Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3280
• Symbol: HES1
• Description: hes family bHLH transcription factor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HES1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
194136415	194136438	3	-	26472758	Jiyoye	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	1.452690040758242	[77]	[160]	8	hSpCas9	negative selection	70286
194137940	194137963	3	-	26472758	Jiyoye	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	1.1956712763121615	[21]	[37]	7	hSpCas9	negative selection	70287
194137013	194137036	3	+	26472758	Jiyoye	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	6.407175381505873	[0]	[63]	9	hSpCas9	negative selection	70288
194136966	194136989	3	+	26472758	Jiyoye	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	1.2436766492229938	[27]	[49]	7	hSpCas9	negative selection	70289
194136431	194136454	3	-	26472758	Jiyoye	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.3270050328218901	[332]	[314]	2	hSpCas9	negative selection	70290
194136613	194136636	3	+	26472758	Jiyoye	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.4030942046940562	[353]	[352]	3	hSpCas9	negative selection	70291
194136467	194136490	3	+	26472758	Jiyoye	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.05667813442174	[50]	[79]	7	hSpCas9	negative selection	70292
194136947	194136970	3	+	26472758	Jiyoye	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.425308525677752	[332]	[186]	-3	hSpCas9	negative selection	70293
194137026	194137049	3	+	26472758	Jiyoye	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.0809471491848856	[83]	[66]	0	hSpCas9	negative selection	70294
194137001	194137024	3	+	26472758	Jiyoye	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.3305540999029609	[231]	[219]	2	hSpCas9	negative selection	70295
194136415	194136438	3	-	26472758	KBM7	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	1.1366138798278043	[379,229]	[187,416]	9	hSpCas9	negative selection	261404
194137940	194137963	3	-	26472758	KBM7	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.346686492016836	[98,114]	[68,60]	3	hSpCas9	negative selection	261405
194137013	194137036	3	+	26472758	KBM7	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	-0.0860624534493093	[209,152]	[88,70]	-1	hSpCas9	negative selection	261406
194136966	194136989	3	+	26472758	KBM7	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.8516455624713042	[220,130]	[65,25]	-6	hSpCas9	negative selection	261407
194136431	194136454	3	-	26472758	KBM7	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.7367590896343452	[1653,1524]	[1702,837]	7	hSpCas9	negative selection	261408
194136613	194136636	3	+	26472758	KBM7	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.31177772518111735	[1478,1025]	[852,602]	3	hSpCas9	negative selection	261409
194136467	194136490	3	+	26472758	KBM7	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.1713295096048543	[530,549]	[276,297]	1	hSpCas9	negative selection	261410
194136947	194136970	3	+	26472758	KBM7	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.3113800758225238	[1029,763]	[461,567]	3	hSpCas9	negative selection	261411
194137026	194137049	3	+	26472758	KBM7	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.8338829610230584	[170,235]	[170,176]	8	hSpCas9	negative selection	261412
194137001	194137024	3	+	26472758	KBM7	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.5272493603865849	[855,1024]	[697,599]	6	hSpCas9	negative selection	261413
194136415	194136438	3	-	26472758	Raji	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	1.1524714249021377	[125]	[64]	8	hSpCas9	negative selection	452522
194137940	194137963	3	-	26472758	Raji	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	2.4122381169020204	[16]	[20]	9	hSpCas9	negative selection	452523
194137013	194137036	3	+	26472758	Raji	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	1.1777728632649975	[79]	[41]	8	hSpCas9	negative selection	452524
194136966	194136989	3	+	26472758	Raji	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	2.1365298810331157	[48]	[49]	9	hSpCas9	negative selection	452525
194136431	194136454	3	-	26472758	Raji	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.6549951937404217	[612]	[223]	6	hSpCas9	negative selection	452526
194136613	194136636	3	+	26472758	Raji	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.0405285606173482	[529]	[252]	8	hSpCas9	negative selection	452527
194136467	194136490	3	+	26472758	Raji	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.3096466158775926	[298]	[171]	9	hSpCas9	negative selection	452528
194136947	194136970	3	+	26472758	Raji	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	1.4271405312193348	[398]	[248]	9	hSpCas9	negative selection	452529
194137026	194137049	3	+	26472758	Raji	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.3436178818636779	[162]	[47]	3	hSpCas9	negative selection	452530
194137001	194137024	3	+	26472758	Raji	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.9268112897317787	[407]	[179]	8	hSpCas9	negative selection	452531
194136415	194136438	3	-	26472758	K562	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.9020248404367026	[258]	[116]	-5	hSpCas9	negative selection	643640
194137940	194137963	3	-	26472758	K562	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	-0.49254686649975943	[74]	[44]	-3	hSpCas9	negative selection	643641
194137013	194137036	3	+	26472758	K562	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	1.6458671621973355	[119]	[316]	9	hSpCas9	negative selection	643642
194136966	194136989	3	+	26472758	K562	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	1.6211392953941886	[123]	[321]	9	hSpCas9	negative selection	643643
194136431	194136454	3	-	26472758	K562	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.7377005381662516	[1098]	[1546]	6	hSpCas9	negative selection	643644
194136613	194136636	3	+	26472758	K562	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.9627224619069226	[1135]	[1868]	7	hSpCas9	negative selection	643645
194136467	194136490	3	+	26472758	K562	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.1983223130769929	[476]	[923]	8	hSpCas9	negative selection	643646
194136947	194136970	3	+	26472758	K562	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.8734016409596413	[623]	[964]	7	hSpCas9	negative selection	643647
194137026	194137049	3	+	26472758	K562	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	1.2630825719314827	[191]	[388]	9	hSpCas9	negative selection	643648
194137001	194137024	3	+	26472758	K562	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.591640842717719	[734]	[934]	5	hSpCas9	negative selection	643649
194136434	194136457	3	+	26627737	DLD1	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.35275426877708815	[1432]	[510,461,715]	3	hSpCas9	negative selection	820993
194136436	194136459	3	-	26627737	DLD1	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.2868180571724369	[453]	[214,213,102]	3	hSpCas9	negative selection	820994
194136960	194136983	3	+	26627737	DLD1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.34276961526871774	[535]	[228,167,234]	3	hSpCas9	negative selection	820995
194137729	194137752	3	+	26627737	DLD1	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.557851802849745	[688]	[390,223,329]	5	hSpCas9	negative selection	820996
194137756	194137779	3	-	26627737	DLD1	viability	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.1528698236974877	[842]	[285,327,269]	1	hSpCas9	negative selection	820997
194138189	194138212	3	-	26627737	DLD1	viability	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.20172839992433195	[498]	[126,218,191]	2	hSpCas9	negative selection	820998
194136434	194136457	3	+	26627737	GBM cells	viability after 5 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.44205619991221456	[594]	[451,414]	6	hSpCas9	negative selection	903308
194136436	194136459	3	-	26627737	GBM cells	viability after 5 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.33056797123708165	[271]	[94,136]	-5	hSpCas9	negative selection	903309
194136960	194136983	3	+	26627737	GBM cells	viability after 5 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.09288923880605143	[270]	[155,153]	1	hSpCas9	negative selection	903310
194137729	194137752	3	+	26627737	GBM cells	viability after 5 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.3162764271107734	[464]	[342,277]	5	hSpCas9	negative selection	903311
194137756	194137779	3	-	26627737	GBM cells	viability after 5 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.1794829400119905	[367]	[232,213]	3	hSpCas9	negative selection	903312
194138189	194138212	3	-	26627737	GBM cells	viability after 5 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.4572299353395899	[191]	[79,69]	-6	hSpCas9	negative selection	903313
194136434	194136457	3	+	26627737	GBM cells	viability after 13 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.5898641548829748	[594]	[636,362]	7	hSpCas9	negative selection	985623
194136436	194136459	3	-	26627737	GBM cells	viability after 13 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.7548761985460274	[271]	[103,73]	-7	hSpCas9	negative selection	985624
194136960	194136983	3	+	26627737	GBM cells	viability after 13 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.03018648673940036	[270]	[169,133]	0	hSpCas9	negative selection	985625
194137729	194137752	3	+	26627737	GBM cells	viability after 13 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.19517086679375373	[464]	[327,256]	2	hSpCas9	negative selection	985626
194137756	194137779	3	-	26627737	GBM cells	viability after 13 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.40887000162634224	[367]	[306,230]	5	hSpCas9	negative selection	985627
194138189	194138212	3	-	26627737	GBM cells	viability after 13 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.44505559238550985	[191]	[86,67]	-5	hSpCas9	negative selection	985628
194136434	194136457	3	+	26627737	GBM cells	viability after 21 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.5622735518263848	[594]	[469,483]	6	hSpCas9	negative selection	1067938
194136436	194136459	3	-	26627737	GBM cells	viability after 21 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.9487943703727016	[271]	[86,66]	-7	hSpCas9	negative selection	1067939
194136960	194136983	3	+	26627737	GBM cells	viability after 21 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.36227609886738305	[270]	[194,183]	4	hSpCas9	negative selection	1067940
194137729	194137752	3	+	26627737	GBM cells	viability after 21 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.007578618226961931	[464]	[254,252]	0	hSpCas9	negative selection	1067941
194137756	194137779	3	-	26627737	GBM cells	viability after 21 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.4408301214357506	[367]	[285,257]	4	hSpCas9	negative selection	1067942
194138189	194138212	3	-	26627737	GBM cells	viability after 21 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.13810999025868656	[191]	[107,120]	1	hSpCas9	negative selection	1067943
194136434	194136457	3	+	26627737	RPE1	viability after 9 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.336303714125032	[2956]	[734,730]	-2	hSpCas9	negative selection	1150253
194136436	194136459	3	-	26627737	RPE1	viability after 9 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.2035697199836486	[1285]	[522,386]	1	hSpCas9	negative selection	1150254
194136960	194136983	3	+	26627737	RPE1	viability after 9 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.08448350506275026	[989]	[197,413]	0	hSpCas9	negative selection	1150255
194137729	194137752	3	+	26627737	RPE1	viability after 9 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.14494304610324882	[1205]	[430,399]	1	hSpCas9	negative selection	1150256
194137756	194137779	3	-	26627737	RPE1	viability after 9 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.02709239932827945	[1379]	[365,535]	0	hSpCas9	negative selection	1150257
194138189	194138212	3	-	26627737	RPE1	viability after 9 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.6345557123375305	[377]	[136,243]	4	hSpCas9	negative selection	1150258
194136434	194136457	3	+	26627737	RPE1	viability after 12 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.2459128807026114	[2956]	[548,797]	-2	hSpCas9	negative selection	1232568
194136436	194136459	3	-	26627737	RPE1	viability after 12 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.08819545712124233	[1285]	[376,356]	0	hSpCas9	negative selection	1232569
194136960	194136983	3	+	26627737	RPE1	viability after 12 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.10280645253879508	[989]	[185,312]	0	hSpCas9	negative selection	1232570
194137729	194137752	3	+	26627737	RPE1	viability after 12 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.1163636182641794	[1205]	[358,342]	0	hSpCas9	negative selection	1232571
194137756	194137779	3	-	26627737	RPE1	viability after 12 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.06216811455679716	[1379]	[338,437]	0	hSpCas9	negative selection	1232572
194138189	194138212	3	-	26627737	RPE1	viability after 12 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.9922845144784225	[377]	[236,164]	6	hSpCas9	negative selection	1232573
194136434	194136457	3	+	26627737	RPE1	viability after 15 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.0304380565546567	[2956]	[902,737]	0	hSpCas9	negative selection	1314883
194136436	194136459	3	-	26627737	RPE1	viability after 15 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.42243278294476205	[1285]	[569,407]	2	hSpCas9	negative selection	1314884
194136960	194136983	3	+	26627737	RPE1	viability after 15 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.5638435598034215	[989]	[81,106]	-7	hSpCas9	negative selection	1314885
194137729	194137752	3	+	26627737	RPE1	viability after 15 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.4090658949023225	[1205]	[537,370]	2	hSpCas9	negative selection	1314886
194137756	194137779	3	-	26627737	RPE1	viability after 15 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.44831402293126565	[1379]	[580,485]	3	hSpCas9	negative selection	1314887
194138189	194138212	3	-	26627737	RPE1	viability after 15 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	1.084932944630444	[377]	[292,162]	6	hSpCas9	negative selection	1314888
194136434	194136457	3	+	26627737	RPE1	viability after 18 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.12426089603804535	[2956]	[750,711]	-1	hSpCas9	negative selection	1397198
194136436	194136459	3	-	26627737	RPE1	viability after 18 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.14269369152416977	[1285]	[386,378]	0	hSpCas9	negative selection	1397199
194136960	194136983	3	+	26627737	RPE1	viability after 18 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.8142738390786435	[989]	[120,184]	-5	hSpCas9	negative selection	1397200
194137729	194137752	3	+	26627737	RPE1	viability after 18 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.23735086002053019	[1205]	[336,210]	-1	hSpCas9	negative selection	1397201
194137756	194137779	3	-	26627737	RPE1	viability after 18 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.3070226742301094	[1379]	[321,608]	2	hSpCas9	negative selection	1397202
194138189	194138212	3	-	26627737	RPE1	viability after 18 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	1.2120376445833692	[377]	[303,163]	7	hSpCas9	negative selection	1397203
194136434	194136457	3	+	26627737	HeLa	viability after 8 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.014620297705183916	[1107]	[359,642,407]	0	hSpCas9	negative selection	1479513
194136436	194136459	3	-	26627737	HeLa	viability after 8 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.1565134503908574	[228]	[80,125,118]	1	hSpCas9	negative selection	1479514
194136960	194136983	3	+	26627737	HeLa	viability after 8 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.020882580647945792	[529]	[407,90,222]	0	hSpCas9	negative selection	1479515
194137729	194137752	3	+	26627737	HeLa	viability after 8 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.4000618260285393	[357]	[239,85,291]	3	hSpCas9	negative selection	1479516
194137756	194137779	3	-	26627737	HeLa	viability after 8 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.04761371355054361	[478]	[192,227,219]	0	hSpCas9	negative selection	1479517
194138189	194138212	3	-	26627737	HeLa	viability after 8 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.5887575118137586	[418]	[136,76,150]	-5	hSpCas9	negative selection	1479518
194136434	194136457	3	+	26627737	HeLa	viability after 12 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.06573036891151718	[1107]	[335,338,644]	0	hSpCas9	negative selection	1561828
