Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 138050
• Symbol: HGSNAT
• Description: heparan-alpha-glucosaminide N-acetyltransferase

DataSource: http://genomecrispr.dkfz.de/#!/results/HGSNAT

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43140605	43140628	8	-	26472758	Jiyoye	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.23815973719476455	[121]	[77]	-2	hSpCas9	negative selection	70520
43172329	43172352	8	+	26472758	Jiyoye	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	1.2234634283334853	[45]	[80]	7	hSpCas9	negative selection	70521
43170611	43170634	8	-	26472758	Jiyoye	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	0.8578367905154387	[29]	[40]	6	hSpCas9	negative selection	70522
43170668	43170691	8	-	26472758	Jiyoye	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	1.089985205625174	[75]	[121]	7	hSpCas9	negative selection	70523
43193753	43193776	8	+	26472758	Jiyoye	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.5441562843332703	[250]	[275]	4	hSpCas9	negative selection	70524
43193772	43193795	8	+	26472758	Jiyoye	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.5253568078541875	[163]	[177]	4	hSpCas9	negative selection	70525
43191548	43191571	8	-	26472758	Jiyoye	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.926825545682064	[299]	[118]	-6	hSpCas9	negative selection	70526
43191569	43191592	8	-	26472758	Jiyoye	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.2145303035634778	[39]	[34]	1	hSpCas9	negative selection	70527
43140570	43140593	8	-	26472758	Jiyoye	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.6649731389735201	[45]	[54]	5	hSpCas9	negative selection	70528
43158655	43158678	8	-	26472758	Jiyoye	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.3140659771143919	[15]	[14]	2	hSpCas9	negative selection	70529
43140605	43140628	8	-	26472758	KBM7	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.9487034110978987	[481,512]	[118,124]	-6	hSpCas9	negative selection	261638
43172329	43172352	8	+	26472758	KBM7	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.8700788284349967	[320,282]	[133,370]	8	hSpCas9	negative selection	261639
43170611	43170634	8	-	26472758	KBM7	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-1.4641282140905387	[177,226]	[51,19]	-8	hSpCas9	negative selection	261640
43170668	43170691	8	-	26472758	KBM7	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.8998528641290066	[789,454]	[137,166]	-6	hSpCas9	negative selection	261641
43193753	43193776	8	+	26472758	KBM7	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	-0.08963808770115955	[1040,773]	[426,369]	-1	hSpCas9	negative selection	261642
43193772	43193795	8	+	26472758	KBM7	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.046901118553831944	[683,415]	[227,291]	0	hSpCas9	negative selection	261643
43191548	43191571	8	-	26472758	KBM7	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.49623054797794536	[793,875]	[335,231]	-4	hSpCas9	negative selection	261644
43191569	43191592	8	-	26472758	KBM7	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.18704376138691892	[151,130]	[55,92]	2	hSpCas9	negative selection	261645
43140570	43140593	8	-	26472758	KBM7	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	-0.060674979012925956	[198,97]	[65,63]	0	hSpCas9	negative selection	261646
43158655	43158678	8	-	26472758	KBM7	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.20840082675599647	[91,139]	[89,41]	2	hSpCas9	negative selection	261647
43140605	43140628	8	-	26472758	Raji	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.3789294410629108	[168]	[50]	3	hSpCas9	negative selection	452756
43172329	43172352	8	+	26472758	Raji	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.29860882430223723	[211]	[39]	-3	hSpCas9	negative selection	452757
43170611	43170634	8	-	26472758	Raji	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.8926164646264005	[151]	[18]	-6	hSpCas9	negative selection	452758
43170668	43170691	8	-	26472758	Raji	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.1500879863278377	[232]	[59]	1	hSpCas9	negative selection	452759
43193753	43193776	8	+	26472758	Raji	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	1.1751989196011712	[373]	[195]	8	hSpCas9	negative selection	452760
43193772	43193795	8	+	26472758	Raji	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.46930969819288093	[248]	[79]	4	hSpCas9	negative selection	452761
43191548	43191571	8	-	26472758	Raji	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	0.46583750628607595	[311]	[99]	4	hSpCas9	negative selection	452762
43191569	43191592	8	-	26472758	Raji	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.01992069412325992	[84]	[19]	0	hSpCas9	negative selection	452763
43140570	43140593	8	-	26472758	Raji	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.28635367641891873	[105]	[29]	2	hSpCas9	negative selection	452764
43158655	43158678	8	-	26472758	Raji	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.17801868348864858	[38]	[7]	-1	hSpCas9	negative selection	452765
43140605	43140628	8	-	26472758	K562	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.13680975357985023	[319]	[296]	1	hSpCas9	negative selection	643874
43172329	43172352	8	+	26472758	K562	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	1.1989191795197987	[305]	[592]	8	hSpCas9	negative selection	643875
43170611	43170634	8	-	26472758	K562	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	0.5093158775174305	[128]	[154]	4	hSpCas9	negative selection	643876
43170668	43170691	8	-	26472758	K562	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.019854574800705682	[465]	[387]	0	hSpCas9	negative selection	643877
43193753	43193776	8	+	26472758	K562	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.3104071372478895	[640]	[670]	2	hSpCas9	negative selection	643878
43193772	43193795	8	+	26472758	K562	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.7744254531483974	[436]	[630]	6	hSpCas9	negative selection	643879
43191548	43191571	8	-	26472758	K562	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.035874878512951736	[554]	[456]	0	hSpCas9	negative selection	643880
43191569	43191592	8	-	26472758	K562	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-0.5316852604067175	[136]	[79]	-3	hSpCas9	negative selection	643881
43140570	43140593	8	-	26472758	K562	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.5035059489835778	[121]	[145]	4	hSpCas9	negative selection	643882
43158655	43158678	8	-	26472758	K562	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.43129686238995646	[93]	[106]	3	hSpCas9	negative selection	643883
43158989	43159012	8	+	26627737	DLD1	viability	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.05939601652803295	[396]	[181,184,9]	0	hSpCas9	negative selection	839659
43170668	43170691	8	-	26627737	DLD1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.0460752505506139	[870]	[307,304,237]	0	hSpCas9	negative selection	839660
43173739	43173762	8	-	26627737	DLD1	viability	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.8990198975011536	[158]	[80,83,109]	8	hSpCas9	negative selection	839661
43178112	43178135	8	+	26627737	DLD1	viability	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.1741585452968416	[825]	[218,279,194]	-2	hSpCas9	negative selection	839662
43182237	43182260	8	-	26627737	DLD1	viability	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	-0.2426790354631173	[276]	[98,49,69]	-3	hSpCas9	negative selection	839663
43191582	43191605	8	-	26627737	DLD1	viability	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.875650889307279	[381]	[199,301,166]	8	hSpCas9	negative selection	839664
43158989	43159012	8	+	26627737	GBM cells	viability after 5 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.45631422915785463	[251]	[87,108]	-6	hSpCas9	negative selection	921974
43170668	43170691	8	-	26627737	GBM cells	viability after 5 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.186994199289375	[275]	[131,204]	3	hSpCas9	negative selection	921975
43173739	43173762	8	-	26627737	GBM cells	viability after 5 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.4968154313143398	[110]	[99,67]	7	hSpCas9	negative selection	921976
43178112	43178135	8	+	26627737	GBM cells	viability after 5 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.5513383169772164	[469]	[151,191]	-7	hSpCas9	negative selection	921977
43182237	43182260	8	-	26627737	GBM cells	viability after 5 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.3790801855952319	[156]	[117,100]	6	hSpCas9	negative selection	921978
43191582	43191605	8	-	26627737	GBM cells	viability after 5 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.438121112391885	[311]	[124,121]	-6	hSpCas9	negative selection	921979
43158989	43159012	8	+	26627737	GBM cells	viability after 13 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.4188048417422069	[251]	[109,95]	-5	hSpCas9	negative selection	1004289
43170668	43170691	8	-	26627737	GBM cells	viability after 13 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.1405974305291853	[275]	[174,103]	-2	hSpCas9	negative selection	1004290
43173739	43173762	8	-	26627737	GBM cells	viability after 13 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.8462044295831875	[110]	[99,114]	8	hSpCas9	negative selection	1004291
43178112	43178135	8	+	26627737	GBM cells	viability after 13 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.5001464693772247	[469]	[160,195]	-5	hSpCas9	negative selection	1004292
43182237	43182260	8	-	26627737	GBM cells	viability after 13 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.04256779577169367	[156]	[111,67]	0	hSpCas9	negative selection	1004293
43191582	43191605	8	-	26627737	GBM cells	viability after 13 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.16707381331956195	[311]	[179,126]	-2	hSpCas9	negative selection	1004294
43158989	43159012	8	+	26627737	GBM cells	viability after 21 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.1926963380722399	[251]	[112,125]	-2	hSpCas9	negative selection	1086604
43170668	43170691	8	-	26627737	GBM cells	viability after 21 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.49083142423421017	[275]	[193,225]	5	hSpCas9	negative selection	1086605
43173739	43173762	8	-	26627737	GBM cells	viability after 21 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.0605506746551223	[110]	[130,120]	9	hSpCas9	negative selection	1086606
43178112	43178135	8	+	26627737	GBM cells	viability after 21 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.41574510245716423	[469]	[372,310]	4	hSpCas9	negative selection	1086607
43182237	43182260	8	-	26627737	GBM cells	viability after 21 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.1692386038823735	[156]	[97,93]	1	hSpCas9	negative selection	1086608
43191582	43191605	8	-	26627737	GBM cells	viability after 21 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.019258597293706825	[311]	[172,161]	0	hSpCas9	negative selection	1086609
43158989	43159012	8	+	26627737	RPE1	viability after 9 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.052585178035367525	[878]	[153,408]	0	hSpCas9	negative selection	1168919
43170668	43170691	8	-	26627737	RPE1	viability after 9 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.3047711175761794	[607]	[140,170]	-2	hSpCas9	negative selection	1168920
43173739	43173762	8	-	26627737	RPE1	viability after 9 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.3667020707621993	[251]	[178,234]	7	hSpCas9	negative selection	1168921
43178112	43178135	8	+	26627737	RPE1	viability after 9 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.1317085387204912	[929]	[311,327]	0	hSpCas9	negative selection	1168922
43182237	43182260	8	-	26627737	RPE1	viability after 9 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	1.6218464861129023	[340]	[266,407]	8	hSpCas9	negative selection	1168923
43191582	43191605	8	-	26627737	RPE1	viability after 9 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.3082774932443128	[1192]	[243,375]	-2	hSpCas9	negative selection	1168924
43158989	43159012	8	+	26627737	RPE1	viability after 12 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.5974132527172381	[878]	[175,134]	-4	hSpCas9	negative selection	1251234
43170668	43170691	8	-	26627737	RPE1	viability after 12 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.28356517335793185	[607]	[192,204]	2	hSpCas9	negative selection	1251235
43173739	43173762	8	-	26627737	RPE1	viability after 12 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.378028884058013	[251]	[259,86]	7	hSpCas9	negative selection	1251236
43178112	43178135	8	+	26627737	RPE1	viability after 12 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.12203264448983225	[929]	[217,328]	0	hSpCas9	negative selection	1251237
43182237	43182260	8	-	26627737	RPE1	viability after 12 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.9630717528828258	[340]	[198,156]	6	hSpCas9	negative selection	1251238
43191582	43191605	8	-	26627737	RPE1	viability after 12 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.30285064422251695	[1192]	[185,337]	-2	hSpCas9	negative selection	1251239
43158989	43159012	8	+	26627737	RPE1	viability after 15 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.34691229288326675	[878]	[138,249]	-2	hSpCas9	negative selection	1333549
43170668	43170691	8	-	26627737	RPE1	viability after 15 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.20885410030872403	[607]	[182,213]	1	hSpCas9	negative selection	1333550
43173739	43173762	8	-	26627737	RPE1	viability after 15 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.7083048362101612	[251]	[207,256]	8	hSpCas9	negative selection	1333551
43178112	43178135	8	+	26627737	RPE1	viability after 15 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.06459056799656593	[929]	[211,335]	0	hSpCas9	negative selection	1333552
43182237	43182260	8	-	26627737	RPE1	viability after 15 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	1.0148150536972826	[340]	[255,135]	6	hSpCas9	negative selection	1333553
43191582	43191605	8	-	26627737	RPE1	viability after 15 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.46460509350817414	[1192]	[156,328]	-3	hSpCas9	negative selection	1333554
43158989	43159012	8	+	26627737	RPE1	viability after 18 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.00448482641803441	[878]	[162,314]	0	hSpCas9	negative selection	1415864
