Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8988
• Symbol: HSPB3
• Description: heat shock protein family B (small) member 3

DataSource: http://genomecrispr.dkfz.de/#!/results/HSPB3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
54455967	54455990	5	+	26472758	Jiyoye	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.2309368257340474	[234]	[150]	-2	hSpCas9	negative selection	75010
54455995	54456018	5	-	26472758	Jiyoye	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	-0.7663074393496282	[405]	[179]	-5	hSpCas9	negative selection	75011
54455911	54455934	5	-	26472758	Jiyoye	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.6665620103245229	[65]	[78]	5	hSpCas9	negative selection	75012
54456029	54456052	5	-	26472758	Jiyoye	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.24158931578789855	[82]	[73]	1	hSpCas9	negative selection	75013
54456140	54456163	5	+	26472758	Jiyoye	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.2418004470413626	[276]	[246]	1	hSpCas9	negative selection	75014
54455897	54455920	5	+	26472758	Jiyoye	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	-0.11095561073707383	[231]	[161]	-1	hSpCas9	negative selection	75015
54455945	54455968	5	+	26472758	Jiyoye	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-0.03838406254986637	[206]	[151]	0	hSpCas9	negative selection	75016
54455976	54455999	5	-	26472758	Jiyoye	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	1.8701473578484193	[36]	[101]	8	hSpCas9	negative selection	75017
54455838	54455861	5	+	26472758	Jiyoye	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	-0.337567563252052	[123]	[73]	-2	hSpCas9	negative selection	75018
54455858	54455881	5	+	26472758	Jiyoye	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	1.6295678028423217	[14]	[34]	8	hSpCas9	negative selection	75019
54455967	54455990	5	+	26472758	KBM7	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.5253835190711685	[743,396]	[247,121]	-4	hSpCas9	negative selection	266128
54455995	54456018	5	-	26472758	KBM7	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.22815097005739204	[1374,1290]	[775,698]	2	hSpCas9	negative selection	266129
54455911	54455934	5	-	26472758	KBM7	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.35548560720357014	[227,221]	[157,115]	4	hSpCas9	negative selection	266130
54456029	54456052	5	-	26472758	KBM7	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.5063788675427323	[356,204]	[156,206]	5	hSpCas9	negative selection	266131
54456140	54456163	5	+	26472758	KBM7	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.7369862048747706	[1221,1011]	[980,772]	7	hSpCas9	negative selection	266132
54455897	54455920	5	+	26472758	KBM7	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.10296755429813376	[738,497]	[361,258]	1	hSpCas9	negative selection	266133
54455945	54455968	5	+	26472758	KBM7	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.6136821734062797	[994,714]	[544,663]	6	hSpCas9	negative selection	266134
54455976	54455999	5	-	26472758	KBM7	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.33260435506100305	[549,328]	[267,242]	3	hSpCas9	negative selection	266135
54455838	54455861	5	+	26472758	KBM7	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.05909624165867555	[254,194]	[113,104]	0	hSpCas9	negative selection	266136
54455858	54455881	5	+	26472758	KBM7	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.8038379923392012	[140,144]	[181,60]	8	hSpCas9	negative selection	266137
54455967	54455990	5	+	26472758	Raji	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.23800353233775176	[309]	[60]	-2	hSpCas9	negative selection	457246
54455995	54456018	5	-	26472758	Raji	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.16844868655933132	[716]	[186]	1	hSpCas9	negative selection	457247
54455911	54455934	5	-	26472758	Raji	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	1.0555446038539813	[84]	[40]	8	hSpCas9	negative selection	457248
54456029	54456052	5	-	26472758	Raji	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.3020074007641024	[169]	[31]	-3	hSpCas9	negative selection	457249
54456140	54456163	5	+	26472758	Raji	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	1.0462432405596955	[481]	[230]	8	hSpCas9	negative selection	457250
54455897	54455920	5	+	26472758	Raji	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.4650878595864918	[230]	[73]	4	hSpCas9	negative selection	457251
54455945	54455968	5	+	26472758	Raji	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.23969082747772985	[353]	[96]	2	hSpCas9	negative selection	457252
54455976	54455999	5	-	26472758	Raji	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.22564641699341928	[198]	[53]	2	hSpCas9	negative selection	457253
54455838	54455861	5	+	26472758	Raji	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.43278382216776684	[165]	[51]	4	hSpCas9	negative selection	457254
54455858	54455881	5	+	26472758	Raji	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.7854554404862369	[69]	[27]	7	hSpCas9	negative selection	457255
54455967	54455990	5	+	26472758	K562	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.6743574770595804	[517]	[273]	-4	hSpCas9	negative selection	648364
54455995	54456018	5	-	26472758	K562	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.17149613302952704	[1196]	[1137]	1	hSpCas9	negative selection	648365
54455911	54455934	5	-	26472758	K562	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.47512641721489834	[172]	[202]	4	hSpCas9	negative selection	648366
54456029	54456052	5	-	26472758	K562	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.0878783406044607	[383]	[304]	0	hSpCas9	negative selection	648367
54456140	54456163	5	+	26472758	K562	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.5847588596676894	[980]	[1241]	5	hSpCas9	negative selection	648368
54455897	54455920	5	+	26472758	K562	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.7317931690925006	[422]	[592]	6	hSpCas9	negative selection	648369
54455945	54455968	5	+	26472758	K562	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.2599436511720219	[646]	[653]	2	hSpCas9	negative selection	648370
54455976	54455999	5	-	26472758	K562	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	1.2253099047187423	[303]	[599]	9	hSpCas9	negative selection	648371
54455838	54455861	5	+	26472758	K562	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.8950292706231164	[178]	[280]	7	hSpCas9	negative selection	648372
54455858	54455881	5	+	26472758	K562	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.054343382641872884	[138]	[112]	0	hSpCas9	negative selection	648373
54455999	54456022	5	+	26627737	DLD1	viability	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.5322077485414203	[1103]	[498,561,446]	5	hSpCas9	negative selection	828992
54456008	54456031	5	-	26627737	DLD1	viability	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.7963756041371146	[227]	[152,104,113]	7	hSpCas9	negative selection	828993
54456023	54456046	5	-	26627737	DLD1	viability	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.5246770644364951	[533]	[209,452,89]	5	hSpCas9	negative selection	828994
54456029	54456052	5	-	26627737	DLD1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.2626378714973088	[197]	[60,21,128]	2	hSpCas9	negative selection	828995
54456046	54456069	5	+	26627737	DLD1	viability	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.7573235292182869	[386]	[284,57,255]	7	hSpCas9	negative selection	828996
54455999	54456022	5	+	26627737	GBM cells	viability after 5 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.014843986687268718	[489]	[246,283]	0	hSpCas9	negative selection	911307
54456008	54456031	5	-	26627737	GBM cells	viability after 5 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.2308956344369707	[142]	[89,89]	3	hSpCas9	negative selection	911308
54456023	54456046	5	-	26627737	GBM cells	viability after 5 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	-0.35018133999023426	[308]	[128,130]	-5	hSpCas9	negative selection	911309
54456029	54456052	5	-	26627737	GBM cells	viability after 5 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.15553390913669085	[134]	[77,51]	-2	hSpCas9	negative selection	911310
54456046	54456069	5	+	26627737	GBM cells	viability after 5 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.01962202448541806	[240]	[126,127]	0	hSpCas9	negative selection	911311
54455999	54456022	5	+	26627737	GBM cells	viability after 13 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.08302144625562757	[489]	[333,238]	1	hSpCas9	negative selection	993622
54456008	54456031	5	-	26627737	GBM cells	viability after 13 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.17792162996461214	[142]	[116,63]	2	hSpCas9	negative selection	993623
54456023	54456046	5	-	26627737	GBM cells	viability after 13 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.004976686089485538	[308]	[229,117]	0	hSpCas9	negative selection	993624
54456029	54456052	5	-	26627737	GBM cells	viability after 13 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.12774592652695582	[134]	[68,88]	1	hSpCas9	negative selection	993625
54456046	54456069	5	+	26627737	GBM cells	viability after 13 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.4224770262820439	[240]	[128,71]	-5	hSpCas9	negative selection	993626
54455999	54456022	5	+	26627737	GBM cells	viability after 21 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.6204143824156434	[489]	[426,392]	6	hSpCas9	negative selection	1075937
54456008	54456031	5	-	26627737	GBM cells	viability after 21 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-1.3457507091761955	[142]	[28,31]	-8	hSpCas9	negative selection	1075938
54456023	54456046	5	-	26627737	GBM cells	viability after 21 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	-0.1380388195839279	[308]	[162,142]	-1	hSpCas9	negative selection	1075939
54456029	54456052	5	-	26627737	GBM cells	viability after 21 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.2167601793728027	[134]	[41,21]	-7	hSpCas9	negative selection	1075940
54456046	54456069	5	+	26627737	GBM cells	viability after 21 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.38575736768580343	[240]	[106,93]	-4	hSpCas9	negative selection	1075941
54455999	54456022	5	+	26627737	RPE1	viability after 9 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.37274066100273484	[2432]	[925,1063]	2	hSpCas9	negative selection	1158252
54456008	54456031	5	-	26627737	RPE1	viability after 9 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.11834049345058248	[950]	[382,133]	-1	hSpCas9	negative selection	1158253
54456023	54456046	5	-	26627737	RPE1	viability after 9 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.3897114776153228	[995]	[449,354]	2	hSpCas9	negative selection	1158254
54456029	54456052	5	-	26627737	RPE1	viability after 9 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.9421326486107016	[112]	[45,251]	8	hSpCas9	negative selection	1158255
54456046	54456069	5	+	26627737	RPE1	viability after 9 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.4126397737456836	[1197]	[193,394]	-3	hSpCas9	negative selection	1158256
54455999	54456022	5	+	26627737	RPE1	viability after 12 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.07654911171990952	[2432]	[749,624]	0	hSpCas9	negative selection	1240567
54456008	54456031	5	-	26627737	RPE1	viability after 12 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.392398644704348	[950]	[250,134]	-3	hSpCas9	negative selection	1240568
54456023	54456046	5	-	26627737	RPE1	viability after 12 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.4278480717844361	[995]	[392,324]	3	hSpCas9	negative selection	1240569
54456029	54456052	5	-	26627737	RPE1	viability after 12 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	2.0603915983621723	[112]	[28,229]	9	hSpCas9	negative selection	1240570
54456046	54456069	5	+	26627737	RPE1	viability after 12 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.08128894214872262	[1197]	[192,421]	0	hSpCas9	negative selection	1240571
54455999	54456022	5	+	26627737	RPE1	viability after 15 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.3252758528096724	[2432]	[1210,525]	2	hSpCas9	negative selection	1322882
54456008	54456031	5	-	26627737	RPE1	viability after 15 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.5030204408527377	[950]	[283,98]	-3	hSpCas9	negative selection	1322883
54456023	54456046	5	-	26627737	RPE1	viability after 15 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.334819030205941	[995]	[335,373]	2	hSpCas9	negative selection	1322884
54456029	54456052	5	-	26627737	RPE1	viability after 15 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.7395245713381289	[112]	[36,173]	8	hSpCas9	negative selection	1322885
54456046	54456069	5	+	26627737	RPE1	viability after 15 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.3769824444573001	[1197]	[206,312]	-2	hSpCas9	negative selection	1322886
54455999	54456022	5	+	26627737	RPE1	viability after 18 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4548908602278481	[2432]	[1146,635]	3	hSpCas9	negative selection	1405197
54456008	54456031	5	-	26627737	RPE1	viability after 18 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.35105162605539164	[950]	[221,178]	-2	hSpCas9	negative selection	1405198
54456023	54456046	5	-	26627737	RPE1	viability after 18 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	-0.1149798763378101	[995]	[253,241]	0	hSpCas9	negative selection	1405199
54456029	54456052	5	-	26627737	RPE1	viability after 18 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	2.370454438607925	[112]	[104,213]	9	hSpCas9	negative selection	1405200
54456046	54456069	5	+	26627737	RPE1	viability after 18 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.5139050666574887	[1197]	[223,228]	-3	hSpCas9	negative selection	1405201
54455999	54456022	5	+	26627737	HeLa	viability after 8 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	-0.10086255295735591	[848]	[321,324,378]	-1	hSpCas9	negative selection	1487512