194136436	194136459	3	-	26627737	HeLa	viability after 12 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	1.0214715805743002	[228]	[140,152,284]	7	hSpCas9	negative selection	1561829
194136960	194136983	3	+	26627737	HeLa	viability after 12 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.9358384299811903	[529]	[189,35,127]	-7	hSpCas9	negative selection	1561830
194137729	194137752	3	+	26627737	HeLa	viability after 12 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.7214479565852145	[357]	[428,160,155]	6	hSpCas9	negative selection	1561831
194137756	194137779	3	-	26627737	HeLa	viability after 12 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.2739442794868421	[478]	[223,244,247]	2	hSpCas9	negative selection	1561832
194138189	194138212	3	-	26627737	HeLa	viability after 12 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.05261474930549615	[418]	[153,114,236]	0	hSpCas9	negative selection	1561833
194136434	194136457	3	+	26627737	HeLa	viability after 15 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.1858628347849789	[1107]	[332,393,468]	-1	hSpCas9	negative selection	1644143
194136436	194136459	3	-	26627737	HeLa	viability after 15 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.5496967695039088	[228]	[136,212,52]	4	hSpCas9	negative selection	1644144
194136960	194136983	3	+	26627737	HeLa	viability after 15 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.046368230657700904	[529]	[192,117,368]	0	hSpCas9	negative selection	1644145
194137729	194137752	3	+	26627737	HeLa	viability after 15 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.1773090010333245	[357]	[186,179,123]	1	hSpCas9	negative selection	1644146
194137756	194137779	3	-	26627737	HeLa	viability after 15 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.32242429464555633	[478]	[272,227,228]	2	hSpCas9	negative selection	1644147
194138189	194138212	3	-	26627737	HeLa	viability after 15 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.9905224770628529	[418]	[76,126,50]	-7	hSpCas9	negative selection	1644148
194136434	194136457	3	+	26627737	HeLa	viability after 18 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.16032752280845708	[1107]	[222,343,468]	-1	hSpCas9	negative selection	1726458
194136436	194136459	3	-	26627737	HeLa	viability after 18 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.5276909989445764	[228]	[88,174,52]	4	hSpCas9	negative selection	1726459
194136960	194136983	3	+	26627737	HeLa	viability after 18 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.05809630982864783	[529]	[131,98,368]	0	hSpCas9	negative selection	1726460
194137729	194137752	3	+	26627737	HeLa	viability after 18 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.14220180591479634	[357]	[116,149,123]	1	hSpCas9	negative selection	1726461
194137756	194137779	3	-	26627737	HeLa	viability after 18 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.35191150837703644	[478]	[187,194,228]	3	hSpCas9	negative selection	1726462
194138189	194138212	3	-	26627737	HeLa	viability after 18 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-1.0025979704932608	[418]	[47,107,50]	-7	hSpCas9	negative selection	1726463
194136434	194136457	3	+	26627737	HCT116	viability after 6 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.13081075387489371	[1705]	[427,143]	0	hSpCas9	negative selection	1808773
194136436	194136459	3	-	26627737	HCT116	viability after 6 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.8559972204716639	[482]	[324,33]	5	hSpCas9	negative selection	1808774
194136960	194136983	3	+	26627737	HCT116	viability after 6 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.8012469210149424	[508]	[297,51]	4	hSpCas9	negative selection	1808775
194137729	194137752	3	+	26627737	HCT116	viability after 6 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	2.682323679365627	[321]	[623,159]	9	hSpCas9	negative selection	1808776
194137756	194137779	3	-	26627737	HCT116	viability after 6 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.07970499604794079	[1644]	[410,152]	0	hSpCas9	negative selection	1808777
194138189	194138212	3	-	26627737	HCT116	viability after 6 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.8984793822171051	[690]	[143,10]	-5	hSpCas9	negative selection	1808778
194136434	194136457	3	+	26627737	HCT116	viability after 8 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.5153097946609699	[935]	[392,236,451]	-6	hSpCas9	negative selection	1891088
194136436	194136459	3	-	26627737	HCT116	viability after 8 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.14646381237806871	[181]	[94,94,81]	-2	hSpCas9	negative selection	1891089
194136960	194136983	3	+	26627737	HCT116	viability after 8 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.3566471524663152	[268]	[169,288,110]	4	hSpCas9	negative selection	1891090
194137729	194137752	3	+	26627737	HCT116	viability after 8 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.2526573558191216	[366]	[253,307,161]	3	hSpCas9	negative selection	1891091
194137756	194137779	3	-	26627737	HCT116	viability after 8 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.08690165334558331	[480]	[288,221,332]	1	hSpCas9	negative selection	1891092
194138189	194138212	3	-	26627737	HCT116	viability after 8 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.06416264811765993	[320]	[158,184,209]	0	hSpCas9	negative selection	1891093
194136434	194136457	3	+	26627737	HCT116	viability after 9 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.7157943141144204	[1705]	[416,166]	-5	hSpCas9	negative selection	1973403
194136436	194136459	3	-	26627737	HCT116	viability after 9 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.5738698368718111	[482]	[258,138]	4	hSpCas9	negative selection	1973404
194136960	194136983	3	+	26627737	HCT116	viability after 9 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	1.1427198324893808	[508]	[179,394]	7	hSpCas9	negative selection	1973405
194137729	194137752	3	+	26627737	HCT116	viability after 9 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	1.2085406188989363	[321]	[377,56]	7	hSpCas9	negative selection	1973406
194137756	194137779	3	-	26627737	HCT116	viability after 9 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.7548655353760081	[1644]	[452,107]	-5	hSpCas9	negative selection	1973407
194138189	194138212	3	-	26627737	HCT116	viability after 9 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.2411687198044285	[690]	[326,131]	1	hSpCas9	negative selection	1973408
194136434	194136457	3	+	26627737	HCT116	viability after 12 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.8185530951611173	[935]	[190,342,311]	-7	hSpCas9	negative selection	2055718
194136436	194136459	3	-	26627737	HCT116	viability after 12 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.4203353518708691	[181]	[138,126,116]	4	hSpCas9	negative selection	2055719
194136960	194136983	3	+	26627737	HCT116	viability after 12 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.2886013079351796	[268]	[143,232,144]	3	hSpCas9	negative selection	2055720
194137729	194137752	3	+	26627737	HCT116	viability after 12 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.39939120648360654	[366]	[186,333,249]	4	hSpCas9	negative selection	2055721
194137756	194137779	3	-	26627737	HCT116	viability after 12 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.01872698748456647	[480]	[185,243,323]	0	hSpCas9	negative selection	2055722
194138189	194138212	3	-	26627737	HCT116	viability after 12 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.6925287057520172	[320]	[53,121,141]	-6	hSpCas9	negative selection	2055723
194136434	194136457	3	+	26627737	HCT116	viability after 15 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.4557274772923161	[935]	[368,325,476]	-5	hSpCas9	negative selection	2138033
194136436	194136459	3	-	26627737	HCT116	viability after 15 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.18650568712912363	[181]	[128,187,41]	2	hSpCas9	negative selection	2138034
194136960	194136983	3	+	26627737	HCT116	viability after 15 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.24530320413766554	[268]	[179,187,180]	2	hSpCas9	negative selection	2138035
194137729	194137752	3	+	26627737	HCT116	viability after 15 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.033698106737971134	[366]	[218,242,185]	0	hSpCas9	negative selection	2138036
194137756	194137779	3	-	26627737	HCT116	viability after 15 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.04437125549751075	[480]	[363,196,302]	0	hSpCas9	negative selection	2138037
194138189	194138212	3	-	26627737	HCT116	viability after 15 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.5365937381244635	[320]	[134,100,145]	-5	hSpCas9	negative selection	2138038
194136434	194136457	3	+	26627737	HCT116	viability after 18 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.22713718990810783	[935]	[261,452,442]	-2	hSpCas9	negative selection	2220348
194136436	194136459	3	-	26627737	HCT116	viability after 18 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.6559253232223892	[181]	[234,123,53]	5	hSpCas9	negative selection	2220349
194136960	194136983	3	+	26627737	HCT116	viability after 18 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.14810493198018468	[268]	[80,129,225]	1	hSpCas9	negative selection	2220350
194137729	194137752	3	+	26627737	HCT116	viability after 18 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.310714082727827	[366]	[226,295,127]	2	hSpCas9	negative selection	2220351
194137756	194137779	3	-	26627737	HCT116	viability after 18 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.004029060055088851	[480]	[309,119,274]	0	hSpCas9	negative selection	2220352
194138189	194138212	3	-	26627737	HCT116	viability after 18 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.46629576617656476	[320]	[147,88,100]	-4	hSpCas9	negative selection	2220353
194136431	194136454	3	-	24336569	HL60	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.820653744672703	[544]	[2036]	6	hSpCas9	negative selection	2269444
194136436	194136459	3	-	24336569	HL60	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.4435336111023177	[654]	[1884]	4	hSpCas9	negative selection	2269445
194136453	194136476	3	-	24336569	HL60	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	0.7080520155910194	[185]	[642]	6	hSpCas9	negative selection	2269446
194136462	194136485	3	-	24336569	HL60	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.09983049398678912	[645]	[1464]	1	hSpCas9	negative selection	2269447
194136467	194136490	3	+	24336569	HL60	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.9715399363593518	[647]	[2688]	7	hSpCas9	negative selection	2269448
194136613	194136636	3	+	24336569	HL60	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.32271240601818074	[149]	[396]	3	hSpCas9	negative selection	2269449
194136947	194136970	3	+	24336569	HL60	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.5158669247746711	[274]	[406]	-5	hSpCas9	negative selection	2269450
194136960	194136983	3	+	24336569	HL60	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.7970560440025354	[334]	[203]	-9	hSpCas9	negative selection	2269451
194136966	194136989	3	+	24336569	HL60	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.06673576347834165	[535]	[1082]	0	hSpCas9	negative selection	2269452
194136974	194136997	3	-	24336569	HL60	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	0.4952544059973514	[116]	[348]	4	hSpCas9	negative selection	2269453
194136431	194136454	3	-	24336569	KBM7	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.1234709973170196	[520]	[1547]	1	hSpCas9	negative selection	2336621
194136436	194136459	3	-	24336569	KBM7	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.20275931302429762	[603]	[1895]	2	hSpCas9	negative selection	2336622
194136453	194136476	3	-	24336569	KBM7	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	0.9904070278020565	[190]	[1034]	8	hSpCas9	negative selection	2336623
194136462	194136485	3	-	24336569	KBM7	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.8127611001156482	[334]	[1604]	7	hSpCas9	negative selection	2336624
194136467	194136490	3	+	24336569	KBM7	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	-0.060336518570715425	[772]	[2021]	0	hSpCas9	negative selection	2336625
194136613	194136636	3	+	24336569	KBM7	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	-0.42322933513313377	[469]	[955]	-3	hSpCas9	negative selection	2336626
194136947	194136970	3	+	24336569	KBM7	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.17194475393545527	[132]	[321]	-1	hSpCas9	negative selection	2336627
194136960	194136983	3	+	24336569	KBM7	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.06906757329515267	[129]	[337]	0	hSpCas9	negative selection	2336628
194136966	194136989	3	+	24336569	KBM7	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.26178778964754906	[421]	[959]	-2	hSpCas9	negative selection	2336629
194136974	194136997	3	-	24336569	KBM7	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	-0.23105378224443096	[175]	[408]	-2	hSpCas9	negative selection	2336630
194136947	194136970	3	+	27260157	DLD1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.380061268048572	[]	[]	4	hSpCas9	negative selection	2574450
194137729	194137752	3	+	27260157	DLD1	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.700606110233945	[]	[]	-5	hSpCas9	negative selection	2576681
194137001	194137024	3	+	27260157	DLD1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.57148425169004	[]	[]	8	hSpCas9	negative selection	2576971
194137690	194137713	3	+	27260157	DLD1	viability	GAGCACAGACCCAAGTGTGCTGG	HES1	ENSG00000114315	-0.39319896031602	[]	[]	-3	hSpCas9	negative selection	2581327
194136462	194136485	3	-	27260157	DLD1	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.808708396685536	[]	[]	9	hSpCas9	negative selection	2581543
194136467	194136490	3	+	27260157	DLD1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.508068203147164	[]	[]	8	hSpCas9	negative selection	2586893
194137756	194137779	3	+	27260157	DLD1	viability	CCGCTTCCTGTCCACGTGCGAGG	HES1	ENSG00000114315	0.41330404579864	[]	[]	4	hSpCas9	negative selection	2587377
194136436	194136459	3	-	27260157	DLD1	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.288505817987817	[]	[]	-2	hSpCas9	negative selection	2609718
194136453	194136476	3	-	27260157	DLD1	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	-0.479170487975694	[]	[]	-4	hSpCas9	negative selection	2614676
194136960	194136983	3	+	27260157	DLD1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.321685710158823	[]	[]	4	hSpCas9	negative selection	2616866
194137020	194137043	3	-	27260157	DLD1	viability	TCTGCGCCCGCTGCAGGTTCCGG	HES1	ENSG00000114315	-0.19003329009555	[]	[]	-1	hSpCas9	negative selection	2620875
194136430	194136453	3	-	27260157	DLD1	viability	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-1.11415237228514	[]	[]	-7	hSpCas9	negative selection	2622011
194136966	194136989	3	+	27260157	DLD1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.278563819644039	[]	[]	-2	hSpCas9	negative selection	2640735
194137720	194137743	3	-	27260157	DLD1	viability	TGCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.416343471829565	[]	[]	7	hSpCas9	negative selection	2641198
194136974	194136997	3	-	27260157	DLD1	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	1.46593023053761	[]	[]	9	hSpCas9	negative selection	2645206
194136613	194136636	3	+	27260157	DLD1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	-0.190728809404871	[]	[]	-1	hSpCas9	negative selection	2645687
194137755	194137778	3	-	27260157	DLD1	viability	CTCGCACGTGGACAGGAAGCGGG	HES1	ENSG00000114315	0.455921852362384	[]	[]	7	hSpCas9	negative selection	2646947
194137013	194137036	3	+	27260157	DLD1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.0665148029861875	[]	[]	3	hSpCas9	negative selection	2647000
194136947	194136970	3	+	27260157	HT1080	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.162868005968135	[]	[]	0	hSpCas9	negative selection	2650580
194137729	194137752	3	+	27260157	HT1080	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.0432886761930118	[]	[]	0	hSpCas9	negative selection	2652811
194137001	194137024	3	+	27260157	HT1080	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.181280401542735	[]	[]	1	hSpCas9	negative selection	2653101
194137690	194137713	3	+	27260157	HT1080	viability	GAGCACAGACCCAAGTGTGCTGG	HES1	ENSG00000114315	-0.0142816364549131	[]	[]	0	hSpCas9	negative selection	2657457
194136462	194136485	3	-	27260157	HT1080	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.513989337378982	[]	[]	4	hSpCas9	negative selection	2657673
