1273,802,948]	6	hSpCas9	negative selection	8278940
48816168	48816191	X	+	27260156	PANC1	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.09915458458463888	[247]	[194,300,237,195]	1	hSpCas9	negative selection	8278941
48815982	48816005	X	-	27260156	PANC1	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.09395866151079835	[739]	[788,708,563,647]	1	hSpCas9	negative selection	8278942
48816159	48816182	X	-	27260156	PANC0813	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.05144053563329032	[132]	[231,155,72,148]	-1	hSpCas9	negative selection	8335930
48802975	48802998	X	-	27260156	PANC0813	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.13585718839166683	[1948]	[2732,2338,2512,2493]	2	hSpCas9	negative selection	8335931
48815982	48816005	X	+	27260156	PANC0813	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.17814002736247525	[449]	[643,592,657,505]	3	hSpCas9	negative selection	8335932
48802911	48802934	X	-	27260156	PANC0813	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.13726634837887053	[906]	[1270,1213,1061,1147]	2	hSpCas9	negative selection	8400191
48816168	48816191	X	+	27260156	PANC0813	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.3059041344525296	[247]	[383,582,220,258]	5	hSpCas9	negative selection	8400192
48815982	48816005	X	-	27260156	PANC0813	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.10300092532981164	[739]	[1054,705,1004,975]	1	hSpCas9	negative selection	8400193
48816159	48816182	X	-	27260156	RDES	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.004324346149918501	[132]	[168,107,166,167]	0	hSpCas9	negative selection	8457181
48802975	48802998	X	-	27260156	RDES	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.10015064360605686	[1948]	[1757,1886,2148,2691]	-2	hSpCas9	negative selection	8457182
48815982	48816005	X	+	27260156	RDES	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.34747761740594935	[449]	[490,582,628,1007]	5	hSpCas9	negative selection	8457183
48802911	48802934	X	-	27260156	RDES	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.6349071862438334	[906]	[1312,1619,1639,1977]	8	hSpCas9	negative selection	8521442
48816168	48816191	X	+	27260156	RDES	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.05644008412879342	[247]	[182,337,190,407]	-1	hSpCas9	negative selection	8521443
48815982	48816005	X	-	27260156	RDES	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.05878005483652349	[739]	[692,714,860,1384]	1	hSpCas9	negative selection	8521444
48816159	48816182	X	-	27260156	PC3	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.015173327496134315	[132]	[106,65,226,161]	0	hSpCas9	negative selection	8578432
48802975	48802998	X	-	27260156	PC3	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.08039132478224897	[1948]	[1283,1878,2724,1848]	-2	hSpCas9	negative selection	8578433
48815982	48816005	X	+	27260156	PC3	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.0012264680900554853	[449]	[239,424,717,574]	0	hSpCas9	negative selection	8578434
48802911	48802934	X	-	27260156	PC3	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.36442198478171806	[906]	[881,701,2344,1207]	7	hSpCas9	negative selection	8642693
48816168	48816191	X	+	27260156	PC3	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.1718985484851424	[247]	[150,147,475,213]	-4	hSpCas9	negative selection	8642694
48815982	48816005	X	-	27260156	PC3	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.046001736536297355	[739]	[428,849,1509,614]	1	hSpCas9	negative selection	8642695
48816159	48816182	X	-	27260156	PATU8988T	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.3529379756874551	[132]	[106,105,90,98]	-5	hSpCas9	negative selection	8699683
48802975	48802998	X	-	27260156	PATU8988T	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.10645579906881997	[1948]	[2205,2083,1939,1873]	1	hSpCas9	negative selection	8699684
48815982	48816005	X	+	27260156	PATU8988T	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.17562513698216123	[449]	[345,534,536,554]	3	hSpCas9	negative selection	8699685
48802911	48802934	X	-	27260156	PATU8988T	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.37130178855359386	[906]	[781,1275,1350,1135]	6	hSpCas9	negative selection	8763944
48816168	48816191	X	+	27260156	PATU8988T	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.3750990672621224	[247]	[158,576,146,393]	6	hSpCas9	negative selection	8763945
48815982	48816005	X	-	27260156	PATU8988T	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.15258523760780662	[739]	[675,1052,341,535]	-3	hSpCas9	negative selection	8763946
48816159	48816182	X	-	27260156	T47D	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.05695239984288958	[132]	[185,149,167,140]	1	hSpCas9	negative selection	8820934
48802975	48802998	X	-	27260156	T47D	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.11834430938800122	[1948]	[2124,1791,2134,2347]	-3	hSpCas9	negative selection	8820935
48815982	48816005	X	+	27260156	T47D	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	-0.000252184446892581	[449]	[551,485,489,573]	0	hSpCas9	negative selection	8820936