54456008	54456031	5	-	26627737	HeLa	viability after 8 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.7723780080429046	[148]	[223,108,29]	6	hSpCas9	negative selection	1487513
54456023	54456046	5	-	26627737	HeLa	viability after 8 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.21981285509965065	[568]	[247,213,386]	2	hSpCas9	negative selection	1487514
54456029	54456052	5	-	26627737	HeLa	viability after 8 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.295633167815598	[290]	[70,50,37]	-8	hSpCas9	negative selection	1487515
54456046	54456069	5	+	26627737	HeLa	viability after 8 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.3669110592264929	[369]	[270,234,135]	3	hSpCas9	negative selection	1487516
54455999	54456022	5	+	26627737	HeLa	viability after 12 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4976488057795505	[848]	[731,306,473]	4	hSpCas9	negative selection	1569827
54456008	54456031	5	-	26627737	HeLa	viability after 12 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	1.4370655212019787	[148]	[97,177,220]	8	hSpCas9	negative selection	1569828
54456023	54456046	5	-	26627737	HeLa	viability after 12 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	-0.04508671943210263	[568]	[210,116,366]	0	hSpCas9	negative selection	1569829
54456029	54456052	5	-	26627737	HeLa	viability after 12 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.18996238839946378	[290]	[249,78,91]	1	hSpCas9	negative selection	1569830
54456046	54456069	5	+	26627737	HeLa	viability after 12 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.10147118352440267	[369]	[69,127,228]	-1	hSpCas9	negative selection	1569831
54455999	54456022	5	+	26627737	HeLa	viability after 15 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.6126998128898908	[848]	[639,464,474]	5	hSpCas9	negative selection	1652142
54456008	54456031	5	-	26627737	HeLa	viability after 15 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.8269075237517552	[148]	[69,124,129]	6	hSpCas9	negative selection	1652143
54456023	54456046	5	-	26627737	HeLa	viability after 15 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.2251906980696623	[568]	[285,123,412]	2	hSpCas9	negative selection	1652144
54456029	54456052	5	-	26627737	HeLa	viability after 15 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.2621748756781788	[290]	[43,93,6]	-8	hSpCas9	negative selection	1652145
54456046	54456069	5	+	26627737	HeLa	viability after 15 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.2253850157025063	[369]	[231,65,233]	2	hSpCas9	negative selection	1652146
54455999	54456022	5	+	26627737	HeLa	viability after 18 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.6148806153513082	[848]	[430,384,474]	5	hSpCas9	negative selection	1734457
54456008	54456031	5	-	26627737	HeLa	viability after 18 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.8435589608855247	[148]	[44,108,129]	6	hSpCas9	negative selection	1734458
54456023	54456046	5	-	26627737	HeLa	viability after 18 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.2650725770340828	[568]	[203,105,412]	2	hSpCas9	negative selection	1734459
54456029	54456052	5	-	26627737	HeLa	viability after 18 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.244119524160153	[290]	[28,79,6]	-8	hSpCas9	negative selection	1734460
54456046	54456069	5	+	26627737	HeLa	viability after 18 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.27105059086750166	[369]	[167,52,233]	2	hSpCas9	negative selection	1734461
54455999	54456022	5	+	26627737	HCT116	viability after 6 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	-0.6762544388009339	[1370]	[72,168]	-4	hSpCas9	negative selection	1816772
54456008	54456031	5	-	26627737	HCT116	viability after 6 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.4858595341660348	[254]	[7,39]	-3	hSpCas9	negative selection	1816773
54456023	54456046	5	-	26627737	HCT116	viability after 6 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.019205460476606283	[615]	[208,36]	0	hSpCas9	negative selection	1816774
54456029	54456052	5	-	26627737	HCT116	viability after 6 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.7093874257050452	[306]	[56,90]	4	hSpCas9	negative selection	1816775
54456046	54456069	5	+	26627737	HCT116	viability after 6 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.6178239490221332	[409]	[105,94]	3	hSpCas9	negative selection	1816776
54455999	54456022	5	+	26627737	HCT116	viability after 8 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.20398849685571108	[709]	[440,478,431]	2	hSpCas9	negative selection	1899087
54456008	54456031	5	-	26627737	HCT116	viability after 8 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.705158505237542	[184]	[178,168,150]	6	hSpCas9	negative selection	1899088
54456023	54456046	5	-	26627737	HCT116	viability after 8 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.8818801624329947	[301]	[330,331,257]	7	hSpCas9	negative selection	1899089
54456029	54456052	5	-	26627737	HCT116	viability after 8 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.6836359517371775	[78]	[107,78,23]	6	hSpCas9	negative selection	1899090
54456046	54456069	5	+	26627737	HCT116	viability after 8 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.46225968777848997	[415]	[181,197,119]	-5	hSpCas9	negative selection	1899091
54455999	54456022	5	+	26627737	HCT116	viability after 9 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.12239656175282065	[1370]	[512,307]	0	hSpCas9	negative selection	1981402
54456008	54456031	5	-	26627737	HCT116	viability after 9 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.5331165034832381	[254]	[98,5]	-4	hSpCas9	negative selection	1981403
54456023	54456046	5	-	26627737	HCT116	viability after 9 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	-0.10059122090983137	[615]	[201,114]	0	hSpCas9	negative selection	1981404
54456029	54456052	5	-	26627737	HCT116	viability after 9 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.27041241894326584	[306]	[204,14]	2	hSpCas9	negative selection	1981405
54456046	54456069	5	+	26627737	HCT116	viability after 9 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	1.4188019687147624	[409]	[161,395]	8	hSpCas9	negative selection	1981406
54455999	54456022	5	+	26627737	HCT116	viability after 12 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4673117414659811	[709]	[557,438,544]	4	hSpCas9	negative selection	2063717
54456008	54456031	5	-	26627737	HCT116	viability after 12 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.3612662014104195	[184]	[122,131,119]	3	hSpCas9	negative selection	2063718
54456023	54456046	5	-	26627737	HCT116	viability after 12 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.7091179111005719	[301]	[251,216,308]	6	hSpCas9	negative selection	2063719
54456029	54456052	5	-	26627737	HCT116	viability after 12 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.8280393079781829	[78]	[79,91,48]	7	hSpCas9	negative selection	2063720
54456046	54456069	5	+	26627737	HCT116	viability after 12 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.7508930048763637	[415]	[115,172,102]	-7	hSpCas9	negative selection	2063721
54455999	54456022	5	+	26627737	HCT116	viability after 15 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.05736885063615227	[709]	[459,457,359]	0	hSpCas9	negative selection	2146032
54456008	54456031	5	-	26627737	HCT116	viability after 15 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.17109518150625713	[184]	[139,155,65]	1	hSpCas9	negative selection	2146033
54456023	54456046	5	-	26627737	HCT116	viability after 15 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.5759866982650071	[301]	[373,266,149]	5	hSpCas9	negative selection	2146034
54456029	54456052	5	-	26627737	HCT116	viability after 15 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.6588640293194474	[78]	[142,163,122]	9	hSpCas9	negative selection	2146035
54456046	54456069	5	+	26627737	HCT116	viability after 15 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.35699316402228415	[415]	[139,314,99]	-4	hSpCas9	negative selection	2146036
54455999	54456022	5	+	26627737	HCT116	viability after 18 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	-0.0026108907553918925	[709]	[335,352,337]	0	hSpCas9	negative selection	2228347
54456008	54456031	5	-	26627737	HCT116	viability after 18 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.6809318794200505	[184]	[60,169,199]	5	hSpCas9	negative selection	2228348
54456023	54456046	5	-	26627737	HCT116	viability after 18 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.017457978155386	[301]	[317,197,380]	7	hSpCas9	negative selection	2228349
54456029	54456052	5	-	26627737	HCT116	viability after 18 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.2216093604927263	[78]	[96,78,91]	8	hSpCas9	negative selection	2228350
54456046	54456069	5	+	26627737	HCT116	viability after 18 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.3941448672763316	[415]	[193,179,79]	-4	hSpCas9	negative selection	2228351
54455813	54455836	5	-	24336569	HL60	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.15701513363607345	[1371]	[2603]	-1	hSpCas9	negative selection	2270960
54455819	54455842	5	+	24336569	HL60	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.26828193839822817	[338]	[863]	2	hSpCas9	negative selection	2270961
54455826	54455849	5	-	24336569	HL60	viability	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	0.275811679086299	[636]	[1631]	2	hSpCas9	negative selection	2270962
54455837	54455860	5	-	24336569	HL60	viability	CTCGAGCTTCAAACTCTTCCTGG	HSPB3	ENSG00000169271	0.8440421731469693	[153]	[584]	7	hSpCas9	negative selection	2270963
54455883	54455906	5	+	24336569	HL60	viability	CATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	-0.25544972333969207	[844]	[1497]	-2	hSpCas9	negative selection	2270964
54455897	54455920	5	+	24336569	HL60	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	-0.9192434092158565	[604]	[676]	-7	hSpCas9	negative selection	2270965
54455905	54455928	5	+	24336569	HL60	viability	GGCCAACCATCGTGGACCTGAGG	HSPB3	ENSG00000169271	-1.214626754540817	[895]	[816]	-8	hSpCas9	negative selection	2270966
54455932	54455955	5	-	24336569	HL60	viability	TGGAGGAGACTGCGCTGCCCTGG	HSPB3	ENSG00000169271	-0.27291834479266996	[345]	[605]	-2	hSpCas9	negative selection	2270967
54455945	54455968	5	+	24336569	HL60	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.06191911336092422	[511]	[1130]	0	hSpCas9	negative selection	2270968
54455952	54455975	5	-	24336569	HL60	viability	GTCTCTGCCGCTGAGTCCACTGG	HSPB3	ENSG00000169271	0.06614001309000861	[426]	[945]	0	hSpCas9	negative selection	2270969
54455813	54455836	5	-	24336569	KBM7	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.4010768403432987	[850]	[3064]	4	hSpCas9	negative selection	2338137
54455819	54455842	5	+	24336569	KBM7	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.7648704215399869	[207]	[963]	7	hSpCas9	negative selection	2338138
54455826	54455849	5	-	24336569	KBM7	viability	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	0.14445287749706365	[474]	[1431]	1	hSpCas9	negative selection	2338139
54455837	54455860	5	-	24336569	KBM7	viability	CTCGAGCTTCAAACTCTTCCTGG	HSPB3	ENSG00000169271	-0.3652596585745028	[280]	[594]	-3	hSpCas9	negative selection	2338140
54455883	54455906	5	+	24336569	KBM7	viability	CATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.6145169245430298	[539]	[2254]	5	hSpCas9	negative selection	2338141
54455897	54455920	5	+	24336569	KBM7	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.5473319267783179	[283]	[1131]	5	hSpCas9	negative selection	2338142
54455905	54455928	5	+	24336569	KBM7	viability	GGCCAACCATCGTGGACCTGAGG	HSPB3	ENSG00000169271	0.7054154089435526	[399]	[1778]	6	hSpCas9	negative selection	2338143
54455932	54455955	5	-	24336569	KBM7	viability	TGGAGGAGACTGCGCTGCCCTGG	HSPB3	ENSG00000169271	0.09372207537613397	[245]	[715]	0	hSpCas9	negative selection	2338144
54455945	54455968	5	+	24336569	KBM7	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.1580146369444043	[323]	[985]	1	hSpCas9	negative selection	2338145
54455952	54455975	5	-	24336569	KBM7	viability	GTCTCTGCCGCTGAGTCCACTGG	HSPB3	ENSG00000169271	0.008324569395017134	[334]	[918]	0	hSpCas9	negative selection	2338146
54455813	54455836	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.4774871267953227	[3,3]	[0,3]	-6	hSpCas9	positive selection	2994402
54455916	54455939	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.1202024728918133	[4,4]	[4,4]	2	hSpCas9	positive selection	2994403
54456008	54456031	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.3363022042747381	[3,3]	[3,4]	7	hSpCas9	positive selection	2994404
54455946	54455969	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-0.1256973197861573	[3,2]	[4,0]	-2	hSpCas9	positive selection	2994405
54455813	54455836	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.3783056866964278	[3,3]	[3,3]	6	hSpCas9	positive selection	3062260
54455916	54455939	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-0.174348023913852	[4,4]	[4,1]	-3	hSpCas9	positive selection	3062261
54456008	54456031	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.28169039526993583	[3,3]	[3,2]	5	hSpCas9	positive selection	3062262
54455946	54455969	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.10268137282665266	[3,3]	[3,1]	1	hSpCas9	positive selection	3062263
54456042	54456065		+	24336571	A375	resistance to PLX after 7 days	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.05969273931357255	[5,5]	[5,6]	2	hSpCas9	positive selection	3120000
54456225	54456248		-	24336571	A375	resistance to PLX after 7 days	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.210852463599992	[14,21]	[21,21]	6	hSpCas9	positive selection	3120001
54455914	54455937		+	24336571	A375	resistance to PLX after 7 days	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.02991448686696642	[12,13]	[11,14]	1	hSpCas9	positive selection	3120002
54456042	54456065		+	24336571	A375	resistance to PLX after 14 days	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.5299372499398518	[2,4]	[2,1]	5	hSpCas9	positive selection	3177793
