Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 54626
• Symbol: HES2
• Description: hes family bHLH transcription factor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HES2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
6419684	6419707	1	-	26472758	Jiyoye	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	1.637042923404468	[54]	[128]	8	hSpCas9	negative selection	70296
6419803	6419826	1	-	26472758	Jiyoye	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.019104929827299028	[105]	[80]	0	hSpCas9	negative selection	70297
6419313	6419336	1	-	26472758	Jiyoye	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	2.366533397008528	[8]	[34]	9	hSpCas9	negative selection	70298
6419654	6419677	1	+	26472758	Jiyoye	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.1571971284975258	[21]	[36]	7	hSpCas9	negative selection	70299
6419301	6419324	1	-	26472758	Jiyoye	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.09523137519113326	[143]	[115]	0	hSpCas9	negative selection	70300
6419249	6419272	1	+	26472758	Jiyoye	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.5930419268172074	[159]	[181]	4	hSpCas9	negative selection	70301
6419602	6419625	1	+	26472758	Jiyoye	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.1103591916949922	[208]	[145]	-1	hSpCas9	negative selection	70302
6419277	6419300	1	-	26472758	Jiyoye	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	2.4250972895031357	[19]	[80]	9	hSpCas9	negative selection	70303
6419262	6419285	1	+	26472758	Jiyoye	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.6197200168859741	[62]	[72]	4	hSpCas9	negative selection	70304
6419233	6419256	1	+	26472758	Jiyoye	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	2.4071753815058736	[10]	[43]	9	hSpCas9	negative selection	70305
6419684	6419707	1	-	26472758	KBM7	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.08834841320584319	[821,622]	[360,354]	0	hSpCas9	negative selection	261414
6419803	6419826	1	-	26472758	KBM7	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.8373492091328973	[324,271]	[188,303]	8	hSpCas9	negative selection	261415
6419313	6419336	1	-	26472758	KBM7	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.3792721627901049	[483,487]	[249,110]	-3	hSpCas9	negative selection	261416
6419654	6419677	1	+	26472758	KBM7	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.2725413302733752	[158,119]	[100,206]	9	hSpCas9	negative selection	261417
6419301	6419324	1	-	26472758	KBM7	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.12376866315027857	[580,494]	[317,235]	1	hSpCas9	negative selection	261418
6419249	6419272	1	+	26472758	KBM7	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.4100157305502712	[744,672]	[559,337]	4	hSpCas9	negative selection	261419
6419602	6419625	1	+	26472758	KBM7	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.29623342717011786	[487,398]	[307,206]	3	hSpCas9	negative selection	261420
6419277	6419300	1	-	26472758	KBM7	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.9391458386526599	[299,320]	[267,294]	8	hSpCas9	negative selection	261421
6419262	6419285	1	+	26472758	KBM7	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.8708120845960488	[358,399]	[410,256]	8	hSpCas9	negative selection	261422
6419233	6419256	1	+	26472758	KBM7	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.5088100487274332	[173,111]	[55,127]	5	hSpCas9	negative selection	261423
6419684	6419707	1	-	26472758	Raji	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.2818240179384049	[318]	[89]	2	hSpCas9	negative selection	452532
6419803	6419826	1	-	26472758	Raji	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.9350679865062931	[150]	[66]	8	hSpCas9	negative selection	452533
6419313	6419336	1	-	26472758	Raji	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.5096537385785653	[226]	[74]	5	hSpCas9	negative selection	452534
6419654	6419677	1	+	26472758	Raji	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.3000286133159955	[41]	[11]	3	hSpCas9	negative selection	452535
6419301	6419324	1	-	26472758	Raji	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	1.5608951824670791	[110]	[75]	9	hSpCas9	negative selection	452536
6419249	6419272	1	+	26472758	Raji	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	-0.19217674648530825	[255]	[51]	-2	hSpCas9	negative selection	452537
6419602	6419625	1	+	26472758	Raji	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.07018491741935001	[274]	[66]	0	hSpCas9	negative selection	452538
6419277	6419300	1	-	26472758	Raji	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	-0.25826593694308075	[133]	[25]	-2	hSpCas9	negative selection	452539
6419262	6419285	1	+	26472758	Raji	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.042730577031346015	[250]	[59]	0	hSpCas9	negative selection	452540
6419233	6419256	1	+	26472758	Raji	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	1.1073835353735995	[117]	[58]	8	hSpCas9	negative selection	452541
6419684	6419707	1	-	26472758	K562	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.8069818434310385	[475]	[702]	6	hSpCas9	negative selection	643650
6419803	6419826	1	-	26472758	K562	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	1.135894270888278	[206]	[383]	8	hSpCas9	negative selection	643651
6419313	6419336	1	-	26472758	K562	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.5693624635505902	[449]	[255]	-4	hSpCas9	negative selection	643652
6419654	6419677	1	+	26472758	K562	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.300452762580775	[100]	[209]	9	hSpCas9	negative selection	643653
6419301	6419324	1	-	26472758	K562	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	-0.8003997761753989	[424]	[205]	-5	hSpCas9	negative selection	643654
6419249	6419272	1	+	26472758	K562	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.7444598745848281	[448]	[634]	6	hSpCas9	negative selection	643655
6419602	6419625	1	+	26472758	K562	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.4997645996685388	[438]	[523]	4	hSpCas9	negative selection	643656
6419277	6419300	1	-	26472758	K562	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.8379432418910272	[223]	[337]	7	hSpCas9	negative selection	643657
6419262	6419285	1	+	26472758	K562	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	-0.045800507493577336	[224]	[183]	0	hSpCas9	negative selection	643658
6419233	6419256	1	+	26472758	K562	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	1.384348988810922	[107]	[237]	9	hSpCas9	negative selection	643659
6419031	6419054	1	+	26627737	DLD1	viability	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.4510398119724776	[517]	[180,199,273]	4	hSpCas9	negative selection	772363
6419129	6419152	1	+	26627737	DLD1	viability	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.7542018413156821	[221]	[107,192,61]	7	hSpCas9	negative selection	772364
6419129	6419152	1	-	26627737	DLD1	viability	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.6956979375636612	[566]	[427,321,135]	7	hSpCas9	negative selection	772365
6419222	6419245	1	+	26627737	DLD1	viability	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.25567446038558417	[676]	[316,138,290]	2	hSpCas9	negative selection	772366
6419654	6419677	1	+	26627737	DLD1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.14502069883569688	[415]	[92,131,126]	-1	hSpCas9	negative selection	772367
6419031	6419054	1	+	26627737	GBM cells	viability after 5 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.003349323418517458	[213]	[137,90]	0	hSpCas9	negative selection	854678
6419129	6419152	1	+	26627737	GBM cells	viability after 5 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.1973014403736174	[154]	[74,69]	-3	hSpCas9	negative selection	854679
6419129	6419152	1	-	26627737	GBM cells	viability after 5 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.04764686615285396	[317]	[155,173]	0	hSpCas9	negative selection	854680
6419222	6419245	1	+	26627737	GBM cells	viability after 5 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	1.263910691664934	[32]	[41,42]	9	hSpCas9	negative selection	854681
6419654	6419677	1	+	26627737	GBM cells	viability after 5 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.2098429708237908	[78]	[89,105]	9	hSpCas9	negative selection	854682
6419031	6419054	1	+	26627737	GBM cells	viability after 13 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.005503940535103752	[213]	[145,90]	0	hSpCas9	negative selection	936993
6419129	6419152	1	+	26627737	GBM cells	viability after 13 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.20326449747549608	[154]	[87,103]	2	hSpCas9	negative selection	936994
6419129	6419152	1	-	26627737	GBM cells	viability after 13 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.11589674433785832	[317]	[188,134]	-1	hSpCas9	negative selection	936995
6419222	6419245	1	+	26627737	GBM cells	viability after 13 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.45111931810991823	[32]	[13,32]	6	hSpCas9	negative selection	936996
6419654	6419677	1	+	26627737	GBM cells	viability after 13 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.2211173698057587	[78]	[89,107]	9	hSpCas9	negative selection	936997
6419031	6419054	1	+	26627737	GBM cells	viability after 21 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.5513784241987012	[213]	[94,64]	-5	hSpCas9	negative selection	1019308
6419129	6419152	1	+	26627737	GBM cells	viability after 21 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.5085929922428444	[154]	[100,136]	5	hSpCas9	negative selection	1019309
6419129	6419152	1	-	26627737	GBM cells	viability after 21 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.4026989994529283	[317]	[230,225]	4	hSpCas9	negative selection	1019310
6419222	6419245	1	+	26627737	GBM cells	viability after 21 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.6743428008854737	[32]	[25,30]	6	hSpCas9	negative selection	1019311
6419654	6419677	1	+	26627737	GBM cells	viability after 21 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.1200859064010351	[78]	[109,77]	9	hSpCas9	negative selection	1019312
6419031	6419054	1	+	26627737	RPE1	viability after 9 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.11686900267607742	[1062]	[359,361]	0	hSpCas9	negative selection	1101623
6419129	6419152	1	+	26627737	RPE1	viability after 9 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.1434483650402779	[692]	[157,245]	-1	hSpCas9	negative selection	1101624
6419129	6419152	1	-	26627737	RPE1	viability after 9 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.6416702116762952	[842]	[347,493]	4	hSpCas9	negative selection	1101625
6419222	6419245	1	+	26627737	RPE1	viability after 9 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-1.3944693746527386	[1192]	[145,136]	-7	hSpCas9	negative selection	1101626
6419654	6419677	1	+	26627737	RPE1	viability after 9 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.6837053116416032	[367]	[119,268]	4	hSpCas9	negative selection	1101627
6419031	6419054	1	+	26627737	RPE1	viability after 12 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.23989071862907368	[1062]	[396,273]	1	hSpCas9	negative selection	1183938
6419129	6419152	1	+	26627737	RPE1	viability after 12 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.5731679929205067	[692]	[112,137]	-4	hSpCas9	negative selection	1183939
6419129	6419152	1	-	26627737	RPE1	viability after 12 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.5173357224570069	[842]	[312,335]	3	hSpCas9	negative selection	1183940
6419222	6419245	1	+	26627737	RPE1	viability after 12 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.5577853329506581	[1192]	[157,280]	-4	hSpCas9	negative selection	1183941
6419654	6419677	1	+	26627737	RPE1	viability after 12 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.1099658215531876	[367]	[192,234]	6	hSpCas9	negative selection	1183942
6419031	6419054	1	+	26627737	RPE1	viability after 15 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.3106535321578577	[1062]	[628,125]	2	hSpCas9	negative selection	1266253
6419129	6419152	1	+	26627737	RPE1	viability after 15 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.519840159216578	[692]	[95,175]	-3	hSpCas9	negative selection	1266254
6419129	6419152	1	-	26627737	RPE1	viability after 15 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.649463953181846	[842]	[370,376]	4	hSpCas9	negative selection	1266255
6419222	6419245	1	+	26627737	RPE1	viability after 15 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.016414420472537827	[1192]	[434,250]	0	hSpCas9	negative selection	1266256
6419654	6419677	1	+	26627737	RPE1	viability after 15 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.5931194816629228	[367]	[126,185]	4	hSpCas9	negative selection	1266257
6419031	6419054	1	+	26627737	RPE1	viability after 18 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.051856068115006315	[1062]	[278,316]	0	hSpCas9	negative selection	1348568
6419129	6419152	1	+	26627737	RPE1	viability after 18 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.6800720392537617	[692]	[64,171]	-4	hSpCas9	negative selection	1348569
6419129	6419152	1	-	26627737	RPE1	viability after 18 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.05019653675885187	[842]	[207,264]	0	hSpCas9	negative selection	1348570
6419222	6419245	1	+	26627737	RPE1	viability after 18 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.17373438828847532	[1192]	[224,349]	-1	hSpCas9	negative selection	1348571
6419654	6419677	1	+	26627737	RPE1	viability after 18 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.1552458745425558	[367]	[182,261]	6	hSpCas9	negative selection	1348572
6419031	6419054	1	+	26627737	HeLa	viability after 8 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.26106159604902157	[484]	[368,28,172]	-3	hSpCas9	negative selection	1430883
6419129	6419152	1	+	26627737	HeLa	viability after 8 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.18967436590116327	[289]	[165,50,125]	-2	hSpCas9	negative selection	1430884
6419129	6419152	1	-	26627737	HeLa	viability after 8 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.9829107384519333	[1017]	[294,198,195]	-7	hSpCas9	negative selection	1430885
6419222	6419245	1	+	26627737	HeLa	viability after 8 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.24732033273349885	[749]	[293,259,274]	-2	hSpCas9	negative selection	1430886
