Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3028
• Symbol: HSD17B10
• Description: hydroxysteroid 17-beta dehydrogenase 10

DataSource: http://genomecrispr.dkfz.de/#!/results/HSD17B10

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
53433861	53433884	X	-	26472758	Jiyoye	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-1.2602492794072555	[161]	[50]	-7	hSpCas9	negative selection	74337
53433710	53433733	X	+	26472758	Jiyoye	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-1.3221770285504575	[62]	[18]	-7	hSpCas9	negative selection	74338
53433788	53433811	X	+	26472758	Jiyoye	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-2.2329926212387368	[585]	[93]	-8	hSpCas9	negative selection	74339
53432378	53432401	X	-	26472758	Jiyoye	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-1.3789942106611028	[168]	[48]	-7	hSpCas9	negative selection	74340
53432315	53432338	X	-	26472758	Jiyoye	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.723023341620828	[196]	[44]	-8	hSpCas9	negative selection	74341
53432043	53432066	X	-	26472758	Jiyoye	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-1.469089250071882	[267]	[72]	-7	hSpCas9	negative selection	74342
53433774	53433797	X	-	26472758	Jiyoye	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-1.7627496199364392	[35]	[7]	-8	hSpCas9	negative selection	74343
53432270	53432293	X	-	26472758	Jiyoye	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.8879526540377736	[399]	[162]	-6	hSpCas9	negative selection	74344
53432065	53432088	X	+	26472758	Jiyoye	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.762749619936439	[98]	[21]	-8	hSpCas9	negative selection	74345
53431829	53431852	X	+	26472758	Jiyoye	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.4803498892357136	[258]	[69]	-7	hSpCas9	negative selection	74346
53433861	53433884	X	-	26472758	KBM7	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-3.455699640491083	[892,512]	[39,19]	-9	hSpCas9	negative selection	265455
53433710	53433733	X	+	26472758	KBM7	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.440758983368527	[362,305]	[40,17]	-9	hSpCas9	negative selection	265456
53433788	53433811	X	+	26472758	KBM7	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-3.5106832553808127	[1145,1069]	[68,24]	-9	hSpCas9	negative selection	265457
53432378	53432401	X	-	26472758	KBM7	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-3.0153230899782146	[735,859]	[46,46]	-9	hSpCas9	negative selection	265458
53432315	53432338	X	-	26472758	KBM7	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.1439696058147812	[527,360]	[53,39]	-8	hSpCas9	negative selection	265459
53432043	53432066	X	-	26472758	KBM7	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.469352637314087	[919,679]	[100,36]	-9	hSpCas9	negative selection	265460
53433774	53433797	X	-	26472758	KBM7	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.33620404389456704	[122,172]	[30,78]	-3	hSpCas9	negative selection	265461
53432270	53432293	X	-	26472758	KBM7	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.4437225995916195	[1259,1162]	[510,336]	-4	hSpCas9	negative selection	265462
53432065	53432088	X	+	26472758	KBM7	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.155433964454515	[395,241]	[65,65]	-7	hSpCas9	negative selection	265463
53431829	53431852	X	+	26472758	KBM7	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.646876497558643	[456,380]	[78,47]	-8	hSpCas9	negative selection	265464
53433861	53433884	X	-	26472758	Raji	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-1.0777278698833888	[381]	[41]	-7	hSpCas9	negative selection	456573
53433710	53433733	X	+	26472758	Raji	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-0.6768877735709636	[123]	[17]	-5	hSpCas9	negative selection	456574
53433788	53433811	X	+	26472758	Raji	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-0.9926636414767307	[402]	[46]	-6	hSpCas9	negative selection	456575
53432378	53432401	X	-	26472758	Raji	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-1.194506806277218	[285]	[28]	-7	hSpCas9	negative selection	456576
53432315	53432338	X	-	26472758	Raji	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.7226914631840882	[191]	[26]	-5	hSpCas9	negative selection	456577
53432043	53432066	X	-	26472758	Raji	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-1.9706189766276736	[455]	[26]	-8	hSpCas9	negative selection	456578
53433774	53433797	X	-	26472758	Raji	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.40163011211425803	[73]	[12]	-3	hSpCas9	negative selection	456579
53432270	53432293	X	-	26472758	Raji	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.11326122367658131	[549]	[117]	-1	hSpCas9	negative selection	456580
53432065	53432088	X	+	26472758	Raji	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.1974710461548215	[167]	[16]	-7	hSpCas9	negative selection	456581
53431829	53431852	X	+	26472758	Raji	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-0.2670119794078984	[279]	[53]	-2	hSpCas9	negative selection	456582
53433861	53433884	X	-	26472758	K562	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-2.8132967701898406	[407]	[48]	-8	hSpCas9	negative selection	647691
53433710	53433733	X	+	26472758	K562	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.9871453395682517	[262]	[27]	-8	hSpCas9	negative selection	647692
53433788	53433811	X	+	26472758	K562	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-3.4235995127822676	[1143]	[89]	-8	hSpCas9	negative selection	647693
53432378	53432401	X	-	26472758	K562	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.6385786616310796	[508]	[68]	-8	hSpCas9	negative selection	647694
53432315	53432338	X	-	26472758	K562	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.4303903904371902	[264]	[82]	-6	hSpCas9	negative selection	647695
53432043	53432066	X	-	26472758	K562	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-3.0267560667562807	[781]	[80]	-8	hSpCas9	negative selection	647696
53433774	53433797	X	-	26472758	K562	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-1.7080529022509672	[208]	[53]	-7	hSpCas9	negative selection	647697
53432270	53432293	X	-	26472758	K562	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-1.1973491372269187	[689]	[253]	-6	hSpCas9	negative selection	647698
53432065	53432088	X	+	26472758	K562	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-3.122698140987171	[226]	[21]	-8	hSpCas9	negative selection	647699
53431829	53431852	X	+	26472758	K562	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.7298509972401355	[388]	[98]	-7	hSpCas9	negative selection	647700
53431401	53431424	X	+	26627737	DLD1	viability	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.47450805845763516	[552]	[285,247,193]	5	hSpCas9	negative selection	846039
53431508	53431531	X	-	26627737	DLD1	viability	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.6671220904411934	[184]	[21,80,11]	-6	hSpCas9	negative selection	846040
53431872	53431895	X	-	26627737	DLD1	viability	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-3.2674890727797488	[857]	[0,27,50]	-9	hSpCas9	negative selection	846041
53432080	53432103	X	-	26627737	DLD1	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.24307190361648517	[407]	[92,134,97]	-3	hSpCas9	negative selection	846042
53432315	53432338	X	-	26627737	DLD1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.821453613787732	[934]	[52,2,62]	-9	hSpCas9	negative selection	846043
53433862	53433885	X	+	26627737	DLD1	viability	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-1.1246341503752688	[619]	[139,91,41]	-7	hSpCas9	negative selection	846044
53431401	53431424	X	+	26627737	GBM cells	viability after 5 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.6101655731041591	[316]	[253,264]	8	hSpCas9	negative selection	928354
53431508	53431531	X	-	26627737	GBM cells	viability after 5 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.5494647172344187	[85]	[51,82]	7	hSpCas9	negative selection	928355
53431872	53431895	X	-	26627737	GBM cells	viability after 5 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	0.10140673878442874	[364]	[198,220]	1	hSpCas9	negative selection	928356
53432080	53432103	X	-	26627737	GBM cells	viability after 5 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.04217092586591786	[181]	[81,118]	0	hSpCas9	negative selection	928357
53432315	53432338	X	-	26627737	GBM cells	viability after 5 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.3499066717284074	[403]	[166,172]	-5	hSpCas9	negative selection	928358
53433862	53433885	X	+	26627737	GBM cells	viability after 5 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.32233942673829424	[210]	[67,112]	-5	hSpCas9	negative selection	928359
53431401	53431424	X	+	26627737	GBM cells	viability after 13 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	1.1869847946647798	[316]	[411,374]	9	hSpCas9	negative selection	1010669
53431508	53431531	X	-	26627737	GBM cells	viability after 13 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	1.1253487537914577	[85]	[103,99]	9	hSpCas9	negative selection	1010670
53431872	53431895	X	-	26627737	GBM cells	viability after 13 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.508878013099483	[364]	[222,70]	-6	hSpCas9	negative selection	1010671
53432080	53432103	X	-	26627737	GBM cells	viability after 13 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.1686287785303992	[181]	[94,123]	2	hSpCas9	negative selection	1010672
53432315	53432338	X	-	26627737	GBM cells	viability after 13 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.141190565259885	[403]	[52,46]	-9	hSpCas9	negative selection	1010673
53433862	53433885	X	+	26627737	GBM cells	viability after 13 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.4974445392043693	[210]	[138,33]	-5	hSpCas9	negative selection	1010674
53431401	53431424	X	+	26627737	GBM cells	viability after 21 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	1.4226367511761273	[316]	[480,443]	9	hSpCas9	negative selection	1092984
53431508	53431531	X	-	26627737	GBM cells	viability after 21 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.843994156184331	[85]	[86,80]	8	hSpCas9	negative selection	1092985
53431872	53431895	X	-	26627737	GBM cells	viability after 21 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.2112315941856746	[364]	[93,77]	-7	hSpCas9	negative selection	1092986
53432080	53432103	X	-	26627737	GBM cells	viability after 21 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.3713111134112367	[181]	[141,114]	4	hSpCas9	negative selection	1092987
53432315	53432338	X	-	26627737	GBM cells	viability after 21 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.382610663997426	[403]	[19,21]	-9	hSpCas9	negative selection	1092988
53433862	53433885	X	+	26627737	GBM cells	viability after 21 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.8877041395527783	[210]	[62,60]	-6	hSpCas9	negative selection	1092989
53431401	53431424	X	+	26627737	RPE1	viability after 9 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	-0.22063833492645046	[2219]	[664,507]	-1	hSpCas9	negative selection	1175299
53431508	53431531	X	-	26627737	RPE1	viability after 9 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.20116567603054392	[761]	[337,191]	1	hSpCas9	negative selection	1175300
53431872	53431895	X	-	26627737	RPE1	viability after 9 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	0.9538513573408858	[1065]	[683,597]	6	hSpCas9	negative selection	1175301
53432080	53432103	X	-	26627737	RPE1	viability after 9 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	1.4594316186372973	[212]	[92,299]	7	hSpCas9	negative selection	1175302
53432315	53432338	X	-	26627737	RPE1	viability after 9 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.859678114948467	[1684]	[102,199]	-8	hSpCas9	negative selection	1175303
53433862	53433885	X	+	26627737	RPE1	viability after 9 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.47126050098035893	[1036]	[200,276]	-3	hSpCas9	negative selection	1175304
53431401	53431424	X	+	26627737	RPE1	viability after 12 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.24743121948281543	[2219]	[657,760]	1	hSpCas9	negative selection	1257614
53431508	53431531	X	-	26627737	RPE1	viability after 12 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.07868693702710372	[761]	[290,136]	0	hSpCas9	negative selection	1257615
53431872	53431895	X	-	26627737	RPE1	viability after 12 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	0.07693383893304967	[1065]	[355,244]	0	hSpCas9	negative selection	1257616
53432080	53432103	X	-	26627737	RPE1	viability after 12 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.08196732395289485	[212]	[11,111]	0	hSpCas9	negative selection	1257617
53432315	53432338	X	-	26627737	RPE1	viability after 12 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.6235905865073934	[1684]	[211,77]	-8	hSpCas9	negative selection	1257618
53433862	53433885	X	+	26627737	RPE1	viability after 12 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.19101360144291255	[1036]	[194,295]	-1	hSpCas9	negative selection	1257619
53431401	53431424	X	+	26627737	RPE1	viability after 15 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.22787549414622488	[2219]	[822,650]	1	hSpCas9	negative selection	1339929
53431508	53431531	X	-	26627737	RPE1	viability after 15 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-1.204829317985397	[761]	[120,66]	-6	hSpCas9	negative selection	1339930
53431872	53431895	X	-	26627737	RPE1	viability after 15 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.03420769374910165	[1065]	[407,184]	0	hSpCas9	negative selection	1339931
53432080	53432103	X	-	26627737	RPE1	viability after 15 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	1.225756999488016	[212]	[32,244]	7	hSpCas9	negative selection	1339932
53432315	53432338	X	-	26627737	RPE1	viability after 15 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.6081214541714914	[1684]	[248,66]	-7	hSpCas9	negative selection	1339933
53433862	53433885	X	+	26627737	RPE1	viability after 15 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.5790794155263344	[1036]	[175,215]	-4	hSpCas9	negative selection	1339934
53431401	53431424	X	+	26627737	RPE1	viability after 18 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	-0.1378435127487736	[2219]	[544,543]	-1	hSpCas9	negative selection	1422244
