Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3315
• Symbol: HSPB1
• Description: heat shock protein family B (small) member 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HSPB1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
76302891	76302914	7	-	26472758	Jiyoye	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.3919119245681303	[86]	[49]	-3	hSpCas9	negative selection	74993
76303018	76303041	7	-	26472758	Jiyoye	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-1.2674243316999592	[82]	[25]	-7	hSpCas9	negative selection	74994
76303009	76303032	7	+	26472758	Jiyoye	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.6948718415739363	[289]	[353]	5	hSpCas9	negative selection	74995
76302790	76302813	7	-	26472758	Jiyoye	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	4.655102894949458	[0]	[18]	9	hSpCas9	negative selection	74996
76303042	76303065	7	+	26472758	Jiyoye	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	0.29755089033137533	[81]	[75]	2	hSpCas9	negative selection	74997
76303796	76303819	7	+	26472758	Jiyoye	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.4071753815058734	[13]	[27]	8	hSpCas9	negative selection	74998
76302818	76302841	7	-	26472758	Jiyoye	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.39549357645823796	[123]	[122]	3	hSpCas9	negative selection	74999
76302833	76302856	7	+	26472758	Jiyoye	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.11412840660564014	[135]	[110]	0	hSpCas9	negative selection	75000
76302941	76302964	7	+	26472758	Jiyoye	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.527121371443297	[278]	[145]	-4	hSpCas9	negative selection	75001
76302991	76303014	7	-	26472758	Jiyoye	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.06613846367080634	[208]	[164]	0	hSpCas9	negative selection	75002
76302891	76302914	7	-	26472758	KBM7	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	0.021897538902243774	[238,73]	[22,113]	0	hSpCas9	negative selection	266111
76303018	76303041	7	-	26472758	KBM7	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	0.5150786814817216	[94,93]	[1,118]	5	hSpCas9	negative selection	266112
76303009	76303032	7	+	26472758	KBM7	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.5408902716875259	[1018,687]	[591,559]	6	hSpCas9	negative selection	266113
76302790	76302813	7	-	26472758	KBM7	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.024406471213053615	[344,161]	[57,162]	0	hSpCas9	negative selection	266114
76303042	76303065	7	+	26472758	KBM7	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-1.7244253386496775	[626,407]	[45,95]	-8	hSpCas9	negative selection	266115
76303796	76303819	7	+	26472758	KBM7	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.8067172968444813	[106,83]	[147,162]	9	hSpCas9	negative selection	266116
76302818	76302841	7	-	26472758	KBM7	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.5451236382939698	[681,418]	[411,332]	6	hSpCas9	negative selection	266117
76302833	76302856	7	+	26472758	KBM7	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	-0.27895658910572235	[561,636]	[339,140]	-3	hSpCas9	negative selection	266118
76302941	76302964	7	+	26472758	KBM7	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.24588876262001114	[646,787]	[367,439]	2	hSpCas9	negative selection	266119
76302991	76303014	7	-	26472758	KBM7	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.38861062670378366	[715,614]	[229,567]	4	hSpCas9	negative selection	266120
76302891	76302914	7	-	26472758	Raji	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.6702240432899527	[95]	[13]	-5	hSpCas9	negative selection	457229
76303018	76303041	7	-	26472758	Raji	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.6999713866840049	[20]	[2]	-5	hSpCas9	negative selection	457230
76303009	76303032	7	+	26472758	Raji	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.03906003272954961	[517]	[116]	0	hSpCas9	negative selection	457231
76302790	76302813	7	-	26472758	Raji	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-1.7170449000429462	[84]	[5]	-8	hSpCas9	negative selection	457232
76303042	76303065	7	+	26472758	Raji	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.04100830451907178	[132]	[29]	0	hSpCas9	negative selection	457233
76303796	76303819	7	+	26472758	Raji	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.9451121064747223	[46]	[20]	8	hSpCas9	negative selection	457234
76302818	76302841	7	-	26472758	Raji	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.4969984377725364	[228]	[74]	5	hSpCas9	negative selection	457235
76302833	76302856	7	+	26472758	Raji	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	-0.6911744384468458	[326]	[46]	-5	hSpCas9	negative selection	457236
76302941	76302964	7	+	26472758	Raji	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.04199408866462728	[487]	[109]	0	hSpCas9	negative selection	457237
76302991	76303014	7	-	26472758	Raji	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.08652493047593512	[417]	[102]	0	hSpCas9	negative selection	457238
76302891	76302914	7	-	26472758	K562	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.9664780548321716	[124]	[53]	-5	hSpCas9	negative selection	648347
76303018	76303041	7	-	26472758	K562	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.49254686649975943	[89]	[53]	-3	hSpCas9	negative selection	648348
76303009	76303032	7	+	26472758	K562	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.2755292602064773	[733]	[749]	2	hSpCas9	negative selection	648349
76302790	76302813	7	-	26472758	K562	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.5389573314567173	[178]	[103]	-3	hSpCas9	negative selection	648350
76303042	76303065	7	+	26472758	K562	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.6718423907831355	[250]	[132]	-4	hSpCas9	negative selection	648351
76303796	76303819	7	+	26472758	K562	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.19556512874262788	[174]	[128]	-1	hSpCas9	negative selection	648352
76302818	76302841	7	-	26472758	K562	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.722559200758196	[396]	[552]	6	hSpCas9	negative selection	648353
76302833	76302856	7	+	26472758	K562	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.6739267097536239	[495]	[667]	5	hSpCas9	negative selection	648354
76302941	76302964	7	+	26472758	K562	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.21765181810366135	[543]	[533]	1	hSpCas9	negative selection	648355
76302991	76303014	7	-	26472758	K562	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.3552040797608413	[543]	[358]	-2	hSpCas9	negative selection	648356
76302784	76302807	7	+	26627737	DLD1	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.27564764195952385	[278]	[143,61,17]	-3	hSpCas9	negative selection	837109
76302991	76303014	7	-	26627737	DLD1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.34367488042491645	[689]	[280,185,339]	3	hSpCas9	negative selection	837110
76303009	76303032	7	+	26627737	DLD1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.26852714079849105	[249]	[38,121,39]	-3	hSpCas9	negative selection	837111
76303175	76303198	7	+	26627737	DLD1	viability	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.10270539387263478	[214]	[72,56,83]	1	hSpCas9	negative selection	837112
76303796	76303819	7	+	26627737	DLD1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.2672920448121956	[996]	[389,361,372]	2	hSpCas9	negative selection	837113
76302784	76302807	7	+	26627737	GBM cells	viability after 5 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.17620897384464917	[150]	[78,103]	3	hSpCas9	negative selection	919424
76302991	76303014	7	-	26627737	GBM cells	viability after 5 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.7516772938048452	[415]	[167,96]	-8	hSpCas9	negative selection	919425
76303009	76303032	7	+	26627737	GBM cells	viability after 5 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.8172931591137232	[160]	[59,37]	-8	hSpCas9	negative selection	919426
76303175	76303198	7	+	26627737	GBM cells	viability after 5 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-1.637139025354524	[115]	[13,25]	-9	hSpCas9	negative selection	919427
76303796	76303819	7	+	26627737	GBM cells	viability after 5 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.14193831998798512	[604]	[310,404]	2	hSpCas9	negative selection	919428
76302784	76302807	7	+	26627737	GBM cells	viability after 13 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.05906734706977346	[150]	[102,70]	0	hSpCas9	negative selection	1001739
76302991	76303014	7	-	26627737	GBM cells	viability after 13 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-1.1444559797123346	[415]	[100,102]	-8	hSpCas9	negative selection	1001740
76303009	76303032	7	+	26627737	GBM cells	viability after 13 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.36135091328583013	[160]	[67,67]	-4	hSpCas9	negative selection	1001741
76303175	76303198	7	+	26627737	GBM cells	viability after 13 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.43717539289496554	[115]	[51,41]	-5	hSpCas9	negative selection	1001742
76303796	76303819	7	+	26627737	GBM cells	viability after 13 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.2810780895230094	[604]	[410,388]	3	hSpCas9	negative selection	1001743
76302784	76302807	7	+	26627737	GBM cells	viability after 21 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.31353446283993336	[150]	[53,76]	-3	hSpCas9	negative selection	1084054
76302991	76303014	7	-	26627737	GBM cells	viability after 21 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-1.52517732119041	[415]	[77,78]	-8	hSpCas9	negative selection	1084055
76303009	76303032	7	+	26627737	GBM cells	viability after 21 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.08650027500947743	[160]	[96,68]	-1	hSpCas9	negative selection	1084056
76303175	76303198	7	+	26627737	GBM cells	viability after 21 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.12752612384244988	[115]	[64,50]	-1	hSpCas9	negative selection	1084057
76303796	76303819	7	+	26627737	GBM cells	viability after 21 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.19496843669113706	[604]	[393,359]	2	hSpCas9	negative selection	1084058
76302784	76302807	7	+	26627737	RPE1	viability after 9 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.0968429255891606	[710]	[184,237]	0	hSpCas9	negative selection	1166369
76302991	76303014	7	-	26627737	RPE1	viability after 9 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	1.061679150217608	[424]	[330,208]	6	hSpCas9	negative selection	1166370
76303009	76303032	7	+	26627737	RPE1	viability after 9 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.5203951740637545	[319]	[85,48]	-4	hSpCas9	negative selection	1166371
76303175	76303198	7	+	26627737	RPE1	viability after 9 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	2.4562412744833018	[120]	[306,79]	9	hSpCas9	negative selection	1166372
76303796	76303819	7	+	26627737	RPE1	viability after 9 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.37885802248086664	[1952]	[784,807]	2	hSpCas9	negative selection	1166373
76302784	76302807	7	+	26627737	RPE1	viability after 12 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.02295578395711949	[710]	[230,154]	0	hSpCas9	negative selection	1248684
76302991	76303014	7	-	26627737	RPE1	viability after 12 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.5874578942961035	[424]	[258,78]	4	hSpCas9	negative selection	1248685
76303009	76303032	7	+	26627737	RPE1	viability after 12 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.007142724061881767	[319]	[82,89]	0	hSpCas9	negative selection	1248686
76303175	76303198	7	+	26627737	RPE1	viability after 12 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	2.461984771889298	[120]	[250,102]	9	hSpCas9	negative selection	1248687
76303796	76303819	7	+	26627737	RPE1	viability after 12 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.8941894935191959	[1952]	[811,1147]	5	hSpCas9	negative selection	1248688
76302784	76302807	7	+	26627737	RPE1	viability after 15 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.12525849006245957	[710]	[189,178]	-1	hSpCas9	negative selection	1330999
76302991	76303014	7	-	26627737	RPE1	viability after 15 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	1.0593181291016416	[424]	[388,116]	6	hSpCas9	negative selection	1331000
76303009	76303032	7	+	26627737	RPE1	viability after 15 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.17263165712360684	[319]	[118,42]	-1	hSpCas9	negative selection	1331001
76303175	76303198	7	+	26627737	RPE1	viability after 15 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	2.151199626472825	[120]	[205,99]	9	hSpCas9	negative selection	1331002
76303796	76303819	7	+	26627737	RPE1	viability after 15 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.9299670900165136	[1952]	[851,1245]	5	hSpCas9	negative selection	1331003
76302784	76302807	7	+	26627737	RPE1	viability after 18 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.13281040998659763	[710]	[133,291]	0	hSpCas9	negative selection	1413314
76302991	76303014	7	-	26627737	RPE1	viability after 18 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.6199159598991677	[424]	[110,245]	4	hSpCas9	negative selection	1413315
76303009	76303032	7	+	26627737	RPE1	viability after 18 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.33692779861744404	[319]	[154,59]	2	hSpCas9	negative selection	1413316
76303175	76303198	7	+	26627737	RPE1	viability after 18 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	2.9686399975787143	[120]	[360,142]	9	hSpCas9	negative selection	1413317