48802911	48802934	X	-	27260156	T47D	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3957931129610559	[906]	[1456,1353,1385,1365]	8	hSpCas9	negative selection	8885195
48816168	48816191	X	+	27260156	T47D	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.10435124049697819	[247]	[283,256,342,363]	2	hSpCas9	negative selection	8885196
48815982	48816005	X	-	27260156	T47D	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.014143947530034562	[739]	[939,731,851,973]	0	hSpCas9	negative selection	8885197
48816159	48816182	X	-	27260156	SU8686	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.18089276506895935	[132]	[160,114,121,50]	-3	hSpCas9	negative selection	8942185
48802975	48802998	X	-	27260156	SU8686	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.1301386424860953	[1948]	[1708,1554,1933,1913]	-2	hSpCas9	negative selection	8942186
48815982	48816005	X	+	27260156	SU8686	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.04612082282478726	[449]	[466,418,521,432]	0	hSpCas9	negative selection	8942187
48802911	48802934	X	-	27260156	SU8686	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3461232152844098	[906]	[1163,941,1312,1178]	6	hSpCas9	negative selection	9006446
48816168	48816191	X	+	27260156	SU8686	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.3054075482750548	[247]	[247,228,280,502]	5	hSpCas9	negative selection	9006447
48815982	48816005	X	-	27260156	SU8686	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.139984567714164	[739]	[557,599,671,884]	-2	hSpCas9	negative selection	9006448
48816159	48816182	X	-	27260156	SKES1	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.09969162326084713	[132]	[100,191,188,90]	2	hSpCas9	negative selection	9063436
48802975	48802998	X	-	27260156	SKES1	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.05741834040438465	[1948]	[2237,2047,1805,1481]	-1	hSpCas9	negative selection	9063437
48815982	48816005	X	+	27260156	SKES1	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.06345092487763178	[449]	[465,524,404,480]	1	hSpCas9	negative selection	9063438
48802911	48802934	X	-	27260156	SKES1	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.2784032436371111	[906]	[1314,1352,956,845]	6	hSpCas9	negative selection	9127697
48816168	48816191	X	+	27260156	SKES1	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.11746810661802332	[247]	[346,232,189,164]	-3	hSpCas9	negative selection	9127698
48815982	48816005	X	-	27260156	SKES1	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.01872108665875649	[739]	[657,760,860,630]	0	hSpCas9	negative selection	9127699
48816159	48816182	X	-	27260156	TOV112D	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	0.11731357042963442	[132]	[205,150,100,126]	2	hSpCas9	negative selection	9184687
48802975	48802998	X	-	27260156	TOV112D	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.15128037593389698	[1948]	[1367,2281,2002,1478]	-3	hSpCas9	negative selection	9184688
48815982	48816005	X	+	27260156	TOV112D	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.16535238137934177	[449]	[568,734,427,354]	3	hSpCas9	negative selection	9184689
48802911	48802934	X	-	27260156	TOV112D	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.3519361540255219	[906]	[1230,1589,999,932]	6	hSpCas9	negative selection	9248948
48816168	48816191	X	+	27260156	TOV112D	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.012334154612623771	[247]	[384,102,394,97]	0	hSpCas9	negative selection	9248949
48815982	48816005	X	-	27260156	TOV112D	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.20348461548277802	[739]	[645,1001,481,534]	-4	hSpCas9	negative selection	9248950
48816159	48816182	X	-	27260156	TC71	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.1632230259058296	[132]	[75,133,190,105]	-4	hSpCas9	negative selection	9305938
48802975	48802998	X	-	27260156	TC71	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	0.0482228883703506	[1948]	[2156,1965,2067,2471]	1	hSpCas9	negative selection	9305939
48815982	48816005	X	+	27260156	TC71	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.06752182058089082	[449]	[512,442,458,614]	1	hSpCas9	negative selection	9305940
48802911	48802934	X	-	27260156	TC71	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.4347783646619532	[906]	[1054,1566,1246,1400]	8	hSpCas9	negative selection	9370199
48816168	48816191	X	+	27260156	TC71	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	-0.15796278726131996	[247]	[253,156,257,285]	-4	hSpCas9	negative selection	9370200
48815982	48816005	X	-	27260156	TC71	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	-0.18051331654292307	[739]	[595,773,591,852]	-5	hSpCas9	negative selection	9370201
48816159	48816182	X	-	27260156	TC32	viability	ACATGATCCGCAAGATGCGCTGG	HDAC6	ENSG00000094631	-0.3187926909799992	[132]	[106,50,129,131]	-5	hSpCas9	negative selection	9427189
48802975	48802998	X	-	27260156	TC32	viability	TCCCTTGCAGTCCCACGATTAGG	HDAC6	ENSG00000094631	-0.057231106280368316	[1948]	[1516,1456,2185,2007]	-1	hSpCas9	negative selection	9427190