53431508	53431531	X	-	26627737	RPE1	viability after 18 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.8657981159420682	[761]	[151,70]	-5	hSpCas9	negative selection	1422245
53431872	53431895	X	-	26627737	RPE1	viability after 18 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.5843584300283942	[1065]	[187,195]	-4	hSpCas9	negative selection	1422246
53432080	53432103	X	-	26627737	RPE1	viability after 18 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.6978621382819363	[212]	[41,147]	4	hSpCas9	negative selection	1422247
53432315	53432338	X	-	26627737	RPE1	viability after 18 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.9302596468941542	[1684]	[142,93]	-8	hSpCas9	negative selection	1422248
53433862	53433885	X	+	26627737	RPE1	viability after 18 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.05531678567920412	[1036]	[205,336]	0	hSpCas9	negative selection	1422249
53431401	53431424	X	+	26627737	HeLa	viability after 8 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	3.882111353182159	[41]	[526,348,7]	9	hSpCas9	negative selection	1504559
53431508	53431531	X	-	26627737	HeLa	viability after 8 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.14323970818676307	[253]	[114,221,33]	1	hSpCas9	negative selection	1504560
53431872	53431895	X	-	26627737	HeLa	viability after 8 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.1144111879460705	[817]	[168,127,194]	-8	hSpCas9	negative selection	1504561
53432080	53432103	X	-	26627737	HeLa	viability after 8 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.8658774898486502	[176]	[205,184,50]	7	hSpCas9	negative selection	1504562
53432315	53432338	X	-	26627737	HeLa	viability after 8 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.27084886434733146	[440]	[137,78,248]	-3	hSpCas9	negative selection	1504563
53433862	53433885	X	+	26627737	HeLa	viability after 8 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.8553139524752734	[263]	[146,327,139]	7	hSpCas9	negative selection	1504564
53431401	53431424	X	+	26627737	HeLa	viability after 12 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	4.002387860184345	[41]	[482,159,209]	9	hSpCas9	negative selection	1586874
53431508	53431531	X	-	26627737	HeLa	viability after 12 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.039390205541955714	[253]	[111,89,105]	0	hSpCas9	negative selection	1586875
53431872	53431895	X	-	26627737	HeLa	viability after 12 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.2770836529820508	[817]	[75,201,131]	-8	hSpCas9	negative selection	1586876
53432080	53432103	X	-	26627737	HeLa	viability after 12 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.4566721695275944	[176]	[167,110,22]	4	hSpCas9	negative selection	1586877
53432315	53432338	X	-	26627737	HeLa	viability after 12 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.0650031129983089	[440]	[211,48,7]	-7	hSpCas9	negative selection	1586878
53433862	53433885	X	+	26627737	HeLa	viability after 12 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.3567144925784451	[263]	[7,132,274]	3	hSpCas9	negative selection	1586879
53431401	53431424	X	+	26627737	HeLa	viability after 15 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	3.151133294253696	[41]	[11,226,223]	9	hSpCas9	negative selection	1669189
53431508	53431531	X	-	26627737	HeLa	viability after 15 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.9609052004255922	[253]	[177,298,120]	7	hSpCas9	negative selection	1669190
53431872	53431895	X	-	26627737	HeLa	viability after 15 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.593448364283343	[817]	[52,165,112]	-8	hSpCas9	negative selection	1669191
53432080	53432103	X	-	26627737	HeLa	viability after 15 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.0064126316771691005	[176]	[96,8,113]	0	hSpCas9	negative selection	1669192
53432315	53432338	X	-	26627737	HeLa	viability after 15 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-5.577542643559869	[440]	[8,0,0]	-9	hSpCas9	negative selection	1669193
53433862	53433885	X	+	26627737	HeLa	viability after 15 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.8660609449999681	[263]	[167,127,299]	6	hSpCas9	negative selection	1669194
53431401	53431424	X	+	26627737	HeLa	viability after 18 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	3.188626048820499	[41]	[6,198,223]	9	hSpCas9	negative selection	1751504
53431508	53431531	X	-	26627737	HeLa	viability after 18 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.9940682595670713	[253]	[124,251,120]	7	hSpCas9	negative selection	1751505
53431872	53431895	X	-	26627737	HeLa	viability after 18 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.5570993241846405	[817]	[38,139,112]	-8	hSpCas9	negative selection	1751506
53432080	53432103	X	-	26627737	HeLa	viability after 18 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.03837959534018087	[176]	[66,8,113]	0	hSpCas9	negative selection	1751507
53432315	53432338	X	-	26627737	HeLa	viability after 18 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-5.375576749435343	[440]	[6,0,0]	-9	hSpCas9	negative selection	1751508
53433862	53433885	X	+	26627737	HeLa	viability after 18 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.8504060437562384	[263]	[106,107,299]	6	hSpCas9	negative selection	1751509
53431401	53431424	X	+	26627737	HCT116	viability after 6 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.2409764277687049	[656]	[288,29]	1	hSpCas9	negative selection	1833819
53431508	53431531	X	-	26627737	HCT116	viability after 6 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-1.7792568900104624	[341]	[34,4]	-7	hSpCas9	negative selection	1833820
53431872	53431895	X	-	26627737	HCT116	viability after 6 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	1.1009610889097678	[1116]	[288,424]	6	hSpCas9	negative selection	1833821
53432080	53432103	X	-	26627737	HCT116	viability after 6 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	1.1399569214982805	[540]	[296,126]	6	hSpCas9	negative selection	1833822
53432315	53432338	X	-	26627737	HCT116	viability after 6 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	0.518240352388105	[610]	[56,181]	3	hSpCas9	negative selection	1833823
53433862	53433885	X	+	26627737	HCT116	viability after 6 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.40667614987341894	[1001]	[115,259]	2	hSpCas9	negative selection	1833824
53431401	53431424	X	+	26627737	HCT116	viability after 8 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	-0.07330129842852848	[272]	[223,196,10]	-1	hSpCas9	negative selection	1916134
53431508	53431531	X	-	26627737	HCT116	viability after 8 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.16845490309405442	[144]	[75,91,100]	2	hSpCas9	negative selection	1916135
53431872	53431895	X	-	26627737	HCT116	viability after 8 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	0.25732453364607855	[315]	[167,275,179]	3	hSpCas9	negative selection	1916136
53432080	53432103	X	-	26627737	HCT116	viability after 8 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.7200201158329027	[347]	[125,72,149]	-7	hSpCas9	negative selection	1916137
53432315	53432338	X	-	26627737	HCT116	viability after 8 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.3506352013303218	[490]	[50,46,60]	-9	hSpCas9	negative selection	1916138
53433862	53433885	X	+	26627737	HCT116	viability after 8 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.44799280168821803	[232]	[104,229,188]	5	hSpCas9	negative selection	1916139
53431401	53431424	X	+	26627737	HCT116	viability after 9 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.38086393733712975	[656]	[457,46]	3	hSpCas9	negative selection	1998449
53431508	53431531	X	-	26627737	HCT116	viability after 9 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-1.344382564545275	[341]	[21,46]	-7	hSpCas9	negative selection	1998450
53431872	53431895	X	-	26627737	HCT116	viability after 9 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.29561115552406536	[1116]	[242,242]	-2	hSpCas9	negative selection	1998451
53432080	53432103	X	-	26627737	HCT116	viability after 9 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.08894475915909597	[540]	[189,92]	0	hSpCas9	negative selection	1998452
53432315	53432338	X	-	26627737	HCT116	viability after 9 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.59659611875695	[610]	[31,22]	-9	hSpCas9	negative selection	1998453
53433862	53433885	X	+	26627737	HCT116	viability after 9 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.7014634925109876	[1001]	[233,593]	5	hSpCas9	negative selection	1998454
53431401	53431424	X	+	26627737	HCT116	viability after 12 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.5610469990501877	[272]	[186,204,244]	5	hSpCas9	negative selection	2080764
53431508	53431531	X	-	26627737	HCT116	viability after 12 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.5553979266879929	[144]	[90,37,206]	5	hSpCas9	negative selection	2080765
53431872	53431895	X	-	26627737	HCT116	viability after 12 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.6887173305788042	[315]	[123,92,89]	-6	hSpCas9	negative selection	2080766
53432080	53432103	X	-	26627737	HCT116	viability after 12 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.5686729181054039	[347]	[203,88,68]	-6	hSpCas9	negative selection	2080767
53432315	53432338	X	-	26627737	HCT116	viability after 12 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.20991722982523	[490]	[86,31,44]	-9	hSpCas9	negative selection	2080768
53433862	53433885	X	+	26627737	HCT116	viability after 12 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.32231228260984285	[232]	[48,175,243]	3	hSpCas9	negative selection	2080769
53431401	53431424	X	+	26627737	HCT116	viability after 15 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	-0.28103609746000957	[272]	[13,138,218]	-3	hSpCas9	negative selection	2163079
53431508	53431531	X	-	26627737	HCT116	viability after 15 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.6069745037287633	[144]	[154,108,119]	5	hSpCas9	negative selection	2163080
53431872	53431895	X	-	26627737	HCT116	viability after 15 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.5203656176263948	[315]	[98,131,144]	-5	hSpCas9	negative selection	2163081
53432080	53432103	X	-	26627737	HCT116	viability after 15 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.9292241144318953	[347]	[178,50,93]	-7	hSpCas9	negative selection	2163082
53432315	53432338	X	-	26627737	HCT116	viability after 15 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.454431881826597	[490]	[93,53,11]	-9	hSpCas9	negative selection	2163083
53433862	53433885	X	+	26627737	HCT116	viability after 15 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.02188344263142078	[232]	[127,91,185]	0	hSpCas9	negative selection	2163084
53431401	53431424	X	+	26627737	HCT116	viability after 18 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	-0.07656120176704712	[272]	[210,16,155]	0	hSpCas9	negative selection	2245394
53431508	53431531	X	-	26627737	HCT116	viability after 18 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.024935850170260343	[144]	[74,20,115]	0	hSpCas9	negative selection	2245395
53431872	53431895	X	-	26627737	HCT116	viability after 18 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.5691830739520636	[315]	[90,21,42]	-8	hSpCas9	negative selection	2245396
53432080	53432103	X	-	26627737	HCT116	viability after 18 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-1.2173712087971413	[347]	[106,32,79]	-8	hSpCas9	negative selection	2245397
53432315	53432338	X	-	26627737	HCT116	viability after 18 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.910651742839715	[490]	[39,16,38]	-9	hSpCas9	negative selection	2245398
53433862	53433885	X	+	26627737	HCT116	viability after 18 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.09174694043677833	[232]	[34,155,168]	0	hSpCas9	negative selection	2245399
53432597	53432620	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCACTTTGGGAGGCCGAGG	HSD17B10	ENSG00000072506	0.17643232981432222	[5,22]	[1,4]	0	dCas9-VP64	positive selection	2447766
53432597	53432620	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCACTTTGGGAGGCCGAGG	HSD17B10	ENSG00000072506	-1.1255792224366725	[173,43]	[24,6]	-9	dCas9-VP64	positive selection	2543021
53432334	53432357	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	-0.17833239396782363	[4,4]	[3,3]	-3	hSpCas9	positive selection	2994248
53432315	53432338	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.3699638533032357	[3,3]	[0,2]	-5	hSpCas9	positive selection	2994249
53432318	53432341	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	-1.0146492416943813	[3,4]	[2,0]	-9	hSpCas9	positive selection	2994250
53432386	53432409	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.38213186550996836	[4,5]	[1,3]	-5	hSpCas9	positive selection	2994251
53432334	53432357	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	-0.07512442252845894	[4,4]	[2,2]	-1	hSpCas9	positive selection	3062106
53432315	53432338	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.5025636566364711	[3,3]	[0,1]	-7	hSpCas9	positive selection	3062107
53432318	53432341	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	-0.3053246699265783	[3,3]	[2,1]	-4	hSpCas9	positive selection	3062108
53432386	53432409	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.7798876019478624	[4,4]	[2,0]	-9	hSpCas9	positive selection	3062109
53432264	53432287		+	24336571	A375	resistance to PLX after 7 days	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	0.1719928280579931	[24,22]	[26,27]	5	hSpCas9	positive selection	3119870
53433818	53433841		+	24336571	A375	resistance to PLX after 7 days	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	1.1850005390656881	[8,10]	[20,24]	9	hSpCas9	positive selection	3119871
53432326	53432349		-	24336571	A375	resistance to PLX after 7 days	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	0.4962309485636175	[19,18]	[25,27]	9	hSpCas9	positive selection	3119872
53433820	53433843		-	24336571	A375	resistance to PLX after 7 days	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	1.0808202019604045	[3,3]	[9,8]	9	hSpCas9	positive selection	3119873
53432264	53432287		+	24336571	A375	resistance to PLX after 14 days	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	0.26740195988298954	[22,20]	[11,11]	2	hSpCas9	positive selection	3177663
