Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11234
• Symbol: HPS5
• Description: HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HPS5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18306138	18306161	11	+	26472758	Jiyoye	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.22445626784750838	[268]	[236]	1	hSpCas9	negative selection	73953
18291606	18291629	11	-	26472758	Jiyoye	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.7019186470670054	[74]	[91]	5	hSpCas9	negative selection	73954
18291677	18291700	11	+	26472758	Jiyoye	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.6006441229534258	[184]	[91]	-4	hSpCas9	negative selection	73955
18283849	18283872	11	-	26472758	Jiyoye	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-2.851558886894295	[66]	[6]	-9	hSpCas9	negative selection	73956
18281949	18281972	11	-	26472758	Jiyoye	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.21453030356347752	[103]	[90]	1	hSpCas9	negative selection	73957
18306237	18306260	11	+	26472758	Jiyoye	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.0820800075398278	[227]	[181]	0	hSpCas9	negative selection	73958
18298853	18298876	11	-	26472758	Jiyoye	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	1.4677169234409242	[34]	[72]	8	hSpCas9	negative selection	73959
18296797	18296820	11	-	26472758	Jiyoye	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	2.466069070559442	[17]	[74]	9	hSpCas9	negative selection	73960
18295083	18295106	11	-	26472758	Jiyoye	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.706735663364781	[12]	[15]	5	hSpCas9	negative selection	73961
18291723	18291746	11	+	26472758	Jiyoye	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	-0.32547721978925037	[333]	[200]	-2	hSpCas9	negative selection	73962
18306138	18306161	11	+	26472758	KBM7	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.39067811132041397	[1259,1106]	[447,401]	-4	hSpCas9	negative selection	265071
18291606	18291629	11	-	26472758	KBM7	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.8964937064975715	[385,287]	[253,325]	8	hSpCas9	negative selection	265072
18291677	18291700	11	+	26472758	KBM7	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.2621514315480526	[547,483]	[267,142]	-3	hSpCas9	negative selection	265073
18283849	18283872	11	-	26472758	KBM7	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-1.7377774736379372	[494,372]	[86,36]	-8	hSpCas9	negative selection	265074
18281949	18281972	11	-	26472758	KBM7	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.34695249339264256	[393,333]	[180,248]	3	hSpCas9	negative selection	265075
18306237	18306260	11	+	26472758	KBM7	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.41548321991620163	[863,583]	[432,459]	4	hSpCas9	negative selection	265076
18298853	18298876	11	-	26472758	KBM7	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.2850053525423964	[273,288]	[190,136]	3	hSpCas9	negative selection	265077
18296797	18296820	11	-	26472758	KBM7	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.10915190898190845	[488,465]	[190,288]	1	hSpCas9	negative selection	265078
18295083	18295106	11	-	26472758	KBM7	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.9999283513358861	[115,99]	[95,105]	9	hSpCas9	negative selection	265079
18291723	18291746	11	+	26472758	KBM7	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.2779686770600365	[1131,837]	[532,575]	3	hSpCas9	negative selection	265080
18306138	18306161	11	+	26472758	Raji	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.38335699691489156	[554]	[167]	3	hSpCas9	negative selection	456189
18291606	18291629	11	-	26472758	Raji	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	1.188520298099005	[120]	[63]	9	hSpCas9	negative selection	456190
18291677	18291700	11	+	26472758	Raji	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	1.1679250773086505	[139]	[72]	8	hSpCas9	negative selection	456191
18283849	18283872	11	-	26472758	Raji	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-2.799507060234919	[179]	[5]	-9	hSpCas9	negative selection	456192
18281949	18281972	11	-	26472758	Raji	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.5029248590266461	[148]	[48]	5	hSpCas9	negative selection	456193
18306237	18306260	11	+	26472758	Raji	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.7653478670376623	[288]	[113]	7	hSpCas9	negative selection	456194
18298853	18298876	11	-	26472758	Raji	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	-0.4251115454534212	[161]	[27]	-3	hSpCas9	negative selection	456195
18296797	18296820	11	-	26472758	Raji	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.9711791517752884	[221]	[100]	8	hSpCas9	negative selection	456196
18295083	18295106	11	-	26472758	Raji	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	1.3249749704462264	[42]	[24]	9	hSpCas9	negative selection	456197
18291723	18291746	11	+	26472758	Raji	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.8801154924961072	[493]	[210]	7	hSpCas9	negative selection	456198
18306138	18306161	11	+	26472758	K562	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.5437255904253223	[1118]	[647]	-3	hSpCas9	negative selection	647307
18291606	18291629	11	-	26472758	K562	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	1.1136321201310926	[149]	[273]	8	hSpCas9	negative selection	647308
18291677	18291700	11	+	26472758	K562	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.02005909503701543	[399]	[332]	0	hSpCas9	negative selection	647309
18283849	18283872	11	-	26472758	K562	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-7.294740083441584	[371]	[1]	-9	hSpCas9	negative selection	647310
18281949	18281972	11	-	26472758	K562	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.4474589769712214	[314]	[194]	-3	hSpCas9	negative selection	647311
18306237	18306260	11	+	26472758	K562	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.31358912749446155	[732]	[768]	2	hSpCas9	negative selection	647312
18298853	18298876	11	-	26472758	K562	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.32688088785841996	[203]	[215]	2	hSpCas9	negative selection	647313
18296797	18296820	11	-	26472758	K562	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	1.4516682185176144	[300]	[694]	9	hSpCas9	negative selection	647314
18295083	18295106	11	-	26472758	K562	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	1.9370950456878564	[42]	[138]	9	hSpCas9	negative selection	647315
18291723	18291746	11	+	26472758	K562	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	1.074944497994991	[599]	[1066]	8	hSpCas9	negative selection	647316
18296806	18296829	11	-	26627737	DLD1	viability	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.20615671563875804	[242]	[115,81,8]	-2	hSpCas9	negative selection	777840
18297666	18297689	11	-	26627737	DLD1	viability	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.09379305656326675	[138]	[14,40,77]	1	hSpCas9	negative selection	777841
18305464	18305487	11	-	26627737	DLD1	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.4073112567852841	[288]	[170,252,287]	9	hSpCas9	negative selection	777842
18306234	18306257	11	-	26627737	DLD1	viability	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.1128355121918751	[646]	[243,246,87]	-1	hSpCas9	negative selection	777843
18311995	18312018	11	-	26627737	DLD1	viability	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.3477301852642465	[818]	[317,288,362]	3	hSpCas9	negative selection	777844
18317768	18317791	11	-	26627737	DLD1	viability	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	-0.026481483434350306	[131]	[29,62,30]	0	hSpCas9	negative selection	777845
18296806	18296829	11	-	26627737	GBM cells	viability after 5 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.9755552430304554	[131]	[56,14]	-9	hSpCas9	negative selection	860155
18297666	18297689	11	-	26627737	GBM cells	viability after 5 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.1094808608253437	[69]	[36,43]	1	hSpCas9	negative selection	860156
18305464	18305487	11	-	26627737	GBM cells	viability after 5 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.7130900627993039	[210]	[179,190]	8	hSpCas9	negative selection	860157
18306234	18306257	11	-	26627737	GBM cells	viability after 5 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.3571634409858281	[221]	[199,104]	5	hSpCas9	negative selection	860158
18311995	18312018	11	-	26627737	GBM cells	viability after 5 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.32314853394170806	[429]	[272,303]	5	hSpCas9	negative selection	860159
18317768	18317791	11	-	26627737	GBM cells	viability after 5 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.6094072576907008	[43]	[32,38]	8	hSpCas9	negative selection	860160
18296806	18296829	11	-	26627737	GBM cells	viability after 13 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.627702017573969	[131]	[63,31]	-6	hSpCas9	negative selection	942470
18297666	18297689	11	-	26627737	GBM cells	viability after 13 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.8819515720219351	[69]	[53,82]	8	hSpCas9	negative selection	942471
18305464	18305487	11	-	26627737	GBM cells	viability after 13 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.3986356951734523	[210]	[124,171]	5	hSpCas9	negative selection	942472
18306234	18306257	11	-	26627737	GBM cells	viability after 13 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.16936649286596753	[221]	[151,121]	2	hSpCas9	negative selection	942473
18311995	18312018	11	-	26627737	GBM cells	viability after 13 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.7835627128386106	[429]	[528,297]	8	hSpCas9	negative selection	942474
18317768	18317791	11	-	26627737	GBM cells	viability after 13 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.21555747184683716	[43]	[19,33]	2	hSpCas9	negative selection	942475
18296806	18296829	11	-	26627737	GBM cells	viability after 21 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.1408068856637188	[131]	[31,32]	-7	hSpCas9	negative selection	1024785
18297666	18297689	11	-	26627737	GBM cells	viability after 21 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	1.6051953368908194	[69]	[110,119]	9	hSpCas9	negative selection	1024786
18305464	18305487	11	-	26627737	GBM cells	viability after 21 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.15625085097148925	[210]	[121,132]	1	hSpCas9	negative selection	1024787
18306234	18306257	11	-	26627737	GBM cells	viability after 21 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.23501528055218912	[221]	[102,101]	-2	hSpCas9	negative selection	1024788
18311995	18312018	11	-	26627737	GBM cells	viability after 21 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.312336417867736	[429]	[299,280]	3	hSpCas9	negative selection	1024789
18317768	18317791	11	-	26627737	GBM cells	viability after 21 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.4878475657953887	[43]	[32,33]	5	hSpCas9	negative selection	1024790
18296806	18296829	11	-	26627737	RPE1	viability after 9 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.7835495500064782	[792]	[34,119]	-8	hSpCas9	negative selection	1107100
18297666	18297689	11	-	26627737	RPE1	viability after 9 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	2.419738391351052	[108]	[165,203]	9	hSpCas9	negative selection	1107101
18305464	18305487	11	-	26627737	RPE1	viability after 9 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.3402406586757896	[446]	[266,466]	7	hSpCas9	negative selection	1107102
18306234	18306257	11	-	26627737	RPE1	viability after 9 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.27647204460505426	[750]	[187,201]	-2	hSpCas9	negative selection	1107103
18311995	18312018	11	-	26627737	RPE1	viability after 9 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	1.142870047187301	[1051]	[735,715]	7	hSpCas9	negative selection	1107104
18317768	18317791	11	-	26627737	RPE1	viability after 9 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	7.5591224123475875	[0]	[48,71]	9	hSpCas9	negative selection	1107105
18296806	18296829	11	-	26627737	RPE1	viability after 12 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.938052666194695	[792]	[41,69]	-8	hSpCas9	negative selection	1189415
18297666	18297689	11	-	26627737	RPE1	viability after 12 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	2.2001554144513906	[108]	[119,149]	9	hSpCas9	negative selection	1189416
18305464	18305487	11	-	26627737	RPE1	viability after 12 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.701634055220993	[446]	[309,475]	8	hSpCas9	negative selection	1189417
18306234	18306257	11	-	26627737	RPE1	viability after 12 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.4817746396588165	[750]	[109,180]	-3	hSpCas9	negative selection	1189418
18311995	18312018	11	-	26627737	RPE1	viability after 12 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	1.5074748813149932	[1051]	[856,746]	8	hSpCas9	negative selection	1189419
18317768	18317791	11	-	26627737	RPE1	viability after 12 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	7.13751580153539	[0]	[31,43]	9	hSpCas9	negative selection	1189420
18296806	18296829	11	-	26627737	RPE1	viability after 15 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-2.920932854178752	[792]	[50,8]	-9	hSpCas9	negative selection	1271730
18297666	18297689	11	-	26627737	RPE1	viability after 15 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	2.7035765770984352	[108]	[208,192]	9	hSpCas9	negative selection	1271731
18305464	18305487	11	-	26627737	RPE1	viability after 15 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.1083529960232175	[446]	[265,278]	6	hSpCas9	negative selection	1271732
18306234	18306257	11	-	26627737	RPE1	viability after 15 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.5275445363147557	[750]	[97,194]	-3	hSpCas9	negative selection	1271733
18311995	18312018	11	-	26627737	RPE1	viability after 15 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	1.5048414716322802	[1051]	[926,764]	7	hSpCas9	negative selection	1271734
18317768	18317791	11	-	26627737	RPE1	viability after 15 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	6.381329275120168	[0]	[18,27]	9	hSpCas9	negative selection	1271735
18296806	18296829	11	-	26627737	RPE1	viability after 18 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.9296433526115941	[792]	[2,112]	-8	hSpCas9	negative selection	1354045
18297666	18297689	11	-	26627737	RPE1	viability after 18 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	2.880701627739844	[108]	[118,320]	9	hSpCas9	negative selection	1354046
18305464	18305487	11	-	26627737	RPE1	viability after 18 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.6159574449503475	[446]	[347,392]	8	hSpCas9	negative selection	1354047
18306234	18306257	11	-	26627737	RPE1	viability after 18 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.32598143027242565	[750]	[64,264]	-2	hSpCas9	negative selection	1354048