43170668	43170691	8	-	26627737	RPE1	viability after 18 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.16793864441178497	[607]	[164,204]	1	hSpCas9	negative selection	1415865
43173739	43173762	8	-	26627737	RPE1	viability after 18 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.4224353113133406	[251]	[175,188]	7	hSpCas9	negative selection	1415866
43178112	43178135	8	+	26627737	RPE1	viability after 18 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.4113026889549645	[929]	[297,371]	2	hSpCas9	negative selection	1415867
43182237	43182260	8	-	26627737	RPE1	viability after 18 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	1.6988752852052946	[340]	[247,352]	8	hSpCas9	negative selection	1415868
43191582	43191605	8	-	26627737	RPE1	viability after 18 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.19152245345263957	[1192]	[206,361]	-1	hSpCas9	negative selection	1415869
43158989	43159012	8	+	26627737	HeLa	viability after 8 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-1.0651437117071785	[471]	[48,111,120]	-8	hSpCas9	negative selection	1498179
43170668	43170691	8	-	26627737	HeLa	viability after 8 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.9114706341880099	[880]	[192,344,79]	-7	hSpCas9	negative selection	1498180
43173739	43173762	8	-	26627737	HeLa	viability after 8 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.4607149950855579	[256]	[65,86,86]	-4	hSpCas9	negative selection	1498181
43178112	43178135	8	+	26627737	HeLa	viability after 8 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.46264057027919575	[695]	[195,177,275]	-4	hSpCas9	negative selection	1498182
43182237	43182260	8	-	26627737	HeLa	viability after 8 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.5719424553192254	[318]	[195,232,188]	5	hSpCas9	negative selection	1498183
43191582	43191605	8	-	26627737	HeLa	viability after 8 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.23606461418588426	[403]	[220,158,87]	-2	hSpCas9	negative selection	1498184
43158989	43159012	8	+	26627737	HeLa	viability after 12 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.5158528488895573	[471]	[235,52,131]	-4	hSpCas9	negative selection	1580494
43170668	43170691	8	-	26627737	HeLa	viability after 12 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.6216698368953633	[880]	[260,194,258]	-5	hSpCas9	negative selection	1580495
43173739	43173762	8	-	26627737	HeLa	viability after 12 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.6158720151297538	[256]	[84,96,310]	5	hSpCas9	negative selection	1580496
43178112	43178135	8	+	26627737	HeLa	viability after 12 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.7814701871329708	[695]	[100,186,209]	-6	hSpCas9	negative selection	1580497
43182237	43182260	8	-	26627737	HeLa	viability after 12 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.11990196500711367	[318]	[157,163,105]	1	hSpCas9	negative selection	1580498
43191582	43191605	8	-	26627737	HeLa	viability after 12 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.10449366826014517	[403]	[112,316,91]	0	hSpCas9	negative selection	1580499
43158989	43159012	8	+	26627737	HeLa	viability after 15 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.8687008203452877	[471]	[94,40,185]	-6	hSpCas9	negative selection	1662809
43170668	43170691	8	-	26627737	HeLa	viability after 15 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.6321499421976524	[880]	[247,238,204]	-5	hSpCas9	negative selection	1662810
43173739	43173762	8	-	26627737	HeLa	viability after 15 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.4104283348896403	[256]	[101,123,195]	3	hSpCas9	negative selection	1662811
43178112	43178135	8	+	26627737	HeLa	viability after 15 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-1.3859151129561962	[695]	[19,69,246]	-8	hSpCas9	negative selection	1662812
43182237	43182260	8	-	26627737	HeLa	viability after 15 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.7881321698400785	[318]	[179,236,258]	6	hSpCas9	negative selection	1662813
43191582	43191605	8	-	26627737	HeLa	viability after 15 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.6072952406065097	[403]	[250,257,241]	5	hSpCas9	negative selection	1662814
43158989	43159012	8	+	26627737	HeLa	viability after 18 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.856776523534998	[471]	[66,31,185]	-6	hSpCas9	negative selection	1745124
43170668	43170691	8	-	26627737	HeLa	viability after 18 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.6172228453607328	[880]	[170,197,204]	-5	hSpCas9	negative selection	1745125
43173739	43173762	8	-	26627737	HeLa	viability after 18 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.39013088589069617	[256]	[69,95,195]	3	hSpCas9	negative selection	1745126
43178112	43178135	8	+	26627737	HeLa	viability after 18 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-1.3776530736555461	[695]	[12,59,246]	-8	hSpCas9	negative selection	1745127
43182237	43182260	8	-	26627737	HeLa	viability after 18 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.835091151487634	[318]	[128,203,258]	6	hSpCas9	negative selection	1745128
43191582	43191605	8	-	26627737	HeLa	viability after 18 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.6169799195709375	[403]	[172,211,241]	5	hSpCas9	negative selection	1745129
43158989	43159012	8	+	26627737	HCT116	viability after 6 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-1.6959372931912005	[511]	[29,21]	-7	hSpCas9	negative selection	1827439
43170668	43170691	8	-	26627737	HCT116	viability after 6 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	1.0342729536605972	[926]	[146,381]	5	hSpCas9	negative selection	1827440
43173739	43173762	8	-	26627737	HCT116	viability after 6 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.86252169189047	[121]	[139,30]	8	hSpCas9	negative selection	1827441
43178112	43178135	8	+	26627737	HCT116	viability after 6 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	1.5339385773204124	[976]	[942,169]	7	hSpCas9	negative selection	1827442
43182237	43182260	8	-	26627737	HCT116	viability after 6 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.971657971796081	[392]	[222,64]	5	hSpCas9	negative selection	1827443
43191582	43191605	8	-	26627737	HCT116	viability after 6 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.08379352699680248	[433]	[90,61]	0	hSpCas9	negative selection	1827444
43158989	43159012	8	+	26627737	HCT116	viability after 8 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.5770729297957946	[313]	[99,159,87]	-6	hSpCas9	negative selection	1909754
43170668	43170691	8	-	26627737	HCT116	viability after 8 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.23310060552625278	[539]	[132,260,361]	-3	hSpCas9	negative selection	1909755
43173739	43173762	8	-	26627737	HCT116	viability after 8 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.927665790774505	[181]	[42,62,51]	-8	hSpCas9	negative selection	1909756
43178112	43178135	8	+	26627737	HCT116	viability after 8 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.7297054720505689	[595]	[164,268,159]	-7	hSpCas9	negative selection	1909757
43182237	43182260	8	-	26627737	HCT116	viability after 8 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.4387221762387933	[152]	[133,163,45]	4	hSpCas9	negative selection	1909758
43191582	43191605	8	-	26627737	HCT116	viability after 8 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.5466618129730357	[183]	[217,116,110]	5	hSpCas9	negative selection	1909759
43158989	43159012	8	+	26627737	HCT116	viability after 9 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-1.0328060013197922	[511]	[120,23]	-6	hSpCas9	negative selection	1992069
43170668	43170691	8	-	26627737	HCT116	viability after 9 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.09644964760491859	[926]	[372,178]	0	hSpCas9	negative selection	1992070
43173739	43173762	8	-	26627737	HCT116	viability after 9 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	1.6512578038653376	[121]	[165,51]	8	hSpCas9	negative selection	1992071
43178112	43178135	8	+	26627737	HCT116	viability after 9 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.49848984428426213	[976]	[348,383]	3	hSpCas9	negative selection	1992072
43182237	43182260	8	-	26627737	HCT116	viability after 9 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	-0.18082038235442688	[392]	[191,13]	-1	hSpCas9	negative selection	1992073
43191582	43191605	8	-	26627737	HCT116	viability after 9 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.39256271133061754	[433]	[107,186]	3	hSpCas9	negative selection	1992074
43158989	43159012	8	+	26627737	HCT116	viability after 12 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.25553498288878096	[313]	[143,171,98]	-3	hSpCas9	negative selection	2074384
43170668	43170691	8	-	26627737	HCT116	viability after 12 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.42554766820355405	[539]	[296,346,505]	4	hSpCas9	negative selection	2074385
43173739	43173762	8	-	26627737	HCT116	viability after 12 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.5274325138272971	[181]	[75,56,64]	-5	hSpCas9	negative selection	2074386
43178112	43178135	8	+	26627737	HCT116	viability after 12 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.49716576066741136	[595]	[142,276,253]	-5	hSpCas9	negative selection	2074387
43182237	43182260	8	-	26627737	HCT116	viability after 12 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.498688993823245	[152]	[114,125,99]	5	hSpCas9	negative selection	2074388
43191582	43191605	8	-	26627737	HCT116	viability after 12 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	1.1867359347456552	[183]	[129,373,167]	8	hSpCas9	negative selection	2074389
43158989	43159012	8	+	26627737	HCT116	viability after 15 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.4468823665291481	[313]	[161,147,90]	-4	hSpCas9	negative selection	2156699
43170668	43170691	8	-	26627737	HCT116	viability after 15 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.10012621090422313	[539]	[348,297,351]	1	hSpCas9	negative selection	2156700
43173739	43173762	8	-	26627737	HCT116	viability after 15 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.10278980334294718	[181]	[204,29,112]	1	hSpCas9	negative selection	2156701
43178112	43178135	8	+	26627737	HCT116	viability after 15 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.6536062039513492	[595]	[136,209,294]	-6	hSpCas9	negative selection	2156702
43182237	43182260	8	-	26627737	HCT116	viability after 15 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.12222518321499654	[152]	[125,101,62]	1	hSpCas9	negative selection	2156703
43191582	43191605	8	-	26627737	HCT116	viability after 15 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.8999938651702725	[183]	[256,240,101]	7	hSpCas9	negative selection	2156704
43158989	43159012	8	+	26627737	HCT116	viability after 18 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	0.09057099594201455	[313]	[305,75,105]	0	hSpCas9	negative selection	2239014
43170668	43170691	8	-	26627737	HCT116	viability after 18 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.21577511417950712	[539]	[116,280,274]	-2	hSpCas9	negative selection	2239015
43173739	43173762	8	-	26627737	HCT116	viability after 18 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.16776496744550962	[181]	[93,70,134]	1	hSpCas9	negative selection	2239016
43178112	43178135	8	+	26627737	HCT116	viability after 18 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.5764871206418805	[595]	[229,200,145]	-5	hSpCas9	negative selection	2239017
43182237	43182260	8	-	26627737	HCT116	viability after 18 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.3806248049094283	[152]	[58,144,80]	3	hSpCas9	negative selection	2239018
43191582	43191605	8	-	26627737	HCT116	viability after 18 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.29295873614260354	[183]	[85,117,122]	2	hSpCas9	negative selection	2239019
43168199	43168222	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACCGCGCCCAGCCTGG	HGSNAT	ENSG00000165102	-0.6476236116882323	[118,215]	[30,13]	-3	dCas9-VP64	positive selection	2438099
43168199	43168222	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACCGCGCCCAGCCTGG	HGSNAT	ENSG00000165102	-0.5349507089340686	[327,308]	[84,58]	-5	dCas9-VP64	positive selection	2533354
43178112	43178135	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	0.5978550908015479	[2,3]	[3,4]	9	hSpCas9	positive selection	2993179
43170611	43170634	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.09803958284027928	[3,3]	[3,1]	-1	hSpCas9	positive selection	2993180
43170623	43170646	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.2255928819469958	[3,3]	[4,3]	5	hSpCas9	positive selection	2993181
43158601	43158624	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	0.412463822588634	[3,3]	[2,6]	8	hSpCas9	positive selection	2993182
43178112	43178135	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	0.24062613988062415	[2,2]	[2,2]	4	hSpCas9	positive selection	3061037
43170611	43170634	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.13507128088674092	[3,3]	[3,0]	-2	hSpCas9	positive selection	3061038
43170623	43170646	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.2778153949982856	[3,3]	[3,0]	-4	hSpCas9	positive selection	3061039
43158601	43158624	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	0.021994678901254144	[3,3]	[2,2]	0	hSpCas9	positive selection	3061040
43169205	43169228		-	24336571	A375	resistance to PLX after 7 days	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.1511489207713027	[7,6]	[5,6]	-5	hSpCas9	positive selection	3118948
43169230	43169253		-	24336571	A375	resistance to PLX after 7 days	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	-0.03283528545733705	[3,4]	[4,3]	-1	hSpCas9	positive selection	3118949
43161440	43161463		+	24336571	A375	resistance to PLX after 7 days	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.15145007522410803	[20,26]	[26,25]	5	hSpCas9	positive selection	3118950
43169205	43169228		-	24336571	A375	resistance to PLX after 14 days	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.42317167623483254	[5,5]	[3,3]	4	hSpCas9	positive selection	3176741
43169230	43169253		-	24336571	A375	resistance to PLX after 14 days	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	1.2945410908857609	[2,6]	[4,5]	8	hSpCas9	positive selection	3176742
43161440	43161463		+	24336571	A375	resistance to PLX after 14 days	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.3562985557696149	[22,24]	[6,9]	-4	hSpCas9	positive selection	3176743