53433818	53433841		+	24336571	A375	resistance to PLX after 14 days	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	0.7977788967616897	[4,7]	[4,4]	6	hSpCas9	positive selection	3177664
53432326	53432349		-	24336571	A375	resistance to PLX after 14 days	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	0.5406120565862443	[11,15]	[7,10]	5	hSpCas9	positive selection	3177665
53433820	53433843		-	24336571	A375	resistance to PLX after 14 days	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	0.6018364518437267	[1,2]	[1,1]	5	hSpCas9	positive selection	3177666
53432264	53432287		+	24336571	A375	viability after 7 days	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	0.09319664309210884	[23]	[24,22]	1	hSpCas9	negative selection	3235456
53433818	53433841		+	24336571	A375	viability after 7 days	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.5330628806604625	[30]	[8,10]	-9	hSpCas9	negative selection	3235457
53432326	53432349		-	24336571	A375	viability after 7 days	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	-0.8197880776609069	[35]	[19,18]	-8	hSpCas9	negative selection	3235458
53433820	53433843		-	24336571	A375	viability after 7 days	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.194853103942028	[10]	[3,3]	-9	hSpCas9	negative selection	3235459
53432264	53432287		+	24336571	A375	viability after 14 days	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	-0.03550129723862416	[23]	[22,20]	0	hSpCas9	negative selection	3293249
53433818	53433841		+	24336571	A375	viability after 14 days	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-2.154282749099764	[30]	[4,7]	-9	hSpCas9	negative selection	3293250
53432326	53432349		-	24336571	A375	viability after 14 days	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	-1.27664019533196	[35]	[11,15]	-9	hSpCas9	negative selection	3293251
53433820	53433843		-	24336571	A375	viability after 14 days	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.7261935488209346	[10]	[1,2]	-9	hSpCas9	negative selection	3293252
53431859	53431882	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-1.3201026165899135	[381,381]	[0,0]	-8	hSpCas9	positive selection	3373345
53432240	53432263	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.2425196756373702	[180,180]	[0,0]	-1	hSpCas9	positive selection	3373346
53432017	53432040	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.086969696469982	[324,324]	[0,0]	-7	hSpCas9	positive selection	3373347
53432333	53432356	X	+	26780180	HT29	viability (Avana library 4 designs)	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	7.09876743334361	[]	[]	9	hSpCas9	negative selection	3431546
53432315	53432338	X	-	26780180	HT29	viability (Avana library 4 designs)	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	6.40885510223531	[]	[]	9	hSpCas9	negative selection	3431547
53432318	53432341	X	-	26780180	HT29	viability (Avana library 4 designs)	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	3.40723483308894	[]	[]	8	hSpCas9	negative selection	3431548
53432385	53432408	X	+	26780180	HT29	viability (Avana library 4 designs)	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	4.76871250345298	[]	[]	9	hSpCas9	negative selection	3431549
53432333	53432356	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	-14.5818888616271	[]	[]	-9	hSpCas9	negative selection	3517248
53432385	53432408	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-10.3939809934941	[]	[]	-8	hSpCas9	negative selection	3517249
53432315	53432338	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-8.62037104157606	[]	[]	-7	hSpCas9	negative selection	3517250
53432318	53432341	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	2.15177510461366	[]	[]	3	hSpCas9	negative selection	3517251
53432270	53432293	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	2.58639763715892	[]	[]	4	hSpCas9	negative selection	3517252
53433862	53433885	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	4.17810171542831	[]	[]	7	hSpCas9	negative selection	3517253
53432333	53432356	X	+	26780180	A375	viability (Avana lentiGuide)	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	22.7964529185873	[]	[]	9	hSpCas9	negative selection	3625907
53432385	53432408	X	+	26780180	A375	viability (Avana lentiGuide)	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	16.137436200594	[]	[]	8	hSpCas9	negative selection	3625908
53432315	53432338	X	-	26780180	A375	viability (Avana lentiGuide)	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	22.2115932693069	[]	[]	9	hSpCas9	negative selection	3625909
53432318	53432341	X	-	26780180	A375	viability (Avana lentiGuide)	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	11.2372386129474	[]	[]	7	hSpCas9	negative selection	3625910
53432270	53432293	X	-	26780180	A375	viability (Avana lentiGuide)	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	23.889303836693	[]	[]	9	hSpCas9	negative selection	3625911
53433862	53433885	X	+	26780180	A375	viability (Avana lentiGuide)	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	12.4632916755314	[]	[]	7	hSpCas9	negative selection	3625912
53432333	53432356	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	-0.08429622075227247	[6]	[5,5]	-1	hSpCas9	positive selection	3734566
53432385	53432408	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.05318653245040511	[6]	[6,5]	-1	hSpCas9	positive selection	3734567
53432315	53432338	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	0.1345215313609042	[4]	[5,4]	3	hSpCas9	positive selection	3734568
53432318	53432341	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	0.29477865817141435	[5]	[6,6]	8	hSpCas9	positive selection	3734569
53432270	53432293	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	0.216890631627919	[4]	[5,4]	6	hSpCas9	positive selection	3734570
53433862	53433885	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.2909642826228276	[6]	[7,7]	8	hSpCas9	positive selection	3734571
53432333	53432356	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTGACAGCTACATCCACACGG	HSD17B10	ENSG00000072506	-0.12260885159962431	[7]	[4,5]	-2	hSpCas9	positive selection	3843173
53432385	53432408	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.30487580718768537	[7]	[5,3]	-4	hSpCas9	positive selection	3843174
53432315	53432338	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.037306554270286	[5]	[1,1]	-8	hSpCas9	positive selection	3843175
53432318	53432341	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCAACTGTGCAGGCATCGCGG	HSD17B10	ENSG00000072506	0.13670338187142372	[5]	[4,6]	3	hSpCas9	positive selection	3843176
53432270	53432293	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	0.025211210983071886	[4]	[3,4]	0	hSpCas9	positive selection	3843177
53433862	53433885	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.21714112377238676	[6]	[7,6]	5	hSpCas9	positive selection	3843178
53432080	53432103	X	-	26780180	A375	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	1.71574544127597	[]	[]	9	hSpCas9	negative selection	3949223
53431859	53431882	X	+	26780180	A375	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	1.51800061610198	[]	[]	8	hSpCas9	negative selection	3949224
53433818	53433841	X	+	26780180	A375	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	2.29288502265823	[]	[]	9	hSpCas9	negative selection	3949225
53432240	53432263	X	+	26780180	A375	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	1.75802488665207	[]	[]	9	hSpCas9	negative selection	3949226
53433820	53433843	X	-	26780180	A375	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	1.89718154848597	[]	[]	9	hSpCas9	negative selection	3949227
53432017	53432040	X	+	26780180	A375	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	2.12436028018041	[]	[]	9	hSpCas9	negative selection	3949228
53432080	53432103	X	-	26780180	HT29	viability (GeCKOv2 library)	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	1.99121990757999	[]	[]	9	hSpCas9	negative selection	4057189
53431859	53431882	X	+	26780180	HT29	viability (GeCKOv2 library)	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	1.64389640183142	[]	[]	8	hSpCas9	negative selection	4057190
53433818	53433841	X	+	26780180	HT29	viability (GeCKOv2 library)	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	3.00736128345723	[]	[]	9	hSpCas9	negative selection	4057191
53432240	53432263	X	+	26780180	HT29	viability (GeCKOv2 library)	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	1.36229934299157	[]	[]	7	hSpCas9	negative selection	4057192
53433820	53433843	X	-	26780180	HT29	viability (GeCKOv2 library)	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	2.20442400126901	[]	[]	9	hSpCas9	negative selection	4057193
53432017	53432040	X	+	26780180	HT29	viability (GeCKOv2 library)	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	2.53953773847732	[]	[]	9	hSpCas9	negative selection	4057194
53432264	53432287	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	0.11136496907553833	[4]	[3,3]	3	hSpCas9	positive selection	4143431
53433818	53433841	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.13678966848492166	[4]	[2,2]	-3	hSpCas9	positive selection	4143432
53432326	53432349	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	-0.05220383115839086	[4]	[2,3]	-1	hSpCas9	positive selection	4143433
53433820	53433843	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.6036009704968511	[3]	[2,0]	-9	hSpCas9	positive selection	4143434
53432264	53432287	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCTTCCAAGGTATGGGTCTGG	HSD17B10	ENSG00000072506	0.2740388029116291	[4]	[2,2,5,0]	2	hSpCas9	positive selection	4207453
53433818	53433841	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.5535802498985475	[4]	[0,2,0,0]	-7	hSpCas9	positive selection	4207454
53432326	53432349	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGTAGCTGTCAACTGTGCAGG	HSD17B10	ENSG00000072506	0.6608070081157748	[4]	[0,2,2,3]	4	hSpCas9	positive selection	4207455
53433820	53433843	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.3416381120085432	[2]	[0,0,1,0]	-5	hSpCas9	positive selection	4207456
53433820	53433843	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.04002972291601833	[2]	[2,1]	-1	hSpCas9	positive selection	4275851
53433818	53433841	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.03702025832082874	[3]	[2,2]	0	hSpCas9	positive selection	4275852
53432080	53432103	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.29994731515316203	[3]	[3,3]	6	hSpCas9	positive selection	4275853
53431859	53431882	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	0.6428070265847404	[4]	[4,6]	9	hSpCas9	positive selection	4340111
53432240	53432263	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.004846215327776515	[3]	[3,2]	0	hSpCas9	positive selection	4340112
53432017	53432040	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	0.2375000033624668	[4]	[4,3]	5	hSpCas9	positive selection	4340113
53432348	53432370	X	-	27760321	OCIAML3	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.3960616136280418	[457,365]	[391,459]	5	hSpCas9	negative selection	4408118
53432365	53432387	X	-	27760321	OCIAML3	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-0.5410824318336576	[360,298]	[107,265]	-5	hSpCas9	negative selection	4408119
53432386	53432408	X	+	27760321	OCIAML3	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.6701123330429966	[608,539]	[277,286]	-6	hSpCas9	negative selection	4408120
53433709	53433731	X	+	27760321	OCIAML3	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-1.0034258963177023	[1054,885]	[275,508]	-7	hSpCas9	negative selection	4408121
53433772	53433794	X	-	27760321	OCIAML3	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-1.6230904711908922	[951,831]	[205,251]	-8	hSpCas9	negative selection	4408122
53432348	53432370	X	-	27760321	OCIAML2	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.3141898398627841	[457,365]	[335,511]	4	hSpCas9	negative selection	4491581
53432365	53432387	X	-	27760321	OCIAML2	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-1.0449753025427313	[360,298]	[114,146]	-7	hSpCas9	negative selection	4491582
53432386	53432408	X	+	27760321	OCIAML2	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-1.6244918855894586	[608,539]	[121,187]	-8	hSpCas9	negative selection	4491583
53433709	53433731	X	+	27760321	OCIAML2	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.5616924255245104	[1054,885]	[446,638]	-6	hSpCas9	negative selection	4491584
53433772	53433794	X	-	27760321	OCIAML2	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-2.6827493057750407	[951,831]	[71,164]	-9	hSpCas9	negative selection	4491585
53432348	53432370	X	-	27760321	MV411	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-0.5149184617350842	[457,365]	[129,277]	-4	hSpCas9	negative selection	4575044
53432365	53432387	X	-	27760321	MV411	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-1.0775097940448801	[360,298]	[19,226]	-6	hSpCas9	negative selection	4575045
53432386	53432408	X	+	27760321	MV411	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-2.2138694189445958	[608,539]	[63,107]	-8	hSpCas9	negative selection	4575046
53433709	53433731	X	+	27760321	MV411	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.5794535481135487	[1054,885]	[346,546]	-4	hSpCas9	negative selection	4575047
53433772	53433794	X	-	27760321	MV411	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-1.151512632783358	[951,831]	[241,297]	-6	hSpCas9	negative selection	4575048
53432348	53432370	X	-	27760321	HL60	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.11837468851394356	[457,365]	[302,426]	1	hSpCas9	negative selection	4658507
53432365	53432387	X	-	27760321	HL60	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-1.0235355315987862	[360,298]	[115,148]	-7	hSpCas9	negative selection	4658508
53432386	53432408	X	+	27760321	HL60	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-1.4399698637327032	[608,539]	[211,130]	-8	hSpCas9	negative selection	4658509
53433709	53433731	X	+	27760321	HL60	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.558652231281479	[1054,885]	[491,582]	-6	hSpCas9	negative selection	4658510
53433772	53433794	X	-	27760321	HL60	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-1.7107371532391242	[951,831]	[291,147]	-9	hSpCas9	negative selection	4658511
53432348	53432370	X	-	27760321	HT1080	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-7.021020557141388	[365,285]	[0,0]	-9	hSpCas9	negative selection	4741970