18311995	18312018	11	-	26627737	RPE1	viability after 18 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	1.1749511508646298	[1051]	[582,702]	6	hSpCas9	negative selection	1354049
18317768	18317791	11	-	26627737	RPE1	viability after 18 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	6.194746668282783	[0]	[12,26]	9	hSpCas9	negative selection	1354050
18296806	18296829	11	-	26627737	HeLa	viability after 8 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.2984441070044521	[347]	[109,62,24]	-8	hSpCas9	negative selection	1436360
18297666	18297689	11	-	26627737	HeLa	viability after 8 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	1.0845958346033393	[89]	[90,92,67]	8	hSpCas9	negative selection	1436361
18305464	18305487	11	-	26627737	HeLa	viability after 8 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.6392652405020104	[232]	[166,50,250]	5	hSpCas9	negative selection	1436362
18306234	18306257	11	-	26627737	HeLa	viability after 8 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-1.6123987778857614	[657]	[114,126,46]	-9	hSpCas9	negative selection	1436363
18311995	18312018	11	-	26627737	HeLa	viability after 8 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.20954774451012037	[798]	[330,340,240]	-2	hSpCas9	negative selection	1436364
18317768	18317791	11	-	26627737	HeLa	viability after 8 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.09882423378351879	[86]	[3,15,89]	1	hSpCas9	negative selection	1436365
18296806	18296829	11	-	26627737	HeLa	viability after 12 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.9732423168136513	[347]	[128,57,35]	-7	hSpCas9	negative selection	1518675
18297666	18297689	11	-	26627737	HeLa	viability after 12 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	1.4353050943623453	[89]	[92,133,70]	8	hSpCas9	negative selection	1518676
18305464	18305487	11	-	26627737	HeLa	viability after 12 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.6887939146050243	[232]	[152,188,119]	5	hSpCas9	negative selection	1518677
18306234	18306257	11	-	26627737	HeLa	viability after 12 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.8295276642735862	[657]	[74,150,230]	-6	hSpCas9	negative selection	1518678
18311995	18312018	11	-	26627737	HeLa	viability after 12 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.09350649467745542	[798]	[240,256,433]	-1	hSpCas9	negative selection	1518679
18317768	18317791	11	-	26627737	HeLa	viability after 12 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.4513826969188224	[86]	[68,11,70]	4	hSpCas9	negative selection	1518680
18296806	18296829	11	-	26627737	HeLa	viability after 15 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.8840729242211527	[347]	[69,63,97]	-6	hSpCas9	negative selection	1600990
18297666	18297689	11	-	26627737	HeLa	viability after 15 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	1.269403171297314	[89]	[115,115,27]	8	hSpCas9	negative selection	1600991
18305464	18305487	11	-	26627737	HeLa	viability after 15 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.0010298867848761	[232]	[261,111,194]	7	hSpCas9	negative selection	1600992
18306234	18306257	11	-	26627737	HeLa	viability after 15 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-1.5635085402339821	[657]	[84,119,64]	-8	hSpCas9	negative selection	1600993
18311995	18312018	11	-	26627737	HeLa	viability after 15 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.43343137828515277	[798]	[127,379,213]	-4	hSpCas9	negative selection	1600994
18317768	18317791	11	-	26627737	HeLa	viability after 15 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.030195962481144534	[86]	[1,57,49]	0	hSpCas9	negative selection	1600995
18296806	18296829	11	-	26627737	HeLa	viability after 18 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-0.8626158548123726	[347]	[49,51,97]	-6	hSpCas9	negative selection	1683305
18297666	18297689	11	-	26627737	HeLa	viability after 18 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	1.2501882831888613	[89]	[69,102,27]	8	hSpCas9	negative selection	1683306
18305464	18305487	11	-	26627737	HeLa	viability after 18 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.9149679311306598	[232]	[158,86,194]	7	hSpCas9	negative selection	1683307
18306234	18306257	11	-	26627737	HeLa	viability after 18 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-1.5482264135751103	[657]	[55,102,64]	-8	hSpCas9	negative selection	1683308
18311995	18312018	11	-	26627737	HeLa	viability after 18 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.42668396232776384	[798]	[82,320,213]	-4	hSpCas9	negative selection	1683309
18317768	18317791	11	-	26627737	HeLa	viability after 18 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.03914381003755185	[86]	[0,48,49]	0	hSpCas9	negative selection	1683310
18296806	18296829	11	-	26627737	HCT116	viability after 6 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	1.8572359113507768	[32]	[41,5]	8	hSpCas9	negative selection	1765620
18297666	18297689	11	-	26627737	HCT116	viability after 6 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.22032995487955565	[204]	[101,1]	1	hSpCas9	negative selection	1765621
18305464	18305487	11	-	26627737	HCT116	viability after 6 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.124469420251236	[497]	[452,14]	6	hSpCas9	negative selection	1765622
18306234	18306257	11	-	26627737	HCT116	viability after 6 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-1.96380664284097	[595]	[43,12]	-8	hSpCas9	negative selection	1765623
18311995	18312018	11	-	26627737	HCT116	viability after 6 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.5476468964084067	[1290]	[250,76]	-3	hSpCas9	negative selection	1765624
18317768	18317791	11	-	26627737	HCT116	viability after 6 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	2.3743410958272424	[98]	[168,31]	9	hSpCas9	negative selection	1765625
18296806	18296829	11	-	26627737	HCT116	viability after 8 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	1.548582694094816	[50]	[85,103,56]	9	hSpCas9	negative selection	1847935
18297666	18297689	11	-	26627737	HCT116	viability after 8 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.2469456329651497	[148]	[133,65,92]	2	hSpCas9	negative selection	1847936
18305464	18305487	11	-	26627737	HCT116	viability after 8 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.5446151547678855	[234]	[192,125,246]	5	hSpCas9	negative selection	1847937
18306234	18306257	11	-	26627737	HCT116	viability after 8 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.053828710017725684	[301]	[147,194,137]	0	hSpCas9	negative selection	1847938
18311995	18312018	11	-	26627737	HCT116	viability after 8 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.586026590182992	[421]	[413,422,212]	6	hSpCas9	negative selection	1847939
18317768	18317791	11	-	26627737	HCT116	viability after 8 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.204180694208572	[118]	[98,48,78]	2	hSpCas9	negative selection	1847940
18296806	18296829	11	-	26627737	HCT116	viability after 9 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	3.5932902467609145	[32]	[226,10]	9	hSpCas9	negative selection	1930250
18297666	18297689	11	-	26627737	HCT116	viability after 9 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	-0.22377816252539096	[204]	[90,11]	-1	hSpCas9	negative selection	1930251
18305464	18305487	11	-	26627737	HCT116	viability after 9 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.8168656280636124	[497]	[46,97]	-5	hSpCas9	negative selection	1930252
18306234	18306257	11	-	26627737	HCT116	viability after 9 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.6606234206677057	[595]	[331,187]	5	hSpCas9	negative selection	1930253
18311995	18312018	11	-	26627737	HCT116	viability after 9 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	-0.6694102818739267	[1290]	[118,293]	-5	hSpCas9	negative selection	1930254
18317768	18317791	11	-	26627737	HCT116	viability after 9 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	2.9378284244986714	[98]	[15,349]	9	hSpCas9	negative selection	1930255
18296806	18296829	11	-	26627737	HCT116	viability after 12 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.965397019004484	[50]	[54,61,39]	8	hSpCas9	negative selection	2012565
18297666	18297689	11	-	26627737	HCT116	viability after 12 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.44107909631657205	[148]	[60,192,70]	4	hSpCas9	negative selection	2012566
18305464	18305487	11	-	26627737	HCT116	viability after 12 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.03975617389782099	[234]	[149,92,134]	0	hSpCas9	negative selection	2012567
18306234	18306257	11	-	26627737	HCT116	viability after 12 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.7005055786817281	[301]	[106,131,53]	-6	hSpCas9	negative selection	2012568
18311995	18312018	11	-	26627737	HCT116	viability after 12 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.6251629470103797	[421]	[518,315,174]	6	hSpCas9	negative selection	2012569
18317768	18317791	11	-	26627737	HCT116	viability after 12 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.45135692988010623	[118]	[91,45,116]	4	hSpCas9	negative selection	2012570
18296806	18296829	11	-	26627737	HCT116	viability after 15 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.5103448978445844	[50]	[60,65,0]	5	hSpCas9	negative selection	2094880
18297666	18297689	11	-	26627737	HCT116	viability after 15 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.4667509457237238	[148]	[161,71,125]	4	hSpCas9	negative selection	2094881
18305464	18305487	11	-	26627737	HCT116	viability after 15 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.2778477860486976	[234]	[283,97,123]	2	hSpCas9	negative selection	2094882
18306234	18306257	11	-	26627737	HCT116	viability after 15 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.7451626422235148	[301]	[103,62,142]	-6	hSpCas9	negative selection	2094883
18311995	18312018	11	-	26627737	HCT116	viability after 15 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.3169829030369477	[421]	[358,279,273]	3	hSpCas9	negative selection	2094884
18317768	18317791	11	-	26627737	HCT116	viability after 15 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	-0.1710249668669559	[118]	[117,3,66]	-2	hSpCas9	negative selection	2094885
18296806	18296829	11	-	26627737	HCT116	viability after 18 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	1.3209649082195978	[50]	[93,37,53]	8	hSpCas9	negative selection	2177195
18297666	18297689	11	-	26627737	HCT116	viability after 18 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.20560820799666146	[148]	[83,92,70]	1	hSpCas9	negative selection	2177196
18305464	18305487	11	-	26627737	HCT116	viability after 18 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.5191092367593642	[234]	[257,58,178]	4	hSpCas9	negative selection	2177197
18306234	18306257	11	-	26627737	HCT116	viability after 18 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.17060479387555305	[301]	[197,158,134]	1	hSpCas9	negative selection	2177198
18311995	18312018	11	-	26627737	HCT116	viability after 18 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.7345838964080642	[421]	[503,223,295]	6	hSpCas9	negative selection	2177199
18317768	18317791	11	-	26627737	HCT116	viability after 18 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.7767827614487127	[118]	[145,67,82]	6	hSpCas9	negative selection	2177200
18322132	18322155	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACGTTCCGCTCTTAGTGCGCGG	HPS5	ENSG00000110756	2.1363278188896206	[88,139]	[87,136]	7	dCas9-VP64	positive selection	2437617
18322090	18322113	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTAGATCGGATCTTGTCTCCCGG	HPS5	ENSG00000110756	3.706260616818108	[44,24]	[189,2]	9	dCas9-VP64	positive selection	2437618
18322109	18322132	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGTTCCCCGGCGCTAAGCCGG	HPS5	ENSG00000110756	5.087069685881289	[439,7]	[3185,6]	9	dCas9-VP64	positive selection	2437619
18313963	18313986	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGAAG	HPS5	ENSG00000110756	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462354
18322132	18322155	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACGTTCCGCTCTTAGTGCGCGG	HPS5	ENSG00000110756	-1.1436119152153614	[106,162]	[14,22]	-9	dCas9-VP64	positive selection	2532872
18322090	18322113	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTAGATCGGATCTTGTCTCCCGG	HPS5	ENSG00000110756	1.4406103106110157	[25,38]	[16,39]	7	dCas9-VP64	positive selection	2532873
18322109	18322132	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGTTCCCCGGCGCTAAGCCGG	HPS5	ENSG00000110756	0.4034101026746393	[38,77]	[22,25]	3	dCas9-VP64	positive selection	2532874
18313963	18313986	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGAAG	HPS5	ENSG00000110756	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557609
18296045	18296068	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	-0.5133952321975456	[3,3]	[3,0]	-6	hSpCas9	positive selection	2994102
18306238	18306261	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	-0.20146814939261196	[3,3]	[3,1]	-3	hSpCas9	positive selection	2994103
18308997	18309020	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	-0.8170074598176045	[2,3]	[2,0]	-8	hSpCas9	positive selection	2994104
18306131	18306154	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	0.377141602867735	[3,3]	[4,4]	7	hSpCas9	positive selection	2994105
18296045	18296068	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	-0.18814656007303884	[3,3]	[3,0]	-3	hSpCas9	positive selection	3061960
18306238	18306261	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	-0.1339544966306622	[3,3]	[3,1]	-2	hSpCas9	positive selection	3061961
18308997	18309020	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	0.7926003216314492	[2,2]	[3,3]	9	hSpCas9	positive selection	3061962
18306131	18306154	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	0.4884795177619934	[3,3]	[4,3]	8	hSpCas9	positive selection	3061963
18311407	18311430		+	24336571	A375	resistance to PLX after 7 days	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.2815314095853665	[4,4]	[3,3]	-8	hSpCas9	positive selection	3119726
18305464	18305487		+	24336571	A375	resistance to PLX after 7 days	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.0007451506346327734	[10,13]	[11,12]	0	hSpCas9	positive selection	3119727
18305464	18305487		-	24336571	A375	resistance to PLX after 7 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.07673741943112833	[9,6]	[7,9]	2	hSpCas9	positive selection	3119728
18310825	18310848		-	24336571	A375	resistance to PLX after 7 days	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	-0.1868204048137488	[15,16]	[14,13]	-6	hSpCas9	positive selection	3119730
18310889	18310912		-	24336571	A375	resistance to PLX after 7 days	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	-0.21465805992221232	[3,3]	[3,2]	-6	hSpCas9	positive selection	3119731