54456225	54456248		-	24336571	A375	resistance to PLX after 14 days	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.8636066197016148	[14,20]	[15,13]	7	hSpCas9	positive selection	3177794
54455914	54455937		+	24336571	A375	resistance to PLX after 14 days	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	1.24546105530921	[15,13]	[13,19]	8	hSpCas9	positive selection	3177795
54456042	54456065		+	24336571	A375	viability after 7 days	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-1.325207240391458	[16]	[5,5]	-9	hSpCas9	negative selection	3235586
54456225	54456248		-	24336571	A375	viability after 7 days	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.061533757471489536	[18]	[14,21]	0	hSpCas9	negative selection	3235587
54455914	54455937		+	24336571	A375	viability after 7 days	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.33107747964144485	[10]	[12,13]	5	hSpCas9	negative selection	3235588
54456042	54456065		+	24336571	A375	viability after 14 days	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-1.8186784471332607	[16]	[2,4]	-9	hSpCas9	negative selection	3293379
54456225	54456248		-	24336571	A375	viability after 14 days	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.011865246935042484	[18]	[14,20]	0	hSpCas9	negative selection	3293380
54455914	54455937		+	24336571	A375	viability after 14 days	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.5167468656515055	[10]	[15,13]	6	hSpCas9	negative selection	3293381
54455819	54455842	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.9714924790500457	[299,299]	[0,0]	-6	hSpCas9	positive selection	3373463
54456094	54456117	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	-0.8873320313860472	[282,282]	[0,0]	-6	hSpCas9	positive selection	3373464
54455914	54455937	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	1.5849008694743394	[50,50]	[0,0]	6	hSpCas9	positive selection	3373465
54455813	54455836	5	-	26780180	HT29	viability (Avana library 4 designs)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	1.96742736646475	[]	[]	7	hSpCas9	negative selection	3431730
54455915	54455938	5	+	26780180	HT29	viability (Avana library 4 designs)	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.361861237714228	[]	[]	1	hSpCas9	negative selection	3431731
54456008	54456031	5	-	26780180	HT29	viability (Avana library 4 designs)	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	1.01714751118528	[]	[]	4	hSpCas9	negative selection	3431732
54455945	54455968	5	+	26780180	HT29	viability (Avana library 4 designs)	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.119321461930916	[]	[]	0	hSpCas9	negative selection	3431733
54455915	54455938	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-1.33869975905546	[]	[]	-2	hSpCas9	negative selection	3517528
54455945	54455968	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	2.15934162077496	[]	[]	3	hSpCas9	negative selection	3517529
54456008	54456031	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	6.21399539213582	[]	[]	9	hSpCas9	negative selection	3517530
54455813	54455836	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	2.59069454180893	[]	[]	4	hSpCas9	negative selection	3517531
54455826	54455849	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	-5.49540669623641	[]	[]	-5	hSpCas9	negative selection	3517532
54455858	54455881	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	2.76732097729552	[]	[]	4	hSpCas9	negative selection	3517533
54455915	54455938	5	+	26780180	A375	viability (Avana lentiGuide)	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-0.248674972960768	[]	[]	0	hSpCas9	negative selection	3626187
54455945	54455968	5	+	26780180	A375	viability (Avana lentiGuide)	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-2.78588208137934	[]	[]	-5	hSpCas9	negative selection	3626188
54456008	54456031	5	-	26780180	A375	viability (Avana lentiGuide)	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.698704643861638	[]	[]	0	hSpCas9	negative selection	3626189
54455813	54455836	5	-	26780180	A375	viability (Avana lentiGuide)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-4.25030373736512	[]	[]	-7	hSpCas9	negative selection	3626190
54455826	54455849	5	-	26780180	A375	viability (Avana lentiGuide)	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	1.908508459656	[]	[]	2	hSpCas9	negative selection	3626191
54455858	54455881	5	+	26780180	A375	viability (Avana lentiGuide)	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.537384668626305	[]	[]	0	hSpCas9	negative selection	3626192
54455915	54455938	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.02091210918916256	[5]	[6,4]	0	hSpCas9	positive selection	3734846
54455945	54455968	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-0.11597633072036316	[4]	[4,3]	-2	hSpCas9	positive selection	3734847
54456008	54456031	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.11727209097973831	[4]	[6,3]	3	hSpCas9	positive selection	3734848
54455813	54455836	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.2662962678645568	[5]	[5,6]	7	hSpCas9	positive selection	3734849
54455826	54455849	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	-0.1446766335797362	[6]	[5,4]	-2	hSpCas9	positive selection	3734850
54455858	54455881	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.03895589956820758	[4]	[5,3]	1	hSpCas9	positive selection	3734851
54455915	54455938	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.21855095943381206	[6]	[6,5]	5	hSpCas9	positive selection	3843453
54455945	54455968	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-0.42729147784500743	[4]	[3,1]	-5	hSpCas9	positive selection	3843454
54456008	54456031	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.5280897159349567	[5]	[1,3]	-6	hSpCas9	positive selection	3843455
54455813	54455836	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.3100648092521392	[5]	[5,5]	8	hSpCas9	positive selection	3843456
54455826	54455849	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTCTTCCTGGTAACGCACTGG	HSPB3	ENSG00000169271	0.1549792269550605	[7]	[6,6]	3	hSpCas9	positive selection	3843457
54455858	54455881	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.05657475882885264	[5]	[3,4]	-1	hSpCas9	positive selection	3843458
54456094	54456117	5	-	26780180	A375	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.734119878438786	[]	[]	2	hSpCas9	negative selection	3949457
54455813	54455836	5	-	26780180	A375	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.840101847168429	[]	[]	3	hSpCas9	negative selection	3949458
54455819	54455842	5	+	26780180	A375	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	1.83373380969113	[]	[]	9	hSpCas9	negative selection	3949459
54456042	54456065	5	+	26780180	A375	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	1.41879634109904	[]	[]	7	hSpCas9	negative selection	3949460
54456225	54456248	5	-	26780180	A375	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.426270778415973	[]	[]	1	hSpCas9	negative selection	3949461
54455914	54455937	5	+	26780180	A375	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.372795900282801	[]	[]	0	hSpCas9	negative selection	3949462
54456094	54456117	5	-	26780180	HT29	viability (GeCKOv2 library)	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.188186354882424	[]	[]	0	hSpCas9	negative selection	4057423
54455813	54455836	5	-	26780180	HT29	viability (GeCKOv2 library)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.583638306005731	[]	[]	2	hSpCas9	negative selection	4057424
54455819	54455842	5	+	26780180	HT29	viability (GeCKOv2 library)	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	2.73651536266933	[]	[]	9	hSpCas9	negative selection	4057425
54456042	54456065	5	+	26780180	HT29	viability (GeCKOv2 library)	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.330915458785688	[]	[]	0	hSpCas9	negative selection	4057426
54456225	54456248	5	-	26780180	HT29	viability (GeCKOv2 library)	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.28913005249708	[]	[]	0	hSpCas9	negative selection	4057427
54455914	54455937	5	+	26780180	HT29	viability (GeCKOv2 library)	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	1.29695558451131	[]	[]	6	hSpCas9	negative selection	4057428
54456042	54456065	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.317860789641017	[3]	[1,1]	-7	hSpCas9	positive selection	4143583
54456225	54456248	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.010981423704650994	[4]	[1,3]	0	hSpCas9	positive selection	4143584
54455914	54455937	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.26427674377061955	[3]	[1,4]	6	hSpCas9	positive selection	4143585
54456042	54456065	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.22300448468535752	[3]	[0,3,2,0]	1	hSpCas9	positive selection	4207605
54456225	54456248	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.22601279915253636	[3]	[1,0,4,0]	1	hSpCas9	positive selection	4207606
54455914	54455937	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.32305046532353193	[2]	[1,0,4,0]	2	hSpCas9	positive selection	4207607
54456042	54456065	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.01599243255282007	[3]	[3,1]	0	hSpCas9	positive selection	4275989
54455813	54455836	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.15914225370169954	[3]	[3,2]	3	hSpCas9	positive selection	4275990
54456225	54456248	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.4132128778747902	[4]	[3,4]	8	hSpCas9	positive selection	4275991
54455819	54455842	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.406090621234769	[3]	[2,1]	-7	hSpCas9	positive selection	4340249
54456094	54456117	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.05356818032071797	[3]	[3,1]	1	hSpCas9	positive selection	4340250
54455914	54455937	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.04297687402806716	[1]	[1,0]	-1	hSpCas9	positive selection	4340251
54455884	54455906	5	+	27760321	OCIAML3	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.2834507462702105	[444,373]	[330,462]	3	hSpCas9	negative selection	4408304
54455916	54455938	5	+	27760321	OCIAML3	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.9674219018603891	[200,178]	[234,361]	9	hSpCas9	negative selection	4408305
54455976	54455998	5	-	27760321	OCIAML3	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.039700954491144635	[676,594]	[330,680]	0	hSpCas9	negative selection	4408306
54456008	54456030	5	-	27760321	OCIAML3	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.12446291753857205	[547,476]	[381,346]	-1	hSpCas9	negative selection	4408307
54456047	54456069	5	+	27760321	OCIAML3	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.559426959199342	[713,554]	[779,655]	6	hSpCas9	negative selection	4408308
54455884	54455906	5	+	27760321	OCIAML2	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.36490880649239654	[444,373]	[386,474]	5	hSpCas9	negative selection	4491767
54455916	54455938	5	+	27760321	OCIAML2	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-0.13730916393615034	[200,178]	[101,188]	-2	hSpCas9	negative selection	4491768
54455976	54455998	5	-	27760321	OCIAML2	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.3391320849827985	[676,594]	[398,414]	-4	hSpCas9	negative selection	4491769
54456008	54456030	5	-	27760321	OCIAML2	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.3715460058539782	[547,476]	[459,633]	5	hSpCas9	negative selection	4491770
54456047	54456069	5	+	27760321	OCIAML2	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.16087019601687924	[713,554]	[533,616]	2	hSpCas9	negative selection	4491771
54455884	54455906	5	+	27760321	MV411	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	-1.0935897795554772	[444,373]	[56,229]	-6	hSpCas9	negative selection	4575230
54455916	54455938	5	+	27760321	MV411	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-0.053590105047904624	[200,178]	[158,62]	0	hSpCas9	negative selection	4575231
54455976	54455998	5	-	27760321	MV411	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.33477551930102967	[676,594]	[226,489]	-2	hSpCas9	negative selection	4575232
54456008	54456030	5	-	27760321	MV411	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.43949820157594943	[547,476]	[231,273]	-3	hSpCas9	negative selection	4575233
54456047	54456069	5	+	27760321	MV411	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.5469775628634072	[713,554]	[258,322]	-4	hSpCas9	negative selection	4575234
54455884	54455906	5	+	27760321	HL60	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	1.1795930704343354	[444,373]	[764,743]	9	hSpCas9	negative selection	4658693
54455916	54455938	5	+	27760321	HL60	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.6977551440866676	[200,178]	[213,290]	7	hSpCas9	negative selection	4658694
54455976	54455998	5	-	27760321	HL60	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.6334170960405079	[676,594]	[863,740]	7	hSpCas9	negative selection	4658695
54456008	54456030	5	-	27760321	HL60	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.13977965234825834	[547,476]	[447,472]	1	hSpCas9	negative selection	4658696
54456047	54456069	5	+	27760321	HL60	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.13985393123595735	[713,554]	[585,546]	1	hSpCas9	negative selection	4658697
54455884	54455906	5	+	27760321	HT1080	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.10098242075446662	[373,291]	[105,181]	0	hSpCas9	negative selection	4742156
54455916	54455938	5	+	27760321	HT1080	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	-0.8587797583676571	[178,139]	[56,10]	-4	hSpCas9	negative selection	4742157
54455976	54455998	5	-	27760321	HT1080	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	1.0240370982631655	[594,463]	[374,487]	5	hSpCas9	negative selection	4742158
54456008	54456030	5	-	27760321	HT1080	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.553713150834915	[476,371]	[129,98]	-2	hSpCas9	negative selection	4742159
54456047	54456069	5	+	27760321	HT1080	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	1.316099669551698	[554,432]	[668,293]	7	hSpCas9	negative selection	4742160
54455884	54455906	5	+	27760321	HT29	viability after 7 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.09082637174126747	[373,291]	[485,475,410]	1	hSpCas9	negative selection	4825619