53432365	53432387	X	-	27760321	HT1080	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-6.7304197883806935	[298,233]	[0,0]	-9	hSpCas9	negative selection	4741971
53432386	53432408	X	+	27760321	HT1080	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-7.019178897361625	[539,421]	[0,1]	-9	hSpCas9	negative selection	4741972
53433709	53433731	X	+	27760321	HT1080	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-7.689547639572761	[885,691]	[1,0]	-9	hSpCas9	negative selection	4741973
53433772	53433794	X	-	27760321	HT1080	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-4.899247815996112	[831,648]	[17,0]	-8	hSpCas9	negative selection	4741974
53432348	53432370	X	-	27760321	HT29	viability after 7 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.2679553703428218	[365,285]	[692,364,482]	4	hSpCas9	negative selection	4825433
53432365	53432387	X	-	27760321	HT29	viability after 7 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	0.21348270820922613	[298,233]	[408,381,401]	3	hSpCas9	negative selection	4825434
53432386	53432408	X	+	27760321	HT29	viability after 7 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.2448449406217881	[539,421]	[750,460,389]	-4	hSpCas9	negative selection	4825435
53433709	53433731	X	+	27760321	HT29	viability after 7 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.7571374071571829	[885,691]	[656,584,566]	-8	hSpCas9	negative selection	4825436
53433772	53433794	X	-	27760321	HT29	viability after 7 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	0.08390800766607298	[831,648]	[1244,1048,772]	1	hSpCas9	negative selection	4825437
53432348	53432370	X	-	27760321	HT29	viability after 25 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-1.1489181099000785	[365,285]	[129,97,290]	-7	hSpCas9	negative selection	4908896
53432365	53432387	X	-	27760321	HT29	viability after 25 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-4.010339726317933	[298,233]	[15,37,0]	-9	hSpCas9	negative selection	4908897
53432386	53432408	X	+	27760321	HT29	viability after 25 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-2.8440327671767687	[539,421]	[77,35,119]	-8	hSpCas9	negative selection	4908898
53433709	53433731	X	+	27760321	HT29	viability after 25 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-3.1369393246236177	[885,691]	[171,105,15]	-8	hSpCas9	negative selection	4908899
53433772	53433794	X	-	27760321	HT29	viability after 25 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-5.406576873142146	[831,648]	[44,3,7]	-9	hSpCas9	negative selection	4908900
53432348	53432370	X	-	27760321	HT29	viability after 22 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-0.36703128672879115	[365,285]	[317,266,290]	-4	hSpCas9	negative selection	4992359
53432365	53432387	X	-	27760321	HT29	viability after 22 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-2.9382355452978604	[298,233]	[88,19,9]	-8	hSpCas9	negative selection	4992360
53432386	53432408	X	+	27760321	HT29	viability after 22 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-3.8882450473782137	[539,421]	[7,11,93]	-9	hSpCas9	negative selection	4992361
53433709	53433731	X	+	27760321	HT29	viability after 22 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-3.178196934629505	[885,691]	[93,54,153]	-8	hSpCas9	negative selection	4992362
53433772	53433794	X	-	27760321	HT29	viability after 22 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-4.76306960132087	[831,648]	[46,31,14]	-9	hSpCas9	negative selection	4992363
53432348	53432370	X	-	27760321	HT29	viability after 19 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-0.13133642610962673	[365,285]	[409,188,425]	-1	hSpCas9	negative selection	5075822
53432365	53432387	X	-	27760321	HT29	viability after 19 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-2.389925866128018	[298,233]	[65,43,64]	-8	hSpCas9	negative selection	5075823
53432386	53432408	X	+	27760321	HT29	viability after 19 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-2.355470999709718	[539,421]	[109,166,47]	-8	hSpCas9	negative selection	5075824
53433709	53433731	X	+	27760321	HT29	viability after 19 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-1.6429978244893317	[885,691]	[421,127,328]	-7	hSpCas9	negative selection	5075825
53433772	53433794	X	-	27760321	HT29	viability after 19 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-4.263068718824364	[831,648]	[66,31,35]	-9	hSpCas9	negative selection	5075826
53432348	53432370	X	-	27760321	HT29	viability after 16 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-0.3080319472985964	[365,285]	[452,133,315]	-3	hSpCas9	negative selection	5159285
53432365	53432387	X	-	27760321	HT29	viability after 16 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-0.6424080160686261	[298,233]	[275,157,147]	-6	hSpCas9	negative selection	5159286
53432386	53432408	X	+	27760321	HT29	viability after 16 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-1.0021854451487777	[539,421]	[422,99,301]	-7	hSpCas9	negative selection	5159287
53433709	53433731	X	+	27760321	HT29	viability after 16 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-1.8363721441873597	[885,691]	[317,294,133]	-8	hSpCas9	negative selection	5159288
53433772	53433794	X	-	27760321	HT29	viability after 16 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-1.9722257302946242	[831,648]	[206,248,175]	-8	hSpCas9	negative selection	5159289
53432348	53432370	X	-	27760321	HT29	viability after 13 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.3777476450893824	[365,285]	[495,653,333]	5	hSpCas9	negative selection	5242748
53432365	53432387	X	-	27760321	HT29	viability after 13 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-0.5207902752241964	[298,233]	[317,175,155]	-5	hSpCas9	negative selection	5242749
53432386	53432408	X	+	27760321	HT29	viability after 13 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-0.23141358781779447	[539,421]	[647,428,355]	-3	hSpCas9	negative selection	5242750
53433709	53433731	X	+	27760321	HT29	viability after 13 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.9802086550650303	[885,691]	[426,585,383]	-7	hSpCas9	negative selection	5242751
53433772	53433794	X	-	27760321	HT29	viability after 13 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	0.21427348215856146	[831,648]	[1125,1032,839]	2	hSpCas9	negative selection	5242752
53432348	53432370	X	-	27760321	HT29	viability after 10 days	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	0.12682214223083904	[365,285]	[457,391,480]	1	hSpCas9	negative selection	5326211
53432365	53432387	X	-	27760321	HT29	viability after 10 days	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	0.04821002765593524	[298,233]	[488,233,306]	0	hSpCas9	negative selection	5326212
53432386	53432408	X	+	27760321	HT29	viability after 10 days	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	0.3063631074821467	[539,421]	[725,870,636]	4	hSpCas9	negative selection	5326213
53433709	53433731	X	+	27760321	HT29	viability after 10 days	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-0.6085902638596684	[885,691]	[740,739,463]	-6	hSpCas9	negative selection	5326214
53433772	53433794	X	-	27760321	HT29	viability after 10 days	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	0.1546262614610061	[831,648]	[1072,1125,893]	2	hSpCas9	negative selection	5326215
53432348	53432370	X	-	27760321	MOLM13	viability	AAAGGAAAGTTTGGCCGTGTGG	HSD17B10	ENSG00000072506	-0.43140754268244835	[457,365]	[253,100]	-3	hSpCas9	negative selection	5409674
53432365	53432387	X	-	27760321	MOLM13	viability	CAGCTCTGGCTCTAGCAAAAGG	HSD17B10	ENSG00000072506	-1.7626563409803553	[360,298]	[99,15]	-7	hSpCas9	negative selection	5409675
53432386	53432408	X	+	27760321	MOLM13	viability	GTTTGCACATCCTTCTCAGAGG	HSD17B10	ENSG00000072506	-1.8213708178974697	[608,539]	[83,97]	-7	hSpCas9	negative selection	5409676
53433709	53433731	X	+	27760321	MOLM13	viability	TGACCCCACTTACGTCGGCTGG	HSD17B10	ENSG00000072506	-2.362579361836314	[1054,885]	[185,37]	-8	hSpCas9	negative selection	5409677
53433772	53433794	X	-	27760321	MOLM13	viability	GACCTGCCCAACTCGGGTGGGG	HSD17B10	ENSG00000072506	-2.2525646336048557	[951,831]	[59,143]	-8	hSpCas9	negative selection	5409678
53433820	53433843	X	-	27260156	BXPC3	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.6440906950906363	[412]	[252,326,239,282]	-8	hSpCas9	negative selection	5548311
53433818	53433841	X	+	27260156	BXPC3	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.9929010987767348	[634]	[364,291,300,377]	-9	hSpCas9	negative selection	5548312
53432080	53432103	X	-	27260156	BXPC3	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.06336588428185824	[597]	[505,642,838,638]	1	hSpCas9	negative selection	5548313
53431859	53431882	X	+	27260156	BXPC3	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.13535839233482339	[1196]	[1052,1002,1166,1373]	-3	hSpCas9	negative selection	5612571
53432240	53432263	X	+	27260156	BXPC3	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.8688484616982914	[725]	[282,432,440,530]	-9	hSpCas9	negative selection	5612572
53432017	53432040	X	+	27260156	BXPC3	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.7632000996799903	[1345]	[718,817,917,875]	-9	hSpCas9	negative selection	5612573
53433820	53433843	X	-	27260156	A673	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.1652483047755826	[412]	[417,478,416,450]	-4	hSpCas9	negative selection	5669562
53433818	53433841	X	+	27260156	A673	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.3162779356111324	[634]	[658,537,634,623]	-7	hSpCas9	negative selection	5669563
53432080	53432103	X	-	27260156	A673	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.08383346537272868	[597]	[841,727,809,666]	2	hSpCas9	negative selection	5669564
53431859	53431882	X	+	27260156	A673	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.1438572343558362	[1196]	[1377,1222,1159,1460]	-4	hSpCas9	negative selection	5733822
53432240	53432263	X	+	27260156	A673	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.5375013631331157	[725]	[655,583,600,564]	-8	hSpCas9	negative selection	5733823
53432017	53432040	X	+	27260156	A673	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.5234606264144882	[1345]	[1283,945,1221,1061]	-8	hSpCas9	negative selection	5733824
53433820	53433843	X	-	27260156	A375	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-2.3230728932616103	[412]	[117,130,79,64]	-9	hSpCas9	negative selection	5790813
53433818	53433841	X	+	27260156	A375	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-2.334953934150257	[634]	[183,165,43,190]	-9	hSpCas9	negative selection	5790814
53432080	53432103	X	-	27260156	A375	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.2649794697096444	[597]	[585,923,394,477]	-4	hSpCas9	negative selection	5790815
53431859	53431882	X	+	27260156	A375	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-1.4897259381442949	[1196]	[428,411,767,381]	-9	hSpCas9	negative selection	5855073
53432240	53432263	X	+	27260156	A375	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.1916051161008352	[725]	[327,451,495,234]	-8	hSpCas9	negative selection	5855074
53432017	53432040	X	+	27260156	A375	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.3670538600426019	[1345]	[798,501,483,633]	-9	hSpCas9	negative selection	5855075
53433820	53433843	X	-	27260156	COLO741	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.17572875184711995	[412]	[527,444,434]	-4	hSpCas9	negative selection	5912064
53433818	53433841	X	+	27260156	COLO741	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.6449781123155032	[634]	[546,620,398]	-8	hSpCas9	negative selection	5912065
53432080	53432103	X	-	27260156	COLO741	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.3873774031616982	[597]	[1112,1012,887]	7	hSpCas9	negative selection	5912066
53431859	53431882	X	+	27260156	COLO741	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.16931563917722636	[1196]	[1601,1425,1089]	-4	hSpCas9	negative selection	5976324
53432240	53432263	X	+	27260156	COLO741	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.7442305816388959	[725]	[637,613,424]	-9	hSpCas9	negative selection	5976325
53432017	53432040	X	+	27260156	COLO741	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.5296805740240763	[1345]	[1404,1090,1099]	-8	hSpCas9	negative selection	5976326
53433820	53433843	X	-	27260156	CAL120	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.2064495769781036	[412]	[290,203,183]	-9	hSpCas9	negative selection	6033315
53433818	53433841	X	+	27260156	CAL120	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.6338044935925509	[634]	[212,372,172]	-9	hSpCas9	negative selection	6033316
53432080	53432103	X	-	27260156	CAL120	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.2380585561110249	[597]	[781,1115,722]	3	hSpCas9	negative selection	6033317
53431859	53431882	X	+	27260156	CAL120	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.7103575666268169	[1196]	[1024,927,796]	-7	hSpCas9	negative selection	6097575
53432240	53432263	X	+	27260156	CAL120	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.17911391854076686	[725]	[864,930,610]	-3	hSpCas9	negative selection	6097576
53432017	53432040	X	+	27260156	CAL120	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.7823031191279064	[1345]	[435,476,538]	-9	hSpCas9	negative selection	6097577
53433820	53433843	X	-	27260156	CADOES1	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.004574328459053312	[412]	[319,254,431,529]	0	hSpCas9	negative selection	6154566
53433818	53433841	X	+	27260156	CADOES1	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.0562396756851358	[634]	[204,261,286,385]	-9	hSpCas9	negative selection	6154567
53432080	53432103	X	-	27260156	CADOES1	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.0439006173839287	[597]	[623,628,452,587]	0	hSpCas9	negative selection	6154568
53431859	53431882	X	+	27260156	CADOES1	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.3532309926477627	[1196]	[661,834,1026,965]	-6	hSpCas9	negative selection	6218826
53432240	53432263	X	+	27260156	CADOES1	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.6502991132629543	[725]	[562,495,325,331]	-8	hSpCas9	negative selection	6218827
53432017	53432040	X	+	27260156	CADOES1	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.6539076427546758	[1345]	[630,604,932,1021]	-8	hSpCas9	negative selection	6218828