18310850	18310873		-	24336571	A375	resistance to PLX after 7 days	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.052345889182598526	[4,4]	[4,3]	-1	hSpCas9	positive selection	3119732
18311407	18311430		+	24336571	A375	resistance to PLX after 14 days	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.08398069850843148	[4,2]	[1,1]	-1	hSpCas9	positive selection	3177519
18305464	18305487		+	24336571	A375	resistance to PLX after 14 days	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.7160865592269909	[13,17]	[3,3]	-8	hSpCas9	positive selection	3177520
18305464	18305487		-	24336571	A375	resistance to PLX after 14 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.3144724644439683	[6,6]	[7,7]	8	hSpCas9	positive selection	3177521
18310825	18310848		-	24336571	A375	resistance to PLX after 14 days	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	-0.13609514716408966	[10,23]	[7,6]	-1	hSpCas9	positive selection	3177523
18310889	18310912		-	24336571	A375	resistance to PLX after 14 days	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	-0.3810584119871139	[2,8]	[1,1]	-4	hSpCas9	positive selection	3177524
18310850	18310873		-	24336571	A375	resistance to PLX after 14 days	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.4756094169637486	[2,2]	[1,1]	4	hSpCas9	positive selection	3177525
18311407	18311430		+	24336571	A375	viability after 7 days	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-1.2630601761294709	[13]	[4,4]	-9	hSpCas9	negative selection	3235312
18305464	18305487		+	24336571	A375	viability after 7 days	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.31132479960771936	[10]	[10,13]	5	hSpCas9	negative selection	3235313
18305464	18305487		-	24336571	A375	viability after 7 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.1956225012044953	[10]	[9,6]	-3	hSpCas9	negative selection	3235314
18310825	18310848		-	24336571	A375	viability after 7 days	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	0.04637807387021775	[16]	[15,16]	0	hSpCas9	negative selection	3235316
18310889	18310912		-	24336571	A375	viability after 7 days	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	-0.9253695434560919	[8]	[3,3]	-8	hSpCas9	negative selection	3235317
18310850	18310873		-	24336571	A375	viability after 7 days	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.8984725489309101	[9]	[4,4]	-8	hSpCas9	negative selection	3235318
18311407	18311430		+	24336571	A375	viability after 14 days	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-1.5237667134350614	[13]	[4,2]	-9	hSpCas9	negative selection	3293105
18305464	18305487		+	24336571	A375	viability after 14 days	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.6365672400695033	[10]	[13,17]	7	hSpCas9	negative selection	3293106
18305464	18305487		-	24336571	A375	viability after 14 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.5126721558227826	[10]	[6,6]	-6	hSpCas9	negative selection	3293107
18310825	18310848		-	24336571	A375	viability after 14 days	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	0.10480515657965678	[16]	[10,23]	1	hSpCas9	negative selection	3293109
18310889	18310912		-	24336571	A375	viability after 14 days	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	-0.38556764235017205	[8]	[2,8]	-4	hSpCas9	negative selection	3293110
18310850	18310873		-	24336571	A375	viability after 14 days	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-1.3533588947867585	[9]	[2,2]	-9	hSpCas9	negative selection	3293111
18305464	18305487	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.058578095813757426	[133,184]	[0,0]	0	hSpCas9	positive selection	3354021
18305464	18305487	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.3685431766854085	[118,117]	[0,0]	2	hSpCas9	positive selection	3354022
18311386	18311409	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	2.243781682451111	[201,152]	[0,9]	7	hSpCas9	positive selection	3354023
18311407	18311430	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.1698633701954957	[271,271]	[1,1]	0	hSpCas9	positive selection	3373239
18310740	18310763	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3373240
18310850	18310873	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-1.6099525282638267	[466,466]	[0,0]	-9	hSpCas9	positive selection	3373241
18296044	18296067	11	+	26780180	HT29	viability (Avana library 4 designs)	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	2.04207387903878	[]	[]	7	hSpCas9	negative selection	3431396
18306237	18306260	11	+	26780180	HT29	viability (Avana library 4 designs)	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.668879218913254	[]	[]	2	hSpCas9	negative selection	3431397
18308997	18309020	11	-	26780180	HT29	viability (Avana library 4 designs)	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	1.10069482294819	[]	[]	4	hSpCas9	negative selection	3431398
18306130	18306153	11	+	26780180	HT29	viability (Avana library 4 designs)	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	0.962707458783816	[]	[]	4	hSpCas9	negative selection	3431399
18306130	18306153	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	-3.40231630807598	[]	[]	-4	hSpCas9	negative selection	3517024
18306237	18306260	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	2.75167641960658	[]	[]	4	hSpCas9	negative selection	3517025
18296044	18296067	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	-1.47111088699427	[]	[]	-2	hSpCas9	negative selection	3517026
18308997	18309020	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	-10.9229782305332	[]	[]	-8	hSpCas9	negative selection	3517027
18305464	18305487	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-1.62246068456898	[]	[]	-2	hSpCas9	negative selection	3517028
18296008	18296031	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCCTGAAGAGACACAAGAGG	HPS5	ENSG00000110756	-3.40524282658592	[]	[]	-4	hSpCas9	negative selection	3517029
18306130	18306153	11	+	26780180	A375	viability (Avana lentiGuide)	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	-0.129530182068134	[]	[]	0	hSpCas9	negative selection	3625683
18306237	18306260	11	+	26780180	A375	viability (Avana lentiGuide)	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	1.49251626345081	[]	[]	1	hSpCas9	negative selection	3625684
18296044	18296067	11	+	26780180	A375	viability (Avana lentiGuide)	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	1.61885761535913	[]	[]	1	hSpCas9	negative selection	3625685
18308997	18309020	11	-	26780180	A375	viability (Avana lentiGuide)	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	-7.92701249836912	[]	[]	-9	hSpCas9	negative selection	3625686
18305464	18305487	11	+	26780180	A375	viability (Avana lentiGuide)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-3.96556761601241	[]	[]	-7	hSpCas9	negative selection	3625687
18296008	18296031	11	+	26780180	A375	viability (Avana lentiGuide)	ACAGCCTGAAGAGACACAAGAGG	HPS5	ENSG00000110756	19.1857746826815	[]	[]	8	hSpCas9	negative selection	3625688
18306130	18306153	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	-0.3195185513596609	[5]	[4,4]	-5	hSpCas9	positive selection	3734342
18306237	18306260	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.03179836476882604	[4]	[5,3]	0	hSpCas9	positive selection	3734343
18296044	18296067	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	-0.06397870359461144	[5]	[5,4]	-1	hSpCas9	positive selection	3734344
18308997	18309020	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	-0.5496417797362922	[7]	[4,4]	-7	hSpCas9	positive selection	3734345
18305464	18305487	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.10611409559527737	[5]	[6,5]	2	hSpCas9	positive selection	3734346
18296008	18296031	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCCTGAAGAGACACAAGAGG	HPS5	ENSG00000110756	-0.060277705546342625	[5]	[4,5]	-1	hSpCas9	positive selection	3734347
18306130	18306153	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTACCTGAGAGTAATCACAGGG	HPS5	ENSG00000110756	0.24225396219608714	[5]	[6,4]	6	hSpCas9	positive selection	3842949
18306237	18306260	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	-0.19100607623172514	[5]	[4,3]	-3	hSpCas9	positive selection	3842950
18296044	18296067	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGGTAATGGAATGCCGAACGG	HPS5	ENSG00000110756	0.2740085694678111	[5]	[5,5]	7	hSpCas9	positive selection	3842951
18308997	18309020	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACAGTTAGATTATTTGGATGG	HPS5	ENSG00000110756	0.45418350456573375	[3]	[2,6]	9	hSpCas9	positive selection	3842952
18305464	18305487	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.2643975664008234	[5]	[5,5]	7	hSpCas9	positive selection	3842953
18296008	18296031	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCCTGAAGAGACACAAGAGG	HPS5	ENSG00000110756	-0.8282078819805949	[6]	[1,3]	-8	hSpCas9	positive selection	3842954
18311407	18311430	11	+	26780180	A375	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.713482127183893	[]	[]	2	hSpCas9	negative selection	3949006
18311386	18311409	11	-	26780180	A375	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	2.14224989958236	[]	[]	9	hSpCas9	negative selection	3949007
18310740	18310763	11	-	26780180	A375	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.983628668434702	[]	[]	4	hSpCas9	negative selection	3949008
18305464	18305487	11	+	26780180	A375	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.50063196062021	[]	[]	1	hSpCas9	negative selection	3949009
18305464	18305487	11	-	26780180	A375	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.88798133546514	[]	[]	9	hSpCas9	negative selection	3949010
18310850	18310873	11	-	26780180	A375	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.805531768911788	[]	[]	3	hSpCas9	negative selection	3949011
18311407	18311430	11	+	26780180	HT29	viability (GeCKOv2 library)	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.6948726061984	[]	[]	2	hSpCas9	negative selection	4056972
18311386	18311409	11	-	26780180	HT29	viability (GeCKOv2 library)	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	1.88516632799527	[]	[]	9	hSpCas9	negative selection	4056973
18310740	18310763	11	-	26780180	HT29	viability (GeCKOv2 library)	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.743241858020666	[]	[]	3	hSpCas9	negative selection	4056974
18305464	18305487	11	+	26780180	HT29	viability (GeCKOv2 library)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	1.01901809162854	[]	[]	4	hSpCas9	negative selection	4056975
18305464	18305487	11	-	26780180	HT29	viability (GeCKOv2 library)	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	1.38607654610616	[]	[]	7	hSpCas9	negative selection	4056976
18310850	18310873	11	-	26780180	HT29	viability (GeCKOv2 library)	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.661088519159197	[]	[]	2	hSpCas9	negative selection	4056977
18311407	18311430	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.20558428271463824	[1]	[2,0]	5	hSpCas9	positive selection	4143280
18305464	18305487	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.13378905130630847	[3]	[2,1]	-3	hSpCas9	positive selection	4143281
18305464	18305487	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.23287308217832492	[2]	[1,2]	6	hSpCas9	positive selection	4143282
18310825	18310848	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	0.09805980900456242	[3]	[2,2]	2	hSpCas9	positive selection	4143284
18310889	18310912	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	-0.4599767235476252	[2]	[1,0]	-8	hSpCas9	positive selection	4143285
18310850	18310873	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.7256102872116625	[2]	[0,0]	-9	hSpCas9	positive selection	4143286
18311407	18311430	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.47532337900366667	[3]	[3,2,1,0]	3	hSpCas9	positive selection	4207302
18305464	18305487	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.0490985923603033	[3]	[1,1,1,0]	0	hSpCas9	positive selection	4207303
18305464	18305487	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.6654519112241183	[2]	[0,0,0,3]	4	hSpCas9	positive selection	4207304
18310825	18310848	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGAGTCACAGCTCTCTGCTGG	HPS5	ENSG00000110756	0.7663467431389648	[4]	[0,3,1,4]	5	hSpCas9	positive selection	4207306
18310889	18310912	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATTAAATCAAGAGCGTCGTGG	HPS5	ENSG00000110756	0.6155362214815022	[3]	[0,0,0,3]	4	hSpCas9	positive selection	4207307
18310850	18310873	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	1.118941357794875	[2]	[3,5,3,0]	8	hSpCas9	positive selection	4207308
18305464	18305487	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.2411293377141525	[3]	[3,2]	5	hSpCas9	positive selection	4275734
18305464	18305487	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.2568930439759666	[3]	[2,0]	-5	hSpCas9	positive selection	4275735
18311386	18311409	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.1765860337224871	[3]	[3,1]	-4	hSpCas9	positive selection	4275736
18311407	18311430	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.09702338127681481	[3]	[3,1]	-2	hSpCas9	positive selection	4339994
18310740	18310763	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.39718398061203103	[2]	[1,0]	-7	hSpCas9	positive selection	4339995
18310850	18310873	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.015664793733900062	[4]	[4,2]	0	hSpCas9	positive selection	4339996
18296046	18296068	11	+	27760321	OCIAML3	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	-0.19811077687443113	[278,257]	[110,276]	-2	hSpCas9	negative selection	4407935
18296797	18296819	11	-	27760321	OCIAML3	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.8063795471655406	[468,445]	[418,896]	8	hSpCas9	negative selection	4407936
18306130	18306152	11	+	27760321	OCIAML3	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	-0.1184325991723254	[157,115]	[125,60]	-1	hSpCas9	negative selection	4407937
18306234	18306256	11	-	27760321	OCIAML3	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.39180356631202595	[672,585]	[369,379]	-4	hSpCas9	negative selection	4407938
18309006	18309028	11	+	27760321	OCIAML3	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	0.29975789276891796	[69,57]	[56,66]	3	hSpCas9	negative selection	4407939
18296046	18296068	11	+	27760321	OCIAML2	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.07959392724501835	[278,257]	[191,278]	1	hSpCas9	negative selection	4491398
18296797	18296819	11	-	27760321	OCIAML2	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.5275438123760997	[468,445]	[471,615]	7	hSpCas9	negative selection	4491399
18306130	18306152	11	+	27760321	OCIAML2	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.891934635957217	[157,115]	[198,209]	9	hSpCas9	negative selection	4491400
18306234	18306256	11	-	27760321	OCIAML2	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.35330735291169635	[672,585]	[503,839]	5	hSpCas9	negative selection	4491401