54455916	54455938	5	+	27760321	HT29	viability after 7 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	1.259960316353483	[178,139]	[511,541,423]	9	hSpCas9	negative selection	4825620
54455976	54455998	5	-	27760321	HT29	viability after 7 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.013112369066643925	[594,463]	[695,703,661]	0	hSpCas9	negative selection	4825621
54456008	54456030	5	-	27760321	HT29	viability after 7 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.14511732346730963	[476,371]	[531,680,586]	2	hSpCas9	negative selection	4825622
54456047	54456069	5	+	27760321	HT29	viability after 7 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.2631702099911742	[554,432]	[641,945,682]	4	hSpCas9	negative selection	4825623
54455884	54455906	5	+	27760321	HT29	viability after 25 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.14624893180228193	[373,291]	[204,464,627]	1	hSpCas9	negative selection	4909082
54455916	54455938	5	+	27760321	HT29	viability after 25 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.14378811897573884	[178,139]	[164,189,256]	1	hSpCas9	negative selection	4909083
54455976	54455998	5	-	27760321	HT29	viability after 25 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.026185835070498098	[594,463]	[769,562,491]	0	hSpCas9	negative selection	4909084
54456008	54456030	5	-	27760321	HT29	viability after 25 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.05240510251824096	[476,371]	[376,664,470]	0	hSpCas9	negative selection	4909085
54456047	54456069	5	+	27760321	HT29	viability after 25 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.05415542858350436	[554,432]	[659,496,596]	0	hSpCas9	negative selection	4909086
54455884	54455906	5	+	27760321	HT29	viability after 22 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.38783793643801556	[373,291]	[326,568,620]	4	hSpCas9	negative selection	4992545
54455916	54455938	5	+	27760321	HT29	viability after 22 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.8432724653183645	[178,139]	[279,376,336]	8	hSpCas9	negative selection	4992546
54455976	54455998	5	-	27760321	HT29	viability after 22 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.13883998230285155	[594,463]	[699,605,355]	-1	hSpCas9	negative selection	4992547
54456008	54456030	5	-	27760321	HT29	viability after 22 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.06097859072060893	[476,371]	[376,747,286]	0	hSpCas9	negative selection	4992548
54456047	54456069	5	+	27760321	HT29	viability after 22 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.1682465135280422	[554,432]	[407,540,578]	-2	hSpCas9	negative selection	4992549
54455884	54455906	5	+	27760321	HT29	viability after 19 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	-0.002033550385566657	[373,291]	[432,514,204]	0	hSpCas9	negative selection	5076008
54455916	54455938	5	+	27760321	HT29	viability after 19 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.6769979559192607	[178,139]	[132,399,323]	7	hSpCas9	negative selection	5076009
54455976	54455998	5	-	27760321	HT29	viability after 19 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.4745733198466803	[594,463]	[1115,878,567]	5	hSpCas9	negative selection	5076010
54456008	54456030	5	-	27760321	HT29	viability after 19 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.3230944771390418	[476,371]	[487,952,376]	3	hSpCas9	negative selection	5076011
54456047	54456069	5	+	27760321	HT29	viability after 19 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.08941239856494804	[554,432]	[544,567,482]	-1	hSpCas9	negative selection	5076012
54455884	54455906	5	+	27760321	HT29	viability after 16 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.10943786538559509	[373,291]	[501,408,303]	1	hSpCas9	negative selection	5159471
54455916	54455938	5	+	27760321	HT29	viability after 16 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	1.259998939814824	[178,139]	[225,396,640]	9	hSpCas9	negative selection	5159472
54455976	54455998	5	-	27760321	HT29	viability after 16 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.09320479652743119	[594,463]	[785,656,241]	-1	hSpCas9	negative selection	5159473
54456008	54456030	5	-	27760321	HT29	viability after 16 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.21368725359707727	[476,371]	[567,616,466]	2	hSpCas9	negative selection	5159474
54456047	54456069	5	+	27760321	HT29	viability after 16 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.3550870584988775	[554,432]	[722,711,686]	4	hSpCas9	negative selection	5159475
54455884	54455906	5	+	27760321	HT29	viability after 13 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	-0.04173645508743985	[373,291]	[219,441,458]	0	hSpCas9	negative selection	5242934
54455916	54455938	5	+	27760321	HT29	viability after 13 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.5684573689611154	[178,139]	[281,330,213]	7	hSpCas9	negative selection	5242935
54455976	54455998	5	-	27760321	HT29	viability after 13 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.5477940008095885	[594,463]	[492,341,424]	-6	hSpCas9	negative selection	5242936
54456008	54456030	5	-	27760321	HT29	viability after 13 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.20972762919508917	[476,371]	[464,449,365]	-2	hSpCas9	negative selection	5242937
54456047	54456069	5	+	27760321	HT29	viability after 13 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.05961940177572772	[554,432]	[585,539,524]	0	hSpCas9	negative selection	5242938
54455884	54455906	5	+	27760321	HT29	viability after 10 days	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	-0.5252336521144683	[373,291]	[261,407,201]	-6	hSpCas9	negative selection	5326397
54455916	54455938	5	+	27760321	HT29	viability after 10 days	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.3988356028265747	[178,139]	[342,331,117]	5	hSpCas9	negative selection	5326398
54455976	54455998	5	-	27760321	HT29	viability after 10 days	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.2552954644112865	[594,463]	[593,485,578]	-3	hSpCas9	negative selection	5326399
54456008	54456030	5	-	27760321	HT29	viability after 10 days	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	-0.06708605448180038	[476,371]	[377,830,321]	-1	hSpCas9	negative selection	5326400
54456047	54456069	5	+	27760321	HT29	viability after 10 days	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.009337874994824413	[554,432]	[826,563,472]	0	hSpCas9	negative selection	5326401
54455884	54455906	5	+	27760321	MOLM13	viability	ATGCTTTATATGCACTGCCTGG	HSPB3	ENSG00000169271	0.24428392965434342	[444,373]	[418,147]	1	hSpCas9	negative selection	5409860
54455916	54455938	5	+	27760321	MOLM13	viability	GTGGACCTGAGGAAAACCAGGG	HSPB3	ENSG00000169271	0.10688661009612566	[200,178]	[77,146]	0	hSpCas9	negative selection	5409861
54455976	54455998	5	-	27760321	MOLM13	viability	GGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	1.0373050506553323	[676,594]	[815,665]	7	hSpCas9	negative selection	5409862
54456008	54456030	5	-	27760321	MOLM13	viability	GAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.8232346907441257	[547,476]	[901,176]	6	hSpCas9	negative selection	5409863
54456047	54456069	5	+	27760321	MOLM13	viability	CATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.762715593042044	[713,554]	[168,243]	-5	hSpCas9	negative selection	5409864
54455737	54455760	5	+	27661255	K562	viability	GGCAGTGGAAGGTTGGCAGAAGG	HSPB3	ENSG00000169271	0.2538779320366751	[415,512]	[497,391]	8	dCas9-KRAB	negative selection	5485775
54455945	54455968	5	+	27661255	K562	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.03234030610755481	[706,680]	[704,449]	1	dCas9-KRAB	negative selection	5485776
54456140	54456163	5	+	27661255	K562	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	-0.060361810748587486	[386,338]	[288,269]	-2	dCas9-KRAB	negative selection	5485777
54456042	54456065	5	+	27260156	BXPC3	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.027811704747575383	[657]	[702,579,635,791]	0	hSpCas9	negative selection	5548449
54455813	54455836	5	-	27260156	BXPC3	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.2814574636441597	[804]	[944,832,1306,1024]	6	hSpCas9	negative selection	5548450
54456225	54456248	5	-	27260156	BXPC3	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.12646644240668325	[1009]	[1200,1183,939,1282]	3	hSpCas9	negative selection	5548451
54455819	54455842	5	+	27260156	BXPC3	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.1587582287592163	[820]	[685,787,807,800]	-4	hSpCas9	negative selection	5612709
54456094	54456117	5	-	27260156	BXPC3	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.22266844591485913	[719]	[702,801,940,1115]	5	hSpCas9	negative selection	5612710
54455914	54455937	5	+	27260156	BXPC3	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.23618147305233927	[157]	[175,124,94,162]	-5	hSpCas9	negative selection	5612711
54456042	54456065	5	+	27260156	A673	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.18881946791878101	[657]	[963,917,824,900]	4	hSpCas9	negative selection	5669700
54455813	54455836	5	-	27260156	A673	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.04390742676173909	[804]	[914,958,910,961]	-1	hSpCas9	negative selection	5669701
54456225	54456248	5	-	27260156	A673	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.09087618773925699	[1009]	[1508,1114,1344,1219]	2	hSpCas9	negative selection	5669702
54455819	54455842	5	+	27260156	A673	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.266752173620214	[820]	[874,771,810,825]	-6	hSpCas9	negative selection	5733960
54456094	54456117	5	-	27260156	A673	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.23842194305800002	[719]	[1047,921,882,1243]	5	hSpCas9	negative selection	5733961
54455914	54455937	5	+	27260156	A673	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.07344000515465132	[157]	[235,180,140,247]	1	hSpCas9	negative selection	5733962
54456042	54456065	5	+	27260156	A375	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.03831308115173715	[657]	[864,691,939,514]	0	hSpCas9	negative selection	5790951
54455813	54455836	5	-	27260156	A375	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.29803290368691016	[804]	[893,1155,1295,1258]	4	hSpCas9	negative selection	5790952
54456225	54456248	5	-	27260156	A375	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.2582089192511101	[1009]	[1323,1685,1553,1143]	4	hSpCas9	negative selection	5790953
54455819	54455842	5	+	27260156	A375	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.09717981326604808	[820]	[1024,1096,1211,801]	1	hSpCas9	negative selection	5855211
54456094	54456117	5	-	27260156	A375	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.28454137053586637	[719]	[974,1082,1027,1015]	4	hSpCas9	negative selection	5855212
54455914	54455937	5	+	27260156	A375	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.2227371265328253	[157]	[224,248,246,151]	3	hSpCas9	negative selection	5855213
54456042	54456065	5	+	27260156	COLO741	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.10936043164276177	[657]	[1117,721,896]	2	hSpCas9	negative selection	5912202
54455813	54455836	5	-	27260156	COLO741	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.027116207122316216	[804]	[1111,1012,1023]	0	hSpCas9	negative selection	5912203
54456225	54456248	5	-	27260156	COLO741	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.08010277688674416	[1009]	[1508,1361,1239]	1	hSpCas9	negative selection	5912204
54455819	54455842	5	+	27260156	COLO741	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.09847655908015329	[820]	[1293,1173,927]	2	hSpCas9	negative selection	5976462
54456094	54456117	5	-	27260156	COLO741	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.30543442010614863	[719]	[1349,1040,1041]	6	hSpCas9	negative selection	5976463
54455914	54455937	5	+	27260156	COLO741	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.4840666545030754	[157]	[160,113,157]	-8	hSpCas9	negative selection	5976464
54456042	54456065	5	+	27260156	CAL120	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.056786569004603216	[657]	[791,694,1054]	0	hSpCas9	negative selection	6033453
54455813	54455836	5	-	27260156	CAL120	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.3589190630769069	[804]	[1508,1301,1079]	5	hSpCas9	negative selection	6033454
54456225	54456248	5	-	27260156	CAL120	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.37201613601080474	[1009]	[2075,1323,1547]	5	hSpCas9	negative selection	6033455
54455819	54455842	5	+	27260156	CAL120	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.16944918902537076	[820]	[1487,891,1117]	2	hSpCas9	negative selection	6097713
54456094	54456117	5	-	27260156	CAL120	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.5387682499039959	[719]	[2261,891,901]	7	hSpCas9	negative selection	6097714
54455914	54455937	5	+	27260156	CAL120	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.15263817884769604	[157]	[129,132,258]	-2	hSpCas9	negative selection	6097715
54456042	54456065	5	+	27260156	CADOES1	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.05367525253285538	[657]	[522,496,632,709]	-1	hSpCas9	negative selection	6154704
54455813	54455836	5	-	27260156	CADOES1	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.18444468338282138	[804]	[956,950,623,871]	3	hSpCas9	negative selection	6154705
54456225	54456248	5	-	27260156	CADOES1	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.2741239553685102	[1009]	[1210,1186,1000,1144]	4	hSpCas9	negative selection	6154706
54455819	54455842	5	+	27260156	CADOES1	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.16588962505670402	[820]	[580,745,687,708]	-3	hSpCas9	negative selection	6218964
54456094	54456117	5	-	27260156	CADOES1	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.4119849475364179	[719]	[840,946,1040,728]	6	hSpCas9	negative selection	6218965
54455914	54455937	5	+	27260156	CADOES1	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.3353292283969602	[157]	[109,74,133,147]	-5	hSpCas9	negative selection	6218966