76303796	76303819	7	+	26627737	RPE1	viability after 18 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.032790090212252	[1952]	[825,1347]	6	hSpCas9	negative selection	1413318
76302784	76302807	7	+	26627737	HeLa	viability after 8 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.13338777244679206	[291]	[208,116,46]	-1	hSpCas9	negative selection	1495629
76302991	76303014	7	-	26627737	HeLa	viability after 8 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.10770638117891651	[954]	[432,579,169]	-1	hSpCas9	negative selection	1495630
76303009	76303032	7	+	26627737	HeLa	viability after 8 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.8806959965457133	[296]	[68,36,101]	-7	hSpCas9	negative selection	1495631
76303175	76303198	7	+	26627737	HeLa	viability after 8 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	1.7893812321532032	[54]	[130,47,79]	9	hSpCas9	negative selection	1495632
76303796	76303819	7	+	26627737	HeLa	viability after 8 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.22450760455633367	[812]	[468,395,388]	2	hSpCas9	negative selection	1495633
76302784	76302807	7	+	26627737	HeLa	viability after 12 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.5088907101691617	[291]	[300,132,88]	4	hSpCas9	negative selection	1577944
76302991	76303014	7	-	26627737	HeLa	viability after 12 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-1.1277359374732456	[954]	[35,280,209]	-8	hSpCas9	negative selection	1577945
76303009	76303032	7	+	26627737	HeLa	viability after 12 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-1.2729504880451035	[296]	[55,17,81]	-8	hSpCas9	negative selection	1577946
76303175	76303198	7	+	26627737	HeLa	viability after 12 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	1.0487178414227603	[54]	[60,41,38]	7	hSpCas9	negative selection	1577947
76303796	76303819	7	+	26627737	HeLa	viability after 12 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.07896520709712673	[812]	[393,352,318]	0	hSpCas9	negative selection	1577948
76302784	76302807	7	+	26627737	HeLa	viability after 15 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.726038849791468	[291]	[58,69,87]	-6	hSpCas9	negative selection	1660259
76302991	76303014	7	-	26627737	HeLa	viability after 15 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.8795647761161582	[954]	[147,332,148]	-6	hSpCas9	negative selection	1660260
76303009	76303032	7	+	26627737	HeLa	viability after 15 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.21529103452763113	[296]	[134,159,124]	1	hSpCas9	negative selection	1660261
76303175	76303198	7	+	26627737	HeLa	viability after 15 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.30137450314469794	[54]	[66,2,10]	2	hSpCas9	negative selection	1660262
76303796	76303819	7	+	26627737	HeLa	viability after 15 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.1802349806403718	[812]	[150,564,414]	1	hSpCas9	negative selection	1660263
76302784	76302807	7	+	26627737	HeLa	viability after 18 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.7380241793877418	[291]	[39,55,87]	-6	hSpCas9	negative selection	1742574
76302991	76303014	7	-	26627737	HeLa	viability after 18 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.8582747152541002	[954]	[101,279,148]	-6	hSpCas9	negative selection	1742575
76303009	76303032	7	+	26627737	HeLa	viability after 18 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.17365139579687208	[296]	[87,125,124]	1	hSpCas9	negative selection	1742576
76303175	76303198	7	+	26627737	HeLa	viability after 18 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.3659749219160715	[54]	[46,2,10]	3	hSpCas9	negative selection	1742577
76303796	76303819	7	+	26627737	HeLa	viability after 18 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.18972917629305486	[812]	[93,482,414]	1	hSpCas9	negative selection	1742578
76302784	76302807	7	+	26627737	HCT116	viability after 6 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.37183090996159396	[439]	[113,75]	2	hSpCas9	negative selection	1824889
76302991	76303014	7	-	26627737	HCT116	viability after 6 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	2.12568785288873	[998]	[511,780]	9	hSpCas9	negative selection	1824890
76303009	76303032	7	+	26627737	HCT116	viability after 6 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	2.005007175193091	[207]	[361,3]	8	hSpCas9	negative selection	1824891
76303175	76303198	7	+	26627737	HCT116	viability after 6 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.8034563584972113	[342]	[242,11]	4	hSpCas9	negative selection	1824892
76303796	76303819	7	+	26627737	HCT116	viability after 6 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.8879650233833518	[2136]	[274,129]	-5	hSpCas9	negative selection	1824893
76302784	76302807	7	+	26627737	HCT116	viability after 8 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.6371220763303421	[100]	[100,78,79]	6	hSpCas9	negative selection	1907204
76302991	76303014	7	-	26627737	HCT116	viability after 8 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.2267211919204506	[579]	[272,378,466]	2	hSpCas9	negative selection	1907205
76303009	76303032	7	+	26627737	HCT116	viability after 8 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.4575630369453927	[57]	[55,41,33]	5	hSpCas9	negative selection	1907206
76303175	76303198	7	+	26627737	HCT116	viability after 8 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.2591697172434728	[110]	[73,50,28]	-3	hSpCas9	negative selection	1907207
76303796	76303819	7	+	26627737	HCT116	viability after 8 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.5634061578432836	[833]	[316,217,396]	-6	hSpCas9	negative selection	1907208
76302784	76302807	7	+	26627737	HCT116	viability after 9 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.8128410960117292	[439]	[278,148]	6	hSpCas9	negative selection	1989519
76302991	76303014	7	-	26627737	HCT116	viability after 9 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.8030768779835781	[998]	[756,234]	5	hSpCas9	negative selection	1989520
76303009	76303032	7	+	26627737	HCT116	viability after 9 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-1.1458862305364768	[207]	[47,6]	-7	hSpCas9	negative selection	1989521
76303175	76303198	7	+	26627737	HCT116	viability after 9 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-3.0766733900521257	[342]	[16,5]	-9	hSpCas9	negative selection	1989522
76303796	76303819	7	+	26627737	HCT116	viability after 9 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.7802070942409973	[2136]	[324,337]	-5	hSpCas9	negative selection	1989523
76302784	76302807	7	+	26627737	HCT116	viability after 12 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	1.4021310098474153	[100]	[121,162,137]	9	hSpCas9	negative selection	2071834
76302991	76303014	7	-	26627737	HCT116	viability after 12 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.051389007026987565	[579]	[271,256,420]	0	hSpCas9	negative selection	2071835
76303009	76303032	7	+	26627737	HCT116	viability after 12 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	1.3156767294052154	[57]	[43,99,86]	8	hSpCas9	negative selection	2071836
76303175	76303198	7	+	26627737	HCT116	viability after 12 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.0935621034546592	[110]	[98,82,1]	1	hSpCas9	negative selection	2071837
76303796	76303819	7	+	26627737	HCT116	viability after 12 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.36375164125212356	[833]	[409,309,294]	-4	hSpCas9	negative selection	2071838
76302784	76302807	7	+	26627737	HCT116	viability after 15 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.9872647252773226	[100]	[74,141,122]	8	hSpCas9	negative selection	2154149
76302991	76303014	7	-	26627737	HCT116	viability after 15 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.2794382877236262	[579]	[448,157,237]	-3	hSpCas9	negative selection	2154150
76303009	76303032	7	+	26627737	HCT116	viability after 15 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	1.066444856932666	[57]	[6,154,39]	8	hSpCas9	negative selection	2154151
76303175	76303198	7	+	26627737	HCT116	viability after 15 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.04819222611089713	[110]	[120,63,19]	0	hSpCas9	negative selection	2154152
76303796	76303819	7	+	26627737	HCT116	viability after 15 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.43331757087440304	[833]	[426,299,345]	-4	hSpCas9	negative selection	2154153
76302784	76302807	7	+	26627737	HCT116	viability after 18 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.45561107464665906	[100]	[37,94,65]	4	hSpCas9	negative selection	2236464
76302991	76303014	7	-	26627737	HCT116	viability after 18 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.24822347267829992	[579]	[313,401,275]	2	hSpCas9	negative selection	2236465
76303009	76303032	7	+	26627737	HCT116	viability after 18 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	1.1725858699082796	[57]	[37,95,52]	8	hSpCas9	negative selection	2236466
76303175	76303198	7	+	26627737	HCT116	viability after 18 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.3683679001943898	[110]	[164,36,4]	3	hSpCas9	negative selection	2236467
76303796	76303819	7	+	26627737	HCT116	viability after 18 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.326574653689677	[833]	[358,310,293]	-3	hSpCas9	negative selection	2236468
76302769	76302792	7	-	24336569	HL60	viability	GGCTATGCGGGTACCAGTCGCGG	HSPB1	ENSG00000106211	-0.20043167294140368	[637]	[1174]	-2	hSpCas9	negative selection	2270950
76302781	76302804	7	-	24336569	HL60	viability	GGTCGAAGAGGCGGCTATGCGGG	HSPB1	ENSG00000106211	0.042224711221739764	[848]	[1849]	0	hSpCas9	negative selection	2270951
76302790	76302813	7	-	24336569	HL60	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.3406500345816885	[598]	[1000]	-3	hSpCas9	negative selection	2270952
76302819	76302842	7	-	24336569	HL60	viability	CGACCACTCCTCCGGCAGCCGGG	HSPB1	ENSG00000106211	0.0246894516865257	[202]	[436]	0	hSpCas9	negative selection	2270953
76302825	76302848	7	+	24336569	HL60	viability	TGCCGGAGGAGTGGTCGCAGTGG	HSPB1	ENSG00000106211	1.5815009120935333	[29]	[189]	9	hSpCas9	negative selection	2270954
76302830	76302853	7	+	24336569	HL60	viability	GAGGAGTGGTCGCAGTGGTTAGG	HSPB1	ENSG00000106211	-0.6121306240349125	[527]	[730]	-5	hSpCas9	negative selection	2270955
76302843	76302866	7	+	24336569	HL60	viability	AGTGGTTAGGCGGCAGCAGCTGG	HSPB1	ENSG00000106211	0.6852488369313618	[791]	[2694]	6	hSpCas9	negative selection	2270956
76302848	76302871	7	+	24336569	HL60	viability	TTAGGCGGCAGCAGCTGGCCAGG	HSPB1	ENSG00000106211	-0.2699091900420065	[391]	[687]	-2	hSpCas9	negative selection	2270957
76302908	76302931	7	-	24336569	HL60	viability	TAGGCGGGCGCGGCCACTGCGGG	HSPB1	ENSG00000106211	-0.10843114822916555	[215]	[423]	-1	hSpCas9	negative selection	2270958
76302923	76302946	7	-	24336569	HL60	viability	CTGAGCGCGCGGCTGTAGGCGGG	HSPB1	ENSG00000106211	-0.38831994817832394	[487]	[788]	-3	hSpCas9	negative selection	2270959
76302769	76302792	7	-	24336569	KBM7	viability	GGCTATGCGGGTACCAGTCGCGG	HSPB1	ENSG00000106211	-0.972835451145771	[638]	[887]	-6	hSpCas9	negative selection	2338127
76302781	76302804	7	-	24336569	KBM7	viability	GGTCGAAGAGGCGGCTATGCGGG	HSPB1	ENSG00000106211	-0.7031277076001764	[1037]	[1738]	-5	hSpCas9	negative selection	2338128
76302790	76302813	7	-	24336569	KBM7	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.5052230707873195	[333]	[1292]	4	hSpCas9	negative selection	2338129
76302819	76302842	7	-	24336569	KBM7	viability	CGACCACTCCTCCGGCAGCCGGG	HSPB1	ENSG00000106211	0.6916297846801148	[268]	[1184]	6	hSpCas9	negative selection	2338130
76302825	76302848	7	+	24336569	KBM7	viability	TGCCGGAGGAGTGGTCGCAGTGG	HSPB1	ENSG00000106211	-3.2549341186064864	[90]	[25]	-9	hSpCas9	negative selection	2338131
76302830	76302853	7	+	24336569	KBM7	viability	GAGGAGTGGTCGCAGTGGTTAGG	HSPB1	ENSG00000106211	0.7585819540291496	[248]	[1148]	6	hSpCas9	negative selection	2338132
76302843	76302866	7	+	24336569	KBM7	viability	AGTGGTTAGGCGGCAGCAGCTGG	HSPB1	ENSG00000106211	0.6380698670524414	[514]	[2185]	6	hSpCas9	negative selection	2338133
76302848	76302871	7	+	24336569	KBM7	viability	TTAGGCGGCAGCAGCTGGCCAGG	HSPB1	ENSG00000106211	2.8013214670434996	[77]	[1482]	9	hSpCas9	negative selection	2338134
76302908	76302931	7	-	24336569	KBM7	viability	TAGGCGGGCGCGGCCACTGCGGG	HSPB1	ENSG00000106211	1.6762217553796686	[112]	[984]	9	hSpCas9	negative selection	2338135
76302923	76302946	7	-	24336569	KBM7	viability	CTGAGCGCGCGGCTGTAGGCGGG	HSPB1	ENSG00000106211	1.7916215124741193	[191]	[1812]	9	hSpCas9	negative selection	2338136
76302944	76302967	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	-1.1735396733061503	[2,1]	[0,0]	-9	hSpCas9	positive selection	2994394
76302724	76302747	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	0.00287691055094369	[3,2]	[3,1]	0	hSpCas9	positive selection	2994395
76302729	76302752	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	0.580287358340244	[4,4]	[3,7]	9	hSpCas9	positive selection	2994396
76302934	76302957	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	0.4513245642164893	[3,3]	[2,5]	8	hSpCas9	positive selection	2994397
76302944	76302967	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	0.4417676453552656	[2,2]	[2,1]	7	hSpCas9	positive selection	3062252
76302724	76302747	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	-0.3265653842492219	[3,3]	[2,0]	-5	hSpCas9	positive selection	3062253