18309006	18309028	11	+	27760321	OCIAML2	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-1.34091271946712	[69,57]	[31,4]	-8	hSpCas9	negative selection	4491402
18296046	18296068	11	+	27760321	MV411	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.07055690989067243	[278,257]	[38,406]	0	hSpCas9	negative selection	4574861
18296797	18296819	11	-	27760321	MV411	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.9318015574106633	[468,445]	[616,515]	7	hSpCas9	negative selection	4574862
18306130	18306152	11	+	27760321	MV411	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	1.0472040079840945	[157,115]	[51,384]	7	hSpCas9	negative selection	4574863
18306234	18306256	11	-	27760321	MV411	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	1.1827582131805028	[672,585]	[1140,639]	8	hSpCas9	negative selection	4574864
18309006	18309028	11	+	27760321	MV411	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	0.3285051863886501	[69,57]	[51,53]	2	hSpCas9	negative selection	4574865
18296046	18296068	11	+	27760321	HL60	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.4600084265573276	[278,257]	[275,328]	5	hSpCas9	negative selection	4658324
18296797	18296819	11	-	27760321	HL60	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.41675537944386964	[468,445]	[399,604]	5	hSpCas9	negative selection	4658325
18306130	18306152	11	+	27760321	HL60	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	-0.3694320665590092	[157,115]	[79,91]	-4	hSpCas9	negative selection	4658326
18306234	18306256	11	-	27760321	HL60	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.37203075986578116	[672,585]	[342,452]	-4	hSpCas9	negative selection	4658327
18309006	18309028	11	+	27760321	HL60	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-1.6434021768025922	[69,57]	[21,10]	-9	hSpCas9	negative selection	4658328
18296046	18296068	11	+	27760321	HT1080	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	-1.5914281120267946	[257,201]	[17,43]	-5	hSpCas9	negative selection	4741787
18296797	18296819	11	-	27760321	HT1080	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.5944905070553701	[445,347]	[223,254]	3	hSpCas9	negative selection	4741788
18306130	18306152	11	+	27760321	HT1080	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.4365509509758938	[115,90]	[51,59]	2	hSpCas9	negative selection	4741789
18306234	18306256	11	-	27760321	HT1080	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.19549068059836427	[585,456]	[147,217]	-1	hSpCas9	negative selection	4741790
18309006	18309028	11	+	27760321	HT1080	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-4.358155539743308	[57,44]	[0,0]	-8	hSpCas9	negative selection	4741791
18296046	18296068	11	+	27760321	HT29	viability after 7 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.21848445696052343	[257,201]	[342,479,212]	3	hSpCas9	negative selection	4825250
18296797	18296819	11	-	27760321	HT29	viability after 7 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.2345361181752832	[445,347]	[905,424,515]	3	hSpCas9	negative selection	4825251
18306130	18306152	11	+	27760321	HT29	viability after 7 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.19204560757090605	[115,90]	[242,170,57]	3	hSpCas9	negative selection	4825252
18306234	18306256	11	-	27760321	HT29	viability after 7 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.5179803963574837	[585,456]	[593,425,403]	-6	hSpCas9	negative selection	4825253
18309006	18309028	11	+	27760321	HT29	viability after 7 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-0.4634757616963867	[57,44]	[115,32,5]	-6	hSpCas9	negative selection	4825254
18296046	18296068	11	+	27760321	HT29	viability after 25 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.325071006285287	[257,201]	[175,346,490]	3	hSpCas9	negative selection	4908713
18296797	18296819	11	-	27760321	HT29	viability after 25 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.6690988469613408	[445,347]	[901,577,665]	7	hSpCas9	negative selection	4908714
18306130	18306152	11	+	27760321	HT29	viability after 25 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.7240748065144929	[115,90]	[108,273,209]	8	hSpCas9	negative selection	4908715
18306234	18306256	11	-	27760321	HT29	viability after 25 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.11184308362547435	[585,456]	[445,630,586]	-1	hSpCas9	negative selection	4908716
18309006	18309028	11	+	27760321	HT29	viability after 25 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	0.42291867524851146	[57,44]	[33,68,142]	4	hSpCas9	negative selection	4908717
18296046	18296068	11	+	27760321	HT29	viability after 22 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.25923885564643007	[257,201]	[356,259,336]	2	hSpCas9	negative selection	4992176
18296797	18296819	11	-	27760321	HT29	viability after 22 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.8279879611997476	[445,347]	[1056,626,752]	8	hSpCas9	negative selection	4992177
18306130	18306152	11	+	27760321	HT29	viability after 22 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.5792369516975093	[115,90]	[129,205,201]	6	hSpCas9	negative selection	4992178
18306234	18306256	11	-	27760321	HT29	viability after 22 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.23104931421115033	[585,456]	[566,505,465]	-2	hSpCas9	negative selection	4992179
18309006	18309028	11	+	27760321	HT29	viability after 22 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	0.33642521102070466	[57,44]	[52,100,71]	3	hSpCas9	negative selection	4992180
18296046	18296068	11	+	27760321	HT29	viability after 19 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.3374409846671304	[257,201]	[219,317,442]	3	hSpCas9	negative selection	5075639
18296797	18296819	11	-	27760321	HT29	viability after 19 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.6960373609059558	[445,347]	[924,645,657]	7	hSpCas9	negative selection	5075640
18306130	18306152	11	+	27760321	HT29	viability after 19 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.5829825048676787	[115,90]	[345,169,38]	6	hSpCas9	negative selection	5075641
18306234	18306256	11	-	27760321	HT29	viability after 19 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.3926927851185804	[585,456]	[486,532,349]	-4	hSpCas9	negative selection	5075642
18309006	18309028	11	+	27760321	HT29	viability after 19 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-0.9882171789427971	[57,44]	[62,12,16]	-6	hSpCas9	negative selection	5075643
18296046	18296068	11	+	27760321	HT29	viability after 16 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.5872072970130942	[257,201]	[283,318,548]	6	hSpCas9	negative selection	5159102
18296797	18296819	11	-	27760321	HT29	viability after 16 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.6510619370127477	[445,347]	[575,690,813]	7	hSpCas9	negative selection	5159103
18306130	18306152	11	+	27760321	HT29	viability after 16 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.278332094519365	[115,90]	[249,54,128]	3	hSpCas9	negative selection	5159104
18306234	18306256	11	-	27760321	HT29	viability after 16 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.139815689318663	[585,456]	[328,781,451]	-1	hSpCas9	negative selection	5159105
18309006	18309028	11	+	27760321	HT29	viability after 16 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-2.8013180100629023	[57,44]	[10,9,3]	-9	hSpCas9	negative selection	5159106
18296046	18296068	11	+	27760321	HT29	viability after 13 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	0.39548303501988546	[257,201]	[372,464,222]	5	hSpCas9	negative selection	5242565
18296797	18296819	11	-	27760321	HT29	viability after 13 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.6961033801601522	[445,347]	[900,812,536]	8	hSpCas9	negative selection	5242566
18306130	18306152	11	+	27760321	HT29	viability after 13 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.31673972804990114	[115,90]	[169,150,128]	4	hSpCas9	negative selection	5242567
18306234	18306256	11	-	27760321	HT29	viability after 13 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.30180935465740466	[585,456]	[574,422,474]	-4	hSpCas9	negative selection	5242568
18309006	18309028	11	+	27760321	HT29	viability after 13 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-1.262006246645964	[57,44]	[53,18,2]	-8	hSpCas9	negative selection	5242569
18296046	18296068	11	+	27760321	HT29	viability after 10 days	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	-0.052000763998620636	[257,201]	[286,189,349]	0	hSpCas9	negative selection	5326028
18296797	18296819	11	-	27760321	HT29	viability after 10 days	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.5857255452992804	[445,347]	[686,757,785]	7	hSpCas9	negative selection	5326029
18306130	18306152	11	+	27760321	HT29	viability after 10 days	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.19499696884309303	[115,90]	[223,115,103]	2	hSpCas9	negative selection	5326030
18306234	18306256	11	-	27760321	HT29	viability after 10 days	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.24478236007826298	[585,456]	[536,607,505]	-3	hSpCas9	negative selection	5326031
18309006	18309028	11	+	27760321	HT29	viability after 10 days	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	-1.5794856591111652	[57,44]	[41,21,0]	-8	hSpCas9	negative selection	5326032
18296046	18296068	11	+	27760321	MOLM13	viability	TGGTAATGGAATGCCGAACGGG	HPS5	ENSG00000110756	1.821014268423167	[278,257]	[248,778]	9	hSpCas9	negative selection	5409491
18296797	18296819	11	-	27760321	MOLM13	viability	GTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	1.1980501702247297	[468,445]	[445,717]	8	hSpCas9	negative selection	5409492
18306130	18306152	11	+	27760321	MOLM13	viability	GTTACCTGAGAGTAATCACAGG	HPS5	ENSG00000110756	0.07069385954008478	[157,115]	[141,27]	0	hSpCas9	negative selection	5409493
18306234	18306256	11	-	27760321	MOLM13	viability	TGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.5802604507035494	[672,585]	[465,583]	4	hSpCas9	negative selection	5409494
18309006	18309028	11	+	27760321	MOLM13	viability	TAATCTAACTGTACAACACAGG	HPS5	ENSG00000110756	3.222360767456144	[69,57]	[610,100]	9	hSpCas9	negative selection	5409495
18322090	18322113	11	+	27661255	K562	viability	GTAGATCGGATCTTGTCTCCCGG	HPS5	ENSG00000110756	-0.508849722959762	[1741,1822]	[1170,853]	-7	dCas9-KRAB	negative selection	5485476
18322059	18322082	11	-	27661255	K562	viability	GCGAGGTACTGCCCTGGATGTGG	HPS5	ENSG00000110756	-0.07916139945071513	[674,891]	[582,594]	-3	dCas9-KRAB	negative selection	5485477
18305464	18305487	11	+	27260156	BXPC3	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.034421820903434514	[473]	[441,433,478,598]	0	hSpCas9	negative selection	5548194
18305464	18305487	11	-	27260156	BXPC3	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.0014754789485691144	[496]	[416,479,647,551]	0	hSpCas9	negative selection	5548195
18311386	18311409	11	-	27260156	BXPC3	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.001841960922317476	[807]	[798,842,803,938]	0	hSpCas9	negative selection	5548196
18311407	18311430	11	+	27260156	BXPC3	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.08971027501891515	[665]	[695,648,646,610]	-2	hSpCas9	negative selection	5612454
18310740	18310763	11	-	27260156	BXPC3	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.08062432018525101	[198]	[131,213,172,282]	-2	hSpCas9	negative selection	5612455
18310850	18310873	11	-	27260156	BXPC3	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.10433438236376258	[1298]	[1191,1104,1393,1388]	-2	hSpCas9	negative selection	5612456
18305464	18305487	11	+	27260156	A673	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.04385191833152596	[473]	[528,564,481,774]	1	hSpCas9	negative selection	5669445
18305464	18305487	11	-	27260156	A673	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.05885797152698981	[496]	[637,605,599,644]	1	hSpCas9	negative selection	5669446
18311386	18311409	11	-	27260156	A673	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.305625827362299	[807]	[813,812,691,824]	-6	hSpCas9	negative selection	5669447
18311407	18311430	11	+	27260156	A673	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.018332456044321987	[665]	[899,956,603,783]	0	hSpCas9	negative selection	5733705
18310740	18310763	11	-	27260156	A673	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.4311583846141245	[198]	[261,165,130,158]	-8	hSpCas9	negative selection	5733706
18310850	18310873	11	-	27260156	A673	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.060420966917989816	[1298]	[1619,1361,1471,1546]	-1	hSpCas9	negative selection	5733707
18305464	18305487	11	+	27260156	A375	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.3098802350078474	[473]	[867,665,705,520]	4	hSpCas9	negative selection	5790696
18305464	18305487	11	-	27260156	A375	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.1161354668775615	[496]	[631,913,389,618]	1	hSpCas9	negative selection	5790697
18311386	18311409	11	-	27260156	A375	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.10520168081405412	[807]	[1283,1270,818,751]	1	hSpCas9	negative selection	5790698
18311407	18311430	11	+	27260156	A375	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.03286541978858004	[665]	[918,843,723,710]	0	hSpCas9	negative selection	5854956
18310740	18310763	11	-	27260156	A375	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.23388237204272855	[198]	[212,311,416,167]	3	hSpCas9	negative selection	5854957
18310850	18310873	11	-	27260156	A375	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.01972885439894778	[1298]	[1703,1463,1630,1212]	0	hSpCas9	negative selection	5854958
18305464	18305487	11	+	27260156	COLO741	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.15009815078603592	[473]	[763,638,622]	3	hSpCas9	negative selection	5911947
18305464	18305487	11	-	27260156	COLO741	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.11238182176978219	[496]	[694,738,628]	2	hSpCas9	negative selection	5911948
18311386	18311409	11	-	27260156	COLO741	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.16228838765845877	[807]	[1176,984,645]	-3	hSpCas9	negative selection	5911949
18311407	18311430	11	+	27260156	COLO741	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.05812008241545391	[665]	[776,881,789]	-1	hSpCas9	negative selection	5976207
18310740	18310763	11	-	27260156	COLO741	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.8986766597794136	[198]	[177,93,139]	-9	hSpCas9	negative selection	5976208
18310850	18310873	11	-	27260156	COLO741	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.03472326991553265	[1298]	[1730,1789,1586]	0	hSpCas9	negative selection	5976209
18305464	18305487	11	+	27260156	CAL120	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.3346423521546323	[473]	[798,893,549]	5	hSpCas9	negative selection	6033198
18305464	18305487	11	-	27260156	CAL120	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.17408703112808216	[496]	[863,720,535]	2	hSpCas9	negative selection	6033199