6419654	6419677	1	+	26627737	HeLa	viability after 8 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.3180565873719605	[170]	[50,123,93]	3	hSpCas9	negative selection	1430887
6419031	6419054	1	+	26627737	HeLa	viability after 12 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.111891238473873	[484]	[24,69,468]	-1	hSpCas9	negative selection	1513198
6419129	6419152	1	+	26627737	HeLa	viability after 12 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.5357443531349638	[289]	[184,93,250]	4	hSpCas9	negative selection	1513199
6419129	6419152	1	-	26627737	HeLa	viability after 12 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-1.062118138975937	[1017]	[299,213,91]	-7	hSpCas9	negative selection	1513200
6419222	6419245	1	+	26627737	HeLa	viability after 12 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.03201281156565661	[749]	[482,170,316]	0	hSpCas9	negative selection	1513201
6419654	6419677	1	+	26627737	HeLa	viability after 12 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.1564562125540283	[170]	[78,90,64]	1	hSpCas9	negative selection	1513202
6419031	6419054	1	+	26627737	HeLa	viability after 15 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.09352473126444022	[484]	[141,133,368]	0	hSpCas9	negative selection	1595513
6419129	6419152	1	+	26627737	HeLa	viability after 15 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.5246537438536886	[289]	[174,157,176]	4	hSpCas9	negative selection	1595514
6419129	6419152	1	-	26627737	HeLa	viability after 15 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-1.0883417718284742	[1017]	[271,185,119]	-7	hSpCas9	negative selection	1595515
6419222	6419245	1	+	26627737	HeLa	viability after 15 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.00798289900549698	[749]	[398,308,203]	0	hSpCas9	negative selection	1595516
6419654	6419677	1	+	26627737	HeLa	viability after 15 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.4064842416083888	[170]	[118,94,59]	3	hSpCas9	negative selection	1595517
6419031	6419054	1	+	26627737	HeLa	viability after 18 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.13639041273111763	[484]	[101,117,368]	1	hSpCas9	negative selection	1677828
6419129	6419152	1	+	26627737	HeLa	viability after 18 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.4871301842147518	[289]	[111,126,176]	4	hSpCas9	negative selection	1677829
6419129	6419152	1	-	26627737	HeLa	viability after 18 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-1.0706171216026723	[1017]	[187,152,119]	-7	hSpCas9	negative selection	1677830
6419222	6419245	1	+	26627737	HeLa	viability after 18 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.022873701470224606	[749]	[276,251,203]	0	hSpCas9	negative selection	1677831
6419654	6419677	1	+	26627737	HeLa	viability after 18 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.44788308823688006	[170]	[87,74,59]	3	hSpCas9	negative selection	1677832
6419031	6419054	1	+	26627737	HCT116	viability after 6 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-1.1172292044201337	[920]	[136,27]	-6	hSpCas9	negative selection	1760143
6419129	6419152	1	+	26627737	HCT116	viability after 6 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	2.2140258574406655	[182]	[59,173]	9	hSpCas9	negative selection	1760144
6419129	6419152	1	-	26627737	HCT116	viability after 6 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.38649707711013204	[1196]	[161,133]	-2	hSpCas9	negative selection	1760145
6419222	6419245	1	+	26627737	HCT116	viability after 6 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.7991639346810926	[1439]	[206,496]	4	hSpCas9	negative selection	1760146
6419654	6419677	1	+	26627737	HCT116	viability after 6 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.09384399496309359	[415]	[117,29]	0	hSpCas9	negative selection	1760147
6419031	6419054	1	+	26627737	HCT116	viability after 8 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.39912934611429074	[356]	[120,92,231]	-5	hSpCas9	negative selection	1842458
6419129	6419152	1	+	26627737	HCT116	viability after 8 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.5461000725060404	[272]	[104,91,111]	-6	hSpCas9	negative selection	1842459
6419129	6419152	1	-	26627737	HCT116	viability after 8 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.07772421901624132	[379]	[197,180,215]	-1	hSpCas9	negative selection	1842460
6419222	6419245	1	+	26627737	HCT116	viability after 8 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.5519360763252332	[654]	[335,226,177]	-6	hSpCas9	negative selection	1842461
6419654	6419677	1	+	26627737	HCT116	viability after 8 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.5077813122623605	[243]	[71,93,116]	-6	hSpCas9	negative selection	1842462
6419031	6419054	1	+	26627737	HCT116	viability after 9 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.0602508185453543	[920]	[260,215]	0	hSpCas9	negative selection	1924773
6419129	6419152	1	+	26627737	HCT116	viability after 9 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.9934842095985829	[182]	[84,106]	6	hSpCas9	negative selection	1924774
6419129	6419152	1	-	26627737	HCT116	viability after 9 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.9851894689081928	[1196]	[199,130]	-6	hSpCas9	negative selection	1924775
6419222	6419245	1	+	26627737	HCT116	viability after 9 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.7927987384965537	[1439]	[231,213]	-5	hSpCas9	negative selection	1924776
6419654	6419677	1	+	26627737	HCT116	viability after 9 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-2.4859223432461723	[415]	[30,10]	-9	hSpCas9	negative selection	1924777
6419031	6419054	1	+	26627737	HCT116	viability after 12 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.029005719069008118	[356]	[137,192,247]	0	hSpCas9	negative selection	2007088
6419129	6419152	1	+	26627737	HCT116	viability after 12 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.49380090921450437	[272]	[82,88,134]	-5	hSpCas9	negative selection	2007089
6419129	6419152	1	-	26627737	HCT116	viability after 12 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.2076173285292799	[379]	[144,174,377]	2	hSpCas9	negative selection	2007090
6419222	6419245	1	+	26627737	HCT116	viability after 12 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.23830329814391316	[654]	[266,307,302]	-2	hSpCas9	negative selection	2007091
6419654	6419677	1	+	26627737	HCT116	viability after 12 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.20704580084107876	[243]	[153,90,83]	-2	hSpCas9	negative selection	2007092
6419031	6419054	1	+	26627737	HCT116	viability after 15 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.0600817658626735	[356]	[109,254,262]	0	hSpCas9	negative selection	2089403
6419129	6419152	1	+	26627737	HCT116	viability after 15 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.977401234538919	[272]	[33,91,106]	-7	hSpCas9	negative selection	2089404
6419129	6419152	1	-	26627737	HCT116	viability after 15 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.36558357655968826	[379]	[396,211,248]	3	hSpCas9	negative selection	2089405
6419222	6419245	1	+	26627737	HCT116	viability after 15 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.23618069592150348	[654]	[318,399,239]	-2	hSpCas9	negative selection	2089406
6419654	6419677	1	+	26627737	HCT116	viability after 15 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.41655252932492765	[243]	[132,49,134]	-4	hSpCas9	negative selection	2089407
6419031	6419054	1	+	26627737	HCT116	viability after 18 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.25567074074722224	[356]	[22,148,266]	-2	hSpCas9	negative selection	2171718
6419129	6419152	1	+	26627737	HCT116	viability after 18 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.8450836965872207	[272]	[59,73,86]	-7	hSpCas9	negative selection	2171719
6419129	6419152	1	-	26627737	HCT116	viability after 18 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.39377114059110757	[379]	[108,130,181]	-4	hSpCas9	negative selection	2171720
6419222	6419245	1	+	26627737	HCT116	viability after 18 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.2482950820743921	[654]	[595,254,280]	2	hSpCas9	negative selection	2171721
6419654	6419677	1	+	26627737	HCT116	viability after 18 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.04271397620745071	[243]	[120,90,133]	0	hSpCas9	negative selection	2171722
6419313	6419336	1	-	24336569	HL60	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.1273561013883093	[526]	[1020]	-1	hSpCas9	negative selection	2269454
6419602	6419625	1	+	24336569	HL60	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.13879727569484768	[307]	[591]	-1	hSpCas9	negative selection	2269455
6419609	6419632	1	-	24336569	HL60	viability	CATCCTGCCGCTGCTGGGCCGGG	HES2	ENSG00000069812	1.038375669377107	[126]	[551]	7	hSpCas9	negative selection	2269456
6419614	6419637	1	-	24336569	HL60	viability	GGGCTCATCCTGCCGCTGCTGGG	HES2	ENSG00000069812	1.8580926838999448	[130]	[1004]	9	hSpCas9	negative selection	2269457
6419635	6419658	1	-	24336569	HL60	viability	CAGAGCCTGAGCCAGCTTAAGGG	HES2	ENSG00000069812	1.2090143556334132	[370]	[1814]	8	hSpCas9	negative selection	2269458
6419654	6419677	1	+	24336569	HL60	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.33058954021112613	[362]	[965]	3	hSpCas9	negative selection	2269459
6419671	6419694	1	+	24336569	HL60	viability	CGCCGGCGCTTCTCCAGCAGCGG	HES2	ENSG00000069812	-1.5700221173969897	[368]	[262]	-8	hSpCas9	negative selection	2269460
6419678	6419701	1	+	24336569	HL60	viability	GCTTCTCCAGCAGCGGCTTCAGG	HES2	ENSG00000069812	-0.4195118608795356	[224]	[355]	-4	hSpCas9	negative selection	2269461
6419684	6419707	1	-	24336569	HL60	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	2.3640953434268437	[56]	[620]	9	hSpCas9	negative selection	2269462
6419772	6419795	1	-	24336569	HL60	viability	CGCGGCGGAGCTGCGCAAGGTGG	HES2	ENSG00000069812	5.3363884142570015	[1]	[170]	9	hSpCas9	negative selection	2269463
6419313	6419336	1	-	24336569	KBM7	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.8803731666318841	[435]	[645]	-6	hSpCas9	negative selection	2336631
6419602	6419625	1	+	24336569	KBM7	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-1.2058024112756076	[432]	[511]	-7	hSpCas9	negative selection	2336632
6419609	6419632	1	-	24336569	KBM7	viability	CATCCTGCCGCTGCTGGGCCGGG	HES2	ENSG00000069812	0.0988268929197888	[315]	[922]	0	hSpCas9	negative selection	2336633
6419614	6419637	1	-	24336569	KBM7	viability	GGGCTCATCCTGCCGCTGCTGGG	HES2	ENSG00000069812	0.6549905370916653	[189]	[815]	6	hSpCas9	negative selection	2336634
6419635	6419658	1	-	24336569	KBM7	viability	CAGAGCCTGAGCCAGCTTAAGGG	HES2	ENSG00000069812	0.5585210029875352	[589]	[2369]	5	hSpCas9	negative selection	2336635
6419654	6419677	1	+	24336569	KBM7	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.3638918339809536	[149]	[1052]	9	hSpCas9	negative selection	2336636
6419671	6419694	1	+	24336569	KBM7	viability	CGCCGGCGCTTCTCCAGCAGCGG	HES2	ENSG00000069812	0.4438629999709722	[168]	[626]	4	hSpCas9	negative selection	2336637
6419678	6419701	1	+	24336569	KBM7	viability	GCTTCTCCAGCAGCGGCTTCAGG	HES2	ENSG00000069812	-0.5942488456908919	[149]	[270]	-5	hSpCas9	negative selection	2336638
6419684	6419707	1	-	24336569	KBM7	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.8277621047365242	[106]	[517]	7	hSpCas9	negative selection	2336639
6419772	6419795	1	-	24336569	KBM7	viability	CGCGGCGGAGCTGCGCAAGGTGG	HES2	ENSG00000069812	1.3459699259836917	[14]	[103]	9	hSpCas9	negative selection	2336640
6420008	6420031	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCTGCGCAGGAACAAAGGCAGG	HES2	ENSG00000069812	1.3192660628190411	[64,428]	[31,250]	5	dCas9-VP64	positive selection	2451033
6420057	6420080	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGGAGCGGGATCCCCGGGGG	HES2	ENSG00000069812	1.5892983081677778	[16,11]	[1,16]	6	dCas9-VP64	positive selection	2451034
6420081	6420104	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGCGTCCTGTCTACCGCGGGG	HES2	ENSG00000069812	-1.4964389852247544	[150,52]	[10,3]	-8	dCas9-VP64	positive selection	2451035
6424616	6424639	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGGAGAGAAGCCCCTGGG	HES2	ENSG00000069812	-1.4509839394751767	[101,252]	[9,18]	-8	dCas9-VP64	positive selection	2458477
6424641	6424664	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACTCGTGCGACTGGGGCAAGG	HES2	ENSG00000069812	0.3659132944672273	[58,7]	[13,3]	1	dCas9-VP64	positive selection	2458478
6424592	6424615	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTCTCAACTGTTACGTGAGG	HES2	ENSG00000069812	1.2889341513006896	[45,8]	[2,26]	5	dCas9-VP64	positive selection	2458479
6420008	6420031	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCTGCGCAGGAACAAAGGCAGG	HES2	ENSG00000069812	-0.8971404875238792	[194,200]	[54,14]	-8	dCas9-VP64	positive selection	2546288
6420057	6420080	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGGAGCGGGATCCCCGGGGG	HES2	ENSG00000069812	-0.8907249447199805	[104,72]	[23,6]	-8	dCas9-VP64	positive selection	2546289
6420081	6420104	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGCGTCCTGTCTACCGCGGGG	HES2	ENSG00000069812	0.6132985863365424	[79,67]	[51,22]	4	dCas9-VP64	positive selection	2546290
6424616	6424639	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGGAGAGAAGCCCCTGGG	HES2	ENSG00000069812	-0.29295243765371415	[96,358]	[35,81]	-3	dCas9-VP64	positive selection	2553732
6424641	6424664	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACTCGTGCGACTGGGGCAAGG	HES2	ENSG00000069812	0.1187614271619275	[30,32]	[11,9]	1	dCas9-VP64	positive selection	2553733
6424592	6424615	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTCTCAACTGTTACGTGAGG	HES2	ENSG00000069812	-1.0295565982965815	[80,105]	[13,14]	-8	dCas9-VP64	positive selection	2553734
6419313	6419336	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.17026430789788605	[2,2]	[4,1]	3	hSpCas9	positive selection	2993090
6419273	6419296	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	0.16091146387820926	[3,3]	[2,3]	3	hSpCas9	positive selection	2993091
6419250	6419273	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	-0.3673847138440359	[3,3]	[3,0]	-5	hSpCas9	positive selection	2993092
6419787	6419810	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	-0.35909019336105963	[2,2]	[2,0]	-5	hSpCas9	positive selection	2993093