76302729	76302752	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	0.03877940286556472	[4,4]	[4,2]	0	hSpCas9	positive selection	3062254
76302934	76302957	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	0.5418683931431945	[3,3]	[2,4]	8	hSpCas9	positive selection	3062255
76304007	76304030		-	24336571	A375	resistance to PLX after 7 days	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	-0.014332476466514768	[10,11]	[11,11]	0	hSpCas9	positive selection	3119994
76303791	76303814		+	24336571	A375	resistance to PLX after 7 days	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.07729943178341381	[21,16]	[18,17]	-2	hSpCas9	positive selection	3119995
76303973	76303996		+	24336571	A375	resistance to PLX after 7 days	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	0.106030933901475	[22,19]	[19,25]	3	hSpCas9	positive selection	3119996
76304007	76304030		-	24336571	A375	resistance to PLX after 14 days	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	-0.17514610867369204	[11,15]	[5,4]	-2	hSpCas9	positive selection	3177787
76303791	76303814		+	24336571	A375	resistance to PLX after 14 days	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.5134974794798598	[16,17]	[3,5]	-6	hSpCas9	positive selection	3177788
76303973	76303996		+	24336571	A375	resistance to PLX after 14 days	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	-0.6947233713947915	[19,21]	[5,4]	-7	hSpCas9	positive selection	3177789
76304007	76304030		-	24336571	A375	viability after 7 days	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	0.03352204583608992	[11]	[10,11]	0	hSpCas9	negative selection	3235580
76303791	76303814		+	24336571	A375	viability after 7 days	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.4438966158777442	[14]	[21,16]	6	hSpCas9	negative selection	3235581
76303973	76303996		+	24336571	A375	viability after 7 days	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	-0.055266870426086134	[22]	[22,19]	-1	hSpCas9	negative selection	3235582
76304007	76304030		-	24336571	A375	viability after 14 days	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	0.2739853489039247	[11]	[11,15]	3	hSpCas9	negative selection	3293373
76303791	76303814		+	24336571	A375	viability after 14 days	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.2881195795851449	[14]	[16,17]	4	hSpCas9	negative selection	3293374
76303973	76303996		+	24336571	A375	viability after 14 days	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	-0.08367322550561085	[22]	[19,21]	-1	hSpCas9	negative selection	3293375
76303992	76304015	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3373457
76304151	76304174	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	1.2349583984173806	[129,129]	[1,1]	5	hSpCas9	positive selection	3373458
76303842	76303865	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-1.5240335020788245	[439,439]	[0,0]	-8	hSpCas9	positive selection	3373459
76302943	76302966	7	+	26780180	HT29	viability (Avana library 4 designs)	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	1.17401941482917	[]	[]	4	hSpCas9	negative selection	3431722
76302724	76302747	7	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	2.63736385880262	[]	[]	8	hSpCas9	negative selection	3431723
76302728	76302751	7	+	26780180	HT29	viability (Avana library 4 designs)	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	-0.27471871674192	[]	[]	-4	hSpCas9	negative selection	3431724
76302934	76302957	7	-	26780180	HT29	viability (Avana library 4 designs)	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	0.64429837684145	[]	[]	2	hSpCas9	negative selection	3431725
76302724	76302747	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	-5.95779997651452	[]	[]	-6	hSpCas9	negative selection	3517516
76302934	76302957	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	5.9681951345722	[]	[]	9	hSpCas9	negative selection	3517517
76302728	76302751	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	4.85927597466013	[]	[]	8	hSpCas9	negative selection	3517518
76302943	76302966	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	2.49353354085064	[]	[]	4	hSpCas9	negative selection	3517519
76302818	76302841	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	2.37926673677021	[]	[]	3	hSpCas9	negative selection	3517520
76302907	76302930	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCGGGCGCGGCCACTGCGGGG	HSPB1	ENSG00000106211	-3.39419196836584	[]	[]	-4	hSpCas9	negative selection	3517521
76302724	76302747	7	-	26780180	A375	viability (Avana lentiGuide)	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	35.2050862173691	[]	[]	9	hSpCas9	negative selection	3626175
76302934	76302957	7	-	26780180	A375	viability (Avana lentiGuide)	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	-5.31339846620377	[]	[]	-8	hSpCas9	negative selection	3626176
76302728	76302751	7	+	26780180	A375	viability (Avana lentiGuide)	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	-2.40841677375404	[]	[]	-4	hSpCas9	negative selection	3626177
76302943	76302966	7	+	26780180	A375	viability (Avana lentiGuide)	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	5.00599071558462	[]	[]	4	hSpCas9	negative selection	3626178
76302818	76302841	7	-	26780180	A375	viability (Avana lentiGuide)	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	1.7093036229175	[]	[]	2	hSpCas9	negative selection	3626179
76302907	76302930	7	-	26780180	A375	viability (Avana lentiGuide)	AGGCGGGCGCGGCCACTGCGGGG	HSPB1	ENSG00000106211	-0.497870258806646	[]	[]	0	hSpCas9	negative selection	3626180
76302724	76302747	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	-0.2533693985078075	[5]	[4,3]	-4	hSpCas9	positive selection	3734834
76302934	76302957	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	0.14528936312647642	[4]	[5,4]	4	hSpCas9	positive selection	3734835
76302728	76302751	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	0.21358035142482268	[5]	[6,5]	6	hSpCas9	positive selection	3734836
76302943	76302966	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	0.4165311689524714	[3]	[4,4]	9	hSpCas9	positive selection	3734837
76302818	76302841	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.1645345818905424	[3]	[4,3]	4	hSpCas9	positive selection	3734838
76302907	76302930	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCGGGCGCGGCCACTGCGGGG	HSPB1	ENSG00000106211	-0.3131598824604748	[3]	[2,2]	-5	hSpCas9	positive selection	3734839
76302724	76302747	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGAGCGAGAAGGGGACGCGG	HSPB1	ENSG00000106211	-0.6749834922587894	[6]	[2,3]	-7	hSpCas9	positive selection	3843441
76302934	76302957	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTTGCCGGCTGAGCGCGCGG	HSPB1	ENSG00000106211	-0.3312129762341174	[5]	[5,0]	-4	hSpCas9	positive selection	3843442
76302728	76302751	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCCCTTCTCGCTCCTGCGGGG	HSPB1	ENSG00000106211	0.20215072035354759	[6]	[6,5]	5	hSpCas9	positive selection	3843443
76302943	76302966	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCCGGCAACTCAGCAGCGGGG	HSPB1	ENSG00000106211	-0.09987469644527525	[2]	[1,2]	-1	hSpCas9	positive selection	3843444
76302818	76302841	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	-0.14473369627668875	[4]	[2,4]	-2	hSpCas9	positive selection	3843445
76302907	76302930	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCGGGCGCGGCCACTGCGGGG	HSPB1	ENSG00000106211	0.052370518291903506	[4]	[3,4]	1	hSpCas9	positive selection	3843446
76303992	76304015	7	-	26780180	A375	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.629670782255688	[]	[]	2	hSpCas9	negative selection	3949446
76302927	76302950	7	+	26780180	A375	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.792331277152777	[]	[]	3	hSpCas9	negative selection	3949447
76302784	76302807	7	+	26780180	A375	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.399559204394189	[]	[]	0	hSpCas9	negative selection	3949448
76303791	76303814	7	+	26780180	A375	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	1.02399654372924	[]	[]	5	hSpCas9	negative selection	3949449
76304151	76304174	7	-	26780180	A375	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.775089628343496	[]	[]	3	hSpCas9	negative selection	3949450
76303992	76304015	7	-	26780180	HT29	viability (GeCKOv2 library)	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.613575573105802	[]	[]	2	hSpCas9	negative selection	4057412
76302927	76302950	7	+	26780180	HT29	viability (GeCKOv2 library)	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.881835749670607	[]	[]	4	hSpCas9	negative selection	4057413
76302784	76302807	7	+	26780180	HT29	viability (GeCKOv2 library)	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.589514292143828	[]	[]	2	hSpCas9	negative selection	4057414
76303791	76303814	7	+	26780180	HT29	viability (GeCKOv2 library)	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.500365992666303	[]	[]	1	hSpCas9	negative selection	4057415
76304151	76304174	7	-	26780180	HT29	viability (GeCKOv2 library)	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	1.81556029032064	[]	[]	8	hSpCas9	negative selection	4057416
76304007	76304030	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	-0.3116054724099523	[4]	[1,2]	-6	hSpCas9	positive selection	4143572
76303791	76303814	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.03879426644265112	[3]	[2,2]	-1	hSpCas9	positive selection	4143573
76303973	76303996	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	-0.17633806988143363	[3]	[1,2]	-4	hSpCas9	positive selection	4143574
76304007	76304030	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACAGGGAGGAGGAAACTTGGG	HSPB1	ENSG00000106211	-1.1377553444632056	[4]	[0,0,0,0]	-9	hSpCas9	positive selection	4207594
76303791	76303814	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.24551557710666624	[4]	[3,2,3,0]	2	hSpCas9	positive selection	4207595
76303973	76303996	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCACGTCCAGGCTGCCCCCCGG	HSPB1	ENSG00000106211	0.834716525213913	[4]	[2,3,1,3]	5	hSpCas9	positive selection	4207596
76302784	76302807	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.4653025910880484	[2]	[3,1]	8	hSpCas9	positive selection	4275980
76302927	76302950	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.13569350335932895	[2]	[3,1]	2	hSpCas9	positive selection	4275981
76303791	76303814	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.2279264759638463	[3]	[3,2]	4	hSpCas9	positive selection	4275982
76303992	76304015	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.2911104453578608	[4]	[4,3]	6	hSpCas9	positive selection	4340240
76304151	76304174	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.2534508103939296	[2]	[3,1]	5	hSpCas9	positive selection	4340241
76302894	76302916	7	-	27760321	OCIAML3	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.2150538420189686	[792,658]	[558,782]	2	hSpCas9	negative selection	4408294
76302928	76302950	7	+	27760321	OCIAML3	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.07600677097590391	[582,463]	[431,424]	0	hSpCas9	negative selection	4408295
76302968	76302990	7	+	27760321	OCIAML3	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.6170586935404558	[728,558]	[770,760]	7	hSpCas9	negative selection	4408296
76303026	76303048	7	-	27760321	OCIAML3	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.2421094778199806	[936,849]	[755,916]	3	hSpCas9	negative selection	4408297
76303842	76303864	7	-	27760321	OCIAML3	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.16385143931946816	[359,330]	[205,286]	-2	hSpCas9	negative selection	4408298
76302894	76302916	7	-	27760321	OCIAML2	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.0980802478363515	[792,658]	[511,775]	1	hSpCas9	negative selection	4491757
76302928	76302950	7	+	27760321	OCIAML2	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	-0.01190315673156947	[582,463]	[410,425]	0	hSpCas9	negative selection	4491758
76302968	76302990	7	+	27760321	OCIAML2	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.3821126459183374	[728,558]	[656,695]	5	hSpCas9	negative selection	4491759
76303026	76303048	7	-	27760321	OCIAML2	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.6827194410475068	[936,849]	[1038,1317]	8	hSpCas9	negative selection	4491760
76303842	76303864	7	-	27760321	OCIAML2	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.14993538226286657	[359,330]	[187,335]	-2	hSpCas9	negative selection	4491761
76302894	76302916	7	-	27760321	MV411	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.8617110774720222	[792,658]	[1178,397]	6	hSpCas9	negative selection	4575220
76302928	76302950	7	+	27760321	MV411	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	-0.7365256764486656	[582,463]	[66,414]	-5	hSpCas9	negative selection	4575221
76302968	76302990	7	+	27760321	MV411	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.7092363241633077	[728,558]	[645,754]	5	hSpCas9	negative selection	4575222
76303026	76303048	7	-	27760321	MV411	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.20626343941444025	[936,849]	[630,752]	1	hSpCas9	negative selection	4575223
76303842	76303864	7	-	27760321	MV411	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	0.24458328891854822	[359,330]	[359,134]	1	hSpCas9	negative selection	4575224
76302894	76302916	7	-	27760321	HL60	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.1861633526241705	[792,658]	[649,694]	2	hSpCas9	negative selection	4658683
76302928	76302950	7	+	27760321	HL60	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	1.688780004078988	[582,463]	[1379,1359]	9	hSpCas9	negative selection	4658684