18311386	18311409	11	-	27260156	CAL120	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.27062153676871414	[807]	[1682,869,1156]	4	hSpCas9	negative selection	6033200
18311407	18311430	11	+	27260156	CAL120	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.025321601245305803	[665]	[1301,567,730]	0	hSpCas9	negative selection	6097458
18310740	18310763	11	-	27260156	CAL120	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.2985289376902267	[198]	[316,194,110]	-4	hSpCas9	negative selection	6097459
18310850	18310873	11	-	27260156	CAL120	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.16086658869721981	[1298]	[1346,1348,1622]	-2	hSpCas9	negative selection	6097460
18305464	18305487	11	+	27260156	CADOES1	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.13111291325948343	[473]	[332,702,387,508]	2	hSpCas9	negative selection	6154449
18305464	18305487	11	-	27260156	CADOES1	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.0634634485611462	[496]	[455,409,467,434]	-1	hSpCas9	negative selection	6154450
18311386	18311409	11	-	27260156	CADOES1	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.23533726844267755	[807]	[684,1084,743,1030]	4	hSpCas9	negative selection	6154451
18311407	18311430	11	+	27260156	CADOES1	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.13025740867971547	[665]	[624,882,688,508]	2	hSpCas9	negative selection	6218709
18310740	18310763	11	-	27260156	CADOES1	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.08812727159525013	[198]	[190,149,164,190]	-1	hSpCas9	negative selection	6218710
18310850	18310873	11	-	27260156	CADOES1	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.10055664020375898	[1298]	[1231,1092,1026,1155]	-2	hSpCas9	negative selection	6218711
18305464	18305487	11	+	27260156	EWS502	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.4151720637686986	[473]	[718,503,633,829]	7	hSpCas9	negative selection	6275700
18305464	18305487	11	-	27260156	EWS502	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.29260605294704733	[496]	[709,627,722,498]	5	hSpCas9	negative selection	6275701
18311386	18311409	11	-	27260156	EWS502	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.26799279731790515	[807]	[713,602,715,818]	-5	hSpCas9	negative selection	6275702
18311407	18311430	11	+	27260156	EWS502	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.1642314368152632	[665]	[753,659,949,807]	3	hSpCas9	negative selection	6339960
18310740	18310763	11	-	27260156	EWS502	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.24261769203119865	[198]	[129,195,373,319]	4	hSpCas9	negative selection	6339961
18310850	18310873	11	-	27260156	EWS502	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.09399794586017385	[1298]	[1406,1419,1508,1547]	1	hSpCas9	negative selection	6339962
18305464	18305487	11	+	27260156	EW8	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.06908455829375824	[473]	[547,276,254,421]	-1	hSpCas9	negative selection	6396951
18305464	18305487	11	-	27260156	EW8	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.3585902093521117	[496]	[230,344,262,415]	-6	hSpCas9	negative selection	6396952
18311386	18311409	11	-	27260156	EW8	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.20361120386477993	[807]	[568,656,415,656]	-4	hSpCas9	negative selection	6396953
18311407	18311430	11	+	27260156	EW8	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.24248718010163273	[665]	[468,424,340,608]	-4	hSpCas9	negative selection	6461211
18310740	18310763	11	-	27260156	EW8	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.004748101117269865	[198]	[126,119,192,192]	0	hSpCas9	negative selection	6461212
18310850	18310873	11	-	27260156	EW8	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.0806000059706069	[1298]	[1283,991,717,1063]	-1	hSpCas9	negative selection	6461213
18305464	18305487	11	+	27260156	CORL105	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.04152283074086498	[473]	[509,529,554,562]	-1	hSpCas9	negative selection	6518202
18305464	18305487	11	-	27260156	CORL105	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.13601067781843457	[496]	[532,531,517,532]	-3	hSpCas9	negative selection	6518203
18311386	18311409	11	-	27260156	CORL105	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.10583372191625473	[807]	[868,901,922,827]	-2	hSpCas9	negative selection	6518204
18311407	18311430	11	+	27260156	CORL105	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.1632556219385926	[665]	[716,494,841,757]	-3	hSpCas9	negative selection	6582462
18310740	18310763	11	-	27260156	CORL105	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.3570338438223337	[198]	[137,214,229,149]	-6	hSpCas9	negative selection	6582463
18310850	18310873	11	-	27260156	CORL105	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.030041783519429988	[1298]	[1505,1587,1902,1266]	0	hSpCas9	negative selection	6582464
18305464	18305487	11	+	27260156	HS294T	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.12144000314055979	[473]	[206,232,149,205]	1	hSpCas9	negative selection	6639453
18305464	18305487	11	-	27260156	HS294T	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.153123233912759	[496]	[166,163,176,379]	2	hSpCas9	negative selection	6639454
18311386	18311409	11	-	27260156	HS294T	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.4653375741572241	[807]	[352,492,463,416]	6	hSpCas9	negative selection	6639455
18311407	18311430	11	+	27260156	HS294T	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.6558077376940002	[665]	[641,239,341,374]	8	hSpCas9	negative selection	6703713
18310740	18310763	11	-	27260156	HS294T	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.1285370078863468	[198]	[82,110,78,57]	1	hSpCas9	negative selection	6703714
18310850	18310873	11	-	27260156	HS294T	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.10331097971122194	[1298]	[347,540,504,486]	-1	hSpCas9	negative selection	6703715
18305464	18305487	11	+	27260156	HCC44	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.03914264344254649	[473]	[825,353,424,512]	0	hSpCas9	negative selection	6760704
18305464	18305487	11	-	27260156	HCC44	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.3958885157407921	[496]	[478,945,1054,481]	6	hSpCas9	negative selection	6760705
18311386	18311409	11	-	27260156	HCC44	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.10748802454789574	[807]	[963,698,1029,1273]	1	hSpCas9	negative selection	6760706
18311407	18311430	11	+	27260156	HCC44	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.32321159357682516	[665]	[432,580,901,528]	-5	hSpCas9	negative selection	6824964
18310740	18310763	11	-	27260156	HCC44	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.4075296425000208	[198]	[114,184,173,195]	-6	hSpCas9	negative selection	6824965
18310850	18310873	11	-	27260156	HCC44	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.22216334173115593	[1298]	[1591,886,1723,996]	-4	hSpCas9	negative selection	6824966
18305464	18305487	11	+	27260156	G402	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.01959940665198912	[473]	[485,558,720,561]	0	hSpCas9	negative selection	6881955
18305464	18305487	11	-	27260156	G402	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.12677653714443365	[496]	[741,523,472,507]	-1	hSpCas9	negative selection	6881956
18311386	18311409	11	-	27260156	G402	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.48710181763257693	[807]	[623,694,734,742]	-6	hSpCas9	negative selection	6881957
18311407	18311430	11	+	27260156	G402	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.39526260981631456	[665]	[1143,920,1154,1053]	5	hSpCas9	negative selection	6946215
18310740	18310763	11	-	27260156	G402	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.44665668374057044	[198]	[743,211,274,152]	5	hSpCas9	negative selection	6946216
18310850	18310873	11	-	27260156	G402	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.1802022842717872	[1298]	[2423,1257,1267,2262]	2	hSpCas9	negative selection	6946217
18305464	18305487	11	+	27260156	L33	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.09784871901954746	[473]	[346,172,304,518]	-2	hSpCas9	negative selection	7003206
18305464	18305487	11	-	27260156	L33	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.11921104778560387	[496]	[486,186,254,479]	-3	hSpCas9	negative selection	7003207
18311386	18311409	11	-	27260156	L33	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.006930859097514563	[807]	[830,339,606,591]	0	hSpCas9	negative selection	7003208
18311407	18311430	11	+	27260156	L33	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.21141714518427562	[665]	[555,241,371,562]	-5	hSpCas9	negative selection	7067466
18310740	18310763	11	-	27260156	L33	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.18177719557075478	[198]	[251,104,91,246]	4	hSpCas9	negative selection	7067467
18310850	18310873	11	-	27260156	L33	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.35888338661621133	[1298]	[992,460,612,958]	-7	hSpCas9	negative selection	7067468
18305464	18305487	11	+	27260156	K562	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.3566616839184214	[473]	[1122,387,452,260]	4	hSpCas9	negative selection	7124457
18305464	18305487	11	-	27260156	K562	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.46810812618809683	[496]	[256,577,198,255]	-5	hSpCas9	negative selection	7124458
18311386	18311409	11	-	27260156	K562	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.04482073017075272	[807]	[715,961,540,586]	0	hSpCas9	negative selection	7124459
18311407	18311430	11	+	27260156	K562	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.4175092279211604	[665]	[1246,698,744,526]	5	hSpCas9	negative selection	7188717
18310740	18310763	11	-	27260156	K562	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.009221274780877309	[198]	[146,414,101,68]	0	hSpCas9	negative selection	7188718
18310850	18310873	11	-	27260156	K562	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.6449977810690425	[1298]	[1195,784,496,531]	-6	hSpCas9	negative selection	7188719
18305464	18305487	11	+	27260156	HT29	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.41393752848392024	[473]	[615,1142,588,740]	7	hSpCas9	negative selection	7245708
18305464	18305487	11	-	27260156	HT29	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.09727577547757658	[496]	[713,647,614,612]	1	hSpCas9	negative selection	7245709
18311386	18311409	11	-	27260156	HT29	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.21495233333418107	[807]	[820,980,816,777]	-4	hSpCas9	negative selection	7245710
18311407	18311430	11	+	27260156	HT29	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.04549701630911979	[665]	[791,834,796,720]	-1	hSpCas9	negative selection	7309968
18310740	18310763	11	-	27260156	HT29	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.0620481793019132	[198]	[233,420,174,124]	-1	hSpCas9	negative selection	7309969
18310850	18310873	11	-	27260156	HT29	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.1257319933221086	[1298]	[1427,1766,1623,1036]	-3	hSpCas9	negative selection	7309970
18305464	18305487	11	+	27260156	MHHES1	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.3294134605872059	[473]	[798,615,692,588]	6	hSpCas9	negative selection	7366959
18305464	18305487	11	-	27260156	MHHES1	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.08090699232371985	[496]	[881,554,455,510]	1	hSpCas9	negative selection	7366960
18311386	18311409	11	-	27260156	MHHES1	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.2387018503567424	[807]	[927,1314,1201,878]	4	hSpCas9	negative selection	7366961
18311407	18311430	11	+	27260156	MHHES1	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.22944451098140228	[665]	[1022,1042,1053,501]	4	hSpCas9	negative selection	7431219
18310740	18310763	11	-	27260156	MHHES1	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.10273735901642489	[198]	[193,155,344,246]	2	hSpCas9	negative selection	7431220
18310850	18310873	11	-	27260156	MHHES1	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.14087663572763542	[1298]	[1256,1663,1216,1194]	-3	hSpCas9	negative selection	7431221
18305464	18305487	11	+	27260156	MEWO	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.22395742269871294	[473]	[522,445,585]	5	hSpCas9	negative selection	7488210
18305464	18305487	11	-	27260156	MEWO	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.20403625060817546	[496]	[623,312,316]	-4	hSpCas9	negative selection	7488211
18311386	18311409	11	-	27260156	MEWO	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.033478042997053814	[807]	[849,779,606]	0	hSpCas9	negative selection	7488212
18311407	18311430	11	+	27260156	MEWO	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.14248221356995316	[665]	[686,579,449]	-3	hSpCas9	negative selection	7552470
18310740	18310763	11	-	27260156	MEWO	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.543155730842898	[198]	[120,119,140]	-8	hSpCas9	negative selection	7552471
18310850	18310873	11	-	27260156	MEWO	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.11415061967861329	[1298]	[1390,964,1064]	-2	hSpCas9	negative selection	7552472
18305464	18305487	11	+	27260156	LNCAPCLONEFGC	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.027615969156186967	[473]	[508,276,520,464]	0	hSpCas9	negative selection	7609461
18305464	18305487	11	-	27260156	LNCAPCLONEFGC	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.3861877215020315	[496]	[393,304,375,308]	-5	hSpCas9	negative selection	7609462
18311386	18311409	11	-	27260156	LNCAPCLONEFGC	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.129071392212167	[807]	[748,602,577,735]	-2	hSpCas9	negative selection	7609463
18311407	18311430	11	+	27260156	LNCAPCLONEFGC	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.06532131150547682	[665]	[549,698,519,520]	-1	hSpCas9	negative selection	7673721
18310740	18310763	11	-	27260156	LNCAPCLONEFGC	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.6421990431538953	[198]	[92,81,151,142]	-7	hSpCas9	negative selection	7673722
18310850	18310873	11	-	27260156	LNCAPCLONEFGC	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.15025305611247886	[1298]	[1071,849,1334,1037]	-2	hSpCas9	negative selection	7673723
18305464	18305487	11	+	27260156	PANC0327	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.15910694089683197	[473]	[698,269,445,509]	2	hSpCas9	negative selection	7730712
18305464	18305487	11	-	27260156	PANC0327	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.18515844580307994	[496]	[418,424,404,301]	-3	hSpCas9	negative selection	7730713
18311386	18311409	11	-	27260156	PANC0327	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.36828513208458735	[807]	[578,444,487,727]	-5	hSpCas9	negative selection	7730714
18311407	18311430	11	+	27260156	PANC0327	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.07704558243163889	[665]	[400,375,670,805]	-1	hSpCas9	negative selection	7794972