194136467	194136490	3	+	27260157	HT1080	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.943936292478295	[]	[]	7	hSpCas9	negative selection	2663023
194137756	194137779	3	+	27260157	HT1080	viability	CCGCTTCCTGTCCACGTGCGAGG	HES1	ENSG00000114315	0.448679677904843	[]	[]	4	hSpCas9	negative selection	2663507
194136436	194136459	3	-	27260157	HT1080	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.0156955236505494	[]	[]	0	hSpCas9	negative selection	2685848
194136453	194136476	3	-	27260157	HT1080	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	0.524090755437344	[]	[]	4	hSpCas9	negative selection	2690806
194136960	194136983	3	+	27260157	HT1080	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.618624979254913	[]	[]	-8	hSpCas9	negative selection	2692996
194137020	194137043	3	-	27260157	HT1080	viability	TCTGCGCCCGCTGCAGGTTCCGG	HES1	ENSG00000114315	-1.13998367662817	[]	[]	-8	hSpCas9	negative selection	2697005
194136430	194136453	3	-	27260157	HT1080	viability	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	0.0222480735247882	[]	[]	0	hSpCas9	negative selection	2698141
194136966	194136989	3	+	27260157	HT1080	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.571921819842309	[]	[]	5	hSpCas9	negative selection	2716865
194137720	194137743	3	-	27260157	HT1080	viability	TGCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-0.00964314018889081	[]	[]	0	hSpCas9	negative selection	2717328
194136974	194136997	3	-	27260157	HT1080	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	0.109307876174957	[]	[]	1	hSpCas9	negative selection	2721336
194136613	194136636	3	+	27260157	HT1080	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.869144693482836	[]	[]	7	hSpCas9	negative selection	2721817
194137755	194137778	3	-	27260157	HT1080	viability	CTCGCACGTGGACAGGAAGCGGG	HES1	ENSG00000114315	-0.985621794717018	[]	[]	-8	hSpCas9	negative selection	2723077
194137013	194137036	3	+	27260157	HT1080	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.440871652611462	[]	[]	4	hSpCas9	negative selection	2723130
194136947	194136970	3	+	27260157	MKN45	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.353231300015156	[]	[]	-1	hSpCas9	negative selection	2726710
194137729	194137752	3	+	27260157	MKN45	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.280277869128662	[]	[]	-1	hSpCas9	negative selection	2728941
194137001	194137024	3	+	27260157	MKN45	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.422286732745818	[]	[]	6	hSpCas9	negative selection	2729231
194137690	194137713	3	+	27260157	MKN45	viability	GAGCACAGACCCAAGTGTGCTGG	HES1	ENSG00000114315	1.45536727593941	[]	[]	9	hSpCas9	negative selection	2733587
194136462	194136485	3	-	27260157	MKN45	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	1.04872625399588	[]	[]	8	hSpCas9	negative selection	2733803
194136467	194136490	3	+	27260157	MKN45	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.65155403667856	[]	[]	9	hSpCas9	negative selection	2739153
194137756	194137779	3	+	27260157	MKN45	viability	CCGCTTCCTGTCCACGTGCGAGG	HES1	ENSG00000114315	0.489745795134349	[]	[]	6	hSpCas9	negative selection	2739637
194136436	194136459	3	-	27260157	MKN45	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.144834903136023	[]	[]	5	hSpCas9	negative selection	2761978
194136453	194136476	3	-	27260157	MKN45	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	0.249786096063522	[]	[]	5	hSpCas9	negative selection	2766936
194136960	194136983	3	+	27260157	MKN45	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.63666800670368	[]	[]	7	hSpCas9	negative selection	2769126
194137020	194137043	3	-	27260157	MKN45	viability	TCTGCGCCCGCTGCAGGTTCCGG	HES1	ENSG00000114315	-0.460973578678098	[]	[]	-6	hSpCas9	negative selection	2773135
194136430	194136453	3	-	27260157	MKN45	viability	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-0.0199215895938436	[]	[]	0	hSpCas9	negative selection	2774271
194136966	194136989	3	+	27260157	MKN45	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.109325161407183	[]	[]	0	hSpCas9	negative selection	2792995
194137720	194137743	3	-	27260157	MKN45	viability	TGCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.625793788462575	[]	[]	7	hSpCas9	negative selection	2793458
194136974	194136997	3	-	27260157	MKN45	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	0.865449320544952	[]	[]	8	hSpCas9	negative selection	2797466
194136613	194136636	3	+	27260157	MKN45	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.776515417487647	[]	[]	7	hSpCas9	negative selection	2797947
194137755	194137778	3	-	27260157	MKN45	viability	CTCGCACGTGGACAGGAAGCGGG	HES1	ENSG00000114315	-0.636271648152437	[]	[]	-6	hSpCas9	negative selection	2799207
194137013	194137036	3	+	27260157	MKN45	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.410901721384549	[]	[]	6	hSpCas9	negative selection	2799260
194136947	194136970	3	+	27260157	RKO	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.108437484915483	[]	[]	0	hSpCas9	negative selection	2802840
194137729	194137752	3	+	27260157	RKO	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.371446646091817	[]	[]	2	hSpCas9	negative selection	2805071
194137001	194137024	3	+	27260157	RKO	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.457350793704181	[]	[]	2	hSpCas9	negative selection	2805361
194137690	194137713	3	+	27260157	RKO	viability	GAGCACAGACCCAAGTGTGCTGG	HES1	ENSG00000114315	0.997370240922437	[]	[]	9	hSpCas9	negative selection	2809717
194136462	194136485	3	-	27260157	RKO	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.430661044970845	[]	[]	2	hSpCas9	negative selection	2809933
194136467	194136490	3	+	27260157	RKO	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.08533967003317	[]	[]	9	hSpCas9	negative selection	2815283
194137756	194137779	3	+	27260157	RKO	viability	CCGCTTCCTGTCCACGTGCGAGG	HES1	ENSG00000114315	0.0433656327065308	[]	[]	0	hSpCas9	negative selection	2815767
194136436	194136459	3	-	27260157	RKO	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.0134385113942199	[]	[]	0	hSpCas9	negative selection	2838108
194136453	194136476	3	-	27260157	RKO	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	-0.49210032767355	[]	[]	-6	hSpCas9	negative selection	2843066
194136960	194136983	3	+	27260157	RKO	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.339949078435581	[]	[]	1	hSpCas9	negative selection	2845256
194137020	194137043	3	-	27260157	RKO	viability	TCTGCGCCCGCTGCAGGTTCCGG	HES1	ENSG00000114315	0.039685118494638	[]	[]	0	hSpCas9	negative selection	2849265
194136430	194136453	3	-	27260157	RKO	viability	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-0.242865445482946	[]	[]	-1	hSpCas9	negative selection	2850401
194136966	194136989	3	+	27260157	RKO	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	1.176587425467	[]	[]	9	hSpCas9	negative selection	2869125
194137720	194137743	3	-	27260157	RKO	viability	TGCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.914623227101484	[]	[]	8	hSpCas9	negative selection	2869588
194136974	194136997	3	-	27260157	RKO	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	-0.136933949279375	[]	[]	0	hSpCas9	negative selection	2873596
194136613	194136636	3	+	27260157	RKO	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.942390158651805	[]	[]	8	hSpCas9	negative selection	2874077
194137755	194137778	3	-	27260157	RKO	viability	CTCGCACGTGGACAGGAAGCGGG	HES1	ENSG00000114315	-0.749120847209223	[]	[]	-7	hSpCas9	negative selection	2875337
194137013	194137036	3	+	27260157	RKO	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.843526585860572	[]	[]	8	hSpCas9	negative selection	2875390
194136947	194136970	3	+	27260157	SF268	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.507638963243551	[]	[]	-4	hSpCas9	negative selection	2878970
194137729	194137752	3	+	27260157	SF268	viability	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.67584052515161	[]	[]	8	hSpCas9	negative selection	2881201
194137001	194137024	3	+	27260157	SF268	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.623532761615816	[]	[]	8	hSpCas9	negative selection	2881491
194137690	194137713	3	+	27260157	SF268	viability	GAGCACAGACCCAAGTGTGCTGG	HES1	ENSG00000114315	0.918885761794004	[]	[]	9	hSpCas9	negative selection	2885847
194136462	194136485	3	-	27260157	SF268	viability	CTGTGCTCAGATGCTGTCTTTGG	HES1	ENSG00000114315	0.67665254772027	[]	[]	8	hSpCas9	negative selection	2886063
194136467	194136490	3	+	27260157	SF268	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.833352287101375	[]	[]	9	hSpCas9	negative selection	2891413
194137756	194137779	3	+	27260157	SF268	viability	CCGCTTCCTGTCCACGTGCGAGG	HES1	ENSG00000114315	0.0467559796831439	[]	[]	0	hSpCas9	negative selection	2891897
194136436	194136459	3	-	27260157	SF268	viability	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.356300502605863	[]	[]	4	hSpCas9	negative selection	2914238
194136453	194136476	3	-	27260157	SF268	viability	GATGCTGTCTTTGGTTTATCCGG	HES1	ENSG00000114315	0.322683053713454	[]	[]	4	hSpCas9	negative selection	2919196
194136960	194136983	3	+	27260157	SF268	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.447482471287036	[]	[]	7	hSpCas9	negative selection	2921386
194137020	194137043	3	-	27260157	SF268	viability	TCTGCGCCCGCTGCAGGTTCCGG	HES1	ENSG00000114315	0.276453748289536	[]	[]	4	hSpCas9	negative selection	2925395
194136430	194136453	3	-	27260157	SF268	viability	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	0.355192904171046	[]	[]	4	hSpCas9	negative selection	2926531
194136966	194136989	3	+	27260157	SF268	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.247030321554418	[]	[]	-2	hSpCas9	negative selection	2945255
194137720	194137743	3	-	27260157	SF268	viability	TGCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.755266743488018	[]	[]	8	hSpCas9	negative selection	2945718
194136974	194136997	3	-	27260157	SF268	viability	AATGTCCGCCTTCTCCAGCTTGG	HES1	ENSG00000114315	-0.383323989230321	[]	[]	-3	hSpCas9	negative selection	2949726
194136613	194136636	3	+	27260157	SF268	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.865589432494803	[]	[]	9	hSpCas9	negative selection	2950207
194137755	194137778	3	-	27260157	SF268	viability	CTCGCACGTGGACAGGAAGCGGG	HES1	ENSG00000114315	0.101848786007769	[]	[]	0	hSpCas9	negative selection	2951467
194137013	194137036	3	+	27260157	SF268	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	-0.0552260544143654	[]	[]	0	hSpCas9	negative selection	2951520
194137730	194137753	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.3804252699641624	[3,3]	[2,1]	-5	hSpCas9	positive selection	2993086
194136402	194136425	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-1.569713862568779	[1,3]	[0,0]	-9	hSpCas9	positive selection	2993087
194137693	194137716	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	-0.6184423013232903	[2,2]	[1,0]	-7	hSpCas9	positive selection	2993088
194136430	194136453	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-0.19917339408950704	[3,3]	[3,1]	-3	hSpCas9	positive selection	2993089
194137730	194137753	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.6251776858969296	[3,3]	[2,0]	-8	hSpCas9	positive selection	3060944
194136402	194136425	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.08744679289342705	[1,1]	[2,0]	-1	hSpCas9	positive selection	3060945
194137693	194137716	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	-0.365272162898283	[2,2]	[2,0]	-5	hSpCas9	positive selection	3060946
194136430	194136453	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-0.1317377470419628	[3,3]	[1,2]	-2	hSpCas9	positive selection	3060947
194137001	194137024		+	24336571	A375	resistance to PLX after 7 days	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.2094975312375001	[12,11]	[15,12]	6	hSpCas9	positive selection	3118833
194137026	194137049		-	24336571	A375	resistance to PLX after 7 days	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.2618457756838501	[10,9]	[11,13]	7	hSpCas9	positive selection	3118834
194137026	194137049		+	24336571	A375	resistance to PLX after 7 days	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.3237563199483722	[2,2]	[4,2]	8	hSpCas9	positive selection	3118835
194136613	194136636		+	24336571	A375	resistance to PLX after 7 days	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.11398301996983906	[9,8]	[9,10]	4	hSpCas9	positive selection	3118836
194137001	194137024		+	24336571	A375	resistance to PLX after 14 days	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.4518063777628416	[12,13]	[4,3]	-5	hSpCas9	positive selection	3176626
194137026	194137049		-	24336571	A375	resistance to PLX after 14 days	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.5923598433245719	[13,9]	[5,9]	5	hSpCas9	positive selection	3176627
194137026	194137049		+	24336571	A375	resistance to PLX after 14 days	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.6134463929202087	[1,4]	[1,1]	5	hSpCas9	positive selection	3176628
194136613	194136636		+	24336571	A375	resistance to PLX after 14 days	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.0286814612425614	[12,9]	[10,9]	7	hSpCas9	positive selection	3176629
194137001	194137024		+	24336571	A375	viability after 7 days	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.13141675210089843	[13]	[12,11]	-2	hSpCas9	negative selection	3234419
194137026	194137049		-	24336571	A375	viability after 7 days	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	-0.5485266409059074	[16]	[10,9]	-7	hSpCas9	negative selection	3234420
194137026	194137049		+	24336571	A375	viability after 7 days	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-0.09273872033337938	[3]	[2,2]	-1	hSpCas9	negative selection	3234421
194136613	194136636		+	24336571	A375	viability after 7 days	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	-0.09964320211907546	[10]	[9,8]	-1	hSpCas9	negative selection	3234422
194137001	194137024		+	24336571	A375	viability after 14 days	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.007237233411293162	[13]	[12,13]	0	hSpCas9	negative selection	3292212
194137026	194137049		-	24336571	A375	viability after 14 days	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	-0.38828471250812935	[16]	[13,9]	-4	hSpCas9	negative selection	3292213
194137026	194137049		+	24336571	A375	viability after 14 days	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.06053649582754317	[3]	[1,4]	0	hSpCas9	negative selection	3292214
194136613	194136636		+	24336571	A375	viability after 14 days	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.13917811402155542	[10]	[12,9]	1	hSpCas9	negative selection	3292215
194138193	194138216	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	1.2691613478828048	[59,66]	[0,0]	5	hSpCas9	positive selection	3353272
194137782	194137805	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	0.9458078996364034	[67,90]	[0,0]	4	hSpCas9	positive selection	3353273
194137026	194137049	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.08661564230598129	[311,263]	[2,0]	0	hSpCas9	positive selection	3353274
194136401	194136424	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.01892147212075612	[150,150]	[0,0]	0	hSpCas9	positive selection	3372466
194136960	194136983	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.02850752094995433	[149,149]	[0,0]	0	hSpCas9	positive selection	3372467
194136434	194136457	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.08252379143878974	[323,323]	[1,1]	0	hSpCas9	positive selection	3372468
194137729	194137752	3	+	26780180	HT29	viability (Avana library 4 designs)	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	3.24079995535901	[]	[]	8	hSpCas9	negative selection	3430347
194136401	194136424	3	+	26780180	HT29	viability (Avana library 4 designs)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	2.63833318640838	[]	[]	8	hSpCas9	negative selection	3430348
194137692	194137715	3	+	26780180	HT29	viability (Avana library 4 designs)	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	1.11545281839768	[]	[]	4	hSpCas9	negative selection	3430349
194136430	194136453	3	-	26780180	HT29	viability (Avana library 4 designs)	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	2.43149287503231	[]	[]	8	hSpCas9	negative selection	3430350
194137729	194137752	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	6.03882618698957	[]	[]	9	hSpCas9	negative selection	3515463
194137692	194137715	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	2.48286057631124	[]	[]	3	hSpCas9	negative selection	3515464
194136430	194136453	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	3.66139789880922	[]	[]	6	hSpCas9	negative selection	3515465
194136401	194136424	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	3.93318286682994	[]	[]	6	hSpCas9	negative selection	3515466