53433820	53433843	X	-	27260156	EWS502	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.2201464248302964	[412]	[116,174,324,140]	-9	hSpCas9	negative selection	6275817
53433818	53433841	X	+	27260156	EWS502	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-2.0073573411702768	[634]	[227,115,167,149]	-9	hSpCas9	negative selection	6275818
53432080	53432103	X	-	27260156	EWS502	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.12149772859393632	[597]	[669,617,814,654]	2	hSpCas9	negative selection	6275819
53431859	53431882	X	+	27260156	EWS502	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.38235327712437495	[1196]	[726,1017,1328,835]	-6	hSpCas9	negative selection	6340077
53432240	53432263	X	+	27260156	EWS502	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.9132938559561568	[725]	[424,324,441,443]	-8	hSpCas9	negative selection	6340078
53432017	53432040	X	+	27260156	EWS502	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.0751906216518057	[1345]	[488,816,767,645]	-9	hSpCas9	negative selection	6340079
53433820	53433843	X	-	27260156	EW8	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.5065442786564137	[412]	[408,142,142,280]	-7	hSpCas9	negative selection	6397068
53433818	53433841	X	+	27260156	EW8	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.559671580315062	[634]	[203,127,154,216]	-9	hSpCas9	negative selection	6397069
53432080	53432103	X	-	27260156	EW8	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.14056907263047191	[597]	[500,487,394,387]	-3	hSpCas9	negative selection	6397070
53431859	53431882	X	+	27260156	EW8	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.6647816436711811	[1196]	[680,597,596,579]	-8	hSpCas9	negative selection	6461328
53432240	53432263	X	+	27260156	EW8	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.8393963547429135	[725]	[390,524,243,176]	-9	hSpCas9	negative selection	6461329
53432017	53432040	X	+	27260156	EW8	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.9351694024839938	[1345]	[515,612,464,697]	-9	hSpCas9	negative selection	6461330
53433820	53433843	X	-	27260156	CORL105	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.594096164251964	[412]	[360,323,297,295]	-8	hSpCas9	negative selection	6518319
53433818	53433841	X	+	27260156	CORL105	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.0973380597496867	[634]	[398,320,315,350]	-9	hSpCas9	negative selection	6518320
53432080	53432103	X	-	27260156	CORL105	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.06563397215038619	[597]	[609,577,864,652]	-1	hSpCas9	negative selection	6518321
53431859	53431882	X	+	27260156	CORL105	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.3586682952360054	[1196]	[948,1123,1098,1193]	-6	hSpCas9	negative selection	6582579
53432240	53432263	X	+	27260156	CORL105	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.0328031193269487	[725]	[359,419,444,438]	-9	hSpCas9	negative selection	6582580
53432017	53432040	X	+	27260156	CORL105	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.9861200522576863	[1345]	[927,639,706,899]	-9	hSpCas9	negative selection	6582581
53433820	53433843	X	-	27260156	HS294T	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.808866378146704	[412]	[53,102,96,117]	-8	hSpCas9	negative selection	6639570
53433818	53433841	X	+	27260156	HS294T	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.2208373450567074	[634]	[49,61,119,213]	-9	hSpCas9	negative selection	6639571
53432080	53432103	X	-	27260156	HS294T	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.2886176412314495	[597]	[337,255,218,316]	4	hSpCas9	negative selection	6639572
53431859	53431882	X	+	27260156	HS294T	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.2961969345488582	[1196]	[339,338,396,446]	-4	hSpCas9	negative selection	6703830
53432240	53432263	X	+	27260156	HS294T	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.3677320850161765	[725]	[240,103,193,354]	-5	hSpCas9	negative selection	6703831
53432017	53432040	X	+	27260156	HS294T	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.8500226144909039	[1345]	[250,292,286,333]	-8	hSpCas9	negative selection	6703832
53433820	53433843	X	-	27260156	HCC44	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.5504738106260612	[412]	[113,223,127,151]	-9	hSpCas9	negative selection	6760821
53433818	53433841	X	+	27260156	HCC44	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-2.003367256683328	[634]	[199,153,217,155]	-9	hSpCas9	negative selection	6760822
53432080	53432103	X	-	27260156	HCC44	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.1464988150978422	[597]	[640,532,735,565]	-2	hSpCas9	negative selection	6760823
53431859	53431882	X	+	27260156	HCC44	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.4213203487225454	[1196]	[870,1156,1179,828]	-6	hSpCas9	negative selection	6825081
53432240	53432263	X	+	27260156	HCC44	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.8484371866067967	[725]	[487,504,359,446]	-8	hSpCas9	negative selection	6825082
53432017	53432040	X	+	27260156	HCC44	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.4278442193707432	[1345]	[796,490,632,386]	-9	hSpCas9	negative selection	6825083
53433820	53433843	X	-	27260156	G402	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.2174322604143835	[412]	[239,166,337,125]	-8	hSpCas9	negative selection	6882072
53433818	53433841	X	+	27260156	G402	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.4348844318977503	[634]	[410,280,334,142]	-9	hSpCas9	negative selection	6882073
53432080	53432103	X	-	27260156	G402	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.32240498840171655	[597]	[857,679,590,263]	-4	hSpCas9	negative selection	6882074
53431859	53431882	X	+	27260156	G402	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.8956373786632559	[1196]	[755,968,956,476]	-8	hSpCas9	negative selection	6946332
53432240	53432263	X	+	27260156	G402	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.4240176504282122	[725]	[663,758,734,494]	-5	hSpCas9	negative selection	6946333
53432017	53432040	X	+	27260156	G402	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.5419539719082165	[1345]	[574,544,582,551]	-9	hSpCas9	negative selection	6946334
53433820	53433843	X	-	27260156	L33	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.6694839850604654	[412]	[253,79,177,305]	-9	hSpCas9	negative selection	7003323
53433818	53433841	X	+	27260156	L33	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.1153426257746257	[634]	[296,122,175,294]	-9	hSpCas9	negative selection	7003324
53432080	53432103	X	-	27260156	L33	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.3367141714176026	[597]	[736,292,442,862]	7	hSpCas9	negative selection	7003325
53431859	53431882	X	+	27260156	L33	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	0.3027090061106079	[1196]	[1488,518,954,1628]	6	hSpCas9	negative selection	7067583
53432240	53432263	X	+	27260156	L33	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.56058670675625	[725]	[353,229,406,410]	-8	hSpCas9	negative selection	7067584
53432017	53432040	X	+	27260156	L33	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.5284789651252315	[1345]	[959,418,571,839]	-8	hSpCas9	negative selection	7067585
53433820	53433843	X	-	27260156	K562	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.4400867646325106	[412]	[272,35,178,65]	-9	hSpCas9	negative selection	7124574
53433818	53433841	X	+	27260156	K562	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-3.155610671950065	[634]	[95,61,68,31]	-9	hSpCas9	negative selection	7124575
53432080	53432103	X	-	27260156	K562	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.05987734705125297	[597]	[540,710,368,591]	0	hSpCas9	negative selection	7124576
53431859	53431882	X	+	27260156	K562	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.2749833025881392	[1196]	[953,831,878,849]	-3	hSpCas9	negative selection	7188834
53432240	53432263	X	+	27260156	K562	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.2799723132696998	[725]	[450,391,171,87]	-8	hSpCas9	negative selection	7188835
53432017	53432040	X	+	27260156	K562	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.7893857194822087	[1345]	[310,279,423,357]	-9	hSpCas9	negative selection	7188836
53433820	53433843	X	-	27260156	HT29	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.2888980056387127	[412]	[199,226,217,179]	-9	hSpCas9	negative selection	7245825
53433818	53433841	X	+	27260156	HT29	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.9129702214382072	[634]	[197,124,246,236]	-9	hSpCas9	negative selection	7245826
53432080	53432103	X	-	27260156	HT29	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.02480848230433358	[597]	[880,826,583,597]	0	hSpCas9	negative selection	7245827
53431859	53431882	X	+	27260156	HT29	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.6745494335723564	[1196]	[1031,949,906,779]	-8	hSpCas9	negative selection	7310085
53432240	53432263	X	+	27260156	HT29	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.6847402559186206	[725]	[455,569,487,658]	-8	hSpCas9	negative selection	7310086
53432017	53432040	X	+	27260156	HT29	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.3540627688531135	[1345]	[718,579,585,667]	-9	hSpCas9	negative selection	7310087
53433820	53433843	X	-	27260156	MHHES1	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.5495963987811465	[412]	[341,408,336,212]	-8	hSpCas9	negative selection	7367076
53433818	53433841	X	+	27260156	MHHES1	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.6626894253669395	[634]	[668,456,380,341]	-8	hSpCas9	negative selection	7367077
53432080	53432103	X	-	27260156	MHHES1	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.11170410974972772	[597]	[821,896,712,535]	2	hSpCas9	negative selection	7367078
53431859	53431882	X	+	27260156	MHHES1	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.5833038615445253	[1196]	[894,1145,872,728]	-8	hSpCas9	negative selection	7431336
53432240	53432263	X	+	27260156	MHHES1	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.0332840456697663	[725]	[261,376,280,600]	-9	hSpCas9	negative selection	7431337
53432017	53432040	X	+	27260156	MHHES1	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.7404344211689405	[1345]	[746,1348,785,780]	-8	hSpCas9	negative selection	7431338
53433820	53433843	X	-	27260156	MEWO	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.23793418451522025	[412]	[400,339,255]	-5	hSpCas9	negative selection	7488327
53433818	53433841	X	+	27260156	MEWO	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.5075670706067538	[634]	[557,355,366]	-8	hSpCas9	negative selection	7488328
53432080	53432103	X	-	27260156	MEWO	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.32125599013395123	[597]	[853,676,595]	7	hSpCas9	negative selection	7488329
53431859	53431882	X	+	27260156	MEWO	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.023315556505794754	[1196]	[1124,1095,1088]	0	hSpCas9	negative selection	7552587
53432240	53432263	X	+	27260156	MEWO	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.8037587288314476	[725]	[490,375,319]	-9	hSpCas9	negative selection	7552588
53432017	53432040	X	+	27260156	MEWO	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.6322373489024393	[1345]	[926,884,646]	-8	hSpCas9	negative selection	7552589
53433820	53433843	X	-	27260156	LNCAPCLONEFGC	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.0425739659971227	[412]	[260,151,135,170]	-9	hSpCas9	negative selection	7609578
53433818	53433841	X	+	27260156	LNCAPCLONEFGC	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.5085763291011094	[634]	[178,235,176,210]	-9	hSpCas9	negative selection	7609579
53432080	53432103	X	-	27260156	LNCAPCLONEFGC	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.09111458149598456	[597]	[593,373,507,564]	-1	hSpCas9	negative selection	7609580
53431859	53431882	X	+	27260156	LNCAPCLONEFGC	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.9392875984244871	[1196]	[539,552,620,556]	-8	hSpCas9	negative selection	7673838
53432240	53432263	X	+	27260156	LNCAPCLONEFGC	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.5212880688354057	[725]	[348,402,583,520]	-7	hSpCas9	negative selection	7673839
53432017	53432040	X	+	27260156	LNCAPCLONEFGC	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.388242814802599	[1345]	[392,582,515,371]	-9	hSpCas9	negative selection	7673840
53433820	53433843	X	-	27260156	PANC0327	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.5508373278393063	[412]	[265,163,231,351]	-7	hSpCas9	negative selection	7730829
53433818	53433841	X	+	27260156	PANC0327	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.1164557955576864	[634]	[187,210,287,353]	-8	hSpCas9	negative selection	7730830
53432080	53432103	X	-	27260156	PANC0327	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.3660215561272112	[597]	[611,681,852,585]	5	hSpCas9	negative selection	7730831
53431859	53431882	X	+	27260156	PANC0327	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.13352919957310627	[1196]	[1047,1024,846,955]	-2	hSpCas9	negative selection	7795089
53432240	53432263	X	+	27260156	PANC0327	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.49215100676130497	[725]	[703,285,323,561]	-6	hSpCas9	negative selection	7795090
53432017	53432040	X	+	27260156	PANC0327	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.9298656486363047	[1345]	[661,458,737,675]	-8	hSpCas9	negative selection	7795091
53433820	53433843	X	-	27260156	NCIH2009	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.7765350170420668	[412]	[199,180,129]	-9	hSpCas9	negative selection	7852080
53433818	53433841	X	+	27260156	NCIH2009	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.456649337509428	[634]	[390,243,348]	-9	hSpCas9	negative selection	7852081
53432080	53432103	X	-	27260156	NCIH2009	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.004926609037209317	[597]	[1271,637,692]	0	hSpCas9	negative selection	7852082
53431859	53431882	X	+	27260156	NCIH2009	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-1.0957734752053312	[1196]	[1050,628,721]	-8	hSpCas9	negative selection	7916340
53432240	53432263	X	+	27260156	NCIH2009	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.1898388520955834	[725]	[468,497,369]	-8	hSpCas9	negative selection	7916341
53432017	53432040	X	+	27260156	NCIH2009	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.5044264150985964	[1345]	[973,547,528]	-9	hSpCas9	negative selection	7916342
