Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 89781
• Symbol: HPS4
• Description: HPS4 biogenesis of lysosomal organelles complex 3 subunit 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HPS4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
26457927	26457950	22	+	26472758	Jiyoye	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	2.135873359688479	[34]	[115]	9	hSpCas9	negative selection	73943
26464330	26464353	22	+	26472758	Jiyoye	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.6587141485018377	[41]	[49]	5	hSpCas9	negative selection	73944
26479290	26479313	22	-	26472758	Jiyoye	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.9746504554981885	[82]	[122]	6	hSpCas9	negative selection	73945
26477064	26477087	22	+	26472758	Jiyoye	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	5.407175381505873	[0]	[31]	9	hSpCas9	negative selection	73946
26470785	26470808	22	+	26472758	Jiyoye	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.026571379290903696	[344]	[264]	0	hSpCas9	negative selection	73947
26465468	26465491	22	-	26472758	Jiyoye	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	2.4775647093972717	[49]	[209]	9	hSpCas9	negative selection	73948
26464767	26464790	22	-	26472758	Jiyoye	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.3482816924523049	[74]	[71]	2	hSpCas9	negative selection	73949
26464590	26464613	22	-	26472758	Jiyoye	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	1.3880665585581686	[75]	[149]	8	hSpCas9	negative selection	73950
26464574	26464597	22	+	26472758	Jiyoye	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	-0.5232836852410495	[161]	[84]	-4	hSpCas9	negative selection	73951
26464460	26464483	22	+	26472758	Jiyoye	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.266312845666024	[128]	[116]	2	hSpCas9	negative selection	73952
26457927	26457950	22	+	26472758	KBM7	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.13671551612602362	[211,120]	[91,76]	1	hSpCas9	negative selection	265061
26464330	26464353	22	+	26472758	KBM7	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.1601235957872329	[101,253]	[96,98]	1	hSpCas9	negative selection	265062
26479290	26479313	22	-	26472758	KBM7	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.6410369850993887	[328,338]	[265,228]	7	hSpCas9	negative selection	265063
26477064	26477087	22	+	26472758	KBM7	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.6482397789108785	[195,124]	[178,59]	7	hSpCas9	negative selection	265064
26470785	26470808	22	+	26472758	KBM7	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.23172197863195465	[1132,824]	[761,330]	2	hSpCas9	negative selection	265065
26465468	26465491	22	-	26472758	KBM7	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.145540593152797	[640,429]	[344,210]	1	hSpCas9	negative selection	265066
26464767	26464790	22	-	26472758	KBM7	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.47025213152550494	[773,624]	[141,319]	-4	hSpCas9	negative selection	265067
26464590	26464613	22	-	26472758	KBM7	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.13945007276963206	[356,347]	[216,152]	1	hSpCas9	negative selection	265068
26464574	26464597	22	+	26472758	KBM7	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.23625556226668287	[653,591]	[354,335]	2	hSpCas9	negative selection	265069
26464460	26464483	22	+	26472758	KBM7	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.4413034938428344	[440,370]	[301,218]	5	hSpCas9	negative selection	265070
26457927	26457950	22	+	26472758	Raji	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	-0.241766028248787	[106]	[20]	-2	hSpCas9	negative selection	456179
26464330	26464353	22	+	26472758	Raji	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-2.0355744184684434	[158]	[8]	-8	hSpCas9	negative selection	456180
26479290	26479313	22	-	26472758	Raji	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-1.0748197958471497	[235]	[25]	-7	hSpCas9	negative selection	456181
26477064	26477087	22	+	26472758	Raji	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.6360778164480105	[60]	[21]	6	hSpCas9	negative selection	456182
26470785	26470808	22	+	26472758	Raji	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.7174370170575859	[303]	[115]	6	hSpCas9	negative selection	456183
26465468	26465491	22	-	26472758	Raji	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	-0.029155297574166072	[298]	[67]	0	hSpCas9	negative selection	456184
26464767	26464790	22	-	26472758	Raji	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.0846352369193295	[328]	[71]	0	hSpCas9	negative selection	456185
26464590	26464613	22	-	26472758	Raji	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-1.107629355597251	[259]	[27]	-7	hSpCas9	negative selection	456186
26464574	26464597	22	+	26472758	Raji	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.303018655921807	[240]	[68]	3	hSpCas9	negative selection	456187
26464460	26464483	22	+	26472758	Raji	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.47295235838814353	[266]	[85]	4	hSpCas9	negative selection	456188
26457927	26457950	22	+	26472758	K562	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.6888308290788042	[157]	[214]	5	hSpCas9	negative selection	647297
26464330	26464353	22	+	26472758	K562	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-1.3955851366126713	[186]	[59]	-6	hSpCas9	negative selection	647298
26479290	26479313	22	-	26472758	K562	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-1.2991238456747287	[308]	[105]	-6	hSpCas9	negative selection	647299
26477064	26477087	22	+	26472758	K562	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.8980939784716171	[81]	[128]	7	hSpCas9	negative selection	647300
26470785	26470808	22	+	26472758	K562	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.035323128943456794	[755]	[653]	0	hSpCas9	negative selection	647301
26465468	26465491	22	-	26472758	K562	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.22543562429887404	[458]	[452]	1	hSpCas9	negative selection	647302
26464767	26464790	22	-	26472758	K562	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.3245890763504301	[454]	[480]	2	hSpCas9	negative selection	647303
26464590	26464613	22	-	26472758	K562	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.34054377305470923	[320]	[213]	-2	hSpCas9	negative selection	647304
26464574	26464597	22	+	26472758	K562	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.620879194834595	[378]	[491]	5	hSpCas9	negative selection	647305
26464460	26464483	22	+	26472758	K562	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.6392217432052367	[358]	[471]	5	hSpCas9	negative selection	647306
26470785	26470808	22	+	26627737	DLD1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.5733731516949979	[523]	[177,217,321]	6	hSpCas9	negative selection	817119
26470881	26470904	22	+	26627737	DLD1	viability	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.2522180568420789	[277]	[98,35,80]	-3	hSpCas9	negative selection	817120
26472304	26472327	22	+	26627737	DLD1	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.5935452253990221	[253]	[27,89,42]	-5	hSpCas9	negative selection	817121
26472830	26472853	22	+	26627737	DLD1	viability	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.573788870237884	[496]	[268,191,230]	6	hSpCas9	negative selection	817122
26476977	26477000	22	+	26627737	DLD1	viability	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.25938195472672787	[580]	[208,158,272]	2	hSpCas9	negative selection	817123
26479308	26479331	22	-	26627737	DLD1	viability	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.4604801616171952	[56]	[19,18,32]	5	hSpCas9	negative selection	817124
26470785	26470808	22	+	26627737	GBM cells	viability after 5 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.5161236243931582	[399]	[156,142]	-7	hSpCas9	negative selection	899434
26470881	26470904	22	+	26627737	GBM cells	viability after 5 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	1.0404680190997049	[96]	[98,114]	9	hSpCas9	negative selection	899435
26472304	26472327	22	+	26627737	GBM cells	viability after 5 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.1661811533361991	[135]	[66,62]	-3	hSpCas9	negative selection	899436
26472830	26472853	22	+	26627737	GBM cells	viability after 5 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.3295482292155478	[390]	[306,219]	5	hSpCas9	negative selection	899437
26476977	26477000	22	+	26627737	GBM cells	viability after 5 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	-0.26678654069490143	[340]	[161,141]	-4	hSpCas9	negative selection	899438
26479308	26479331	22	-	26627737	GBM cells	viability after 5 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-0.17247075835107983	[144]	[68,68]	-3	hSpCas9	negative selection	899439
26470785	26470808	22	+	26627737	GBM cells	viability after 13 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.0656037421905784	[399]	[213,201]	-1	hSpCas9	negative selection	981749
26470881	26470904	22	+	26627737	GBM cells	viability after 13 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.825563339092282	[96]	[84,99]	8	hSpCas9	negative selection	981750
26472304	26472327	22	+	26627737	GBM cells	viability after 13 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.7870110050026368	[135]	[55,31]	-7	hSpCas9	negative selection	981751
26472830	26472853	22	+	26627737	GBM cells	viability after 13 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.14592410139825673	[390]	[317,166]	1	hSpCas9	negative selection	981752
26476977	26477000	22	+	26627737	GBM cells	viability after 13 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.013723616840873976	[340]	[247,136]	0	hSpCas9	negative selection	981753
26479308	26479331	22	-	26627737	GBM cells	viability after 13 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.07851097764855797	[144]	[92,74]	1	hSpCas9	negative selection	981754
26470785	26470808	22	+	26627737	GBM cells	viability after 21 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.012599619322340772	[399]	[228,202]	0	hSpCas9	negative selection	1064064
26470881	26470904	22	+	26627737	GBM cells	viability after 21 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	1.0925334242261402	[96]	[126,98]	9	hSpCas9	negative selection	1064065
26472304	26472327	22	+	26627737	GBM cells	viability after 21 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.2970377250686902	[135]	[95,85]	3	hSpCas9	negative selection	1064066
26472830	26472853	22	+	26627737	GBM cells	viability after 21 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.13201802945270769	[390]	[237,227]	1	hSpCas9	negative selection	1064067
26476977	26477000	22	+	26627737	GBM cells	viability after 21 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	-0.357581748761103	[340]	[165,124]	-3	hSpCas9	negative selection	1064068
26479308	26479331	22	-	26627737	GBM cells	viability after 21 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.027053290751907322	[144]	[73,85]	0	hSpCas9	negative selection	1064069
26470785	26470808	22	+	26627737	RPE1	viability after 9 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.3257457689687466	[833]	[259,413]	2	hSpCas9	negative selection	1146379
26470881	26470904	22	+	26627737	RPE1	viability after 9 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.2884145763882531	[353]	[92,189]	2	hSpCas9	negative selection	1146380
26472304	26472327	22	+	26627737	RPE1	viability after 9 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	1.6563869662800157	[175]	[174,171]	8	hSpCas9	negative selection	1146381
26472830	26472853	22	+	26627737	RPE1	viability after 9 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-0.00989054525034494	[1406]	[333,570]	0	hSpCas9	negative selection	1146382
26476977	26477000	22	+	26627737	RPE1	viability after 9 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.1370990545265358	[1495]	[473,567]	1	hSpCas9	negative selection	1146383
26479308	26479331	22	-	26627737	RPE1	viability after 9 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-0.5994242179073223	[482]	[125,65]	-4	hSpCas9	negative selection	1146384
26470785	26470808	22	+	26627737	RPE1	viability after 12 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.5969844777338718	[833]	[301,377]	4	hSpCas9	negative selection	1228694
26470881	26470904	22	+	26627737	RPE1	viability after 12 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.8247436537402435	[353]	[149,187]	5	hSpCas9	negative selection	1228695
26472304	26472327	22	+	26627737	RPE1	viability after 12 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.4165744794461488	[175]	[66,58]	2	hSpCas9	negative selection	1228696
26472830	26472853	22	+	26627737	RPE1	viability after 12 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.0469363139209068	[1406]	[322,461]	0	hSpCas9	negative selection	1228697
26476977	26477000	22	+	26627737	RPE1	viability after 12 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.2197578138562606	[1495]	[418,519]	1	hSpCas9	negative selection	1228698
26479308	26479331	22	-	26627737	RPE1	viability after 12 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-0.5192390397253682	[482]	[91,88]	-4	hSpCas9	negative selection	1228699
26470785	26470808	22	+	26627737	RPE1	viability after 15 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.17949444988377916	[833]	[425,113]	1	hSpCas9	negative selection	1311009
26470881	26470904	22	+	26627737	RPE1	viability after 15 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.7419072602808233	[353]	[140,192]	4	hSpCas9	negative selection	1311010
26472304	26472327	22	+	26627737	RPE1	viability after 15 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.3757188818921884	[175]	[30,96]	2	hSpCas9	negative selection	1311011
26472830	26472853	22	+	26627737	RPE1	viability after 15 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.00889474107098498	[1406]	[373,425]	0	hSpCas9	negative selection	1311012
26476977	26477000	22	+	26627737	RPE1	viability after 15 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	-0.07212221820418974	[1495]	[455,350]	0	hSpCas9	negative selection	1311013
26479308	26479331	22	-	26627737	RPE1	viability after 15 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-1.1094091978950331	[482]	[44,80]	-6	hSpCas9	negative selection	1311014
26470785	26470808	22	+	26627737	RPE1	viability after 18 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.32887582921374975	[833]	[302,260]	2	hSpCas9	negative selection	1393324
26470881	26470904	22	+	26627737	RPE1	viability after 18 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.9225884010594972	[353]	[168,193]	5	hSpCas9	negative selection	1393325
26472304	26472327	22	+	26627737	RPE1	viability after 18 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.3161209231237725	[175]	[62,54]	2	hSpCas9	negative selection	1393326
26472830	26472853	22	+	26627737	RPE1	viability after 18 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-0.2327977230623819	[1406]	[384,256]	-1	hSpCas9	negative selection	1393327