43169205	43169228		-	24336571	A375	viability after 7 days	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.15597318394624293	[8]	[7,6]	-2	hSpCas9	negative selection	3234534
43169230	43169253		-	24336571	A375	viability after 7 days	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	-0.8430346360737063	[8]	[3,4]	-8	hSpCas9	negative selection	3234535
43161440	43161463		+	24336571	A375	viability after 7 days	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.8249996909232018	[13]	[20,26]	9	hSpCas9	negative selection	3234536
43169205	43169228		-	24336571	A375	viability after 14 days	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.32921695756912106	[8]	[5,5]	-4	hSpCas9	negative selection	3292327
43169230	43169253		-	24336571	A375	viability after 14 days	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	-0.7202730847689823	[8]	[2,6]	-7	hSpCas9	negative selection	3292328
43161440	43161463		+	24336571	A375	viability after 14 days	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.8387350570013141	[13]	[22,24]	9	hSpCas9	negative selection	3292329
43170598	43170621	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	1.019233737016867	[145,155]	[0,2]	4	hSpCas9	positive selection	3353338
43170622	43170645	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.666678012506675	[77,114]	[0,0]	3	hSpCas9	positive selection	3353339
43161440	43161463	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	2.0288847454365824	[35,38]	[0,0]	7	hSpCas9	positive selection	3353340
43169205	43169228	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	4.613470021671111	[74,74]	[11,11]	9	hSpCas9	positive selection	3372533
43169172	43169195	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	4.762561519696257	[61,61]	[10,10]	9	hSpCas9	positive selection	3372534
43161454	43161477	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.9719239925835867	[77,77]	[0,0]	4	hSpCas9	positive selection	3372535
43178111	43178134	8	+	26780180	HT29	viability (Avana library 4 designs)	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	1.15248168441721	[]	[]	4	hSpCas9	negative selection	3430440
43170611	43170634	8	-	26780180	HT29	viability (Avana library 4 designs)	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.130307697459646	[]	[]	-2	hSpCas9	negative selection	3430441
43170622	43170645	8	+	26780180	HT29	viability (Avana library 4 designs)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.24216748488822	[]	[]	0	hSpCas9	negative selection	3430442
43158600	43158623	8	+	26780180	HT29	viability (Avana library 4 designs)	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	0.407141025712211	[]	[]	1	hSpCas9	negative selection	3430443
43158600	43158623	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	1.22765566977044	[]	[]	1	hSpCas9	negative selection	3515602
43170611	43170634	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-2.99337509819652	[]	[]	-4	hSpCas9	negative selection	3515603
43170622	43170645	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	3.16357573580581	[]	[]	5	hSpCas9	negative selection	3515604
43178111	43178134	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	-4.01247466881335	[]	[]	-4	hSpCas9	negative selection	3515605
43140522	43140545	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACGCGGCCAGCAGCAGCGCGG	HGSNAT	ENSG00000165102	1.8657028469378	[]	[]	2	hSpCas9	negative selection	3515606
43147032	43147055	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATTCAGATTTCCAGTAGACGG	HGSNAT	ENSG00000165102	-0.527491498263592	[]	[]	0	hSpCas9	negative selection	3515607
43158600	43158623	8	+	26780180	A375	viability (Avana lentiGuide)	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	-5.83241583973454	[]	[]	-8	hSpCas9	negative selection	3624261
43170611	43170634	8	-	26780180	A375	viability (Avana lentiGuide)	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.117266286186746	[]	[]	0	hSpCas9	negative selection	3624262
43170622	43170645	8	+	26780180	A375	viability (Avana lentiGuide)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.110327542304356	[]	[]	0	hSpCas9	negative selection	3624263
43178111	43178134	8	+	26780180	A375	viability (Avana lentiGuide)	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	1.02668379055562	[]	[]	1	hSpCas9	negative selection	3624264
43140522	43140545	8	-	26780180	A375	viability (Avana lentiGuide)	GGACGCGGCCAGCAGCAGCGCGG	HGSNAT	ENSG00000165102	1.05261375015508	[]	[]	1	hSpCas9	negative selection	3624265
43147032	43147055	8	-	26780180	A375	viability (Avana lentiGuide)	GCATTCAGATTTCCAGTAGACGG	HGSNAT	ENSG00000165102	-3.28908900295622	[]	[]	-6	hSpCas9	negative selection	3624266
43158600	43158623	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	-0.01019030571729615	[5]	[5,4]	0	hSpCas9	positive selection	3732920
43170611	43170634	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.5936327308327977	[4]	[3,1]	-7	hSpCas9	positive selection	3732921
43170622	43170645	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.12284058165181078	[5]	[6,4]	3	hSpCas9	positive selection	3732922
43178111	43178134	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	-0.0979214309026904	[5]	[4,5]	-2	hSpCas9	positive selection	3732923
43140522	43140545	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACGCGGCCAGCAGCAGCGCGG	HGSNAT	ENSG00000165102	0.2883783813630796	[3]	[4,4]	8	hSpCas9	positive selection	3732924
43147032	43147055	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATTCAGATTTCCAGTAGACGG	HGSNAT	ENSG00000165102	-0.06896764231041098	[5]	[5,4]	-1	hSpCas9	positive selection	3732925
43158600	43158623	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCTCAGAGTCCAAAAGCAGGG	HGSNAT	ENSG00000165102	0.20941536945000208	[5]	[6,4]	5	hSpCas9	positive selection	3841527
43170611	43170634	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.048887798601041185	[5]	[4,3]	0	hSpCas9	positive selection	3841528
43170622	43170645	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.2827418325403892	[5]	[6,5]	7	hSpCas9	positive selection	3841529
43178111	43178134	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGACTTCTATACTGCAACGGGG	HGSNAT	ENSG00000165102	0.14148068133443198	[4]	[3,4]	3	hSpCas9	positive selection	3841530
43140522	43140545	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACGCGGCCAGCAGCAGCGCGG	HGSNAT	ENSG00000165102	-0.15096903781164195	[4]	[3,2]	-2	hSpCas9	positive selection	3841531
43147032	43147055	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATTCAGATTTCCAGTAGACGG	HGSNAT	ENSG00000165102	0.3766098358730784	[5]	[6,5]	9	hSpCas9	positive selection	3841532
43169205	43169228	8	-	26780180	A375	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.860654719917155	[]	[]	3	hSpCas9	negative selection	3947595
43170598	43170621	8	-	26780180	A375	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	1.08765869960401	[]	[]	5	hSpCas9	negative selection	3947596
43161440	43161463	8	+	26780180	A375	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.365652448713703	[]	[]	0	hSpCas9	negative selection	3947597
43170622	43170645	8	+	26780180	A375	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	1.31997670802342	[]	[]	7	hSpCas9	negative selection	3947598
43169172	43169195	8	+	26780180	A375	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.208234675250383	[]	[]	0	hSpCas9	negative selection	3947599
43161454	43161477	8	-	26780180	A375	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	1.33050078057731	[]	[]	7	hSpCas9	negative selection	3947600
43169205	43169228	8	-	26780180	HT29	viability (GeCKOv2 library)	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.746597831720869	[]	[]	3	hSpCas9	negative selection	4055561
43170598	43170621	8	-	26780180	HT29	viability (GeCKOv2 library)	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	2.31621958617655	[]	[]	9	hSpCas9	negative selection	4055562
43161440	43161463	8	+	26780180	HT29	viability (GeCKOv2 library)	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.590125537610061	[]	[]	2	hSpCas9	negative selection	4055563
43170622	43170645	8	+	26780180	HT29	viability (GeCKOv2 library)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.274479160479427	[]	[]	0	hSpCas9	negative selection	4055564
43169172	43169195	8	+	26780180	HT29	viability (GeCKOv2 library)	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.327040091073043	[]	[]	0	hSpCas9	negative selection	4055565
43161454	43161477	8	-	26780180	HT29	viability (GeCKOv2 library)	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	1.32047035645246	[]	[]	6	hSpCas9	negative selection	4055566
43169205	43169228	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.1289778451865491	[2]	[1,1]	3	hSpCas9	positive selection	4142415
43169230	43169253	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	0.3433009596204075	[1]	[0,2]	7	hSpCas9	positive selection	4142416
43161440	43161463	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.19544664792593905	[4]	[3,2]	5	hSpCas9	positive selection	4142417
43169205	43169228	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.6519927229164301	[2]	[2,3,0,0]	4	hSpCas9	positive selection	4206437
43169230	43169253	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATAACTTACAGAATTGATGAGG	HGSNAT	ENSG00000165102	0.09520690239920637	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4206438
43161440	43161463	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.31677201118149145	[4]	[1,3,0,0]	-5	hSpCas9	positive selection	4206439
43170598	43170621	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	-0.381791091145944	[3]	[2,1]	-7	hSpCas9	positive selection	4274928
43170622	43170645	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	1.0023965640756816	[2]	[3,6]	9	hSpCas9	positive selection	4274929
43161440	43161463	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.4724039654843837	[1]	[1,1]	8	hSpCas9	positive selection	4274930
43169205	43169228	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.4169436253243314	[2]	[2,2]	8	hSpCas9	positive selection	4339189
43169172	43169195	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	-0.267488506240119	[1]	[1,0]	-5	hSpCas9	positive selection	4339190
43161454	43161477	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.3452739053018029	[2]	[2,0]	-6	hSpCas9	positive selection	4339191
43158655	43158677	8	-	27760321	OCIAML3	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.4185766154919244	[722,570]	[373,378]	-4	hSpCas9	negative selection	4406806
43159026	43159048	8	-	27760321	OCIAML3	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-2.6661987327811216	[13,19]	[2,0]	-9	hSpCas9	negative selection	4406807
43170623	43170645	8	+	27760321	OCIAML3	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.07586306027368124	[545,440]	[348,383]	-1	hSpCas9	negative selection	4406808
43173729	43173751	8	-	27760321	OCIAML3	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	-0.18951392640005815	[560,427]	[352,314]	-2	hSpCas9	negative selection	4406809
43178113	43178135	8	+	27760321	OCIAML3	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.7764557491201403	[605,559]	[171,388]	-6	hSpCas9	negative selection	4406810
43158655	43158677	8	-	27760321	OCIAML2	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.021127440017149945	[722,570]	[458,582]	0	hSpCas9	negative selection	4490269
43159026	43159048	8	-	27760321	OCIAML2	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-3.80701968294455	[13,19]	[0,0]	-9	hSpCas9	negative selection	4490270
43170623	43170645	8	+	27760321	OCIAML2	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.3824133427433438	[545,440]	[435,624]	5	hSpCas9	negative selection	4490271
43173729	43173751	8	-	27760321	OCIAML2	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	-0.6079340991969753	[560,427]	[237,289]	-6	hSpCas9	negative selection	4490272
43178113	43178135	8	+	27760321	OCIAML2	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.028952007979485384	[605,559]	[450,520]	0	hSpCas9	negative selection	4490273
43158655	43158677	8	-	27760321	MV411	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.9019623980727787	[722,570]	[719,901]	6	hSpCas9	negative selection	4573732
43159026	43159048	8	-	27760321	MV411	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	1.9119000880787573	[13,19]	[0,105]	9	hSpCas9	negative selection	4573733
43170623	43170645	8	+	27760321	MV411	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	1.0926561650254354	[545,440]	[619,796]	7	hSpCas9	negative selection	4573734
43173729	43173751	8	-	27760321	MV411	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	-0.35940715063258366	[560,427]	[239,270]	-3	hSpCas9	negative selection	4573735
43178113	43178135	8	+	27760321	MV411	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.5792967234826045	[605,559]	[139,433]	-4	hSpCas9	negative selection	4573736
43158655	43158677	8	-	27760321	HL60	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.41925503119140806	[722,570]	[399,384]	-5	hSpCas9	negative selection	4657195
43159026	43159048	8	-	27760321	HL60	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-3.821065910558956	[13,19]	[0,0]	-9	hSpCas9	negative selection	4657196
43170623	43170645	8	+	27760321	HL60	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.5177123000021088	[545,440]	[507,643]	6	hSpCas9	negative selection	4657197
43173729	43173751	8	-	27760321	HL60	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.02708788809919002	[560,427]	[421,393]	0	hSpCas9	negative selection	4657198
43178113	43178135	8	+	27760321	HL60	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.37409934784235754	[605,559]	[432,297]	-4	hSpCas9	negative selection	4657199
43158655	43158677	8	-	27760321	HT1080	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.7627664237268186	[570,445]	[337,349]	4	hSpCas9	negative selection	4740658
43159026	43159048	8	-	27760321	HT1080	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-2.844317238920959	[19,15]	[0,0]	-7	hSpCas9	negative selection	4740659
43170623	43170645	8	+	27760321	HT1080	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.4991958823574853	[440,343]	[241,197]	2	hSpCas9	negative selection	4740660
43173729	43173751	8	-	27760321	HT1080	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.6330481366331936	[427,333]	[253,214]	3	hSpCas9	negative selection	4740661
43178113	43178135	8	+	27760321	HT1080	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.055454911529281836	[559,436]	[150,234]	0	hSpCas9	negative selection	4740662