6419313	6419336	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.6855702531843622	[2,2]	[4,3]	9	hSpCas9	positive selection	3060948
6419273	6419296	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	-0.5415340760305316	[3,3]	[3,0]	-7	hSpCas9	positive selection	3060949
6419250	6419273	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	-0.02548577145719816	[3,3]	[3,1]	0	hSpCas9	positive selection	3060950
6419787	6419810	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	0.20461984562072583	[2,2]	[2,0]	3	hSpCas9	positive selection	3060951
6419314	6419337		+	24336571	A375	resistance to PLX after 7 days	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.24621229512569734	[11,11]	[13,12]	7	hSpCas9	positive selection	3118837
6419233	6419256		+	24336571	A375	resistance to PLX after 7 days	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.02128737732952403	[14,11]	[11,15]	0	hSpCas9	positive selection	3118838
6419654	6419677		+	24336571	A375	resistance to PLX after 7 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.16525992417799962	[15,11]	[11,12]	-5	hSpCas9	positive selection	3118839
6419314	6419337		+	24336571	A375	resistance to PLX after 14 days	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.48730027067489756	[13,12]	[2,4]	-6	hSpCas9	positive selection	3176630
6419233	6419256		+	24336571	A375	resistance to PLX after 14 days	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.11385616100714974	[22,11]	[9,7]	1	hSpCas9	positive selection	3176631
6419654	6419677		+	24336571	A375	resistance to PLX after 14 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.01185612970826061	[7,11]	[4,2]	0	hSpCas9	positive selection	3176632
6419314	6419337		+	24336571	A375	viability after 7 days	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.06289353490461233	[11]	[11,11]	0	hSpCas9	negative selection	3234423
6419233	6419256		+	24336571	A375	viability after 7 days	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.3942987701437931	[10]	[14,11]	6	hSpCas9	negative selection	3234424
6419654	6419677		+	24336571	A375	viability after 7 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.25537558587964404	[17]	[15,11]	-4	hSpCas9	negative selection	3234425
6419314	6419337		+	24336571	A375	viability after 14 days	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.2707489507465932	[11]	[13,12]	3	hSpCas9	negative selection	3292216
6419233	6419256		+	24336571	A375	viability after 14 days	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.761692040063155	[10]	[22,11]	8	hSpCas9	negative selection	3292217
6419654	6419677		+	24336571	A375	viability after 14 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.7188605748579252	[17]	[7,11]	-7	hSpCas9	negative selection	3292218
6419654	6419677	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.973859522024851	[30,46]	[0,0]	7	hSpCas9	positive selection	3353275
6419130	6419153	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	1.8810376442461656	[46,35]	[0,0]	7	hSpCas9	positive selection	3353276
6419044	6419067	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	4.449971289388231	[6,6]	[0,0]	9	hSpCas9	positive selection	3353277
6419314	6419337	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.4500329206350477	[208,208]	[0,0]	-3	hSpCas9	positive selection	3372469
6419233	6419256	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.43616074605349014	[206,206]	[0,0]	-3	hSpCas9	positive selection	3372470
6419630	6419653	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.4908666381436253	[214,214]	[0,0]	-3	hSpCas9	positive selection	3372471
6419313	6419336	1	-	26780180	HT29	viability (Avana library 4 designs)	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	1.4044625269372	[]	[]	5	hSpCas9	negative selection	3430351
6419272	6419295	1	+	26780180	HT29	viability (Avana library 4 designs)	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	-0.213866309303834	[]	[]	-3	hSpCas9	negative selection	3430352
6419250	6419273	1	-	26780180	HT29	viability (Avana library 4 designs)	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	1.00610819970556	[]	[]	4	hSpCas9	negative selection	3430353
6419787	6419810	1	-	26780180	HT29	viability (Avana library 4 designs)	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	2.25913932335376	[]	[]	7	hSpCas9	negative selection	3430354
6419272	6419295	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	3.74174151201925	[]	[]	6	hSpCas9	negative selection	3515469
6419250	6419273	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	3.1279193988356	[]	[]	5	hSpCas9	negative selection	3515470
6419313	6419336	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-1.69116127004662	[]	[]	-2	hSpCas9	negative selection	3515471
6419787	6419810	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	2.35470502277059	[]	[]	3	hSpCas9	negative selection	3515472
6419602	6419625	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	1.50202590684741	[]	[]	2	hSpCas9	negative selection	3515473
6419654	6419677	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	2.72388433231258	[]	[]	4	hSpCas9	negative selection	3515474
6419272	6419295	1	+	26780180	A375	viability (Avana lentiGuide)	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	-1.81499683775954	[]	[]	-3	hSpCas9	negative selection	3624128
6419250	6419273	1	-	26780180	A375	viability (Avana lentiGuide)	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	4.2266635421624	[]	[]	4	hSpCas9	negative selection	3624129
6419313	6419336	1	-	26780180	A375	viability (Avana lentiGuide)	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	3.67745167335805	[]	[]	3	hSpCas9	negative selection	3624130
6419787	6419810	1	-	26780180	A375	viability (Avana lentiGuide)	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	15.1545695612371	[]	[]	8	hSpCas9	negative selection	3624131
6419602	6419625	1	+	26780180	A375	viability (Avana lentiGuide)	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	6.37646031606959	[]	[]	5	hSpCas9	negative selection	3624132
6419654	6419677	1	+	26780180	A375	viability (Avana lentiGuide)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.29347550214342	[]	[]	1	hSpCas9	negative selection	3624133
6419272	6419295	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	0.2275187566002522	[4]	[5,4]	6	hSpCas9	positive selection	3732787
6419250	6419273	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	0.05194329534873913	[4]	[5,4]	1	hSpCas9	positive selection	3732788
6419313	6419336	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.6980299136749889	[4]	[3,1]	-7	hSpCas9	positive selection	3732789
6419787	6419810	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	-0.2819309549446645	[4]	[3,2]	-4	hSpCas9	positive selection	3732790
6419602	6419625	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.15895036195690074	[4]	[4,2]	-3	hSpCas9	positive selection	3732791
6419654	6419677	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.1582431799298347	[5]	[6,6]	4	hSpCas9	positive selection	3732792
6419272	6419295	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCTCCTGCAGGAAGCGCACGG	HES2	ENSG00000069812	-0.020955882050592844	[5]	[4,4]	0	hSpCas9	positive selection	3841394
6419250	6419273	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGCGTCCTCATGGCCCACGG	HES2	ENSG00000069812	-0.4166049657668952	[5]	[5,1]	-5	hSpCas9	positive selection	3841395
6419313	6419336	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-1.2058056862870672	[4]	[1,0]	-9	hSpCas9	positive selection	3841396
6419787	6419810	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGCCGGGCAGGGGACGCGGCGG	HES2	ENSG00000069812	-0.7639673192587252	[4]	[1,1]	-7	hSpCas9	positive selection	3841397
6419602	6419625	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.8802257282422122	[4]	[1,1]	-8	hSpCas9	positive selection	3841398
6419654	6419677	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.04863781996932831	[6]	[5,5]	1	hSpCas9	positive selection	3841399
6419044	6419067	1	+	26780180	A375	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.591189641327706	[]	[]	1	hSpCas9	negative selection	3947461
6419314	6419337	1	+	26780180	A375	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.370726058053513	[]	[]	0	hSpCas9	negative selection	3947462
6419130	6419153	1	-	26780180	A375	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.862357274541251	[]	[]	3	hSpCas9	negative selection	3947463
6419233	6419256	1	+	26780180	A375	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	1.75060966497455	[]	[]	9	hSpCas9	negative selection	3947464
6419654	6419677	1	+	26780180	A375	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.793925454597384	[]	[]	3	hSpCas9	negative selection	3947465
6419630	6419653	1	+	26780180	A375	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.72672377464733	[]	[]	2	hSpCas9	negative selection	3947466
6419044	6419067	1	+	26780180	HT29	viability (GeCKOv2 library)	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.920907814271842	[]	[]	4	hSpCas9	negative selection	4055427
6419314	6419337	1	+	26780180	HT29	viability (GeCKOv2 library)	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.459770378339482	[]	[]	1	hSpCas9	negative selection	4055428
6419130	6419153	1	-	26780180	HT29	viability (GeCKOv2 library)	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.653879747514171	[]	[]	2	hSpCas9	negative selection	4055429
6419233	6419256	1	+	26780180	HT29	viability (GeCKOv2 library)	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	1.58029058989438	[]	[]	8	hSpCas9	negative selection	4055430
6419654	6419677	1	+	26780180	HT29	viability (GeCKOv2 library)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.37854961927482	[]	[]	7	hSpCas9	negative selection	4055431
6419630	6419653	1	+	26780180	HT29	viability (GeCKOv2 library)	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.98678152825091	[]	[]	4	hSpCas9	negative selection	4055432
6419314	6419337	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.00535682977723851	[3]	[2,1]	0	hSpCas9	positive selection	4142301
6419233	6419256	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.13102543150972373	[3]	[2,3]	3	hSpCas9	positive selection	4142302
6419654	6419677	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.06269100437788541	[3]	[1,1]	-1	hSpCas9	positive selection	4142303
6419314	6419337	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.16744267032919966	[4]	[3,0,4,0]	1	hSpCas9	positive selection	4206323
6419233	6419256	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.1909328069182953	[4]	[3,4,1,0]	1	hSpCas9	positive selection	4206324
6419654	6419677	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.3868806115818626	[3]	[3,2,4,0]	3	hSpCas9	positive selection	4206325
6419654	6419677	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.10266323208979788	[1]	[1,0]	-2	hSpCas9	positive selection	4274859
6419130	6419153	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.23527882795041	[1]	[1,0]	-5	hSpCas9	positive selection	4274860
6419044	6419067	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.18917464190520006	[0]	[0,0]	-4	hSpCas9	positive selection	4274861
6419314	6419337	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.3274411659551078	[2]	[3,2]	6	hSpCas9	positive selection	4339120
6419233	6419256	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.31737308463637537	[3]	[3,0]	-6	hSpCas9	positive selection	4339121
6419630	6419653	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.0361664664376041	[3]	[3,1]	0	hSpCas9	positive selection	4339122
6419139	6419161	1	+	27760321	OCIAML3	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	0.83493965523605	[642,561]	[618,1124]	8	hSpCas9	negative selection	4406683
6419235	6419257	1	+	27760321	OCIAML3	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.35367022419299454	[1090,949]	[917,1146]	4	hSpCas9	negative selection	4406684
6419301	6419323	1	-	27760321	OCIAML3	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.2574184435843655	[371,316]	[241,423]	3	hSpCas9	negative selection	4406685
6419315	6419337	1	+	27760321	OCIAML3	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.8165902294880909	[723,729]	[856,1197]	8	hSpCas9	negative selection	4406686
6419625	6419647	1	+	27760321	OCIAML3	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-0.1072471857751659	[409,329]	[244,295]	-1	hSpCas9	negative selection	4406687
6419139	6419161	1	+	27760321	OCIAML2	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.04779365285778048	[642,561]	[381,586]	0	hSpCas9	negative selection	4490146
6419235	6419257	1	+	27760321	OCIAML2	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.4707445293619916	[1090,949]	[988,1341]	6	hSpCas9	negative selection	4490147
6419301	6419323	1	-	27760321	OCIAML2	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.6718123568599297	[371,316]	[366,541]	8	hSpCas9	negative selection	4490148
6419315	6419337	1	+	27760321	OCIAML2	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.38136994933158364	[723,729]	[666,902]	5	hSpCas9	negative selection	4490149
6419625	6419647	1	+	27760321	OCIAML2	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	0.2638661907560702	[409,329]	[343,374]	3	hSpCas9	negative selection	4490150
6419139	6419161	1	+	27760321	MV411	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	0.38394402492468566	[642,561]	[587,411]	2	hSpCas9	negative selection	4573609
6419235	6419257	1	+	27760321	MV411	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.949725604952222	[1090,949]	[1570,886]	7	hSpCas9	negative selection	4573610
6419301	6419323	1	-	27760321	MV411	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	-1.2940647845473725	[371,316]	[97,83]	-7	hSpCas9	negative selection	4573611
6419315	6419337	1	+	27760321	MV411	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	1.0572976282157498	[723,729]	[744,1387]	7	hSpCas9	negative selection	4573612
6419625	6419647	1	+	27760321	MV411	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-1.3328575357519648	[409,329]	[79,120]	-7	hSpCas9	negative selection	4573613
6419139	6419161	1	+	27760321	HL60	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	0.38097543019831387	[642,561]	[555,727]	5	hSpCas9	negative selection	4657072
6419235	6419257	1	+	27760321	HL60	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.1319864327383884	[1090,949]	[1053,759]	1	hSpCas9	negative selection	4657073