26476977	26477000	22	+	26627737	RPE1	viability after 18 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.40299590046772726	[1495]	[382,694]	2	hSpCas9	negative selection	1393328
26479308	26479331	22	-	26627737	RPE1	viability after 18 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-1.139171016598774	[482]	[78,37]	-6	hSpCas9	negative selection	1393329
26470785	26470808	22	+	26627737	HeLa	viability after 8 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-1.0900083087757313	[869]	[115,197,203]	-8	hSpCas9	negative selection	1475639
26470881	26470904	22	+	26627737	HeLa	viability after 8 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.12103567999217335	[231]	[219,73,62]	1	hSpCas9	negative selection	1475640
26472304	26472327	22	+	26627737	HeLa	viability after 8 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.2317019126654667	[117]	[107,61,23]	2	hSpCas9	negative selection	1475641
26472830	26472853	22	+	26627737	HeLa	viability after 8 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.34171881563612033	[500]	[367,278,206]	3	hSpCas9	negative selection	1475642
26476977	26477000	22	+	26627737	HeLa	viability after 8 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.25214015459030475	[405]	[356,177,133]	2	hSpCas9	negative selection	1475643
26479308	26479331	22	-	26627737	HeLa	viability after 8 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-0.5995013741506549	[258]	[107,54,67]	-5	hSpCas9	negative selection	1475644
26470785	26470808	22	+	26627737	HeLa	viability after 12 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.3893171557480817	[869]	[398,171,266]	-3	hSpCas9	negative selection	1557954
26470881	26470904	22	+	26627737	HeLa	viability after 12 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.13678559375895827	[231]	[53,102,157]	1	hSpCas9	negative selection	1557955
26472304	26472327	22	+	26627737	HeLa	viability after 12 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.722556489706625	[117]	[78,64,98]	6	hSpCas9	negative selection	1557956
26472830	26472853	22	+	26627737	HeLa	viability after 12 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.5601603965557707	[500]	[314,277,325]	5	hSpCas9	negative selection	1557957
26476977	26477000	22	+	26627737	HeLa	viability after 12 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.3583777581496751	[405]	[204,233,203]	3	hSpCas9	negative selection	1557958
26479308	26479331	22	-	26627737	HeLa	viability after 12 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-1.5495764015143698	[258]	[6,34,66]	-8	hSpCas9	negative selection	1557959
26470785	26470808	22	+	26627737	HeLa	viability after 15 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-1.6989820165789955	[869]	[42,104,185]	-9	hSpCas9	negative selection	1640269
26470881	26470904	22	+	26627737	HeLa	viability after 15 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.47801590035114305	[231]	[22,64,119]	-4	hSpCas9	negative selection	1640270
26472304	26472327	22	+	26627737	HeLa	viability after 15 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.3970505530524062	[117]	[54,45,90]	3	hSpCas9	negative selection	1640271
26472830	26472853	22	+	26627737	HeLa	viability after 15 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.45596586081855534	[500]	[188,449,194]	4	hSpCas9	negative selection	1640272
26476977	26477000	22	+	26627737	HeLa	viability after 15 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.41272852173034963	[405]	[240,123,300]	3	hSpCas9	negative selection	1640273
26479308	26479331	22	-	26627737	HeLa	viability after 15 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-1.682475704414549	[258]	[21,27,49]	-9	hSpCas9	negative selection	1640274
26470785	26470808	22	+	26627737	HeLa	viability after 18 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-1.6235215215303365	[869]	[36,90,185]	-8	hSpCas9	negative selection	1722584
26470881	26470904	22	+	26627737	HeLa	viability after 18 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.49883302677516994	[231]	[14,51,119]	-4	hSpCas9	negative selection	1722585
26472304	26472327	22	+	26627737	HeLa	viability after 18 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.45028894737645087	[117]	[39,39,90]	4	hSpCas9	negative selection	1722586
26472830	26472853	22	+	26627737	HeLa	viability after 18 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.4615168857283018	[500]	[130,369,194]	4	hSpCas9	negative selection	1722587
26476977	26477000	22	+	26627737	HeLa	viability after 18 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.4253365667636936	[405]	[161,106,300]	3	hSpCas9	negative selection	1722588
26479308	26479331	22	-	26627737	HeLa	viability after 18 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-1.7215889135885583	[258]	[13,21,49]	-9	hSpCas9	negative selection	1722589
26470785	26470808	22	+	26627737	HCT116	viability after 6 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.029623030387577853	[743]	[188,80]	0	hSpCas9	negative selection	1804899
26470881	26470904	22	+	26627737	HCT116	viability after 6 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-3.3963306199044823	[438]	[12,2]	-9	hSpCas9	negative selection	1804900
26472304	26472327	22	+	26627737	HCT116	viability after 6 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-2.916393297867087	[286]	[14,0]	-9	hSpCas9	negative selection	1804901
26472830	26472853	22	+	26627737	HCT116	viability after 6 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.12669631232079875	[825]	[173,123]	0	hSpCas9	negative selection	1804902
26476977	26477000	22	+	26627737	HCT116	viability after 6 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	-1.5922567419860938	[870]	[105,11]	-7	hSpCas9	negative selection	1804903
26479308	26479331	22	-	26627737	HCT116	viability after 6 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-4.249602980087027	[241]	[1,1]	-9	hSpCas9	negative selection	1804904
26470785	26470808	22	+	26627737	HCT116	viability after 8 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.42814252602491326	[548]	[243,218,211]	-5	hSpCas9	negative selection	1887214
26470881	26470904	22	+	26627737	HCT116	viability after 8 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.7324211426552367	[92]	[79,62,111]	7	hSpCas9	negative selection	1887215
26472304	26472327	22	+	26627737	HCT116	viability after 8 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.32839879764511437	[115]	[78,101,59]	3	hSpCas9	negative selection	1887216
26472830	26472853	22	+	26627737	HCT116	viability after 8 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-0.2631856173720786	[576]	[263,285,244]	-3	hSpCas9	negative selection	1887217
26476977	26477000	22	+	26627737	HCT116	viability after 8 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.6016948644039377	[231]	[183,219,177]	6	hSpCas9	negative selection	1887218
26479308	26479331	22	-	26627737	HCT116	viability after 8 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.436455110899857	[111]	[65,80,102]	4	hSpCas9	negative selection	1887219
26470785	26470808	22	+	26627737	HCT116	viability after 9 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.43564965136528394	[743]	[242,288]	3	hSpCas9	negative selection	1969529
26470881	26470904	22	+	26627737	HCT116	viability after 9 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.6139166408928209	[438]	[151,16]	-4	hSpCas9	negative selection	1969530
26472304	26472327	22	+	26627737	HCT116	viability after 9 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-2.0487084324784472	[286]	[3,29]	-8	hSpCas9	negative selection	1969531
26472830	26472853	22	+	26627737	HCT116	viability after 9 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.545787620550698	[825]	[264,366]	4	hSpCas9	negative selection	1969532
26476977	26477000	22	+	26627737	HCT116	viability after 9 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.0501093037394682	[870]	[361,144]	0	hSpCas9	negative selection	1969533
26479308	26479331	22	-	26627737	HCT116	viability after 9 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	1.096909653691573	[241]	[221,71]	7	hSpCas9	negative selection	1969534
26470785	26470808	22	+	26627737	HCT116	viability after 12 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.7733593259538916	[548]	[251,82,161]	-7	hSpCas9	negative selection	2051844
26470881	26470904	22	+	26627737	HCT116	viability after 12 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.1751873512890778	[92]	[44,77,43]	1	hSpCas9	negative selection	2051845
26472304	26472327	22	+	26627737	HCT116	viability after 12 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.5679563567792021	[115]	[44,39,37]	-6	hSpCas9	negative selection	2051846
26472830	26472853	22	+	26627737	HCT116	viability after 12 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-0.782982138422162	[576]	[90,251,194]	-7	hSpCas9	negative selection	2051847
26476977	26477000	22	+	26627737	HCT116	viability after 12 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.921945162873611	[231]	[234,203,252]	7	hSpCas9	negative selection	2051848
26479308	26479331	22	-	26627737	HCT116	viability after 12 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.4749644285099629	[111]	[82,109,52]	4	hSpCas9	negative selection	2051849
26470785	26470808	22	+	26627737	HCT116	viability after 15 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.8970879365527419	[548]	[314,71,138]	-7	hSpCas9	negative selection	2134159
26470881	26470904	22	+	26627737	HCT116	viability after 15 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.24919637271432737	[92]	[45,48,39]	-3	hSpCas9	negative selection	2134160
26472304	26472327	22	+	26627737	HCT116	viability after 15 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.10734787984040839	[115]	[78,78,29]	-1	hSpCas9	negative selection	2134161
26472830	26472853	22	+	26627737	HCT116	viability after 15 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-0.24909114552344913	[576]	[314,257,267]	-3	hSpCas9	negative selection	2134162
26476977	26477000	22	+	26627737	HCT116	viability after 15 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.8954534961419688	[231]	[313,223,213]	7	hSpCas9	negative selection	2134163
26479308	26479331	22	-	26627737	HCT116	viability after 15 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.14422764278450795	[111]	[109,37,69]	1	hSpCas9	negative selection	2134164
26470785	26470808	22	+	26627737	HCT116	viability after 18 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.40767750351400656	[548]	[223,217,154]	-4	hSpCas9	negative selection	2216474
26470881	26470904	22	+	26627737	HCT116	viability after 18 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.7427384355654248	[92]	[62,111,46]	6	hSpCas9	negative selection	2216475
26472304	26472327	22	+	26627737	HCT116	viability after 18 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.00854074540253813	[115]	[52,76,36]	0	hSpCas9	negative selection	2216476
26472830	26472853	22	+	26627737	HCT116	viability after 18 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	-1.290547757272025	[576]	[69,132,138]	-8	hSpCas9	negative selection	2216477
26476977	26477000	22	+	26627737	HCT116	viability after 18 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.7712164803566701	[231]	[202,248,114]	6	hSpCas9	negative selection	2216478
26479308	26479331	22	-	26627737	HCT116	viability after 18 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	-0.388257194614285	[111]	[52,28,42]	-4	hSpCas9	negative selection	2216479
26483718	26483741	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGCTGCTGCCCACATTTCTGG	HPS4	ENSG00000100099	-2.2754530832453606	[50,110]	[3,2]	-9	dCas9-VP64	positive selection	2389279
26483691	26483714	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTCCCGAACCCCGAGCACTGG	HPS4	ENSG00000100099	0.8962706079473588	[97,105]	[13,70]	3	dCas9-VP64	positive selection	2389280
26483785	26483808	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGGCGGCGCGTGACCTAAGG	HPS4	ENSG00000100099	0.33030352717378864	[49,21]	[5,12]	1	dCas9-VP64	positive selection	2389281
26475376	26475399	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTTTTGTTGCCCAGG	HPS4	ENSG00000100099	-0.7818591031535113	[55,228]	[16,18]	-4	dCas9-VP64	positive selection	2393601
26473509	26473532	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGAGTGG	HPS4	ENSG00000100099	-0.7112509309644206	[46,33]	[6,2]	-4	dCas9-VP64	positive selection	2394249
26479820	26479843	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGCCCACAGTGTGCTCCGCGG	HPS4	ENSG00000100099	0.3005819212669638	[6,29]	[6,1]	1	dCas9-VP64	positive selection	2467783
26479851	26479874	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAACACGCAGTTTCAATGCAGG	HPS4	ENSG00000100099	-1.3905642230457587	[303,110]	[15,17]	-7	dCas9-VP64	positive selection	2467784
26479837	26479860	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGTGTTTGCTCAGCAACCGCGG	HPS4	ENSG00000100099	0.5051712845224361	[1,19]	[2,2]	2	dCas9-VP64	positive selection	2467785
26483718	26483741	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGCTGCTGCCCACATTTCTGG	HPS4	ENSG00000100099	-0.9663503055058845	[268,42]	[36,15]	-8	dCas9-VP64	positive selection	2484534
26483691	26483714	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTCCCGAACCCCGAGCACTGG	HPS4	ENSG00000100099	1.5034054065461462	[218,178]	[318,58]	8	dCas9-VP64	positive selection	2484535
26483785	26483808	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGGCGGCGCGTGACCTAAGG	HPS4	ENSG00000100099	-0.4005382666641506	[33,116]	[20,14]	-4	dCas9-VP64	positive selection	2484536
26475376	26475399	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTTTTGTTGCCCAGG	HPS4	ENSG00000100099	0.08408385798482881	[154,122]	[44,50]	0	dCas9-VP64	positive selection	2488856
26473509	26473532	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGAGTGG	HPS4	ENSG00000100099	-0.5384167306991928	[64,169]	[16,33]	-5	dCas9-VP64	positive selection	2489504
26479820	26479843	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGCCCACAGTGTGCTCCGCGG	HPS4	ENSG00000100099	0.47015563760989165	[123,192]	[72,69]	3	dCas9-VP64	positive selection	2563038
26479851	26479874	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAACACGCAGTTTCAATGCAGG	HPS4	ENSG00000100099	-0.3603992695648767	[136,65]	[21,28]	-4	dCas9-VP64	positive selection	2563039
26479837	26479860	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGTGTTTGCTCAGCAACCGCGG	HPS4	ENSG00000100099	0.6006063893264342	[30,35]	[20,11]	4	dCas9-VP64	positive selection	2563040
26472306	26472329	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	0.29399777502192037	[3,2]	[3,3]	6	hSpCas9	positive selection	2994098
26466219	26466242	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	0.1841437799752526	[2,2]	[3,1]	4	hSpCas9	positive selection	2994099
26470786	26470809	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.0669099868524082	[2,2]	[1,2]	-1	hSpCas9	positive selection	2994100