43158655	43158677	8	-	27760321	HT29	viability after 7 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.20001059781064356	[570,445]	[920,817,543]	3	hSpCas9	negative selection	4824121
43159026	43159048	8	-	27760321	HT29	viability after 7 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	0.08687594209679439	[19,15]	[23,1,46]	1	hSpCas9	negative selection	4824122
43170623	43170645	8	+	27760321	HT29	viability after 7 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.041430504208599575	[440,343]	[503,437,528]	0	hSpCas9	negative selection	4824123
43173729	43173751	8	-	27760321	HT29	viability after 7 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.1287523713529356	[427,333]	[532,390,676]	2	hSpCas9	negative selection	4824124
43178113	43178135	8	+	27760321	HT29	viability after 7 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.10877362875781454	[559,436]	[694,721,656]	1	hSpCas9	negative selection	4824125
43158655	43158677	8	-	27760321	HT29	viability after 25 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.4278500718152821	[570,445]	[620,798,951]	4	hSpCas9	negative selection	4907584
43159026	43159048	8	-	27760321	HT29	viability after 25 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-3.9823728298690053	[19,15]	[0,0,1]	-9	hSpCas9	negative selection	4907585
43170623	43170645	8	+	27760321	HT29	viability after 25 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.276057728274052	[440,343]	[615,593,398]	3	hSpCas9	negative selection	4907586
43173729	43173751	8	-	27760321	HT29	viability after 25 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.48460030688307454	[427,333]	[613,589,623]	5	hSpCas9	negative selection	4907587
43178113	43178135	8	+	27760321	HT29	viability after 25 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.003616149377011879	[559,436]	[427,588,719]	0	hSpCas9	negative selection	4907588
43158655	43158677	8	-	27760321	HT29	viability after 22 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.1679911486642358	[570,445]	[701,647,629]	1	hSpCas9	negative selection	4991047
43159026	43159048	8	-	27760321	HT29	viability after 22 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-1.8753672608153238	[19,15]	[7,0,7]	-8	hSpCas9	negative selection	4991048
43170623	43170645	8	+	27760321	HT29	viability after 22 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.19288308223612982	[440,343]	[288,586,316]	-2	hSpCas9	negative selection	4991049
43173729	43173751	8	-	27760321	HT29	viability after 22 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.2891009385034096	[427,333]	[345,495,779]	3	hSpCas9	negative selection	4991050
43178113	43178135	8	+	27760321	HT29	viability after 22 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.1400112526075183	[559,436]	[462,642,463]	-1	hSpCas9	negative selection	4991051
43158655	43158677	8	-	27760321	HT29	viability after 19 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.3970769255388933	[570,445]	[766,464,1053]	4	hSpCas9	negative selection	5074510
43159026	43159048	8	-	27760321	HT29	viability after 19 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-1.0654674804210522	[19,15]	[29,0,0]	-6	hSpCas9	negative selection	5074511
43170623	43170645	8	+	27760321	HT29	viability after 19 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.2535805810482136	[440,343]	[609,470,531]	2	hSpCas9	negative selection	5074512
43173729	43173751	8	-	27760321	HT29	viability after 19 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.37364066254020767	[427,333]	[896,505,333]	3	hSpCas9	negative selection	5074513
43178113	43178135	8	+	27760321	HT29	viability after 19 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.1109398660015391	[559,436]	[540,655,392]	-1	hSpCas9	negative selection	5074514
43158655	43158677	8	-	27760321	HT29	viability after 16 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.496230864781657	[570,445]	[728,780,890]	5	hSpCas9	negative selection	5157973
43159026	43159048	8	-	27760321	HT29	viability after 16 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-4.334013630782607	[19,15]	[0,0,0]	-9	hSpCas9	negative selection	5157974
43170623	43170645	8	+	27760321	HT29	viability after 16 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.6330521664890023	[440,343]	[958,571,540]	7	hSpCas9	negative selection	5157975
43173729	43173751	8	-	27760321	HT29	viability after 16 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.24136957677811183	[427,333]	[572,584,357]	2	hSpCas9	negative selection	5157976
43178113	43178135	8	+	27760321	HT29	viability after 16 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.023822859072945513	[559,436]	[548,613,480]	0	hSpCas9	negative selection	5157977
43158655	43158677	8	-	27760321	HT29	viability after 13 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.5116604180311313	[570,445]	[860,990,680]	6	hSpCas9	negative selection	5241436
43159026	43159048	8	-	27760321	HT29	viability after 13 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-0.21898973950162315	[19,15]	[0,52,0]	-3	hSpCas9	negative selection	5241437
43170623	43170645	8	+	27760321	HT29	viability after 13 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.5457113816148866	[440,343]	[555,907,537]	7	hSpCas9	negative selection	5241438
43173729	43173751	8	-	27760321	HT29	viability after 13 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.20159958256327914	[427,333]	[666,529,337]	2	hSpCas9	negative selection	5241439
43178113	43178135	8	+	27760321	HT29	viability after 13 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.21412512689154029	[559,436]	[285,710,498]	-3	hSpCas9	negative selection	5241440
43158655	43158677	8	-	27760321	HT29	viability after 10 days	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.11795002871351679	[570,445]	[625,818,626]	1	hSpCas9	negative selection	5324899
43159026	43159048	8	-	27760321	HT29	viability after 10 days	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-4.492312337387089	[19,15]	[0,0,0]	-9	hSpCas9	negative selection	5324900
43170623	43170645	8	+	27760321	HT29	viability after 10 days	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.2170990876533574	[440,343]	[784,537,388]	3	hSpCas9	negative selection	5324901
43173729	43173751	8	-	27760321	HT29	viability after 10 days	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	0.007065656792358904	[427,333]	[373,403,649]	0	hSpCas9	negative selection	5324902
43178113	43178135	8	+	27760321	HT29	viability after 10 days	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.20082327127643296	[559,436]	[588,610,428]	-3	hSpCas9	negative selection	5324903
43158655	43158677	8	-	27760321	MOLM13	viability	CTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.5226389559134856	[722,570]	[768,309]	3	hSpCas9	negative selection	5408362
43159026	43159048	8	-	27760321	MOLM13	viability	TACGAAGGTTACTATCAACTGG	HGSNAT	ENSG00000165102	-1.3993005123745919	[13,19]	[0,5]	-7	hSpCas9	negative selection	5408363
43170623	43170645	8	+	27760321	MOLM13	viability	TGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.08691523721742724	[545,440]	[250,268]	0	hSpCas9	negative selection	5408364
43173729	43173751	8	-	27760321	MOLM13	viability	AACTCACCACGGGAACACGAGG	HGSNAT	ENSG00000165102	-0.024938919465989	[560,427]	[317,232]	0	hSpCas9	negative selection	5408365
43178113	43178135	8	+	27760321	MOLM13	viability	GACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.583790747473363	[605,559]	[660,349]	4	hSpCas9	negative selection	5408366
43140482	43140505	8	+	27661255	K562	viability	GAGCGGGCGGCGGGCATGAGCGG	HGSNAT	ENSG00000165102	0.002565863489808917	[452,379]	[322,343]	0	dCas9-KRAB	negative selection	5484567
43140761	43140784	8	+	27661255	K562	viability	GGTCCCGCGCCCCAGACCGGAGG	HGSNAT	ENSG00000165102	-0.21715825361720772	[707,815]	[558,490]	-6	dCas9-KRAB	negative selection	5484568
43140902	43140925	8	+	27661255	K562	viability	GGCGCCTTCCGTCTAAACAGAGG	HGSNAT	ENSG00000165102	-0.03100495786127344	[511,499]	[425,369]	-1	dCas9-KRAB	negative selection	5484569
43140936	43140959	8	+	27661255	K562	viability	GACGCCGGGACCCCACAAACTGG	HGSNAT	ENSG00000165102	-0.18679037487909486	[862,860]	[618,592]	-5	dCas9-KRAB	negative selection	5484570
43140681	43140704	8	-	27661255	K562	viability	GGCGCCGCGCACGGAGATAGGGG	HGSNAT	ENSG00000165102	0.04745953361570903	[825,598]	[671,522]	1	dCas9-KRAB	negative selection	5484571
43140784	43140807	8	-	27661255	K562	viability	GGCCGCAGCACCCCGAAGTCCGG	HGSNAT	ENSG00000165102	0.1265399530552168	[697,887]	[748,636]	4	dCas9-KRAB	negative selection	5484572
43140925	43140948	8	-	27661255	K562	viability	GGTCCCGGCGTCCCGATCCGCGG	HGSNAT	ENSG00000165102	-0.10452378992256398	[881,991]	[752,644]	-4	dCas9-KRAB	negative selection	5484573
43170598	43170621	8	-	27260156	BXPC3	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.19014777362532387	[669]	[835,713,909,724]	4	hSpCas9	negative selection	5547388
43170622	43170645	8	+	27260156	BXPC3	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.3199198984769947	[411]	[423,565,429,763]	7	hSpCas9	negative selection	5547389
43161440	43161463	8	+	27260156	BXPC3	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.0711858667445795	[84]	[89,121,56,102]	1	hSpCas9	negative selection	5547390
43169205	43169228	8	-	27260156	BXPC3	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.05437854790921137	[226]	[199,144,249,339]	-1	hSpCas9	negative selection	5611649
43169172	43169195	8	+	27260156	BXPC3	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.5514341776319887	[127]	[180,157,187,268]	9	hSpCas9	negative selection	5611650
43161454	43161477	8	-	27260156	BXPC3	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.4815061997407891	[419]	[291,300,292,380]	-8	hSpCas9	negative selection	5611651
43170598	43170621	8	-	27260156	A673	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.1662227231548935	[669]	[1031,824,886,880]	4	hSpCas9	negative selection	5668639
43170622	43170645	8	+	27260156	A673	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.06665989217090379	[411]	[549,467,453,422]	-2	hSpCas9	negative selection	5668640
43161440	43161463	8	+	27260156	A673	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.2757907334091012	[84]	[110,135,168,72]	6	hSpCas9	negative selection	5668641
43169205	43169228	8	-	27260156	A673	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.02478980293185895	[226]	[270,300,278,254]	0	hSpCas9	negative selection	5732900
43169172	43169195	8	+	27260156	A673	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.3449945888949546	[127]	[194,158,217,209]	7	hSpCas9	negative selection	5732901
43161454	43161477	8	-	27260156	A673	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.3038172370653549	[419]	[513,319,344,472]	-6	hSpCas9	negative selection	5732902
43170598	43170621	8	-	27260156	A375	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.1216762108042092	[669]	[886,974,846,725]	1	hSpCas9	negative selection	5789890
43170622	43170645	8	+	27260156	A375	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.32532571167594304	[411]	[591,873,562,437]	5	hSpCas9	negative selection	5789891
43161440	43161463	8	+	27260156	A375	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.825142509249077	[84]	[194,195,195,124]	9	hSpCas9	negative selection	5789892
43169205	43169228	8	-	27260156	A375	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5363290742015968	[226]	[384,406,365,381]	7	hSpCas9	negative selection	5854151
43169172	43169195	8	+	27260156	A375	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.8398919143074044	[127]	[314,438,177,172]	9	hSpCas9	negative selection	5854152
43161454	43161477	8	-	27260156	A375	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.19858403062715585	[419]	[690,525,738,318]	3	hSpCas9	negative selection	5854153
43170598	43170621	8	-	27260156	COLO741	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.12433801821133605	[669]	[1151,794,872]	2	hSpCas9	negative selection	5911141
43170622	43170645	8	+	27260156	COLO741	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.10875874281899577	[411]	[550,605,544]	2	hSpCas9	negative selection	5911142
43161440	43161463	8	+	27260156	COLO741	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	1.0661103174361315	[84]	[222,142,308]	9	hSpCas9	negative selection	5911143
43169205	43169228	8	-	27260156	COLO741	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.14611175093250606	[226]	[380,207,373]	3	hSpCas9	negative selection	5975402
43169172	43169195	8	+	27260156	COLO741	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.25121997574093724	[127]	[223,153,206]	5	hSpCas9	negative selection	5975403
43161454	43161477	8	-	27260156	COLO741	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.20927272964476126	[419]	[550,415,433]	-4	hSpCas9	negative selection	5975404
43170598	43170621	8	-	27260156	CAL120	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	-0.15593036704281937	[669]	[674,718,837]	-2	hSpCas9	negative selection	6032392
43170622	43170645	8	+	27260156	CAL120	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.0015723596979093368	[411]	[264,330,895]	0	hSpCas9	negative selection	6032393
43161440	43161463	8	+	27260156	CAL120	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.17903255681748842	[84]	[61,146,66]	-3	hSpCas9	negative selection	6032394
43169205	43169228	8	-	27260156	CAL120	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.24101126081021984	[226]	[364,303,336]	3	hSpCas9	negative selection	6096653
43169172	43169195	8	+	27260156	CAL120	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.6167955005081864	[127]	[391,124,237]	8	hSpCas9	negative selection	6096654
43161454	43161477	8	-	27260156	CAL120	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.3913742953899688	[419]	[302,486,390]	-5	hSpCas9	negative selection	6096655
43170598	43170621	8	-	27260156	CADOES1	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.14620524017995473	[669]	[588,817,634,717]	2	hSpCas9	negative selection	6153643
43170622	43170645	8	+	27260156	CADOES1	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.15609192720484472	[411]	[388,341,311,331]	-3	hSpCas9	negative selection	6153644
43161440	43161463	8	+	27260156	CADOES1	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.38310297079389555	[84]	[134,70,83,122]	6	hSpCas9	negative selection	6153645
43169205	43169228	8	-	27260156	CADOES1	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.24197736440500905	[226]	[345,198,263,186]	4	hSpCas9	negative selection	6217904