6419301	6419323	1	-	27760321	HL60	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.40982718932744894	[371,316]	[393,349]	5	hSpCas9	negative selection	4657074
6419315	6419337	1	+	27760321	HL60	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.6448363781487556	[723,729]	[1011,846]	7	hSpCas9	negative selection	4657075
6419625	6419647	1	+	27760321	HL60	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	0.00018767455672652478	[409,329]	[253,349]	0	hSpCas9	negative selection	4657076
6419139	6419161	1	+	27760321	HT1080	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	0.45426468138612625	[561,438]	[371,164]	2	hSpCas9	negative selection	4740535
6419235	6419257	1	+	27760321	HT1080	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	1.2728431548823442	[949,741]	[959,654]	7	hSpCas9	negative selection	4740536
6419301	6419323	1	-	27760321	HT1080	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	-0.5734715469161804	[316,247]	[67,83]	-3	hSpCas9	negative selection	4740537
6419315	6419337	1	+	27760321	HT1080	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	1.0816956830964657	[729,569]	[538,557]	6	hSpCas9	negative selection	4740538
6419625	6419647	1	+	27760321	HT1080	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	0.5232963195499667	[329,257]	[122,217]	2	hSpCas9	negative selection	4740539
6419139	6419161	1	+	27760321	HT29	viability after 7 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.4006171602145342	[561,438]	[530,417,517]	-5	hSpCas9	negative selection	4823998
6419235	6419257	1	+	27760321	HT29	viability after 7 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.5584442354255059	[949,741]	[1696,1612,1509]	8	hSpCas9	negative selection	4823999
6419301	6419323	1	-	27760321	HT29	viability after 7 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.5448074888593408	[316,247]	[589,425,579]	8	hSpCas9	negative selection	4824000
6419315	6419337	1	+	27760321	HT29	viability after 7 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.2330683136215731	[729,569]	[879,747,533]	-3	hSpCas9	negative selection	4824001
6419625	6419647	1	+	27760321	HT29	viability after 7 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-0.5986778501546893	[329,257]	[419,234,121]	-7	hSpCas9	negative selection	4824002
6419139	6419161	1	+	27760321	HT29	viability after 25 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.22696122080819714	[561,438]	[471,501,492]	-2	hSpCas9	negative selection	4907461
6419235	6419257	1	+	27760321	HT29	viability after 25 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.4208471516669181	[949,741]	[1304,1086,1510]	4	hSpCas9	negative selection	4907462
6419301	6419323	1	-	27760321	HT29	viability after 25 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.22157988312069646	[316,247]	[285,399,456]	2	hSpCas9	negative selection	4907463
6419315	6419337	1	+	27760321	HT29	viability after 25 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.1469306326994959	[729,569]	[1010,649,789]	1	hSpCas9	negative selection	4907464
6419625	6419647	1	+	27760321	HT29	viability after 25 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-0.7500855710449161	[329,257]	[153,264,180]	-6	hSpCas9	negative selection	4907465
6419139	6419161	1	+	27760321	HT29	viability after 22 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.6408287151992513	[561,438]	[206,406,504]	-5	hSpCas9	negative selection	4990924
6419235	6419257	1	+	27760321	HT29	viability after 22 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.45503998481344965	[949,741]	[1376,1325,1317]	5	hSpCas9	negative selection	4990925
6419301	6419323	1	-	27760321	HT29	viability after 22 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.4988006218153465	[316,247]	[492,508,380]	5	hSpCas9	negative selection	4990926
6419315	6419337	1	+	27760321	HT29	viability after 22 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.019172521806415377	[729,569]	[551,903,773]	0	hSpCas9	negative selection	4990927
6419625	6419647	1	+	27760321	HT29	viability after 22 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-0.15586722204563025	[329,257]	[158,376,383]	-1	hSpCas9	negative selection	4990928
6419139	6419161	1	+	27760321	HT29	viability after 19 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.13483789123857987	[561,438]	[497,292,760]	-1	hSpCas9	negative selection	5074387
6419235	6419257	1	+	27760321	HT29	viability after 19 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.370145416395151	[949,741]	[1717,1048,1040]	3	hSpCas9	negative selection	5074388
6419301	6419323	1	-	27760321	HT29	viability after 19 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.7184028975020904	[316,247]	[379,511,680]	7	hSpCas9	negative selection	5074389
6419315	6419337	1	+	27760321	HT29	viability after 19 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.014332135619433362	[729,569]	[646,483,1054]	0	hSpCas9	negative selection	5074390
6419625	6419647	1	+	27760321	HT29	viability after 19 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-1.208444063993156	[329,257]	[119,173,139]	-7	hSpCas9	negative selection	5074391
6419139	6419161	1	+	27760321	HT29	viability after 16 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.26758899118255985	[561,438]	[302,509,565]	-3	hSpCas9	negative selection	5157850
6419235	6419257	1	+	27760321	HT29	viability after 16 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.3367662490499086	[949,741]	[1481,1047,1086]	4	hSpCas9	negative selection	5157851
6419301	6419323	1	-	27760321	HT29	viability after 16 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	-0.16986159875137485	[316,247]	[281,320,238]	-2	hSpCas9	negative selection	5157852
6419315	6419337	1	+	27760321	HT29	viability after 16 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.21492771606965944	[729,569]	[851,279,777]	-2	hSpCas9	negative selection	5157853
6419625	6419647	1	+	27760321	HT29	viability after 16 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	0.1465851155609003	[329,257]	[320,413,351]	1	hSpCas9	negative selection	5157854
6419139	6419161	1	+	27760321	HT29	viability after 13 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.48175530365268904	[561,438]	[234,412,588]	-5	hSpCas9	negative selection	5241313
6419235	6419257	1	+	27760321	HT29	viability after 13 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.537747920174992	[949,741]	[1598,1388,1293]	7	hSpCas9	negative selection	5241314
6419301	6419323	1	-	27760321	HT29	viability after 13 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.31607299008307554	[316,247]	[336,286,588]	4	hSpCas9	negative selection	5241315
6419315	6419337	1	+	27760321	HT29	viability after 13 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.268428716185677	[729,569]	[609,554,707]	-3	hSpCas9	negative selection	5241316
6419625	6419647	1	+	27760321	HT29	viability after 13 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-0.14802897838501616	[329,257]	[298,205,411]	-2	hSpCas9	negative selection	5241317
6419139	6419161	1	+	27760321	HT29	viability after 10 days	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	-0.3929059880855421	[561,438]	[571,557,303]	-5	hSpCas9	negative selection	5324776
6419235	6419257	1	+	27760321	HT29	viability after 10 days	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.2650555852368661	[949,741]	[1189,1346,1272]	3	hSpCas9	negative selection	5324777
6419301	6419323	1	-	27760321	HT29	viability after 10 days	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.025464572966479637	[316,247]	[446,397,235]	0	hSpCas9	negative selection	5324778
6419315	6419337	1	+	27760321	HT29	viability after 10 days	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.28508980082444346	[729,569]	[568,647,777]	-4	hSpCas9	negative selection	5324779
6419625	6419647	1	+	27760321	HT29	viability after 10 days	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	0.3546235296856892	[329,257]	[337,504,563]	5	hSpCas9	negative selection	5324780
6419139	6419161	1	+	27760321	MOLM13	viability	AGCTGTCGCAAGGCACTGCGGG	HES2	ENSG00000069812	0.16947094197880103	[642,561]	[704,105]	1	hSpCas9	negative selection	5408239
6419235	6419257	1	+	27760321	MOLM13	viability	ACTCACGGGGCGCTGCCGTGGG	HES2	ENSG00000069812	0.9061340382364156	[1090,949]	[1312,874]	6	hSpCas9	negative selection	5408240
6419301	6419323	1	-	27760321	MOLM13	viability	CTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	-0.49750294377915705	[371,316]	[187,93]	-3	hSpCas9	negative selection	5408241
6419315	6419337	1	+	27760321	MOLM13	viability	TTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	1.0069160924794922	[723,729]	[937,732]	7	hSpCas9	negative selection	5408242
6419625	6419647	1	+	27760321	MOLM13	viability	CAGGATGAGCCCCTTAAGCTGG	HES2	ENSG00000069812	-1.7224413705227308	[409,329]	[43,78]	-7	hSpCas9	negative selection	5408243
6419500	6419523	1	+	27661255	K562	viability	GGGCGCCGCGCGGAACCCCCTGG	HES2	ENSG00000069812	0.15419917165495783	[934,1013]	[905,829]	5	dCas9-KRAB	negative selection	5484477
6419504	6419527	1	+	27661255	K562	viability	GCCGCGCGGAACCCCCTGGTGGG	HES2	ENSG00000069812	0.2618123961812091	[95,193]	[154,121]	8	dCas9-KRAB	negative selection	5484478
6419870	6419893	1	+	27661255	K562	viability	GAGGTCCGAAATGAGGTCCCGGG	HES2	ENSG00000069812	0.2435625736530759	[539,585]	[576,492]	7	dCas9-KRAB	negative selection	5484479
6424242	6424265	1	+	27661255	K562	viability	GGGCAGTTCTCGGATCTGGAGGG	HES2	ENSG00000069812	0.18942579387076597	[1292,1275]	[1260,1092]	6	dCas9-KRAB	negative selection	5484480
6424592	6424615	1	+	27661255	K562	viability	GGGGTCTCAACTGTTACGTGAGG	HES2	ENSG00000069812	0.29297447019653483	[963,1135]	[1131,932]	8	dCas9-KRAB	negative selection	5484481
6424654	6424677	1	+	27661255	K562	viability	GCACGAGTGTCCCCGCGTCGCGG	HES2	ENSG00000069812	0.08206691269890959	[549,606]	[470,502]	3	dCas9-KRAB	negative selection	5484482
6419493	6419516	1	-	27661255	K562	viability	GTTCCGCGCGGCGCCCGAGGCGG	HES2	ENSG00000069812	-0.5485175244568398	[773,910]	[508,415]	-8	dCas9-KRAB	negative selection	5484483
6419910	6419933	1	-	27661255	K562	viability	GGGCGGGGCGCGCACTCGTCTGG	HES2	ENSG00000069812	0.25758194625860076	[613,521]	[577,514]	8	dCas9-KRAB	negative selection	5484484
6424294	6424317	1	-	27661255	K562	viability	GGGCTCTGGGTCGAAATCCCCGG	HES2	ENSG00000069812	0.03224492695918324	[585,764]	[607,498]	1	dCas9-KRAB	negative selection	5484485
6419654	6419677	1	+	27260156	BXPC3	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.21890491009912738	[153]	[117,118,119,206]	-5	hSpCas9	negative selection	5547319
6419130	6419153	1	-	27260156	BXPC3	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.04378696546953842	[136]	[120,126,187,159]	1	hSpCas9	negative selection	5547320
6419044	6419067	1	+	27260156	BXPC3	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.29719000715068766	[45]	[35,30,53,35]	-6	hSpCas9	negative selection	5547321
6419314	6419337	1	+	27260156	BXPC3	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.09674337490050008	[451]	[498,465,499,562]	2	hSpCas9	negative selection	5611580
6419233	6419256	1	+	27260156	BXPC3	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.14161586271530696	[570]	[550,687,481,951]	3	hSpCas9	negative selection	5611581
6419630	6419653	1	+	27260156	BXPC3	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.16451472504586107	[656]	[594,512,640,719]	-4	hSpCas9	negative selection	5611582
6419654	6419677	1	+	27260156	A673	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.21307578579593067	[153]	[310,131,172,256]	5	hSpCas9	negative selection	5668570
6419130	6419153	1	-	27260156	A673	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.19583363658283814	[136]	[141,204,142,261]	4	hSpCas9	negative selection	5668571
6419044	6419067	1	+	27260156	A673	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.24764073994905855	[45]	[58,41,48,36]	-6	hSpCas9	negative selection	5668572
6419314	6419337	1	+	27260156	A673	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.36665603026301324	[451]	[705,584,771,739]	8	hSpCas9	negative selection	5732831
6419233	6419256	1	+	27260156	A673	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.09787440068422681	[570]	[864,737,665,676]	2	hSpCas9	negative selection	5732832
6419630	6419653	1	+	27260156	A673	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.021862038111185256	[656]	[802,730,835,737]	0	hSpCas9	negative selection	5732833
6419654	6419677	1	+	27260156	A375	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.022782397394617515	[153]	[115,170,276,145]	0	hSpCas9	negative selection	5789821
6419130	6419153	1	-	27260156	A375	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.15652735416475294	[136]	[247,277,58,145]	2	hSpCas9	negative selection	5789822
6419044	6419067	1	+	27260156	A375	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-1.5344038465668288	[45]	[15,22,28,7]	-9	hSpCas9	negative selection	5789823
6419314	6419337	1	+	27260156	A375	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.6461436436108274	[451]	[715,1236,782,643]	8	hSpCas9	negative selection	5854082
6419233	6419256	1	+	27260156	A375	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.40695787467416805	[570]	[871,1163,823,730]	6	hSpCas9	negative selection	5854083
6419630	6419653	1	+	27260156	A375	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.09525848957213628	[656]	[619,994,793,522]	-1	hSpCas9	negative selection	5854084
6419654	6419677	1	+	27260156	COLO741	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.522241074925567	[153]	[132,148,128]	-8	hSpCas9	negative selection	5911072
6419130	6419153	1	-	27260156	COLO741	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.8035068762188933	[136]	[104,122,74]	-9	hSpCas9	negative selection	5911073
6419044	6419067	1	+	27260156	COLO741	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-1.1138845172917473	[45]	[22,29,27]	-9	hSpCas9	negative selection	5911074
6419314	6419337	1	+	27260156	COLO741	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.13863468655017125	[451]	[659,724,530]	3	hSpCas9	negative selection	5975333
6419233	6419256	1	+	27260156	COLO741	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.27641419646519255	[570]	[1051,756,855]	6	hSpCas9	negative selection	5975334