54456042	54456065	5	+	27260156	EWS502	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.0050504222696828305	[657]	[621,987,678,487]	0	hSpCas9	negative selection	6275955
54455813	54455836	5	-	27260156	EWS502	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.054183875319782526	[804]	[914,904,865,843]	0	hSpCas9	negative selection	6275956
54456225	54456248	5	-	27260156	EWS502	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	-0.011992815725768713	[1009]	[1199,993,1002,1024]	0	hSpCas9	negative selection	6275957
54455819	54455842	5	+	27260156	EWS502	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.1299490286104089	[820]	[770,838,793,770]	-2	hSpCas9	negative selection	6340215
54456094	54456117	5	-	27260156	EWS502	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.25874200794969615	[719]	[814,921,878,1050]	4	hSpCas9	negative selection	6340216
54455914	54455937	5	+	27260156	EWS502	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.15417016694281416	[157]	[97,228,254,170]	2	hSpCas9	negative selection	6340217
54456042	54456065	5	+	27260156	EW8	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.06018772814718587	[657]	[679,522,375,686]	1	hSpCas9	negative selection	6397206
54455813	54455836	5	-	27260156	EW8	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.17351062061957923	[804]	[595,509,473,750]	-3	hSpCas9	negative selection	6397207
54456225	54456248	5	-	27260156	EW8	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.13248957714494813	[1009]	[1077,877,816,846]	2	hSpCas9	negative selection	6397208
54455819	54455842	5	+	27260156	EW8	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.25549314839092996	[820]	[793,564,476,431]	-5	hSpCas9	negative selection	6461466
54456094	54456117	5	-	27260156	EW8	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.2989711873086439	[719]	[1131,729,466,628]	5	hSpCas9	negative selection	6461467
54455914	54455937	5	+	27260156	EW8	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.3067929598723349	[157]	[155,130,173,168]	5	hSpCas9	negative selection	6461468
54456042	54456065	5	+	27260156	CORL105	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.012834010148491504	[657]	[760,737,692,902]	0	hSpCas9	negative selection	6518457
54455813	54455836	5	-	27260156	CORL105	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.12515908957276534	[804]	[995,775,1211,1158]	2	hSpCas9	negative selection	6518458
54456225	54456248	5	-	27260156	CORL105	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.17947540988341681	[1009]	[1135,1167,1854,1273]	3	hSpCas9	negative selection	6518459
54455819	54455842	5	+	27260156	CORL105	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.10235969689490731	[820]	[907,690,1241,798]	-2	hSpCas9	negative selection	6582717
54456094	54456117	5	-	27260156	CORL105	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.30336979677954967	[719]	[904,943,1211,1122]	5	hSpCas9	negative selection	6582718
54455914	54455937	5	+	27260156	CORL105	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.022148508731944405	[157]	[192,109,289,175]	0	hSpCas9	negative selection	6582719
54456042	54456065	5	+	27260156	HS294T	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.2523252197850532	[657]	[251,291,251,443]	3	hSpCas9	negative selection	6639708
54455813	54455836	5	-	27260156	HS294T	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.4296351461748763	[804]	[287,474,430,506]	6	hSpCas9	negative selection	6639709
54456225	54456248	5	-	27260156	HS294T	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.23604771330327967	[1009]	[347,598,478,409]	3	hSpCas9	negative selection	6639710
54455819	54455842	5	+	27260156	HS294T	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.19648255210340215	[820]	[225,217,228,473]	-3	hSpCas9	negative selection	6703968
54456094	54456117	5	-	27260156	HS294T	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.4960276459248665	[719]	[320,470,360,425]	6	hSpCas9	negative selection	6703969
54455914	54455937	5	+	27260156	HS294T	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.4063816950154957	[157]	[55,23,37,69]	-5	hSpCas9	negative selection	6703970
54456042	54456065	5	+	27260156	HCC44	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.20456271084224353	[657]	[915,672,917,954]	3	hSpCas9	negative selection	6760959
54455813	54455836	5	-	27260156	HCC44	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.14897987142017766	[804]	[833,982,1603,708]	2	hSpCas9	negative selection	6760960
54456225	54456248	5	-	27260156	HCC44	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.2403223347132457	[1009]	[1344,1036,1393,1651]	4	hSpCas9	negative selection	6760961
54455819	54455842	5	+	27260156	HCC44	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.06475425909974741	[820]	[971,812,1433,766]	1	hSpCas9	negative selection	6825219
54456094	54456117	5	-	27260156	HCC44	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.48821153782135274	[719]	[879,1263,1160,1213]	7	hSpCas9	negative selection	6825220
54455914	54455937	5	+	27260156	HCC44	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.1509661319058957	[157]	[179,110,280,101]	-2	hSpCas9	negative selection	6825221
54456042	54456065	5	+	27260156	G402	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.24129937492989306	[657]	[630,934,1276,904]	3	hSpCas9	negative selection	6882210
54455813	54455836	5	-	27260156	G402	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.22102781941882121	[804]	[1013,1124,1799,640]	2	hSpCas9	negative selection	6882211
54456225	54456248	5	-	27260156	G402	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	-0.015129307644096812	[1009]	[1288,1268,1164,1165]	0	hSpCas9	negative selection	6882212
54455819	54455842	5	+	27260156	G402	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.3071254150995653	[820]	[1134,712,767,667]	-4	hSpCas9	negative selection	6946470
54456094	54456117	5	-	27260156	G402	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.10142257811720745	[719]	[981,1199,871,742]	1	hSpCas9	negative selection	6946471
54455914	54455937	5	+	27260156	G402	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.20149081783500722	[157]	[160,234,173,105]	-3	hSpCas9	negative selection	6946472
54456042	54456065	5	+	27260156	L33	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.1091455862140217	[657]	[514,311,440,863]	2	hSpCas9	negative selection	7003461
54455813	54455836	5	-	27260156	L33	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.36679523963395855	[804]	[1064,485,608,931]	7	hSpCas9	negative selection	7003462
54456225	54456248	5	-	27260156	L33	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.19193683145037	[1009]	[1009,489,738,1235]	4	hSpCas9	negative selection	7003463
54455819	54455842	5	+	27260156	L33	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.31794916020487674	[820]	[654,237,503,597]	-6	hSpCas9	negative selection	7067721
54456094	54456117	5	-	27260156	L33	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.07166298150376194	[719]	[800,266,482,803]	1	hSpCas9	negative selection	7067722
54455914	54455937	5	+	27260156	L33	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.365163703161935	[157]	[150,61,154,265]	7	hSpCas9	negative selection	7067723
54456042	54456065	5	+	27260156	K562	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.15633658824984153	[657]	[861,703,588,484]	2	hSpCas9	negative selection	7124712
54455813	54455836	5	-	27260156	K562	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.256886657020042	[804]	[830,681,1316,599]	3	hSpCas9	negative selection	7124713
54456225	54456248	5	-	27260156	K562	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.3315031751503461	[1009]	[1414,608,1418,1066]	4	hSpCas9	negative selection	7124714
54455819	54455842	5	+	27260156	K562	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.20955194527108012	[820]	[755,925,823,855]	2	hSpCas9	negative selection	7188972
54456094	54456117	5	-	27260156	K562	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.48337841208762145	[719]	[1140,720,1169,584]	6	hSpCas9	negative selection	7188973
54455914	54455937	5	+	27260156	K562	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.5702308317949065	[157]	[270,40,10,68]	-6	hSpCas9	negative selection	7188974
54456042	54456065	5	+	27260156	HT29	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.23912688147593353	[657]	[1183,854,947,809]	4	hSpCas9	negative selection	7245963
54455813	54455836	5	-	27260156	HT29	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.026197678812884595	[804]	[1063,991,1104,716]	0	hSpCas9	negative selection	7245964
54456225	54456248	5	-	27260156	HT29	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.18939569806413759	[1009]	[1777,1200,1493,1158]	3	hSpCas9	negative selection	7245965
54455819	54455842	5	+	27260156	HT29	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.11864387846493363	[820]	[1188,953,820,750]	-2	hSpCas9	negative selection	7310223
54456094	54456117	5	-	27260156	HT29	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.4693356435907845	[719]	[1283,1185,1307,1079]	8	hSpCas9	negative selection	7310224
54455914	54455937	5	+	27260156	HT29	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.05530194801851285	[157]	[221,271,202,117]	1	hSpCas9	negative selection	7310225
54456042	54456065	5	+	27260156	MHHES1	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.1034392995097162	[657]	[1026,893,431,495]	-2	hSpCas9	negative selection	7367214
54455813	54455836	5	-	27260156	MHHES1	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.20342874228553842	[804]	[1058,1578,754,856]	4	hSpCas9	negative selection	7367215
54456225	54456248	5	-	27260156	MHHES1	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.052604192905627345	[1009]	[1438,1184,1015,1100]	1	hSpCas9	negative selection	7367216
54455819	54455842	5	+	27260156	MHHES1	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.12728311452008456	[820]	[950,826,981,661]	-2	hSpCas9	negative selection	7431474
54456094	54456117	5	-	27260156	MHHES1	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.22353778345857522	[719]	[951,1368,897,657]	4	hSpCas9	negative selection	7431475
54455914	54455937	5	+	27260156	MHHES1	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.14271152746376115	[157]	[201,197,162,100]	-3	hSpCas9	negative selection	7431476
54456042	54456065	5	+	27260156	MEWO	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.06467024041236635	[657]	[732,766,447]	1	hSpCas9	negative selection	7488465
54455813	54455836	5	-	27260156	MEWO	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.08346724861981836	[804]	[944,645,831]	1	hSpCas9	negative selection	7488466
54456225	54456248	5	-	27260156	MEWO	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.26132543515189544	[1009]	[1181,1337,885]	5	hSpCas9	negative selection	7488467
54455819	54455842	5	+	27260156	MEWO	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.15534418247404314	[820]	[962,455,703]	-3	hSpCas9	negative selection	7552725
54456094	54456117	5	-	27260156	MEWO	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.16974062945011736	[719]	[906,732,661]	4	hSpCas9	negative selection	7552726
54455914	54455937	5	+	27260156	MEWO	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.3559361270181105	[157]	[96,92,152]	-6	hSpCas9	negative selection	7552727
54456042	54456065	5	+	27260156	LNCAPCLONEFGC	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.0006994821092043968	[657]	[600,545,594,645]	0	hSpCas9	negative selection	7609716
54455813	54455836	5	-	27260156	LNCAPCLONEFGC	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.2968102175392441	[804]	[995,684,1080,859]	5	hSpCas9	negative selection	7609717
54456225	54456248	5	-	27260156	LNCAPCLONEFGC	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.1736737771110186	[1009]	[1124,947,1288,806]	2	hSpCas9	negative selection	7609718
54455819	54455842	5	+	27260156	LNCAPCLONEFGC	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.008622135511470619	[820]	[777,612,892,737]	0	hSpCas9	negative selection	7673976
54456094	54456117	5	-	27260156	LNCAPCLONEFGC	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.3848142650123514	[719]	[802,763,1029,841]	6	hSpCas9	negative selection	7673977
54455914	54455937	5	+	27260156	LNCAPCLONEFGC	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.24169483370683786	[157]	[179,141,233,131]	4	hSpCas9	negative selection	7673978
54456042	54456065	5	+	27260156	PANC0327	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.2546056749388088	[657]	[955,759,526,558]	4	hSpCas9	negative selection	7730967
54455813	54455836	5	-	27260156	PANC0327	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.34266724283880856	[804]	[794,952,1003,859]	5	hSpCas9	negative selection	7730968
54456225	54456248	5	-	27260156	PANC0327	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.2871760667396459	[1009]	[1206,985,1056,1151]	4	hSpCas9	negative selection	7730969
54455819	54455842	5	+	27260156	PANC0327	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.20297954124338813	[820]	[724,914,1045,652]	3	hSpCas9	negative selection	7795227
54456094	54456117	5	-	27260156	PANC0327	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.27929375180779004	[719]	[743,662,597,1110]	4	hSpCas9	negative selection	7795228
54455914	54455937	5	+	27260156	PANC0327	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.018664726320044123	[157]	[176,152,71,167]	0	hSpCas9	negative selection	7795229
54456042	54456065	5	+	27260156	NCIH2009	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.2104232081445533	[657]	[1073,969,1148]	3	hSpCas9	negative selection	7852218
54455813	54455836	5	-	27260156	NCIH2009	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.3369765263114527	[804]	[1325,1297,1618]	4	hSpCas9	negative selection	7852219
54456225	54456248	5	-	27260156	NCIH2009	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.4138479280912952	[1009]	[2325,1980,1415]	6	hSpCas9	negative selection	7852220
54455819	54455842	5	+	27260156	NCIH2009	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.2045074601807887	[820]	[1233,876,922]	-3	hSpCas9	negative selection	7916478