48815982	48816005	X	+	27260156	TC32	viability	CCAGTGCTACAGTCTCGCACAGG	HDAC6	ENSG00000094631	0.40725503068312724	[449]	[438,543,720,552]	7	hSpCas9	negative selection	9427191
48802911	48802934	X	-	27260156	TC32	viability	CTTCTTTACCTCCGCTAGATTGG	HDAC6	ENSG00000094631	0.4144039952876277	[906]	[894,838,1469,1495]	7	hSpCas9	negative selection	9491450
48816168	48816191	X	+	27260156	TC32	viability	CTTGCGGATCATGTGCCGTCTGG	HDAC6	ENSG00000094631	0.018245338371682407	[247]	[184,218,305,244]	0	hSpCas9	negative selection	9491451
48815982	48816005	X	-	27260156	TC32	viability	CCTGTGCGAGACTGTAGCACTGG	HDAC6	ENSG00000094631	0.0569388200113935	[739]	[706,470,861,945]	1	hSpCas9	negative selection	9491452
48801923	48801946	X	+	27869803	HPAFII	viability after 27 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.21418393915045902	[332]	[123,268,NaN]	1	hSpCas9	negative selection	9608943
48802772	48802795	X	-	27869803	HPAFII	viability after 27 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.25147006559635177	[146]	[199,1,NaN]	2	hSpCas9	negative selection	9608944
48802945	48802968	X	+	27869803	HPAFII	viability after 27 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.0227376874160437	[139]	[268,49,NaN]	8	hSpCas9	negative selection	9608945
48803202	48803225	X	-	27869803	HPAFII	viability after 27 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.7293141351980721	[176]	[114,186,NaN]	6	hSpCas9	negative selection	9608946
48805627	48805650	X	+	27869803	HPAFII	viability after 27 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.3904746308382596	[594]	[734,890,NaN]	9	hSpCas9	negative selection	9608947
48806422	48806445	X	-	27869803	HPAFII	viability after 27 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.31448365104858655	[385]	[325,190,NaN]	2	hSpCas9	negative selection	9608948
48801923	48801946	X	+	27869803	HPAFII	viability after 15 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.17194733847390092	[332]	[425,388,NaN]	2	hSpCas9	negative selection	9691392
48802772	48802795	X	-	27869803	HPAFII	viability after 15 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.32987067977476603	[146]	[240,53,NaN]	-4	hSpCas9	negative selection	9691393
48802945	48802968	X	+	27869803	HPAFII	viability after 15 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.6111130025597069	[139]	[280,197,NaN]	7	hSpCas9	negative selection	9691394
48803202	48803225	X	-	27869803	HPAFII	viability after 15 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	0.10064557811171371	[176]	[256,170,NaN]	1	hSpCas9	negative selection	9691395
48805627	48805650	X	+	27869803	HPAFII	viability after 15 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.978271403344845	[594]	[1548,1079,NaN]	9	hSpCas9	negative selection	9691396
48806422	48806445	X	-	27869803	HPAFII	viability after 15 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.24586851161423923	[385]	[622,179,NaN]	-3	hSpCas9	negative selection	9691397
48801923	48801946	X	+	27869803	ASPC1	viability after 36 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	1.1594573737826033	[668]	[792,145,623]	9	hSpCas9	negative selection	9773841
48802772	48802795	X	-	27869803	ASPC1	viability after 36 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.07363656822231035	[291]	[173,84,76]	0	hSpCas9	negative selection	9773842
48802945	48802968	X	+	27869803	ASPC1	viability after 36 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.2899529451890763	[386]	[380,205,389]	9	hSpCas9	negative selection	9773843
48803202	48803225	X	-	27869803	ASPC1	viability after 36 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-0.7920890295988571	[525]	[142,134,55]	-7	hSpCas9	negative selection	9773844
48805627	48805650	X	+	27869803	ASPC1	viability after 36 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.006250953416102	[1509]	[1208,1174,849]	8	hSpCas9	negative selection	9773845
48806422	48806445	X	-	27869803	ASPC1	viability after 36 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.025324382911772192	[1155]	[795,480,44]	0	hSpCas9	negative selection	9773846
48801923	48801946	X	+	27869803	PATU8988S	viability after 35 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	1.241373561166205	[565]	[513,563,NaN]	9	hSpCas9	negative selection	9856290
48802772	48802795	X	-	27869803	PATU8988S	viability after 35 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.0068494575960680315	[241]	[66,128,NaN]	0	hSpCas9	negative selection	9856291
48802945	48802968	X	+	27869803	PATU8988S	viability after 35 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.06550190473631123	[402]	[102,236,NaN]	0	hSpCas9	negative selection	9856292
48803202	48803225	X	-	27869803	PATU8988S	viability after 35 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.3936838850389566	[325]	[36,62,NaN]	-8	hSpCas9	negative selection	9856293
48805627	48805650	X	+	27869803	PATU8988S	viability after 35 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.30689216369347805	[1441]	[906,528,NaN]	3	hSpCas9	negative selection	9856294
48806422	48806445	X	-	27869803	PATU8988S	viability after 35 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.4096396008585649	[997]	[719,346,NaN]	4	hSpCas9	negative selection	9856295