194136947	194136970	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	3.1628686195809	[]	[]	5	hSpCas9	negative selection	3515467
194136415	194136438	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	6.16055584613208	[]	[]	9	hSpCas9	negative selection	3515468
194137729	194137752	3	+	26780180	A375	viability (Avana lentiGuide)	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	2.27049527427512	[]	[]	2	hSpCas9	negative selection	3624122
194137692	194137715	3	+	26780180	A375	viability (Avana lentiGuide)	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	1.0145632598787	[]	[]	1	hSpCas9	negative selection	3624123
194136430	194136453	3	-	26780180	A375	viability (Avana lentiGuide)	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	7.44791631098231	[]	[]	6	hSpCas9	negative selection	3624124
194136401	194136424	3	+	26780180	A375	viability (Avana lentiGuide)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-1.58678550916102	[]	[]	-3	hSpCas9	negative selection	3624125
194136947	194136970	3	+	26780180	A375	viability (Avana lentiGuide)	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	1.33440796029409	[]	[]	1	hSpCas9	negative selection	3624126
194136415	194136438	3	-	26780180	A375	viability (Avana lentiGuide)	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	3.63947612713442	[]	[]	3	hSpCas9	negative selection	3624127
194137729	194137752	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.2336058381236929	[6]	[7,6]	6	hSpCas9	positive selection	3732781
194137692	194137715	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	0.2697222319699719	[4]	[5,5]	7	hSpCas9	positive selection	3732782
194136430	194136453	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	0.1561966110249609	[4]	[6,4]	4	hSpCas9	positive selection	3732783
194136401	194136424	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.2009068825333453	[4]	[5,5]	5	hSpCas9	positive selection	3732784
194136947	194136970	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.21600641596390519	[5]	[7,6]	6	hSpCas9	positive selection	3732785
194136415	194136438	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.43621412769655143	[4]	[5,6]	9	hSpCas9	positive selection	3732786
194137729	194137752	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.15713582560763964	[6]	[6,5]	3	hSpCas9	positive selection	3841388
194137692	194137715	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGACCCAAGTGTGCTGGGG	HES1	ENSG00000114315	-0.39911769024535954	[4]	[2,1]	-5	hSpCas9	positive selection	3841389
194136430	194136453	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCGTGTTGACACTGGCTGGGG	HES1	ENSG00000114315	-0.49562466010873973	[5]	[1,5]	-6	hSpCas9	positive selection	3841390
194136401	194136424	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.1504509407388846	[4]	[5,3]	3	hSpCas9	positive selection	3841391
194136947	194136970	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.12453593988950584	[6]	[5,6]	3	hSpCas9	positive selection	3841392
194136415	194136438	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-1.0489347669451354	[4]	[0,2]	-8	hSpCas9	positive selection	3841393
194136434	194136457	3	+	26780180	A375	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	1.11734881612207	[]	[]	5	hSpCas9	negative selection	3947455
194137026	194137049	3	-	26780180	A375	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.879186674995891	[]	[]	3	hSpCas9	negative selection	3947456
194138193	194138216	3	+	26780180	A375	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.606764882851836	[]	[]	2	hSpCas9	negative selection	3947457
194136401	194136424	3	+	26780180	A375	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	1.16049028608135	[]	[]	6	hSpCas9	negative selection	3947458
194136960	194136983	3	+	26780180	A375	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	1.49871538682698	[]	[]	8	hSpCas9	negative selection	3947459
194137782	194137805	3	+	26780180	A375	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	1.13346632238512	[]	[]	6	hSpCas9	negative selection	3947460
194136434	194136457	3	+	26780180	HT29	viability (GeCKOv2 library)	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	2.59666324977035	[]	[]	9	hSpCas9	negative selection	4055421
194137026	194137049	3	-	26780180	HT29	viability (GeCKOv2 library)	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	1.97692068951304	[]	[]	9	hSpCas9	negative selection	4055422
194138193	194138216	3	+	26780180	HT29	viability (GeCKOv2 library)	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	1.62008291435908	[]	[]	8	hSpCas9	negative selection	4055423
194136401	194136424	3	+	26780180	HT29	viability (GeCKOv2 library)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	1.07297470585257	[]	[]	5	hSpCas9	negative selection	4055424
194136960	194136983	3	+	26780180	HT29	viability (GeCKOv2 library)	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	2.1796935365037	[]	[]	9	hSpCas9	negative selection	4055425
194137782	194137805	3	+	26780180	HT29	viability (GeCKOv2 library)	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	2.00523310436753	[]	[]	9	hSpCas9	negative selection	4055426
194137001	194137024	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.1113927190360541	[4]	[2,1]	-3	hSpCas9	positive selection	4142296
194137026	194137049	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.021138097834979032	[3]	[1,2]	0	hSpCas9	positive selection	4142298
194137026	194137049	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-0.05108749304138993	[1]	[0,0]	-1	hSpCas9	positive selection	4142299
194136613	194136636	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.43241849169956437	[3]	[2,3]	8	hSpCas9	positive selection	4142300
194137001	194137024	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.5544027199567225	[3]	[3,2,5,0]	4	hSpCas9	positive selection	4206318
194137026	194137049	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	1.4941017359716597	[2]	[3,2,4,3]	9	hSpCas9	positive selection	4206320
194137026	194137049	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.6196966900708959	[1]	[0,2,1,0]	4	hSpCas9	positive selection	4206321
194136613	194136636	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.8779160520013023	[3]	[0,0,0,4]	6	hSpCas9	positive selection	4206322
194138193	194138216	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	1.070651731844765	[2]	[2,5]	9	hSpCas9	positive selection	4274856
194137782	194137805	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.008609415908825316	[2]	[2,1]	0	hSpCas9	positive selection	4274857
194137026	194137049	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.2982303209945461	[3]	[4,3]	6	hSpCas9	positive selection	4274858
194136401	194136424	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.083034081633555	[2]	[3,1]	1	hSpCas9	positive selection	4339117
194136960	194136983	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.07529542526227602	[2]	[2,1]	-1	hSpCas9	positive selection	4339118
194136434	194136457	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.7587687573048278	[3]	[3,5]	9	hSpCas9	positive selection	4339119
194136474	194136496	3	+	27760321	OCIAML3	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	0.6834775761905052	[116,81]	[133,109]	7	hSpCas9	negative selection	4406678
194136961	194136983	3	+	27760321	OCIAML3	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.17312194280335655	[602,496]	[298,484]	-2	hSpCas9	negative selection	4406679
194137034	194137056	3	+	27760321	OCIAML3	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	1.1745112611679343	[745,571]	[920,1458]	9	hSpCas9	negative selection	4406680
194137720	194137742	3	-	27760321	OCIAML3	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-0.017567452524717198	[620,547]	[356,572]	0	hSpCas9	negative selection	4406681
194137772	194137794	3	+	27760321	OCIAML3	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-1.4633131644293502	[250,214]	[74,53]	-8	hSpCas9	negative selection	4406682
194136474	194136496	3	+	27760321	OCIAML2	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	0.3740026472706748	[116,81]	[122,76]	5	hSpCas9	negative selection	4490141
194136961	194136983	3	+	27760321	OCIAML2	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.12934365869998177	[602,496]	[382,617]	1	hSpCas9	negative selection	4490142
194137034	194137056	3	+	27760321	OCIAML2	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	0.865118733554222	[745,571]	[838,1127]	9	hSpCas9	negative selection	4490143
194137720	194137742	3	-	27760321	OCIAML2	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-0.21784288353362286	[620,547]	[410,398]	-3	hSpCas9	negative selection	4490144
194137772	194137794	3	+	27760321	OCIAML2	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-0.2519907223374154	[250,214]	[124,200]	-3	hSpCas9	negative selection	4490145
194136474	194136496	3	+	27760321	MV411	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	0.18412268572983548	[116,81]	[32,134]	1	hSpCas9	negative selection	4573604
194136961	194136983	3	+	27760321	MV411	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	1.1805225005038107	[602,496]	[1110,379]	8	hSpCas9	negative selection	4573605
194137034	194137056	3	+	27760321	MV411	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	0.9397983394372199	[745,571]	[950,642]	7	hSpCas9	negative selection	4573606
194137720	194137742	3	-	27760321	MV411	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.5501135522811624	[620,547]	[466,708]	4	hSpCas9	negative selection	4573607
194137772	194137794	3	+	27760321	MV411	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	1.20295324186121	[250,214]	[451,203]	8	hSpCas9	negative selection	4573608
194136474	194136496	3	+	27760321	HL60	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	1.31392289767619	[116,81]	[110,293]	9	hSpCas9	negative selection	4657067
194136961	194136983	3	+	27760321	HL60	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.5368865236952163	[602,496]	[282,334]	-5	hSpCas9	negative selection	4657068
194137034	194137056	3	+	27760321	HL60	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	0.9555889622076884	[745,571]	[1006,1066]	8	hSpCas9	negative selection	4657069
194137720	194137742	3	-	27760321	HL60	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-0.3780076706824285	[620,547]	[390,340]	-4	hSpCas9	negative selection	4657070
194137772	194137794	3	+	27760321	HL60	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-0.09653986253710456	[250,214]	[192,160]	-1	hSpCas9	negative selection	4657071
194136474	194136496	3	+	27760321	HT1080	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	1.447168949284776	[81,63]	[74,83]	7	hSpCas9	negative selection	4740530
194136961	194136983	3	+	27760321	HT1080	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.08830823131199486	[496,387]	[182,146]	0	hSpCas9	negative selection	4740531
194137034	194137056	3	+	27760321	HT1080	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	1.0623285422714042	[571,446]	[368,483]	6	hSpCas9	negative selection	4740532
194137720	194137742	3	-	27760321	HT1080	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	0.5278240609142338	[547,427]	[275,284]	2	hSpCas9	negative selection	4740533
194137772	194137794	3	+	27760321	HT1080	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	0.4210036421449687	[214,167]	[41,167]	2	hSpCas9	negative selection	4740534
194136474	194136496	3	+	27760321	HT29	viability after 7 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-0.8651797795181557	[81,63]	[36,81,33]	-8	hSpCas9	negative selection	4823993
194136961	194136983	3	+	27760321	HT29	viability after 7 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.0949127990308731	[496,387]	[366,273,174]	-8	hSpCas9	negative selection	4823994
194137034	194137056	3	+	27760321	HT29	viability after 7 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-0.20790472811419858	[571,446]	[569,748,387]	-3	hSpCas9	negative selection	4823995
194137720	194137742	3	-	27760321	HT29	viability after 7 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-1.1715035446866189	[547,427]	[179,386,254]	-8	hSpCas9	negative selection	4823996
194137772	194137794	3	+	27760321	HT29	viability after 7 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-1.11880438378746	[214,167]	[72,76,181]	-8	hSpCas9	negative selection	4823997
194136474	194136496	3	+	27760321	HT29	viability after 25 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-3.8679383775500726	[81,63]	[4,7,3]	-9	hSpCas9	negative selection	4907456
194136961	194136983	3	+	27760321	HT29	viability after 25 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-3.3656316441675087	[496,387]	[59,40,44]	-9	hSpCas9	negative selection	4907457
194137034	194137056	3	+	27760321	HT29	viability after 25 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-1.4275277123522527	[571,446]	[117,159,395]	-7	hSpCas9	negative selection	4907458
194137720	194137742	3	-	27760321	HT29	viability after 25 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-6.713718303135853	[547,427]	[12,0,0]	-9	hSpCas9	negative selection	4907459
194137772	194137794	3	+	27760321	HT29	viability after 25 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-5.758260793907979	[214,167]	[0,9,0]	-9	hSpCas9	negative selection	4907460
194136474	194136496	3	+	27760321	HT29	viability after 22 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-6.3990111777607135	[81,63]	[0,0,0]	-9	hSpCas9	negative selection	4990919
194136961	194136983	3	+	27760321	HT29	viability after 22 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-4.1416890717375985	[496,387]	[4,10,71]	-9	hSpCas9	negative selection	4990920
194137034	194137056	3	+	27760321	HT29	viability after 22 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-1.5010041225607273	[571,446]	[147,161,316]	-7	hSpCas9	negative selection	4990921
194137720	194137742	3	-	27760321	HT29	viability after 22 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-9.13998504274798	[547,427]	[0,0,0]	-9	hSpCas9	negative selection	4990922
194137772	194137794	3	+	27760321	HT29	viability after 22 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-5.780664854255954	[214,167]	[5,4,0]	-9	hSpCas9	negative selection	4990923
194136474	194136496	3	+	27760321	HT29	viability after 19 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-5.110473792163435	[81,63]	[0,0,4]	-9	hSpCas9	negative selection	5074382
194136961	194136983	3	+	27760321	HT29	viability after 19 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-3.0254809247862524	[496,387]	[54,130,1]	-8	hSpCas9	negative selection	5074383
194137034	194137056	3	+	27760321	HT29	viability after 19 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-1.153752501677106	[571,446]	[409,126,263]	-7	hSpCas9	negative selection	5074384
194137720	194137742	3	-	27760321	HT29	viability after 19 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-9.124144990324767	[547,427]	[0,0,0]	-9	hSpCas9	negative selection	5074385
194137772	194137794	3	+	27760321	HT29	viability after 19 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-3.4108258166364513	[214,167]	[1,41,15]	-9	hSpCas9	negative selection	5074386
194136474	194136496	3	+	27760321	HT29	viability after 16 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-4.5563328865687085	[81,63]	[8,0,0]	-9	hSpCas9	negative selection	5157845
194136961	194136983	3	+	27760321	HT29	viability after 16 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-4.016549583527208	[496,387]	[23,35,30]	-9	hSpCas9	negative selection	5157846
194137034	194137056	3	+	27760321	HT29	viability after 16 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-0.7586307145604374	[571,446]	[256,345,399]	-6	hSpCas9	negative selection	5157847
194137720	194137742	3	-	27760321	HT29	viability after 16 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-5.412563911695205	[547,427]	[2,32,0]	-9	hSpCas9	negative selection	5157848
194137772	194137794	3	+	27760321	HT29	viability after 16 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-4.900100372535852	[214,167]	[0,4,14]	-9	hSpCas9	negative selection	5157849
194136474	194136496	3	+	27760321	HT29	viability after 13 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-0.7093816876210637	[81,63]	[44,51,57]	-6	hSpCas9	negative selection	5241308
194136961	194136983	3	+	27760321	HT29	viability after 13 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.938171646336716	[496,387]	[223,117,63]	-8	hSpCas9	negative selection	5241309
194137034	194137056	3	+	27760321	HT29	viability after 13 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-0.6232613760216552	[571,446]	[246,545,359]	-6	hSpCas9	negative selection	5241310