26464770	26464793	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	-0.12264040970862025	[3,2]	[2,1]	-2	hSpCas9	positive selection	2994101
26472306	26472329	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	0.35556288568556466	[3,3]	[4,2]	6	hSpCas9	positive selection	3061956
26466219	26466242	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	0.2010667434378722	[2,2]	[2,1]	3	hSpCas9	positive selection	3061957
26470786	26470809	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.021691486372289626	[2,2]	[2,1]	0	hSpCas9	positive selection	3061958
26464770	26464793	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	-0.611383537896235	[3,3]	[2,0]	-8	hSpCas9	positive selection	3061959
26477006	26477029		-	24336571	A375	resistance to PLX after 7 days	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	0.17818533619513727	[10,10]	[11,12]	5	hSpCas9	positive selection	3119722
26481724	26481747		+	24336571	A375	resistance to PLX after 7 days	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.028833792549968595	[17,18]	[17,17]	-1	hSpCas9	positive selection	3119723
26481738	26481761		-	24336571	A375	resistance to PLX after 7 days	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.2667586296376786	[10,9]	[7,8]	-7	hSpCas9	positive selection	3119724
26472304	26472327		+	24336571	A375	resistance to PLX after 7 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.19058987862913068	[9,11]	[9,8]	-6	hSpCas9	positive selection	3119725
26477006	26477029		-	24336571	A375	resistance to PLX after 14 days	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.26766489954988204	[10,10]	[3,3]	-3	hSpCas9	positive selection	3177515
26481724	26481747		+	24336571	A375	resistance to PLX after 14 days	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.2946543779139445	[16,16]	[6,4]	-3	hSpCas9	positive selection	3177516
26481738	26481761		-	24336571	A375	resistance to PLX after 14 days	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.4470372949325168	[7,8]	[3,5]	4	hSpCas9	positive selection	3177517
26472304	26472327		+	24336571	A375	resistance to PLX after 14 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-1.5086988506705983	[19,9]	[1,1]	-9	hSpCas9	positive selection	3177518
26477006	26477029		-	24336571	A375	viability after 7 days	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.28026525500654553	[13]	[10,10]	-4	hSpCas9	negative selection	3235308
26481724	26481747		+	24336571	A375	viability after 7 days	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.9240851340099008	[9]	[17,18]	9	hSpCas9	negative selection	3235309
26481738	26481761		-	24336571	A375	viability after 7 days	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.07579231668764824	[11]	[10,9]	-1	hSpCas9	negative selection	3235310
26472304	26472327		+	24336571	A375	viability after 7 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.016375182912983566	[10]	[9,11]	0	hSpCas9	negative selection	3235311
26477006	26477029		-	24336571	A375	viability after 14 days	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.27055387183981466	[13]	[10,10]	-3	hSpCas9	negative selection	3293101
26481724	26481747		+	24336571	A375	viability after 14 days	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.822660550567773	[9]	[16,16]	9	hSpCas9	negative selection	3293102
26481738	26481761		-	24336571	A375	viability after 14 days	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.35010729459113904	[11]	[7,8]	-4	hSpCas9	negative selection	3293103
26472304	26472327		+	24336571	A375	viability after 14 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.4628558229155397	[10]	[19,9]	6	hSpCas9	negative selection	3293104
26472304	26472327	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	2.3983700929010188	[31,25]	[0,0]	8	hSpCas9	positive selection	3354018
26472359	26472382	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.11710626368755042	[150,130]	[0,0]	0	hSpCas9	positive selection	3354019
26477103	26477126	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.8041467504128121	[361,426]	[0,7]	4	hSpCas9	positive selection	3354020
26477006	26477029	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-1.1563017175783374	[340,340]	[0,0]	-7	hSpCas9	positive selection	3373236
26481724	26481747	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.7815927778464674	[262,262]	[0,0]	-5	hSpCas9	positive selection	3373237
26481738	26481761	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.4841407749553118	[213,213]	[0,0]	-3	hSpCas9	positive selection	3373238
26472305	26472328	22	+	26780180	HT29	viability (Avana library 4 designs)	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	1.68740786152476	[]	[]	6	hSpCas9	negative selection	3431392
26466218	26466241	22	+	26780180	HT29	viability (Avana library 4 designs)	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	1.39877963399667	[]	[]	5	hSpCas9	negative selection	3431393
26470785	26470808	22	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	1.28038000863443	[]	[]	5	hSpCas9	negative selection	3431394
26464770	26464793	22	-	26780180	HT29	viability (Avana library 4 designs)	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	0.684362560994594	[]	[]	2	hSpCas9	negative selection	3431395
26472305	26472328	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	0.207129356653338	[]	[]	0	hSpCas9	negative selection	3517018
26470785	26470808	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	1.19741113800869	[]	[]	1	hSpCas9	negative selection	3517019
26466218	26466241	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	2.51329541966065	[]	[]	4	hSpCas9	negative selection	3517020
26464770	26464793	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	0.491623596955028	[]	[]	0	hSpCas9	negative selection	3517021
26477064	26477087	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-6.52790190337522	[]	[]	-6	hSpCas9	negative selection	3517022
26465518	26465541	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGATAATCTGGACATTCGGGGG	HPS4	ENSG00000100099	-4.07179884580064	[]	[]	-5	hSpCas9	negative selection	3517023
26472305	26472328	22	+	26780180	A375	viability (Avana lentiGuide)	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	-3.30988396588194	[]	[]	-6	hSpCas9	negative selection	3625677
26470785	26470808	22	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-4.98761899554039	[]	[]	-8	hSpCas9	negative selection	3625678
26466218	26466241	22	+	26780180	A375	viability (Avana lentiGuide)	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	-2.47053526425018	[]	[]	-4	hSpCas9	negative selection	3625679
26464770	26464793	22	-	26780180	A375	viability (Avana lentiGuide)	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	-2.36758010794149	[]	[]	-4	hSpCas9	negative selection	3625680
26477064	26477087	22	+	26780180	A375	viability (Avana lentiGuide)	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-8.01018305392303	[]	[]	-9	hSpCas9	negative selection	3625681
26465518	26465541	22	+	26780180	A375	viability (Avana lentiGuide)	GGGATAATCTGGACATTCGGGGG	HPS4	ENSG00000100099	-2.36893321676803	[]	[]	-4	hSpCas9	negative selection	3625682
26472305	26472328	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	-0.06485745610314606	[5]	[5,4]	-1	hSpCas9	positive selection	3734336
26470785	26470808	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.0704488103395356	[3]	[5,2]	-1	hSpCas9	positive selection	3734337
26466218	26466241	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	0.016041474858459193	[4]	[5,3]	0	hSpCas9	positive selection	3734338
26464770	26464793	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	0.023170748693547988	[4]	[3,4]	0	hSpCas9	positive selection	3734339
26477064	26477087	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.6164731678139148	[4]	[3,1]	-7	hSpCas9	positive selection	3734340
26465518	26465541	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGATAATCTGGACATTCGGGGG	HPS4	ENSG00000100099	-0.22326827469539184	[5]	[5,3]	-4	hSpCas9	positive selection	3734341
26472305	26472328	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTTGGTCCAAGTTCCAGAGGG	HPS4	ENSG00000100099	0.2807744377567739	[5]	[5,5]	7	hSpCas9	positive selection	3842943
26470785	26470808	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.034018697678491916	[4]	[2,3]	0	hSpCas9	positive selection	3842944
26466218	26466241	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTTACCATGTTCCTGCGGGG	HPS4	ENSG00000100099	-0.021664276346244238	[4]	[5,2]	0	hSpCas9	positive selection	3842945
26464770	26464793	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCCCAGCACCATCCAAAGGG	HPS4	ENSG00000100099	0.15919227329382052	[4]	[4,4]	4	hSpCas9	positive selection	3842946
26477064	26477087	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.516659126190063	[4]	[5,4]	9	hSpCas9	positive selection	3842947
26465518	26465541	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGATAATCTGGACATTCGGGGG	HPS4	ENSG00000100099	0.18356132393270924	[6]	[6,6]	4	hSpCas9	positive selection	3842948
26477006	26477029	22	-	26780180	A375	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	0.609926762079729	[]	[]	2	hSpCas9	negative selection	3949000
26481724	26481747	22	+	26780180	A375	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.0661225524795758	[]	[]	-2	hSpCas9	negative selection	3949001
26481738	26481761	22	-	26780180	A375	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	1.42767488910968	[]	[]	7	hSpCas9	negative selection	3949002
26477103	26477126	22	+	26780180	A375	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.339499878039199	[]	[]	0	hSpCas9	negative selection	3949003
26472304	26472327	22	+	26780180	A375	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	1.00557900256339	[]	[]	4	hSpCas9	negative selection	3949004
26472359	26472382	22	+	26780180	A375	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.731693854143188	[]	[]	2	hSpCas9	negative selection	3949005
26477006	26477029	22	-	26780180	HT29	viability (GeCKOv2 library)	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	1.26914945567666	[]	[]	6	hSpCas9	negative selection	4056966
26481724	26481747	22	+	26780180	HT29	viability (GeCKOv2 library)	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.635063876465424	[]	[]	2	hSpCas9	negative selection	4056967
26481738	26481761	22	-	26780180	HT29	viability (GeCKOv2 library)	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.790838845989173	[]	[]	3	hSpCas9	negative selection	4056968
26477103	26477126	22	+	26780180	HT29	viability (GeCKOv2 library)	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.193172550919968	[]	[]	-5	hSpCas9	negative selection	4056969
26472304	26472327	22	+	26780180	HT29	viability (GeCKOv2 library)	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	1.01607242623866	[]	[]	4	hSpCas9	negative selection	4056970
26472359	26472382	22	+	26780180	HT29	viability (GeCKOv2 library)	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.361035053297976	[]	[]	1	hSpCas9	negative selection	4056971
26477006	26477029	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.509969431494286	[3]	[1,1]	-8	hSpCas9	positive selection	4143276
26481724	26481747	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.5063358072303702	[3]	[5,2]	9	hSpCas9	positive selection	4143277
26481738	26481761	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.10696989291218673	[3]	[1,2]	-2	hSpCas9	positive selection	4143278
26472304	26472327	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.7147793286703599	[3]	[1,0]	-9	hSpCas9	positive selection	4143279
26477006	26477029	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.303534480607215	[3]	[2,0,1,0]	-4	hSpCas9	positive selection	4207298
26481724	26481747	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	1.2273270187440306	[4]	[2,4,3,5]	8	hSpCas9	positive selection	4207299
26481738	26481761	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.8371271827246469	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4207300
26472304	26472327	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.7798225694373754	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4207301
26472304	26472327	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.0033768806877446933	[2]	[2,1]	0	hSpCas9	positive selection	4275731
26472359	26472382	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	-0.037250503630388614	[2]	[3,1]	0	hSpCas9	positive selection	4275732
26477103	26477126	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.46240241177523594	[4]	[4,4]	8	hSpCas9	positive selection	4275733
26477006	26477029	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2817995236317051	[4]	[3,1]	-5	hSpCas9	positive selection	4339991
26481724	26481747	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.1677634309042087	[3]	[4,2]	3	hSpCas9	positive selection	4339992
26481738	26481761	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.08747270560243596	[3]	[3,1]	1	hSpCas9	positive selection	4339993
26477113	26477135	22	+	27760321	OCIAML3	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.8987513281256836	[916,773]	[1019,1499]	9	hSpCas9	negative selection	4407930
26464670	26464692	22	+	27760321	OCIAML3	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.605518499495016	[595,496]	[486,856]	7	hSpCas9	negative selection	4407931
26470740	26470762	22	-	27760321	OCIAML3	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-9.029220862699638e-05	[1205,1323]	[836,1203]	0	hSpCas9	negative selection	4407932
26472823	26472845	22	+	27760321	OCIAML3	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.7799250841355412	[66,90]	[26,48]	-6	hSpCas9	negative selection	4407933
26472895	26472917	22	+	27760321	OCIAML3	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.30064275915539385	[782,619]	[506,885]	3	hSpCas9	negative selection	4407934
26477113	26477135	22	+	27760321	OCIAML2	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.7737692335159121	[916,773]	[1102,1246]	9	hSpCas9	negative selection	4491393
26464670	26464692	22	+	27760321	OCIAML2	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.14726377567346693	[595,496]	[465,515]	2	hSpCas9	negative selection	4491394
26470740	26470762	22	-	27760321	OCIAML2	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.38210314643866417	[1205,1323]	[1072,1698]	5	hSpCas9	negative selection	4491395
26472823	26472845	22	+	27760321	OCIAML2	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.6055316449228338	[66,90]	[49,32]	-6	hSpCas9	negative selection	4491396
26472895	26472917	22	+	27760321	OCIAML2	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.26497766355595986	[782,619]	[542,854]	3	hSpCas9	negative selection	4491397
26477113	26477135	22	+	27760321	MV411	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	1.2006262295761287	[916,773]	[1385,1114]	8	hSpCas9	negative selection	4574856