18310740	18310763	11	-	27260156	PANC0327	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.35160213565866694	[198]	[294,216,224,171]	5	hSpCas9	negative selection	7794973
18310850	18310873	11	-	27260156	PANC0327	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.3097351295733515	[1298]	[1031,746,1127,848]	-4	hSpCas9	negative selection	7794974
18305464	18305487	11	+	27260156	NCIH2009	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.22902259713967307	[473]	[932,623,803]	3	hSpCas9	negative selection	7851963
18305464	18305487	11	-	27260156	NCIH2009	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.09275646164194966	[496]	[729,756,478]	-1	hSpCas9	negative selection	7851964
18311386	18311409	11	-	27260156	NCIH2009	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.08667236844753012	[807]	[1217,1262,1115]	1	hSpCas9	negative selection	7851965
18311407	18311430	11	+	27260156	NCIH2009	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.12380936038044432	[665]	[1174,946,950]	1	hSpCas9	negative selection	7916223
18310740	18310763	11	-	27260156	NCIH2009	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.2932879392487663	[198]	[327,287,403]	4	hSpCas9	negative selection	7916224
18310850	18310873	11	-	27260156	NCIH2009	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.1181028430187443	[1298]	[1902,1535,1622]	-2	hSpCas9	negative selection	7916225
18305464	18305487	11	+	27260156	NCIH1373	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.05049794954071303	[473]	[446,437,535,206]	0	hSpCas9	negative selection	7973214
18305464	18305487	11	-	27260156	NCIH1373	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.03077440441989309	[496]	[589,409,523,179]	0	hSpCas9	negative selection	7973215
18311386	18311409	11	-	27260156	NCIH1373	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.12770006080980922	[807]	[1259,788,1023,246]	1	hSpCas9	negative selection	7973216
18311407	18311430	11	+	27260156	NCIH1373	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.12361825429386142	[665]	[969,873,874,138]	1	hSpCas9	negative selection	8037474
18310740	18310763	11	-	27260156	NCIH1373	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.2834848019506718	[198]	[234,205,487,37]	2	hSpCas9	negative selection	8037475
18310850	18310873	11	-	27260156	NCIH1373	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.051069341555153525	[1298]	[1782,1240,1680,362]	0	hSpCas9	negative selection	8037476
18305464	18305487	11	+	27260156	PATU8902	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.8819223003441826	[473]	[787,1104,1184,1869]	8	hSpCas9	negative selection	8094465
18305464	18305487	11	-	27260156	PATU8902	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.05839075602147521	[496]	[716,550,591,1094]	0	hSpCas9	negative selection	8094466
18311386	18311409	11	-	27260156	PATU8902	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.020358764829663478	[807]	[1368,846,974,1439]	0	hSpCas9	negative selection	8094467
18311407	18311430	11	+	27260156	PATU8902	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.4338485181489191	[665]	[846,675,645,565]	-4	hSpCas9	negative selection	8158725
18310740	18310763	11	-	27260156	PATU8902	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.6042289009656445	[198]	[298,123,59,1411]	6	hSpCas9	negative selection	8158726
18310850	18310873	11	-	27260156	PATU8902	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.006416466577354285	[1298]	[1334,2643,1525,1835]	0	hSpCas9	negative selection	8158727
18305464	18305487	11	+	27260156	PANC1	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.6256032639420273	[473]	[629,755,643,516]	8	hSpCas9	negative selection	8215716
18305464	18305487	11	-	27260156	PANC1	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.45476242561663727	[496]	[839,536,562,404]	7	hSpCas9	negative selection	8215717
18311386	18311409	11	-	27260156	PANC1	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.2382219849990106	[807]	[830,984,584,880]	4	hSpCas9	negative selection	8215718
18311407	18311430	11	+	27260156	PANC1	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.33318545519339693	[665]	[697,890,767,573]	5	hSpCas9	negative selection	8279976
18310740	18310763	11	-	27260156	PANC1	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.24027319680250314	[198]	[120,201,163,107]	-4	hSpCas9	negative selection	8279977
18310850	18310873	11	-	27260156	PANC1	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.3285332123642608	[1298]	[1124,1743,1472,1327]	5	hSpCas9	negative selection	8279978
18305464	18305487	11	+	27260156	PANC0813	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.3317464310870182	[473]	[706,640,708,742]	5	hSpCas9	negative selection	8336967
18305464	18305487	11	-	27260156	PANC0813	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.05330113567074841	[496]	[536,646,588,478]	-1	hSpCas9	negative selection	8336968
18311386	18311409	11	-	27260156	PANC0813	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.02385002240414369	[807]	[966,845,1039,885]	0	hSpCas9	negative selection	8336969
18311407	18311430	11	+	27260156	PANC0813	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.033981874688478464	[665]	[972,688,853,707]	0	hSpCas9	negative selection	8401227
18310740	18310763	11	-	27260156	PANC0813	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.49025958148067794	[198]	[322,638,162,193]	7	hSpCas9	negative selection	8401228
18310850	18310873	11	-	27260156	PANC0813	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.051602753583689376	[1298]	[1618,1510,1498,1281]	-1	hSpCas9	negative selection	8401229
18305464	18305487	11	+	27260156	RDES	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.29110424951213903	[473]	[604,562,641,893]	5	hSpCas9	negative selection	8458218
18305464	18305487	11	-	27260156	RDES	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.1480542172411725	[496]	[433,447,620,582]	-2	hSpCas9	negative selection	8458219
18311386	18311409	11	-	27260156	RDES	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.25401289823112627	[807]	[716,753,749,903]	-4	hSpCas9	negative selection	8458220
18311407	18311430	11	+	27260156	RDES	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.037357516778644184	[665]	[629,679,799,1103]	0	hSpCas9	negative selection	8522478
18310740	18310763	11	-	27260156	RDES	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.34760757709898904	[198]	[94,234,212,186]	-5	hSpCas9	negative selection	8522479
18310850	18310873	11	-	27260156	RDES	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.09805273502817902	[1298]	[1268,1419,1361,1529]	-2	hSpCas9	negative selection	8522480
18305464	18305487	11	+	27260156	PC3	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.17322974507591293	[473]	[187,438,798,469]	-4	hSpCas9	negative selection	8579469
18305464	18305487	11	-	27260156	PC3	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.038517780311936214	[496]	[246,475,1105,516]	0	hSpCas9	negative selection	8579470
18311386	18311409	11	-	27260156	PC3	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.06115948394600035	[807]	[562,609,1095,968]	-1	hSpCas9	negative selection	8579471
18311407	18311430	11	+	27260156	PC3	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.08289295714858635	[665]	[484,484,1186,886]	2	hSpCas9	negative selection	8643729
18310740	18310763	11	-	27260156	PC3	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.0863833514912491	[198]	[184,186,181,263]	2	hSpCas9	negative selection	8643730
18310850	18310873	11	-	27260156	PC3	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.3118866829169449	[1298]	[824,821,1613,1120]	-6	hSpCas9	negative selection	8643731
18305464	18305487	11	+	27260156	PATU8988T	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.20111933395184728	[473]	[522,683,405,507]	3	hSpCas9	negative selection	8700720
18305464	18305487	11	-	27260156	PATU8988T	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.14802393830681615	[496]	[755,415,436,507]	2	hSpCas9	negative selection	8700721
18311386	18311409	11	-	27260156	PATU8988T	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.006703223966356697	[807]	[876,706,747,799]	0	hSpCas9	negative selection	8700722
18311407	18311430	11	+	27260156	PATU8988T	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.02635004481334996	[665]	[555,670,667,635]	0	hSpCas9	negative selection	8764980
18310740	18310763	11	-	27260156	PATU8988T	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.4229901650932577	[198]	[274,79,28,188]	-6	hSpCas9	negative selection	8764981
18310850	18310873	11	-	27260156	PATU8988T	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.10116502319754961	[1298]	[1321,1190,1059,1105]	-2	hSpCas9	negative selection	8764982
18305464	18305487	11	+	27260156	T47D	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.2744603598093469	[473]	[573,654,620,827]	6	hSpCas9	negative selection	8821971
18305464	18305487	11	-	27260156	T47D	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.13338369998120264	[496]	[619,609,606,707]	3	hSpCas9	negative selection	8821972
18311386	18311409	11	-	27260156	T47D	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.10646373221557126	[807]	[872,740,965,928]	-2	hSpCas9	negative selection	8821973
18311407	18311430	11	+	27260156	T47D	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.08607799677570882	[665]	[778,823,909,777]	1	hSpCas9	negative selection	8886231
18310740	18310763	11	-	27260156	T47D	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.060731771818340885	[198]	[241,237,171,236]	-1	hSpCas9	negative selection	8886232
18310850	18310873	11	-	27260156	T47D	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	0.048727797566985975	[1298]	[1596,1641,1469,1545]	1	hSpCas9	negative selection	8886233
18305464	18305487	11	+	27260156	SU8686	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.35490904996002737	[473]	[421,629,679,702]	6	hSpCas9	negative selection	8943222
18305464	18305487	11	-	27260156	SU8686	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.07925774889466798	[496]	[618,403,506,557]	1	hSpCas9	negative selection	8943223
18311386	18311409	11	-	27260156	SU8686	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	0.13537668492502852	[807]	[833,894,795,1009]	2	hSpCas9	negative selection	8943224
18311407	18311430	11	+	27260156	SU8686	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.04549984428270276	[665]	[568,644,813,518]	-1	hSpCas9	negative selection	9007482
18310740	18310763	11	-	27260156	SU8686	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	0.35988941483436243	[198]	[222,293,241,248]	6	hSpCas9	negative selection	9007483
18310850	18310873	11	-	27260156	SU8686	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.01682485526386568	[1298]	[970,1218,1372,1619]	0	hSpCas9	negative selection	9007484
18305464	18305487	11	+	27260156	SKES1	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.0621735046024897	[473]	[700,539,420,358]	1	hSpCas9	negative selection	9064473
18305464	18305487	11	-	27260156	SKES1	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.37761961136313044	[496]	[410,425,379,321]	-7	hSpCas9	negative selection	9064474
18311386	18311409	11	-	27260156	SKES1	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.1525081801010867	[807]	[893,728,665,638]	-3	hSpCas9	negative selection	9064475
18311407	18311430	11	+	27260156	SKES1	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.10225000208972612	[665]	[754,720,615,430]	-2	hSpCas9	negative selection	9128733
18310740	18310763	11	-	27260156	SKES1	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.30757974872483795	[198]	[187,158,189,111]	-6	hSpCas9	negative selection	9128734
18310850	18310873	11	-	27260156	SKES1	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.19191310163598096	[1298]	[1250,1355,961,1015]	-4	hSpCas9	negative selection	9128735
18305464	18305487	11	+	27260156	TOV112D	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.049855807526560963	[473]	[465,465,549,356]	-1	hSpCas9	negative selection	9185724
18305464	18305487	11	-	27260156	TOV112D	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.11900432983901911	[496]	[480,466,440,447]	-2	hSpCas9	negative selection	9185725
18311386	18311409	11	-	27260156	TOV112D	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.01792149753674943	[807]	[1318,594,612,665]	0	hSpCas9	negative selection	9185726
18311407	18311430	11	+	27260156	TOV112D	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.39524221498152934	[665]	[595,666,459,355]	-7	hSpCas9	negative selection	9249984
18310740	18310763	11	-	27260156	TOV112D	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.7514669892969388	[198]	[112,113,168,76]	-9	hSpCas9	negative selection	9249985
18310850	18310873	11	-	27260156	TOV112D	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.27510899134014744	[1298]	[904,990,1337,1030]	-5	hSpCas9	negative selection	9249986
18305464	18305487	11	+	27260156	TC71	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	0.11956362758325707	[473]	[537,427,624,618]	3	hSpCas9	negative selection	9306975
18305464	18305487	11	-	27260156	TC71	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.19190249148476868	[496]	[400,506,433,529]	-5	hSpCas9	negative selection	9306976
18311386	18311409	11	-	27260156	TC71	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.15533081717003483	[807]	[643,697,876,898]	-4	hSpCas9	negative selection	9306977
18311407	18311430	11	+	27260156	TC71	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	0.06572348378545534	[665]	[763,731,728,764]	1	hSpCas9	negative selection	9371235
18310740	18310763	11	-	27260156	TC71	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.26865347731281397	[198]	[131,144,200,233]	-6	hSpCas9	negative selection	9371236
18310850	18310873	11	-	27260156	TC71	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.09346687219881211	[1298]	[1230,1503,1233,1251]	-2	hSpCas9	negative selection	9371237
18305464	18305487	11	+	27260156	TC32	viability	CCAGCTGTATGATCATACTGAGG	HPS5	ENSG00000110756	-0.038219111557119156	[473]	[340,310,588,561]	0	hSpCas9	negative selection	9428226
18305464	18305487	11	-	27260156	TC32	viability	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.15796298902231737	[496]	[359,272,538,570]	-3	hSpCas9	negative selection	9428227
18311386	18311409	11	-	27260156	TC32	viability	ATTATGTTGCTGTAGCTACCAGG	HPS5	ENSG00000110756	-0.21607040919153686	[807]	[593,458,903,749]	-4	hSpCas9	negative selection	9428228
18311407	18311430	11	+	27260156	TC32	viability	ATCATCATCATGTAAACAACAGG	HPS5	ENSG00000110756	-0.038462608487354166	[665]	[579,505,794,592]	0	hSpCas9	negative selection	9492486
18310740	18310763	11	-	27260156	TC32	viability	CAATACTTCTAAACAAGCAAAGG	HPS5	ENSG00000110756	-0.018889013328545756	[198]	[134,153,268,202]	0	hSpCas9	negative selection	9492487
18310850	18310873	11	-	27260156	TC32	viability	TATGTGTCTTCAGAACACAAAGG	HPS5	ENSG00000110756	-0.040636292072565805	[1298]	[1067,935,1370,1457]	0	hSpCas9	negative selection	9492488