194137720	194137742	3	-	27760321	HT29	viability after 13 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-3.6306431327485726	[547,427]	[6,114,16]	-9	hSpCas9	negative selection	5241311
194137772	194137794	3	+	27760321	HT29	viability after 13 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-3.2195202433033496	[214,167]	[16,3,48]	-9	hSpCas9	negative selection	5241312
194136474	194136496	3	+	27760321	HT29	viability after 10 days	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-1.3704267838808026	[81,63]	[57,9,36]	-8	hSpCas9	negative selection	5324771
194136961	194136983	3	+	27760321	HT29	viability after 10 days	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.4956522270537072	[496,387]	[235,142,206]	-8	hSpCas9	negative selection	5324772
194137034	194137056	3	+	27760321	HT29	viability after 10 days	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	-0.21427947262652702	[571,446]	[810,489,346]	-3	hSpCas9	negative selection	5324773
194137720	194137742	3	-	27760321	HT29	viability after 10 days	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-2.681864165026152	[547,427]	[145,54,82]	-9	hSpCas9	negative selection	5324774
194137772	194137794	3	+	27760321	HT29	viability after 10 days	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-1.2400850013810643	[214,167]	[22,222,61]	-8	hSpCas9	negative selection	5324775
194136474	194136496	3	+	27760321	MOLM13	viability	TCTGAGCACAGAAAGGTAAGGG	HES1	ENSG00000114315	-1.6236567471378667	[116,81]	[37,0]	-7	hSpCas9	negative selection	5408234
194136961	194136983	3	+	27760321	MOLM13	viability	AGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.6765599857830459	[602,496]	[571,426]	5	hSpCas9	negative selection	5408235
194137034	194137056	3	+	27760321	MOLM13	viability	GGGCGCAGATGACGGGTGAGGG	HES1	ENSG00000114315	2.117641848851468	[745,571]	[916,2183]	9	hSpCas9	negative selection	5408236
194137720	194137742	3	-	27760321	MOLM13	viability	GCACTCGCTGAAGCCGGCTCGG	HES1	ENSG00000114315	-0.035097728030341335	[620,547]	[411,243]	0	hSpCas9	negative selection	5408237
194137772	194137794	3	+	27760321	MOLM13	viability	TGCGAGGGCGTTAATACCGAGG	HES1	ENSG00000114315	-1.1804040508217206	[250,214]	[39,72]	-6	hSpCas9	negative selection	5408238
194136144	194136167	3	+	27661255	K562	viability	GATCACACAGGATCCGGAGCTGG	HES1	ENSG00000114315	0.23810480059956962	[111,168]	[152,112]	7	dCas9-KRAB	negative selection	5484475
194136202	194136225	3	-	27661255	K562	viability	GTAGCGCTGTTCCAGGACCAAGG	HES1	ENSG00000114315	0.1186401405119234	[704,879]	[757,621]	4	dCas9-KRAB	negative selection	5484476
194138193	194138216	3	+	27260156	BXPC3	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.8025649740505985	[228]	[150,117,131,147]	-9	hSpCas9	negative selection	5547316
194137782	194137805	3	+	27260156	BXPC3	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-1.1035799662052208	[420]	[174,191,207,252]	-9	hSpCas9	negative selection	5547317
194137026	194137049	3	-	27260156	BXPC3	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	-0.13296031536572128	[886]	[810,683,1063,833]	-3	hSpCas9	negative selection	5547318
194136401	194136424	3	+	27260156	BXPC3	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.46889547403324805	[303]	[280,171,205,258]	-7	hSpCas9	negative selection	5611577
194136960	194136983	3	+	27260156	BXPC3	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.6347814455160005	[391]	[227,271,227,337]	-8	hSpCas9	negative selection	5611578
194136434	194136457	3	+	27260156	BXPC3	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.8110707054378525	[668]	[353,292,477,490]	-9	hSpCas9	negative selection	5611579
194138193	194138216	3	+	27260156	A673	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.23485631287999953	[228]	[375,250,253,426]	5	hSpCas9	negative selection	5668567
194137782	194137805	3	+	27260156	A673	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.3827950104162467	[420]	[475,330,452,295]	-7	hSpCas9	negative selection	5668568
194137026	194137049	3	-	27260156	A673	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.16044099354963304	[886]	[1296,1229,1074,1167]	4	hSpCas9	negative selection	5668569
194136401	194136424	3	+	27260156	A673	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.19410510943299575	[303]	[494,308,428,449]	4	hSpCas9	negative selection	5732828
194136960	194136983	3	+	27260156	A673	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.020925643959577467	[391]	[537,422,432,470]	0	hSpCas9	negative selection	5732829
194136434	194136457	3	+	27260156	A673	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.14338961942018535	[668]	[858,570,748,748]	-4	hSpCas9	negative selection	5732830
194138193	194138216	3	+	27260156	A375	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.3886812233644741	[228]	[323,404,292,380]	5	hSpCas9	negative selection	5789818
194137782	194137805	3	+	27260156	A375	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.3771710955781668	[420]	[667,364,284,214]	-5	hSpCas9	negative selection	5789819
194137026	194137049	3	-	27260156	A375	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.3357899067975231	[886]	[1442,1479,1084,1248]	5	hSpCas9	negative selection	5789820
194136401	194136424	3	+	27260156	A375	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.05360333443395804	[303]	[302,621,223,265]	-1	hSpCas9	negative selection	5854079
194136960	194136983	3	+	27260156	A375	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.2261869602286355	[391]	[479,450,360,292]	-3	hSpCas9	negative selection	5854080
194136434	194136457	3	+	27260156	A375	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.3121716529032774	[668]	[505,790,743,509]	-4	hSpCas9	negative selection	5854081
194138193	194138216	3	+	27260156	COLO741	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.09255395362604535	[228]	[287,236,296]	-2	hSpCas9	negative selection	5911069
194137782	194137805	3	+	27260156	COLO741	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.2067939926588393	[420]	[548,429,427]	-4	hSpCas9	negative selection	5911070
194137026	194137049	3	-	27260156	COLO741	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.1959676390597903	[886]	[1325,1352,1220]	4	hSpCas9	negative selection	5911071
194136401	194136424	3	+	27260156	COLO741	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.06147462553433569	[303]	[387,382,347]	-1	hSpCas9	negative selection	5975330
194136960	194136983	3	+	27260156	COLO741	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.05803236633655856	[391]	[518,537,506]	1	hSpCas9	negative selection	5975331
194136434	194136457	3	+	27260156	COLO741	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.07224759928792274	[668]	[1069,804,599]	-1	hSpCas9	negative selection	5975332
194138193	194138216	3	+	27260156	CAL120	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.3663627257895219	[228]	[477,298,341]	5	hSpCas9	negative selection	6032320
194137782	194137805	3	+	27260156	CAL120	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.14737156202828927	[420]	[829,361,283]	-2	hSpCas9	negative selection	6032321
194137026	194137049	3	-	27260156	CAL120	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.24213433035264964	[886]	[1407,1479,1047]	3	hSpCas9	negative selection	6032322
194136401	194136424	3	+	27260156	CAL120	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.2547777672100735	[303]	[373,290,294]	-4	hSpCas9	negative selection	6096581
194136960	194136983	3	+	27260156	CAL120	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.2159953780765193	[391]	[652,631,429]	3	hSpCas9	negative selection	6096582
194136434	194136457	3	+	27260156	CAL120	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.3476410978178093	[668]	[517,717,704]	-5	hSpCas9	negative selection	6096583
194138193	194138216	3	+	27260156	CADOES1	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.23179476972089197	[228]	[231,133,158,200]	-4	hSpCas9	negative selection	6153571
194137782	194137805	3	+	27260156	CADOES1	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.1252716970571286	[420]	[310,411,409,300]	-2	hSpCas9	negative selection	6153572
194137026	194137049	3	-	27260156	CADOES1	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.2427465946355546	[886]	[1067,868,966,1000]	4	hSpCas9	negative selection	6153573
194136401	194136424	3	+	27260156	CADOES1	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.04151649207329833	[303]	[216,286,346,313]	0	hSpCas9	negative selection	6217832
194136960	194136983	3	+	27260156	CADOES1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.4375539679700823	[391]	[471,736,390,370]	7	hSpCas9	negative selection	6217833
194136434	194136457	3	+	27260156	CADOES1	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.16521742859262134	[668]	[530,747,618,900]	3	hSpCas9	negative selection	6217834
194138193	194138216	3	+	27260156	EWS502	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.19760827644585155	[228]	[306,249,227,326]	3	hSpCas9	negative selection	6274822
194137782	194137805	3	+	27260156	EWS502	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.555923745222114	[420]	[323,247,325,314]	-7	hSpCas9	negative selection	6274823
194137026	194137049	3	-	27260156	EWS502	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.23435846784088465	[886]	[1086,1164,923,1247]	4	hSpCas9	negative selection	6274824
194136401	194136424	3	+	27260156	EWS502	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.0043740304702486466	[303]	[304,357,297,321]	0	hSpCas9	negative selection	6339083
194136960	194136983	3	+	27260156	EWS502	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.06698654509894172	[391]	[380,351,549,468]	1	hSpCas9	negative selection	6339084
194136434	194136457	3	+	27260156	EWS502	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.23558990667751284	[668]	[568,621,620,595]	-4	hSpCas9	negative selection	6339085
194138193	194138216	3	+	27260156	EW8	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.4366494255141433	[228]	[310,193,282,216]	7	hSpCas9	negative selection	6396073
194137782	194137805	3	+	27260156	EW8	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.48307871277149944	[420]	[262,264,297,142]	-7	hSpCas9	negative selection	6396074
194137026	194137049	3	-	27260156	EW8	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.23950926840843223	[886]	[1048,736,709,940]	4	hSpCas9	negative selection	6396075
194136401	194136424	3	+	27260156	EW8	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.11362826077290422	[303]	[248,259,172,396]	2	hSpCas9	negative selection	6460334
194136960	194136983	3	+	27260156	EW8	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.07111666652241394	[391]	[365,303,275,400]	1	hSpCas9	negative selection	6460335
194136434	194136457	3	+	27260156	EW8	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.12245765004110148	[668]	[564,480,540,403]	-2	hSpCas9	negative selection	6460336
194138193	194138216	3	+	27260156	CORL105	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.11587481118070975	[228]	[273,308,327,255]	2	hSpCas9	negative selection	6517324
194137782	194137805	3	+	27260156	CORL105	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.46261346485465976	[420]	[419,329,361,321]	-7	hSpCas9	negative selection	6517325
194137026	194137049	3	-	27260156	CORL105	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.5460748211789418	[886]	[1589,1382,1740,1390]	8	hSpCas9	negative selection	6517326
194136401	194136424	3	+	27260156	CORL105	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.49808321721510906	[303]	[558,332,807,363]	8	hSpCas9	negative selection	6581585
194136960	194136983	3	+	27260156	CORL105	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.043478423799287846	[391]	[384,400,551,563]	0	hSpCas9	negative selection	6581586
194136434	194136457	3	+	27260156	CORL105	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.07504082121913658	[668]	[876,712,1015,727]	1	hSpCas9	negative selection	6581587
194138193	194138216	3	+	27260156	HS294T	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.17768536469279728	[228]	[75,92,112,124]	2	hSpCas9	negative selection	6638575
194137782	194137805	3	+	27260156	HS294T	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.1473827204437284	[420]	[82,208,184,107]	-2	hSpCas9	negative selection	6638576
194137026	194137049	3	-	27260156	HS294T	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.7866223005050282	[886]	[667,593,612,459]	8	hSpCas9	negative selection	6638577
194136401	194136424	3	+	27260156	HS294T	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.15755426170391862	[303]	[86,116,100,119]	-2	hSpCas9	negative selection	6702836
194136960	194136983	3	+	27260156	HS294T	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.40081225600211146	[391]	[142,353,137,157]	5	hSpCas9	negative selection	6702837
194136434	194136457	3	+	27260156	HS294T	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.216275654770003	[668]	[222,386,287,308]	3	hSpCas9	negative selection	6702838
194138193	194138216	3	+	27260156	HCC44	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.06454687013815152	[228]	[162,247,327,342]	1	hSpCas9	negative selection	6759826
194137782	194137805	3	+	27260156	HCC44	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	0.0770362099208554	[420]	[520,579,541,363]	1	hSpCas9	negative selection	6759827
194137026	194137049	3	-	27260156	HCC44	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.2695406791853404	[886]	[1161,1115,1346,1233]	4	hSpCas9	negative selection	6759828
194136401	194136424	3	+	27260156	HCC44	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.07689315476945013	[303]	[308,301,474,383]	1	hSpCas9	negative selection	6824087
194136960	194136983	3	+	27260156	HCC44	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.32058872779910225	[391]	[513,733,646,309]	5	hSpCas9	negative selection	6824088
194136434	194136457	3	+	27260156	HCC44	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.37744787135111507	[668]	[552,442,660,694]	-5	hSpCas9	negative selection	6824089
194138193	194138216	3	+	27260156	G402	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.061727809703388425	[228]	[320,368,188,294]	0	hSpCas9	negative selection	6881077
194137782	194137805	3	+	27260156	G402	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.39164378094088853	[420]	[521,399,352,312]	-5	hSpCas9	negative selection	6881078
194137026	194137049	3	-	27260156	G402	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.4546027959574107	[886]	[1216,1842,1078,1756]	5	hSpCas9	negative selection	6881079
194136401	194136424	3	+	27260156	G402	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.417541965267088	[303]	[437,502,598,434]	5	hSpCas9	negative selection	6945338
194136960	194136983	3	+	27260156	G402	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.10025904212681414	[391]	[329,420,252,745]	-1	hSpCas9	negative selection	6945339
194136434	194136457	3	+	27260156	G402	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.05591181439976939	[668]	[945,793,767,659]	0	hSpCas9	negative selection	6945340
194138193	194138216	3	+	27260156	L33	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.34072446015510605	[228]	[185,85,131,117]	-7	hSpCas9	negative selection	7002328
194137782	194137805	3	+	27260156	L33	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.49405106913743163	[420]	[338,91,190,326]	-8	hSpCas9	negative selection	7002329
194137026	194137049	3	-	27260156	L33	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.13176043031113316	[886]	[897,419,627,966]	3	hSpCas9	negative selection	7002330
194136401	194136424	3	+	27260156	L33	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.4241516969178383	[303]	[214,98,141,223]	-7	hSpCas9	negative selection	7066589
194136960	194136983	3	+	27260156	L33	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.1825609161564305	[391]	[384,122,225,335]	-4	hSpCas9	negative selection	7066590
194136434	194136457	3	+	27260156	L33	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.4479811627469585	[668]	[431,198,289,582]	-8	hSpCas9	negative selection	7066591
194138193	194138216	3	+	27260156	K562	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.7703464511485016	[228]	[418,274,372,322]	8	hSpCas9	negative selection	7123579
194137782	194137805	3	+	27260156	K562	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.8304911247270321	[420]	[258,256,176,158]	-7	hSpCas9	negative selection	7123580
194137026	194137049	3	-	27260156	K562	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.6389112774779216	[886]	[1330,1436,1014,1143]	7	hSpCas9	negative selection	7123581
194136401	194136424	3	+	27260156	K562	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.26587857776294455	[303]	[458,93,141,214]	-3	hSpCas9	negative selection	7187840