26464670	26464692	22	+	27760321	MV411	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.7374812057235651	[595,496]	[222,203]	-5	hSpCas9	negative selection	4574857
26470740	26470762	22	-	27760321	MV411	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.3968806780584244	[1205,1323]	[1263,870]	3	hSpCas9	negative selection	4574858
26472823	26472845	22	+	27760321	MV411	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-5.726651671263468	[66,90]	[0,0]	-9	hSpCas9	negative selection	4574859
26472895	26472917	22	+	27760321	MV411	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.19732650417309805	[782,619]	[349,793]	1	hSpCas9	negative selection	4574860
26477113	26477135	22	+	27760321	HL60	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.2494648953065175	[916,773]	[835,798]	3	hSpCas9	negative selection	4658319
26464670	26464692	22	+	27760321	HL60	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.05729954424930456	[595,496]	[468,382]	0	hSpCas9	negative selection	4658320
26470740	26470762	22	-	27760321	HL60	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.18621711371971306	[1205,1323]	[1219,1145]	2	hSpCas9	negative selection	4658321
26472823	26472845	22	+	27760321	HL60	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-2.1926581645191794	[66,90]	[8,19]	-9	hSpCas9	negative selection	4658322
26472895	26472917	22	+	27760321	HL60	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	-0.10173784293763188	[782,619]	[486,576]	-1	hSpCas9	negative selection	4658323
26477113	26477135	22	+	27760321	HT1080	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	1.278265599437735	[773,603]	[638,694]	7	hSpCas9	negative selection	4741782
26464670	26464692	22	+	27760321	HT1080	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	2.0292382985722215	[496,387]	[878,544]	9	hSpCas9	negative selection	4741783
26470740	26470762	22	-	27760321	HT1080	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.6306713619129816	[1323,1032]	[349,251]	-3	hSpCas9	negative selection	4741784
26472823	26472845	22	+	27760321	HT1080	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	4.0324747458692904	[90,70]	[475,584]	9	hSpCas9	negative selection	4741785
26472895	26472917	22	+	27760321	HT1080	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	-4.670092551088954	[619,483]	[0,16]	-8	hSpCas9	negative selection	4741786
26477113	26477135	22	+	27760321	HT29	viability after 7 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.33808918067819294	[773,603]	[1317,725,1334]	5	hSpCas9	negative selection	4825245
26464670	26464692	22	+	27760321	HT29	viability after 7 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.18798845477550807	[496,387]	[414,458,607]	-3	hSpCas9	negative selection	4825246
26470740	26470762	22	-	27760321	HT29	viability after 7 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.3509637080856116	[1323,1032]	[858,1202,1444]	-5	hSpCas9	negative selection	4825247
26472823	26472845	22	+	27760321	HT29	viability after 7 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.8560695928519344	[90,70]	[67,79,26]	-8	hSpCas9	negative selection	4825248
26472895	26472917	22	+	27760321	HT29	viability after 7 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.18597977964150203	[619,483]	[902,800,732]	3	hSpCas9	negative selection	4825249
26477113	26477135	22	+	27760321	HT29	viability after 25 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.8167836134578925	[773,603]	[1502,1136,1525]	8	hSpCas9	negative selection	4908708
26464670	26464692	22	+	27760321	HT29	viability after 25 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.026235391581878487	[496,387]	[405,632,450]	0	hSpCas9	negative selection	4908709
26470740	26470762	22	-	27760321	HT29	viability after 25 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.027219640661791722	[1323,1032]	[1202,1230,1728]	0	hSpCas9	negative selection	4908710
26472823	26472845	22	+	27760321	HT29	viability after 25 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.9394950134185152	[90,70]	[46,21,78]	-6	hSpCas9	negative selection	4908711
26472895	26472917	22	+	27760321	HT29	viability after 25 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.22203582470038818	[619,483]	[661,717,841]	2	hSpCas9	negative selection	4908712
26477113	26477135	22	+	27760321	HT29	viability after 22 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.7580058124771076	[773,603]	[1459,1121,1456]	8	hSpCas9	negative selection	4992171
26464670	26464692	22	+	27760321	HT29	viability after 22 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.4454613669493453	[496,387]	[391,910,795]	5	hSpCas9	negative selection	4992172
26470740	26470762	22	-	27760321	HT29	viability after 22 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.10775040799585889	[1323,1032]	[998,1339,1462]	-1	hSpCas9	negative selection	4992173
26472823	26472845	22	+	27760321	HT29	viability after 22 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-1.7227817770480738	[90,70]	[28,36,18]	-8	hSpCas9	negative selection	4992174
26472895	26472917	22	+	27760321	HT29	viability after 22 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.3246740713420567	[619,483]	[667,842,890]	3	hSpCas9	negative selection	4992175
26477113	26477135	22	+	27760321	HT29	viability after 19 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.7798522684950966	[773,603]	[1655,1224,1213]	7	hSpCas9	negative selection	5075634
26464670	26464692	22	+	27760321	HT29	viability after 19 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.2733606964096898	[496,387]	[604,673,556]	2	hSpCas9	negative selection	5075635
26470740	26470762	22	-	27760321	HT29	viability after 19 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.2933572117761245	[1323,1032]	[1519,1735,1682]	2	hSpCas9	negative selection	5075636
26472823	26472845	22	+	27760321	HT29	viability after 19 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.18030983853890703	[90,70]	[39,69,128]	-2	hSpCas9	negative selection	5075637
26472895	26472917	22	+	27760321	HT29	viability after 19 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.5695730037593022	[619,483]	[767,404,1593]	6	hSpCas9	negative selection	5075638
26477113	26477135	22	+	27760321	HT29	viability after 16 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.5031660273821699	[773,603]	[1051,1077,1143]	6	hSpCas9	negative selection	5159097
26464670	26464692	22	+	27760321	HT29	viability after 16 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.00572798801484925	[496,387]	[304,588,564]	0	hSpCas9	negative selection	5159098
26470740	26470762	22	-	27760321	HT29	viability after 16 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	0.08366884863089119	[1323,1032]	[1631,1189,1396]	0	hSpCas9	negative selection	5159099
26472823	26472845	22	+	27760321	HT29	viability after 16 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-0.8047905437871901	[90,70]	[60,31,63]	-6	hSpCas9	negative selection	5159100
26472895	26472917	22	+	27760321	HT29	viability after 16 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.29495258226651877	[619,483]	[956,786,546]	3	hSpCas9	negative selection	5159101
26477113	26477135	22	+	27760321	HT29	viability after 13 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.5977107173955394	[773,603]	[1326,1239,1069]	7	hSpCas9	negative selection	5242560
26464670	26464692	22	+	27760321	HT29	viability after 13 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.027685399632874974	[496,387]	[531,466,567]	0	hSpCas9	negative selection	5242561
26470740	26470762	22	-	27760321	HT29	viability after 13 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.2091466547088061	[1323,1032]	[1198,1170,1177]	-2	hSpCas9	negative selection	5242562
26472823	26472845	22	+	27760321	HT29	viability after 13 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-1.5550468945667393	[90,70]	[28,18,46]	-8	hSpCas9	negative selection	5242563
26472895	26472917	22	+	27760321	HT29	viability after 13 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.21135039374070463	[619,483]	[730,680,807]	2	hSpCas9	negative selection	5242564
26477113	26477135	22	+	27760321	HT29	viability after 10 days	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.6085021345041326	[773,603]	[1260,1482,1197]	8	hSpCas9	negative selection	5326023
26464670	26464692	22	+	27760321	HT29	viability after 10 days	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	-0.19669025198753076	[496,387]	[588,410,444]	-3	hSpCas9	negative selection	5326024
26470740	26470762	22	-	27760321	HT29	viability after 10 days	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.2724400545133798	[1323,1032]	[1192,1261,1200]	-3	hSpCas9	negative selection	5326025
26472823	26472845	22	+	27760321	HT29	viability after 10 days	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	-1.043579304326491	[90,70]	[36,70,39]	-8	hSpCas9	negative selection	5326026
26472895	26472917	22	+	27760321	HT29	viability after 10 days	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.387585685023104	[619,483]	[943,927,834]	5	hSpCas9	negative selection	5326027
26477113	26477135	22	+	27760321	MOLM13	viability	CAACTCCTGTTGGTCTAGCAGG	HPS4	ENSG00000100099	0.7924440282350671	[916,773]	[1055,624]	5	hSpCas9	negative selection	5409486
26464670	26464692	22	+	27760321	MOLM13	viability	ATCTGGACAAGCTTCGTCAGGG	HPS4	ENSG00000100099	0.3085738634295652	[595,496]	[315,434]	2	hSpCas9	negative selection	5409487
26470740	26470762	22	-	27760321	MOLM13	viability	GCTCGCCTCACATTCTCGCTGG	HPS4	ENSG00000100099	-0.6106093399531581	[1205,1323]	[722,255]	-4	hSpCas9	negative selection	5409488
26472823	26472845	22	+	27760321	MOLM13	viability	TACTTGTACCTCATAAGCTAGG	HPS4	ENSG00000100099	0.5775505894775466	[66,90]	[59,73]	4	hSpCas9	negative selection	5409489
26472895	26472917	22	+	27760321	MOLM13	viability	CCGCTTGCAGCTGACATCAGGG	HPS4	ENSG00000100099	0.6104912666060969	[782,619]	[418,754]	4	hSpCas9	negative selection	5409490
26483543	26483566	22	+	27661255	K562	viability	GGTGTCTGGCCCCAGCTCTACGG	HPS4	ENSG00000100099	0.1793225871723627	[143,160]	[148,127]	6	dCas9-KRAB	negative selection	5485474
26483785	26483808	22	-	27661255	K562	viability	GCGGGGCGGCGCGTGACCTAAGG	HPS4	ENSG00000100099	0.33755540827151914	[489,670]	[627,543]	9	dCas9-KRAB	negative selection	5485475
26472304	26472327	22	+	27260156	BXPC3	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.20583065029659195	[385]	[441,383,576,464]	4	hSpCas9	negative selection	5548191
26472359	26472382	22	+	27260156	BXPC3	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.34737389615587927	[433]	[567,505,527,725]	7	hSpCas9	negative selection	5548192
26477103	26477126	22	+	27260156	BXPC3	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.22694070294165414	[1329]	[1514,1458,1661,1921]	5	hSpCas9	negative selection	5548193
26477006	26477029	22	-	27260156	BXPC3	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.3153441643519953	[992]	[770,798,843,939]	-6	hSpCas9	negative selection	5612451
26481724	26481747	22	+	27260156	BXPC3	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.04016292662418597	[719]	[661,797,780,872]	0	hSpCas9	negative selection	5612452
26481738	26481761	22	-	27260156	BXPC3	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.27464773622216787	[469]	[430,746,541,670]	6	hSpCas9	negative selection	5612453
26472304	26472327	22	+	27260156	A673	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.0586822803474179	[385]	[559,335,485,410]	-1	hSpCas9	negative selection	5669442
26472359	26472382	22	+	27260156	A673	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.1630731982925266	[433]	[693,500,609,539]	4	hSpCas9	negative selection	5669443
26477103	26477126	22	+	27260156	A673	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.1304333989410198	[1329]	[1886,1863,1548,1700]	3	hSpCas9	negative selection	5669444
26477006	26477029	22	-	27260156	A673	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.5087250551201018	[992]	[868,783,836,866]	-8	hSpCas9	negative selection	5733702
26481724	26481747	22	+	27260156	A673	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.09938723728051968	[719]	[1060,739,873,1055]	2	hSpCas9	negative selection	5733703
26481738	26481761	22	-	27260156	A673	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.315611703083519	[469]	[664,660,703,778]	7	hSpCas9	negative selection	5733704
26472304	26472327	22	+	27260156	A375	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.11775899771921355	[385]	[480,394,393,390]	-2	hSpCas9	negative selection	5790693
26472359	26472382	22	+	27260156	A375	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.28638776736827426	[433]	[554,785,521,628]	4	hSpCas9	negative selection	5790694
26477103	26477126	22	+	27260156	A375	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.07034361559285429	[1329]	[1389,2041,1683,1475]	1	hSpCas9	negative selection	5790695
26477006	26477029	22	-	27260156	A375	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.27851211348202	[992]	[952,1009,996,877]	-4	hSpCas9	negative selection	5854953
26481724	26481747	22	+	27260156	A375	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.5274121281063568	[719]	[1229,1126,1447,1046]	7	hSpCas9	negative selection	5854954
26481738	26481761	22	-	27260156	A375	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.16415566740380183	[469]	[527,840,524,596]	2	hSpCas9	negative selection	5854955
26472304	26472327	22	+	27260156	COLO741	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.10315960943326324	[385]	[704,374,326]	-2	hSpCas9	negative selection	5911944
26472359	26472382	22	+	27260156	COLO741	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.3756438326817971	[433]	[829,645,691]	7	hSpCas9	negative selection	5911945
26477103	26477126	22	+	27260156	COLO741	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.2224174397710943	[1329]	[2285,1776,1910]	5	hSpCas9	negative selection	5911946
26477006	26477029	22	-	27260156	COLO741	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.39139482069074893	[992]	[1121,1052,753]	-7	hSpCas9	negative selection	5976204
26481724	26481747	22	+	27260156	COLO741	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.01287431461867472	[719]	[836,1079,862]	0	hSpCas9	negative selection	5976205
26481738	26481761	22	-	27260156	COLO741	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.43831861680694856	[469]	[887,750,806]	8	hSpCas9	negative selection	5976206
26472304	26472327	22	+	27260156	CAL120	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.37159951387480517	[385]	[436,341,344]	-5	hSpCas9	negative selection	6033195
26472359	26472382	22	+	27260156	CAL120	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.3920521559896509	[433]	[835,601,706]	6	hSpCas9	negative selection	6033196
26477103	26477126	22	+	27260156	CAL120	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.1871442239803094	[1329]	[2702,1846,1236]	2	hSpCas9	negative selection	6033197