48801923	48801946	X	+	27869803	PATU8988S	viability after 31 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	1.2419288978737701	[565]	[469,614,NaN]	9	hSpCas9	negative selection	9938739
48802772	48802795	X	-	27869803	PATU8988S	viability after 31 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	-0.10137922069643701	[241]	[30,164,NaN]	-1	hSpCas9	negative selection	9938740
48802945	48802968	X	+	27869803	PATU8988S	viability after 31 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.019716128911175967	[402]	[88,256,NaN]	0	hSpCas9	negative selection	9938741
48803202	48803225	X	-	27869803	PATU8988S	viability after 31 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	-1.5934877674802572	[325]	[17,74,NaN]	-8	hSpCas9	negative selection	9938742
48805627	48805650	X	+	27869803	PATU8988S	viability after 31 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	0.4538496293218872	[1441]	[765,814,NaN]	5	hSpCas9	negative selection	9938743
48806422	48806445	X	-	27869803	PATU8988S	viability after 31 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.3884470015823106	[997]	[640,367,NaN]	5	hSpCas9	negative selection	9938744
48801923	48801946	X	+	27869803	HPAFII	viability after 35 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.4200351512854478	[332]	[154,304,NaN]	2	hSpCas9	negative selection	10021188
48802772	48802795	X	-	27869803	HPAFII	viability after 35 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.7150686382510717	[146]	[211,20,NaN]	5	hSpCas9	negative selection	10021189
48802945	48802968	X	+	27869803	HPAFII	viability after 35 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.9324062595290779	[139]	[373,153,NaN]	9	hSpCas9	negative selection	10021190
48803202	48803225	X	-	27869803	HPAFII	viability after 35 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	1.2689480467898264	[176]	[87,359,NaN]	8	hSpCas9	negative selection	10021191
48805627	48805650	X	+	27869803	HPAFII	viability after 35 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.6580084922310085	[594]	[816,1100,NaN]	9	hSpCas9	negative selection	10021192
48806422	48806445	X	-	27869803	HPAFII	viability after 35 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	0.1957894657426068	[385]	[204,244,NaN]	1	hSpCas9	negative selection	10021193
48801923	48801946	X	+	27869803	HPAFII	viability after 31 days	GCTGCGTCCAATGAGTGGAGCGG	HDAC6	ENSG00000094631	0.1645041058615861	[332]	[174,246,NaN]	1	hSpCas9	negative selection	10103637
48802772	48802795	X	-	27869803	HPAFII	viability after 31 days	GGGCCTCACCGAAGTGACACTGG	HDAC6	ENSG00000094631	0.26378392484101754	[146]	[155,36,NaN]	2	hSpCas9	negative selection	10103638
48802945	48802968	X	+	27869803	HPAFII	viability after 31 days	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.4965066603891404	[139]	[292,143,NaN]	9	hSpCas9	negative selection	10103639
48803202	48803225	X	-	27869803	HPAFII	viability after 31 days	AGCCTCACCTGTCATCCCAGAGG	HDAC6	ENSG00000094631	1.0575590105365578	[176]	[111,309,NaN]	7	hSpCas9	negative selection	10103640
48805627	48805650	X	+	27869803	HPAFII	viability after 31 days	CCAGGCCCGGTTTGCTGAAAAGG	HDAC6	ENSG00000094631	1.8035973359080235	[594]	[1035,1306,NaN]	9	hSpCas9	negative selection	10103641
48806422	48806445	X	-	27869803	HPAFII	viability after 31 days	CGTAGGTGTCTGCTAGGACACGG	HDAC6	ENSG00000094631	-0.1452174604252892	[385]	[237,149,NaN]	-1	hSpCas9	negative selection	10103642
48802945	48802968	X	+	28162770	P31FUJ	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.05460777668875172	[312]	[381]	0	hSpCas9	negative selection	10167928
48822686	48822709	X	-	28162770	P31FUJ	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.22713345432768658	[253]	[254]	-2	hSpCas9	negative selection	10167929
48815894	48815917	X	+	28162770	P31FUJ	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.9697677985805848	[269]	[161]	-6	hSpCas9	negative selection	10167930
48822673	48822696	X	-	28162770	P31FUJ	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-2.75337411786558	[240]	[41]	-9	hSpCas9	negative selection	10167931
48802762	48802785	X	-	28162770	P31FUJ	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.4019829949453494	[350]	[544]	4	hSpCas9	negative selection	10167932
48808116	48808139	X	+	28162770	P31FUJ	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.3778251797001248	[259]	[396]	4	hSpCas9	negative selection	10167933
48814511	48814534	X	-	28162770	P31FUJ	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.4540399103259911	[368]	[593]	5	hSpCas9	negative selection	10167934
48814840	48814863	X	-	28162770	P31FUJ	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.20583515681410924	[52]	[53]	-2	hSpCas9	negative selection	10167935
48816603	48816626	X	-	28162770	P31FUJ	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.10303346383607892	[350]	[442]	1	hSpCas9	negative selection	10167936
48822651	48822674	X	-	28162770	P31FUJ	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.07175875850289563	[233]	[288]	0	hSpCas9	negative selection	10167937