6419630	6419653	1	+	27260156	COLO741	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.07944413738837353	[656]	[937,625,826]	-2	hSpCas9	negative selection	5975335
6419654	6419677	1	+	27260156	CAL120	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.6671659586991037	[153]	[171,92,104]	-7	hSpCas9	negative selection	6032323
6419130	6419153	1	-	27260156	CAL120	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.31816945842021327	[136]	[82,121,195]	-5	hSpCas9	negative selection	6032324
6419044	6419067	1	+	27260156	CAL120	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.7097882217917317	[45]	[67,9,31]	-7	hSpCas9	negative selection	6032325
6419314	6419337	1	+	27260156	CAL120	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.2958444803614203	[451]	[710,714,648]	4	hSpCas9	negative selection	6096584
6419233	6419256	1	+	27260156	CAL120	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.10590127091201001	[570]	[1121,547,678]	1	hSpCas9	negative selection	6096585
6419630	6419653	1	+	27260156	CAL120	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.1836295375533124	[656]	[616,371,1146]	-3	hSpCas9	negative selection	6096586
6419654	6419677	1	+	27260156	CADOES1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.35936979908450084	[153]	[124,237,168,203]	6	hSpCas9	negative selection	6153574
6419130	6419153	1	-	27260156	CADOES1	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.13407521929422095	[136]	[157,87,227,82]	2	hSpCas9	negative selection	6153575
6419044	6419067	1	+	27260156	CADOES1	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.7558137163946284	[45]	[30,8,17,43]	-8	hSpCas9	negative selection	6153576
6419314	6419337	1	+	27260156	CADOES1	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.6377880906904336	[451]	[469,1014,443,689]	9	hSpCas9	negative selection	6217835
6419233	6419256	1	+	27260156	CADOES1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.23997660295927886	[570]	[443,779,720,561]	4	hSpCas9	negative selection	6217836
6419630	6419653	1	+	27260156	CADOES1	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.20213955062080025	[656]	[480,549,582,509]	-4	hSpCas9	negative selection	6217837
6419654	6419677	1	+	27260156	EWS502	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.6640744928628151	[153]	[98,132,94,81]	-8	hSpCas9	negative selection	6274825
6419130	6419153	1	-	27260156	EWS502	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.18063291484510757	[136]	[120,182,243,110]	3	hSpCas9	negative selection	6274826
6419044	6419067	1	+	27260156	EWS502	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.9217908099244725	[45]	[9,28,51,12]	-8	hSpCas9	negative selection	6274827
6419314	6419337	1	+	27260156	EWS502	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.30753286693297077	[451]	[786,501,431,626]	5	hSpCas9	negative selection	6339086
6419233	6419256	1	+	27260156	EWS502	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.45979053660973096	[570]	[789,928,696,912]	7	hSpCas9	negative selection	6339087
6419630	6419653	1	+	27260156	EWS502	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.07308940871515057	[656]	[606,561,751,739]	-1	hSpCas9	negative selection	6339088
6419654	6419677	1	+	27260156	EW8	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.14681371250927056	[153]	[146,59,130,112]	-3	hSpCas9	negative selection	6396076
6419130	6419153	1	-	27260156	EW8	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.47280736778668997	[136]	[151,175,116,176]	8	hSpCas9	negative selection	6396077
6419044	6419067	1	+	27260156	EW8	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.6514236583303767	[45]	[5,3,51,25]	-8	hSpCas9	negative selection	6396078
6419314	6419337	1	+	27260156	EW8	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.5321999431726954	[451]	[555,405,573,575]	8	hSpCas9	negative selection	6460337
6419233	6419256	1	+	27260156	EW8	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.30687046724514494	[570]	[622,681,425,587]	5	hSpCas9	negative selection	6460338
6419630	6419653	1	+	27260156	EW8	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.05221297194001556	[656]	[637,507,390,549]	-1	hSpCas9	negative selection	6460339
6419654	6419677	1	+	27260156	CORL105	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.2522547037838825	[153]	[152,242,351,129]	5	hSpCas9	negative selection	6517327
6419130	6419153	1	-	27260156	CORL105	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.4478770141878512	[136]	[297,153,255,176]	7	hSpCas9	negative selection	6517328
6419044	6419067	1	+	27260156	CORL105	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.27455744229673185	[45]	[30,59,56,109]	5	hSpCas9	negative selection	6517329
6419314	6419337	1	+	27260156	CORL105	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.3011465922868475	[451]	[653,534,935,529]	5	hSpCas9	negative selection	6581588
6419233	6419256	1	+	27260156	CORL105	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.2596941980382294	[570]	[817,787,857,746]	5	hSpCas9	negative selection	6581589
6419630	6419653	1	+	27260156	CORL105	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.058815175398349184	[656]	[707,716,759,770]	-1	hSpCas9	negative selection	6581590
6419654	6419677	1	+	27260156	HS294T	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.2959491387886377	[153]	[49,74,47,130]	4	hSpCas9	negative selection	6638578
6419130	6419153	1	-	27260156	HS294T	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.03911393460774337	[136]	[65,29,62,58]	0	hSpCas9	negative selection	6638579
6419044	6419067	1	+	27260156	HS294T	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.7448675769179522	[45]	[12,12,10,3]	-8	hSpCas9	negative selection	6638580
6419314	6419337	1	+	27260156	HS294T	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.3122426463120793	[451]	[168,132,339,235]	4	hSpCas9	negative selection	6702839
6419233	6419256	1	+	27260156	HS294T	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.4190603249143567	[570]	[266,294,347,267]	5	hSpCas9	negative selection	6702840
6419630	6419653	1	+	27260156	HS294T	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.162631070598307	[656]	[201,201,235,278]	-2	hSpCas9	negative selection	6702841
6419654	6419677	1	+	27260156	HCC44	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.5609637033875174	[153]	[110,100,186,86]	-7	hSpCas9	negative selection	6759829
6419130	6419153	1	-	27260156	HCC44	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.17880038841645396	[136]	[106,159,154,121]	-3	hSpCas9	negative selection	6759830
6419044	6419067	1	+	27260156	HCC44	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.04605885011938593	[45]	[38,71,82,9]	0	hSpCas9	negative selection	6759831
6419314	6419337	1	+	27260156	HCC44	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.16698349196150575	[451]	[373,713,572,590]	2	hSpCas9	negative selection	6824090
6419233	6419256	1	+	27260156	HCC44	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.26169023112223816	[570]	[748,583,699,1059]	4	hSpCas9	negative selection	6824091
6419630	6419653	1	+	27260156	HCC44	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.16881351659630583	[656]	[632,689,799,536]	-3	hSpCas9	negative selection	6824092
6419654	6419677	1	+	27260156	G402	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.19004039799531136	[153]	[139,300,107,115]	-2	hSpCas9	negative selection	6881080
6419130	6419153	1	-	27260156	G402	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.14139151443383757	[136]	[172,340,43,65]	-2	hSpCas9	negative selection	6881081
6419044	6419067	1	+	27260156	G402	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.0430231080760235	[45]	[36,124,17,39]	0	hSpCas9	negative selection	6881082
6419314	6419337	1	+	27260156	G402	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.5242919922277088	[451]	[974,1115,757,385]	6	hSpCas9	negative selection	6945341
6419233	6419256	1	+	27260156	G402	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.4596438026231318	[570]	[1307,737,891,929]	6	hSpCas9	negative selection	6945342
6419630	6419653	1	+	27260156	G402	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.07050989865988222	[656]	[821,920,786,548]	-1	hSpCas9	negative selection	6945343
6419654	6419677	1	+	27260156	L33	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.237184691132581	[153]	[136,72,108,237]	5	hSpCas9	negative selection	7002331
6419130	6419153	1	-	27260156	L33	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.9095789313314692	[136]	[217,124,192,200]	9	hSpCas9	negative selection	7002332
6419044	6419067	1	+	27260156	L33	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.04389733893829417	[45]	[42,10,36,60]	1	hSpCas9	negative selection	7002333
6419314	6419337	1	+	27260156	L33	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.1495630318115906	[451]	[439,202,317,564]	3	hSpCas9	negative selection	7066592
6419233	6419256	1	+	27260156	L33	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.3321702188925381	[570]	[611,255,525,803]	7	hSpCas9	negative selection	7066593
6419630	6419653	1	+	27260156	L33	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.283451156936804	[656]	[565,226,251,635]	-6	hSpCas9	negative selection	7066594
6419654	6419677	1	+	27260156	K562	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.4958441637235327	[153]	[207,123,55,18]	-5	hSpCas9	negative selection	7123582
6419130	6419153	1	-	27260156	K562	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.2424833120844141	[136]	[141,186,49,45]	-3	hSpCas9	negative selection	7123583
6419044	6419067	1	+	27260156	K562	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.7739446903935048	[45]	[0,2,69,18]	-7	hSpCas9	negative selection	7123584
6419314	6419337	1	+	27260156	K562	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	-0.0033824215322838386	[451]	[675,446,241,273]	0	hSpCas9	negative selection	7187843
6419233	6419256	1	+	27260156	K562	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.36868589824566717	[570]	[545,652,597,791]	4	hSpCas9	negative selection	7187844
6419630	6419653	1	+	27260156	K562	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.38417350362803077	[656]	[521,269,477,504]	-5	hSpCas9	negative selection	7187845
6419654	6419677	1	+	27260156	HT29	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.05061351894905686	[153]	[286,125,156,157]	-1	hSpCas9	negative selection	7244833
6419130	6419153	1	-	27260156	HT29	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.5123636757145067	[136]	[211,358,193,196]	8	hSpCas9	negative selection	7244834
6419044	6419067	1	+	27260156	HT29	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.25014996205712814	[45]	[93,42,33,22]	-5	hSpCas9	negative selection	7244835
6419314	6419337	1	+	27260156	HT29	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.232019670424789	[451]	[753,550,618,651]	4	hSpCas9	negative selection	7309094
6419233	6419256	1	+	27260156	HT29	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.1400407214062791	[570]	[774,830,811,655]	2	hSpCas9	negative selection	7309095
6419630	6419653	1	+	27260156	HT29	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.10399727861627461	[656]	[951,1033,735,741]	2	hSpCas9	negative selection	7309096
6419654	6419677	1	+	27260156	MHHES1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.22716084740039855	[153]	[153,211,331,123]	4	hSpCas9	negative selection	7366084
6419130	6419153	1	-	27260156	MHHES1	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.08114819862708922	[136]	[209,168,127,150]	1	hSpCas9	negative selection	7366085
6419044	6419067	1	+	27260156	MHHES1	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.041274668864811126	[45]	[79,54,68,9]	0	hSpCas9	negative selection	7366086
6419314	6419337	1	+	27260156	MHHES1	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.35782112122153326	[451]	[759,517,664,650]	6	hSpCas9	negative selection	7430345
6419233	6419256	1	+	27260156	MHHES1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.22800344458235272	[570]	[850,936,710,569]	4	hSpCas9	negative selection	7430346
6419630	6419653	1	+	27260156	MHHES1	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.007060572011168442	[656]	[679,761,733,768]	0	hSpCas9	negative selection	7430347
6419654	6419677	1	+	27260156	MEWO	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.2320640548489019	[153]	[142,105,122]	-5	hSpCas9	negative selection	7487335
6419130	6419153	1	-	27260156	MEWO	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.36696292855474444	[136]	[77,97,117]	-7	hSpCas9	negative selection	7487336
6419044	6419067	1	+	27260156	MEWO	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.5087893628019708	[45]	[20,17,49]	-8	hSpCas9	negative selection	7487337
6419314	6419337	1	+	27260156	MEWO	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.04400363601350596	[451]	[605,385,348]	1	hSpCas9	negative selection	7551596
6419233	6419256	1	+	27260156	MEWO	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.014588526541166214	[570]	[571,550,501]	0	hSpCas9	negative selection	7551597
6419630	6419653	1	+	27260156	MEWO	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.025853027922443705	[656]	[687,676,523]	0	hSpCas9	negative selection	7551598
6419654	6419677	1	+	27260156	LNCAPCLONEFGC	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.42380438157515443	[153]	[74,134,80,119]	-6	hSpCas9	negative selection	7608586
6419130	6419153	1	-	27260156	LNCAPCLONEFGC	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.07332438673692399	[136]	[125,134,87,116]	-1	hSpCas9	negative selection	7608587
6419044	6419067	1	+	27260156	LNCAPCLONEFGC	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.34445628086515123	[45]	[27,5,31,66]	-5	hSpCas9	negative selection	7608588
6419314	6419337	1	+	27260156	LNCAPCLONEFGC	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.23235322894232885	[451]	[436,480,490,516]	3	hSpCas9	negative selection	7672847
6419233	6419256	1	+	27260156	LNCAPCLONEFGC	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.36926500175577254	[570]	[691,648,702,633]	6	hSpCas9	negative selection	7672848
6419630	6419653	1	+	27260156	LNCAPCLONEFGC	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.12261280777947037	[656]	[477,510,728,498]	-2	hSpCas9	negative selection	7672849
6419654	6419677	1	+	27260156	PANC0327	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.8502290846886117	[153]	[59,68,759,105]	9	hSpCas9	negative selection	7729837