54456094	54456117	5	-	27260156	NCIH2009	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.2568198210029946	[719]	[1516,1096,1053]	3	hSpCas9	negative selection	7916479
54455914	54455937	5	+	27260156	NCIH2009	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.25682361720677926	[157]	[137,372,252]	3	hSpCas9	negative selection	7916480
54456042	54456065	5	+	27260156	NCIH1373	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.27307554701920567	[657]	[611,417,507,247]	-3	hSpCas9	negative selection	7973469
54455813	54455836	5	-	27260156	NCIH1373	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.2549574867908967	[804]	[1236,1105,811,309]	2	hSpCas9	negative selection	7973470
54456225	54456248	5	-	27260156	NCIH1373	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.5896809192818098	[1009]	[2351,1117,1401,559]	6	hSpCas9	negative selection	7973471
54455819	54455842	5	+	27260156	NCIH1373	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.042137987038387226	[820]	[871,947,612,301]	0	hSpCas9	negative selection	8037729
54456094	54456117	5	-	27260156	NCIH1373	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.6789155747239166	[719]	[2164,938,1039,312]	6	hSpCas9	negative selection	8037730
54455914	54455937	5	+	27260156	NCIH1373	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.7829270653793408	[157]	[112,92,69,36]	-7	hSpCas9	negative selection	8037731
54456042	54456065	5	+	27260156	PATU8902	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.6069037253196717	[657]	[1374,1755,637,2082]	6	hSpCas9	negative selection	8094720
54455813	54455836	5	-	27260156	PATU8902	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.5673972293802952	[804]	[1943,1511,1306,1996]	6	hSpCas9	negative selection	8094721
54456225	54456248	5	-	27260156	PATU8902	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.23210002149454034	[1009]	[1771,1400,1947,1359]	2	hSpCas9	negative selection	8094722
54455819	54455842	5	+	27260156	PATU8902	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.27156631813975185	[820]	[1147,1245,1500,1613]	2	hSpCas9	negative selection	8158980
54456094	54456117	5	-	27260156	PATU8902	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.7875192843256342	[719]	[1731,1887,1040,2522]	8	hSpCas9	negative selection	8158981
54455914	54455937	5	+	27260156	PATU8902	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.10835622706231707	[157]	[94,241,150,360]	-1	hSpCas9	negative selection	8158982
54456042	54456065	5	+	27260156	PANC1	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.19749549874553674	[657]	[464,791,660,689]	3	hSpCas9	negative selection	8215971
54455813	54455836	5	-	27260156	PANC1	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.2564638084190082	[804]	[855,1015,677,783]	4	hSpCas9	negative selection	8215972
54456225	54456248	5	-	27260156	PANC1	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.3947829112085479	[1009]	[1249,1581,1003,843]	6	hSpCas9	negative selection	8215973
54455819	54455842	5	+	27260156	PANC1	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.07200408011358794	[820]	[639,1104,447,581]	-1	hSpCas9	negative selection	8280231
54456094	54456117	5	-	27260156	PANC1	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.33389487560952624	[719]	[923,1022,563,658]	5	hSpCas9	negative selection	8280232
54455914	54455937	5	+	27260156	PANC1	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.16366262632689255	[157]	[137,242,110,134]	2	hSpCas9	negative selection	8280233
54456042	54456065	5	+	27260156	PANC0813	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.1517918961710938	[657]	[826,848,852,898]	2	hSpCas9	negative selection	8337222
54455813	54455836	5	-	27260156	PANC0813	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.27967546811529986	[804]	[1178,1396,1039,984]	4	hSpCas9	negative selection	8337223
54456225	54456248	5	-	27260156	PANC0813	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.12857256617039114	[1009]	[1379,1403,1549,883]	2	hSpCas9	negative selection	8337224
54455819	54455842	5	+	27260156	PANC0813	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.1948830206906822	[820]	[919,864,603,977]	-3	hSpCas9	negative selection	8401482
54456094	54456117	5	-	27260156	PANC0813	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.08045412911718708	[719]	[980,751,923,924]	1	hSpCas9	negative selection	8401483
54455914	54455937	5	+	27260156	PANC0813	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.3410708554320392	[157]	[194,131,147,116]	-5	hSpCas9	negative selection	8401484
54456042	54456065	5	+	27260156	RDES	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.27490145819381784	[657]	[410,513,712,958]	-5	hSpCas9	negative selection	8458473
54455813	54455836	5	-	27260156	RDES	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.20793230063708468	[804]	[894,1036,1042,1351]	3	hSpCas9	negative selection	8458474
54456225	54456248	5	-	27260156	RDES	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.12524929439270638	[1009]	[887,1127,1695,1461]	2	hSpCas9	negative selection	8458475
54455819	54455842	5	+	27260156	RDES	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.008537298608967792	[820]	[779,938,1056,1050]	0	hSpCas9	negative selection	8522733
54456094	54456117	5	-	27260156	RDES	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.3548000306726542	[719]	[939,1133,1079,1066]	5	hSpCas9	negative selection	8522734
54455914	54455937	5	+	27260156	RDES	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.04369035275712707	[157]	[146,131,218,220]	0	hSpCas9	negative selection	8522735
54456042	54456065	5	+	27260156	PC3	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.14625093360837904	[657]	[420,763,1397,643]	3	hSpCas9	negative selection	8579724
54455813	54455836	5	-	27260156	PC3	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.11367077719124463	[804]	[505,840,1799,765]	2	hSpCas9	negative selection	8579725
54456225	54456248	5	-	27260156	PC3	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	-0.004011636604831059	[1009]	[593,859,2075,999]	0	hSpCas9	negative selection	8579726
54455819	54455842	5	+	27260156	PC3	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.03064940680361883	[820]	[643,656,1236,816]	0	hSpCas9	negative selection	8643984
54456094	54456117	5	-	27260156	PC3	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.16409006546047233	[719]	[513,746,1478,789]	3	hSpCas9	negative selection	8643985
54455914	54455937	5	+	27260156	PC3	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.4663899975437269	[157]	[236,276,163,118]	8	hSpCas9	negative selection	8643986
54456042	54456065	5	+	27260156	PATU8988T	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.33785531659350587	[657]	[568,814,860,983]	6	hSpCas9	negative selection	8700975
54455813	54455836	5	-	27260156	PATU8988T	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.19270829730082095	[804]	[643,969,1147,789]	3	hSpCas9	negative selection	8700976
54456225	54456248	5	-	27260156	PATU8988T	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.05705419581024196	[1009]	[734,1159,972,1223]	1	hSpCas9	negative selection	8700977
54455819	54455842	5	+	27260156	PATU8988T	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	0.12613560341034025	[820]	[950,923,821,763]	2	hSpCas9	negative selection	8765235
54456094	54456117	5	-	27260156	PATU8988T	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.044956486562124254	[719]	[682,704,548,953]	0	hSpCas9	negative selection	8765236
54455914	54455937	5	+	27260156	PATU8988T	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.012066634113923502	[157]	[165,174,20,255]	0	hSpCas9	negative selection	8765237
54456042	54456065	5	+	27260156	T47D	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.0660045307858852	[657]	[784,710,705,1023]	1	hSpCas9	negative selection	8822226
54455813	54455836	5	-	27260156	T47D	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.14006232505530636	[804]	[1092,1004,1035,1000]	3	hSpCas9	negative selection	8822227
54456225	54456248	5	-	27260156	T47D	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.12412065676683315	[1009]	[1271,1239,1270,1351]	2	hSpCas9	negative selection	8822228
54455819	54455842	5	+	27260156	T47D	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.1064375711930462	[820]	[767,859,935,993]	-2	hSpCas9	negative selection	8886486
54456094	54456117	5	-	27260156	T47D	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.3451805841384513	[719]	[1029,977,1034,1231]	7	hSpCas9	negative selection	8886487
54455914	54455937	5	+	27260156	T47D	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.054477599880246474	[157]	[221,170,144,171]	-1	hSpCas9	negative selection	8886488
54456042	54456065	5	+	27260156	SU8686	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.00892306561612699	[657]	[586,534,638,887]	0	hSpCas9	negative selection	8943477
54455813	54455836	5	-	27260156	SU8686	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.3058958078309356	[804]	[739,851,1180,1261]	5	hSpCas9	negative selection	8943478
54456225	54456248	5	-	27260156	SU8686	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.24673330173473484	[1009]	[1190,1001,1106,1518]	4	hSpCas9	negative selection	8943479
54455819	54455842	5	+	27260156	SU8686	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.13335675289284676	[820]	[531,621,917,972]	-2	hSpCas9	negative selection	9007737
54456094	54456117	5	-	27260156	SU8686	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.11606914465721452	[719]	[654,762,689,1035]	2	hSpCas9	negative selection	9007738
54455914	54455937	5	+	27260156	SU8686	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.5835979035650725	[157]	[119,54,106,146]	-7	hSpCas9	negative selection	9007739
54456042	54456065	5	+	27260156	SKES1	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.17358896518047073	[657]	[785,923,559,716]	4	hSpCas9	negative selection	9064728
54455813	54455836	5	-	27260156	SKES1	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.056208199693397076	[804]	[1190,860,606,738]	1	hSpCas9	negative selection	9064729
54456225	54456248	5	-	27260156	SKES1	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.17403716516043888	[1009]	[1383,1210,1112,898]	4	hSpCas9	negative selection	9064730
54455819	54455842	5	+	27260156	SKES1	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.08931216793709407	[820]	[889,789,653,758]	-2	hSpCas9	negative selection	9128988
54456094	54456117	5	-	27260156	SKES1	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.09152011316833708	[719]	[776,848,738,706]	2	hSpCas9	negative selection	9128989
54455914	54455937	5	+	27260156	SKES1	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.1903292897151545	[157]	[238,193,133,162]	4	hSpCas9	negative selection	9128990
54456042	54456065	5	+	27260156	TOV112D	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.20222472141259995	[657]	[702,1121,664,629]	4	hSpCas9	negative selection	9185979
54455813	54455836	5	-	27260156	TOV112D	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.043332348029983536	[804]	[627,981,1079,656]	0	hSpCas9	negative selection	9185980
54456225	54456248	5	-	27260156	TOV112D	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	0.08904732246823355	[1009]	[1108,992,1234,950]	1	hSpCas9	negative selection	9185981
54455819	54455842	5	+	27260156	TOV112D	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.04242592590087668	[820]	[652,1020,690,867]	-1	hSpCas9	negative selection	9250239
54456094	54456117	5	-	27260156	TOV112D	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.15261959540418268	[719]	[1065,939,622,636]	3	hSpCas9	negative selection	9250240
54455914	54455937	5	+	27260156	TOV112D	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.2912796798002999	[157]	[284,209,133,157]	5	hSpCas9	negative selection	9250241
54456042	54456065	5	+	27260156	TC71	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	0.202447666814921	[657]	[611,879,847,915]	5	hSpCas9	negative selection	9307230
54455813	54455836	5	-	27260156	TC71	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	-0.14010306411947693	[804]	[671,711,839,916]	-4	hSpCas9	negative selection	9307231
54456225	54456248	5	-	27260156	TC71	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	-0.03729057063499375	[1009]	[791,1182,996,1268]	-1	hSpCas9	negative selection	9307232
54455819	54455842	5	+	27260156	TC71	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.11482204948899921	[820]	[718,873,645,1032]	-3	hSpCas9	negative selection	9371490
54456094	54456117	5	-	27260156	TC71	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.2837270350029285	[719]	[850,935,1030,938]	7	hSpCas9	negative selection	9371491
54455914	54455937	5	+	27260156	TC71	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	-0.28868005650550654	[157]	[167,152,128,101]	-7	hSpCas9	negative selection	9371492
54456042	54456065	5	+	27260156	TC32	viability	ATCATCATTCAGACCTTCGAAGG	HSPB3	ENSG00000169271	-0.012119625081379926	[657]	[588,350,932,708]	0	hSpCas9	negative selection	9428481
54455813	54455836	5	-	27260156	TC32	viability	AACGCACTGGAATCTCTATGAGG	HSPB3	ENSG00000169271	0.0950531776393414	[804]	[873,678,898,782]	1	hSpCas9	negative selection	9428482
54456225	54456248	5	-	27260156	TC32	viability	CGATGTCACTTAGTCCCAACTGG	HSPB3	ENSG00000169271	-0.04998295568252553	[1009]	[816,633,1237,1111]	-1	hSpCas9	negative selection	9428483
54455819	54455842	5	+	27260156	TC32	viability	AGAGATTCCAGTGCGTTACCAGG	HSPB3	ENSG00000169271	-0.11259663504923711	[820]	[770,512,717,887]	-2	hSpCas9	negative selection	9492741
54456094	54456117	5	-	27260156	TC32	viability	AAAACCGTGCTCATCCATTCTGG	HSPB3	ENSG00000169271	0.41208919608201233	[719]	[692,736,1378,910]	7	hSpCas9	negative selection	9492742
54455914	54455937	5	+	27260156	TC32	viability	TCGTGGACCTGAGGAAAACCAGG	HSPB3	ENSG00000169271	0.2764510552232524	[157]	[128,200,132,237]	5	hSpCas9	negative selection	9492743
54455999	54456022	5	+	27869803	HPAFII	viability after 27 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.3516348270119811	[521]	[431,281,NaN]	3	hSpCas9	negative selection	9592096