26477006	26477029	22	-	27260156	CAL120	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2739861713979955	[992]	[1214,999,881]	-4	hSpCas9	negative selection	6097455
26481724	26481747	22	+	27260156	CAL120	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.05937655778728923	[719]	[1147,824,860]	0	hSpCas9	negative selection	6097456
26481738	26481761	22	-	27260156	CAL120	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.4568606265175944	[469]	[628,1017,735]	6	hSpCas9	negative selection	6097457
26472304	26472327	22	+	27260156	CADOES1	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.36281089224967655	[385]	[256,187,329,343]	-6	hSpCas9	negative selection	6154446
26472359	26472382	22	+	27260156	CADOES1	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.10089857498853794	[433]	[388,403,443,496]	1	hSpCas9	negative selection	6154447
26477103	26477126	22	+	27260156	CADOES1	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.21670702223488925	[1329]	[1215,1773,1199,1565]	3	hSpCas9	negative selection	6154448
26477006	26477029	22	-	27260156	CADOES1	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.22458031950185353	[992]	[850,676,568,1074]	-4	hSpCas9	negative selection	6218706
26481724	26481747	22	+	27260156	CADOES1	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.19858471237629816	[719]	[795,554,782,945]	3	hSpCas9	negative selection	6218707
26481738	26481761	22	-	27260156	CADOES1	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.11461081203938736	[469]	[468,554,504,359]	2	hSpCas9	negative selection	6218708
26472304	26472327	22	+	27260156	EWS502	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.3213464577347256	[385]	[389,291,385,226]	-5	hSpCas9	negative selection	6275697
26472359	26472382	22	+	27260156	EWS502	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.6796367564377096	[433]	[886,580,696,766]	9	hSpCas9	negative selection	6275698
26477103	26477126	22	+	27260156	EWS502	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.08946811824911749	[1329]	[1202,1347,1222,1544]	-2	hSpCas9	negative selection	6275699
26477006	26477029	22	-	27260156	EWS502	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.6105685870595492	[992]	[476,714,774,820]	-7	hSpCas9	negative selection	6339957
26481724	26481747	22	+	27260156	EWS502	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.16931188930694907	[719]	[827,922,823,851]	3	hSpCas9	negative selection	6339958
26481738	26481761	22	-	27260156	EWS502	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.057920698267603	[469]	[440,484,529,633]	1	hSpCas9	negative selection	6339959
26472304	26472327	22	+	27260156	EW8	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.03912784995276586	[385]	[367,225,388,294]	0	hSpCas9	negative selection	6396948
26472359	26472382	22	+	27260156	EW8	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.23462462540987372	[433]	[519,488,327,343]	4	hSpCas9	negative selection	6396949
26477103	26477126	22	+	27260156	EW8	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.11513555584250246	[1329]	[1044,1306,1169,1130]	2	hSpCas9	negative selection	6396950
26477006	26477029	22	-	27260156	EW8	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.14279344568998675	[992]	[659,616,847,759]	-3	hSpCas9	negative selection	6461208
26481724	26481747	22	+	27260156	EW8	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.11830303484360838	[719]	[823,630,507,610]	2	hSpCas9	negative selection	6461209
26481738	26481761	22	-	27260156	EW8	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.320419637823857	[469]	[630,465,406,425]	6	hSpCas9	negative selection	6461210
26472304	26472327	22	+	27260156	CORL105	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.007435850102321673	[385]	[345,507,605,375]	0	hSpCas9	negative selection	6518199
26472359	26472382	22	+	27260156	CORL105	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.14585586609656992	[433]	[520,563,738,450]	2	hSpCas9	negative selection	6518200
26477103	26477126	22	+	27260156	CORL105	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.2523726811507194	[1329]	[1945,1602,2014,1886]	5	hSpCas9	negative selection	6518201
26477006	26477029	22	-	27260156	CORL105	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.4038359527139401	[992]	[906,797,961,862]	-6	hSpCas9	negative selection	6582459
26481724	26481747	22	+	27260156	CORL105	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.24449268188231288	[719]	[929,1091,1174,820]	4	hSpCas9	negative selection	6582460
26481738	26481761	22	-	27260156	CORL105	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.4464802749878262	[469]	[538,970,784,697]	7	hSpCas9	negative selection	6582461
26472304	26472327	22	+	27260156	HS294T	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.4752689044723629	[385]	[89,122,90,129]	-6	hSpCas9	negative selection	6639450
26472359	26472382	22	+	27260156	HS294T	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.8533477259399	[433]	[282,378,305,230]	9	hSpCas9	negative selection	6639451
26477103	26477126	22	+	27260156	HS294T	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.06850083558485665	[1329]	[508,575,541,527]	0	hSpCas9	negative selection	6639452
26477006	26477029	22	-	27260156	HS294T	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.5961857579555823	[992]	[253,221,236,312]	-7	hSpCas9	negative selection	6703710
26481724	26481747	22	+	27260156	HS294T	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.08859909478778816	[719]	[254,262,266,261]	-1	hSpCas9	negative selection	6703711
26481738	26481761	22	-	27260156	HS294T	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.37861208562316806	[469]	[149,229,175,428]	5	hSpCas9	negative selection	6703712
26472304	26472327	22	+	27260156	HCC44	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.25254424052393576	[385]	[331,425,278,397]	-4	hSpCas9	negative selection	6760701
26472359	26472382	22	+	27260156	HCC44	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.5939474724590095	[433]	[594,835,911,620]	8	hSpCas9	negative selection	6760702
26477103	26477126	22	+	27260156	HCC44	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.15562405052798245	[1329]	[1877,1295,2119,1547]	2	hSpCas9	negative selection	6760703
26477006	26477029	22	-	27260156	HCC44	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2685035057661014	[992]	[974,936,843,952]	-4	hSpCas9	negative selection	6824961
26481724	26481747	22	+	27260156	HCC44	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.15904686923991007	[719]	[1009,870,879,878]	2	hSpCas9	negative selection	6824962
26481738	26481761	22	-	27260156	HCC44	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.06561260514991951	[469]	[532,432,405,828]	1	hSpCas9	negative selection	6824963
26472304	26472327	22	+	27260156	G402	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.06959622956031525	[385]	[470,335,626,526]	0	hSpCas9	negative selection	6881952
26472359	26472382	22	+	27260156	G402	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.5549073912366753	[433]	[735,747,1091,536]	7	hSpCas9	negative selection	6881953
26477103	26477126	22	+	27260156	G402	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.08664909935985965	[1329]	[2007,1466,2099,1355]	1	hSpCas9	negative selection	6881954
26477006	26477029	22	-	27260156	G402	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	0.21477693459417546	[992]	[1177,1169,1616,1597]	2	hSpCas9	negative selection	6946212
26481724	26481747	22	+	27260156	G402	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.4113747261846985	[719]	[1544,1050,788,1323]	5	hSpCas9	negative selection	6946213
26481738	26481761	22	-	27260156	G402	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.8085377110363928	[469]	[452,1317,1421,770]	8	hSpCas9	negative selection	6946214
26472304	26472327	22	+	27260156	L33	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.08308310550098491	[385]	[355,182,206,325]	-2	hSpCas9	negative selection	7003203
26472359	26472382	22	+	27260156	L33	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.4173165603344389	[433]	[540,182,521,502]	8	hSpCas9	negative selection	7003204
26477103	26477126	22	+	27260156	L33	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.07551199020291022	[1329]	[1306,558,936,1445]	1	hSpCas9	negative selection	7003205
26477006	26477029	22	-	27260156	L33	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.27355520815990153	[992]	[753,295,516,986]	-6	hSpCas9	negative selection	7067463
26481724	26481747	22	+	27260156	L33	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.04281334441177065	[719]	[643,332,481,574]	-1	hSpCas9	negative selection	7067464
26481738	26481761	22	-	27260156	L33	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.01372549645744884	[469]	[487,148,383,435]	0	hSpCas9	negative selection	7067465
26472304	26472327	22	+	27260156	K562	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.009756121991957134	[385]	[141,466,523,229]	0	hSpCas9	negative selection	7124454
26472359	26472382	22	+	27260156	K562	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.3380939180535735	[433]	[787,547,355,302]	4	hSpCas9	negative selection	7124455
26477103	26477126	22	+	27260156	K562	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.1608778340672652	[1329]	[1761,1061,961,1488]	2	hSpCas9	negative selection	7124456
26477006	26477029	22	-	27260156	K562	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.03231174768332323	[992]	[559,1388,907,617]	0	hSpCas9	negative selection	7188714
26481724	26481747	22	+	27260156	K562	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.16865203055403338	[719]	[894,510,347,543]	-2	hSpCas9	negative selection	7188715
26481738	26481761	22	-	27260156	K562	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.02299563284109896	[469]	[573,472,404,273]	0	hSpCas9	negative selection	7188716
26472304	26472327	22	+	27260156	HT29	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.0022698453188219614	[385]	[386,759,369,382]	0	hSpCas9	negative selection	7245705
26472359	26472382	22	+	27260156	HT29	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.35873701617348597	[433]	[581,959,569,613]	7	hSpCas9	negative selection	7245706
26477103	26477126	22	+	27260156	HT29	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.16943086811622043	[1329]	[2192,1760,1667,1678]	3	hSpCas9	negative selection	7245707
26477006	26477029	22	-	27260156	HT29	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.17780365266122455	[992]	[871,1363,1001,1036]	-4	hSpCas9	negative selection	7309965
26481724	26481747	22	+	27260156	HT29	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.22798171440424408	[719]	[1258,1083,1098,712]	4	hSpCas9	negative selection	7309966
26481738	26481761	22	-	27260156	HT29	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.22064478900562212	[469]	[727,881,535,549]	4	hSpCas9	negative selection	7309967
26472304	26472327	22	+	27260156	MHHES1	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.11933609886039931	[385]	[397,361,292,507]	-2	hSpCas9	negative selection	7366956
26472359	26472382	22	+	27260156	MHHES1	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.27446680607059587	[433]	[620,540,562,617]	5	hSpCas9	negative selection	7366957
26477103	26477126	22	+	27260156	MHHES1	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.06344598260084822	[1329]	[1744,1632,1720,1233]	1	hSpCas9	negative selection	7366958
26477006	26477029	22	-	27260156	MHHES1	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.3451603924415796	[992]	[946,912,954,732]	-6	hSpCas9	negative selection	7431216
26481724	26481747	22	+	27260156	MHHES1	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.05021145891423762	[719]	[898,1284,702,567]	0	hSpCas9	negative selection	7431217
26481738	26481761	22	-	27260156	MHHES1	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.3028842958665845	[469]	[593,818,601,602]	5	hSpCas9	negative selection	7431218
26472304	26472327	22	+	27260156	MEWO	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.0375153468510509	[385]	[505,219,359]	-1	hSpCas9	negative selection	7488207
26472359	26472382	22	+	27260156	MEWO	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	-0.006587205494868478	[433]	[497,329,402]	0	hSpCas9	negative selection	7488208
26477103	26477126	22	+	27260156	MEWO	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.31707185876824173	[1329]	[1918,1457,1344]	6	hSpCas9	negative selection	7488209
26477006	26477029	22	-	27260156	MEWO	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.29601657354281297	[992]	[998,718,598]	-6	hSpCas9	negative selection	7552467
26481724	26481747	22	+	27260156	MEWO	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.05636577919613994	[719]	[908,613,618]	1	hSpCas9	negative selection	7552468
26481738	26481761	22	-	27260156	MEWO	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.2895197389081355	[469]	[628,520,479]	6	hSpCas9	negative selection	7552469
26472304	26472327	22	+	27260156	LNCAPCLONEFGC	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.12446249237251703	[385]	[349,355,470,362]	2	hSpCas9	negative selection	7609458
26472359	26472382	22	+	27260156	LNCAPCLONEFGC	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.32343561691161893	[433]	[377,499,625,484]	5	hSpCas9	negative selection	7609459
26477103	26477126	22	+	27260156	LNCAPCLONEFGC	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.267635993427336	[1329]	[1267,1251,1745,1594]	4	hSpCas9	negative selection	7609460
26477006	26477029	22	-	27260156	LNCAPCLONEFGC	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.3991158440942919	[992]	[727,513,794,717]	-6	hSpCas9	negative selection	7673718
26481724	26481747	22	+	27260156	LNCAPCLONEFGC	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.2818898472326318	[719]	[696,731,1121,674]	4	hSpCas9	negative selection	7673719
26481738	26481761	22	-	27260156	LNCAPCLONEFGC	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.4507441041101944	[469]	[578,596,613,540]	7	hSpCas9	negative selection	7673720
26472304	26472327	22	+	27260156	PANC0327	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.08691426517760603	[385]	[294,306,324,363]	-1	hSpCas9	negative selection	7730709
26472359	26472382	22	+	27260156	PANC0327	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.8530115376674767	[433]	[403,413,1403,576]	9	hSpCas9	negative selection	7730710
26477103	26477126	22	+	27260156	PANC0327	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.5111158062296816	[1329]	[1089,751,748,755]	-6	hSpCas9	negative selection	7730711
26477006	26477029	22	-	27260156	PANC0327	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2969268247451944	[992]	[855,659,862,511]	-4	hSpCas9	negative selection	7794969
26481724	26481747	22	+	27260156	PANC0327	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.10953240302627787	[719]	[783,489,552,572]	-2	hSpCas9	negative selection	7794970