76302968	76302990	7	+	27760321	HL60	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	-0.04813021732127937	[728,558]	[536,470]	0	hSpCas9	negative selection	4658685
76303026	76303048	7	-	27760321	HL60	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.488274142253071	[936,849]	[877,1176]	6	hSpCas9	negative selection	4658686
76303842	76303864	7	-	27760321	HL60	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.41945919898596357	[359,330]	[160,263]	-5	hSpCas9	negative selection	4658687
76302894	76302916	7	-	27760321	HT1080	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	-0.5755756372491883	[658,513]	[151,161]	-3	hSpCas9	negative selection	4742146
76302928	76302950	7	+	27760321	HT1080	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.8767064836567271	[463,361]	[419,172]	5	hSpCas9	negative selection	4742147
76302968	76302990	7	+	27760321	HT1080	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	1.4745273457816048	[558,435]	[523,579]	7	hSpCas9	negative selection	4742148
76303026	76303048	7	-	27760321	HT1080	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.4926061422617587	[849,662]	[265,596]	2	hSpCas9	negative selection	4742149
76303842	76303864	7	-	27760321	HT1080	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	0.16780151661231993	[330,257]	[221,32]	0	hSpCas9	negative selection	4742150
76302894	76302916	7	-	27760321	HT29	viability after 7 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.07539866329275591	[658,513]	[796,641,938]	1	hSpCas9	negative selection	4825609
76302928	76302950	7	+	27760321	HT29	viability after 7 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	-0.2739946878988612	[463,361]	[522,501,307]	-4	hSpCas9	negative selection	4825610
76302968	76302990	7	+	27760321	HT29	viability after 7 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	-0.002601040713998415	[558,435]	[745,805,385]	0	hSpCas9	negative selection	4825611
76303026	76303048	7	-	27760321	HT29	viability after 7 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.2107087296803497	[849,662]	[1185,689,697]	-3	hSpCas9	negative selection	4825612
76303842	76303864	7	-	27760321	HT29	viability after 7 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.5033260261262766	[330,257]	[282,119,395]	-6	hSpCas9	negative selection	4825613
76302894	76302916	7	-	27760321	HT29	viability after 25 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.1882215680364513	[658,513]	[875,717,679]	2	hSpCas9	negative selection	4909072
76302928	76302950	7	+	27760321	HT29	viability after 25 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.3302043844489995	[463,361]	[565,706,497]	3	hSpCas9	negative selection	4909073
76302968	76302990	7	+	27760321	HT29	viability after 25 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.892098785413331	[558,435]	[1005,983,1190]	9	hSpCas9	negative selection	4909074
76303026	76303048	7	-	27760321	HT29	viability after 25 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.15595009566881401	[849,662]	[795,523,1031]	-2	hSpCas9	negative selection	4909075
76303842	76303864	7	-	27760321	HT29	viability after 25 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.9474969304865042	[330,257]	[210,134,174]	-6	hSpCas9	negative selection	4909076
76302894	76302916	7	-	27760321	HT29	viability after 22 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.19227349296127472	[658,513]	[889,740,688]	2	hSpCas9	negative selection	4992535
76302928	76302950	7	+	27760321	HT29	viability after 22 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.06339450363851701	[463,361]	[598,492,400]	0	hSpCas9	negative selection	4992536
76302968	76302990	7	+	27760321	HT29	viability after 22 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.8632545567004316	[558,435]	[1004,1369,761]	8	hSpCas9	negative selection	4992537
76303026	76303048	7	-	27760321	HT29	viability after 22 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.10426800526999591	[849,662]	[768,629,1044]	-1	hSpCas9	negative selection	4992538
76303842	76303864	7	-	27760321	HT29	viability after 22 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.7394161714892151	[330,257]	[228,182,198]	-6	hSpCas9	negative selection	4992539
76302894	76302916	7	-	27760321	HT29	viability after 19 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	-0.006719590515616658	[658,513]	[1218,571,283]	0	hSpCas9	negative selection	5075998
76302928	76302950	7	+	27760321	HT29	viability after 19 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.4267356342260001	[463,361]	[701,539,667]	4	hSpCas9	negative selection	5075999
76302968	76302990	7	+	27760321	HT29	viability after 19 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.9972732404711461	[558,435]	[1604,1340,532]	9	hSpCas9	negative selection	5076000
76303026	76303048	7	-	27760321	HT29	viability after 19 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.15603096230497737	[849,662]	[1235,672,1008]	1	hSpCas9	negative selection	5076001
76303842	76303864	7	-	27760321	HT29	viability after 19 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-1.1589543052036644	[330,257]	[133,202,114]	-7	hSpCas9	negative selection	5076002
76302894	76302916	7	-	27760321	HT29	viability after 16 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.3875760050592112	[658,513]	[1083,869,641]	4	hSpCas9	negative selection	5159461
76302928	76302950	7	+	27760321	HT29	viability after 16 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.08124047580551597	[463,361]	[563,315,597]	0	hSpCas9	negative selection	5159462
76302968	76302990	7	+	27760321	HT29	viability after 16 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.45292261090391395	[558,435]	[675,927,668]	5	hSpCas9	negative selection	5159463
76303026	76303048	7	-	27760321	HT29	viability after 16 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.023417466725752956	[849,662]	[793,769,931]	0	hSpCas9	negative selection	5159464
76303842	76303864	7	-	27760321	HT29	viability after 16 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.4959288401669733	[330,257]	[380,70,266]	-5	hSpCas9	negative selection	5159465
76302894	76302916	7	-	27760321	HT29	viability after 13 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.4542122781810607	[658,513]	[1052,964,786]	6	hSpCas9	negative selection	5242924
76302928	76302950	7	+	27760321	HT29	viability after 13 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	-0.25646276700305276	[463,361]	[368,462,372]	-3	hSpCas9	negative selection	5242925
76302968	76302990	7	+	27760321	HT29	viability after 13 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.30086825279676765	[558,435]	[818,474,830]	4	hSpCas9	negative selection	5242926
76303026	76303048	7	-	27760321	HT29	viability after 13 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.318582078326625	[849,662]	[560,653,884]	-4	hSpCas9	negative selection	5242927
76303842	76303864	7	-	27760321	HT29	viability after 13 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-1.15951506273455	[330,257]	[131,176,149]	-8	hSpCas9	negative selection	5242928
76302894	76302916	7	-	27760321	HT29	viability after 10 days	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.0957051251960982	[658,513]	[638,880,828]	1	hSpCas9	negative selection	5326387
76302928	76302950	7	+	27760321	HT29	viability after 10 days	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	-0.3693882723055443	[463,361]	[349,572,281]	-5	hSpCas9	negative selection	5326388
76302968	76302990	7	+	27760321	HT29	viability after 10 days	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.5079382057824573	[558,435]	[690,1136,829]	7	hSpCas9	negative selection	5326389
76303026	76303048	7	-	27760321	HT29	viability after 10 days	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	-0.1871511686921643	[849,662]	[805,1027,663]	-2	hSpCas9	negative selection	5326390
76303842	76303864	7	-	27760321	HT29	viability after 10 days	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	-0.5725673146165187	[330,257]	[372,157,208]	-6	hSpCas9	negative selection	5326391
76302894	76302916	7	-	27760321	MOLM13	viability	ACTGCGGGGCTCTCGATGGCGG	HSPB1	ENSG00000106211	0.25998503824292685	[792,658]	[610,383]	1	hSpCas9	negative selection	5409850
76302928	76302950	7	+	27760321	MOLM13	viability	CTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.29593218950750666	[582,463]	[596,158]	2	hSpCas9	negative selection	5409851
76302968	76302990	7	+	27760321	MOLM13	viability	TCGGAGATCCGGCACACTGCGG	HSPB1	ENSG00000106211	0.8576100356443113	[728,558]	[1205,182]	6	hSpCas9	negative selection	5409852
76303026	76303048	7	-	27760321	MOLM13	viability	TTGACCGTCAGCTCGTCCGGGG	HSPB1	ENSG00000106211	0.7592674334473464	[936,849]	[984,739]	5	hSpCas9	negative selection	5409853
76303842	76303864	7	-	27760321	MOLM13	viability	GTATTTCCGCGTGAAGCACCGG	HSPB1	ENSG00000106211	1.2818878851210957	[359,330]	[380,552]	8	hSpCas9	negative selection	5409854
76302833	76302856	7	+	27661255	K562	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.14005560948131301	[1288,1278]	[1192,1076]	5	dCas9-KRAB	negative selection	5485760
76302957	76302980	7	+	27661255	K562	viability	GCAGCGGGGTCTCGGAGATCCGG	HSPB1	ENSG00000106211	0.33369511475347446	[347,475]	[480,353]	9	dCas9-KRAB	negative selection	5485761
76303134	76303157	7	+	27661255	K562	viability	GGGGCGTGCGGTTGAAACGGGGG	HSPB1	ENSG00000106211	0.397484870414603	[585,822]	[793,687]	9	dCas9-KRAB	negative selection	5485762
76303163	76303186	7	+	27661255	K562	viability	GGGCCTGGGGAGTTAAACGTTGG	HSPB1	ENSG00000106211	0.040268088108687206	[408,425]	[373,315]	1	dCas9-KRAB	negative selection	5485763
76303854	76303877	7	+	27661255	K562	viability	GCGGAAATACACGTGAGTCCTGG	HSPB1	ENSG00000106211	0.09319206601135388	[531,547]	[501,423]	3	dCas9-KRAB	negative selection	5485764
76302671	76302694	7	-	27661255	K562	viability	GACGTCTGCTCAGAAAAGTGCGG	HSPB1	ENSG00000106211	0.10625587672335096	[534,518]	[508,405]	3	dCas9-KRAB	negative selection	5485765
76302781	76302804	7	-	27661255	K562	viability	GGTCGAAGAGGCGGCTATGCGGG	HSPB1	ENSG00000106211	0.23568621555626787	[566,561]	[577,490]	7	dCas9-KRAB	negative selection	5485766
76303005	76303028	7	-	27661255	K562	viability	GGCGAAGTGGTTGACATCCAGGG	HSPB1	ENSG00000106211	0.1558085058456634	[615,765]	[733,508]	5	dCas9-KRAB	negative selection	5485767
76303771	76303794	7	-	27661255	K562	viability	GGAAGAGGGAAATCAGACTGCGG	HSPB1	ENSG00000106211	-0.0051383947367716065	[712,770]	[619,563]	0	dCas9-KRAB	negative selection	5485768
76303785	76303808	7	-	27661255	K562	viability	GCTTGCCTTTGGGGGGAAGAGGG	HSPB1	ENSG00000106211	-0.17253725302838374	[303,193]	[219,141]	-5	dCas9-KRAB	negative selection	5485769
76303967	76303990	7	-	27661255	K562	viability	GGCAGCCTGGACGTGCAGAGAGG	HSPB1	ENSG00000106211	0.1075452489242924	[771,1072]	[893,699]	4	dCas9-KRAB	negative selection	5485770
76302784	76302807	7	+	27260156	BXPC3	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.21334426517743943	[259]	[336,313,269,336]	5	hSpCas9	negative selection	5548440
76302927	76302950	7	+	27260156	BXPC3	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.0673782270278758	[382]	[437,373,498,358]	1	hSpCas9	negative selection	5548441
76303791	76303814	7	+	27260156	BXPC3	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.3688338807083207	[736]	[824,989,752,1479]	7	hSpCas9	negative selection	5548442
76303992	76304015	7	-	27260156	BXPC3	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.08194665755457842	[1163]	[1199,964,1466,1579]	1	hSpCas9	negative selection	5612700
76304151	76304174	7	-	27260156	BXPC3	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.11137024359317094	[361]	[426,402,338,467]	2	hSpCas9	negative selection	5612701
76302784	76302807	7	+	27260156	A673	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.13629383158407926	[259]	[329,310,440,284]	3	hSpCas9	negative selection	5669691
76302927	76302950	7	+	27260156	A673	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.30055240067660993	[382]	[570,507,576,612]	7	hSpCas9	negative selection	5669692
76303791	76303814	7	+	27260156	A673	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.00390158627052406	[736]	[896,965,817,864]	0	hSpCas9	negative selection	5669693
76303992	76304015	7	-	27260156	A673	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.039035646597611384	[1163]	[1528,1414,1283,1530]	0	hSpCas9	negative selection	5733951
76304151	76304174	7	-	27260156	A673	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	-0.04418846549221633	[361]	[435,405,356,492]	-1	hSpCas9	negative selection	5733952
76302784	76302807	7	+	27260156	A375	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.24421600950366606	[259]	[325,697,209,261]	3	hSpCas9	negative selection	5790942
76302927	76302950	7	+	27260156	A375	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.41859894207777953	[382]	[409,720,785,499]	6	hSpCas9	negative selection	5790943
76303791	76303814	7	+	27260156	A375	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.058727352403853406	[736]	[751,1041,1024,546]	-1	hSpCas9	negative selection	5790944
76303992	76304015	7	-	27260156	A375	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.009420334476500258	[1163]	[1414,1707,1272,1083]	0	hSpCas9	negative selection	5855202
76304151	76304174	7	-	27260156	A375	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.0972081180721171	[361]	[496,570,218,527]	1	hSpCas9	negative selection	5855203
76302784	76302807	7	+	27260156	COLO741	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.35064873536745045	[259]	[369,437,454]	7	hSpCas9	negative selection	5912193