18296806	18296829	11	-	27869803	HPAFII	viability after 27 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.6939270719142361	[75]	[50,75,NaN]	5	hSpCas9	negative selection	9540840
18297666	18297689	11	-	27869803	HPAFII	viability after 27 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.3924215095751613	[109]	[94,59,NaN]	3	hSpCas9	negative selection	9540841
18305464	18305487	11	-	27869803	HPAFII	viability after 27 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.5796092662269494	[248]	[199,191,NaN]	5	hSpCas9	negative selection	9540842
18306234	18306257	11	-	27869803	HPAFII	viability after 27 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.19972730226834295	[281]	[163,99,NaN]	-1	hSpCas9	negative selection	9540843
18311995	18312018	11	-	27869803	HPAFII	viability after 27 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.9553636108892416	[359]	[360,371,NaN]	7	hSpCas9	negative selection	9540844
18317768	18317791	11	-	27869803	HPAFII	viability after 27 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.39681005401814384	[56]	[9,63,NaN]	3	hSpCas9	negative selection	9540845
18296806	18296829	11	-	27869803	HPAFII	viability after 15 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.5904261889263038	[75]	[130,117,NaN]	6	hSpCas9	negative selection	9623289
18297666	18297689	11	-	27869803	HPAFII	viability after 15 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	-0.1747344129175139	[109]	[121,93,NaN]	-2	hSpCas9	negative selection	9623290
18305464	18305487	11	-	27869803	HPAFII	viability after 15 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.3838517779428283	[248]	[490,260,NaN]	4	hSpCas9	negative selection	9623291
18306234	18306257	11	-	27869803	HPAFII	viability after 15 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.14798743534638673	[281]	[468,252,NaN]	1	hSpCas9	negative selection	9623292
18311995	18312018	11	-	27869803	HPAFII	viability after 15 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.7866859021600052	[359]	[828,566,NaN]	8	hSpCas9	negative selection	9623293
18317768	18317791	11	-	27869803	HPAFII	viability after 15 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.7277682944304531	[56]	[106,97,NaN]	7	hSpCas9	negative selection	9623294
18296806	18296829	11	-	27869803	ASPC1	viability after 36 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	-1.3134565573957029	[330]	[0,126,13]	-8	hSpCas9	negative selection	9705738
18297666	18297689	11	-	27869803	ASPC1	viability after 36 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.4003420221469619	[237]	[21,91,183]	4	hSpCas9	negative selection	9705739
18305464	18305487	11	-	27869803	ASPC1	viability after 36 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.5519093360392229	[489]	[548,169,102]	5	hSpCas9	negative selection	9705740
18306234	18306257	11	-	27869803	ASPC1	viability after 36 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.29267219116354326	[701]	[431,154,70]	-3	hSpCas9	negative selection	9705741
18311995	18312018	11	-	27869803	ASPC1	viability after 36 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.4328872370654515	[1084]	[535,545,460]	4	hSpCas9	negative selection	9705742
18317768	18317791	11	-	27869803	ASPC1	viability after 36 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	-0.5671056189743675	[136]	[0,79,15]	-5	hSpCas9	negative selection	9705743
18296806	18296829	11	-	27869803	PATU8988S	viability after 35 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.46851163390564365	[199]	[91,130,NaN]	5	hSpCas9	negative selection	9788187
18297666	18297689	11	-	27869803	PATU8988S	viability after 35 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	-0.5210597043711889	[261]	[87,58,NaN]	-5	hSpCas9	negative selection	9788188
18305464	18305487	11	-	27869803	PATU8988S	viability after 35 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.0782273240811717	[612]	[103,417,NaN]	0	hSpCas9	negative selection	9788189
18306234	18306257	11	-	27869803	PATU8988S	viability after 35 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.5808098175025644	[545]	[286,370,NaN]	6	hSpCas9	negative selection	9788190
18311995	18312018	11	-	27869803	PATU8988S	viability after 35 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.3447676864929963	[1003]	[520,505,NaN]	4	hSpCas9	negative selection	9788191
18317768	18317791	11	-	27869803	PATU8988S	viability after 35 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.6266308784921759	[114]	[75,66,NaN]	7	hSpCas9	negative selection	9788192
18296806	18296829	11	-	27869803	PATU8988S	viability after 31 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.71288401278908	[199]	[102,165,NaN]	8	hSpCas9	negative selection	9870636
18297666	18297689	11	-	27869803	PATU8988S	viability after 31 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	-0.8068968166036481	[261]	[42,80,NaN]	-7	hSpCas9	negative selection	9870637
18305464	18305487	11	-	27869803	PATU8988S	viability after 31 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	-0.18491585751964676	[612]	[141,307,NaN]	-2	hSpCas9	negative selection	9870638
18306234	18306257	11	-	27869803	PATU8988S	viability after 31 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.3556957396132258	[545]	[216,356,NaN]	4	hSpCas9	negative selection	9870639
18311995	18312018	11	-	27869803	PATU8988S	viability after 31 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.17966234310479456	[1003]	[408,509,NaN]	2	hSpCas9	negative selection	9870640
18317768	18317791	11	-	27869803	PATU8988S	viability after 31 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	-0.10505919356684545	[114]	[17,73,NaN]	-1	hSpCas9	negative selection	9870641
18296806	18296829	11	-	27869803	HPAFII	viability after 35 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	0.48301680099582045	[75]	[73,30,NaN]	3	hSpCas9	negative selection	9953085
18297666	18297689	11	-	27869803	HPAFII	viability after 35 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.4229939705516389	[109]	[100,44,NaN]	2	hSpCas9	negative selection	9953086
18305464	18305487	11	-	27869803	HPAFII	viability after 35 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.5842687015391139	[248]	[172,206,NaN]	4	hSpCas9	negative selection	9953087
18306234	18306257	11	-	27869803	HPAFII	viability after 35 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	-0.08793077610146172	[281]	[67,208,NaN]	0	hSpCas9	negative selection	9953088
18311995	18312018	11	-	27869803	HPAFII	viability after 35 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.8161141442349971	[359]	[191,465,NaN]	5	hSpCas9	negative selection	9953089
18317768	18317791	11	-	27869803	HPAFII	viability after 35 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	-0.25943803529648823	[56]	[1,48,NaN]	-2	hSpCas9	negative selection	9953090
18296806	18296829	11	-	27869803	HPAFII	viability after 31 days	GATCAGTGTTGTGGCTCACACGG	HPS5	ENSG00000110756	1.0869965682380074	[75]	[92,87,NaN]	7	hSpCas9	negative selection	10035534
18297666	18297689	11	-	27869803	HPAFII	viability after 31 days	GGAGCATTTGAAATCTCAGCTGG	HPS5	ENSG00000110756	0.2747718950010648	[109]	[89,57,NaN]	2	hSpCas9	negative selection	10035535
18305464	18305487	11	-	27869803	HPAFII	viability after 31 days	CCTCAGTATGATCATACAGCTGG	HPS5	ENSG00000110756	0.7750550662066387	[248]	[230,247,NaN]	5	hSpCas9	negative selection	10035536
18306234	18306257	11	-	27869803	HPAFII	viability after 31 days	CTGATATATTGTGCTCGCCCAGG	HPS5	ENSG00000110756	0.15336856303170962	[281]	[86,272,NaN]	1	hSpCas9	negative selection	10035537
18311995	18312018	11	-	27869803	HPAFII	viability after 31 days	GCATAGCTGTGTCTCGGAAATGG	HPS5	ENSG00000110756	0.8686320161861478	[359]	[310,431,NaN]	6	hSpCas9	negative selection	10035538
18317768	18317791	11	-	27869803	HPAFII	viability after 31 days	ATTACTCTCAGCCCTGCGGCTGG	HPS5	ENSG00000110756	0.30530509717550425	[56]	[28,50,NaN]	2	hSpCas9	negative selection	10035539
18306138	18306161	11	+	28162770	P31FUJ	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.20191766072616502	[272]	[368]	2	hSpCas9	negative selection	10171030
18291606	18291629	11	-	28162770	P31FUJ	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.9889995536422163	[348]	[813]	9	hSpCas9	negative selection	10171031
18291677	18291700	11	+	28162770	P31FUJ	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.2400793694367495	[164]	[228]	2	hSpCas9	negative selection	10171032
18283849	18283872	11	-	28162770	P31FUJ	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-3.491536472814547	[133]	[13]	-9	hSpCas9	negative selection	10171033
18281949	18281972	11	-	28162770	P31FUJ	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.1708744552711765	[113]	[118]	-2	hSpCas9	negative selection	10171034
18306237	18306260	11	+	28162770	P31FUJ	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.5299725761014327	[276]	[469]	6	hSpCas9	negative selection	10171035
18298853	18298876	11	-	28162770	P31FUJ	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.5588322595214588	[144]	[250]	6	hSpCas9	negative selection	10171036
18296797	18296820	11	-	28162770	P31FUJ	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.13916657297257926	[237]	[307]	1	hSpCas9	negative selection	10171037
18295083	18295106	11	-	28162770	P31FUJ	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.6541888337564351	[72]	[134]	7	hSpCas9	negative selection	10171038
18291723	18291746	11	+	28162770	P31FUJ	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.45678913676395705	[420]	[678]	5	hSpCas9	negative selection	10171039
18306138	18306161	11	+	28162770	TF1	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	NaN	[NaN]	[337]	1	hSpCas9	negative selection	10340396
18291606	18291629	11	-	28162770	TF1	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	NaN	[NaN]	[191]	1	hSpCas9	negative selection	10340397
18291677	18291700	11	+	28162770	TF1	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10340398
18283849	18283872	11	-	28162770	TF1	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10340399
18281949	18281972	11	-	28162770	TF1	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10340400
18306237	18306260	11	+	28162770	TF1	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10340401
18298853	18298876	11	-	28162770	TF1	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10340402
18296797	18296820	11	-	28162770	TF1	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10340403
18295083	18295106	11	-	28162770	TF1	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10340404
18291723	18291746	11	+	28162770	TF1	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	NaN	[NaN]	[522]	1	hSpCas9	negative selection	10340405
18306138	18306161	11	+	28162770	SKM1	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.02509356339951707	[98]	[171]	0	hSpCas9	negative selection	10509762
18291606	18291629	11	-	28162770	SKM1	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	-0.2440256276169562	[68]	[102]	-2	hSpCas9	negative selection	10509763
18291677	18291700	11	+	28162770	SKM1	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.27928163781517606	[54]	[117]	2	hSpCas9	negative selection	10509764
18283849	18283872	11	-	28162770	SKM1	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-5.7527390355848915	[60]	[1]	-9	hSpCas9	negative selection	10509765
18281949	18281972	11	-	28162770	SKM1	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.19637683129284916	[38]	[78]	2	hSpCas9	negative selection	10509766
18306237	18306260	11	+	28162770	SKM1	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.5413463242453377	[102]	[264]	5	hSpCas9	negative selection	10509767
18298853	18298876	11	-	28162770	SKM1	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	1.653083184926777	[24]	[138]	9	hSpCas9	negative selection	10509768
18296797	18296820	11	-	28162770	SKM1	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.9586852735735187	[38]	[133]	8	hSpCas9	negative selection	10509769
18295083	18295106	11	-	28162770	SKM1	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.15903668529957615	[11]	[18]	-1	hSpCas9	negative selection	10509770
18291723	18291746	11	+	28162770	SKM1	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.7125117800117928	[96]	[280]	6	hSpCas9	negative selection	10509771
18306138	18306161	11	+	28162770	SKM1	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.02509356339951707	[98]	[171]	0	hSpCas9	negative selection	10679128
18291606	18291629	11	-	28162770	SKM1	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	-0.2440256276169562	[68]	[102]	-2	hSpCas9	negative selection	10679129
18291677	18291700	11	+	28162770	SKM1	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.27928163781517606	[54]	[117]	2	hSpCas9	negative selection	10679130
18283849	18283872	11	-	28162770	SKM1	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-5.7527390355848915	[60]	[1]	-9	hSpCas9	negative selection	10679131
18281949	18281972	11	-	28162770	SKM1	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.19637683129284916	[38]	[78]	2	hSpCas9	negative selection	10679132
18306237	18306260	11	+	28162770	SKM1	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.5413463242453377	[102]	[264]	5	hSpCas9	negative selection	10679133
18298853	18298876	11	-	28162770	SKM1	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	1.653083184926777	[24]	[138]	9	hSpCas9	negative selection	10679134
18296797	18296820	11	-	28162770	SKM1	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.9586852735735187	[38]	[133]	8	hSpCas9	negative selection	10679135
18295083	18295106	11	-	28162770	SKM1	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.15903668529957615	[11]	[18]	-1	hSpCas9	negative selection	10679136
18291723	18291746	11	+	28162770	SKM1	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.7125117800117928	[96]	[280]	6	hSpCas9	negative selection	10679137
18306138	18306161	11	+	28162770	PL21	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.3303383376160217	[359]	[196]	3	hSpCas9	negative selection	10848494
18291606	18291629	11	-	28162770	PL21	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.1297502865979221	[188]	[89]	1	hSpCas9	negative selection	10848495
18291677	18291700	11	+	28162770	PL21	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.6602108673826677	[204]	[140]	6	hSpCas9	negative selection	10848496
18283849	18283872	11	-	28162770	PL21	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-4.754056695897556	[185]	[2]	-9	hSpCas9	negative selection	10848497
18281949	18281972	11	-	28162770	PL21	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-1.2372656978179781	[129]	[23]	-7	hSpCas9	negative selection	10848498
18306237	18306260	11	+	28162770	PL21	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.06360078154155457	[298]	[135]	0	hSpCas9	negative selection	10848499
18298853	18298876	11	-	28162770	PL21	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	1.1139829707396058	[68]	[64]	8	hSpCas9	negative selection	10848500