26481738	26481761	22	-	27260156	PANC0327	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.07885496036517736	[469]	[737,257,394,235]	-1	hSpCas9	negative selection	7794971
26472304	26472327	22	+	27260156	NCIH2009	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.05373987535579339	[385]	[780,383,446]	0	hSpCas9	negative selection	7851960
26472359	26472382	22	+	27260156	NCIH2009	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.5229765993936155	[433]	[843,706,1058]	7	hSpCas9	negative selection	7851961
26477103	26477126	22	+	27260156	NCIH2009	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.10815536896823863	[1329]	[1738,1726,1705]	-1	hSpCas9	negative selection	7851962
26477006	26477029	22	-	27260156	NCIH2009	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.07364057385082456	[992]	[1354,1098,1509]	-1	hSpCas9	negative selection	7916220
26481724	26481747	22	+	27260156	NCIH2009	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.17815519025660798	[719]	[1544,1192,753]	2	hSpCas9	negative selection	7916221
26481738	26481761	22	-	27260156	NCIH2009	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.21480810784928048	[469]	[962,744,616]	3	hSpCas9	negative selection	7916222
26472304	26472327	22	+	27260156	NCIH1373	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.11289358406659195	[385]	[988,149,151,113]	-1	hSpCas9	negative selection	7973211
26472359	26472382	22	+	27260156	NCIH1373	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.7331355733949982	[433]	[1220,783,778,129]	7	hSpCas9	negative selection	7973212
26477103	26477126	22	+	27260156	NCIH1373	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.04540534168290877	[1329]	[2240,1045,1271,464]	0	hSpCas9	negative selection	7973213
26477006	26477029	22	-	27260156	NCIH1373	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	0.1174073001173288	[992]	[1288,590,1243,476]	1	hSpCas9	negative selection	8037471
26481724	26481747	22	+	27260156	NCIH1373	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.6000285317983522	[719]	[1064,767,1272,483]	6	hSpCas9	negative selection	8037472
26481738	26481761	22	-	27260156	NCIH1373	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.09535147167754539	[469]	[345,297,650,178]	-1	hSpCas9	negative selection	8037473
26472304	26472327	22	+	27260156	PATU8902	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.2082645571969876	[385]	[904,485,100,452]	-2	hSpCas9	negative selection	8094462
26472359	26472382	22	+	27260156	PATU8902	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	1.4557867268789235	[433]	[1450,1550,1727,1901]	9	hSpCas9	negative selection	8094463
26477103	26477126	22	+	27260156	PATU8902	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.138074527797436	[1329]	[2189,1533,1570,3084]	1	hSpCas9	negative selection	8094464
26477006	26477029	22	-	27260156	PATU8902	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.39876703778625355	[992]	[1284,868,903,1178]	-4	hSpCas9	negative selection	8158722
26481724	26481747	22	+	27260156	PATU8902	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.8190590490651617	[719]	[1354,1704,1525,2649]	8	hSpCas9	negative selection	8158723
26481738	26481761	22	-	27260156	PATU8902	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.6754392523172402	[469]	[1422,409,1098,1243]	7	hSpCas9	negative selection	8158724
26472304	26472327	22	+	27260156	PANC1	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.1733815503325988	[385]	[236,499,536,263]	2	hSpCas9	negative selection	8215713
26472359	26472382	22	+	27260156	PANC1	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.38491156698037154	[433]	[358,704,454,469]	6	hSpCas9	negative selection	8215714
26477103	26477126	22	+	27260156	PANC1	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.15318961981507861	[1329]	[1545,1459,1189,949]	2	hSpCas9	negative selection	8215715
26477006	26477029	22	-	27260156	PANC1	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2183640734514095	[992]	[845,824,525,736]	-4	hSpCas9	negative selection	8279973
26481724	26481747	22	+	27260156	PANC1	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.28051719685310383	[719]	[709,713,977,608]	4	hSpCas9	negative selection	8279974
26481738	26481761	22	-	27260156	PANC1	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.31840102454337527	[469]	[440,688,530,400]	5	hSpCas9	negative selection	8279975
26472304	26472327	22	+	27260156	PANC0813	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.3681453867353436	[385]	[449,419,261,284]	-5	hSpCas9	negative selection	8336964
26472359	26472382	22	+	27260156	PANC0813	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.32806196265642734	[433]	[819,701,441,611]	5	hSpCas9	negative selection	8336965
26477103	26477126	22	+	27260156	PANC0813	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.06425101464516336	[1329]	[1601,1506,1503,1377]	-1	hSpCas9	negative selection	8336966
26477006	26477029	22	-	27260156	PANC0813	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.12941972485095266	[992]	[1043,1378,823,1015]	-2	hSpCas9	negative selection	8401224
26481724	26481747	22	+	27260156	PANC0813	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.15403174826282717	[719]	[1029,1076,658,999]	2	hSpCas9	negative selection	8401225
26481738	26481761	22	-	27260156	PANC0813	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	-0.14347585823762427	[469]	[659,425,530,401]	-2	hSpCas9	negative selection	8401226
26472304	26472327	22	+	27260156	RDES	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.6905149090447983	[385]	[233,356,274,216]	-8	hSpCas9	negative selection	8458215
26472359	26472382	22	+	27260156	RDES	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.38490456673124807	[433]	[628,700,559,697]	6	hSpCas9	negative selection	8458216
26477103	26477126	22	+	27260156	RDES	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.07970363619903598	[1329]	[1241,1512,1941,1861]	1	hSpCas9	negative selection	8458217
26477006	26477029	22	-	27260156	RDES	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.41287536423184146	[992]	[722,878,897,945]	-6	hSpCas9	negative selection	8522475
26481724	26481747	22	+	27260156	RDES	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.13959631908144865	[719]	[818,758,958,1156]	2	hSpCas9	negative selection	8522476
26481738	26481761	22	-	27260156	RDES	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.32994275521184674	[469]	[574,608,753,810]	5	hSpCas9	negative selection	8522477
26472304	26472327	22	+	27260156	PC3	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.13988744085426374	[385]	[237,353,592,316]	-3	hSpCas9	negative selection	8579466
26472359	26472382	22	+	27260156	PC3	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.24504535793156518	[433]	[417,450,676,551]	5	hSpCas9	negative selection	8579467
26477103	26477126	22	+	27260156	PC3	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.2390853784361877	[1329]	[1116,1150,2970,1621]	5	hSpCas9	negative selection	8579468
26477006	26477029	22	-	27260156	PC3	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.20117637544881606	[992]	[635,933,1081,873]	-4	hSpCas9	negative selection	8643726
26481724	26481747	22	+	27260156	PC3	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.06597393101083959	[719]	[429,633,1039,830]	-1	hSpCas9	negative selection	8643727
26481738	26481761	22	-	27260156	PC3	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.04547666689604171	[469]	[297,514,921,398]	1	hSpCas9	negative selection	8643728
26472304	26472327	22	+	27260156	PATU8988T	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.40401587665361416	[385]	[359,297,202,267]	-6	hSpCas9	negative selection	8700717
26472359	26472382	22	+	27260156	PATU8988T	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.5821218620255001	[433]	[490,639,522,879]	8	hSpCas9	negative selection	8700718
26477103	26477126	22	+	27260156	PATU8988T	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	-0.21937701208317617	[1329]	[953,1403,866,1231]	-4	hSpCas9	negative selection	8700719
26477006	26477029	22	-	27260156	PATU8988T	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.6178837330883531	[992]	[537,633,611,725]	-7	hSpCas9	negative selection	8764977
26481724	26481747	22	+	27260156	PATU8988T	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.22601868269314251	[719]	[855,1074,714,618]	4	hSpCas9	negative selection	8764978
26481738	26481761	22	-	27260156	PATU8988T	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.10638055039012974	[469]	[396,495,690,358]	1	hSpCas9	negative selection	8764979
26472304	26472327	22	+	27260156	T47D	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.0062849415886748194	[385]	[519,418,420,449]	0	hSpCas9	negative selection	8821968
26472359	26472382	22	+	27260156	T47D	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.2804059259284517	[433]	[551,564,550,798]	6	hSpCas9	negative selection	8821969
26477103	26477126	22	+	27260156	T47D	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.22974121599644026	[1329]	[1712,1833,1792,1928]	5	hSpCas9	negative selection	8821970
26477006	26477029	22	-	27260156	T47D	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.2582899376174832	[992]	[1062,895,915,1001]	-5	hSpCas9	negative selection	8886228
26481724	26481747	22	+	27260156	T47D	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.18722328215409423	[719]	[921,806,952,1156]	4	hSpCas9	negative selection	8886229
26481738	26481761	22	-	27260156	T47D	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.12489140808773806	[469]	[714,545,574,555]	2	hSpCas9	negative selection	8886230
26472304	26472327	22	+	27260156	SU8686	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.02513219591323318	[385]	[321,346,378,544]	0	hSpCas9	negative selection	8943219
26472359	26472382	22	+	27260156	SU8686	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.41522356769731905	[433]	[483,561,528,755]	7	hSpCas9	negative selection	8943220
26477103	26477126	22	+	27260156	SU8686	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.03467536451765163	[1329]	[1192,1160,1562,1557]	0	hSpCas9	negative selection	8943221
26477006	26477029	22	-	27260156	SU8686	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.13615665935906307	[992]	[823,756,737,1353]	-2	hSpCas9	negative selection	9007479
26481724	26481747	22	+	27260156	SU8686	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.07832507430353186	[719]	[601,662,888,913]	1	hSpCas9	negative selection	9007480
26481738	26481761	22	-	27260156	SU8686	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.09644789239115749	[469]	[473,493,508,518]	1	hSpCas9	negative selection	9007481
26472304	26472327	22	+	27260156	SKES1	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.24834750346126178	[385]	[507,287,236,286]	-5	hSpCas9	negative selection	9064470
26472359	26472382	22	+	27260156	SKES1	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.21204622633136672	[433]	[463,646,513,399]	4	hSpCas9	negative selection	9064471
26477103	26477126	22	+	27260156	SKES1	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.05467616764821681	[1329]	[1593,1478,1381,1115]	1	hSpCas9	negative selection	9064472
26477006	26477029	22	-	27260156	SKES1	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.4510085223574175	[992]	[784,745,545,815]	-7	hSpCas9	negative selection	9128730
26481724	26481747	22	+	27260156	SKES1	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.03402349300582974	[719]	[752,699,860,628]	0	hSpCas9	negative selection	9128731
26481738	26481761	22	-	27260156	SKES1	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.22431413912151857	[469]	[676,658,395,492]	5	hSpCas9	negative selection	9128732
26472304	26472327	22	+	27260156	TOV112D	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.1332709890851559	[385]	[326,454,281,367]	-3	hSpCas9	negative selection	9185721
26472359	26472382	22	+	27260156	TOV112D	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.24993280254795336	[433]	[635,528,552,365]	5	hSpCas9	negative selection	9185722
26477103	26477126	22	+	27260156	TOV112D	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.28837801601425994	[1329]	[1534,1942,1411,1682]	5	hSpCas9	negative selection	9185723
26477006	26477029	22	-	27260156	TOV112D	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.5429810464563672	[992]	[871,757,603,533]	-8	hSpCas9	negative selection	9249981
26481724	26481747	22	+	27260156	TOV112D	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.08889608694054618	[719]	[504,952,552,750]	-2	hSpCas9	negative selection	9249982
26481738	26481761	22	-	27260156	TOV112D	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.0005636033575608366	[469]	[309,545,531,498]	0	hSpCas9	negative selection	9249983
26472304	26472327	22	+	27260156	TC71	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.07292205999682708	[385]	[375,482,474,404]	1	hSpCas9	negative selection	9306972
26472359	26472382	22	+	27260156	TC71	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.22968817206072056	[433]	[589,424,494,680]	5	hSpCas9	negative selection	9306973
26477103	26477126	22	+	27260156	TC71	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.12344614288197686	[1329]	[1581,1476,1586,1564]	3	hSpCas9	negative selection	9306974
26477006	26477029	22	-	27260156	TC71	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.36747254879106683	[992]	[853,751,799,898]	-7	hSpCas9	negative selection	9371232
26481724	26481747	22	+	27260156	TC71	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	-0.007002314878746474	[719]	[754,780,752,784]	0	hSpCas9	negative selection	9371233
26481738	26481761	22	-	27260156	TC71	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.2521673412799908	[469]	[451,596,654,703]	6	hSpCas9	negative selection	9371234
26472304	26472327	22	+	27260156	TC32	viability	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.10816594651176004	[385]	[240,232,506,432]	-2	hSpCas9	negative selection	9428223
26472359	26472382	22	+	27260156	TC32	viability	TTTCAGAATTTGCTCGATGAAGG	HPS4	ENSG00000100099	0.31761610882809005	[433]	[555,325,644,565]	5	hSpCas9	negative selection	9428224
26477103	26477126	22	+	27260156	TC32	viability	GTCCACAAAGCAACTCCTGTTGG	HPS4	ENSG00000100099	0.07445209919625961	[1329]	[992,1072,1878,1481]	1	hSpCas9	negative selection	9428225
26477006	26477029	22	-	27260156	TC32	viability	AAGTTTGCCATAAAAGTTGATGG	HPS4	ENSG00000100099	-0.23027355546269657	[992]	[742,682,1041,753]	-4	hSpCas9	negative selection	9492483
26481724	26481747	22	+	27260156	TC32	viability	CGAGGCTGACTTTGCCTCTGTGG	HPS4	ENSG00000100099	0.12553818873336575	[719]	[788,648,747,747]	2	hSpCas9	negative selection	9492484
26481738	26481761	22	-	27260156	TC32	viability	GGCCACCTCTACCTCCACAGAGG	HPS4	ENSG00000100099	0.1897201485067215	[469]	[501,418,648,468]	3	hSpCas9	negative selection	9492485
26470785	26470808	22	+	27869803	HPAFII	viability after 27 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.23923564397292002	[327]	[340,88,NaN]	2	hSpCas9	negative selection	9580185