54456008	54456031	5	-	27869803	HPAFII	viability after 27 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.34920776301489875	[138]	[85,98,NaN]	3	hSpCas9	negative selection	9592097
54456023	54456046	5	-	27869803	HPAFII	viability after 27 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.082348021465572	[345]	[598,206,NaN]	8	hSpCas9	negative selection	9592098
54456029	54456052	5	-	27869803	HPAFII	viability after 27 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-2.1389364758808904	[114]	[16,10,NaN]	-8	hSpCas9	negative selection	9592099
54456046	54456069	5	+	27869803	HPAFII	viability after 27 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.869503843141024	[340]	[350,307,NaN]	7	hSpCas9	negative selection	9592100
54455999	54456022	5	+	27869803	HPAFII	viability after 15 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4020341085305692	[521]	[1093,521,NaN]	4	hSpCas9	negative selection	9674545
54456008	54456031	5	-	27869803	HPAFII	viability after 15 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.9233092231200198	[138]	[360,234,NaN]	8	hSpCas9	negative selection	9674546
54456023	54456046	5	-	27869803	HPAFII	viability after 15 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.7504021071371015	[345]	[1079,342,NaN]	8	hSpCas9	negative selection	9674547
54456029	54456052	5	-	27869803	HPAFII	viability after 15 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.3253696418627559	[114]	[81,28,NaN]	-8	hSpCas9	negative selection	9674548
54456046	54456069	5	+	27869803	HPAFII	viability after 15 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.4699530763072787	[340]	[707,382,NaN]	5	hSpCas9	negative selection	9674549
54455999	54456022	5	+	27869803	ASPC1	viability after 36 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4806946469382891	[1300]	[330,729,762]	5	hSpCas9	negative selection	9756994
54456008	54456031	5	-	27869803	ASPC1	viability after 36 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.3859734593075317	[259]	[66,243,53]	4	hSpCas9	negative selection	9756995
54456023	54456046	5	-	27869803	ASPC1	viability after 36 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	0.6213780067997783	[805]	[687,155,468]	6	hSpCas9	negative selection	9756996
54456029	54456052	5	-	27869803	ASPC1	viability after 36 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.0060196400054011	[245]	[76,27,29]	-7	hSpCas9	negative selection	9756997
54456046	54456069	5	+	27869803	ASPC1	viability after 36 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	-0.5085415850205982	[721]	[156,246,133]	-5	hSpCas9	negative selection	9756998
54455999	54456022	5	+	27869803	PATU8988S	viability after 35 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	-0.21172694187424368	[1047]	[350,377,NaN]	-2	hSpCas9	negative selection	9839443
54456008	54456031	5	-	27869803	PATU8988S	viability after 35 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	1.225573224848939	[307]	[325,253,NaN]	9	hSpCas9	negative selection	9839444
54456023	54456046	5	-	27869803	PATU8988S	viability after 35 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.332033495418106	[717]	[735,719,NaN]	9	hSpCas9	negative selection	9839445
54456029	54456052	5	-	27869803	PATU8988S	viability after 35 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.08170823610180467	[290]	[136,110,NaN]	0	hSpCas9	negative selection	9839446
54456046	54456069	5	+	27869803	PATU8988S	viability after 35 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.6600218151123493	[656]	[464,370,NaN]	7	hSpCas9	negative selection	9839447
54455999	54456022	5	+	27869803	PATU8988S	viability after 31 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	-0.14583025414057693	[1047]	[316,454,NaN]	-2	hSpCas9	negative selection	9921892
54456008	54456031	5	-	27869803	PATU8988S	viability after 31 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	1.2075604721824635	[307]	[247,328,NaN]	9	hSpCas9	negative selection	9921893
54456023	54456046	5	-	27869803	PATU8988S	viability after 31 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.1679785958395372	[717]	[553,756,NaN]	9	hSpCas9	negative selection	9921894
54456029	54456052	5	-	27869803	PATU8988S	viability after 31 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.030606405557069394	[290]	[106,121,NaN]	0	hSpCas9	negative selection	9921895
54456046	54456069	5	+	27869803	PATU8988S	viability after 31 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.3533280095133672	[656]	[302,374,NaN]	4	hSpCas9	negative selection	9921896
54455999	54456022	5	+	27869803	HPAFII	viability after 35 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.7452295911937039	[521]	[370,523,NaN]	5	hSpCas9	negative selection	10004341
54456008	54456031	5	-	27869803	HPAFII	viability after 35 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.39097987370840903	[138]	[48,140,NaN]	2	hSpCas9	negative selection	10004342
54456023	54456046	5	-	27869803	HPAFII	viability after 35 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.512765532924068	[345]	[758,207,NaN]	8	hSpCas9	negative selection	10004343
54456029	54456052	5	-	27869803	HPAFII	viability after 35 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.832025830406874	[114]	[13,18,NaN]	-7	hSpCas9	negative selection	10004344
54456046	54456069	5	+	27869803	HPAFII	viability after 35 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	0.9999871319696769	[340]	[388,295,NaN]	6	hSpCas9	negative selection	10004345
54455999	54456022	5	+	27869803	HPAFII	viability after 31 days	CTTTCAGATCCTGCTGGACGTGG	HSPB3	ENSG00000169271	0.4716892059085527	[521]	[422,387,NaN]	3	hSpCas9	negative selection	10086790
54456008	54456031	5	-	27869803	HPAFII	viability after 31 days	GGAACTGGACCACGTCCAGCAGG	HSPB3	ENSG00000169271	0.41566231698362227	[138]	[82,126,NaN]	3	hSpCas9	negative selection	10086791
54456023	54456046	5	-	27869803	HPAFII	viability after 31 days	TGATGTCTTCAGGGAGGAACTGG	HSPB3	ENSG00000169271	1.2524089794754953	[345]	[654,252,NaN]	8	hSpCas9	negative selection	10086792
54456029	54456052	5	-	27869803	HPAFII	viability after 31 days	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-2.084764153100884	[114]	[19,9,NaN]	-8	hSpCas9	negative selection	10086793
54456046	54456069	5	+	27869803	HPAFII	viability after 31 days	TCATTCAGACCTTCGAAGGCTGG	HSPB3	ENSG00000169271	1.4023498481345718	[340]	[647,350,NaN]	8	hSpCas9	negative selection	10086794
54455967	54455990	5	+	28162770	P31FUJ	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.02385531414288239	[153]	[177]	0	hSpCas9	negative selection	10171804
54455995	54456018	5	-	28162770	P31FUJ	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	-0.03876200496215265	[645]	[738]	0	hSpCas9	negative selection	10171805
54455911	54455934	5	-	28162770	P31FUJ	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.3173948781461011	[111]	[163]	3	hSpCas9	negative selection	10171806
54456029	54456052	5	-	28162770	P31FUJ	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.1724295864348968	[116]	[121]	-2	hSpCas9	negative selection	10171807
54456140	54456163	5	+	28162770	P31FUJ	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.3224686113699725	[359]	[528]	3	hSpCas9	negative selection	10171808
54455897	54455920	5	+	28162770	P31FUJ	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.14376114704982945	[170]	[221]	1	hSpCas9	negative selection	10171809
54455945	54455968	5	+	28162770	P31FUJ	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.2311448953454116	[550]	[759]	2	hSpCas9	negative selection	10171810
54455976	54455999	5	-	28162770	P31FUJ	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.6000878097503631	[223]	[398]	6	hSpCas9	negative selection	10171811
54455838	54455861	5	+	28162770	P31FUJ	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.9895902169220693	[143]	[335]	9	hSpCas9	negative selection	10171812
54455858	54455881	5	+	28162770	P31FUJ	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.03849981740301578	[86]	[104]	0	hSpCas9	negative selection	10171813
54455967	54455990	5	+	28162770	TF1	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10341170
54455995	54456018	5	-	28162770	TF1	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	NaN	[NaN]	[668]	1	hSpCas9	negative selection	10341171
54455911	54455934	5	-	28162770	TF1	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10341172
54456029	54456052	5	-	28162770	TF1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10341173
54456140	54456163	5	+	28162770	TF1	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	NaN	[NaN]	[628]	1	hSpCas9	negative selection	10341174
54455897	54455920	5	+	28162770	TF1	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10341175
54455945	54455968	5	+	28162770	TF1	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	NaN	[NaN]	[437]	1	hSpCas9	negative selection	10341176
54455976	54455999	5	-	28162770	TF1	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10341177
54455838	54455861	5	+	28162770	TF1	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10341178
54455858	54455881	5	+	28162770	TF1	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10341179
54455967	54455990	5	+	28162770	SKM1	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	0.20547903840010145	[51]	[105]	2	hSpCas9	negative selection	10510536
54455995	54456018	5	-	28162770	SKM1	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.17308281156387806	[146]	[292]	1	hSpCas9	negative selection	10510537
54455911	54455934	5	-	28162770	SKM1	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	-0.6343746948462342	[35]	[40]	-5	hSpCas9	negative selection	10510538
54456029	54456052	5	-	28162770	SKM1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.7318038890504275	[30]	[32]	-5	hSpCas9	negative selection	10510539
54456140	54456163	5	+	28162770	SKM1	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.19221216119769524	[100]	[203]	1	hSpCas9	negative selection	10510540
54455897	54455920	5	+	28162770	SKM1	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.19661398014534143	[76]	[155]	2	hSpCas9	negative selection	10510541
54455945	54455968	5	+	28162770	SKM1	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	1.081490321124648	[84]	[317]	8	hSpCas9	negative selection	10510542
54455976	54455999	5	-	28162770	SKM1	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.26253181218966215	[57]	[122]	2	hSpCas9	negative selection	10510543
54455838	54455861	5	+	28162770	SKM1	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	-0.2891277084493035	[46]	[67]	-2	hSpCas9	negative selection	10510544
54455858	54455881	5	+	28162770	SKM1	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.03350580321571739	[21]	[37]	0	hSpCas9	negative selection	10510545
54455967	54455990	5	+	28162770	SKM1	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	0.20547903840010145	[51]	[105]	2	hSpCas9	negative selection	10679902
54455995	54456018	5	-	28162770	SKM1	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.17308281156387806	[146]	[292]	1	hSpCas9	negative selection	10679903
54455911	54455934	5	-	28162770	SKM1	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	-0.6343746948462342	[35]	[40]	-5	hSpCas9	negative selection	10679904
54456029	54456052	5	-	28162770	SKM1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.7318038890504275	[30]	[32]	-5	hSpCas9	negative selection	10679905
54456140	54456163	5	+	28162770	SKM1	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.19221216119769524	[100]	[203]	1	hSpCas9	negative selection	10679906
54455897	54455920	5	+	28162770	SKM1	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.19661398014534143	[76]	[155]	2	hSpCas9	negative selection	10679907
54455945	54455968	5	+	28162770	SKM1	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	1.081490321124648	[84]	[317]	8	hSpCas9	negative selection	10679908
54455976	54455999	5	-	28162770	SKM1	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.26253181218966215	[57]	[122]	2	hSpCas9	negative selection	10679909
54455838	54455861	5	+	28162770	SKM1	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	-0.2891277084493035	[46]	[67]	-2	hSpCas9	negative selection	10679910
54455858	54455881	5	+	28162770	SKM1	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.03350580321571739	[21]	[37]	0	hSpCas9	negative selection	10679911
54455967	54455990	5	+	28162770	PL21	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	1.5921218775404984	[204]	[268]	9	hSpCas9	negative selection	10849268
54455995	54456018	5	-	28162770	PL21	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	-0.3514642892854052	[512]	[174]	-3	hSpCas9	negative selection	10849269
54455911	54455934	5	-	28162770	PL21	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.011694525076209716	[97]	[42]	0	hSpCas9	negative selection	10849270
54456029	54456052	5	-	28162770	PL21	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.5641029291738946	[114]	[73]	5	hSpCas9	negative selection	10849271
54456140	54456163	5	+	28162770	PL21	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.7241778909295369	[394]	[283]	6	hSpCas9	negative selection	10849272
54455897	54455920	5	+	28162770	PL21	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.54578377835049	[180]	[114]	5	hSpCas9	negative selection	10849273
54455945	54455968	5	+	28162770	PL21	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.8966642826270292	[368]	[298]	7	hSpCas9	negative selection	10849274
54455976	54455999	5	-	28162770	PL21	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.06445530533209065	[184]	[76]	0	hSpCas9	negative selection	10849275
54455838	54455861	5	+	28162770	PL21	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.44270991776339846	[141]	[83]	4	hSpCas9	negative selection	10849276
54455858	54455881	5	+	28162770	PL21	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.24408296207691715	[96]	[49]	2	hSpCas9	negative selection	10849277
54455967	54455990	5	+	28162770	P31FUJ	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.02385531414288239	[153]	[177]	0	hSpCas9	negative selection	11018634
54455995	54456018	5	-	28162770	P31FUJ	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	-0.03876200496215265	[645]	[738]	0	hSpCas9	negative selection	11018635