194136960	194136983	3	+	27260156	K562	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.3776838553705876	[391]	[296,557,681,281]	5	hSpCas9	negative selection	7187841
194136434	194136457	3	+	27260156	K562	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.1882302741520031	[668]	[549,577,641,338]	-2	hSpCas9	negative selection	7187842
194138193	194138216	3	+	27260156	HT29	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.08275042849560688	[228]	[232,379,196,248]	-2	hSpCas9	negative selection	7244830
194137782	194137805	3	+	27260156	HT29	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.5870995145164601	[420]	[439,333,294,302]	-7	hSpCas9	negative selection	7244831
194137026	194137049	3	-	27260156	HT29	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.21186184904032646	[886]	[1320,1209,1115,1330]	4	hSpCas9	negative selection	7244832
194136401	194136424	3	+	27260156	HT29	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.12843508716436214	[303]	[468,540,263,360]	2	hSpCas9	negative selection	7309091
194136960	194136983	3	+	27260156	HT29	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.20261256662062638	[391]	[409,558,430,281]	-4	hSpCas9	negative selection	7309092
194136434	194136457	3	+	27260156	HT29	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.3225416843835285	[668]	[760,686,606,563]	-6	hSpCas9	negative selection	7309093
194138193	194138216	3	+	27260156	MHHES1	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.27096818786705	[228]	[279,399,309,263]	5	hSpCas9	negative selection	7366081
194137782	194137805	3	+	27260156	MHHES1	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.18457852433795718	[420]	[286,523,616,263]	-3	hSpCas9	negative selection	7366082
194137026	194137049	3	-	27260156	MHHES1	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.46745545453873116	[886]	[1377,1803,1355,1070]	8	hSpCas9	negative selection	7366083
194136401	194136424	3	+	27260156	MHHES1	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.13761076908151487	[303]	[336,553,418,234]	2	hSpCas9	negative selection	7430342
194136960	194136983	3	+	27260156	MHHES1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.024264090930356197	[391]	[507,445,424,419]	0	hSpCas9	negative selection	7430343
194136434	194136457	3	+	27260156	MHHES1	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.38743633478306727	[668]	[693,672,484,483]	-6	hSpCas9	negative selection	7430344
194138193	194138216	3	+	27260156	MEWO	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.5808229108523469	[228]	[353,271,341]	9	hSpCas9	negative selection	7487332
194137782	194137805	3	+	27260156	MEWO	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.3112012121296817	[420]	[387,305,271]	-6	hSpCas9	negative selection	7487333
194137026	194137049	3	-	27260156	MEWO	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.32780630271079236	[886]	[1217,953,986]	7	hSpCas9	negative selection	7487334
194136401	194136424	3	+	27260156	MEWO	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.612185944995367	[303]	[536,422,363]	9	hSpCas9	negative selection	7551593
194136960	194136983	3	+	27260156	MEWO	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.007651529593687478	[391]	[439,341,326]	0	hSpCas9	negative selection	7551594
194136434	194136457	3	+	27260156	MEWO	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.06362455583933124	[668]	[643,700,614]	1	hSpCas9	negative selection	7551595
194138193	194138216	3	+	27260156	LNCAPCLONEFGC	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.055446474333849416	[228]	[164,192,236,209]	-1	hSpCas9	negative selection	7608583
194137782	194137805	3	+	27260156	LNCAPCLONEFGC	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.20216283106156507	[420]	[310,359,369,288]	-3	hSpCas9	negative selection	7608584
194137026	194137049	3	-	27260156	LNCAPCLONEFGC	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.22004110985581715	[886]	[724,861,1212,992]	3	hSpCas9	negative selection	7608585
194136401	194136424	3	+	27260156	LNCAPCLONEFGC	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.014352147753842859	[303]	[358,220,233,293]	0	hSpCas9	negative selection	7672844
194136960	194136983	3	+	27260156	LNCAPCLONEFGC	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.06917978877983239	[391]	[271,293,345,446]	-1	hSpCas9	negative selection	7672845
194136434	194136457	3	+	27260156	LNCAPCLONEFGC	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.18608105294661115	[668]	[524,431,517,659]	-3	hSpCas9	negative selection	7672846
194138193	194138216	3	+	27260156	PANC0327	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.5917779033941064	[228]	[71,110,245,108]	-7	hSpCas9	negative selection	7729834
194137782	194137805	3	+	27260156	PANC0327	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.7958461514082036	[420]	[311,209,104,242]	-8	hSpCas9	negative selection	7729835
194137026	194137049	3	-	27260156	PANC0327	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.20690957511104424	[886]	[629,1362,831,730]	3	hSpCas9	negative selection	7729836
194136401	194136424	3	+	27260156	PANC0327	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.7329804982439536	[303]	[204,179,112,152]	-7	hSpCas9	negative selection	7794095
194136960	194136983	3	+	27260156	PANC0327	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.5437191812188914	[391]	[265,242,176,270]	-6	hSpCas9	negative selection	7794096
194136434	194136457	3	+	27260156	PANC0327	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.2886696436090309	[668]	[469,459,515,501]	-4	hSpCas9	negative selection	7794097
194138193	194138216	3	+	27260156	NCIH2009	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.4587264745535944	[228]	[375,483,444]	6	hSpCas9	negative selection	7851085
194137782	194137805	3	+	27260156	NCIH2009	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.42326994365611686	[420]	[442,440,431]	-5	hSpCas9	negative selection	7851086
194137026	194137049	3	-	27260156	NCIH2009	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.6840748890901033	[886]	[2675,1788,1643]	8	hSpCas9	negative selection	7851087
194136401	194136424	3	+	27260156	NCIH2009	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.06384348472846169	[303]	[561,357,435]	0	hSpCas9	negative selection	7915346
194136960	194136983	3	+	27260156	NCIH2009	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.1574273650004721	[391]	[588,530,370]	-2	hSpCas9	negative selection	7915347
194136434	194136457	3	+	27260156	NCIH2009	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.43852314237363316	[668]	[694,688,684]	-5	hSpCas9	negative selection	7915348
194138193	194138216	3	+	27260156	NCIH1373	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.6373142650052687	[228]	[610,295,466,66]	6	hSpCas9	negative selection	7972336
194137782	194137805	3	+	27260156	NCIH1373	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.7310650118659001	[420]	[404,339,278,29]	-6	hSpCas9	negative selection	7972337
194137026	194137049	3	-	27260156	NCIH1373	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.6639911841467211	[886]	[1593,1099,1706,516]	6	hSpCas9	negative selection	7972338
194136401	194136424	3	+	27260156	NCIH1373	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.24130721039969316	[303]	[312,266,340,60]	-2	hSpCas9	negative selection	8036597
194136960	194136983	3	+	27260156	NCIH1373	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.15975338576472803	[391]	[768,329,362,148]	1	hSpCas9	negative selection	8036598
194136434	194136457	3	+	27260156	NCIH1373	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.061932613719310636	[668]	[1077,403,554,246]	0	hSpCas9	negative selection	8036599
194138193	194138216	3	+	27260156	PATU8902	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.44767649168641177	[228]	[648,356,334,415]	4	hSpCas9	negative selection	8093587
194137782	194137805	3	+	27260156	PATU8902	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-1.6681599652190917	[420]	[172,204,103,287]	-8	hSpCas9	negative selection	8093588
194137026	194137049	3	-	27260156	PATU8902	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.0386572246857807	[886]	[1103,1279,923,1927]	0	hSpCas9	negative selection	8093589
194136401	194136424	3	+	27260156	PATU8902	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.1997480133871622	[303]	[344,367,563,666]	2	hSpCas9	negative selection	8157848
194136960	194136983	3	+	27260156	PATU8902	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.1306252372218964	[391]	[423,688,572,723]	1	hSpCas9	negative selection	8157849
194136434	194136457	3	+	27260156	PATU8902	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.06844147471703088	[668]	[855,1354,415,1065]	0	hSpCas9	negative selection	8157850
194138193	194138216	3	+	27260156	PANC1	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.02988837379649123	[228]	[85,221,252,211]	0	hSpCas9	negative selection	8214838
194137782	194137805	3	+	27260156	PANC1	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.4743206036716176	[420]	[287,255,243,248]	-6	hSpCas9	negative selection	8214839
194137026	194137049	3	-	27260156	PANC1	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.16531165409673643	[886]	[881,1140,898,584]	2	hSpCas9	negative selection	8214840
194136401	194136424	3	+	27260156	PANC1	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.06874853420424176	[303]	[242,329,265,180]	-1	hSpCas9	negative selection	8279099
194136960	194136983	3	+	27260156	PANC1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.3069601855065075	[391]	[265,389,247,213]	-5	hSpCas9	negative selection	8279100
194136434	194136457	3	+	27260156	PANC1	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.19167634120121457	[668]	[532,888,810,464]	3	hSpCas9	negative selection	8279101
194138193	194138216	3	+	27260156	PANC0813	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.061540073992586986	[228]	[178,296,384,253]	1	hSpCas9	negative selection	8336089
194137782	194137805	3	+	27260156	PANC0813	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.6096394033053438	[420]	[456,291,376,189]	-7	hSpCas9	negative selection	8336090
194137026	194137049	3	-	27260156	PANC0813	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.4967164760292545	[886]	[1349,1798,1337,1383]	7	hSpCas9	negative selection	8336091
194136401	194136424	3	+	27260156	PANC0813	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.27684158968233163	[303]	[371,247,295,270]	-4	hSpCas9	negative selection	8400350
194136960	194136983	3	+	27260156	PANC0813	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.21485327357322237	[391]	[453,409,376,352]	-3	hSpCas9	negative selection	8400351
194136434	194136457	3	+	27260156	PANC0813	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.3435378394794673	[668]	[747,533,482,716]	-5	hSpCas9	negative selection	8400352
194138193	194138216	3	+	27260156	RDES	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.21277434163580577	[228]	[252,239,320,435]	3	hSpCas9	negative selection	8457340
194137782	194137805	3	+	27260156	RDES	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.32860067646208996	[420]	[266,309,436,582]	-5	hSpCas9	negative selection	8457341
194137026	194137049	3	-	27260156	RDES	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.3461475534644075	[886]	[1125,1273,1478,1314]	5	hSpCas9	negative selection	8457342
194136401	194136424	3	+	27260156	RDES	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.08245748595653335	[303]	[294,475,289,417]	1	hSpCas9	negative selection	8521601
194136960	194136983	3	+	27260156	RDES	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.0139163646355141	[391]	[355,389,471,604]	0	hSpCas9	negative selection	8521602
194136434	194136457	3	+	27260156	RDES	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.039970259984472845	[668]	[590,915,728,750]	0	hSpCas9	negative selection	8521603
194138193	194138216	3	+	27260156	PC3	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.14790809981940123	[228]	[160,278,336,281]	3	hSpCas9	negative selection	8578591
194137782	194137805	3	+	27260156	PC3	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.300406800882989	[420]	[163,392,760,252]	-6	hSpCas9	negative selection	8578592
194137026	194137049	3	-	27260156	PC3	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.1019338020660171	[886]	[658,818,1537,1046]	2	hSpCas9	negative selection	8578593
194136401	194136424	3	+	27260156	PC3	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.03880901338670162	[303]	[204,269,548,262]	-1	hSpCas9	negative selection	8642852
194136960	194136983	3	+	27260156	PC3	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.26578037447582553	[391]	[245,574,795,439]	6	hSpCas9	negative selection	8642853
194136434	194136457	3	+	27260156	PC3	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.1395302767425915	[668]	[371,476,975,801]	-3	hSpCas9	negative selection	8642854
194138193	194138216	3	+	27260156	PATU8988T	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.9290925596236775	[228]	[173,542,436,552]	9	hSpCas9	negative selection	8699842
194137782	194137805	3	+	27260156	PATU8988T	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.3682812232947808	[420]	[313,248,370,319]	-6	hSpCas9	negative selection	8699843
194137026	194137049	3	-	27260156	PATU8988T	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.2982378768897235	[886]	[1086,1222,927,989]	5	hSpCas9	negative selection	8699844
194136401	194136424	3	+	27260156	PATU8988T	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.10874674210818303	[303]	[263,362,249,216]	-2	hSpCas9	negative selection	8764103
194136960	194136983	3	+	27260156	PATU8988T	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.10419525644171843	[391]	[261,519,434,422]	1	hSpCas9	negative selection	8764104
194136434	194136457	3	+	27260156	PATU8988T	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.1993309584393067	[668]	[684,607,367,600]	-3	hSpCas9	negative selection	8764105
194138193	194138216	3	+	27260156	T47D	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.5968320440826442	[228]	[235,158,134,177]	-8	hSpCas9	negative selection	8821093
194137782	194137805	3	+	27260156	T47D	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.9114828617713098	[420]	[340,244,230,226]	-9	hSpCas9	negative selection	8821094
194137026	194137049	3	-	27260156	T47D	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.020876498963129264	[886]	[1069,1024,1017,1083]	0	hSpCas9	negative selection	8821095
194136401	194136424	3	+	27260156	T47D	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.43165130789614947	[303]	[250,235,278,286]	-7	hSpCas9	negative selection	8885354
194136960	194136983	3	+	27260156	T47D	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.3577120556237703	[391]	[420,382,321,295]	-6	hSpCas9	negative selection	8885355
194136434	194136457	3	+	27260156	T47D	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.5200488941768115	[668]	[507,503,556,609]	-8	hSpCas9	negative selection	8885356
194138193	194138216	3	+	27260156	SU8686	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.10117225053017842	[228]	[239,223,267,243]	1	hSpCas9	negative selection	8942344
194137782	194137805	3	+	27260156	SU8686	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.15111603864542067	[420]	[354,337,408,412]	-3	hSpCas9	negative selection	8942345
194137026	194137049	3	-	27260156	SU8686	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.5496763273398028	[886]	[1171,1269,1084,1686]	8	hSpCas9	negative selection	8942346
194136401	194136424	3	+	27260156	SU8686	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.18299426994888746	[303]	[234,335,367,459]	3	hSpCas9	negative selection	9006605
194136960	194136983	3	+	27260156	SU8686	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.04216731137449281	[391]	[303,413,382,415]	0	hSpCas9	negative selection	9006606
194136434	194136457	3	+	27260156	SU8686	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.013788071119165357	[668]	[642,642,567,852]	0	hSpCas9	negative selection	9006607
194138193	194138216	3	+	27260156	SKES1	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.10959236444608633	[228]	[202,324,221,237]	2	hSpCas9	negative selection	9063595
194137782	194137805	3	+	27260156	SKES1	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.3559538521555065	[420]	[412,379,241,296]	-7	hSpCas9	negative selection	9063596
194137026	194137049	3	-	27260156	SKES1	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.16827335576791336	[886]	[938,1131,1009,904]	3	hSpCas9	negative selection	9063597
194136401	194136424	3	+	27260156	SKES1	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.12820645990817858	[303]	[192,301,267,328]	-3	hSpCas9	negative selection	9127856