53433820	53433843	X	-	27260156	NCIH1373	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.0243413135072816	[412]	[162,205,305,58]	-8	hSpCas9	negative selection	7973331
53433818	53433841	X	+	27260156	NCIH1373	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.7134353134460172	[634]	[209,133,346,46]	-9	hSpCas9	negative selection	7973332
53432080	53432103	X	-	27260156	NCIH1373	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.03470398544427428	[597]	[708,443,721,203]	0	hSpCas9	negative selection	7973333
53431859	53431882	X	+	27260156	NCIH1373	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.452355247509598	[1196]	[1069,914,813,302]	-4	hSpCas9	negative selection	8037591
53432240	53432263	X	+	27260156	NCIH1373	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.8491460614965975	[725]	[284,442,605,115]	-7	hSpCas9	negative selection	8037592
53432017	53432040	X	+	27260156	NCIH1373	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.9610518903822873	[1345]	[919,789,447,256]	-7	hSpCas9	negative selection	8037593
53433820	53433843	X	-	27260156	PATU8902	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-1.041919417025745	[412]	[265,285,283,277]	-7	hSpCas9	negative selection	8094582
53433818	53433841	X	+	27260156	PATU8902	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.7125162008587593	[634]	[313,277,195,312]	-8	hSpCas9	negative selection	8094583
53432080	53432103	X	-	27260156	PATU8902	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.23342358995252274	[597]	[685,532,751,863]	-2	hSpCas9	negative selection	8094584
53431859	53431882	X	+	27260156	PATU8902	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.8857671460821402	[1196]	[1040,1064,753,761]	-7	hSpCas9	negative selection	8158842
53432240	53432263	X	+	27260156	PATU8902	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.5023501366432919	[725]	[834,573,884,480]	-5	hSpCas9	negative selection	8158843
53432017	53432040	X	+	27260156	PATU8902	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.153647180267032	[1345]	[823,973,916,600]	-7	hSpCas9	negative selection	8158844
53433820	53433843	X	-	27260156	PANC1	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.5922185833795512	[412]	[197,247,352,155]	-7	hSpCas9	negative selection	8215833
53433818	53433841	X	+	27260156	PANC1	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.401646145999859	[634]	[191,259,152,224]	-9	hSpCas9	negative selection	8215834
53432080	53432103	X	-	27260156	PANC1	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.07371402850671893	[597]	[431,763,372,439]	-1	hSpCas9	negative selection	8215835
53431859	53431882	X	+	27260156	PANC1	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.37576618739590706	[1196]	[786,924,892,609]	-5	hSpCas9	negative selection	8280093
53432240	53432263	X	+	27260156	PANC1	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.7183395483157852	[725]	[286,416,410,400]	-7	hSpCas9	negative selection	8280094
53432017	53432040	X	+	27260156	PANC1	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-1.2780256742870806	[1345]	[483,724,460,307]	-9	hSpCas9	negative selection	8280095
53433820	53433843	X	-	27260156	PANC0813	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.18830796379070341	[412]	[356,400,573,367]	-3	hSpCas9	negative selection	8337084
53433818	53433841	X	+	27260156	PANC0813	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.43619301515157394	[634]	[473,685,559,480]	-6	hSpCas9	negative selection	8337085
53432080	53432103	X	-	27260156	PANC0813	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.04071107639935001	[597]	[888,501,545,804]	0	hSpCas9	negative selection	8337086
53431859	53431882	X	+	27260156	PANC0813	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.17039078840421107	[1196]	[1268,1246,1260,1221]	-3	hSpCas9	negative selection	8401344
53432240	53432263	X	+	27260156	PANC0813	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.2710508384026533	[725]	[404,299,398,315]	-9	hSpCas9	negative selection	8401345
53432017	53432040	X	+	27260156	PANC0813	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.5029342593150312	[1345]	[1117,1100,1001,1232]	-6	hSpCas9	negative selection	8401346
53433820	53433843	X	-	27260156	RDES	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.18048858146877006	[412]	[281,446,514,456]	-3	hSpCas9	negative selection	8458335
53433818	53433841	X	+	27260156	RDES	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.1580910264306311	[634]	[576,671,612,764]	-3	hSpCas9	negative selection	8458336
53432080	53432103	X	-	27260156	RDES	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.30228363624997123	[597]	[769,729,956,956]	5	hSpCas9	negative selection	8458337
53431859	53431882	X	+	27260156	RDES	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	0.093480747945065	[1196]	[1198,1535,1472,1709]	1	hSpCas9	negative selection	8522595
53432240	53432263	X	+	27260156	RDES	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.4821127878705985	[725]	[612,494,621,656]	-7	hSpCas9	negative selection	8522596
53432017	53432040	X	+	27260156	RDES	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.5492819206462835	[1345]	[898,1139,1115,1072]	-7	hSpCas9	negative selection	8522597
53433820	53433843	X	-	27260156	PC3	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.07380114256292053	[412]	[289,342,558,442]	-2	hSpCas9	negative selection	8579586
53433818	53433841	X	+	27260156	PC3	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.3625263496502555	[634]	[305,493,680,599]	-7	hSpCas9	negative selection	8579587
53432080	53432103	X	-	27260156	PC3	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.16699386467902633	[597]	[559,673,887,598]	4	hSpCas9	negative selection	8579588
53431859	53431882	X	+	27260156	PC3	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	0.06698910013986192	[1196]	[833,1096,2138,1342]	1	hSpCas9	negative selection	8643846
53432240	53432263	X	+	27260156	PC3	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.3967763300501497	[725]	[328,536,1215,416]	-7	hSpCas9	negative selection	8643847
53432017	53432040	X	+	27260156	PC3	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.38291041927917613	[1345]	[745,1104,1682,831]	-7	hSpCas9	negative selection	8643848
53433820	53433843	X	-	27260156	PATU8988T	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.5504892361167512	[412]	[212,360,324,191]	-7	hSpCas9	negative selection	8700837
53433818	53433841	X	+	27260156	PATU8988T	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.109844658443061	[634]	[240,328,426,129]	-9	hSpCas9	negative selection	8700838
53432080	53432103	X	-	27260156	PATU8988T	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.4061834559759239	[597]	[226,444,557,519]	-6	hSpCas9	negative selection	8700839
53431859	53431882	X	+	27260156	PATU8988T	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.4807105730618809	[1196]	[400,1055,1082,789]	-7	hSpCas9	negative selection	8765097
53432240	53432263	X	+	27260156	PATU8988T	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.2078996210695676	[725]	[369,228,223,392]	-9	hSpCas9	negative selection	8765098
53432017	53432040	X	+	27260156	PATU8988T	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.8788672491365487	[1345]	[485,800,517,1063]	-8	hSpCas9	negative selection	8765099
53433820	53433843	X	-	27260156	T47D	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.674275512872539	[412]	[343,282,239,342]	-8	hSpCas9	negative selection	8822088
53433818	53433841	X	+	27260156	T47D	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.0357056128684103	[634]	[436,374,285,344]	-9	hSpCas9	negative selection	8822089
53432080	53432103	X	-	27260156	T47D	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.023558063208705182	[597]	[839,564,689,751]	0	hSpCas9	negative selection	8822090
53431859	53431882	X	+	27260156	T47D	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.11693868596893453	[1196]	[1180,1282,1337,1341]	-3	hSpCas9	negative selection	8886348
53432240	53432263	X	+	27260156	T47D	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.3784575248509744	[725]	[615,538,690,768]	-7	hSpCas9	negative selection	8886349
53432017	53432040	X	+	27260156	T47D	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.8435307924279142	[1345]	[1008,712,792,999]	-9	hSpCas9	negative selection	8886350
53433820	53433843	X	-	27260156	SU8686	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.49204104825871164	[412]	[276,356,281,228]	-7	hSpCas9	negative selection	8943339
53433818	53433841	X	+	27260156	SU8686	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.882363539952679	[634]	[410,282,325,342]	-8	hSpCas9	negative selection	8943340
53432080	53432103	X	-	27260156	SU8686	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.10875716240402439	[597]	[504,463,600,660]	-2	hSpCas9	negative selection	8943341
53431859	53431882	X	+	27260156	SU8686	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.27958526119591354	[1196]	[923,1032,997,941]	-5	hSpCas9	negative selection	9007599
53432240	53432263	X	+	27260156	SU8686	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.9785334046968783	[725]	[287,387,361,437]	-8	hSpCas9	negative selection	9007600
53432017	53432040	X	+	27260156	SU8686	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.9322794184199943	[1345]	[785,621,644,744]	-8	hSpCas9	negative selection	9007601
53433820	53433843	X	-	27260156	SKES1	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.335077246248091	[412]	[267,423,381,241]	-6	hSpCas9	negative selection	9064590
53433818	53433841	X	+	27260156	SKES1	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.7442098948688137	[634]	[318,502,323,370]	-9	hSpCas9	negative selection	9064591
53432080	53432103	X	-	27260156	SKES1	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.24365945110044696	[597]	[819,515,739,730]	5	hSpCas9	negative selection	9064592
53431859	53431882	X	+	27260156	SKES1	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	0.0946905145362531	[1196]	[1431,1543,1249,953]	2	hSpCas9	negative selection	9128850
53432240	53432263	X	+	27260156	SKES1	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.7878639411612657	[725]	[462,439,269,500]	-9	hSpCas9	negative selection	9128851
53432017	53432040	X	+	27260156	SKES1	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.474673248677399	[1345]	[1215,1174,709,832]	-8	hSpCas9	negative selection	9128852
53433820	53433843	X	-	27260156	TOV112D	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.013205756284923209	[412]	[354,642,480,217]	0	hSpCas9	negative selection	9185841
53433818	53433841	X	+	27260156	TOV112D	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-1.3459331499449716	[634]	[146,301,325,229]	-9	hSpCas9	negative selection	9185842
53432080	53432103	X	-	27260156	TOV112D	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.04868637497636602	[597]	[453,890,620,419]	-1	hSpCas9	negative selection	9185843
53431859	53431882	X	+	27260156	TOV112D	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.27039898370044346	[1196]	[831,1342,969,903]	-5	hSpCas9	negative selection	9250101
53432240	53432263	X	+	27260156	TOV112D	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-1.0224460948120258	[725]	[299,502,408,252]	-9	hSpCas9	negative selection	9250102
53432017	53432040	X	+	27260156	TOV112D	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.7913972975879099	[1345]	[629,888,472,1126]	-9	hSpCas9	negative selection	9250103
53433820	53433843	X	-	27260156	TC71	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.24877973512327706	[412]	[291,449,386,361]	-6	hSpCas9	negative selection	9307092
53433818	53433841	X	+	27260156	TC71	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.6167929324760597	[634]	[468,397,366,549]	-9	hSpCas9	negative selection	9307093
53432080	53432103	X	-	27260156	TC71	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	0.08981832398413803	[597]	[628,756,667,675]	2	hSpCas9	negative selection	9307094
53431859	53431882	X	+	27260156	TC71	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.07849583225004908	[1196]	[1238,1101,1133,1398]	-2	hSpCas9	negative selection	9371352
53432240	53432263	X	+	27260156	TC71	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.41081961675854833	[725]	[671,531,517,621]	-8	hSpCas9	negative selection	9371353
53432017	53432040	X	+	27260156	TC71	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.6148360159307676	[1345]	[1022,894,767,1095]	-9	hSpCas9	negative selection	9371354
53433820	53433843	X	-	27260156	TC32	viability	GGCCACGGCGGAGCGACTTGTGG	HSD17B10	ENSG00000072506	-0.19910495540488943	[412]	[345,140,451,497]	-4	hSpCas9	negative selection	9428343
53433818	53433841	X	+	27260156	TC32	viability	CCCCACAAGTCGCTCCGCCGTGG	HSD17B10	ENSG00000072506	-0.47958850622621507	[634]	[386,380,460,487]	-7	hSpCas9	negative selection	9428344
53432080	53432103	X	-	27260156	TC32	viability	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.0033588375778940693	[597]	[707,280,757,585]	0	hSpCas9	negative selection	9428345
53431859	53431882	X	+	27260156	TC32	viability	CATGCCCACTATTCCCCCCTTGG	HSD17B10	ENSG00000072506	-0.2715729066031405	[1196]	[856,699,1108,1145]	-5	hSpCas9	negative selection	9492603
53432240	53432263	X	+	27260156	TC32	viability	GCCTTACATCAAGAACTCGCTGG	HSD17B10	ENSG00000072506	-0.21317720296916415	[725]	[576,582,577,577]	-4	hSpCas9	negative selection	9492604
53432017	53432040	X	+	27260156	TC32	viability	TGTTGATGATGACCCCACGTTGG	HSD17B10	ENSG00000072506	-0.45525272067098665	[1345]	[835,946,971,881]	-7	hSpCas9	negative selection	9492605
53431401	53431424	X	+	27869803	HPAFII	viability after 27 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	2.719110409271625	[24]	[169,16,NaN]	9	hSpCas9	negative selection	9609150
53431508	53431531	X	-	27869803	HPAFII	viability after 27 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.4034079445000667	[93]	[114,23,NaN]	3	hSpCas9	negative selection	9609151
53431872	53431895	X	-	27869803	HPAFII	viability after 27 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-2.4043614291396778	[367]	[47,26,NaN]	-8	hSpCas9	negative selection	9609152
53432080	53432103	X	-	27869803	HPAFII	viability after 27 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-3.0593633927988497	[159]	[20,0,NaN]	-9	hSpCas9	negative selection	9609153
53432315	53432338	X	-	27869803	HPAFII	viability after 27 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.4901409123767566	[374]	[10,22,NaN]	-9	hSpCas9	negative selection	9609154