76302927	76302950	7	+	27260156	COLO741	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.14832410069187907	[382]	[579,576,476]	3	hSpCas9	negative selection	5912194
76303791	76303814	7	+	27260156	COLO741	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.03902464236103309	[736]	[813,895,1020]	-1	hSpCas9	negative selection	5912195
76303992	76304015	7	-	27260156	COLO741	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.03740335257470062	[1163]	[1793,1532,1288]	0	hSpCas9	negative selection	5976453
76304151	76304174	7	-	27260156	COLO741	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.23933580450388606	[361]	[641,460,541]	5	hSpCas9	negative selection	5976454
76302784	76302807	7	+	27260156	CAL120	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.544438871811106	[259]	[488,345,580]	7	hSpCas9	negative selection	6033444
76302927	76302950	7	+	27260156	CAL120	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.6859671285231587	[382]	[835,576,894]	8	hSpCas9	negative selection	6033445
76303791	76303814	7	+	27260156	CAL120	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.39549472652861173	[736]	[1409,963,1273]	6	hSpCas9	negative selection	6033446
76303992	76304015	7	-	27260156	CAL120	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.24042011949283015	[1163]	[1372,2064,1644]	3	hSpCas9	negative selection	6097704
76304151	76304174	7	-	27260156	CAL120	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.9574561500632593	[361]	[1026,1090,534]	9	hSpCas9	negative selection	6097705
76302784	76302807	7	+	27260156	CADOES1	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.09751932281973452	[259]	[246,218,305,262]	1	hSpCas9	negative selection	6154695
76302927	76302950	7	+	27260156	CADOES1	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.3214927964171387	[382]	[432,445,495,403]	5	hSpCas9	negative selection	6154696
76303791	76303814	7	+	27260156	CADOES1	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.10699370940772357	[736]	[677,596,675,592]	-2	hSpCas9	negative selection	6154697
76303992	76304015	7	-	27260156	CADOES1	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.35941394382803726	[1163]	[1269,1763,1249,1267]	6	hSpCas9	negative selection	6218955
76304151	76304174	7	-	27260156	CADOES1	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.18241405761661567	[361]	[518,302,316,388]	3	hSpCas9	negative selection	6218956
76302784	76302807	7	+	27260156	EWS502	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.456122053936597	[259]	[350,368,348,448]	7	hSpCas9	negative selection	6275946
76302927	76302950	7	+	27260156	EWS502	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.040662763845226435	[382]	[263,435,495,495]	0	hSpCas9	negative selection	6275947
76303791	76303814	7	+	27260156	EWS502	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.18740954925235964	[736]	[884,755,772,1161]	3	hSpCas9	negative selection	6275948
76303992	76304015	7	-	27260156	EWS502	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.2259941697353498	[1163]	[1370,1159,1597,1671]	4	hSpCas9	negative selection	6340206
76304151	76304174	7	-	27260156	EWS502	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.0814152878333741	[361]	[354,350,456,471]	1	hSpCas9	negative selection	6340207
76302784	76302807	7	+	27260156	EW8	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.22124754361949606	[259]	[231,175,363,187]	4	hSpCas9	negative selection	6397197
76302927	76302950	7	+	27260156	EW8	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.37365782206929815	[382]	[492,288,358,482]	6	hSpCas9	negative selection	6397198
76303791	76303814	7	+	27260156	EW8	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.13396683447816082	[736]	[827,497,666,642]	2	hSpCas9	negative selection	6397199
76303992	76304015	7	-	27260156	EW8	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.10128964512255512	[1163]	[1284,805,939,1054]	1	hSpCas9	negative selection	6461457
76304151	76304174	7	-	27260156	EW8	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.09445282373697655	[361]	[397,346,179,358]	1	hSpCas9	negative selection	6461458
76302784	76302807	7	+	27260156	CORL105	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.33767144312274444	[259]	[495,300,421,330]	6	hSpCas9	negative selection	6518448
76302927	76302950	7	+	27260156	CORL105	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.18815528404955278	[382]	[407,516,528,587]	3	hSpCas9	negative selection	6518449
76303791	76303814	7	+	27260156	CORL105	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.12984034867691163	[736]	[995,660,795,711]	-2	hSpCas9	negative selection	6518450
76303992	76304015	7	-	27260156	CORL105	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.11690130361170059	[1163]	[1629,1322,1955,1085]	2	hSpCas9	negative selection	6582708
76304151	76304174	7	-	27260156	CORL105	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.3062179004212479	[361]	[499,352,701,570]	6	hSpCas9	negative selection	6582709
76302784	76302807	7	+	27260156	HS294T	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.49347586154735407	[259]	[114,217,98,131]	6	hSpCas9	negative selection	6639699
76302927	76302950	7	+	27260156	HS294T	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	1.0984399655326214	[382]	[412,333,239,260]	9	hSpCas9	negative selection	6639700
76303791	76303814	7	+	27260156	HS294T	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.05773023761826157	[736]	[239,232,383,343]	0	hSpCas9	negative selection	6639701
76303992	76304015	7	-	27260156	HS294T	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.5351513136619264	[1163]	[761,413,640,813]	7	hSpCas9	negative selection	6703959
76304151	76304174	7	-	27260156	HS294T	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.4754312421501917	[361]	[145,89,375,169]	6	hSpCas9	negative selection	6703960
76302784	76302807	7	+	27260156	HCC44	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.5281452097960686	[259]	[430,291,435,550]	8	hSpCas9	negative selection	6760950
76302927	76302950	7	+	27260156	HCC44	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.5358788296423443	[382]	[519,578,907,547]	8	hSpCas9	negative selection	6760951
76303791	76303814	7	+	27260156	HCC44	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.43816783742015963	[736]	[1178,1239,1110,968]	7	hSpCas9	negative selection	6760952
76303992	76304015	7	-	27260156	HCC44	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.17461863583810255	[1163]	[1630,1364,1621,1370]	2	hSpCas9	negative selection	6825210
76304151	76304174	7	-	27260156	HCC44	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.8382836339798928	[361]	[675,503,1220,635]	9	hSpCas9	negative selection	6825211
76302784	76302807	7	+	27260156	G402	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.607246315036033	[259]	[240,678,426,556]	7	hSpCas9	negative selection	6882201
76302927	76302950	7	+	27260156	G402	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.5493720582607826	[382]	[721,633,978,413]	6	hSpCas9	negative selection	6882202
76303791	76303814	7	+	27260156	G402	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.17139198169876607	[736]	[622,815,827,894]	-2	hSpCas9	negative selection	6882203
76303992	76304015	7	-	27260156	G402	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.5714851267069956	[1163]	[1959,1759,2745,1934]	7	hSpCas9	negative selection	6946461
76304151	76304174	7	-	27260156	G402	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	-0.184742513236133	[361]	[400,491,283,383]	-2	hSpCas9	negative selection	6946462
76302784	76302807	7	+	27260156	L33	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.03076436823392148	[259]	[307,93,214,182]	0	hSpCas9	negative selection	7003452
76302927	76302950	7	+	27260156	L33	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.3477786662279917	[382]	[416,207,339,485]	7	hSpCas9	negative selection	7003453
76303791	76303814	7	+	27260156	L33	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.03924869491487171	[736]	[772,298,469,617]	-1	hSpCas9	negative selection	7003454
76303992	76304015	7	-	27260156	L33	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.3932167134092228	[1163]	[962,286,608,910]	-7	hSpCas9	negative selection	7067712
76304151	76304174	7	-	27260156	L33	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.19401276770665885	[361]	[400,217,266,299]	4	hSpCas9	negative selection	7067713
76302784	76302807	7	+	27260156	K562	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.46037213758839907	[259]	[332,285,207,427]	6	hSpCas9	negative selection	7124703
76302927	76302950	7	+	27260156	K562	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	1.0652780473608372	[382]	[588,337,1359,544]	9	hSpCas9	negative selection	7124704
76303791	76303814	7	+	27260156	K562	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.224509382087492	[736]	[386,821,784,275]	-3	hSpCas9	negative selection	7124705
76303992	76304015	7	-	27260156	K562	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.36392213807711093	[1163]	[1114,1405,1483,1296]	4	hSpCas9	negative selection	7188963
76304151	76304174	7	-	27260156	K562	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.10931130736784989	[361]	[644,251,215,296]	1	hSpCas9	negative selection	7188964
76302784	76302807	7	+	27260156	HT29	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.3925427764085455	[259]	[446,511,424,297]	7	hSpCas9	negative selection	7245954
76302927	76302950	7	+	27260156	HT29	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.24595511726659586	[382]	[533,611,615,457]	5	hSpCas9	negative selection	7245955
76303791	76303814	7	+	27260156	HT29	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.3327557653070097	[736]	[1180,1529,1129,749]	6	hSpCas9	negative selection	7245956
76303992	76304015	7	-	27260156	HT29	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.13262503330302566	[1163]	[1887,1656,1450,1267]	2	hSpCas9	negative selection	7310214
76304151	76304174	7	-	27260156	HT29	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.04334344199665574	[361]	[444,473,450,442]	0	hSpCas9	negative selection	7310215
76302784	76302807	7	+	27260156	MHHES1	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.3282287484060167	[259]	[546,478,204,282]	6	hSpCas9	negative selection	7367205
76302927	76302950	7	+	27260156	MHHES1	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.16858142836933085	[382]	[417,505,663,363]	3	hSpCas9	negative selection	7367206
76303791	76303814	7	+	27260156	MHHES1	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.11892097398500234	[736]	[748,868,863,604]	-2	hSpCas9	negative selection	7367207
76303992	76304015	7	-	27260156	MHHES1	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.10121392427521347	[1163]	[1689,1272,907,1081]	-2	hSpCas9	negative selection	7431465
76304151	76304174	7	-	27260156	MHHES1	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.051367379778430866	[361]	[570,438,358,347]	1	hSpCas9	negative selection	7431466
76302784	76302807	7	+	27260156	MEWO	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.22854178693000615	[259]	[279,277,295]	5	hSpCas9	negative selection	7488456
76302927	76302950	7	+	27260156	MEWO	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.204074817483892	[382]	[621,359,296]	4	hSpCas9	negative selection	7488457
76303791	76303814	7	+	27260156	MEWO	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.031155896625787327	[736]	[810,734,587]	0	hSpCas9	negative selection	7488458
76303992	76304015	7	-	27260156	MEWO	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.14889573993566274	[1163]	[1476,1029,1167]	3	hSpCas9	negative selection	7552716
76304151	76304174	7	-	27260156	MEWO	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.3981676190528743	[361]	[590,420,354]	8	hSpCas9	negative selection	7552717
76302784	76302807	7	+	27260156	LNCAPCLONEFGC	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.6116643871889759	[259]	[302,436,303,382]	8	hSpCas9	negative selection	7609707
76302927	76302950	7	+	27260156	LNCAPCLONEFGC	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.40607947173631936	[382]	[567,438,426,398]	6	hSpCas9	negative selection	7609708
76303791	76303814	7	+	27260156	LNCAPCLONEFGC	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.03592818293575084	[736]	[703,539,862,665]	0	hSpCas9	negative selection	7609709
76303992	76304015	7	-	27260156	LNCAPCLONEFGC	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.19405567294598813	[1163]	[1257,974,1378,1251]	3	hSpCas9	negative selection	7673967
76304151	76304174	7	-	27260156	LNCAPCLONEFGC	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.5419955625721401	[361]	[434,366,614,520]	8	hSpCas9	negative selection	7673968
76302784	76302807	7	+	27260156	PANC0327	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.4506064701584267	[259]	[441,234,219,385]	6	hSpCas9	negative selection	7730958
76302927	76302950	7	+	27260156	PANC0327	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.22285608009854024	[382]	[362,615,320,256]	3	hSpCas9	negative selection	7730959
76303791	76303814	7	+	27260156	PANC0327	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.0676161068206349	[736]	[703,610,559,879]	1	hSpCas9	negative selection	7730960
76303992	76304015	7	-	27260156	PANC0327	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.16427014622527913	[1163]	[1145,1052,797,694]	-2	hSpCas9	negative selection	7795218
76304151	76304174	7	-	27260156	PANC0327	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.4276111857412393	[361]	[430,302,260,750]	6	hSpCas9	negative selection	7795219