43169172	43169195	8	+	27260156	CADOES1	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.6376571245102782	[127]	[124,180,172,264]	9	hSpCas9	negative selection	6217905
43161454	43161477	8	-	27260156	CADOES1	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.1416943471822846	[419]	[440,289,304,380]	-2	hSpCas9	negative selection	6217906
43170598	43170621	8	-	27260156	EWS502	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.06219199461717262	[669]	[857,686,639,763]	1	hSpCas9	negative selection	6274894
43170622	43170645	8	+	27260156	EWS502	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.20192197348068341	[411]	[470,308,305,423]	-4	hSpCas9	negative selection	6274895
43161440	43161463	8	+	27260156	EWS502	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.9531219619971787	[84]	[163,191,165,174]	9	hSpCas9	negative selection	6274896
43169205	43169228	8	-	27260156	EWS502	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.795742034774906	[226]	[295,354,185,877]	9	hSpCas9	negative selection	6339155
43169172	43169195	8	+	27260156	EWS502	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.2846406155982961	[127]	[115,159,208,182]	5	hSpCas9	negative selection	6339156
43161454	43161477	8	-	27260156	EWS502	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.4179570453419855	[419]	[327,348,341,309]	-6	hSpCas9	negative selection	6339157
43170598	43170621	8	-	27260156	EW8	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.06841056153393799	[669]	[656,697,350,616]	1	hSpCas9	negative selection	6396145
43170622	43170645	8	+	27260156	EW8	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.034354761809777506	[411]	[321,364,369,302]	0	hSpCas9	negative selection	6396146
43161440	43161463	8	+	27260156	EW8	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.3242789470978651	[84]	[90,174,37,49]	6	hSpCas9	negative selection	6396147
43169205	43169228	8	-	27260156	EW8	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.49662083961825265	[226]	[233,344,212,250]	8	hSpCas9	negative selection	6460406
43169172	43169195	8	+	27260156	EW8	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.8123230172188707	[127]	[148,282,188,102]	9	hSpCas9	negative selection	6460407
43161454	43161477	8	-	27260156	EW8	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.15224400507054311	[419]	[330,402,232,272]	-3	hSpCas9	negative selection	6460408
43170598	43170621	8	-	27260156	CORL105	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.2776374036145387	[669]	[810,989,1088,928]	5	hSpCas9	negative selection	6517396
43170622	43170645	8	+	27260156	CORL105	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.02888302447969504	[411]	[350,530,603,493]	0	hSpCas9	negative selection	6517397
43161440	43161463	8	+	27260156	CORL105	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.7171881722591675	[84]	[153,144,180,176]	9	hSpCas9	negative selection	6517398
43169205	43169228	8	-	27260156	CORL105	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.11058353478336835	[226]	[351,314,257,219]	2	hSpCas9	negative selection	6581657
43169172	43169195	8	+	27260156	CORL105	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.22937280059949772	[127]	[218,217,152,109]	4	hSpCas9	negative selection	6581658
43161454	43161477	8	-	27260156	CORL105	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.40391744690126674	[419]	[416,380,446,254]	-6	hSpCas9	negative selection	6581659
43170598	43170621	8	-	27260156	HS294T	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.2904233766402714	[669]	[278,300,285,421]	4	hSpCas9	negative selection	6638647
43170622	43170645	8	+	27260156	HS294T	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.17972628405895932	[411]	[179,192,150,199]	2	hSpCas9	negative selection	6638648
43161440	43161463	8	+	27260156	HS294T	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.583423314728913	[84]	[28,41,88,36]	7	hSpCas9	negative selection	6638649
43169205	43169228	8	-	27260156	HS294T	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.04827549149409327	[226]	[59,136,91,71]	0	hSpCas9	negative selection	6702908
43169172	43169195	8	+	27260156	HS294T	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	-0.15498905023001486	[127]	[63,29,38,42]	-2	hSpCas9	negative selection	6702909
43161454	43161477	8	-	27260156	HS294T	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.20312350619550842	[419]	[237,167,123,217]	2	hSpCas9	negative selection	6702910
43170598	43170621	8	-	27260156	HCC44	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.07006788623367033	[669]	[832,539,1080,809]	1	hSpCas9	negative selection	6759898
43170622	43170645	8	+	27260156	HCC44	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.2607917847233967	[411]	[834,357,651,456]	4	hSpCas9	negative selection	6759899
43161440	43161463	8	+	27260156	HCC44	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.16250132051872912	[84]	[110,63,144,121]	2	hSpCas9	negative selection	6759900
43169205	43169228	8	-	27260156	HCC44	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.026191782170184696	[226]	[277,300,248,210]	0	hSpCas9	negative selection	6824159
43169172	43169195	8	+	27260156	HCC44	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.37653947737642945	[127]	[179,334,123,81]	6	hSpCas9	negative selection	6824160
43161454	43161477	8	-	27260156	HCC44	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.0219777472605662	[419]	[442,345,635,485]	0	hSpCas9	negative selection	6824161
43170598	43170621	8	-	27260156	G402	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.36636723796826964	[669]	[1657,651,1073,898]	4	hSpCas9	negative selection	6881149
43170622	43170645	8	+	27260156	G402	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.016303353680245186	[411]	[786,596,435,268]	0	hSpCas9	negative selection	6881150
43161440	43161463	8	+	27260156	G402	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.05508526734046626	[84]	[176,33,89,104]	0	hSpCas9	negative selection	6881151
43169205	43169228	8	-	27260156	G402	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.17447024248303378	[226]	[294,436,148,369]	2	hSpCas9	negative selection	6945410
43169172	43169195	8	+	27260156	G402	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.4828385745746657	[127]	[142,198,294,222]	6	hSpCas9	negative selection	6945411
43161454	43161477	8	-	27260156	G402	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.39031840208449264	[419]	[275,301,619,344]	-5	hSpCas9	negative selection	6945412
43170598	43170621	8	-	27260156	L33	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.14905890225359864	[669]	[717,286,461,817]	3	hSpCas9	negative selection	7002400
43170622	43170645	8	+	27260156	L33	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.13785019221365502	[411]	[517,179,267,427]	3	hSpCas9	negative selection	7002401
43161440	43161463	8	+	27260156	L33	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.09607194567443944	[84]	[70,32,51,83]	-2	hSpCas9	negative selection	7002402
43169205	43169228	8	-	27260156	L33	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.01678985203587402	[226]	[257,69,160,232]	0	hSpCas9	negative selection	7066661
43169172	43169195	8	+	27260156	L33	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	-0.13075692150844365	[127]	[145,47,63,101]	-3	hSpCas9	negative selection	7066662
43161454	43161477	8	-	27260156	L33	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.5938514739250823	[419]	[281,122,205,203]	-8	hSpCas9	negative selection	7066663
43170598	43170621	8	-	27260156	K562	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.43477935694331904	[669]	[751,400,710,1266]	5	hSpCas9	negative selection	7123651
43170622	43170645	8	+	27260156	K562	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.4970757854638077	[411]	[429,718,593,342]	6	hSpCas9	negative selection	7123652
43161440	43161463	8	+	27260156	K562	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.7613722208313978	[84]	[269,50,45,148]	8	hSpCas9	negative selection	7123653
43169205	43169228	8	-	27260156	K562	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5739956791748582	[226]	[150,379,554,124]	7	hSpCas9	negative selection	7187912
43169172	43169195	8	+	27260156	K562	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.3182577237430393	[127]	[109,158,75,210]	4	hSpCas9	negative selection	7187913
43161454	43161477	8	-	27260156	K562	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-1.3007832665878711	[419]	[90,109,212,179]	-8	hSpCas9	negative selection	7187914
43170598	43170621	8	-	27260156	HT29	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.039090452564428446	[669]	[810,757,787,959]	0	hSpCas9	negative selection	7244902
43170622	43170645	8	+	27260156	HT29	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.1282776270589952	[411]	[538,428,368,491]	-3	hSpCas9	negative selection	7244903
43161440	43161463	8	+	27260156	HT29	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.38981729087948835	[84]	[112,216,99,117]	7	hSpCas9	negative selection	7244904
43169205	43169228	8	-	27260156	HT29	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.3626978481909201	[226]	[362,274,287,469]	7	hSpCas9	negative selection	7309163
43169172	43169195	8	+	27260156	HT29	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.3940200854985474	[127]	[271,160,172,210]	7	hSpCas9	negative selection	7309164
43161454	43161477	8	-	27260156	HT29	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.18946302889821073	[419]	[470,347,631,342]	-4	hSpCas9	negative selection	7309165
43170598	43170621	8	-	27260156	MHHES1	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.1285667685854205	[669]	[665,1041,1084,555]	2	hSpCas9	negative selection	7366153
43170622	43170645	8	+	27260156	MHHES1	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.44480937478727645	[411]	[529,286,364,219]	-7	hSpCas9	negative selection	7366154
43161440	43161463	8	+	27260156	MHHES1	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.31910770453276216	[84]	[121,239,117,28]	6	hSpCas9	negative selection	7366155
43169205	43169228	8	-	27260156	MHHES1	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.454680984532574	[226]	[431,294,393,290]	7	hSpCas9	negative selection	7430414
43169172	43169195	8	+	27260156	MHHES1	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.2471466778377278	[127]	[166,60,151,265]	4	hSpCas9	negative selection	7430415
43161454	43161477	8	-	27260156	MHHES1	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.0798548856501766	[419]	[351,401,673,526]	1	hSpCas9	negative selection	7430416
43170598	43170621	8	-	27260156	MEWO	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.0700927972771942	[669]	[892,549,576]	1	hSpCas9	negative selection	7487404
43170622	43170645	8	+	27260156	MEWO	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.22111958197902137	[411]	[464,414,470]	5	hSpCas9	negative selection	7487405
43161440	43161463	8	+	27260156	MEWO	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.3070685654058236	[84]	[91,76,124]	6	hSpCas9	negative selection	7487406
43169205	43169228	8	-	27260156	MEWO	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.17324174097703426	[226]	[278,241,204]	4	hSpCas9	negative selection	7551665
43169172	43169195	8	+	27260156	MEWO	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.2626830723065223	[127]	[142,110,176]	5	hSpCas9	negative selection	7551666
43161454	43161477	8	-	27260156	MEWO	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.5857700464835472	[419]	[275,286,224]	-8	hSpCas9	negative selection	7551667
43170598	43170621	8	-	27260156	LNCAPCLONEFGC	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.19528296364957476	[669]	[733,575,834,661]	3	hSpCas9	negative selection	7608655
43170622	43170645	8	+	27260156	LNCAPCLONEFGC	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.22140735527793057	[411]	[214,504,597,445]	3	hSpCas9	negative selection	7608656
43161440	43161463	8	+	27260156	LNCAPCLONEFGC	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.7140003140724471	[84]	[100,97,122,184]	9	hSpCas9	negative selection	7608657
43169205	43169228	8	-	27260156	LNCAPCLONEFGC	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5519798038646843	[226]	[406,349,237,195]	8	hSpCas9	negative selection	7672916
43169172	43169195	8	+	27260156	LNCAPCLONEFGC	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.6983824509802947	[127]	[170,114,230,246]	9	hSpCas9	negative selection	7672917
43161454	43161477	8	-	27260156	LNCAPCLONEFGC	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.4223087896638513	[419]	[254,284,344,259]	-6	hSpCas9	negative selection	7672918
43170598	43170621	8	-	27260156	PANC0327	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.19597150304549305	[669]	[381,871,826,596]	3	hSpCas9	negative selection	7729906
43170622	43170645	8	+	27260156	PANC0327	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.017899040106956893	[411]	[501,234,221,550]	0	hSpCas9	negative selection	7729907
43161440	43161463	8	+	27260156	PANC0327	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.10612359603933674	[84]	[78,63,45,137]	1	hSpCas9	negative selection	7729908
43169205	43169228	8	-	27260156	PANC0327	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.2887621920411729	[226]	[182,362,230,187]	4	hSpCas9	negative selection	7794167
43169172	43169195	8	+	27260156	PANC0327	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	1.4154052848067582	[127]	[60,118,856,180]	9	hSpCas9	negative selection	7794168
43161454	43161477	8	-	27260156	PANC0327	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.1992894677296991	[419]	[435,269,349,259]	-3	hSpCas9	negative selection	7794169
43170598	43170621	8	-	27260156	NCIH2009	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.24498544876870731	[669]	[1226,966,1157]	3	hSpCas9	negative selection	7851157
43170622	43170645	8	+	27260156	NCIH2009	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.3591920997384249	[411]	[1125,487,680]	5	hSpCas9	negative selection	7851158
43161440	43161463	8	+	27260156	NCIH2009	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.11239932114974849	[84]	[189,78,128]	1	hSpCas9	negative selection	7851159
43169205	43169228	8	-	27260156	NCIH2009	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.4751786659436916	[226]	[418,415,482]	6	hSpCas9	negative selection	7915418
43169172	43169195	8	+	27260156	NCIH2009	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.8522666413517759	[127]	[367,209,400]	9	hSpCas9	negative selection	7915419