53433862	53433885	X	+	27869803	HPAFII	viability after 27 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.32829117215544545	[206]	[152,122,NaN]	2	hSpCas9	negative selection	9609155
53431401	53431424	X	+	27869803	HPAFII	viability after 15 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	3.402194847552717	[24]	[333,252,NaN]	9	hSpCas9	negative selection	9691599
53431508	53431531	X	-	27869803	HPAFII	viability after 15 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.6504350890563593	[93]	[218,120,NaN]	7	hSpCas9	negative selection	9691600
53431872	53431895	X	-	27869803	HPAFII	viability after 15 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-0.5507772867871698	[367]	[507,121,NaN]	-5	hSpCas9	negative selection	9691601
53432080	53432103	X	-	27869803	HPAFII	viability after 15 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-0.015911818621178297	[159]	[211,143,NaN]	0	hSpCas9	negative selection	9691602
53432315	53432338	X	-	27869803	HPAFII	viability after 15 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.7105496741952972	[374]	[206,70,NaN]	-9	hSpCas9	negative selection	9691603
53433862	53433885	X	+	27869803	HPAFII	viability after 15 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.20451879508006396	[206]	[272,245,NaN]	2	hSpCas9	negative selection	9691604
53431401	53431424	X	+	27869803	ASPC1	viability after 36 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.2984481822156265	[612]	[131,468,188]	3	hSpCas9	negative selection	9774048
53431508	53431531	X	-	27869803	ASPC1	viability after 36 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.6548842358935747	[286]	[128,249,102]	6	hSpCas9	negative selection	9774049
53431872	53431895	X	-	27869803	ASPC1	viability after 36 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-1.3687907826028036	[1092]	[138,195,113]	-8	hSpCas9	negative selection	9774050
53432080	53432103	X	-	27869803	ASPC1	viability after 36 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-1.0133175447244946	[440]	[137,49,52]	-7	hSpCas9	negative selection	9774051
53432315	53432338	X	-	27869803	ASPC1	viability after 36 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.8587314950177378	[964]	[185,80,35]	-9	hSpCas9	negative selection	9774052
53433862	53433885	X	+	27869803	ASPC1	viability after 36 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.09911925745609129	[460]	[170,235,120]	1	hSpCas9	negative selection	9774053
53431401	53431424	X	+	27869803	PATU8988S	viability after 35 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.18561726848962626	[621]	[243,325,NaN]	2	hSpCas9	negative selection	9856497
53431508	53431531	X	-	27869803	PATU8988S	viability after 35 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-1.3194105584216205	[253]	[36,44,NaN]	-8	hSpCas9	negative selection	9856498
53431872	53431895	X	-	27869803	PATU8988S	viability after 35 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-2.658741962883953	[823]	[75,28,NaN]	-9	hSpCas9	negative selection	9856499
53432080	53432103	X	-	27869803	PATU8988S	viability after 35 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-2.066717346530536	[327]	[45,16,NaN]	-9	hSpCas9	negative selection	9856500
53432315	53432338	X	-	27869803	PATU8988S	viability after 35 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.714025347334925	[798]	[67,29,NaN]	-9	hSpCas9	negative selection	9856501
53433862	53433885	X	+	27869803	PATU8988S	viability after 35 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-1.1904164603345155	[532]	[120,66,NaN]	-8	hSpCas9	negative selection	9856502
53431401	53431424	X	+	27869803	PATU8988S	viability after 31 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	0.3884917300717061	[621]	[237,434,NaN]	5	hSpCas9	negative selection	9938946
53431508	53431531	X	-	27869803	PATU8988S	viability after 31 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.23606686434285362	[253]	[52,127,NaN]	-3	hSpCas9	negative selection	9938947
53431872	53431895	X	-	27869803	PATU8988S	viability after 31 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-2.5401728650246995	[823]	[92,9,NaN]	-9	hSpCas9	negative selection	9938948
53432080	53432103	X	-	27869803	PATU8988S	viability after 31 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-2.686436641780634	[327]	[7,35,NaN]	-9	hSpCas9	negative selection	9938949
53432315	53432338	X	-	27869803	PATU8988S	viability after 31 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.073523012785532	[798]	[65,1,NaN]	-9	hSpCas9	negative selection	9938950
53433862	53433885	X	+	27869803	PATU8988S	viability after 31 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	-0.8328631663115345	[532]	[106,134,NaN]	-7	hSpCas9	negative selection	9938951
53431401	53431424	X	+	27869803	HPAFII	viability after 35 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	2.9413162231383305	[24]	[171,12,NaN]	9	hSpCas9	negative selection	10021395
53431508	53431531	X	-	27869803	HPAFII	viability after 35 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	-0.4847020639522115	[93]	[49,15,NaN]	-3	hSpCas9	negative selection	10021396
53431872	53431895	X	-	27869803	HPAFII	viability after 35 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-3.3996994419321744	[367]	[27,5,NaN]	-8	hSpCas9	negative selection	10021397
53432080	53432103	X	-	27869803	HPAFII	viability after 35 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-3.460970776525846	[159]	[12,0,NaN]	-8	hSpCas9	negative selection	10021398
53432315	53432338	X	-	27869803	HPAFII	viability after 35 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.65078499910013	[374]	[8,21,NaN]	-9	hSpCas9	negative selection	10021399
53433862	53433885	X	+	27869803	HPAFII	viability after 35 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	1.0577011451299452	[206]	[140,304,NaN]	7	hSpCas9	negative selection	10021400
53431401	53431424	X	+	27869803	HPAFII	viability after 31 days	CCTTCAAGGCTGCATACGAATGG	HSD17B10	ENSG00000072506	3.8069562369813976	[24]	[226,162,NaN]	9	hSpCas9	negative selection	10103844
53431508	53431531	X	-	27869803	HPAFII	viability after 31 days	AGTGCCCTTCCCTAGCCGACTGG	HSD17B10	ENSG00000072506	0.4455551691314382	[93]	[112,26,NaN]	3	hSpCas9	negative selection	10103845
53431872	53431895	X	-	27869803	HPAFII	viability after 31 days	GCATACTCTGCTTCCAAGGGGGG	HSD17B10	ENSG00000072506	-3.1160027272547746	[367]	[30,15,NaN]	-9	hSpCas9	negative selection	10103846
53432080	53432103	X	-	27869803	HPAFII	viability after 31 days	CACCTTCAATGTGATCCGCCTGG	HSD17B10	ENSG00000072506	-2.4466631145052995	[159]	[26,4,NaN]	-8	hSpCas9	negative selection	10103847
53432315	53432338	X	-	27869803	HPAFII	viability after 31 days	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.452195908042635	[374]	[1,37,NaN]	-9	hSpCas9	negative selection	10103848
53433862	53433885	X	+	27869803	HPAFII	viability after 31 days	CTCCGGTTATTACCGCCACCAGG	HSD17B10	ENSG00000072506	0.2808965517030058	[206]	[121,161,NaN]	2	hSpCas9	negative selection	10103849
53433861	53433884	X	-	28162770	P31FUJ	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-3.9800361340344117	[281]	[20]	-9	hSpCas9	negative selection	10171394
53433710	53433733	X	+	28162770	P31FUJ	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.564645768166824	[145]	[28]	-8	hSpCas9	negative selection	10171395
53433788	53433811	X	+	28162770	P31FUJ	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-4.132275328460414	[387]	[25]	-9	hSpCas9	negative selection	10171396
53432378	53432401	X	-	28162770	P31FUJ	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-4.574270485697386	[222]	[10]	-9	hSpCas9	negative selection	10171397
53432315	53432338	X	-	28162770	P31FUJ	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.8106752803492157	[202]	[16]	-9	hSpCas9	negative selection	10171398
53432043	53432066	X	-	28162770	P31FUJ	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-4.185135770784065	[386]	[24]	-9	hSpCas9	negative selection	10171399
53433774	53433797	X	-	28162770	P31FUJ	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.6566099133209546	[109]	[81]	-5	hSpCas9	negative selection	10171400
53432270	53432293	X	-	28162770	P31FUJ	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.7388638773886197	[506]	[356]	-5	hSpCas9	negative selection	10171401
53432065	53432088	X	+	28162770	P31FUJ	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.4789627916837762	[203]	[85]	-7	hSpCas9	negative selection	10171402
53431829	53431852	X	+	28162770	P31FUJ	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-2.2924451508417807	[320]	[76]	-8	hSpCas9	negative selection	10171403
53433861	53433884	X	-	28162770	TF1	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10340760
53433710	53433733	X	+	28162770	TF1	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10340761
53433788	53433811	X	+	28162770	TF1	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10340762
53432378	53432401	X	-	28162770	TF1	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10340763
53432315	53432338	X	-	28162770	TF1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10340764
53432043	53432066	X	-	28162770	TF1	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10340765
53433774	53433797	X	-	28162770	TF1	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10340766
53432270	53432293	X	-	28162770	TF1	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10340767
53432065	53432088	X	+	28162770	TF1	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10340768
53431829	53431852	X	+	28162770	TF1	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10340769
53433861	53433884	X	-	28162770	SKM1	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-7.2143191208007655	[83]	[0]	-9	hSpCas9	negative selection	10510126
53433710	53433733	X	+	28162770	SKM1	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-4.822001698022005	[31]	[1]	-9	hSpCas9	negative selection	10510127
53433788	53433811	X	+	28162770	SKM1	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-4.617860981241781	[124]	[8]	-9	hSpCas9	negative selection	10510128
53432378	53432401	X	-	28162770	SKM1	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.5038257379957507	[76]	[23]	-9	hSpCas9	negative selection	10510129
53432315	53432338	X	-	28162770	SKM1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.620367836852355	[39]	[22]	-8	hSpCas9	negative selection	10510130
53432043	53432066	X	-	28162770	SKM1	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.951284714966972	[104]	[23]	-9	hSpCas9	negative selection	10510131
53433774	53433797	X	-	28162770	SKM1	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	0.2175266661646318	[17]	[36]	2	hSpCas9	negative selection	10510132
53432270	53432293	X	-	28162770	SKM1	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.6479722982469569	[116]	[131]	-5	hSpCas9	negative selection	10510133
53432065	53432088	X	+	28162770	SKM1	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.46585788779673	[49]	[15]	-9	hSpCas9	negative selection	10510134
53431829	53431852	X	+	28162770	SKM1	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.9243634156516833	[72]	[33]	-8	hSpCas9	negative selection	10510135
53433861	53433884	X	-	28162770	SKM1	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-7.2143191208007655	[83]	[0]	-9	hSpCas9	negative selection	10679492
53433710	53433733	X	+	28162770	SKM1	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-4.822001698022005	[31]	[1]	-9	hSpCas9	negative selection	10679493
53433788	53433811	X	+	28162770	SKM1	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-4.617860981241781	[124]	[8]	-9	hSpCas9	negative selection	10679494
53432378	53432401	X	-	28162770	SKM1	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.5038257379957507	[76]	[23]	-9	hSpCas9	negative selection	10679495
53432315	53432338	X	-	28162770	SKM1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-1.620367836852355	[39]	[22]	-8	hSpCas9	negative selection	10679496
53432043	53432066	X	-	28162770	SKM1	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.951284714966972	[104]	[23]	-9	hSpCas9	negative selection	10679497
53433774	53433797	X	-	28162770	SKM1	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	0.2175266661646318	[17]	[36]	2	hSpCas9	negative selection	10679498
53432270	53432293	X	-	28162770	SKM1	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.6479722982469569	[116]	[131]	-5	hSpCas9	negative selection	10679499
53432065	53432088	X	+	28162770	SKM1	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.46585788779673	[49]	[15]	-9	hSpCas9	negative selection	10679500
53431829	53431852	X	+	28162770	SKM1	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.9243634156516833	[72]	[33]	-8	hSpCas9	negative selection	10679501
53433861	53433884	X	-	28162770	PL21	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-2.805859126132123	[240]	[14]	-9	hSpCas9	negative selection	10848858
53433710	53433733	X	+	28162770	PL21	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.9896849443906977	[72]	[3]	-9	hSpCas9	negative selection	10848859
53433788	53433811	X	+	28162770	PL21	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-2.7842297337969155	[458]	[28]	-9	hSpCas9	negative selection	10848860
53432378	53432401	X	-	28162770	PL21	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-0.03523844844160833	[185]	[78]	0	hSpCas9	negative selection	10848861
53432315	53432338	X	-	28162770	PL21	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.462825398233109	[151]	[11]	-9	hSpCas9	negative selection	10848862
53432043	53432066	X	-	28162770	PL21	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-1.7964537840674302	[422]	[52]	-8	hSpCas9	negative selection	10848863
53433774	53433797	X	-	28162770	PL21	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.6856893655913685	[84]	[22]	-5	hSpCas9	negative selection	10848864
53432270	53432293	X	-	28162770	PL21	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	0.43111281109081534	[454]	[266]	4	hSpCas9	negative selection	10848865
53432065	53432088	X	+	28162770	PL21	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-0.5297712221429356	[135]	[40]	-4	hSpCas9	negative selection	10848866
53431829	53431852	X	+	28162770	PL21	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.832875442738643	[220]	[26]	-8	hSpCas9	negative selection	10848867
53433861	53433884	X	-	28162770	P31FUJ	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-3.9800361340344117	[281]	[20]	-9	hSpCas9	negative selection	11018224