26470881	26470904	22	+	27869803	HPAFII	viability after 27 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.05311133645956234	[152]	[107,62,NaN]	0	hSpCas9	negative selection	9580186
26472304	26472327	22	+	27869803	HPAFII	viability after 27 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.2795572572112839	[190]	[49,109,NaN]	-2	hSpCas9	negative selection	9580187
26472830	26472853	22	+	27869803	HPAFII	viability after 27 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.9035349804090524	[318]	[322,305,NaN]	7	hSpCas9	negative selection	9580188
26476977	26477000	22	+	27869803	HPAFII	viability after 27 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.24766507364890306	[298]	[292,97,NaN]	2	hSpCas9	negative selection	9580189
26479308	26479331	22	-	27869803	HPAFII	viability after 27 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.9294799872911848	[137]	[147,129,NaN]	7	hSpCas9	negative selection	9580190
26470785	26470808	22	+	27869803	HPAFII	viability after 15 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.18050966158705523	[327]	[516,182,NaN]	-2	hSpCas9	negative selection	9662634
26470881	26470904	22	+	27869803	HPAFII	viability after 15 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.49513489146500245	[152]	[351,156,NaN]	5	hSpCas9	negative selection	9662635
26472304	26472327	22	+	27869803	HPAFII	viability after 15 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.4711060899982069	[190]	[181,126,NaN]	-5	hSpCas9	negative selection	9662636
26472830	26472853	22	+	27869803	HPAFII	viability after 15 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	1.055302066128867	[318]	[939,570,NaN]	9	hSpCas9	negative selection	9662637
26476977	26477000	22	+	27869803	HPAFII	viability after 15 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.4843884649677674	[298]	[710,286,NaN]	5	hSpCas9	negative selection	9662638
26479308	26479331	22	-	27869803	HPAFII	viability after 15 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.48164069428746253	[137]	[314,139,NaN]	5	hSpCas9	negative selection	9662639
26470785	26470808	22	+	27869803	ASPC1	viability after 36 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.5076968203362048	[841]	[224,252,154]	-5	hSpCas9	negative selection	9745083
26470881	26470904	22	+	27869803	ASPC1	viability after 36 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.1169626022993484	[394]	[47,313,32]	-1	hSpCas9	negative selection	9745084
26472304	26472327	22	+	27869803	ASPC1	viability after 36 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	0.36894069099647475	[284]	[122,266,20]	3	hSpCas9	negative selection	9745085
26472830	26472853	22	+	27869803	ASPC1	viability after 36 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.5653555513367379	[740]	[557,447,203]	5	hSpCas9	negative selection	9745086
26476977	26477000	22	+	27869803	ASPC1	viability after 36 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.621237031455658	[654]	[890,121,151]	6	hSpCas9	negative selection	9745087
26479308	26479331	22	-	27869803	ASPC1	viability after 36 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.7959251334207392	[180]	[143,103,88]	7	hSpCas9	negative selection	9745088
26470785	26470808	22	+	27869803	PATU8988S	viability after 35 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.20594891863031983	[847]	[366,420,NaN]	2	hSpCas9	negative selection	9827532
26470881	26470904	22	+	27869803	PATU8988S	viability after 35 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	-0.3267830873939951	[340]	[109,108,NaN]	-3	hSpCas9	negative selection	9827533
26472304	26472327	22	+	27869803	PATU8988S	viability after 35 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.21233316531495938	[209]	[73,71,NaN]	-2	hSpCas9	negative selection	9827534
26472830	26472853	22	+	27869803	PATU8988S	viability after 35 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.49544496499461443	[634]	[377,342,NaN]	5	hSpCas9	negative selection	9827535
26476977	26477000	22	+	27869803	PATU8988S	viability after 35 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.0224792378122447	[679]	[352,202,NaN]	0	hSpCas9	negative selection	9827536
26479308	26479331	22	-	27869803	PATU8988S	viability after 35 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	1.708669153780223	[190]	[223,278,NaN]	9	hSpCas9	negative selection	9827537
26470785	26470808	22	+	27869803	PATU8988S	viability after 31 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.0017472049866540384	[847]	[261,435,NaN]	0	hSpCas9	negative selection	9909981
26470881	26470904	22	+	27869803	PATU8988S	viability after 31 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.05889556084328085	[340]	[127,158,NaN]	0	hSpCas9	negative selection	9909982
26472304	26472327	22	+	27869803	PATU8988S	viability after 31 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.3663167286954061	[209]	[60,69,NaN]	-4	hSpCas9	negative selection	9909983
26472830	26472853	22	+	27869803	PATU8988S	viability after 31 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	0.19840078318505322	[634]	[341,224,NaN]	2	hSpCas9	negative selection	9909984
26476977	26477000	22	+	27869803	PATU8988S	viability after 31 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	-0.0026953737213005757	[679]	[267,273,NaN]	0	hSpCas9	negative selection	9909985
26479308	26479331	22	-	27869803	PATU8988S	viability after 31 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	1.3225567492004067	[190]	[204,171,NaN]	9	hSpCas9	negative selection	9909986
26470785	26470808	22	+	27869803	HPAFII	viability after 35 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.8387404655507016	[327]	[486,82,NaN]	5	hSpCas9	negative selection	9992430
26470881	26470904	22	+	27869803	HPAFII	viability after 35 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.6597317862770431	[152]	[143,97,NaN]	4	hSpCas9	negative selection	9992431
26472304	26472327	22	+	27869803	HPAFII	viability after 35 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.5932924463902148	[190]	[9,124,NaN]	-4	hSpCas9	negative selection	9992432
26472830	26472853	22	+	27869803	HPAFII	viability after 35 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	1.461504296739558	[318]	[519,359,NaN]	8	hSpCas9	negative selection	9992433
26476977	26477000	22	+	27869803	HPAFII	viability after 35 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.5870950763931622	[298]	[296,148,NaN]	4	hSpCas9	negative selection	9992434
26479308	26479331	22	-	27869803	HPAFII	viability after 35 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	0.6664379625918763	[137]	[108,112,NaN]	4	hSpCas9	negative selection	9992435
26470785	26470808	22	+	27869803	HPAFII	viability after 31 days	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.5825129862609231	[327]	[412,125,NaN]	4	hSpCas9	negative selection	10074879
26470881	26470904	22	+	27869803	HPAFII	viability after 31 days	AAAGGGTTGTACAGAACAGCTGG	HPS4	ENSG00000100099	0.5931099096254228	[152]	[118,140,NaN]	4	hSpCas9	negative selection	10074880
26472304	26472327	22	+	27869803	HPAFII	viability after 31 days	TAGTTTGGTCCAAGTTCCAGAGG	HPS4	ENSG00000100099	-0.40077672007559284	[190]	[51,112,NaN]	-3	hSpCas9	negative selection	10074881
26472830	26472853	22	+	27869803	HPAFII	viability after 31 days	ACCTCATAAGCTAGGGAAACAGG	HPS4	ENSG00000100099	1.4833083754964658	[318]	[467,535,NaN]	9	hSpCas9	negative selection	10074882
26476977	26477000	22	+	27869803	HPAFII	viability after 31 days	CTGCCATTCAACTTACCCAAAGG	HPS4	ENSG00000100099	0.29571997255472876	[298]	[305,96,NaN]	2	hSpCas9	negative selection	10074883
26479308	26479331	22	-	27869803	HPAFII	viability after 31 days	GGTTCCAAGGTAAAGGAAGAAGG	HPS4	ENSG00000100099	1.0690158149043543	[137]	[217,101,NaN]	7	hSpCas9	negative selection	10074884
26457927	26457950	22	+	28162770	P31FUJ	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.5795707924098501	[40]	[71]	6	hSpCas9	negative selection	10171020
26464330	26464353	22	+	28162770	P31FUJ	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.03849981740301578	[86]	[104]	0	hSpCas9	negative selection	10171021
26479290	26479313	22	-	28162770	P31FUJ	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.31263193212014	[147]	[215]	3	hSpCas9	negative selection	10171022
26477064	26477087	22	+	28162770	P31FUJ	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	1.1534763018830416	[56]	[148]	9	hSpCas9	negative selection	10171023
26470785	26470808	22	+	28162770	P31FUJ	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.8684811314228028	[329]	[707]	8	hSpCas9	negative selection	10171024
26465468	26465491	22	-	28162770	P31FUJ	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.6175617166844877	[202]	[365]	7	hSpCas9	negative selection	10171025
26464767	26464790	22	-	28162770	P31FUJ	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.44782540560201556	[281]	[451]	5	hSpCas9	negative selection	10171026
26464590	26464613	22	-	28162770	P31FUJ	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.0927542443066821	[205]	[226]	-1	hSpCas9	negative selection	10171027
26464574	26464597	22	+	28162770	P31FUJ	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.2552987570541887	[384]	[539]	2	hSpCas9	negative selection	10171028
26464460	26464483	22	+	28162770	P31FUJ	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.29625155515612145	[227]	[328]	3	hSpCas9	negative selection	10171029
26457927	26457950	22	+	28162770	TF1	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10340386
26464330	26464353	22	+	28162770	TF1	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10340387
26479290	26479313	22	-	28162770	TF1	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10340388
26477064	26477087	22	+	28162770	TF1	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10340389
26470785	26470808	22	+	28162770	TF1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	NaN	[NaN]	[398]	1	hSpCas9	negative selection	10340390
26465468	26465491	22	-	28162770	TF1	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10340391
26464767	26464790	22	-	28162770	TF1	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	NaN	[NaN]	[246]	1	hSpCas9	negative selection	10340392
26464590	26464613	22	-	28162770	TF1	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10340393
26464574	26464597	22	+	28162770	TF1	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	NaN	[NaN]	[561]	1	hSpCas9	negative selection	10340394
26464460	26464483	22	+	28162770	TF1	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10340395
26457927	26457950	22	+	28162770	SKM1	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.8560702070906323	[14]	[47]	7	hSpCas9	negative selection	10509752
26464330	26464353	22	+	28162770	SKM1	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.2065674541747653	[24]	[50]	2	hSpCas9	negative selection	10509753
26479290	26479313	22	-	28162770	SKM1	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.35553648753018197	[41]	[94]	3	hSpCas9	negative selection	10509754
26477064	26477087	22	+	28162770	SKM1	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.43867305847049964	[22]	[29]	-4	hSpCas9	negative selection	10509755
26470785	26470808	22	+	28162770	SKM1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.948283969344227	[106]	[364]	8	hSpCas9	negative selection	10509756
26465468	26465491	22	-	28162770	SKM1	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.10644504095296031	[61]	[117]	1	hSpCas9	negative selection	10509757
26464767	26464790	22	-	28162770	SKM1	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.5378942470643774	[59]	[153]	5	hSpCas9	negative selection	10509758
26464590	26464613	22	-	28162770	SKM1	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.33915309379257486	[54]	[122]	3	hSpCas9	negative selection	10509759
26464574	26464597	22	+	28162770	SKM1	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.2691461900361897	[68]	[146]	2	hSpCas9	negative selection	10509760
26464460	26464483	22	+	28162770	SKM1	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.6457772633288117	[46]	[129]	6	hSpCas9	negative selection	10509761
26457927	26457950	22	+	28162770	SKM1	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.8560702070906323	[14]	[47]	7	hSpCas9	negative selection	10679118
26464330	26464353	22	+	28162770	SKM1	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.2065674541747653	[24]	[50]	2	hSpCas9	negative selection	10679119
26479290	26479313	22	-	28162770	SKM1	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.35553648753018197	[41]	[94]	3	hSpCas9	negative selection	10679120
26477064	26477087	22	+	28162770	SKM1	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.43867305847049964	[22]	[29]	-4	hSpCas9	negative selection	10679121
26470785	26470808	22	+	28162770	SKM1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.948283969344227	[106]	[364]	8	hSpCas9	negative selection	10679122
26465468	26465491	22	-	28162770	SKM1	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.10644504095296031	[61]	[117]	1	hSpCas9	negative selection	10679123
26464767	26464790	22	-	28162770	SKM1	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.5378942470643774	[59]	[153]	5	hSpCas9	negative selection	10679124
26464590	26464613	22	-	28162770	SKM1	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.33915309379257486	[54]	[122]	3	hSpCas9	negative selection	10679125
26464574	26464597	22	+	28162770	SKM1	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.2691461900361897	[68]	[146]	2	hSpCas9	negative selection	10679126
26464460	26464483	22	+	28162770	SKM1	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.6457772633288117	[46]	[129]	6	hSpCas9	negative selection	10679127
26457927	26457950	22	+	28162770	PL21	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	1.2507656875592883	[55]	[57]	8	hSpCas9	negative selection	10848484
26464330	26464353	22	+	28162770	PL21	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.8015902379990454	[86]	[65]	7	hSpCas9	negative selection	10848485
26479290	26479313	22	-	28162770	PL21	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-0.7118042088454837	[142]	[37]	-5	hSpCas9	negative selection	10848486
26477064	26477087	22	+	28162770	PL21	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	1.4065904919567465	[77]	[89]	9	hSpCas9	negative selection	10848487
26470785	26470808	22	+	28162770	PL21	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.7998603855106798	[459]	[114]	-5	hSpCas9	negative selection	10848488
26465468	26465491	22	-	28162770	PL21	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	-0.33329258559175395	[274]	[94]	-2	hSpCas9	negative selection	10848489
26464767	26464790	22	-	28162770	PL21	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.37006461593163237	[207]	[116]	3	hSpCas9	negative selection	10848490
26464590	26464613	22	-	28162770	PL21	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	1.4615261674416318	[145]	[174]	9	hSpCas9	negative selection	10848491