76302784	76302807	7	+	27260156	NCIH2009	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.29397940058616934	[259]	[535,348,469]	4	hSpCas9	negative selection	7852209
76302927	76302950	7	+	27260156	NCIH2009	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.4471661587270007	[382]	[734,590,864]	6	hSpCas9	negative selection	7852210
76303791	76303814	7	+	27260156	NCIH2009	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.19631643742948002	[736]	[1598,918,1106]	2	hSpCas9	negative selection	7852211
76303992	76304015	7	-	27260156	NCIH2009	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.2524870674334587	[1163]	[1482,1228,1406]	-3	hSpCas9	negative selection	7916469
76304151	76304174	7	-	27260156	NCIH2009	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.4035379793469649	[361]	[841,452,748]	5	hSpCas9	negative selection	7916470
76302784	76302807	7	+	27260156	NCIH1373	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.2944367337553342	[259]	[859,262,185,52]	3	hSpCas9	negative selection	7973460
76302927	76302950	7	+	27260156	NCIH1373	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.4309174668906033	[382]	[567,479,635,167]	4	hSpCas9	negative selection	7973461
76303791	76303814	7	+	27260156	NCIH1373	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.4171362468870436	[736]	[585,461,761,176]	-4	hSpCas9	negative selection	7973462
76303992	76304015	7	-	27260156	NCIH1373	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.23213410615064434	[1163]	[2143,1124,1519,385]	2	hSpCas9	negative selection	8037720
76304151	76304174	7	-	27260156	NCIH1373	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.18769098709247617	[361]	[733,533,329,71]	1	hSpCas9	negative selection	8037721
76302784	76302807	7	+	27260156	PATU8902	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.43837310668197854	[259]	[490,342,540,580]	4	hSpCas9	negative selection	8094711
76302927	76302950	7	+	27260156	PATU8902	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.8812607335739304	[382]	[760,1105,866,1253]	8	hSpCas9	negative selection	8094712
76303791	76303814	7	+	27260156	PATU8902	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.4020748115970434	[736]	[919,1918,1175,1466]	4	hSpCas9	negative selection	8094713
76303992	76304015	7	-	27260156	PATU8902	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.4571920786575503	[1163]	[1694,2398,2039,2884]	5	hSpCas9	negative selection	8158971
76304151	76304174	7	-	27260156	PATU8902	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.5262149716149414	[361]	[449,750,667,1091]	5	hSpCas9	negative selection	8158972
76302784	76302807	7	+	27260156	PANC1	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.19298668917442097	[259]	[366,279,186,194]	3	hSpCas9	negative selection	8215962
76302927	76302950	7	+	27260156	PANC1	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.308262730783679	[382]	[387,629,398,273]	5	hSpCas9	negative selection	8215963
76303791	76303814	7	+	27260156	PANC1	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.21968448475928826	[736]	[796,724,799,628]	3	hSpCas9	negative selection	8215964
76303992	76304015	7	-	27260156	PANC1	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.1091079546930045	[1163]	[973,1242,1049,1065]	1	hSpCas9	negative selection	8280222
76304151	76304174	7	-	27260156	PANC1	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.35711329255536806	[361]	[368,457,571,229]	6	hSpCas9	negative selection	8280223
76302784	76302807	7	+	27260156	PANC0813	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.655441568262231	[259]	[590,438,382,517]	9	hSpCas9	negative selection	8337213
76302927	76302950	7	+	27260156	PANC0813	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.5308807196603833	[382]	[644,734,481,730]	8	hSpCas9	negative selection	8337214
76303791	76303814	7	+	27260156	PANC0813	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.37568773729802896	[736]	[1057,1058,1371,1003]	6	hSpCas9	negative selection	8337215
76303992	76304015	7	-	27260156	PANC0813	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.06582557562955471	[1163]	[1662,1349,1265,1461]	1	hSpCas9	negative selection	8401473
76304151	76304174	7	-	27260156	PANC0813	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	-0.2000460660761212	[361]	[402,348,342,386]	-3	hSpCas9	negative selection	8401474
76302784	76302807	7	+	27260156	RDES	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.265298576052979	[259]	[297,342,351,463]	4	hSpCas9	negative selection	8458464
76302927	76302950	7	+	27260156	RDES	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.1587776125716788	[382]	[438,436,655,432]	2	hSpCas9	negative selection	8458465
76303791	76303814	7	+	27260156	RDES	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.263847158159223	[736]	[548,793,700,796]	-4	hSpCas9	negative selection	8458466
76303992	76304015	7	-	27260156	RDES	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.15272500338582073	[1163]	[1291,1466,1619,1590]	2	hSpCas9	negative selection	8522724
76304151	76304174	7	-	27260156	RDES	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	-0.0821467943958914	[361]	[399,421,421,296]	-1	hSpCas9	negative selection	8522725
76302784	76302807	7	+	27260156	PC3	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.34326167392491536	[259]	[258,234,451,417]	7	hSpCas9	negative selection	8579715
76302927	76302950	7	+	27260156	PC3	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.0023148487337429358	[382]	[261,325,569,463]	0	hSpCas9	negative selection	8579716
76303791	76303814	7	+	27260156	PC3	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.3101239761984135	[736]	[750,709,1526,861]	6	hSpCas9	negative selection	8579717
76303992	76304015	7	-	27260156	PC3	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.1349015902002828	[1163]	[944,1220,2075,1163]	3	hSpCas9	negative selection	8643975
76304151	76304174	7	-	27260156	PC3	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.26238162743284266	[361]	[258,357,934,414]	6	hSpCas9	negative selection	8643976
76302784	76302807	7	+	27260156	PATU8988T	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.4016191021359592	[259]	[326,297,325,376]	6	hSpCas9	negative selection	8700966
76302927	76302950	7	+	27260156	PATU8988T	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.45162872815665744	[382]	[297,758,576,404]	7	hSpCas9	negative selection	8700967
76303791	76303814	7	+	27260156	PATU8988T	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.08168839442594733	[736]	[687,759,853,707]	1	hSpCas9	negative selection	8700968
76303992	76304015	7	-	27260156	PATU8988T	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.07065383781093693	[1163]	[986,1435,1154,1169]	1	hSpCas9	negative selection	8765226
76304151	76304174	7	-	27260156	PATU8988T	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	-0.11724494550524511	[361]	[356,197,303,427]	-2	hSpCas9	negative selection	8765227
76302784	76302807	7	+	27260156	T47D	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.2653351438150602	[259]	[360,346,389,358]	5	hSpCas9	negative selection	8822217
76302927	76302950	7	+	27260156	T47D	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.4381208405576463	[382]	[782,516,634,486]	8	hSpCas9	negative selection	8822218
76303791	76303814	7	+	27260156	T47D	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.002773591689849142	[736]	[862,838,823,918]	0	hSpCas9	negative selection	8822219
76303992	76304015	7	-	27260156	T47D	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.09717042210239701	[1163]	[1415,1253,1627,1519]	2	hSpCas9	negative selection	8886477
76304151	76304174	7	-	27260156	T47D	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.24679183940989366	[361]	[513,505,527,450]	5	hSpCas9	negative selection	8886478
76302784	76302807	7	+	27260156	SU8686	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.5014175276837889	[259]	[319,369,298,490]	8	hSpCas9	negative selection	8943468
76302927	76302950	7	+	27260156	SU8686	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.518678276254879	[382]	[397,472,638,718]	8	hSpCas9	negative selection	8943469
76303791	76303814	7	+	27260156	SU8686	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.2751555680435698	[736]	[1011,668,939,931]	5	hSpCas9	negative selection	8943470
76303992	76304015	7	-	27260156	SU8686	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.10529855356832796	[1163]	[1041,967,1037,1285]	-2	hSpCas9	negative selection	9007728
76304151	76304174	7	-	27260156	SU8686	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.21621339330616757	[361]	[393,404,383,497]	3	hSpCas9	negative selection	9007729
76302784	76302807	7	+	27260156	SKES1	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.32943689565723255	[259]	[344,378,363,231]	7	hSpCas9	negative selection	9064719
76302927	76302950	7	+	27260156	SKES1	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.0380093869096908	[382]	[485,376,394,325]	0	hSpCas9	negative selection	9064720
76303791	76303814	7	+	27260156	SKES1	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.03556024525626078	[736]	[1018,599,550,720]	0	hSpCas9	negative selection	9064721
76303992	76304015	7	-	27260156	SKES1	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.058893166148313414	[1163]	[1038,1448,1400,967]	1	hSpCas9	negative selection	9128979
76304151	76304174	7	-	27260156	SKES1	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.14360145374026953	[361]	[347,386,487,362]	3	hSpCas9	negative selection	9128980
76302784	76302807	7	+	27260156	TOV112D	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-0.0548054823719375	[259]	[166,352,267,232]	-1	hSpCas9	negative selection	9185970
76302927	76302950	7	+	27260156	TOV112D	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.5216289500920634	[382]	[543,573,647,443]	8	hSpCas9	negative selection	9185971
76303791	76303814	7	+	27260156	TOV112D	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.10832511816552426	[736]	[768,894,603,532]	-2	hSpCas9	negative selection	9185972
76303992	76304015	7	-	27260156	TOV112D	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.2395102907450395	[1163]	[1343,1234,1235,1642]	4	hSpCas9	negative selection	9250230
76304151	76304174	7	-	27260156	TOV112D	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.22006076935266952	[361]	[385,400,462,429]	4	hSpCas9	negative selection	9250231
76302784	76302807	7	+	27260156	TC71	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.15124289455904416	[259]	[293,277,323,343]	4	hSpCas9	negative selection	9307221
76302927	76302950	7	+	27260156	TC71	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.1681984316956128	[382]	[393,518,465,467]	4	hSpCas9	negative selection	9307222
76303791	76303814	7	+	27260156	TC71	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	0.046183735542978166	[736]	[797,860,789,814]	1	hSpCas9	negative selection	9307223
76303992	76304015	7	-	27260156	TC71	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	-0.0300709984517864	[1163]	[1230,1245,1226,1180]	0	hSpCas9	negative selection	9371481
76304151	76304174	7	-	27260156	TC71	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.0890067280288504	[361]	[281,477,395,503]	2	hSpCas9	negative selection	9371482
76302784	76302807	7	+	27260156	TC32	viability	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.33359224334475035	[259]	[237,194,456,407]	6	hSpCas9	negative selection	9428472
76302927	76302950	7	+	27260156	TC32	viability	CCTACAGCCGCGCGCTCAGCCGG	HSPB1	ENSG00000106211	0.6170503582369324	[382]	[436,596,608,534]	8	hSpCas9	negative selection	9428473
76303791	76303814	7	+	27260156	TC32	viability	TCCCCCCAAAGGCAAGCACGAGG	HSPB1	ENSG00000106211	-0.16822754117204314	[736]	[447,573,740,729]	-3	hSpCas9	negative selection	9428474
76303992	76304015	7	-	27260156	TC32	viability	AACTTGGGTGGGGTCCACACCGG	HSPB1	ENSG00000106211	0.12808260678090866	[1163]	[950,932,1597,1443]	2	hSpCas9	negative selection	9492732
76304151	76304174	7	-	27260156	TC32	viability	TTACTTGGCGGCAGTCTCATCGG	HSPB1	ENSG00000106211	0.14670162752432428	[361]	[419,244,506,378]	2	hSpCas9	negative selection	9492733
76302784	76302807	7	+	27869803	HPAFII	viability after 27 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.6368589360218595	[131]	[144,76,NaN]	5	hSpCas9	negative selection	9600215
76302991	76303014	7	-	27869803	HPAFII	viability after 27 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-1.0791611235033516	[467]	[14,200,NaN]	-6	hSpCas9	negative selection	9600216
76303009	76303032	7	+	27869803	HPAFII	viability after 27 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-1.551087383124511	[150]	[1,47,NaN]	-7	hSpCas9	negative selection	9600217
76303175	76303198	7	+	27869803	HPAFII	viability after 27 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.6620737416701745	[83]	[4,46,NaN]	-5	hSpCas9	negative selection	9600218
76303796	76303819	7	+	27869803	HPAFII	viability after 27 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.08107779450108388	[578]	[429,231,NaN]	0	hSpCas9	negative selection	9600219
76302784	76302807	7	+	27869803	HPAFII	viability after 15 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.5342168050790956	[131]	[292,150,NaN]	6	hSpCas9	negative selection	9682664
76302991	76303014	7	-	27869803	HPAFII	viability after 15 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.17843129123846047	[467]	[367,491,NaN]	-2	hSpCas9	negative selection	9682665
76303009	76303032	7	+	27869803	HPAFII	viability after 15 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-1.7253302208439565	[150]	[8,73,NaN]	-9	hSpCas9	negative selection	9682666