48802945	48802968	X	+	28162770	TF1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10337294
48822686	48822709	X	-	28162770	TF1	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10337295
48815894	48815917	X	+	28162770	TF1	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10337296
48822673	48822696	X	-	28162770	TF1	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10337297
48802762	48802785	X	-	28162770	TF1	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	NaN	[NaN]	[341]	1	hSpCas9	negative selection	10337298
48808116	48808139	X	+	28162770	TF1	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10337299
48814511	48814534	X	-	28162770	TF1	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10337300
48814840	48814863	X	-	28162770	TF1	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10337301
48816603	48816626	X	-	28162770	TF1	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	NaN	[NaN]	[353]	1	hSpCas9	negative selection	10337302
48822651	48822674	X	-	28162770	TF1	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10337303
48802945	48802968	X	+	28162770	SKM1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.5172043882971923	[82]	[209]	5	hSpCas9	negative selection	10506660
48822686	48822709	X	-	28162770	SKM1	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.8935549590470396	[61]	[58]	-6	hSpCas9	negative selection	10506661
48815894	48815917	X	+	28162770	SKM1	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.184571777406714	[71]	[55]	-7	hSpCas9	negative selection	10506662
48822673	48822696	X	-	28162770	SKM1	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.3554338981030796	[54]	[37]	-7	hSpCas9	negative selection	10506663
48802762	48802785	X	-	28162770	SKM1	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	-0.550328373914339	[110]	[133]	-4	hSpCas9	negative selection	10506664
48808116	48808139	X	+	28162770	SKM1	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.07655303841844874	[80]	[150]	0	hSpCas9	negative selection	10506665
48814511	48814534	X	-	28162770	SKM1	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	-0.22816104595439657	[107]	[162]	-2	hSpCas9	negative selection	10506666
48814840	48814863	X	-	28162770	SKM1	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.08488889758651297	[7]	[14]	0	hSpCas9	negative selection	10506667
48816603	48816626	X	-	28162770	SKM1	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.21842351913350228	[76]	[116]	-2	hSpCas9	negative selection	10506668
48822651	48822674	X	-	28162770	SKM1	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.23008643665908235	[68]	[103]	-2	hSpCas9	negative selection	10506669
48802945	48802968	X	+	28162770	SKM1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.5172043882971923	[82]	[209]	5	hSpCas9	negative selection	10676026
48822686	48822709	X	-	28162770	SKM1	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.8935549590470396	[61]	[58]	-6	hSpCas9	negative selection	10676027
48815894	48815917	X	+	28162770	SKM1	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.184571777406714	[71]	[55]	-7	hSpCas9	negative selection	10676028
48822673	48822696	X	-	28162770	SKM1	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.3554338981030796	[54]	[37]	-7	hSpCas9	negative selection	10676029
48802762	48802785	X	-	28162770	SKM1	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	-0.550328373914339	[110]	[133]	-4	hSpCas9	negative selection	10676030
48808116	48808139	X	+	28162770	SKM1	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.07655303841844874	[80]	[150]	0	hSpCas9	negative selection	10676031
48814511	48814534	X	-	28162770	SKM1	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	-0.22816104595439657	[107]	[162]	-2	hSpCas9	negative selection	10676032
48814840	48814863	X	-	28162770	SKM1	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.08488889758651297	[7]	[14]	0	hSpCas9	negative selection	10676033
48816603	48816626	X	-	28162770	SKM1	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.21842351913350228	[76]	[116]	-2	hSpCas9	negative selection	10676034
48822651	48822674	X	-	28162770	SKM1	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.23008643665908235	[68]	[103]	-2	hSpCas9	negative selection	10676035
48802945	48802968	X	+	28162770	PL21	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	-1.1757272875088458	[326]	[62]	-7	hSpCas9	negative selection	10845392
48822686	48822709	X	-	28162770	PL21	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	0.08174491368708978	[164]	[75]	0	hSpCas9	negative selection	10845393
48815894	48815917	X	+	28162770	PL21	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	0.7538059847209377	[232]	[170]	6	hSpCas9	negative selection	10845394
48822673	48822696	X	-	28162770	PL21	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.4969332525533734	[213]	[32]	-7	hSpCas9	negative selection	10845395
48802762	48802785	X	-	28162770	PL21	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.7507746515305387	[481]	[352]	6	hSpCas9	negative selection	10845396