18296797	18296820	11	-	28162770	PL21	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.357240575574049	[112]	[62]	3	hSpCas9	negative selection	10848501
18295083	18295106	11	-	28162770	PL21	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.38482288623183614	[35]	[11]	-3	hSpCas9	negative selection	10848502
18291723	18291746	11	+	28162770	PL21	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.37571117907277474	[424]	[239]	3	hSpCas9	negative selection	10848503
18306138	18306161	11	+	28162770	P31FUJ	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.20191766072616502	[272]	[368]	2	hSpCas9	negative selection	11017860
18291606	18291629	11	-	28162770	P31FUJ	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.9889995536422163	[348]	[813]	9	hSpCas9	negative selection	11017861
18291677	18291700	11	+	28162770	P31FUJ	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.2400793694367495	[164]	[228]	2	hSpCas9	negative selection	11017862
18283849	18283872	11	-	28162770	P31FUJ	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-3.491536472814547	[133]	[13]	-9	hSpCas9	negative selection	11017863
18281949	18281972	11	-	28162770	P31FUJ	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.1708744552711765	[113]	[118]	-2	hSpCas9	negative selection	11017864
18306237	18306260	11	+	28162770	P31FUJ	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.5299725761014327	[276]	[469]	6	hSpCas9	negative selection	11017865
18298853	18298876	11	-	28162770	P31FUJ	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.5588322595214588	[144]	[250]	6	hSpCas9	negative selection	11017866
18296797	18296820	11	-	28162770	P31FUJ	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.13916657297257926	[237]	[307]	1	hSpCas9	negative selection	11017867
18295083	18295106	11	-	28162770	P31FUJ	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.6541888337564351	[72]	[134]	7	hSpCas9	negative selection	11017868
18291723	18291746	11	+	28162770	P31FUJ	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.45678913676395705	[420]	[678]	5	hSpCas9	negative selection	11017869
18306138	18306161	11	+	28162770	OCIAML5	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.14002823105065676	[182]	[363]	1	hSpCas9	negative selection	11187226
18291606	18291629	11	-	28162770	OCIAML5	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.7295524867827887	[143]	[430]	6	hSpCas9	negative selection	11187227
18291677	18291700	11	+	28162770	OCIAML5	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.16352766670029056	[102]	[165]	-1	hSpCas9	negative selection	11187228
18283849	18283872	11	-	28162770	OCIAML5	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-4.454102584944094	[84]	[6]	-9	hSpCas9	negative selection	11187229
18281949	18281972	11	-	28162770	OCIAML5	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.2917661243771099	[58]	[86]	-2	hSpCas9	negative selection	11187230
18306237	18306260	11	+	28162770	OCIAML5	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	-0.2245794534962839	[155]	[240]	-2	hSpCas9	negative selection	11187231
18298853	18298876	11	-	28162770	OCIAML5	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.670035906018583	[85]	[246]	6	hSpCas9	negative selection	11187232
18296797	18296820	11	-	28162770	OCIAML5	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	1.070627702968554	[114]	[435]	8	hSpCas9	negative selection	11187233
18295083	18295106	11	-	28162770	OCIAML5	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.17399466575135936	[54]	[87]	-1	hSpCas9	negative selection	11187234
18291723	18291746	11	+	28162770	OCIAML5	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.3862673943414723	[269]	[636]	3	hSpCas9	negative selection	11187235
18306138	18306161	11	+	28162770	EOL1	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.6876955937168115	[693]	[226]	-5	hSpCas9	negative selection	11356592
18291606	18291629	11	-	28162770	EOL1	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.6786375435279497	[267]	[225]	6	hSpCas9	negative selection	11356593
18291677	18291700	11	+	28162770	EOL1	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.2619426678036674	[333]	[210]	2	hSpCas9	negative selection	11356594
18283849	18283872	11	-	28162770	EOL1	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-5.043542980474721	[312]	[4]	-9	hSpCas9	negative selection	11356595
18281949	18281972	11	-	28162770	EOL1	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.6473585763251752	[219]	[73]	-5	hSpCas9	negative selection	11356596
18306237	18306260	11	+	28162770	EOL1	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.20264962549327004	[507]	[307]	1	hSpCas9	negative selection	11356597
18298853	18298876	11	-	28162770	EOL1	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.3500776446670206	[136]	[91]	3	hSpCas9	negative selection	11356598
18296797	18296820	11	-	28162770	EOL1	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	-0.9592592109249427	[154]	[41]	-6	hSpCas9	negative selection	11356599
18295083	18295106	11	-	28162770	EOL1	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.4072957921819107	[72]	[28]	-3	hSpCas9	negative selection	11356600
18291723	18291746	11	+	28162770	EOL1	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.5865513080555187	[473]	[374]	5	hSpCas9	negative selection	11356601
18306138	18306161	11	+	28162770	MOLM13	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.09690706234367041	[515]	[398]	0	hSpCas9	negative selection	11525958
18291606	18291629	11	-	28162770	MOLM13	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.7143272768476777	[305]	[362]	5	hSpCas9	negative selection	11525959
18291677	18291700	11	+	28162770	MOLM13	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.412101603358832	[289]	[278]	3	hSpCas9	negative selection	11525960
18283849	18283872	11	-	28162770	MOLM13	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-6.7415639840843715	[295]	[1]	-9	hSpCas9	negative selection	11525961
18281949	18281972	11	-	28162770	MOLM13	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.22775537782086386	[149]	[126]	1	hSpCas9	negative selection	11525962
18306237	18306260	11	+	28162770	MOLM13	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.6463041058204242	[432]	[489]	5	hSpCas9	negative selection	11525963
18298853	18298876	11	-	28162770	MOLM13	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.6106295536606609	[124]	[137]	4	hSpCas9	negative selection	11525964
18296797	18296820	11	-	28162770	MOLM13	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.7864188999700763	[254]	[317]	6	hSpCas9	negative selection	11525965
18295083	18295106	11	-	28162770	MOLM13	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.43393022451651775	[70]	[37]	-3	hSpCas9	negative selection	11525966
18291723	18291746	11	+	28162770	MOLM13	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.4678893815445788	[612]	[612]	3	hSpCas9	negative selection	11525967
18306138	18306161	11	+	28162770	HEL	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.7168979426504785	[454]	[478]	6	hSpCas9	negative selection	11695324
18291606	18291629	11	-	28162770	HEL	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.06826870509684299	[273]	[183]	0	hSpCas9	negative selection	11695325
18291677	18291700	11	+	28162770	HEL	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.6562853638383047	[211]	[213]	5	hSpCas9	negative selection	11695326
18283849	18283872	11	-	28162770	HEL	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-3.3987378039758025	[246]	[14]	-9	hSpCas9	negative selection	11695327
18281949	18281972	11	-	28162770	HEL	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.2958163576461251	[130]	[102]	2	hSpCas9	negative selection	11695328
18306237	18306260	11	+	28162770	HEL	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.5284061565213621	[419]	[387]	4	hSpCas9	negative selection	11695329
18298853	18298876	11	-	28162770	HEL	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	1.2628907611838132	[107]	[165]	9	hSpCas9	negative selection	11695330
18296797	18296820	11	-	28162770	HEL	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.5060501600319766	[176]	[160]	4	hSpCas9	negative selection	11695331
18295083	18295106	11	-	28162770	HEL	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.20216624061437538	[75]	[55]	1	hSpCas9	negative selection	11695332
18291723	18291746	11	+	28162770	HEL	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.6194422120892188	[436]	[429]	5	hSpCas9	negative selection	11695333
18306138	18306161	11	+	28162770	MV411	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	0.33463599268464483	[320]	[340]	3	hSpCas9	negative selection	11864690
18291606	18291629	11	-	28162770	MV411	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	1.1230772124068542	[223]	[410]	8	hSpCas9	negative selection	11864691
18291677	18291700	11	+	28162770	MV411	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.06421572672700529	[217]	[191]	0	hSpCas9	negative selection	11864692
18283849	18283872	11	-	28162770	MV411	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-5.359892762966835	[194]	[3]	-9	hSpCas9	negative selection	11864693
18281949	18281972	11	-	28162770	MV411	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.6624750500616192	[95]	[127]	6	hSpCas9	negative selection	11864694
18306237	18306260	11	+	28162770	MV411	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	1.0394745274426571	[256]	[444]	8	hSpCas9	negative selection	11864695
18298853	18298876	11	-	28162770	MV411	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	-0.4795439548108087	[95]	[57]	-4	hSpCas9	negative selection	11864696
18296797	18296820	11	-	28162770	MV411	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.5068241796014248	[131]	[157]	4	hSpCas9	negative selection	11864697
18295083	18295106	11	-	28162770	MV411	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-1.5958369455297712	[60]	[16]	-7	hSpCas9	negative selection	11864698
18291723	18291746	11	+	28162770	MV411	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.16128090703306075	[413]	[389]	1	hSpCas9	negative selection	11864699
18306138	18306161	11	+	28162770	MONOMAC1	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.06579231378130124	[293]	[321]	0	hSpCas9	negative selection	12034056
18291606	18291629	11	-	28162770	MONOMAC1	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.9775951570602864	[135]	[306]	8	hSpCas9	negative selection	12034057
18291677	18291700	11	+	28162770	MONOMAC1	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.22560599925632446	[101]	[99]	-2	hSpCas9	negative selection	12034058
18283849	18283872	11	-	28162770	MONOMAC1	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-1.8100137239503065	[103]	[33]	-8	hSpCas9	negative selection	12034059
18281949	18281972	11	-	28162770	MONOMAC1	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.41177239561597034	[79]	[121]	4	hSpCas9	negative selection	12034060
18306237	18306260	11	+	28162770	MONOMAC1	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.08200543497463231	[238]	[289]	0	hSpCas9	negative selection	12034061
18298853	18298876	11	-	28162770	MONOMAC1	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.9567684890194819	[79]	[177]	8	hSpCas9	negative selection	12034062
18296797	18296820	11	-	28162770	MONOMAC1	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.7766518758245992	[82]	[162]	7	hSpCas9	negative selection	12034063
18295083	18295106	11	-	28162770	MONOMAC1	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-1.247662920129522	[28]	[13]	-7	hSpCas9	negative selection	12034064
18291723	18291746	11	+	28162770	MONOMAC1	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	0.19821804002875276	[256]	[337]	2	hSpCas9	negative selection	12034065
18306138	18306161	11	+	28162770	OCIAML2	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.24533751339991838	[70]	[331]	-2	hSpCas9	negative selection	12203422
18291606	18291629	11	-	28162770	OCIAML2	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.8743818827582425	[30]	[314]	8	hSpCas9	negative selection	12203423
18291677	18291700	11	+	28162770	OCIAML2	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	0.8661460340525144	[28]	[292]	8	hSpCas9	negative selection	12203424
18283849	18283872	11	-	28162770	OCIAML2	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-3.2689959640725106	[39]	[22]	-9	hSpCas9	negative selection	12203425
18281949	18281972	11	-	28162770	OCIAML2	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	-0.07303746042272669	[25]	[136]	0	hSpCas9	negative selection	12203426
18306237	18306260	11	+	28162770	OCIAML2	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.6957285611799588	[44]	[403]	6	hSpCas9	negative selection	12203427
18298853	18298876	11	-	28162770	OCIAML2	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	0.8512982696452014	[8]	[89]	8	hSpCas9	negative selection	12203428
18296797	18296820	11	-	28162770	OCIAML2	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.6289058483087533	[20]	[179]	6	hSpCas9	negative selection	12203429
18295083	18295106	11	-	28162770	OCIAML2	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	0.04394334758759677	[13]	[79]	0	hSpCas9	negative selection	12203430
18291723	18291746	11	+	28162770	OCIAML2	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	-0.055592325963317535	[80]	[431]	0	hSpCas9	negative selection	12203431
18306138	18306161	11	+	28162770	OCIAML3	viability	AGAGTAATCACAGGGAGAGGTGG	HPS5	ENSG00000110756	-0.17517856188294534	[94]	[253]	-1	hSpCas9	negative selection	12372788
18291606	18291629	11	-	28162770	OCIAML3	viability	TCTAAGATCAAAAGCACCAGTGG	HPS5	ENSG00000110756	0.7279204545631992	[53]	[269]	6	hSpCas9	negative selection	12372789
18291677	18291700	11	+	28162770	OCIAML3	viability	GTTCCGAAGACCACTTGCAATGG	HPS5	ENSG00000110756	-0.3033304794212406	[55]	[136]	-2	hSpCas9	negative selection	12372790
18283849	18283872	11	-	28162770	OCIAML3	viability	GGAGCTGGAGAGAAGAAGAGAGG	HPS5	ENSG00000110756	-4.05343925896146	[54]	[9]	-9	hSpCas9	negative selection	12372791
18281949	18281972	11	-	28162770	OCIAML3	viability	GGATTGCTGAGAAAAGGCAGAGG	HPS5	ENSG00000110756	0.65974895192162	[25]	[123]	6	hSpCas9	negative selection	12372792
18306237	18306260	11	+	28162770	OCIAML3	viability	GGGCGAGCACAATATATCAGAGG	HPS5	ENSG00000110756	0.3773421549190912	[88]	[348]	3	hSpCas9	negative selection	12372793
18298853	18298876	11	-	28162770	OCIAML3	viability	GTGGAACGCCTGCTAAGAAGAGG	HPS5	ENSG00000110756	-0.07943446749440519	[20]	[59]	0	hSpCas9	negative selection	12372794
18296797	18296820	11	-	28162770	OCIAML3	viability	TGTGGCTCACACGGAAATGAAGG	HPS5	ENSG00000110756	0.7453025327914357	[32]	[166]	6	hSpCas9	negative selection	12372795
18295083	18295106	11	-	28162770	OCIAML3	viability	AAAGTGAGACCAGAGCTCAGGGG	HPS5	ENSG00000110756	-0.5115454801321901	[16]	[35]	-4	hSpCas9	negative selection	12372796
18291723	18291746	11	+	28162770	OCIAML3	viability	AGGTCATCCAAAGACTCCCTTGG	HPS5	ENSG00000110756	-0.851658849461054	[106]	[178]	-6	hSpCas9	negative selection	12372797