76303175	76303198	7	+	27869803	HPAFII	viability after 15 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.06526298984333256	[83]	[97,78,NaN]	0	hSpCas9	negative selection	9682667
76303796	76303819	7	+	27869803	HPAFII	viability after 15 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.02000542172796238	[578]	[1233,255,NaN]	0	hSpCas9	negative selection	9682668
76302784	76302807	7	+	27869803	ASPC1	viability after 36 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	-1.0478873577247851	[330]	[78,89,11]	-7	hSpCas9	negative selection	9765113
76302991	76303014	7	-	27869803	ASPC1	viability after 36 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.8345245947618478	[948]	[954,722,223]	7	hSpCas9	negative selection	9765114
76303009	76303032	7	+	27869803	ASPC1	viability after 36 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.34394626519852	[322]	[26,194,46]	-4	hSpCas9	negative selection	9765115
76303175	76303198	7	+	27869803	ASPC1	viability after 36 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	0.08625959445129183	[229]	[26,218,18]	0	hSpCas9	negative selection	9765116
76303796	76303819	7	+	27869803	ASPC1	viability after 36 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.8647744695346081	[1594]	[537,80,317]	-7	hSpCas9	negative selection	9765117
76302784	76302807	7	+	27869803	PATU8988S	viability after 35 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.4216083575536957	[331]	[221,135,NaN]	5	hSpCas9	negative selection	9847562
76302991	76303014	7	-	27869803	PATU8988S	viability after 35 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.13012189313269362	[889]	[514,268,NaN]	1	hSpCas9	negative selection	9847563
76303009	76303032	7	+	27869803	PATU8988S	viability after 35 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.3077082480025609	[264]	[176,86,NaN]	3	hSpCas9	negative selection	9847564
76303175	76303198	7	+	27869803	PATU8988S	viability after 35 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.849202794604071	[207]	[46,45,NaN]	-7	hSpCas9	negative selection	9847565
76303796	76303819	7	+	27869803	PATU8988S	viability after 35 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.13104241205222955	[1266]	[455,475,NaN]	-1	hSpCas9	negative selection	9847566
76302784	76302807	7	+	27869803	PATU8988S	viability after 31 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	0.25822830086916554	[331]	[211,89,NaN]	3	hSpCas9	negative selection	9930011
76302991	76303014	7	-	27869803	PATU8988S	viability after 31 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.2236905949957576	[889]	[420,405,NaN]	2	hSpCas9	negative selection	9930012
76303009	76303032	7	+	27869803	PATU8988S	viability after 31 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.5427252474655743	[264]	[189,107,NaN]	6	hSpCas9	negative selection	9930013
76303175	76303198	7	+	27869803	PATU8988S	viability after 31 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.2389991336453554	[207]	[53,90,NaN]	-3	hSpCas9	negative selection	9930014
76303796	76303819	7	+	27869803	PATU8988S	viability after 31 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.10929979251608946	[1266]	[404,548,NaN]	-1	hSpCas9	negative selection	9930015
76302784	76302807	7	+	27869803	HPAFII	viability after 35 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	1.2014043506059233	[131]	[203,96,NaN]	7	hSpCas9	negative selection	10012460
76302991	76303014	7	-	27869803	HPAFII	viability after 35 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.5861204208176415	[467]	[35,294,NaN]	-4	hSpCas9	negative selection	10012461
76303009	76303032	7	+	27869803	HPAFII	viability after 35 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-2.169524366039412	[150]	[0,34,NaN]	-8	hSpCas9	negative selection	10012462
76303175	76303198	7	+	27869803	HPAFII	viability after 35 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.9433000286126387	[83]	[15,28,NaN]	-5	hSpCas9	negative selection	10012463
76303796	76303819	7	+	27869803	HPAFII	viability after 35 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.014392061264350886	[578]	[407,169,NaN]	0	hSpCas9	negative selection	10012464
76302784	76302807	7	+	27869803	HPAFII	viability after 31 days	GCATAGCCGCCTCTTCGACCAGG	HSPB1	ENSG00000106211	1.0522798196473058	[131]	[189,113,NaN]	7	hSpCas9	negative selection	10094909
76302991	76303014	7	-	27869803	HPAFII	viability after 31 days	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-1.3472949974206698	[467]	[18,194,NaN]	-7	hSpCas9	negative selection	10094910
76303009	76303032	7	+	27869803	HPAFII	viability after 31 days	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-1.765305235497773	[150]	[0,50,NaN]	-7	hSpCas9	negative selection	10094911
76303175	76303198	7	+	27869803	HPAFII	viability after 31 days	TTAAACGTTGGCCCAGCACCGGG	HSPB1	ENSG00000106211	-0.07905050190648955	[83]	[13,77,NaN]	0	hSpCas9	negative selection	10094912
76303796	76303819	7	+	27869803	HPAFII	viability after 31 days	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.20070157028257563	[578]	[343,215,NaN]	-1	hSpCas9	negative selection	10094913
76302891	76302914	7	-	28162770	P31FUJ	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.42262676329439586	[72]	[63]	-4	hSpCas9	negative selection	10171787
76303018	76303041	7	-	28162770	P31FUJ	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.35309643813209046	[49]	[45]	-3	hSpCas9	negative selection	10171788
76303009	76303032	7	+	28162770	P31FUJ	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.3016012013996824	[407]	[388]	-3	hSpCas9	negative selection	10171789
76302790	76302813	7	-	28162770	P31FUJ	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.33971740833089026	[41]	[38]	-3	hSpCas9	negative selection	10171790
76303042	76303065	7	+	28162770	P31FUJ	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-2.351743277137886	[138]	[31]	-8	hSpCas9	negative selection	10171791
76303796	76303819	7	+	28162770	P31FUJ	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.5126249685000237	[33]	[113]	9	hSpCas9	negative selection	10171792
76302818	76302841	7	-	28162770	P31FUJ	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	-0.1105962720412077	[361]	[393]	-1	hSpCas9	negative selection	10171793
76302833	76302856	7	+	28162770	P31FUJ	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.33130169140911303	[208]	[308]	3	hSpCas9	negative selection	10171794
76302941	76302964	7	+	28162770	P31FUJ	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.23072216885680152	[511]	[705]	2	hSpCas9	negative selection	10171795
76302991	76303014	7	-	28162770	P31FUJ	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.5574932015969682	[391]	[312]	-5	hSpCas9	negative selection	10171796
76302891	76302914	7	-	28162770	TF1	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10341153
76303018	76303041	7	-	28162770	TF1	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10341154
76303009	76303032	7	+	28162770	TF1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[297]	1	hSpCas9	negative selection	10341155
76302790	76302813	7	-	28162770	TF1	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10341156
76303042	76303065	7	+	28162770	TF1	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10341157
76303796	76303819	7	+	28162770	TF1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10341158
76302818	76302841	7	-	28162770	TF1	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	NaN	[NaN]	[452]	1	hSpCas9	negative selection	10341159
76302833	76302856	7	+	28162770	TF1	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10341160
76302941	76302964	7	+	28162770	TF1	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[338]	1	hSpCas9	negative selection	10341161
76302991	76303014	7	-	28162770	TF1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	NaN	[NaN]	[446]	1	hSpCas9	negative selection	10341162
76302891	76302914	7	-	28162770	SKM1	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	1.3277454214826765	[15]	[70]	9	hSpCas9	negative selection	10510519
76303018	76303041	7	-	28162770	SKM1	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	0.5472321116437138	[11]	[30]	5	hSpCas9	negative selection	10510520
76303009	76303032	7	+	28162770	SKM1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.679747434450169	[112]	[319]	6	hSpCas9	negative selection	10510521
76302790	76302813	7	-	28162770	SKM1	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	2.0039689022029457	[21]	[155]	9	hSpCas9	negative selection	10510522
76303042	76303065	7	+	28162770	SKM1	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-1.1845717774067137	[35]	[27]	-7	hSpCas9	negative selection	10510523
76303796	76303819	7	+	28162770	SKM1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.3150417093021227	[18]	[26]	-3	hSpCas9	negative selection	10510524
76302818	76302841	7	-	28162770	SKM1	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.5378942470643774	[89]	[230]	5	hSpCas9	negative selection	10510525
76302833	76302856	7	+	28162770	SKM1	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.32001730685042235	[57]	[127]	3	hSpCas9	negative selection	10510526
76302941	76302964	7	+	28162770	SKM1	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.5699384100092146	[109]	[130]	-4	hSpCas9	negative selection	10510527
76302991	76303014	7	-	28162770	SKM1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.4939026092375868	[95]	[238]	5	hSpCas9	negative selection	10510528
76302891	76302914	7	-	28162770	SKM1	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	1.3277454214826765	[15]	[70]	9	hSpCas9	negative selection	10679885
76303018	76303041	7	-	28162770	SKM1	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	0.5472321116437138	[11]	[30]	5	hSpCas9	negative selection	10679886
76303009	76303032	7	+	28162770	SKM1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.679747434450169	[112]	[319]	6	hSpCas9	negative selection	10679887
76302790	76302813	7	-	28162770	SKM1	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	2.0039689022029457	[21]	[155]	9	hSpCas9	negative selection	10679888
76303042	76303065	7	+	28162770	SKM1	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-1.1845717774067137	[35]	[27]	-7	hSpCas9	negative selection	10679889
76303796	76303819	7	+	28162770	SKM1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.3150417093021227	[18]	[26]	-3	hSpCas9	negative selection	10679890
76302818	76302841	7	-	28162770	SKM1	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.5378942470643774	[89]	[230]	5	hSpCas9	negative selection	10679891
76302833	76302856	7	+	28162770	SKM1	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.32001730685042235	[57]	[127]	3	hSpCas9	negative selection	10679892
76302941	76302964	7	+	28162770	SKM1	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.5699384100092146	[109]	[130]	-4	hSpCas9	negative selection	10679893
76302991	76303014	7	-	28162770	SKM1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.4939026092375868	[95]	[238]	5	hSpCas9	negative selection	10679894
76302891	76302914	7	-	28162770	PL21	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.27379157384309205	[74]	[26]	-2	hSpCas9	negative selection	10849251
76303018	76303041	7	-	28162770	PL21	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-4.259292004147977	[43]	[0]	-9	hSpCas9	negative selection	10849252
76303009	76303032	7	+	28162770	PL21	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.3491772494578087	[486]	[269]	3	hSpCas9	negative selection	10849253
76302790	76302813	7	-	28162770	PL21	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-2.214897884789524	[63]	[5]	-8	hSpCas9	negative selection	10849254
76303042	76303065	7	+	28162770	PL21	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.7258598040669032	[151]	[39]	-5	hSpCas9	negative selection	10849255
76303796	76303819	7	+	28162770	PL21	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.8600641728916985	[49]	[78]	9	hSpCas9	negative selection	10849256
76302818	76302841	7	-	28162770	PL21	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.04813652104427013	[279]	[125]	0	hSpCas9	negative selection	10849257
76302833	76302856	7	+	28162770	PL21	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.5669219451609429	[151]	[97]	5	hSpCas9	negative selection	10849258
76302941	76302964	7	+	28162770	PL21	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.5246963679372971	[328]	[205]	4	hSpCas9	negative selection	10849259
76302991	76303014	7	-	28162770	PL21	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.3285546665850909	[351]	[121]	-2	hSpCas9	negative selection	10849260
76302891	76302914	7	-	28162770	P31FUJ	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.42262676329439586	[72]	[63]	-4	hSpCas9	negative selection	11018617
76303018	76303041	7	-	28162770	P31FUJ	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.35309643813209046	[49]	[45]	-3	hSpCas9	negative selection	11018618
76303009	76303032	7	+	28162770	P31FUJ	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.3016012013996824	[407]	[388]	-3	hSpCas9	negative selection	11018619
76302790	76302813	7	-	28162770	P31FUJ	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.33971740833089026	[41]	[38]	-3	hSpCas9	negative selection	11018620
76303042	76303065	7	+	28162770	P31FUJ	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-2.351743277137886	[138]	[31]	-8	hSpCas9	negative selection	11018621
76303796	76303819	7	+	28162770	P31FUJ	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.5126249685000237	[33]	[113]	9	hSpCas9	negative selection	11018622