6419130	6419153	1	-	27260156	PANC0327	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.03876582431047648	[136]	[147,177,77,90]	0	hSpCas9	negative selection	7729838
6419044	6419067	1	+	27260156	PANC0327	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-2.4967438587849533	[45]	[2,11,8,3]	-9	hSpCas9	negative selection	7729839
6419314	6419337	1	+	27260156	PANC0327	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.10470810052877488	[451]	[603,398,320,420]	1	hSpCas9	negative selection	7794098
6419233	6419256	1	+	27260156	PANC0327	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.537637299694314	[570]	[844,702,1090,319]	7	hSpCas9	negative selection	7794099
6419630	6419653	1	+	27260156	PANC0327	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.47578593471460207	[656]	[407,515,331,408]	-6	hSpCas9	negative selection	7794100
6419654	6419677	1	+	27260156	NCIH2009	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.2393294073568244	[153]	[244,121,192]	-3	hSpCas9	negative selection	7851088
6419130	6419153	1	-	27260156	NCIH2009	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.5501218240940327	[136]	[364,283,207]	7	hSpCas9	negative selection	7851089
6419044	6419067	1	+	27260156	NCIH2009	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.3586773546950166	[45]	[102,35,112]	5	hSpCas9	negative selection	7851090
6419314	6419337	1	+	27260156	NCIH2009	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.3940699002149152	[451]	[834,951,699]	5	hSpCas9	negative selection	7915349
6419233	6419256	1	+	27260156	NCIH2009	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.4182837259325774	[570]	[1119,632,1461]	6	hSpCas9	negative selection	7915350
6419630	6419653	1	+	27260156	NCIH2009	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.13555191553000412	[656]	[1037,858,647]	-2	hSpCas9	negative selection	7915351
6419654	6419677	1	+	27260156	NCIH1373	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.9822548171325096	[153]	[96,77,95,20]	-7	hSpCas9	negative selection	7972339
6419130	6419153	1	-	27260156	NCIH1373	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.11087845029318255	[136]	[113,108,162,73]	1	hSpCas9	negative selection	7972340
6419044	6419067	1	+	27260156	NCIH1373	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.9191846899387106	[45]	[3,11,24,17]	-7	hSpCas9	negative selection	7972341
6419314	6419337	1	+	27260156	NCIH1373	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.433188782170943	[451]	[755,488,915,155]	4	hSpCas9	negative selection	8036600
6419233	6419256	1	+	27260156	NCIH1373	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.22245932201185065	[570]	[741,637,574,278]	2	hSpCas9	negative selection	8036601
6419630	6419653	1	+	27260156	NCIH1373	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.15325389718812998	[656]	[684,1124,834,145]	1	hSpCas9	negative selection	8036602
6419654	6419677	1	+	27260156	PATU8902	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.4713197202762047	[153]	[445,68,353,300]	5	hSpCas9	negative selection	8093590
6419130	6419153	1	-	27260156	PATU8902	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.022829066494390426	[136]	[55,563,114,15]	0	hSpCas9	negative selection	8093591
6419044	6419067	1	+	27260156	PATU8902	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.4958316129872786	[45]	[55,250,44,11]	5	hSpCas9	negative selection	8093592
6419314	6419337	1	+	27260156	PATU8902	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.664653716592825	[451]	[1389,772,679,1246]	7	hSpCas9	negative selection	8157851
6419233	6419256	1	+	27260156	PATU8902	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.6220523304523362	[570]	[824,1481,911,1825]	6	hSpCas9	negative selection	8157852
6419630	6419653	1	+	27260156	PATU8902	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.4882260933517232	[656]	[1214,1559,1614,562]	5	hSpCas9	negative selection	8157853
6419654	6419677	1	+	27260156	PANC1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.18659157501282952	[153]	[183,168,65,61]	-3	hSpCas9	negative selection	8214841
6419130	6419153	1	-	27260156	PANC1	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.28471499019134217	[136]	[104,105,152,191]	4	hSpCas9	negative selection	8214842
6419044	6419067	1	+	27260156	PANC1	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.18062794156900752	[45]	[55,38,37,43]	3	hSpCas9	negative selection	8214843
6419314	6419337	1	+	27260156	PANC1	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.569337683224983	[451]	[673,782,407,483]	8	hSpCas9	negative selection	8279102
6419233	6419256	1	+	27260156	PANC1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.10272999674584296	[570]	[480,598,364,409]	-2	hSpCas9	negative selection	8279103
6419630	6419653	1	+	27260156	PANC1	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.31991611870018377	[656]	[404,696,390,371]	-5	hSpCas9	negative selection	8279104
6419654	6419677	1	+	27260156	PANC0813	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.5571177733238821	[153]	[350,379,124,217]	8	hSpCas9	negative selection	8336092
6419130	6419153	1	-	27260156	PANC0813	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.2422195948015453	[136]	[272,186,231,82]	4	hSpCas9	negative selection	8336093
6419044	6419067	1	+	27260156	PANC0813	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-1.2320420335651563	[45]	[0,6,56,24]	-9	hSpCas9	negative selection	8336094
6419314	6419337	1	+	27260156	PANC0813	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.5755864741982227	[451]	[774,590,1291,521]	8	hSpCas9	negative selection	8400353
6419233	6419256	1	+	27260156	PANC0813	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.04994037579340485	[570]	[997,426,625,575]	-1	hSpCas9	negative selection	8400354
6419630	6419653	1	+	27260156	PANC0813	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.05184111689560961	[656]	[984,669,695,652]	-1	hSpCas9	negative selection	8400355
6419654	6419677	1	+	27260156	RDES	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.49162602247614484	[153]	[120,162,86,123]	-7	hSpCas9	negative selection	8457343
6419130	6419153	1	-	27260156	RDES	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.13233921526521186	[136]	[98,144,182,156]	-2	hSpCas9	negative selection	8457344
6419044	6419067	1	+	27260156	RDES	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-1.0306634738570648	[45]	[21,32,26,19]	-9	hSpCas9	negative selection	8457345
6419314	6419337	1	+	27260156	RDES	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.34071860375174434	[451]	[593,680,648,705]	5	hSpCas9	negative selection	8521604
6419233	6419256	1	+	27260156	RDES	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.31312011128956047	[570]	[639,726,873,1088]	5	hSpCas9	negative selection	8521605
6419630	6419653	1	+	27260156	RDES	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.21705620492806066	[656]	[540,516,869,705]	-4	hSpCas9	negative selection	8521606
6419654	6419677	1	+	27260156	PC3	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.5894170694068805	[153]	[56,169,108,79]	-8	hSpCas9	negative selection	8578594
6419130	6419153	1	-	27260156	PC3	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.13811955486079674	[136]	[54,175,88,182]	-3	hSpCas9	negative selection	8578595
6419044	6419067	1	+	27260156	PC3	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.005624525419232196	[45]	[49,6,17,91]	0	hSpCas9	negative selection	8578596
6419314	6419337	1	+	27260156	PC3	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.021345255604676983	[451]	[273,396,1059,370]	0	hSpCas9	negative selection	8642855
6419233	6419256	1	+	27260156	PC3	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.22059519454290005	[570]	[302,574,1159,934]	5	hSpCas9	negative selection	8642856
6419630	6419653	1	+	27260156	PC3	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.08663181043909435	[656]	[441,399,1073,757]	-2	hSpCas9	negative selection	8642857
6419654	6419677	1	+	27260156	PATU8988T	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.9518040915206647	[153]	[70,101,72,62]	-8	hSpCas9	negative selection	8699845
6419130	6419153	1	-	27260156	PATU8988T	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.3801547249140784	[136]	[196,332,67,101]	6	hSpCas9	negative selection	8699846
6419044	6419067	1	+	27260156	PATU8988T	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.6504099819722708	[45]	[62,33,11,2]	-7	hSpCas9	negative selection	8699847
6419314	6419337	1	+	27260156	PATU8988T	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.11998283813658639	[451]	[451,605,360,494]	2	hSpCas9	negative selection	8764106
6419233	6419256	1	+	27260156	PATU8988T	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.3495495793479861	[570]	[737,710,722,634]	6	hSpCas9	negative selection	8764107
6419630	6419653	1	+	27260156	PATU8988T	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.11266463220486067	[656]	[587,667,446,660]	-2	hSpCas9	negative selection	8764108
6419654	6419677	1	+	27260156	T47D	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.1622736486051568	[153]	[108,161,149,221]	-4	hSpCas9	negative selection	8821096
6419130	6419153	1	-	27260156	T47D	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.017385236206819865	[136]	[186,118,193,148]	0	hSpCas9	negative selection	8821097
6419044	6419067	1	+	27260156	T47D	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.046974071922067484	[45]	[47,48,63,60]	1	hSpCas9	negative selection	8821098
6419314	6419337	1	+	27260156	T47D	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.2496309360898044	[451]	[531,587,652,736]	5	hSpCas9	negative selection	8885357
6419233	6419256	1	+	27260156	T47D	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.16212172666839397	[570]	[746,693,746,794]	3	hSpCas9	negative selection	8885358
6419630	6419653	1	+	27260156	T47D	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.06876264486145389	[656]	[693,632,1020,875]	1	hSpCas9	negative selection	8885359
6419654	6419677	1	+	27260156	SU8686	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.1447459867120695	[153]	[135,102,163,156]	-3	hSpCas9	negative selection	8942347
6419130	6419153	1	-	27260156	SU8686	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.2105780743553034	[136]	[178,109,141,207]	3	hSpCas9	negative selection	8942348
6419044	6419067	1	+	27260156	SU8686	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.3421418045832696	[45]	[12,10,47,85]	-5	hSpCas9	negative selection	8942349
6419314	6419337	1	+	27260156	SU8686	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.09165822497101309	[451]	[484,371,447,639]	1	hSpCas9	negative selection	9006608
6419233	6419256	1	+	27260156	SU8686	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.19769946144577893	[570]	[508,540,732,878]	3	hSpCas9	negative selection	9006609
6419630	6419653	1	+	27260156	SU8686	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.09066672642584384	[656]	[566,537,740,1010]	1	hSpCas9	negative selection	9006610
6419654	6419677	1	+	27260156	SKES1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.35601374456108004	[153]	[116,85,99,165]	-7	hSpCas9	negative selection	9063598
6419130	6419153	1	-	27260156	SKES1	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.030529224404493682	[136]	[212,170,99,92]	0	hSpCas9	negative selection	9063599
6419044	6419067	1	+	27260156	SKES1	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.4122086760835173	[45]	[31,21,30,48]	-7	hSpCas9	negative selection	9063600
6419314	6419337	1	+	27260156	SKES1	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.05544740590008757	[451]	[441,542,513,384]	1	hSpCas9	negative selection	9127859
6419233	6419256	1	+	27260156	SKES1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.05275074829114512	[570]	[856,585,566,405]	1	hSpCas9	negative selection	9127860
6419630	6419653	1	+	27260156	SKES1	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.19499116532653943	[656]	[617,607,594,483]	-4	hSpCas9	negative selection	9127861
6419654	6419677	1	+	27260156	TOV112D	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.00030340307891152385	[153]	[65,235,271,57]	0	hSpCas9	negative selection	9184849
6419130	6419153	1	-	27260156	TOV112D	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.055914217310238934	[136]	[53,291,97,116]	-1	hSpCas9	negative selection	9184850
6419044	6419067	1	+	27260156	TOV112D	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-1.8055287503175488	[45]	[28,11,8,3]	-9	hSpCas9	negative selection	9184851
6419314	6419337	1	+	27260156	TOV112D	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.23971035297628374	[451]	[593,790,417,405]	4	hSpCas9	negative selection	9249110
6419233	6419256	1	+	27260156	TOV112D	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.1332173643383051	[570]	[739,603,591,576]	2	hSpCas9	negative selection	9249111
6419630	6419653	1	+	27260156	TOV112D	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.2753887493104028	[656]	[671,610,440,478]	-5	hSpCas9	negative selection	9249112
6419654	6419677	1	+	27260156	TC71	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.17099817196572542	[153]	[169,175,51,193]	-4	hSpCas9	negative selection	9306100
6419130	6419153	1	-	27260156	TC71	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	0.25004110206928565	[136]	[166,144,116,277]	6	hSpCas9	negative selection	9306101
6419044	6419067	1	+	27260156	TC71	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	-0.44971124605287116	[45]	[29,44,9,61]	-8	hSpCas9	negative selection	9306102
6419314	6419337	1	+	27260156	TC71	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.2769059538606941	[451]	[416,778,603,548]	6	hSpCas9	negative selection	9370361
6419233	6419256	1	+	27260156	TC71	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.1197279398908358	[570]	[714,607,628,710]	3	hSpCas9	negative selection	9370362
6419630	6419653	1	+	27260156	TC71	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	-0.06727527673884931	[656]	[598,735,542,825]	-2	hSpCas9	negative selection	9370363
6419654	6419677	1	+	27260156	TC32	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.21205812376148359	[153]	[129,191,202,133]	4	hSpCas9	negative selection	9427351
6419130	6419153	1	-	27260156	TC32	viability	GCCTTGCGACAGCTACCGCGAGG	HES2	ENSG00000069812	-0.3660912272714907	[136]	[126,17,189,102]	-6	hSpCas9	negative selection	9427352