48808116	48808139	X	+	28162770	PL21	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.06889508121106752	[229]	[104]	0	hSpCas9	negative selection	10845397
48814511	48814534	X	-	28162770	PL21	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.7277198930745074	[264]	[190]	6	hSpCas9	negative selection	10845398
48814840	48814863	X	-	28162770	PL21	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-3.7998603855106805	[31]	[0]	-9	hSpCas9	negative selection	10845399
48816603	48816626	X	-	28162770	PL21	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.4039348169484379	[289]	[166]	3	hSpCas9	negative selection	10845400
48822651	48822674	X	-	28162770	PL21	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.8314950206949274	[203]	[157]	7	hSpCas9	negative selection	10845401
48802945	48802968	X	+	28162770	P31FUJ	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.05460777668875172	[312]	[381]	0	hSpCas9	negative selection	11014758
48822686	48822709	X	-	28162770	P31FUJ	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.22713345432768658	[253]	[254]	-2	hSpCas9	negative selection	11014759
48815894	48815917	X	+	28162770	P31FUJ	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.9697677985805848	[269]	[161]	-6	hSpCas9	negative selection	11014760
48822673	48822696	X	-	28162770	P31FUJ	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-2.75337411786558	[240]	[41]	-9	hSpCas9	negative selection	11014761
48802762	48802785	X	-	28162770	P31FUJ	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.4019829949453494	[350]	[544]	4	hSpCas9	negative selection	11014762
48808116	48808139	X	+	28162770	P31FUJ	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.3778251797001248	[259]	[396]	4	hSpCas9	negative selection	11014763
48814511	48814534	X	-	28162770	P31FUJ	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.4540399103259911	[368]	[593]	5	hSpCas9	negative selection	11014764
48814840	48814863	X	-	28162770	P31FUJ	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.20583515681410924	[52]	[53]	-2	hSpCas9	negative selection	11014765
48816603	48816626	X	-	28162770	P31FUJ	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.10303346383607892	[350]	[442]	1	hSpCas9	negative selection	11014766
48822651	48822674	X	-	28162770	P31FUJ	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.07175875850289563	[233]	[288]	0	hSpCas9	negative selection	11014767
48802945	48802968	X	+	28162770	OCIAML5	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.6423583834435567	[136]	[385]	5	hSpCas9	negative selection	11184124
48822686	48822709	X	-	28162770	OCIAML5	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.9924392272285492	[150]	[136]	-6	hSpCas9	negative selection	11184125
48815894	48815917	X	+	28162770	OCIAML5	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-2.4680559672057774	[140]	[45]	-8	hSpCas9	negative selection	11184126
48822673	48822696	X	-	28162770	OCIAML5	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.4650434477547498	[181]	[118]	-7	hSpCas9	negative selection	11184127
48802762	48802785	X	-	28162770	OCIAML5	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.13625162408836755	[185]	[368]	1	hSpCas9	negative selection	11184128
48808116	48808139	X	+	28162770	OCIAML5	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.16869198930280055	[137]	[279]	1	hSpCas9	negative selection	11184129
48814511	48814534	X	-	28162770	OCIAML5	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.5853387414433013	[215]	[584]	5	hSpCas9	negative selection	11184130
48814840	48814863	X	-	28162770	OCIAML5	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-1.2057035254786972	[22]	[17]	-6	hSpCas9	negative selection	11184131
48816603	48816626	X	-	28162770	OCIAML5	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.4565339923763728	[173]	[430]	4	hSpCas9	negative selection	11184132
48822651	48822674	X	-	28162770	OCIAML5	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	1.1698482055644437	[97]	[397]	8	hSpCas9	negative selection	11184133
48802945	48802968	X	+	28162770	EOL1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.2195186992815613	[550]	[337]	2	hSpCas9	negative selection	11353490
48822686	48822709	X	-	28162770	EOL1	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	0.37805941866401405	[221]	[151]	3	hSpCas9	negative selection	11353491
48815894	48815917	X	+	28162770	EOL1	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.9022326490747196	[485]	[136]	-6	hSpCas9	negative selection	11353492
48822673	48822696	X	-	28162770	EOL1	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.6300410801071026	[422]	[71]	-7	hSpCas9	negative selection	11353493
48802762	48802785	X	-	28162770	EOL1	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	-1.1438392034097156	[863]	[205]	-6	hSpCas9	negative selection	11353494
48808116	48808139	X	+	28162770	EOL1	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.8778545361224928	[470]	[455]	7	hSpCas9	negative selection	11353495
48814511	48814534	X	-	28162770	EOL1	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	1.725945238331739	[415]	[724]	9	hSpCas9	negative selection	11353496