43161454	43161477	8	-	27260156	NCIH2009	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.14667005898942057	[419]	[617,679,305]	-2	hSpCas9	negative selection	7915420
43170598	43170621	8	-	27260156	NCIH1373	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.6519695953749739	[669]	[1899,955,1119,224]	6	hSpCas9	negative selection	7972408
43170622	43170645	8	+	27260156	NCIH1373	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.25290333812321275	[411]	[881,551,458,90]	2	hSpCas9	negative selection	7972409
43161440	43161463	8	+	27260156	NCIH1373	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.5511669799138137	[84]	[197,105,174,22]	5	hSpCas9	negative selection	7972410
43169205	43169228	8	-	27260156	NCIH1373	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.19635170050428852	[226]	[155,137,108,131]	-2	hSpCas9	negative selection	8036669
43169172	43169195	8	+	27260156	NCIH1373	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	1.154287082474192	[127]	[316,557,66,81]	9	hSpCas9	negative selection	8036670
43161454	43161477	8	-	27260156	NCIH1373	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.44415435467242603	[419]	[331,293,299,122]	-4	hSpCas9	negative selection	8036671
43170598	43170621	8	-	27260156	PATU8902	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.22730304022419257	[669]	[1402,840,1144,933]	2	hSpCas9	negative selection	8093659
43170622	43170645	8	+	27260156	PATU8902	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.1976541304837096	[411]	[561,978,618,454]	2	hSpCas9	negative selection	8093660
43161440	43161463	8	+	27260156	PATU8902	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.9276125522400822	[84]	[246,160,240,247]	8	hSpCas9	negative selection	8093661
43169205	43169228	8	-	27260156	PATU8902	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.7749514535046869	[226]	[277,539,428,999]	7	hSpCas9	negative selection	8157920
43169172	43169195	8	+	27260156	PATU8902	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	1.0796151311690974	[127]	[316,470,172,626]	9	hSpCas9	negative selection	8157921
43161454	43161477	8	-	27260156	PATU8902	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.23328219069652473	[419]	[472,622,682,1007]	2	hSpCas9	negative selection	8157922
43170598	43170621	8	-	27260156	PANC1	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	-0.06284642178457917	[669]	[605,683,601,360]	-1	hSpCas9	negative selection	8214910
43170622	43170645	8	+	27260156	PANC1	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.08931866162401249	[411]	[358,499,291,373]	1	hSpCas9	negative selection	8214911
43161440	43161463	8	+	27260156	PANC1	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.6853069484253764	[84]	[121,220,99,55]	9	hSpCas9	negative selection	8214912
43169205	43169228	8	-	27260156	PANC1	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5340356163381887	[226]	[268,351,309,218]	8	hSpCas9	negative selection	8279171
43169172	43169195	8	+	27260156	PANC1	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.07280597015449208	[127]	[135,163,122,56]	1	hSpCas9	negative selection	8279172
43161454	43161477	8	-	27260156	PANC1	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.09974621437754863	[419]	[256,676,252,240]	-2	hSpCas9	negative selection	8279173
43170598	43170621	8	-	27260156	PANC0813	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	-0.15553036143643667	[669]	[724,624,749,725]	-3	hSpCas9	negative selection	8336161
43170622	43170645	8	+	27260156	PANC0813	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.047334353139171836	[411]	[535,421,559,485]	0	hSpCas9	negative selection	8336162
43161440	43161463	8	+	27260156	PANC0813	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.48761616542092523	[84]	[172,135,84,166]	7	hSpCas9	negative selection	8336163
43169205	43169228	8	-	27260156	PANC0813	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.464636075048637	[226]	[225,553,331,346]	7	hSpCas9	negative selection	8400422
43169172	43169195	8	+	27260156	PANC0813	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.7503990597206676	[127]	[302,229,283,201]	9	hSpCas9	negative selection	8400423
43161454	43161477	8	-	27260156	PANC0813	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.575426596218278	[419]	[266,348,318,379]	-7	hSpCas9	negative selection	8400424
43170598	43170621	8	-	27260156	RDES	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.17981617561877783	[669]	[658,808,948,1145]	3	hSpCas9	negative selection	8457412
43170622	43170645	8	+	27260156	RDES	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.20487675817230216	[411]	[397,336,548,352]	-3	hSpCas9	negative selection	8457413
43161440	43161463	8	+	27260156	RDES	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.7542153695134879	[84]	[175,144,190,137]	9	hSpCas9	negative selection	8457414
43169205	43169228	8	-	27260156	RDES	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5425035191255199	[226]	[346,305,431,450]	8	hSpCas9	negative selection	8521673
43169172	43169195	8	+	27260156	RDES	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.7869668294685166	[127]	[243,230,246,295]	9	hSpCas9	negative selection	8521674
43161454	43161477	8	-	27260156	RDES	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.048389348357207804	[419]	[344,581,526,565]	0	hSpCas9	negative selection	8521675
43170598	43170621	8	-	27260156	PC3	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.2500945014183137	[669]	[602,802,1157,742]	5	hSpCas9	negative selection	8578663
43170622	43170645	8	+	27260156	PC3	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.026936141460365215	[411]	[355,363,681,282]	0	hSpCas9	negative selection	8578664
43161440	43161463	8	+	27260156	PC3	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	-0.02571668610373834	[84]	[61,80,80,108]	0	hSpCas9	negative selection	8578665
43169205	43169228	8	-	27260156	PC3	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.10604236259588895	[226]	[117,271,490,222]	2	hSpCas9	negative selection	8642924
43169172	43169195	8	+	27260156	PC3	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.2517960781489117	[127]	[84,140,257,182]	5	hSpCas9	negative selection	8642925
43161454	43161477	8	-	27260156	PC3	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.7334405774836991	[419]	[185,206,448,244]	-9	hSpCas9	negative selection	8642926
43170598	43170621	8	-	27260156	PATU8988T	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.03156588739603916	[669]	[390,995,693,590]	0	hSpCas9	negative selection	8699914
43170622	43170645	8	+	27260156	PATU8988T	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.3788820115039586	[411]	[426,689,478,488]	6	hSpCas9	negative selection	8699915
43161440	43161463	8	+	27260156	PATU8988T	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.5632459945255501	[84]	[56,100,196,127]	8	hSpCas9	negative selection	8699916
43169205	43169228	8	-	27260156	PATU8988T	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.21204254871554173	[226]	[174,295,329,214]	3	hSpCas9	negative selection	8764175
43169172	43169195	8	+	27260156	PATU8988T	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.2094243147525625	[127]	[167,204,71,132]	3	hSpCas9	negative selection	8764176
43161454	43161477	8	-	27260156	PATU8988T	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	0.2487891214749129	[419]	[396,987,282,295]	4	hSpCas9	negative selection	8764177
43170598	43170621	8	-	27260156	T47D	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.1594842852968229	[669]	[1044,710,863,881]	3	hSpCas9	negative selection	8821165
43170622	43170645	8	+	27260156	T47D	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.050835734275228084	[411]	[511,457,473,407]	-1	hSpCas9	negative selection	8821166
43161440	43161463	8	+	27260156	T47D	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.7437121503987516	[84]	[169,190,144,154]	9	hSpCas9	negative selection	8821167
43169205	43169228	8	-	27260156	T47D	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.10474275980328773	[226]	[262,228,279,372]	2	hSpCas9	negative selection	8885426
43169172	43169195	8	+	27260156	T47D	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.49216375828631165	[127]	[188,243,194,207]	8	hSpCas9	negative selection	8885427
43161454	43161477	8	-	27260156	T47D	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.3364788227693368	[419]	[482,364,385,315]	-6	hSpCas9	negative selection	8885428
43170598	43170621	8	-	27260156	SU8686	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.23003282856020613	[669]	[738,751,822,810]	4	hSpCas9	negative selection	8942416
43170622	43170645	8	+	27260156	SU8686	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.32626765599886354	[411]	[423,374,611,693]	5	hSpCas9	negative selection	8942417
43161440	43161463	8	+	27260156	SU8686	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.06143912610163538	[84]	[65,43,128,127]	1	hSpCas9	negative selection	8942418
43169205	43169228	8	-	27260156	SU8686	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	-0.04279422296725466	[226]	[203,181,289,201]	0	hSpCas9	negative selection	9006677
43169172	43169195	8	+	27260156	SU8686	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.6062519420279804	[127]	[174,158,161,297]	8	hSpCas9	negative selection	9006678
43161454	43161477	8	-	27260156	SU8686	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.4927878167365157	[419]	[208,265,371,360]	-7	hSpCas9	negative selection	9006679
43170598	43170621	8	-	27260156	SKES1	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.22994612324471864	[669]	[904,780,748,716]	5	hSpCas9	negative selection	9063667
43170622	43170645	8	+	27260156	SKES1	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.24791490875977984	[411]	[458,382,322,247]	-5	hSpCas9	negative selection	9063668
43161440	43161463	8	+	27260156	SKES1	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.5763447855716604	[84]	[95,147,114,141]	9	hSpCas9	negative selection	9063669
43169205	43169228	8	-	27260156	SKES1	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.12340177869256996	[226]	[277,325,166,229]	2	hSpCas9	negative selection	9127928
43169172	43169195	8	+	27260156	SKES1	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.38132495600019656	[127]	[175,128,229,128]	7	hSpCas9	negative selection	9127929
43161454	43161477	8	-	27260156	SKES1	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.18469471377111255	[419]	[402,445,382,264]	-4	hSpCas9	negative selection	9127930
43170598	43170621	8	-	27260156	TOV112D	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.2987561130107478	[669]	[708,1129,899,631]	5	hSpCas9	negative selection	9184918
43170622	43170645	8	+	27260156	TOV112D	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	-0.09400661492854179	[411]	[313,651,288,350]	-2	hSpCas9	negative selection	9184919
43161440	43161463	8	+	27260156	TOV112D	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.3446378079736254	[84]	[180,61,74,108]	6	hSpCas9	negative selection	9184920
43169205	43169228	8	-	27260156	TOV112D	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.5938303031649553	[226]	[388,305,303,366]	9	hSpCas9	negative selection	9249179
43169172	43169195	8	+	27260156	TOV112D	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.35963392949315387	[127]	[158,321,86,128]	6	hSpCas9	negative selection	9249180
43161454	43161477	8	-	27260156	TOV112D	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.09959495375379504	[419]	[563,287,298,406]	-2	hSpCas9	negative selection	9249181
43170598	43170621	8	-	27260156	TC71	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.2088262905012771	[669]	[819,925,767,806]	5	hSpCas9	negative selection	9306169
43170622	43170645	8	+	27260156	TC71	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.20927328268963258	[411]	[518,354,656,505]	5	hSpCas9	negative selection	9306170
43161440	43161463	8	+	27260156	TC71	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.6932794699398852	[84]	[130,203,107,147]	9	hSpCas9	negative selection	9306171
43169205	43169228	8	-	27260156	TC71	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.17905203332246522	[226]	[226,239,310,326]	4	hSpCas9	negative selection	9370430
43169172	43169195	8	+	27260156	TC71	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.20153374839662597	[127]	[182,137,188,116]	5	hSpCas9	negative selection	9370431
43161454	43161477	8	-	27260156	TC71	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.3006729020808486	[419]	[331,329,388,413]	-7	hSpCas9	negative selection	9370432
43170598	43170621	8	-	27260156	TC32	viability	ATCGAGAGGGTCTGTCCTGCTGG	HGSNAT	ENSG00000165102	0.018466420631798597	[669]	[465,608,745,747]	0	hSpCas9	negative selection	9427420
43170622	43170645	8	+	27260156	TC32	viability	GTGATGTTCAGCCAGCAACGTGG	HGSNAT	ENSG00000165102	0.018411758195082145	[411]	[284,371,576,361]	0	hSpCas9	negative selection	9427421
43161440	43161463	8	+	27260156	TC32	viability	GTGAGCATTGCATTCCTTATTGG	HGSNAT	ENSG00000165102	0.4013071844322855	[84]	[102,38,181,132]	7	hSpCas9	negative selection	9427422
43169205	43169228	8	-	27260156	TC32	viability	ATCAGTTTCTCGAGAACTTATGG	HGSNAT	ENSG00000165102	0.40312468226624376	[226]	[307,219,360,253]	7	hSpCas9	negative selection	9491681
43169172	43169195	8	+	27260156	TC32	viability	GTTTGGATGACTTTAACAATTGG	HGSNAT	ENSG00000165102	0.30149675076240423	[127]	[160,67,228,170]	5	hSpCas9	negative selection	9491682
43161454	43161477	8	-	27260156	TC32	viability	TGATGACAGCAAGACCAATAAGG	HGSNAT	ENSG00000165102	-0.45829233338748065	[419]	[142,345,389,263]	-7	hSpCas9	negative selection	9491683
43158989	43159012	8	+	27869803	HPAFII	viability after 27 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	0.5801201096568067	[205]	[120,195,NaN]	5	hSpCas9	negative selection	9602763
43170668	43170691	8	-	27869803	HPAFII	viability after 27 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.3043662736739933	[403]	[207,141,NaN]	-2	hSpCas9	negative selection	9602764
43173739	43173762	8	-	27869803	HPAFII	viability after 27 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.17365952538745977	[164]	[5,135,NaN]	-1	hSpCas9	negative selection	9602765
43178112	43178135	8	+	27869803	HPAFII	viability after 27 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.48424328275454037	[461]	[183,164,NaN]	-4	hSpCas9	negative selection	9602766