6419044	6419067	1	+	27260156	TC32	viability	CTCCAGCAGGCGCGCGCTCACGG	HES2	ENSG00000069812	0.5982667122889649	[45]	[77,0,137,77]	8	hSpCas9	negative selection	9427353
6419314	6419337	1	+	27260156	TC32	viability	CTTCTCTAGCTTCGAGCAGTTGG	HES2	ENSG00000069812	0.647481989922305	[451]	[489,665,829,684]	9	hSpCas9	negative selection	9491612
6419233	6419256	1	+	27260156	TC32	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.21897664385160298	[570]	[545,441,934,674]	4	hSpCas9	negative selection	9491613
6419630	6419653	1	+	27260156	TC32	viability	TGAGCCCCTTAAGCTGGCTCAGG	HES2	ENSG00000069812	0.043350961593730974	[656]	[607,467,814,718]	0	hSpCas9	negative selection	9491614
6419031	6419054	1	+	27869803	HPAFII	viability after 27 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.5430773232449716	[271]	[311,121,NaN]	4	hSpCas9	negative selection	9535351
6419129	6419152	1	+	27869803	HPAFII	viability after 27 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.08868052599865306	[145]	[117,33,NaN]	0	hSpCas9	negative selection	9535352
6419129	6419152	1	-	27869803	HPAFII	viability after 27 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.8436063270425636	[290]	[453,124,NaN]	6	hSpCas9	negative selection	9535353
6419222	6419245	1	+	27869803	HPAFII	viability after 27 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.023830520296337143	[490]	[266,242,NaN]	0	hSpCas9	negative selection	9535354
6419654	6419677	1	+	27869803	HPAFII	viability after 27 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.4529503365146784	[168]	[77,53,NaN]	-3	hSpCas9	negative selection	9535355
6419031	6419054	1	+	27869803	HPAFII	viability after 15 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.7267360506042031	[271]	[677,362,NaN]	7	hSpCas9	negative selection	9617800
6419129	6419152	1	+	27869803	HPAFII	viability after 15 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.44509849639348087	[145]	[179,74,NaN]	-5	hSpCas9	negative selection	9617801
6419129	6419152	1	-	27869803	HPAFII	viability after 15 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.36504619973611707	[290]	[506,337,NaN]	4	hSpCas9	negative selection	9617802
6419222	6419245	1	+	27869803	HPAFII	viability after 15 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.25724773373710286	[490]	[938,438,NaN]	3	hSpCas9	negative selection	9617803
6419654	6419677	1	+	27869803	HPAFII	viability after 15 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.035921249353616846	[168]	[274,130,NaN]	0	hSpCas9	negative selection	9617804
6419031	6419054	1	+	27869803	ASPC1	viability after 36 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.9134027677090621	[667]	[439,607,299]	8	hSpCas9	negative selection	9700249
6419129	6419152	1	+	27869803	ASPC1	viability after 36 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.20398464348597367	[397]	[151,125,190]	2	hSpCas9	negative selection	9700250
6419129	6419152	1	-	27869803	ASPC1	viability after 36 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.34247698408859123	[847]	[290,472,352]	3	hSpCas9	negative selection	9700251
6419222	6419245	1	+	27869803	ASPC1	viability after 36 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.6008403081478374	[989]	[612,502,472]	6	hSpCas9	negative selection	9700252
6419654	6419677	1	+	27869803	ASPC1	viability after 36 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.15015176807044184	[370]	[210,101,60]	-1	hSpCas9	negative selection	9700253
6419031	6419054	1	+	27869803	PATU8988S	viability after 35 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.6759109480015641	[560]	[108,173,NaN]	-6	hSpCas9	negative selection	9782698
6419129	6419152	1	+	27869803	PATU8988S	viability after 35 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.3948700368727941	[322]	[189,151,NaN]	4	hSpCas9	negative selection	9782699
6419129	6419152	1	-	27869803	PATU8988S	viability after 35 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.25465562159985144	[849]	[261,311,NaN]	-3	hSpCas9	negative selection	9782700
6419222	6419245	1	+	27869803	PATU8988S	viability after 35 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	-0.25461570540025036	[1258]	[435,413,NaN]	-3	hSpCas9	negative selection	9782701
6419654	6419677	1	+	27869803	PATU8988S	viability after 35 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.06382781645889846	[302]	[150,103,NaN]	0	hSpCas9	negative selection	9782702
6419031	6419054	1	+	27869803	PATU8988S	viability after 31 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	-0.6852253756587433	[560]	[128,151,NaN]	-6	hSpCas9	negative selection	9865147
6419129	6419152	1	+	27869803	PATU8988S	viability after 31 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	0.27198434775426517	[322]	[129,187,NaN]	3	hSpCas9	negative selection	9865148
6419129	6419152	1	-	27869803	PATU8988S	viability after 31 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	-0.1304908557587764	[849]	[218,424,NaN]	-1	hSpCas9	negative selection	9865149
6419222	6419245	1	+	27869803	PATU8988S	viability after 31 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.15114166146775565	[1258]	[483,650,NaN]	2	hSpCas9	negative selection	9865150
6419654	6419677	1	+	27869803	PATU8988S	viability after 31 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.14419741711863432	[302]	[129,137,NaN]	1	hSpCas9	negative selection	9865151
6419031	6419054	1	+	27869803	HPAFII	viability after 35 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.5670790061526277	[271]	[211,194,NaN]	3	hSpCas9	negative selection	9947596
6419129	6419152	1	+	27869803	HPAFII	viability after 35 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-0.6712161782510452	[145]	[52,38,NaN]	-4	hSpCas9	negative selection	9947597
6419129	6419152	1	-	27869803	HPAFII	viability after 35 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.809147560659947	[290]	[394,103,NaN]	5	hSpCas9	negative selection	9947598
6419222	6419245	1	+	27869803	HPAFII	viability after 35 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.24661648816710757	[490]	[340,242,NaN]	1	hSpCas9	negative selection	9947599
6419654	6419677	1	+	27869803	HPAFII	viability after 35 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.5365344858632389	[168]	[26,94,NaN]	-3	hSpCas9	negative selection	9947600
6419031	6419054	1	+	27869803	HPAFII	viability after 31 days	TCCGCCACAGGTGCTCCAGCAGG	HES2	ENSG00000069812	0.5443570151194925	[271]	[269,170,NaN]	4	hSpCas9	negative selection	10030045
6419129	6419152	1	+	27869803	HPAFII	viability after 31 days	CCCTCGCGGTAGCTGTCGCAAGG	HES2	ENSG00000069812	-1.0237454255641545	[145]	[46,32,NaN]	-6	hSpCas9	negative selection	10030046
6419129	6419152	1	-	27869803	HPAFII	viability after 31 days	CCTTGCGACAGCTACCGCGAGGG	HES2	ENSG00000069812	0.6272880179370569	[290]	[380,111,NaN]	4	hSpCas9	negative selection	10030047
6419222	6419245	1	+	27869803	HPAFII	viability after 31 days	GCAGGGAGGGCTCACTCACGGGG	HES2	ENSG00000069812	0.09574084162778984	[490]	[315,270,NaN]	0	hSpCas9	negative selection	10030048
6419654	6419677	1	+	27869803	HPAFII	viability after 31 days	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	-0.10235000694267204	[168]	[84,91,NaN]	0	hSpCas9	negative selection	10030049
6419684	6419707	1	-	28162770	P31FUJ	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-0.8580574110835681	[235]	[152]	-6	hSpCas9	negative selection	10168452
6419803	6419826	1	-	28162770	P31FUJ	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.19565581062678686	[213]	[287]	2	hSpCas9	negative selection	10168453
6419313	6419336	1	-	28162770	P31FUJ	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.4765310874513817	[192]	[162]	-4	hSpCas9	negative selection	10168454
6419654	6419677	1	+	28162770	P31FUJ	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.2452450923902656	[83]	[233]	9	hSpCas9	negative selection	10168455
6419301	6419324	1	-	28162770	P31FUJ	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.9895902169220694	[215]	[503]	9	hSpCas9	negative selection	10168456
6419249	6419272	1	+	28162770	P31FUJ	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.8934958646276756	[234]	[512]	8	hSpCas9	negative selection	10168457
6419602	6419625	1	+	28162770	P31FUJ	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.07093578802227118	[378]	[423]	0	hSpCas9	negative selection	10168458
6419277	6419300	1	-	28162770	P31FUJ	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	1.2128236146978881	[104]	[285]	9	hSpCas9	negative selection	10168459
6419262	6419285	1	+	28162770	P31FUJ	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.6281337578480696	[184]	[335]	7	hSpCas9	negative selection	10168460
6419233	6419256	1	+	28162770	P31FUJ	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.1996353404791793	[85]	[87]	-2	hSpCas9	negative selection	10168461
6419684	6419707	1	-	28162770	TF1	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10337818
6419803	6419826	1	-	28162770	TF1	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10337819
6419313	6419336	1	-	28162770	TF1	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10337820
6419654	6419677	1	+	28162770	TF1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10337821
6419301	6419324	1	-	28162770	TF1	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10337822
6419249	6419272	1	+	28162770	TF1	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10337823
6419602	6419625	1	+	28162770	TF1	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10337824
6419277	6419300	1	-	28162770	TF1	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10337825
6419262	6419285	1	+	28162770	TF1	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10337826
6419233	6419256	1	+	28162770	TF1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10337827
6419684	6419707	1	-	28162770	SKM1	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.8333501305905486	[59]	[188]	7	hSpCas9	negative selection	10507184
6419803	6419826	1	-	28162770	SKM1	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.2154730073966575	[56]	[116]	2	hSpCas9	negative selection	10507185
6419313	6419336	1	-	28162770	SKM1	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.36086235912780507	[36]	[83]	3	hSpCas9	negative selection	10507186
6419654	6419677	1	+	28162770	SKM1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.5650214250872416	[12]	[67]	9	hSpCas9	negative selection	10507187
6419301	6419324	1	-	28162770	SKM1	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.11088410611945743	[65]	[125]	1	hSpCas9	negative selection	10507188
6419249	6419272	1	+	28162770	SKM1	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.05698290101662851	[86]	[159]	0	hSpCas9	negative selection	10507189
6419602	6419625	1	+	28162770	SKM1	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.28802312601965424	[95]	[138]	-2	hSpCas9	negative selection	10507190
6419277	6419300	1	-	28162770	SKM1	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.9853532240355987	[21]	[76]	8	hSpCas9	negative selection	10507191
6419262	6419285	1	+	28162770	SKM1	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.2876227931524926	[37]	[81]	3	hSpCas9	negative selection	10507192
6419233	6419256	1	+	28162770	SKM1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-1.4069641987431616	[14]	[9]	-7	hSpCas9	negative selection	10507193
6419684	6419707	1	-	28162770	SKM1	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.8333501305905486	[59]	[188]	7	hSpCas9	negative selection	10676550
6419803	6419826	1	-	28162770	SKM1	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.2154730073966575	[56]	[116]	2	hSpCas9	negative selection	10676551
6419313	6419336	1	-	28162770	SKM1	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.36086235912780507	[36]	[83]	3	hSpCas9	negative selection	10676552
6419654	6419677	1	+	28162770	SKM1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.5650214250872416	[12]	[67]	9	hSpCas9	negative selection	10676553
6419301	6419324	1	-	28162770	SKM1	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.11088410611945743	[65]	[125]	1	hSpCas9	negative selection	10676554
6419249	6419272	1	+	28162770	SKM1	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.05698290101662851	[86]	[159]	0	hSpCas9	negative selection	10676555
6419602	6419625	1	+	28162770	SKM1	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.28802312601965424	[95]	[138]	-2	hSpCas9	negative selection	10676556
6419277	6419300	1	-	28162770	SKM1	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.9853532240355987	[21]	[76]	8	hSpCas9	negative selection	10676557
6419262	6419285	1	+	28162770	SKM1	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.2876227931524926	[37]	[81]	3	hSpCas9	negative selection	10676558
6419233	6419256	1	+	28162770	SKM1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-1.4069641987431616	[14]	[9]	-7	hSpCas9	negative selection	10676559
6419684	6419707	1	-	28162770	PL21	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.5528928355138214	[212]	[135]	5	hSpCas9	negative selection	10845916
6419803	6419826	1	-	28162770	PL21	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	-0.13328411923587158	[125]	[49]	-1	hSpCas9	negative selection	10845917
6419313	6419336	1	-	28162770	PL21	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.040868485014474765	[155]	[65]	0	hSpCas9	negative selection	10845918
6419654	6419677	1	+	28162770	PL21	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.37006461593163265	[111]	[62]	3	hSpCas9	negative selection	10845919
6419301	6419324	1	-	28162770	PL21	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	1.0186194745684003	[202]	[178]	8	hSpCas9	negative selection	10845920
6419249	6419272	1	+	28162770	PL21	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	-0.3719415949351038	[222]	[74]	-3	hSpCas9	negative selection	10845921
6419602	6419625	1	+	28162770	PL21	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.5904070198817302	[255]	[73]	-4	hSpCas9	negative selection	10845922
6419277	6419300	1	-	28162770	PL21	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	-1.744718831318219	[76]	[9]	-8	hSpCas9	negative selection	10845923
6419262	6419285	1	+	28162770	PL21	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.753883384599756	[108]	[79]	6	hSpCas9	negative selection	10845924
6419233	6419256	1	+	28162770	PL21	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	2.044861389011409	[48]	[87]	9	hSpCas9	negative selection	10845925