48814840	48814863	X	-	28162770	EOL1	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.3510866710428928	[45]	[18]	-3	hSpCas9	negative selection	11353497
48816603	48816626	X	-	28162770	EOL1	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.5694528127479729	[329]	[257]	5	hSpCas9	negative selection	11353498
48822651	48822674	X	-	28162770	EOL1	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.08773055820790221	[235]	[116]	0	hSpCas9	negative selection	11353499
48802945	48802968	X	+	28162770	MOLM13	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.1215646323497495	[409]	[644]	8	hSpCas9	negative selection	11522856
48822686	48822709	X	-	28162770	MOLM13	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.006791064161666804	[213]	[153]	0	hSpCas9	negative selection	11522857
48815894	48815917	X	+	28162770	MOLM13	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.78307219198864	[475]	[199]	-4	hSpCas9	negative selection	11522858
48822673	48822696	X	-	28162770	MOLM13	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-4.011579990329263	[289]	[12]	-9	hSpCas9	negative selection	11522859
48802762	48802785	X	-	28162770	MOLM13	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.09906031168818807	[593]	[459]	0	hSpCas9	negative selection	11522860
48808116	48808139	X	+	28162770	MOLM13	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.45377978212914305	[410]	[406]	3	hSpCas9	negative selection	11522861
48814511	48814534	X	-	28162770	MOLM13	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.8187044378690961	[355]	[453]	6	hSpCas9	negative selection	11522862
48814840	48814863	X	-	28162770	MOLM13	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.14596128665721642	[19]	[15]	1	hSpCas9	negative selection	11522863
48816603	48816626	X	-	28162770	MOLM13	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.1704363447753025	[357]	[229]	-1	hSpCas9	negative selection	11522864
48822651	48822674	X	-	28162770	MOLM13	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.4575843731528404	[280]	[278]	3	hSpCas9	negative selection	11522865
48802945	48802968	X	+	28162770	HEL	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.4402459681016138	[335]	[291]	3	hSpCas9	negative selection	11692222
48822686	48822709	X	-	28162770	HEL	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.3381523450519385	[224]	[113]	-2	hSpCas9	negative selection	11692223
48815894	48815917	X	+	28162770	HEL	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.0784280523191103	[332]	[100]	-6	hSpCas9	negative selection	11692224
48822673	48822696	X	-	28162770	HEL	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-4.843761029835111	[268]	[5]	-9	hSpCas9	negative selection	11692225
48802762	48802785	X	-	28162770	HEL	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.6269715161420404	[551]	[545]	5	hSpCas9	negative selection	11692226
48808116	48808139	X	+	28162770	HEL	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.4254533010969979	[328]	[282]	3	hSpCas9	negative selection	11692227
48814511	48814534	X	-	28162770	HEL	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.3626309128076215	[356]	[293]	3	hSpCas9	negative selection	11692228
48814840	48814863	X	-	28162770	HEL	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.14797414025077904	[30]	[21]	1	hSpCas9	negative selection	11692229
48816603	48816626	X	-	28162770	HEL	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.626708722181408	[361]	[357]	5	hSpCas9	negative selection	11692230
48822651	48822674	X	-	28162770	HEL	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.07821888596545729	[238]	[144]	0	hSpCas9	negative selection	11692231
48802945	48802968	X	+	28162770	MV411	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.1691704939855121	[302]	[286]	1	hSpCas9	negative selection	11861588
48822686	48822709	X	-	28162770	MV411	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.29618415455748154	[171]	[117]	-2	hSpCas9	negative selection	11861589
48815894	48815917	X	+	28162770	MV411	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-0.39610667120159126	[288]	[184]	-3	hSpCas9	negative selection	11861590
48822673	48822696	X	-	28162770	MV411	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.1561408331210048	[208]	[78]	-6	hSpCas9	negative selection	11861591
48802762	48802785	X	-	28162770	MV411	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.07235084422468385	[419]	[371]	0	hSpCas9	negative selection	11861592
48808116	48808139	X	+	28162770	MV411	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	1.259262986179565	[242]	[489]	9	hSpCas9	negative selection	11861593
48814511	48814534	X	-	28162770	MV411	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.6553576451924681	[253]	[336]	6	hSpCas9	negative selection	11861594
48814840	48814863	X	-	28162770	MV411	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-1.415527461939654	[18]	[5]	-7	hSpCas9	negative selection	11861595
48816603	48816626	X	-	28162770	MV411	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.08899011379970223	[249]	[197]	0	hSpCas9	negative selection	11861596