53433710	53433733	X	+	28162770	P31FUJ	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.564645768166824	[145]	[28]	-8	hSpCas9	negative selection	11018225
53433788	53433811	X	+	28162770	P31FUJ	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-4.132275328460414	[387]	[25]	-9	hSpCas9	negative selection	11018226
53432378	53432401	X	-	28162770	P31FUJ	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-4.574270485697386	[222]	[10]	-9	hSpCas9	negative selection	11018227
53432315	53432338	X	-	28162770	P31FUJ	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.8106752803492157	[202]	[16]	-9	hSpCas9	negative selection	11018228
53432043	53432066	X	-	28162770	P31FUJ	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-4.185135770784065	[386]	[24]	-9	hSpCas9	negative selection	11018229
53433774	53433797	X	-	28162770	P31FUJ	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.6566099133209546	[109]	[81]	-5	hSpCas9	negative selection	11018230
53432270	53432293	X	-	28162770	P31FUJ	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.7388638773886197	[506]	[356]	-5	hSpCas9	negative selection	11018231
53432065	53432088	X	+	28162770	P31FUJ	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.4789627916837762	[203]	[85]	-7	hSpCas9	negative selection	11018232
53431829	53431852	X	+	28162770	P31FUJ	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-2.2924451508417807	[320]	[76]	-8	hSpCas9	negative selection	11018233
53433861	53433884	X	-	28162770	OCIAML5	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-4.2614575070016985	[169]	[15]	-9	hSpCas9	negative selection	11187590
53433710	53433733	X	+	28162770	OCIAML5	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-0.9357244999109064	[70]	[66]	-5	hSpCas9	negative selection	11187591
53433788	53433811	X	+	28162770	OCIAML5	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-8.510278053615792	[201]	[0]	-9	hSpCas9	negative selection	11187592
53432378	53432401	X	-	28162770	OCIAML5	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-1.2554222650952056	[81]	[61]	-6	hSpCas9	negative selection	11187593
53432315	53432338	X	-	28162770	OCIAML5	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-0.8329577479162924	[74]	[75]	-5	hSpCas9	negative selection	11187594
53432043	53432066	X	-	28162770	OCIAML5	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-3.3331932606006136	[133]	[23]	-9	hSpCas9	negative selection	11187595
53433774	53433797	X	-	28162770	OCIAML5	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-2.125085065270413	[86]	[35]	-8	hSpCas9	negative selection	11187596
53432270	53432293	X	-	28162770	OCIAML5	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.5761918192567783	[260]	[315]	-4	hSpCas9	negative selection	11187597
53432065	53432088	X	+	28162770	OCIAML5	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.227575705956203	[95]	[36]	-8	hSpCas9	negative selection	11187598
53431829	53431852	X	+	28162770	OCIAML5	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-2.009607847850477	[173]	[77]	-8	hSpCas9	negative selection	11187599
53433861	53433884	X	-	28162770	EOL1	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-2.525255145868986	[447]	[40]	-8	hSpCas9	negative selection	11356956
53433710	53433733	X	+	28162770	EOL1	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-3.893075485940896	[140]	[4]	-9	hSpCas9	negative selection	11356957
53433788	53433811	X	+	28162770	EOL1	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-4.1443473096405326	[771]	[22]	-9	hSpCas9	negative selection	11356958
53432378	53432401	X	-	28162770	EOL1	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.704808848509075	[494]	[39]	-9	hSpCas9	negative selection	11356959
53432315	53432338	X	-	28162770	EOL1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.4824164271726272	[296]	[13]	-9	hSpCas9	negative selection	11356960
53432043	53432066	X	-	28162770	EOL1	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-6.92928158028657	[693]	[2]	-9	hSpCas9	negative selection	11356961
53433774	53433797	X	-	28162770	EOL1	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	0.29279105937043737	[140]	[90]	2	hSpCas9	negative selection	11356962
53432270	53432293	X	-	28162770	EOL1	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	0.03366949395064711	[559]	[301]	0	hSpCas9	negative selection	11356963
53432065	53432088	X	+	28162770	EOL1	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.1217458807034	[189]	[22]	-8	hSpCas9	negative selection	11356964
53431829	53431852	X	+	28162770	EOL1	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-0.6660612922917637	[255]	[84]	-5	hSpCas9	negative selection	11356965
53433861	53433884	X	-	28162770	MOLM13	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-3.3747027205695668	[372]	[25]	-8	hSpCas9	negative selection	11526322
53433710	53433733	X	+	28162770	MOLM13	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-6.161467238535032	[98]	[0]	-9	hSpCas9	negative selection	11526323
53433788	53433811	X	+	28162770	MOLM13	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-5.153598995201691	[639]	[12]	-9	hSpCas9	negative selection	11526324
53432378	53432401	X	-	28162770	MOLM13	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.638082987108518	[352]	[40]	-8	hSpCas9	negative selection	11526325
53432315	53432338	X	-	28162770	MOLM13	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-4.64063507523359	[206]	[5]	-9	hSpCas9	negative selection	11526326
53432043	53432066	X	-	28162770	MOLM13	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-5.35936509795073	[510]	[8]	-9	hSpCas9	negative selection	11526327
53433774	53433797	X	-	28162770	MOLM13	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.5603075102860732	[154]	[75]	-3	hSpCas9	negative selection	11526328
53432270	53432293	X	-	28162770	MOLM13	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-2.0256500914129827	[641]	[113]	-7	hSpCas9	negative selection	11526329
53432065	53432088	X	+	28162770	MOLM13	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-4.2019620167630904	[279]	[10]	-9	hSpCas9	negative selection	11526330
53431829	53431852	X	+	28162770	MOLM13	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-4.4336479795697326	[268]	[8]	-9	hSpCas9	negative selection	11526331
53433861	53433884	X	-	28162770	HEL	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-4.132554880824949	[355]	[12]	-9	hSpCas9	negative selection	11695688
53433710	53433733	X	+	28162770	HEL	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-6.390684169537093	[130]	[0]	-9	hSpCas9	negative selection	11695689
53433788	53433811	X	+	28162770	HEL	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-5.5980525001616	[604]	[7]	-9	hSpCas9	negative selection	11695690
53432378	53432401	X	-	28162770	HEL	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-3.7403894193237432	[312]	[14]	-9	hSpCas9	negative selection	11695691
53432315	53432338	X	-	28162770	HEL	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-5.513765653679634	[213]	[2]	-9	hSpCas9	negative selection	11695692
53432043	53432066	X	-	28162770	HEL	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.2938025701464184	[466]	[60]	-8	hSpCas9	negative selection	11695693
53433774	53433797	X	-	28162770	HEL	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.01845925454788455	[67]	[42]	0	hSpCas9	negative selection	11695694
53432270	53432293	X	-	28162770	HEL	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-1.7902205752757494	[485]	[89]	-7	hSpCas9	negative selection	11695695
53432065	53432088	X	+	28162770	HEL	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.284615866167877	[212]	[27]	-8	hSpCas9	negative selection	11695696
53431829	53431852	X	+	28162770	HEL	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-5.720665898863165	[246]	[2]	-9	hSpCas9	negative selection	11695697
53433861	53433884	X	-	28162770	MV411	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-4.7067587596041	[216]	[6]	-9	hSpCas9	negative selection	11865054
53433710	53433733	X	+	28162770	MV411	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-4.5495754270533695	[138]	[4]	-9	hSpCas9	negative selection	11865055
53433788	53433811	X	+	28162770	MV411	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-5.0513540453066526	[432]	[10]	-9	hSpCas9	negative selection	11865056
53432378	53432401	X	-	28162770	MV411	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-3.2473271409668025	[247]	[21]	-9	hSpCas9	negative selection	11865057
53432315	53432338	X	-	28162770	MV411	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.1372262994525495	[187]	[17]	-9	hSpCas9	negative selection	11865058
53432043	53432066	X	-	28162770	MV411	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.8098956242831763	[307]	[36]	-9	hSpCas9	negative selection	11865059
53433774	53433797	X	-	28162770	MV411	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-1.8078448847184143	[132]	[31]	-8	hSpCas9	negative selection	11865060
53432270	53432293	X	-	28162770	MV411	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.3548029413702164	[377]	[248]	-3	hSpCas9	negative selection	11865061
53432065	53432088	X	+	28162770	MV411	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-0.562459565837282	[141]	[80]	-4	hSpCas9	negative selection	11865062
53431829	53431852	X	+	28162770	MV411	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-2.0521227310761327	[191]	[38]	-8	hSpCas9	negative selection	11865063
53433861	53433884	X	-	28162770	MONOMAC1	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-4.0043917691171576	[153]	[10]	-9	hSpCas9	negative selection	12034420
53433710	53433733	X	+	28162770	MONOMAC1	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-2.3490399405046034	[79]	[17]	-9	hSpCas9	negative selection	12034421
53433788	53433811	X	+	28162770	MONOMAC1	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-3.586983365375567	[303]	[28]	-9	hSpCas9	negative selection	12034422
53432378	53432401	X	-	28162770	MONOMAC1	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-2.0164646014177325	[179]	[50]	-8	hSpCas9	negative selection	12034423
53432315	53432338	X	-	28162770	MONOMAC1	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.723582661555388	[120]	[20]	-9	hSpCas9	negative selection	12034424
53432043	53432066	X	-	28162770	MONOMAC1	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-2.4985731531157382	[280]	[56]	-9	hSpCas9	negative selection	12034425
53433774	53433797	X	-	28162770	MONOMAC1	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-1.5690056244465116	[43]	[16]	-8	hSpCas9	negative selection	12034426
53432270	53432293	X	-	28162770	MONOMAC1	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.10482047583857979	[302]	[322]	-1	hSpCas9	negative selection	12034427
53432065	53432088	X	+	28162770	MONOMAC1	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-2.0180667060142343	[105]	[29]	-8	hSpCas9	negative selection	12034428
53431829	53431852	X	+	28162770	MONOMAC1	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-0.6085684028368619	[136]	[102]	-5	hSpCas9	negative selection	12034429
53433861	53433884	X	-	28162770	OCIAML2	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-4.5775450291586735	[55]	[12]	-9	hSpCas9	negative selection	12203786
53433710	53433733	X	+	28162770	OCIAML2	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-4.9731301657713445	[16]	[2]	-9	hSpCas9	negative selection	12203787
53433788	53433811	X	+	28162770	OCIAML2	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-5.155127999514232	[89]	[13]	-9	hSpCas9	negative selection	12203788
53432378	53432401	X	-	28162770	OCIAML2	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-4.4706298252421615	[59]	[14]	-9	hSpCas9	negative selection	12203789
53432315	53432338	X	-	28162770	OCIAML2	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-3.16577524371374	[33]	[20]	-9	hSpCas9	negative selection	12203790
53432043	53432066	X	-	28162770	OCIAML2	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-3.0555923259633175	[50]	[33]	-9	hSpCas9	negative selection	12203791
53433774	53433797	X	-	28162770	OCIAML2	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-1.219091058246197	[20]	[49]	-7	hSpCas9	negative selection	12203792
53432270	53432293	X	-	28162770	OCIAML2	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	0.02376546564996662	[62]	[354]	0	hSpCas9	negative selection	12203793
53432065	53432088	X	+	28162770	OCIAML2	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-1.4507302678044562	[35]	[72]	-7	hSpCas9	negative selection	12203794
53431829	53431852	X	+	28162770	OCIAML2	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-1.2168732329963785	[25]	[61]	-7	hSpCas9	negative selection	12203795
53433861	53433884	X	-	28162770	OCIAML3	viability	CTGGTGGCGGTAATAACCGGAGG	HSD17B10	ENSG00000072506	-6.009045139603007	[63]	[2]	-9	hSpCas9	negative selection	12373152
53433710	53433733	X	+	28162770	OCIAML3	viability	GACCCCACTTACGTCGGCTGGGG	HSD17B10	ENSG00000072506	-3.8670261347305797	[28]	[5]	-9	hSpCas9	negative selection	12373153
53433788	53433811	X	+	28162770	OCIAML3	viability	CAGGTCCAGAAGCACAGCAGAGG	HSD17B10	ENSG00000072506	-5.667256622354802	[100]	[5]	-9	hSpCas9	negative selection	12373154
53432378	53432401	X	-	28162770	OCIAML3	viability	GAAGGATGTGCAAACAGCTCTGG	HSD17B10	ENSG00000072506	-4.294447358465256	[64]	[9]	-9	hSpCas9	negative selection	12373155
53432315	53432338	X	-	28162770	OCIAML3	viability	CAACTGTGCAGGCATCGCGGTGG	HSD17B10	ENSG00000072506	-2.5236183124327654	[39]	[20]	-9	hSpCas9	negative selection	12373156
53432043	53432066	X	-	28162770	OCIAML3	viability	GGCCAGAATGAACCAGACCAGGG	HSD17B10	ENSG00000072506	-3.0143394392725202	[90]	[33]	-9	hSpCas9	negative selection	12373157
53433774	53433797	X	-	28162770	OCIAML3	viability	CTGGACCTGCCCAACTCGGGTGG	HSD17B10	ENSG00000072506	-0.9501514505494386	[15]	[24]	-6	hSpCas9	negative selection	12373158
53432270	53432293	X	-	28162770	OCIAML3	viability	GAAGGGCCAGACCCATACCTTGG	HSD17B10	ENSG00000072506	-0.4193291089112162	[100]	[227]	-3	hSpCas9	negative selection	12373159
53432065	53432088	X	+	28162770	OCIAML3	viability	CCATCTCACCAGCCACCAGGCGG	HSD17B10	ENSG00000072506	-0.8284728939611863	[39]	[67]	-6	hSpCas9	negative selection	12373160
53431829	53431852	X	+	28162770	OCIAML3	viability	GGGAGCCAGATCCCGAGCAATGG	HSD17B10	ENSG00000072506	-2.699360640470392	[70]	[32]	-9	hSpCas9	negative selection	12373161