194136960	194136983	3	+	27260156	SKES1	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.24264377152762306	[391]	[358,393,328,256]	-5	hSpCas9	negative selection	9127857
194136434	194136457	3	+	27260156	SKES1	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.15104516198798462	[668]	[855,674,367,551]	-3	hSpCas9	negative selection	9127858
194138193	194138216	3	+	27260156	TOV112D	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.006530265349592668	[228]	[329,244,137,212]	0	hSpCas9	negative selection	9184846
194137782	194137805	3	+	27260156	TOV112D	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.5399648430101844	[420]	[313,399,233,241]	-8	hSpCas9	negative selection	9184847
194137026	194137049	3	-	27260156	TOV112D	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.407600007157373	[886]	[1144,1513,1009,1123]	7	hSpCas9	negative selection	9184848
194136401	194136424	3	+	27260156	TOV112D	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.24102608381485757	[303]	[312,780,285,163]	4	hSpCas9	negative selection	9249107
194136960	194136983	3	+	27260156	TOV112D	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.3909160495286611	[391]	[245,354,328,276]	-6	hSpCas9	negative selection	9249108
194136434	194136457	3	+	27260156	TOV112D	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.11061881348445668	[668]	[632,805,552,907]	2	hSpCas9	negative selection	9249109
194138193	194138216	3	+	27260156	TC71	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	0.5247385149313786	[228]	[278,471,426,225]	9	hSpCas9	negative selection	9306097
194137782	194137805	3	+	27260156	TC71	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.4300349298129644	[420]	[356,390,296,292]	-8	hSpCas9	negative selection	9306098
194137026	194137049	3	-	27260156	TC71	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.1912277455914978	[886]	[1238,933,1039,1129]	5	hSpCas9	negative selection	9306099
194136401	194136424	3	+	27260156	TC71	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	0.3189365944507252	[303]	[415,362,385,464]	7	hSpCas9	negative selection	9370358
194136960	194136983	3	+	27260156	TC71	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.017854064752349796	[391]	[399,476,368,415]	0	hSpCas9	negative selection	9370359
194136434	194136457	3	+	27260156	TC71	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.3195010311861279	[668]	[549,445,626,680]	-7	hSpCas9	negative selection	9370360
194138193	194138216	3	+	27260156	TC32	viability	CGCTTACGGCGGACTCCATGTGG	HES1	ENSG00000114315	-0.24938759493579865	[228]	[125,125,287,222]	-4	hSpCas9	negative selection	9427348
194137782	194137805	3	+	27260156	TC32	viability	TTAATACCGAGGTGCGCACTCGG	HES1	ENSG00000114315	-0.7720941057727162	[420]	[222,201,203,293]	-9	hSpCas9	negative selection	9427349
194137026	194137049	3	-	27260156	TC32	viability	CCGTCATCTGCGCCCGCTGCAGG	HES1	ENSG00000114315	0.22682266564461917	[886]	[658,870,1426,1048]	4	hSpCas9	negative selection	9427350
194136401	194136424	3	+	27260156	TC32	viability	GAAAAATTCCTCGTCCCCGGTGG	HES1	ENSG00000114315	-0.17387321286395263	[303]	[235,241,244,279]	-3	hSpCas9	negative selection	9491609
194136960	194136983	3	+	27260156	TC32	viability	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.15521026652253433	[391]	[347,238,475,295]	-3	hSpCas9	negative selection	9491610
194136434	194136457	3	+	27260156	TC32	viability	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.4760824984973027	[668]	[462,261,586,570]	-7	hSpCas9	negative selection	9491611
194136434	194136457	3	+	27869803	HPAFII	viability after 27 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.03047211011386719	[529]	[322,230,NaN]	0	hSpCas9	negative selection	9584064
194136436	194136459	3	-	27869803	HPAFII	viability after 27 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-2.417030762259736	[168]	[20,12,NaN]	-8	hSpCas9	negative selection	9584065
194136960	194136983	3	+	27869803	HPAFII	viability after 27 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-2.0513905899847016	[290]	[55,20,NaN]	-8	hSpCas9	negative selection	9584066
194137729	194137752	3	+	27869803	HPAFII	viability after 27 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.3989762589283221	[297]	[168,76,NaN]	-3	hSpCas9	negative selection	9584067
194137756	194137779	3	-	27869803	HPAFII	viability after 27 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.8710266490251288	[425]	[50,181,NaN]	-6	hSpCas9	negative selection	9584068
194138189	194138212	3	-	27869803	HPAFII	viability after 27 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.7193784821693421	[200]	[97,35,NaN]	-5	hSpCas9	negative selection	9584069
194136434	194136457	3	+	27869803	HPAFII	viability after 15 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.08041455177119228	[529]	[637,476,NaN]	-1	hSpCas9	negative selection	9666513
194136436	194136459	3	-	27869803	HPAFII	viability after 15 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.8487384256006013	[168]	[135,78,NaN]	-7	hSpCas9	negative selection	9666514
194136960	194136983	3	+	27869803	HPAFII	viability after 15 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.5386190718742183	[290]	[255,189,NaN]	-5	hSpCas9	negative selection	9666515
194137729	194137752	3	+	27869803	HPAFII	viability after 15 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.09181503876451247	[297]	[492,246,NaN]	1	hSpCas9	negative selection	9666516
194137756	194137779	3	-	27869803	HPAFII	viability after 15 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-0.8337934750221908	[425]	[283,239,NaN]	-7	hSpCas9	negative selection	9666517
194138189	194138212	3	-	27869803	HPAFII	viability after 15 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.09910024523097899	[200]	[168,221,NaN]	-1	hSpCas9	negative selection	9666518
194136434	194136457	3	+	27869803	ASPC1	viability after 36 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.13471630577835647	[1435]	[795,435,229]	-1	hSpCas9	negative selection	9748962
194136436	194136459	3	-	27869803	ASPC1	viability after 36 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-0.8498364046602005	[554]	[120,158,55]	-7	hSpCas9	negative selection	9748963
194136960	194136983	3	+	27869803	ASPC1	viability after 36 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.33751684350699374	[726]	[344,359,268]	3	hSpCas9	negative selection	9748964
194137729	194137752	3	+	27869803	ASPC1	viability after 36 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.34422322625060486	[710]	[398,455,140]	3	hSpCas9	negative selection	9748965
194137756	194137779	3	-	27869803	ASPC1	viability after 36 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.23123518475228622	[836]	[478,391,204]	2	hSpCas9	negative selection	9748966
194138189	194138212	3	-	27869803	ASPC1	viability after 36 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.5485364165247268	[343]	[258,44,218]	5	hSpCas9	negative selection	9748967
194136434	194136457	3	+	27869803	PATU8988S	viability after 35 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	1.2783995131341672	[1109]	[1046,1121,NaN]	9	hSpCas9	negative selection	9831411
194136436	194136459	3	-	27869803	PATU8988S	viability after 35 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.5775872384134492	[466]	[362,197,NaN]	6	hSpCas9	negative selection	9831412
194136960	194136983	3	+	27869803	PATU8988S	viability after 35 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-0.09007796461027756	[757]	[420,151,NaN]	-1	hSpCas9	negative selection	9831413
194137729	194137752	3	+	27869803	PATU8988S	viability after 35 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.5956415760138728	[936]	[469,670,NaN]	6	hSpCas9	negative selection	9831414
194137756	194137779	3	-	27869803	PATU8988S	viability after 35 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	1.1289782132424797	[753]	[727,599,NaN]	9	hSpCas9	negative selection	9831415
194138189	194138212	3	-	27869803	PATU8988S	viability after 35 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.8526221853181188	[446]	[365,283,NaN]	8	hSpCas9	negative selection	9831416
194136434	194136457	3	+	27869803	PATU8988S	viability after 31 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.8306007555418966	[1109]	[692,906,NaN]	8	hSpCas9	negative selection	9913860
194136436	194136459	3	-	27869803	PATU8988S	viability after 31 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	0.45578523385123404	[466]	[239,274,NaN]	5	hSpCas9	negative selection	9913861
194136960	194136983	3	+	27869803	PATU8988S	viability after 31 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	0.16697249863345154	[757]	[403,256,NaN]	2	hSpCas9	negative selection	9913862
194137729	194137752	3	+	27869803	PATU8988S	viability after 31 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	0.5947743986264898	[936]	[459,696,NaN]	7	hSpCas9	negative selection	9913863
194137756	194137779	3	-	27869803	PATU8988S	viability after 31 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	0.9628926518133726	[753]	[567,608,NaN]	9	hSpCas9	negative selection	9913864
194138189	194138212	3	-	27869803	PATU8988S	viability after 31 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.9571912991803131	[446]	[221,503,NaN]	9	hSpCas9	negative selection	9913865
194136434	194136457	3	+	27869803	HPAFII	viability after 35 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	0.5371997014135124	[529]	[402,373,NaN]	3	hSpCas9	negative selection	9996309
194136436	194136459	3	-	27869803	HPAFII	viability after 35 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-2.884607205290278	[168]	[4,18,NaN]	-8	hSpCas9	negative selection	9996310
194136960	194136983	3	+	27869803	HPAFII	viability after 35 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.5121400284616453	[290]	[53,48,NaN]	-7	hSpCas9	negative selection	9996311
194137729	194137752	3	+	27869803	HPAFII	viability after 35 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-1.2924807427602327	[297]	[62,59,NaN]	-6	hSpCas9	negative selection	9996312
194137756	194137779	3	-	27869803	HPAFII	viability after 35 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-1.2898238058753972	[425]	[27,155,NaN]	-6	hSpCas9	negative selection	9996313
194138189	194138212	3	-	27869803	HPAFII	viability after 35 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	0.004691598870785574	[200]	[158,37,NaN]	0	hSpCas9	negative selection	9996314
194136434	194136457	3	+	27869803	HPAFII	viability after 31 days	AGCCAGTGTCAACACGACACCGG	HES1	ENSG00000114315	-0.44461063112804666	[529]	[230,204,NaN]	-3	hSpCas9	negative selection	10078758
194136436	194136459	3	-	27869803	HPAFII	viability after 31 days	ATCCGGTGTCGTGTTGACACTGG	HES1	ENSG00000114315	-2.1431619596355285	[168]	[31,9,NaN]	-8	hSpCas9	negative selection	10078759
194136960	194136983	3	+	27869803	HPAFII	viability after 31 days	GAGCTCGCGGCATTCCAAGCTGG	HES1	ENSG00000114315	-1.7242308376539057	[290]	[58,38,NaN]	-7	hSpCas9	negative selection	10078760
194137729	194137752	3	+	27869803	HPAFII	viability after 31 days	CTTCAGCGAGTGCATGAACGAGG	HES1	ENSG00000114315	-0.20759488914239355	[297]	[140,148,NaN]	-1	hSpCas9	negative selection	10078761
194137756	194137779	3	-	27869803	HPAFII	viability after 31 days	CCTCGCACGTGGACAGGAAGCGG	HES1	ENSG00000114315	-1.7979007295306746	[425]	[40,98,NaN]	-7	hSpCas9	negative selection	10078762
194138189	194138212	3	-	27869803	HPAFII	viability after 31 days	ATGGAGTCCGCCGTAAGCGAGGG	HES1	ENSG00000114315	-0.18499681306654575	[200]	[148,44,NaN]	-1	hSpCas9	negative selection	10078763
194136415	194136438	3	-	28162770	P31FUJ	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.32253236507039096	[198]	[186]	-3	hSpCas9	negative selection	10168442
194137940	194137963	3	-	28162770	P31FUJ	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	-1.706733392746791	[49]	[17]	-8	hSpCas9	negative selection	10168443
194137013	194137036	3	+	28162770	P31FUJ	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.5496063605129948	[49]	[85]	6	hSpCas9	negative selection	10168444
194136966	194136989	3	+	28162770	P31FUJ	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	1.5152185782608232	[38]	[130]	9	hSpCas9	negative selection	10168445
194136431	194136454	3	-	28162770	P31FUJ	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.6276891359453096	[395]	[718]	7	hSpCas9	negative selection	10168446
194136613	194136636	3	+	28162770	P31FUJ	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.7613999510475086	[373]	[744]	8	hSpCas9	negative selection	10168447
194136467	194136490	3	+	28162770	P31FUJ	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.5274785565193084	[355]	[602]	6	hSpCas9	negative selection	10168448
194136947	194136970	3	+	28162770	P31FUJ	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.09274750445524194	[556]	[697]	0	hSpCas9	negative selection	10168449
194137026	194137049	3	+	28162770	P31FUJ	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.42616087775055467	[113]	[179]	5	hSpCas9	negative selection	10168450
194137001	194137024	3	+	28162770	P31FUJ	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.12677614132214954	[589]	[756]	1	hSpCas9	negative selection	10168451
194136415	194136438	3	-	28162770	TF1	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10337808
194137940	194137963	3	-	28162770	TF1	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10337809
194137013	194137036	3	+	28162770	TF1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337810
194136966	194136989	3	+	28162770	TF1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337811
194136431	194136454	3	-	28162770	TF1	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	NaN	[NaN]	[565]	1	hSpCas9	negative selection	10337812
194136613	194136636	3	+	28162770	TF1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	NaN	[NaN]	[686]	1	hSpCas9	negative selection	10337813
194136467	194136490	3	+	28162770	TF1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10337814
194136947	194136970	3	+	28162770	TF1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10337815
194137026	194137049	3	+	28162770	TF1	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10337816
194137001	194137024	3	+	28162770	TF1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10337817
194136415	194136438	3	-	28162770	SKM1	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.19815018390725428	[60]	[93]	-2	hSpCas9	negative selection	10507174
194137940	194137963	3	-	28162770	SKM1	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	-1.5000736031346436	[7]	[4]	-7	hSpCas9	negative selection	10507175
194137013	194137036	3	+	28162770	SKM1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10507176
194136966	194136989	3	+	28162770	SKM1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.7629608026991503	[17]	[53]	7	hSpCas9	negative selection	10507177
194136431	194136454	3	-	28162770	SKM1	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.41195547494736484	[141]	[333]	4	hSpCas9	negative selection	10507178
194136613	194136636	3	+	28162770	SKM1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.7794489254877195	[115]	[351]	7	hSpCas9	negative selection	10507179
194136467	194136490	3	+	28162770	SKM1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.25722499312856956	[61]	[130]	2	hSpCas9	negative selection	10507180
194136947	194136970	3	+	28162770	SKM1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.3155018257279295	[109]	[241]	3	hSpCas9	negative selection	10507181
194137026	194137049	3	+	28162770	SKM1	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-0.1845717774067137	[26]	[41]	-1	hSpCas9	negative selection	10507182
194137001	194137024	3	+	28162770	SKM1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.2621926745291876	[134]	[198]	-2	hSpCas9	negative selection	10507183
194136415	194136438	3	-	28162770	SKM1	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.19815018390725428	[60]	[93]	-2	hSpCas9	negative selection	10676540
194137940	194137963	3	-	28162770	SKM1	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	-1.5000736031346436	[7]	[4]	-7	hSpCas9	negative selection	10676541
194137013	194137036	3	+	28162770	SKM1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10676542
194136966	194136989	3	+	28162770	SKM1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.7629608026991503	[17]	[53]	7	hSpCas9	negative selection	10676543
194136431	194136454	3	-	28162770	SKM1	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.41195547494736484	[141]	[333]	4	hSpCas9	negative selection	10676544
194136613	194136636	3	+	28162770	SKM1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.7794489254877195	[115]	[351]	7	hSpCas9	negative selection	10676545
194136467	194136490	3	+	28162770	SKM1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.25722499312856956	[61]	[130]	2	hSpCas9	negative selection	10676546