48822651	48822674	X	-	28162770	MV411	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.33752494993838106	[176]	[117]	-3	hSpCas9	negative selection	11861597
48802945	48802968	X	+	28162770	MONOMAC1	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	1.1445200545767413	[145]	[369]	8	hSpCas9	negative selection	12030954
48822686	48822709	X	-	28162770	MONOMAC1	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	1.8457128003997834	[132]	[547]	9	hSpCas9	negative selection	12030955
48815894	48815917	X	+	28162770	MONOMAC1	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	0.8771449660961491	[198]	[418]	7	hSpCas9	negative selection	12030956
48822673	48822696	X	-	28162770	MONOMAC1	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-2.509919802343909	[158]	[31]	-9	hSpCas9	negative selection	12030957
48802762	48802785	X	-	28162770	MONOMAC1	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	0.4445091820279701	[324]	[506]	4	hSpCas9	negative selection	12030958
48808116	48808139	X	+	28162770	MONOMAC1	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	0.8656080899294423	[168]	[352]	7	hSpCas9	negative selection	12030959
48814511	48814534	X	-	28162770	MONOMAC1	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.4450695607652111	[197]	[308]	4	hSpCas9	negative selection	12030960
48814840	48814863	X	-	28162770	MONOMAC1	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.2623947715777435	[7]	[10]	2	hSpCas9	negative selection	12030961
48816603	48816626	X	-	28162770	MONOMAC1	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.46073096159799526	[160]	[253]	4	hSpCas9	negative selection	12030962
48822651	48822674	X	-	28162770	MONOMAC1	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	0.14610773373750444	[107]	[136]	1	hSpCas9	negative selection	12030963
48802945	48802968	X	+	28162770	OCIAML2	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.16680009537313045	[62]	[391]	1	hSpCas9	negative selection	12200320
48822686	48822709	X	-	28162770	OCIAML2	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.4200037521721933	[27]	[115]	-3	hSpCas9	negative selection	12200321
48815894	48815917	X	+	28162770	OCIAML2	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.026327731458123	[60]	[165]	-6	hSpCas9	negative selection	12200322
48822673	48822696	X	-	28162770	OCIAML2	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.4161820412197847	[38]	[80]	-7	hSpCas9	negative selection	12200323
48802762	48802785	X	-	28162770	OCIAML2	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	-0.015528460103596764	[90]	[498]	0	hSpCas9	negative selection	12200324
48808116	48808139	X	+	28162770	OCIAML2	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	1.4201411050030806	[35]	[533]	9	hSpCas9	negative selection	12200325
48814511	48814534	X	-	28162770	OCIAML2	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	1.2324497747716352	[41]	[546]	9	hSpCas9	negative selection	12200326
48814840	48814863	X	-	28162770	OCIAML2	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	0.5293701747578385	[1]	[15]	5	hSpCas9	negative selection	12200327
48816603	48816626	X	-	28162770	OCIAML2	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	0.14234705164859163	[50]	[311]	1	hSpCas9	negative selection	12200328
48822651	48822674	X	-	28162770	OCIAML2	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.025844982569265484	[26]	[146]	0	hSpCas9	negative selection	12200329
48802945	48802968	X	+	28162770	OCIAML3	viability	GAAGAAGCTCGGCCAAGCAATGG	HDAC6	ENSG00000094631	0.5255739754285095	[80]	[351]	5	hSpCas9	negative selection	12369686
48822686	48822709	X	-	28162770	OCIAML3	viability	GGCAGGGTCAGCAGGGGTGGTGG	HDAC6	ENSG00000094631	-0.15862149565351696	[43]	[118]	-1	hSpCas9	negative selection	12369687
48815894	48815917	X	+	28162770	OCIAML3	viability	GGAGAGGGACAACATGGAGGAGG	HDAC6	ENSG00000094631	-1.017219071048707	[58]	[87]	-6	hSpCas9	negative selection	12369688
48822673	48822696	X	-	28162770	OCIAML3	viability	GGGGTGGTGGGTCTCCAAGGAGG	HDAC6	ENSG00000094631	-1.9509421850394386	[72]	[56]	-8	hSpCas9	negative selection	12369689
48802762	48802785	X	-	28162770	OCIAML3	viability	GAAGTGACACTGGAGTCCTGAGG	HDAC6	ENSG00000094631	-0.11254971535686686	[129]	[362]	-1	hSpCas9	negative selection	12369690
48808116	48808139	X	+	28162770	OCIAML3	viability	AACAGAAACACCGCATCCGGAGG	HDAC6	ENSG00000094631	-0.2442005128613643	[81]	[208]	-2	hSpCas9	negative selection	12369691
48814511	48814534	X	-	28162770	OCIAML3	viability	GCCTTGGCCGAAACCTGTGGTGG	HDAC6	ENSG00000094631	0.4315274517829744	[69]	[284]	4	hSpCas9	negative selection	12369692
48814840	48814863	X	-	28162770	OCIAML3	viability	GCAGCCACCAGGACCAGCTGAGG	HDAC6	ENSG00000094631	-0.676469800516136	[8]	[16]	-5	hSpCas9	negative selection	12369693
48816603	48816626	X	-	28162770	OCIAML3	viability	AGAGCACAGCCTCCACCAGGCGG	HDAC6	ENSG00000094631	-0.20169021754540295	[55]	[146]	-1	hSpCas9	negative selection	12369694
48822651	48822674	X	-	28162770	OCIAML3	viability	GGAGCGAGTGCAGGCAGCCATGG	HDAC6	ENSG00000094631	-0.6104957631127323	[43]	[86]	-5	hSpCas9	negative selection	12369695