43182237	43182260	8	-	27869803	HPAFII	viability after 27 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.3538916564807263	[196]	[103,155,NaN]	3	hSpCas9	negative selection	9602767
43191582	43191605	8	-	27869803	HPAFII	viability after 27 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.12463486510349522	[288]	[182,102,NaN]	-1	hSpCas9	negative selection	9602768
43158989	43159012	8	+	27869803	HPAFII	viability after 15 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.7639171549821325	[205]	[249,55,NaN]	-7	hSpCas9	negative selection	9685212
43170668	43170691	8	-	27869803	HPAFII	viability after 15 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.49050828136927543	[403]	[440,226,NaN]	-5	hSpCas9	negative selection	9685213
43173739	43173762	8	-	27869803	HPAFII	viability after 15 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.3963536669338188	[164]	[114,146,NaN]	-4	hSpCas9	negative selection	9685214
43178112	43178135	8	+	27869803	HPAFII	viability after 15 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.8688322324972201	[461]	[364,213,NaN]	-7	hSpCas9	negative selection	9685215
43182237	43182260	8	-	27869803	HPAFII	viability after 15 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.6378919344049258	[196]	[334,325,NaN]	7	hSpCas9	negative selection	9685216
43191582	43191605	8	-	27869803	HPAFII	viability after 15 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.11076386544663291	[288]	[389,223,NaN]	-1	hSpCas9	negative selection	9685217
43158989	43159012	8	+	27869803	ASPC1	viability after 36 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	0.5348181490972639	[523]	[277,249,264]	5	hSpCas9	negative selection	9767661
43170668	43170691	8	-	27869803	ASPC1	viability after 36 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.37390869874156235	[805]	[380,180,494]	4	hSpCas9	negative selection	9767662
43173739	43173762	8	-	27869803	ASPC1	viability after 36 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.9295607355941276	[351]	[333,90,274]	8	hSpCas9	negative selection	9767663
43178112	43178135	8	+	27869803	ASPC1	viability after 36 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	0.24880423067207413	[1028]	[699,409,243]	2	hSpCas9	negative selection	9767664
43182237	43182260	8	-	27869803	ASPC1	viability after 36 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	1.3801238387142218	[320]	[249,526,130]	9	hSpCas9	negative selection	9767665
43191582	43191605	8	-	27869803	ASPC1	viability after 36 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.180370045552949	[612]	[122,106,297]	-2	hSpCas9	negative selection	9767666
43158989	43159012	8	+	27869803	PATU8988S	viability after 35 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.32558354566127234	[488]	[225,87,NaN]	-3	hSpCas9	negative selection	9850110
43170668	43170691	8	-	27869803	PATU8988S	viability after 35 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.25294785131676595	[685]	[167,295,NaN]	-3	hSpCas9	negative selection	9850111
43173739	43173762	8	-	27869803	PATU8988S	viability after 35 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-1.6735891130712814	[296]	[35,38,NaN]	-8	hSpCas9	negative selection	9850112
43178112	43178135	8	+	27869803	PATU8988S	viability after 35 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.4773860379166975	[936]	[297,243,NaN]	-5	hSpCas9	negative selection	9850113
43182237	43182260	8	-	27869803	PATU8988S	viability after 35 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	-0.16812358900451974	[384]	[138,136,NaN]	-2	hSpCas9	negative selection	9850114
43191582	43191605	8	-	27869803	PATU8988S	viability after 35 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.2087154658306647	[546]	[247,132,NaN]	-2	hSpCas9	negative selection	9850115
43158989	43159012	8	+	27869803	PATU8988S	viability after 31 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	-0.35957576946454733	[488]	[202,86,NaN]	-4	hSpCas9	negative selection	9932559
43170668	43170691	8	-	27869803	PATU8988S	viability after 31 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.3676771201596093	[685]	[211,211,NaN]	-4	hSpCas9	negative selection	9932560
43173739	43173762	8	-	27869803	PATU8988S	viability after 31 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.6330964496712544	[296]	[78,72,NaN]	-6	hSpCas9	negative selection	9932561
43178112	43178135	8	+	27869803	PATU8988S	viability after 31 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.35185401929717197	[936]	[301,280,NaN]	-4	hSpCas9	negative selection	9932562
43182237	43182260	8	-	27869803	PATU8988S	viability after 31 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	-0.3742635847332414	[384]	[106,132,NaN]	-4	hSpCas9	negative selection	9932563
43191582	43191605	8	-	27869803	PATU8988S	viability after 31 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	-0.23756605427151364	[546]	[173,198,NaN]	-3	hSpCas9	negative selection	9932564
43158989	43159012	8	+	27869803	HPAFII	viability after 35 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	0.9023918725674835	[205]	[169,222,NaN]	6	hSpCas9	negative selection	10015008
43170668	43170691	8	-	27869803	HPAFII	viability after 35 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.23449091533018052	[403]	[210,131,NaN]	-1	hSpCas9	negative selection	10015009
43173739	43173762	8	-	27869803	HPAFII	viability after 35 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	0.0784342973896931	[164]	[11,173,NaN]	0	hSpCas9	negative selection	10015010
43178112	43178135	8	+	27869803	HPAFII	viability after 35 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-1.0375209788966968	[461]	[112,114,NaN]	-5	hSpCas9	negative selection	10015011
43182237	43182260	8	-	27869803	HPAFII	viability after 35 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.8102047525933156	[196]	[156,194,NaN]	5	hSpCas9	negative selection	10015012
43191582	43191605	8	-	27869803	HPAFII	viability after 35 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.06182741448137452	[288]	[163,139,NaN]	0	hSpCas9	negative selection	10015013
43158989	43159012	8	+	27869803	HPAFII	viability after 31 days	TAGTGAAATTGCCTGTGACCTGG	HGSNAT	ENSG00000165102	0.9842733429506922	[205]	[199,259,NaN]	7	hSpCas9	negative selection	10097457
43170668	43170691	8	-	27869803	HPAFII	viability after 31 days	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.006075526414761501	[403]	[231,218,NaN]	0	hSpCas9	negative selection	10097458
43173739	43173762	8	-	27869803	HPAFII	viability after 31 days	GGCAGACCGGCAACTCACCACGG	HGSNAT	ENSG00000165102	-0.032535904737459265	[164]	[1,186,NaN]	0	hSpCas9	negative selection	10097459
43178112	43178135	8	+	27869803	HPAFII	viability after 31 days	TGACTTCTATACTGCAACGGGGG	HGSNAT	ENSG00000165102	-0.06115139953107551	[461]	[248,247,NaN]	0	hSpCas9	negative selection	10097460
43182237	43182260	8	-	27869803	HPAFII	viability after 31 days	GAGGCACAATGTTCAGGCACAGG	HGSNAT	ENSG00000165102	0.296810808377305	[196]	[86,188,NaN]	2	hSpCas9	negative selection	10097461
43191582	43191605	8	-	27869803	HPAFII	viability after 31 days	TTCGCTTACGTAGGGCACCCAGG	HGSNAT	ENSG00000165102	0.3149725326184352	[288]	[296,97,NaN]	2	hSpCas9	negative selection	10097462
43140605	43140628	8	-	28162770	P31FUJ	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.046057168581097874	[135]	[164]	0	hSpCas9	negative selection	10168666
43172329	43172352	8	+	28162770	P31FUJ	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.3598959450863828	[247]	[373]	4	hSpCas9	negative selection	10168667
43170611	43170634	8	-	28162770	P31FUJ	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.1343985003533843	[84]	[90]	-1	hSpCas9	negative selection	10168668
43170668	43170691	8	-	28162770	P31FUJ	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.5642107734217663	[159]	[277]	6	hSpCas9	negative selection	10168669
43193753	43193776	8	+	28162770	P31FUJ	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.5531917256791921	[485]	[837]	6	hSpCas9	negative selection	10168670
43193772	43193795	8	+	28162770	P31FUJ	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.40262536328976534	[205]	[319]	4	hSpCas9	negative selection	10168671
43191548	43191571	8	-	28162770	P31FUJ	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.5491554288338155	[451]	[362]	-4	hSpCas9	negative selection	10168672
43191569	43191592	8	-	28162770	P31FUJ	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-0.7600492072792473	[97]	[67]	-5	hSpCas9	negative selection	10168673
43140570	43140593	8	-	28162770	P31FUJ	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.2947100241228777	[110]	[159]	3	hSpCas9	negative selection	10168674
43158655	43158678	8	-	28162770	P31FUJ	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.7090948410220531	[75]	[145]	7	hSpCas9	negative selection	10168675
43140605	43140628	8	-	28162770	TF1	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10338032
43172329	43172352	8	+	28162770	TF1	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10338033
43170611	43170634	8	-	28162770	TF1	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10338034
43170668	43170691	8	-	28162770	TF1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10338035
43193753	43193776	8	+	28162770	TF1	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[404]	1	hSpCas9	negative selection	10338036
43193772	43193795	8	+	28162770	TF1	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[356]	1	hSpCas9	negative selection	10338037
43191548	43191571	8	-	28162770	TF1	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[466]	1	hSpCas9	negative selection	10338038
43191569	43191592	8	-	28162770	TF1	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10338039
43140570	43140593	8	-	28162770	TF1	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10338040
43158655	43158678	8	-	28162770	TF1	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10338041
43140605	43140628	8	-	28162770	SKM1	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.8060295245910366	[32]	[101]	7	hSpCas9	negative selection	10507398
43172329	43172352	8	+	28162770	SKM1	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	1.233851536711512	[37]	[157]	9	hSpCas9	negative selection	10507399
43170611	43170634	8	-	28162770	SKM1	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	0.24212863939771	[21]	[45]	2	hSpCas9	negative selection	10507400
43170668	43170691	8	-	28162770	SKM1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.8423952701935556	[52]	[167]	7	hSpCas9	negative selection	10507401
43193753	43193776	8	+	28162770	SKM1	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.005682753110687999	[150]	[267]	0	hSpCas9	negative selection	10507402
43193772	43193795	8	+	28162770	SKM1	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.49548049183416465	[64]	[161]	5	hSpCas9	negative selection	10507403
43191548	43191571	8	-	28162770	SKM1	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.07448618451488953	[108]	[182]	0	hSpCas9	negative selection	10507404
43191569	43191592	8	-	28162770	SKM1	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.37593767958990343	[16]	[38]	3	hSpCas9	negative selection	10507405
43140570	43140593	8	-	28162770	SKM1	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.6768041589494362	[22]	[64]	6	hSpCas9	negative selection	10507406
43158655	43158678	8	-	28162770	SKM1	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.5499670793649525	[16]	[43]	5	hSpCas9	negative selection	10507407
43140605	43140628	8	-	28162770	SKM1	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.8060295245910366	[32]	[101]	7	hSpCas9	negative selection	10676764
43172329	43172352	8	+	28162770	SKM1	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	1.233851536711512	[37]	[157]	9	hSpCas9	negative selection	10676765
43170611	43170634	8	-	28162770	SKM1	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	0.24212863939771	[21]	[45]	2	hSpCas9	negative selection	10676766
43170668	43170691	8	-	28162770	SKM1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.8423952701935556	[52]	[167]	7	hSpCas9	negative selection	10676767
43193753	43193776	8	+	28162770	SKM1	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.005682753110687999	[150]	[267]	0	hSpCas9	negative selection	10676768
43193772	43193795	8	+	28162770	SKM1	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.49548049183416465	[64]	[161]	5	hSpCas9	negative selection	10676769
43191548	43191571	8	-	28162770	SKM1	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.07448618451488953	[108]	[182]	0	hSpCas9	negative selection	10676770
43191569	43191592	8	-	28162770	SKM1	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.37593767958990343	[16]	[38]	3	hSpCas9	negative selection	10676771
43140570	43140593	8	-	28162770	SKM1	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.6768041589494362	[22]	[64]	6	hSpCas9	negative selection	10676772
43158655	43158678	8	-	28162770	SKM1	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.5499670793649525	[16]	[43]	5	hSpCas9	negative selection	10676773
43140605	43140628	8	-	28162770	PL21	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-1.3206925488121202	[131]	[22]	-7	hSpCas9	negative selection	10846130
43172329	43172352	8	+	28162770	PL21	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.498363448785414	[134]	[82]	4	hSpCas9	negative selection	10846131
43170611	43170634	8	-	28162770	PL21	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.44622343089597916	[71]	[22]	-3	hSpCas9	negative selection	10846132
43170668	43170691	8	-	28162770	PL21	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.021802373230807776	[171]	[75]	0	hSpCas9	negative selection	10846133
43193753	43193776	8	+	28162770	PL21	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.7659298059356305	[403]	[298]	6	hSpCas9	negative selection	10846134
43193772	43193795	8	+	28162770	PL21	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.36257007938470837	[192]	[107]	3	hSpCas9	negative selection	10846135
43191548	43191571	8	-	28162770	PL21	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.845796669677539	[350]	[84]	-5	hSpCas9	negative selection	10846136
43191569	43191592	8	-	28162770	PL21	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-0.11106207380498367	[66]	[26]	-1	hSpCas9	negative selection	10846137
43140570	43140593	8	-	28162770	PL21	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.46862845041522194	[87]	[52]	4	hSpCas9	negative selection	10846138
43158655	43158678	8	-	28162770	PL21	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.7147127873190782	[41]	[29]	6	hSpCas9	negative selection	10846139