194136947	194136970	3	+	28162770	SKM1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.3155018257279295	[109]	[241]	3	hSpCas9	negative selection	10676547
194137026	194137049	3	+	28162770	SKM1	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-0.1845717774067137	[26]	[41]	-1	hSpCas9	negative selection	10676548
194137001	194137024	3	+	28162770	SKM1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.2621926745291876	[134]	[198]	-2	hSpCas9	negative selection	10676549
194136415	194136438	3	-	28162770	PL21	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.4678786259593945	[142]	[44]	-3	hSpCas9	negative selection	10845906
194137940	194137963	3	-	28162770	PL21	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	1.2996752880402345	[41]	[44]	9	hSpCas9	negative selection	10845907
194137013	194137036	3	+	28162770	PL21	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.29324901888080146	[74]	[39]	2	hSpCas9	negative selection	10845908
194136966	194136989	3	+	28162770	PL21	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-3.3848228862318366	[71]	[2]	-9	hSpCas9	negative selection	10845909
194136431	194136454	3	-	28162770	PL21	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.33020015505369305	[529]	[289]	3	hSpCas9	negative selection	10845910
194136613	194136636	3	+	28162770	PL21	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.1695728981934703	[476]	[466]	8	hSpCas9	negative selection	10845911
194136467	194136490	3	+	28162770	PL21	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.8988351917278092	[190]	[154]	7	hSpCas9	negative selection	10845912
194136947	194136970	3	+	28162770	PL21	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.6791297465573795	[352]	[245]	6	hSpCas9	negative selection	10845913
194137026	194137049	3	+	28162770	PL21	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.28867628909097753	[78]	[41]	2	hSpCas9	negative selection	10845914
194137001	194137024	3	+	28162770	PL21	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	1.3125019799452782	[320]	[346]	9	hSpCas9	negative selection	10845915
194136415	194136438	3	-	28162770	P31FUJ	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.32253236507039096	[198]	[186]	-3	hSpCas9	negative selection	11015272
194137940	194137963	3	-	28162770	P31FUJ	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	-1.706733392746791	[49]	[17]	-8	hSpCas9	negative selection	11015273
194137013	194137036	3	+	28162770	P31FUJ	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.5496063605129948	[49]	[85]	6	hSpCas9	negative selection	11015274
194136966	194136989	3	+	28162770	P31FUJ	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	1.5152185782608232	[38]	[130]	9	hSpCas9	negative selection	11015275
194136431	194136454	3	-	28162770	P31FUJ	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.6276891359453096	[395]	[718]	7	hSpCas9	negative selection	11015276
194136613	194136636	3	+	28162770	P31FUJ	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.7613999510475086	[373]	[744]	8	hSpCas9	negative selection	11015277
194136467	194136490	3	+	28162770	P31FUJ	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.5274785565193084	[355]	[602]	6	hSpCas9	negative selection	11015278
194136947	194136970	3	+	28162770	P31FUJ	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.09274750445524194	[556]	[697]	0	hSpCas9	negative selection	11015279
194137026	194137049	3	+	28162770	P31FUJ	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.42616087775055467	[113]	[179]	5	hSpCas9	negative selection	11015280
194137001	194137024	3	+	28162770	P31FUJ	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.12677614132214954	[589]	[756]	1	hSpCas9	negative selection	11015281
194136415	194136438	3	-	28162770	OCIAML5	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.9279119122623021	[75]	[260]	7	hSpCas9	negative selection	11184638
194137940	194137963	3	-	28162770	OCIAML5	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.7556160063572426	[20]	[63]	6	hSpCas9	negative selection	11184639
194137013	194137036	3	+	28162770	OCIAML5	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.126559778343436	[33]	[66]	1	hSpCas9	negative selection	11184640
194136966	194136989	3	+	28162770	OCIAML5	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-0.20821038108927237	[15]	[24]	-1	hSpCas9	negative selection	11184641
194136431	194136454	3	-	28162770	OCIAML5	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.26129928215028286	[262]	[568]	2	hSpCas9	negative selection	11184642
194136613	194136636	3	+	28162770	OCIAML5	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.6473290740622637	[300]	[850]	5	hSpCas9	negative selection	11184643
194136467	194136490	3	+	28162770	OCIAML5	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.2708395766729799	[148]	[648]	9	hSpCas9	negative selection	11184644
194136947	194136970	3	+	28162770	OCIAML5	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.7672715094581744	[234]	[721]	6	hSpCas9	negative selection	11184645
194137026	194137049	3	+	28162770	OCIAML5	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.26082748554193647	[85]	[185]	2	hSpCas9	negative selection	11184646
194137001	194137024	3	+	28162770	OCIAML5	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.23509423017988196	[280]	[596]	2	hSpCas9	negative selection	11184647
194136415	194136438	3	-	28162770	EOL1	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.10354453545881837	[362]	[177]	-1	hSpCas9	negative selection	11354004
194137940	194137963	3	-	28162770	EOL1	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	1.0523033187689073	[53]	[58]	8	hSpCas9	negative selection	11354005
194137013	194137036	3	+	28162770	EOL1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.4925968893553442	[142]	[105]	4	hSpCas9	negative selection	11354006
194136966	194136989	3	+	28162770	EOL1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.46341385770223686	[105]	[76]	4	hSpCas9	negative selection	11354007
194136431	194136454	3	-	28162770	EOL1	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.03815188007739434	[829]	[448]	0	hSpCas9	negative selection	11354008
194136613	194136636	3	+	28162770	EOL1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.098356207500075	[741]	[836]	8	hSpCas9	negative selection	11354009
194136467	194136490	3	+	28162770	EOL1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.6895277419063374	[305]	[259]	6	hSpCas9	negative selection	11354010
194136947	194136970	3	+	28162770	EOL1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	1.2477691834794176	[445]	[557]	9	hSpCas9	negative selection	11354011
194137026	194137049	3	+	28162770	EOL1	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.24647586645789676	[87]	[54]	2	hSpCas9	negative selection	11354012
194137001	194137024	3	+	28162770	EOL1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.9508990985174867	[433]	[441]	7	hSpCas9	negative selection	11354013
194136415	194136438	3	-	28162770	MOLM13	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	1.0574246120555593	[209]	[315]	7	hSpCas9	negative selection	11523370
194137940	194137963	3	-	28162770	MOLM13	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	1.0084577629072817	[32]	[47]	7	hSpCas9	negative selection	11523371
194137013	194137036	3	+	28162770	MOLM13	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.5223371655669551	[103]	[107]	4	hSpCas9	negative selection	11523372
194136966	194136989	3	+	28162770	MOLM13	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.8215263361592793	[89]	[114]	6	hSpCas9	negative selection	11523373
194136431	194136454	3	-	28162770	MOLM13	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	1.2977899625186788	[516]	[918]	8	hSpCas9	negative selection	11523374
194136613	194136636	3	+	28162770	MOLM13	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.2396526469211915	[638]	[1090]	8	hSpCas9	negative selection	11523375
194136467	194136490	3	+	28162770	MOLM13	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	-0.1358378014537307	[502]	[330]	-1	hSpCas9	negative selection	11523376
194136947	194136970	3	+	28162770	MOLM13	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	1.08022832119704	[434]	[664]	7	hSpCas9	negative selection	11523377
194137026	194137049	3	+	28162770	MOLM13	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-3.5321106184554214	[127]	[7]	-8	hSpCas9	negative selection	11523378
194137001	194137024	3	+	28162770	MOLM13	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.3436166272468192	[520]	[477]	2	hSpCas9	negative selection	11523379
194136415	194136438	3	-	28162770	HEL	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	-0.2083977820851603	[183]	[101]	-1	hSpCas9	negative selection	11692736
194137940	194137963	3	-	28162770	HEL	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.043276761584085666	[49]	[32]	0	hSpCas9	negative selection	11692737
194137013	194137036	3	+	28162770	HEL	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	1.16630078805737	[95]	[137]	8	hSpCas9	negative selection	11692738
194136966	194136989	3	+	28162770	HEL	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-1.2152421631272154	[86]	[23]	-6	hSpCas9	negative selection	11692739
194136431	194136454	3	-	28162770	HEL	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	1.1974471170189203	[513]	[754]	9	hSpCas9	negative selection	11692740
194136613	194136636	3	+	28162770	HEL	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.7774391909288487	[561]	[616]	6	hSpCas9	negative selection	11692741
194136467	194136490	3	+	28162770	HEL	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	-0.586079858495524	[374]	[159]	-4	hSpCas9	negative selection	11692742
194136947	194136970	3	+	28162770	HEL	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.33118648987721444	[380]	[306]	2	hSpCas9	negative selection	11692743
194137026	194137049	3	+	28162770	HEL	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-0.2052580745545931	[134]	[74]	-1	hSpCas9	negative selection	11692744
194137001	194137024	3	+	28162770	HEL	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	-0.27373781243735973	[452]	[239]	-2	hSpCas9	negative selection	11692745
194136415	194136438	3	-	28162770	MV411	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.9512362810137823	[131]	[214]	8	hSpCas9	negative selection	11862102
194137940	194137963	3	-	28162770	MV411	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.6373840690987884	[28]	[37]	6	hSpCas9	negative selection	11862103
194137013	194137036	3	+	28162770	MV411	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.24743755078277507	[39]	[39]	2	hSpCas9	negative selection	11862104
194136966	194136989	3	+	28162770	MV411	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.16497539059080224	[53]	[50]	1	hSpCas9	negative selection	11862105
194136431	194136454	3	-	28162770	MV411	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.3863356566044631	[375]	[413]	3	hSpCas9	negative selection	11862106
194136613	194136636	3	+	28162770	MV411	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	1.0161972275278015	[367]	[626]	8	hSpCas9	negative selection	11862107
194136467	194136490	3	+	28162770	MV411	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	-0.030297904397447672	[216]	[178]	0	hSpCas9	negative selection	11862108
194136947	194136970	3	+	28162770	MV411	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.4868030507229367	[337]	[398]	4	hSpCas9	negative selection	11862109
194137026	194137049	3	+	28162770	MV411	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.07497035477800962	[70]	[62]	0	hSpCas9	negative selection	11862110
194137001	194137024	3	+	28162770	MV411	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.7233572922086414	[347]	[483]	6	hSpCas9	negative selection	11862111
194136415	194136438	3	-	28162770	MONOMAC1	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.3609586060613331	[107]	[158]	3	hSpCas9	negative selection	12031468
194137940	194137963	3	-	28162770	MONOMAC1	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.5228552337477108	[16]	[27]	5	hSpCas9	negative selection	12031469
194137013	194137036	3	+	28162770	MONOMAC1	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	0.636953201501517	[45]	[81]	6	hSpCas9	negative selection	12031470
194136966	194136989	3	+	28162770	MONOMAC1	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	-1.5506738016742538	[22]	[8]	-8	hSpCas9	negative selection	12031471
194136431	194136454	3	-	28162770	MONOMAC1	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.039696597343915174	[285]	[336]	0	hSpCas9	negative selection	12031472
194136613	194136636	3	+	28162770	MONOMAC1	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	-0.15944006040190195	[302]	[310]	-1	hSpCas9	negative selection	12031473
194136467	194136490	3	+	28162770	MONOMAC1	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	-0.5046096489698461	[124]	[100]	-4	hSpCas9	negative selection	12031474
194136947	194136970	3	+	28162770	MONOMAC1	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	0.13473157045536177	[262]	[330]	1	hSpCas9	negative selection	12031475
194137026	194137049	3	+	28162770	MONOMAC1	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	1.1833868971379533	[57]	[150]	8	hSpCas9	negative selection	12031476
194137001	194137024	3	+	28162770	MONOMAC1	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.49539035103015383	[249]	[403]	5	hSpCas9	negative selection	12031477
194136415	194136438	3	-	28162770	OCIAML2	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.12160067594303409	[32]	[198]	1	hSpCas9	negative selection	12200834
194137940	194137963	3	-	28162770	OCIAML2	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	0.43626077036635724	[5]	[44]	4	hSpCas9	negative selection	12200835
194137013	194137036	3	+	28162770	OCIAML2	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	1.073690690981649	[5]	[69]	8	hSpCas9	negative selection	12200836
194136966	194136989	3	+	28162770	OCIAML2	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.18648246123483014	[12]	[81]	1	hSpCas9	negative selection	12200837
194136431	194136454	3	-	28162770	OCIAML2	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	0.5976110360706601	[79]	[670]	6	hSpCas9	negative selection	12200838
194136613	194136636	3	+	28162770	OCIAML2	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.42078936160391756	[99]	[741]	4	hSpCas9	negative selection	12200839
194136467	194136490	3	+	28162770	OCIAML2	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	0.3599574030531599	[43]	[312]	3	hSpCas9	negative selection	12200840
194136947	194136970	3	+	28162770	OCIAML2	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.003930206140824843	[71]	[397]	0	hSpCas9	negative selection	12200841
194137026	194137049	3	+	28162770	OCIAML2	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	0.6090973672285731	[10]	[92]	6	hSpCas9	negative selection	12200842
194137001	194137024	3	+	28162770	OCIAML2	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.0834717117742344	[62]	[369]	0	hSpCas9	negative selection	12200843
194136415	194136438	3	-	28162770	OCIAML3	viability	GGCTGGGGTAGCAGCCACCGGGG	HES1	ENSG00000114315	0.1284583841469279	[49]	[164]	1	hSpCas9	negative selection	12370200
194137940	194137963	3	-	28162770	OCIAML3	viability	GGGATGGGCACGAGTGGCGGCGG	HES1	ENSG00000114315	1.0498485494505616	[7]	[49]	8	hSpCas9	negative selection	12370201
194137013	194137036	3	+	28162770	OCIAML3	viability	AGCACCTCCGGAACCTGCAGCGG	HES1	ENSG00000114315	1.2864107439231642	[10]	[80]	9	hSpCas9	negative selection	12370202
194136966	194136989	3	+	28162770	OCIAML3	viability	GCGGCATTCCAAGCTGGAGAAGG	HES1	ENSG00000114315	0.32160017238546446	[21]	[82]	3	hSpCas9	negative selection	12370203
194136431	194136454	3	-	28162770	OCIAML3	viability	GTGTCGTGTTGACACTGGCTGGG	HES1	ENSG00000114315	1.2781787317978577	[114]	[841]	9	hSpCas9	negative selection	12370204
194136613	194136636	3	+	28162770	OCIAML3	viability	GCAGTCATCAAAGCCTATTATGG	HES1	ENSG00000114315	0.8689017502846508	[112]	[622]	7	hSpCas9	negative selection	12370205
194136467	194136490	3	+	28162770	OCIAML3	viability	GACAGCATCTGAGCACAGAAAGG	HES1	ENSG00000114315	1.5824454041156468	[48]	[442]	9	hSpCas9	negative selection	12370206
194136947	194136970	3	+	28162770	OCIAML3	viability	CCTACTCTATGCAGAGCTCGCGG	HES1	ENSG00000114315	-0.0638810056831074	[142]	[412]	0	hSpCas9	negative selection	12370207
194137026	194137049	3	+	28162770	OCIAML3	viability	CCTGCAGCGGGCGCAGATGACGG	HES1	ENSG00000114315	-1.1283440679753516	[41]	[57]	-7	hSpCas9	negative selection	12370208
194137001	194137024	3	+	28162770	OCIAML3	viability	AAATGACAGTGAAGCACCTCCGG	HES1	ENSG00000114315	0.19419618138852934	[129]	[448]	1	hSpCas9	negative selection	12370209