76302818	76302841	7	-	28162770	P31FUJ	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	-0.1105962720412077	[361]	[393]	-1	hSpCas9	negative selection	11018623
76302833	76302856	7	+	28162770	P31FUJ	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.33130169140911303	[208]	[308]	3	hSpCas9	negative selection	11018624
76302941	76302964	7	+	28162770	P31FUJ	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.23072216885680152	[511]	[705]	2	hSpCas9	negative selection	11018625
76302991	76303014	7	-	28162770	P31FUJ	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.5574932015969682	[391]	[312]	-5	hSpCas9	negative selection	11018626
76302891	76302914	7	-	28162770	OCIAML5	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	0.06547126894403021	[26]	[50]	0	hSpCas9	negative selection	11187983
76303018	76303041	7	-	28162770	OCIAML5	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.2534291332457643	[34]	[52]	-2	hSpCas9	negative selection	11187984
76303009	76303032	7	+	28162770	OCIAML5	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.5780103278789877	[166]	[449]	5	hSpCas9	negative selection	11187985
76302790	76302813	7	-	28162770	OCIAML5	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.5325972793713278	[17]	[46]	4	hSpCas9	negative selection	11187986
76303042	76303065	7	+	28162770	OCIAML5	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.39750070739851573	[53]	[73]	-3	hSpCas9	negative selection	11187987
76303796	76303819	7	+	28162770	OCIAML5	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.3495672903056537	[24]	[114]	9	hSpCas9	negative selection	11187988
76302818	76302841	7	-	28162770	OCIAML5	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.017401865993777355	[288]	[527]	0	hSpCas9	negative selection	11187989
76302833	76302856	7	+	28162770	OCIAML5	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.3902942667050468	[122]	[290]	3	hSpCas9	negative selection	11187990
76302941	76302964	7	+	28162770	OCIAML5	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.23404858692459585	[251]	[534]	2	hSpCas9	negative selection	11187991
76302991	76303014	7	-	28162770	OCIAML5	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.46986152402336523	[205]	[514]	4	hSpCas9	negative selection	11187992
76302891	76302914	7	-	28162770	EOL1	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.07545222842946542	[125]	[62]	0	hSpCas9	negative selection	11357349
76303018	76303041	7	-	28162770	EOL1	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	1.0431922680691539	[34]	[37]	8	hSpCas9	negative selection	11357350
76303009	76303032	7	+	28162770	EOL1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	-0.33065420951601476	[844]	[353]	-2	hSpCas9	negative selection	11357351
76302790	76302813	7	-	28162770	EOL1	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.7357861281153667	[105]	[92]	6	hSpCas9	negative selection	11357352
76303042	76303065	7	+	28162770	EOL1	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.3261892754598752	[256]	[107]	-2	hSpCas9	negative selection	11357353
76303796	76303819	7	+	28162770	EOL1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.7238504213334056	[76]	[66]	6	hSpCas9	negative selection	11357354
76302818	76302841	7	-	28162770	EOL1	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	-0.11945941066855814	[465]	[225]	-1	hSpCas9	negative selection	11357355
76302833	76302856	7	+	28162770	EOL1	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.9443562526507148	[216]	[219]	7	hSpCas9	negative selection	11357356
76302941	76302964	7	+	28162770	EOL1	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.7887339162248148	[511]	[465]	7	hSpCas9	negative selection	11357357
76302991	76303014	7	-	28162770	EOL1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.1447732889333722	[404]	[192]	-1	hSpCas9	negative selection	11357358
76302891	76302914	7	-	28162770	MOLM13	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	0.5702510991742566	[67]	[72]	4	hSpCas9	negative selection	11526715
76303018	76303041	7	-	28162770	MOLM13	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.7165351895928485	[49]	[21]	-4	hSpCas9	negative selection	11526716
76303009	76303032	7	+	28162770	MOLM13	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.34215946586160606	[658]	[603]	2	hSpCas9	negative selection	11526717
76302790	76302813	7	-	28162770	MOLM13	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.9121914753286176	[60]	[82]	7	hSpCas9	negative selection	11526718
76303042	76303065	7	+	28162770	MOLM13	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	1.6044282144923445	[135]	[298]	9	hSpCas9	negative selection	11526719
76303796	76303819	7	+	28162770	MOLM13	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-0.6696141422053561	[54]	[24]	-4	hSpCas9	negative selection	11526720
76302818	76302841	7	-	28162770	MOLM13	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.5990069337867163	[493]	[540]	4	hSpCas9	negative selection	11526721
76302833	76302856	7	+	28162770	MOLM13	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	-0.01649616442499999	[276]	[197]	0	hSpCas9	negative selection	11526722
76302941	76302964	7	+	28162770	MOLM13	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.5878175573990618	[472]	[513]	4	hSpCas9	negative selection	11526723
76302991	76303014	7	-	28162770	MOLM13	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.1948708871381628	[463]	[383]	1	hSpCas9	negative selection	11526724
76302891	76302914	7	-	28162770	HEL	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	0.9413971475648721	[99]	[122]	7	hSpCas9	negative selection	11696081
76303018	76303041	7	-	28162770	HEL	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	1.7847578368727848	[28]	[63]	9	hSpCas9	negative selection	11696082
76303009	76303032	7	+	28162770	HEL	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.6655387013734946	[564]	[573]	6	hSpCas9	negative selection	11696083
76302790	76302813	7	-	28162770	HEL	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.586079858495524	[74]	[31]	-4	hSpCas9	negative selection	11696084
76303042	76303065	7	+	28162770	HEL	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	0.5547911327246545	[185]	[174]	5	hSpCas9	negative selection	11696085
76303796	76303819	7	+	28162770	HEL	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	1.606212955975243	[59]	[116]	9	hSpCas9	negative selection	11696086
76302818	76302841	7	-	28162770	HEL	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.3178186274178304	[361]	[288]	2	hSpCas9	negative selection	11696087
76302833	76302856	7	+	28162770	HEL	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.5625684833163734	[221]	[209]	5	hSpCas9	negative selection	11696088
76302941	76302964	7	+	28162770	HEL	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.38924519337616925	[421]	[353]	3	hSpCas9	negative selection	11696089
76302991	76303014	7	-	28162770	HEL	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.3109704144854416	[330]	[262]	2	hSpCas9	negative selection	11696090
76302891	76302914	7	-	28162770	MV411	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	1.186037006118632	[71]	[137]	9	hSpCas9	negative selection	11865447
76303018	76303041	7	-	28162770	MV411	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-2.074490544104587	[39]	[7]	-8	hSpCas9	negative selection	11865448
76303009	76303032	7	+	28162770	MV411	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.3798221039076968	[384]	[421]	3	hSpCas9	negative selection	11865449
76302790	76302813	7	-	28162770	MV411	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.44598323016485564	[60]	[69]	4	hSpCas9	negative selection	11865450
76303042	76303065	7	+	28162770	MV411	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	0.5922660477802165	[99]	[126]	5	hSpCas9	negative selection	11865451
76303796	76303819	7	+	28162770	MV411	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.4555457461129755	[57]	[66]	4	hSpCas9	negative selection	11865452
76302818	76302841	7	-	28162770	MV411	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.3280030320864439	[295]	[312]	3	hSpCas9	negative selection	11865453
76302833	76302856	7	+	28162770	MV411	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.5995437943351626	[122]	[156]	5	hSpCas9	negative selection	11865454
76302941	76302964	7	+	28162770	MV411	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.20334496659960466	[298]	[289]	1	hSpCas9	negative selection	11865455
76302991	76303014	7	-	28162770	MV411	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.4958905456069703	[302]	[180]	-4	hSpCas9	negative selection	11865456
76302891	76302914	7	-	28162770	MONOMAC1	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	-0.6995371875887371	[50]	[35]	-5	hSpCas9	negative selection	12034813
76303018	76303041	7	-	28162770	MONOMAC1	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-1.8850928407448135	[28]	[8]	-8	hSpCas9	negative selection	12034814
76303009	76303032	7	+	28162770	MONOMAC1	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.4753069705968924	[346]	[552]	5	hSpCas9	negative selection	12034815
76302790	76302813	7	-	28162770	MONOMAC1	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	-0.8027579079475071	[34]	[22]	-6	hSpCas9	negative selection	12034816
76303042	76303065	7	+	28162770	MONOMAC1	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.8719414730935084	[90]	[56]	-6	hSpCas9	negative selection	12034817
76303796	76303819	7	+	28162770	MONOMAC1	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.15443552344182376	[28]	[36]	1	hSpCas9	negative selection	12034818
76302818	76302841	7	-	28162770	MONOMAC1	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.9601771026332048	[151]	[338]	8	hSpCas9	negative selection	12034819
76302833	76302856	7	+	28162770	MONOMAC1	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	0.10657936955086697	[110]	[136]	1	hSpCas9	negative selection	12034820
76302941	76302964	7	+	28162770	MONOMAC1	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	0.1248912478278088	[203]	[254]	1	hSpCas9	negative selection	12034821
76302991	76303014	7	-	28162770	MONOMAC1	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.20281424840461415	[190]	[251]	2	hSpCas9	negative selection	12034822
76302891	76302914	7	-	28162770	OCIAML2	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	1.3586398732438831	[13]	[198]	9	hSpCas9	negative selection	12204179
76303018	76303041	7	-	28162770	OCIAML2	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-0.5775450291586735	[6]	[25]	-4	hSpCas9	negative selection	12204180
76303009	76303032	7	+	28162770	OCIAML2	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.055580088194905786	[70]	[408]	0	hSpCas9	negative selection	12204181
76302790	76302813	7	-	28162770	OCIAML2	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.851298269645201	[7]	[79]	7	hSpCas9	negative selection	12204182
76303042	76303065	7	+	28162770	OCIAML2	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	-0.4475462121291198	[30]	[125]	-4	hSpCas9	negative selection	12204183
76303796	76303819	7	+	28162770	OCIAML2	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	0.6527525902631208	[6]	[60]	6	hSpCas9	negative selection	12204184
76302818	76302841	7	-	28162770	OCIAML2	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.13602774657831407	[54]	[334]	1	hSpCas9	negative selection	12204185
76302833	76302856	7	+	28162770	OCIAML2	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	-0.13720609151696944	[24]	[125]	-1	hSpCas9	negative selection	12204186
76302941	76302964	7	+	28162770	OCIAML2	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.14870173035479872	[75]	[379]	-1	hSpCas9	negative selection	12204187
76302991	76303014	7	-	28162770	OCIAML2	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	-0.30333507984452074	[60]	[273]	-2	hSpCas9	negative selection	12204188
76302891	76302914	7	-	28162770	OCIAML3	viability	TGCGGGGCTCTCGATGGCGGCGG	HSPB1	ENSG00000106211	0.4059923596758368	[14]	[59]	4	hSpCas9	negative selection	12373545
76303018	76303041	7	-	28162770	OCIAML3	viability	TCAGCTCGTCCGGGGCGAAGTGG	HSPB1	ENSG00000106211	-1.3045010231291778	[8]	[10]	-7	hSpCas9	negative selection	12373546
76303009	76303032	7	+	28162770	OCIAML3	viability	GGATGTCAACCACTTCGCCCCGG	HSPB1	ENSG00000106211	0.4327096980516161	[106]	[435]	4	hSpCas9	negative selection	12373547
76302790	76302813	7	-	28162770	OCIAML3	viability	CGAAGGCCTGGTCGAAGAGGCGG	HSPB1	ENSG00000106211	0.5865646053176576	[14]	[67]	5	hSpCas9	negative selection	12373548
76303042	76303065	7	+	28162770	OCIAML3	viability	GGTCAAGACCAAGGATGGCGTGG	HSPB1	ENSG00000106211	0.43658067950926	[34]	[142]	4	hSpCas9	negative selection	12373549
76303796	76303819	7	+	28162770	OCIAML3	viability	CCAAAGGCAAGCACGAGGAGCGG	HSPB1	ENSG00000106211	-1.5160051283228901	[17]	[18]	-8	hSpCas9	negative selection	12373550
76302818	76302841	7	-	28162770	OCIAML3	viability	GACCACTCCTCCGGCAGCCGGGG	HSPB1	ENSG00000106211	0.6586577921260854	[63]	[304]	6	hSpCas9	negative selection	12373551
76302833	76302856	7	+	28162770	OCIAML3	viability	GAGTGGTCGCAGTGGTTAGGCGG	HSPB1	ENSG00000106211	-0.41712987824008385	[45]	[103]	-3	hSpCas9	negative selection	12373552
76302941	76302964	7	+	28162770	OCIAML3	viability	CTCAGCCGGCAACTCAGCAGCGG	HSPB1	ENSG00000106211	-0.08680029711745241	[107]	[306]	0	hSpCas9	negative selection	12373553
76302991	76303014	7	-	28162770	OCIAML3	viability	CATCCAGGGACACGCGCCAGCGG	HSPB1	ENSG00000106211	0.36018867006271194	[79]	[309]	3	hSpCas9	negative selection	12373554