43140605	43140628	8	-	28162770	P31FUJ	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.046057168581097874	[135]	[164]	0	hSpCas9	negative selection	11015496
43172329	43172352	8	+	28162770	P31FUJ	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.3598959450863828	[247]	[373]	4	hSpCas9	negative selection	11015497
43170611	43170634	8	-	28162770	P31FUJ	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.1343985003533843	[84]	[90]	-1	hSpCas9	negative selection	11015498
43170668	43170691	8	-	28162770	P31FUJ	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.5642107734217663	[159]	[277]	6	hSpCas9	negative selection	11015499
43193753	43193776	8	+	28162770	P31FUJ	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.5531917256791921	[485]	[837]	6	hSpCas9	negative selection	11015500
43193772	43193795	8	+	28162770	P31FUJ	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.40262536328976534	[205]	[319]	4	hSpCas9	negative selection	11015501
43191548	43191571	8	-	28162770	P31FUJ	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.5491554288338155	[451]	[362]	-4	hSpCas9	negative selection	11015502
43191569	43191592	8	-	28162770	P31FUJ	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-0.7600492072792473	[97]	[67]	-5	hSpCas9	negative selection	11015503
43140570	43140593	8	-	28162770	P31FUJ	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.2947100241228777	[110]	[159]	3	hSpCas9	negative selection	11015504
43158655	43158678	8	-	28162770	P31FUJ	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.7090948410220531	[75]	[145]	7	hSpCas9	negative selection	11015505
43140605	43140628	8	-	28162770	OCIAML5	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.6121157781432445	[104]	[123]	-4	hSpCas9	negative selection	11184862
43172329	43172352	8	+	28162770	OCIAML5	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.2513367542845243	[90]	[137]	-2	hSpCas9	negative selection	11184863
43170611	43170634	8	-	28162770	OCIAML5	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-3.624656074760925	[81]	[11]	-9	hSpCas9	negative selection	11184864
43170668	43170691	8	-	28162770	OCIAML5	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.10570519374670569	[103]	[201]	0	hSpCas9	negative selection	11184865
43193753	43193776	8	+	28162770	OCIAML5	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.39714734038295463	[235]	[560]	3	hSpCas9	negative selection	11184866
43193772	43193795	8	+	28162770	OCIAML5	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	-0.35759460409074806	[158]	[223]	-3	hSpCas9	negative selection	11184867
43191548	43191571	8	-	28162770	OCIAML5	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.6330567889222012	[243]	[283]	-4	hSpCas9	negative selection	11184868
43191569	43191592	8	-	28162770	OCIAML5	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-2.1344663015647214	[89]	[36]	-8	hSpCas9	negative selection	11184869
43140570	43140593	8	-	28162770	OCIAML5	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	1.1903686954563997	[66]	[275]	8	hSpCas9	negative selection	11184870
43158655	43158678	8	-	28162770	OCIAML5	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.6296741495275493	[35]	[41]	-4	hSpCas9	negative selection	11184871
43140605	43140628	8	-	28162770	EOL1	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.3017053871782891	[327]	[212]	2	hSpCas9	negative selection	11354228
43172329	43172352	8	+	28162770	EOL1	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.21774414791458085	[141]	[86]	2	hSpCas9	negative selection	11354229
43170611	43170634	8	-	28162770	EOL1	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-1.1051995718235177	[97]	[23]	-6	hSpCas9	negative selection	11354230
43170668	43170691	8	-	28162770	EOL1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.3788981948742046	[361]	[247]	3	hSpCas9	negative selection	11354231
43193753	43193776	8	+	28162770	EOL1	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.30305939482426436	[779]	[506]	2	hSpCas9	negative selection	11354232
43193772	43193795	8	+	28162770	EOL1	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.10773815648488716	[420]	[238]	1	hSpCas9	negative selection	11354233
43191548	43191571	8	-	28162770	EOL1	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	0.2168422061371389	[422]	[258]	2	hSpCas9	negative selection	11354234
43191569	43191592	8	-	28162770	EOL1	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.6499253914615288	[74]	[61]	6	hSpCas9	negative selection	11354235
43140570	43140593	8	-	28162770	EOL1	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	1.7630843488764183	[84]	[151]	9	hSpCas9	negative selection	11354236
43158655	43158678	8	-	28162770	EOL1	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.6901620725446738	[48]	[15]	-5	hSpCas9	negative selection	11354237
43140605	43140628	8	-	28162770	MOLM13	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.33466455424920416	[224]	[128]	-2	hSpCas9	negative selection	11523594
43172329	43172352	8	+	28162770	MOLM13	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.19906649137388477	[180]	[113]	-1	hSpCas9	negative selection	11523595
43170611	43170634	8	-	28162770	MOLM13	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-1.914580255277834	[145]	[27]	-7	hSpCas9	negative selection	11523596
43170668	43170691	8	-	28162770	MOLM13	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.6029941046119309	[291]	[138]	-3	hSpCas9	negative selection	11523597
43193753	43193776	8	+	28162770	MOLM13	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.7644854235258829	[608]	[747]	6	hSpCas9	negative selection	11523598
43193772	43193795	8	+	28162770	MOLM13	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.8772803176822804	[319]	[424]	6	hSpCas9	negative selection	11523599
43191548	43191571	8	-	28162770	MOLM13	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.279467818468223	[417]	[248]	-2	hSpCas9	negative selection	11523600
43191569	43191592	8	-	28162770	MOLM13	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-6.232550336596514	[103]	[0]	-9	hSpCas9	negative selection	11523601
43140570	43140593	8	-	28162770	MOLM13	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	-0.5065755263482836	[111]	[56]	-3	hSpCas9	negative selection	11523602
43158655	43158678	8	-	28162770	MOLM13	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.31529922938227317	[73]	[42]	-2	hSpCas9	negative selection	11523603
43140605	43140628	8	-	28162770	HEL	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	1.3714368101829626	[174]	[289]	9	hSpCas9	negative selection	11692960
43172329	43172352	8	+	28162770	HEL	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.442599217511037	[192]	[167]	3	hSpCas9	negative selection	11692961
43170611	43170634	8	-	28162770	HEL	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.24622985561089927	[99]	[53]	-2	hSpCas9	negative selection	11692962
43170668	43170691	8	-	28162770	HEL	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.9764762291773528	[218]	[275]	8	hSpCas9	negative selection	11692963
43193753	43193776	8	+	28162770	HEL	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.931005274580256	[528]	[645]	7	hSpCas9	negative selection	11692964
43193772	43193795	8	+	28162770	HEL	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.5519733680771748	[327]	[307]	4	hSpCas9	negative selection	11692965
43191548	43191571	8	-	28162770	HEL	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.013528702793932257	[393]	[249]	0	hSpCas9	negative selection	11692966
43191569	43191592	8	-	28162770	HEL	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-2.208117728693834	[100]	[13]	-8	hSpCas9	negative selection	11692967
43140570	43140593	8	-	28162770	HEL	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.2994370863204274	[84]	[66]	2	hSpCas9	negative selection	11692968
43158655	43158678	8	-	28162770	HEL	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.05777633127920079	[62]	[41]	0	hSpCas9	negative selection	11692969
43140605	43140628	8	-	28162770	MV411	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.5953608542030822	[98]	[125]	5	hSpCas9	negative selection	11862326
43172329	43172352	8	+	28162770	MV411	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.2801917748724294	[110]	[76]	-2	hSpCas9	negative selection	11862327
43170611	43170634	8	-	28162770	MV411	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-1.382612839466919	[64]	[20]	-7	hSpCas9	negative selection	11862328
43170668	43170691	8	-	28162770	MV411	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.3654347601812266	[175]	[190]	3	hSpCas9	negative selection	11862329
43193753	43193776	8	+	28162770	MV411	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.45509519958019573	[477]	[551]	4	hSpCas9	negative selection	11862330
43193772	43193795	8	+	28162770	MV411	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	1.2966415487835452	[244]	[506]	9	hSpCas9	negative selection	11862331
43191548	43191571	8	-	28162770	MV411	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.602228176132793	[345]	[191]	-4	hSpCas9	negative selection	11862332
43191569	43191592	8	-	28162770	MV411	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-1.1624382433802898	[92]	[34]	-6	hSpCas9	negative selection	11862333
43140570	43140593	8	-	28162770	MV411	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.896940303698642	[50]	[79]	7	hSpCas9	negative selection	11862334
43158655	43158678	8	-	28162770	MV411	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.6488001131645424	[52]	[69]	6	hSpCas9	negative selection	11862335
43140605	43140628	8	-	28162770	MONOMAC1	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.2541807541631624	[102]	[98]	-2	hSpCas9	negative selection	12031692
43172329	43172352	8	+	28162770	MONOMAC1	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.559606926444262	[98]	[76]	-5	hSpCas9	negative selection	12031693
43170611	43170634	8	-	28162770	MONOMAC1	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.8889145516972219	[20]	[12]	-6	hSpCas9	negative selection	12031694
43170668	43170691	8	-	28162770	MONOMAC1	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.009414030407872823	[116]	[134]	0	hSpCas9	negative selection	12031695
43193753	43193776	8	+	28162770	MONOMAC1	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	1.2450065315278154	[257]	[700]	9	hSpCas9	negative selection	12031696
43193772	43193795	8	+	28162770	MONOMAC1	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.7319966315863027	[124]	[237]	7	hSpCas9	negative selection	12031697
43191548	43191571	8	-	28162770	MONOMAC1	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	0.19687736065353617	[171]	[225]	2	hSpCas9	negative selection	12031698
43191569	43191592	8	-	28162770	MONOMAC1	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	0.20958841240309	[42]	[56]	2	hSpCas9	negative selection	12031699
43140570	43140593	8	-	28162770	MONOMAC1	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	1.043971252444241	[43]	[103]	8	hSpCas9	negative selection	12031700
43158655	43158678	8	-	28162770	MONOMAC1	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.43372934327472734	[30]	[47]	4	hSpCas9	negative selection	12031701
43140605	43140628	8	-	28162770	OCIAML2	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	0.2597631150005588	[21]	[145]	2	hSpCas9	negative selection	12201058
43172329	43172352	8	+	28162770	OCIAML2	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	-0.8685938111620636	[27]	[84]	-6	hSpCas9	negative selection	12201059
43170611	43170634	8	-	28162770	OCIAML2	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-1.6310944974354071	[18]	[33]	-7	hSpCas9	negative selection	12201060
43170668	43170691	8	-	28162770	OCIAML2	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	-0.0016333425693299264	[40]	[226]	0	hSpCas9	negative selection	12201061
43193753	43193776	8	+	28162770	OCIAML2	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	0.6448473921777748	[68]	[597]	6	hSpCas9	negative selection	12201062
43193772	43193795	8	+	28162770	OCIAML2	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.04087051353797394	[46]	[267]	0	hSpCas9	negative selection	12201063
43191548	43191571	8	-	28162770	OCIAML2	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.40597686689990764	[59]	[250]	-3	hSpCas9	negative selection	12201064
43191569	43191592	8	-	28162770	OCIAML2	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-1.108059745857453	[6]	[17]	-6	hSpCas9	negative selection	12201065
43140570	43140593	8	-	28162770	OCIAML2	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	0.5882638638114075	[8]	[74]	6	hSpCas9	negative selection	12201066
43158655	43158678	8	-	28162770	OCIAML2	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	0.5649940844885601	[9]	[81]	5	hSpCas9	negative selection	12201067
43140605	43140628	8	-	28162770	OCIAML3	viability	GGTGTGCACTCACCTCGTGGCGG	HGSNAT	ENSG00000165102	-0.5279184498663907	[31]	[66]	-4	hSpCas9	negative selection	12370424
43172329	43172352	8	+	28162770	OCIAML3	viability	GTCTTTGTCAATTATGGAGGAGG	HGSNAT	ENSG00000165102	0.861444127400589	[32]	[180]	7	hSpCas9	negative selection	12370425
43170611	43170634	8	-	28162770	OCIAML3	viability	GCTGAACATCACCATCGAGAGGG	HGSNAT	ENSG00000165102	-0.4095830691867357	[21]	[49]	-3	hSpCas9	negative selection	12370426
43170668	43170691	8	-	28162770	OCIAML3	viability	TGAAGGTGTCCACGCTGCGGAGG	HGSNAT	ENSG00000165102	0.22156778853840947	[49]	[175]	2	hSpCas9	negative selection	12370427
43193753	43193776	8	+	28162770	OCIAML3	viability	TAAGGTACTTTACCACACCGAGG	HGSNAT	ENSG00000165102	2.3902250438175203	[114]	[1819]	9	hSpCas9	negative selection	12370428
43193772	43193795	8	+	28162770	OCIAML3	viability	GAGGTGGCCTATGACCCCGAGGG	HGSNAT	ENSG00000165102	0.18814672760829843	[65]	[226]	1	hSpCas9	negative selection	12370429
43191548	43191571	8	-	28162770	OCIAML3	viability	GGAATGTCAAGCCCAGCCACAGG	HGSNAT	ENSG00000165102	-0.41256076898663124	[96]	[219]	-3	hSpCas9	negative selection	12370430
43191569	43191592	8	-	28162770	OCIAML3	viability	GGCACCCAGGGACTGGCAGGAGG	HGSNAT	ENSG00000165102	-0.1954582638338883	[32]	[86]	-1	hSpCas9	negative selection	12370431
43140570	43140593	8	-	28162770	OCIAML3	viability	ATCGCGCCCCGAAGAGCCGCCGG	HGSNAT	ENSG00000165102	-0.774579885965984	[16]	[29]	-5	hSpCas9	negative selection	12370432
43158655	43158678	8	-	28162770	OCIAML3	viability	GCTGCAGGATAGATCCGTGCTGG	HGSNAT	ENSG00000165102	-0.07317547702272287	[22]	[65]	0	hSpCas9	negative selection	12370433