26464574	26464597	22	+	28162770	PL21	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.22670933489322265	[268]	[136]	2	hSpCas9	negative selection	10848492
26464460	26464483	22	+	28162770	PL21	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	-0.07801607836913671	[210]	[86]	0	hSpCas9	negative selection	10848493
26457927	26457950	22	+	28162770	P31FUJ	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.5795707924098501	[40]	[71]	6	hSpCas9	negative selection	11017850
26464330	26464353	22	+	28162770	P31FUJ	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.03849981740301578	[86]	[104]	0	hSpCas9	negative selection	11017851
26479290	26479313	22	-	28162770	P31FUJ	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.31263193212014	[147]	[215]	3	hSpCas9	negative selection	11017852
26477064	26477087	22	+	28162770	P31FUJ	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	1.1534763018830416	[56]	[148]	9	hSpCas9	negative selection	11017853
26470785	26470808	22	+	28162770	P31FUJ	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.8684811314228028	[329]	[707]	8	hSpCas9	negative selection	11017854
26465468	26465491	22	-	28162770	P31FUJ	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.6175617166844877	[202]	[365]	7	hSpCas9	negative selection	11017855
26464767	26464790	22	-	28162770	P31FUJ	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.44782540560201556	[281]	[451]	5	hSpCas9	negative selection	11017856
26464590	26464613	22	-	28162770	P31FUJ	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.0927542443066821	[205]	[226]	-1	hSpCas9	negative selection	11017857
26464574	26464597	22	+	28162770	P31FUJ	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.2552987570541887	[384]	[539]	2	hSpCas9	negative selection	11017858
26464460	26464483	22	+	28162770	P31FUJ	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.29625155515612145	[227]	[328]	3	hSpCas9	negative selection	11017859
26457927	26457950	22	+	28162770	OCIAML5	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.28543695288593796	[19]	[43]	2	hSpCas9	negative selection	11187216
26464330	26464353	22	+	28162770	OCIAML5	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.5335871216337524	[30]	[80]	4	hSpCas9	negative selection	11187217
26479290	26479313	22	-	28162770	OCIAML5	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.7567426718115271	[99]	[304]	6	hSpCas9	negative selection	11187218
26477064	26477087	22	+	28162770	OCIAML5	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.9202380735055764	[64]	[61]	-5	hSpCas9	negative selection	11187219
26470785	26470808	22	+	28162770	OCIAML5	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.5998076965952184	[260]	[713]	5	hSpCas9	negative selection	11187220
26465468	26465491	22	-	28162770	OCIAML5	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.8433199195508098	[87]	[284]	7	hSpCas9	negative selection	11187221
26464767	26464790	22	-	28162770	OCIAML5	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.037281443330904496	[165]	[291]	0	hSpCas9	negative selection	11187222
26464590	26464613	22	-	28162770	OCIAML5	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.6764950062805424	[84]	[95]	-4	hSpCas9	negative selection	11187223
26464574	26464597	22	+	28162770	OCIAML5	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.02785697714425206	[143]	[264]	0	hSpCas9	negative selection	11187224
26464460	26464483	22	+	28162770	OCIAML5	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.31055362995508207	[87]	[196]	2	hSpCas9	negative selection	11187225
26457927	26457950	22	+	28162770	EOL1	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.2241080534294424	[103]	[63]	2	hSpCas9	negative selection	11356582
26464330	26464353	22	+	28162770	EOL1	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-2.2159334519792955	[96]	[10]	-8	hSpCas9	negative selection	11356583
26479290	26479313	22	-	28162770	EOL1	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.6118382067125508	[194]	[156]	5	hSpCas9	negative selection	11356584
26477064	26477087	22	+	28162770	EOL1	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.9949370994619327	[119]	[125]	8	hSpCas9	negative selection	11356585
26470785	26470808	22	+	28162770	EOL1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	-0.3545022593688314	[778]	[320]	-3	hSpCas9	negative selection	11356586
26465468	26465491	22	-	28162770	EOL1	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.33351075643969397	[475]	[315]	3	hSpCas9	negative selection	11356587
26464767	26464790	22	-	28162770	EOL1	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.3233797418730509	[341]	[143]	-2	hSpCas9	negative selection	11356588
26464590	26464613	22	-	28162770	EOL1	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.5825438999185127	[198]	[156]	5	hSpCas9	negative selection	11356589
26464574	26464597	22	+	28162770	EOL1	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	-0.23983904633034783	[389]	[173]	-2	hSpCas9	negative selection	11356590
26464460	26464483	22	+	28162770	EOL1	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	-0.3196890388091335	[243]	[102]	-2	hSpCas9	negative selection	11356591
26457927	26457950	22	+	28162770	MOLM13	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.957274222283504	[51]	[72]	7	hSpCas9	negative selection	11525948
26464330	26464353	22	+	28162770	MOLM13	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-0.48904189656353525	[98]	[50]	-3	hSpCas9	negative selection	11525949
26479290	26479313	22	-	28162770	MOLM13	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-0.011918373124502779	[204]	[146]	0	hSpCas9	negative selection	11525950
26477064	26477087	22	+	28162770	MOLM13	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.6528627779160312	[136]	[62]	-4	hSpCas9	negative selection	11525951
26470785	26470808	22	+	28162770	MOLM13	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.8011837313818861	[530]	[668]	6	hSpCas9	negative selection	11525952
26465468	26465491	22	-	28162770	MOLM13	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.6695232427142297	[359]	[413]	5	hSpCas9	negative selection	11525953
26464767	26464790	22	-	28162770	MOLM13	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.32984753795142824	[298]	[171]	-2	hSpCas9	negative selection	11525954
26464590	26464613	22	-	28162770	MOLM13	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.10680478372275026	[279]	[187]	0	hSpCas9	negative selection	11525955
26464574	26464597	22	+	28162770	MOLM13	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.8920675346798914	[353]	[474]	6	hSpCas9	negative selection	11525956
26464460	26464483	22	+	28162770	MOLM13	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.009103986900567441	[278]	[202]	0	hSpCas9	negative selection	11525957
26457927	26457950	22	+	28162770	HEL	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.17561282157305902	[93]	[67]	1	hSpCas9	negative selection	11695314
26464330	26464353	22	+	28162770	HEL	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-0.012612996612197502	[62]	[39]	0	hSpCas9	negative selection	11695315
26479290	26479313	22	-	28162770	HEL	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-0.06390222530905162	[203]	[124]	0	hSpCas9	negative selection	11695316
26477064	26477087	22	+	28162770	HEL	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	1.4437054260954136	[96]	[168]	9	hSpCas9	negative selection	11695317
26470785	26470808	22	+	28162770	HEL	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.4859664944074349	[504]	[452]	4	hSpCas9	negative selection	11695318
26465468	26465491	22	-	28162770	HEL	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.07281573074334174	[333]	[224]	0	hSpCas9	negative selection	11695319
26464767	26464790	22	-	28162770	HEL	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.6716424538336573	[285]	[114]	-4	hSpCas9	negative selection	11695320
26464590	26464613	22	-	28162770	HEL	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.6509923710563533	[227]	[92]	-4	hSpCas9	negative selection	11695321
26464574	26464597	22	+	28162770	HEL	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.36402280393429337	[221]	[182]	3	hSpCas9	negative selection	11695322
26464460	26464483	22	+	28162770	HEL	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.4606785046991272	[193]	[170]	4	hSpCas9	negative selection	11695323
26457927	26457950	22	+	28162770	MV411	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	0.06846740973745602	[59]	[52]	0	hSpCas9	negative selection	11864680
26464330	26464353	22	+	28162770	MV411	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.4664473327245713	[60]	[70]	4	hSpCas9	negative selection	11864681
26479290	26479313	22	-	28162770	MV411	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	-0.7714214764685408	[153]	[75]	-5	hSpCas9	negative selection	11864682
26477064	26477087	22	+	28162770	MV411	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	1.3942789391120467	[41]	[92]	9	hSpCas9	negative selection	11864683
26470785	26470808	22	+	28162770	MV411	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.7428293104089134	[370]	[522]	6	hSpCas9	negative selection	11864684
26465468	26465491	22	-	28162770	MV411	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	-0.19896411940540373	[247]	[181]	-1	hSpCas9	negative selection	11864685
26464767	26464790	22	-	28162770	MV411	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.5118531870149298	[173]	[208]	4	hSpCas9	negative selection	11864686
26464590	26464613	22	-	28162770	MV411	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.10619940383192528	[160]	[125]	-1	hSpCas9	negative selection	11864687
26464574	26464597	22	+	28162770	MV411	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	-0.33010747837589793	[290]	[194]	-2	hSpCas9	negative selection	11864688
26464460	26464483	22	+	28162770	MV411	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	1.4964650986226902	[137]	[327]	9	hSpCas9	negative selection	11864689
26457927	26457950	22	+	28162770	MONOMAC1	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	1.0307690704632586	[37]	[88]	8	hSpCas9	negative selection	12034046
26464330	26464353	22	+	28162770	MONOMAC1	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	0.7397693264532526	[34]	[66]	7	hSpCas9	negative selection	12034047
26479290	26479313	22	-	28162770	MONOMAC1	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.47231784095197504	[82]	[131]	5	hSpCas9	negative selection	12034048
26477064	26477087	22	+	28162770	MONOMAC1	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-0.6824636742297956	[48]	[34]	-5	hSpCas9	negative selection	12034049
26470785	26470808	22	+	28162770	MONOMAC1	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.1258824502308591	[290]	[363]	1	hSpCas9	negative selection	12034050
26465468	26465491	22	-	28162770	MONOMAC1	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	-0.4250648030654343	[170]	[145]	-4	hSpCas9	negative selection	12034051
26464767	26464790	22	-	28162770	MONOMAC1	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.19375310597261267	[134]	[176]	2	hSpCas9	negative selection	12034052
26464590	26464613	22	-	28162770	MONOMAC1	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.8554305728345818	[80]	[167]	7	hSpCas9	negative selection	12034053
26464574	26464597	22	+	28162770	MONOMAC1	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	0.006291312649972403	[184]	[212]	0	hSpCas9	negative selection	12034054
26464460	26464483	22	+	28162770	MONOMAC1	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	-0.6665221303607739	[107]	[77]	-5	hSpCas9	negative selection	12034055
26457927	26457950	22	+	28162770	OCIAML2	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	1.3748602257022138	[7]	[114]	9	hSpCas9	negative selection	12203412
26464330	26464353	22	+	28162770	OCIAML2	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-0.8185531286624683	[6]	[21]	-5	hSpCas9	negative selection	12203413
26479290	26479313	22	-	28162770	OCIAML2	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.5383589579850936	[19]	[160]	5	hSpCas9	negative selection	12203414
26477064	26477087	22	+	28162770	OCIAML2	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	0.6992951762001511	[10]	[98]	6	hSpCas9	negative selection	12203415
26470785	26470808	22	+	28162770	OCIAML2	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.5581018933011548	[86]	[709]	5	hSpCas9	negative selection	12203416
26465468	26465491	22	-	28162770	OCIAML2	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	0.19961786342396426	[51]	[330]	2	hSpCas9	negative selection	12203417
26464767	26464790	22	-	28162770	OCIAML2	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	-0.42623570588370774	[39]	[164]	-3	hSpCas9	negative selection	12203418
26464590	26464613	22	-	28162770	OCIAML2	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	0.25976311500055876	[32]	[218]	2	hSpCas9	negative selection	12203419
26464574	26464597	22	+	28162770	OCIAML2	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	-0.35063004913153095	[48]	[212]	-3	hSpCas9	negative selection	12203420
26464460	26464483	22	+	28162770	OCIAML2	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	0.534108093764502	[37]	[304]	5	hSpCas9	negative selection	12203421
26457927	26457950	22	+	28162770	OCIAML3	viability	GAAGCGGCGATCCTGCGGGGTGG	HPS4	ENSG00000100099	-0.21549601707043342	[19]	[51]	-2	hSpCas9	negative selection	12372778
26464330	26464353	22	+	28162770	OCIAML3	viability	GCATCTCAGGAGCAGAGGGAGGG	HPS4	ENSG00000100099	-0.042597699314033455	[28]	[84]	0	hSpCas9	negative selection	12372779
26479290	26479313	22	-	28162770	OCIAML3	viability	GAAGGCGATCCAACAAGAGCTGG	HPS4	ENSG00000100099	0.5802432865209394	[36]	[166]	5	hSpCas9	negative selection	12372780
26477064	26477087	22	+	28162770	OCIAML3	viability	CAGAAATGTCAGAAACACAGCGG	HPS4	ENSG00000100099	-1.931042627601734	[23]	[18]	-8	hSpCas9	negative selection	12372781
26470785	26470808	22	+	28162770	OCIAML3	viability	GCTGCCTTCAGCAACAACAGGGG	HPS4	ENSG00000100099	0.544108622887473	[106]	[470]	5	hSpCas9	negative selection	12372782
26465468	26465491	22	-	28162770	OCIAML3	viability	TAGTCTCCACGAGTTCCCGGTGG	HPS4	ENSG00000100099	-0.07660842341564157	[50]	[145]	0	hSpCas9	negative selection	12372783
26464767	26464790	22	-	28162770	OCIAML3	viability	GCCCAGCACCATCCAAAGGGTGG	HPS4	ENSG00000100099	0.7323527008784599	[64]	[325]	6	hSpCas9	negative selection	12372784
26464590	26464613	22	-	28162770	OCIAML3	viability	GGACTGCACAACTCTGCCAGGGG	HPS4	ENSG00000100099	-0.5697600940774858	[58]	[119]	-4	hSpCas9	negative selection	12372785
26464574	26464597	22	+	28162770	OCIAML3	viability	GAGGCCAAGAACCTCACCCCTGG	HPS4	ENSG00000100099	-0.4969089522190818	[78]	[168]	-4	hSpCas9	negative selection	12372786
26464460	26464483	22	+	28162770	OCIAML3	viability	TAGGAAGGCAAAATGACCTGAGG	HPS4	ENSG00000100099	-0.09650798085334639	[67]	[191]	0	hSpCas9	negative selection	12372787