6419684	6419707	1	-	28162770	P31FUJ	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-0.8580574110835681	[235]	[152]	-6	hSpCas9	negative selection	11015282
6419803	6419826	1	-	28162770	P31FUJ	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.19565581062678686	[213]	[287]	2	hSpCas9	negative selection	11015283
6419313	6419336	1	-	28162770	P31FUJ	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.4765310874513817	[192]	[162]	-4	hSpCas9	negative selection	11015284
6419654	6419677	1	+	28162770	P31FUJ	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.2452450923902656	[83]	[233]	9	hSpCas9	negative selection	11015285
6419301	6419324	1	-	28162770	P31FUJ	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.9895902169220694	[215]	[503]	9	hSpCas9	negative selection	11015286
6419249	6419272	1	+	28162770	P31FUJ	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.8934958646276756	[234]	[512]	8	hSpCas9	negative selection	11015287
6419602	6419625	1	+	28162770	P31FUJ	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.07093578802227118	[378]	[423]	0	hSpCas9	negative selection	11015288
6419277	6419300	1	-	28162770	P31FUJ	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	1.2128236146978881	[104]	[285]	9	hSpCas9	negative selection	11015289
6419262	6419285	1	+	28162770	P31FUJ	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.6281337578480696	[184]	[335]	7	hSpCas9	negative selection	11015290
6419233	6419256	1	+	28162770	P31FUJ	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.1996353404791793	[85]	[87]	-2	hSpCas9	negative selection	11015291
6419684	6419707	1	-	28162770	OCIAML5	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-1.1780528823257128	[88]	[70]	-6	hSpCas9	negative selection	11184648
6419803	6419826	1	-	28162770	OCIAML5	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.483536460920442	[83]	[211]	4	hSpCas9	negative selection	11184649
6419313	6419336	1	-	28162770	OCIAML5	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.33235800027343043	[87]	[199]	3	hSpCas9	negative selection	11184650
6419654	6419677	1	+	28162770	OCIAML5	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.0118718795599748	[24]	[90]	8	hSpCas9	negative selection	11184651
6419301	6419324	1	-	28162770	OCIAML5	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.9764529611916491	[115]	[411]	8	hSpCas9	negative selection	11184652
6419249	6419272	1	+	28162770	OCIAML5	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.00239258632064987	[98]	[178]	0	hSpCas9	negative selection	11184653
6419602	6419625	1	+	28162770	OCIAML5	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.10964138630000175	[210]	[352]	-1	hSpCas9	negative selection	11184654
6419277	6419300	1	-	28162770	OCIAML5	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.20407650717353676	[62]	[130]	1	hSpCas9	negative selection	11184655
6419262	6419285	1	+	28162770	OCIAML5	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	-0.36318004169788826	[118]	[166]	-3	hSpCas9	negative selection	11184656
6419233	6419256	1	+	28162770	OCIAML5	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.9929291067038466	[42]	[38]	-6	hSpCas9	negative selection	11184657
6419684	6419707	1	-	28162770	EOL1	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.19329582859872219	[419]	[252]	1	hSpCas9	negative selection	11354014
6419803	6419826	1	-	28162770	EOL1	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	1.2008124872568473	[198]	[240]	8	hSpCas9	negative selection	11354015
6419313	6419336	1	-	28162770	EOL1	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.12952890118525814	[298]	[143]	-1	hSpCas9	negative selection	11354016
6419654	6419677	1	+	28162770	EOL1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.0581309259491265	[133]	[146]	8	hSpCas9	negative selection	11354017
6419301	6419324	1	-	28162770	EOL1	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	1.017178749480799	[376]	[401]	8	hSpCas9	negative selection	11354018
6419249	6419272	1	+	28162770	EOL1	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	-0.07545222842946542	[481]	[240]	0	hSpCas9	negative selection	11354019
6419602	6419625	1	+	28162770	EOL1	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.2801717853423795	[346]	[221]	2	hSpCas9	negative selection	11354020
6419277	6419300	1	-	28162770	EOL1	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.997920957900754	[114]	[120]	8	hSpCas9	negative selection	11354021
6419262	6419285	1	+	28162770	EOL1	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	-1.6604147291506215	[179]	[29]	-8	hSpCas9	negative selection	11354022
6419233	6419256	1	+	28162770	EOL1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.1198463477879188	[65]	[31]	-1	hSpCas9	negative selection	11354023
6419684	6419707	1	-	28162770	MOLM13	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-0.037809840651923846	[300]	[211]	0	hSpCas9	negative selection	11523380
6419803	6419826	1	-	28162770	MOLM13	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.551790639153524	[166]	[176]	4	hSpCas9	negative selection	11523381
6419313	6419336	1	-	28162770	MOLM13	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	1.054932192706782	[230]	[346]	7	hSpCas9	negative selection	11523382
6419654	6419677	1	+	28162770	MOLM13	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.520838261493538	[106]	[110]	4	hSpCas9	negative selection	11523383
6419301	6419324	1	-	28162770	MOLM13	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	1.1046543125003028	[309]	[481]	8	hSpCas9	negative selection	11523384
6419249	6419272	1	+	28162770	MOLM13	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	1.6704591461144784	[334]	[770]	9	hSpCas9	negative selection	11523385
6419602	6419625	1	+	28162770	MOLM13	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.6215457020373658	[365]	[171]	-4	hSpCas9	negative selection	11523386
6419277	6419300	1	-	28162770	MOLM13	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	0.3388474365428399	[186]	[170]	2	hSpCas9	negative selection	11523387
6419262	6419285	1	+	28162770	MOLM13	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.11794691048761996	[194]	[152]	0	hSpCas9	negative selection	11523388
6419233	6419256	1	+	28162770	MOLM13	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-0.6264380010035744	[78]	[36]	-4	hSpCas9	negative selection	11523389
6419684	6419707	1	-	28162770	HEL	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.2989804890887794	[282]	[222]	2	hSpCas9	negative selection	11692746
6419803	6419826	1	-	28162770	HEL	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.33209654465950955	[190]	[153]	2	hSpCas9	negative selection	11692747
6419313	6419336	1	-	28162770	HEL	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.15494499028619899	[243]	[173]	1	hSpCas9	negative selection	11692748
6419654	6419677	1	+	28162770	HEL	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	1.904406402070245	[87]	[210]	9	hSpCas9	negative selection	11692749
6419301	6419324	1	-	28162770	HEL	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.7419484359282562	[294]	[315]	6	hSpCas9	negative selection	11692750
6419249	6419272	1	+	28162770	HEL	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.18039561794315656	[309]	[224]	1	hSpCas9	negative selection	11692751
6419602	6419625	1	+	28162770	HEL	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-1.6476536894538987	[361]	[73]	-7	hSpCas9	negative selection	11692752
6419277	6419300	1	-	28162770	HEL	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	1.8110758365394772	[100]	[226]	9	hSpCas9	negative selection	11692753
6419262	6419285	1	+	28162770	HEL	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.34055467241140946	[126]	[102]	3	hSpCas9	negative selection	11692754
6419233	6419256	1	+	28162770	HEL	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	1.1597972682197097	[57]	[82]	8	hSpCas9	negative selection	11692755
6419684	6419707	1	-	28162770	MV411	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-0.6709486836635727	[188]	[99]	-5	hSpCas9	negative selection	11862112
6419803	6419826	1	-	28162770	MV411	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.1405223468662633	[125]	[116]	1	hSpCas9	negative selection	11862113
6419313	6419336	1	-	28162770	MV411	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-0.05474660880617199	[126]	[102]	0	hSpCas9	negative selection	11862114
6419654	6419677	1	+	28162770	MV411	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.15122223552347214	[92]	[86]	1	hSpCas9	negative selection	11862115
6419301	6419324	1	-	28162770	MV411	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.5768993183555451	[190]	[239]	5	hSpCas9	negative selection	11862116
6419249	6419272	1	+	28162770	MV411	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.21166641976095335	[244]	[238]	1	hSpCas9	negative selection	11862117
6419602	6419625	1	+	28162770	MV411	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.7466858828805554	[244]	[122]	-5	hSpCas9	negative selection	11862118
6419277	6419300	1	-	28162770	MV411	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	1.2130860459919983	[84]	[165]	9	hSpCas9	negative selection	11862119
6419262	6419285	1	+	28162770	MV411	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	1.7029682340801688	[100]	[276]	9	hSpCas9	negative selection	11862120
6419233	6419256	1	+	28162770	MV411	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.2684991663106051	[67]	[68]	2	hSpCas9	negative selection	11862121
6419684	6419707	1	-	28162770	MONOMAC1	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	1.7679567031125334	[145]	[569]	9	hSpCas9	negative selection	12031478
6419803	6419826	1	-	28162770	MONOMAC1	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	2.056474784655734	[94]	[452]	9	hSpCas9	negative selection	12031479
6419313	6419336	1	-	28162770	MONOMAC1	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	0.3512671830827543	[92]	[135]	3	hSpCas9	negative selection	12031480
6419654	6419677	1	+	28162770	MONOMAC1	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.1248912478278087	[59]	[74]	1	hSpCas9	negative selection	12031481
6419301	6419324	1	-	28162770	MONOMAC1	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.18071963613983077	[146]	[190]	1	hSpCas9	negative selection	12031482
6419249	6419272	1	+	28162770	MONOMAC1	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	0.35706468995684193	[125]	[184]	3	hSpCas9	negative selection	12031483
6419602	6419625	1	+	28162770	MONOMAC1	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	-0.1503436116115123	[151]	[156]	-1	hSpCas9	negative selection	12031484
6419277	6419300	1	-	28162770	MONOMAC1	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	-0.5631647458574509	[57]	[44]	-5	hSpCas9	negative selection	12031485
6419262	6419285	1	+	28162770	MONOMAC1	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.6603587574976459	[84]	[153]	6	hSpCas9	negative selection	12031486
6419233	6419256	1	+	28162770	MONOMAC1	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.2821309896390056	[32]	[45]	3	hSpCas9	negative selection	12031487
6419684	6419707	1	-	28162770	OCIAML2	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	0.529370174757839	[35]	[287]	5	hSpCas9	negative selection	12200844
6419803	6419826	1	-	28162770	OCIAML2	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	0.5771233062062069	[25]	[214]	5	hSpCas9	negative selection	12200845
6419313	6419336	1	-	28162770	OCIAML2	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	1.4616833672462644	[14]	[228]	9	hSpCas9	negative selection	12200846
6419654	6419677	1	+	28162770	OCIAML2	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.6707260240033803	[16]	[149]	6	hSpCas9	negative selection	12200847
6419301	6419324	1	-	28162770	OCIAML2	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.9458612711781813	[30]	[330]	8	hSpCas9	negative selection	12200848
6419249	6419272	1	+	28162770	OCIAML2	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	1.208850274263285	[31]	[409]	9	hSpCas9	negative selection	12200849
6419602	6419625	1	+	28162770	OCIAML2	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.5390853295910507	[36]	[297]	5	hSpCas9	negative selection	12200850
6419277	6419300	1	-	28162770	OCIAML2	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	-0.0892007186061371	[18]	[98]	0	hSpCas9	negative selection	12200851
6419262	6419285	1	+	28162770	OCIAML2	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	0.12762949809245291	[35]	[217]	1	hSpCas9	negative selection	12200852
6419233	6419256	1	+	28162770	OCIAML2	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	0.014797001928080533	[4]	[27]	0	hSpCas9	negative selection	12200853
6419684	6419707	1	-	28162770	OCIAML3	viability	GCAGAGCCTGAAGCCGCTGCTGG	HES2	ENSG00000069812	-0.05026780232951994	[70]	[206]	0	hSpCas9	negative selection	12370210
6419803	6419826	1	-	28162770	OCIAML3	viability	GGAGCATGGGGCTGCCTCGCCGG	HES2	ENSG00000069812	-1.347367672741038	[58]	[69]	-7	hSpCas9	negative selection	12370211
6419313	6419336	1	-	28162770	OCIAML3	viability	CAACTGCTCGAAGCTAGAGAAGG	HES2	ENSG00000069812	-1.8794098591864112	[38]	[31]	-8	hSpCas9	negative selection	12370212
6419654	6419677	1	+	28162770	OCIAML3	viability	TCTGGTTGATGCGCGCGCGCCGG	HES2	ENSG00000069812	0.7415953914602755	[20]	[105]	6	hSpCas9	negative selection	12370213
6419301	6419324	1	-	28162770	OCIAML3	viability	GCTAGAGAAGGCAGACGTCCTGG	HES2	ENSG00000069812	0.29705798812267276	[54]	[203]	3	hSpCas9	negative selection	12370214
6419249	6419272	1	+	28162770	OCIAML3	viability	GCCGTGGGCCATGAGGACGCAGG	HES2	ENSG00000069812	-0.5940076403241631	[66]	[133]	-4	hSpCas9	negative selection	12370215
6419602	6419625	1	+	28162770	OCIAML3	viability	CTCACCTCCCGGCCCAGCAGCGG	HES2	ENSG00000069812	0.09268474736081944	[72]	[234]	0	hSpCas9	negative selection	12370216
6419277	6419300	1	-	28162770	OCIAML3	viability	AATGACCGTGCGCTTCCTGCAGG	HES2	ENSG00000069812	-0.1717746396411155	[24]	[66]	-1	hSpCas9	negative selection	12370217
6419262	6419285	1	+	28162770	OCIAML3	viability	AGGACGCAGGCAGCTCCTGCAGG	HES2	ENSG00000069812	1.0689573723982662	[38]	[246]	8	hSpCas9	negative selection	12370218
6419233	6419256	1	+	28162770	OCIAML3	viability	TCACTCACGGGGCGCTGCCGTGG	HES2	ENSG00000069812	-1.313899721131428	[13]	[16]	-7	hSpCas9	negative selection	12370219