54455911	54455934	5	-	28162770	P31FUJ	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.3173948781461011	[111]	[163]	3	hSpCas9	negative selection	11018636
54456029	54456052	5	-	28162770	P31FUJ	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.1724295864348968	[116]	[121]	-2	hSpCas9	negative selection	11018637
54456140	54456163	5	+	28162770	P31FUJ	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.3224686113699725	[359]	[528]	3	hSpCas9	negative selection	11018638
54455897	54455920	5	+	28162770	P31FUJ	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.14376114704982945	[170]	[221]	1	hSpCas9	negative selection	11018639
54455945	54455968	5	+	28162770	P31FUJ	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.2311448953454116	[550]	[759]	2	hSpCas9	negative selection	11018640
54455976	54455999	5	-	28162770	P31FUJ	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.6000878097503631	[223]	[398]	6	hSpCas9	negative selection	11018641
54455838	54455861	5	+	28162770	P31FUJ	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.9895902169220693	[143]	[335]	9	hSpCas9	negative selection	11018642
54455858	54455881	5	+	28162770	P31FUJ	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.03849981740301578	[86]	[104]	0	hSpCas9	negative selection	11018643
54455967	54455990	5	+	28162770	OCIAML5	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	0.06547126894402996	[134]	[254]	0	hSpCas9	negative selection	11188000
54455995	54456018	5	-	28162770	OCIAML5	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.32270783023971106	[329]	[744]	2	hSpCas9	negative selection	11188001
54455911	54455934	5	-	28162770	OCIAML5	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.015483133112353498	[56]	[103]	0	hSpCas9	negative selection	11188002
54456029	54456052	5	-	28162770	OCIAML5	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.46460579857187	[54]	[136]	4	hSpCas9	negative selection	11188003
54456140	54456163	5	+	28162770	OCIAML5	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.5588097053370061	[216]	[576]	5	hSpCas9	negative selection	11188004
54455897	54455920	5	+	28162770	OCIAML5	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.30692295289715993	[102]	[229]	2	hSpCas9	negative selection	11188005
54455945	54455968	5	+	28162770	OCIAML5	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.3946074061023501	[302]	[718]	3	hSpCas9	negative selection	11188006
54455976	54455999	5	-	28162770	OCIAML5	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.01548313311235372	[170]	[311]	0	hSpCas9	negative selection	11188007
54455838	54455861	5	+	28162770	OCIAML5	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.36023703284886704	[81]	[189]	3	hSpCas9	negative selection	11188008
54455858	54455881	5	+	28162770	OCIAML5	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.12508506527041297	[57]	[95]	-1	hSpCas9	negative selection	11188009
54455967	54455990	5	+	28162770	EOL1	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.7317993623873871	[434]	[137]	-5	hSpCas9	negative selection	11357366
54455995	54456018	5	-	28162770	EOL1	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.5308839230842577	[602]	[458]	5	hSpCas9	negative selection	11357367
54455911	54455934	5	-	28162770	EOL1	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	1.2575918986520709	[180]	[227]	9	hSpCas9	negative selection	11357368
54456029	54456052	5	-	28162770	EOL1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.2598963822202186	[213]	[134]	2	hSpCas9	negative selection	11357369
54456140	54456163	5	+	28162770	EOL1	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.4138316056437007	[586]	[411]	4	hSpCas9	negative selection	11357370
54455897	54455920	5	+	28162770	EOL1	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.08364980371831088	[445]	[248]	0	hSpCas9	negative selection	11357371
54455945	54455968	5	+	28162770	EOL1	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.07277770191352795	[535]	[296]	0	hSpCas9	negative selection	11357372
54455976	54455999	5	-	28162770	EOL1	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.9245477715705344	[230]	[230]	7	hSpCas9	negative selection	11357373
54455838	54455861	5	+	28162770	EOL1	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.22657630902019188	[145]	[89]	2	hSpCas9	negative selection	11357374
54455858	54455881	5	+	28162770	EOL1	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.08629884156714684	[58]	[32]	0	hSpCas9	negative selection	11357375
54455967	54455990	5	+	28162770	MOLM13	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	0.6447671436286582	[321]	[363]	5	hSpCas9	negative selection	11526732
54455995	54456018	5	-	28162770	MOLM13	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.12420431572254631	[617]	[486]	0	hSpCas9	negative selection	11526733
54455911	54455934	5	-	28162770	MOLM13	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	-0.7068850195591293	[148]	[65]	-4	hSpCas9	negative selection	11526734
54456029	54456052	5	-	28162770	MOLM13	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.8918600055934305	[160]	[431]	9	hSpCas9	negative selection	11526735
54456140	54456163	5	+	28162770	MOLM13	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	1.048412817099238	[433]	[648]	7	hSpCas9	negative selection	11526736
54455897	54455920	5	+	28162770	MOLM13	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.4914762018621947	[363]	[369]	3	hSpCas9	negative selection	11526737
54455945	54455968	5	+	28162770	MOLM13	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.6879378624127277	[527]	[614]	5	hSpCas9	negative selection	11526738
54455976	54455999	5	-	28162770	MOLM13	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.7214943744584419	[306]	[365]	5	hSpCas9	negative selection	11526739
54455838	54455861	5	+	28162770	MOLM13	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	1.5141830338185138	[137]	[284]	9	hSpCas9	negative selection	11526740
54455858	54455881	5	+	28162770	MOLM13	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.1278139399469571	[99]	[78]	0	hSpCas9	negative selection	11526741
54455967	54455990	5	+	28162770	HEL	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.0343683823101113	[298]	[186]	0	hSpCas9	negative selection	11696098
54455995	54456018	5	-	28162770	HEL	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.2649823488009726	[572]	[440]	2	hSpCas9	negative selection	11696099
54455911	54455934	5	-	28162770	HEL	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.9161151820556099	[138]	[167]	7	hSpCas9	negative selection	11696100
54456029	54456052	5	-	28162770	HEL	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-1.0136083019575648	[144]	[45]	-6	hSpCas9	negative selection	11696101
54456140	54456163	5	+	28162770	HEL	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.5844794340279614	[378]	[363]	5	hSpCas9	negative selection	11696102
54455897	54455920	5	+	28162770	HEL	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.32219196751135515	[260]	[208]	2	hSpCas9	negative selection	11696103
54455945	54455968	5	+	28162770	HEL	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	-0.04735003788749814	[433]	[268]	0	hSpCas9	negative selection	11696104
54455976	54455999	5	-	28162770	HEL	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.08008257984557932	[202]	[122]	0	hSpCas9	negative selection	11696105
54455838	54455861	5	+	28162770	HEL	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.28972305932889764	[128]	[100]	2	hSpCas9	negative selection	11696106
54455858	54455881	5	+	28162770	HEL	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-1.2317302859157844	[109]	[29]	-6	hSpCas9	negative selection	11696107
54455967	54455990	5	+	28162770	MV411	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.6085521465257056	[180]	[99]	-4	hSpCas9	negative selection	11865464
54455995	54456018	5	-	28162770	MV411	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.23879000216926372	[501]	[498]	2	hSpCas9	negative selection	11865465
54455911	54455934	5	-	28162770	MV411	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	-0.14570734264722607	[108]	[82]	-1	hSpCas9	negative selection	11865466
54456029	54456052	5	-	28162770	MV411	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.8124339051946233	[122]	[58]	-5	hSpCas9	negative selection	11865467
54456140	54456163	5	+	28162770	MV411	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.6003574601337642	[349]	[446]	5	hSpCas9	negative selection	11865468
54455897	54455920	5	+	28162770	MV411	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.5775861524751061	[279]	[351]	5	hSpCas9	negative selection	11865469
54455945	54455968	5	+	28162770	MV411	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.6835366655894487	[305]	[413]	6	hSpCas9	negative selection	11865470
54455976	54455999	5	-	28162770	MV411	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	0.7210011266680747	[156]	[217]	6	hSpCas9	negative selection	11865471
54455838	54455861	5	+	28162770	MV411	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.566259734802316	[92]	[115]	5	hSpCas9	negative selection	11865472
54455858	54455881	5	+	28162770	MV411	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.8131039911522755	[72]	[34]	-5	hSpCas9	negative selection	11865473
54455967	54455990	5	+	28162770	MONOMAC1	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	1.0390305111739706	[134]	[317]	8	hSpCas9	negative selection	12034830
54455995	54456018	5	-	28162770	MONOMAC1	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.028992316915781746	[282]	[330]	0	hSpCas9	negative selection	12034831
54455911	54455934	5	-	28162770	MONOMAC1	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.6816568567183128	[61]	[113]	6	hSpCas9	negative selection	12034832
54456029	54456052	5	-	28162770	MONOMAC1	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	-0.4217431342342481	[103]	[88]	-4	hSpCas9	negative selection	12034833
54456140	54456163	5	+	28162770	MONOMAC1	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.2911849988232522	[220]	[309]	3	hSpCas9	negative selection	12034834
54455897	54455920	5	+	28162770	MONOMAC1	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.14626489862037567	[133]	[169]	1	hSpCas9	negative selection	12034835
54455945	54455968	5	+	28162770	MONOMAC1	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.8589971878547741	[201]	[419]	7	hSpCas9	negative selection	12034836
54455976	54455999	5	-	28162770	MONOMAC1	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.9075302298645687	[143]	[87]	-6	hSpCas9	negative selection	12034837
54455838	54455861	5	+	28162770	MONOMAC1	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	-0.37457503261174124	[94]	[83]	-3	hSpCas9	negative selection	12034838
54455858	54455881	5	+	28162770	MONOMAC1	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.22874570678689166	[45]	[44]	-2	hSpCas9	negative selection	12034839
54455967	54455990	5	+	28162770	OCIAML2	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	0.10763802290498692	[35]	[214]	1	hSpCas9	negative selection	12204196
54455995	54456018	5	-	28162770	OCIAML2	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.2597631150005588	[87]	[583]	2	hSpCas9	negative selection	12204197
54455911	54455934	5	-	28162770	OCIAML2	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	0.6212926641988781	[18]	[161]	6	hSpCas9	negative selection	12204198
54456029	54456052	5	-	28162770	OCIAML2	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	1.0618652555848596	[20]	[242]	8	hSpCas9	negative selection	12204199
54456140	54456163	5	+	28162770	OCIAML2	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.6448473921777748	[62]	[545]	6	hSpCas9	negative selection	12204200
54455897	54455920	5	+	28162770	OCIAML2	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.7732957576439281	[37]	[359]	7	hSpCas9	negative selection	12204201
54455945	54455968	5	+	28162770	OCIAML2	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	1.1506745225427153	[48]	[602]	9	hSpCas9	negative selection	12204202
54455976	54455999	5	-	28162770	OCIAML2	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.3966292437983843	[37]	[159]	-3	hSpCas9	negative selection	12204203
54455838	54455861	5	+	28162770	OCIAML2	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.2054805635371903	[22]	[146]	2	hSpCas9	negative selection	12204204
54455858	54455881	5	+	28162770	OCIAML2	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	-0.1729492766014762	[11]	[58]	-1	hSpCas9	negative selection	12204205
54455967	54455990	5	+	28162770	OCIAML3	viability	GCAGAGACGCCACCCCGAGAAGG	HSPB3	ENSG00000169271	-0.533707130056349	[81]	[170]	-4	hSpCas9	negative selection	12373562
54455995	54456018	5	-	28162770	OCIAML3	viability	GTCCAGCAGGATCTGAAAGTGGG	HSPB3	ENSG00000169271	0.6470004591796317	[153]	[727]	6	hSpCas9	negative selection	12373563
54455911	54455934	5	-	28162770	OCIAML3	viability	GGTTTTCCTCAGGTCCACGATGG	HSPB3	ENSG00000169271	1.1990630557271935	[28]	[200]	8	hSpCas9	negative selection	12373564
54456029	54456052	5	-	28162770	OCIAML3	viability	GAATGATGATGTCTTCAGGGAGG	HSPB3	ENSG00000169271	0.1064320778169291	[31]	[103]	1	hSpCas9	negative selection	12373565
54456140	54456163	5	+	28162770	OCIAML3	viability	GTACAAACTACCAGATGGTGTGG	HSPB3	ENSG00000169271	0.18286667527867928	[81]	[280]	1	hSpCas9	negative selection	12373566
54455897	54455920	5	+	28162770	OCIAML3	viability	ACTGCCTGGGCCAACCATCGTGG	HSPB3	ENSG00000169271	0.20435849850618637	[68]	[239]	2	hSpCas9	negative selection	12373567
54455945	54455968	5	+	28162770	OCIAML3	viability	GTCTCCTCCAGTGGACTCAGCGG	HSPB3	ENSG00000169271	0.11648574248085186	[120]	[395]	1	hSpCas9	negative selection	12373568
54455976	54455999	5	-	28162770	OCIAML3	viability	TGGGATTTGCCTTCTCGGGGTGG	HSPB3	ENSG00000169271	-0.10858081315392137	[54]	[153]	-1	hSpCas9	negative selection	12373569
54455838	54455861	5	+	28162770	OCIAML3	viability	CAGGAAGAGTTTGAAGCTCGAGG	HSPB3	ENSG00000169271	0.9439573808598235	[25]	[150]	7	hSpCas9	negative selection	12373570
54455858	54455881	5	+	28162770	OCIAML3	viability	AGGTCTAGAAGACTGCAGGCTGG	HSPB3	ENSG00000169271	0.5473482089213784	[16]	[74]	5	hSpCas9	negative selection	12373571